School of Nursing Sciences

UNIVERSITY OF NAIROBI
SCHOOL OF NURSING SCIENCES
RESEARCH TOPIC:
FOCTORS AFFECTING ACCEPTABILITY
TREATMENT OF TUBERCULOSIS
TO THE CHEMOTHERAPY
IN INMATES AGED BETWEEN 18-55 YEARS
IN LANG'ATA WOMEN'S PRISON
A RESEARCH PROPOSAL PRESENTED IN PARTIAL FULFILMENT FOR THE
AWARD OF A DEGREE IN BACHELOR OF SCIENCE IN NURSING [BScN] OF
UNIVERSITY OF NAIROBI.
BY:
MURANGO E. MIRITI
H3212630103
BSCN. IV.
SUPERVISOR:
MRSCHEGE,
LECTURER, SCHOOL OF NURSING SCIENCES,
COLLEGE OF HEALTH SCIENCES,
UNIVERSITY OF NAIROBI.
DATE: 2/09/2007
TABLE OF CONTENTS:
Table of contents. . . ... . .. .. . ... . . . ... .. . .. . . . . ... ... ... ... ... ... ... ... ... ... . . ...
Acknowledgement--------------------------------------------------------------Dedication-----------------------------------------------------------------------Declaration----------------------------------------------------------------------Certificate of approval---------------------------------------------------------List of abbreviations-----------------------------------------------------------Operational definitions -------------------------------------------------------Abstract-------------------------------------------------------------------------CHAPTER ONE:
1.0 Introduction----------------------------------------------------------------1.1 Problem statement---------------------------------------------------------1.2 Justification of the study-------------------------------------------------1.3 Research questions-------------------------------------------------------1.4 Main study objectives----------------------------------------------------1.5 Specific study objectives------------------------------------------------1.6 Hypotheses-----------------------------------------------------------------CHAPTER TWO:
LIT~RATlJ~
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---------------------------------------------------CHAPTER THREE
RESEARCH METHODOLOGY: -------------------------------------------2.0 Study design----------------------------------------------------------------3.1 Study area-------------------------------------------------------------------3.2 Study population-----------------------------------------------------------3.3 Inclusion criteria-----------------------------------------------------------3.4 Exclusion criteria----------------------------------------------------------3.5 Sampling method----------------------------------------------------------3.6 Sample size determination-----------------------------------------------3.7 Study instruments---------------------------------------------------------3.8 Pretesting of study instruments------------------------------------------3.9 Data collection-------------------------------------------------------------3.10 Data cleaning ------------------------------------------------------------3.11 Data analysis-------------------------------------------------------------3.12 Data presentation--------------------------------------------------------3.13 Ethical considerations---------------------------------------------------3.14 Control of biases--------------------------------------------------------3.15 Limitation of study------------------------------------------------------3.16 Benefits of the study----------------------------------------------------References
---------------------------------------------------------------APPENDIX;
3.0 Map of study area -----------------------------------------------------3.1 Questionnaire---------------------------------------------------
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3.2 Focus group discussion with wardens------------------
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3.3 ~ ork plan-------------------------------------------------------3.4 Budget-----------------------------------------------------------3.5 Map of Lang'ata-------------------------------------------------3.6 Research participant consent form---------------------------4.6Letter seeking authority to conduct research. -----------------
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ACKNOLEDGEMENT
I acknowledge my supervisor, Mrs. Chege for being so instrumental and
facilitative in the development of this research proposal. I also acknowledge Mr.
Ademba for assistance in getting relevant literature review from the University of
Nairobi Medical School Library. Moreover, classmates and friends for their
continuous psychological support and encouragement during my research work.
III
DEDICATION
I humbly dedicate this research proposal to my beloved family and especially to
my dear parents, Mr. and Mrs. Murango.
IV
DECLARATION
I, Murango E. Miriti hereby declare that the research proposal is my original work
and has not been presented for any award of degree or diploma in any university
before.
Signature ...
a:
Date.&J!iJ.1!.~~
Murango E. Miriti
H321263 0/03
v
ABREVIATIONS:
AIDS -
Acquired Immune Deficiency Syndrome
BScN -
Bachelor of Science in Nursing
CDC
Centers for Disease Control
-
CI
Confidence Interval
HIS
Health Information System
HIV
Human Immunodeficiency Virus
ICRC -
International Committee of the Red Cross
Ksh
Kenya shilling
MDR
-
Multiple Drug Resistant
PTB
Pulmonary Tuberculosis
S.P.S.S.-
Statistical Program for Social Sciences
TB
tuberculosis
U.o.N-
University of Nairobi
WHO-
World Health Organization
Vll
ABSTRACT
Tuberculosis is the leading infectious cause of morbidity and mortality in adult
worldwide, killing about 2 million people every year (22). About 1.6billion are infected
worldwide. Investigation has revealed that there is multiple drug resistant tuberculosis
(MDR-TB) among inmates in Kenya (16). This has been associated with various factors
including low acceptability to TB chemotherapy. This poses big threat to the society in
general as TB continuous to spread to healthy persons and society in general there is need
to look for lasting solution. Currently there is inadequate data and information of factors
affecting acceptability to TB chemotherapy and emergence ofMDR-TB
hence this
research.
This study is a cross sectional study aimed at determining factors affecting
acceptability of chemotherapy treatment of tuberculosis in inmates aged betwwen 1855years in Lang'ata women's prison. The available literature shows that TB is an
important health problem in prison setting (1). This has been associated with poor general
health conditions in prisons, congestion, delayed case finding and poor compliance to TB
chemotherapy.
This study will be conducted using structured questionnaire and focused group
discussion. Trained research assistants will be used. Pretesting of tools will be done in
Kamiti maximum prison. Data will be analyzed using statistical programme for social
sciences (S.P.S.S) computer package. Data will be presented in form of frequency tables,
graphs, and percentages. Findings of the study will be used in making health policies in
prison and improving health for all inmates in Kenya.