Documento generale riassuntivo del XXIX ciclo

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Documento generale riassuntivo del XXIX ciclo
Anagrafe dei dottorati -­‐ a.a. 2013/2014 Le seguenti informazioni devono essere inserite per tutti i corsi attivati dall’a.a. 2013/14, indipendentemente dal ciclo avviato in tale anno. 1. Informazioni generali Corso di dottorato Denominazione del corso Presenza di eventuali curricula (SI/NO) Anno Ciclo Il corso è: nuova istituzione; trasformazione da (selezione da anagrafe 2012) Data del bando Data presunta di inizio del corso Durata prevista Dipartimento proponente Dottorato in collaborazione con le imprese/dottorato industriale (art. 11 del regolamento) (SI/NO) Il corso fa parte di una Scuola di Dottorato? (SI/NO) Se SI quale: Ambito Settori scientifico disciplinari interessati Macrosettore concorsuale BIO/14 Biotecnologie SI 2013-­‐2014 XXIX Nuova istituzione 01.12.2013 36 mesi Chimica, Biologia e Biotecnologie SI NO Aree CUN Interessate Indicare il peso percentuale di ciascuna area 05/G1 05 05: 40 % BIO/10 05/E1 05 06: 30% BIO/11 05/E2 05 03: 20% BIO/09 05/D1 05 02: 5% BIO/18 05/I1 05 07: 5% BIO/19 05/I1 05 BIO/04 05/A2 05 BIO/12 05/E1 05 BIO/15 05/G1 05 BIO/07 05/C1 05 BIO/05 05/B1 05 CHIM/02 03/A2 03 CHIM/06 03/C1 03 CHIM/10 03/D1 03 1 FIS/01 02/A1 02 FIS/03 02/B1 02 MED/09 06/B1 06 MED/18 06/C1 06 MED/04 06/A2 06 MED/16 06/D3 06 MED/42 06/M1 06 MED/50 06/N1 06 MED/40 06/H1 06 AGR/16 07/F2 07 AGR/13 07/E1 07 2 Tipo di organizzazione 1) Singola università SI 2) a. Consorzio Denominazione consorzio Estremi dell’atto di costituzione Consorzio con: NO università italiane NO NO NO università straniere enti di ricerca pubblici o privati di alta qualificazione, anche di Paesi diversi imprese che svolgono attività di ricerca e sviluppo NO 2) b. Convenzione Data di sottoscrizione convenzione Durata convenzione NO Convenzione con: università italiane NO NO NO università straniere enti di ricerca pubblici o privati di alta qualificazione, anche di Paesi diversi imprese che svolgono attività di ricerca e sviluppo NO Atenei italiani consorziati/convenzionati Denominazi Diparti Sede Sede di attività N° di borse one mento amministrativa, formative (SI/NO) finanziate Consorziato/Con
venzionato Rilascio del titolo congiunto/multiplo: (SI/NO) 3 Atenei stranieri consorziati/convenzionati Denominazi Paese Dipartiment Consorziato/Con Sede di N° di borse one o/Struttura venzionato attività finanziate formative (SI/NO) Rilascio del titolo congiunto/multiplo: (SI/NO) Altri Enti consorziati/convenzionati Denominazione Tipologia del soggetto Selezione tra le seguenti opzioni: ente di ricerca, impresa che svolge attività di ricerca e sviluppo Pubblico/Privat Consorziato Paese o /Convenzio
nato Sede di N° di borse attività finanziate formative (SI/NO) Obiettivi formativi (max 1500 caratteri) Il corso è interdipartimentale (Nuovi Dipartimenti: Chimica, Biologia e Biotecnologie; Medicina; Scienze Farmaceutiche; Scienze Chirurgiche e Biomediche, Ingegneria Civile e Ambientale; Fisica e Geologia; Medicina Sperimentale; CEMIN). Il Dipartimento di riferimento attualmente è quello di Chimica. Il programma è organizzato in quattro curricula: Biot. Mediche, Biot. Molecolari e Cellulari, Biomateriali e Biodispositivi, Biot. Industriali. Sono previsti 21 CFU di corsi e seminari suddivisi nei 3 anni. I percorsi formativi sono costituiti da corsi/seminari tenuti da docenti universitari e/o prof. a contratto esperti del settore provenienti dal settore pubblico e privato. Altre attività formative comprendono: tirocini presso laboratori e aziende leader nei settori delle biotec.; corsi di lingua Inglese, di informatica, organizzazione della ricerca e della valorizzazione dei risultati conseguiti; relazioni periodiche sullo stato di avanzamento delle ricerche e stesura dell’elaborato finale. L’attività di ogni dottorando si svolgerà sotto la guida di uno/due tutori individuati dal Collegio dei Docenti. E’ prevista un periodo di stage di almeno 6 mesi presso Istituzioni Estere di livello universitario. Per accedere all’anno successivo, lo studente dovrà superare un esame secondo il regolamento vigente. E’ prevista la possibilità di conseguire il riconoscimento del titolo di Dottorato Europeo e 4 sono in corso le pratiche per il riconoscimento del titolo di Dottorato Internazionale. Sbocchi occupazionali e professionali previsti (max 1500 caratteri) Scopo del dottorando è quello di sviluppare capacità di tipo progettuali, sperimentali e analitiche fino al raggiungimento di autonomia di ricerca e gestione di progetti. In questo modo si consentirà: 1-­‐ Allocazione nel campo della ricerca (università ed altri istituti di ricerca pubblici e privati); 2-­‐ Allocazione nelle industrie biotecnologiche, nelle aziende/enti pubblici e privati operanti nel settore dei servizi e nello specifico: laboratori di ricerca e sviluppo e reparti di produzione e controllo di qualità nelle imprese biotecnologiche ed altre imprese interessate all’innovazione _biotecnologia quali le imprese chimiche (chimica fine, bioenergetica, materiali innovativi), farmaceutiche, agro-­‐alimentari, imprese interessate alla utilizzazione di sistemi biologici per microsensori; laboratori di diagnostica; laboratori di sviluppo e produzione di saggi molecolari e/o cellulari; laboratori di sviluppo e produzione di biosensori e sistemi innovativi per la diagnostica ed il monitoraggio ambientale; aziende di servizi negli ambiti connessi con le biotecnologie industriali (e.g. laboratori di analisi e di controllo biologico, di pianificazione di attività industriali orientate allo sviluppo sostenibile; enti preposti al monitoraggio e recupero ambientale; enti preposti alla elaborazione di brevetti. 3-­‐ Allocazione nell’ambito del SSN. 5 2. Collegio dei docenti Membri del collegio (personale docente delle università italiane) Cognome Nome Ruolo selezione tra le Ateneo Dipartimento/str Qualifica seguenti opzioni: (menu a uttura Coordinatore; Componente del gruppo dei 16 docenti di riferimento; Altro Componente Riccardi Carlo Achilli Coordinatore e Componente gruppo 16 tendina: I fascia II fascia, RU indet, RU det.) Macro-­‐
settore concorsuale AREA Perugia Dip. di Medicina I fascia 05/G1 05 Alessan Componente dro gruppo 16 Perugia Dip. Chimica, Biologia e Biotecnologie RU 05/E1 05 Avenia Nicola Componente gruppo 16 Perugia Dip. Di Scienze Chirurgiche e Biomediche II fascia 06/C1 06 Ayroldi Emira Altro Componente Perugia Dip. di Medicina II fascia 05/G1 05 Bruscoli Stefano Altro Componente Perugia Dip. di Medicina RU 05/G1 05 Cardinali Gianlui Altro Componente Perugia gi Dip. Di Scienze Farmaceutiche II fascia 07/F2 07 Corazzi Lanfran Altro Componente Perugia co Dip. Di Medicina I fascia Sperimentale 05/E1 05 Cossignani Lina Dip. Di Scienze Farmaceutiche II fascia 03/D1 03 Cruciani Gabriel Componente e gruppo 16 Dip. Chimica, Biologia e Biotecnologie I fascia 03/c1 03 Delfino Domen Altro Componente Perugia ico Dip. di Medicina II fascia 05/G1 05 Elia A.Conc Altro Componente Perugia etta Dip. Chimica, Biologia e Biotecnologie RU 05/C1 05 Elisei Fausto Componente gruppo 16 Perugia Dip. Chimica, Biologia e Biotecnologie I fascia 03/A2 03 Emiliani Carla Altro Componente Perugia Dip. Chimica, Biologia e Biotecnologie I fascia 05/E1 05 Fabiani Robert Altro Componente Perugia o Dip. Chimica, Biologia e Biotecnologie II fascia 06/M1 06 Fagotti Anna Dip. Di Scienze Chirurgiche e Biomediche RU 06/H1 06 Federici Ermann Altro Componente Perugia o Dip. Chimica, Biologia e Biotecnologie RU 05/I1 05 Fettucciari Katia Dip. Di Medicina RU Sperimentale 06/A2 02 Altro Componente Perugia Componente Gruppo 16 Perugia Perugia Altro Componente Perugia 6 Franciolini Fabio Altro Componente Perugia Dip. Chimica, Biologia e Biotecnologie I fascia 05/D1 05 Fioretto Daniele Componente gruppo 16 Perugia Dip. Di Fisica e Geologia I fascia 02/A2 02 Gammaitoni Luca Perugia Dip. Di Fisica e Geologia I fascia 02/A1 02 Galli Frances Altro Componente Perugia co Dip. Di Scienze Farmaceutiche RU 05/E1 05 Gerli Robert Componente o gruppo 16 Dip. Di Scienze Chirurgiche e Biomediche I fascia 06/D3 06 Germani Raimon Altro Componente Perugia do Dip. Chimica, Biologia e Biotecnologie I fascia 03/C1 03 Gigliotti Giovan Componente ni gruppo 16 Perugia Dip. Scienze Agrarie e Ambiantali I fascia 07/E1 07 Grignani Franco Componente gruppo 16 Perugia Dip. Di Medicina I fascia Sperimentale 06/A2 06 Latterini Loreda Componente na gruppo 16 Perugia Dip. Chimica, Biologia e Biotecnologie II fascia 03/A2 03 Marcotullio Carla Perugia Dip. Di Scienze Farmaceutiche II fascia 05/G1 05 Martino Sabata Altro Componente Perugia Dip. Di Chimica, Biologia e Biotecnologie RU 05/E2 05 Mecocci Patrizia Componente gruppo 16 Perugia Dip. Di Medicina I fascia 06/B1 06 Migliorati Graziell Altro Componente Perugia a Dip. di Medicina I fascia 05/G1 05 Minelli Liliana Altro Componente Perugia Dip. Di Medicina RU Sperimentale 06/M1 06 Nocentini Giusep Altro Componente Perugia pe Dip. Di Medicina II fascia 05/G1 05 Pasqualini Stefani Altro Componente Perugia a Dip. Chimica, Biologia e Biotecnologie 05/A2 05 Puxeddu Efisio Dip. Di Medicina RU 06/N1 06 Rebora Manuel Altro Componente Perugia a Dip. Di Chimica, Biologia e Biotecnologie 05/B1 05 Roberti Rita Altro Componente Perugia Dip. Di Medicina II fascia Sperimentale 05/E1 05 Ronchetti Simona Altro Componente Perugia Dip. di Medicina II fascia 05/G1 05 Rosati Emanu Altro Componente Perugia ela Dip. Di Medicina RU Sperimentale 06/A2 06 Schillaci Giusep Componente pe gruppo 16 Dip. di Medicina II fascia 06/B1 06 Simonetti Stella Dip. Di Scienze Farmaceutiche 03/D1 03 Componente gruppo 16 Componente gruppo 16 Perugia Altro Componente Perugia Perugia Altro Componente Perugia II fascia RU I fascia 7 Spinozzi Fabrizi Altro Componente Perugia o Dip. di Medicina II fascia 06/B1 06 Tancini Brunell Altro Componente Perugia a Dip. Chimica, Biologia e Biotecnologie RU 05/E1 05 Vaccaro Luigi Dip. Chimica, Biologia e Biotecnologie II fascia 03/C1 03 Componente gruppo 16 Perugia 8 Membri del collegio (personale non accademico dipendente di altri enti e personale docente di università straniere) Cognome Nome Ruolo Ateneo/Ent Tipo di ente: Paese Diparti Qualifica AREA ERC selezione tra le (selezione t
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truttura Professore di opzioni: Università Componente del za straniera; ente di Università gruppo dei 16 docenti di riferimento; Altro Componente ricerca; impresa che svolge attività di ricerca e sviluppo) straniera, Ricercatore di Università straniera; Dirigente di ricerca; Primo ricercatore, ricercatore, esperto di cui all’art. 6, c.4 Biffi Alessa Altro Istituto San Ente di Componente ndra Raffaele ricerca Milano Italia TIGET-­‐
HSR Primo Ricercatore LS_9 Gritti Angela Altro Italia TIGET-­‐
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na (PG) -­‐ Italy LS_9 9 Produzione scientifica dei membri del collegio nell’arco degli ultimi 5 anni: indicare per ciascuno le 5 pubblicazioni ritenute più significative 1.
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Riccardi Carlo S. Cuzzocrea, S. Bruscoli, E. Mazzon, C. Crisafulli, V. Donato, R. Di Paola, E. Velardi, E. Esposito, G. Nocentini, and C. Riccardi. Peroxisome Proliferator-­‐Activated Receptor-­‐ Contributes to the Anti-­‐
Inflammatory Activity of Glucocorticoids.Mol. Pharmacol., 73(2), 323-­‐337, 2008. G.W. O’Keeffe H. Gutierrez, P. P. Pandolfi, C.Riccardi, and A. M. Davie NGF-­‐promoted axon growth and target innervation requires GITRL-­‐GITR signalling. Nat. Neurosci., 11(2),135-­‐142, 2008. G. Nocentini , S. Cuzzocrea, T. Genovese, R. Bianchini, E. Mazzon, S. Ronchetti, E. Esposito, R. Di Paola, P. Bramanti, and C. Riccardi. Glucocorticoid-­‐induced tumor necrosis factor receptor-­‐related (GITR)-­‐Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury. Mol. Pharmacol., 73(6), 1610-­‐1621, 2008. S. Chen, LC. Ndhlovu, T. Takahashi, K. Takeda, Y. Ikarashi, T. Kikuchi, K. Murata, PP. Pandolfi, C. Riccardi, M. Ono, K. Sugamur, and N. Ishi. Co-­‐inhibitory roles for glucocorticoid-­‐induced TNF receptor in CD1d-­‐
dependent natural killer T cells. Eur. J. Immunol., 38(8), 2229-­‐2240, 2008 B. Cinque, D. Fanini, L. Di Marzio, P. Palumbo, C. La Torre, V. Donato, E. Velardi, S. Bruscoli, C. Riccardi, and M.G. Cifone. Involvement of cPLA2 inhibition in dexamethasone-­‐induced thymocyte apoptosis. Int. J. Immunopathol. Pharmacol., 21(3), 539-­‐551, 2008 L. Cannarile, S. Cuzzocrea, L. Santucci, M. Agostini, E. Mazzon, E. Esposito, C. Muià, M. Coppo, R. Di Paola, and C. Riccardi. Glucocorticoid-­‐Induced Leucine Zipper Is Protective in Th1-­‐Mediated Models of Colitis. Gastroenterology, 136(2), 530-­‐541, 2009. L. Riccardi E. Mazzon, S. Bruscoli, E. Esposito, C. Crisafulli, R. Di Paola, R. Caminiti, C. Riccardi, and S. Cuzzocrea. Peroxisome proliferator-­‐activated receptor-­‐alpha modulates the anti-­‐inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice. Shock, 31(3), 308-­‐316, 2009 R. Gerli, G. Nocentini, A. Alunno, E. Bartoloni Bocci, R. Bianchini, O. Bistoni, and C. Riccardi Identification of regulatory T cells in systemic lupus erythematosus. Autoimmun. Rev., 8(5), 426-­‐430, 2009. A. Vecchiarelli, E. Pericolini, E. Gabrielli, M. Agostini, F. Bistoni, G. Nocentini, E. Cenci, C. Riccardi The GITRL-­‐GITR system alters TLR-­‐4 expression on DC during fungal infection. Cell. Immunol., 257(1-­‐2),13-­‐22, 2009. E. Ayroldi, C. Riccardi. Glucocorticoid-­‐induced leucine zipper (GILZ): a new important mediator of glucocorticoid action.FASEB J, 23(11), 3649-­‐3658, 2009. G. Nocentini, C. Riccardi. GITR: A Modulator of Immune Response and Inflammation. Adv. Exp. Med. Biol. 647,156-­‐173, 2009 G. Cantarella, G. Di Benedetto, I. Paternità, S. Cuzzocrea, G. Nocentini, P. Bosco, C. Riccardi and R. Bernardini. Neutralization of tumor necrosis factor related apoptosis inducing ligand (TRAIL) reduces spinal cord injurin damage in mice. Neuropsychopharmacology, 35(6), 1302-­‐1314, 2010. E. Tamayo, J. Postigo, J. González, M. Fernández-­‐Rey, M. Iglesias, I. Santiuste, C. Riccardi, R. Rappuoli, G. Del Giudice, R. Merino, J. Merino. The Glucocorticoid-­‐induced TNFR-­‐related protein (GITR) contributes to the systemic adjuvanticity of the Escherichia coli heat-­‐labile enterotoxin. Eur. J. Immunol. 40(3), 754-­‐763, 2010 L. M. Snell, Ann J. McPherson, Gloria H.Y. Lin, Shimon Sakaguchi, Pier P. Pandolfi, Carlo Riccardi , and Tania H. Watts. CD8 cell intrinsic GITR is required for T cell clonal expansion and mouse survival following severe respiratory influenza infection. J. Immunol., 185(12), 7223-­‐7234, 2010. S. Bruscoli, V. Donato, E. Velardi, M. Di Sante, G. Migliorati, R. Donato and C. Riccardi. Glucocorticoid-­‐
Induced Leucine Zipper (GILZ) and Long-­‐GILZ inhibit myogenic differentation and mediate anti-­‐myogenic effects of glucocorticoids. J. Biol. Chem., 285(14),10385-­‐10396, 2010. Gharagozloo M, Velardi E, Bruscoli S, Agostini M, Di Sante M, Donato V, Amirghofran Z, Riccardi C. Silymarin suppress CD4+ T cell activation and proliferation: Effects on NF-­‐kappaB activity and IL-­‐2 production. Pharmacol. Res, 61(5),405-­‐409, 2010. T. Broccoletti, E. Del Giudice, E. Cirillo, I. Vigliano, G. Giardino, V.M. Ginocchio, S. Bruscoli, C. Riccardi and C. Pignata. Efficacy of very-­‐low-­‐dose betamethasone on neurological symptoms in ataxia-­‐telangiectasia. Eur. J. Neurol., 18(4), 564-­‐570, 2011. S. Ronchetti, G. Nocentini, M.G. Petrillo, R. Bianchini, P. Sportoletti, A. Bastianelli, E. Ayroldi and C. Riccardi. Glucocorticoidi-­‐Induced TNFR family Related gene (GITR) enhances dendritic cell activity. Immunol. Lett., 135(1-­‐2), 24-­‐33, 2011. 10 21. M. Galuppo; G. Nocentini , E. Mazzon, S. Ronchetti, E. Esposito, L. Riccardi, P. Sportoletti, R. Di Paola, S. 22.
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Bruscoli, C. Riccardi and S. Cuzzocrea. The glucocorticoid-­‐induced TNF receptor family-­‐related protein (GITR) is critical to the development of acute pancreatitis in mice. Br. J. Pharmacol., 162(5), 1186-­‐1201, 2011 D. V. Delfino, S. Spinicelli, N. Pozzesi, S. Pierangeli, E. Velardi, S. Bruscoli, MP. Martelli, V. Pettirossi, L. Falchi, T-­‐b Kang and C. Riccardi. Glucocorticoid-­‐induced activation of caspase-­‐8 protects the glucocorticoid-­‐induced protein Gilz from proteasomal degradation and induces its binding to Sumo-­‐1 in murine thymocytes. Cell. Death Differ., 18(1), 183-­‐190, 2011. V. Ceccarelli, G. Nocentini, C. Riccardi, E. Ayroldi, P. Di Nardo, R. Roberti, L. Binaglia and A. Vecchini Effect of dietary saturated fatty acid on HNF-­‐4alfa DNA binding activity and ApoCIII mRNA in sedentary rat liver. Mol. Cell. Biochem., 347(1-­‐2), 29-­‐39, 2011. N. Pozzesi, S. Pierangeli, C.Vacca, L. Falchi, V. Pettorossi, M.P. Martelli, T.T. Thuy, P.T. Ninh, A.M. Liberati, C. Riccardi, T.V. Sung and D.V. Delfino. Maesopsin 4-­‐O-­‐beta-­‐D-­‐glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-­‐regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia. J. Chemother., 23(3), 150-­‐157, 2011 V. Ceccarelli, S. Racanicchi, M.P. Martelli, G. Nocentini, K. Fettucciari, C. Riccardi, P. Marconi, P. Di Nardo, F. Grignani, L. Binaglia and A. Vecchini. Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhan cer-­‐binding protein delta in U937 leukemia cells. J. Biol. Chem., 286(31), 27092-­‐27102, 2011. R. Bianchini, O. Bistoni, A. Alunno, M.G. Petrillo, S. Ronchetti, P. Sportoletti, E. Bartoloni Bocci, G. Nocentini, R. Gerli and C. Riccardi. CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-­‐cell population with regulatory activity. Eur. J. Immunol., 41(8), 2269-­‐2278, 2011. M. Galuppo, G. Nocentini, E. Mazzon, S. Ronchetti, E. Esposito, L. Riccardi, R. Di Paola, S. Bruscoli, C. Riccardi and S. Cuzzocrea. GITR gene deletion and GITR-­‐FC soluble protein administration inhibit multiple organ failure induced by zymosan. Shock, 36(3), 263-­‐271, 2011 E. Esposito, S. Bruscoli, E. Mazzon, I. Paterniti, M. Coppo, E. Velardi, S. Cuzzocrea and C. Riccardi Glucocorticoid-­‐induced leucine zipper (GILZ) over–expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury. Neurotherapeutics, 9(1),210-­‐225, 2012 G. Nocentini, S. Ronchetti, M.G. Petrillo and C. Riccardi, Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.Br. J. Pharmacol., 165(7), 2089-­‐2099, 2012 S. Bruscoli, E. Velardi, M. Di Sante, O. Bereshchenko, A. Venanzi, M. Coppo, V. Berno, M. G. Mameli, R. Colella, A. Cavaliere and C. Riccardi. Long-­‐Glucocorticoid-­‐Induced Leucine Zipper (L-­‐GILZ) interacts with Ras pathway and contributes to spermatogenesis control. J. Biol. Chem., 287(2),1242-­‐1251, 2012. L. Sinik Teodorovic, C. Riccardi, R.M. Torres and R. Pelanda. Murine B Cell Development and Antibody Responses to Model Antigens Are Not Impaired in the Absence of the TNF Receptor GITR. PLoS One, (2),e31632. S. Ronchetti, G. Nocentini, M.G. Petrillo, C. Riccardi.CD8(+) T Cells: GITR Matters. ScientificWorld Journal, 2012;2012:308265. A. Alunno, E. Bartoloni, O. Bistoni, G. Nocentini, S. Ronchetti, S. Caterbi, V. Valentini, C. Riccardi and R. Gerli Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New. Clin Dev Immunol., 2012;2012:823085. O. Bereshchenko, E. Mancini, L. Luciani, A. Gambardella, C. Riccardi and C. Nerlov. Pontin is essential for murine hematopoietic stem cell survival. Haemathologica, 2012; 97:1291-­‐1294. L. McKlvey, H. Gutierrez, G. Nocentini, SJ Crampton, AM Davies, C. Riccardi, CW O’keeffe. The intracellular portion of GITR enhances NGF-­‐promoted neurite growth through an inverse modulation of Erk and NF-­‐κB signaling. Biol Open, 2012; 1(10): 1016-­‐1023. E. Ayroldi, L.Cannarile, G. Migliorati, G. Nocentini, DV. Delfino, C. Riccardi. Mechanisms of the anti-­‐
inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways. FASEB J. 2012; 26(12): 4805-­‐20. Libri didattici Riccardo Carlo (codici CB) Riccardi C., Migliorati G. (2012). Modulazione farmacologica del sistema immune. In: Clementi F., Fumagalli G. Farmacologia generale e molecolare "IV Edizione". p. 559-­‐574, Torino: UTET – Torino F.Rossi, V. Cuomo, C. Riccardi (2011). Farmacologia Principi di base e applicazioni terapeutiche II Edizione. Torino: Edizioni Minerva Medica Riccardi C. (a cura di) (2011). Farmaci del sistema immunitario. Di Rossi F., Cuomo V., Riccardi C. In "FARMACOLOGIA Principi di base e applicazioni terapeutiche II Edizione". p. 815-­‐836, Torino: Edizioni Minerva Medica 11 42. Riccardi C. (a cura di) (2011). Farmaci dell'infiammazione. Di Rossi F., Cuomo V., Riccardi C. In 43.
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Inhibition of cell cycle progression by hydroxytyrosol is associated with the up-­‐regulation of CDK inhibitors p21WAF1/Cip1 and p27Kip1, and with the induction of differentiation in HL60 cells. J. Nutr. 138: 42-­‐48. 28 356. Fabiani R, Rosignoli P, De Bartolomeo A, Fuccelli R, Servili M, Montedoro GF, Morozzi G (2008). Oxidative DNA damage is prevented by extracts of olive oil, hydroxytyrosol, and other olive phenolic compounds in human blood mononuclear cells and HL60 cells. J. Nutr. 138: 1411-­‐1416 Fagotti Anna 357. Rossitto C, Gagliardi ML, Fagotti A, Fanfani F, Gallotta V, Scambia G. Teaching and training in laparoscopic surgery: experience of Catholic Laparoscopy Advanced Surgery School in the basic gynecological surgery Arch Gynecol Obstet..2012 358. Fanfani F, Rossitto C, Gagliardi ML, Gallotta V, Gueli Alletti S, Scambia G, Fagotti A. Total laparoendoscopic single-­‐site surgery (LESS) hysterectomy in low-­‐risk early endometrial cancer: a pilot study Surg Endosc.2012 359. Prisco MG, Zannoni GF, De Stefano I, Vellone VG, Tortorella L, Fagotti A, Mereu L, Scambia G, Gallo D. Prognostic role of metastasis tumor antigen 1 in patients with ovarian cancer: a clinical study Hum Pathol.2012 360. Maneo A, Sideri M, Scambia G, Boveri S, Dell'anna T, Villa M, Parma G, Fagotti A, Fanfani F, Landoni .. Simple conization and lymphadenectomy for the conservative treatment of stage IB1 cervical cancer. An Italian experience. Gynecol Oncol 2012 361. Testa AC, Ludovisi M, Mascilini F, Di Legge A, Malaggese M, Fagotti A, Fanfani F, Salerno MG, Ercoli A, Scambia G, Ferrandina G. Ultrasound evaluation of intra-­‐abdominal sites of disease to predict likelihood of suboptimal cytoreduction in advanced ovarian cancer: a prospective study .Ultrasound Obstet Gynecol. 2012 362. Gallotta V, Fanfani F, Vizzielli G, Panico G, Rossitto C, Gagliardi ML, Margariti PA, Salerno MG, Zannoni GF, Pacelli F, Scambia G, Fagotti A. Douglas peritonectomy compared to recto-­‐sigmoid resection in optimally cytoreduced advanced ovarian cancer patients: analysis of morbidity and oncological outcome Eur J Surg Oncol.2012 363. Zannoni GF, Prisco MG, Vellone VG, De Stefano I, Vizzielli G, Tortorella L, Fagotti A, Scambia G, Gallo D. Cytoplasmic expression of oestrogen receptor beta (ERβ) as a prognostic factor in vulvar squamous cell carcinoma in elderly women.Histopatholog.2012 364. Ercoli A, D'asta M, Fagotti A, Fanfani F, Romano F, Baldazzi G, Salerno MG, Scambia G. Robotic treatment of colorectal endometriosis: technique, feasibility and short-­‐term results.Hum Reprod. 2012 365. Fagotti A, Boruta DM 2nd, Scambia G, Fanfani F, Paglia A, Escobar PF .First 100 early endometrial cancer cases treated with laparoendoscopic single-­‐site surgery: a multicentric retrospective study. Am J Obstet Gynecol.2012 366. Fagotti A, Gagliardi ML, Fanfani F, Salerno MG, Ercoli A, D'Asta M, Tortorella L, Turco LC, Escobar P, Scambia G.. Perioperative outcomes of total laparoendoscopic single-­‐site hysterectomy versus total robotic hysterectomy in endometrial cancer patients: a multicentre study. Gynecol Oncol .2012 367. Vizzielli G, Fanfani F, Costantini B, Gallotta V, Scambia G, Fagotti A. External hemipelvectomy as treatment for solitary coxofemoral metastasis from endometrial carcinoma: case report and review of the literature. J Obstet Gynaecol Res.2012 368. Fagotti A, De Iaco P, Fanfani F, Vizzielli G, Perelli F, Pozzati F, Perrone AM, Turco LC, Scambia G. Systematic pelvic and aortic lymphadenectomy in advanced ovarian cancer patients at the time of interval debulking surgery: a double-­‐institution case-­‐control study. Ann Surg Oncol. 2012 369. Fanfani F, Fagotti A, Rossitto C, Gagliardi ML, Ercoli A, Gallotta V, Gueli Alletti S, Monterossi G, Turco LC, Scambia G. Laparoscopic, minilaparoscopic and single-­‐port hysterectomy: perioperative outcomes. Surg Endosc. 2012 370. Fagotti A, Ludovisi M, De Blasis I, Virgilio B, Di Legge A, Mascilini F, Moruzzi M, Giansiracusa C, Fanfani F, Tropeano G, Di Bidino R, Scambia G, Testa A. The sonographic prediction of invasive carcinoma in unilocular-­‐solid ovarian cysts in premenopausal patients: a pilot study Hum Reprod. 2012 371. Fanfani F, Fagotti A, Salerno MG, Margariti PA, Gagliardi ML, Gallotta V, Vizzielli G, Panico G, Monterossi G, Scambia G . Elderly and very elderly advanced ovarian cancer patients: does the age influence the surgical management? Eur J Surg Oncol 2012. 372. Fagotti A, Costantini B, Petrillo M, Vizzielli G, Fanfani F, Margariti PA, Turco LC, Piovano E, Scambia G. Cytoreductive surgery plus HIPEC in platinum-­‐sensitive recurrent ovarian cancer patients: a case-­‐control study on survival in patients with two year follow-­‐up. Gynecol Oncol. 2012 373. Fagotti A, Bottoni C, Vizzielli G, Rossitto C, Tortorella L, Monterossi G, Fanfani F, Scambia G. Laparoendoscopic single-­‐site surgery (LESS) for treatment of benign adnexal disease: single-­‐center experience over 3-­‐years. J Minim Invasive Gynecol.2012 29 374. Ercoli A, Fanfani F, D'Asta M, Naldini A, Pacelli F, Scambia G, Fagotti A. Role of different approaches to the abdominal retroperitoneum for aortic lymphadenectomy in patients with gynecological cancers Eur J Surg Oncol. 2011 375. Ferrandina G, Margariti PA, Smaniotto D, Petrillo M, Salerno MG, Fagotti A, Macchia G, Morganti AG, Cellini N, Long-­‐term analysis of clinical outcome and complications in locally advanced cervical cancer patients administered concomitant chemoradiation followed by radical surgery. Gynecol Oncol 2011 376. Fagotti A, Fanfani F, Marocco F, Rossitto C, Gallotta V, Marana E, Scambia G. Laparoendoscopic single-­‐site surgery for the treatment of benign adnexal diseases: a pilot study Surg Endosc. 2011 377. Fagotti A, Gagliardi ML, Moruzzi C, Carone V, Scambia G, Fanfani F. Excisional cone as fertility-­‐sparing treatment in early-­‐stage cervical cancer. Fertil Steril 2011 378. Fagotti A, Rossitto C, Marocco F, Gallotta V, Bottoni C, Scambia G, Fanfani F Perioperative outcomes of laparoendoscopic single-­‐site surgery (LESS) versus conventional laparoscopy for adnexal disease: a case-­‐-­‐
control study. Surg Innov. 2011 379. Fanfani F, Gagliardi ML, Zannoni GF, Gallotta V, Vizzielli G, Lecca A, Scambia G, Fagotti A.. Total laparoscopic hysterectomy in early-­‐stage endometrial cancer using an intrauterine manipulator: is it a bias for frozen section analysis? Case-­‐control study. J Minim Invasive Gynecol. 2011 380. Mais V, Angioli R, Coccia E, Fagotti A, Landi S, Melis GB, Pellicano M, Scambia G, Zupi E, Angioni S, Arena S, Corona R, Fanfani F, Nappi C,[Prevention of postoperative abdominal adhesions in gynecological surgery. Consensus paper of an Italian gynecologists' task force on adhesions]. Minerva Ginecol 2011 381. Fanfani F, Rossitto C, Fagotti A, Gallotta V, Gagliardi ML, Scambia G. Narrow-­‐band imaging in laparoscopic management of cervical carcinoma. J Minim Invasive Gynecol.2011 382. Fagotti A, Vizzielli G, Scambia G. RE: "Ventral hernia following primary laparotomy for ovarian, fallopian tube, and primary peritoneal cancers". Gynecol Oncol. 2011 383. Fagotti A, Costantini B, Vizzielli G, Perelli F, Ercoli A, Gallotta V, Scambia G, Fanfani F. HIPEC in recurrent ovarian cancer patients: morbidity-­‐related treatment and long-­‐term analysis of clinical outcome. Gynecol Oncol.2011 384. Fagotti A., Bottoni C., Vizzielli G., Alletti S.G., Scambia G., Marana E., Fanfani F. Postoperative pain after conventional laparoscopy and laparoendoscopic single site surgery (LESS) for benign adnexal disease: A randomized trial. Fertiliy and Steriliy 2011 385. De Stefano I, Zannoni GF, Prisco MG, Fagotti A, Tortorella L, Vizzielli G, Mencaglia L, Scambia G, Gallo D. Cytoplasmic expression of estrogen receptor beta (ERβ) predicts poor clinical outcome in advanced serous ovarian cancer. Gynecol Oncol.2011 386. Fagotti A, Vizzielli G, Costantini B, Lecca A, Gallotta V, Gagliardi ML, Scambia G, Fanfani F .Learning curve and pitfalls of a laparoscopic score to describe peritoneal carcinosis in advanced ovarian cancer Acta Obstet Gynecol Scand. 2011 387. Fagotti A, Fanfani F, Vizzielli G, Gallotta V, Ercoli A, Paglia A, Costantini B, Vigliotta M, Scambia G, Ferrandina G. Should laparoscopy be included in the work-­‐up of advanced ovarian cancer patients attempting interval debulking surgery? Gynecol Oncol. 2010 388. Fanfani F, Fagotti A, Scambia G. Laparoendoscopic single-­‐site surgery for total hysterectomy.. Int J Gynaecol Obstet. 2010 389. Fanfani F, Rossitto C, Fagotti A, Rosati P, Gallotta V, Scambia G. Laparoscopic myomectomy at 25 weeks of pregnancy: case report .J Minim Invasive Gynecol.2010 390. Fagotti A, Fanfani F, Rossitto C, Marocco F, Gallotta V, Romano F, Scambia G Laparoendoscopic single-­‐site surgery for the treatment of benign adnexal disease: a prospective trial. Diagn Ther Endosc 2010 391. Fanfani F, Gallotta V, Rossitto C, Fagotti A, Scambia G. Narrow band imaging in borderline ovarian tumor. J Minim Invasive Gynecol. 2010 392. Fagotti A, Costantini B, Fanfani F, Vizzielli G, Rossitto C, Lecca A, Scambia G. Risk of postoperative pelvic abscess in major gynecologic oncology surgery: one-­‐year single-­‐institution experience.Ann Surg Oncol.2010 393. Fagotti A, Vizzielli G, Fanfani F, Scambia G. Comparison of peritoneal carcinomatosis scoring methods in predicting resectability and prognosis in advanced ovarian cancer . Am J Obstet Gynecol. 2010 394. Gallotta V, Fanfani F, Rossitto C, Vizzielli G, Testa A, Scambia G, Fagotti A. A randomized study comparing the use of the Ligaclip with bipolar energy to prevent lymphocele during laparoscopic pelvic lymphadenectomy for gynecologic cancer. Am J Obstet Gynecol. 2010 395. Marocco F, Fanfani F, Rossitto C, Gallotta V, Scambia G, Fagotti A. Laparoendoscopic single-­‐site surgery for fertility-­‐sparing staging of border line ovarian tumors: initial experience. Surg Laparosc Endosc Percutan Tech. 2010 30 396. Fagotti A, Paris I, Grimolizzi F, Fanfani F, Vizzielli G, Naldini A, Scambia G. Secondary cytoreduction plus oxaliplatin-­‐based HIPEC in platinum-­‐sensitive recurrent ovarian cancer patients: A pilot study Oncology 2009 397. Minelli L, Fanfani F, Fagotti A, Ruffo G, Ceccaroni M, Mereu L, Landi S, Pomini P, Scambia G .Laparoscopic colorectal resection for bowel endometriosis: feasibility, complications, and clinical outcome. Arch Surg. 2009 398. Fanfani F, Fagotti A, Gallotta V, Ercoli A, Pacelli F, Costantini B, Vizzielli G, Margariti PA, Garganese G, Scambia G. Upper abdominal surgery in advanced and recurrent ovarian cancer: Role of diaphragmatic surgery. Gynecol Onco 2010 399. Fanfani F, Fagotti A, Gagliardi ML, Ruffo G, Ceccaroni M, Scambia G, Minelli L. Discoid or segmental rectosigmoid resection for deep infiltrating endometriosis: a case-­‐control study .Fertil Steril.2010 400. Fagotti A, Gallotta V, Romano F, Fanfani F, Rossitto C, Naldini A, Vigliotta M, Scambia G. Peritoneal carcinosis of ovarian origin .World J Gastrointest Oncol. 2010 401. Ercoli A, Iannone V, Legge F, Fagotti A, Fanfani F, Carone V, D'Asta M, Scambia G, Ferrandina G. Advances in surgical management of cervical cancer.. Minerva Ginecol.2009 402. Fagotti A, Fanfani F, Marocco F, Rossitto C, Gallotta V, Scambia G. Laparoendoscopic single-­‐site surgery (LESS) for ovarian cyst enucleation: report of first 3 cases. Fertil Steril. 2009 403. Ercoli A, Delmas V, Iannone V, Fagotti A, Fanfani F, Corrado G, Ferrandina G, Scambia G. The lymphatic drainage of the uterine cervix in adult fresh cadavers: anatomy and surgical implications Eur J Surg Oncol. 2009 404. Ferrandina G, Sallustio G, Fagotti A, Vizzielli G, Paglia A, Cucci E, Margariti A, Aquilani L, Garganese G, Scambia G. Role of CT scan-­‐based and clinical evaluation in the preoperative prediction of optimal cytoreduction in advanced ovarian cancer: a prospective trial. Br J Cancer 2009 405. Fanfani F, Fagotti A, Ferrandina G, Raspagliesi F, Ditto A, Cerrotta AM, Morganti A, Smaniotto D, Scambia G. Neoadjuvant chemoradiation followed by radical hysterectomy in FIGO Stage IIIB cervical cancer: feasibility, complications, and clinical outcome. Int J Gynecol Cancer 2009 406. Fagotti A, Fanfani F, Rossitto C, Lorusso D, De Gaetano AM, Giordano A, Vizzielli G, Scambia G .A treatment selection protocol for recurrent ovarian cancer patients: The role of FDG-­‐PET/CT and staging laparoscopy Gynecol Oncol 2008 407. Fagotti A, Ferrandina G, Fanfani F, Garganese G, Vizzielli G, Carone V, Salerno MG, Scambia G Prospective validation of a laparoscopic predictive model for optimal cytoreduction in advanced ovarian carcinoma Am J Obstet Gynecol. 2008 408. Ferrandina G, Fanfani F, Ludovisi M, Fagotti A, Carbone A, Zannoni G, Guerriero M, Petrillo M, Scambia G .Is frozen section analysis of pelvic lymph nodes accurate in locally advanced cervical cancer patients administered preoperative chemoradiation? Gynecol Oncol 2008 Federici Ermanno 409. 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6106. 2009 31 416. Quaratino D, Ciaffi M, Federici E, D’annibale A . Response surface methodology study of laccase production in Panus tigrinus liquid cultures. Biochem. Eng. J. 39: 236–45.2008 417. Leonardi V., Giubilei M.A., Federici E., Spaccapelo R., Sasek V., Novotny C., Petruccioli A., D'Annibale A. (2008). Mobilizing agents enhance fungal degradation of polycyclic aromatic hydrocarbons and affect diversity of indigenous bacteria in soil. Biotechnol. Bioeng. 101:273-­‐85-­‐ 2008 Fettucciari Katia 418. Del Papa B., Sportoletti P., Cecchini D.,Rosati E., Balucani C., Baldoni S., Fettucciari K., Marconi P.,Martelli MF., Falzetti F., Di Ianni M. Notch1 modulates Mesenchymal stem cells-­‐mediated regulatory T cell induction EUROPEAN JOURNAL OF IMMUNOLOGY. 2012 419. Rosati E.,Sabatini R., De Falco F., Del Papa B., Falzetti F., Di Ianni M.,Cavalli L., Fettucciari K., Bartoli A.,Screpanti I., Marconi P. γ-­‐Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and Notch down-­‐regulation. INTERNATIONAL JOURNAL OF CANCER . 2012 420. Antognelli C., Mezzasoma L., Fettucciari K., Mearini E., Talesa VN. Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells. PROSTATE. 2012 421. Ceccarelli V., Racanicchi S., Martelli MP., Nocentini G., Fettucciari K., Riccardi C., Marconi P., Di Nardo P., Grignani F., Binaglia L., Vecchini A Eicosapentaenoic acid demethylates a single CpG thatmediates expression of tumor suppressor CCAAT/enhancer-­‐binding protein delta in U937 leukemia cells. THE JOURNAL OF BIOLOGICAL CHEMISTRY.2011 422. Fettucciari K., Quotadamo F., Noce R., Palumbo C.,Modesti A., Rosati E., Mannucci R.,Bartoli A.,Marconi P. Group B Streptococcus (GBS) disrupts by calpain activation the actin and microtubulo cytoskeleton of macrophages CELLULAR MICROBIOLOGY. 2011 423. Rosati E.,Sabatini R., Rampino G., De Falco F., Di Ianni M., Falzetti F., Fettucciari K., Bartoli A.,Screpanti I., Marconi P. Novel targets for endoplasmic reticulum stress-­‐induced apoptosis in B-­‐CLL. BLOOD. 2010 424. Susta F., Chiasserini D., Fettucciari K., Orvietani PL., Quotadamo F., Noce R.,Bartoli A., Marconi P.,Corazzi L., Binaglia L. Protein expression changes induced in murine peritoneal macrophagesby Group B Streptococcus. PROTEOMIC. 2010 425. Rosati E., Sabatini R., Rampino G.,Tabilio A., Di Ianni M., Fettucciari K., Bartoli A.Coaccioli S.,Screpanti I., MarconiP. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-­‐CLL cells. BLOOD. 2009 Franciolini Fabio 426. Ruggieri P, Mangino G, Fioretti B, Catacuzzeno L, Puca R, Ponti D, Miscusi M, Franciolini F, Ragona G, Calogero A. The inhibition of KCa3.1 channels activity reduces cell motility in glioblastoma derived cancer stem cells. PLoS One. 2012: 7:e47825. 427. Catacuzzeno L, Fioretti B, Franciolini F. Expression and Role of the Intermediate-­‐Conductance Calcium-­‐
Activated Potassium Channel KCa3.1 in Glioblastoma. J Signal Transduct. 2012; 2012:421564. 428. Catacuzzeno L, Fioretti B, Franciolini F. A theoretical study on the role of Ca-­‐activated K channels in the regulation of hormone-­‐induced Ca oscillations and their synchronization in adjacent cells. J Theor Biol. 2012: 21;309:103-­‐12. 429. Fioretti B, Catacuzzeno L, Sforna L, Gerke-­‐Duncan MB, van den Maagdenberg AM, Franciolini F, Connor M, Pietrobon D. Trigeminal ganglion neuron subtype-­‐specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine. J Physiol. 2011; 589:5879-­‐95. 430. Catacuzzeno L, Aiello F, Fioretti B, Sforna L, Castigli E, Ruggieri P, Tata AM, Calogero A, Franciolini F. Serum-­‐activated K and Cl currents underlay U87-­‐MG glioblastoma cell migration. J Cell Physiol. 2011; 226:1926-­‐33. 431. Morpurgo G, Babudri N, Fioretti B, Franciolini F, Catacuzzeno L. Synthetic aromatic compounds interfering with melanogenesis are responsible of the rising trend of malignant melanoma incidence. Med Hypotheses. 2011; 76:374-­‐7 432. Sciaccaluga M, Fioretti B, Catacuzzeno L, Pagani F, Bertollini C, Rosito M, Catalano M, D'Alessandro G, Santoro A, Cantore G, Ragozzino D, Castigli E, Franciolini F, Limatola C. CXCL12-­‐induced glioblastoma cell migration requires intermediate conductance Ca-­‐activated K channel activity. Am J Physiol Cell Physiol. 2010; 299:C175-­‐84. 32 433. Fioretti B, Catacuzzeno L, Sforna L, Aiello F, Pagani F, Ragozzino D, Castigli E, Franciolini F. Histamine hyperpolarizes human glioblastoma cells by activating the intermediate-­‐conductance Ca-­‐activated K channel. Am J Physiol Cell Physiol. 2009;297: C102-­‐10. 434. Catacuzzeno L, Fioretti B, Pietrobon D, Franciolini F. The differential expression of low-­‐threshold K currents generates distinct firing patterns in different subtypes of adult mouse trigeminal ganglion neurones. J Physiol. 2008; 586:5101-­‐18. 435. Catacuzzeno L, Fioretti B, Franciolini F. Modeling study of the effects of membrane surface charge on calcium microdomains and neurotransmitter release. Biophys J. 2008; 95:2160-­‐71. 436. Fioretti B, Trequattrini C, Sforna L, Harper A, Catacuzzeno L, Franciolini F. Cromakalim activates the KATP and enhances spontaneous transient outward potassium currents in rat saphenous arterial myocytes. Pharmacol Res. 2008; 57: 398-­‐402. Fioretto Daniele 437. L.Comez, L.Lupi, A.Morresi, M.Paolantoni, P.Sassi, and D.Fioretto. More Is Different: Experimental Results on the Effect of Biomolecules on the Dynamics of Hydration Water. Journal of Physical Chemistry Letters.2012 438. L. Comez, C. Masciovecchio, G.Monaco, D. Fioretto. Progress in Liquid and Glass Physics by Brillouin Scattering. 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E. Gallina, L. Comez, A. Morresi, M. Paolantoni, S. Perticaroli, P. M. E. Gallina, L. Comez, A. Morresi, M. Paolantoni, S. Perticaroli, P. Rotational dynamics of trehalose in aqueous solutions studied by depolarized light scattering. JOURNAL OF CHEMICAL PHYSICS. 2010 458. S. Perticaroli, L. Comez, M. Paolantoni, P. Sassi, L. Lupi, D. Fioretto, A. Paciaroni, and A. Morresi. Broadband Depolarized Light Scattering Study of Diluted Protein Aqueous Solutions. JOURNAL OF PHYSICAL CHEMISTRY B. 2010 459. S. Corezzi, D.Fioretto, C. De Michele, E. Zaccarelli, F. Sciortino. Modeling the Crossover between Chemically and Diffusion. JOURNAL OF PHYSICAL CHEMISTRY B. 2010 460. S. C. Santucci, L. Comez, F. Scarponi, G. Monaco, R. Verbeni, J.-­‐F.. Onset of the alpha-­‐relaxation in the glass-­‐forming solution. JOURNAL OF PHYSICAL CHEMISTRY B.2010 461. M. Paolantoni, L. Comez, M. E. Gallina, P. Sassi, F. Scarponi, D. 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S.Corezzi, C.De Michele, E.Zaccarelli, D.Fioretto and F.Sciortino. S.Corezzi, C.De Michele, E.Zaccarelli, D.Fioretto and F.Sciortino. A molecular dynamics study of chemical gelation in a patchy particle model. Soft Matter 2008 466. D.Fioretto, S.Corezzi, S.Caponi, F.Scarponi, G.Monaco, A.Fontana and L.Palmieri. Cauchy relation in relaxing liquids. JOURNAL OF CHEMICAL PHYSICS. 2008 467. L.Orsinger, M.Calicchio, G.Carini JR, R.Dal Maschio, D.Fioretto, A.Fontana, P.Fumagalli, E.Gilioli, M.Mattarelli, E.Moser and F.Rossi. Optical and spectroscopic characterisation of permanently densified GeO2 glasses. PHILOSOPHICAL MAGAZINE. 2008 468. B.Ruta, G.Monaco, F.Scarponi, D.Fioretto. Brillouin light scattering study of glassy sorbitol. PHILOSOPHICAL MAGAZINE. 2008 469. M.E.Gallina, L.Comez, S.Perticaroli, A.Morresi, A.Cesàro, O.De Giacomo, S.Di Fonzo, A.Gessini, C.Masciovecchio, L.Palmieri, M.Paolantoni, P.Sassi, F.Scarponi, D.Fioretto. Density fluctuations of water-­‐
glucose mixtures studied by Inelastic Ultra-­‐Violet Scattering. PHILOSOPHICAL MAGAZINE. 2008 Galli Francesco 470. Galli F., Battistoni A., Pompella A., Bragonzi A., Gambari R., Pilolli F., Iuliano L.,Piroddi M., Dechecchi M.C., Cabrini G. Oxidative stress and antioxidant therapy in cystic fibrosis Biochim Biophys Acta -­‐ Mol Bases Dis. 2012 471. Piroddi M., Pilolli F., Aritomi M., Galli F. Vitamin E: functional and biocompatibility modifier of synthetic hemodyaliser membranes -­‐ An overview of the literature on vitamin E-­‐modified hemodialyzer membranes .Am J Nephrol.2012 472. Bellezza I, Tucci A, Galli F, Grottelli S, Mierla AL, Pilolli F, Minelli A. Inhibition of NF-­‐κB nuclear translocation via HO-­‐1 activation underlies α-­‐tocopheryl succinate toxicity .J Nutr Biochem.2012 473. Dessì M, Noce A, Dawood KF, Galli F, Taccone-­‐Gallucci M, Fabrini R, Bocedi A, Massoud R, Fucci G, Pastore A, Manca di Villahermosa S, Zingaretti V, Federici G, Ricci G. Erythrocyte glutathione transferase: a potential new biomarker in chronic kidney diseases which correlates with plasma homocysteine. Amino Acids. 2012 34 474. Murdolo G., Piroddi M., Luchetti F., Tortoioli C., Canonico B., Iuliano L., Galli F. Oxysterols and lipid peroxidation products at the crossroad between adipose oxidative stress and insulin resistance. Biochimie.2012 475. Galli F, Cadenas E Protein post-­‐translational modifications in cell signalling and disease Free Radic Res. 2011 476. Ambrogini P, Minelli A, Floridi A, Lattanzi D, Ciuffoli S, Bucherelli C, Prospero E, Frontini A, Santarelli L, Baldi E, Benetti F, Galli F, Cuppini . Maternal dietary loads of alpha-­‐tocopherol depress protein kinase c (PKC) signaling and synaptic plasticity in rat postnatal developing hippocampus and promote permanent deficits in adult offspring. J Nutr Biochem. 2011 477. Galli F., Mazzini F., Bamonti L, Gille L, Böhmdorfer S, Piroddi M, Netscher T, Kelly F. J., Rosenau T Tocotrienamines and tocopheramines: Reactions with radicals and metal ions. Bioorganic & Medicinal Chemistry. 2011 478. Viola V, Pilolli F, Piroddi M, Pierpaoli E, Orlando F, Provinciali M, Betti M, Mazzini F, Galli. Why tocotrienols work better: insights into the in vitro anti-­‐cancer mechanism of vitamin E. Genes Nutr..2011 479. Varga Z., and Galli F. Regulation of neutrophil functions and signaling by vitamin E compounds. In “Tocopherol: sources, uses and health benefits Catala A. Ed Nova Science Publishers.2011 480. Mandolfo S, Corradi B, Bucci R, Farina M, Pilolli F, Galli F. Evaluation of the impact of a new synthetic vitamin E-­‐bonded membrane on anemia and rHuEPO requirement in ESRD patients with central venous catheters: a pilot study. Int Urol Nephrol. 2011 481. Clerici C, Nardi E, Battezzati PM, Asciutti S, Castellani D, Corazzi N, Giuliano V, Gizzi S, Perriello G, Di Matteo G, Galli F, Setchell KD. Novel soy germ pasta improves endothelial function, blood pressure, and oxidative stress in patients with type 2 diabetes. Diabetes Car. 2011 482. Fusaro M, Crepaldi G, Maggi S, Galli F, D'Angelo A, Calò L, Giannini S, Miozzo D, Gallieni M. Vitamin K, bone fractures, and vascular calcifications in chronic kidney disease: an important but poorly studied relationship J Endocrinol Invest 2011 483. Libetta C., Sepe V., Esposito P., Galli F., Dal Canton A. Oxidative stress and inflammation: implications in uremia and hemodialysis .Clin Biochem. 2011 484. Mazzini F, Betti M, Canonico B, Netscher T, Luchetti F, Papa S, Galli F. Anticancer activity of vitamin E-­‐
derived compounds in murine C6 glioma cells. ChemMedChem. 2010 485. Andrulli S, Di Filippo S, Manzoni C, Stefanelli L, Floridi A, Galli F, Locatelli F Effect of Synthetic Vitamin E-­‐
Bonded Membrane on Responsiveness to Erythropoiesis-­‐Stimulating Agents in Hemodialysis Patients: A Pilot Study Nephron Clin Pract. 2010 486. Pierpaoli E, Viola V, Pilolli F, Piroddi M, Galli F, Provinciali M. Gamma-­‐ and delta-­‐tocotrienols exert a more potent anticancer effect than alpha-­‐tocopheryl succinate on breast cancer cell lines irrespective of HER-­‐
2/neu expression Life Sci 2010 487. Giuliano V, Bassotti G, Mourvaki E, Castellani D, Filippucci E, Sabatino G, Gizzi S, Palmerini F, Galli F, Morelli O, Baldoni M, Morelli A, Iorio Small intestinal bacterial overgrowth and warfarin dose requirement variabilità Thromb Res 2010 488. Ambrogini P, Minelli A, Floridi A, Lattanzi D, Ciuffoli S, Bucherelli C, Prospero E, Frontini A, Santarelli L, Baldi E, Benetti F, Galli F, Cuppini R. Maternal dietary loads of alpha-­‐tocopherol depress protein kinase c (PKC) signaling and synaptic plasticity in rat postnatal developing hippocampus and promote permanent deficits in adult offspring J Nutr Biochem 2010 489. Piroddi M, Palazzetti I, Quintaliani G, Pilolli F, Libetta C, Galli F. Circulating levels and dietary intake of the AGE marker carboxymethyl-­‐lysine in chronic renal failure patients on conservative pre-­‐dialysis therapy: a pilot study. J, Renal Nutr. 2010 490. Piroddi M, Palmese A, Pilolli F, Amoresano A, Pucci P, Ronco C, Galli F. Plasma nitroproteome of kidney disease patients . Amino Acids. 2010 491. Galli F. On the antiatherogenic effects of vitamin E: the search for the Holy Grail. Vasc Health Risk Manag. 2010 492. Galli F, Iuliano L, Do statins cause myopathy by lowering vitamin E levels. Med Hypotheses 2010 493. Galli F, Azzi, A, Present trends in vitamin E. Biofactors. 2010 494. Brigelius-­‐Flohé R, Galli F, Vitamin E: a vitamin still awaiting the detection of its biological function. Mol Nutr Food Res. 2010 495. Galli F Amino acid and protein modification by reactive oxygen and nitrogen species, Amino Acids. 2010 496. Luchetti F, Canonico B, Betti M, Arcangeletti M, Pilolli F, Piroddi M, Canesi L, Papa S, Galli F. Melatonin signaling and cell protection function. FASEB J. 2010 497. Galli F. Meeting report: Vitamin E Satellite Symposium (VESS) associated to the Annual Meeting of the SFRR-­‐Europe. Free Rad. Res. 2010 35 498. Fusaro M, Noale M, Viola V, Galli F, Tripepi G, Vajente N, Plebani M, Zaninotto M, Guglielmi G, Miotto D, Dalle Carbonare L, D'Angelo A, Naso A, Grimaldi C, Miozzo D, Giannini S, Gallieni .Vitamin K, vertebral fractures, vascular calcifications, and mortality: VItamin K . alian (VIKI) dialysis study.. J Bone Miner Res. 2010 499. Sultana R, Piroddi M, Galli F, Butterfield DA Protein Levels and Activity of Some Antioxidant Enzymes in Hippocampus of Subjects with Amnestic Mild Cognitive Impairment Neurochem Res 2008 500. Mazzini F, Betti M, Netscher Th, Galli F, Salvadori P, Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds Chirality 2009 501. Luchetti F, Betti M, Canonico B, Arcangeletti M, Ferri P, Galli F, Papa S ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-­‐stressed U937 cells Free Radic Biol Med 2009 502. Iuliano L, Monticolo R, Straface G, Zullo S, Galli F, Boaz M, Quattrucci S . Association of cholesterol oxidation and abnormalities in fatty acid metabolism in cystic fibrosis Am J Clin Nutr 2009 503. Floridi A, Piroddi M, Pilolli F, Matsumoto Y, Aritomi M, Galli F, Analysis method and characterization of the antioxidant capacity of vitamin E-­‐interactive polysulfone hemodialyzers Acta Biomater 2009 504. Chiappetta G, Corbo C, Palmese A, Galli F, Piroddi M, Marino G, Amoresano A Quantitative identification of protein nitration sites Proteomic. 2009 505. Varga Z, Kosaras E, Komodi E, Katko M, Karpati I, Balla J, Paragh G, Aisa MC, Galli F, Effects of tocopherols and 2,2'-­‐carboxyethyl hydroxychromans on phorbol-­‐ester-­‐stimulated neutrophils J Nutr Biochem 2008 506. Minelli A, Bellezza I, Grottelli S, Galli F. Focus on cyclo(His-­‐Pro): history and perspectives as antioxidant peptide Amino Acids 2008 507. Bader Lange ML, Cenini G, Piroddi M, Abdul HM, Sultana R, Galli F, Memo M, Butterfield DA Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease Neurobiol Dis 2008 Gammaitoni Luca 508. I Neri, F Travasso, R Mincigrucci, H Vocca, F Orfei, L Gammaitoni. A real vibration database for kinetic energy harvesting application. Journal of Intelligent Material Systems and Structures. 2012 509. Helios Vocca, Igor Neri, Flavio Travasso, Luca Gammaitoni. A real vibration database for kinetic energy harvesting application, Journal of Intelligent Material Systems and Structures. 2012 510. L. Gammaitoni. There's plenty of energy at the bottom (micro and nano scale nonlinear noise harvesting). Contemporary Physics. 2012 511. F Cottone, L Gammaitoni, H Vocca, M Ferrari, V Ferrari. Piezoelectric buckled beams for random vibration energy harvesting. Smart materials and structures. 2012 512. L Gammaitoni. 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Physical Review Letters. 2011 516. M López-­‐Suárez, R Rurali, L Gammaitoni, G Abadal. Nanostructured graphene for energy harvesting. Physical Review B.2011 517. F Hartmann, L Gammaitoni, S Hofling, A Forchel, L Worschech. Nanowatt logic stochastic resonance in branched resonant tunneling diodes. Applied Physics Letters. 2011 518. L Gammaitoni, I Neri, H Vocca. The benefits of noise and nonlinearity: Extracting energy from random vibrations. Chemical Physics. 2010 519. F Hartmann, D Hartmann, P Kowalzik, A Forchel, L Gammaitoni, L Worschech. Stochastic resonance in a nanoscale Y-­‐branch switch. Applied Physics Letters. 2010 520. F Hartmann, D Hartmann, P Kowalzik, L Gammaitoni, A Forchel, L Worschech. Nonlinear sensors: An approach to the residence time detection strategy. Physical Review E.2010 521. A Dari, L Bosi, L Gammaitoni. Nonlinear sensors: An approach to the residence time detection strategy. Physical Review E. 2010 522. L Worschech, F Hartmann, TY Kim, S Hofling, M Kamp, A Forchel, J Ahopelto, I Neri, A Dari, L Gammaitoni. Universal and reconfigurable logic gates in a compact three-­‐terminal resonant tunneling diode. Applied Physics Letters. 2010 523. A Dari, F Travasso, H Vocca, L Gammaitoni. Breaking strength tests on silicon and sapphire bondings for gravitational wave detectors. Classical and Quantum Gravity. 2010 524. B Andò, S Baglio, M Ferrari, V Ferrari, L Gammaitoni, C Trigona. Nonlinear Dynamics, Materials and Integrated Devices for Energy Harvesting in Wearable Sensors. Wearable and Autonomous Biomedical Devices and Systems for Smart Environment 2010 525. F Acernese, M Alshourbagy, P Amico, F Antonucci, S Aoudia, KG Arun, P Astone, S Avino, L Baggio, G Ballardin, F Barone, L Barsotti, M Barsuglia, Th S Bauer, S Bigotta, S Birindelli, MA Bizouard, C Boccara, F Bondu, L Bosi, S Braccini, C Bradaschia, A Brillet, V Brisson, D Buskulic, G Cagnoli, E Calloni, E Campagna, F Carbognani, F Cavalier, R Cavalieri, G Cella, E Cesarini, E Chassande-­‐Mottin, S Chatterji, F Cleva, E Coccia, C Corda, A Corsi, F Cottone, JP Coulon, E Cuoco, S D'Antonio, A Dari, V Dattilo, M Davier, R De Rosa, M Del Prete, L Di Fiore, A Di Lieto, M Di Paolo Emilio, A Di Virgilio, V Fafone, I Ferrante, F Fidecaro, I Fiori, R Flaminio, JD Fournier, S Frasca, F Frasconi, L Gammaitoni, F Garufi, E Genin, A Gennai, A Giazotto, V Granata, C Greverie, D Grosjean, G Guidi, S Hamdani, S Hebri, H Heitmann, P Hello, D Huet, P La Penna, M Laval, N Leroy, N Letendre, B Lopez, M Lorenzini, V Loriette, G Losurdo, JM Mackowski, E Majorana, N Man, M Mantovani, F Marchesoni, F Marion, J Marque, F Martelli, A Masserot, F Menzinger, C 37 Michel, L Milano, Y Minenkov, S Mitra, Julien Moreau, N Morgado, S Mosca, B Mours, I Neri, F Nocera, G Pagliaroli, C Palomba, F Paoletti, S Pardi, A Pasqualetti, R Passaquieti, D Passuello, F Piergiovanni, L Pinard, R Poggiani, M Punturo, P Puppo, O Rabaste, P Rapagnani, T Regimbau, F Ricci, I Ricciardi, A Rocchi, L Rolland, R Romano, P Ruggi, D Sentenac, S Solimeno, BL Swinkels, R Terenzi, A Toncelli, M Tonelli, E Tournefier, F Travasso, G Vajente, JFJ van den Brand, S van der Putten, D Verkindt, F Vetrano, A Viceré, JY Vinet, H Vocca, M Yvert. 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Astrophysically triggered searches for gravitational waves: status and prospects. Classical and Quantum Gravity. 2008 Gerli Roberto 534. Alunno A, Nocentini G, Bistoni O, Petrillo MG, Bartoloni Bocci E, Ronchetti S, Lo Vaglio E, Riccardi C, Gerli R. Expansion of CD4+CD25-­‐GITR+ regulatory T-­‐cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity. Reumatismo. 2012 Dec 11;64(5):293-­‐8 535. Tavoni AG, Baldini C, Bencivelli W, Cavazzini L, Covelli M, De Vita S, Caporali R, Gerli R, Giansanti M, Govoni M, Donati V, Montecucco CM, Morbini P, Pilato FP, Resta L, Scott CA, Mosca M, Vitali C, Bombardieri S; Italian Study Group on Sjögren's Syndrome of the Italian Society of Rheumatology. Minor salivary gland biopsy and Sjögren's syndrome: comparative analysis of biopsies among different Italian rheumatologic centers. Clin Exp Rheumatol. 2012 Nov-­‐Dec;30(6):929-­‐33 536. Bartoloni E, Alunno A, Santoboni G, Gerli R. Beneficial cardiovascular effects of low-­‐dose glucocorticoid therapy in inflammatory rheumatic diseases. J Rheumatol. 2012 Aug;39(8):1758-­‐60 537. Atzeni F, Sarzi-­‐Puttini P, Botsios C, Carletto A, Cipriani P, Favalli EG, Frati E, Foschi V, Gasparini S, Giardina A, Gremese E, Iannone F, Sebastiani M, Ziglioli T, Biasi D, Ferri C, Galeazzi M, Gerli R, Giacomelli R, Gorla R, Govoni M, Lapadula G, Marchesoni A, Salaffi F, Punzi L, Triolo G, Ferraccioli G. Long-­‐term anti-­‐TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registry. Autoimmun Rev. 2012 Dec;12(2):225-­‐9 538. Alunno A, Bartoloni E, Bistoni O, Nocentini G, Ronchetti S, Caterbi S, Valentini V, Riccardi C, Gerli R. Balance between regulatory T and Th17 cells in systemic lupus erythematosus: the old and the new. Clin Dev Immunol. 2012; 2012: 823085. 539. Bartoloni E, Alunno A, Gerli R. Primary Sjögren's syndrome as paraneoplastic disorder: a case report. Clin Exp Rheumatol. 2012 May-­‐Jun;30(3):454 540. Iannone F, Gremese E, Atzeni F, Biasi D, Botsios C, Cipriani P, Ferri C, Foschi V, Galeazzi M, Gerli R, Giardina A, Marchesoni A, Salaffi F, Ziglioli T, Lapadula G; Gruppo Italiano di Studio sulle Early Arthritides (GISEA). Longterm retention of tumor necrosis factor-­‐α inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors. J Rheumatol. 2012;39(6):1179-­‐84 541. Bartoloni E, Alunno A, Bistoni O, Bizzaro N, Migliorini P, Morozzi G, Doria A, Mathieu A, Lotzniker M, Allegri F, Riccieri V, Alpini C, Gabrielli A, Tampoia M, Gerli R; Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA) investigators. Diagnostic value of anti-­‐mutated citrullinated vimentin in comparison to anti-­‐cyclic citrullinated peptide and anti-­‐viral citrullinated peptide 2 antibodies in rheumatoid arthritis: an Italian multicentric study and review of the literature. Autoimmun Rev. 2012;11(11):815-­‐20. 542. Schillaci G, Bartoloni E, Pucci G, Pirro M, Settimi L, Alunno A, Gerli R, Mannarino E. Aortic stiffness is increased in polymyalgia rheumatica and improves after steroid treatment. Ann Rheum Dis. 2012 ;71(7):1151-­‐6. 543. Pirro M, Bocci EB, Di Filippo F, Schillaci G, Mannarino MR, Bagaglia F, Gerli R, Mannarino E.Imbalance between endothelial injury and repair in patients with polymyalgia rheumatica: improvement with corticosteroid treatment. J Intern Med. 2012;272(2):177-­‐84 544. Gutierrez M, Luccioli F, Salaffi F, Bartoloni E, Bertolazzi C, Bini V, Filipucci E, Grassi W, Gerli R. Ultrasound revealing subclinical enthesopathy at the greater trochanter level in patients with spondyloarthritis. Clin Rheumatol. 2012;31(3):463-­‐8. 545. Lapadula G, Ferraccioli G, Ferri C, Punzi L, Trotta F; GISEA. GISEA: an Italian biological agents registry in rheumatology. Reumatismo. 2011;63(3):155-­‐64 546. Bizzaro N, Allegri F, Alpini C, Doria A, Gerli R, Lotzniker M, Mathieu A, Morozzi G, Bellisai F, Riccieri V, Tampoia M, Migliorini P. Multicentric evaluation of a second generation assay to detect antiviral citrullinated peptide antibodies: a collaborative study by the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni. J Clin Pathol. 2011 Dec;64(12):1139-­‐41 39 547. Pauer L, Winkelmann A, Arsenault P, Jespersen A, Whelan L, Atkinson G, Leon T, Zeiher B; A0081100 Investigators. An international, randomized, double-­‐blind, placebo-­‐controlled, phase III trial of pregabalin monotherapy in treatment of patients with fibromyalgia. J Rheumatol. 2011;38(12):2643-­‐52 548. Bartoloni E, Ludovini V, Alunno A, Pistola L, Bistoni O, Crinò L, Gerli R.Increased levels of circulating DNA in patients with systemic autoimmune diseases: A possible marker of disease activity in Sjögren's syndrome. Lupus. 2011;20(9):928-­‐35. 549. Bianchini R, Bistoni O, Alunno A, Petrillo MG, Ronchetti S, Sportoletti P, Bocci EB, Nocentini G, Gerli R, Riccardi C. CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-­‐cell population with regulatory activity. Eur J Immunol. 2011 Aug;41(8):2269-­‐78 550. Moscatelli S, Simonetti S, Bartoloni Bocci E, Gerli R. Unusual subcutaneous swellings on the hand as primary presenting feature of sarcoidosis.J Rheumatol. 2011 r;38(3):519-­‐21. 551. Ghirardello A, Villalta D, Morozzi G, Afeltra A, Galeazzi M, Gerli R, Mathieu A, Meroni PL, Pregnolato F, Migliorini P, Radice A, Riccieri V, Ruffatti A, Sebastiani GD, Sinico RA, Tincani A, Doria A; Forum Interdisciplinare per la Ricerca sulle Malattie Autoimmuni(FIRMA) study group. Diagnostic accuracy of currently available anti-­‐double-­‐stranded DNA antibody assays. An Italian multicentre study. Clin Exp Rheumatol. 2011 Jan-­‐Feb;29(1):50-­‐6. 552. Costa S, Mondini M, Caneparo V, Afeltra A, Airò P, Bellisai F, Faggioli P, Gerli R, Lotzniker M, Meroni PL, Morozzi G, Radice A, Riccieri V, Scarsi M, Sebastiani GD, Sinico RA, Tincani A, Gariglio M, Landolfo S. Detection of anti-­‐IFI16 antibodies by ELISA: clinical and serological associations in systemic sclerosis. Rheumatology (Oxford). 2011 Apr;50(4):674-­‐81 553. Dejaco C, Duftner C, Cimmino MA, Dasgupta B, Salvarani C, Crowson CS, Maradit-­‐Kremers H, Hutchings A, Matteson EL, Schirmer M; International Work Group for PMR and GCA. Definition of remission and relapse in polymyalgia rheumatica: data from a literature search compared with a Delphi-­‐based expert consensus. Ann Rheum Dis. 2011 Mar;70(3):447-­‐53 554. Alunno A, Nocentini G, Bistoni O, Bianchini R, Bartoloni Bocci E, Riccardi C, Gerli R. [Glucocorticoid induced TNFR-­‐related protein (GITR) as marker of human regulatory T cells: expansion of the GITR(+)CD25⁻ cell subset in patients with systemic lupus erythematosus]. Reumatismo. 2010 Jul-­‐Sep;62(3):195-­‐201 555. Bartoloni E, Shoenfeld Y, Gerli R. Inflammatory and autoimmune mechanisms in the induction of atherosclerotic damage in systemic rheumatic diseases: two faces of the same coin. Arthritis Care Res (Hoboken). 2011 Feb;63(2):178-­‐83. 556. Bartoloni E, Alunno A, Luccioli F, Moscatelli S, Biscontini D, Santoboni G, Gerli R. Atherosclerotic vascular damage and rheumatoid arthritis: a complex but intriguing link. Expert Rev Cardiovasc Ther. 2010 Sep;8(9):1309-­‐16 557. Sarzi-­‐Puttini P, Atzeni F, Gerli R, Bartoloni E, Doria A, Barskova T, Matucci-­‐Cerinic M, Sitia S, Tomasoni L, Turiel M. Cardiac involvement in systemic rheumatic diseases: An update. Autoimmun Rev. 2010 Oct;9(12):849-­‐52 558. Bartoloni E, Alunno A, Bistoni O, Gerli RHow early is the atherosclerotic risk in rheumatoid arthritis? Autoimmun Rev. 2010 Aug;9(10):701-­‐7. 559. Gerli R, Bocci EB, Shoenfeld Y. Association of subclinical atherosclerosis and leukopenia in systemic autoimmune diseases: comment on the article by Huang et al. Arthritis Rheum. 2010 Sep;62(9):2823-­‐4 560. Gerli R, Secciani I, Sozio F, Rossi A, Weber E, Lorenzini G. Absence of lymphatic vessels in human dental pulp: a morphological study. Eur J Oral Sci. 2010 Apr;118(2):110-­‐7. 561. Iaccheri B, Androudi S, Bocci EB, Gerli R, Cagini C, Fiore T. Rituximab treatment for persistent scleritis associated with rheumatoid arthritis. Ocul Immunol Inflamm. 2010 Jun;18(3):223-­‐5 562. Seror R, Mariette X, Bowman S, Baron G, Gottenberg JE, Boostma H, Theander E, Tzioufas A, Vitali C, Ravaud P; European League Against Rheumatism Sjögren's Task Force. Accurate detection of changes in disease activity in primary Sjögren's syndrome by the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index. Arthritis Care Res (Hoboken). 2010 Apr;62(4):551-­‐8 563. Gerli R, Vaudo G, Bocci EB, Schillaci G, Alunno A, Luccioli F, Hijazi R, Mannarino E, Shoenfeld Y.Functional impairment of the arterial wall in primary Sjögren's syndrome: combined action of immunologic and inflammatory factors. Arthritis Care Res (Hoboken). 2010 May;62(5):712-­‐8 564. Scarpato S, Antivalle M, Favalli EG, Nacci F, Frigelli S, Bartoli F, Bazzichi L, Minisola G, Matucci Cerinic M; RIVIERA co-­‐authors. Patient preferences in the choice of anti-­‐TNF therapies in rheumatoid arthritis. Results from a questionnaire survey (RIVIERA study). Rheumatology (Oxford). 2010 Feb;49(2):289-­‐94. 565. Meron MK, Amital H, Shepshelovich D, Barzilai O, Ram M, Anaya JM, Gerli R, Nicola B, Shoenfeld Y. Infectious aspects and the etiopathogenesis of rheumatoid arthritis. Clin Rev Allergy Immunol. 2010 Apr;38(2-­‐3):287-­‐91. 40 566. Seror R, Ravaud P, Bowman SJ, Baron G, Tzioufas A, Theander E, Gottenberg JE, Bootsma H, Mariette X, Vitali C; EULAR Sjögren's Task Force. EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome.Ann Rheum Dis. 2010; 69(6):1103-­‐9. 567. Bartoloni E, Alunno A, Luccioli F, Santoboni G, Gerli R.Successful treatment of refractory adult-­‐onset Still's disease with anti-­‐CD20 monoclonal antibody. Clin Exp Rheumatol. 2009 Sep-­‐Oct;27(5):888-­‐9 568. Bocci EB, Biscontini D, Olivieri I, Gerli R. Acro-­‐osteolysis of the big toe in a patient with psoriatic arthritis. J Rheumatol. 2009; 36(9):2044. 569. Bartoloni Bocci E, Giordano A, Luccioli F, Alunno A, Gerli R. Crescentic glomerulonephritis and circulating antineutrophil cytoplasmic antibodies in scleroderma: a case report and review of the literature. Clin Exp Rheumatol. 2009 Mar-­‐Apr;27(2):385-­‐6. 570. Biscontini D, Bartoloni Bocci E, Gerli R. [Analysis of foot structural damage in rheumatoid arthritis: clinical evaluation by validated measures and serological correlations]. Reumatismo. 2009 Jan-­‐Mar;61(1):48-­‐53. Italian 571. Gerli R, Nocentini G, Alunno A, Bocci EB, Bianchini R, Bistoni O, Riccardi C. Identification of regulatory T cells in systemic lupus erythematosus. Autoimmun Rev. 2009;8(5):426-­‐30. 572. Tinazzi E, Puccetti A, Gerli R, Rigo A, Migliorini P, Simeoni S, Beri R, Dolcino M, Martinelli N, Corrocher R, Lunardi C.Serum DNase I, soluble Fas/FasL levels and cell surface Fas expression in patients with SLE: a possible explanation for the lack of efficacy of hrDNase I treatment. Int Immunol. 2009 Mar;21(3):237-­‐43. 573. Gerli R, Vaudo G, Bocci EB, Schillaci G, Bistoni O, Shoenfeld Y.Different roles for anti-­‐cyclic citrullinated peptide antibodies and CD4+CD28null cells in the acceleration of atherosclerosis in rheumatoid arthritis: comment on the article by Farragher et al. Arthritis Rheum.2009 574. Rossi A, Pasqui D, Barbucci R, Gerli R, Weber E. The topography of microstructured surfaces differently affects fibrillin deposition by blood and lymphatic endothelial cells in culture. Tissue Eng Part A. 2009;15(3):525-­‐33. 575. Frallonardo P, Ramonda R, Salaffi F, Carotti M, Andretta M, Zucchetta P, Dorigo A, Campana C, Contessa C, Iagnocco A, Valesini G, Gerli R, Grassi W, Punzi L. [Sjögren's syndrome: comparison among the main imaging techniques in the study of major salivary glands]. Reumatismo. 2008;60(2):141-­‐9. Italian. 576. Cimmino MA, Salvarani C, Macchioni P, Gerli R, Bartoloni Bocci E, Montecucco C, Caporali R; Systemic Vasculitis Study Group of the Italian Society for Rheumatology. Long-­‐term follow-­‐up of polymyalgia rheumatica patients treated with methotrexate and steroids. Clin Exp Rheumatol. 2008 May-­‐
Jun;26(3):395-­‐400 577. Salaffi F, Carotti M, Iagnocco A, Luccioli F, Ramonda R, Sabatini E, De Nicola M, Maggi M, Priori R, Valesini G, Gerli R, Punzi L, Giuseppetti GM, Salvolini U, Grassi W. Ultrasonography of salivary glands in primary Sjögren's syndrome: a comparison with contrast sialography and scintigraphy.Rheumatology (Oxford). 2008;47(8):1244-­‐9. 578. Gerli R, Bartoloni Bocci E, Sherer Y, Vaudo G, Moscatelli S, Shoenfeld Y. Association of anti-­‐cyclic citrullinated peptide antibodies with subclinical atherosclerosis in patients with rheumatoid arthritis. Ann Rheum Dis. 2008 May;67(5):724-­‐5. 579. Lorenzi B, Pessina F, Lorenzoni P, Urbani S, Vernillo R, Sgaragli G, Gerli R, Mazzanti B, Bosi A, Saccardi R, Lorenzi M. Treatment of experimental injury of anal sphincters with primary surgical repair and injection of bone marrow-­‐derived mesenchymal stem cells. Dis Colon Rectum. 2008 Apr;51(4):411-­‐20 580. Gerli R, Lunardi C, Bocci EB, Bobbio-­‐Pallavicini F, Schillaci G, Caporali R, Bistoni O, Pirro M, Pitzalis C, Montecucco C. Anti-­‐tumor necrosis factor-­‐alpha response in rheumatoid arthritis is associated with an increase in serum soluble CD30. J Rheumatol. 2008 Jan;35(1):14-­‐9. Germani Raimondo 581. Marta Bettoni, Lucia Brinchi, Tiziana Del Giacco, Raimondo Germani, Sara Maniconi, Cesare Rol, Giovanni Vittorio Sebastiani,“Surfactant Effect on Titanium Dioxide Photosensitized Oxidation of 4-­‐dodecyloxybenzyl alcohol” J. Photochem. Photobiol. A: Chemistry, 2012; 229 (1), 53-­‐59. 582. Valerio De Santi, Fabio Cardellini, Lucia Brinchi, Raimondo Germani, “Novel Brønsted acidic deep eutectic solvents as reaction media for esterification of carboxylic acids with alcohols” Tetrahedron Letters, 2012; 53 (38) 5151-­‐5155. 583. Alessandro Sorrenti, Barbara Altieri, Francesca Ceccacci, Pietro Di Profio, Raimondo Germani, Luisa Giansanti, Gianfranco Savelli, Giovanna Mancini,“Deracemization of bilirubin as the markerof the chirality of micellar aggregates” Chirality, 2012, 24 (1), 78-­‐85. 584. R. Germani, M.V. Mancini, N. Spreti, P. Di Profio, G. Savelli,“Cu(II) Extraction in Ionic Liquids and 41 Chlorinated Solvents: Temperature Effect”Green and Sustainable Chemistry, 2011; 1 (4), 155-­‐164. 585. Di Crescenzo, R. Germani, E. Del Canto, S. Giordani, G. Savelli, A. Fontana, “Effect of surfactant structure on carbon nanotube sidewalls adsorption”Eur. J. Org. Chem., 2011, 2011, (28) 5641-­‐5648. 586. F. Cuomo, A. Ceglie, G. Colafemmina, R. Germani, G. Savelli, F. Lopez “Polyadenylic acid binding on cationic liposomes doped with the non-­‐ionic nucleolipid Lauroyl Uridine”Colloid and Surfaces B: Biointerfaces, 2011, 82 (2), 277-­‐282. 587. Di Michele, L. Brinchi, P. Di Profio, R. Germani, G. Savelli, G. Onori,“Effect of Head-­‐Group Size, Temperature and Counter Ion Specificity on Cationic Micelles”J. Colloid Interface Sci., 2011, 358 (1), 160-­‐
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nitrobenzisoxazole-­‐3-­‐carboxylate in imidazolium-­‐based ionic liquids and surfactant ionic liquids” J. Colloid Interface Sci. 2010, 348(1) 137-­‐145 592. L. Brinchi, R. Germani, G. Savelli, A. Di Michele, G. Onori, “Premicelles of cetyltrimethyl -­‐ammonium methanesulfonate: Spectroscopic and kinetic evidence”Colloids and Surfaces A: Physicochem. Eng. Aspects,. 2009, 336(1-­‐2), 75-­‐78. 593. L. Brinchi, L. Chiavini, L. Goracci, P. Di Profio, R. Germani “Efficient Hydrolysis of Nitriles to Amides with Hydroperoxide Anion in Aqueous Surfactant Solutions as Reaction Medium” Lett. Organic Chem., 2009, 6(2), 175-­‐179. 594. P. Baglioni, E. Braccalenti, E. Carretti, R. Germani, L. Goracci, G. Savelli, M. Tiecco “Surfactant-­‐Based Photorheological Fluids: Effect of the Surfactant Structure” Langmuir 2009, 25(10), 5467-­‐5475. 595. M. Tiecco, R. Germani, P. Di Profio, G. Savelli, "Synthesis of Novel 5’ Uridine-­‐Head Amphiphiles as Models for DNA Molecular Recognition", Nucleosides, Nucleotides & Nucleic Acids, 2009, 28 (10), 911-­‐923. 596. N. Spreti, M.V. Mancini, R. Germani, P.Di Profio, G. Savelli “Substrate Effect on Chymotrypsin Activity in Aqueous Solutions of “Big Head” Ammonium Salts”, J. Molecular Catalysis, B: Enzymatic, 2008; 50(1), 1-­‐6. 597. F.P. Ballistreri, L. Brinchi, R. Germani, G. Savelli, G.A. Tomaselli, R.M. Toscano ”Enantioselective Epoxidation of Alkenes Catalized by (Salen)Mn(III) in Aqueous Surfactant Systems” Tetrahedron. 2008, 64 (44), 10239-­‐10243 Gigliotti Giovanni 598. Pezzolla D., Bol R., Gigliotti G., Sawamoto T., Louro López A., Cardenas L., Chadwick D. Greenhouse gas (GHG) emissions from soils amended with digestate derived from anaerobic treatment of food waste. Rapid communications in mass spectrometry. 26, 2422-­‐2430, 2012. 599. Gigliotti G., Proietti P., Said-­‐Pullicino D., Nasini L., Pezzolla D., Rosati L., Porceddu P.R. Co-­‐composting of olive husks with high moisture contents: organic matter dynamics and compost quality. International Biodeterioration and Biodegradation. 67, 8-­‐14, 2012. 600. Del Buono D., Said-­‐Pullicino D., Proietti P., Nasini L., Gigliotti G. Utilization of olive husks as plant growing substrates: phytotoxicity and plant biochemical responses. Compost Science and Utilization 19, 52-­‐60, 2011. 601. Traversa A., Said-­‐Pullicino D., D’Orazio V., Gigliotti G., Senesi N. Properties of humic acids in Mediterranean forest soils (Southern Italy): influence of different plant covering. European Journal of Forest Research 130, 1045-­‐1054, 2011. 602. Said-­‐Pullicino D., Massaccesi L., Dixon L., Bol R., Gigliotti G. Organic matter dynamics in a compost-­‐
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Benninghoff J, Gritti A, Rizzi M, Lamorte G, Schloesser RJ, Schmitt A, Robel S, Genius J, Moessner R, Riederer P, Manji HK, Grunze H, Rujescu D, Moeller HJ, Lesch KP, Vescovi AL. Serotonin Depletion Hampers Survival and Proliferation in Neurospheres Derived from Adult Neural Stem Cells. 43 Neuropsychopharmacology. 2010 Mar;35(4):893-­‐903. 623. Gritti A, Dal Molin M, Foroni C, Bonfanti L. Effects of developmental age, brain region and time in culture on long-­‐term proliferation and multipotency of neural stem cell populations. J Comp Neurol 2009, 517(3):333-­‐349 624. S Pluchino*, A Gritti*, E Blezer, S Amadio, E Brambilla, G Borsellino, C Cossetti, U Del Carro, G Comi, B ‘t Hart, A Vescovi, and G Martino. Human neural stem cells ameliorate autoimmune encephalomyelitis in non-­‐human primates. Annals of Neurology 2009, 66(3):343-­‐354.* co-­‐authorship 625. Visigalli I, Moresco RM, Belloli S, Politi LS, Gritti A, Ungaro D, Matarrese M, Turolla E, Falini A, Scotti G, Naldini L, Fazio F, Biffi A. Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195. Neurobiology of Disease 2009, 34(19): 51-­‐62. 626. Martino S, di Girolamo I, Cavazzin C, Tiribuzi R, Galli R, Rivaroli A, Valsecchi M, Sandhoff K, Sonnino S, Vescovi A, Gritti A* and Orlacchio A*. Neural precursor cell cultures from GM2-­‐gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology. J Neurochem. 2009 109(1):135-­‐47*co-­‐authorship. 627. Martino S, Tiribuzi R, Tortori A, Conti D, Visigalli I, Lattanzi A, Biffi A, Gritti A and Orlacchio A. Specific determination of β-­‐galactocerebrosidase activity via competitive inhibition of β-­‐galactosidase. Clin Chem. 2009, 55(3):541-­‐8. 628. 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Pastorini, F Photophysical properties of haloderivatives of angelicins J. Photochem. Photobiol. A: Chemistry, 198, 98–105, 2008 Marcotullio Carla 663. E. Cenci, F. Messina, E. Rossi, F. Epifano, M. C. Marcotullio. Antiviral Furanosesquiterpenes from Commiphora erythraea. Nat. Prod. Commun 2012 664. D. Fraternale, S. Sosa, D. Ricci, S. Genovese, F. Messina, S. Tomasini, F. Montanari, M. C. Marcotullio. Anti-­‐
inflammatory, antioxidant and antifungal furanosesquiterpenoids isolated from Commiphora erythraea (Ehrenb.) Engl. Resin. Fitoterapia.2011 665. F. Conforti, M. C. Marcotullio, F. Menichini, G. A Statti, L. Vannutelli, G. Burini, F. Menichini, M. Curini. The influence of collection zone on glucosinolates, polyphenols, flavonoids content and biological profiles of Capparis sicula ssp sicula. Food Sci. Technol. Int.2011 45 666. S. Genovese, F. Epifano, M.C. Marcotullio, C. Pelucchini, M. Curini. An alternative quinoline synthesis by via Friedländer reaction catalyzed by Yb(OTf .Tetrahedron Lett.2011 667. M.C. Bonito, C. Cicala, M.C. Marcotullio, F. Maione, N. Mascolo. Biological activity of bicyclic and tricyclic diterpenoids from Salvia species of immediate pharmacological and pharmaceutical interest. Nat. Prod. Commun.2011 668. M.C. Marcotullio, F. Messina, M. Curini, A. Macchiarulo, M. Cellanetti, D. Ricci, L. Giamperi, A. Bucchini, A. Minelli, A.L. Mierla, I. Bellezza. Protective effects of Commiphora erythraea resin constituents in cellular oxidative damage. Molecules. 2011 669. F. Epifano, M. Curini, M.C. Marcotullio, S. Genovese. Searching for novel cancer chemopreventive plants and their products: the genus Zanthoxylum. Curr. Drug Targets.2011 670. O. Rosati, M. Curini, M.C. Marcotullio, G. Oball-­‐Mond, C. Pelucchini, A. Procopio. Synthesis of 5-­‐Amino-­‐
1,10-­‐dihydro-­‐2H-­‐chromeno[3,4-­‐c]pyridine-­‐2,4-­‐(3H)-­‐diones from Coumarins and Cyanoacetamides under Basic Conditions. Synthesis 2010 671. S. Genovese, F. Epifano, G. Carlucci, M.C. Marcotullio, M. Curini, M. Locatelli. Quantification of 4’-­‐
geranyloxyferulic acid, a new natural colon cancer chemopreventive agent, by HPLC-­‐DAD in grapefruit skin extract. J. Pharm. Biomed. Analysis.2010 672. L. Menghini, F. Epifano, S. Genovese, M.C. Marcotullio, S. Sosa, A. Tubaro .Anti-­‐inflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (Guss.) Tammaro (Apiaceae). Phytotherapy Res.2010 673. F. Epifano, S. Sosa, A. Tubaro, M.C. Marcotullio, M. Curini, S. Genovese. Topical anti-­‐inflammatory activity of boropinic acid and its natural and semi-­‐synthetic derivatives.2010 674. M. C. Marcotullio, O. Rosati, M. Curini Virescenols: Sources, Structures and Chemistry Nat. Prod. Commun 2008 675. F. Epifano, S. Genovese, M.C. Marcotullio, M. Curini Chemistry and Pharmacology of Collinin, Active Principle of Zanthoxylum spp. Mini-­‐Reviews in Medicinal Chemistry 2008 676. M. C. Marcotullio, G. N. Oball-­‐Mond Mwankie, L. Cossignani, B. Tirillini, R. Pagiotti .Phytochemical Analysis and Antiradical Properties of Sarcodon imbricatus (L.:Fr) Karsten Nat. Prod. Commun 2008 677. M. Curini, S. Genovese, L. Menghini, M.C. Marcotullio, F. Epifano. Phytochemistry and pharmacology of Boronia pinnata Sm. Nat. Prod. Commun 2008 678. M. C. Marcotullio, C. Santi, G. N. Oball-­‐Mond Mwankie, M. Curini. Chemical Composition of the Essential Oil of Commiphora erythraea. Nat. Prod. Commun.2008 Martino Sabata 679. Martino S., D’Angelo F, Armentano I., Kenny J.M., Orlacchio A. (2012) Stem cell-­‐biomaterial interactions for regenerative medicine. Biotechnology Advance. 230(1):338-­‐51.2012 Corresponding author 680. Martino S., Tiribuzi R., D'Angelo F., Orlacchio A (2012) Advanced Tools of Regenerative Medicine for Neurodegenerative Diseases. Recent Patents on Regenerative Medicine 2, 3 2012 Corresponding author 681. Lizundia E., Sarasua J.R., D’angelo F., Orlacchio A., Martino S., Kenny J.M,Armentano I. Biocompatible Poly (L-­‐lactide) / MWCNT nanocomposites: morphological characterization, electrical properties and stem cell interaction. Macromolecular Bioscience. 12(7):870-­‐81.2012
682. D'Angelo F., Armentano I., Cacciotti I., Tiribuzi R., Quattrocelli M., Del Gaudio C., Fortunati E., Saino E., Caraffa A., Cerulli G.G., Visai L., Kenny J.M., Sampaolesi M., Bianco A., Martino S. and Orlacchio A. (2012) Tuning Multi/Pluri-­‐Potent Stem Cell Fate by Electrospun Poly(l-­‐lactic acid)-­‐Calcium-­‐Deficient Hydroxyapatite Nanocomposite Mats. Biomacromolecules. 13:1350-­‐60.2012 Co-­‐corresponding author 683. Santambrogio S., Ricca A., Maderna C., Ieraci A., Aureli M., Sonnino S., Kulik W., Aimar P., Bonfanti L., Martino S. and Gritti A. (2012) The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-­‐natal CNS development. Human Molecular Genetics. 21(21):4732-­‐50. 2012 684. Trojani A, Di Camillo B, Tedeschi A, Lodola M, Montesano S, Ricci F, Vismara E, Greco A, Veronese S, Orlacchio A, Martino S, Colombo C, Mura M, Nichelatti M, Colosimo A, Scarpati B, Montillo M, Morra E. Gene expression profiling identifies ARSD as a new marker of disease progression and the sphingolipid metabolism as a potential novel metabolism in chronic lymphocytic leukemia. Cancer Biomark. 2011-­‐2012;11(1):15-­‐28. 2012 46 685. Bianco A, Bozzo BM, Cacciotti I, Del Gaudio C, Armentano I., Dottori M, Dangelo F, Martino S., Orlacchio A, Kenny JM. Poly(L-­‐Lactic Acid)/Calcium-­‐Deficient Nanohydroxyapatite Electrospun Mats for Murine Bone Marrow Stem Cell Cultures (2011). Journal of Bioactive and Compatible Polymers; 26: 225-­‐241. 2011
686. Martino S., Tiribuzi R., Ceraci E., Makrypidi G., D'Angelo F., Di Girolamo I., Gritti A., Cusella de Angelis M.G., Papaccio G.P., Sampaolesi M., Berardi A.C., Datti A., Orlacchio A. (2011). Coordinated Involvement of Cathepsins S, D and Cystatin C in the Commitment of Hematopoietic Stem Cells to Dendritic Cells. The International Journal Of Biochemistry & Cell Biology; 43:775-­‐83 Co-­‐corresponding author
687. Tiribuzi R., Orlacchio A., Crispoltoni L., Maiotti M., Zampolini M., De Angelis M., Mecocci P., Cecchetti R., Bernardi G., Datti A., Martino S., Orlacchio A. Lysosomal Beta-­‐Galactosidase and Beta-­‐
Hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimer’s disease and type 2 Diabetes mellitus. Journal of Alzheimer's Disease, 2011;24(4):785-­‐97., 2011. , 688. Fortunati E., D’Angelo F., Martino S., Orlacchio A., Kennyh J.M. and Armentano I. Carbon nanotubes and silver nanoparticles for multifunctional conductive biopolymer composites.. Carbon, 49: 2370-­‐
2379. 2011 689. d'Aquino R., Tirino V., Desiderio V., Studer M., De Angelis G.C., Laino L., De Rosa A., Di Nucci D., Martino S., Paino F., Sampaolesi M., Papaccio G. Human neural crest-­‐derived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo. Eurpean Cell & Materia Journal, 21:304-­‐
16. 2011
690. Quattrocelli M., Palazzolo G., Agnolin I., Martino S., Bouché M., Anastasia L., Sampaolesi M. (2011) Synthetic sulfonyl-­‐hydrazone-­‐1 positively regulates cardiomyogenic microRNA expression and cardiomyocyte differentiation of induced pluripotent stem cells. Journal of Cell Biochemistry. Mar 28. doi: 10.1002/jcb.23118. 2011 691. Mattoli F., Tiribuzi R., D'Angelo F., di Girolamo I., Quattrocelli M., Montesano S., Crispoltoni L., Oikonomou V., Cusella De Angelis M.G., Marconi P., Orlacchio A., Sampaolesi M., Martino S. and Orlacchio A. (2011) Development of a New Tool for 3D Modeling for Regenerative Medicine. International Journal of Biomedical Imaging, 2011:236854.2011 Co-­‐corresponding authos
692. D’Angelo F., Tiribuzi R., Armentano I., Kenny J.M., Martino S. and Orlacchio A. Mechanotransduction: Tuning Stem Cells Fate. Journal Functional Biomaterial, 2(2), 67-­‐87. 2011 Co-­‐corresponding authos
693. Neri M, Ricca A, di Girolamo I, Alcala'-­‐Franco B, Cavazzin C, Orlacchio A, Martino S, Naldini L, Gritti A. Neural stem cell gene therapy ameliorates pathology and function in a mouse model of globoid cell leukodystrophy. Stem Cells. 2011 Oct;29(10):1559-­‐71 694. Tiribuzi R, D'Angelo F, Berardi AC, Martino S and Orlacchio A. Knock-­‐down of HEXA and HEXB genes correlate with the absence of the immunostimulatory function of HSC-­‐derived dendritic cells. Cell Biochemistry and Function. 2011 Oct 13. doi: 10.1002/cbf.1819. Co-­‐corresponding authos
695. Orlacchio A., Bernardi G., Orlacchio A., Martino S. (2010) Stem Cells: An Overview of the Current Status of Therapies for Central and Peripheral Nervous System Diseases. Current Medicinal Chemistry. 17:595-­‐608. 2010
696. Lattanzi A., Neri M., Maderna C., di Girolamo I., Martino S., Orlacchio A., Amendola M., Naldini L., Gritti A. (2010) Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in Leukodystrophy mouse models. Human Molecular Genetics. 19:2208-­‐
27.2010
697. Orlacchio A., Bernardi G., Orlacchio A., Martino S. (2010) Stem cells and neurological diseases. Discovery Medicine; 9:546-­‐53. Review.2010
698. Visigalli I., Ungari S., Martino S., Park H., Cesani M., Gentner B., Sergi Sergi L., Orlacchio A, Naldini L, Biffi A. (2010). The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche. Blood. 116:1857-­‐66. 2010 699. D'Angelo F, Armentano I, Mattioli S, Crispoltoni L, Tiribuzi R, Cerulli GG, Palmerini CA, Kenny J.M., Martino S. and Orlacchio A. (2010) Micropatterned hydrogenated amorphous carbon guides mesenchymal stem cells towards neuronal differentiation. Eurpean Cell & Materia Journal. 20:231-­‐
44. 2010 Co-­‐corresponding authos
700. Gentner B., Visigalli I., Hiramatsu H., Lechman E., Ungari S., Giustacchini A., Schira G., Amendola M., Quattrini A., Martino S., Orlacchio A., Dick J.E., Biffi A., Naldini L. (2010) Identification of hematopoietic stem cell-­‐specific miRNAs enables gene therapy of globoid cell leukodystrophy. Science Translational Medicine; 2: 58ra84. 2010
47 701. Martino S., Tiribuzi R., Tortori A., Conti D., Visigalli I., Lattanti A., Biffi A., Gritti A. and Aldo Orlacchio (2009) Specific determination of b-­‐galactocerebrosidase activity via competitive inhibition of b-­‐
galactosidase. Clinical Chemistry. 55:541-­‐548. 2009
702. Martino S., Gritti A., di Girolamo I., Cavazzini C., Tiribuzi R., Galli R., Sandhoff K, Vescovi A., Aldo Orlacchio (2009) Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology. Journal of Neurochemistry. 109: 135-­‐147. 2009 703. Martino S., di Girolamo I., Tiribuzi R., D'Angelo F., Datti A., Orlacchio A. (2009) Efficient siRNA Delivery by the Cationic Liposome DOTAP in Human Hematopoietic Stem Cells Differentiating into Dendritic Cells, Journal of Biomedicine and Biotechnology. doi: 10.1155/2009/410260 2009
704. Martino S., D'Angelo F., Armentano I., Tiribuzi R., Pennacchi E., Dottori M., Mattioli S., Caraffa A. Cerulli G. Kenny J.M., Orlacchio A. (2009) a-­‐C:H nanopatterned film designs drive human bone marrow mesenchymal stem cell cytoskeleton architecture. Tissue engineering. Part A. 15:3139-­‐49. 2009
705. Martino S., di Girolamo I., Orlacchio A., Datti A., Orlacchio A. MicroRNA implications across neurodevelopment and neuropathology. Journal of Biomedicine and Biotechnology. 2009:654346. Review. 2009
706. Balducci C., Bibi L., Berg T., Persichetti E., Tiribuzi R., Martino S., Paciotti S., Roberti R., Orlacchio A., Beccari T. (2008). Molecular cloning and structural organization of the gene encoding the mouse lysosomal di-­‐N-­‐acetylchitiobiase (cbs). Gene, 1-­‐2, 416: 85-­‐91. 2008
707. Tiribuzi R., Martino S., Ciraci E., D’Angelo F., di Girolamo I., Datti A. Bottazzo GF., Berardi A.C. and Orlacchio A. (2008) Non-­‐redundant roles of Cathepsin L, Cathepsin B and Cathepsin S in +
CD1a Dendritic Cells knocked-­‐down for Cathepsin S by RNA interference. Minerva Biotecnologica. 20: 59-­‐67. 2008
708. Orlacchio An., Bernardi G., Orlacchio A., Martino S. Patented therapeutic RNAi strategies for neurodegenerative diseases of the CNS. Expert Opinion on Therapeutic Patents. 18:1161-­‐117. 2008
Mecocci Patrizia 709. Spulber G, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Lovestone S, Wahlund LO, Westman E; The AddNeuroMed consortium for the Alzheimer Disease Neuroimaging Initiative. An MRI-­‐based index to measure the severity of Alzheimer’s disease-­‐like structural pattern in subjects with mild cognitive impairment .JOURNAL OF INTERNAL MEDICINE.2012 710. Greco I, Day N, Riddoch-­‐Contreras J, Reed J, Soininen H, K 322 Oszewska I, Tsolaki M, Vellas B, Spenger C, Mecocci P, Wahlund LO, Simmons A, Barnes J, Lovestone SS. Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation JOURNAL OF TRANSLATIONAL MED.2012 711. Velayudhan L, Proitsi P, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Hodges A, Powell J, Lovestone S, Simmons A . Entorhinal Cortex Thickness Predicts Cognitive Decline in Alzheimer's Disease. JOURNAL OF ALZHEIMER .2012 712. Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, Lovestone S, Dobson R, Hodges A .A Blood Gene Expression Marker of Early Alzheimer's Disease. JOURNAL OF ALZHEIMER DISEASE.2012 713. Kiddle SJ, Thambisetty M, Simmons A, Riddoch-­‐Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Mecocci P, Lovestone S, Newhouse S, Dobson R; for the Alzheimers Disease Neuroimaging Initiative . Plasma Based Markers of [(11)C] PiB-­‐PET Brain Amyloid Burden. PLoS One 2012 714. Cocciolo A, Di Domenico F, Coccia R, Fiorini A, Cai J, Pierce WM, Mecocci P, Butterfield DA, Perluigi M. Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics. FREE RADICAL BIOLOGY & MEDICINE 2012 715. Polidori MC, Pientka L, Mecocci P. A review of the major vascular risk factors related to Alzheimer's disease JOURNAL OF ALZHEIMER DISEASE 2012 716. Di Domenico F, Barone E, Mancuso C, Perluigi M, Cocciolo A, Mecocci P, Butterfield DA, Coccia R. HO-­‐
1/BVR-­‐A System Analysis in Plasma from Probable Alzheimer's Disease and Mild Cognitive Impairment Subjects: A Potential Biochemical Marker for the Prediction of the Disease JOURNAL OF ALZHEIMER DISEASE 2012 717. Galeotti F, Vanacore N, Gainotti S, Izzicupo F, Menniti-­‐Ippolito F, Petrini C, Chiarotti F, Chattat R, Raschetti R; AdCare Study Group. How legislation on decisional capacity can negatively affect the feasibility of clinical trials in patients with dementia .DRUGS & AGING.2012 48 718. Mangialasche F., Xu W., Kivipelto M., Costanzi E., Ercolani S., Pigliautile M., Cecchetti R., Baglioni M., Croce M.F., Simmons A., Soininen H., Tsolaki M., Kloszewska I., Vellas B., Lovestone S. and Mecocci P., on behalf of the AddNeuroMed Consortium. Tocopherols and tocotrienols plasma levels are associated with cognitive impairment. NEUROBIOLOGY OF AGING. 2012 719. Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S; AddNeuroMed Consortium, Dobson R Alzheimer's Disease Neuroimaging Initiative .Identification of cis-­‐ regulatory variation influencing protein abundance levels in human plasma. HUMAN MOLECULAR GENETICS.2012 720. Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, Simmons A, Lovestone S, Dobson R, Hodges A. Mitochondrial Dysfunction and Immune Activation are Detectable in Early Alzheimer's Disease Blood. JOURNAL OF ALZHEIMER DISEASE 2012 721. Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M, Pritchard M, Lord K, Martin BM, Craig D, Todd S, McGuinness B, Hollingworth P, Harold D, Kloszewska I, Soininen H, Mecocci P, Velas B, Gill M, Lawlor B, Rubinsztein DC, Brayne C, Passmore PA, Williams J, Lovestone S, Powell JF. Alzheimer's disease and age-­‐related macular degeneration have different genetic models for complement gene variation .NEUROBIOL AGING. 2012 722. Riaño D, Real F, López-­‐Vallverdú JA, Campana F, Ercolani S, Mecocci P, Annicchiarico R, Caltagirone C. An ontology-­‐based personalization of health-­‐care knowledge to support clinical decisions for chronically ill patients. JOURNAL OF BIOMEDICAL INFORMATICS. 2012 723. Mecocci P., Polidori M.C. Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease. BIOCHIMICA ET BIOPHYSICA ACTA. 2012 724. Whitehead D., Tunnard C., Hurt C., Wahlund L.O., Mecocci P., Tsolaki M., Vellas B., Spenger C., Kłoszewska I., Soininen H., Cromb D., Lovestone S., Simmons A. Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease INTERNATIONAL PSYCHOGERIATRICS.2012 725. Liu Y, Julkunen V, Paajanen T, Westman E, Wahlund LO, Aitken A, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H; AddNeuroMed Consortium. Education increases reserve against Alzheimer's disease-­‐evidence from structural MRI analysis NEURORADIOLOGY 2012 726. Pigliautile M., Ricci M., Mioshi E., Ercolani S., Mangialasche F., Monastero R., Croce M.F., Federici S., Mecocci P. Validation Study of the Italian Addenbrooke's Cognitive Examination Revised in a Young-­‐Old and Old-­‐Old Population DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2011 727. Westman E., Simmons A., Muehlboeck J.S., Mecocci P., Vellas B., Tsolaki M., Kłoszewska I., Soininen H., Weiner M.W., Lovestone S., Spenger C., Wahlund L.O. for the AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative . AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America NEUROIMAGE 2011 728. Tunnard C., Whitehead D., Hurt C., Wahlund L., Mecocci P., Tsolaki M., Vellas B., Spenger C., Kłoszewska I., Soininen H., Lovestone S., Simmons A. on behalf of the AddNeuroMed Consortium. Apathy and cortical atrophy in Alzheimer's disease . INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2011 729. Costafreda SG, Dinov ID, Tu Z, Shi Y, Liu CY, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund LO, Spenger C, Toga AW, Lovestone S, Simmons A . Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment. NEUROIMAGE. 2011 730. Liu Y., Paajanen T., Zhang Y., Westman E., Wahlund L.O., Simmons A., Tunnard C., Sobow T., Mecocci P., Tsolaki M., Vellas B., Muehlboeck S., Evans A., Spenger C., Lovestone S., Soininen H. for the AddNeuroMed Consortium. Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups-­‐The AddNeuroMed study NEUROBIOLOGY OF AGING. 2011 731. Furney S.J., Kronenberg D., Simmons A., Güntert A., Dobson R.J., Proitsi P., Wahlund L.O., Kloszewska I., Mecocci P., Soininen H., Tsolaki M., Vellas B., Spenger C., Lovestone S. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease-­‐-­‐cytokines and MRI measures together predict disease progression .JOURNAL OF ALZHEIMERS DISEASE. 2011 732. Lupton M.K., Proitsi P., Danillidou M., Tsolaki M., Hamilton G., Wroe R., Pritchard M., Lord K., Martin B.M., Kloszewska I., Soininen H., Mecocci P., Vellas B., Harold D., Hollingworth P., Lovestone S., Powell J.F . Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease. PLoS One. 2011 733. Savino M, Seripa D, Gallo AP, Garrubba M, D'Onofrio G, Bizzarro A, Paroni G, Paris F, Mecocci P, Masullo C, Pilotto A, Santini S.A Effectiveness of a high-­‐throughput genetic analysis in the identification of responders/non-­‐responders to CYP2D6-­‐metabolized drugs. CLINICAL LABORATORY.2011 49 734. Furney S.J., Simmons A., Breen G., Pedroso I., Lunnon K., Proitsi P., Hodges A., Powell J., Wahlund L.O., Kloszewska I., Mecocci P., Soininen H., Tsolaki M., Vellas B., Spenger C., Lathrop M., Shen L., Kim S., Saykin A.J., Weiner M.W., Lovestone S. Genome-­‐wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. MOLECULAR PSYCHIATRY. 2011 735. Sultana R., Mecocci P., Mangialasche F., Cecchetti R., Baglioni M., Butterfield D. AIncreased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker for this dementing disorder JOURNAL OF ALZHEIMERS DISEASE. 2011 736. Tiribuzi R., Orlacchio A., Crispoltoni L., Maiotti M., Zampolini M., De Angeliz M., Mecocci P., Cecchetti R., Bernardi G., Datti A., Martino S., Orlacchio A. Lysosomal β-­‐galactosidase and β-­‐hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimer's disease and type 2 diabetes mellitus JOURNAL OF ALZHEIMERS DISEASE. 2011 737. Westman E., Simmons A., Zhang Y., Muehlboeck J.S., Tunnard C., Liu Y., Collins L., Evans A., Mecocci P., Vellas B., Tsolaki M., Kłoszewska I., Soininen H., Lovestone S., Spenger C., Wahlund L.O. for the AddNeuroMed consortium. Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls. NEUROIMAGE. 2011 738. Panza F., Seripa D., D'Onofrio G., Frisardi V., Solfrizzi V., Mecocci P., Pilotto A. Neuropsychiatric Symptoms, Endophenotypes, and Syndromes in Late-­‐Onset Alzheimer's Disease: Focus on APOE Gene. International journal of Alzheimer's disease. . 2011 739. Bennett S., Grant M., Creese A.J., Mangialasche F., Cecchetti R., Cooper H.J., Mecocci P., Aldred S . Plasma Levels of Complement 4a Protein are Increased in Alzheimer's Disease.. ALZHEIMER DISEASE & ASSOCIATED DISORDERS. 2011 740. Seripa D., Bizzarro A., Pilotto A., D’onofrio G., Vecchione G., Gallo A.P., Cascavilla L., Paris F., Grandone E., Mecocci P., Santini S.A., Masullo C., Role of cytochrome P4502D6 functional polymorphisms in the efficacy of donepezil in patients with Alzheimer's disease . HARMACOGENETICS AND GENOMICS. 2011 741. Pilotto A, Westman E., Cavallin L., Muehlboeck J.S., Zhang Y., Mecocci P., Vellas B., Tsolaki M., Kłoszewska I., Soininen H., Spenger C., Lovestone S., Simmons A., Wahlund L.O. for the AddNeuroMed consortium Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease PLoS One 2011 742. Simmons A., Westman E., Muehlboeck S., Mecocci P., Vellas B., Tsolaki M., Kłoszewska I., Wahlund L.O., Soininen H., Lovestone S., Evans A., Spenger C. The AddNeuroMed framework for multi-­‐centre MRI assessment of Alzheimer's disease: experience from the first 24 months INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY 2011 743. Ricci M., Cornacchiola V., Pigliautile M., Ercolani S., Mecocci P. Fetal variant of circle of the Willis and bilateral symmetrical parietal stroke NEUROLOGICAL SCIENCES 2011 744. Thambisetty M, Simmons A, Hye A, Campbell J, Westman E, Zhang Y, Wahlund LO, Kinsey A, Causevic M, Killick R, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S; AddNeuroMed Consortium. Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease. PLoS One. 2011 745. Mangialasche F., Solomon A., Winblad B., Mecocci P., Kivipelto M. Alzheimer's disease: clinical trials and drug development LANCET NEUROLOGY. 2011 746. Liu Y., Paajanen T., Zhang Y., Westman E., Wahlund L.O., Simmons A., Tunnard C., Sobow T., Mecocci P., Tsolaki M., Vellas B., Muehlboeck S., Evans A., Spenger C., Lovestone S., Soininen H. for the AddNeuroMed Consortium. Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease . NEUROBIOLOGY OF AGING. 2011 747. Liu Y., Paajanen T., Westman E., Zhang Y., Wahlund L.O., Simmons A., Tunnard C., Sobow T., Proitsi P., Powell J., Mecocci P., Tsolaki M., Vellas B., Muehlboeck S., Evans A., Spenger C., Lovestone S., Soininen H. APOE e2 allele is associated with larger regional cortical thicknesses and volumes DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2011 748. Giacconi R., Kanoni S., Mecocci P., Malavolta M., Richter D., Pierpaoli S., Costarelli L., Cipriano C., Muti E., Mangialasche F., Piacenza F., Tesei S., Galeazzi R., Theodoraki E.V., Lattanzio F., Dedoussis G., Mocchegiani E. Association of MT1A haplotype with cardiovascular disease and antioxidant enzyme defense in elderly Greek population: comparison with an Italian cohort. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2011 749. Thambisetty M., Simmons A., Velayudhan L., Hye A., Campbell J., Zhang Y., Wahlund L.O., Westman E., Kinsey A., Güntert A., Proitsi P., Powell J., Causevic M., Killick R., Lunnon K., Lynham S., Broadstock M., Choudhry F., Howlett D.R., Williams R.J., Sharp S.I., Mitchelmore C., Tunnard C., Leung R., Foy C., O'Brien D., Breen G., Furney S.J., Ward M., Kloszewska I., Mecocci P., Soininen H., Tsolaki M., Vellas B., Hodges A., Murphy D.G., Parkins S., Richardson J.C., Resnick S.M., Ferrucci L., Wong D.F., Zhou Y., Muehlboeck S., 50 Evans A., Francis P.T., Spenger C., Lovestone S. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. ARCHIVES OF GENERAL PSYCHIATRY. 2011 750. Forti P., Rietti E., Pisacane N., Olivelli V., Dalmonte E., Mecocci P., Ravaglia G Blood homocysteine and risk of depression in the elderly. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2011 751. Paajanen T., Hänninen T., Tunnard C., Mecocci P., Sobow T., Tsolaki M., Vellas B., Lovestone S., Soininen H., Addneuromed Consortiu. CERAD Neuropsychological Battery Total Score in Multinational Mild Cognitive Impairment and Control Populations: The AddNeuroMed Study JOURNAL OF ALZHEIMERS DISEASE 2011 752. Feliziani F.T., Polidori M.C., De Rango P., Mangialasche F., Monastero R., Ercolani S., Raichi T., Cornacchiola V., Nelles G., Cao P., Mecocci P. Cognitive performance in elderly patients undergoing carotid endarterectomy or carotid artery stenting: a twelve-­‐month follow-­‐up study .CEREBROVASCULAR DISEASES. 2011 753. Aldred S., Mecocci P Decreased dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) concentrations in plasma of Alzheimer's disease (AD) patients. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2011 754. Liu Y., Paajanen T., Westman E., Wahlund L.O., Simmons A., Tunnard C., Sobow T., Proitsi P., Powell J., Mecocci P., Tsolaki M., Vellas B., Muehlboeck S, Evans A., Spenger C., Lovestone S., Soininen H. AddNeuroMed Consortium Effect of APOE e4 allele on cortical thicknesses and volumes: the AddNeuroMed study. JOURNAL OF ALZHEIMERS DISEASE. 2011 755. Maggio D., Ercolani S., Andreani S., Ruggiero C., Mariani E., Mangialasche F., Palmari N., Mecocci P. Emotional and psychological distress of persons involved in the care of patients with Alzheimer disease predicts falls and fractures in their care recipients DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2011 756. Mangialasche F., Kivipelto M., Mecocci P., Rizzuto D., Palmer K., Winblad B., Fratiglioni L .High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age. JOURNAL OF ALZHEIMERS DISEASE. 2011 757. Cherubini A., Lowenthal D.T., Paran E., Mecocci P., Williams L.S., Senin U. Hypertension and cognitive function in the elderly . DM DISEASE-­‐A-­‐MONTH. 2011 758. Aldred S., Bennett S., Mecocci P.. Increased low-­‐density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease. CLINICAL BIOCHEMISTRY.2011 759. Hurt C.S., Banerjee S., Tunnard C., Whitehead D., Tsolaki M., Mecocci P., Kloszewska I., Soininen H., Vellas B., Lovestone S. AddNeuroMed Consortium Insight, Cognition and Quality of Life in Alzheimer'S Disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2011 760. Forti P., Pisacane N., Rietti E., Lucicesare A., Olivelli V., Mariani E., Mecocci P., Ravaglia G. Metabolic syndrome and risk of dementia in older adults JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2011 761. Scafato E., Gandin C., Galluzzo L., Ghirini S., Cacciatore F., Capurso A., Solfrizzi V., Panza F., Cocchi A., Consoli D., Enzi G., Frisoni G.B., Gandolfo C., Giampaoli S., Inzitari D., Maggi S., Crepaldi G., Mariotti S., Mecocci P., Motta M., Negrini R., Postacchini D., Rengo F., Farchi G. I.PR.E.A. Working Group . Prevalence of aging-­‐associated cognitive decline in an Italian elderly population: results from cross-­‐sectional phase of Italian PRoject on Epidemiology of Alzheimer's disease (IPREA). AGING CLINICAL AND EXPERIMENTAL RESEARCH2011 762. Somberg J., Cherubini A., Lowenthal D.T., Paran E., Mecocci P., Williams L.S., Senin U., Hahr A.J., Molitch M.E., Cheng J.W., Frishman W.H., Aronow W.S. Topics in clinical pharmacology: cardiovascular and diabetes mellitus DM DISEASE-­‐A-­‐MONTH. 2011 763. 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410, ISSN: 2039-­‐9448-­‐ 2010 802. R. CIROCCHI, D'AJELLO F, TRASTULLI S, SANTORO A, DI ROCCO G, VENDETTUOLI D, RONDELLI F, GIANNOTTI D, SANGUINETTI A, Minelli L, REDLER A, BASOLI A, AVENIA N. Meta-­‐analisys of thyroidectomy with ultrasonic dissector versus conventional clamp and tie. WORLD JOURNAL OF SURGICAL ONCOLOGY, ISSN: 1477-­‐7819, doi: 10.1186/1477-­‐7819-­‐8-­‐112. 2010 53 803. Minelli L., Chiavarini M. La performance dei servizi sanitari materno-­‐infantili della Regione Umbria in termini di diseguaglianze di salute ed uso dei servizi: un confronto tra popolazione italiana e straniera In: M. Giannoni (a cura di). Equità nell'accesso ai servizi sanitari, disuguaglianze di salute e immigrazione. p. 308-­‐323, Milano:FrancoAngeli, ISBN: 9788856836455. 2010 804. CHIAVARINI M, BERNARDINI I, CASUCCI P, L. MINELLI. Donne straniere provenienti da Paesi a Forte Pressione Migratoria e percorso nascita in Umbria. In: -­‐. Epidemiologia e Prevenzione. Firenze, 6-­‐9 Novembre, vol. 5-­‐6 Suppl 1, Edizioni Inferenze. 2010 805. Chiavarini M., Bernardini I., Casucci P., Minelli L. Donne straniere provenienti da Paesi a Forte Pressione Migratoria e percorso nascita in Umbria.. In: -­‐. Epidemiologia e Prevenzione. EPIDEMIOLOGIA E PREVENZIONE, vol. Vol. 5-­‐6 (Suppl.1), p. 190. 2010 806. Minelli L., Casucci P., Bernardini I. Homogeneous Waiting Groups (RAO-­‐ Raggruppamenti di Attesa Omogenei): a model for an Italian Region, Umbria . In: -­‐. Health Service Research in Europe. The Hague, the Netherlands, 8-­‐9 april 2010, THE HAGUE M CHIAVARINI, A GILI, L PIERONI, L. MINELLI. Evaluation of appropriateness and determinants of caesarean section in an Italian region from 2007 to 2008. In: -­‐. European Journal of Public Health. Amsterdam, 10-­‐13 November, vol. 20, Suppl 1, p. 241.2010 807. Di Paolo A.M., Mazzoni F., Di Natale R., Bernardini I., Minelli L. (2010). Contraccezione e Percorso nascita. Confronto tra le grandi religioni.. Perugia:AUS edizioni.2010 808. L.Minelli, M.Chiavarini (2010). Le nascite in Umbria -­‐ Rapporto sui dati del Certificato di Assistenza al Parto, anno 2008. vol. 4, Perugia:Agenzia Umbria Sanità 809. Campus G., Solinas G., Strohmenger L., Cagetti M.G., Senna A., Minelli L., Majori S., Montgna M., Reali D., Castiglia P. (2009). National Pathfinder Survay on Children's Oral Health in Italy: Pattern and Severity of Caries Disease in 4-­‐Year-­‐Olds . CARIES RESEARCH, vol. 43, p. 155-­‐162, ISSN: 0008-­‐6568. 2009 810. Minelli L., Casucci P., Pakpahan E., Chiavarini M. Social class inequalities in perinatal health in Umbria (Italy), 2007. EUROPEAN JOURNAL OF PUBLIC HEALTH, vol. 19, Suppl 1, ISSN: 1101-­‐1262. 2009 811. Di Paolo A.M., Fumu L.M., Minelli L., Di Renzo G. (2008). Il Certificato di assistenza al parto come strumento informativo per una analisi del percorso nascita. MINERVA GINECOLOGICA, vol. 60, p. 339-­‐344, ISSN: 0026-­‐4784 812. Chiavarini M., Minelli L. Informazioni e comportamenti sessuali in un gruppo di adolescenti umbri. EDUCAZIONE SANITARIA E PROMOZIONE DELLA SALUTE, vol. 31, p. 56-­‐63, ISSN: 1124-­‐3651. 2008 813. Romagnoli C., Minelli L. Meta-­‐organizzazione e innovazione nel governo della salute. L'esperienza del Servizio sanitario umbro. POLITICHE SANITARIE, vol. 9, p. 133-­‐138, ISSN: 1590-­‐069X 2008 814. Cassetti T., Stracci F., Minelli L., Scheibel M., Sapia I.E., La Rosa F. Metachronous malignancies in men with previous prostate cancer in Umbria, Italy, 1994-­‐2003 . TUMORI, vol. 94, p. 7-­‐10, ISSN: 0300-­‐8916. 2008 815. Chiavarini M., Minelli L. Outcome della nascita pretermine: una breve review . MEDICO E BAMBINO, vol. 27 (4), p. 235-­‐238, ISSN: 1591-­‐3090 .2008 816. Romagnoli C., Minelli L. Ricerca scientifica in campo sanitario e Programmazione regionale: l'esperienza dell'Umbria. IGIENE E SANITÀ PUBBLICA, vol. LXIV, p. 685-­‐702, ISSN: 0019-­‐1639. 2008 817. Bussini O., Lanari D., Calzola L., Minelli L. (2008). Caratteristiche demografiche, antropometriche e socio-­‐
sanitarie delle leve militari in Umbria da fine Ottocento a fine Novecento. In: C.A. CORSINI (a cura di): Statura, salute e migrazioni: le leve militari italiane. p. 47-­‐75, Udine:Forum editrice, ISBN: 9788884204448.2008 Nocentini Giuseppe 818. Ayroldi E, Cannarile L, Migliorati G, Nocentini G, Delfino DV, Riccardi C. Mechanisms of the anti-­‐
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GITR system alters TLR-­‐4 expression on DC during fungal infection. Cell Immunol. 2009, 257(1-­‐2):13-­‐22 831. Cantarella G, Di Benedetto G, Scollo M, Paterniti I, Cuzzocrea S, Bosco P, Nocentini G, Riccardi C, Bernardini R. Neutralization of Tumor Necrosis Factor-­‐Related Apoptosis-­‐Inducing Ligand reduces spinal cord injury damage in mice.Neuropsychopharmacology. 2010; 35(6):1302-­‐14. 832. Alunno A, Bartoloni E, Nocentini G, Bistoni O, Ronchetti S, Petrillo MG, Riccardi C, Gerli R.Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis.Autoimmun Highlights, 1:45-­‐51. 2010 833. Alunno A, Nocentini G, Bistoni O, Bianchini R, Bartoloni Bocci E, Riccardi C, Gerli R.Glucocorticoid-­‐induced TNFR-­‐related protein (GITR) come marker di cellule T regolatorie umane:espansione della sottopopolazione cellulare GITR+CD25-­‐ in pazienti affetti da lupus eritematoso sistemico. Reumatismo 2010; 62(3):195-­‐201. 834. Nocentini G, Riccardi C. GITR: a modulator of immune response and inflammation. In: Therapeutic targets of the Tumor Necrosis Factor Superfamily (editore Iqbal Grewal). 2009, Chapter 11, pages 156-­‐173. Adv Exp Med Biol. 2009;647:156-­‐73. 835. Gerli R, Nocentini G, Alunno A, Bartoloni Bocci E, Bianchini R, Bistoni O, Riccardi C. Identification of regulatory T cells in systemic lupus erithematosus. Autoimmun Rev 2009, Mar;8(5):426-­‐30 836. Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C.Peroxisome Proliferator-­‐Activated Receptor-­‐α Contributes to the Anti-­‐Inflammatory Activity of Glucocorticoids Mol Pharmacol 2008, 73:323-­‐337. 837. Nocentini G, Cuzzocrea S, Genovese T, Bianchini R, Mazzon E, Ronchetti S, Esposito E, Di Paola R, Bramanti P and Riccardi C. GITR-­‐Fc fusion protein inhibits GITR triggering and protects from the inflammatory response following spinal cord injury. Mol Pharmacol 2008, Jun;73(6):1610-­‐1621. 838.
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Stroke,2012 931. Schillaci G, Battista F, Pucci G. A review of the role of electrocardiography in the diagnosis of left ventricular hypertrophy in hypertension. J Electrocardiol, 2012 60 932. Bacharova L, Estes EH, Hill JA, Pahlm O, Schillaci G, Strauss D,Wagner G. Changing role of ECG in the evaluation left ventricular hypertrophy. J Electrocardiol, 2012 933. Pirro M, Manfredelli MR, Helou RS, Scarponi AM, Schillaci G, Bagaglia F, Melis F, Mannarino E. Association of parathyroid hormone and 25-­‐OH-­‐vitamin D levels with arterial stiffness in postmenopausal women with vitamin D insufficiency. J Atheroscler Thromb, 2012 934. Pucci G, Battista F , Schillaci G. Aerobic physical exercise and arterial de-­‐stiffening: a recipe for vascular rejuvenation? Hypertens Res, 2012 935. Pirro M, Schillaci G, Mannarino MR, Scarponi AM, Manfredelli MR, Callarelli L, Leli C, Fabbriciani G, Helou RS, Bagaglia F, Mannarino E. 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Schillaci G, De Vuono S, Pucci G. An endogenous brake on the sympathetic nervous system: the emerging role of catestatin in hypertension. J Cardiovasc Med, 2011 942. Pirro M, Del Giorno R, Lupattelli G, Mannarino MR, Roscini AR, Covelli D, Schillaci G, Pasqualini L, Bagaglia F, Siepi D, Mannarino E. Cardiovascular risk factors and recommended lipid goals attainment among patients referred in a tertiary care lipid clinic. Eur J Intern Med, 2011 943. Bacharova L, Estes EH, Bang LE, Hill JA, Macfarlane PW, Rowlandson I, Schillaci G. Second statement of the Working Group on Electrocardiographic Diagnosis of Left Ventricular Hypertrophy. J Electrocardiol, 2011 944. Schillaci G, Pucci G. The relationship between systolic and diastolic blood pressure: a clinically meaningful slope? Hypertens Res, 2011 945. Pasqualini L, Schillaci G, Innocente S, Pucci G, Coscia F, Siepi D, Lupattelli G, Ciuffetti G, Mannarino E. Lifestyle intervention improves microvascular reactivity and increases serum adiponectin in overweight hypertensive patients. Nutr Metab Cardiovasc Dis, 2010 946. Gerli R, Vaudo G, Bartoloni Bocci E, Schillaci G, Alunno A, Luccioli F, Hijazi DR, Mannarino E, Shoenfeld Y. Functional impairment of arterial wall in primary Sjögren's syndrome: combined action of immunological and inflammatory factors. Arthritis Care Res, 2010 947. Schillaci G, Grassi G. Central blood pressure: getting to the heart of the matter. J Hypertens, 2010 948. Bacharova L, Estes H, Bang L, Rowlandson I, Schillaci G, Verdecchia P, Macfarlane PW The first statement of the Working Group on Electrocardiographic Diagnosis of Left Ventricular Hypertrophy. J Electrocardiol, 2010 949. Schillaci G, Parati G. Determinants of blood pressure variability in youth: at the roots of hypertension. J Hypertens, 2010 950. Schillaci G, Pucci G. The dynamic relation between systolic and diastolic blood pressure: yet another marker of vascular aging? Hypertens Res, 2010 951. De Socio GVL, Bonfanti P, Martinelli C, Ricci E, Pucci G, Marinoni M, Vitiello P, Menzaghi B, Rizzardini G, Schillaci G. Negative influence of HIV infection on day-­‐night blood pressure variability. JAIDS-­‐J Acq Imm Def, 2010 952. Schillaci G, Sarchielli P, Corbelli I, Pucci G, Settimi L, Mannarino MR, Calabresi P, Mannarino E. Aortic stiffness and pulse wave reflection in young subjects with migraine: a case-­‐control study. Neurology, 2010 953. Schillaci G, Pucci G. Resistant hypertension. Intern Emerg Med, 2010 954. Natali A, Pucci G, Boldrini B, Schillaci G. Metabolic syndrome – at the crossroads of cardiorenal risk. J Nephrol, 2009 955. Schillaci G, Pirro M, Mannarino E. Assessing cardiovascular risk: should we discard diastolic blood pressure? Circulation, 2009 956. 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2):273-­‐82 (2010) 998. Alessandro Magini, Lorena Urbanelli, Virginia Ciccarone, Brunella Tancini, Mario Polidoro, Anna Maria Timperio, Lello Zolla, Andrea Tedde, Sandro Sorbi, Carla Emiliani. Fibroblasts from PS1 mutated pre-­‐
symptomatic subjects and Alzheimer’s disease patients share a unique protein levels profile. Journal of Alzheimer's Dis. Jan 1;21(2):431-­‐44 (2010) 999. Urbanelli L, Magini A, Ciccarone V, Trivelli F, Polidoro M, Tancini B, Emiliani C. New perspectives for the diagnosis of Alzheimer's disease. Recent Pat CNS Drug Discov. Nov;4(3):160-­‐81. (2009) 1000. Magini, S. Mencarelli, B. Tancini, V. Ciccarone, L. Urbanelli, A. Hasilik and C. Emiliani. Identification and characterization of mature beta-­‐hexosaminidases associated with human placenta lysosomal membrane. Biosci. Rep., 28 (4):229-­‐37 (2008) Vaccaro Luigi 1001. Bonollo S., Lanari D., Longo J. M., Vaccaro L. E-­‐factor minimized protocols for the polystyryl-­‐BEMP catalyzed conjugate additions of various nucleophiles to a,b-­‐unsaturated carbonyl compounds Green Chemistry vol. 14, p. 164-­‐169, 2012 1002. Bonollo S., Lanari D., Angelini T., Pizzo F., Marrocchi A., Vaccaro L. Rasta resin as support for TBD in base-­‐
catalyzed organic processes .JOURNAL OF CATALYSIS, vol. 285, p. 216-­‐222. 2012 1003. Lanari D., Bonollo S., Vaccaro L.[ 2]Catenanes on Surfaces as Candidates for Nanoelectronic Devices CURRENT ORGANIC SYNTHESIS, vol. 9/2012, p. 188-­‐198,. 2012 1004. Marrocchi A., Lanari D., Facchetti A., Vaccaro L. Poly(3-­‐hexylthiophene): synthetic methodologies and properties in bulk heterojunction solar cells. ENERGY & ENVIRONMENTAL SCIENCE, vol. 5, p. 8457-­‐8474. 2012 1005. Marrocchi A., Tomasi I., Vaccaro L. Organic Small-­‐Molecules for Photonics and Electronics from the [2.2]Paracyclophane Scaffold .ISRAEL JOURNAL OF CHEMISTRY, vol. 52, p. 42-­‐52,2012 1006. P. Wolfer, M. L. Santarelli, L. Vaccaro, A. Broggi, D. Lanari, L. Yu, T. D. Anthopoulos, P. Smith, N. Stingelin-­‐
Stutzmann, A. Marrocchi .Semiconducting Arylacetylene:Insulating Polymer Blends for Organic-­‐Based Electronic Devices .MATERIALS RESEARCH SOCIETY SYMPOSIA PROCEEDINGS,ISSN: 0272-­‐9172 2012 1007. Facchetti A., Vaccaro L., Marrocchi A. Semiconducting Polymers via Direct Arylation Polycondensation ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 51, p. 3520-­‐3523, 2012 1008. Angelini T., Lanari D., Maggi R., Pizzo F., Sartori G., Vaccaro L. Preparation and use of polystyryl-­‐DabcoF2: An efficient recoverable and reusable catalyst for beta -­‐azidation of alfa-­‐beta unsaturated ketones in water .ADVANCED SYNTHESIS & CATALYSIS, vol. 2012, p. 908-­‐916. 2012 1009. Lanari D., Piermatti O., Pizzo F., Vaccaro l. Copper(II) triflate-­‐sodium dodecyl sulfate catalyzed preparation of 1,2-­‐diphenyl-­‐2,3-­‐dihydro-­‐4-­‐pyridones in aqueous acidic medium .SYNTHESIS-­‐Stuttgart, p. 2181-­‐2184,2012 1010. Strappaveccia G., Lanari D., Gelman D., Pizzo F., Rosati O., Curini M., Vaccaro L. Efficient synthesis of cyanohydrin trimethylsilyl ethers via 1,2-­‐chemoselective cyanosilylation of carbonyls. GREEN CHEMISTRY, vol. 14, p. 10.1039/C2GC364. 2012 1011. Angelini T., Bonollo S., Lanari D., Pizzo F., Vaccaro L. A Protocol for Accessing the beta-­‐Azidation of alpha,beta-­‐Unsaturated Carboxylic Acids .ORGANIC LETTERS, vol. 14, p. 4610-­‐4613.2012 1012. Lanari D., Piermatti O., Pizzo F., Vaccaro L., Water as Reaction Medium in the Synthetic Processes Involving Epoxides. In: -­‐. Green Solvents I, Porperties and Applications. p. 209-­‐232,. 2012 1013. Vaccaro L. NEW SYNTHETIC TOOLS FOR THE DEFINITION OF SUSTAINABLE CONTINUOUS-­‐FLOW REACTORS. LA CHIMICA E L'INDUSTRIA, p. 64-­‐68, I. 2012 1014. Gabrielli S., Palmieri A., Panmand D. S., Lanari D., Vaccaro L., Ballini R. Nitroacrylates as key starting materials for the one-­‐pot Nitroacrylates as key starting materials for the one-­‐pot synthesis of densely 64 functionalized penta-­‐substituted anilines synthesis of densely functionalized penta-­‐substituted anilines .TETRAHEDRON, vol. 68, p. 8231-­‐.2012 1015. Angelini T., Lanari D., Maggi R., Sartori G., Pizzo F., Vaccaro L. beta-­‐Azidation of alpha,beta-­‐unsaturated ketones using PS-­‐DABCOF2 .SYNFACTS, vol. 8, p. 0689,2012 1016. Vaccaro L. Nominated as Member of the " Ad Hoc Working Group on Tools and Approaches to Support Decision-­‐Making on the Substitution of Harmful Chemicals” a joining action of the Organisation for Economic Co-­‐operation and Development (OECD) and the US Environmental Protection Agency (US EPA) that holds the presidency. 2012 1017. Vaccaro L. Elected in the board of the Green Chemistry Interdivision of the Società Chimica Italiana (SCI).2012 1018. Vaccaro L. Elected in the Scientific Board of the journal "GREEN" a publication of the Consorzio Interuniversitario Nazionale "La Chimica per l'Ambiente" (INCA) 2012 1019. Imbergamo E., Vaccaro L titolo "GUIDA DI LUCE", Numero di domanda di brevetto RM2012A000387.2012 1020. Imbergamo E., Vaccaro L titolo "SISTEMA D'ILLUMINAZIONE A LUCE SOLARE PER MEZZI DI TRASPORTO" Numero di domanda di brevetto RM2012A000387 2012 1021. S. Bonollo, D. Lanari, F. Pizzo, Vaccaro L. Sc(III)-­‐catalyzed enantioselective addition of thiols to α,β-­‐
unsaturated ketones in neutral water. Org.Lett. 13, 2150–2152. 2011 1022. S. Bonollo, D. Lanari, Vaccaro L. Ring-­‐opening of epoxides in water Eur. J. Org. 2587–2598. 2011 1023. S. Bonollo, D. Lanari, A. Marrocchi Vaccaro L. Stereoselective ring-­‐opening reactions of epoxides in water .Curr. Org. Synth. 8, 319-­‐329. 2011 1024. Palmieri, S. Gabrielli, D. Lanari, Vaccaro L. New one-­‐pot synthesis of polysubstituted indoles from pyrroles and β-­‐nitroacrylates Adv. Synth. Catal. 353, 1425–1428. 2011 1025. P. Wolfer, M. L. Santarelli, Vaccaro L., L. Yu, T. D. Anthopoulos, P. Smith, N. Stingelin, A. Marrocch . Influence of molecular architecture and processing on properties of semiconducting arylacetylene: Insulating poly(vinylidene fluoride) blends. Org. Electron. 12, 1886–1892. 2011 1026. D. Lanari, R. Ballini, A. Palmieri, F. Pizzo, Vaccaro L Diastereoselective three-­‐step route to o-­‐(6-­‐
nitrocyclohex-­‐3-­‐en-­‐1-­‐yl)phenol and tetrahydro-­‐6h-­‐benzo[c]chromen-­‐6-­‐ol derivatives from salicylaldehydes. Eur. J. Org. Chem. 2874–2884. 2011 1027. D. Lanari, R. Ballini, S. Bonollo, A. Palmieri, F. Pizzo, Vaccaro L JandaJel as a polymeric support to improve the catalytic efficiency of immobilized-­‐1,5,7-­‐triazabicyclo[4.4.0]dec-­‐5-­‐ene (TBD) under solvent-­‐
free conditions. Green Chem. 13, 3181-­‐3186. 2011 1028. S. Calogero, D. Lanari, M. Orrù, O. Piermatti, F. Pizzo, Vaccaro L. Supported L-­‐proline on zirconium phosphates methyl and/or phenyl phosphonates as heterogeneous organocatalysts for direct asymmetric aldol addition. J. Catal. 277 112–119. 2011 1029. R. Maggi, D. Lanari, C. Oro, G. Sartori, Vaccaro L. Heterogeneous bisoxazoline/copper complex: a green catalyst for the enantioselective reaction of nitromethane with substituted benzaldehydes. Eur. J. Org. Chem. 5551–5554. 2011 1030. S. Bonollo, D. Lanari, F. Pizzo, L. Vaccaro. Scandium-­‐catalyzed asymmetric sulfa-­‐Muchael addition. SYNFACTS, vol. 8, p. 0881,. 2011 1031. L. Vaccaro. PROCESSI IN FLUSSO CONTINUO PER LO SVILUPPO DI UNA CHIMICA ORGANICASOSTENIBILE. LA CHIMICA E L'INDUSTRIA, p. 122-­‐127,. 2011 1032. ZVAGULIS, A. BONOLLO, S. LANARI D., PIZZO F., VACCARO L. 2-­‐tert-­‐Butylimino-­‐2-­‐diethylamino-­‐1,3-­‐
dimethylperhydro-­‐1,3,2-­‐diazaphosphorine supported on polystyrene (PS-­‐BEMP)as an efficient recoverable an reusable catalyst for the phenolysis of epoxides under solvent-­‐free conditions.ADV. SYNTH. CATAL., vol. 352; p. 2489-­‐2496, 2010 1033. T. ANGELINI , F. FRINGUELLI , D. LANARI , PIZZO F:, VACCARO L. A catalytic approach to the base-­‐
promoted reaction of epoxides with activated methylenes. TETRAHEDRON LETTERS, vol. 51; p. 1566-­‐1569, 2010 1034. F. FRINGUELLI, O. PIERMATTI, PIZZO F. , VACCARO L Diels-­‐Alder Reactions. STUTTGART: Georg Thieme Verlag KG .Science of Synthesis. vol. 47, p. 561-­‐736 2010 1035. Vaccaro L Nominated by the Italian Chemical Society as representative for the EUCHEM Organic Division Young Investigator's Workshop in Regensburg, D, 27-­‐29th/08/2010. 2010 1036. FRINGUELLI F, LANARI D, PIZZO F, VACCARO L Solid-­‐Supported Ammonium Fluorides in Organic Synthesis. CURRENT ORGANIC SYNTHESIS, vol. 6; p. 203-­‐218,2010 1037. LANARI D, VACCARO Critical Surveys Covering the Year 2008. 2009 1038. VACCARO L., BALLINI R, BARBONI L, CASTRICA L, FRINGUELLI F, LANARI D, PIZZO F Polystyryl-­‐BEMP as an Efficient Recyclable Catalyst for the Nucleophilic Addition of Nitroalkanes to a,b-­‐Unsaturated Carbonyl 65 Compounds under Solvent-­‐Free Conditions. ADVANCED SYNTHESIS & CATALYSIS, vol. 350; p. 1218-­‐1224, 2008 1039. VACCARO L., BALLINI R, BOSICA G, PALMIERI A, PIZZO, F. Isolute Si-­‐carbonate catalyzes the nitronate addition to both aldehydes and electron-­‐poor alkenes under solvent-­‐free conditions. GREEN CHEMISTRY, vol. 10; p. 541-­‐544, 2008 1040. VACCARO L., BONOLLO S, FRINGUELLI F, PIZZO F. Zn(II)-­‐Catalyzed Desymmetrization of meso-­‐Epoxides by Aromatic Amines in Water. SYNLETT; p. 1574-­‐1578, 2008 1041. VACCARO L., CASTRICA L, FRINGUELLI F, PIZZO F.Catalyst-­‐ and solvent-­‐free conditions as an environmentally benign approach to 4-­‐aryl-­‐3-­‐cyano-­‐hexahydro-­‐4H-­‐1,2-­‐benzoxazine-­‐2-­‐oxides. GREEN CHEMISTRY, vol. 10; p. 327-­‐332, 2008 1042. VACCARO L., CASTRICA L, FRINGUELLI F, PIZZO F .Enantioselective Michael Addition of Dimethyl Malonate to (E)-­‐beta-­‐Nitrostyrenes Catalyzed by Cinchona Alkaloids under Solvent-­‐Free Condition. LETTERS IN ORGANIC CHEMISTRY, vol. 5; p. 602-­‐606, 2008 1043. VACCARO L., FRINGUELLI F, LANARI D, PIZZO F. Amberlite IRA900F as a Solid Fluoride Source for a Variety of Organic Transformations under Solvent-­‐Free Conditions. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; p. 3928-­‐3932. 2008 66 Indicatori individuali per l’Abilitazione Scientifica Nazionale dei 16 Membri di riferimento del collegio (Riferimenti: Delibera ANVUR “Modalità di calcolo degli indicatori” del 21 giugno 2012). DOCENTI DI SETTORI BIBLIOMETRICI Elencare gli indicatori individuali dei 16 membri di riferimento secondo il seguente schema: Docente N Cognome 1 Riccardi Carlo Achilli Alessandro Avenia Nicola Cruciani Gabriele Elisei Fausto Fagotti Anna Fioretto Daniele Gammaitoni Luca Gerli Roberto Gigliotti Giovanni Grignani Franco Latterini Loredana Marcotullio Carla Mecocci Patrizia Schillaci Giuseppe Vaccaro Luigi 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Nome INDICATORI se Professore II Fascia (per candidati all'abilitazione scientifica nazionale a professore ordinario) INDICATORI se Professore I Fascia (per candidatura commissari dell'abilitazione scientifica nazionale) INDICATORI se Ricercatore (per candidati all'abilitazione scientifica nazionale a professore associato) Numero ARTICOLI Numero CITAZIONI INDICE H Numero ARTICOLI NORM.TO Numero CITAZIONI NORM.TO INDICE H-­‐C Numero ARTICOLI NORM.TO Numero CITAZIONI NORM.TO INDICE H-­‐C 316 11057 44 63 203 22 139 65 16 112 4352 35 141 3239 28 89 90 20 132 2089 27 230 10555 43 228 4323 35 38 743 15 82 7309 32 59 70 15 40 48 11 198 5479 39 223 580 32 59 138 18 67 Indicatori individuali per l’Abilitazione Scientifica Nazionale dei 16 Membri di riferimento del collegio (Riferimenti: Delibera ANVUR “Modalità di calcolo degli indicatori” del 21 giugno 2012). DOCENTI DI SETTORI NON BIBLIOMETRICI Elencare gli indicatori individuali dei 16 membri di riferimento secondo il seguente schema: INDICATORI se Professore I Fascia (per candidatura commissari dell'abilitazione scientifica nazionale) Docente N Cognome Nome 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 INDICATORI se Professore II INDICATORI se Ricercatore Fascia (per candidati (per candidati all'abilitazione all'abilitazione scientifica scientifica nazionale a professore nazionale a professore ordinario) associato) Numero ARTICOLI SU RIVISTE DI CLASSE A Numero LIBRI DOTATI DI ISBN NORM.TO Numero ARTICOLI SU RIVISTA E CAPITOLI DI LIBRI DOTATI DI ISBN NORM.TO Numero ARTICOLI SU RIVISTE DI CLASSE A NORM.TO Numero LIBRI DOTATI DI ISBN NORM.TO Numero ARTICOLI SU RIVISTA E CAPITOLI DI LIBRI DOTATI DI ISBN NORM.TO Numero ARTICOLI SU RIVISTE DI CLASSE A NORM.TO Numero LIBRI DOTATI DI ISBN Numero ARTICOLI SU RIVISTA E CAPITOLI DI LIBRI DOTATI DI ISBN 68 Pubblicazioni 16 Membri di riferimento Produzione scientifica dei membri del Collegio degli ultimi 5 anni (dal 2008 al 2012) (16 membri di riferimento del Collegio) Indicare l'intera produzione scientifica dei 5 anni, specificando le n.5 pubblicazioni significative. Le pubblicazioni comuni a più autori appartenenti al collegio dovranno essere ripetute, con l’indicazione per ciascuna di esse del numero di autori membri di riferimento del collegio stesso. Elencare le pubblicazioni secondo il seguente schema: n. prog
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e significativa IF Glucocorticoid-­‐induced leucine zipper (GILZ) over–expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury Spri
nge Neurotherape
utics 2012 6,10 Pharmacological modulation of GITRL/GITR Wile
y system: therapeutic perspectives. Onli
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(L-­‐GILZ) interacts with Ras pathway and MB Br. J. Pharmacol. 2012 4,92 A E. Esposito, S. Bruscoli, E. Mazzon, I. 8 S Paterniti, M. Coppo, E. Velardi, S. Cuzzocrea and C. Riccardi A G. Nocentini, S. Ronchetti, M.G. S Petrillo and C. Riccardi 4 A S. Bruscoli, E. Velardi, M. Di Sante, 11 S O. Bereshchenko, A. Venanzi, M. Coppo, V. Berno, M. G. Mameli, R. Colella, A. Cavaliere and C. Riccardi J. Biol. Chem. 2012 5,33 PLoS One 2012 4,41 contributes to spermatogenesis control. 4 A L. Sinik Teodorovic, C. Riccardi, R.M. S Torres and R. Pelanda 4 5 A S. Ronchetti, G. Nocentini, M.G. S Petrillo, C. Riccardi 4 Murine B Cell Development and Antibody Responses to Model Antigens Are Not Impaired in the Absence of the TNF Receptor GITR. CD8(+) T Cells: GITR Matters. PUB
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d Journal 2012 1,65 6 A A. Alunno, E. Bartoloni, O. Bistoni, G. S Nocentini, S. Ronchetti, S. Caterbi, V. Valentini, C. Riccardi and R. Gerli 9 7 A O. Bereshchenko, E. Mancini, L. S Luciani, A. Gambardella, C. Riccardi and C. Nerlov 6 8 A L. McKlvey, H. Gutierrez, G. 7 S Nocentini, SJ Crampton, AM Davies, C. Riccardi, CW O’keeffe A E. Ayroldi, L.Cannarile, G. Migliorati, S G. Nocentini, DV. Delfino, C. Riccardi Hind
awi Publi
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NGF-­‐promoted neurite growth through an pany inverse modulation of Erk and NF-­‐κB of signaling. Biolo
Clin Dev Immunol. 2012 1,73 Haemathologi
ca 2012 significativa 6,53 Biol Open 2012 5,70 gists Ltd 9 Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New. 6 Mechanisms of the anti-­‐inflammatory The effects of glucocorticoids: genomic and Feder
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neurological symptoms in ataxia-­‐ y Onli
telangiectasia. ne libra
ry Glucocorticoidi-­‐Induced TNFR family Related Else
gene (GITR) enhances dendritic cell activity. vier Eur. J. Neurol. 2011 3,76 Immunol. Lett. 2011 2,51 15 17 of Amer
ican Socie
ties for Exper
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tal Biolo
gy The glucocorticoid-­‐induced TNF receptor Wile
family-­‐related protein (GITR) is critical to the y development of acute pancreatitis in mice. Onli
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ry Glucocorticoid-­‐induced activation of Natu
caspase-­‐8 protects the glucocorticoid-­‐
re induced protein Gilz from proteasomal Pub.
degradation and induces its binding to grou
Sumo-­‐1 in murine thymocytes p Br. J. Pharmacol. 2011 4,92 Cell. Death Differ. 2011 significativa 9,05 Effect of dietary saturated fatty acid on HNF-­‐ Spri 4alfa DNA binding activity and ApoCIII mRNA nger in sedentary rat liver. Maesopsin 4-­‐O-­‐beta-­‐D-­‐glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-­‐regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia. Man
ey Publ
. Eicosapentaenoic acid demethylates a single ASB
CpG that mediates expression of tumor MB suppressor CCAAT/enhan cer-­‐binding protein delta in U937 leukemia cells. CD4(+) CD25(low) GITR(+) cells: a novel Wile
human CD4(+) T-­‐cell population with y regulatory activity. Onli
ne libra
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protein (GITR) contributes to the systemic y adjuvanticity of the Escherichia coli heat-­‐
Onli
labile enterotoxin. ne libra
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harmacology 2010 6,46 Shock 2009 3,20 Else
vier Autoimmun. Rev. 2009 significativa 6,55 The GITRL-­‐GITR system alters TLR-­‐4 Else
vier expression on DC during fungal infection. Cell. Immunol., 2009 2,70 24 A
S 25 A
S 26 A
S L. Riccardi E. Mazzon, S. Bruscoli, E. Esposito, C. Crisafulli, R. Di Paola, R. Caminiti, C. Riccardi, and S. Cuzzocrea R. Gerli, G. Nocentini, A. Alunno, E. Bartoloni Bocci, R. Bianchini, O. Bistoni, and C. Riccardi A. Vecchiarelli, E. Pericolini, E. Gabrielli, M. Agostini, F. Bistoni, G. Nocentini, E. Cenci, C. Riccardi 9 7 8 27 A E. Ayroldi, C. Riccardi S 2 28 A G. Nocentini, C. Riccardi S 2 29 A S. Cuzzocrea, S. Bruscoli, E. Mazzon, 10 S C. Crisafulli, V. Donato, R. Di Paola, E. Velardi, E. Esposito, G. Nocentini, and C. Riccardi A G.W. O’Keeffe H. Gutierrez, P. P. S Pandolfi, C.Riccardi, and A. M. Davie 30 Peroxisome proliferator-­‐activated receptor-­‐
alpha modulates the anti-­‐inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice. Identification of regulatory T cells in systemic lupus erythematosus. 5 Glucocorticoid-­‐induced leucine zipper (GILZ): a new important mediator of glucocorticoid action. GITR: A Modulator of Immune Response and Inflammation Peroxisome Proliferator-­‐Activated Receptor-­‐
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induced TNF receptor in CD1d-­‐dependent natural killer T cells. 33 A B. Cinque, D. Fanini, L. Di Marzio, P. S Palumbo, C. La Torre, V. Donato, E. Velardi, S. Bruscoli, C. Riccardi, and M.G. Cifone A L. Cannarile, S. Cuzzocrea, L. S Santucci, M. Agostini, E. Mazzon, E. 10 Involvement of cPLA2 inhibition in dexamethasone-­‐induced thymocyte apoptosis. 10 Glucocorticoid-­‐Induced Leucine Zipper Is Protective in Th1-­‐Mediated Models of 34 Glucocorticoid-­‐induced tumor necrosis factor receptor-­‐related (GITR)-­‐Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury. Amer
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8 1 Rare primary mitochondrial DNA mutations and probable synergistic variants in leber's hereditary optic neuropathy 41 42 37 38 39 Amer
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PLoS ONE 2012 significativa 3,73
0 Proceedings of the National Academy of Sciences of the United States of America 2012 9,73
7 CSK
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7 LIC LIBRA
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2 1 Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication Nati
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s Genome Research 2012 significativa 14,3
(Cover story 97 article) 15 1 Arrival of Paleo-­‐Indians to the Southern Cone of South America: New Clues from Mitogenomes PUBLI
C LIBRA
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0 A Gómez-­‐Carballa A, Olivieri A, Behar S DM, Achilli A, Torroni A, Salas A 6 1 Genetic continuity in the franco-­‐cantabrian region: New clues from autochthonous mitogenomes PLoS ONE 2012 3,73
0 A Grugni V, Battaglia V, Hooshiar S Kashani B, Parolo S, Al-­‐Zahery N, Achilli A, Olivieri A, Gandini F, Houshmand M, Sanati MH, Torroni A, Semino O 12 1 PLoS ONE 2012 3,73
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1 44 A Karachanak S, Carossa V, Nesheva D, S Olivieri A, Pala M, Hooshiar Kashani B, Grugni V, Battaglia V, Achilli A, 14 1 Bulgarians vs the other European populations: A mitochondrial DNA perspective International Journal of Legal 2012 2,68
6 40 PUBLI
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S 46 A
S 47 A Achilli A, Olivieri A, Pala M, Hooshiar S Kashani B, Carossa V, Perego UA, Gandini F, Santoro A, Battaglia V, Grugni V, Lancioni H, Sirolla C, Bonfigli AR, Cormio A, Boemi M, Testa I, Semino O, Ceriello A, Spazzafumo L, Gadaleta MN, Marra M, Testa R, Franceschi C, Torroni A A Albertini E, Raggi L, Vagnini M, S Sassolini A, Achilli A, Marconi G, Cartechini L, Veronesi F, Falcinelli M, Brunetti BG, Miliani C A Bonfiglio S, Achilli A, Olivieri A, S Negrini R, Colli L, Liotta L, Ajmone-­‐
Marsan P, Torroni A, Ferretti L 50 51 Medicine Mitochondrial DNA signals of late glacial recolonization of europe from near eastern refugia Cell Pres
s American Journal of Human Genetics 2012 11,2
02 Decrypting the mitochondrial gene pool of modern panamanians PUBLI
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NCE PLoS ONE 2012 3,73
0 26 1 Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole PLoS ONE 2011 11 1 Analytical and Bioanalytical Chemistry 2011 3,77
8 9 1 The enigmatic origin of bovine mtDNA haplogroup R: Sporadic interbreeding or an independent event of Bos primigenius domestication in Italy? PLoS ONE 2010 3,73
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gart 1958 Nominated as Member of the " Ad Hoc Working Group on Tools and Approaches to Support 2012 Decision-­‐Making on the Substitution of Harmful Chemicals” a joining action of the Organisation for Economic Co-­‐operation and Development (OECD) and the US Environmental Protection Agency (US EPA) that holds the presidency. Elected in the board of the Green Chemistry Interdivision of the Società Chimica Italiana (SCI). 2012 Elected in the Scientific Board of the journal "GREEN" a publication of the Consorzio Interuniversitario Nazionale "La Chimica per l'Ambiente" (INCA) http://www.incaweb.org/green/. 4 0 Sc(III)-­‐catalyzed enantioselective addition of ACS Org.Lett. 13, thiols to α,β-­‐unsaturated ketones in neutral 2150–2152 water A S. Bonollo, D. Lanari, Vaccaro L. 3 0 Ring-­‐opening of epoxides in water. Wile Eur. J. Org. S y 2587–2598 A S. Bonollo, D. Lanari, A. Marrocchi 4 0 Stereoselective ring-­‐opening reactions of Curr. Org. S Vaccaro L. epoxides in water. Bent
Synth. 8, ham 319-­‐329 Scie
nce A A. Palmieri, S. Gabrielli, D. Lanari, 4 1 New one-­‐pot synthesis of polysubstituted Wile Adv. Synth. S Vaccaro L. indoles from pyrroles and β-­‐nitroacrylates. y Catal. 353, 1425–1428 A P. Wolfer, M. L. Santarelli, Vaccaro L., 8 2 Influence of molecular architecture and Else Org. Electron. S L. Yu, T. D. Anthopoulos, P. Smith, N. processing on properties of semiconducting vier 12, 1886–1892 Stingelin, A. Marrocchi arylacetylene: Insulating poly(vinylidene fluoride) blends A D. Lanari, R. Ballini, A. Palmieri, F. 5 0 Diastereoselective three-­‐step route to o-­‐(6-­‐
Wile Eur. J. Org. S Pizzo, Vaccaro L. nitrocyclohex-­‐3-­‐en-­‐1-­‐yl)phenol and y Chem. 2874–
tetrahydro-­‐6h-­‐benzo[c]chromen-­‐6-­‐ol 2884 derivatives from salicylaldehydes A D. Lanari, R. Ballini, S. Bonollo, A. 6 0 JandaJel as a polymeric support to improve RSC Green Chem. S Palmieri, F. Pizzo, Vaccaro L. the catalytic efficiency of immobilized-­‐1,5,7-­‐
13, 3181-­‐3186 triazabicyclo[4.4.0]dec-­‐5-­‐ene (TBD) under solvent-­‐free conditions A S. Calogero, D. Lanari, M. Orrù, O. 6 1 Supported L-­‐proline on zirconium Else J. Catal. 277 S Piermatti, F. Pizzo, Vaccaro L. phosphates methyl and/or phenyl vier 112–119 phosphonates as heterogeneous organocatalysts for direct asymmetric aldol addition A R. Maggi, D. Lanari, C. Oro, G. Sartori, 5 1 Heterogeneous bisoxazoline/copper Wile Eur. J. Org. S Vaccaro L. complex: a green catalyst for the y Chem. 5551–
enantioselective reaction of nitromethane 5554 with substituted benzaldehydes A S. Bonollo, D. Lanari, F. Pizzo, L. 4 0 Scandium-­‐catalyzed asymmetric sulfa-­‐
Thie SYNFACTS, vol. S Vaccaro. Muchael addition me 8, p. 0881, C Stutt
ISSN: 1861-­‐
gart 1958 A L. Vaccaro 1 0 PROCESSI IN FLUSSO CONTINUO PER LO SCI LA CHIMICA E S
SVILUPPO DI UNA CHIMICA ORGANICA L'INDUSTRIA, C SOSTENIBILE. p. 122-­‐127, ISSN: 0009-­‐
4315 A ZVAGULIS, A. BONOLLO, S. LANARI 4 0 2-­‐tert-­‐Butylimino-­‐2-­‐diethylamino-­‐1,3-­‐
Wile ADV. SYNTH. S D., PIZZO F., VACCARO L. dimethylperhydro-­‐1,3,2-­‐diazaphosphorine y CATAL., vol. supported on polystyrene (PS-­‐BEMP)as an 352; p. 2489-­‐
efficient recoverable an reusable catalyst for 2496, ISSN: the phenolysis of epoxides under solvent-­‐
1615-­‐4150 free conditions A ZVAGULIS, A. BONOLLO, S. LANARI 4 0 2-­‐tert-­‐Butylimino-­‐2-­‐diethylamino-­‐1,3-­‐
Wile ADV. SYNTH. S D., PIZZO F., VACCARO L. dimethylperhydro-­‐1,3,2-­‐diazaphosphorine y CATAL., vol. supported on polystyrene (PS-­‐BEMP)as an 352; p. 2489-­‐
efficient recoverable an reusable catalyst for 2496, ISSN: the phenolysis of epoxides under solvent-­‐
1615-­‐4150 free conditions A T. ANGELINI , F. FRINGUELLI , D. 4 1 A catalytic approach to the base-­‐promoted Else TETRAHEDRO
S LANARI , PIZZO F:, VACCARO L. reaction of epoxides with activated vier N LETTERS, methylenes vol. 51; p. 1566-­‐1569, ISSN: 0040-­‐
4039 L F. FRINGUELLI, O. PIERMATTI, PIZZO 4 0 Diels-­‐Alder Reactions. STU Science of M F. , VACCARO L. TTG
Synthesis. vol. S ART: 47, p. 561-­‐
Geor
736, g ISBN/ISSN: Thie
978-­‐3-­‐13-­‐
me 147291-­‐ Verl
2012 2011 5,25
0 2011 2011 3,32
9 3,43
4 2011 6,04
8 2011 4,04
7 2011 3,32
9 2011 significativa 6,32
0 2011 5,41
5 2011 3,32
9 2011 -­‐ 2011 2010 5,25
0 2010 5,61
9 2010 2,53
8 2010 -­‐ 112 -­‐ 563 A F.FRINGUELLI, D.LANARI, PIZZO F., L. S VACCARO 4 564 R Vaccaro L. I 565 A FRINGUELLI F, LANARI D, PIZZO F, S VACCARO L. Nominated by the Italian Chemical Society as representative for the EUCHEM Organic Division Young Investigator's Workshop in Regensburg, D, 27-­‐29th/08/2010. 4 0 Solid-­‐Supported Ammonium Fluorides in Bent Organic Synthesis. ham Scie
nce 566 L LANARI D, VACCARO L. 2 M
N A VACCARO L., BALLINI R, BARBONI L, 7 S CASTRICA L, FRINGUELLI F, LANARI D, PIZZO F 0 Critical Surveys Covering the Year 2008 SCI 1 Polystyryl-­‐BEMP as an Efficient Recyclable Catalyst for the Nucleophilic Addition of Nitroalkanes to a,b-­‐Unsaturated Carbonyl Compounds under Solvent-­‐Free Conditions Wile
y 568 A VACCARO L., BALLINI R, BARBONI L, 7 S CASTRICA L, FRINGUELLI F, LANARI D, PIZZO F 1 Polystyryl-­‐BEMP as an Efficient Recyclable Catalyst for the Nucleophilic Addition of Nitroalkanes to a,b-­‐Unsaturated Carbonyl Compounds under Solvent-­‐Free Conditions Wile
y 569 A VACCARO L., BALLINI R, BOSICA G, S PALMIERI A, PIZZO, F 5 0 Isolute Si-­‐carbonate catalyzes the nitronate addition to both aldehydes and electron-­‐
poor alkenes under solvent-­‐free conditions RSC 570 A VACCARO L., BONOLLO S, S FRINGUELLI F, PIZZO F 4 1 Zn(II)-­‐Catalyzed Desymmetrization of meso-­‐
Epoxides by Aromatic Amines in Water 571 A VACCARO L., CASTRICA L, S FRINGUELLI F, PIZZO F 4 1 Catalyst-­‐ and solvent-­‐free conditions as an environmentally benign approach to 4-­‐aryl-­‐
3-­‐cyano-­‐hexahydro-­‐4H-­‐1,2-­‐benzoxazine-­‐2-­‐
oxides Thie
me Stutt
gart RSC 572 A VACCARO L., CASTRICA L, S FRINGUELLI F, PIZZO F 4 1 Enantioselective Michael Addition of Dimethyl Malonate to (E)-­‐beta-­‐Nitrostyrenes Catalyzed by Cinchona Alkaloids under Solvent-­‐Free Condition 573 A VACCARO L., FRINGUELLI F, LANARI S D, PIZZO F 4 0 Amberlite IRA900F as a Solid Fluoride Source Wile
for a Variety of Organic Transformations y under Solvent-­‐Free Conditions 574 B Imbergamo E., Vaccaro L., V B Imbergamo E., Vaccaro L., V titolo "GUIDA DI LUCE", Numero di domanda di brevetto RM2012A000387; titolo "SISTEMA D'ILLUMINAZIONE A LUCE SOLARE PER MEZZI DI TRASPORTO" Numero di domanda di brevetto RM2012A000387 567 575 0 An E-­‐factor minimized protocol for the preparation of metyl b-­‐hydroxy esters ag KG, RSC GREEN 2010 CHEMISTRY; p. 1301-­‐1305, ISSN: 1463-­‐
9262 2010 5,47
2 CURRENT ORGANIC SYNTHESIS, vol. 6; p. 203-­‐
218, ISSN: 1570-­‐1794 2009 2,61 2009 -­‐ 2008 2,61 2008 5,61
9 2008 5,83
6 2008 2,65
9 2008 5,83
6 2008 0.91
5 2008 3,01
6 ADVANCED SYNTHESIS & CATALYSIS, vol. 350; p. 1218-­‐1224, ISSN: 1615-­‐
4150 ADVANCED SYNTHESIS & CATALYSIS, vol. 350; p. 1218-­‐1224, ISSN: 1615-­‐
4150 GREEN CHEMISTRY, vol. 10; p. 541-­‐
544, ISSN: 1463-­‐9262 SYNLETT; p. 1574-­‐1578, ISSN: 0936-­‐
5214 GREEN CHEMISTRY, vol. 10; p. 327-­‐
332, ISSN: 1463-­‐9262 LETTERS IN ORGANIC CHEMISTRY, vol. 5; p. 602-­‐
606, ISSN: 1570-­‐1786 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; p. 3928-­‐3932, ISSN: 1434-­‐
193X 2012 2012 Bent ham Scie
nce 113 Pubblicazioni Altri Membri Produzione scientifica dei membri del Collegio degli ultimi 5 anni (dal 2008 al 2012) (altri membri del Collegio eccedenti i 16 membri di riferimento) Indicare esclusivamente n.5 pubblicazioni significative per membro. Le pubblicazioni comuni a più autori appartenenti al collegio dovranno essere ripetute. Elencare le pubblicazioni secondo il seguente schema: numero progressivo Tipologia (vedi elenco codici) Ayroldi Emira 1 AS 2 3 AS Autori Ayroldi E, Cannarile L, Migliorati G, Nocentini G, Delfino DV, Riccardi C. Ayroldi E, Bastianelli A, Cannarile L, Petrillo MG, Delfino DV, Fierabracci A. AS Fierabracci A, Ayroldi E.. 4 5 AS AS Titolo Casa Editrice Collana Mechanisms of the anti-­‐
inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways A pathogenetic approach to autoimmune skin disease therapy: psoriasis and biological drugs, unresolved issues, and future directions. Experimental strategies in autoimmunity: antagonists of cytokines and their receptors, nanocarriers, inhibitors of immunoproteasome, leukocyte migration and protein kinases Glucocorticoid-­‐Induced TNFR family Related gene (GITR) enhances dendritic cell activity ELSEVIER SCIENCE INC Ronchetti S, Nocentini G, Petrillo MG, Bianchini R, Sportoletti P, Bastianelli A, Ayroldi EM, Riccardi C. Ayroldi E, Riccardi C. Glucocorticoid-­‐induced leucine zipper (GILZ): a new important mediator of glucocorticoid action. An
no FASEB J. Dec;26(12):4805-­‐
20. BENTHAM SCIENCE PUBL LTD BENTHAM SCIENCE PUBL LTD ELSEVIER SCIENCE BV Rivista 20
11 Curr Pharm Des. 17(29):3176-­‐90 20
11 Curr Pharm Des.;17(29):3094-­‐10 Immunol Lett. 135(1-­‐2):24-­‐
33 FEDERATION AMER SOC EXP BIOL 20
12 FASEB J. 23(11):3649-­‐58 20
11 20
09 Biffi Alessandra 6 7 8 AS AS AS Capotondo A., Milazzo R., Politi L.S., Quattrini A., Palini A., Plati T., Merella S., Nonis A., di Serio C., Montini E., Naldini L., Biffi A.). Brain conditioning is National instrumental for successful Academy microglia reconstitution Sciences following hematopoietic stem cell transplantation. Biffi A., Bartolomae C.C., Cesana D., Cartier N., Aubourg P., Ranzani M., Cesani M., Benedicenti F., Plati T., Rubagotti E., Merella S., Capotondo A., Sgualdino J., Zanetti G., von Kalle C., Schmidt M., Naldini L., Montini E. Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection Visigalli I., Delai S., Politi L.S., Di Domenico C., Cerri F., Mrak E., D’Isa R., Ungaro D., Stok M., Sanvito F., Mariani E., Gene therapy augments the AMER SOC HEMATOLOGY efficacy of hematopoietic cell transplantation and fully corrects Mucopolysaccharidosistype I of 20
12 PNAS, 109(37):15018-­‐23 AMER SOC HEMATOLOGY 20
11 Blood, 117(20):5332-­‐9. Blood, 116(24):5130-­‐9. 114 20
10 9 10 AS AS Staszewsky L., Godi C., Russo I., Cecere F, del Carro U., Rubinacci A., Brambilla R., Quattrini A., Di Natale P., Ponder K., Naldini L., Biffi A. ( phenotype in the mouse model. Gentner B., Visigalli I. Hiramatsu H., Lechman E., Ungari S., Giustacchini A., Schira G, Amendola M., Quattrini A., Martino S., Orlacchio A., Dick Identification of BIOMED Hematopoietic Stem Cell-­‐ CENTRAL LTD specific miRNAs Enables Gene Therapy of Globoid Leukodystrophy. Cesani M., Capotondo A., Plati T., Sergi Sergi L., Fumagalli F., Roncarolo M.G., Naldini L., Comi G., Sessa M., Biffi A. Characterization of new WILEY-­‐
Arylsulfatase A gene BLACKWELL mutations reinforces genotype-­‐phenotype correlation inMetachromatic Leukodystrophy. Glucocorticoid induced leucine zipper (GILZ) over –
expression in T lymphocytes inhibitsinflammation and tissue damage in spnal cord injury. Glucocorticoid-­‐induced activation of caspase-­‐8 protects the glucocorticoid-­‐
induced protein Gilz from proteasomal degradation and induces its binding to Sumo-­‐1 in murine thymocytes Glucocorticoid-­‐Induced Leucine Zipper (GILZ) and Long GILZ Inhibit Myogenic Differentiation and Mediate Anti-­‐myogenic Effects of Glucocorticoids . Silymarin suppress CD4+ T cell activation and proliferation: Effects on NF-­‐
kB activity and IL-­‐2 production Peroxisome Proliferator-­‐
Activated Receptor-­‐alpha Contributes to the Anti-­‐
Inflammatory Activity of Glucocorticoids 20
10 Science Transl 2(58):54ra84 Med, Human Mutation 30(10): 20
09 Bruscoli Stefano 11 12 AS AS 13 AS 14 AS 15 AS E. Esposito*, BRUSCOLI S.*, E. Mazzon, I. Paterniti, M. Coppo, E. Velardi, S. Cuzzocrea, C. Riccardi D. DELFINO, SPINICELLI S, POZZESI N, PIERANGELI S, VELARDI E, BRUSCOLI S., MARTELLI MP, PETTIROSSI V, FALCHI L, KANG TB, RICCARDI C., BRUSCOLI S., Donato V., Velardi E., Di Sante M., Migliorati G., Donato R.F., Riccardi C. Gharagozloo M., Velardi E., BRUSCOLI S., Agostini M., Di Sante M., Donato V., Amirghofran Z., Riccardi C. Cuzzocrea S.*, BRUSCOLI S.*, Mazzon E., Crisafulli C., Donato V., Di Paola R., Velardi E., Esposito E., Nocentini G., Riccardi C... SPRINGER 20
12 NEUROTHERAPEUTICS, vol. 9; p. 210-­‐215, NATURE PUBLISHING GROUP 20
11 CELL DEATH AND DIFFERENTIATION vol. 18; p. 183-­‐190, ISSN: 1350-­‐9047 AMER SOC BIOCHEMISTR
Y MOLECULAR BIOLOGY INC 20
THE JOURNAL OF 10 BIOLOGICAL CHEMISTRY, vol. 285; p. 10385-­‐10396, ISSN: 0021-­‐9258 ACADEMIC PRESS LTD-­‐ ELSEVIER SCIENCE LTD 20
10 PHARMACOLOGICAL RESEARCH, vol. 61; p. 405-­‐
409, ISSN: 1043-­‐6618 AMER SOC PHARMACOLO
GY EXPERIMENTA
L THERAPEUTIC
S MOLECULAR 20
PHARMACOLOGY, vol. 73; p. 08 323-­‐337 Nuclear ribosomal internal NATL ACAD transcribed spacer (ITS) SCIENCES region as a universal DNA barcode marker for Fungi 20
12 Cardinali Gianluigi 16 AS Schoch, C. L., K. A. Seifert, S. Huhndorf, V. Robert, J. L. Spouge, C. A. Levesque, W. Chen and K. V. Elena Bolchacova5, Pedro W. Crous4, Andrew N. Miller7, Michael J. Wingfield8, M. Catherine Aime9, Kwang-­‐Deuk An10, Feng-­‐Yan Bai11, Robert W. Barreto12, Dominik Begerow13, Marie-­‐
Proc Natl Acad Sci U S A 109. 115 Josée Bergeron14, Meredith Blackwell15, Teun Boekhout4,16, Mesfin Bogale17, Nattawut Boonyuen18, Ana R. Burgaz19, Bart Buyck20, Lei Cai11, Qing Cai21, G. Cardinali22, Priscila Chaverri23, Brian J. Coppins24, Ana Crespo25, Paloma Cubas25, Craig Cummings5, Ulrike Damm4, Z. Wilhelm de Beer8, G. Sybren de Hoog4, Ruth Del-­‐
Prado25, Bryn Dentinger26,57, Javier Diéguez-­‐Uribeondo27, Pradeep K. Divakar25, Brian Douglas28, Margarita Dueñas27, Tuan A. Duong29, Ursula Eberhardt4, Joan E. Edwards28, Mostafa S. Elshahed30, Katerina Fliegerova31, Manohar Furtado5, Miguel A. García27, Zai-­‐Wei Ge22, Gareth W. Griffith28, K. Griffiths32, Johannes Z. Groenewald4, Marizeth Groenewald4, Martin Grube33, Marieka Gryzenhout34, Liang-­‐
Dong Guo11, Ferry Hagen4, Sarah Hambleton2, Richard C. Hamelin14, Karen Hansen35, Paul Harrold24, Gregory Heller9, Cesar Herrera23, Kazuyuki Hirayama36, Yuuri Hirooka23, Hsiao-­‐Man Ho37, Kerstin Hoffmann6, Valérie Hofstetter38, Filip Högnabba39, Peter M. Hollingsworth24, Seung-­‐
Beom Hong40, Kentaro Hosaka41, Jos Houbraken4, Karen Hughes42, Seppo Huhtinen43, Kevin D. Hyde44,45, Timothy James46, Eric M. Johnson71, Joan E. Johnson28, Peter R. Johnston47, E.B. Gareth Jones18, Laura J. Kelly24,26, Paul M. Kirk48, Dániel G. Knapp49, Urmas Kõljalg50, Gábor M. Kovács49, Cletus P. Kurtzman51, Sara Landvik52, Steven D. Leavitt3, Audra S. Liggenstoffer30, Kare Liimatainen53, Lorenzo Lombard4, J. Jennifer 116 Luangsa-­‐ard18, H. Thorsten Lumbsch3, Harinad Maganti54, Sajeewa S. N. Maharachchikumbura44
, María P. Martin27, Tom W. May32, Alistair R. McTaggart9, Andrew S. Methven55, Wieland Meyer56, Jean-­‐Marc Moncalvo57, Suchada Mongkolsamrit18, László G. Nagy58, R. Henrik Nilsson59, Tuula Niskanen53, Ildikó Nyilasi58, Gen Okada10, Izumi Okane60, Ibai Olariaga35, Jürgen Otte61, Tamás Papp58, Duckchul Park47, Tamás Petkovits58, Raquel Pino-­‐Bodas27, William Quaedvlieg4, Huzefa A. Raja62, Dirk Redecker63, Tara L. Rintoul2, Constantino Ruibal25, Jullie M. Sarmiento-­‐Ramírez27, Imke Schmitt61, 64, Arthur Schüßler65, Carol Shearer66, Kozue Sotome67, Franck O.P. Stefani32, Soili Stenroos39, Benjamin Stielow4, Herbert Stockinger63, Satinee Suetrong18, Sung-­‐Oui Suh68, Gi-­‐Ho Sung69, Motofumi Suzuki10, Kazuaki Tanaka36, Leho Tedersoo70, M. Teresa Telleria26, Eric Tretter71, Wendy A. Untereiner17, Hector Urbina15, Csaba Vágvölgyi58, Agathe Vialle14, Thuy Duong Vu4, Grit Walther4, Qi-­‐
Ming Wang11, Yan Wang71, Bevan S. Weir47, Michael Weiß72, Merlin M. White71, Jianping Xu54, Rebecca Yahr24, Zhu L. Yang21, Andrey Yurkov13, Juan-­‐Carlos Zamora27, Ning Zhang73, Wen-­‐Ying Zhuang11 and David Schindel74 (2012). " 17 18 AS AS Comparison of molecular Del Bove, M., M. and metabolomic methods Lattanzi, P. Rellini, C. as characterization tools of Pelliccia, F. Fatichenti Debaryomyces hansenii and G. Cardinali cheese isolates. Corte, L., L. Roscini, C. Effect of pH on potassium Zadra, L. Antonielli, B. metabisulphite biocidic Tancini, A. Magini, C. activity against yeast and Emiliani and G. Cardinali human cell cultures." ACADEMIC PRESS LTD-­‐ ELSEVIER SCIENCE LTD Food Microbiol 26(5): 453-­‐
459 ELSEVIER SCI LTD 20
12 Food Chemistry 1327-­‐1336 134(3): 117 20
09 19 AS 20 AS Corte, L., L. Antonielli, L. Influence of cell parameters Roscini, F. Fatichenti in Fourier transform infrared and G. Cardinali spectroscopy analysis of whole yeast cells Development of a novel, Corte, L., P. Rellini, L. FTIR (Fourier Transform Roscini, F. Fatichenti InfraRed spectroscopy) and G. Cardinali. based, yeast bioassay for toxicity testing and stress response study ROYAL SOC CHEMISTRY ELSEVIER SCIENCE BV Analyst 136(11): 2339-­‐2349. 20
11 20
10 Analytical Chimica 659(1-­‐2): 258-­‐265 Acta Corazzi Lanfranco 21 22 23 24 25 As AS Macchioni L., Davidescu M., Mannucci R., Francescangeli E., Nicoletti I., Roberti R., Corazzi L. Minelli A., Grottelli S., Corazzi L., Bellezza I., Rambotti M.G., Emiliani C., Fredholm B.B. Susta F., Chiasserini D., Fettucciari K., Orvietani L., Quotadamo F., Noce R., Bartoli A., Marconi P., Corazzi L. and Binaglia L. Buratta M., Castigli E., Sciaccalunga M., Pellegrino RM., Spinozzi F., Roberti R. and Corazzi L H2O2 disposal in cardiolipin-­‐ Elsevier Pub. enriched mitochondria is due Co. to increased cytochrome c peroxidase activity. Adenosine A1 receptors ELSEVIER SCI contribute to mitochondria LTD vulnerability to pro-­‐oxidant stressors Protein expression changes WILEY-­‐
induced in murine peritoneal BLACKWELL macrophages by Group B Streptococcus. BBA-­‐Mol Cell Biol Lip, 1811: 203-­‐208 20
10 Mitochondri 10:369-­‐379 20
10 Proteomics 10:2099-­‐2112 20
12 Loss of cardiolipin in palmitate-­‐treated GL15 glioblastoma cells favors cytochrome c release from mitochondria leading to apoptosis Goretti M., Turchetti B., In vitro antimycotic activity Buratta M., Branda E., of a Williopsis saturnus killer Corazzi L., Vaughan-­‐ protein against food spoilage Martini A. and Buzzini P yeasts WILEY-­‐
BLACKWELL J. Neurochem 105(3):1019-­‐31 20
08 ELSEVIER SCIENCE BV Int J Food Microbiol. 131 (2-­‐ 20
3): 178-­‐82 09 D'Arco G., Blasi F., Cossignani L., Di Giacomo F., Ciavardelli D., Ventura F., Scipioni S.,Simonetti M.S., Damiani P. Blasi F., Dominici L., Moretti M., Villarini M., Maurelli S., Simonetti M.S., Damiani P., Cossignani L. Giuffrida D., Salvo F., Salvo A., Cossignani L., Dugo G. WILEY-­‐
BLACKWELL JOURNAL OF THE SCIENCE 20
OF FOOD AND 12 AGRICULTURE (ISSN:1097-­‐
0010) p. 952 -­‐ 959 Vol. 92 WILEY-­‐
BLACKWELL EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY (ISSN:1438-­‐
9312) p. 1016 -­‐ 1024 Vol. 114 FOOD CHEMISTRY (ISSN:0308-­‐8146) p. 1119 -­‐ 1123 Vol. 124 Cossignani Lina 26 AS 27 AS 28 AS 29 AS Olivotto I., Di Stefano M., Rosetti S., Cossignani L., Pugnaloni A., Giantomassi F., Carnevali O. 30 AS Blasi F., Montesano D., De Angelis M., Maurizi A., Ventura F., Cossignani L., Simonetti M.S., Damiani P. Composition of meat and offal from weaned and fattened rabbits and results of stereospecific analysis of triacylglycerols and phosphatidylcholines In vitro genotoxicity/antigenotoxicit
y testing of someconjugated linoleic acid isomers using comet assay Pigments profile in monovarietal virgin olive oils from various Italian olive varieties Live prey enrichment, with particular emphasis on HUFAs, as limiting factor in false percula clownfish (Amphiprion ocellaris, Pomacentridae) larval development and metamorphosis: Molecular and biochemical implications Results of stereospecific analysis of triacylglycerol fraction from donkey, cow, ewe, goat and buffalo milk ELSEVIER SCI LTD Elsevier Science 20
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COMPARATIVE 11 BIOCHEMISTRY AND PHYSIOLOGY. PART A, MOLECULAR & INTEGRATIVE PHYSIOLOGY (ISSN:1095-­‐6433) p. 207 -­‐ 218 Vol. 159 ACADEMIC PRESS INC ELSEVIER SCIENCE JOURNAL OF FOOD 20
COMPOSITION AND 08 ANALYSIS (ISSN:0889-­‐1575) p. 1 -­‐ 7 Vol. 21 118 20
12 D’Angelo Francesco 31 32 33 AS AS AS Lizundia E., Sarasua J.R., D’angelo F., Orlacchio A., Martino S., Kenny J.M,Armentano I. (2012) Martino S., Tiribuzi R., Ceraci E., Makrypidi G., D'Angelo F., Di Girolamo I., Gritti A., Cusella de Angelis M.G., Papaccio G.P., Sampaolesi M., Berardi A.C., Datti A., Orlacchio A. ( Fortunati E., D’Angelo F., Martino S., Orlacchio A., Kennyhttp://www.
Biocompatible Poly (L-­‐ Wiley Online library lactide) / MWCNT nanocomposites: morphological characterization, electrical properties and stem cell interaction. Coordinated Involvement of Cathepsins S, D and Cystatin C in the Commitment of Hematopoietic Stem Cells to Dendritic Cells Elsevier 20
12 Macromolecular Bioscience. 12(7):870-­‐81. 20
11 The International Journal Of Biochemistry & Cell Biology; 43:775-­‐83 Carbon nanotubes and silver Elsevier nanoparticles for multifunctional conductive biopolymer composites.. sciencedirect.co
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10 130 Libro o Mono-­‐grafia Articoli ELENCO CODICI a contenuto scientifico pubblicato in lingua straniera da casa editrice straniera a contenuto scientifico pubblicato da casa editrice nazionale (sia in italiano che in altre lingue) a contenuto scientifico pubblicato da casa editrice regionale o locale (sia in italiano che in altre lingue) Articolo in lingua straniera su rivista scientifica pubblicata all’estero o in Italia Articolo a contenuto scientifico in libro collettaneo pubblicato da casa editrice straniera Articolo su rivista scientifica e saggio in libro collettaneo a contenuto scientifico, pubblicato in italiano da casa editrice nazionale Articoli saggi Brevetti Brevetti Commenti a sentenze e pronunce, recensioni, relazioni a convegni (solo area 12) Lavori inseriti in atti di convegni (esclusi i pre-­‐prints e gli abstracts), libri divulgativi o a contenuto didattico Riconoscimenti Nazionali Riconoscimenti Internazionali Curatele Riconoscimenti LMS LMN LMR AS ASC ASS BV CC CB RN RI DATA BASE Impact Factor IF Il link dal quale ottenere i valori di IF, http://admin-­‐apps.webofknowledge.com/JCR/JCR?RQ=HOME nel caso di collegamento non funzionante selezionare establish a new session nella pagina visualizzata. Di seguito viene riportato un esempio di come può essere fatta l’estrazione relativa alla singola rivista (ATTENZIONE -­‐ SELEZIONARE L’ULTIMO ANNO DISPONIBILE): Select a JCR edition and
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131 Autovalutazione (da parte del proponente) del posizionamento del Corso rispetto a corsi di dottorato in settori affini in ambito nazionale Il Dottorato di Ricerca in Biotecnologia è nato per rispondere alla crescente necessità culturale e didattica di formare ricercatori qualificati e capaci di operare in questo specifico settore. Il carattere innovativo del corso di Dottorato è la sua multidisciplinarietà, il suo raccordo con Istituti ed Enti di ricerca privati e pubblici del settore sia Italiani che Stranieri, con l'obiettivo anche di partnership paritetiche e creazione di laboratori congiunti e cofinanziati. Scopo del Dottorato in Biotecnologia è quello di preparare personale altamente qualificato ed in grado di assumere ruoli di responsabilità nell’ ambito di progetti sperimentali di ricerca di base ed applicata ed in tutti i settori che concorrono al trasferimento delle conoscenze biologiche e tecnologiche dal laboratorio di ricerca al mondo del lavoro. Rispetto agli altri dottorati in settori affini, il Dottorato in Biotecnologie offre il vantaggio di coinvolgere numerosi gruppi che svolgono a loro attività nei vari ambiti delle biotecnologie; gli studenti potranno perciò essere coinvolti nella programmazione e realizzazione di progetti di ricerca multidisciplinari. Alcuni componenti il collegio docente fanno parte di Spin Off Universitari e potranno trasferire agli studenti la loro esperienza imprenditoriale. Al dottorato partecipano imprese che operano nel settore e che potranno coinvolgere gli studenti nello sviluppo e l’ottimizzazione di processi produttivi. E’ in atto un processo di internazionalizzazione del dottorato che prevede il coinvolgimento di Università e Centri di Ricerca Europei e il percorso didattico prevede corsi in lingua Inglese. (max 1500 caratteri) Principali Atenei e centri di ricerca internazionali con i quali il collegio mantiene collaborazioni di ricerca (max 5) con esclusione di quelli di cui alla sezione 1 Brunner Tomas Univerisitat Konstanz, Germania Kiemer Alexandra K Universitat des Skarlander Saarbruken Belgio Libeirt Claude Universiteit Gent Samapolesi Maurilio Stem Cell Biology and Embryology Katholieke Universiteit Leuven, Belgio Jurga Stefan NanoBioMed Center Polonia Descrizione della situazione occupazionale dei dottori di ricerca che hanno acquisito il titolo negli ultimi tre anni (facoltativo) (max 1500 caratteri) Esperienze passate di collaborazione in attività di ricerca con le imprese convenzionate e valore aggiunto atteso per il corso di dottorato (Riquadro disponibile solo per i dottorati in convenzione con imprese; max 1500 caratteri) 3. Eventuali curricula 132 Curriculum dottorali afferenti al Corso di dottorato denominazione SSD Macrosettore-­‐ Aree CUN Indicare il peso % interessat concorsuale interessate di ciascuna area i 1) Biotecnologie Mediche 2) Biotecnologie Molecolari e Cellulari 3) Biomateriali e Biodispositivi 4) Biotecnologie Industriali BIO/14 BIO/10 BIO/12 CHIM/06 MED /04 MED/09 MED/16 MED/18 MED/40 MED/42 MED/50 CHIM/02 BIO/14 BIO/10 BIO/11 BIO/04 BIO/05 BIO/15 BIO/09 CHIM/06 MED /04 MED/09 MED/42 MED/50 FIS/03 AGR/16 FIS/01 CHIM/02 BIO/14 BIO/10 BIO/11 CHIM/06 MED /04 FIS/03 CHIM/02 FIS/01 BIO/14 BIO/10 CHIM/10 BIO/11 AGR/16 BIO/05 BIO/15 AGR/13 BIO/19 CHIM/06 MED/42 05/G1 05/E1 05/E1 03/C1 06/A2 06/B1 06/D3 06/C1 06/H1 06/M1 06/N1 03/A2 05/G1 05/E1 05/E2 05/A2 057B1 05/G1 05/D1 03/C1 06/A2 06/B1 06/M1 06/N1 02/B1 07/F2 02/A1 03/A2 05/G1 05/E1 05/G1 03/C1 06/A2 02/B1 03/A2 02/A1 05/G1 05/E1 03/C1 05/E2 07/F2 057B1 05/G1 07/E1 05/I1 03/C1 06/M1 Curriculum in collaborazione con imprese (SI/NO) 06 05 03 57 % 40 % 03 % SI 05 06 03 02 07 65 % 20 % 10 % 3 % 2 % SI 05 06 03 02 15 % 05 % 50 % 30 % SI 05 06 03 02 07 30 % 05 % 30 % 30 % 05 % SI 133 MED/42 FIS/03 06/M1 02/B1 4. Struttura formativa Attività didattica disciplinare e interdisciplinare Insegnamenti ad hoc previsti nell'iter formativo tot CFU n.ro insegnamenti Di cui è prevista verifica finale 9 3 si SI n. ro Di cui è prevista verifica finale 12 2 si Insegnamenti mutuati da corsi di laurea magistrale SI Ogni anno verranno tenuti seminari, tenuti da docenti universitari e/o SI professori a contratto esperti del settore Cicli seminariali Soggiorni di ricerca e/o qualificati ricercatori provenienti dal settore pubblico e privato, che verteranno su argomenti di Biotecnologie inerenti i vari curricula. (opzioni selezionabili anche congiuntamente) SI ITALIA-­‐ al di fuori delle istituzioni coinvolte SI ESTERO nell’ambito delle istituzioni coinvolte SI ESTERO -­‐ al di fuori delle istituzioni coinvolte SI Descrizione delle attività di formazione di cui all’art. 4, comma 1, lett. f) Tipologia della formazione Descrizione sintetica (max 500 caratteri per descrizione) Linguistica Gli studenti frequenteranno corsi presso il Centro Linguistico di Ateneo e corsi di insegnamento e seminari in lingua inglese. Alla fine del dottorato dovranno aver raggiunto il livello B1 Informatica Tutti i dottorandi riceveranno una formazione nel campo della Bioinformatica Gestione della ricerca, della conoscenza dei sistemi di Saranno effettuati corsi di statistica e management ricerca e dei sistemi di finanziamento gestionale e finanziario con l’obiettivo di fornire ai dottorandi le basi per organizzare e gestire progetti di ricerca. Valorizzazione dei risultati della ricerca e della Partecipazione a congressi nazionali e internazionali nei proprietà intellettuale settori del dottorato. Pubblicazioni su riviste internazionali peer-­‐reviewed journals. Uno dei corsi riguarderà il “Diritto dell’innovazione tecnologica” Attività dei dottorandi 134 È previsto che i dottorandi possano svolgere attività di tutorato SI Attività di tutoraggio d’aula e di laboratorio agli studenti dei Corsi di SI laurea (triennale e Magistrali) in Biotecnologie. È previsto che i dottorandi possano svolgere attività di didattica integrativa SI Ore previste SI 12 135 5. Requisiti e modalità di ammissione Requisiti richiesti per l'ammissione Tutte le lauree magistrali NO se non tutte, indicare selezione da elenco classi di laurea magistrale: LM-­‐7 quali: LM-­‐8 LM-­‐9 LM-­‐6 LM-­‐17 LM-­‐18 LM-­‐54 LM-­‐60 LM-­‐41 LM-­‐13 LM-­‐42 Laree vecchio ordinamento rilasciate dalle Facoltà di : Scienze MM FF NN, Farmacia, Medicina e Chirurgia, Medicina Veterinaria, Agraria. Altro per studenti stranieri Eventuali note Il Collegio dei Docenti si preserva la possibilità di ammettere candidati non in possesso dei requisiti sopra indicati ma che dimostrano conoscenze comprovate e approfondite delle tematiche del dottarato e che per il loro specifico profilo professionale consentono di mantenere rapporti con le aziende. (max 500 caratteri) Modalità di ammissione Modalità di ammissione Selezione tra le seguenti opzioni: SI/NO titoli prova scritta SI NO prova orale SI laboratorio NO lingua altro SI NO Per i laureati all’estero la modalità di ammissione NO è diversa da quella dei candidati laureati in Italia? NO se SI specificare (Selezione tra le seguenti opzioni) NO titoli SI/NO prova scritta SI/NO prova orale SI/NO laboratorio SI/NO lingua SI/NO altro SI/NO 136 6. Posti e borse Posti Numero Posti banditi (messi a concorso) Di cui 18 -
Posti banditi con borsa -
Posti coperti da assegni di ricerca -
Posti coperti da contratti di apprendistato -
Eventuali posti senza borsa 6 12 Posti con borsa riservati a laureati in università estere Posti riservati a borsisti di Stati esteri Posti riservati a borsisti in specifici programmi di mobilità internazionale Posti riservati a dipendenti di imprese impegnati in attività di elevata qualificazione (dottorato industriale) Euro Borse Importo della borsa Maggior importo procapite (per posto coperto con borsa) per soggiorni di ricerca all’estero (max 50% borsa) Budget procapite annuo per attività di ricerca in Italia e all’Estero (min 10% importo borsa) Eventuali note (max 500 caratteri) L’importo della borsa di Dottorato sarà in accordo con quanto stabilito dalla Normativa dell’Ateneo di Perugia in merito alle borse di dottorato. 7. Strutture operative e scientifiche Tipologia Descrizione sintetica Laboratori Laboratori di Ricercache che afferiscono ai Dipartimenti coinvolti nel Dottorato di Ricerca in Biotecnologie I dottorandi avranno accesso alle biblioteche dell’Ateneo e degli Enti di Ricerca e Privati che collaborano con il Dottorato di Ricerca. Saranno messe a disposizione le Banche Dati necessarie per il raggiungimento degli obiettivi Biblioteche Banche dati (max 500 caratteri per ogni descrizione) 137 prefissati di ciascuna tesi di dottorato. Ogni dottorando avrà accesso ad almeno 1 computer con collegamento a Internet ed e-­‐mail personale. Computer facilities Altro 8. Finanziatori esterni Finanziatori esterni ITALIANI del corso di dottorato n. Tipologia del soggetto Pubblico/Privato Denominazione del soggetto Finanziatori esterni STRANIERI del corso di dottorato n. Tipologia del Paese Pubblico/Privato soggetto Denominazione del soggetto 138 

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