Veterinary Formulas Product Guide

Transcription

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VETERINARY PROFESSIONAL’S
2016 Product Guide
Dear Veterinary Professional,
Thank you for choosing Standard Process as your supplement
company. Together, through our dedication and commitment,
we are able to affect the lives of millions of people and animals
throughout this country every day.
Standard Process has been a family-owned business for three
generations. I am proud to be the great-nephew of Dr. Royal Lee
and am honored to continue his legacy of changing lives through
whole food nutritional products. We are dedicated to building on
the solid foundation Dr. Lee created, ensuring that the patient
comes first. It is a privilege to work with you to accomplish this
goal. We will continue our focus on the veterinary professional in
the future.
At Standard Process, we continue to invest in our manufacturing facility, making sure we deliver
quality products by controlling the process from beginning to end. Innovative technology and
continual improvement ensure we deliver a product that is as close as possible to how nature
intended. Our certified organic farm provides us with the starting point for our raw materials.
As Dr. Lee said, “The best source of nutrients comes from whole foods.”
We are excited to expand our research and development efforts in the coming year, concentrating
on ways to validate Dr. Lee’s nutritional philosophy, which was ahead of its time. There has been
considerable growth and interest in Cultivate by Standard Process, our corporate wellness offering,
as well as Lee Engineering, a company Dr. Lee founded in 1927.
Standard Process continues to invest in our greatest asset—our employees. This amazing team
makes whole food nutrient solutions possible for you and your patients. I am very proud of
these talented, dedicated and caring people, whose primary role here at Standard Process is to
Change Lives.
We are a Family Business, with Family Values, and are glad to call all of you a part of the
Standard Process Family.
Yours in health,
Charles C. DuBois
President and CEO
Our Mission
Standard Process is the visionary leader in whole
food nutrient solutions. We apply systems thinking
to holistic nutrition that empowers practitioners to
transform lives.
Our Corporate Values
Standard Process demonstrates
commitment to the Whole:
Person
Product
Process
Planet
Posterity
By fostering
the physical,
emotional,
intellectual, and
spiritual health
of customers and
employees
By emphasizing
the importance
of concentrated
whole food
ingredient
sources and
herbs in the
product line
By ensuring the
highest quality
in every stage
of development,
from farming
through shipping
By utilizing
environmentally
safe farming,
manufacturing,
and business
practices
By preserving and
strengthening
the company
for all future
generations
Whole Food Nutrient Solutions | standardprocess.com | 800-558-8740
Beets
Alfalfa
Kidney Bean
Pea Vine
Contents
6 Why Whole Food Nutrition
10 About Us
21 Product Guide
58 References, Glossary, and FAQs
68 Contact Us
Standard Process and other trademarks, logos, etc., owned by Standard Process are registered trademarks of Standard Process Inc.
This guide is for veterinary professional use only. Clients should consult with a veterinary professional before feeding any products to animals.
Why Whole Food Nutrition
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Buckwheat on the Standard Process certified organic farm
Your clients bring their animals to you for many
reasons such as digestion issues, fatigue, and skin
challenges, just to name a few. Many of their
complaints may have a nutritional component.
“ The best sources of
vitamins and minerals
are found in whole foods.
—Dr. Royal Lee, founder of Standard Process
Dogs, cats, and horses have individual
nutritional needs beyond what their regular diet
provides, based on their age, activity level, and
health status. These patients may benefit from
supplementing their diets.
Nutrition and the relationship between food and
a healthy body are more important than ever.
Knowing how nutrients are digested, absorbed,
transported, metabolized, stored, and eliminated
by the body helps you communicate nutrition’s
significant role in many health challenges. This
knowledge also helps you to explain how the
complexity of whole food and other ingredients
in our supplements can support your patients.*
Whole Food Nutrient Solutions
and Your Patients
Buckwheat field on the Standard Process certified organic farm
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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Choose Wisely
Selecting a Supplement
Are whole food nutrient
complexes included?
Alfalfa
There is a great health value that comes from
the nutrient complexes found in whole foods.
Dr. Royal Lee referred to this as “the life element,”
and it can be produced only through biological
processes. That is why we start with the highestquality whole food ingredients when making our
supplements. These ingredients contain complex
structures that combine a variety of elements that
work together to support healthy balance in the
body. Other targeted ingredients are added to
formulas as needed to support specific systems
in the body.*
Is it comprehensive?
Beet
Peas
8
When we consider supplements, we often think
that more is better and try to megadose. However,
when choosing supplements, quality is far more
important than quantity. Supplements that
contain only synthetic vitamins have just a
fraction of the beneficial compounds that are
found in foods. Those supplements may only
address certain challenges in the body.
Supplements that include whole food ingredients
are more complex. These supplements contain a
mix of constituents that can be used to address a
wider range of the body’s needs.*
Whole Foods and the
Whole Food Philosophy
As in any recipe, the quality of ingredients affects
the quality of the final product. Manufacturers
who grow their own ingredients have control over
them, which is why Standard Process owns a
certified organic farm. But for items we can’t grow,
Standard Process has an extensive, rigorous
system of supplier auditing and validation. This
allows us to provide patients with a product that
has been controlled, vetted, tested, and verified
from beginning to end.
Since 1929, Standard Process has been the
visionary leader in whole food nutrient solutions.
We are dedicated to creating quality supplements
based on the whole food philosophy introduced by
our founder, Dr. Royal Lee. Dr. Lee’s goal was to
provide nutrients as they are found in nature—in a
whole food state where he believed their natural
potency and efficacy would be realized. Our goal is
to carry on his mission, incorporating whole food
ingredients along with targeted vitamins and
minerals for a holistic formula.
Vital Factors Within Raw Materials
We promptly process the crops harvested from our
farm to minimize the loss of phytonutrients and
deliver the complex nutrient content.
Some types of processing can destroy enzymes
and phytonutrients. Our manufacturing process
is designed to retain vital nutrients within
each ingredient.
Quality of Ingredients:
Going Beyond the Label
Starting With Whole Foods
Following this philosophy, we start with whole
foods—foods you might find in the grocery store,
like peas, radishes, and beets. Then, like any good
cook, we prepare these ingredients in a way that
safeguards their nutritional value. The resulting
whole food ingredient is then added to a complex
formula that may include whole food extracts,
animal tissue extracts and concentrates, botanicals,
whole food isolates, and synthetic ingredients as
required to meet high formula standards.
Buckwheat
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About Us
Defining Quality
Whole Food Supplement—a complex formula of targeted ingredients
that may include the following:
Whole Food Ingredients—complete foods
that are prepared in a way that safeguards
their nutritional value
If you read our product labels, you will find many
ingredients that you recognize as foods. Some of
these whole food ingredient sources are regularly
grown locally on our certified organic farm,
including alfalfa, barley grass, beets, Brussels
sprouts, buckwheat, kale, kidney beans, oats, pea
vine, Spanish black radish, and sweet potatoes. This
allows us to control the quality of these ingredients
from seed to supplement.
Whole Food Concentrate—processed part
of a whole food containing two or more
constituents of the original whole food
These concentrates are used when a beneficial
concentration of nutrients cannot be obtained using
a whole food ingredient. Fish oil is a good example; it
is derived from whole fish, and the nonconcentrated
triglyceride oil that makes up our final product
allows patients to take advantage of the naturally
occurring DHA and EPA omega-3 fatty acids.
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Animal Tissue Extracts and
Concentrates—whole food ingredients
derived from bovine, ovine, and
porcine sources
The use of specific animal tissue has a long history
at Standard Process. The first product based on a
Protomorphogen™ brand extract was introduced in
1952 and contained bovine heart PMG™ extract. Why
do we start with glands and organs? These tissues
are inherently different from skeletal muscle. Organ
meats have more DNA per gram than skeletal
muscle, different protein profiles, and different
starting concentrations of vitamins and minerals.
All raw animal tissues are obtained exclusively
from U.S. Department of Agriculture (USDA)inspected facilities.
Protomorphogen™ Brand Extracts
Continuing the pioneering work of Dr. Royal Lee,
certain Standard Process products contain specific
Protomorphogen™ brand extracts. Protomorphogen™
brand extracts are specific material extracted from
animal glands and organs through a complex,
multistep process to retain what Dr. Lee termed
“cellular determinants.” Current laboratory methods
have confirmed that Protomorphogen™ brand
extracts contain minerals, nucleotides (the
components of nucleic acids like RNA and DNA), and
peptides (short chains of amino acids).
About Us
For more than 85 years, Standard Process has provided health care professionals with high-quality nutritional
supplements made with whole food and other ingredients. Our product formulas contain unique combinations of complex
ingredients to provide specific nutritional support to the body. Standard Process meets the most demanding quality
standards set by federal and state agencies, as well as by our own internal production and quality control departments.
Cytosol™ Brand Extracts
Cytosol™ brand extracts are derived from the
cytoplasm of selected organs and glands through a
process similar to the Protomorphogen™ extraction
process. However, these extracts contain cellular
factors such as hormone precursors and synergistic
cofactors that are the biochemical building blocks
essential to cellular metabolism.
Whole Desiccates
Whole desiccates are whole tissues that have been
dried to provide the nutritional content of the organ
in a concentrated form.
Botanicals—plants and their extracts with
health-supporting properties
Isolates like glucosamine are used in our products
because they are well researched and have strong
evidence for efficacy. Isolates derived from whole
food sources are combined with other ingredients to
maximize their efficacy.
Synthetic Ingredients—a nutrient
produced by chemical means
We know Dr. Lee included synthetics in his original
formulas to meet label claims and/or enhance
product effects. Historically and still today, this type
of ingredient is used selectively. Where synthetics
appear, they have been added to protect the
complexity and synergistic design of the formula.*
Botanicals provide important factors that contribute
additional support to the body’s systems by
complementing the vitamins, minerals, and tissue
concentrates found in whole food ingredients.
Whole Food Isolates—single components
from a whole food
Sometimes levels of specific nutrients are not
available in sufficient quantities in foods to address
certain health challenges. In this case, we use
evidence-based food isolates to complement whole
food ingredients for optimal nutritional support.
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About Us
A drainage culvert (left) carries water from our farm’s underground tile system into a drainage field. Tile drainage helps remove excess
water from the soil to maintain optimum growing conditions. At right, this nesting box provides cover for a family of tree swallows every
season. Tree swallows live on a diet of insects and provide natural protection for our cerified organic farm.
Certified Organic Farming
“Whole food nutrition begins with sun,
water, and fertile soil.” —Dr. Royal Lee
Our founder, Dr. Lee, emphasized the importance
of producing high-quality supplements made with
whole food ingredients. We are proud to be one of
the few supplement manufacturers that can assure
quality ingredients by continuing our tradition
of growing many of our raw materials locally
and organically.
Nutrition Begins With the Soil
The glacial formations of Wisconsin’s Kettle
Moraine contain nutrient-rich soil. It is here, on
certified organic farmland, that we grow strong,
vital plants for use in our supplements. We
regularly grow the following crops: alfalfa, barley
grass, beets, Brussels sprouts, buckwheat, kale,
kidney beans, oats, pea vine, Spanish black radish,
and sweet potatoes.
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Organic Farming Methods
Nature has provided the foundation, and we use
organic farming practices to ensure that the quality
of our farmland is maintained for years to come. In
accordance with our organic certification, we follow
strict guidelines to grow our crops, keeping detailed
records of our farming practices. Our farmland is
monitored annually by the Midwest Organic
Services Association (MOSA) to ensure that only
the approved farming practices are used. At
Standard Process, we are involved from the moment
a seed is planted through shipping the finished
product to your door.
Seeds
There is zero tolerance in an organic system for
genetic modification. On our certified organic farm,
all the crops are not genetically modified organisms
(GMO). We use certified organic seeds whenever
they are available, whether they are purchased or
saved from our own farm. Untreated, GMO-free seed
is an option but is considered only after a diligent
search is conducted and it is determined that
certified organic seed is not available. Organic
farming has been part of our culture for more than
85 years.
About Us
To attract bees, tree lines along the Standard Process farm are kept intact, and plants are blooming from spring to fall in a native
pollinator garden. The habitat is home to more than 500 plants of 35 different varieties that attract insects to the farm.
Soil
We take soil samples annually to determine
mineral and nutrient levels in the soil. We never
use any synthetic fertilizers or pesticides in the
organic growing process.
Irrigation
When irrigation is necessary, water is supplied
from a naturally occurring artesian flowage below
the farm’s surface.
Weed Control
Like all farmers who strictly adhere to organic
weed-control standards, we spend many of our days
managing weeds. There is no simple approach, just
a comprehensive one that includes cultivating,
mowing, and hand weeding. To minimize weeds, we
grow cover crops and institute crop rotation. These
practices have additional benefits: Cover crops are a
great source of nitrogen and organic matter, and
crop rotation helps maintain the health of the soil.
Pollination
Colony collapse disorder has had a catastrophic
effect on the honeybee population in the United
States and threatens the pollination of our
fruits and vegetables. That’s why our farm has
planted over 500 plants of 35 different varieties
in a permanent habitat for honeybees and
other pollinators.
Composting
It is a goal of every organic farm to increase
fertility and improve soil health. That’s why we
use the biological process of composting to turn
organic production waste from the farm’s press
room into a rich and extremely fertile humus-like
substance that we spread over our fields.
Environmental Buffers
Our farm is surrounded on all sides by
environmental buffers to minimize the impact of
nonagricultural land and synthetic inputs from
conventional farming practices.
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About Us
Manufacturing
Dr. Royal Lee, founder of Standard Process, said,
“Whole foods are the best natural source of
vitamins. The key to the highest quality is the
manufacturing process.” Because preserving the
whole food complex is a top priority when
manufacturing our supplements, we base our
formulas on Dr. Lee’s time-proven philosophies.
Throughout the process, raw materials are
handled in a carefully controlled environment
and tested for quality.
Exclusive Manufacturing Processes
Each process is designed to preserve nutrients in
raw materials.
Juice Extraction
To capture the nutrients from raw materials such as
buckwheat, alfalfa, and pea vine, the juice is pressed
from the plants and separated from the pulp. The
result is a concentrated product containing both
fat- and water-soluble nutrients.
Separation Process
Selected animal tissues used to make our
Protomorphogen™ and Cytosol™ extracts are ground
to create a liquid slurry. The slurry is subjected to
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our proprietary multistep separation methods. All
raw animal tissues are obtained exclusively from
USDA-inspected facilities.
Dryers
To safeguard the complexity of our raw materials,
we use equipment that allows for accurate
temperatures and highly reproducible processes.
◆◆ Double
drum: dries extracts from both plant and
animal tissues
◆◆ Forced air: a multistage forced-air belt dryer that
works like a sophisticated food dehydrator
Continuing the Process
We use isolated production suites for the following
processes. These suites enhance cleanliness and
reduce the risk of cross-contamination in the
manufacturing area.
Mixing
Dried materials are precisely measured and
carefully mixed. Because of the variability in
natural and organic ingredients, color, texture, and
smell may vary from batch to batch. However, the
basic formula remains constant, and quality is
ensured by testing.
About Us
Binding and Processing Aids
After mixing, our fluid bed granulator is used to add
natural binding ingredients, such as honey and
arabic gum, to the product batch for tableting. Other
processing aids we use include cellulose and calcium
stearate. Cellulose is often used to give body to the
powders. When needed, calcium stearate, derived
from vegetable sources, is used to help product
release from the tablet machines. No artificial
flavoring is ever used.
Forms of Delivery
Tablets and wafers—The presses used by Standard
Process allow for high-volume production without
sacrificing quality. All of our finished tablets and
wafers are routinely analyzed for content to ensure
that label claims are accurate.
Powders—We use a volumetric filler, which achieves
very accurate fill amounts, for our powder formulas.
Cleaning
In between product runs, all of the equipment used
in our manufacturing process is taken apart, cleaned,
and sanitized. Adenosine triphosphate (ATP) testing
is used to validate the effectiveness of the
equipment-cleaning process. In addition, the
surrounding production suite, including the floors,
walls, and vent covers, is cleaned.
Environmental Program
In order to monitor the general level of
manufacturing hygiene, Standard Process has
implemented an environmental monitoring program
for the facility. The program highlights the presence
of any foodborne pathogen that may be in the facility
and determines the source of these pathogens.
Routine meetings between production and quality
control are held to maintain the highest level of
cleanliness throughout all areas of the facility.
Packaging
Our products are sealed in either amber glass bottles
or bisphenol A (BPA)-free bottles made of
polyethylene terephthalate (PET) plastic. The color of
the bottles helps protect the supplements' nutrients
from damaging light, while the sealed bottle helps
prevent product oxidation. Tamper-resistant seals
and neckbands protect against product interference.
The majority of the products are then packaged in
eco-friendly cardboard boxes, providing easy storage,
protection, and shipping.
15
About Us
Quality Control
Standard Process takes great pride in its quality
control program. Since the good manufacturing
practices (GMPs) for dietary supplements were
published in 2007, many companies began to look at
quality in the way Standard Process has been doing
for decades.
Our team of highly trained and degreed
microbiologists and chemists work meticulously to
guarantee our customers receive quality products.
Our quality control unit ensures our label claims are
met and confirms products are free of bacterial
contamination by testing after critical stages of
production. Shelf-life studies are also conducted on
each product to make certain that label claims are
met throughout the life of the product.
Quality Assurance
We use high-performance thin-layer
chromatography (HPTLC) to identify incoming raw
materials and in-process materials and qualify them
based on consistency, potency, and purity. HPTLC is
used to create a unique banding pattern, or
“fingerprint,” by isolating key chemical constituents
to aid in identification of these materials.
Quality Audits
We work very closely with our suppliers, using a
questionnaire for qualification and an auditing
program designed to improve operations. Planned
site visits are conducted 12-14 times per year based
on risk analysis. Our purchasing department looks
at things like on-time delivery, customer service,
and invoicing.
Testing
Testing of every batch is repeated in various stages
throughout the manufacturing process to ensure
quality and safety of our products. On average, a
batch is tested six times. Every week, our scientists
in our full-scale quality control laboratory run as
many as 1,100 tests on raw materials, in-process
product batches, and finished product. We use
analytical methods approved by nationally
recognized evaluative bodies, including the
Association of Analytical Communities (AOAC) and
United States Pharmacopeia (USP).
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Laboratory Information Management System (LIMS)
Standard Process’ quality control department has fully
validated and implemented the Nexxis iLAB laboratory
integrated management system (LIMS) by Labtronics.
The system allows for a centralized storage location for
all data analysis conducted by the laboratory. This
implementation has improved data analysis by
ensuring quality and accuracy of results, providing
real-time data retrieval, preventing data errors,
automating manual calculations, and allowing for lab
data to be accessed throughout the facility.
Chemistry
Standard Process chemists perform multiple assays to
guarantee that our products meet or exceed label
claims and to ensure the viability of the product
through its “Best Used By” date. We use the following
instrumentation in testing raw materials and final
product mixes:
High-Performance Liquid Chromatography (HPLC)
vitamins A, E, B6, B12, C, D; niacin; folic acid
Gas Chromatography (GC)
solvents
Inductively Coupled Plasma (ICP)
minerals, heavy metals
High-Performance Thin-Layer Chromatography (HPTLC)
botanical identification
Fourier Transform Infrared Spectroscopy (FTIR)
raw material identification
LECO®
protein analyzer
The chemistry laboratory personnel also conduct wet
chemistry tests for a variety of things, such as vitamins
B1 and B2, pepsin, bile salts, water activity, moisture,
carotene, iodine, phosphorous, and chloride. The vast
testing capability of the chemistry laboratory allows
Standard Process to verify the identity, purity, and
strength of our products and of the raw materials used
in our products.
Manufacturing
Our microbiologists test for pathogens in every
product batch to ensure the products are safe to
continue to the next stage of production. Testing is
conducted on all facets of the manufacturing process,
including raw materials, mixing, milling, tableting,
capsuling, and packaging. Raw materials, in-process
products, and final products are only released to the
next stage of production by the quality control unit
upon verification that the material or product has
passed all testing requirements.
Many tests are performed, including:
About Us
Microbiology
◆◆ Tablets
are monitored for size, weight, water
activity, and hardness. Hardness testing ensures
that tablets remain intact throughout the packaging
and shipping process. Weights are verified to
guarantee that label claims are met.
◆◆ Powders are monitored for water activity.
Farm
Soil samples are taken annually to determine
mineral and nutrient levels of the soil. No synthetic
fertilizers or pesticides are ever used in the organic
growing process.
Each product batch
is tested an average
of six times.
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18
About Us
The genius of Dr. Royal Lee was his ability to
observe specific attributes of complex machines and
behaviors within human health. He applied this
approach directly to his groundbreaking work in
nutrition. Dr. Lee understood the value of research
on whole food supplementation. Throughout his life
he field-tested, endorsed, and supported clinical
evaluations of his unique nutritional supplements.
About Us
Research and Development at Standard Process
Building the Future
We build on Dr. Lee’s holistic philosophy toward
research and development by applying the latest
technology and expertise through a systems
approach to research.
Our mission
To develop and expand innovative research in
alignment with Standard Process’ mission to address
health and wellness through holistic nutrition
Our vision
To be the best-in-class research and development
team that conducts world-class basic and applied
research that contributes to Standard Process’
growth and benefits mankind
Applied Clinical Research
We design and fund a number of studies, including
double-blind, randomized, and placebo-controlled
clinical trials. Our clinical research team currently
collaborates with academic, clinical, and contract
research organizations to explore and study the
impact of Standard Process supplements on
human health.
Discovery Science and Technology:
Metabolomics and Genomics
Because complex ingredients require sophisticated
investigation, we explore ingredient and product
complexity through metabolomics and genomics. In
the past, our discovery science group explored this
complexity by characterizing ingredients
(buckwheat, carrots, and Spanish black radish),
scrutinizing the chemicals that were likely the most
bioactive and testing their activity using in vitro and
in vivo in cell and animal models.
While that strategy produced informative results,
new technology makes it feasible to embrace the
A Standard Process researcher examines cells.
complexity of our whole food-sourced ingredients
and products. Genomics and metabolomics
investigations use sophisticated analysis to look at
the interplay between a substance and the body in
real time. Genomics is the study of how genes act in
concert with one another and the environment.
Metabolomics is the "systematic study of the unique
chemical fingerprints that specific cellular processes
leave behind," the study of their small-molecule
metabolite profiles.1 These combined approaches
allow us to look at an organism as a whole and tease
out effects in animal and cell models that could be
applied to product development and clinical trials.
Innovation and Development of
New Products
Standard Process utilizes state-of-the-art approaches
and techniques in developing new products and
technologies. These methodologies rely on
exploiting scientific tools for the ideation, predesign, design and formulation, assessment, and
evaluation of product concepts through
commercialization. The process of product
development—apart from the rendered health
benefits assessment through in vitro and in vivo
testing and clinical and nonclinical trials—
encompasses the evaluation of the quality of whole
food raw materials, functional performance of the
combined ingredients, and finally, various rigorous
shelf-life and stability testing of the formulated
product. The final product should meet the highest
quality standards.
1. Daviss, Bennett (April 2005). "Growing pains for metabolomics." The Scientist 19 (8): 25-28.
19
About Us
Standard Process scientists work meticulously to ensure product quality and safety.
Organic Farming and Technical
Operations Processing
We research processing and organic farming
innovations to provide scientific perspectives on
processing and manufacturing efforts. The
technical operations team has broad training in
the fields of unit operations, nutrition,
phytochemistry, food chemistry, and processing.
Through investments in next-generation
technology and strategic partnerships, the
technical operations team helps to create the next
generation of whole food dietary supplement
ingredients. From soil health to the manufacture
of final product, the team looks to maximize
whole food nutrition at every step of the process.
The team also:
◆◆ Provides
rigorous scientific scrutiny during
raw material development, in partnership with
the Standard Process organic farm and the
quality control auditing program
◆◆ Offers scientific guidance on projects in the
quality control, engineering, marketing, and
production departments
◆◆ Evaluates new processing technologies
◆◆ Shepherds new products through the
development process
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Analytical Chemistry and Services Group
This group’s mission is focused on the development
of novel qualitative and quantitative measurement
techniques that are used to explore chemical
samples and thereby advance our understanding of
fundamental processes in science and technology.
Historically, the field of analytical chemistry was
categorized in terms of basic instrumental
techniques such as electrochemistry, optical
spectroscopy, separation, and mass spectrometry.
Modern analytical chemistry tends to be organized
more around interdisciplinary research areas in
biology, protein chemistry, and materials science.
The group has broad expertise in the development
and validation of analytical assays and techniques
in support of product and process development as
well as discovery and innovation. Significant
research is focused on polymerase chain reaction
(PCR) assays of regulatory and diagnostic
significance to the dietary supplement industry. In
collaboration with the quality control department,
the group is responsible for the development of
stability and shelf-life protocols of all new products.
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Veterinary Formulas for Pets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
VF Antronex® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Product Guide
Product Guide
VF Bio-Dent® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
VF Thymex® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
Canine Formulas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Canine Adrenal Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Canine Cardiac Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Canine Dermal Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Canine Enteric Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
Canine Flex Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Canine Hepatic Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
Canine Immune System Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Canine Musculoskeletal Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
Canine Renal Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Canine Thyroid Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
Canine Whole Body Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Feline Formulas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
Feline Cardiac Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Feline Enteric Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42
Feline Hepatic Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
Feline Immune System Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44
Feline Renal Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
Feline Whole Body Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
Equine Formulas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Equine GI Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
Equine Immune Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
Equine Metabolic Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
Equine Mobility Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54
Equine Performance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
23
Veterinary Formulas for Pets
Designed for both dogs and cats, these formulas contain a variety
of whole food and other ingredients. These products are available
in tablet form and can accommodate a range of body weights.
24
Please consult the product packaging label for the most accurate product information.
When the body’s natural histamine response function kicks in,
other systems are affected, including the immune system and
the liver. Building up defenses helps make sure these systems
are working at optimal levels to support pet health.
VF Antronex:
◆◆ Supports
the liver and the body’s normal
detoxification mechanisms*
Indications for Use
VF Antronex®
◆◆ Clinical
signs associated with liver challenges
in need of additional hepatic support
◆◆ Short- or long-term support for patients
influenced by environmental, seasonal
and other stresses
◆◆ Patients
Adjunctive Products
◆◆ Canine
Dermal Support
or Feline Immune
System Support
◆◆ Canine or Feline Enteric Support
◆◆ Canine
Supplement Facts
Stated amounts depend on dose.
Ingredients
Calcium lactate, bovine liver fat extract (yakriton), and vitamin E (sunflower).
Other Ingredients
Calcium stearate and arabic gum as tableting aids.
Minerals
Calcium . . . . . 40 mg / tablet
Content
Product No.
90 tablets . . . . A3010
Dose Schedule
Based on body weight, the patient should receive the formula according to
the following recommendations, or as otherwise directed.
All cats, dogs <20 lbs.. . . . . . . . . 1 tablet/day
Dogs 20-50 lbs.. . . . . . . . . . . . . . 1 tablet 2x/day
Dogs >51 lbs. . . . . . . . . . . . . . . . 1 tablets 3x/day
25
VF Bio-Dent®
Nutrition is a powerful tool to support pet oral health. VF Bio-Dent contains
calcium, phosphorus, and manganese for support of the bony structures and
connective tissue in the body, including the mouth. The formula also contains
complex food-based ingredients that provide support for endocrine and
immune system health.
VF Bio-Dent:
◆◆ Contains
many of the building blocks needed to support and maintain
oral health
◆◆ Provides systemic support for an overall healthy mouth, especially in an
orally challenged animal
◆◆ Provides building blocks for young animals that are experiencing tooth
and bone growth and development*
Indications for Use
◆◆ Support
for normal growth and
development of bone and the
oral cavity
◆◆ Support for the health of
oral tissues
◆◆ Support for the oral cavity
particularly in times of stress
Adjunctive Products
◆◆ Canine
or Feline Immune
System Support
Supplement Facts
Ingredients
Bovine bone, defatted wheat (germ), calcium lactate, carrot (root),
veal bone, bovine adrenal, bovine spleen, ovine spleen, manganese
glycerophosphate, sweet potato, licorice (root), and rice (bran).
Other Ingredients
Honey, cellulose, calcium stearate, and arabic gum as tableting aids.
Minerals
Calcium . . . . . 20 mg / tablet
Phosphorus . . 10 mg / tablet
Manganese . . . 1.4 mg / tablet
Content
Product No.
90 tablets . . . . A3000
Dose Schedule
All cats, dogs <20 lbs.. . . . . . . . . 1 tablet 2x/day
Dogs 20-50 lbs.. . . . . . . . . . . . . . 2 tablets 2x/day
26
Nutrition is a powerful tool to support pet immune system health. VF Thymex
supports a healthy thymus gland, the master gland of the immune system.
VF Thymex:
◆◆ Can
be used in combination with other immune system support products
source of antioxidant vitamin C*
◆◆ Good
Indications for Use
◆◆ Patients
in need of additional
immune system support
◆◆ Patients in need of
generalized trophic immune
system support
◆◆ Patients with short-term or ongoing
immune system challenges
VF Thymex®
Adjunctive Products
◆◆ Canine
or Feline Immune
System Support
◆◆ Canine or Feline
Hepatic Support
◆◆ Canine or Feline Whole
Body Support
Supplement Facts
Ingredients
Calcium lactate, bovine thymus Cytosol™ extract, magnesium citrate, and
ascorbic acid.
Other Ingredients
Cellulose and calcium stearate as tableting aids.
Content
Product No.
90 tablets. . . . A3020
Dose Schedule
All cats, dogs <20 lbs.. . . . . . . . . 1 tablet 3x/day
Dogs 20-50 lbs.. . . . . . . . . . . . . . 2 tablets 3x/day
27
Canine Formulas
Canine Formulas
Since dogs are omnivores, the canine formulas contain a variety of ingredients, including a
balance of animal tissues and botanical materials. These ingredient combinations provide a
spectrum of nutrients to support multiple organs. Most of the canine formulas are
powdered to accommodate the range of body weights in the canine population.
28
The adrenal glands help the body adapt to stress through the release of corticosteroids and hormones.
With chronic stress, the adrenals can become fatigued, affecting many body systems, including the
pituitary and thyroid glands, autonomic nervous system, liver, duodenum, and kidneys.
Canine Adrenal Support is formulated to:
Canine Formulas
Canine Adrenal Support
◆◆ Help
adrenal glands respond normally to stress and metabolic demands
the glands’ ability to rebuild and regenerate
◆◆ Provide vital nutritional support to related organs*
◆◆ Support
Indications for Use
◆◆ Sudden
stressful event or
ongoing stress (internal
or external)
◆◆ Signs of fatigue, reduced
stamina, glucose intolerance,
inflammatory response, and
inadequate immune system
functioning
◆◆ Clinical signs associated with
adrenal stress
Adjunctive Products
◆◆ Canine
Whole Body Support
◆◆ Canine Hepatic Support
Supplement Facts
Ingredients
Bovine liver, bovine adrenal PMG™ extract, black currant juice, alfalfa juice,
porcine duodenum, Eleutherococcus senticosus, defatted wheat germ,
mushroom, nutritional yeast, carrot, wheat germ oil, veal bone PMG™
extract, buckwheat leaf juice and seed, bovine adrenal Cytosol™ extract,
pea vine juice, rice bran, bovine adrenal, bovine kidney, sea salt, oat flour,
bovine orchic extract, allantoin, bovine pituitary PMG™ extract, bovine
thyroid PMG™ extract, sunflower lecithin, chlorophyll extract, kelp, and
manganese glycerophosphate.
Minerals
Sodium. . . . . . 35 mg / ½ tsp.
Content
Product No.
Servings per Container
25 g. . . . . . . . A1100 . . . . . . . . . 65 based on 1⁄8 tsp.
100 g. . . . . . . A1150 . . . . . . . . . 65 based on ½ tsp.
Dose Schedule
Based on body weight, the canine patient should receive the formula
according to the following recommendations, or as otherwise directed.
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
29
Canine Formulas
Canine Cardiac Support
The heart is at the center of the cardiovascular system, which is a complex, coordinated group of organs
and tissues. Nutritional support for the cardiovascular system also includes the other organs that
support the heart such as the liver, kidneys, and digestive system.
Canine Cardiac Support provides nutrients that:
◆◆ Support
optimal cardiac function
◆◆ Support normal function of muscle-cells*
Indications for Use
◆◆ General
cardiac support
◆◆ Patients with increased
cardiac demand or conditions
that increase cardiac workload
Adjunctive Products
◆◆ Canine
Renal Support
◆◆ Canine Adrenal Support
Supplement Facts
Ingredients
L-carnitine, bovine liver, bovine heart PMG™ extract, rice bran, bovine
kidney, bovine and ovine spleen, bovine orchic extract, beet root, defatted
wheat germ, buckwheat leaf juice and seed, high selenium yeast,
ribonucleic acid, wheat germ oil, bovine pancreas Cytosol™ extract, veal
bone PMG™ extract, alfalfa juice, mushroom, calcium lactate, Crataegus
oxyacantha, nutritional yeast, carrot, pea vine juice, Tillandsia usneoides,
para‑aminobenzoate, chlorophyll extract, inositol, choline bitartrate, oat
flour, porcine brain, and ascorbic acid.
Minerals
Calcium. . . . . . 1 mg / ½ tsp.
Sodium. . . . . . 12 mg / ½ tsp.
Selenium. . . . . 18 mcg / ½ tsp.
Content
Product No.
25 g. . . . . . . . A1200 . . . . . . . . . 60 based on 1⁄8 tsp.
100 g. . . . . . . A1250 . . . . . . . . . 70 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
30
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
Nutrition plays a major role in skin health. Healthy skin is a result of a well-functioning, synchronized
effort by tissues and organs in the body.
Canine Dermal Support contains whole food ingredients to help:
◆◆ Maintain
◆◆ Support
proper liver, adrenal, immune, and intestinal function
and maintain the skin’s ability to withstand the effects of environmental exposures*
Indications for Use
◆◆ General
skin health
◆◆ General digestive system health,
adrenal gland health, or immune
system health
Adjunctive Products
◆◆ Canine
Enteric Support
◆◆ Canine Adrenal Support
◆◆ Canine Hepatic Support
Canine Formulas
Canine Dermal Support
Supplement Facts
Ingredients
Bovine liver, L-glutamine, Silybum marianum, bovine kidney, defatted
wheat germ, alfalfa juice, Emblica officinalis, carrot (root), fat soluble
extract (from alfalfa [whole plant], sunflower [seed], carrot [root], Tillandsia
usneoides, buckwheat [leaf and seed], and pea [vine]), bovine and
ovine spleen, bovine adrenal PMG™ extract, Perna canaliculus, calcium
lactate, bovine liver fat extract, black currant juice, Carthamus tinctorius,
bovine liver PMG™ extract, nutritional yeast, mushroom, porcine jejunum,
maltodextrin, porcine stomach, betaine hydrochloride, bovine parotid PMG™
extract, para-aminobenzoate, beet leaf juice, beet root, oat flour, porcine
brain, bovine adrenal Cytosol™ extract, purified bovine bile salts, bone
meal, Taraxacum officinale, and inositol.
Minerals
Zinc. . . . . . . . 58 mcg / ½ tsp.
Vitamins
Vitamin A. . . . . 12 IU / ½ tsp.
Content
Product No.
30 g. . . . . . . . A1300 . . . . . . . . . 65 based on 1⁄8 tsp.
125 g. . . . . . . A1350 . . . . . . . . . 75 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
31
Canine Formulas
Canine Enteric Support
A healthy digestive tract is critical to overall health and well-being. In addition to breakdown and
absorption of nutrients, digestive health can also have a significant impact on other body systems
(immune system, liver, bone marrow, or adrenal glands).
Canine Enteric Support contains a variety of functional foods, both plant and animal, that “feed” the
various components of the digestive system to:
◆◆ Provide
general digestive system support
◆◆ Support the ability of intestinal cells to function, regenerate, and respond to daily metabolic and
immune challenges*
Indications for Use
◆◆ General
enteric support
with increased
metabolic demand
◆◆ Hepatic patients in need of
additional enteric support
◆◆ Patients
Adjunctive Products
◆◆ Canine
◆◆ Canine
Immune System Support
Hepatic Support
Supplement Facts
Ingredients
Porcine stomach, L-glutamine, porcine duodenum, porcine jejunum,
bovine and ovine spleen, defatted wheat germ, bovine liver, veal bone
PMG™ extract, alfalfa juice, bovine parotid PMG™ extract, bovine kidney,
mushroom, nutritional yeast, bovine liver PMG™ extract, bovine adrenal
PMG™ extract, pea vine juice, bovine pancreas Cytosol™ extract, carrot,
rice bran, bovine orchic extract, oat flour, bovine pancreas PMG™ extract,
purified bovine bile salts, Tillandsia usneoides, licorice, allantoin, wheat
germ oil, beet leaf juice, beet root, calcium glycerophosphate, chlorophyll
extract, bovine pituitary PMG™ extract, bentonite, and bovine parathyroid.
Minerals
Phosphorus. . . 5 mg / ½ tsp.
Sodium. . . . . . 12 mg / ½ tsp.
Vitamins
Vitamin B2. . . . 30 mcg / ½ tsp.
Niacin. . . . . . . 0.2 mcg / ½ tsp.
Content
Product No.
30 g. . . . . . . . A1400 . . . . . . . . . 75 based on 1⁄8 tsp.
110 g. . . . . . . A1450 . . . . . . . . . 70 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
32
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
Wear and tear of joints and surrounding tissues, especially in very active and aging dogs, can cause
stiffness and trigger their body’s normal inflammatory response function.
Canine Flex Support helps maintain healthy joint function, including support for the cartilage.
It provides nutrients that:
Canine Formulas
Canine Flex Support
◆◆ Moderate
the body’s normal inflammatory response
potent antioxidants
◆◆ Support healthy immune modulation*
◆◆ Provide
Indications for Use
◆◆ Maintenance:
especially for large
breeds, performance dogs, and
growing puppies
◆◆ Short- or long-term support: for
any dog with joint challenges,
especially for active or
aging dogs
Adjunctive Product
◆◆ Canine
Musculoskeletal Support
Supplement Facts
Ingredients
Glucosamine (as glucosamine sulfate) (shellfish source) . . . . . 250 mg
Chondroitin (as chondroitin sulfate) (bovine source). . . . . . . . . 110 mg
Vitamin E (as mixed tocopherols) (sunflower) . . . . . . . . . . . . . 5 IU
Vitamin C (as ascorbic acid) . . . . . . . . . . . . . . . . . . . . . . . . . 5 mg
Other Ingredients
Honey, ginger root, bovine liver, maltodextrin, gum acacia, turmeric extract,
silicon dioxide, tapioca starch, and calcium stearate.
Content
Product No.
100 wafers . . . A1480 . . . . . . . . . 100 based on 1 wafer per serving
Dose Schedule
Based on body weight, the canine patient should receive the canine
formula according to the following recommendations, or as otherwise
directed.
1-25 lbs.. . . . . 1 wafer / day
26-50 lbs.. . . . 2 wafers / day
51-80 lbs.. . . . 3 wafers / day
> 80 lbs.. . . . . 4 wafers / day
33
Canine Formulas
Canine Hepatic Support
The liver is a complex organ that interacts with most organs in the body, including the intestinal tract,
cardiovascular system, kidneys, and autonomic nervous system. Nutritional support for the liver must
address these interactions to be effective.
Canine Hepatic Support is formulated to support:
◆◆ Liver
metabolism
◆◆ Hepatic circulation
Indications for Use
◆◆ General
hepatic support
metabolic demand
Adjunctive Products
◆◆ Canine
◆◆ Canine
Renal Support
Enteric Support
◆◆ Bile
production and flow
◆◆ Hepatic immune function*
Supplement Facts
Ingredients
Bovine liver PMG™ extract, bovine and ovine spleen, porcine duodenum,
bovine kidney, porcine stomach, veal bone PMG™ extract, porcine jejunum,
wheat germ oil, mushroom, bovine liver, bovine heart PMG™ extract,
bovine orchic extract, ribonucleic acid, alfalfa juice, defatted wheat germ,
calcium lactate, Ginkgo biloba, nutritional yeast, rice bran, black currant
seed oil, beet leaf juice, beet root, oat flour, Silybum marianum, Taraxacum
officinale, bovine liver fat extract, buckwheat leaf juice and seed, high
selenium yeast, calcium glycerophosphate, L-glutamine, zinc rice chelate,
Brussels sprouts, para-aminobenzoate, Perna canaliculus, carrot, Tillandsia
usneoides, bovine pituitary PMG™ extract, porcine brain, allantoin, bovine
thyroid PMG™ extract, magnesium lactate, betaine hydrochloride, inositol,
chlorophyll extract, choline bitartrate, and ascorbic acid.
Minerals
Calcium. . . . . . 2.5 mg / ½ tsp.
Magnesium . . . 800 mcg / ½ tsp.
Content
Product No.
30 g. . . . . . . . A1500 . . . . . . . . . 70 based on 1⁄8 tsp.
110 g. . . . . . . A1550 . . . . . . . . . 75 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
34
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
The immune system is a complex array of cells that are found throughout the body. Immune cells are
designed to work in conjunction with other cells to provide a defense against unwanted invaders. The
complexity of the immune system requires a multidimensional approach of nutritional factors. The
nutritional support of the immune system is directed at facilitating normal function and is not intended
to be suppressive or stimulating.
Canine Formulas
Canine Immune System Support
Canine Immune System Support:
◆◆ Provides
◆◆ Supports
nutritional and biochemical support for healthy immune cells and tissues
optimal immune system function*
Indications for Use
◆◆ General
climates or during the
fall/winter months
◆◆ When kenneled or in a shelter
◆◆ Colder
Adjunctive Products
◆◆ Canine
Hepatic Support
◆◆ Canine Enteric Support
Supplement Facts
Ingredients
Bovine liver, nutritional yeast, bovine and ovine spleen, rice bran, bovine
spleen PMG™ extract, bovine thymus PMG™ extract, carrot, bovine kidney,
bovine thymus Cytosol™ extract, buckwheat leaf juice and seed, bovine
pancreas Cytosol™ extract, pea vine juice, Eleutherococcus senticosus,
porcine duodenum, black currant juice, porcine jejunum, bovine adrenal
Cytosol™ extract, veal bone PMG™ extract, oat flour, calcium lactate,
purified bovine bile salts, defatted wheat germ, mushroom, Spanish black
radish, ribonucleic acid, bovine adrenal PMG™ extract, Tillandsia usneoides,
Withania somnifera, zinc rice chelate, kelp, and black currant seed oil.
Minerals
Calcium. . . . . . 2.5 mg / ½ tsp.
Sodium. . . . . . 25 mg / ½ tsp.
Magnesium. . . 700 mcg / ½ tsp.
Zinc. . . . . . . . 480 mcg / ½ tsp.
Content
Product No.
30 g. . . . . . . . A1600 . . . . . . . . . 75 based on 1⁄8 tsp.
110 g. . . . . . . A1650 . . . . . . . . . 75 based on ½ tsp.
Dose Schedule
according to the following recommendations, or as otherwise
directed.
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
35
Canine Formulas
Canine Musculoskeletal Support
The canine musculoskeletal system has many components: bones, joints, muscles, tendons,
ligaments, nerves, blood vessels, and organs that support these tissues, including the liver,
kidneys, and adrenal glands.
Canine Musculoskeletal Support:
◆◆ Provides
◆◆ Helps
a wide range of essential nutrients
maintain optimal health and function
Indications for Use
◆◆ General
growth support
animals
◆◆ Senior animals
◆◆ General musculoskeletal support
◆◆ Performance/working
Adjunctive Products
◆◆ Canine
Hepatic Support
◆◆ Canine Whole Body Support
Supplement Facts
Ingredients
Veal bone PMG™ extract, Boswellia serrata, bovine trachea,
Perna canaliculus, bovine heart PMG™ extract, pea vine juice, oat flour,
black currant juice, carrot, bovine liver, bovine adrenal, Eleutherococcus
senticosus, bovine orchic Cytosol™ extract, bovine kidney, sunflower
lecithin, bromelain, alfalfa juice, porcine jejunum, porcine duodenum,
beet root, manganese lactate, ribonucleic acid, bovine thyroid PMG™
extract, buckwheat leaf juice and seed, calcium lactate, beet root juice,
defatted wheat germ, wheat germ oil, Tillandsia usneoides, beet leaf
juice, mushroom, dicalcium phosphate, magnesium lactate, calcium
glycerophosphate, chlorophyll extract, and extract of Rhizopus oryzae
grown on Tillandsia usneoides and beet root.
Minerals
Sodium. . . . . . 17 mg / ½ tsp.
Magnesium. . . 900 mcg / ½ tsp.
Manganese. . . 700 mcg / ½ tsp.
Content
Product No.
20 g. . . . . . . . A1700 . . . . . . . . . 65 based on 1⁄8 tsp.
90 g. . . . . . . . A1750 . . . . . . . . . 78 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
36
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
For renal challenges, not only should the kidneys be supported but consideration should also be given to
support of the liver, cardiovascular system, and autonomic nervous system.
Canine Renal Support:
◆◆ Provides
support for the normal function of the kidneys
◆◆ Supports the liver, cardiovascular system, and nervous system*
Indications for Use
◆◆ Patients
in need of renal support
additional renal support
Adjunctive Products
◆◆ Canine
Hepatic Support
◆◆ Canine Cardiac Support
Canine Formulas
Canine Renal Support
Supplement Facts
Ingredients
Bovine kidney, kidney bean extract, buckwheat leaf juice and seed, oat
flour, bovine liver, ribonucleic acid, nutritional yeast, veal bone PMG™
extract, bovine orchic Cytosol™ extract, pea vine juice, beet root, bovine
and ovine spleen, alfalfa juice, bovine kidney PMG™ extract, mushroom,
rice bran, bovine thyroid PMG™ extract, carrot, wheat germ oil, black
currant seed oil, black currant juice, kelp, bovine adrenal, allantoin, bovine
pituitary PMG™ extract, chlorophyll extract, manganese glycerophosphate,
beet leaf juice, and extract of Rhizopus oryzae grown on Tillandsia
usneoides and beet root.
Minerals
Sodium. . . . . . 60 mg / ½ tsp.
Chloride. . . . . 10 mg / ½ tsp.
Content
Product No.
30 g. . . . . . . . A1800 . . . . . . . . . 70 based on 1⁄8 tsp.
110 g. . . . . . . A1850 . . . . . . . . . 75 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
37
Canine Formulas
Canine Thyroid Support
The endocrine system has an interesting web of interactions with different organs in the body, and the
thyroid gland plays a major role.
Canine Thyroid Support:
◆◆ Provides
critical trace mineral support for the thyroid gland
◆◆ Supports glands and tissues that interact with the thyroid, including the adrenals and liver
◆◆ Supports all aspects of thyroid function*
Indications for Use
◆◆ General
thyroid support
metabolic demand
Adjunctive Products
◆◆ Canine
◆◆ Canine
Whole Body Support
Hepatic Support
Supplement Facts
Ingredients
Eleutherococcus senticosus, bovine liver, bovine orchic extract, bovine
adrenal, bovine thyroid PMG™ extract (processed to remove its thyroxine),
Tillandsia usneoides, mushroom, buckwheat leaf juice and seed, calcium
lactate, Perna canaliculus, carrot, bovine adrenal PMG™ extract, sunflower
lecithin, porcine ovary PMG™ extract, kelp, wheat germ oil, rice bran,
bone meal, pea vine juice, defatted wheat germ, alfalfa juice, bovine
heart PMG™ extract, porcine duodenum, para-aminobenzoate, oat flour,
ribonucleic acid, porcine brain, calcium glycerophosphate, and
ascorbic acid.
Minerals
Calcium. . . . . . 8 mg / ½ tsp.
Phosphorus. . . 5 mg / ½ tsp.
Sodium. . . . . . 25 mg / ½ tsp.
Content
Product No.
25 g. . . . . . . . A1900 . . . . . . . . . 65 based on 1⁄8 tsp.
100 g. . . . . . . A1950 . . . . . . . . . 80 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
38
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
Supplements made from whole foods, organ and tissue extracts, botanicals, and other ingredients can fill
nutrition gaps.
Canine Whole Body Support:
◆◆ Provides
general multisystem support for daily maintenance of all body systems, with emphasis on a
healthy endocrine system
◆◆ Is an excellent nutritional foundation for use with all other system-support formulas*
Indications for Use
◆◆ Daily
supplement for any patient
◆◆ Growing animals
◆◆ Performance/working animals
◆◆ Endocrine system support
Adjunctive Products
◆◆ Canine
Hepatic Support
◆◆ Canine Immune System Support
◆◆ Canine Renal Support
◆◆ Canine Cardiac Support
Canine Formulas
Canine Whole Body Support
Supplement Facts
Ingredients
Defatted wheat germ, bovine liver, pea vine juice, nutritional yeast, carrot,
rice bran, bovine and ovine spleen, alfalfa juice, Silybum marianum, beet
root, porcine stomach, oat flour, bovine heart PMG™ extract, Tillandsia
usneoides, L-carnitine, Brussels sprouts, bovine orchic Cytosol™ extract,
kidney bean extract, kelp, bovine liver PMG™ extract, bone meal, bovine
trachea, bovine kidney PMG™ extract, mushroom, bovine kidney, inositol,
choline bitartrate, thiamine hydrochloride, bovine adrenal Cytosol™ extract,
celery, bentonite, veal bone PMG™ extract, bovine liver fat extract, calcium
lactate, manganese glycerophosphate, carbamide, bovine adrenal PMG™
extract, bovine hypothalamus Cytosol™ extract, bovine thymus PMG™
extract, bovine pituitary PMG™ extract, zinc rice chelate, copper rice
chelate, iron rice chelate, sunflower lecithin, bovine hypothalamus PMG™
extract, bovine thymus Cytosol™ extract, bovine thyroid PMG™ extract,
para-aminobenzoate, porcine brain, and ascorbic acid.
Minerals
Calcium. . . . . . 5 mg / ½ tsp.
Sodium. . . . . . 14 mg / ½ tsp.
Iron . . . . . . . . 500 mcg / ½ tsp.
Copper. . . . . . . 200 mcg / ½ tsp.
Manganese. . . . 600 mcg / ½ tsp.
Zinc . . . . . . . . 300 mcg / ½ tsp.
Content
Product No.
25 g. . . . . . . . A2000 . . . . . . . . . 65 based on 1⁄8 tsp.
100 g. . . . . . . A2050 . . . . . . . . . 70 based on ½ tsp.
Dose Schedule
1-10 lbs.. . . . . 1⁄8 tsp. once / day
11-20 lbs.. . . . 1⁄8 tsp. twice / day
21-40 lbs.. . . . ¼ tsp. twice / day
41-60 lbs.. . . . ½ tsp. twice / day
61-80 lbs.. . . . ¾ tsp. twice / day
> 80 lbs.. . . . . 1 tsp. twice / day
39
Feline Formulas
Feline Formulas
Since cats are obligate carnivores, the feline formulas contain fewer ingredients than the
canine formulas and focus more on animal tissues. These ingredient combinations provide a
wide range of nutrients to support multiple organs. The feline formulas are in tablet form to
allow for several administration options.
40
The heart is at the center of the cardiovascular system, which is a complex, coordinated group of organs
and tissues. Nutritional support to the cardiovascular system also includes the organs that support the
heart, such as the liver, kidneys, and digestive system.
Feline Cardiac Support:
◆◆ Provides
◆◆ Supports
nutrients that support optimal cardiac function
normal function of muscle-cells*
Indications for Use
◆◆ General
cardiac support
cardiac demand or conditions
that increase cardiac workload
Adjunctive Products
◆◆ Feline
Renal Support
Hepatic Support
◆◆ Feline Whole Body Support
◆◆ Feline
Feline Formulas
Feline Cardiac Support
Supplement Facts
Ingredients
Bovine heart PMG™ extract, bovine orchic Cytosol™ extract, bovine
adrenal, bovine liver, Tillandsia usneoides, alfalfa juice, bovine and
ovine spleen, L-carnitine, buckwheat leaf juice and seed, bovine kidney,
Emblica officinalis, rice bran, pea vine juice, nutritional yeast, Crataegus
oxyacantha, ribonucleic acid, kelp, bovine adrenal Cytosol™ extract, wheat
germ oil, oat flour, and bone meal.
Other Ingredients
Honey and calcium stearate as tableting aids.
Minerals
Calcium. . . . . . 1 mg / tablet
Potassium. . . . 5 mg / tablet
Sodium. . . . . . 3 mg / tablet
Manganese. . . 3.5 mcg / tablet
Content
Product No.
90 tablets . . . . A5005
How to Administer
The feline patient should receive one tablet two times per day,
or as directed. Feline formulas can be administered in a variety of
ways, including:
◆◆ Whole
tablet or crushed
◆◆ Dosed directly or mixed with food
◆◆ Cautiously, as a powder suspended in water given by oral syringe
To familiarize the cat with the supplement, it may be helpful to place
one tablet beside the food bowl for two or three days prior to mixing
the tablet with the food.
41
Feline Formulas
Feline Enteric Support
A healthy digestive tract is critical to overall health and well-being. The digestive health of an animal
can impact not only breakdown and absorption of nutrients, but can also have a significant impact on
other body systems (immune system, liver, bone marrow, or adrenal glands).
Feline Enteric Support contains a variety of functional foods, both plant and animal, that “feed” the
various components of the digestive system to:
◆◆ Provide
general digestive system support
◆◆ Support the ability of intestinal cells to function, regenerate, and respond to daily metabolic and
immune challenges*
Indications for Use
◆◆ General
Supplement Facts
Adjunctive Products
Ingredients
Bovine and ovine spleen, porcine jejunum, bovine liver, porcine stomach,
L-glutamine, porcine duodenum, rice bran, nutritional yeast, bovine kidney,
defatted wheat germ, alfalfa juice, Perna canaliculus, carrot, allantoin, veal
bone PMG™ extract, and chlorophyll extract.
enteric support
metabolic demand
additional enteric support
◆◆ Feline
◆◆ Feline Hepatic Support
Other Ingredients
Minerals
Manganese. . . 3.5 mcg / tablet
Content
Product No.
90 tablets . . . . A5105
How to Administer
ways, including:
◆◆ Whole
tablet or crushed
directly or mixed with food
◆◆ Dosed
To familiarize the cat with the supplement, it may be helpful to place one
tablet beside the food bowl for two or three days prior to mixing the tablet
with the food.
42
The liver is a complex organ that interacts with most organs in the body, including the intestinal tract,
cardiovascular system, kidneys, and autonomic nervous system. Nutritional support for the liver must
address these interactions to be effective.
Feline Hepatic Support is formulated to support:
Feline Formulas
Feline Hepatic Support
◆◆ Liver
metabolism
circulation, bile production and flow
◆◆ Hepatic immune function*
◆◆ Hepatic
Indications for Use
◆◆ General
hepatic support
metabolic demand
Adjunctive Products
◆◆ Feline
Renal Support
Enteric Support
◆◆ Feline
Supplement Facts
Ingredients
Bovine liver PMG™ extract, bovine liver, bovine and ovine spleen, bovine
kidney, L-glutamine, Emblica officinalis, porcine stomach, bone meal,
pea vine juice, porcine duodenum, buckwheat leaf juice and seed, Perna
canaliculus, oat flour, bovine kidney PMG™ extract, defatted wheat
germ, nutritional yeast, bovine liver fat extract, bovine adrenal, Silybum
marianum, beet leaf juice, beet root, inositol, choline bitartrate, alfalfa
juice, rice bran, copper rice chelate, zinc rice chelate, iron rice chelate, and
extract of Rhizopus oryzae grown on Tillandsia usneoides and beet root.
Other Ingredients
Minerals
Chloride. . . . . 7 mg / tablet
Iron . . . . . . . . 150 mcg / tablet
Copper . . . . . . 15 mcg / tablet
Zinc. . . . . . . . 21 mcg / tablet
Content
Product No.
90 tablets. . . . A5205
How to Administer
ways, including:
◆◆ Whole
tablet or crushed
◆◆ Dosed directly or mixed with food
with the food.
43
Feline Formulas
Feline Immune System Support
The immune system is a complex array of cells that are found throughout the body. Immune cells are
designed to work in conjunction with each other to provide a defense against unwanted invaders. The
complexity of the immune system requires a multidimensional approach to nutritional factors.
Nutritional support of the immune system is directed at facilitating normal function and is not intended
to be suppressive or stimulating.
Feline Immune System Support:
◆◆ Provides
◆◆ Supports
nutritional and biochemical support for healthy immune cells and tissues
optimal immune system function*
Indications for Use
◆◆ General
◆◆ Colder climates or during the
fall/winter months
◆◆ When kenneled or in a shelter
Adjunctive Products
◆◆ Feline
◆◆ Feline
Whole Body Support
Enteric Support
Supplement Facts
Ingredients
Eleutherococcus senticosus, bovine liver, L-glutamine, porcine jejunum,
bovine orchic Cytosol™ extract, Emblica officinalis, ribonucleic acid, bovine
and ovine spleen, bovine spleen PMG™ extract, bovine thymus Cytosol™
extract, bovine pituitary PMG™ extract, bovine adrenal Cytosol™ extract,
buckwheat leaf juice and seed, pea vine juice, bovine hypothalamus Cytosol™
extract, oat flour, bovine kidney, bovine thyroid PMG™ extract, alfalfa juice,
copper rice chelate, iron rice chelate, zinc rice chelate, kelp, and bovine
pancreas PMG™ extract.
Other Ingredients
Minerals
Potassium. . . . 3.5 mg / tablet
Iron . . . . . . . . 140 mcg / tablet
Copper . . . . . . 20 mcg / tablet
Zinc. . . . . . . . 70 mcg / tablet
Content
Product No.
90 tablets . . . . A5305
How to Administer
ways, including:
◆◆ Whole
tablet or crushed
◆◆ Dosed
with the food.
44
For renal challenges, not only should the kidneys be supported but consideration should also be given to
support of the liver, cardiovascular system, and autonomic nervous system.
Feline Renal Support:
Feline Formulas
Feline Renal Support
◆◆ Facilitates
support and natural rehabilitation of the kidneys
◆◆ Provides balanced cellular nutrition for all aspects of urinary system function*
Indications for Use
◆◆ Patients
in need of renal support
additional renal support
Adjunctive Products
◆◆ Feline
Hepatic Support
◆◆ Feline Cardiac Support
Supplement Facts
Ingredients
Bovine kidney PMG™ extract, bovine kidney, bovine liver, veal bone
PMG™ extract, bone meal, defatted wheat germ, bovine and ovine spleen,
buckwheat leaf juice and seed, Emblica officinalis, oat flour, pea vine juice,
bovine adrenal Cytosol™ extract, ribonucleic acid, alfalfa juice, bovine heart
PMG™ extract, kidney bean extract, Perna canaliculus, Tillandsia usneoides,
rice bran, porcine duodenum, beet leaf juice, beet root, and extract of
Rhizopus oryzae grown on Tillandsia usneoides and beet root.
Other Ingredients
Minerals
Calcium. . . . . . 3.5 mg / tablet
Phosphorus. . . 2.4 mg / tablet
Content
Product No.
90 tablets . . . . A5405
How to Administer
ways, including:
◆◆ Whole
tablet or crushed
◆◆ Dosed
one tablet beside the food bowl for two or three days prior to mixing the
tablet with the food.
45
Feline Formulas
Feline Whole Body Support
Supplements made with whole food ingredients, organ and tissue extracts, botanicals, and other
ingredients can fill nutrition gaps.
Feline Whole Body Support:
◆◆ Provides
general multisystem support for daily maintenance of all body systems with emphasis on a
healthy endocrine system
◆◆ Is an excellent nutritional foundation for use with all other system-support formulas*
Indications for Use
◆◆ Daily
supplement for any patient
animals
◆◆ Active animals
◆◆ Endocrine system support
◆◆ Growing
Adjunctive Products
◆◆ Feline
Hepatic Support
Enteric Support
◆◆ Feline Renal Support
◆◆ Feline
Supplement Facts
Ingredients
Bovine liver, bovine and ovine spleen, alfalfa juice, bovine liver PMG™
extract, bovine trachea, bone meal, bovine heart PMG™ extract,
L-glutamine, bovine kidney, rice bran, porcine jejunum, Emblica officinalis,
bovine kidney PMG™ extract, buckwheat leaf juice and seed, oat flour,
bovine adrenal Cytosol™ extract, nutritional yeast, pea vine juice, bovine
orchic Cytosol™ extract, high chromium yeast, Perna canaliculus, beet leaf
juice, beet root, zinc rice chelate, L-carnitine, maltodextrin, defatted wheat
germ, kidney bean extract, inositol, allantoin, choline bitartrate, and extract
of Rhizopus oryzae grown on Tillandsia usneoides and beet root.
Other Ingredients
Minerals
Zinc. . . . . . . . 180 mcg / tablet
Chromium. . . . 5 mcg / tablet
Content
Product No.
90 tablets . . . . A5505
How to Administer
ways, including:
◆◆ Whole
tablet or crushed
◆◆ Dosed
one tablet beside the food bowl for two or three days prior to mixing the
tablet with the food.
46
Equine Formulas
Equine Formulas
The equine formulas contain ingredients such as vegetables, herbs, and fruits to deliver a
full spectrum of phytonutrients, enzymes, minerals, and vitamins in their most potent form.
Safe and effective, these formulas were developed to target the nutritional demands of
specific systems. The equine formulas are in powder form and do not contain any animal
tissues. Each formula can be used for either short- or long-term support.
47
Equine Formulas
Equine GI Support
Product Overview
The equine gastrointestinal (GI) tract is an
extensive set of organs that must function as a
synergistic team to maintain: healthy intestinal
function, a healthy stomach lining, a normal
appetite, a cooperative working attitude, and a
pleasant disposition.
Equine GI Support is backed by research-proven
ingredients that support:
◆◆ Liver
detoxification pathways
◆◆ Lining of the stomach
◆◆ Healthy bacterial populations in the intestine
◆◆ Energy generation
◆◆ Oxidation processes*
Equine GI Support can be added to a balanced
equine diet to ensure smooth operation of
the horse’s:
◆◆ Upper
GI tract
gut
◆◆ Immune system*
◆◆ Hind
Supplement Facts
Product Number
E7700
Content
30 ounces (850 g)
Serving Size
¼ cup (30 g)
Servings Per Container
28
Ingredients
Whey (milk) protein powder, flax meal, L-glutamine,
inulin, rice protein powder, Brussels sprouts (whole
plant), kale (whole plant), corn starch, calcium citrate,
magnesium citrate, buckwheat (leaf), choline bitartrate,
inositol, chamomile extract, alfalfa (whole plant) juice
powder, gum acacia, grape (seed) extract, sunflower
lecithin powder, vitamin E (sunflower), carrot (root)
powder, and red wine extract.
Suggested Use
¼ cup (30 g)/1,000 lb. horse/day, or as directed.
Warnings
For equine use only. Keep all supplements out of
the reach of children and other animals. In case of
accidental overdose, contact a health care
professional immediately.
Precautions
Safe use in pregnant animals or animals for breeding
has not been proven.
48
Brussels sprouts and kale: Cruciferous vegetables like
Brussels sprouts and kale influence detoxification pathways.
These vegetables contain compounds called glucosinolates and
an enzyme called myrosinase. When crucifers are cut or chewed,
myrosinase enzymes act on the glucosinolates to make them
into other compounds that have demonstrated (via cell, animal,
and epidemiological studies) an increase in the activation of
detoxification enzymes.1, 2
Equine Formulas
Key Ingredients
Chamomile: This well-known herb has a long history of
traditional use as support for the stomach lining, complete
digestive system, and immune system balance. Chamomile is
also thought to act as a natural calmative that relaxes while still
maintaining a positive energy level. Equine GI Support contains
chamomile that is standardized to contain 1.2 percent apigenin, a
key flavonoid linked to a number of health effects in animal
studies.3, 4 This ingredient could be considered a controlled substance by certain entities that govern equine competitions.
We advise those who feed any supplement to competing horses to check with the governing body specific to the event regarding
whether the product contains ingredients that could be considered a controlled substance.
Inulin: This nondigestible fiber supports the cecum in horses.
Levels of up to 2 percent in feed improved fermentation in the
cecum without any adverse effects. In humans, inulin shows
preferential support for Bifidobacteria populations, while
promoting healthy bacteria and pH in the gut. Inulin also
supports immune-cell function and antibody production in the
gut, absorption of calcium and magnesium, and healthy
elimination. 5, 6, 7, 8
L-glutamine: Glutamine is an amino acid that is used as a
building block for other amino acids and compounds like
glutathione. Some of our cells that require a lot of energy (like those in the gut) can use glutamine as
an energy source. In this way, glutamine supports the integrity of the intestinal lining and the immune
cells associated with the intestines. This amino acid can be depleted by stress, which can in turn slow
the body’s natural regeneration and healing process.9, 10
Vitamin E: This fat-soluble vitamin has antioxidant properties that support the body under stress.
Stress is often associated with an increase in oxidation products that could damage cells.
See equine feeding tips on page 57.
1.Robbins MG, Andersen G, Somoza V, Eshelman BD, Barnes DM, Hanlon PR. Heat treatment of Brussels sprouts retains their ability to induce detoxification enzyme expression in vitro and in vivo.
J Food Sci. 2011 Apr; 76(3):C454-61.
2.Robbins MG, Hauder J, Somoza V, Eshelman BD, Barnes DM, Hanlon PR. Induction of detoxification enzymes by feeding unblanched Brussels sprouts containing active myrosinase to mice for 2 wk.
J Food Sci. 2010 Aug 1;75(6):H190-9.
3.Gupta SC, Kim JH, Prasad S, Aggarwal BB. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals.
Cancer Metastasis Rev. 2010 Sep; 29(3):405-34.
4.Amsterdam JD, et al. A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. J Clin Psychopharmacol. 2009;
29(4):378-82.
5.Van Loo J. How chicory fructans contribute to zootechnical performance and well-being in livestock and companion animals. J. Nutr. 2007; 137(11): 2594S-2597.
6.Kleessen B, Schwarz S, Boehm A, Fuhrmann H, Richter A, Henle T, Krueger M. Jerusalem artichoke and chicory inulin in bakery products affect faecal microbiota of healthy volunteers. Br J Nutr. 2007
Sep; 98(3):540-9. Epub 2007 Apr 20.
7.Watzl B., Girrbach S., and Roller M. Inulin, oligofructose and immunomodulation. Br J Nutr. 2005; 93 Suppl 1: p. S49-55.
8.Scholz-Ahrens K.E., et al., Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. J Nutr, 2007. 137(3 Suppl 2): p. 838S-46S.
9.Ehrlich SD. (2009, June 20) Complementary medicines. Glutamine. July 29, 2011; http://www.umm.edu/altmed/articles/glutamine-000307.htm.
10.Lacey JM and Wilmore DW. Is glutamine a conditionally essential amino acid? Nutrition Reviews.2009; 48(8): 297-309.
49
Equine Formulas
Equine Immune Support
Product Overview
The equine immune system faces countless
stressors year-round. Training, competition,
travel, environmental factors, and lack of turnout
can all take a toll.
Equine Immune Support is a complex
supplement for a complex system, caring for the
interlocking cells and organisms that coordinate
activity to recognize what belongs in the body and
what doesn’t. Equine Immune Support encourages
an optimal immune response—either defensive or
offensive—to safeguard the health, performance,
and stamina of the horse by supporting:
◆◆ Immune-cell
signaling
activities
◆◆ Cell integrity
◆◆ Nutritional status*
◆◆ Antioxidant
This supplement is uniquely designed with whole
food and other ingredients to:
◆◆ Support
the entire body while targeting vital
aspects of immune system response
◆◆ Help the body respond in the most appropriate
way in times of need, whether that is by
stimulating or calming the normal, healthy
immune response*
Key Ingredients
L-glutamine: This amino acid is a universal
energy substrate for cells throughout the
body, especially those of the immune system.
Glutamine’s broad role in metabolism supports
the body’s natural regeneration and
healing processes.1, 2
Supplement Facts
Product Number
E7800
Content
30 ounces (850 g)
Serving Size
¼ cup (30 g)
28
Ingredients
turmeric (root) extract, maltodextrin, rice protein
powder, mushroom powder (Coriolus versicolor),
mushroom powder (reishi/shiitake), yeast culture,
calcium citrate, magnesium citrate, buckwheat (leaf),
Brussels sprouts (whole plant), kale (whole plant),
choline bitartrate, inositol, alfalfa (whole plant) juice
powder, grape (seed) extract, sunflower lecithin
powder, arabic gum, starch, sucrose (beets), carrot
(root), vitamin A palmitate, cholecalciferol, and red
wine extract.
Suggested Use
Warnings
Precautions
Turmeric: In-vitro and animal studies have
shown that curcumin, just one of many
phytochemicals in turmeric, supports the
downregulation of inflammatory cytokines,
displays antioxidant properties, and modulates a
wide range of cell-signaling molecules.3, 4, 5
50
◆◆ Turkey
tail mushroom’s support for immune
function is mainly attributed to a protein-bound
polysaccharide and has been shown to support the
antibody-mediated immune response.6
◆◆ Shiitake has a long history of traditional use for
immune stimulation, cholesterol processing, and
overall support for aging.7, 8
◆◆ Reishi is traditionally used to support
cholesterol already within a normal range,
blood flow, stamina, and antibody-mediated
immune response.9, 10, 11, 12
Equine Formulas
Mushrooms: Shiitake (Lentinula edodes), reishi
(Ganoderma lucidum), and turkey tail (Coriolus
versicolor) mushrooms have a long history of use for
immune support in traditional Chinese medicine.
Vitamin A palmitate: This vitamin is critical for
maintaining epithelial-cell integrity, eye health, and
kidney and immune function. Vitamin A palmitate is
included in Equine Immune for support of epithelial
tissue—a front-line barrier in immune response.13
Vitamin D: Receptors for vitamin D are in almost
every immune cell, and current research suggests
that vitamin D helps regulate T cells, leading to
moderation of the normal inflammatory process.
Horses that are kept indoors or get limited sun
exposure might not have the opportunity to make
sufficient endogenous vitamin D.14
Yeast culture: Yeast cultures have more than
60 years of use in supporting immune status in
animals, including livestock, poultry, dogs, and cats.
Research in horses suggests that the addition of yeast
cultures supports a healthy gut environment and
nutrient availability.15, 16, 17
1.Ehrlich, SD. (2009, June 20) Complementary medicines. Glutamine. July 29, 2011; http://www.umm.edu/altmed/articles/glutamine-000307.htm.
2.Lacey, JM., Wilmore, DW. Is glutamine a conditionally essential amino acid? Nutrition Reviews 2009; 48(8): 297-309.
3.Nandal S, Dhir A, Kuhad A, Sharma S, Chopra K. Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model. Methods Find Exp Clin
Pharmacol. 2009 Mar;31(2):89-93.
4.Kolodziejczyk J, Olas B, Saluk-Juszczak J, Wachowicz B. Platelets. Antioxidative properties of curcumin in the protection of blood platelets against oxidative stress in vitro. 2011; 22(4):270-6. Epub 2011 Feb 8.
5.Chainani-Wu N. Safety and anti-inflammatory activity of curcumin: a component of turmeric (Curcuma longa). J Altern Complement Med. 2003; 9(1):161-8.
6.Jeong SC, Yang BK, GN K, et al. Macrophage-stimulating activity of polysaccharides extracted from fruiting bodies of Coriolus versicolor (Turkey Tail Mushroom). J Med Food. 2006;9:175-181.
7.Hobbs C. Medicinal Mushrooms, 3rd ed. Loveland (CO): Interweave Press; 1996.
8.Darmadi I, et al. Food and nutrient intakes and overall survival of elderly Japanese. Asia Pacific J Clin Nutr 2000; 9(1):7-11.
9.Kim SD. Isolation and structure determination of a cholesterol esterase inhibitor from Ganoderma lucidum. J Microbiol Biotechnol. 2010 Nov.; 20(11):1521-3.
10.Kumaran S, Palani P, Nishanthi R, Kaviyarasan V. Studies on screening, insolation and purification of a fibrinolytic protease from an isolate (VK12) of Ganoderma lucidum and evaluation of its
antithrombotic activity. Med Mycol J. 2011; 52(2):153-62.
11.Shiao MS.; Lee, KR.; Lin, LJ., Wang, CT. (1994) Natural products and biological activities of the Chinese medical fungus, Ganoderma lucidum, in: Food Phytochemicals for Cancer Prevention. II:
Teas, Spices and Herbs, (Ho, CT., Osawa, T., Huang, M.T. and Rosen, R.T.; Eds.), American Chemical Society: Washington, DC, p. 342-354.
12.Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov; 25(11):1387-95.
13.Semba RD. Impact of vitamin A on immunity and infection in developing countries. In: Bendich A, Decklebaum RJ, eds. Preventitive Nutrition: The Comprehensive Guide for Health Professionals.
2nd ed. Totowa: Humana Press Inc; 2001:329-346.
14.Marques CD, Dantas AT, Fragoso TS, Duarte AL. The importance of vitamin D levels in autoimmune diseases. [Article in English, Portuguese] Rev Bras Reumatol. 2010 Feb; 50(1):67-80.
15.Agazzi A, et al. Evaluation of the effects of live yeast supplementation on apparent digestibility of high-fiber diet in mature horses using the acid insoluble ash marker modified method. J of Equine Vet Sci.
2011; 31(1):13-18.
16.Jouany JP, Gobert J, Medina B, Bertin G, and Julliand V. Effect of live yeast culture supplementation on apparent digestibility and rate of passage in horses fed a high-fiber or high-starch diet. Journal of
Animal Science 2008; 86: 339-347.
17.Médina B, Girard ID., Jacotot E, Julliand V. Effect of a preparation of Saccharomyces cerevisiae on microbial profiles and fermentation patterns in the large intestine of horses fed a high fiber or a high starch
diet. Journal of Animal Science 2002; 80: 2600-2609.
51
Equine Formulas
Equine Metabolic Support
Product Overview
The metabolic system is complex, involving
organs such as the thyroid, liver, kidneys, and
pancreas. Some signs indicative of metabolic
stress may include:
◆◆ Changes
in insulin levels
◆◆ Seasonal pasture sensitivities
◆◆ Immune system challenges
◆◆ Excess weight or fatty deposits
Supplement Facts
Product Number
E7900
Content
40 ounces (1134 g)
Serving Size
¼ cup (37 g)
30
Equine Metabolic Support:
◆◆ Promotes
healthy glucose metabolism
and insulin function
◆◆ Provides antioxidant activity
◆◆ Supports the endocrine system*
Key Ingredients
Licorice root: There is evidence that licorice root
can help maintain glucose homeostasis as well as
pituitary hormone homeostasis.1 Licorice may
directly impact the underlying pituitary imbalance.
Cinnamon: There is evidence that components of
cinnamon can modulate glucose homeostasis.2-13
By maintaining normal glucose levels, it may be
possible to bring other endocrine signals back
to normal.
Ingredients
Buckwheat flour, carrot powder, cinnamon, licorice
(root), green tea extract, cayenne, chromium yeast,
and vanadium chelate (rice and soy).
Suggested Use
Warnings
For equine use only. Do not administer to cattle or
other ruminants. Keep all supplements out of the
reach of children and other animals. In case of
Precautions
Cayenne (chili powder): As with cinnamon, there is increasing evidence that chili powder can help
maintain normal glucose levels. The mechanism is unclear. Regular consumption of chili may attenuate
postprandial hyperinsulinemia.5, 7 This ingredient could be considered a controlled substance by certain entities that govern equine competitions. We advise those who feed any
supplement to competing horses to check with the governing body specific to the event regarding whether the product contains ingredients that could be considered a controlled substance.
Buckwheat flour: Buckwheat seed and juice contain a variety of flavonoids including rutin. Flavonoids
are primarily found conjugated to sugar molecules. In this form there is evidence that they can compete
with other sugars for uptake into the body. This might effectively slow the absorption of sugar and lessen
the postprandial glucose surge. This would lessen the concomitant insulin spike. In addition, rutin has
been implicated in the maintenance of capillary integrity and, along with the other flavonoids, provides
antioxidant activity.14-19
Green tea extract: Contains catechins/polyphenols that may work in a similar fashion as the flavonoids
found in buckwheat. Additionally, catechins/polyphenols have strong antioxidant properties and interact
with a number of signaling pathways related to immune system response.
Chromium: Potentiates insulin actions and combines with several other components to make the
glucose tolerance factor.20-26
Vanadium: Can mimic insulin’s actions. It is possible that by slowing glucose metabolism, improving
blood glucose levels, and mimicking insulin’s actions, circulating levels in a horse with metabolic
challenges may be reduced.27-34
52
Figure 1: Average serum level and corresponding blood glucose
Twenty-nine horses were identified with
elevated insulin, which can be associated
with challenges to the metabolic system.
Four veterinarians participated in the
evaluations and recommended ¼ cup of
Equine Metabolic Support daily for
four months.
Equine Formulas
Clinical Evaluations
Results
The response in fasting insulin levels
varied but predominantly decreased (20
animals). Figure 1 shows the average
serum insulin level and corresponding blood glucose levels over the course of the trial for all animals.
Even though blood glucose levels rose slightly, they still remained within the normal range for a horse.
1.Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice. Acta Diabetol.Lat. 1989;26(1):51-55.
2.Huss U, Ringbom T, Perera P, Bohlin L, Vasange M. Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay. J Nat Prod. 2002;65(11):1517-1521.
3.Reddy AM, Seo JH, Ryu SY, Kim YS, Kim YS, Min KR, Kim Y. Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. Planta Med 2004;70(9):823-827.
4.Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr 2003;133(5):1286-1290.
5.Shobana S, Naidu KA. Antioxidant activity of selected Indian spices. Prostaglandins Leukot. Essent. Fatty Acids 2000;62(2):107-110.
6.Berrio LF, Polansky MM, Anderson RA. Insulin activity: stimulatory effects of cinnamon and brewer’s yeast as influenced by albumin. Horm.Res 1992;37(6):225-229.
7.Broadhurst CL, Polansky MM, Anderson RA. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric.Food Chem 2000;48(3):849-852.
8.Imparl-Radosevich J, Deas S, Polansky MM, Baedke DA, Ingebritsen TS, Anderson RA, Graves DJ. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon
regulation of insulin signalling. Horm.Res 1998;50(3):177-182.
9.Jarvill-Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll.Nutr 2001;20(4):327-336.
10.Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84(1):105-108.
11.Kreydiyyeh SI, Usta J, Copti R. Effect of cinnamon, clove and some of their constituents on the Na(+)-K(+)-ATPase activity and alanine absorption in the rat jejunum. Food Chem Toxicol 2000;38(9):755-762.
12.Lee HS. Inhibitory activity of Cinnamomum cassia bark-derived component against rat lens aldose reductase. J Pharm Sci 2002;5(3):226-230.
13.Onderoglu S, Sozer S, Erbil KM, Ortac R, Lermioglu F. The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats. J.Pharm.Pharmacol.
1999;51(11):1305-1312.
14.Boyle SP, Dobson VL, Duthie SJ, et al. Bioavailability and efficiency of rutin as an antioxidant: a human supplementation study. Eur J Clin Nutr 2000;54(10):774-782.
15.Mathiesen FR. Arterial insufficiency in the leg treated with rutosides. A double blind trial. Vasa 1974;3(3):319-324.
16.Riabokon’ EN, Gavrilenko TI, Kornilina EM, et al. [The effect of Wobenzym on the atherogenic potential and inflammatory factors at the rehabilitation stage for patients who have had a myocardial infarct]. Lik
Sprava 2000;(5):111-114.
17.Ihme N, Kiesewetter H, Jung F, et al. Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: a single-centre, randomised, double-blind, placebo-controlled clinical trial.
Eur J Clin Pharmacol 1996;50(6):443-447.
18.Ortolani O, Conti A, De Gaudio AR, et al. Protective effects of N-acetylcysteine and rutin on the lipid peroxidation of the lung epithelium during the adult respiratory distress syndrome. Shock 2000;13(1):14-18.
19.Mayer B, Schumacher M, Brandstatter H, et al. High-throughput fluorescence screening of antioxidative capacity in human serum. Anal Biochem 2001;297(2):144-153.
20.Anderson RA. Chromium in the prevention and control of diabetes. Diabetes Metab 2000;26(1):22-27.
21.Bahijri SM, Mufti AM. Beneficial effects of chromium in people with type 2 diabetes, and urinary chromium response to glucose load as a possible indicator of status. Biol Trace Elem Res 2002;85(2):97-109.
22.Balk EM, Tatsioni A, Lichtenstein AH, Lau J, Pittas AG. Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials. Diabetes Care. 2007
Aug;30(8):2154-63. Epub 2007 May 22.
23.Hoeger WW, Harris C, Long EM, Hopkins DR. Four-week supplementation with a natural dietary compound produces favorable changes in body composition. Adv Ther. 1998 Sep-Oct;15(5):305-14.
24.Jovanovic L, Gutierrez M, Peterson CM. Chromium supplementation for women with gestational diabetes mellitus. J Trace Elem Exp Med 1999;12(2):91-97.
25.Kleefstra N, Houweling ST, Bakker SJ, et al. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care.
2007 May;30(5):1092-6.
26.Khan, A, Bryden, NA, Polansky, MM, Anderson, RA. Insulin potentiating factor and chromium content of selected foods and spices. Biol Trace Elem.Res 1990;24(3):183-188.
27.Vanadium - help for blood sugar problems? Treatment update. 8-1-1999;11(6):5-7.
28.Sakurai, H. A new concept: the use of vanadium complexes in the treatment of diabetes mellitus. Chem.Rec. 2002;2(4):237-248.
29.Shafrir, E, Spielman, S, Nachliel, I, Khamaisi, M, Bar-On, H, Ziv, E. Treatment of diabetes with vanadium salts: general overview and amelioration of nutritionally induced diabetes in the Psammomys obesus
gerbil. Diabetes Metab Res.Rev. 2001;17(1):55-66.
30.Shao, J, Catalano, PM, Yamashita, H, Ishizuka, T, Friedman, JE. Vanadate enhances but does not normalize glucose transport and insulin receptor phosphorylation in skeletal muscle from obese women with
gestational diabetes mellitus. Am.J.Obstet.Gynecol. 2000;183(5):1263-1270.
31.Shechter, Y. Insulin-mimetic effects of vanadate. Possible implications for future treatment of diabetes. Diabetes 1990;39(1):1-5.
32.Shechter, Y, Shisheva, A. Vanadium salts and the future treatment of diabetes. Endeavour 1993;17(1):27-31.
33.Srivastava, AK. Anti-diabetic and toxic effects of vanadium compounds. Mol.Cell Biochem. 2000;206(1-2):177-182.
34.Thompson, KH, Orvig, C. Vanadium compounds in the treatment of diabetes. Met. Ions. Biol. Syst. 2004;41:221-252.
53
Equine Formulas
Equine Mobility Support
Product Overview
Equine joints inevitably suffer stress during daily
riding, training, and competing. Friction and loadbearing stress on a horse’s joints ultimately affect
comfort and performance, sometimes even before
the signs are apparent.
Supplement Facts
Product Number
E8000
Content
40 ounces (1134 g)
Equine Mobility Support is a scientifically
researched formula that can help:
Serving Size
¼ cup (33 g)
◆◆ Promote
30
healthy joint function, flexibility,
and mobility
◆◆ Supply antioxidants to help protect against
damage from free radicals
◆◆ Support a healthy inflammatory response and
full and firm stride*
Ingredients
Flax meal, glucosamine sulfate (4 g), ginger (root),
chondroitin sulfate (1.5 g), wheat germ oil, honey,
and cinnamon.
Suggested Use
Key Ingredients
Glucosamine sulfate: An important component
of cartilage growth, maintenance, and repair. While
research is ongoing in horses, meta-analysis of
human clinical trials has confirmed the value of
glucosamine in support of bone health.1, 2, 3 In the
horse, glucosamine has been implicated in
regulation of matrix metalloproteinase expression,
an important enzyme working in joint tissues.4, 5
Warnings
For equine use only. Do not administer to cattle or
other ruminants. Keep all supplements out of the
reach of children and other animals. In case of
Precautions
Chondroitin sulfate: An important component
of the extracellular matrix of connective tissue.
Low-molecular-weight chondroitin sulfate is bioavailable in the horse, although to a limited degree.6
While the mechanism of chondroitin sulfate action in joint health remains to be determined, chondroitin
sulfate is an important component of compounds found in various functional components of the joint.
Wheat germ oil: Provides a rich source of vitamin E, which promotes healthy circulation, enhances
athletic performance, and helps reduce muscle cramping. Vitamin E is an important lipophilic
antioxidant implicated in a number of physiological functions. Tocopherols support immune function
and lessen the inflammatory response by scavenging reactive oxygen species.
Flax meal: Contains significant levels of omega-3 fatty acids, specifically alpha-linolenic acid (ALA) and
omega-3 fatty acids, which have been implicated in reducing the inflammatory response. Studies have
shown that omega-3 fatty acids reduced inflammatory thromboxane and decreased endotoxin-induced
TNF production in horses.7, 8
Ginger: Contains a broad spectrum of bioactive compounds. Several ginger compounds have welldocumented effects on the inflammatory response. For example, 6-gingerol and 6-paradol have such
activity, while 8-paradol and 9-shagaol have been shown to inhibit COX-2 activity. This action may
explain ginger’s historic uses.9, 10 This ingredient could be considered a controlled substance by certain entities that govern equine competitions. We advise those who feed any
supplement to competing horses to check with the governing body specific to the event regarding whether the product contains ingredients that could be considered a controlled substance.
54
Horses representing different breeds, ages, and gender were evaluated prior to initiating the study to
define their level of lameness. Animals having a spavin score of greater than 1 in a leg joint were
recruited. Fifteen horses were enrolled in the study and were given ¼ cup (approximately 2 ounces) of
Equine Mobility Support daily for 60 days. Equine participants were re-evaluated at 30-day intervals.
Change in spavin score, or lack thereof, was noted after 30 and 60 days. Serum chemistries and
complete blood-cell counts were performed prior to and during the study to assure no unexpected side
effects developed during the study.
Equine Formulas
Clinical Evaluations
With one exception, all horses showed improvement of aggregate spavin score (total for all limbs) by
30 days. At 60 days, all horses showed continued improvement. In addition, there were no actionable
changes in blood chemistries. Subjective comments from the trainers involved indicated many animals
showed greater range in motion.
Second Trial
Eighteen additional animals were
recruited for assessment. These
animals were more active (dressage,
endurance, jumping, therapy) and
likely to exhibit different stress
symptoms/indicators on their limbs.
Sixteen animals finished the 60-day
trial with a similar protocol. The
results support those found in the
initial trial.
Figure 1: Effect of Equine Mobility Support on lameness (aggregate data)
These studies contained no
control group and represent the
observations and measurements by
the attending veterinarian.
1.Clegg DO, Reda DJ, Harris CL, et. al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006; 354:795-808.
2.McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA. 2000; 283:1469-1475.
3.Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, Hochberg MC, Wells G. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev: CD002946; 2005.
4.Neil KM, Orth MW, Coussens PM, Chan PS, Caron JP. Effects of glucosamine and chondroitin sulfate on mediators of osteoarthritis in cultured equine chondrocytes stimulated by use of recombinant
equine interleukin-1beta. Am J Vet Res. 2005; 66:1861-1869.
5.Chan PS, Caron JP, Orth MW. Effect of glucosamine and chondroitin sulfate on regulation of gene expression of proteolytic enzymes and their inhibitors in interleukin-1-challenged bovine articular cartilage
explants. Am J Vet Res. 2005; 66:1870-1876.
6.Du J, White N, Eddington ND. The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse. Biopharm
Drug Dispos. 2004; 25:109-116.
7.McCann ME, Moore JN, Carrick JB, Barton MH. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in
vitro. Shock. 2000; 14:222-228.
8.Morris DD, Henry MM, Moore JN, Fischer JK. Effect of dietary alpha-linolenic acid on endotoxin-induced production of tumor necrosis factor by peritoneal macrophages in horses. Am J Vet Res. 1991;
52:528-532.
9.Surh Y. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res. 1999; 428:305-327.
10.Tjendraputra E, Tran VH, Liu-Brennan D, Roufogalis BD, Duke CC. Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells. Bioorg Chem. 2001; 29:156-163.
55
Equine Formulas
Equine Performance
Product Overview
Rigorous training and competition can bring on
an inflammatory response, exercise-related
muscle soreness, and oxidative stress. Regardless
of the discipline, quick muscle recovery and
optimal energy levels are essential.
Supplement Facts
Product Number
E8100
Content
30 ounces (850 g)
Equine Performance is specially formulated to
keep equine athletes happy, healthy, and sound by:
Serving Size
¼ cup (30 g)
◆◆ Providing
28
energy substrates (nucleotides,
ribose, amino acids) and supporting energyrelated pathways
◆◆ Offering antioxidant and cognition support
◆◆ Supporting recovery from strenuous activity
or performance
◆◆ Supporting a healthy inflammation response*
Key Ingredients
Glutamate: Central to reactions that generate
energy and support the excretion of excess/
waste compounds from the body. The addition of
this amino acid during exercise supports tissue
levels of glutamate and alanine while also
reducing ammonia during and
following exercise.1
L-glutamine: This amino acid is a universal
energy substrate for hard-working cells
throughout the body, like those of the immune
and gastrointestinal tract.2, 3
Ingredients
glutamic acid, nutritional yeast, rice protein powder,
tart cherry powder, ribonucleic acid, calcium citrate,
magnesium citrate, selenium yeast (550 mcg
selenium), buckwheat (leaf), Brussels sprouts (whole
plant), kale (whole plant), choline bitartrate, inositol,
alfalfa (whole plant) juice powder, sunflower lecithin
powder, grape (seed) extract, carrot (root) powder,
and red wine extract.
Suggested Use
Warnings
Precautions
Nutritional yeast: A rich source of natural
B vitamins, nutritional yeast is included to
support overall cell functions, especially those
related to energy metabolism, as well as
cognitive function.4, 5
56
Equine Formulas
Ribonucleic Acid (RNA): RNA contains nucleotides,
the building blocks of energy molecules like adenosine
triphosphate (ATP), cytidine triphosphate (CTP), and
guanosine triphosphate (GTP). These molecules
support metabolism. The RNA in this product is added
to provide a larger pool of “raw materials” for the base
energy systems that fuel the body. RNA also provides
ribose, an excellent energy source to support
peak performance.6
Selenium: Selenium is part of the protection
mechanisms within cells. As an essential component
of glutathione peroxidase, selenium supports the
metabolism of oxidation products within cells.
Selenium also plays a role in thyroid hormone
metabolism.7, 8, 9
Tart cherry: Historically used for activity-based
inflammatory response, this ingredient’s mechanism
of action is still unknown. Human studies have found
improvements in muscle strength and comfort in
those consuming tart cherry as compared to those
consuming a placebo.10, 11
Equine Feeding Tips
Here are a few tips to make sure horses consume their daily dose of supplement:
◆◆ Start
slowly. Introduce the product in small amounts to let the animal get used to the taste.
a wet feed so the powder mixes in with the rations. This will also prevent the powder from
falling to the bottom of the bucket.
◆◆ Mix with sugar-free applesauce and horse’s feed.
◆◆ Make a mash using commonly found low-starch and pelleted feeds or soaked hay cubes.
◆◆ Mix with applesauce and syringe directly into mouth.
◆◆ Make
1.Mourtzakis M, Graham TE. Glutamate ingestion and its effects at rest and during exercise in humans. Appl Physiol. 2002 Oct;93(4):1251-9.
2.Ehrlich, SD. (2009, June 20) Complementary Medicines. Glutamine. July 29, 2011; http://www.umm.edu/altmed/articles/glutamine-000307.htm.
3.Lacey JM and Wilmore DW. Is glutamine a conditionally essential amino acid? Nutrition Reviews. 2009; 48(8): 297-309.
4.Depeint F, et al. (2006). Mitochondrial function and toxicity: Role of the B vitamin family on mitochondrial energy metabolism. Chemico-Biological Interactions. 163(1-2):94-112.
5.Malouf, R and Grimley EJ. (2003). The effect of vitamin B6 on cognition. Cochrane Database Syst Rev. (4):CD004393.
6.Carver JD. Dietary nucleotides: effects on the immune and gastrointestinal systems. Acta Paediatr Suppl. 1999; 430:83-88.
7.Karren BJ, et al. Effect of selenium supplementation and plane of nutrition on mares and their foals: selenium concentrations and glutathione peroxidase. J anim Sci. 2010; 88(3):991-7.
8.De Moffarts B, et al. Effects of oral antioxidant supplementation on blood antioxidant status in trained thoroughbred horses. Vet J. 2005; 169(1):7-9.
9.Avellini L, et al. Effect of exercise training, selenium and vitamin E on some free radical scavengers in horses (Equus caballus). Comp Biochem Physiol B Biochem Mol Biol. 1999; 123(2):147-54.
10.Ducharme NG et al. Effect of a tart cherry juice blend on exercise-induced muscle damage in horses. Am J Vet Res. 2009; 70(6): 758-63.
11.Connolly DA, et al. Efficacy of a tart cherry juice blend in prevention the symptoms of muscle damage. Br J Sports Med. 2006; 40(8):679-83.
57
References, Glossary, and FAQs
Key Ingredient Cross-Reference
Use this quick reference to find the products that contain specific ingredients as one of their primary
ingredients. Please reference the individual product description to see all of the ingredients in a certain product.
Adrenal
Bovine Bile Salts
Canine Adrenal Support, Canine Musculoskeletal Support, Canine
Renal Support, Canine Thyroid Support, Feline Cardiac Support,
Canine Dermal Support, Canine Enteric Support, Canine Immune
System Support
Adrenal Cytosol™ Extract
Equine GI Support, Equine Performance, Equine
Immune Support
Canine Adrenal Support, Canine Dermal Support, Canine Immune
System Support, Canine Whole Body Support, Feline Cardiac
Support, Feline Immune System Support, Feline Renal Support,
Adrenal PMG™ Extract
Canine Adrenal Support, Canine Dermal Support, Canine Enteric
Support, Canine Immune System Support, Canine Thyroid Support,
Alfalfa Juice
Canine Adrenal Support, Canine Cardiac Support, Canine Dermal
Support, Canine Enteric Support, Canine Hepatic Support, Canine
Musculoskeletal Support, Canine Renal Support, Canine Thyroid
Support, Canine Whole Body Support, Feline Cardiac Support,
Feline Enteric Support, Feline Hepatic Support, Feline Immune
System Support, Feline Renal Support, Feline Whole Body Support
Allantoin
Canine Adrenal Support, Canine Enteric Support, Canine Hepatic
Support, Canine Renal Support, Feline Enteric Support, Feline
Whole Body Support
Antronex® Base
Canine Dermal Support, Canine Hepatic Support, Canine Whole
Body Support, Feline Hepatic Support
Arginex® Base (Extract of Rhizopus oryzae grown on Tillandsia
usneoides and beet root)
Canine Musculoskeletal Support, Canine Renal Support, Feline
Hepatic Support, Feline Renal Support, Feline Whole Body Support
Beet Leaf Juice
Canine Dermal Support, Canine Enteric Support, Canine Hepatic
Support, Canine Musculoskeletal Support, Feline Hepatic Support,
Feline Renal Support, Feline Whole Body Support
Beet Root
Canine Cardiac Support, Canine Dermal Support, Canine Enteric
Support, Canine Hepatic Support, Canine Musculoskeletal Support,
Canine Renal Support, Canine Whole Body Support, Feline Hepatic
Support, Feline Renal Support, Feline Whole Body Support
Black Currant Juice
Canine Adrenal Support, Canine Dermal Support, Canine Immune
System Support, Canine Musculoskeletal Support, Canine
Renal Support
Black Currant Seed Oil
Buckwheat
Canine Adrenal Support, Canine Cardiac Support, Canine Hepatic
Support, Canine Immune System Support, Canine Musculoskeletal
Support, Canine Renal Support, Canine Thyroid Support, Feline
Cardiac Support, Feline Hepatic Support, Feline Immune System
Support, Feline Renal Support, Feline Whole Body Support, Equine
Metabolic Support, Equine GI Support, Equine Performance,
Equine Immune Support
Calcium Glycerophosphate
Canine Enteric Support, Canine Hepatic Support, Canine
Musculoskeletal Support, Canine Thyroid Support
Calcium Lactate
Canine Cardiac Support, Canine Dermal Support, Canine Hepatic
Support, Canine Thyroid Support, Canine Whole Body Support,
VF Antronex®, VF Thymex®
Carrot
Immune System Support, Canine Musculoskeletal Support, Canine
Renal Support, Canine Thyroid Support, Canine Whole Body
Support, Feline Enteric Support
Cayenne
Chamomile
Equine GI Support
Chlorophyll Extract
Support, Canine Enteric Support, Canine Hepatic Support,
Canine Musculoskeletal Support, Canine Renal Support, Feline
Enteric Support
Choline Bitartrate
Canine Cardiac Support, Canine Hepatic Support, Canine Whole
Body Support, Feline Hepatic Support, Feline Whole Body Support
Chondroitin Sulfate
Canine Flex Support, Equine Mobility Support
Chromium
Canine Hepatic Support, Canine Immune System Support, Canine
Musculoskeletal Support, Canine Renal Support
Cinnamon
Bone Meal
Copper Liver Chelate
Canine Dermal Support, Canine Thyroid Support, Canine Whole
Body Support, Feline Cardiac Support, Feline Hepatic Support,
Feline Renal Support, Feline Whole Body Support
Canine Hepatic Support, Canine Whole Body Support, Feline
Hepatic Support, Feline Immune System Support
Crataegus oxyacantha (Hawthorn)
Boswellia serrata (Boswellia)
Canine Cardiac Support, Feline Cardiac Support
Canine Musculoskeletal Support
58
Brussels Sprouts
Equine Metabolic Support, Equine Mobility Support
Duodenum
Kelp
Support, Canine Thyroid Support, Feline Enteric Support, Feline
Hepatic Support, Feline Renal Support
Canine Adrenal Support, Canine Immune System Support, Canine
Support, Feline Cardiac Support, Feline Immune System Support
Eleutherococcus senticosus (Eleuthero)
Renal Support, Canine Whole Body Support, Feline Cardiac
Support, Feline Enteric Support, Feline Hepatic Support, Feline
Immune System Support, Feline Renal Support, Feline Whole
Body Support
Canine Adrenal Support, Canine Immune System Support, Canine
Musculoskeletal Support, Canine Thyroid Support, Feline Immune
System Support
Emblica officinalis (Indian Gooseberry)
Canine Dermal Support, Feline Cardiac Support, Feline Hepatic
Flax Meal
Equine Mobility Support
Ginger
Glucosamine Sulfate
Glutamate
Equine Performance
Green Tea
Heart PMG™ Extract
Canine Cardiac Support, Canine Hepatic Support, Canine
Musculoskeletal Support, Canine Thyroid Support, Canine Whole
Body Support, Feline Cardiac Support, Feline Renal Support, Feline
Whole Body Support
Hypothalamus Cytosol™ Extract
Canine Whole Body Support, Feline Immune System Support
Hypothalamus PMG™ Extract
Inositol
Canine Cardiac Support, Canine Dermal Support, Canine Hepatic
Support, Canine Whole Body Support, Feline Hepatic Support,
Inulin
Equine GI Support
Iron Liver Chelate
Canine Whole Body Support, Feline Hepatic Support, Feline
Jejunum
Support, Feline Enteric Support, Feline Immune System Support,
Kale
Equine GI Support, Equine Performance, Equine Immune Support
Kidney
Brussels Sprouts
Kidney Bean Extract
Canine Renal Support, Canine Whole Body Support, Feline Renal
Support, Feline Whole Body Support
Kidney PMG™ Extract
Canine Renal Support, Canine Whole Body Support, Feline Hepatic
Support, Feline Renal Support, Feline Whole Body Support
L-carnitine
Canine Cardiac Support, Canine Whole Body Support, Feline
Cardiac Support, Feline Whole Body Support
L-glutamine
Support, Feline Enteric Support, Feline Hepatic Support, Feline
Immune System Support, Feline Whole Body Support, Equine GI
Support, Equine Immune, Equine Performance
Licorice Root
Liver
Support, Canine Enteric Support, Canine Flex Support, Canine
Hepatic Support, Canine Immune System Support, Canine
Support, Canine Whole Body Support, Feline Cardiac Support,
Feline Enteric Support, Feline Hepatic Support, Feline Immune
System Support, Feline Renal Support, Feline Whole Body Support
Liver PMG™ Extract
Support, Canine Whole Body Support, Feline Hepatic Support,
Manganese Glycerophosphate
Canine Adrenal Support, Canine Renal Support, Canine Whole
Body Support
Mushroom
Support, Equine Immune Support
59
Nutritional Yeast
Sunflower Lecithin
Immune System Support, Canine Renal Support, Canine Whole
Body Support, Feline Cardiac Support, Feline Enteric Support,
Feline Hepatic Support, Feline Whole Body Support
Canine Adrenal Support, Canine Musculoskeletal Support, Canine
Thyroid Support, Canine Whole Body Support
Orchic Cytosol™ Extract
Canine Immune System Support, Canine Whole Body Support,
Canine Musculoskeletal Support, Canine Renal Support, Canine
Whole Body Support, Feline Cardiac Support, Feline Immune
System Support, Feline Whole Body Support
Orchic Extract
Thyroid Support
Pancreas Cytosol™ Extract
Canine Cardiac Support, Canine Enteric Support, Canine Immune
System Support
Pea Vine Juice
Canine Adrenal Support, Canine Cardiac Support, Canine Enteric
Support, Canine Renal Support, Canine Thyroid Support, Canine
Whole Body Support, Feline Cardiac Support, Feline Hepatic
Perna canaliculus (Green-lipped mussel)
Equine Performance
Thymus Cytosol™ Extract
Thymus PMG™ Extract
Canine Immune System Support, Canine Whole Body Support
Thyroid PMG™ Extract
Canine Adrenal Support, Canine Hepatic Support, Canine
Support, Canine Whole Body Support, Feline Immune
System Support
Tillandsia usneoides (Spanish Moss)
Canine Cardiac Support, Canine Enteric Support, Canine Hepatic
Support, Canine Thyroid Support, Canine Whole Body Support,
Feline Cardiac Support, Feline Renal Support
Trachea
Canine Musculoskeletal Support, Canine Whole Body Support,
Turmeric
Canine Dermal Support, Canine Hepatic Support, Canine
Musculoskeletal Support, Canine Thyroid Support, Feline Enteric
Support, Feline Hepatic Support, Feline Renal Support, Feline
Whole Body Support
Canine Flex Support, Equine Immune Support
Pituitary PMG™ Extract
Support, Canine Hepatic Support, Canine Immune System
Support, Canine Musculoskeletal Support, Canine Renal Support,
Canine Whole Body Support, Feline Enteric Support, Feline
Renal Support
Support, Canine Renal Support, Canine Whole Body Support,
Ribonucleic Acid
Canine Cardiac Support, Canine Hepatic Support, Canine Immune
System Support, Canine Musculoskeletal Support, Canine Renal
Support, Canine Thyroid Support, Feline Cardiac Support, Feline
Immune System Support, Feline Renal Support
Rice Bran
Support, Canine Renal Support, Canine Thyroid Support, Canine
Whole Body Support, Feline Cardiac Support, Feline Enteric
Whole Body Support
Selenium
Equine Performance
Silybum marianum (Milk Thistle)
Canine Dermal Support, Canine Hepatic Support, Canine Whole
Body Support, Feline Hepatic Support
Spleen
Canine Cardiac Support, Canine Dermal Support, Canine Enteric
Support, Canine Renal Support, Canine Whole Body Support,
Feline Cardiac Support, Feline Enteric Support, Feline Hepatic
Stomach
Support, Canine Whole Body Support, Feline Enteric Support,
60
Tart Cherry
Vanadium
Veal Bone PMG™ Extract
Wheat Germ
Thyroid Support, Canine Whole Body Support, Feline Enteric
Whole Body Support, VF Bio-Dent®
Wheat Germ Oil
Support, Canine Hepatic Support, Canine Musculoskeletal Support,
Canine Renal Support, Canine Thyroid Support, Feline Cardiac
Support, Feline Enteric Support, Feline Hepatic Support
Zinc Liver Chelate
Canine Hepatic Support, Canine Immune System Support, Canine
Whole Body Support, Feline Hepatic Support, Feline Immune
System Support, Feline Whole Body Support
Beet leaves
Glossary
Grown on Standard Process
certified organic farm
Acid maltase—An enzyme that breaks down carbohydrates.
Breaks off individual glucose molecules from the maltose
units. In combination with amylase and glucoamylase,
these enzymes complete the breakdown of starch and
other carbohydrates.
Alfalfa (Medicago sativa)—A perennial flowering legume.
Alginic acid—An organic acid from various algae species.
Antioxidants—Substances found in food, especially fruits
and vegetables.
Arabic gum—A natural gum from the acacia tree, arabic gum
is used to make tablets—a collodial stabilizer.
Barley—Barley grass used in our formulas consists of the
green leaves of the barley plant as opposed to the grain.
Beet root—The underground portion of a beet plant.
Beet leaves—The above-ground portion of a beet plant; also
known as Swiss chard.
Bentonite (montmorillonite)—A natural colloidal, adsorbing
clay that can bind substances present in the lumen of the
digestive tract, allowing these substances to be eliminated
with the fecal material.
Beta carotene—The yellow pigment found in many yellow and
orange fruits, such as carrots.
Betaine—A sweet, crystalline, quaternary ammonium salt
found in beet juice. Can be used as a lipotropic factor or a
gastric acidifier.
Biotin—A member of the B-vitamin family that helps support
energy and amino acid metabolism. Nutritional yeast,
liver, kidney, whole grains, nuts, and eggs are good sources
of biotin.
Black currant seed oil—the oil of a black currant plant
contains gamma-linolenic acid.
Boswellia serrata (Boswellia)—a moderate to large sized
branching tree of the family Burseraceae, traditionally used
to support healthy inflammatory response.
Bovine—Cow.
Bovine bile salts—A purified source of bovine bile salts in a
powdered form.
Bromelain—Protein-digesting and milk-clotting enzyme
generally found in pineapple fruit juice and stem tissue.
Brussels sprouts—A Brasscia related to broccoli and cabbage.
Buckwheat—A member of the Polygonaceae family, buckwheat
is related to sorrel, knotweed, and rhubarb.
Calcium glycerophosphate—A white crystalline powder that
is soluble in cold water.
Calcium lactate—A source of calcium. (Not derived from a
dairy product or source.)
Calcium stearate—A plant-based stearic acid used for
lubrication in the manufacture of products.
Carbamide powder—A food-grade urea.
Carthamus tinctorius (safflower)—a plant appearing to have a
supportive effect on the cardiovascular system.
Chlorophyll extract—A fat-soluble extract from plant
material. It acts to support tissue health, maintenance,
and regeneration. Chlorophyll is regarded as a natural
gastrointestinal (GI) tract deodorant and cleanser.
Choline bitartrate—A vitamin of the B complex essential to
liver function.
Chromium yeast—An excellent source of chromium.
Copper chelate—Provides an excellent source of copper.
Copper is an essential trace mineral that is important for a
wide range of biochemical processes.
Crataegus oxyacantha (hawthorn)—a well-known heart and
vascular tonic.
61
Glossary
Grown on Standard Process
certified organic farm
Cytosol™ extract—Cytosol™ is the trademark owned and used
by Standard Process Inc. as a brand name for extracts
derived from the cytoplasm of the cell. They contain the
“materials” such as enzymes, hormone precursors, and
synergistic cofactors produced by the cell. These materials
serve as the building blocks for cellular metabolic end
products that are utilized by the cell itself or transported
outside the cell.
Defatted wheat germ—Wheat germ is noted for its dense
nutritional content of the vitamin B complex and many
important trace minerals essential for the full physiological
activity of the associated vitamin complexes.
Dicalcium phosphate—A calcium compound used in calcium
therapy.
Eleutherococcus senticosus (eleuthero)—several species of this
plant grow around the world, and though some are preferred
for specific benefits, all are considered to have similar
properties as an effective general rejuvenator
Emblica officinalis (Indian gooseberry)—an herb that has
traditionally been used for the purposes of enhancing
general vitality and cognition as well as promoting longevity
Flax meal—contains significant levels of omega-3 fatty acids,
specifically alpha-linoleic acid (ALA)
Ginger—a thickened pungent aromatic rhizome that contains a
broad spectrum of bioactive compounds.
Ginkgo biloba—Made from leaves and seeds of the ginkgo
tree, Ginkgo biloba has a long history of use in traditional
Chinese medicine.
Lutein—A type of phytochemical with antioxidant activity
known as carotenoid (or natural pigment). Lutein is found in
dark green leafy vegetables, such as kale.
Magnesium lactate—Source of magnesium
Manganese glycerophosphate—A source of manganese,
an essential trace mineral important for skeletal and
cartilage formation.
Manganese lactate—A manganese salt derived from lactic
acid that is a source of manganese. Manganese acts as a
cofactor and catalyst in many enzymatic processes.
Micronutrients—Essential nutritional elements required in very
small or trace amounts for the body to function properly.
Examples include iron, copper, manganese, and zinc.
Milk thistle (Silybum marianum)—An annual or biannual plant
of the Asteraceae family, its scientific name is Silybum
marianum.
Mixed tocopherols—The antioxidant component of the
vitamin E complex.
Mushroom—available in many varieties and has a long history
of use in traditional Chinese medicine.
Nutritional yeast—Inactive yeast with high protein and
B-vitamin content.
Oats—A hardy cereal grain, common oats are known
scientifically as Avena sativa.
Glucosamine sulfate—a naturally occurring chemical
harvested from the shells of shellfish.
Ovine—Sheep.
Inositol—A component of the B-vitamin complex. Inositol acts
as an important catalyst in energy reactions that involve the
metabolizing of some fats and carbohydrates.
Pea vine juice—The extracted juice from the pea vine.
Inulin—A complex carbohydrate and soluble fiber. It is beneficial
to the gut microflora and supports calcium and magnesium
absorption. Inulin is found naturally in many common plants,
especially chicory.
Iron chelate—Provides an excellent source of iron. Iron is
an important nutrient essential for a wide range of vital
biological processes, including the synthesis of hemoglobin,
and is also involved in the entire process of respiration,
including oxygen and electron transport.
Kale—A green leafy cruciferous plant that belongs to the
Brassica family, a group of vegetables including cabbage,
collards, and Brussels sprouts.
Kelp—Brown seaweed of the genius Laminaira that is a good
source of trace minerals.
Kidney bean (Phaseolus vulgaris)—An annual legume.
L-carnitine—Carnitine is required for transporting longchain fatty acids into the cells, which is essential for the
conversion of fatty acids into energy for the cells, especially
in heart muscle. (See the Primary Ingredient Cross Reference
for products listed under Heart PMG™ Extract, Bovine; Liver
PMG™ Extract, Bovine; and Liver Powder, Bovine.)
62
L-glutamine—An amino acid used to make other amino acids,
glucose, and glutathione. Used for energy by immune and
intestinal cells.
Pea vine—An annual leguminous vine.
Phytonutrient—Biologically active nutrients found in plants
that give them their color and taste. Also referred to as
phytochemicals, they are known to have health-promoting
properties.
Porcine—Pork.
Protomorphogen™ extract—In the 1940s, Dr. Royal Lee
pioneered a unique method of deriving extracts that contain
what he called cell determinants from specific organs
and glands for clinical use. He believed that these cell
determinants functioned in cell regulation, maintenance, and
interaction with tissue antibodies. It is clear both from the
description of the extraction process and clinical use that
these extracts differ from what is commonly referred to as
“glandulars.” Furthermore, because these extracts have a
distinct clinical application and effect, they should not be
confused with glandulars, nor should they be referred to
simply as “protomorphogens.” Rather, Protomorphogen™ is
the trademark owned and used by Standard Process Inc. as
a brand name assigned to these uniquely derived extracts.
PMG™ is another trademark owned and used by Standard
Process Inc. as another brand name for these extracts.
Rhizopus oryzae—A mold grown on Tillandsia usneoides and
beet root as a source of enzymes.
Botanical Name . . . . . . . . . . . . Common Name
Common Name . . . . . . . . . . .
Botanical Name
Arctium lappa . . . . . . . . . . . . . . . . . . . . . . .burdock
Boswellia . . . . . . . . . . . . . . . . . . . . Boswellia serrata
Berberis aquifolium . . . . . . . . . . . . . . . . . Oregon grape
Burdock . . . . . . . . . . . . . . . . . . . . . . Arctium lappa
Boswellia serrata . . . . . . . . . . . . . . . . . . . . boswellia
Cayenne pepper . . . . . . . . . . . . . . . . . Capsicum annuum
Capsicum annuum . . . . . . . . . . . . . . . . . cayenne pepper
Dandelion . . . . . . . . . . . . . . . . . . Taraxacum officinale
Centella asiatica . . . . . . . . . . . . . . . . . . . . gotu kola
Echinacea . . . . . . . . . . . . . . . . . Echinacea angustifolia
Coriolus versicolor . . . . . . . . . . . . . . turkey tail mushroom
Echinacea . . . . . . . . . . . . . . . . . . . Echinacea purpurea
Cynara scolymus . . . . . . . . . . . . . . . . . . globe artichoke
Filamentous fungi . . . . . . . . . . . . . . . . . Rhizopus oryzae
Echinacea angustifolia . . . . . . . . . . . . . . . . .echinacea
Ginkgo . . . . . . . . . . . . . . . . . . . . . . . Ginkgo biloba
Echinacea purpurea . . . . . . . . . . . . . . . . . . .echinacea
Globe artichoke . . . . . . . . . . . . . . . . . .Cynara scolymus
Ginkgo biloba . . . . . . . . . . . . . . . . . . . . . . . . ginkgo
Gotu kola . . . . . . . . . . . . . . . . . . . . . Centella asiatica
Grifola frondosa . . . . . . . . . . . . . . . . maitake mushroom
Juniper berry . . . . . . . . . . . . . . . . . Juniperus communis
Juniperus communis . . . . . . . . . . . . . . . . . juniper berry
Maitake mushroom . . . . . . . . . . . . . . . . Grifola frondosa
Pygeum africanum . . . . . . . . . . . . . . . . . . . . pygeum
Milk thistle . . . . . . . . . . . . . . . . . . . Silybum marianum
Rhizopus oryzae . . . . . . . . . . . . . . . . . filamentous fungi
Nettle . . . . . . . . . . . . . . . . . . . . . . . . . Urtica dioica
Serenoa repens . . . . . . . . . . . . . . . . . . . saw palmetto
Oregon grape . . . . . . . . . . . . . . . . . Berberis aquifolium
Silybum marianum . . . . . . . . . . . . . . . . . . milk thistle
Pygeum . . . . . . . . . . . . . . . . . . . . .Pygeum africanum
Taraxacum officinale . . . . . . . . . . . . . . . . . . dandelion
Red clover . . . . . . . . . . . . . . . . . . . Trifolium pratense
Tillandsia usneoides . . . . . . . . . . . . . . . . . Spanish moss
Saw palmetto . . . . . . . . . . . . . . . . . . . Serenoa repens
Trifolium pratense . . . . . . . . . . . . . . . . . . . . red clover
Spanish moss . . . . . . . . . . . . . . . . . Tillandsia usneoides
Urtica dioica . . . . . . . . . . . . . . . . . . . . . . . . . nettle
Turkey tail mushroom . . . . . . . . . . . . . . Coriolus versicolor
Ribonucleic acid—Nucleic acid occurring in cell cytoplasm
and the nucleolus, first isolated in plants but later found in
animal cells.
Selenium yeast—A rich source of selenium. Selenium is
an essential trace element that has antioxidant activity
mediated through its role in the formation and function of
selenium-dependent glutathione peroxidases. Also believed
to help maintain a healthy heart and joints.
Silybum marianum (milk thistle)—This species is an annual or
biennial plant of the Asteraceae family.
Soybean lecithin—A rich source of lecithin, a precursor to
choline. A substance that is crucial for proper central
nervous system, liver, cardiovascular, and immune system
health. A rich source of phospholipids.
Spanish black radish—An excellent source of sulfur, which
protects against free radicals and is also beneficial in the
healthy functioning of the GI tract.
Sunflower lecithin—A type of phospholipid found in
sunflower seeds.
Taraxacum officinale (dandelion)—a flowering herbaceous
perennial plant of the family Asteraceae.
Tart cherry—a fleshy stone fruit known for its
antioxidant properties.
Thiamine (vitamin B1)—a water soluble vitamin that works with
the other B vitamins to change protein, carbohydrate, and
fat to energy.
Botanical and Common Name Reference
Tillandsia usneoides (Spanish moss)—A plant belonging to the
pineapple family, grown in the southeastern coastal plain of
the United States. It is a nonparasitic plant that is supported
by another plant and has aerial roots exposed to the
humid atmosphere.
Turmeric—An Indian perennial herb of the ginger family.
Vanadium—A grayish metallic element found combined
in minerals.
Wheat germ oil—One of the richest sources of the complete
vitamin E complex. Vitamin E is beneficial in multiple
metabolic processes.
Whey protein—Whey (milk) protein is the protein and amino
acid components extracted from whey. Whey is the clear
liquid left after the protein of milk has been clotted and
most of the fat removed, e.g., after cheese production.
Whole desiccates—The whole, dried glandular tissue.
It contains proteins of the entire organ or gland in a
concentrated form.
Withania somnifera (ashwaganda, Indian ginseng)—part of the
Solanaceae family, this plant’s tuberous roots are used for
therapeutic uses.
Yakriton—A liver fat extract.
Zinc chelate—Contains zinc that is bound to bovine liver to
maintain healthy zinc levels.
63
The 420-acre Standard Process certified organic farm is just down the road from corporate headquarters.
FAQs
The most commonly asked questions about Standard Process and our products:
Q What ingredients are organically grown
on the Standard Process Farm?
(See Page 12 for more information.)
A The crops we grow organically are: alfalfa, barley
grass, beets, Brussels sprouts, buckwheat, kale,
kidney beans, oats, pea vine, Spanish black
radish, and sweet potatoes.
Q What is Standard Process’ seed source?
Are the seeds genetically modified?
A All of the seeds we use on our farm are untreated
and are not genetically modified. We use certified
organic seeds when available.
Q Why would a product look different from
bottle to bottle?
A Because of the variability in sources of natural
and organic ingredients, color, texture, and odor
may vary from batch to batch. However, the
basic formula remains constant, and quality is
ensured by repeated testing.
Q Why are honey, arabic gum, cellulose, and
calcium stearate added to products?
A Honey and arabic gum are used as binders in our
tablet manufacturing process. Cellulose is used
to give body to the powders. Calcium stearate,
derived from vegetable sources, is used as a
lubricant to help products release from the tablet
machines. No artificial flavoring is ever used.
64
Q Is your calcium stearate derived
from hydrogenated oils? Is it safe
for consumption?
A The calcium stearate we use is derived from
palm oil, which is a saturated fat, like cocoa
butter, dairy fats, etc. Calcium stearate is
approved by the FDA to be used as a lubricant
and is approved for use in food products.
Q Why is sucrose listed on your labels?
A The sucrose found in our products comes from
natural sources such as beets and sugar cane.
Sucrose, along with starch and arabic gum, is
used to coat vitamin A and vitamin D
(cholecalciferol), making them into a powdered
form that helps prevent oxidation of these
vitamins. The amount of sucrose in the actual
product is very minimal.
Q Why is it better to take supplements
throughout the day instead of all at once?
A The body processes most compounds based on
concentration; so the more there is, the faster
your body works to process it. The key is getting
the right concentration at the right time. Taking
smaller amounts throughout the day allows the
body to maintain a lower but more consistent
amount for a longer period of time. It is more
efficient for the body and more effective in
sustaining the molecular mechanisms supported
by the compounds in our supplements.
A The “Best Used By” information, located on all
product boxes and on the shoulder of all product
bottles, represents the date by which the product
is best used by and the product code. The “Best
Used By” date should not be viewed as an
expiration date but as a guideline for when
products are considered 100 percent potent.
Products tend to lose potency over time but may
still be considered effective after this date.
Standard Process only guarantees product
potency
Used
By”
W
HOLE F OODup until the “Best
Standard
Process
Inc.date.
S UPPLEMENTS S INCE 1929
P.O. Box 904 | Palmyra, WI 53156
Products are continuously tested to determine
their shelf life. This testing has shown that
certain products tend to have shorter shelf lives,
which is reflected in the “Best Used By” date.
How to Read the ‘Best Used By’ Information
In this example, the product is best used by
September 2016. Product code numbers are used
to determine when products are produced. In the
example, the product code is L082814001.
L = lot number
08 = month produced (August)
28 = day produced (August 28)
14 = year produced (2014)
001 = randomized three-digit portion used for
internal tracking
For example:
Best Used By
09-16
L082814001
Date
Lot Code
Q What does the ‘Best Used By’ date mean?
Q How do you read your product labels?
A Below is an example of the different parts of our label and what they refer to.
W HOLE F OOD S UPPLEMENTS S INCE 1929
Product name
Standard Process Inc. | P.O. Box 904 | Palmyra, WI 53156
Product number
Serving size
Serving Size: ½ level teaspoon
Canine Whole
Body Support
A2050
Dietary
Supplement
Servings per Container: 70
Ingredients: Defatted wheat germ, bovine liver, pea vine juice, nutritional yeast, carrot, rice
bran, bovine and ovine spleen, alfalfa juice, Silybum marianum, beet root, porcine stomach,
oat flour, bovine heart PMG™ extract, Tillandsia usneoides, L-carnitine, Brussels sprouts, bovine
orchic Cytosol™extract, kidney bean extract, kelp, bovine liver PMG™ extract, bone meal, bovine
trachea, bovine kidney PMG™extract, mushroom, bovine kidney, inositol, choline bitartrate,
thiamine hydrochloride, bovine adrenal Cytosol™extract, celery, bentonite, veal bone PMG™
extract, bovine liver fat extract, calcium lactate, manganese glycerophosphate, carbamide,
bovine adrenal PMG™ extract, bovine hypothalamus Cytosol™ extract, bovine thymus PMG™
extract, bovine pituitary PMG™ extract, zinc rice chelate, copper rice chelate, iron rice chelate,
sunflower lecithin, bovine hypothalamus PMG™ extract, bovine thymus Cytosol™extract, bovine
thyroid PMG™ extract, para-aminobenzoate, porcine brain, and ascorbic acid.
Minerals:
Calcium
5 mg / ½ tsp.
Sodium
14 mg / ½ tsp.
Iron
500 mcg / ½ tsp.
Copper
200 mcg / ½ tsp.
Manganese 600 mcg / ½ tsp.
Zinc
300 mcg / ½ tsp.
Dose Schedule:
Based on body weight, the
canine patient should receive
the canine formula powder
according to the following
recommendations or as
otherwise directed.
1-10 lbs. 1/ 8 tsp. 1x / day
11-20 lbs. 1/ 8 tsp. 2x / day
21-40 lbs. ¼ tsp. 2x / day
41-60 lbs. ½ tsp. 2x / day
61-80 lbs. ¾ tsp. 2x / day
> 80 lbs. 1 tsp. 2x / day
100 Grams
WHOLE FOOD SUPPLEMENTS SINCE 1929
Product size
Ingredients—ingredients that
contribute to the label claims; listed
from “most to least” based on formula
Dose Schedule—recommended
product dosage based on body weight
Made in
the USA
This product is sold by weight
not volume; some settling may occur.
Servings per container
07
Nutrient claims for the product—
order mandated by the FDA
Standard Process Inc.
P.O. Box 904 | Palmyra, WI 53156
Universal Product Code (UPC)—
current UPCs are listed on our website
65
In between product runs, the equipment used in our manufacturing process and the surrounding production suite is cleaned
and sanitized.
FAQs
The most commonly asked questions about Standard Process and our products:
Q How is the manufacturing equipment
cleaned between different product runs?
Q What do I need to consider when
recommending a combination of products?
A Between each separate product run, any
equipment that comes in contact with
ingredients or finished product is disassembled
and washed.
DD Swab samples are taken from several areas of
each piece of equipment.
A Standard Process products are thought to work
synergistically and support multiple aspects of
health. In some cases, combined products can
result in very high levels of certain vitamins or
minerals. Where warranted, guidance is provided
for individual products on the label and in this
catalog via warnings and cautions.
These samples are exposed to a luminometer,
which fluoresces in proportion to the amount of
adenosine triphosphate (ATP) in the sample. ATP
is found in and around all biological matter and
would indicate a possible bacterial presence.
DD
DD
If the luminometer measures ATP results
beyond an acceptable level, the cleaning
process is repeated and additional ATP tests
are conducted.
After the cleaned equipment passes the ATP
testing protocol, the equipment is sanitized.
Only then is the equipment reassembled for use
with a new batch of product.
If a clean piece of equipment is unused for more
than 24 hours, it is resanitized prior to use.
DD
DD
66
Sanitizers are rotated monthly to avoid
bacterial resistence.
In addition to the equipment itself, the
surrounding production suite, including the
floors, walls, and vent covers, is cleaned.
A Visit standardprocess.com or speak to Customer Service for details.
Practitioner Tools
DD
DD
Flyers—details products for various health conditions
Webinars—make it convenient to learn from the experts about recent research and
product information
Client Education Tools
DD
Brochures—helps clients understand the benefits of Standard Process products and
nutrition, clarify the whole food difference, and define our commitment to quality
Q What support materials are available from Standard Process?
L4664 Whole Food Supplements for Pets Brochure
L4593 Equine Brochure
L4589 Canine and Feline Formulas Overview Handout
67
Contact Us
Veterinary Support
Complimentary nutrition consultations for veterinary professionals are available by phone or email.
Phone: 888-982-8130 | Email: [email protected]
Learn more about our technical support team at standardprocess.com.
68
1200 W. Royal Lee Drive | Palmyra, WI 53156
standardprocess.com | [email protected]
C
Customer Service p 800-558-8740
Corporate Office p 800-848-5061
Contact Us
Standard Process Inc.
Sales Department p 800-848-5061, ext. 6492
[email protected]
C
B
E
D
A
C
If you have clinical questions or need guidance using whole food supplements,
please contact your local Standard Process representative or distributor.
Sales Representatives
A
Sales representative contact information can be found on our website at
standardprocess.com.
Distributors
B
C
D
E
Standard Process
West, Inc.
Standard Process
NW, Inc.
Standard Process of
Northern California, Inc.
Standard Process of
Pennsylvania, Inc.
Colorado, Montana, Nebraska,
Alaska, Hawaii, Idaho,
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Pennsylvania
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Oregon, Washington
Utah, Wyoming
Phone
Phone
Phone
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69
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1200 W. Royal Lee Drive | Palmyra, WI 53156
800-848-5061 | Customer Service 800-558-8740 | standardprocess.com
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©2015 Standard Process Inc. (This is a subsequent edition of the work published in 2011.) All rights reserved.
No part of this publication may be reprinted or reproduced in any form without prior written permission from the publisher. L4510 12/15

Veterinary Formulas Product Guide

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