Specially formulated for those with complex GI issues.

Specially formulated for those with complex GI issues.
Vital-Zymes™ Complete is a high-potency, multi-enzyme supplement
formulated for individuals with compromised gastrointestinal function
who require maximum digestive support. Containing an unusually
complete range of plant- and microbial-based enzymes, Vital-Zymes™
Complete helps maintain normal enzyme levels that support the body’s
digestive capabilities and assist intestinal repair mechanisms.
Vital-Zymes™ Complete
Multi-Enzyme Supplement
for Intensive Digestive Support
More comprehensive than standard enzyme blends.
While basic enzyme supplements typically supply protease, amylase, and lipase for digestion of protein,
starch, and fat respectively, these products often lack more specific enzymes needed for optimal digestion
of peptides, disaccharides, fiber, and other food components. In contrast, Vital-Zymes™ Complete contains
a unique blend of 20 enzymes that work in tandem to reduce large, complex molecules into their smallest
units to facilitate healthy digestion and efficient absorption.
Two capsules of Vital-Zymes™ Complete
deliver a broad complement of crucial
enzymes that lend maximum support for
digestion of a full range of foods as found
in a typical meal.
Also available: Vital-Zymes™ Chewable,
a convenient choice for those who may
prefer a chewable tablet.
Vital-Zymes™ Complete
Vital-Zymes™ Chewable
Supplement Facts
Supplement Facts
Serving Size 2 Capsules
Serving Size 2 Chewable Tablets
Amount Per 2 Capsules
Amount Per 2 Chewable Tablets
Comprehensive Enzyme Blend
800 mg*
With the following minimum enzyme activity:
Carbohydrate Specific Enzymes
Amylase
1,830 BAU**
Alpha-Amylase
100 DU**
Glucoamylase (with isomaltase side chain activity)
30 AGU**
Sugar Specific Enzymes
1,500 ALU**
Sucrase (invertase)
400 SU**
Maltase
200 DP**
Pullulanase (debranching enzyme
with isomaltase side chain activity)
25 U**
Vegetable/Plant Fiber Specific Enzymes
Cellulase
500 CU**
Hemicellulase/Pectinase/Phytase Complex
200 HSU**
Phytase
10 PU**
Beta-Glucanase
20 BGI**
Alpha-Galactosidase
40 GaIU**
Galactomannase
200 HCU**
Protein and Peptide Specific Enzymes
Acid Protease
Alkaline Protease
Protease/Peptidase Complex
with endopeptidase, exopeptidase,
and DPP-IV activity
50 SAPU**
50 PC**
40,000 HUT**
Fat Specific Enzyme
Lipase
1,500 FIPU**
Other Enzymes
Lysozyme****
Serratia peptidase (enteric-coated)***
320 mg*
With the following minimum enzyme activity:
Carbohydrate Specific Enzymes
Lactase
Comprehensive Enzyme Blend
100,000 SHU**
2,500 SPU**
*Daily Value not established.
Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water),
vegetable oil powder, and cellulose.
**Units are those used in edition five (V) of the Food Chemicals Codex (FCC)
***Peptizyme SP®, a registered trademark of Specialty Enzymes
****NOTE: Lysozyme is purified from egg white. Individuals with known egg
white allergy should consult their physician prior to use.
K-VZM 120 vegetarian capsules
Amylase
732 BAU**
Alpha-Amylase
40 DU**
Glucoamylase
(with isomaltase side chain activity)
12 AGU**
Sugar Specific Enzymes
Lactase
600 ALU**
Sucrase (invertase)
54 INVU**
Maltase
80 DP**
Pullulanase (debranching enzyme
with isomaltase side chain activity)
10 PUN**
Vegetable/Plant Fiber Specific Enzymes
Cellulase
200 CU**
Hemicellulase/Pectinase/Phytase Complex
80 HSU**
Phytase
4 FTU**
Beta-Glucanase
8 BGU**
Alpha-Galactosidase
16 GaIU**
Galactomannase
80 HCU**
Protein and Peptide Specific Enzymes
Acid Protease
20 SAP**
Alkaline Protease
20 PC**
Protease/Peptidase Complex
with endopeptidase, exopeptidase,
and DPP-IV activity
16,000 HUT**
Fat Specific Enzyme
Lipase
6,000 LU**
Other Enzymes
Serratia peptidase (enteric-coated)***
1,000 SPU**
*Daily Value not established.
Other ingredients: Xylitol, mannitol, stearic acid, silicon dioxide, and natural
cherry flavor.
**Units are those used in edition five (V) of the Food Chemicals Codex (FCC)
***Peptizyme SP®, a registered trademark of Specialty Enzymes
NOTE: Vital-Zymes™ Chewable does not contain lysozyme.
K-VCH 180 chewable tablets
Formulated for Maximum Benefit and Tolerance
Promotes optimal GI function
and digestive comfort.
Enzymes in Vital-Zymes™ Complete can improve intestinal
function, providing temporary relief from flatulence, heartburn,
and other digestive complaints. By facilitating more complete
breakdown of macronutrients, this comprehensive group of
enzymes supports improved nutritional status and reduces
the potential adverse effects of food components such as
incompletely digested casein, gluten, and lactose. Vital-Zymes™
Complete may be helpful for individuals with maldigestion,
malabsorption, dysbiosis, and intestinal inflammation.
Supplies DPP-IV activity specific for
breakdown of casein, gluten, and
other exorphin peptides.
Protein molecules require multiple enzymes for complete digestion.
Proteases degrade proteins into peptides of 10 to 20 amino acids in
length. Peptidases then complete the process by splitting peptides
into single free-form amino acids that are used by the body.
Incompletely digested peptides from casein (casomorphins), gluten
(gluteomorphins), soy, or yeast may adversely affect central nervous
system function in some individuals. Vital-Zymes™ Complete
provides ample amounts of peptidase enzymes that express
dipeptidyl peptidase IV (DPP-IV) activity that is especially effective in
breaking down exorphin (opiate-acting) peptides before they can be
absorbed. While enzymes with DPP-IV activity are normally found in
the cells lining the intestinal tract, it is thought that many individuals
on the autism spectrum may have a deficiency or defect in
DPP-IV activity.
Figure 1. Peptide cleaving by DPP-IV
Supports against carbohydrate
intolerance and dysbiosis.
Vital-Zymes™ Complete contains a wide spectrum of
disaccharidase enzymes to assist optimal cleaving of sugars
including lactose (milk sugar), maltose (from cereal grains),
sucrose (table sugar), and amylopectin (starch) molecules into
their absorbable monosaccharide forms. Insufficient
disaccharidase production by the small intestine can cause
carbohydrate malabsorption and physical discomfort. Lactose
intolerance is the most common form of carbohydrate
intolerance. Incompletely digested sugars or starch can be
fermented by pathogenic organisms and may contribute to yeast
overgrowth (candidiasis) and dysbiosis. Reduced disaccharidase
levels are observed in many children and adults with chronic
diarrhea. Children with dyspepsia typically exhibit low activity
of duodenal maltase, glucoamylase, and/or disaccharidases.
Helps protect GI tissue from
inflammation.
Inflammation of gastrointestinal tissues results from various
causes such as undigested or partially digested food, ingested
or endogenous toxins, intestinal pathogens, and exposure to
allergenic substances. In addition to facilitating more complete
digestion of potentially irritating food components, Vital-Zymes™
Complete supplies Serratia peptidase, a unique endopeptidase
enzyme that helps protect sensitive gastrointestinal tissue from
irritation and subsequent inflammation that can adversely affect
tissue health and intestinal comfort.
Helps support microbial balance.
Vital-Zymes™ Complete also contains lysozyme, an antibacterial
enzyme found in tears, human breast milk, saliva, and nasogastric
and bronchial secretions. Lysozyme promotes protective barrier
function in these tissues against infectious pathogens by
degrading polysaccharides found in the cell walls of many
bacteria, yeast, and other pathogens. In the gastrointestinal
tract, lysozyme’s action helps support a balanced microbial
population and complements the benefits of the other enzymes
in supporting intestinal health.
NOTE: Lysozyme is a highly purified, pharmaceutical grade material derived from hen
egg white. While typically well-tolerated, those with classic IgE mediated egg white
allergy should consult with a physician before use. Vital-Zymes™ Chewable does not
contain lysozyme for those who may wish to avoid taking it.
Protease enzymes in Vital-Zymes™ Complete first cleave intact casein molecule
to split off ␤-casomorphin fragment, an opiate-acting peptide. Enzymes with
DPP-IV peptidase activity then cleave ␤-casomorphin after the first proline linkage
forming di- and tripeptides with no opioid activity.
Statements made herein have not been evaluated by the Food
and Drug Administration. These products are not intended to
diagnose, treat, cure, or prevent any disease.
Well-tolerated, hypoallergenic.
Suitable for children or adults.
• Contains highly purified, pharmaceutical grade enzymes
to meet the needs of sensitive individuals.
• Provides an array of enzymes that encourages maximum
digestion of protein, carbohydrates, sugar, fat, and fiber.
• Free of all maltodextrin (wheat, rice, or corn derived)
commonly used as a base in digestive enzyme supplements.
• Two capsules or chewable tablets effectively support
digestion of a full range of foods as found in a typical meal.
• Avoids fruit derived enzymes (bromelain, papain, and kiwi)
for tolerance by those with pheno-sulfurtransferase issues.
• Readily adjusted for individual needs, including smaller
or larger meals.
Active throughout the GI tract.
• Contains microbial-based enzymes tolerant of a wide
range of pH from 2 (very acidic) to 10 (alkaline), thus
exerting benefit throughout the entire gastrointestinal tract.
• Free of porcine or other animal-derived enzymes that
are easily denatured by stomach acid.
Enzyme Function Chart
Enzyme Type
Enzyme
Amylase, Alpha-Amylase
Carbohydrate-Specific Enzymes
Glucoamylase
Sugar-Specific (Disaccharide)
Enzymes
Maltase
Digests maltose in malt, cereal grains, and processed foods
into glucose
Sucrase (Invertase)
Alpha-Galactosidase
Pectinase
Phytase
Fat-Specific Enzymes
Specialty Enzymes
Converts maltose, maltotriose, and oligosaccharides into glucose
Converts lactose (milk sugar) into glucose and galactose
Cellulase, Hemicellulase
Protein and Peptide-Specific
Enzymes
Converts complex starch in root vegetables and grains into
maltose (a disaccharide), maltotriose (a trisaccharide), dextrins,
and oligosaccharides
Lactase
Pullulanase
Vegetable/Fiber-Specific
Enzymes
Function
Converts sucrose (table sugar) into glucose and fructose; forms
sucrase-isomaltase complex in the intestinal lining that breaks
down dextrins
Breaks down amylopectin starch molecules resistant to degradation
that may otherwise remain trapped in the microvilli and contribute
to inflammation
Liberates nutrients from fruits and vegetables, making them
more bioavailable
Breaks down hard-to-digest carbohydrates found in legumes
and cruciferous vegetables
Hydrolyzes pectin; reduces the bulking effect of some fibrous foods
Breaks down phytates in grains (wheat, oats, barley) and legumes
Beta-Glucanase
Breaks down glucans in cereal grains and in yeast cell walls
Galactomannase
Degrades hemicellulose, cellulose, and cell walls with mannose
Acid and Alkaline Protease
Breaks down plant, vegetable, and meat derived proteins
Peptidase and Dipeptidyl
Peptidase IV (DPP-IV)
Breaks down casein (dairy products) and gluten (wheat, barley, rye)
and their exorphin peptides
Lipase
Hydrolyzes fats in meat and dairy products, oils in nuts and seeds,
and triglycerides
Lysozyme
(highly purified from egg white)
Degrades polysaccharides found in the cell walls of many bacteria,
yeast, and other pathogens
Serratia Peptidase
Breaks down casein protein peptides; breaks down fibrin and
protects sensitive GI tissues from irritation and inflammation
Healthy Digestion: Essential for
Optimum Nutrition and Health.
Almost everyone has experienced digestive discomforts such as gas, bloating,
indigestion, gastric reflux, constipation, or diarrhea at one time or another. Eating the
wrong foods, overeating, undue stress, or intestinal infections are among the
common causes. While such problems are occasional for most of us, impaired
digestion and its adverse health consequences can be frequent and troublesome
problems for others.
When the digestive process malfunctions, malabsorption of nutrients affects overall
health and can potentially lead to intestinal dysbiosis and other unhealthy conditions.
Undigested or partially digested food can putrefy in the gut and produce toxins that
may then leak into the bloodstream, causing fatigue, headache, or behavioral
symptoms. Irritation and inflammation occur, leading to an increase in intestinal
permeability, or "leaky gut." Undigested protein molecules that cross the intestinal
lining may trigger immunological reactions such as allergies, asthma, and skin rashes.
Using Supplemental Enzymes for Maximal Digestive Support.
A healthy digestive system secretes acids and enzymes that break down foods into
the most basic components needed to nourish the body. A variety of different
enzymes, each with unique cleaving actions, are required for optimal breakdown of
foods. Enzyme production is a key part in the digestive process that is especially
susceptible to malfunction. Certain health conditions may adversely affect the body’s
ability to produce its own enzymes, resulting in fewer enzymes or diminished
secretion of enzymes by the pancreas, stomach, and brush-border
membrane of the small intestine.
When endogenous enzyme production is compromised, ingestion of supplemental
enzymes such as protease, amylase, and lipase can help efficiently digest food and
alleviate occasional digestion-related discomforts. However, individuals with more
complex digestive issues may require enzymes with greater specificity to most fully
support digestion of problematic food components such as casein, gluten,
and lactose and other disaccharides and to lessen related irritation
and inflammation in the intestinal tract.
Vital-Zymes™ Complete provides a comprehensive group of
enzymes to specially support individuals with maldigestion,
malabsorption, dysbiosis, and intestinal inflammation.
™
Vital-Zymes Complete
Multi-Enzyme Supplement for
Intensive Digestive Support
• Potent, 20-Enzyme Formula
• Supplies DPP-IV Activity
• Capsule and Chewable Options
• For Children or Adults
• Hypoallergenic
ABOUT PROTHERA®, INC.
ProThera®, Incorporated manufactures a
complete line of nutraceutical products from
the brands healthcare professionals trust and
recommend with confidence. Products
are designed for clinical application and are
available exclusively through healthcare
professionals. Full private labeling and custom
manufacturing services are available.
ProThera®, Inc. is a subsidiary company of
Soho Flordis International Pty Ltd.
OUR BRANDS
SUGGESTED USE
ProThera® brand integrated formulas build
Capsules: Children: 2 capsules per meal or as directed by a physician. Adults: 2 to 4
capsules per meal. Capsules may be opened and contents mixed in a small amount of
food or beverage followed by ingestion of regular food. Should not be mixed with hot
food or beverage as this may reduce enzyme activity. For best results it is recommended
that the enzymes be taken at the beginning of each meal. Dosing should be based on
the amount of foods ingested. Young children may start with 1/3 to 1/2 capsule. Older
children may start with a full capsule per meal. These amounts can be gradually
increased over a period of a week or two to reach the suggested dose.
hypoallergenic pre- and probiotics, enzymes,
Chewable Tablets: Chew 2 or more tablets at the beginning of each meal or as directed
by a healthcare practitioner.
support that can be used with confidence by
ADVERSE REACTIONS
None reported. No upper limit has been established for oral enzyme supplementation.
Animal studies indicate that extremely large doses of enzymes may be ingested without
toxicity or adverse effect. Dosing is based on the amount of food ingested (content and
size of a meal) and not specifically by body weight or age. When mixing capsule contents
in foods, avoid contact with eyes and inhalation of powder as it may cause some irritation
to mucus membranes.
CONTRAINDICATIONS
Large amounts of proteolytic enzymes should not be taken in the absence of normal
gastric mucosa. Do not use if gastritis, peptic ulcer, or heartburn is present. If pregnant
or nursing, consult your healthcare practitioner prior to use. This product may not be
appropriate for those with known allergies to Aspergillus enzyme proteins, though
non-specific mold allergies do not necessarily preclude use of fungal-based enzymes.
Lysozyme is derived from egg white protein and is highly purified. However, this product
may not be appropriate for those with classic allergic reactions (IgE mediated) to egg white.
DRUG INTERACTIONS
Carbohydrases may increase intestinal glucose absorption and may thus interfere with
the efficacy of oral hypoglycemic drugs or insulin.
PRODUCT SUPPLY
upon versatile multiple vitamin/mineral
supplements with focused multi- and
single-ingredient products to address
a variety of metabolic concerns.
Klaire Labs® brand specializes in
and specialty formulas for GI and immune
individuals who are hypersensitive to various
foods and environmental agents.
Complementary Prescriptions™ brand centers
on a modular concept that utilizes foundational
products for total wellness, protocol formulas for
targeted support, and synergistic
antioxidants, hormones, and energizers to
create effective anti-aging programs.
CONTACT US
888-488-2488 • www.protherainc.com
10439 Double R Blvd, Reno, NV 89521
ProThera®, Inc. operates a GMP 9000
registered facility certified by NSF®
International, an independent, third-party
certification organization. GMP 9000 registration
integrates both ISO 9001 and GMP registration.
Vital-Zymes™ Complete: 120 vegetarian capsules per bottle.
Vital-Zymes™ Chewable: 180 chewable tablets per bottle.
Statements made herein have not been evaluated
by the Food and Drug Administration.
These products are not intended to diagnose,
treat, cure, or prevent any disease.
Order Today!
888-488-2488 • protherainc.com
Available exclusively through licensed healthcare professionals.
Free, 2-day private labeling with 12-bottle minimum order.
©Copyright 2007-2015
ProThera®, Inc.
Reno, NV
All rights reserved.
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