KOBE Biomedical Innovation Cluster

If you are interested
in moving to Kobe, go to:
Up-to-date information is
available online
KOBE New Corporate Development
Department. Medical Industry Group. http://www.kobe-lsc.jp/en/
Kobe City Hall
6-5-1 Kano-cho Chuo-ku Kobe 650-8570, JAPAN
; +81-78-322-6341
F [email protected]
2015.3 City of Kobe Publication Record: No. 301 FY2014 (Printed publication Type A-1)
Kobe Biomedical Innvation Cluster
Search
National Strategic Special Zone
KOBE Biomedical
Innovation Cluster
Business Support Incentive
One of Japan’s Largest Biomedical Clusters
Kobe Biomedical Innovation Cluster
ing industrial fields in the 21st century, by inviting organizations belonging to the industry to the artificial island
named “Port Island” through collaborative efforts between
industry, academia and government since 1998. The City
of Kobe has promoted this project for 17 years. Currently,
“state-of-the-art” research institutions, highly specialized
hospitals, and more than 280 biomedical companies and
universities have entered this area to form one of the
largest biomedical clusters in Japan.
Companies in the Cluster
Number of companies
286
(as of Jan. 2015)
Number of employees
0
Clinical
institutions
150
101
France
Sanofi K.K. / Tornier Japan K.K. / emka
TECHNOLOGIES S.A.S.(Japan)
Korea
10 DR JAPAN Co., LTd. / HuBDIC-Global
UK
Belgium
0
2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
Chugoku
Kobe
Interational
Frontier
Medical
Center
(KIFMEC)
Sa n
Himeji
Kakogawa
line
yo E
x pre
s s wa
way
Spectris Co.,
Ltd.
IBP Inc. / Materialise
Japan K.K.
Ideal access to Kobe Biomedical Innovation Cluster via public transportation:
80 minutes from Haneda Airport in Tokyo
About 12 minutes from Sannomiya, or downtown Kobe
y
Kakogawa
Se
Sh c on d
Sa o S
inm
ny h i
ei
o nk
Ro
Ra a n
ad
ilw s e
ay n
Nishi2
ay
u te
Kobe-Awaji-Naruto
Expressway
am
aL
ine
Shin-Meishin Expressway
Osaka
Prefecture
s wa
xpres ine Mt. Rokko
L
hin E
Hans ita-Kobe
K
7
.
Railway
o
N
Hankyu
Mt. Maya
s w ay
Amagasaki
xpres
E
in
nsh
ine
Hanshin Railway
Shin-Kobe Ha . 3 Kobe L
No
Sannomiya
akashi
Akashi
Akashi
Strait Bridge
Awaji
Island
hiy
(via JR Kobe Line and Port Liner)
M
eis
Kobey City
ilw
ny
Ro
uc
Shinkansen
Kyoto
About 65 minutes
from Kyoto
Hyogo
Prefecture
Ra
Healthcare
E xpress
Fu
k
be
1
18
Germany
Nippon Boehringer Ingelheim Co.Ltd. /
Siemens Japan K.K.
50
Kobe
Kobe Minimally
Invasive
Cancer Center
Nursing care and rehabilitation
Medical equipment
Switzerland
100
85
32
Sa
(Companies)
Regenerative medicine
73
60
Nishi Memorial Port Island
Rehabilitation Hospital
Industrialization
200
SKAN JAPAN, K.K. / Electrosuisse Japan /
SYNTHES K.K.
150
125
Ko
(Hospitals)
INNOVATION
Pharmaceutical
and Biomedical
250
Harbor
Highway
Kobe Airport
(Marine Air)
hin
k
To
Ex
e
pr
ss
n
hi
wa
ka
y
ns
en
Li
aid
o
Ke L i n
iha e
nL
ine
Kobe City
Medical Center
General Hospital
Institute of
Biomedical Research
and Innovation
(IBRI)
233
China
Beauty and Health Innovation Co., Ltd./
BGI JAPAN / BGIHealthJAPAN
170
Excellent access to domestic
and overseas locations
RIKEN Advanced Institute
for Computational Science
(K computer)
(Research
institutions)
218
300
286
Location
Cluster for Innovation Creation
RIKEN Center for
Life Science
Technologies (CLST)
203
Number of companies
4,000
1,000
Accumulation of:
state-of-the-art research institutions,
highly specialized hospitals, and
medical companies
(as of Dec. 2014)
271
2,000
Basic
research
6,700
（Unit: company）
3,000
RIKEN Center for
Developmental
Biology (CDB)
About
7,000
5,000
July 1998
USA
Nihon Medi-physics Co., Ltd. / Bay bioscience
Co., Ltd. / Covidien Japan, St. Jude Medical, INC.
/ Johnson & Johnson K.K. / GE Healthcare/
EMERGO JAPAN Inc. / Zimmer K.K. / Simco
Japan Inc. / Intel Corporation
Number of employees
（Unit: person）
6,000
August 2014
List of
foreign affiliated companies
Number of companies and employees
a
o
id
S
To
k
The City of Kobe started the “Kobe Medical Industry
Development Project” as one of the earthquake restoration projects to recover the economy of Kobe which was
severely affected by the Great Hanshin-Awaji Earthquake
on January 17, 1995. Recognizing anew the “importance
of life”, Kobe was determined to promote a new industry,
protect the lives of citizens and contribute to international
society. The city has been engaged in the development of
an R&D hub for state-of-the-art biomedical technologies
and has promoted the medical industry, one of the grow-
Shin-Osaka
Se
co
ne
Keiji s
By pa s
a
eih
nR
o
ad
Shin-Kobe
Nagoya
Shin-Kobe
Hakata
Shin-Kobe
Umeda
Kyobashi
Osaka
Nara-Okuyama
Driveway
Nara
Han
No. shin E
x
5W
an g pres sw
an L
a
ine y
About 30 minutes from
Kansai International Airport
to Kobe Airport
Hanwa
Expressway
About 35 minutes
from Osaka
Address of Port Liner Iryo Center Stn.: 1-chome, Minatojima Nakamachi, Chuo-ku, Kobe
Port Liner
About
12 minutes
from
Sannomiya
(by Port Liner)
Kobe
Port Island
Iryo Center Stn.
Nara
Prefecture
(via JR Kobe line and Port Liner)
Wakayama
Prefecture
About
Sannomiya
Shimin
Hiroba Stn.
Kintetsu
Osaka Line
(by high-speed boat)
170 minutes
70 minutes
About 140 minutes
About
Shin-Kobe
K
nd Keihanna
Expressway
Kobe Biomedical Innovation Cluster
Kansai
International
Airport
Tokyo
K Computer Mae Stn.
About
5 minutes
from
Kobe Airport
(by Port Liner)
Kobe Airport
Kobe Airport
(10 flights/day)*
About 70 minutes
from Haneda
About 120 minutes from Shin-Chitose
About 90 minutes
from Sendai
*As of March, 2015
2
For Medical Industry Businesses, look no further
Kobe Biomedical Innovation Cluster
Kobe Biomedical Innovation Cluster
Central Area of
Kobe Biomedical Innovation Cluster
The Kobe Chamber of
Commerce & Industry
12
WORLD
Kobe International
Conference Center
Shimin
Hiroba Stn.
WORLD Hall
WDB
WORLD
Kobe Interational Frontier
Medical Center (KIFMEC)
Office
Office: 3,200 yen/㎡
Lab: 2,300 to 2,500 yen/㎡
Common service fee: 800 yen/㎡
OKLEX
KSM
KobeBio
Robotix
Yasojima
Proceed
3
IMDA
2
CDB
IBRI
Star Plastic
Industry
Medicine related companies
and universities
Quarter for cluster facilities
Companies and facilities
BT
BMA
TRI Anshin
Hospital
KIMEC
Kanae
Asubio
Pharma
Kita Futo Stn.
13
Port
Island
Kobe
Airport
Stn.
3
Sharable
equipment
Rooms
for SOHO
Office
Lab
Sharable
equipment
Rooms
for SOHO
Office
Sharable
equipment
Lab
Rooms
for SOHO
Rental rate (monthly price excluding tax)
Office and Lab: 3,000 yen/㎡
Common service fee: 1,000 yen/㎡
6
Kobe Healthcare Industry
Development Center
(HI-DEC)
Facilities: Animal lab, RI lab and cell culture center
Rental rate (monthly price excluding tax)
Rental rate (monthly price excluding tax)
Lab: 3,000 to 4,200 yen/㎡
Common service fee: included
Lab: 3,100 yen/㎡ CPC: 4,000 yen/㎡
Common service fee: 1,000 yen/㎡
7
Kobe Medical Device
Development Center
(MEDDEC)
Kobe Hybrid Business
Center (KHBC)
8
Lab
Sharable
equipment
Rooms
for SOHO
9
Kobe Incubation
Office (KIO)
Office
Lab
Sharable
equipment
Rooms
for SOHO
Rental rate (monthly price excluding tax)
Lab:4,400 yen/㎡
Common service fee: included
10
ITOCHU Medical Plaza
（IMP）
Office
Lab
Sharable
equipment
Rooms
for SOHO
Office
Rental rate (monthly price excluding tax)
Rooms
for SOHO
Facilities: Animal lab
Rental rate (monthly price excluding tax)
Lab:4,400 yen/㎡
Common service fee: included
Lab:4,400 yen/㎡
Common service fee: included
11
Port Island Building
Port Island (Phase I )
Sharable
equipment
operation room
MRI
Lab
12
Kobe International
Conference Center
Port Island (Phase I )
K Computer Mae Stn.
Integrated Research
Center of Kobe Univ.
(KUIRC)
Office
JASPEC
HR development & manufacturing
Nichii Gakkan
base for the next generation
KOBE
Company
biopharmaceuticals field
ANIMAL
(will be open in June 2015)
KINGDOM
Trans
Genic
Yanai
Primmune
TAKIRON
New Drug Research Center
Imagineering
Nissin
Pharmaceutical
Industries
Main form of business
Research institutions,
head/branch/field offices
Purpose category
Commercial district
Medical Device
8 Kobe
Development Center
↓Kobe Airport
Site for
manufacturing factories
Office: 2,200 to 3,300 yen/㎡
Common service fee: 600 yen/㎡
13
Office
Lab
Limit
Plot ratio
400％
200％
200％
900㎡
128,400 to 214,000 yen
2,000㎡
106,000 to 192,600 yen
* The colors correspond to those in the above map.
Rooms
for SOHO
Rental rate (monthly price excluding tax)
Office: 2,600 yen/㎡
Common service fee: 800 yen/㎡
(including tax)
Lab
Sharable
equipment
Rooms
for SOHO
Rental rate (monthly price excluding tax)
Office: 2,400 yen/㎡
Common service fee: 1,050 yen/㎡
(including tax)
Office
Lab
Sharable
equipment
Rooms
for SOHO
Rental rate (monthly price excluding tax)
Office: 2,600 yen/㎡
Common service fee: 1,300 yen/㎡
(including tax)
Office rental aid (not applicable to large companies)
Semi-industrial district
Lab
Office
Incentive for leasing offices
Industrial district or semi-industrial
district (suitable for factories)
Office
Rooms
for SOHO
3,800 yen/㎡
Common service fee: included
Aid rate
Sharable
equipment
Sharable
equipment
Rental rate (monthly price excluding tax)
Research institutions, and plants
and universities to which a
research institution is attached
60％
●The maximum discount rate varies by the area.
Rooms
for SOHO
Industrial
60％
175,000 to 350,000 yen
Sharable
equipment
Rental rate (monthly price excluding tax)
Site for research
and cultural facilities
80％
1,000㎡
Lab
Kita Futo Building
Port Island (Phase I )
(MEDDEC)
Building to land ratio
Sales price (per ㎡)
Office
site for discovery and development
center for innovative drugs
(tentative name)
Foundation for Computational
Science (FOCUS)/
University of Hyogo
Site for business operation
Minimum lot for sale or rent
Kobe Airport
9
KIO
FUKUDA DENSHI
RIKEN Advanced Institute for
Computational Science (K computer)
Naka Koen Stn.
5
Kobe KIMEC Center
Building (KIMEC)
Rental rate (monthly price excluding tax)
Office: 2,800 yen/㎡ Lab: 2,500 yen/㎡
Common service fee for office: 1,200 yen/㎡
(including tax)
Common service fee for lab: 1,000 yen/㎡
(including tax)
7
RIKEN Integrated Innovation
Building(IIB)
(will be open in 2015)
Nippon
Boehringer Ingelheim
Cyclochem
11
Minatojima
Stn.
RIKEN Center for Life Science
Technologies (CLST)
6
KAN Research Institute
CLST
KHBC
Number Three
Konan
University
5
SHINYEI
Minato
Medical
Science
Lab
4
4
TAKIGEN MFG
Oyama
Ophtecs
Corporation
Sanshodo
Wakenyaku
Bay bioscience
Kouai kagaku
Translational Research
Informatics Center (TRI)
Particle Beam
Treatment Facility
(will be open in 2017)
10
Office
3
Business Support
Center for Biomedical
Research Activities (BMA)
International Medical
Devive Alliance（IMDA）
SUZUKEN
DSPResearch
GA XROSSING
Seishine
Traiding
HI-DEC
KIBC
RIKEN Center for Developmental
Biology (CDB)
IMP
KIFMEC
NARD
MIYANO MEDICAL
1
Institute
INSTRUMENTS
Nihon
Nichiden-Rika Glass
Medi-physics
Bando Chemical
Industries
MORESCO
RF
MOKUDA
DENTAL KiSCO
Medical
Foods
Harmony
Hyogo Prefectural
Kobe Children's Hospital
(will be open in 2016)
Shimin Byoin
Mae Bldg.
Kobe City
Medical Center
Nissay Technology Corporation General Hospital
ECOUS Corp.
Japan Frozen
Adjuvant Cosme Japan
Food Inspection
Corporation
Towa
Phamaceutical
Rooms
for SOHO
Child Chemo
House
Iryo Center Stn.
Kobe Eye Center
(tentative name)
Sharable
equipment
Rental rate (monthly price excluding tax)
Kobe Minimally Invasive
Cancer Center
Nishi Memorial �Port Island
Rehabilitation Hospital
Lab
2
Shimin Byoin Mae
Building
（MRI）
Minami
Koen Stn.
Institute of Biomedical Research
and Innovation(IBRI)
1
Kobe International
Business Center
(KIBC)
WORLD
Portopia Hotel
Portopia Hall
Kobe International
Exhibition Hall
* All buildings have parking lots and conference rooms.
Naka
Futo Stn.
Sannnomiya↑
List of Buildings Available for Rent
Period
1/2 of rental
rate or less
1,500yen/㎡
2 million yen/year
3 years
Example
1
Aid:
138,600yen
Renting a lab space of
31.5㎡ in Kobe
Medical Equipment
Development Center
(excluding tax)
Monthly
rent
47,250yen
91,350yen
Actual
payment
(monthly)
Saving as much as 1,701,000 yen for 3 years
Example
2
Renting an office of
150㎡ in Kobe
KIMEC Center
Building
(excluding tax)
586,666yen
Monthly
rent
Aid:
166,666yen
420,000yen
Actual
payment
(monthly)
Saving as much as 6,000,000 yen for 3 years
* New applications may not be accepted when the budget of each year is reached.
* This rental aid may not be applicable depending on the line of business, business size, available facilities of the building, etc.
Contact Kobe City Hall for further information.
4
Diverse Advantages Gained by Joining Kobe Biomedical Innovation Cluster
Dramatic Progress of Business
Further
development
of sales
channels
Further development of your technology
Vigorous Support for
Industrialization
Industrialization of
your technology
and ideas in the
medical industry
Kobe Biomedical Innovation Cluster
By joining the
Kobe Biomedical
Innovation Cluster:
The “Promotional Platform for the Industrialization of
Medical Equipment” is used to offer a matching service
between clinical/on-site needs and companies
‘producer-driven solutions, and coordinate services
through which professional advisers are introduced.
Vigorous support is provided to promote industrialization
in the area of medical equipment.
Development of sales channels
Joint Exhibition in Domestic and
Overseas Trade Shows
The companies in the cluster have the
opportunity to participate in major trade
shows held overseas and the Tokyo
metropolitan district in Japan in
cooperation with other companies. Those
trade shows include MEDICA (medical
equipment trade show in Germany),
MEDTEC Japan (medical equipment trade
show in Tokyo) and BIOtech
(biotechnology trade show in Tokyo).
Acceleration of
research and
development
iPS cells and super computer
Various advantages in business
Leading-edge
Research Activities
In collaboration with outstanding
researchers and companies
Joint Research and
Development
Knowledge/information exchange
for business development
Cluster Exchange Meeting
and Workshops
Designated as National
Strategic Special Zone
You will enjoy
an extended
business
network.
The Cluster Exchange Meeting provides a place
for business matching (usually held every month).
After presentations/speeches are made,
participants have time to meet and greet each
other. In addition, the “Kobe Regeneration
Medicine Workshop” and “Kobe Port Island Drug
Discovery Forum” are held. The former is
participated in by researchers and companies
related to regeneration medicine, and the latter
was established by pharmaceutical companies.
Interview with Company in the Cluster
Tax benefits and
financially
preferential
treatment
Leading-edge research activities such as the
world’s first transplant surgery with the use of
iPS cells and the initiatives of in-silico drug
discovery using the K Computer are conducted
in the Kobe Biomedical Innovation Cluster.
interview01
Medicaroid Corporation
5
interview02
The first reason why we were attracted by Kobe is the presence of the Kansai’s core top academics; or
you could even say Japan’s core top academics. This academia includes RIKEN, the Foundation for
Biomedical Research and Innovation, Kobe University, Konan University and Kobe Gakuin University.
Actually, we have interviewed key doctors in many hospitals, and through doing so we understood what kind
of products doctors wanted us to produce. We realized that there were more needs than we expected. Some
other doctors kindly said that they would help us evaluate new products after production.
President
Since rental offices and facilities for temporary
use (for RI experiments and animal
experiments) are available, effective research
activities and business with reduced initial costs
are possible. In addition, various outsourcing
needs are satisfied due to highly professional
companies that provide a synthesis service on a
commission basis, supply model animals,
produce prototype models on a commission
basis and offer other services being located in
the Kobe Biomedical Innovation Cluster.
Q. Why did your company join the Kobe Biomedical Innovation Cluster?
A.
We are a medical robot technology company, and the viewpoint of users is our top priority. If we are not aware
of opinions of doctors and people in the public administration sector, we cannot go forward. In this regard, the
Kobe Biomedical Innovation Cluster is the best place to promote marketing, as many hospitals are located
here and generous support from the City of Kobe is available.
There are not only doctors but also business people from various companies here, and we are always actively
exchanging knowledge and information with them. We have opportunities to meet people from companies we
don’t know, and they tell us that they can do something new for us. We can meet new people here without
needing to find and visit them. The Kobe Biomedical Innovation Cluster has much to offer medical companies,
and we are taking full advantage of our place in the Cluster to produce top-class products.
The City of Kobe was designated as a National
Strategic Special Zone in May 2014. Regulatory
reforms and other measures are implemented
comprehensively and intensively to reinforce the
international competitiveness of various
industries and facilitate the development of the
base for international economic activities, by
concentrating on the promotion of structural
changes for the economic society.
Interview with Company in the Cluster
are the advantages of the Kobe Biomedical Innovation Cluster to
Q. What
your company?
A.
Yasuhiko Hashimoto
Responding to Various Needs
Relaxation of
regulations
You will be able
to collect
up-to-date
information.
Companies are conducting joint research and
development in collaboration with Japan’s
top-class academics in the cluster. The
established environment is provided to enable
leading-edge R&D activities and collection of
up-to-date information.
Cost benefits from idealistic
environment with a wealth of
equipment and facilities
Yoshiharu Minamitake
President & CEO
Asubio Pharma Co., Ltd.
In addition, our former research center was located in Yamazaki, on the border between Osaka
Prefecture and Kyoto Prefecture, and therefore Kobe is in an excellent location in terms of commuting.
There are also many high-quality Junior High Schools and High Schools in Kobe. Aside from education
and research, Kobe has a shopping and entertainment district called Sannomiya, and provides a
friendly environment where you can get to know other residents. As for child rearing, we can establish
a day-care center within a company with the help of the Kobe Municipal Government. Kobe offers us a
pleasant working environment.
The members of our company felt excited when we decided to move to Kobe.
6