NEWSLETTER - American Society for Cell Biology

Transcription

ASCB
JANUARY/FEBRUARY
2011
NEWSLETTER
VOLUME
ASCB’s
Increasing Value
Page 3
Annual Meeting
Highlights
Page 21
Hone Your
Grantsmanship
Page 49
Inside
President’s Column
3
Committee Reports
11
MBoC Gets New Look
13
Fawcett Memorial Awards
19
Annual Meeting Highlights
21
Videotaped Lectures
34
MAC Funding Available
38
Exhibitor Advisory Committee 40
Public Policy Briefing
41
Call for Nominations
43
Highlights from MBoC
44
ASCB Press Book
46
Letter to the Editor
48
WICB Column
49
Dear Labby
51
Meeting Supporters
52
Corporate Members
54
Member Gifts
54
2010 Half-Century Fund Donors54
New ASCB Members
55
ASCB Emeritus Members
59
Grants & Opportunities
60
Members in the News
62
In Memoriam
62
Did You Know...?
62
Calendar
62
34,
NUMBER
1
Meeting a Rousing Success,
Memories Live On
The 50th Anniversary ASCB Annual Meeting is over, but
the memories remain… while the reviews are still coming
in! Many of the record-number travel awardees wrote in awe
of the meeting’s breadth and depth. It gave them a muchappreciated opportunity to learn new techniques, present
their research, and gain valuable feedback.
Annual Meeting survey respondents pointed to the
incredible networking and exciting science they heard.
Career sessions were invaluable and popular. Particular
Susan Baserga looked through a
thrills cited: hearing ASCB speakers talk about their
microscope used by Keith R. Porter.
successes and hardships (with some conversations to air on
The microscope and ASCB historical
YouTube), and senior scientists offering feedback to poster
documents were on loan from the
University of Maryland Baltimore County,
presenters and Science Discussion Table participants. In
Albin O. Kuhn Library & Gallery.
fact, National Institute of General Medical Sciences blogger
Joe Gindhart noted that “each [Science Discussion] table was crowded with graduate students
Annual Meeting 2010, continued on page 5
ASCB Council Ponders
Strategy, Sets Goals
Where is cell biology going? That was the question 2010
ASCB President Tim Mitchison posed to the ASCB Council
and staff at the December 10–11, 2010, ASCB Council
Meeting in Philadelphia.
“We have to think about who are we and how we get
[where we want to go],” Mitchison noted. “There’s not
unanimity regarding how much we should be using cell
biology to cure disease, but we need to think about how we
position ourselves for the future.”
Current Value, Future Potential
Then President-Elect Sandra Schmid expanded Mitchison’s
call to the ASCB Council: “We need to be an essential part
of a teacher’s education, [essential] for postdocs, assistant
professors, associate professors, industry.” In 2010 Council
revised the ASCB mission and goals, guided by input from
members, committees, and staff. She noted the current need
to “dig down” to get to objectives and action steps.
Executive Director Joan Goldberg emphasized ASCB’s
strengths—including innovation and commitment. A lively
Council Report, continued on page 7
2010 ASCB President Tim Mitchison
passed the gavel to 2011 ASCB
President Sandra Schmid.
This will be your
last issue of the
Newsletter…
... if you haven’t paid your
2011 dues. Renewing is easy.
Go to www.ascb.org: click on
“Membership” and then on
“2011 Dues Renewal Online.”
Forget your username or
password? Contact us today at
[email protected]. n
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PRESIDENT’S Column
The Essential ASCB: A Community
for Cell Biologists
Twenty years ago I attended my first ASCB
meeting as a newly minted assistant professor.
I had been invited to chair a Minisymposium
on endocytosis, and I was being given the
Women in Cell Biology (WICB) Junior Career
Award. The former was my first opportunity
to be seen as a leader in my
chosen field. The latter offered
a challenge: The award was
inscribed “In recognition of
her significant potential for
scientific achievement.” In
one meeting the ASCB had
both acknowledged my efforts
to that point and created the
expectation for me to do more.
History has repeated itself. I
am grateful that by electing me
as President you, the members
of ASCB, have recognized my
Sandra Schmid
leadership in cell biology. But I
also accept your challenge for more.
For 50 years the ASCB has been fulfilling
its original mission of “promoting the field of
cell biology.” At the 50th Anniversary Keynote
Symposium I had the honor of meeting many of
the distinguished past presidents whose efforts
over the past five decades, together with those
of legions of volunteer committee members and
our dedicated professional staff, have made the
ASCB the influential and vibrant organization
it is today. In keeping with the theme of this
essay, while acknowledging all that the ASCB
has accomplished to this point, I also bring high
expectations for increased value.
Valuable ASCB Activities
Last year, as President-Elect, I initiated a longterm strategic planning effort that started with
assessing who we are and what we do.1 Through
numerous discussions with Council members
and committee chairs, analysis of membership
surveys, and knowledgeable input from ASCB
staff, I have been made even more aware of the
incredible diversity and value of the ASCB’s
activities. For example:
n Did you know that as a founding member of
the Coalition for the Life Sciences the ASCB
was instrumental in securing the doubling of
JANUARY/FEBRUARY 2011 ASCB NEWSLETTER
the National Institutes of Health budget that
occurred in the late ’90s? The Public Policy
Committee of the ASCB has also taken the
lead in standing up against anti-evolutionists
and for stem cell research. These issues go to
the heart of our greater society’s support for
the scientific/research enterprise.
n Did you know that the
discoveries highlighted in
the Public Information
Committee (PIC) press
book are picked up and
disseminated in newspapers,
journals, and magazines
throughout the country? The
PIC works tirelessly to inform
the public of the value and
excitement of our research.
n Did you know that our
journal CBE—Life Sciences
Education (CBE-LSE ) has
become the leading journal in its field?
The Education Committee, through other
activities, along with CBE-LSE, points K–12
and undergraduate educators to researchtested, inquiry-based approaches. These efforts
not only ensure a steady stream of future
cell biologists, they also raise overall public
awareness of the scientific method and its value.
n Did you know that the ASCB has a very
active International Affairs Committee
(IAC), something that many societies lack?
Our IAC reaches out to colleagues across the
globe and supports training and research in
the developing world, including India and
Africa, as well as international collaboration.
n Did you know that no other single
scientific society can match the efforts of
our Minorities Affairs Committee (MAC)
to increase and maintain diversity within
the research community? Over the years,
generously supported by a Minority Access
to Research Careers grant from the National
Institute of General Medical Sciences, MAC
has provided opportunities for training,
networking, scientific exchange, research,
recognition, and mentorship to countless
underrepresented minority scientists at all
stages of their careers.
The American Society
for Cell Biology
8120 Woodmont Avenue, Suite 750
Bethesda, MD 20814-2762, USA
Tel: 301-347-9300
Fax: 301-347-9310
[email protected], www.ascb.org
Joan R. Goldberg
Executive Director
Officers
Sandra L. Schmid
President
Ronald Vale
President-Elect
Timothy J. Mitchison Past President
Thoru Pederson
Treasurer
Jean E. Schwarzbauer Secretary
Council
David Botstein
Raymond J. Deshaies
Joan R. Goldberg, ex officio
Akihiro Kusumi
Inke Näthke
James H. Sabry
David L. Spector
Elizabeth Sztul
JoAnn Trejo
Fiona M. Watt
Susan M. Wick
Virginia A. Zakian
Yixian Zheng
The ASCB Newsletter
is published 11 times per year
by The American Society
for Cell Biology.
Joan R. Goldberg Editor
W. Mark Leader
Editor
Elizabeth M. Rich Production Manager
Kevin Wilson Public Policy Director
John Fleischman
Science Writer
Thea Clarke
Editorial Manager
Advertising
The deadline for advertising is the
first day of the month preceding the
cover date. For information contact
Advertising Manager Ed Newman,
[email protected].
ASCB Newsletter
ISSN 1060-8982
Volume 34, Number 1
January/February 2011
© 2011 The American Society for Cell
Biology. Copyright to the articles is held
by the author or, for staff-written articles,
by the ASCB. The content of the ASCB
Newsletter is available to the public under
an Attribution-Noncommercial-Share Alike
Unported Creative Commons License
(http://creativecommons.org/licenses/
by-nc-sa/3.0).
Postmaster: Send change of address to:
ASCB Newsletter
The American Society for Cell Biology
3
Did you know that many other societies look demonstrate to ourselves and others exactly how
essential this organization is. Here are some
to our WICB Committee as a model for
promoting and supporting women in science specific goals:
through advocacy, career
n To improve communication,
development guidance,
Council has pledged to hold
[T]he many
networking opportunities,
more frequent conference
calls. The Executive
recognition, a speakers
activities of the
Committee will more
bureau, and more?
ASCB constitute
n Finally, did you know that
frequently invite individual
the ASCB Annual Meeting
committee chairs to discuss
the essential
is the largest gathering of cell
their committee’s activities.
infrastructure
biologists in the world? Our
Such conversations often
Annual Meeting provides
lead to new ideas and reveal
needed to support
a unique opportunity to
opportunities for synergy
and enrich... our
and integration across
experience both the breadth
careers. [L]ike the
our many programs. For
and depth of cell biology. It
example, the idea for the
is a venue not only for our
heat and lights in
most distinguished scientists,
highly successful Science
our laboratories...
but also for undergrads,
Discussion (networking)
graduate students, postdocs,
Tables during the poster
we tend to take
and junior faculty to present
sessions at the 2010 Annual
[them] for granted.
their work. And it’s an
Meeting arose during one
such Council phone call.
unprecedented opportunity
We forget how
for networking across all
n To improve communication
critical the right
career levels.
with and among our
environment can
members, we will begin
Creating
to expand our Member
be for boosting
Opportunities through
Directory and create a
our careers and
Communication
dynamic and searchable
In a sense, the many activities
database linking members
productivity.
of the ASCB constitute
by research interests and
the essential infrastructure
expertise, primary
needed to support and enrich both our chosen
methodologies, teaching obligations,
profession and our individual careers. Sadly, like
available positions, etc. With your help and
the heat and lights in our laboratories and the
input, this expanded Member Directory will
journals in our libraries (or on our intranets),
enable potential postdoctoral fellows and/or
we tend to take these activities for granted. We
collaborators to identify regionally specific
forget how critical the right environment can be
opportunities for collaboration, positions,
for boosting our careers and productivity. The
and networking more readily. Importantly,
ASCB functions to create such an environment,
the database will also enable the ASCB to
but we can be even more effective. This year
communicate with its members and serve
my efforts will be focused on putting in place
their needs more effectively. And future
mechanisms for more effective, multidirectional
Program Committees and other ASCB
communication within the organization, both
members who organize meetings will be
between the ASCB and its members and among
able to draw on information in the database
its members.
to identify speakers. These efforts will
My goal is to work with Council and
supplement and extend those of WICB’s
the ASCB staff to strengthen the ASCB as a
Speakers Bureau; WICB offers a service
community by increasing opportunities for
for all meeting organizers that showcases
networking, collaboration, career development
female scientists by specialty. (For more
and promotion, education, and scientific
information, write [email protected].)
exchange—all essential components for
n To continue to use this President’s Column
successful careers. If we seize the opportunity
as a vehicle to discuss matters of concern
to communicate more effectively, then we can
to our community of cell biologists. I plan
n
This year my efforts
will be focused on
putting in place
mechanisms for
more effective,
multidirectional
communication
within the
organization, both
between the ASCB
and its members
and among its
members.
4
ASCB NEWSLETTER JANUARY/FEBRUARY 2011
to be provocative and, by doing so, hope to
and the depth of cell biology, promoting
and leading discussions on future trends
start some conversations that can continue
and challenges in cell biology,
in our labs and departments,
in the Newsletter, and at our
and by providing increased
[Our goal is to make opportunities for scientific
meetings.
n To overhaul and update the
exchange, networking, and
the ASCB website]
career development.
ASCB website so as to make
your essential
I love a challenge, but I’ll
it your essential bookmark
for research highlights and
need
your help to accomplish
bookmark for
these goals. Be part of the
opportunities, career advice,
research highlights
community and add to the
networking, educational
and opportunities,
conversation. Let me know
and training tools, shared
your
ideas about how the
protocols, job postings,
career advice,
ASCB is or can be essential
etc. We’ll add to the tons
networking,
for cell biologists at all stages
of information already
of their careers. I’m looking
available, and better organize
educational and
forward to a great and
it to make it more readily
training tools,
productive year! n
searchable and accessible
according to your interests.
shared protocols,
Comments are welcome and
We’ll create a more dynamic
job postings, etc.
should be sent to president@ascb.
and interactive site to let
org.
you know better what we’re
doing and how we can help
Reference
each other.
1
n To increase the unique value of the ASCB
Schmid S (2010). A vision for cell biology. ASCB
Annual Meeting by showcasing the breadth
Newsletter 33(4), 3–4.
Annual Meeting 2010, continued from page 1
and postdocs eager to discuss science and seek
advice from their fields’ leaders.… I wish that
there had been these tables when I was a young
scientist….” Table leaders reported similar
satisfaction with ASCB’s latest innovative
offering. ASCB’s first Graduate School Fair was
also enjoyed by participants and presenters alike.
For more information about 2010 Annual
Meeting sessions, including some available on
videotape to ASCB members (see list on p. 33),
visit www.ascb.org and click “Members Only,”
then “Multimedia Content (Video/PPT slides).”
To view the press book, go to www.ascb.org/
pressbook/2010/embargo/pressbook.html. Or
enjoy essays from 2010 ASCB award recipients
and from leading scientists about the future
of cell biology in Molecular Biology of the Cell
(MBoC ) at www.molbiolcell.org/content/vol21/
issue22. (Coverage of Minisymposia will appear
in the March 15, 2011, issue of MBoC.)
For visual highlights, don’t miss the winning
Celldance videos and images, presented in
Philadelphia at what the New Scientist called
“Biology’s answer to the Oscars” (http://ascb.
ascb.org/meetings/celldance_winners.cfm).
Rapt participants at a Science Discussion Table
Celebrate the ASCB’s 50th anniversary by
visiting www.ascb.org/50thanniversary.html.
And look to the future as predicted by Annual
Meeting participants on p. 9, cited by Faculty of
1000 as a display of comparable interest to our
featured talks and displays.
Partial to the science? Ginhart noted, “I
saw a number of outstanding talks and posters
at the meeting, and to say that there is not
enough room here to mention them all is an
understatement.” Like Gindhart, we’re “already
looking forward to the 2011 meeting in
Denver.” n
—Joan R. Goldberg
5
ASCB Council Report
Council Report, continued from page 1
Council discussion followed about moving forward
and building on the ASCB’s opportunities.
Taking Care of Business
ASCB Director of Finance & Administration
Cynthia Godes reported that the value of ASCB’s
investments increased 15% in 2009 from
2008. ASCB investment value is 84% of 2010’s
budgeted expense; 60% is the target, she noted.
Goldberg reported the largest number of
membership applications since June ever. In
2010 membership rose 1.3% from 2009,
and Council removed several barriers to
membership: approving new members monthly
and eliminating the sponsorship requirement. In
2011 ASCB will offer three-year memberships;
staff will consider how lifetime and 10-year
memberships might be implemented.
Promoting Scientific Discovery
Council and members perceive the ASCB Annual
Meeting (AM) as a tremendous strength, and
a premier way to promote discovery—ASCB’s
primary goal. “The Meeting is not just about
Symposia and Minisymposia. Other formats
allow for more members to participate,” 2010
Program Committee Chair Jodi Nunnari noted.
Council discussed the 2011 AM program
and the continuing focus on core cell biology—
the area in which members most preferred
expansion in ASCB’s 2010 survey. Goldberg and
then Council member Kathy Green questioned
annual Program Committee turnover and lack
of Council consensus regarding the AM core
content. Areas of strength and focus shouldn’t
be forgotten, Green added. Council member
Elizabeth Sztul suggested that Council discuss
a three- to five-year AM plan. Schmid will
establish a Council subcommittee to focus on
the AM longer term. For continuity, Council
voted to add two Councilors to the Program
Committee.
Council also discussed with Caroline Kane,
PI of the ASCB’s National Institute of General
Medical Sciences (NIGMS)-funded grant in
support of The Cell: An Image Library. They
discussed progress and added emphasis on
educational use. Kane noted that the Library’s new
license options allow image uploads from journals
in compliance with their policies. When the twoyear American Recovery and Reinvestment Act
grant ends in August 2011, ASCB will request
a no-cost extension. Kane reported that she is
2010 ASCB Council meeting attendees, left to right, front row: Holly
Goodson, David Spector, 2011 President Sandra Schmid, 2010 President
Tim Mitchison, 2009 President Brigid Hogan, Kathleen Green, Clare
Waterman; back row: Yixian Zheng, Susan Wick, Akihiro Kusumi, David
Botstein, Raymond Deshaies, JoAnn Trejo, Virginia Zakian, Secretary Jean
Schwarzbauer, Elizabeth Sztul, 2011 President-Elect Ronald Vale, James
Sabry, ASCB Executive Director Joan Goldberg
discussing future funding with various entities.
The Library needs contributions and user
feedback, Kane concluded.
One important way that the ASCB promotes
scientific discovery is by publishing Molecular
Biology of the Cell (MBoC). MBoC Editor-inChief David Drubin told Council of his goals for
the journal: making the best possible product,
increasing its profile, and better integrating it with
the ASCB. Drubin believes there is opportunity
for synergism between MBoC and the ASCB in
achieving many of the Society's goals.
Advancing Sound Research
Policies
Then Chair of the Public Policy Committee
(PPC) Tom Pollard, an ASCB past president,
reported:
n Advocacy is probably the lifeline of the
Society, to maintain the standard of support
in the future that we’ve had in the past.
n PPC efforts are augmented by that of the
Coalition for the Life Sciences (CLC,
formerly the Joint Steering Committee);
ASCB is a founding member.
n CLS’s Biomedical Research Caucuses are
going into their 20th year and are well
respected on Capitol Hill, educating
Representatives and their staff.
Goldberg noted that the PPC, like other
ASCB committees, doesn’t have clear goals or
objectives in the ASCB Bylaws. The Council
needs to discuss with committees questions
related to specific goals, such as:
n What would success look like? (For PPC:
More funding for basic research or staying
stable? What is realistic?)
2010 Council
Timothy J. Mitchison,*
President
Raymond J. Deshaies*
Joan R. Goldberg,* ex officio
Holly V. Goodson*
Kathleen J. Green*
Brigid Hogan,* Past President
Inke Näthke
Thoru Pederson, Treasurer
Sandra L. Schmid,*
President-Elect
Jean E. Schwarzbauer,*
Secretary
David L. Spector*
Paul W. Sternberg
Elizabeth Sztul*
JoAnn Trejo*
Clare M. Waterman*
Fiona M. Watt
Susan M. Wick*
Virginia A. Zakian*
2011 Incoming
Council
David Botstein*
Akihiro Kusumi*
James H. Sabry*
Ronald Vale,* President-Elect
Designate
Yixian Zheng*
*In attendance at December
meeting
7
ASCB Council Report
Do younger members know how important
advocacy (or better teaching/curricula or
public information) is for their future?
Shouldn’t they? How do we ensure this?
Goldberg noted that 23% of ASCB members
join the Society for advocacy, while 36%
remain members
for it. Seventy Keynote Address
seven percent
rated outreach
to Congress as
either “very”
or “somewhat”
important in
ASCB’s 2010
member survey,
Left: Gary Borisy gave Keynote remarks about the Society’s
she added. Support
accomplishments during the past 50 years; right: Keynote
must be translated
Speaker Tim Mitchison presented a certificate of appreciation to
into action, she and
2010 ASCB Program Committee Chair Jodi Nunnari. Videotape
available, see p.34.
Pollard emphasized.
Nunnari
pointed to concerns about the limited number
of U.S. National Institutes of Health (NIH)
study sections accepting cell biology grants;
maybe members need advice about how to
submit grants. The Society mentors minority,
young faculty, and postdoc members regarding
grant submission in a summer junior faculty
workshop and at the ASCB Annual Meeting.
An expanded effort may be in order, Council
discussed, as well as whether PPC should reexamine study section composition.
n
Increasing Diversity in the
Scientific Workforce
Minorities Affairs Committee (MAC) Chair
Renato Aguilera reported:
n A record number of MAC travel awardees
this year—92!
n Many participating in the Minorities Poster
Session wouldn’t do so without ASCB
(from NIGMS Minority Access to Research
Careers, or MARC, grant) funding.
n The Junior Faculty Workshop also assists
postdocs and is highly evaluated, like other
MARC-funded programs.
Council discussed expanding the MAC,
perhaps with individuals who have training
grants. Senior Manager, Minorities Affairs,
Deborah McCall noted that the MAC is also
establishing a pilot mentorship program,
focused on grant writing.
Women in Cell Biology (WICB) Committee
Chair Sandy Masur reported:
8
WICB programs are aimed at women
and men to provide opportunities and
information useful for career development.
n Biotech is the most popular of the
WICB Career Discussion and Mentoring
Roundtables; WICB will consider a separate
AM session on this.
n Childcare awards to further AM attendance
numbered 15 in both the first and second
years, and 40 this year!
n WICB’s Speaker Referral Service (www.ascb.
org/index.php?option=com_content&view=
article&id=94&Itemid=147) is a challenge.
(At Masur’s suggestion, WICB subsequently
received a list of past ASCB female speakers
to help with referrals.)
Council discussed how requiring member
specialties for the Member Directory will provide
an excellent resource. Brainstorming about other
membership benefits led Council to discuss
expanding the AM focus on job openings and
interviews.
n
Improving Education
Education Committee (EdComm) Chair
Kane reported the goals set by the Committee:
promoting science literacy, honoring and
educating educators, and educating students at
the K–12, undergraduate, graduate, and postdoc
levels. The Graduate School Fair is new in 2010,
she said. Thirty-one graduate departments
registered, Senior Editorial and Education
Manager Thea Clarke noted. The Undergraduate
Reception featured about 80 posters. Council
discussed other EdComm activities and
undergraduate biology education issues.
Public Information Committee (PIC) Chair
Rex Chisholm noted:
n ASCB’s press book, Cell Biology 2010
(www.ascb.org/pressbook/2010/embargo/
pressbook.html) helps ensure public
education about cell biology (and can be used
in the classroom).
n The Celldance image and video contest
conveys ASCB’s sense of humor and
showcases creativity.
n The first Conversations session—held in
2010—edited for YouTube.
CBE—Life Sciences Education Editor-inChief Erin Dolan gave an overview of the focus
of ASCB’s education journal. She noted that the
journal is aiming to be the go-to journal for life
scientists regarding education research and practice.
It will continue to publish innovative, evidenceASCB NEWSLETTER JANUARY/FEBRUARY 2011
ASCB Council Report
based research and evaluation in education.
Council noted support from the Howard Hughes
Medical Institute through December 2011 and
considered new business models.
International Affairs Committee (IAC) Chair
Jim Spudich, an ASCB past president, noted his
desire to connect with other societies’ IACs and
the IAC’s goals of enhancing engagement in the
Society, outreach and promotion of international
exchange, and building capacity worldwide. He
gave an overview of IAC programs, including the
first International Research & Training Exchange
Fair, outreach to specific countries, African
Meeting Attendees Predict
Scientific Discoveries in
the Next 50 Years
workshops, the Books for Africa initiative,
iBioSeminars, and iBioMagazine.
Next Steps
Then President-Elect Designate Ron Vale noted
that emphasizing the value ASCB provides yearround is important. Focusing more on mentorship
and career assistance through the Web is critical.
The Council discussed prioritizing goals and
approved hiring a communications professional
(see p.17) to help develop and implement an
improved communications plan. n
—Joan R. Goldberg
ASCB Annual Meeting Attendees
2010–2019
n
n
n
n
n
n
Epigenetic cancer drugs
Identification of what “junk” DNA does
1 nm resolution light microscopy
High content screening
Digital displays for posters
Full human delivery of siRNA
2020–2029
n
n
n
n
n
n
n
John Heuser, Morris & Shirley Karnovsky
Vivian Siegel
HIV vaccine
Cure for ADD/ADHD
Bioartificial organ
Protein folding solved
First human clone
Nanocrystalline buildings from cells
Drug that replaces need for sleep
2030–2049
n
n
n
n
n
n
n
Organ regeneration
Algae as biofuel for automobiles
Cure for the common cold (antivirals)
Plant life that can be fully sustained
during extreme climates
No more world hunger
Human blood factories
Limb regeneration for amputees
Xiaolan Fang at her poster
Poster viewers in the Exhibit Hall
2050–2060
n
n
n
n
n
Memory mechanisms
Artificial life in laboratory
Key molecule that causes sudden death in
aged individual
Ability to scientifically model and predict
human behavior
Computer small enough to be implanted
in your brain
Porter lecturer Tom Rapoport
Jean-Paul Revel, Tim Mitchison, Paul Nurse
9
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ASCB COMMITTEE Reports
CBE-LSE Board: Enhancing
Content, Assessing Impact,
Seeking Support
New Editor-in-Chief Erin Dolan chaired her
first Editorial Board Meeting of CBE—Life
Sciences Education (CBE-LSE) in December.
Dolan, from Virginia Tech, took over from Bill
Wood on August 1, 2010.
The Board discussed upcoming
enhancements to the journal:
n Beginning in 2011, the journal will solicit
an annual essay from the winner of the
ASCB Bruce Alberts Award for Excellence
in Science Education. Other outstanding
education awardees will be acknowledged at
the end of the essay.
n CBE-LSE will solicit a series of essays on
research methodologies.
In assessing CBE-LSE ’s impact, the Board
noted that:
n Journal usage statistics for 2010 closely
followed those of 2009.
n The journal’s first Thomson Reuters impact
factor should be released in May or June
2011.
Documenting the journal’s impact is
important as ASCB seeks new and renewed
funding for CBE-LSE. Partial funding from a
Howard Hughes Medical Institute (HHMI)
grant ends on December 31, 2011. Dolan
and journal staff will begin to document the
types of impact the journal has had on people
professionally and on their teaching practice,
annual evaluation, promotion, and tenure.
ASCB will apply to HHMI for continued
funding of the journal, and will also try to
identify additional funding sources.
The Board noted the success of the special
issue devoted to the mutualism of biology and
mathematics, which was published online in Fall
2010. It may be possible to secure funding from
a philanthropic source for printing the special
issue.
2010 ASCB President Tim Mitchison
presented Wood with an etched crystal award to
thank him for his years of service to the journal.
Wood will remain on the Board as a Senior Editor.
—Thea Clarke
Education Committee:
Brainstorming about Mission,
Future Programs
Last month in Philadelphia members of the
ASCB Education Committee (EdComm)
heard from Karen Dell, who presented
information about the ASCB education
initiatives iBioSeminars (www.ibioseminars.
org) and iBioMagazine (www.ibiomagazine.
org). Dell works with ASCB President-Elect
Ron Vale on the free, on-demand video
projects. She requested EdComm members
to look at the sites, tell colleagues about
them, and provide feedback. Dell noted
that iBioSeminars now includes 56 lectures
aimed at the advanced undergraduate and
graduate student level. Some of the lectures
have been expanded to include teaching
tools and shorter video clips. iBioMagazine
is a collection of 15-minute talks intended
to show the more human side of science,
and feature career advice. iBioMagazine goes
“behind-the-scenes” of scientific discoveries,
provides advice for young scientists, and
explores how research is conducted in the life
sciences.
Members also discussed the Committee’s
mission and goals. Work is continuing on a
mission statement, which will be discussed in
more detail in a February conference call.
The Committee is pleased to welcome
Martha Cyert, Stanford University, and
Cheston Saunders, soon to be a graduate
student at Syracuse University, as new
members. In addition, three new Associate
members (Lena Diaw, National Institutes of
Health; Melissa Marcucci, St. Joseph College;
and Diana Speelman, Stevenson University)
will help update the ASCB’s BioEDUCATE
website.
—Thea Clarke
2010 Education
Committee
Caroline Kane,* Chair
Alison E.M. Adams
Jennifer Chua,* ad hoc
Shubhik K. DebBurman
Erin Dolan,* ex officio
Kyle Draheim,* ad hoc
Joel M. Goodman*
Karen E. Kalumuck
Anthony J. Koleske*
Elisa M. Konieczko*
Fran Norflus*
George E. Plopper, Jr.*
Jerry W. Reagan, Jr.*
Kathy T. Schmeidler*
Kimberly D. Tanner
William Wallace*
Susan M. Wick*
Michael J. Wolyniak*
William B. Wood,* ex officio
Robin L. Wright*
meeting
11
2010 International
Affairs Committee
James A. Spudich,* Chair
Bruce M. Alberts*
Mary C. Beckerle
Kirk W. Deitsch
Karen D. Dell*
Nina Dudnik,* IAC Associate
Cynthia G. Jensen
Judith Kimble
Deborah Lycan*
Vivek Malhotra, IAC
Associate
Satyajit (Jitu) Mayor*
J. Richard McIntosh*
John Mercer,* IAC Associate
Mahasin A. Osman*
Mark Peifer*
David S. Roos*
Jonathan M. Scholey
Margaret A. Titus
Shubha Tole
Ronald Vale*
Christopher D. Watters
meeting
2010 Minorities
Affairs Committee
Renato J. Aguilera,* Chair
David J. Asai*
David Burgess,* MARC
Grant PI
Andrew G. Campbell*
Franklin A. CarreroMartinez*
Wilfred F. Denetclaw Jr.*
Deborah Harmon Hines
Tama W. Hasson*
Michael J. Leibowitz*
Veronica Lopez,* Postdoctoral
Fellow
Sandra A. Murray*
Sue Shafer*
Winston Thompson*
MariaElena B. Zavala*
meeting
12
International Affairs Committee:
Evaluating Annual Meeting Events
and Planning New Projects
Chair Jim Spudich led lively discussions during
the International Affairs Committee’s (IAC’s)
December meeting held in Philadelphia. Topics
discussed included:
n Popularity of the yearly IAC Roundtable for
U.S. and international graduate students and
postdocs
n Development of the new International
Research & Training Exchange Fair for future
Annual Meetings
n Success of the 2010 workshops held in Accra,
Ghana, and Dar es Salaam, Tanzania, funded
by a grant from the Carnegie Foundation of
New York
n Strategies for supporting and seeking funding
for international meetings and development
of a mission plan
n Introduction of iBioMagazine, an offshoot
of iBioSeminars, which contains 5- to
10-minute talks, focuses on the human
side of cell biology, and spotlights scientists
behind the scenes
n Possibility of cell biologists traveling to India
to teach courses
n Further outreach to South America
n Collaboration with Seeding Labs
—Cheryl Lehr
Minorities Affairs Committee:
Celebrating Record MAC Travel
Awards and Poster Presenters at
the 2010 Annual Meeting
Excited about a record number of travel
awardees and poster presenters at the 2010
Annual Meeting, the Minorities Affairs
Committee (MAC) met in Philadelphia. The
MAC was able to support more awards with
its significantly larger ASCB Minority Access
to Research Careers (MARC) grant from the
National Institute of General Medical Sciences
(NIGMS). Annual funding is over $800,000.
Guests at the meeting included then ASCB
President-Elect Sandra Schmid and MAC
Evaluator Joy Quill. Schmid thanked MAC
Chair Renato Aguilera and the Committee
for their hard work throughout the year. Quill
reported that MAC programs continue to
receive high ratings and that MAC support is
U.S. and international students and postdocs at IAC’s
Roundtable
vital for many awardees. Without the awards,
many would not be able to attend courses,
workshops, and other MAC programs. Staff at
the meeting included ASCB Executive Director
Joan Goldberg and Senior Manager, Minorities
Affairs Deborah McCall.
Guest Karen Dell, with iBioSeminars,
attended a portion of the meeting. iBioSeminars
is looking for more minority presenters for its
online seminar programming and assistance
with disseminating and advertising iBioSeminars
and iBioMagazine. The Committee
recommended past E.E. Just Awardees as
possible iBioSeminars speakers and will share
program information with MAC awardees.
The Committee discussed its ongoing
and expanded programs: the MAC Visiting
Professorship, Linkage Fellowships, Travel
Awards, the new MAC Mentoring Program,
the Marine Biological Laboratory and Friday
Harbor Laboratories Programs, and the
Annual Biomedical Research Conference for
Minority Students (ABRCMS) and Society
for Advancement of Chicanos and Native
Americans in Science (SACNAS) activities. All
programs are supported by MAC’s longstanding
NIGMS/MARC grant. MARC Grant PI David
Burgess reported that the MAC’s carryover
request was approved by NIGMS and that
MARC Year 14 program spending is on track.
The MAC also discussed openings for new
members and its desire to increase the MAC’s
size. Aguilera reported that with MAC’s growth,
additional MAC members are needed to assist in
running the programs.
The MAC was pleased with its ASCB Annual
Meeting programming this year in Philadelphia
and looks forward to planning another exciting
program for Denver in 2011.
—Deborah McCall
MBoC Board: Serving Science and
the ASCB
Seventeen new members have been added to
the Board of Reviewing Editors.
Edelstein-Keshet and Mogilner are both
“What can we do with this journal to make it
theoreticians,
and their appointment to the
as useful as possible for our community?” asked
MBoC
Board
underscores
the journal’s strong
Molecular Biology of the Cell (MBoC) Editor-ininterest
in
modeling
papers.
The topic of
Chief David Drubin at the 2010 Editorial Board
the
2010
MBoC-sponsored
Annual
Meeting
meeting held in December in Philadelphia. He
workshop—“Will
Mathematical
Modeling
noted that as an ASCB journal, MBoC has some
unique opportunities. Board members discussed Help Your Manuscript?”—also reflected this
interest. Several Board members commented
ways in which MBoC can emphasize and
strengthen its ties to ASCB and innovations that on the difficulty some authors have in finding
an appropriate journal for papers that combine
would be of service to readers and authors.
theory and experiment and suggested that
Drubin pointed out several recent and
MBoC can provide a valuable service as a venue
upcoming efforts to serve ASCB members and
for such work.
reinforce MBoC ’s connection with the Society:
The Board also discussed:
n Publication of a special issue in celebration of
n
The role of MBoC Technical Perspectives in
ASCB’s 50th anniversary
establishing criteria for research in the field
n Publication of ASCB Annual Meeting
of cell biology. (The first MBoC Technical
abstracts in MBoC
Perspective, by Tom Pollard, was published
n Upcoming coverage of ASCB Annual
in the December 1, 2010, issue and entitled
Meeting Minisymposia (scheduled for the
“A Guide to Simple and Informative Binding
March 15, 2011, issue)
Assays.”)
n An MBoC-sponsored workshop at the Annual
n
Additional features that can be added when
Meeting
the journal’s website is redesigned in mid-2011
Drubin noted some changes to the Board:
n
Possible synergy with CBE—Life Sciences
n Tim Stearns has stepped down as Associate
Education and the ASCB Newsletter
Editor.
n
The value of helping authors with
n All other Associate Editors whose terms
constructive peer review and editorial
ended in 2010 have agreed to stay on.
suggestions
n Recent additions to the Board include
Drubin thanked Board members for their
Associate Editors Leah Edelstein-Keshet,
efforts
and urged them to spread the word
Martin Hetzer, Alex Mogilner, and Elly
about
what
a great job the journal is doing.
Tanaka.
He mentioned, for example, that the journal
turns manuscripts around really
rapidly. The average time from
receipt to final decision in 2009
was only 58 days.
—W. Mark Leader
Beginning with its January 1, 2011, issue Molecular Biology of
the Cell (MBoC) boasts a new
Public Information
design. The logo and cover
Committee: Changing
have been updated, as has the
PDF presentation of articles.
and Evolving
The new look incorporates
The Public Information
a new, sans serif typeface,
Committee (PIC) changed its
new table design, simplified
Chair at its December meeting
reference formatting, and
in Philadelphia. Rex Chisholm,
other features intended to
Chair of PIC since 2004,
make articles more attractive
stepped down, ending an 18and easier to read.
year involvement with ASCB’s
MBoC ’s website will be
public outreach efforts. The new
redesigned later in 2011.
Chair, Simon Atkinson, took
the reins as PIC continues its
n
2010
Public Information
Committee
Rex L. Chishom,* Chair
Simon Atkinson,* Vice Chair
Scott D. Blystone*
Lynne Cassimeris*
Duane A. Compton*
Thomas T. Egelhoff*
Lee Ligon*
Kathleen G. Morgan*
Gregory Payne
Deepti Pradhan*
Nava Segev
Kenna Mills Shaw
Kip Sluder*
Margaret A. Titus*
Kathy Wilson*
meeting
MBoC Gets New Look
13
Live cell imaging can be challenging. But Olympus
innovation eliminates its inherent complexities and makes
capturing and then viewing images easier than ever.
• VivaView®—Simplifies long-term, high-content live cell
imaging by engineering high-performance optics into a
tissue-culture-grade incubator
• cell^TIRF™ illuminator—Simplifies multicolor TIRF
imaging with a software interface that provides digital
control of up to 4 wavelengths simultaneously
• IX81®-ZDC2—Simplifies time-lapse experiments with a
high-speed mechanism designed to prevent focus drift
• FluoView® FV10i—Simplifies confocal imaging as the
world’s first, self-contained laser-scanning microscope
with a footprint so small it fits on a lab bench
See it for yourself • olympusamerica.com/livecell
SeeIt
Clearly
©2010 Olympus America Inc. All rights reserved. Olympus, VivaView, FluoView,
cell^TIRF, and IX are trademarks or registered trademarks of Olympus Corporation,
Olympus America Inc., and/or their afﬁliates, in the U.S. and/or other countries.
mission of transmitting the excitement—and
value—of basic research to the wider world.
Chisholm was a founding member of PIC
in 1992 when early projects included the first
ASCB T-shirts and a press guide to encourage
journalists to cover the Annual Meeting. T-shirts
are not as important as Twitter these days,
but the press guide, originally called Selected
Biomedical Abstracts, has evolved into PIC’s core
product. It is a “peer-screened” selection of newsworthy stories gleaned from Annual Meeting
abstracts. Each story is written to be accessible to
science journalists and the lay public.
The press book’s latest edition, Cell Biology
2010, is a multiplatform, media-friendly
preview of breaking science news at the ASCB
Annual Meeting. It attracted record coverage
of the science presented at the Philadelphia
meeting in news outlets around the world.
News reports from Philadelphia appeared in
or on Science News, ABC News, New Scientist,
Time, Bloomberg Business Week, UPI, Reuters’
Health Day, Baltimore Sun, Voice of America,
US News & World Report, Nature, AOL Health,
The Scientist, Milwaukee Journal-Sentinel,
Guardian (UK), and Daily Mail (UK), among
others.
A citation presented to Chisholm by
PIC declared, “Careful choices, persistent
application, and extraordinary meeting skills
were the marks of Rex Chisholm’s term as
PIC Chair and of his even longer service as a
committee member. Celldance, CellSlam, and
the expansion of PIC efforts into new media all
came together under Rex’s leadership.”
The new Chair, Atkinson, was recruited
to PIC in 2001 through the persistent armtwisting of then-Chair Kathy Wilson.
Atkinson—who chairs the Biology
Department at the School of Science, Indiana
University–Purdue University, Indianapolis—
has been PIC Vice Chair since 2008. He
told the Committee that he will continue
Chisholm’s drive to find new approaches
to disseminating science that reach beyond
the traditional science news media, which
are caught in an ongoing economic and
technological crisis. “Direct to consumer”
science news is now central to PIC’s strategy,
said Atkinson.
Chisholm is one of six PIC members whose
terms ended on December 31, 2010.
In addition, Kip Sluder of the University
of Massachusetts Medical Center, Worcester,
handed on his job as chief judge for the
Celldance Film and Image Contest to Duane
Compton of Dartmouth Medical School.
Atkinson issued a call to ASCB members
interested in public outreach to join the PIC
Associates, an affiliated working group that will
peer screen abstracts and select the stories to be
featured in Cell Biology 2011. Contact ASCB
Science Writer John Fleischman (jfleischman@
ascb.org) for details.
—John Fleischman
Public Policy Committee: Coping
with Uncertain Science Funding
2010
Public Policy
Committee
Thomas D. Pollard,* Chair
William M. Bement*
David Burgess,* MAC
Liaison
Rex L. Chisholm,* PIC
Liaison
George Q. Daley
Robert D. Goldman*
Lawrence S.B. Goldstein
Brigid L.M. Hogan
H. Robert Horvitz
Daniel P. Kiehart
Douglas Koshland*
Connie M. Lee*
Timothy J. Mitchison
Sean J. Morrison
Janet M. Shaw*
Brian Storrie*
Beverly Wendland, WICB
Liaison
Susan Wente*
The 2010 congressional elections returned
control of the U.S. House of Representatives to
the Republican Party and increased the number
of Republicans serving in the U.S. Senate. In
light of these electoral changes and the potential
impact to federal funding for scientific research,
the ASCB’s Public Policy Committee (PPC)
examined what to do to preserve federal support
for research.
In an effort to increase the number of ASCB
members involved in science policy advocacy,
the Committee decided to focus attention on
one state. The goal: to see if it is possible to
increase the involvement of scientists in that
state. Committee members agreed that if the
“one state” experiment succeeds, it would serve
meeting
as a model for increasing participation in other
states.
The Committee also discussed the recent
decision by the National Institutes of Health
(NIH) to create a new NIH center devoted to
translational science. The center would result
from the dismantling of the National Center
for Research Resources (NCRR). Since
the decision was made only days before
the Committee met, members agreed to
continue to review the decision to determine
the effect it would have on ASCB’s members.
The Committee also had another meeting
with National Science Foundation (NSF)
staff. The PPC remains concerned with a
prohibition on the funding of medically
relevant research at the NSF Division of
Molecular and Cellular Sciences. Committee Incoming PIC Chair Simon Atkinson
(left) presented outgoing PIC Chair Rex
members also expressed their concern about Chisholm with a set of posters promoting
attacks by Republican members of the U.S. PIC’s Celldance film and image contest,
House of Representatives on grants awarded which began under Chisholm’s leadership.
by the NSF.
ASCB staff attending the meeting were
ASCB Executive Director Joan Goldberg,
15
2010 Advisory Board
for The Cell: An
Image Library
Timothy J. Mitchison,*
Chair
Bruce M. Alberts
Georjana Barnes
Margaret Clarke
Robert D. Goldman*
Jennifer LippincottSchwartz*
Harvey F. Lodish*
J. Richard McIntosh
Thoru Pederson
Thomas D. Pollard*
David L. Spector*
Tim Stearns
Jeremy Swan
Jason R. Swedlow*
meeting
2010 Women in Cell
Biology Committee
Sandra K. Masur,* Chair
Alexandra M. Ainsztein*
Susan L. Forsburg
Ursula W. Goodenough*
Triscia W. Hendrickson*
Caroline M. Kane*
Harvey F. Lodish*
Elizabeth Marincola*
Inke Näthke
W. James Nelson
Suzanne R. Pfeffer
Lynne M. Quarmby*
Jennifer Roecklein-Canfield*
W. Sue Shafer*
S. Brookhart Shields
Vivian Siegel*
Anne Spang
JoAnn Trejo*
Angela Wandinger-Ness*
Beverly R. Wendland*
Junying Yuan*
* In attendance at December
meeting
16
Coalition for the Life Sciences Director Lynn
Marquis, and ASCB Director of Public Policy
Kevin Wilson. President-Elect Sandra Schmid
also attended the meeting.
—Kevin M. Wilson
Advisory Board for The Cell: An
Image Library—Launching the Site
After a soft launch on August 9, 2010,
The Cell officially launched at the 50th
ASCB Annual Meeting. Funded by a Grand
Opportunities grant from the National
Institute of General Medical Sciences, the
Library has faced a variety of technical challenges. Most have been overcome, the Cell
Advisory Board agreed at its December meeting in Philadelphia. The Board discussed the
key remaining challenges—engaging the community to submit images, videos, and animations and demonstrating the value of participation. To simplify submission to the Library, the
Board learned that:
n Attachments can now be uploaded with the
images to provide experimental details.
n Licensing requirements can now be selected
from a variety of options when uploading
images.
The group discussed further ways to
encourage cell biologists to submit images,
noting that images are peer-reviewed and,
once published, can be noted on a submitter’s
CV. Meeting participants noted that images
in addition to those used quantitatively would
also be valuable and should be actively sought.
The group discussed establishing agreements
with publishers to expand The Cell’s number
of published, high-quality images. (Such
agreements are in process.)
There was strong agreement about the
value of classic collections being presented
in the Library. The effort to acquire and
annotate these classic images has begun, grant
PI Caroline Kane reported, noting that some
are published on the site already. As more of
these collections enter the Library, a Special
Collections page will be developed to help
guide users and provide more context, the
Board agreed.
Some possible new features for the Library
were discussed. One example is a section for
submitting images with a related question, such
as “What is this structure?” The community
could then help determine the answer. There
was also some discussion about possible
future development of an educational overlay
for current materials to make the Library
more useful, not only for researchers, but for
educators and the public as well.
The Board agreed that it is time to survey site
users; this survey is now in preparation. Users
will be encouraged to provide feedback not only
on what is currently useful, but also on what
would make the Library more useful. Learning
how the Library is currently in use will be
beneficial too. Visit www.ascb.org to participate.
Besides Advisory Board members and
PI Kane, Bob Murphy of Carnegie Mellon
University and ASCB staff were in attendance.
—David Orloff
Women in Cell Biology Committee:
Serving the Community through
Annual Meeting Events
Discussions at the December Women in Cell
Biology (WICB) Committee meeting, held in
Philadelphia, focused on WICB events at the
2010 ASCB Annual Meeting:
n The Workshop “Leveraging Your PhD in
the Real World,” moderated by WICB
Committee members Vivian Siegel and
Junying Yuan, with a panel discussion that
included Yi Kong (GlaxoSmithKline),
Jeremy Paul (Skirball Institute), Beth
Schachter (consultant for scientist-to-scientist
communications), Eric Vieira (Mt. Sinai
School of Medicine), and Joanna Watson
(National Cancer Institute)
n The Career Discussion and Mentoring
Roundtables, which attracted over 700
participants and addressed multiple career
choices and issues at a variety of themed tables
n The Mentoring Theater, which blended
humor and serious discussion to spotlight
being overwhelmed and was led by Lynne
Quarmby and panel moderators John
Aitchison (Institute for Systems Biology),
Beverly Wendland (Johns Hopkins), and
Zena Werb (University of California, San
Francisco)
n The WICB Junior Award, presented
to Magdalena Bezanilla (University of
Massachusetts), and Senior Award, presented
to Werb
n The WICB Network Reception, which
afforded members the opportunity to get
more involved in WICB activities and
find out about WICB programs. For more
information or to join the Network, go to
http://ascb.org/index.php?option=com_conte
nt&view=article&id=290&Itemid=152.
The Committee noted the number of
candidates for childcare awards for the 2010
ASCB Annual Meeting and went on to discuss
instituting periodic Committee conference calls,
expanding the list of previous ASCB Annual
Meeting Symposia and Minisymposia speakers
for use in WICB’s Speaker Referral Service, and
revamping WICB’s Facebook page. n
—Cheryl Lehr
Tom Pollard presented WICB’s Junior
Award to Magdalena Bezanilla.
Help Your Society, Grow Your Career
n
n
n
Love the ASCB and want to increase your involvement?
Want an exciting career position?
Have excellent communications skills?
ISO ASCB Senior Director, Communications & Marketing
The ASCB is in search of (ISO) a skilled communicator to
lead staff and work closely with members to plan, coordinate,
and implement data-gathering, branding, and an integrated
communications/marketing plan. Bring your superior skills
to meeting, publication, membership, and new product
communications and development. Website redesign, social
media a plus for hands-on position.
Successful Candidate Will Have Many of These
Qualifications
n Significant scientific background
n Communications, marketing, and branding experience
n Demonstrated ability to lead and mentor a diverse team
and work collegially with staff, volunteers, others
n Excellent communications skills, written and oral
n Critical, analytical thinking, creativity, and flexibility
n A keen eye for good graphic design
n Experience overseeing website development/redesign
Application Submission
Explain why you’re the perfect person for this job in ASCB’s
Bethesda, MD, office; and submit letter with your résumé to
[email protected] by March 7, 2011. EOE.
Valerie Weaver presented WICB’s
Senior Award to Zena Werb (left).
Wanted: ASCB Cell Image Evaluator and
Annotator
Description
The ASCB is seeking PhD or postdoc cell biology or microscopy
consultants, 25% to full-time, starting as soon as possible, until at
least August 31, 2011. Consultants will select exemplary images
and videos from submissions/publications, provide metadata
for short tags or descriptions, select terms from ontologies, and
provide annotations including technical details crucial for image
interpretations. There is no need to relocate.
Requirements
Annotators must be familiar with various imaging techniques
(e.g., LM, transmitted light, epifluorescence, polarization, EM
transmitted, back-scattered SEM, EDAX) and image analysis and
processing (e.g., background subtraction, low-pass noise filter,
3D-deconvolution). Candidates must have expertise in different
areas of cell biology and in evaluating image and video quality.
Access to the Internet and email is required. Flexibility is a must.
Funding
The consultant will work on The Cell: An Image Library
(www.cellimagelibrary.org), the ASCB’s NIGMS-funded, ARRAsupported project. Compensation commensurate with experience.
Application Submission
For complete information and details on submitting an
application, visit www.cellimagelibrary.org/pages/employment.
Application Deadline: February 28, 2011. ASCB is an Equal
Opportunity Employer.
17
Imaging: A Laboratory Manual
Edited by and Series Editor Rafael Yuste
This is the cornerstone of a new laboratory manual
series on imaging techniques, which have become
tremendously valuable in nearly every field of biological
research. Designed as a general reference, this volume
describes the theory and practice of a wide array of
imaging methods.
2011, 952 pp., illus., appendices, index
Hardcover $240
ISBN 978-0-879699-35-2
Paperback $165
ISBN 978-0-879699-36-9
Imaging in Developmental Biology:
A Laboratory Manual
Edited by James Sharpe and Rachel Wong;
Series Editor, Rafael Yuste
This is the second manual in a new series on imaging. It
presents an essential set of visualization methods for
evaluating the dynamic form and function of molecules,
cells, tissues and whole embryos throughout the entire developmental
process in a variety of standard model organisms.
2011, 883 pp., illus., index
Hardcover $240
ISBN 978-0-879699-39-0
Paperback $165
ISBN 978-0-879699-40-6
RNA: A Laboratory Manual
By Donald C. Rio, Manuel Ares, Jr.,
Gregory J. Hannon, and Timothy W. Nilsen
Initiating RNA research can be intimidating but this new
manual provides a broad range of up-to-date techniques
presented in a functional framework, so that any investigator can confidently handle RNA and carry out meaningful experiments, from the most basic to the highly sophisticated.
2011, 586 pp., illus., appendices, index
Hardcover $240
ISBN 978-0-879698-90-4
Paperback $165
ISBN 978-0-879698-91-1
Means to an End: Apoptosis and
Other Cell Death Mechanisms
RNA Worlds: From Life’s Origins to
Diversity in Gene Regulation
Edited by John F. Atkins, Raymond F. Gesteland,
and Thomas R. Cech
This volume reviews our understanding of two RNA
worlds: the primordial RNA world before DNA, in
which RNA was both information store and biocatalyst;
and the contemporary RNA world, in which mRNA, tRNA, rRNA,
siRNA, miRNA, and a host of other RNAs operate.
Hardcover $158
ISBN 978-0-879699-46-8
Auxin Signaling:
From Synthesis to Systems Biology
(A Cold Spring Harbor Perspectives in Biology Collection)
Edited by Mark Estelle, Dolf Weijers,
and Ottoline Leyser
Auxin plays a key role in nearly all aspects of plant
development and physiology. This book provides an
overview of auxin biology, covering auxin biosynthesis and transport,
cellular responses to auxin, and mechanisms of auxin-dependent processes.
Hardcover $135
ISBN 978-0-879698-98-0
Neuronal Guidance:
The Biology of Brain Wiring
Edited by Marc Tessier-Lavigne and Alex L. Kolodkin
A developing neuron responds to cues from its surroundings that influence the connections it makes with its
targets. This book reviews the tremendous progress that
has been made in recent years by studying these cues, the cell-surface
receptors that bind to them, and the resulting intracellular signals and
morphological effects.
Paperback $135
ISBN 978-0-879698-97-3
The Nucleus
By Douglas R. Green
Edited by Tom Misteli and David L. Spector
This short book provides a clear and comprehensive view
Contributors discuss the relationship between nuclear
of apoptosis and other cell death mechanisms. It will
structure and function, the various nuclear bodies that
appeal to everyone from undergraduates encountering
have been identified, the organization of the nuclear lamthe topic for the first time to researchers actively working
ina and nuclear pore complex, the higher-order organiin the field.
zation of chromatin within the nucleus, and the dynamics
of DNA replication, transcription, DNA repair, and RNA transport.
2011, 220 pp., illus., additional reading, index
Hardcover $79
ISBN 978-0-879698-87-4 2011, 517 pp., illus., index
Paperback $45
ISBN 978-0-879698-88-1 Hardcover $135
ISBN 978-0-879698-94-2
The Honest Look
Sydney Brenner: A Biography
By Errol C. Friedberg
By Jennifer L. Rohn
Based on Sydney Brenner’s personal recollections, with
In Jenny Rohn’s second novel, expatriate Claire Cyrus
contributions and correspondence from his close friends
joins a biotech company in the Netherlands, and an acand colleagues, this book tells the lively story, not only
cidental discovery in the lab threatens to bring down caof Brenner himself, but of what came to be known as the
reers, a company, and a widely accepted scientific theory.
“golden age” of biology.
This is a story of how people with various stakes in a common endeavor react when its integrity is called into question, and how these 2010, 334 pp., illus., index
reactions can be shaped—and warped—by denial, greed, hatred, and love. Hardcover $39
ISBN 978-0-879699-47-5
2011, 343 pp.
Paperback $13.99
ISBN 978-1-936113-11-8
Fawcett Memorial Awards Make a Difference
The ASCB specially thanks Mrs. Fawcett and her daughter Dona Fawcett Boggs Aitken for their generous contribution in
2010 to ASCB travel awards in memory of ASCB’s first president, Don Fawcett. Their generosity enabled five undergraduate
students, 15 postdocs, and 35 predoctoral students to attend the 2010 ASCB Annual Meeting. Excerpted below are comments
from some of those grateful attendees to the Fawcett family:
“Thank you for giving me the financial means to
travel to the meeting. It was encouraging to hear
how hard work led to success and how advice
and collaboration can lead to great discovery. I
am now more sure than ever that I want to go
on to graduate school and be a scientist. I am
grateful for your support and that you value the
future of research as much as I do.”
—Helena Lucente, undergraduate student, Central Michigan
University
“I am a proud recipient of a 2010 Fawcett travel
award. I met a lot of leaders in the biology
community and received positive feedback on
my poster. I greatly appreciate your kindness in
establishing a travel fund for the ASCB.”
—Michael Gotesman, PhD candidate, CUNY
Graduate Center
“Thank you so much for the generous gift.
I’m an international student, and the meeting
connected me with students and senior
researchers from different races, religions, and
continents.”
—Ling-shiang Chuang, PhD candidate, Rutgers
University
“Thank you for giving me an opportunity to
attend the meeting. I read an article about Don
Fawcett’s life and his science after I came back
from Philadelphia. It made my heart pound with
respect and honor. Receiving this travel award
boosted my confidence that I can become an
outstanding biologist in the future.”
—HyangMi Amy Moon, PhD candidate, University of California,
San Francisco
“The ASCB meeting was a magnificent
experience. I had the chance to broaden my
scientific and academic horizons, and to meet
influential people in science who have changed
our perceptions and challenged dogmas and
doctrines by relentless motivation and the quest
for knowledge.”
—Meital Oren, PhD student, Technion, Israel
Fawcett travel awardees gathered at the 50th anniversary cake.
It can be said that the American Society for Cell Biology grew out of a rejected EM slide. In 1951,
a high-impact journal turned down Keith Porter and Don Fawcett’s EM-based paper describing
the classic 9+2 microtubule core of the axoneme in cilia. That rejection led to a new journal
and a new society for cell biologists. Fawcett, who was elected by mail ballot as the first ASCB
president in 1961, was also the first to describe the 9+2 microtubule pattern in mammalian sperm
flagella. He was also a pioneer in the cell biology of reproductive tissues. With William Bloom,
Fawcett co-wrote the histology textbook of its day. He mentored dozens of future investigators
and department chairs in his lab at Harvard Medical School. When Fawcett “retired” in 1980, he
set up an international laboratory in Nairobi, Kenya, to study parasitic diseases of cattle. When
he came back from Africa in 1985, he retired again, this time to Bozeman, MT. He died there at
age 92 in 2009. Fawcett was remembered at the 50th Annual Meeting of the ASCB last December
in Philadelphia as a founder and as the namesake for the Society’s Fawcett Travel Awards. A 2000
ASCB profile of Fawcett is online at www.ascb.org/files/profiles/don_fawcett.pdf. n
Don Fawcett
—John Fleischman
19
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First im l Research
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3.368
Stem Cell Research
New Innovations
for Stem Cell Research
Graphical Abstracts –
summarize the contents of the article
in a concise pictorial form
www.elsevier.com/graphicalabstracts
Research Highlights –
bullet points that convey the
core findings of the article
www.elsevier.com/researchhighlights
welcomes papers that
cover all aspects of
stem cells including:
● embryonic stem cells
● tissue-specific cells
● cancer stem cells
● developmental studies
● stem cell genomes
● translational research
Submit your paper at:
http://ees.elsevier.com/scr
SciVerse ScienceDirect top 10 downloaded articles*
Teratoma formation by human embryonic stem cells: Evaluation
of essential parameters for future safety studies. H. Hentze et al
Volume 2, Issue 3, pp 198-210. (2009)
Endothelial cells mediate the regeneration of hematopoietic
stem cells. W.H. Fleming et al
Volume 4, Issue 1, pp 17-24. (2010)
Long term expansion of undifferentiated human iPS and ES cells
in suspension culture using a defined medium. U. Martin et al
Volume 5, Issue 1, pp 51-64. (2010)
Long-term microcarrier suspension cultures of human
embryonic stem cells. S.K.W. Oh et al
Volume 2, Issue 3 pp 219-230. (2009)
Derivation of insulin-producing cells from human embryonic
stem cells. M.S.German et al
Volume 3, Issue 2-3, pp 73-87. (2009)
Human bone marrow-derived mesenchymal stem cells secrete
brain-derived neurotrophic factor which promotes neuronal
survival in vitro. A. Wilkins et al
Volume 3, Issue 1, pp 63-70. (2009)
An adult tissue-specific stem cell in its niche: A gene profiling
analysis of in vivo quiescent and activated muscle satellite
cells. D. Montarras et al
Volume 4, Issue 2, pp 77-91. (2010)
Prediction of drug-induced cardiotoxicity using human embryonic
stem cell-derived cardiomyocytes. C.L. Mummery et al
Volume 4, Issue 2, pp 107-116. (2010)
Exosome secreted by MSC reduces myocardial ischemia/
reperfusion injury. D.P.V. de Kleijn, S.K. Lim et al
Volume 4, Issue 3, pp 214-222. (2010)
Exosome secreted by MSC reduces myocardial ischemia/
reperfusion injury. P.J. Hornsby et al
Volume 4, Issue 3, pp 180-188. (2010)
*SciVerse ScienceDirect January - November 2010
www.elsevier.com/locate/scr
ANNUAL MEETING Highlights
Education Committee Events
Education Workshop
As participants entered the room for the
workshop on “Process Oriented Guided
Inquiry Learning (POGIL): A StudentCentered Approach to Instruction,” they were
sorted into groups of four at either end of a
series of long tables. One person was handed
a folder of materials and told that s/he was the
“Manager;” the other members were designated
as “Recorder,” “Presenter,” and “Reflector.” Rick
Moog and Vicki Minderhout, the workshop
leaders and “Facilitators,” set ground rules: 1)
make sure each participant understands his/
her role, and 2) when a facilitator raises a hand,
whoever sees it stops talking and raises a hand
until the room is quiet (an amazingly rapid
process). Participants were thus embarked on
immersion in the POGIL process.
A POGIL classroom requires collaborative
work in small groups on activities specifically
designed for this use, with the instructor
serving primarily as a facilitator of the students’
learning. Additional common features of a
POGIL classroom include no prior experience
with the topic (through lecture or reading)
before the class activity and assigned roles (as
above). Roles are switched regularly during the
semester so each student has practice in each
role. Students work collaboratively on critical
thinking questions that are designed to be
completed during about 40 minutes of class
time. Within these guidelines, every POGIL
implementation is unique to the particular
instructor and the subject matter at hand. The
workshop itself followed these guidelines.
As a warm-up exercise, each group was asked
to identify the two or three most important
student outcomes from a recent course that
members had taught. Participants then heard
one example from the Reporter in each group.
The pace was brisk. Reporters were given just
10 seconds. The rest of the formal workshop
followed this basic pattern.
reported on questions designed to establish the
facts of the case and then to understand their
implications both quantitatively and logically.
The Recorder kept track of the discussion, and
the Reflector’s task was to be
aware of the process by which
the group reached its answers.
By limiting the time available
for discussion, the facilitators
kept the conversation on track.
At the end the Reflector was
asked to report on the strengths
and weaknesses of the group
interaction.
Participants realized that
such an activity could teach
not only content, but also
group dynamics. This led to
a deconstruction of the terms
in the POGIL acronym:
“Process Oriented” refers to
the teamwork, the exploration
of the problem, the invention
of guiding concepts, and their
Rick Moog and Vicki Minderhout (top) presented
application to new situations;
Process Oriented Guided Inquiry Learning to
“Guided Inquiry” refers to the
attendees (bottom) at the Education Workshop.
learning cycle modeled in each
activity.
Participants then undertook a second group
activity interpreting and applying information
from a schematic diagram of a watershed.
Here the questions stepped the groups through
interpreting the diagram accurately, noting the
use of special terms, comparing a surface view
to a cross-sectional view, and then developing
a definition for the term “watershed divide.”
This approach to terminology avoids the
shallow understanding gained by memorizing
definitions. As group members worked, they
were asked to identify which part of the learning
cycle was addressed by each question. Thus
participants continued to experience POGIL
themselves.
Learning about Content and Interaction
Participants performed two POGIL activities.
The first, on credit default swaps, led
participants through successively more complex
arrangements to protect an asset by insuring
it, taking into account the probability of
loss. At each stage the group discussed and
Assessing Results
In a wide-ranging discussion at the end, the
facilitators presented assessment results in
which two general chemistry classes were
compared, one using conventional lecture and
the other using POGIL supplemented by peerled discussion groups. The same amount of
21
contact time led to much better performance
on all but the first of the tests on the part
of the POGIL-instructed group. In another
assessment, students in Organic Chemistry 2
were given an unannounced quiz
on the first day of class to see how
much of Organic Chemistry 1
had been retained. Those students
who had POGIL instruction
had much better retention than
students who had conventional
instruction.
POGIL is a nationally
organized network of U.S.
participating faculty. Readers
Amy Gladfelter (third from left), representing
can register at www.pogil.
Dartmouth College, talked to students at the
org to be included in regular
ASCB’s first Graduate School Fair.
communications. Inexpensive
regional U.S. meetings are
conducted in the summer to assist
participants in revising courses.
Plans are under discussion to
collect POGIL activities on a
curated website, since planning
and testing activities are the most
difficult aspect of the process.
Group shot of all the undergraduate poster
—Mary Lee Ledbetter
presenters
Undergraduate Program,
Undergraduate Poster
Session, and Graduate
Fair
Demonstrating the ASCB
commitment to undergraduate
education, Amy Gladfelter,
Dartmouth College, gave an
Kristen Karasiewicz discussed her poster.
engaging and motivating talk to
more than 200 undergraduate
students, faculty, and other ASCB
attendees at the Undergraduate
Program. Gladfelter’s talk focused
on three different areas. The first
portion described her path from
childhood to adult scientist and
emphasized the roles mentors
and chance meetings with other
scientists played in her career
Louis Stark (third from left) with participants
decisions. The second portion
at the K–12 Science Education Workshop
detailed two ongoing research
projects in Gladfelter’s lab. Using
movies, graphs, and confocal
microscopic images, Gladfelter explained
her interest in nuclear anarchy and cortical
22
organization in Ashbya gossypii (a filamentous
fungus) and Saccharomyces cerevisiae (budding
yeast). Finally, she vividly described her daily
activities as a scientist and faculty member,
relating her duties to those activities the students
also do every day.
After her presentation Gladfelter attended the
undergraduate poster session, engaging many of
the students in the details of their work. Over
80 students presented posters at the session.
Members of the ASCB Education Committee
and many other ASCB attendees also interacted
with the undergraduate students, making for a
lively and energetic poster session.
In addition to the seminar and the poster
session, a new feature of the 2010 ASCB
Annual Meeting was a Graduate School Fair.
Representatives from 30 graduate schools were
available to talk to the undergraduate students.
The tables were crowded with interested
undergraduates for the entire hour of the
graduate fair.
—Elisa Konieczko for the Education Committee
K–12 Science Education Workshop
Imaginative educational activities make
science fun and memorable for high school
and undergraduate students. Louisa Stark,
University of Utah, presented various learning
modules from the Genetic Science Learning
Center’s website (http://learn.genetics.utah.
edu). Attendees at the workshop participated
in hands-on activities from the Amazing Cells
module on the Center’s website. The activities
included building a cell membrane and
estimating relative sizes of biological structures
from atoms to cells. These activities provoked
interesting discussions among the participants as
they were asked to rank each structure.
Workshop participants (who included
high school teachers and educators of college
undergraduates) also acted out signal pathways,
prompted by instructions from the website. The
program offered an excellent opportunity to
learn from a thorough and imaginative website.
The event was supported by Aquatic Habitats,
Inc.
—William Wallace for the Education Committee
Education Minisymposium
Speakers at the “Cell Biology Education:
Where’s the Math?” Minisymposium
highlighted the need for training math-savvy cell
biology students who can do the quantitative
analysis needed for the next wave of substantive
discoveries. Faculty scientist educators John
Jungck (Beloit College) and Pat Marsteller
(Emory University) offered concrete examples
about how to engage faculty in modifying
course content to include more quantitative
analyses. Next, Omar Quintero (Penn State
College of Medicine) illustrated specifically how
wet labs can be modified so that students have
more time to analyze data instead of putting all
their energy into learning laboratory techniques.
Julien Berro, a postdoctoral fellow at Yale
University, encouraged attendees to spend time
with a mathematician to model one’s favorite
cellular process, and to invite a mathematician
into the laboratory to test the model. He also
provided a specific example of how the model
suggests experiments and how the experimental
results lead to model revision—much like the
course of science.
A graduate student, Julia Philip (University
of Notre Dame), described a binding simulation
tool for any polymer binding protein. The tool,
which is useful and accessible for researchers and
educators, provides tangible and understandable
“reasons” that both thermodynamics and
kinetics are needed to describe regulation of
binding parameters. Finally, an undergraduate
student, Samantha Lindemann (University
of Minnesota, Duluth), presented the use
of statistics in a teaching setting to evaluate
Mendelian genetics and to demystify the
statistical approach; she was developing learning
modules that allowed her undergraduate
research to couple the science and the math.
—Caroline Kane and Sue Wick for the Education
Committee
Postdoc Workshop
Young scientists are still woefully ignorant of
the diversity of career options available to them,
making the transition to a nonacademic career
extremely difficult. For the fourth consecutive year,
the ASCB Subcommittee on Postdoctoral Training
presented a workshop to provide information
about various career options: “Getting Out of the
Box: Transitioning to a Career outside of Academic
Research.” Over 300 attendees asked questions
of the five-member panel for two hours. This was
followed by one-on-one networking for those
remaining after the session.
The workshop panelists, all of whom began
their careers as research scientists, represented
a wide array of career choices. They included
Claudia Low, CBCE; Alan Cheshire, The
Boston Consulting Group; Graham Long, TGR
Biosciences; Ellie Cantor, CJ Resources, and
Steven Snyder, The Franklin Institute. Speakers
first discussed how they made the transition to a
career outside of academic research and various
life events that led to their career decisions.
Many questions from the audience centered
on how to transition to nonacademic careers,
including networking and how to get “a foot in
the door.”
Highlights of the panel’s recommendations
included:
n Be proactive! Talk to people
who represent the careers
you’re interested in; this is how
networking starts. Don’t be afraid
to contact people/a company and
ask for information about their
jobs (even if there is no posting);
this might even lead to a job offer.
n Be flexible, especially in these
times of economic crisis. Cantor
noted that she started teaching at
a local school when her company
started slowing down and found
she loved this new facet of her
career.
n Remember, this is your career.
Don’t let concerns over what
your colleagues will think of
your goals affect your actions.
Scott Gilbert (top) engaged students (bottom)
Snyder commented that his PI
at the High School Program.
was derisive about his decision
to pursue outreach teaching
programs, but he has never regretted his
choice.
n Don’t get discouraged. Long commented
that scientists are willing to put a lot of
energy into optimizing an experiment, but
often don’t realize that the same focus and
determination are required to optimize a
career.
—Kyle Draheim for the Education Committee
High School Program
Approximately 300 Philadelphia high school
students attended a fascinating talk by Scott
Gilbert of Swarthmore College. Gilbert
spoke on “How the Turtle Got Its Shell; How
the Bat Got Its Wings: Evolution through
Developmental Changes.” He presented
contemporary ideas about the fusion of
evolutionary biology and developmental
23
biology using the turtle’s unusual carapace
structure as an example. The students were
particularly fascinated by the evidence that
the turtle carapace starts as the rib cage in the
fetus but develops into an external shell due to
the action of specific growth factors. Gilbert
told the students about a human disease
(fibrodysplasia ossificans progressiva) that
mimics this process.
After a lively Q&A session, students visited
the Exhibit Hall. They especially enjoyed
exploring the Cell Motion BioBus, a school bus
that has been equipped as a microscopy lab.
—William Wallace for the Education Committee
Bruce Alberts Award
John Jungck of Beloit College and Sam
Donovan of the University of Pittsburgh
accepted the Bruce Alberts Award for Excellence
in Science Education on behalf of
all members of the BioQUEST
Curriculum Consortium (www.
bioquest.org). BioQUEST
actively supports undergraduate
biology education through
collaborative development of
open curricula in which students
pose problems, solve problems,
and engage in peer review.
BioQUEST has a 20-plusyear history of educational
Caroline Kane (left) presented the Bruce Alberts
innovation emphasizing effective
Award to Sam Donovan (center) and John Jungck
uses of inquiry, technology,
(right) on behalf of the BioQUEST Curriculum
Consortium.
and participatory models of
curriculum development.
BioQUEST offers numerous
resources online as well as workshops for
educators at all levels. Its activities are having an
impact internationally.
In their award acceptance presentation,
Jungck and Donovan highlighted how students
with heterogeneous talents work together, and
how faculty also work together to “change
learning, not teaching.” They highlighted
quantitative problem solving and data analysis.
They emphasized that students working with
real data develop new ways of visualizing
and interpreting the information. Moreover,
curricula that include evolution data and
quantitation are leading to the development
of laboratories that are more open-ended and
investigative. This is similar to the way science is
conducted by those in a research setting.
—Caroline Kane for the Education Committee
24
Career Program
One of the most popular sessions sponsored by
the Education Committee was a career program
for graduate students and postdocs, entitled
“One Job Title, Many Tracks: How to Prepare
for the Academic Career That Best Suits Your
Interests.” The panelists, Anthony K. Koleske,
Yale University School of Medicine, Kathy T.
Schmeidler, Irvine Valley College, and Michael
J. Wolyniak, Hampden-Sydney College—all
Education Committee members—presented
some of the differences in working at a research
university, liberal arts college, or community
college. They discussed teaching loads, research
and publication expectations, and quality of
life. There was a lively Q&A session at the
end, during which one attendee announced
a teaching position opening at his school. A
videotape is available (see p. 34).
—Thea Clarke
Education Initiative Forums
In the first Education Initiative Forum Elisa
Stone of the University of California, Berkeley,
CalTeach Program and Kristy Wilson from the
Fellowship in Research Science Teaching (FIRST)
program at Emory University discussed programs
that combine research and training in teaching.
The CalTeach Program prepares
undergraduate students to become science
teachers. Besides taking science courses
alongside education courses, students can
do summer research with nearby biology
scientists. Using the Web-based Inquiry Science
Environment (WISE; http://wise.berkeley.edu)
as a guide, Stone administers pre- and postquestions to students. The answers enable her
to develop rubrics to capture what students
learn and to inform the design of the program.
What do they learn? Students had an increased
appreciation of the need for collaboration and
communication in science and the relationship
of science to society. Stone is continuing to
modify the summer research course to support
student understanding of scientific processes.
Wilson discussed the FIRST program, which
trains researchers to teach. The FIRST program
links postdoctoral fellows at Emory with faculty
and teaching experiences at partner minorityserving institutions (MSIs): Clark-Atlanta
University, Morehouse College, and Spellman
College. How do three years of training in
teaching affect the careers of these postdoctoral
fellows? Wilson provided detailed information
Frontiers in Cell Migration &
Mechanotransduction
May 24-26, 2011
Natcher Conference Center
National Institutes of Health
Bethesda, MD
Conference Organizers
Rick Horwitz (University of Virginia)
Tom Parsons (University of Virginia)
Martin Schwartz (University of Virginia)
Keynote Lectures
Graham Dunn (King’s College London, England)
Gaudenz Danuser (Harvard Medical School)
Peter Friedl (Radboud University, Netherlands)
Scientific Sessions and Speakers
Visualizing Migration
Mary Dickinson (Baylor College of Medicine)
Ernst Stelzer (EMBL – Heidelberg, Germany)
John Condeelis (Albert Einstein College of Medicine)
Biology of Mechanotransduction
Valerie Weaver (University of California - San Francisco)
Patricia Keely (University of Wisconsin - Madison)
Clare Waterman (National Institutes of Health/NHLBI)
Adhesion and Cytoskeleton
Ohad Medalia (Ben Gurion University, Israel)
Dorit Hanein (Sanford-Burnham Institute)
Anna Huttenlocher (University of Wisconsin - Madison)
Mechanisms of Mechanotransduction
Michael Sheetz (Columbia University)
Chris Chen (University of Pennsylvania)
Martin Schwartz (University of Virginia)
Development
Douglas DeSimone (University of Virginia)
Denise Montell (Johns Hopkins Medical School)
Jean Schwarzbauer (Princeton University)
Computational Modeling
Alex Mogilner (University of California - Davis)
Doug Lauffenburger (Massachusetts Institute of Technology)
Shayn Peirce (University of Virginia)
Systems Approaches
Benjamin Geiger (Weizmann Institute, Rehovot, Israel)
Martin Humphries (University of Manchester, England)
Joan Brugge (Harvard Medical School)
Integrating Migration Processes
James Norman (Beatson Institute, Glasgow, Scotland)
Gregg Gundersen (Columbia University)
Chris Marshall (ICR, London, England)
Polarity
Orion Weiner (University of California – San Francisco)
Tobias Meyer (Stanford University)
Jason Haugh (North Carolina State University)
Poster Sessions
Photomanipulation and Biosensors
Klaus Hahn (University of North Carolina - Chapel Hill)
Barbara Imperiali (Massachusetts Institute of Technology)
Jin Zhang (Johns Hopkins Medical School)
Sponsored by
For additional information
and registration, visit
www.cellmigration2011.org
Cell Migration Consortium (www.cellmigration.org) and National Institute of General Medical Sciences (www.nigms.nih.gov)
Left to right: Elisa Stone and Kristy
Wilson at the Monday Education
Initiative Forum
Left to right: Gordon Rule, Diana Bajzek,
Caroline Kane, and Karen Resendes at
the Tuesday Education Initiative Forum
on the success of the FIRST Fellows in
comparison to other Emory postdoctoral fellows
in T32 programs. Looking across number of
publications per year and grant funding (R and
K awards), the postdoctoral fellows in FIRST
did as well or better than colleagues in the
traditional T32 programs. Over 60% of FIRST
graduates have become faculty at research
institutions, liberal arts colleges, and MSIs.
In the second Education Initiative Forum,
Karen Resendes of Westminster College and
Gordon Rule of Carnegie Mellon University
made presentations that addressed issues
related to content delivery, retention, and
educational outcomes. By comparing pre- and
post-exam answers to questions that covered
material presented to students at San Diego
State University, a large state university, and
Westminster College, a small, liberal arts college,
Resendes found that content retention was
not significantly affected by mode of content
delivery. The types of delivery included a small
lecture/lab setting, an online course, and a
blended (lecture and online) approach.
Rule demonstrated the use of the Open
Learning Initiative at Carnegie Mellon
University. This approach, which is available
for use by the broader educational community,
provides instructors with an opportunity to
use simulations, animations, and embedded
assessment tools in their classes. Both talks
highlighted the variety of interactive, computerbased, and creative approaches that are available
for enhancing instructional activities and
improving educational outcomes.
—Raquell Holmes and Jerry Reagan for the
Education Committee
International Affairs Committee Event
IAC Member Jitu Mayor and Councilor Sue Wick
participated in IAC’s Roundtable discussion.
IAC Roundtable
The International Affairs Committee (IAC)
Roundtable was held again this year in
Philadelphia. This Saturday event is always
popular, and the energy and enthusiasm of
26
the participants were once again contagious.
This year about 200 people attended: graduate
students and postdocs from the U.S. and from
nations all over the world, including Australia,
Ghana, Brazil, India, China, and Europe. After
an introduction and welcome by IAC Chair Jim
Spudich, the participants had an opportunity to
share with each other what cell biology education
and scientific training is like in their respective
countries of origin. ASCB Council members
and IAC members and associates served as
table moderators. The informal atmosphere of
the Roundtable continues to foster thoughtful
discussions about how ASCB can best support
the next generation of cell biologists, an
increasingly international and global community.
—Deborah Lycan for the International Affairs
Committee
ASCB Annual Meeting
ASCB President-Elect Sandra Schmid with E.B. Wilson
award winners (left to right): Stuart Kornfeld, Randy
Schekman, and James Rothman
Maria Murray
Oluwole Ariyo, Jungwoo Lee
Omar Quintero, Jennifer Ross
There was time for both family and science at the
meeting.
Attendees in the Exhibit Hall
Shinya Inouye, Tim Mitchison
Margaret Reed Lewis’s microscope (circa 1913), on
loan from Leonard Hayflick, was on display.
Fiona Watt, Eric Wieschaus, Elaine Fuchs
Linda Hicke, Peter Walter
For more photos, visit www.ascb.org, click on “Photos from the 50th Annual Meeting”.
27
Substantial financial
assistance is available
for many of our courses!
2011 Courses
Analytical & Quantitative Light
Microscopy
May 4 - May 13
Methods in Computational
Neuroscience
July 31 - August 28
Biology of the Inner Ear
August 7 - August 27
Microbial Diversity
June 11 - July 28
Biology of Parasitism: Modern
Approaches
June 17 - August 6
Molecular Biology of Aging
July 24 - August 13
BioMedical Informatics
1st Session: May 29 - June 4
2nd Session: September 18 September 24
Embryology: Concepts & Techniques
in Modern Developmental Biology
June 4 - July 17
Frontiers in Reproduction: Molecular
& Cellular Concepts & Applications
April 30 - June 12
Frontiers in Stem Cells and
Regeneration
October 2 - October 8
Gene Regulatory Networks
for Development
Molecular Mycology: Current
Approaches to Fungal Pathogenesis
Strategies and Techniques for
Analyzing Microbial Population
Structures
Summer Program in Neuroscience,
Ethics, & Survival (SPINES)
June 18 - July 16
Workshop on Molecular Evolution
July 24 - August 3
Zebrafish Development & Genetics
Neural Systems & Behavior
June 4 - July 31
Neurobiology
June 4 - July 31
Neuroinformatics
Optical Microscopy & Imaging
in the Biomedical Sciences
Physiology: Cell & Computational
Biology
June 11 - July 31
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Minorities Affairs Committee (MAC) Events
Mentoring Program Keynote
Isiah Warner’s presentation to minority students,
researchers, and others was enlightening! Warner,
Boyd Professor at Louisiana State University,
shared how he navigated his path to success
in scientific research. His talk highlighted his
humble beginnings as a young boy working in the
fields of Louisiana to his life-changing decision to
attend Southern University. Warner spoke openly
about how past discriminations shaped many of
the key milestones in his career. One bittersweet
milestone he mentioned was being offered a
professorship in the Chemistry Department at
Louisiana State University, which was once a
segregated institution. This opportunity, along
with several others, profoundly influenced
his strong commitment to give back to his
community and society at large.
Warner stated that his mentoring motto is to
increase diversity and mentorship opportunities
for those with similar disadvantaged
backgrounds like his own. Warner ended his talk
by softly announcing that his dream is to show
as many as he can, what they can be! This talk
was videotaped and is available on the ASCB
website (see p. 34).
—Stephanie Crockett, MAC Travel Awardee,
University of California, Davis
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Clockwise, left to right; MAC
Chair Renato Aguilera with MAC
Mentoring Keynote Speaker Isiah
Warner; MAC Poster Presenter
Kevin McKenzie discussed his
poster with a MAC judge; and
MAC Chair Renato Aguilera
and 2010 ASCB President Tim
Mitchison with MAC Poster
Competition Winners.
Strategies and Tactics of
Grantsmanship Seminar
Approximately 150 eager people attended the
grantsmanship seminar led by Beth Schachter
of Stillpoint Coaching & Consulting. She is a
cell biologist and science communicator who
founded her firm to assist researchers with all
aspects of the preparation of manuscripts for
publication and grant proposals for submission.
Schachter focused on how to be successful
in obtaining funding from the U.S. National
Institutes of Health (NIH) and National Science
Foundation (NSF) for research. She emphasized
programs available for postdoctoral fellows and
junior faculty members.
She shared eight rules for grant seekers:
n Align your proposal with the mission of the
funding agency.
n Consult with the program officer for advice
early on in the process.
n Plan to spend months, not weeks, on your
grant proposal.
Learn and follow all rules dealing with the
proposal’s content and format.
Use clear, simple writing and graphics, and
an uncluttered format.
Make sure the reviewers are not the first
people to critique your proposal.
Craft a proposal that an expert in your field
will want to defend and a program officer
will want to fund.
If at first you don’t succeed— try, try again.
In addition:
Familiarize yourself with your potential
reviewers and be sure to cite their work if
appropriate in your proposal.
Publish a manuscript containing the
preliminary data that underpin your proposal.
Take advantage of the current push at the
NIH and NSF to fund proposals by earlycareer scientists.
Craft your specific aims page carefully to take
your reviewers on a journey that makes them
eager to read the rest of your proposal. Talk
about the significance of your proposed work
and how you have put together the best team
and resources possible to meet the specific aims.
n Deal with writer’s block by breaking the task
into smaller chunks and varying your routine in
terms of the time of day and place for writing.
For more details about these points, please
see the article by Beth Schachter on p. 49. Also,
a videotape is available (see p. 34).
—Latanya Hammonds Odie, MAC Visiting
Professor, Georgia Gwinnett College
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2010 MAC Poster Winners
Undergraduates
First Place: Derrius Quarles, Morehouse College
Second Place: Sabrina Easington, Prairie View A&M University
Third Place: David Guerrero, College of Mount Saint Vincent
Graduate Students
First Place: Daniel Feliciano, Colorado State University
Second Place: Charisa Cottonham, University of Massachusetts Medical School
Third Place: Linette Castillo-Pichardo, University of Puerto Rico-Medical
Sciences Campus
Postdoctoral Fellows
First Place: Montrell Seay, Yale University
Second Place: Daniele Ejzykowicz, California State University, Long Beach
Third Place: Veronica Segarra, University of Miami, Miller School of Medicine
Faculty
First Place: Santiago Di Pietro, Colorado State University
Second Place: Ruben Aguilera, Purdue University
Third Place: Luis Vidali, Worcester Polytechnic Institute
Undergraduate/Graduate Training
Session
“Expectations of the Undergraduate Years to
the Preliminary Examination” was the subtitle
of an information-packed MAC session with
presenters Andrew G. Campbell from Brown
University and Michael J. Leibowitz from
UMDNJ–Robert Wood Johnson Medical
School. This seminar was targeted toward
undergraduate and beginning graduate students.
Presenters shared information about the true
reality of graduate school. Topics such as
graduate school responsibility, payment for
services, the application process, the difference
between an MS and a PhD, choosing a proper
mentor, and how to find success overall were
discussed.
This session was important for MAC
attendees because there was an opportunity
for awardees to ask questions with a minority
perspective. This session was videotaped and is
available on the ASCB website.
—Danjuma Quarless, MAC Travel Awardee,
University of California, San Diego
MAC Poster Competition
A distinguished panel of judges reviewed a
record-breaking number of posters—over 70—
at the MAC 2010 Annual Poster Competition!
Extensive interaction and networking were
enjoyed by MAC Poster Competition presenters,
judges, the MAC, MAC Visiting Professors,
Linkage Fellows, and other attendees. MAC
member and Poster Competition Coordinator
Tama Hasson was pleased with comments she
received about a new rubric she introduced for
MAC’s poster program. Poster winners (left)
were notified of their winning status during
the annual MAC Awards Luncheon. Winners
received a cash reward as well as a certificate and
an ASCB 50th Anniversary t-shirt.
—Deborah McCall
MAC Awards Luncheon
Once again, the MAC hosted its Annual MAC
Awards Luncheon where poster winners were
notified of their winning status, the MAC year
was reviewed, and attendees networked.
A highlight of this year’s luncheon was
the presentation of E.E. Just Medals to past
awardees (below). The E.E. Just Lecture presents
research from some of the most prominent
minority researchers in the U.S. Medals will be
mailed to all past awardees not at the luncheon.
—Deborah McCall
E.E Just Awardees
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
George Langford*
James Gavin III
Baldomero Olivera
Franklyn Prendergast
Eloy Rodriguez
Winston Anderson
Lydia Villa-Komaroff
David Burgess*
Frank Talamantes*
Richard Goldsby*
Sandra Murray*
Margaret Werner-Washburne*
Stephen L. Mayo
Alexandro Sanchez Alvarado
James Earl King Hildreth
Jerrel Louis Yakel
Tyrone B. Hayes*
*Present at the MAC Awards Luncheon
30
E.E. Just Lecture
This year’s E.E. Just Lecture was presented
by Tyrone Hayes, University of California,
Berkeley. Many commented that Hayes’s talk—
entitled “From Silent Spring to Silent Night:
What Have We Learned?”—was one of the best
E.E. Lectures they had attended.
Hayes’s talk was on his work with
atrazine, which demasculinizes and feminizes
vertebrate animals primarily by inducing
aromatase, which results in a higher estrogen:
androgen ratio. Very passionate about his
work, Hayes shared that he is concerned
about the role that atrazine and other
chemicals play in minority communities that
suffer healthcare disparities.
Hayes also attended the MAC Awards
Luncheon and visited the MAC Welcome
Suite. Students converged on Hayes and he
patiently talked to them. Hayes is known for his
commitment to student development.
Hayes was presented with a plaque and an
E.E. Just medal after his talk. This talk was
videotaped and is available on the ASCB website
(see p. 34).
—Deborah McCall
Educational Resources/MAC
Booth and MAC Welcome Suite
The Educational Resources/MAC
Booth was always busy! Networking,
presentations and information
dissemination were everyday activities
at the “official hangout” for the MAC
community. All MAC travel awardees were
required to be at the booth for at least one
hour during the Annual Meeting. Many
stayed much longer and came back day
after day. As one travel awardee stated,
“I did my one-hour duty, but could not
leave. I met so many great people.”
The MAC Welcome Suite, like the
Educational Resources/MAC Booth,
was quite popular among attendees. In
its fourth year, this gathering, sponsored
by the MAC and held for three days
during the Annual Meeting, has become
a “mainstay” of the MAC. The MAC
Welcome Suite, supported for its
networking and information sharing by
the Burroughs Wellcome Fund, receives
high ratings on MAC’s evaluations.
—Deborah McCall
Top: Past E.E. Just Awardees
(present at MAC Awards Luncheon)
gathered for a photo after receiving
their E.E. Just Medals; bottom:
2010 E.E. Just Awardee Tyrone
Hayes with 2010 ASCB President
Tim Mitchison
Public Information Committee Events
Discovery as an Occupation:
Conversations with Cell Biologists
The setting was instantly familiar—comfortable
armchairs, a circle of guests, two cameras, and a
skilled interviewer. The subject matter, though,
was not your typical late-night television chat
but a personal and often funny discussion of the
“inner game” of research science. Staged at the
ASCB’s 50th Annual Meeting as an experiment
in public outreach, Discovery as an Occupation:
Conversations with Cell Biologists was moderated
by Rex Chisholm, then chair of the ASCB’s Public
Information Committee (PIC). Chisholm sparked
a freewheeling conversation among Nobel laureates
Eric Wieschaus and Martin Chalfie, along with
2011 ASCB President Sandra Schmid.
“I want to get at the questions that many of
us have struggled with throughout our careers,”
Chisholm explained beforehand. “For example,
how do you know if a scientific question is
actually interesting or important? How do you
know when you’ve made a wrong turn in your
experimental strategy?”
The live show was taped before a small
but appreciative audience at the Pennsylvania
Convention Center. That original audience will
be greatly expanded as Conversations moves to
the Internet. The webcast of Discovery as an
Occupation: Conversations with Cell Biologists is
a PIC experiment to bring the personalities and
the day-to-day issues of basic research work to
a target audience of young scientists, students
at all levels, and the general public. Edited into
short, self-contained segments, Conversations
will be posted on the ASCB website, YouTube,
iBioMagazine, and similar outlets. Check www.
ascb.org (see p. 34) for the Web premiere of
Discovery as an Occupation: Conversations with
Cell Biologists.
—John Fleischman
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Celldance Winners Grab Bright
Lights in Philadelphia
Hailed by The New Scientist magazine as
“biology’s answer to the Oscars,” Celldance,
the ASCB’s annual video and image contest,
unveiled this year’s winning entries to an excited
crowd gathered in the Exhibit
Hall. The 2010 Celldance
“Winners’ Reel” of images and
videos has now been posted at
www.ascb.org/pressbook/2010/
embargo/pressbook.html.
Science news websites around
the world also picked up the
Celldance 2010 winners.
Something incredibly
small—a fruit fly embryo—
performing something epic—
sealing its new epidermis shut—
was the star of U. Serdar Tulu’s
winning video entry, Cellular
Recognition. Tulu, of Duke
University, took home $500 and
First Prize in the film portion
of Celldance 2010. Li He of
Top: “Discovery as an Occupation” featured
then PIC Chair Rex Chisholm (left), Nobel
Johns Hopkins University won
laureates Eric Wieschaus (second from
First Prize and $500 in the
left) and Martin Chalfie (right), and then
Celldance stills competition with
President-Elect Sandra Schmid. Bottom: 2010
“Actomyosin and Focal Adhesion
Celldance winners: left to right, back row:
Kira Henderson, Rosalind Silverman, Torsten
in Fly Egg Chamber,” a confocal
Woellert; front row: Serdar Tulu, Jason Stumpff,
micrograph of the follicle cells of
Karl Lechtreck, Leonard Bosgraaf, Li He, and
a fruit fly egg chamber stained
Judge Kip Sluder.
in three colors that resembles a
stained glass window.
Winner of the special video prize for Public
Outreach was Leonard Bosgraaf of Molecular
Shots, Inc. His film, Firing Neurons, is a
computer animation that takes the viewer inside
neurons firing action potentials.
In all, Celldance 2010 recognized 10 ASCB
members for their visually engaging and
scientifically important videos and images, most
created for experiments that explore the cellular
mechanisms underlying human health and disease.
In the video category, Second Place was ruled
a tie by the judges. Sharing the honors and
taking home $150 each were Karl Lechtreck,
University of Massachusetts Medical School,
for Motion of Epidymal Cilia, and Rosalind
Silverman, University of Toronto, for Fifty
Stars—Fifty Years, which showed cycles of
division of Drosophila embryos injected with
green fluorescent protein.
In the still image category, Graham Johnson,
32
Scripps Research Institute, won Second Place
and $300 for “Promiscuous Membrane Drug
Transporters,” which illustrates multi-drug
resistance transporters. The judges did not award
a third place in images but named two Honorable
Mentions. The Second Place image winner
Johnson was named for “Patronus,” which
illustrates the patronin protein and reminded
Johnson of the Harry Potter character Patronus.
Second Place video winner Silverman took the
other Honorable Mention in images with “An
Extended Actin Net.”
There were four Honorable Mentions in
video: Mary David, Molecular Devices, Inc.,
for The Chase; Kira Henderson, Rensselaer
Polytechnic Institute, for Cellular Wasteland;
Jason Stumpff, University of Washington, for
Interphase Mitochondria Dynamics; and Torsten
Woellert, Syracuse University, for Migration of
Human Oral Keratinocytes.
Kip Sluder, University of Massachusetts
Medical Center, was the awards ceremony emcee
and Chief Judge for Celldance 2010. He was
joined by Duane Compton, Dartmouth Medical
School, who will take over the Celldance
subcommittee in 2011.
Other Celldance 2010 video judges were
Lee Ligon, Rensselaer Polytechnic Institute;
David Burgess, Boston College; Jean Sanger,
State University of New York Upstate Medical
University; and Pat Wadsworth, University
of Massachusetts, Amherst. The Celldance
still images were judged by Caroline Kane,
University of California, Berkeley; Sandra
Murray, University of Pittsburgh School of
Medicine; and Margaret Clarke, Oklahoma
Medical Research Foundation. Qimaging
supported the event.
According to Rex Chisholm, then chair
of the Public Information Committee, cell
biology is an intensely visual science. It grew
into a scientific field after World War II with
breakthroughs in imaging technologies such
as electron microscopy. Fifty years later, cell
biology remains strongly visual as developments
in fluorescent proteins, metallic nano tagging,
and resolution of complex life processes on
the molecular level reveal new patterns of life.
“Most cell biologists are in large part motivated
by the beauty they see in cells every day of their
professional life,” said Chisholm. “In one sense,
working with cells is like working in an art
gallery where the art changes every day.”
—John Fleischman
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Public Policy Committee Events
2010 ASCB Public Service Award
Tom Pollard, recipient of the 2010 ASCB
Public Service Award and long-time public
policy advocate, has one question for his
fellow scientists, “Why is the rank-and-file
membership of the NRA [National Rifle
Association] more concerned about restrictions
on firearms than biological scientists are about
their financial and professional lifeline?”
In his remarks, Pollard retraced the ASCB’s
leadership in science policy advocacy since
April 1988. That was when the ASCB Council
decided to hire a professional staff for a one-
View/download Presentations from
the 2010 ASCB Annual Meeting in
Philadelphia
To view presentations, visit www.ascb.org, click on “Members
Only,” then “Multimedia Content (Video/PPT slides).”
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Keynote Symposium—Looking Back: ASCB’s First Meeting, Gary
Borisy, and Improving Cancer Chemotherapy: How Can a Basic Scientist
Contribute? Timothy J. Mitchison (Video)
Keith R. Porter Lecture—How the Endoplasmic Reticulum Gets into
Shape, Tom Rapoport (Video)
Public Service Award—Thomas D. Pollard (Video)
E.B. Wilson Lecture—Stuart Kornfeld, James K. Rothman, Randy W.
Schekman (Video)
Discovery as an Occupation: Conversations with Cell Biologists, Rex
Chisholm, Eric Wieschaus, Martin Chalfie, Sandra Schmid (Video)
Funding for taping the following presentations was provided by
a Minority Access to Research Careers grant from the National
Institute of General Medical Sciences:
n MAC Mentoring Keynote— Diversity in Biomedical Research and
Professional Development, Isiah M. Warner (Video)
n MAC Seminar—Strategies and Tactics of Grantsmanship, Beth Schachter
(Video)
n MAC Presentation—Expectations of the Undergraduate Years to the
Preliminary Examination, Andrew G. Campbell, Michael J. Leibowitz (Audio)
n E.E. Just Lecture—From Silent Spring to Silent Night: What Have We
Learned? Tyrone B. Hayes (Video)
n WICB Workshop— Leveraging Your PhD in the Real World, Vivian Siegel,
Junying Yuan, Yi Kong, Jeremy Paul, Beth Schachter, Eric Vieira, Joanna M.
Watson (Video)
n Career Program—One Job Title, Many Tracks: How to Prepare for the
Academic Career That Best Suits Your Interests, Anthony J. Koleske, Kathy T.
Schmeidler, Michael J. Wolyniak (Video)
34
year experiment. That successful experiment
led to the creation of the Coalition for the
Life Sciences (originally the Joint Steering
Committee for Public Policy) and the
establishment of the Congressional Biomedical
Research Caucus and the Congressional Liaison
Committee.
Pollard also looked forward and identified
four problems standing in the way of continued
success in science policy advocacy:
1. The loss of science policy champions in the
U.S. Congress
2. The current state of the U.S. economy
3. Re-emerging cultural wars
4. Unsustainable science funding models
Looking forward, Pollard has one goal: to
make biological science advocacy efforts 1% as
successful as NRA advocacy efforts.
Doug Koshland, the new chair of the ASCB
Public Policy Committee, has a suggestion for
reaching that goal: Scientists should be more
like Pollard. In his introduction, Koshland said
that, like Pollard, the scientific community
approaches problems with energy, believes that
individuals can solve problems, and doesn’t
give up. In short, Koshland said, “we all have
an inner Tom Pollard. If we tapped our inner
Tom Pollard and used it for public service, our
biological community would be a better place.”
—Kevin M. Wilson
Doug Koshland (left) presented the
2010 ASCB Public Service Award to
Tom Pollard for years of dedicated
service to the ASCB and the scientific
community at large, pioneering
leadership in grassroots scientific
advocacy, and effective congressional
education.
ASCB Annual Meeting
MAC poster presenters Joy Marshall
(left) and Starlette Dossou
Joan Brugge, Susanne Pfeffer, Susan Michaelis,
Elaine Fuchs, Marc Kirschner
A microscopic image on a huge screen in the Exhibit
Hall fascinated visitors.
Daniele Ejzykowicz, Lucy Caudillo, Alina De La
Mota-Peynado
James Jamieson, Tim Mitchison
Lisa Gurski and Tyler Drake helped distribute
ASCB 50th Anniversary t-shirts at the ASCB
Booth
Liwei Jia (left) was delighted to be “ROCK’d” by ASCB
staff (right) as an exhibitor looked on.
Patty & Tom Pollard, Joe Gall
Meeting attendees pour into a session
Ani Saraswathula from Georgetown University at the
Undergraduate Poster Session
For more photos, visit www.ascb.org, click on “Photos from the 50th Annual Meeting”.
35
Congress 101
Based on the title of this session, you would
assume that the majority of the discussion
focused around the goings-on
in Washington, DC. However,
a great deal of the talk centered
around the wide variety of
opportunities that everyday
scientists have to influence
lawmakers’ conversations
regarding the funding of
biomedical research. Decisions
made by the legislature on
behalf of their constituency
Left to right: Then Public Policy Committee
directly impact our work. This
Chair Tom Pollard, Martin Chalfie, and 2008
is through both establishment
ASCB President Bruce Alberts discussed the
of budgets for the U.S. National
importance of scientists being involved in
Institutes of Health (NIH) and
science policy advocacy.
the National Science Foundation
(NSF) and through regulations
that steer the sorts of projects
that can be funded by federal
dollars. Bruce Alberts, Martin
Chalfie, and then Public Policy
Committee Chair Tom Pollard
led the discussion. Coalition for
the Life Sciences (CLS) Director
Lynn Marquis and ASCB Public
Policy Director Kevin Wilson
were also on the panel.
Tom Pollard (left) and 2010 ASCB President
Tim Mitchison (right) listened to Public Policy
Participating in the
Committee member Connie Lee (center) detail
conversation
takes as little
her first visit to Capitol Hill.
effort as sitting down and
writing a letter. As is usually
the case, increased effort often leads to a greater
likelihood of success. The panelists discussed
the benefits of writing letters and making phone
calls to congressional offices. They noted that
sustained and continued effort can have more
impact than occasional contact. There was
even a discussion of how to get the “personal
effort” to come through in our digital world.
(For example, send a PDF file of a handwritten
letter or “typed” letter on letterhead as an email
attachment.)
Since lawmakers are making choices on
behalf of their constituents, the panels and
audience noted that it is equally important
for Congress to realize two things. First, their
districts benefit directly from federal funding of
basic research since their constituents include
scientists funded by NIH and NSF grants.
Second, funding of biomedical research is of
benefit to their other, nonscientist constituents
36
through the progress made by scientists and the
application of those discoveries.
One method discussed to make lawmakers
aware of the impact of science on their
constituency was to educate the public on the
impact of federally funded basic research on their
lives. Contributions to Op/Ed pages of the local
newspaper and “science cafés” were two examples
of outreach events that could raise awareness about
the local impacts of federally funded science.
Additionally, the panelists informed the
audience about other ways to make a direct
impact, including joining the CLS, applying for
American Association for the Advancement of
Science policy fellowships, and participating in
CLS-sponsored Capitol Hill Day events. Those
who were interested were encouraged to attend
the “Politicians Don’t Bite” panel discussion for
first-hand accounts from scientists who chose to
get involved.
—Omar A. Quintero, Penn State College of
Medicine
Politicians Don’t Bite
Coalition for the Life Sciences (CLS) Capitol
Hill Day visits to Congress provide scientists
with a chance to make their concerns known
in Washington, DC. In the “Politicians Don’t
Bite” panel discussion, Connie Lee, 2010 ASCB
President Tim Mitchison, Tom Pollard, and Gary
Ward described their personal experiences in
science advocacy on Capitol Hill Days. Although
each panelist had a unique story to tell, they all
felt as though their contributions mattered.
The panelists indicated that over the years,
the CLS has become adept at preparing a
visiting scientist to be an effective educator
and advocate for federally funded science.
They mentioned that although it is often a
congressional staff member rather than the
elected representative who meets with the
scientists, staffers are important to the legislative
process and are often very excited to spend a few
minutes talking to scientists—a rare breed on
the Hill. A meeting with a congressional staff
member gives scientists a unique opportunity
to have the ear of the person in the office who
is most keenly focused on issues involving
science. The panelists also made it apparent
that scientists taking part in outreach efforts
are active participants in the process. On such
visits, the scientists “talk science,” demonstrating
the direct consequences of federal funding on
constituents. CLS staff attend the meetings
to help tie current issues related to continued
funding of science to the progress of the research
effort the scientist has discussed.
The panelists discussed with the audience
other options for active participation in science
advocacy. In addition to phone calls, letters,
and visits to the offices of their legislators
in Washington, the panelists and CLS staff
suggested that scientists visit the local offices of
legislators and consider inviting their legislator
and his or her staff to visit a functioning
research lab so they can see federal funding
in action. Scientists do not have to undertake
these tasks on their own. Just as the CLS staff is
involved in the planning and implementation of
Capitol Hill Day events, they are also available
to help scientists approach their legislators and
get a local outreach event scheduled.
The panelists’ Capitol Hill Day experiences
highlighted one method of developing
relationships that would benefit scientists
by putting a constituent’s face to what may
not seem like a local issue to a legislator. In
combination with other outreach efforts, the
Capitol Hill Day visits are part of the calculus
of decision-making, and every little bit counts
when trying to positively influence Congress’
attitude toward science.
—Omar A. Quintero, Penn State College of
Medicine
Women in Cell Biology Committee Events
WICB Workshop
Women in Cell Biology (WICB) Committee
members Vivian Siegel, Vanderbilt University,
and Junying Yuan, Harvard Medical School,
moderated a 90-minute panel discussion on
“Leveraging Your PhD in the Real World.” More
than 60 graduate students, postdocs, and faculty
members attended. Panelists included: Yi Kong,
GlaxoSmithKline; Jeremy Paul, Skirball Institute
of Biomolecular Medicine, New York University
School of Medicine; Beth Schachter, consultant,
Scientist-to-Scientist Communications; Eric
Vieira, Mount Sinai School of Medicine; and
Joanna M. Watson, National Cancer Institute.
Participants learned about:
n Common motivations for looking outside
academia for career options
n How to use informational interviews to
research possible career options
n The difference between a CV and a résumé
n Other skill sets that may prove valuable to get
a first job
n Ways to get comfortable speaking and
interviewing
Toward the end of the session, questions
were welcomed from the participants, and
panelists remained after the session to speak
more informally with participants. A videotape
is available (see p. 34).
—Vivian Siegel on behalf of the WICB Committee
WICB Network Reception—
Standing Room Only
The Women in Cell Biology (WICB)
Committee hosted its annual and growing
reception in Philadelphia. More than 70
attendees represented a wide spectrum from
undergrad and grad students, postdocs, support
scientists, professors, to a department chair
whose goals overlapped with various current
WICB activities. After a brief summary from
Chair Sandra Masur, Committee members
voiced their ideas for new initiatives and
also their appreciation for the WICB. The
opportunity to network productively was
enjoyed by all over the next hour until people
hurried off to hear more cell biology. To join the
WICB Network and get periodic updates on
issues of interest, go to: http://ascb.org/index.
php?option=com_content&view=article&id=29
0&Itemid=152.
—Sandra Masur on behalf of the WICB
Committee
Left to right: WICB Workshop panelists:
Junying Yuan, Yi Kong, Joanna Watson,
Beth Schachter, Eric Vieira, Jeremy
Paul, and Vivian Siegel
Attendees at the WICB Workshop
37
Career Discussion & Mentoring
Roundtables
The Career Discussion & Mentoring
Roundtables continue to be a highlight
for women and men at the ASCB Annual
Meeting. For the second year in a row, over 700
people registered, reflecting the undiminished
enthusiasm and growing response of both
attendees and table leaders.
Table leaders included outstanding ASCB
scientists as well as generous representatives
from biotech, patent law, and scientific writing/
editing, heading a total of 70 roundtables.
Colleagues in the Philadelphia area were very
helpful in recruiting additional table leaders
with expertise in biotech and patent law. The
most popular topics continue to be Biotech and
Pharmaceuticals, Obtaining an Appropriate
Postdoc Position, Developing Your Career,
Job Application Strategies for Academic
Positions, Teaching and Research in Primarily
Undergraduate Institutions, and Scientific
Writing or Editing. Newly popular this year
was For Undergraduates, What Comes Next?
Discussions were lively, interactive, and highly
informative. Email addresses were exchanged for
continued networking and mentoring.
One attendee wrote that “…[The table
leaders]… were so incredibly charming and
thoughtful with their knowledge and experience.
They discussed specifics and generalities, they
were patient, kind, and generous with the
questions posed to them. I am very grateful to
them and to the WICB for the privilege of this
quality time with two such fantastic scientists.”
WICB Chair Sandy Masur
welcomed more than 700
participants to the Career
Discussion.
A full house at the Career Discussion & Mentoring
Roundtables
It was also clear that the table leaders felt
that this was a wonderful event for them
at the Annual Meeting. So next year, when
you register for the meeting, sign up to be
mentored or consider volunteering to be a table
leader to mentor in a topic in which you have
expertise. n
—Sandra Masur on behalf of the WICB
Committee
MAC Funding Available
The ASCB Minorities Affairs Committee (MAC) is accepting applications for the following
programs (Deadline: March 31, 2011):
n ASCB MAC Visiting Professorship Awards Program: This program provides research
support for professors at minority-serving institutions to work in the laboratories of members
of the ASCB for an eight- to 10-week period during the summer of 2011.
n ASCB MAC Linkage Fellows Program: The purpose of this awards program is to increase
participation of faculty from minority-serving institutions to serve as a link between the
institution, its students, faculty, and administration and the ASCB MAC.
Funding is provided by a grant from the Minorities Access to Research Careers (MARC)
program of the National Institute of General Medical Sciences.
For more information, visit www.ascb.org, click on “Committees,” then “Minorities
Affairs.” Questions? Contact Senior Manager, Minorities Affairs, Deborah McCall at
[email protected]. n
38
ASCB Exhibitor Advisory Committee
The second annual meeting of the ASCB
Exhibitor Advisory Committee (EAC) was held
in Philadelphia. Committee members present
were Ingrid Benirschke, Cold Spring Harbor
Laboratory; Bjørn Henriksen, Axis-Shield PoC;
Chuck Locke, Drummond Scientific; Graham
Long, TGR Biosciences; and Paul Millman
(Chair), Chroma Technology.
The EAC was established to enhance
the relationship between ASCB and its
exhibitors. The Committee enables exhibitors
to voice ideas and concerns; participate in
the assessment of the ASCB, its vendors, and
technologies; and serve in an advisory capacity
to the ASCB.
Among the topics discussed were:
n Exhibitors’ Philadelphia experience: What
worked or did not work for exhibitors on
the floor? How can Philadelphia improve?
How can the ASCB assist?
n The exhibitor registration process
n 2010 Exhibit Hall layout and discussion for
2011
n The online exhibitor service kit
n How can ASCB’s contractor (Freeman)
better serve exhibitors?
n The introduction of ASCB’s new housing
partner onPeak and why exhibitors should
book within the housing block
n ASCB’s Newsroom and how exhibitors can
use it to their advantage
n How exhibitors can assist the ASCB Public
Policy Committee in educating Congress
and its staff on the importance of increased
funding for the National Institutes of Health
and the National Science Foundation.
Lack of funding affects exhibitors as well
as scientists. For more information contact
Kevin Wilson ([email protected]).
n The 2011 Annual Meeting in Denver
The ASCB wishes to thank its special
invited guests: Theresa Blankenau, Convention
Services Manager, Visit Denver; Greg Burton,
onPeak; Chuck Dennis and Parcival Lie of
Convention Data Services; Jack Ferguson,
President of the Philadelphia Convention
and Visitors Bureau; Larry Gutelius, National
Sales Manager, Freeman; Jim Lewis, General
Manager Pennsylvania Convention Center
Authority; Arlaina McDaniel, Colorado
Convention Center, CSM; and Philomena
Petro, Vice President, Philadelphia Convention
and Visitors Bureau. The meeting was also
attended by ASCB staff John Fleischman,
Science Writer; Ed Newman, Director of
Exhibits and Sales, Trina Armstrong, Director
of Meetings; and Kevin Wilson, Director of
Public Policy.
The ASCB especially thanks EAC members
Beth Banes of Flexcell International Corp;
Chuck Locke of Drummond Scientific; Karen
Phillips of Olympus America, Inc.; and Ingrid
Benirschke, CSHL Press for their advice
and guidance regarding the ASCB exhibit
regulations, practices, opportunities, and
communications.
The EAC is seeking additional
representatives from the publishing industry
to serve one- to three-year terms; both small
and large exhibiting companies are encouraged
to apply. To request information or to be
considered for the Committee, contact eac@
ascb.org. n
—Trina Armstrong
Scenes from the Exhibit Hall
40
PUBLIC POLICY Briefing
Not Exactly New Faces in Town
Rogers, Hall, and Ryan. It’s not the name of a
law firm. They are the new chairs of important
congressional committees for researchers
funded by the U.S.
National Institutes
of Health (NIH)
or the National
Science Foundation
(NSF).
Harold Rogers
(R-KY) will
Ralph Hall
Harold Rogers
chair the House
Appropriations Committee. He has served
in Congress for 30 years. Ralph Hall (RTX), the new chair of the House Science and
Technology Committee, is 88 years old and
has the unique distinction of having been both
a Democrat and a Republican. Paul Ryan (RWI) will chair the House Budget Committee.
Ryan was 11 when Hall and Rogers were first
elected to Congress.
In the U.S. Senate, Daniel Inouye (D-HI)
will remain chair
of the U.S. Senate
Appropriations
Committee, and
John Rockefeller
(D-WV) continues
as chair of the U.S.
Senate Commerce,
Paul Ryan
Science, and
Transportation Committee. Kent Conrad (DND) remains chair of the U.S. Senate Budget
Committee.
If these Representatives and Senators
represent you, please contact them and
introduce yourself and your research. n
—Kevin M. Wilson
“Senator Waste”
U.S. Senator Tom Coburn (R-OK) despises
government waste. In an effort to highlight
federal government spending he considers
wasteful, Coburn issues occasional reports
detailing examples of unnecessary spending by
various government agencies.
His most recent report, Wastebook 2010, A
Guide to Some of the Most Wasteful Government
Spending of 2010, details 100 examples of what
the Senator considers to be needless federal
spending. Three of Coburn’s examples involve
U.S. National Institutes of Health (NIH)
funding.
Two of the NIH programs highlighted by
the Senator are grants that had been approved
by NIH peer review. The two grants, Diffusion
of HIV-1 Among Drug Using Men in SE Asia
and Community-Based HIV VCT: South Africa,
were described in the Wastebook 2010 book
as “Studying Male Prostitutes in Vietnam”
and “Teaching South African Men How to
Wash Their Genitalia,” respectively. The third
program mentioned by Coburn is funding
to promote HIV Vaccine Awareness Day.
This project is described as “NIH Promotes
Awareness for Non-Existent Vaccine.”
Congressional criticism of NIH-funded
grants is nothing new. The House of
Representatives has even voted to defund
some grants in the past based on sensationalsounding grant titles. In 2007, the House of
Representatives was debating amendments
to defund a number of sensational-sounding
grants. Former Representative David Obey (DWI), then Chair of the House Appropriations
Committee, criticized efforts to defund
individual grants. Obey said, “the day we decide
which grants are going to be approved on the
basis of a 10-minute horseback debate in the
House of Representatives…that is the day we
will ruin science research in this country. We
have no business making political judgments
about those kinds of issues.”
To read Coburn’s report, go to http://tinyurl.
com/Wastebook10. n
—Kevin M. Wilson
41
New Twist on Peer Review
Who says scientists should be the only ones
deciding which research grant applications
receive federal money? The new leadership of
the U.S. House of Representatives is asking
citizens to review grants funded by the National
Science Foundation (NSF).
The new Republican majority has launched
a website seeking comments from the public on
where cuts can be made to the federal budget.
The website, You Cut: Changing the Culture
in Washington, allows citizens, according to the
website, “to vote, both online and on your cell
phone, on spending cuts that you want to see
the House enact.”
The NSF is one of the first federal programs
highlighted on the You Cut website. With the
help of a video introduction by Representative
Adrian Smith (R-NE), visitors to the You Cut
website are asked to review grants awarded by the
NSF. As Rep. Smith says in his introduction, “I’m
asking your assistance. Help us identify grants that
do not support the hard sciences or which you
don’t think are a good use of taxpayer dollars.”
Website visitors are asked to visit the NSF
grant database and search for grants. The You
Cut website even suggests that visitors use
keywords, including success, culture, media,
games, social norm, lawyers, museum, leisure,
and stimulus, to highlight certain grants. After
reviewing the grants, participants are asked
to send their email address, the grant award
number, and their personal comments to the
House Republican leadership.
To review the entire You Cut website, go to
http://majorityleader.gov/YouCut. The NSF
section can be found at http://majorityleader.
gov/YouCut/Review.htm. Readers may want to
note the value of peer review and NSF funding
in response. n
—Kevin M. Wilson
You’re a biologist,
not a mechanic
Upgrade to the Agilent MLC400
monolithic laser
combiner and say
goodbye to laser
alignment. Forever.
Zero adjusting. More imaging.
Say goodbye to laser alignment 1-800-829-4444 ext. 2580
42
2011 Call for Nominations
Bruce Alberts Award for Excellence in Science Education
Who is Eligible: An individual who has demonstrated innovative and sustained
contributions to science education, with particular emphasis on the broad local, regional,
and/or national impact of the nominee’s activities. Nominators must be ASCB members,
but the candidate and support letter authors need not be.
How to Apply: Provide a letter of nomination, a maximum of three letters of support,
and CV.
Awards: The winner is presented a plaque and will give remarks at the Annual Meeting.
Many expenses to attend the Annual Meeting are paid.
Public Service Award
Who is Eligible: An individual who has demonstrated outstanding national leadership in
support of biomedical research. Nominators must be ASCB members. The award winner
may, but need not, be a scientist.
How to Apply: Provide a letter of nomination with a description of the nominee’s
advocacy for, and promotion of, scientific research.
Awards: The winner gives the Public Service Award Lecture at the ASCB Annual Meeting
and receives a certificate. Many expenses to attend the Annual Meeting are paid.
Deadline: March 31 (electronic submission preferred)
Early Career Life Scientist Award
Who is Eligible: An outstanding scientist who has served as an independent investigator
for no more than seven years as of March 31.
How to Apply: Provide a nominating package that includes CV, brief research statement,
nominating letter, and no more than three letters of support (at least one of which must
come from outside the nominee’s institution). Nominators must be ASCB members.
E.B. Wilson Medal
Who is Eligible: An individual who has demonstrated significant and far-reaching
contributions to cell biology over a lifetime in science. Nominators must be ASCB
members, but the candidate need not be.
How to Apply: Provide the candidate’s CV and no fewer than three, and no more than
five, letters of support.
Awards: The winner is presented a plaque and an honorarium and will speak in a
Minisymposium at the Annual Meeting. Many expenses to attend the Annual Meeting are
paid.
Awards: The winner of the ASCB’s highest honor for science gives the E.B. Wilson
Lecture at the Annual Meeting and receives the E.B. Wilson Medal. Many expenses to
attend the Annual Meeting are paid.
Merton Bernfield Memorial Award
E.E. Just Lectureship
Who is Eligible: A minority scientist who has demonstrated outstanding scientific
achievement. Nominators must be ASCB members, but the candidate need not be.
How to Apply: Provide a nomination package that includes a CV and a letter describing
the nominee’s scientific achievement and mentoring support of underrepresented minority
students and scientists.
Awards: The winner gives the E.E. Just Lecture at the Annual Meeting and receives a
plaque and a medal. Many expenses to attend the Annual Meeting are paid.
Who is Eligible: An outstanding graduate student or postdoctoral fellow (at the time of
nomination) who has excelled in research
How to Apply: The student or postdoc or his or her advisor should submit a one-page
research statement, a CV, a list of publications, a copy of the abstract submitted to the
current year’s Annual Meeting, and the advisor’s letter of recommendation. Postdocs may
also submit the recommendation of their graduate student advisor. Duplicate applications
from graduate students may be submitted for the Gilula and Bernfield Memorial Awards.
Nominators must be ASCB members.
Awards: The winner is presented a plaque an honorarium and will speak at a Minisymposium
at the Annual Meeting. Many expenses to attend the Annual Meeting are paid.
Deadline: July 15 (electronic submission preferred)
WICB Career Recognition Awards
Norton B. Gilula Memorial Award
Who is Eligible: For the Junior Award, a woman in an early stage of her career (generally less
than five years in an independent position at the time of nomination) who is making exceptional
scientific contributions to cell biology and exhibits the potential for continuing a high level of
scientific endeavor and leadership; for the Senior Award, a woman or man in a later career stage
(generally full professor or equivalent) whose outstanding scientific achievements are coupled
with a long-standing record of support for women in science and by mentorship of both men and
women in scientific careers.
Who is Eligible: An outstanding graduate or undergraduate student (at the time of
nomination) who has excelled in research or first-year postdocs whose work was performed
while a PhD or MD/PhD
How to Apply: For the Junior Award, provide a letter of nomination, CV, and no more than
three letters of support, at least one of which must come from outside the nominee’s institution.
For the Senior Award, provide a letter of nomination, CV, and no more than five letters of
support, at least one of which must come from outside the nominee’s institution, to include
two letters from those who have been mentored by the candidate, mentioning specifics of the
nominee’s mentoring history. Nominators must be ASCB members.
How to Apply: The student or advisor should submit a one-page research statement,
a CV, a list of publications, if any, the abstract submitted to the current year’s Annual
Meeting, and the advisor’s letter of recommendation. Duplicate applications from graduate
students may be submitted for the Gilula and Bernfield Memorial Awards. Nominators
must be ASCB members.
Awards: The winners are presented an honorarium and plaque at the Annual Meeting. Many
expenses to attend the Annual Meeting are paid.
Awards: The winner is presented a plaque and a ribbon for his/her poster board. Many
expenses to attend the Annual Meeting are paid. Funded by an annual grant from
Rockefeller University Press.
Deadline: March 31 (Send electronic submissions only to Cheryl Lehr at [email protected])
Deadline: July 15 (electronic submission preferred)
All electronic applications and nominations should be submitted to [email protected]. Or mail to:
[email protected]
For names of prior awardees or more information, visit www.ascb.org and click on “Awards/Grants,” or contact the ASCB at 301-347-9300 or [email protected].
43
HIGHLIGHTS from MBoC
The Editorial Board of Molecular Biology of the Cell has highlighted the following articles from
the December 1 and 15, 2010, and January 1 and 15, 2011, issues. From among the many fine
articles in the journal, the Board selects for these Highlights articles that are of broad interest
and significantly advance knowledge or provide new concepts or approaches that extend our
understanding.
Microautophagy of the nucleus coincides with a vacuolar
diffusion barrier at nuclear–vacuolar junctions
Rosie Dawaliby and Andreas Mayer
Nuclear-vacuolar (NV) junctions are organelle contact sites
in yeast. They exclude nuclear pores from the organelle
interface. On the vacuolar side, a lipid-dependent process
excludes specific membrane proteins, such as V-ATPase, from
the contact site. This suggests that NV junctions establish
selective diffusion barriers.
Mol. Biol. Cell 21 (23): 4173–4183
AS160 associates with the Na+,K+-ATPase and mediates
the adenosine monophosphate–stimulated protein kinase–
dependent regulation of sodium pump surface expression
Daiane S. Alves, Glen A. Farr, Patricia Seo-Mayer, and Michael
J. Caplan
The sodium pump interacts with AS160, a protein that
regulates the trafficking of the GLUT4 glucose transporter. This
interaction drives the internalization of the sodium pump from
the cell surface, and this process is in turn controlled by the
energy-sensing kinase adenosine monophosphate-stimulated
protein kinase.
Mol. Biol. Cell 21 (24): 4400–4408
Finding the cell center by a balance of dynein and myosin
pulling and microtubule pushing: a computational study
Jie Zhu, Anton Burakov, Vladimir Rodionov, and Alex Mogilner
Light micrograph of the photoreceptor layer of a mouse retina (left) and an electron
micrograph of the transition zone of the cilium of a mouse photoreceptor cell (right).
(Image: Vanda Lopes and Conchi Lillo, University of California, Los Angeles, School of
Medicine and University of California, San Diego, School of Medicine)
By comparing computer modeling predictions with
observations, we conclude that strong dynein and weaker
myosin-generated forces pull the microtubules inward,
competing with microtubule plus-ends pushing the
microtubule aster outward. The balance of these forces positions the centrosome at the cell center.
Mol. Biol. Cell 21 (24): 4418–4427
NOA1 is an essential GTPase required for mitochondrial protein synthesis
M. Kolanczyk, M. Pech, T. Zemojtel, H. Yamamoto, I. Mikula, M.-A. Calvaruso, M. van den Brand,
R. Richter, B. Fischer, A. Ritz, N. Kossler, B. Thurisch, R. Spoerle, J. Smeitink, U. Kornak, D. Chan,
M. Vingron, P. Martasek, R. N. Lightowlers, L. Nijtmans, M. Schuelke, K. H. Nierhaus, and S. Mundlos
Nitric oxide associated-1 (NOA1) is an evolutionarily conserved guanosine triphosphate binding protein that
localizes predominantly to mitochondria in mammalian cells. Here we determine NOA1 function through
generation of knock-out mice and in vitro assays.
Mol. Biol. Cell 22 (1), 1–11
CDase is a pan-ceramidase in Drosophila
C. Yuan, R. P. Rao, N. Jesmin, T. Bamba, K. Nagashima, A. Pascual, T. Preat, E. Fukusaki, U. Acharya, and
J. K. Acharya
It is demonstrated that the Cdase gene encodes all measurable ceramidase function in Drosophila. BWA,
an alkaline ceramidase homologue, does not exhibit ceramidase activity. Bwa genetically interacts with other
ceramide-metabolizing enzymes by influencing the flux through the sphingolipid pathway.
Mol. Biol. Cell 22 (1), 33–43
44
Actin cables and the exocyst form two independent morphogenesis pathways in the fission yeast
F. O. Bendezú and S. G. Martin
In fission yeast, long-range transport and vesicle tethering by the exocyst are individually dispensable
but together essential for cell morphogenesis. Both pathways function downstream of Cdc42. The exocyst
localizes to growing cell tips independently of the cytoskeleton and instead depends on PIP2.
Mol. Biol. Cell 22 (1), 44–53
A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
N. Cremona, K. Potter, and J. A. Wise
Analyses of 32 meiotic genes from fission yeast with respect to nascent transcription, RNA processing/
accumulation, and effects of surveillance factor mutants reveal that the vast majority are “on” in proliferating
cells and less than one-third show a transcriptional peak during meiosis, highlighting the important
contribution of RNA-level regulation.
Mol. Biol. Cell 22 (1), 66–77
A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
X.-W. Chen, D. Leto, T. Xiong, G. Yu, A. Cheng, S. Decker, and A. R. Saltiel
It is shown that RalA is regulated by a Ral GAP complex (RGC 1/2) in insulin action and links PI 3-kinase
signaling to RalA activation. Akt phosphorylates the complex and inhibits its function, resulting in increased
RalA activity and glucose uptake.
Mol. Biol. Cell 22 (1), 141–152
Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments
A. Lorente-Rodríguez and C. Barlowe
The role of specific membrane lipids in ER–Golgi transport is unclear. Using cell-free assays that measure
stages in ER–Golgi transport, a variety of enzyme inhibitors, lipid-modifying enzymes, and lipid ligands were
screened. The results indicate that PI(4)P is required for SNARE-dependent fusion of COPII vesicles with the
Golgi complex.
Mol. Biol. Cell 22 (2), 216–229
Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility
N. Cernotta, A. Clocchiatti, C. Florean, and C. Brancolini
Histone deacetylase 4 (HDAC4) controls several cellular responses and is subjected to multiple levels of
regulation. Here it is shown that HDAC4
is under the regulation of the proteasome,
in a growth factor– and GSK3β-dependent
manner. Degradation of HDAC4 could
contribute to the attenuation of random cell
motility observed in cells in the G0 phase of
the cell cycle.
Mol. Biol. Cell 22 (2), 278–289 n
Model of the hexameric cleavage stimulation factor, which is involved in 3′ end
processing of vertebrate mRNAs. (Image: Nicole Kleinschmidt, University of Berne)
45
Hot off the Press Book: Classroom
Uses for the ASCB’s Annual Guide
for Science Reporters
We don’t think
the average ASCB
member is aware of
the press book, why
we produce it, or
how it might be used
in the classroom
as a resource.
46
Like the proverbial iceberg, there is more than
meets the eye at the ASCB Annual Meeting. The
visible tip of posters, talks, and Symposia floats
on a mass of support activities including those
of the Public Information Committee (PIC).
Each year PIC conducts a public outreach
operation aimed at journalists covering breaking
science news at the Annual Meeting. The PIC’s
annual press book is a media-friendly guide
to the Annual Meeting, highlighting a dozen
or so “top pick” stories chosen by Committee
members in three rounds of peer screening from
all abstracts submitted for Minisymposium
presentations. And after the press book has
fulfilled its initial purpose, it may have a second
life as an educational resource.
A month before the start of the Philadelphia
meeting, Cell Biology 2010, the press book for
the 50th Annual Meeting, was released under
a special embargo to roughly 1,000 news
organizations and journalists who received a
preview of the meeting in return for agreeing
not to publish, broadcast, or post anything
about the stories until the day of the actual
talks. Cell Biology 2010 was delivered a printed
magazine, a downloadable PDF, and a series of
press releases.
The media response to Cell Biology 2010
and the cell biology news that it promoted was
excellent. But reporters are only one possible
audience for the ASCB media guide. The PIC
wants to promote an educational afterlife for Cell
Biology 2010 in classrooms, says PIC Chair Simon
Atkinson. Cell Biology 2010 is now freely available
at www.ascb.org/pressbook/2010/embargo/
pressbook.html, and biology teachers looking for
novel classroom tools should take note.
“We don’t think the average ASCB member
is aware of the press book, why we produce it,
or how it might be used in the classroom as a
resource,” says PIC Chair Simon Atkinson. “The
PIC works hard to ensure that press book stories
are carefully selected, edited, and then corrected
by the scientists involved. The press book shows
research science as a process in which scientific
meetings like ours play a vital role.” Atkinson
is asking ASCB members, especially those who
teach undergraduates, to consider possible uses
for Cell Biology 2011 in the classroom.
Karen Kalumuck, Staff Biologist at the San
Francisco Exploratorium’s Teacher Institute and
a member of the ASCB’s Education Committee,
was given an early look at Cell Biology 2010.
Kalumuck believes that, “Any of these articles
would be excellent supplements for an upperlevel cell biology class in college but also in high
schools. This is a wonderful opportunity to read
about hot-off-the-presses research (with the
caveat that it’s not been published yet).” (See p.
47 for Kalumuck's comments on two stories of
particular interest.)
Kalumuck continues, “Reading about
research in this form is a wonderful opportunity
to emphasize an important part of the process
of science: that results are presented to peers—
sometimes before publication—to stimulate
discussion, get advice, form collaborations,
etc., as is the case here. However, these research
results have not gone through the peer review
process that is key to publication in a journal.
It's an interesting peek into the process of
science, and how science is actually quite a social
endeavor, contrary to the stereotypical image of
a solitary scientist slaving away in a lab.”
Comments, suggestions, and reports on the
success—or failure—of Cell Biology 2010 as an
educational tool are welcome, says Atkinson.
Contact him at [email protected] or ASCB
Science Writer John Fleischman at jfleischman@
ascb.org. n
—John Fleischman
Cell Biology 2010 Top Pick Educational
Resources
Karen Kalumuck, Staff Biologist at the San Francisco Exploratorium’s Teacher Institute and a member of the ASCB’s Education
Committee, picked two stories from Cell Biology 2010 of particular interest to the nonscience major, early biology major, or
even high school student. Here are her comments:
The Science of Pomegranate Juice in a Swirl (page 2)
This story—which describes the search for active ingredients in pomegranate juice that may have a molecular impact on
metastatic prostate cancer cells—is easily approachable. Pomegranate juice, extracts, and teas are everywhere! It’s always
interesting to see the impact that science can have on products and advertising. This article also brings in “science and society”
issues. The recent brouhaha between the Federal Trade Commission and juice maker Pom Wonderful over Pom’s claims about
the health benefits of pomegranate products could be the basis of a great discussion about the sort of information that we need
to make informed decisions—and to not buy claims without evidence. Surely nearly everyone knows or knows of someone who
has had prostate cancer. The findings here could also provide an opportunity to discuss the use of model organisms, why we
use them, and their limitations. Discussing the characteristics of cancer cells is also a great way to get at aspects of normal cell
function, such as cell cycle and mitosis.
Clearing the Way in Huntington’s Disease (page 11)
Huntington’s disease has long been used as an example of a human autosomal dominant disorder. The detail here about its cause
at a molecular level is quite useful to any class that is trying to couple “classic” inheritance patterns with the molecular basis
of disease. The increased biogenesis of the mitochondria is fascinating, and how this seems to help in mice is a nice story. The
potential to also help Alzheimer’s and Parkinson’s disease sufferers could also stir broader interest. This could easily be inserted
into either a genetics or a neurosciences part of a course. n
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47
LETTER to the Editor
To the Editor,
As a European/German cell biologist, I read the article of Tony Hyman (October 2010 ASCB
Newsletter) with great interest, where he compared the systems in the U.S. and in Europe.
Unfortunately, Tim Mitchison selected [as a guest author] a renowned and excellent scientist,
who does know a lot about the top research institutes in Europe, but apparently little about the
recruitment system and the life within the University, which provides most of the training of young
group leaders. Hyman was for nine years at EMBL, an outstanding research institute with almost no
teaching obligations, and moved on as a director to the Max Planck Society—again with almost no
teaching obligations and a guarenteed budget and positions. The result is a very research-oriented
view on career, which ignores a couple of important parameters: funding and teaching.
Funding
As a young scientist in Europe (and let’s take Germany as an example), you have to apply for
funding once you receive a starting position. Jobs at Max Planck and EMBL are scarce and hard
to get. I know many excellent people who did not fit the scheme at that time and did outstanding
research at universities. In general, other grant-funded positions at universities are funded for three
plus two years, sometimes slightly longer. However, the nine-year frame as described by Hyman
is only given at the EMBL, and does not apply to universities. We fortunately have the German
research council (DFG), which is an excellent organization with a very fair reviewing process and a
good success rate.
Teaching
German scientists have to show teaching experience in order to qualify for a position as a professor.
In fact, they have to reapply for a position after their group leader career (usually five years).
Teaching can be distracting from science, in particular at the beginning of your independent career,
and so often kept to a minimum at research institutes like Max Planck and EMBL. If you have a
full-professor position, teaching includes the undergraduate level with up to 200 students, as well
as practical courses. In contrast, group leaders at EMBL or Max Planck sometimes organize courses
for graduate students, which are usually close to their research. Undergraduate teaching is, however,
often avoided. Thus, applications from group leaders from these institutes for professorships
in Germany are sometimes considered with caution as they may be excellent researchers, but
sometimes have very little to no experience in organizing an important part of their future job as a
university professor. I heard that this is slightly changing, but the teaching load at Max Planck is still
very moderate.
Of course, it would be excellent to have more U.S. scientists move to Germany, also to perform
their postdocs abroad. And I appreciate it that Hyman had the chance to compare the systems more
globally, which he did well from his perspective. However, it is not quite as simple as it seems from
the view point of a Max Planck director. n
—Christian Ungermann, University of Osnabrueck, Germany
Response from Tony Hyman: Christian Ungermann makes an excellent point that the bulk of the
research is in the universities, which also do the majority of the teaching. Indeed it is unfortunate that the
research institutes have become separated from teaching in Europe. This is another way in which the U.S.
system is still superior to the European system. Generally, in the U.S. research and teaching are embedded
in the same institution. I was trying to write from the point of view of an American coming to Europe—
normally Americans are excluded from the university system because of the language requirement and
therefore end up at one of the research institutions such as EMBL or Max Planck, which have a nine-year
perspective on research. 48
WOMEN in Cell Biology
Strategies and Tactics of
Grantsmanship
overarching need to support the mission of
the agency. Program officers, who typically
are trained scientists themselves, will give you
guidance about matters such as the timeliness
and perceived significance
of your plan and the study
section to which you should
direct your proposal. Get
to know your program
officer long before you
submit your application.
Indeed, once you’ve devised
a rough draft “specific
aims” section, contact your
program officer by email,
including the aims section
as an attachment, and
set up a time for a phone
conversation.
4. Familiarize yourself with the criteria
that each funding agency uses to assess
proposals. Then shape your proposal so
that reviewers can readily see that you have
addressed these criteria. For example, NIH has
reviewers assess the proposals based on specific
criteria: significance, approach, innovation,
investigator, and environment. NSF, which has
both a scientific and an educational mandate,
has reviewers assess proposals for two general
criteria: scientific merit and broader impact.
The second criterion refers to ways in which
the proposed work, as well as its outcome, will
educate and train the general population as
well as future scientists. To learn more about
these review criteria, visit the agency websites
and talk to successful grantees about how they
addressed the review criteria.
5. For experimental science proposals (which
most cell biology proposals are), devise
specific aims that can be expressed as
testable hypotheses. Ideally, craft these
hypotheses so that no matter how the study
turns out, something useful will be learned.
Avoid writing vague, open-ended specific
aims that explore your topic in undefined
ways. Remember that you need to convince
reviewers that the money they give you will
be a valuable investment.
Photo credit: Alice Braga
Newbie scientists typically spend most of
their grant-writing time and energy devising
experimental plans that are detailed, well
organized, and interesting. However, although
having a sound and intriguing
research plan is necessary for
getting a grant funded, it is not
sufficient. Consider taking a
more comprehensive approach
to grantsmanship to increase
your probability of success.
Specifically, consider the
following ten rules:
1. Plan to spend months,
not weeks, on your grant
proposal. Assembling a
proposal has many creative
Beth Schachter
and administrative aspects,
and therefore takes a while.
No, you needn’t turn grant-writing into a yearlong, round-the-clock endeavor. But starting
nine months to a year before the deadline, you
should consciously devote some time to your
proposal. Doing so lets you assemble all the
necessary components and players—without
alienating colleagues, mentors, and mentees as
the deadline approaches!
2. Align your proposal with the mission of
the funding agency. Funding agencies have
both long- and short-term missions, and they
must fund work that supports these missions.
If your proposal does not further the mission
of the funding agency, that organization
has no reason to give you money. To learn
about what and whom the agencies are
funding, visit their online databases, most
notably those of the National Institutes
of Health (NIH; http://projectreporter.
nih.gov/reporter.cfm) and the National
Science Foundation (NSF; www.nsf.gov/
awardsearch).
3. Identify and consult the appropriate
program officer for advice on your research
plan early in the process. Program officers
at organizations like NIH are the decisionmakers about what gets funded. They base
these decisions on the recommendations
from the scientific reviewers, along with the
If your proposal
does not further
the mission of the
funding agency,
that organization
has no reason to
give you money.
49
[C]raft ...
hypotheses so that
no matter how the
study turns out,
something useful
will be learned.
50
at least one person in your immediate field
6. Make sure your specific aims are
and at least one colleague from a more
sufficiently independent of each other
distant field, since that is the likely set
that if aim 1 doesn’t work out as planned,
of reviewers you may get at the funding
it doesn’t shut down the rest of your
agency. Try to get critiques from senior
proposed research. The specific aims should
colleagues who have had
inter-relate, preferably to
recent successes at the
address different aspects
funding agency you are
of a single overarching
targeting. Give these
hypothesis. But a negative
[M]any applications
colleagues time to provide
outcome of one aim should
don’t get funded.
critical reviews, and give
not make the other aims
yourself enough time to be
obsolete. Otherwise the
But some do!
able to incorporate their
funding agency could argue
suggestions.
that it doesn’t need to fund
10.If at first you don’t
the entire project.
succeed, try, try again! Funding for
7. Make your text easy to read by using
academic science is limited, which means
clear, simple, persuasive writing with a
that many applications don’t get funded. But
minimum of jargon. Create a document
some do! So, learn from your unsuccessful
that can be read and understood by
attempts by reviewing those applications
tired, cranky reviewers who may read
and the accompanying critiques with senior
the proposal in bits and pieces. Not
colleagues and program officers. Such
all reviewers will be tired, cranky, and
conversations will help you determine ways
frequently interrupted, but allow for the
to improve the quality of your research plan
possibility that one of your reviewers will
and its presentation, setting you on the path
be. Make your proposal easy for that person
to successful grantsmanship. n
to understand and appreciate.
—Beth Schachter, Beth Schachter Consulting and
8. Use graphics to your advantage, not to
Still Point Coaching & Consulting
your detriment. Keep in mind that while
some reviewers will read your proposal onscreen, others will read it as a printout,
Notes
perhaps in color but maybe in black and
This article is based on a workshop sponsored by
white instead. Don’t risk confusing the
the ASCB Minorities Affairs Committee at the
reviewer who reads your proposal as a black- ASCB 50th Annual Meeting, December 2010.
and-white document. Be sure that all the
The author dedicates this article to Liliana
information you intend to convey in your
Ossowski, Professor Emeritus, Mount Sinai
graphics can easily be seen in any of these
School of Medicine, a superb cell biologist
document formats. In addition, be sure that
who also understands grantsmanship and has
graphics that look crisp and well defined on- generously tried to teach those mentees who are
screen retain their sharpness in the printed
capable of listening.
version.
Information about Beth Schachter
9. Make sure that the reviewers are not the
Consulting and Still Point Coaching
first people to read your proposal. Give
& Consulting can be found at www.
yourself time for feedback from colleagues
bethschachterconsulting.com and www.
and mentors. Have your proposal read by
stillpointcoaching.com.
DEAR Labby
Careless Duality by PI Erodes Trust, Endangers
Postdoc’s Career
Dear Labby,
A serious publication issue has arisen for me. It has a copyright aspect,
which is being handled by the publishers, but it also has a bearing on my
relationship with the coauthor (the head of the lab in which I’m a postdoc).
In brief, we were invited by a cell physiology journal to write a review article
on our joint research on mechanisms that determine apical-basal cell
polarity of intestinal epithelium. After review and some revision, it was
published in November 2009.
Last fall, I was talking with a second-year medical student at our
institution who was interested in joining our lab for a research internship this summer. As we chatted,
she told me how much she had enjoyed my “chapter.” I replied that we call these publications
“reviews” (thinking that she had merely used the wrong terminology). What she said next stunned me:
“No—it was in a book.” She told me that she had seen a book in the library with a chapter by me and
my lab head. I immediately went to the library to look at the book, and there was the chapter. What is
more, it was identical, word for word, to the published review article!
Furious, I went to see my lab head. He explained that he was invited to write a chapter for
the book and thought it was OK to use our published review because “the audiences of the two
publications are different.” I asked him how he could do that, even if it could be justified (which I
don’t think it can be), without consulting me, the coauthor. He said that he thought I’d be pleased
to have a chapter in a medical book to complement my research publications. But he added that, in
hindsight, he should have sought my permission. He also said that he had intended to put a footnote
in the proofs of the book chapter, indicating that the chapter was reproduced from the published
review article. (This assumes that the book publisher would have been comfortable with that
altogether.) But he said that when the proofs arrived, he was “very busy and forgot.”
While the dual publication issue is being addressed by the publishers, lab head, and our
institutional officials, I am interested in Labby’s advice for me: How I can make the best of this
unfortunate situation regarding my reputation, career, and relationship with my lab head? That
relationship has been severely tested, and I daresay eroded, by this matter.
—Duped into Duality
Dear Duped into Duality,
This was egregious misbehavior on the part of your lab head. The most immediate issue is to get your
innocence on the record. Presumably the institutional officials handling this matter know that you had
no knowledge of the book chapter being submitted. However, you should confirm that this fact is on
the record, in writing.
Second, depending on what either publisher prints on this (a corrigendum, clarification, etc.),
take all possible steps to ensure that such statements convey your innocence. It is possible that the
journal will take legal action against the publisher of the book or your lab head—the latter’s violation
of copyright may have led to commercial profit. If the journal required transfer of copyright, was the
form signed by both you and your lab head, or only by him on behalf of all authors? If the latter, you
should ask him to give you a copy. In the case of the book, clearly he either signed such a form alone,
or on behalf of all authors. If on behalf of all authors, the legal expectation underlying the form is that
he did so with consent.
What now comes of your relationship with your lab head? A generous interpretation of his action
would be that a very busy lab head forgot to tell a book publisher that a submitted chapter had been
published elsewhere, verbatim. Busy people can forget all sorts of “little things.” But in this case what
your lab head forgot represented an ethical lapse. Presenting a pre-publication journal article as a
new chapter is, in essence, a lie. To be truthful, your lab head should have requested your permission,
obtained the journal and book publishers’ permission (which probably would not have been provided),
and given appropriate attribution. His failure to do this suggests that your lab head may not possess
the “habit of truth,” the central ethos of science. Further, to suppose that he was so busy when the
proofs came that he forgot the footnote of attribution strains belief.
Frankly, Labby feels that based on what you have reported, your lab head cannot be trusted.
One can only speculate on the range of his duplicity in other arenas. You will need to decide if his
contrition is sufficient and the lapse uncommon. Ask yourself whether you can rebuild a reasonable
working relationship. Or has it eroded to a degree that moving on to a different lab is the better
option? In the latter case, you would want to seek counsel from the department chair or other
51
advisers on the completion of your work for publication. This will also ensure that other eyes are
sentinels for possible retaliation, in any form. This is a danger that sometimes lurks in these cases.
Should you decide to stay in the lab and complete your work, you must be alert to signs that the lapse
was more than a one-time error in judgment. n
—Labby
Direct your questions to [email protected]. Authors of questions chosen for publication may indicate
whether or not they wish to be identified. Submissions may be edited for space and style.
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David Christian
Jeffrey Christiansen
Ji Chu
Pei-Yu Chu
Youjun Chu
Sohee Chun
Tae-Hwa Chun
Jarom Chung
Yeoun Ho Chung
Lee Churchman
Nick Cianciola
Nicole Clarke-Medley
Ashley Clayton
Beverly Clendening
Virginia Clowes
Christopher Cockcroft
Paul Coffer
Roy Cohen
Stanley Cohen
Daniel Colacurcio
Monica Colaiacovo
Antonino Colanzi
John Collins
Marta Columbaro
Leslie Conway
Michael Cooper
Catherine Cormier
Ivan Correa
Jason Correnti
Judite Costa
Manoel Costa
Nathanael Cottam
Charisa Cottonham
Aurelie Couesnon
Genevieve Coulombe
Sara Courtneidge
John Crean
Alexandra Cretu
Beverly Crider
James Crish
Monica Croke
Michelle Cronin
Matt Crook
Emily Cross
Elizabeth Crowe
Joy Crowther
Lissette Cruz
Silvia Cruz
Dana Cruz
Bianxiao Cui
Yehia Daaka
Caroline Dalton
Alexxandra D’Angelo
Nikolai Daraselia
Francois Darchen
Abhishek Das
Ranjan Das
Soumita Das
Philip Dash
Ludovic D’Auria
Alexandre David
Jean Davidson
John Davis
Heather Davis
Matthew Davis
Olga Davydenko
Ellen Dawley
Giancarlo De Ferrari
Sam Dean
Chureshma Dean
Mary Dear
Shawon Debnath
Ashley DeCoux
Delphine Delacour
Christophe Delenda
Wulan Deng
Yaanik Desai
Brinda Desai
Carly Desmond
55
Guillaume Desrochers
Michael DeStefano
Paige Dexter
Georgios Dialynas
Marc Diamond
Justin DiAngelo
Juan Diaz
Maria Alejandra Diaz Miranda
Margarete Digel
Ozlem Dilek
Nevena Dimova
Polimyr Caesar Dave Dingal
Raffaella Diotti
Rachael Dippold
Dara Ditsworth
Evgenia Dobrinskikh
Richard Doe
Akiko Doi
Lee Dolat
Viktoria Doll
John Domider
George Dominguez
Anne Donaldson
Sam Donovan
Kirk Donovan
Kathryn Dorst
Stephen Douthwright
Christopher Dowdy
Megan Dreier
Theodore Drivas
Ryan D’Souza
Min Du
Michelle Dubuke
Karen Duca
Pradeep Dudeja
Noelle Dwyer
Sabrina Easington
Seham Ebrahim
Michael Eck
Selina Eckert
Daniele Ejzykowicz
Yael Elbaz
Arye Elfenbein
Natalie Elia
Nadia Elkhatib
Lehman Ellis
Mohammed El-Mezgueldi
Yoshikazu Emi
Diti Emporelli
Martin Engelke
Elias Epp
Timothy Errington
Julian Eskin
Cedric Espenel
Virginia Espina
Jason Evans
Shavonda Evans
Patrick Eves
Christopher Eyermann
Noel Faherty
Corinne Fairchild
Samantha Falk
Dana Fallaize
Tobias Falzone
Yanshan Fang
Reza Farhadifar
Carlita Favero
Tatyana Fedotova
Elizabeth Feeser
Daniel Feliciano
Danielle Feligno
Augustine Felix
Shanshan Feng
Maria Fernandes
Maruska Fernandes
Dawn Fernandez
Ignacio Fernandez-Garcia
56
Fernanda Ferrao
Mark Ferreira
Alexander Feuerborn
Benjamin Field
Jonathan Fillatre
Grigory Filonov
Victoria Findlay
Hayley Finkelstein
Laura Firstenberg
Katherine Fishwick
Amira Fitieh
Mark Fitzgerald
Margaret Fleetwood
Sarah Fletcher
Miguel Flores-Vergara
Patrick Flynn
Kevin Foley
Chii Shyang Fong
Meredyth Forbes
Eva Forgacs
Marisa Fortunato
Deanne Francis
Janusz Franco-Barraza
Evan Frank
Karl Franke
Keith Fraser
Jacqueline Freed
Caroline Freeman
Teryl Frey
Andreas Fritz
Nicholas Frost
Kimberly Fryrear
Xiaoqin Fu
Meng-meng Fu
Wenxiang Fu
Jun Fuchimoto
Tomofumi Fujino
Shunji Fujioka
Yusuke Fukuda
Christopher Fullenkamp
Tomoko Funakoshi
Tatsuyoshi Funasaka
King Leung Fung
Manohar Furtado
Mariana Gadaleta
Andrew Gaffney
Kinisha Gala
Umberto Galderisi
Charlotte Galimow
Kimberly Gallagher
Julia Gallinger
Luciana Gallo
Paul Gambon
Woodrow Gandy
Subhashree Ganesan
Patrick Gannon
Hongai Gao
Lizeng Gao
Nan Gao
Ying Gao
Cecilia Garcia
Isaac Garcia Carrillo
Maria Gracia Garcia Mendoza
David Gau
Jeremie Gautier
Anna Gayek
Jingping Ge
Britta George
J. Peter Gergen
Mathias Gerl
Ramkishore Gernapudi
Gisa Gerold
Dan Gestaut
Erin Gestl
Amanda Gett
Amin Ghabrial
Randeep Ghariyal
Ladan Gheiratmand
Piya Ghose
Paramita Ghosh
Arnaud Giese
Rachel Giles
William Gillis
Miriam Ginzberg
Michael Glista
Paul Gold
Luis Gomez
Elena Goncharova
Patricia Gonzalez-Greciano
Matthew Good
David Gordon
Elizabeth Gorringe
Naoya Gotoh
Monica Gotta
Michael Granato
M’Hamed Grati
Ryan Gray
Brian Graziano
Jennifer Green
Michael Greenberg
Ian Greenstein
Matthew Greseth
Patrick Griffith
Gillian Griffiths
Alexander Groisman
Vincent Groppi
Nikita Gudimchuk
Colleen Guerin
Sonia Guha
Amneet Gulati
Tina Gumienny
Jing Guo
Xiuyang Guo
Anindita Gupta
Aditi Gupta
Serap Gur
Pinar Gurel
Lisa Gurski
Eva Gusnowski
Jose Gutierrez
Kayla Hager
Engda Hagos
Soo-Hyun Hahm
Katharine Hahn
Hana Hall
Mark Hall
Justin Hallgren
Adrian Halme
Stephanie Hamill
Perry Hampilos
Young-Hoon Han
Min Han
Xue Han
Emily Haner
Stephen Hann
Samantha Hanna
Lauren Hansen
Carsten Hansen
Ditte Hansen
Akemi Hara
Heather Harlin
Vance Harper
Melanie Harriff
Tajie Harris
Matthew Hartman
Saori Hata
Laura Hautala
Jonathan Havel
Taviare Hawkins
Tomomi Hayashi
Karen Hayes
Yi He
Li He
Bin He
Thomas Hearn
Andrew Hegle
Brian Heiniger
Nicola Hellen
Bradley Heller
Michelle Helms
Melissa Hendershott
Adam Hendricks
Steven Henry
Clarissa Henry
Jessica Henty
Matias Hepp
Sandy Hernandez
Michelle Hernandez
Heather Herrington
Kevin Hewitt
Amanda Hicks
Antoine Hicks
Janet Hicks
Amy Hicks
Michael Hilinski
Warren Hill
Justin Hines
Karan Hingorani
Laura Hink
David Hipfner
Ashley Hipps
Cheryl Ho
Duane Hoch
Kathryn Hodge
Tyler Hodges
Bernard Hoflack
Brittany Hollister
Tetsuya Hori
Michael Horsey
Michael Horton
Andrew Houk
Amber Howard
Katie Howe
Jen-Chih Hsieh
Chia-Wen Hsu
Matthew Hsu
Pei-Hsin Hsu
Li-Yen Hu
Daniel Hu
Xiaohua Hu
Wei-Pang Huang
Yuejia Huang
Chuan-Hsiang Huang
Hung-Hsiang Huang
Chu-Chun Huang
JoAn Hudson
Chia-Sui Hung
Rupert Hung
Jatta Huotari
Jennifer Hurst-Kennedy
Ali Hussain
Daniel Hwang
Takehiko Ichikawa
Motomasa Ihara
Amy Ikui
Olha Ilnytska
Rieko Imae
Naoyuki Inagaki
Takao Inoue
Roshanak Irannejad
Keith Ireton
Dan Ishihara
Hellen Ishikawa-Ankerhold
Allison Isola
Adrian Israelson
Tamaki Ito
Kentaro Ito
Terri Iwata
Padmanabhan Iyer
Geroge Jackson
Jordan Jacobelli
Eva Jaeger
Anna Jagielska
Shweta Jain
Sean Jamieson
Nageswara Rao Jampani
Anastasija Jancina
Ik Soon Jang
Carsten Janke
Karry Jannie
Silvia Jansen
Heike Janusch
Timothy Jarvela
Fnu Jasmin
Edritz Javelosa
Uma Jayachandran
Bhavani Jayaram
Sujeeve Jeganathan
Edmund Jenkins
Kilhun Jeong
Jae-Eun Jeong
Jihye Jeong
Danny Jeyaraju
Liwei Jia
Da Jia
Chang Jiang
Patricia Jimenez
Jonathan Johnnidis
John Johnson
Alexis Johnson
Duncan Johnstone
Carrie Jolly
Rachel Jones
Gregory Jones
Meredith Jones
Steven Jones
Laura Jones
Carly Jordan
Prakash Joti
Michelle Juarez
Joon-Il Jun
Jin Hyun Jun
Cynthia June
Jung Jung
Jae-Joon Jung
Egle Juskeviciute
Gladys Kaba
Lilian Kabeche
Anil Kumar Kadegowda
Marie-Luise Kaiser
Hideko Kaji
Edward Kalmykov
Yuki Kamada
Jong-Sun Kang
Joshua Kangas
Robert Kao
Nick Kaplinsky
Sonia Kapoor
Gurpreet Kapoor
K. Karnas
Tangavelou Karthikeyan
David Kast
Kosuke Kato
Sandip Kaur
Devinderjit Kaur
Gaurav Kaushik
David Kavanagh
Levent Kaya
Rachael Kells
Kristopher Kennedy
Dai Fei Elmer Ker
Justin Kerr
Stephanie Ketcham
Saleen Khan
Jamal Khan
Nimisha Khanduja
Jayshree Khanikar
Yu Kigoshi
Shingo Kihira
Sungjin Kim
Chaekyun Kim
Dae In Kim
Daehwan Kim
Minhee Kim
Rinho Kim
Hyun Jung Kim
Jae-Ho Kim
Ji-hee Kim
Jin Hee Kim
Youngsoo Kim
Thae Hyun Kim
Leung Kim
Mi-Yeon Kim
Su Kyoung Kim
Mi Jeong Kim
Mi-Ju Kim
Hajime Kimura
Nguyen-Ngoc Kim-Vy
Elizabeth King
Anatoly Kiyatkin
Eric Klein
Sarah Klein
Bertrand Kleizen
Janice Knepper
Charniece Knight
Andreas Knodler
Melodie Knowlton
Chun-Jung Ko
Adam Koch
Demelza Koehn
Hannu Koistinen
Raili Koivuniemi
Yoshitsugu Kojima
Abimbola Kolawole
Alexander Kolb
Nikolai Kolba
Naoki Komatsu
Emilia Komulainen
Tomo Kondo
Chen Kong
Ying Kong
Nozomu Kono
Sunwoo Koo
Mark Kopecky
Sachin Kotak
Dev Kothapalli
Lyudmila Kotlyanskaya
Thomas Koval
Tia Kowal
Anjan Kowluru
Kosuke Koyama
Hiroshi Koyama
Patrycja Kozik
Elisabeth Krainer
Tal Kramer
Lawrence Kramer
Cecilia Krampah
Tracy Kress
James-Paul Kretchy
Sophie Krieger
Harini Krishnan
Konrad Krzewski
Kristopher Kubow
Wolfgang Kuehn
Daniel Kuemmel
Tara Kuipers
S Kuivaniemi
Wanda Kukulski
Wojciech Kulacz
Yuka Kumagai
Suresh Kumar
Pritesh Kumar
Arun Kumar
Jitendra Kumar
Alpana Kumari
Ezgi Kunttas-Tatli
Min-Hao Kuo
Natasza Kurpios
Stephen Kusi
Matthew Kutys
Shu Kwan
Ernie Kwok
Misun Kwon
Chae Hwa Kwon
Su Jung Kwon
Chandrashekara Kythanhalli
Anne-Marie Ladouceur
Tim Laemmermann
Yen Chun Lai
Jonathan Lam
Nathalie Lamarche-Vane
Nayan Lamba
Helena Lamptey
David Lancaster
Susan Lancelle
Stephanie Lange
Karen Lange
Thomas Langer
Gregory Langland
Pamela Langner
Chris Langsdorf
Taotao Lao
Ross Lapenta
Damien Laporte
Ma Guadalupe Lara Cardoso
Heidi Larkin
Jesper Larsen
Keith Latham
Derek Lau
Main Tat Lau
Caitlin Lazar
Mael Le Berre
Luis Lebron
Hyun-Gwan Lee
Pilhwa Lee
Ho-Soo Lee
Kyungwon Lee
Miseon Lee
Sandra Lee
Dooyoung Lee
Siu Sylvia Lee
ChangHwan Lee
Changsu Lee
Donghoon Lee
Ji Sun Lee
Jinmin Lee
Sangkyu Lee
Shin-Ai Lee
Sunkyung Lee
Kangae Lee
Jae Wang Lee
Julia Lee-Soety
Sylvie LeGall
Wesley Legant
Benjamin Lelouvier
Adam Leman
Amanda Lemoncelli
Mei Leng
Ana-Maria Lennon-Dumenil
Martin Leonard
Weng Yee Leong
Satu Leppanen
Violetta Leshchenko
Mette Lethan
Brian Leung
Julio Levano Garcia
Marshall Levesque
Anna Leychenko
Zhaoliang Li
Xiao Li
David Li
Dong Li
Meihua Li
Yeran Li
Deqiang Li
Hua Li
Qiutang Li
Yan Li
Ang Li
Ching-Ju Li
Jieyue Li
Karin Lilja
Evelyne Lima Fernandes
Grace Lin
Shin-Yi Lin
Chiou-Hong Lin
Keng-hui Lin
Pei-Hui Lin
Samantha Lindemann
Rafael Lindoso
Yading Ling
Yih-Cherng Liou
Lydia Little
Shulin Liu
Ting-Ting Liu
Judy Liu
Dongyun Liu
Lynn Liu
Yu-Tsan Liu
Ming Liu
Naiyou Liu
Gang Liu
Jie Liu
Jun Liu
Shuang Liu
Shujing Liu
Zhiyu Liu
Wei Liu
James Liu
April Livengood
Amanda Lloyd
Christian Loch
Andrew Locke
Patricia Lodato
Maura Loew
Christopher Loewen
Alexis Lomakin
Ian London
Kathleen Long
Margaret Long
Jose Lopez
Patricia Lopez
Jane Lopilato
Francesco Lotti
Hezhe Lu
Hsiangmin Lu
Justine Lu
Xuelong Lu
Sharon Lubkin
Helena Lucente
Katarzyna Ludwik
Cecillia Lui
Jennifer Lumb
Annie Albin Lumen
Yi Luo
Guangzuo Luo
Lauren Lusardi
Patrick Lynch
Swetha M.G
Li Ma
Hedia Maamar
Danielle Maatouk
Dawn Macdonald
Stacey MacGrath
Jason MacGurn
James Machamer
Ben Machta
Lindsay Macnamara
Laura Macro
Damian Madan
Suresh Maddur Ganesan
Reo Maeda
Stefano Maffini
Christine Maguire
James Mahaffey
Madhupriya Mahankali
Ahmed Mahmoud
Chelsea Mahoney
Teresa Maia
Lukasz Majewski
Pralay Majumder
Shubhra Majumder
Maria Malagon
Denise Malcolm
Amy Malhowski
John Maloney
Anastasios Mamalis
Aline Mamo
Miyeko Mana
Surya Manandhar
Richard Mangio
Tapan Maniar
Sriram Manivannan
Cara Marie Manlandro
Dipak Manna
Aki Manninen
Abed Mansour
Elaine Manzanilla
Vincent Marchese
Nancy Marcus
Neil Margulis
Stefania Mariggio
Margaret Markiewicz
Leonard Maroun
Lucrecia Marquez-Rosado
Jean-Louis Martiel
Teresa Martin
Lee Martin
Esteban Martinez
Jessica Martinez
Jose Martinez
Rosa Martinez-Garcia
Matthew Martz
Masahiro Maruoka
Laura Mascibroda
Masato Mashimo
Sean Masi
Jeffrey Mason
Vicky Massicotte
Satoko Matsunaga
Jason Matthews
Matthew Maurer
Emma Maxwell
Madelyn May
Viveka Mayya
Liudmila Mazaleuskaya
Javier Mazzaferri
Cheryl Mazzeo
Patrick McCall
Nathanael McCurley
Diane McGarvey
Nunu Mchedlishvili
Andrew McKenzie
Kevin McKenzie
Molly McQuilken
Molly McShea
Derrick McVicker
Jacqueline Meadows
Sadia Mehdi
Haley Melikian
Alicia Menard
Yifat Merbl
Johann Merlin
Claudia Mermelstein
David Merrick
Addias Mervin
Bruno Mesmin
Jeannette Messer
Regis Meyer
Ann Meyer
Rafael Meyer
Rosa Meza-Acevedo
Yansong Miao
Allison Michaelis
Rebecca Michaud
Teije Middelkoop
Kari Midthun
Justin Mih
Tamara Mikeladze-Dvali
Eric Miller
Matthew Miller
Lindsey Miller
Kelly Miller
Brenda Milner
Jianghong Min
Joshua Mincer
Yekaterina Miroshnikova
Hamed Mirzaei-souderjani
Toru Misawa
Stephanie Miserey-Lenkei
Hemlata Mistrry
David Mitchell
Daniel Mitchell
Natalia Mitin
Kazuhiko Mitsumori
Kei Miyakawa
Rui Miyakita
Karolina Mizeracka
Jay Moden
Catherine Mogle
Abhishek Mohanty
Adone Mohd Sarip
Carlos Molina
Dorothee Molle
Sarah Mollerup
Michelle Mondoux
James Monslow
JoAnne Montalbano
Fabio Montico
Ben Montpetit
Peter Moore
Maria Morales
Miguel Moreno-Garcia
Francesca Morgera
Akifumi Morinaka
Makiko Morita
Natalia Moroz
Christina Morra
Robert Morris
Natalia Morsci
Laurel Moses
Oleksandra Moseychuk
Tyler Moss
Armen Moughamian
Susan Movitz
Alexandra Moyzis
Roman Mrozowski
Keeley Mui
Sushmita Mukherjee
Kamalika Mukherjee
Eliane Muller
Eileen Mulrenin
Lise Munsie
Shiefumi Murakami
John Muraski
Deborah Murdock
Laura Murphy
Erin Murphy
Danielle Murphy
Gavin Murphy
Janice Murtagh
Poornima Murthy
Anne Musch
57
Yana Musinova
Gayatri Muthukrishnan
Sivaramakrishnan
Muthuswamy
Jenny Nachbar
Guilherme Nader
Alexis Nagengast
Ramy Naguib Attia
Urja Naik
Gautham Nair
Yuko Nakagawa
Suk Namgoong
Suman Nanda
Nance Nardi
Sonia Navas-Martin
Yael Nechemia-Arbely
Saskia Neher
Christopher Neufeldt
Irene Newton
Mei Ng
Toan Ngo
Phuong Anh Nguyen
Minh Nguyen
Joshua Nicholson
Zilin Nie
Anna Nikonova
Subbaiah Nimmagadda
Padmaja Nipanikar
Mayuko Nishi
Junichi Nishikawa
Emi Nishimura
Marie Nlend
Kristen Noble
John Noel
Kirsten Nole
Benjamin Nordholz
Stephen Norris
Melanie Norstrom
Hanson North
Jennifer Norton
Laura Norwood Toro
Juliana Novaes
Nathaniel Noyes
Marcela Nunez
Molly Nyholm
Patrick Oakes
Yuuki Obata
Michael Oberholzer
Jhon Ochoa Alvarez
Akinleye Odeleye
Erin Odonnell
Shinichi Ogawa
Abigail Ogle
Olalekan Ogundele
Wonjun Oh
Seog Bae Oh
Seung Ja Oh
Masatoshi Ohgushi
Satoshi Okada
Yoshinao Oki
Maria Jesus Olarte
Oluwatunmise Olayinka
Mauricio Olguin
Samantha Olier
Sergio Oliveira
Ruan Oliveira
Olulope Olufemi
Yan Shan Ong
Kay Opperman
Meital Oren-Suissa
Brian ORourke
Jessica Orr
Bernardo Ortega
Ellen OShaughnessy
Ron Osmond
Daniel Osorio
Benjamin Ostendorf
58
Elvira Osuna-Highley
Kaitlin Oswald
Tetsuhisa Otani
Patrick Oton
Nadia Oualha
Madeleine Oudin
Patricia Outeda
Jessica Overstreet
Kristine Anne Pablo
Jon Paczkowski
Laura Palmer
Hung-Wei Pan
Catherine Pan
Alexander Panaccione
Sai Srinivas Panapakkam
Giridharan
Tatyana Panchenko
Lisa Pang
Marie-Christine Paquin
Ranjani Paradise
Stephane Parent
Janel Pariseau
Geunyeong Park
Jeehae Park
Eunchan Park
Kyu-Sang Park
Jaeyoung Park
Jonathan Park
Hye Yoon Park
Junsoo Park
Tae-Ju Park
Deric Park
Hollie Parker
Nitika Parmar
Tari Parmely
Amy Parsons-White
Raghuveer Parthasarathy
Pete Pascuzzi
Raymond Pasek
Lejla Pasic
Alison Pass
Jose Pastor-Pareja
Kirishma Patel
Falshruti Patel
Cassandra Patenaude
Kelvin Pau
Savvas Pavlides
Carlos P-Descovich
Deepa Pednekar
Olga Pekar
Christine Peladeau
Claudia Pellacani
George Pellegrino
Sara Pereira
Kayla Perez
Andres Perez Bay
Gabriela Perez-Alvarado
Deforest Peterson
Douglas Peterson
Alexandra Pettit
Kathleen Pfaff
William Pfund
Jennifer Phelan
Denis Phichith
Julia Philip
Greg Phillips
Jacqueline Pierce
Pascal Pigny
Nicolas Piguel
Amanda Pike
Mary Pinter
Joerg Piontek
Michelle Pirruccello
Aaron Pitre
Thomas Planchon
Jennifer Plank
Laure Plantard
Michael Podolsky
Paolo Poggio
Francoise Poirier
Michael Polen
Celia Pombo
David Porbunderwala
Joshua Porter
Caelin Potts
Natalie Poulter
Indira Prabakaran
Arun Pradhan
Mariano Prado Acosta
Masha Prager-Khoutorsky
Herman Prakasam
Christine Priano
Regan Price
Jeanette Prieston
Eloise Prieto
Veronique Proux-Gillardeaux
Michael Prummer
Javier Puente
Heather Pursel
Sofia Pustlnik
Serapion Pyrpassopoulos
Minhua Qiu
Feng Qiu
Hong Qu
William Querbes
Manuela Quintavalle
Omar Qureshi
Wajeeha Qureshi
Alexander Rabovsky
Robert Radford
Sarah Radford
Hamidah Raduwan
Ilona Rafalska-Metcalf
Arjun Raj
Ileng Ramachandran
Sitharam Ramaswami
Angelika Rambold
Aarti Ramdaney
Laura Ramsay
Sripriya Ranganathan
Kasturi Ranganna
Devulapalli Rao
Mikhail Rassokhin
Raphael Rastetter
Gayatri Rath
Prabakaran Ravichandran
Poulomi Ray
Rachel Raynes
Dikla Raz Ben Aroush
Kavya Reddy
David Reeder
Natalia Reglero-Real
Elizabeth Rego
Erin Remaly
Fioranna Renda
Jayanthi Repalli
Shoval Resnick
Anne-Cecile Reymann
Ashley Reynolds
Annie Reza
Daniele Ribeiro
Jun Rice
Jean-Philippe Richard
Darren Richard
Jillian Richter
Leah Rider
Ugo Ripamonti
Saajidha Rizvydeen
Brooke Roberts
Nathan Roberts
David Roberts
Christian Rocheleau
Amanda Rocklyn
Monica Rodriguez Silva
Anja Roeder
Krzysztof Rogowski
Jennifer Rohn
Stephane Rolland
Erik Ronzone
Brian Rooney
Bernhard Roppenser
Wesley Rose
Joshua Rosenberg
Mitchell Ross
Ninna Rossen
Nikki Rossetti
Chantal Roubinet
Muriel Roulet
Robert Rowlands
Ariadna Yolanda Ruiz-Loredo
Gordon Rule
Gillian Ryan
Elizabeth Ryder
Akihide Ryo
Dora Sabino
Alexander Sabre
Pablo Saez
Rachaan Sainger
Yuhki Saito
Yuki Sakaguchi
Tsuyoshi Sakai
Kenjiro Sakaki
Maria Sakkou
Yasuhiro Sako
Mika Sakurai
Norbert Deepa Salagala
Danielle Salantes
Joseph Salem
Jeremy Salerno
Keyan Salimian
Margaret Sallah
Yasaswini Sampathkumar
Keri Sanborn
Eugenio Sanchez-Moran
Leanne Sandieson
Poonam Sansanwal
Bridgett Santos
Mark Santos
Balazs Sarkadi
Reiko Sato
Takashi Sato
Mizuho Sato
Karsten Sauer
Randi Saunders
William Savigne
James Sbarboro
Christine Scaduto
Angela Schafer
Andreas Schaupp
Eyal Schejter
John Schiel
Zachary Schilling
Christina Schindler
Karen Schindler
Barbara Schlingmann
Kimberly Schneider
Victoria Schoepke
Heather Schofield
Laura Schramm
Jennifer Schrandt
Monica Schueller
Dianne Schwarz
Thomas Schwarz
Maria Seabra
Neeraj Sebastian
Stefano Sechi
Marisa Segal
Nikolina Sekulic
Madhavi Senagolage
Yosuke Senju
Sharon Sequeira
Barbara Seredick
Gramille Serrano
Christina Servas
Florian Settele
Maxwell Shafer
Niyant Shah
Nassim Shahrzad
Stephen Shang
Hua Shao
Suresh Sharma
Leilani Sharpe
Shankar Shastry
Alex Sheftel
Muyao Shen
Dongbiao Shen
Zhen Shen
Shailesh Shenoy
Blythe Shepard
Qian Shi
Dai Shiba
Shinyi Shieh
Hsiu-Ming Shih
Hyunjin Shin
Norihisa Shindo
Tatsushi Shintaku
Maki Shiono
Hamasseh Shirvani
Ihori Shitanda
Archana Siddam
Marion Siegman
Dirk Siepe
Jorge Sierra-Fonseca
Kristen Sigley
Frederic Sigoillot
David Silva
Serena Silva
Antonia Silva
Deborah Silverman
Fernando Simabuco
Sergio Simoes
Bart Simon
Derek Simon
Jeffrey Simons
Vimla Singh
Joo-Hee Sir
Albert Siryaporn
Andrea Slade
Christopher Slagle
Joshua Slee
Danielle Sliter
David Slochower
Holly Smith
Tara Smith
Brandon Smith
William Smith
Jessica Soe
Andreas Solomos
Sungmin Son
Esther Son
Yanjun Song
Rajesh Soni
Madhav Soowamber
Vincent Soubannier
Philip Spear
Susan Spence
Katrina Spencer
Mirela Spillane
Nadja Spitzer
Andrew Spracklen
Martin Srayko
Vasudha Srivastava
Pallavi Srivastava
Jaya Srivastava
Megan Stackpole
Jennifer Stanford
Ethel Stanley
Michelle Starz-Gaiano
Lindsey Stavola
Julian Steinwachs
Madison Stellfox
Andrew Stephens
Dominique Sterling-Wells
David Sterner
Douglas Stevenson
Jeffry Stock
Katherine Stockstill
Emily Stoops
Kirk Stovall
Mary Strasberg De Rieber
Devin Strickland
Karl-Heinz Strucksberg
Scott Stuart
Emma Sturgill
Cristian Suarez
Maria Suarez-Sanchez
Fedor Subach
Oksana Subach
Chintha Subasinghe
Vanitha Subbaiah
Radhika Subramanian
Gerald Sufrin
Mary Ann Suico
Jessica Sullivan-Brown
Yuxiang Sun
Mingxuan Sun
Sam Sun
Yi Sun
Yuan-Ting Sun
Sriramkumar Sundaramoorthy
Mahipal Suraneni
Guruprasada Sure
Robyn Sussman
Shingo Suzuki
Aussie Suzuki
Nobuharu Suzuki
Sowmya Swaminathan
Eric Swanson
Kayla Sween
Salahuddin Syed
Ismail Syed
Viktoriya Syrovatkina
Katherine Szarama
Emmanuel Tadjuidje
Denisse Tafur
Laura Taggart-Murphy
Yuling Tai
Constantin Takacs
Yoshiharu Takayama
Peter Takvorian
Junichi Tanase
Soichi Tanda
Jun Tang
Michelle Tang
Tammy Tang
Yangzhong Tang
Selcuk Tanik
Barbara Tanos
Wensi Tao
Juan Tao
Katsiaryna Tarbashevich
Alexandra Tavares
Marcus Taylor
Jonathan Taylor
Ivo Telley
Regina Teo
Kazuo Terashima
Rebecca Tetteh
Desiree Thayer
Manuel Thery
Eric Theveneau
Sarah Thibault
Guillaume Thibault
Christopher Thom
Todd Thoresen
Stephanie Thurmond
Tristan Thwaites
Ruiyang Tian
Jerry Tien
Ajit Tiwari
Abhilasha Tiwari
Andoria Tjondrokoesoemo
Benjamin Toboh
Yudai Tokumasu
Tina Tootle
Laszlo Tora
Keiko Torii
Robert Tower
Erin Tranfield
Mirko Travaglia
Aleksandr Treyer
Vidisha Tripathi
Richa Tripathi
Jeff Tsai
Qingzong Tseng
Koji Tsutsumi
Li-Chun Tu
Philippa Tucker
May Tun
Belma Turan
Zeynep Turan
Kamala Tyagarajan
Yao-Wei Tzeng
Kankanam Gamage Udayanga
Catherine Ueckert
Arisa Uemura
Valerie Ulm
Neil Umbreit
Alok Upadhyay
Christopher Utter
Helene Vacher
Arun Vaidyanath
Julie Valdes
Maria Valenzuela
Dharini Van Der Hoeven
Babet Van Der Vaart
Mark Van Dyke
Roy Van Heesbeen
Anne Van Oosten
Myrrhe Van Spronsen
Abigail Vander Heyden
Natalie Vandeven
Gianluca Varetti
Pablo Vargas
Daysi Vargas Gonzalez
Rafael Vazquez-Martinez
Francisco Velez
Rossella Venditti
William Veon
Werner Verbakel
Marie Versaevel
Anna Veshnyakova
David Vetvicka
Linda Vi
Michelle Villasmil
Michelle Visser
Vignesh Viswanathan
Michael Vogel
Stephen Von Stetina
Anna Vorobyeva
Marija Vukajlovic
David Waddell
Kylie Wagstaff
Jennifer Waldo
Andre Walther
Yihan Wan
Xiaobo Wang
Chenguang Wang
Cheng Wang
Qiao Wang
Yu-Hsiu Wang
Dongmei Wang
Enxiu Wang
Jianyang Wang
Junxia Wang
Chao Wang
Kexi Wang
Minshi Wang
Tien-Cheng Wang
Wenqing Wang
Jack Wang
Shiwei Wang
Fei Wang
Ke Wang
Ting Wang
Xiangchun Wang
Xiaodong Wang
Kenneth Wannemacher
Caitlin Ward
Sonisha Warren
Sunita Warrier
Sadanori Watanabe
Alanna Watson
Jessica Wayt
Frances Weaver
Randy Wei
John Weisel
Kara Welch
Marco Wendel
Kerstin Wendt
Yaochung Weng
Uwe Werling
John Werner
Michael Wheelock
Kelly Whelan
Brad White
Erin White
Richard White
Michael White VanGompel
Eliza Wiech
Winfried Wiegraebe
Christiane Wiesner
Michael Wigerius
Christina Wilcox
Jill Wildonger
Ronit Wilk
Erich Wilkerson
Carly Willenborg
David Willhite
Elizabeth Williams
Kathryn Williams
John Williams
Kaylyn Williamson
Melissa Wilson
Jill Wilson
Meredith Wilson
Christine Wilson
Michael Wilson
Alisha Windhausen
Michelle Wittwer
Jason Wojcechowskyj
Horst Wolff
Kangmee Woo
Will Wood
Liliana Wroblewska
Jianrong Wu
Min Wu
Chia-Ching Wu
Chang-Chih Wu
Jun Wu
Yu Wu
Chi-Fang Wu
Xiaoxuan Wu
Xuewei Wu
Lin Wu
Yizhou Wu
Jun Xi
Peng Xia
Hongai Xia
Meng Xiang
Pingjie Xiao
Sai Xiao Rei
Hanqing Xie
Huajiang Xiong
Hua Xu
Lili Xu
Ming Xu
Smita Yadav
Shunsuke Yagi
Nir Yakoby
Nazumi Alice Yamada
Hiroshi Yamaguchi
Ryosuke Yamamoto
Atsushi Yamamoto
Qi Yan
Dong Yan
Nariaki Yanagawa
Liang-Tung Yang
Shenghong Yang
Chun Yang
Hee Won Yang
Yong Ryoul Yang
Chih-Sheng Yang
Jie Yang
Lin Yang
Christopher Yanucil
Xuanli Yao
Phil Yao
Sharmin Yaqin
Syed Yasir Ahmed
Richard Yau
Mustafa Yazicioglu
Jonathan Ye
Pei-Chi Yeh
Chandra Yelleswarapu
Ling-Huei Yih
Xiling Yin
Ai Kia Yip
Norihiko Yokoi
Soonmoon Yoo
Sa Kan Yoo
Young-Suk Yoo
Yohei Yoshihama
Engy Yossef
Evelin Young
Sarah Young
Amber Yount
I-Mei Yu
Yiyi Yu
Eun-Jeong Yu
Ka Lou Yu
Anan Yu
Ke Yuan
Kun Yuan
Peng Yue
Hiroko Yukinaga
Hesham Zakaria
Juan Zalvide
Dimitrios Zampatis
Horacio Zamudio-Meza
Jennifer Zanet
Ana Zarubica
Anatoly Zaytsev
Justyna Zdrojewska
Adam Zeiger
Scott Zeitlin
Shannin Zevian
Yi Zhan
Dongwei Zhang
Mingjie Zhang
Jie Zhang
Xiang Zhang
Yorke Zhang
Li Feng Zhang
Yanling Zhang
Chunyang Zhang
Donglei Zhang
Man Zhang
Sihui Zhang
Mike Zhang
Jing Zhang
Li Zhang
Na Zhao
Yanmei Zhao
Chunlei Zheng
Guolei Zhou
Chun Zhou
Yixuan Zhou
Xiaorong Zhou
Min Zhu
Hua Zhu
Karen Zhu
Huihui Zhu
Samira Ziaei
Alexandra Zidovska
Melissa Ziegler
Kelaine Zimmerman
Dennis Zimmermann
Yimin Zou
Xin Zou
Matthew Zuber
Thomas Zwaka
Adam Zwolak
Eliza Zylkiewicz
Jacob Zyskind
Members Granted
Emeritus Status
Michael A. Beaven
Richard W. Burry
Coralie A.C. Carraway
Don Cave
Joyce Diwan
Alfred G. Gilman
Dorothy M. Morre
William Okulicz
59
GRANTS & OPPORTUNITIES
Items shown in blue have been added or updated since the last issue of the
Newsletter.
ASCB Minorities Affairs Committee Visiting Professorship Awards and Linkage Fellows Program. See page 38.
High-Throughput-Enabled Structural Biology Research (U01). The National Institute of General Medical Sciences
(NIGMS) encourages applications to establish partnerships between researchers interested in a biological problem
of significant scope and researchers providing high-throughput structure determination capabilities through the
NIGMS PSI:Biology network. Applicants should propose work to solve a substantial biological problem for which the
determination of many protein structures is necessary. Expiration: September 8, 2013.
http://grants.nih.gov/grants/guide/pa-files/PAR-10-214.html.
Mentored Quantitative Research Development Award (K25). The purpose of these National Institutes of Health
(NIH) awards is to attract to NIH-relevant research those investigators whose quantitative science and engineering
research has thus far not been focused primarily on questions of health and disease. Expiration: January 8, 2012.
http://grants.nih.gov/grants/guide/pa-files/PA-09-039.html.
Minority Access to Research Careers Undergraduate Student Training in Academic Research National
Research Service Award Institutional Research Training Grant (T34). The National Institute of General Medical
Sciences will award these grants to eligible institutions as a means of supporting undergraduate academic and
research training for students underrepresented in the biomedical and behavioral sciences. Applications due: May 25,
2011, and 2012. http://grants.nih.gov/grants/guide/pa-files/PAR-10-119.html.
The National Academies’ Research Associateship Programs administer postdoctoral (within five years of the
doctorate) and senior (normally five years or more beyond the doctorate) research awards sponsored by federal
laboratories at over 100 locations in the U.S. and overseas. Quarterly application deadlines.
www7.nationalacademies.org/rap.
National Centers for Biomedical Computing (R01). This funding opportunity is for projects from individual
investigators or small groups to collaborate with the National Institutes of Health Roadmap for Medical Research
National Centers for Biomedical Computing (NCBCs). Collaborating projects are intended to engage researchers in
building an excellent biomedical computing environment, using the computational tools and biological and behavioral
application drivers of the funded NCBCs as foundation stones. Expiration: September 8, 2011.
National Centers for Systems Biology (P50). The National Institute of General Medical Sciences invites grant
applications from institutions/organizations proposing to establish Centers of Excellence in Systems Biology. Letters of
intent due: September 28, 2011. Applications due: October 27, 2011.
Pathway to Independence Award. The primary purpose of the National Institutes of Health (NIH) Pathway to
Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented NIHsupported independent investigators. The program is designed to facilitate a timely transition from a mentored
postdoctoral research position to a stable independent research position with independent NIH or other independent
research support at an earlier stage than is currently the norm. Expiration: January 8, 2012.
Research Supplements to Promote Diversity in Health-related Research. The National Institutes of Health (NIH)
and the Centers for Disease Control and Prevention have announced to PIs holding specific types of NIH research
grants that funds are available for administrative supplements to improve the diversity of the research workforce by
supporting and recruiting students, postdoctoral researchers, and eligible investigators from groups that have been
shown to be underrepresented. Expiration: September 30, 2011.
Research Supplements to Promote Re-entry into Biomedical and Behavioral Research Careers. These
supplements are intended to encourage individuals to re-enter research careers within the missions of all National
Institutes of Health (NIH) program areas. This program will provide administrative supplements to existing NIH research
grants to support full-time or part-time research by individuals in a program geared to bring their existing research skills
and knowledge up-to-date. Expiration: September 30, 2011.
60
GRANTS & OPPORTUNITIES
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in PharmD/PhD
Programs. The objective of this National Institutes of Health funding opportunity announcement is to help ensure that
highly trained PharmD/PhD graduates will be available in adequate numbers and in appropriate research areas to carry
out the U.S. biomedical, behavioral, and clinical research agenda. Expiration: January 8, 2012.
SHIFT Awards: Small Businesses Helping Investigators to Fuel the Translation of Scientific Discoveries (SBIR:
R43/R44). These National Institutes of Health awards are intended to foster research that is translational in nature and
to transform academic scientific discoveries into commercial products and services. They require that an investigator
who is primarily employed by a U.S. research institution at the time of application transition to a small business
concern (SBC) and be primarily employed (more than 50% time) by the SBC by or at the time of the award. Expiration:
January 8, 2013. http://grants.nih.gov/grants/guide/pa-files/PA-10-122.html#SectionIV3A.
Structural Biology of Membrane Proteins (R01). This National Institutes of Health funding opportunity is for
research that will lead to the determination of membrane protein structures at high resolution. In addition to the
structures of integral membrane proteins, the structures of the complexes formed between these proteins and their
biological partners are of interest. Expiration: September 8, 2013.
Supplements for Functional Studies Based on High-resolution Structures Obtained in the Protein Structure
Initiative.
The National
Institute
of General
Medical1/2pg
Sciences
(NIGMS)
announces
ASCB
"Pipette
like
a PRO"
BW
accu-jet
prothe availability
2011 of administrative
supplements to provide funds to enable investigators interested in protein function to capitalize on the information
and material products of the Protein Structure Initiative (PSI). These supplements are available for 1) NIGMS-funded
research grants (R01, R37, and P01) as well as 2) investigators with peer-reviewed research grants not funded by
NIGMS, through the PSI research centers. www.nigms.nih.gov/initiatives/PSI/supplements.
Support of NIGMS Program Project Grants (P01). The National Institute of General Medical Sciences encourages
innovative, interactive program project grant applications from institutions/organizations that propose to conduct
research that aims to solve a significant biological problem through a collaborative approach involving outstanding
scientists who might not otherwise collaborate. Expiration: September 8, 2013.
http://grants.nih.gov/grants/guide/pa-files/PAR-10-266.html. n
“ASCB,” “The American Society for Cell Biology,” “iBioSeminars,” and “Molecular Biology of the Cell” are registered
trademarks of The American Society for Cell Biology. “The Cell: An Image Library” is a common law trademark of The
American Society for Cell Biology.
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61
Photo: David Powers
MEMBERS in the News Did You Know...?
Susan
Lindquist
Stanley
Prusiner
Susan Lindquist of the Massachusetts
Institute of Technology, an ASCB member
since 1983, and Stanley Prusiner
of the University of California, San
Francisco, an ASCB member since
1976, were recipients of the National
Medal of Science, the highest technical
and scientific award given by the U.S.
government.
Steve Caplan of the University of Nebraska Medical Center
in Omaha, an ASCB member since 1990, has published
his first novel, Matter Over Mind, a realistic portrait of
a biomedical researcher struggling with grant troubles,
eccentric lab members, and troublesome colleagues, while
personal problems pile up. Go to www.stevecaplan.net for
details.
Photo: Graham Burkart
Three ASCB members were among
the 85 recipients of the 2010
Presidential Early Career Awards for
Scientists and Engineers:
Magdalena Bezanilla
Joshua Shaevitz
University of Massachusetts,
Amherst
Member since 1997
Princeton University
Member since 2006
Amy Wagers
Joslin Diabetes Center
Member since 2006
In Memoriam
We note the recent passing of ASCB emeritus member Shirley
A. McCormack, and express our condolences to her family,
friends, and colleagues. n
n
n
n
March 31 is the deadline for nominations for seven ASCB
awards—all of which will be presented at the 2011 ASCB
Annual Meeting in Denver, CO, December 3–7.
For information on eligibility and nomination
requirements, see “Call for Nominations” on p. 43 or go
to www.ascb.org and click on “Awards/Grants.”
Please take the time to nominate a deserving colleague,
postdoc, mentor, or student. n
MEETINGS Calendar
A complete list of upcoming meetings can be found at http://
ascb.org/othermeetings.psp. The following meetings were added
since the last issue of the Newsletter:
May 16–17, 2011. Bethesda, MD
The National Heart, Lung, and Blood Institute 2011 Mitochondrial Biology
Symposium: Advances in Mitochondrial Dynamics and Mitochondrialcytosolic Communications. www.NHLBIMitochondrialSymposia.org
May 23–25 2011. Washington, DC
Focus on Reaching Women for Academics, Research, and Development
(FORWARD) to Professorship Workshop.
http://student.seas.gwu.edu/~forward/advance
June 5–10, 2011. New London, NH
Gordon Conference: Tissue Repair & Regeneration.
www.grc.org/programs.aspx?year=2011&program=tissuerep
June 15–18, 2011. Toronto, Canada
International Society for Stem Cell Research 9th Annual Meeting.
www.isscr.org/meetings
July 13–15, 2011. Cambridge, UK
Biochemical Society Focused Meeting: Nuclear Envelope Disease and
Chromatin Organization.
www.biochemistry.org/MeetingNo/SA125/view/Conference
ASCB Annual Meetings
December 3–7, 2011. Denver
December 15–19, 2012. San Francisco
December 14–18, 2013. New Orleans
December 6–10, 2014. Philadelphia
The ASCB wishes to express deep
appreciation to all the exhibitors who
attended the 2010 Annual Meeting
and helped ensure its success.
62
December 12–16, 2015. San Diego
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