Vevo 2100 system

Vevo® 2100
Features
v1.2
New and Improved Features
• New Features
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Faster frame rates
Multiple focal zones
Steerable Doppler
Advanced cardiac strain
analysis package
– Color Doppler Mode
– ECG gated acquisition
– Large animal imaging:
rabbit
• Improved features
– Improved Power Doppler
Mode sensitivity
– Faster 3D acquisition
– Software workflow
Vevo 770
Vevo 2100
Mechanical vs. Linear Array
• 1 element
• 1 focal depth
• Lower frame rates, due to
the need to mechanically
scan
• 256 elements
• Dynamic focusing
throughout the entire
image
• Higher frame rates due to
electronic switching of the
elements
• Simultaneous modes
• Doppler Steering
Vevo 770: 707B – 30 Mhz
•Typical frame rate 100 fps
•Max frame rate (1 mm width) 240 fps
Vevo 2100: MS400 – 30 Mhz
•Typical frame rate 300 fps
•Frame rate 500 fps with 4.5 mm FOV
•Max frame rate (2 mm width) 1000 fps
Multiple & Dynamic Focal Zones
Multiple/Dynamic Focal Zones:
Sagittal Profile at E12
Video Loop
Vevo 2100
Multiple/Dynamic Focal Zones:
Midline Abdominal Landmarks
Video Loop
Color Doppler Mode Imaging
Color Doppler Mode:
Mitral Valve Inflow
Vevo 2100
Video Loop
Aortic Arch - Banding
~800 mm/s
~3800 mm/s
Vevo 2100
Kovacs, Washington University
Vevo 2100
Color Doppler:
Spleen
Video Loop
Advanced Strain Analysis
VevoStrain™ Software
Myocardial wall motion tracking
• Enables post-processing quantification of
myocardial wall abnormalities in
circumferential, radial and longitudinal axes
of heart motion
• Velocity • Displacement • Strain • Strain Rate
• All data quantification by point or region
exportable in csv format
Circumferential
• Qualitative analysis by vector and
parametric displays
• Not just speckle tracking:
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–
–
–
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Speckle analysis
Valve plane motion
Spatial coherence
Periodic motion
Border tracking
Radial
Longitudinal
VevoStrain Analysis –
Normal Vs. Infarct
Velocity
Strain Rate
Kovacs, Washington University
ECG-Triggered Acquisition
ECG Gating: Systole/Diastole
Long Axis Diastole
Long Axis Systole
Vevo 2100
Video Loop
Vevo 2100
3D of Heart with ECG Triggering at
End Diastole
Video Loop
3D of Heart with ECG Triggering
Other Array Benefits
Steerable Power and Color Doppler
Steered Power Doppler
in the Kidney
Steered Pulse Wave Doppler
in the aorta
Steered Color Doppler
in the Femoral Artery
Video Loop
Simultaneous Scanning
(B-mode and PW Doppler)
Video Loop
Improved Power Doppler Imaging
Vevo 2100
Acquisition frame rate 27 fps
Vevo770
Acquisition frame rate ~1-2 fps
Vevo 2100 Advantage – faster acquisition frame rate and greater sensitivity
Video Loop
Faster 3D Scanning
• Linear array
technology drastically
reduces the amount
of time is takes to
acquire a 3D Power
Doppler image
• 3D B-mode Imaging
~2x faster
• 3D Power Doppler
Imaging ~10x faster
Nonlinear Contrast Mode
and VevoCQ™ Software
Vevo MicroMarker® Applications
Mouse subcutaneous hind limb model
Image courtesy of Lazar J, SUNY Downstate Medical Center, 2010
Video Loop
Vevo MicroMarker Quantification
User defined regions of interest
Curve fit algorithms
Perfusion Quantification
Selection of VevoCQ bolus perfusion model parametric outputs
Whole Tumor
(green)
Bottom Right
(yellow)
Upper Area
(pink)
Bottom Left
(turquoise)
Peak Enhancement
(a.u.)
29.6
8.2
41.7
8.3
Time to Peak
(sec.)
3.8
3.7
3.7
2.8
Wash-in Rate
(a.u.)
15.5
4.5
22.6
6.1
Parametric images
Peak Enhancement
Time to Peak
Wash-in Rate
Targeted Microbubble Ultrasound
VEGFR2
Isotype Control
Mouse subcutaneous hind limb model
Targeted Biomarker Quantification
User defined regions of interest
Curve fit algorithms
Targeted Biomarker Quantification
VevoCQ software differential targeted enhancement parametric output
Whole
Tumor
(Green)
Left Area
(Yellow)
Right Area
(Pink)
VEGFR2
7.56
10.00
5.79
Isotype Control
1.47
2.08
1.08
Parametric images
VEGFR2
Isotype Control
Transducer MS220:
For Larger Targets and Animals
15 MHz Transducer MS200:
Rabbit Heart
3kg Rabbit
Video Loop
Software Improvements
Study Management
Image of split screen
Summary
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Linear array probe
Faster frame rate
Multiple focal zones
Nonlinear Contrast
Steerable Doppler
Advanced cardiac strain
analysis package
Color Doppler Mode
ECG gated acquisition
3D Cardiac Imaging
Improved Power Doppler
Mode sensitivity
Faster 3D acquisition
Large rat and rabbit
imaging
Vevo 770
Vevo 2100
www.visualsonics.com
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The netherlands
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VisualSonics, VisualSonics logo, VisualSonics dot design, Vevo, Vevo MicroMarker, VevoStrain, VevoCQ, SoniGene, RMV, EKV, MicroScan, LAZRTight, Insight through In Vivo Imaging, are
registered trademarks (in some jurisdictions) or unregistered trademarks of VisualSonics Inc.
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