East Netherlands - Oost NV | East Netherlands Development Agency
Transcription
East Netherlands - Oost NV | East Netherlands Development Agency
Sector Profile High Tech: Nano Technology East Netherlands 2013/2014 version3 Albert Hoogeveen East Netherlands Development Agency P.O. Box 5518 NL-7500 GM Enschede Telephone + 31 (0) 53 851 68 51 E-mail [email protected] Internet www.oostnv.nl July, 2013 © Oost NV The East Netherlands Development Agency (Oost NV) has provided the information contained herein for the sole use of our client. We request that it be used for information purposes only, and not be copied, reproduced, or in any other form distributed, either in part or in whole, without the express written consent of Oost NV. Oost NV assumes no direct or implied liability for the information contained herein Welcome to the Nanotechnology hot spot- East Netherlands East Netherlands is a dynamic environment in which to start or grow your high tech business. We are pleased to present a collection of profiles that demonstrates the best of what this region has to offer when it comes to nanotechnology research, engineering and business. There are few places in the world that combine such an established and reputable scientific environment, an energizing and technologically driven business climate, and a unique combination of nature, history, and culture that guarantees an outstanding quality of life. Part One of this report presents universities, research institutes, programs and networks in the field of nanotechnology. Part Two of this report provides more general information about East Netherlands. We invite you to see for yourself how your company can benefit from such a technologically innovative environment. It would be our pleasure to be your host and show you the best of what East Netherlands has to offer. Yours sincerely, Foreign Investments Senior Project Manager A. Hoogeveen MBA 2 Factsheet: Nano Technology in East Netherlands Introduction East Netherlands is the place where science meets business. East Netherlands is the breeding ground of many initiatives in the field of nanotechnology. East Netherlands is home to one of the leading knowledge institutes in nanotechnology in the world, called MESA+. In addition many other education programs and research institutes in nanotechnology are located in East Netherlands. Oost NV, the East Netherlands Development Agency, is strongly supporting the initiatives geared towards nanotechnology and is closely working together with MESA+ and other parties on the various initiatives in the Netherlands. Universities University of Twente: # 1 in IT Wageningen University (food, animal, environment, agrotechnological sciences) Radboud University Nijmegen (a.o. University Medical Centre St. Radboud) Nanotechnology Related Research Institutes MESA+. The institute employs 500 scientists, of which 275 PhD students and postdocs. MESA+ strategic research orientations are BioNanotechnology, Cell-Stress, MesoFluidics, NanoElectronics, NanoFibrication and Molecular Photonics. Institute for Molecules and Materials. Fundamental and application-oriented research in the field of molecular functional structures and functional materials of nanometer dimensions. Top Institute Food and Nutrition. Scientific breakthroughs in food and nutrition, resulting in the development of innovative products and technologies that respond to consumer demands for safe, tasty and healthy foods. Plant Research International. Strategic and applied research in genetics and reproduction, genomics, proteomics, metabolomics, bioinformatics, crop protection, crop ecology and agrosystems. The Wageningen Bionanotechnology Centre is active in the fundamental science and technology of micro- and nanosystems and their applications in food and health. The High Field Magnetic Laboratory is committed to research in the highest available magnetic fields. 33T magnets are available, a 38T resistive magnet and a 45T hybrid magnet are under development NanoLab Nijmegen makes new developments in nanotechnology, in particular Scanning Probe Microscopy, accessible for small-and medium-sized companies. High Tech Factory is a shared production facility for products based on microsystems and nanotechnology. Nanotechnology Programs & Projects High Tech Factory is the latest production location partnered with the MESA+ Institute for Nanotechnology at the University of Twente. High Tech Factory offers companies space, facilities and high-value cleanrooms. In addition, entrepreneurs have available to them the possibility to apply for funding: the High Tech Fund. TOP program. With providing knowledge and financing, this program for students and staff of the University of Twente can be credited for the launching of many new products and businesses in the market. NanoNextNL is a consortium of more than one hundred companies, universities, knowledge institutes and university medical centres, which is aimed at research into micro and nanotechnology NanoLabNL is a Dutch national facility for nanotechnology research. NanoLabNL offers the use of their facilities and expertise to universities, research institutes, start-ups and industry. Companies with a Focus on Nanotechnology EastNetherlands hosts many nanotechnology related companies like NXP, Sensata, PANalytical, Micronit, Nanomi, Nanosens, Pentair (Norit), Thales, SenzAir and many others. East Netherlands is the #1 location for companies and research institutes in nanotechnology. 3 Fact Sheet: East Netherlands General East Netherlands, formed by the provinces of Gelderland and Overijssel, is located on the German border and is situated on major European highways. Highway A1 for example links Western Netherlands to Northern and Eastern Europe and intersects the region. Highway A12 and A15 connects the Netherlands with the Ruhr-area (Germany). Traffic density is relatively light: traffic flows freely. East Netherlands has more than 3,000,000 inhabitants. Major cities are Apeldoorn, Arnhem, Ede, Enschede, Nijmegen and Zwolle (more than 100,000 inhabitants). Airport Amsterdam is just a one to two hour drive from East Netherlands, also reachable by direct train links. Airport Münster-Osnabrück (Germany) is only 44 miles from Enschede. Airport Düsseldorf is approximately 72 miles from Nijmegen. Attractive cost base - Low cost structure - Affordable office and distribution space Personnel in East Netherlands Large pool of qualified people - Relatively easy to attract personnel - Lower wages compared with many other regions in Europe - Multi-lingual - Highly productive - Strong work ethic - International experience and outlook Flexible - 24 hour / 7 days per week if needed Education - Highly educated workforce World-class universities Technical University of Twente, Enschede Wageningen University (food, animal, environment, agrotechnological sciences) Radboud University Nijmegen (a.o. University Medical Centre St. Radboud) Many Universities of Professional Education Standard of living Beautiful green surroundings and plenty of open space to work, live, and play. Several large nature parks and many historical villages. Relatively low site and construction costs. East-Netherlands has leading medical facilities. East-Netherlands has low crime-rates and a high level of satisfaction with city fire and police services. 4 Table of Content Welcome to the Nanotechnology hot spot- East Netherlands ................................................................ 2 Factsheet: Nano Technology in East Netherlands .................................................................................. 3 Fact Sheet: East Netherlands.................................................................................................................. 4 Part 1: Nano Technology in East Netherlands Universities University of Twente ................................................................................................................................ 9 Radboud University Nijmegen ............................................................................................................... 11 Wageningen University and Research Centre ...................................................................................... 12 Related Research Institutes MESA+ Institute for Nanotechnology .................................................................................................... 13 Institute for Molecules and Materials ..................................................................................................... 15 Top Institute Food and Nutrition ............................................................................................................ 16 Plant Research International ................................................................................................................. 18 Wageningen BioNanotechnology Centre .............................................................................................. 19 High Field Magnet Laboratory (HFML) .................................................................................................. 20 NanoLab Nijmegen ................................................................................................................................ 21 High Tech Factory ................................................................................................................................. 22 Programs & Projects Top Program Overijssel: Support for Entrepreneurs Top Placement................................................... 23 NanonextNL ........................................................................................................................................... 24 VentureLab International & Soft Landing .............................................................................................. 24 UT International Ventures ...................................................................................................................... 26 Networks Kennispark Twente: an innovative place for knowledge-intensive companies ..................................... 27 Technology Circle Twente (TKT) ........................................................................................................... 28 MinacNed............................................................................................................................................... 29 Locations Kennispark Innovation Campus............................................................................................................. 30 Mercator Technology & Science Park ................................................................................................... 32 Company Profiles 3T ........................................................................................................................................................... 34 Aquamarijn Micro Filtration .................................................................................................................... 34 AeroTech Development ......................................................................................................................... 35 Blue4Green............................................................................................................................................ 35 Bronkhorst High-Tech............................................................................................................................ 36 5 Cameron Health .................................................................................................................................... 36 Dannalab ............................................................................................................................................... 37 Delta Mask ............................................................................................................................................. 37 Demcon ................................................................................................................................................. 38 eMALDI .................................................................................................................................................. 38 Encapson ............................................................................................................................................... 39 IBIS Technologies ................................................................................................................................. 39 IMS ........................................................................................................................................................ 40 Inertia ..................................................................................................................................................... 40 LioniX ..................................................................................................................................................... 41 MASER Engineering .............................................................................................................................. 41 Medimate ............................................................................................................................................... 42 Medspray ............................................................................................................................................... 42 MicroCreate ........................................................................................................................................... 43 Microflown Technologies ....................................................................................................................... 43 Micronit .................................................................................................................................................. 44 Mosaic Systems .................................................................................................................................... 45 MyLife Technologies .............................................................................................................................. 45 Nanomi .................................................................................................................................................. 46 NanoPhysics .......................................................................................................................................... 46 Nanosens............................................................................................................................................... 47 NXP ....................................................................................................................................................... 47 Nymus 3D .............................................................................................................................................. 48 Optisense............................................................................................................................................... 48 Ostendum .............................................................................................................................................. 49 PANalytical ............................................................................................................................................ 49 Pentair X-Flow (former Norit X-Flow) .................................................................................................... 50 PhoeniX software .................................................................................................................................. 50 Relitech .................................................................................................................................................. 51 Satrax .................................................................................................................................................... 51 Sensata Technologies Holland .............................................................................................................. 52 Sentron Europe ..................................................................................................................................... 52 SenzAir .................................................................................................................................................. 53 SmartTip ................................................................................................................................................ 53 SolMateS ............................................................................................................................................... 54 Tide Microfluidics ................................................................................................................................... 54 Thales Nederland .................................................................................................................................. 55 Twente Solid State Technology (TSST) ................................................................................................ 55 U-Needle................................................................................................................................................ 56 VDL Enabling Technologies Group ....................................................................................................... 56 WieWeb Software .................................................................................................................................. 57 XiO Photonics ........................................................................................................................................ 57 6 Part 2: General information East Netherlands East Netherlands in Figures .................................................................................................................. 60 Infrastructure in East Netherlands ......................................................................................................... 61 Economic Structure East-Netherlands .................................................................................................. 65 Office and manufacturing rents in the Netherlands ............................................................................... 66 Number of Students and Graduates in East Netherlands ..................................................................... 67 Unemployment....................................................................................................................................... 68 Labor cost in East-Netherlands ............................................................................................................. 69 East Netherlands Development Agency ................................................................................................ 70 7 Part 1: Nano Technology in East Netherlands 8 Universities University of Twente The University of Twente is a young, entrepreneurial university. It sets standards in the field of new technology and seeks to stimulate change, renewal and progress in society. The university works with the technologies of the future - information technology, biotechnology and nanotechnology - in which behavioural and social science research play a vital role. The University of Twente is active in areas such as health, water, sustainability, security and education. Faculties Behavioral Sciences (BS) School of Management and Governance (SMG) Engineering Technology (CTW) Electrical Engineering, Mathematics and Computer Science (EEMCS) Science and Technology (TNW) International Institute for Geo-Information Science and Earth Observation (ITC) Research The University of Twente’s is accommodated in six successful research institutes. The following matrix displays the interrelation between faculties and institutes. Faculties INSTITUTES MESA MIRA CTIT IGS TNW x x EEMCS x x x CTW x x x x BS x x x SMG x x x x Centre for Telematics and Information Technology Institute for Innovation and Governance studies Institute for Nanotechnology Institute of Mechanics, Processes and Control Twente Institute for Biomedical Technology and Technical Medicine Institute for Behavioral Research The institutes combine scientific excellence with a constant search for real innovation and applications for society, and have successfully instigated many spinoff activities. Science relies on talent, and the UT wants attract that that talent by offering high quality research environments and opportunities for junior and senior researchers. The UT attracts talent through the Graduate School, tenure tracks, and additional space and funding for excellent projects. 9 The University of Twente actively promotes entrepreneurship among its students and staff through various programmes. Kennispark Twente is the main vehicle for the promotion of entrepreneurship and the commercialization of knowledge. In 20 years over 700 companies have originated from the university. Many were launched with the TOP programme (Temporary Entrepreneurial Positions), providing basic funding and coaching. These companies have a 5-year survival rate of over 70%, leading to almost 10,000 jobs to date. Furthermore, the university has about 130 student-run companies. For more information: http://www.utwente.nl/en/ 10 Radboud University Nijmegen Radboud University Nijmegen is one of the leading academic communities in the Netherlands. Established in 1923 and situated in the oldest city of The Netherlands, it has seven faculties and enrols over 19,000 students in 107 study programs (40 Bachelor’s and 67 Master’s programmes). An international dimension is an essential aspect of the quality of the university’s education and its research and is an integral part of the university’s identity. Radboud University Nijmegen´s seven faculties are: Faculty of Philosophy, Theology and Religious Studies Faculty of Arts Faculty of Law Faculty of Social Sciences Faculty of Medical Sciences Faculty of Science Nijmegen School of Management International Relations Radboud University Nijmegen engages in various forms of cooperation in order to develop and strengthen the international character of the university. Staff are internationally orientated and are encouraged to collaborate with partners from abroad. Research The research of Radboud University Nijmegen covers a wide range of disciplines. The university is not only strong in the field of life sciences, but also in law, language, and literature. Its high-quality research institutes, which rank at the forefront of a number of fields, offer unique opportunities to undergraduates, postgraduates and PhD students alike. Research institutes Radboud University has grouped its research within research institutes with the aim of creating an optimal research environment which has good focus and a critical mass. Radboud University has several major research institutes. One of Radboud University’s distinguishing hallmarks its emphasis on interdisciplinarity. The current size of the University and its academic breadth provide the conditions for interdisciplinary cooperation, where new ideas can emerge. For example, at the Nijmegen Centre of Molecular Life Sciences (NCMLS), biomedical experts, medical scientists, biologists, physicists, and bioinformaticians work together. Labs and facilities The numerous labs and facilities are available to students, faculty, staff and researchers throughout the campus and are also available to scientists from outside the university. For more information: www.ru.nl 11 Wageningen University and Research Centre Mission: “To explore the potential of nature to improve the quality of life” Wageningen University and Research Centre (Wageningen UR) provides education and generates knowledge in the field of life sciences and natural resources. The domain of Wageniningen UR consists of three related core areas: Food and food production Living environment Health, lifestyle and livelihood This combination of knowledge and experience enables Wageningen UR with its 6,500 staff and 10,000 students to contribute actively to solving scientific, social and commercial problems in the field of life sciences and natural resources. Wageningen UR approaches these national and international issues from the perspectives of various disciplines, with an integrated approach and in close collaboration with governments, companies, stakeholder organizations, citizens, and other knowledge institutions. Wageningen UR pays attention to the balance between three priorities in society: economics, culture and nature. Wageningen UR has branches all over The Netherlands (and in China and Brazil, by the way). A large number of lecturers, researchers and other employees are based at Wageningen Campus. Research; Areas of expertise Nutrition and health Food production Biobased economy Coast & Sea Nature and landscape Climate and water Market and chain strategies Research Institutes Alterra Central Veterinary Institute Centre for Development Innovation Food & Biobased Research IMARES LEI Livestock Research Applied Plant Research Plant Research International RIKILT Wageningen UR Greenhouse Horticulture The strength of Wageningen UR lies in its ability to join the forces of specialised research institutes and Wageningen University. Education Wageningen University offers scientific education. Students get the opportunity to combine the pure sciences – from plant sciences to food technology and health – with the social sciences – from environmental studies to economics and sociology. For more information: www.wageningenur.nl/uk 12 Related Research Institutes MESA+ Institute for Nanotechnology MESA+ is one of the largest nanotechnology research institutes in the world, delivering competitive and successful high quality research. It uses a unique structure, which unites scientific disciplines, and builds fruitful international cooperation to excel in science and education. MESA+ has created a habitat for start-ups in the micro- and nanoindustry to establish and to mature. MESA+, Institute for Nanotechnology, is part of the University of Twente and cooperates extensively with various research groups within the University. The institute employs 500 people of which 275 are PhD’s or postdocs. With its NanoLab facilities the institute holds 1250 m2 of cleanroom space and state of the art research equipment. MESA+ has an integral turnover of 45 million euro per year of which 60% is acquired in competition from external sources. The structure within MESA+ supports and facilitates the researchers and stimulates cooperation actively. MESA+ combines the disciplines of physics, electrical engineering, chemistry and mathematics. Internationally appealing research is achieved through this multidisciplinary approach. It is strengthening its international academic and industrial network by fruitful cooperation programs. MESA+ focuses on nanotechnology based on its underlying strengths in materials science, microsystem technology, bottom-up chemistry, optics and systems. Its mission is: to excel in its field of science and technology; to educate researchers and designers in the field; to build up fruitful national and international cooperation with industry and fellow institutes. Within MESA+, different faculties combine their strengths within the following disciplines: Electrical Engineering, Mathematics and Computer Science (EEMCS); Sciences and Technology (S&T) Faculty of Management and Governance (FMB: Faculteit voor Management en Bestuur) The MESA+ research programs are directly related to the national research program NanoNed. In NanoNed the importance of a national facility has been acknowledged, and a major part of the effort and the accompanying budget is dedicated to NanoLab NL. NanoLab NL has the aim to build up, maintain and provide a coherent and accessible high-level, state-of-theart infrastructure for nanotechnological research and innovation in the Netherlands. NanoLab NL is about national cohesion in infrastructure, access, and tariff structure. MESA+ is proud to be part of the national consortium NanoLab NL. MESA+ NanoLab plays a central part in collaborations with industry. MESA+ has a strong relationship with industry, both through joint research projects with the larger multinational companies, and through a cooperation policy focused on small and medium- sized enterprises. The Institute maintains an 13 extensive international network. It cooperates and exchanges researchers with other leading international nanotechnology institutes. For more information: www.mesaplus.nl 14 Institute for Molecules and Materials IMM is an interdisciplinary Graduate Research School within the Faculty of Science. Its mission is to conduct research and train graduate students in the design, study, and manipulation of the properties of functional molecules and materials. It organizes the coordinated effort by chemists, physicists and biological chemists of IMM to carry out fundamental and application-oriented research in the field of molecular functional structures and functional materials of nanometer dimensions. IMM is a highly interdisciplinary research institute comprised of 19 research groups active in areas ranging from condensed matter science to (bio)chemical synthesis. The institute has unique experimental facilities. Research Facilities The IMM exhibits a multitude of advanced spectroscopic tools that, on their own, allows for a detailed characterization of molecules and materials in the nano-domain. Yet, real breakthroughs are to be anticipated when such tools are combined to investigate systems simultaneously with respect to different properties. The research facilities at IMM: HFML (director prof. J.C. Maan) NMR (under supervision of prof. A. Kentgens) FELIX, FELICE & FLARE (under supervision of prof. W. van der Zande/dr. L. van der Meer) Nanolab (under supervision of dr. Hans Elemans) Trace Gas Facility (under supervision of dr. Frans Harren) For more information: www.ru.nl/imm 15 Top Institute Food and Nutrition TI Food and Nutrition is a public private partnership of science, industry and government conducting strategic research in food and nutrition. Its partners are key players in the global food industry and include twenty-six leading food and ingredient manufacturers and personal care companies and respected research institutes and universities including medical centres. TI Food and Nutrition also partners in several European research programmes in the areas of food, nutrition and genomics. Its annual turnover is €25 million. TI Food and Nutrition plays a major role in providing its industry partners with leads for the development of new, healthy foods with regard to major health concerns such as obesity and metabolic syndrome. Another focus lies on generating a knowledge base for use in developing fermented foods with improved functionality and which may target microbial activity in the gastrointestinal tract. TI Food and Nutrition is a major player in the Dutch government’s Innovation Areas Programme. The government defined these areas as key for economic growth and investment and has the goal of maintaining and expanding the Netherland’s position as the leading innovation area in food and nutrition. Research The themes of TI’s research include: Nutrition and Health Sensory and Structure Bioingredients and Functionality Cardiovascular Health Functional Fermentation Food Structuring Gastrointestinal Health Food Chain Sustainability and Dynamics Sensory-Liking Food Safety and Preservation Texture-Taste Weight Management Oral Health Muscle Health and Function The three cross-theme platforms are: Nutrigenomics Bacterial Genomics Knowledge Management Partners TI Food and Nutrition industrial partner organizations Cargill CBL Chr. Hansen CRV CSK food enrichment CSM Danone DSM Federatie Nederlandse Levensmiddelen Industrie (FNLI) FrieslandCampina Fromageries Bel GlaxoSmithKline Kellogg Company Nestlé PepsiCo Philips Research Productschap Zuivel Unilever VION Food Group Wrigley 16 TI Food and Nutrition partner research institutes: ACTA Dental Research Groningen University / UMCG Maastricht University / MUMC+ NIZO food research TNO Wageningen University and Research Centre For more information: www.tifn.nl 17 Plant Research International Through the combination of know-how and experience across the entire spectrum of plant research, Plant Research International offers unique new perspectives for governments and private companies, for agriculture and horticulture, and for rural and environmental development. Plant Research International is part of Wageningen University and Research Centre (Wageningen UR). Plant Research International is focused on four important scientific, social and economic themes: Plant-based raw materials Health Sustainable production and climate change Systems biology Innovative Plant Research International offers innovative products: from DNA to complete agricultural production systems. Based upon their wide range of scientific qualities, Plant Research International offers their clients truly unique solutions. World wide Plant Research International’s clients and partners come from all parts of the world. Their products offer competitive advantages, improving the position of companies and enabling governments to further develop and execute policies for a sustainable economy. Research Facilities Unifarm Organic Experimental and Training Farm Droevendaal Laser technique for measuring droplet size spectrum Imspector for mobile measurement of crop characteristics Marker-free technology Spraying laboratory Wageningen Omics Facility For more information: www.pri.wur.nl/uk 18 Wageningen BioNanotechnology Centre The Wageningen Bionanotechnology Centre (BioNT) is active in the fundamental science and technology of micro- and nanosystems and their applications in food and health. The center helps companies to utilize the opportunities of micro- and nanotechnology to improve food and prevent health problems. Research themes Interdisciplinary research teams from Wageningen University & Research Centre closely co-operate on: Chemical biology Consumer Behavior and nano perception Encapsulation and delivery Process innovation Sensors and diagnostics Structure and texture Toxicology and Risk Assessment Micro- and nanotechnology can make important contributions to the fulfilment of these challenges. It will allow sensors and diagnostic systems with improved sensitivity and specificity with which food quality can be assured and processes can be controlled more accurately. Application of micro- and nanotechnology will make separation and other food processes more efficient and will open up possibilities for new products. Derived from drug delivery systems envelopes for the delivery of nutrients can be designed that will improve the uptake by the consumer. Nanoscale control of structures will allow tailoring the texture of food products to the requirements of consumer groups. Results of micro- and nanotechnology will have a large impact on packaging and logistics of food. Although these results are attainable within the foreseeable future, the combined effort of academia, research institutions and industry is required to develop them into economically viable concepts. BioNT, the centre for Applications of Nanotechnology in Food, offers state-of-the art facilities and expertise on the cross-section of micro- and nanotechnology and food to help industry in these efforts. For more information: www.biont.wur.nl/uk 19 High Field Magnet Laboratory (HFML) The HFML is committed to generate the highest available continuous magnetic fields. 33T magnets are available, a 38T resistive magnet and a 45T hybrid magnet are under development. HFML performs research with these fields and makes them available to qualified external users. Local research interests are: Magnet technology Soft condensed matter and molecular material Strongly correlated electron systems and Semiconductors and nano-systems. The HFML is a Large European Research Infrastructure and a Dutch national research facility. It is jointly operated by the Radboud University Nijmegen and the Foundation for Fundamental Research on Matter (FOM). The HFML is part of the Faculty of Science and has close cooperation with the Institute for Molecules and Materials (IMM) and is sponsored by the EU for access of external users. The HFML is an independent research institute with strong scientific relations with the Institute of Molecules and Materials belonging to the Faculty of Science (which includes physics, chemistry, biology, informatics and mathematics departments). The connection to the IMM and the Faculty guarantees the availability of a very wide range of expertise and support in a lively scientific climate. For more information: http://www.ru.nl/hfml/ 20 NanoLab Nijmegen NanoLab Nijmegen was begun as an initiative of the Institute for Molecules and Materials (IMM) at the Radboud University Nijmegen. It is managed by the research group Scanning Probe Microscopy in cooperation with five allied nano-research groups from the IMM. The goal of NanoLab Nijmegen is to make nano-technology and -science researchers and research apparatus available to small and medium business owners (SMEs). The arrival of nano-science and -technology has signaled the beginning of a new era where rapid developments are being made in previously unknown areas. There are already a large number of applications being developed for business application using nanotechnology. As well, improvements are also being made in existing processes and products. A few examples of sectors where these applications are most prevalent are electronics, medicine, energy, construction, sport, chemicals and cosmetics. For more than a decade, since 2002, NanoLab Nijmegen has used various means and methods to make the significant knowledge and experience of the nano-scientists in the region available for SMEs. Among their services are: Professional consulting Access to facilities: by either performing contract research or by allowing direct access to the labs, SMEs are able to take advantage of the modern facilities that make nano-production and application possible. Training: NanoLab Nijmegen also offers training in the apparatus that is necessary for converting materials to nano. Education and information services: NanoLab Nijmegen presents information at trade shows, and provides in-house presentations and laboratory tours for interested business wonders. For more information: www.ru.nl/nanolab 21 High Tech Factory High Tech Factory is the latest production location partnered with the MESA+ Institute for Nanotechnology at the University of Twente. MESA+ is where companies in Microsystems and nanotechnology can mass produce materials for the commercial market. An exceptional support system, where entrepreneurship for nanotechnology applications gets a serious boost. Companies are able to focus on their operations and invest their energy in growth, instead of struggling to arrange the sometimes messy details of running a business. High Tech Factory offers companies space, facilities and high-value cleanrooms. In addition, entrepreneurs have available to them the possibility to apply for funding: the High Tech Fund. This takes the form of an operational lease for available equipment should banks, private investors or seed funds not be ready to invest in the company. This allows the company to use production equipment necessary to ramp up production and to achieve production volume necessary for profit. What exactly the conditions are and how the fund operates can be found in the High Tech Fund fact sheet (in Dutch). Committed companies Companies that are committed to supporting the High Tech Factory are, among others: Blue4Green (Enschede), Bronkhorst (Ruurlo), Demcon (Oldenzaal), EnablingM3 (Dordrecht), Encapson (Nijmegen), IMS (Almelo), LioniX (Enschede), Medimate (Enschede), Medspray (Enschede), Micronit (Enschede), Nanomi (Oldenzaal), Ostendum R&D (Enschede), PhoeniX (Enschede), SmartTip (Enschede), SolMateS (Enschede), Twente Solid State Technology (Enschede), UNeedle (Enschede), UT International Ventures (Enschede) en Xio Photonics (Enschede). For more information: www.hightechfactory.com (in Dutch only) 22 Related Research Institutes Programs & Projects Top Program Overijssel: Support for Entrepreneurs Top Placement TOP stands for Temporary Entrepreneurs Placement (“Tijdelijk Ondernemers Plaats” in Dutch), an arrangement from the University of Twente and the Saxion University of Applied Sciences. For more than 25 years this arrangement has been helping innovative and entrepreneurial startups to make a running start. Participating companies have one-year access to a diverse range of support, consulting networking and financial help in order to have starting their company to be as successful as possible. For whom? TOP is intended for knowledge intensive entrepreneurs who generally are coming out of the sponsoring universities. TOP also encourages entrepreneurs who wish to cooperate with either, or both, of the institutes. The requirements of TOP are: The company is between 0 and 5 years old, inclusive The business concept is knowledge intensive or innovative The company has never before made use of the TOP position The company will be adding value to the economic activity in the region of East Netherlands Some sort of cooperation is planned with the University of Twente and/or the Saxion University of Applied Sciences. The support The participant in the TOP placement has access to a number of support possibilities. Assistance in working out a business plan, insofar as needed. In addition, every TOP company is eligible for a market scan (desk research) in order to determine the targeted market. There is also more specific support available: Financial support: an interest-free loan from the Rabobank Enschede-Haaksbergen and accounting support from Deloitte Coaching and advice in the area of communication and legal affairs from the Knowledge Park Twente Guidance from the universities in the area of technical expertise, as well as from a business coach. Office location Access to networks, such as the TKT (Technology Network Twente), the Entrepreneurs Club Business & Science Park, and the New Business Society of the football club FC Twente. The procedure Are you interested in a TOP placement? The first step is to make contact with Erwin Holtland (Coordinator Young Entrepreneurs) at +31 53 489 8989, or [email protected]. He will sit down with you to determine your eligibility. After this you will be evaluated by the TOP advisory commission. This commission meets on a monthly basis to examine new applicants, the progress of the program and the successful conclusion of participants in the TOP placement. More information www.kennispark.nl (in Dutch language) 23 NanonextNL NanoNextNL is a consortium of more than one hundred companies, universities, knowledge institutes and university medical centres, which is aimed at research into micro and nanotechnology. The total sum involved for NanoNextNL is 250 million euros, half of which is contributed by the collaboration of more than one hundred businesses, universities, knowledge institutes and university medical centres and the other half by the ministry of Economic affairs, Agriculture and Innovation. Micro and nanotechnology will make a significant contribution to resolving major societal questions such as keeping an ageing society healthy and keeping our environment liveable in a changing climate. The basis for being able to provide this contribution lies in the creation of an open, dynamic and sustainable ecosystem for research and innovation with which the Netherlands can continue to play its leading role in the world, and can extend this role further, in micro and nanotechnology. This ecosystem is created by initiating and guiding research projects within the themes. More information www.nanonextnl.nl VentureLab International & Soft Landing VentureLab International, formerly Venturelab Twente, provides business development for technologybased start-ups and is a business growth accelerator for well-established companies. VentureLab believes that the key to launching a company on the market as effectively as possible is not only the idea, but also all the entrepreneurial competences that form the basis of a successful business operation. It takes the steps to move from the business idea, to a business model, to running a fast growing, technology bases business. VentureLab helps businesses to build and grow- something which they cannot do on their own. Services VentureLab International offers a range of services for start-ups and growth seeking companies. Its business development program gives access to: Weekly training sessions on diverse subjects Experts on diverse subjects Fifty hours of coaching and progress monitoring Facilities such as meeting rooms, conference rooms or office space free of charge VentureLab International is open to entrepreneurs and business developers from the Netherlands and abroad. Foreign trainers and experts are in the programs and the official language is English. Free events VentureLab International also offers information meetings, open training sessions and lectures free of charge. They are held once a month by a renowned speaker from science or industry on a topic relevant to high-tech and high-ambition business development VentureLab Soft Landing Adding an international dimension is now within reach of many companies. It is becoming almost the same to do business overseas as it is at home, keeping a few things in mind, though. Other countries have other cultures and regulations. To cope with these differences choosing an entrepreneur-friendly 24 environment is crucial. VentureLab International is located in such an environment and can be your gateway to Europe. The home base of VentureLab is Enschede, the Netherlands. VentureLab International offers a full service pre-incubator programme for technology-based businesses. VentureLab gives access to the facilities and expertise of the University of Twente and Saxion University of Applied Sciences. Open innovation is embraced. A variety of networks is available. For business, sciences or services exclusively, as well as business & science & services platforms. There are mixed and dedicated incubators specialised in nano technology-related and ICT-related innovation and business development. The VentureLab partners and other support organisations have longstanding experience in business development support. In 2009, the National Business Incubation Association (www.nbia.org) awarded the NBIA Soft Landings International Incubator designation to VentureLab International. Through its Soft Landings programme, NBIA recognises incubators that are especially capable of helping nondomestic companies enter the incubator’s domestic market. VentureLab International joins a select group of programmes from around the world that have earned the designation since NBIA began the programme in 2005. VentureLab is the first of only two programmes designated in the Netherlands. The VentureLab International Soft Landings offer includes access to: Housing assistance (for business and staff) Help concerning immigration & visa, import/export laws, obtaining permits and licences Translation services Language training Cultural training Domestic market research and entry assistance Capital and potential funders Intellectual property protection / patent assistance For more information: www.venturelabinternational.com 25 UT International Ventures d/b/a MESA+ International Ventures Commercializing nanotech and life sciences MESA+ International Ventures (MIV) is a public-private incubator investment fund with a focus on + nanotechnology and life sciences. Together with research groups from the MESA research institute of nanotechnology of the University Twente, MIV is scouting and screening newly developed technologies for disruptive market potential. In case a technology screens favourable, a next step in the MIV commercialization process is embarked on: the market(s) for the technology is/are researched in precise detail, potential customers are contacted, the technology is developed towards a demonstrator (proto-type) product and the necessary Intellectual Property Rights (IPR) are secured. By so doing, a well-informed, thorough business plan for a spin-out company is prepared on which basis MIV can establish a new company to which it provides the necessary Series A finance. Subsequently, MIV will guide its portfolio companies towards a first licence deal within a codevelopment framework with one or more multinational partners, or it ensures that additional Series B capital is raised in the financial markets such that a MIV portfolio company can develop further and progress towards sustainable profits. Public-private finance and network MIV has obtained (share) capital from the University Twente. The financial contribution from the local province Overijssel is injected in a unique manner, namely as share surplus capital on the University Twente share in MIV’s holding company. This provides a special kind of Corporate Social Responsibility: not only will MIV’s portfolio companies provide new technologies for societal needs (e.g. improved health diagnosis, improved water purification and improved thermal insulation), the research institute that initiated and financed the bulk of the early technological developments will benefit significantly from dividends and/or exit money via its 60% (indirect) share of the actual share that MIV holds in a portfolio company. In this way, a revolving mechanism is offered to the university for future funding of research. The remaining finance stems from five private parties and management. All private investors also act as committed advisors and bring in a relevant network for future spin-out finance and with corporate leaders of multinational companies that could become off-takers of MIV technology that is commercialized. MIV Mission MIV Vision MIV Strategy Transform knowledge into economic good by exploiting and strengthening the MESA+ technology platforms Strong positioning at the forefront of the coming nanotech revolution, creating an entrepreneurial environment by bridging the gap between technology and markets Technology grants Scout /mine Screen Develop Public science Market Operations Analyse Screen Develop Capture Brand Distribute Define specs Quality and time Managem ent Qualified personnel Finance Investment in MIV Third party finance for spin-out ventures Subsidies Value creation 26 Programs & Projects Networks Kennispark Twente: an innovative place for knowledgeintensive companies Innovation and entrepreneurship are an integral part of the University of Twente in the east of the Netherlands. Ever since the 1980s the university has made both of these elements an essential part of institution policy, together with many partners. This has led to where innovation and entrepreneurship are an inescapable part of the environment, even outside the immediate location of the university itself. One of these places is Kennispark Twente (‘kennis’ is the Dutch word for knowledge. At Kennispark Twente there is everything one needs to be successful in entrepreneurship and innovation. Entrepreneurship New ideas and opportunities are being developed at the UT with a focus on high-tech with the human touch of the social sciences. The university has six research institutes. Teams of business developers follow the research output of the institutes and, using their knowledge of developments in the market and the economic potential of these ideas, work to bring them further into the market. This most often occurs in the form of spin-off companies and in joint research with industry. In addition, there are a number of education choices that also support entrepreneurship. These vary from short trainings to a minor in entrepreneurship. There is also a business development support structure for high-tech, high-ambition entrepreneurs, called Venture Lab International. Coaching and financial assistance is also available to assist startups. Innovation The University of Twente is open for cooperative relationships with the industry. This often occurs through facility sharing agreements, where companies are invited to use the research facilities and laboratories of the university. In addition, companies are encouraged to open innovation centers at Kennispark Twente. A good example of this is the ThermoPlastic Research Center (TPRC) in which the companies Stork, Ten Cate, Boeing and the university perform research into thermoplastic composites for the aircraft industry. Another example is the High Tech Factory, where approximately 20 companies together with the UT have established research and production facilities in the areas of micro- and nanotechnology. The long-standing clean room of the UT is being refurbished for this purpose. For small and medium enterprises Kennispark Twente has established so-called portals. Smaller companies can place research questions on these portals and will be linked to students, student entrepreneurs, spin-off companies and research groups of the university for the answer. In this way the knowledge of the university is made accessible for the business community. For more information on Kennispark: www.kennispark.nl 27 Technology Circle Twente (TKT) TKT (Technology Kring Twente; 'Kring' meaning Circle and Twente the hi-tech region in the Netherlands near the German border) is and active network of 180 high tech businesses in Twente aiming at co-operation and the exchange of information. Combining innovative potential TKT comprises about 200 high tech and expert businesses in Twente and was set up by the initiative of Twente University. It primarily targets the enhancement of economical opportunities for its members. Members TKT members are often young, high tech innovation and product developing companies; technical businesses employing between 10 and 25 staff. They aim at new developments and in their role of providers of knowledge form a link between Twente University and business life. As illustrated by the members’ list on the website, the members represent a wide range of technologies. Aims and activities TKT primarily aims at promoting her members’ interests by: Sharing knowledge, experience and expertise Advancing cooperation between members Creating members’ market profiles Supporting members’ business development Strengthening the position of the Twente region as a knowledge area TKT primarily tries to further project based cooperation. Joint product development Member firms have in the past worked together on a number of products and in doing so they have started to form small, semi-permanent conglomerates. Their flexibility and result driven culture has produced a string of innovative products and design awards. The TKT has played a major role in these projects, not as projectmanager but as an enabler. It is at TKT meetings that members meet informally and discuss projects, prospects, possibilities and problems. Through their long acquaintance members have come to know and trust others. This trust is crucial in building commercial relationships in product development because so much remains unsure, even after the most thorough plan has been hatched. Bright future The long history of close cooperation with the University Twente, the informal network and product development initiatives have culminated in the Knowledge Industry initiative. This should be a strong basis for future growth. As a technical magazine recently noted, the TKT is the “High Tech palette of Twente” For more information visit: www.tkt.org 28 MinacNed The Microsystems and nanotechnology cluster, shortly MinacNed, is an association aiming to strengthen the Dutch economic activity based on microsystems and nanotechnology in the Netherlands. Members are research institutes, equipment manufacturers, suppliers and users of technological components. The entire supply chain is represented by this association. MinacNed has about sixty members. The board of the association consists of eight persons and represents also the scientific research programs MicroNed and NanoNed. Chairman is Ronny van 't Oever, technical director of Micronit Microfluidics Enschede. About three times a year, MinacNed organizes member meetings, with a (prospective) member hosting the meeting. During these meetings, association business and activities are discussed. Each meeting will be dominated by lectures about a current topic. In addition, the meetings are an excellent opportunity to network. New members and members with a new development are given the opportunity to present themselves or their innovations by an elevator pitch. For more information: www.minacned.nl 29 Locations Kennispark Innovation Campus Kennispark Twente is also a business park/innovation campus for knowledge intensive entrepreneurs. The Kennispark organization controls the physical development of the regional innovation infrastructure centered around the University Campus, the Hengelosestraat and the Business & Science Park Enschede. These area’s blend together into one Innovation Campus. Kennispark Innovation Campus has been recognized as one of the campuses of national importance. Kennispark offers facilities dedicated to knowledge intensive entrepreneurs such as office space and laboratories. Amongst others: Business & Science Park Enschede A melting pot of innovative activities where "science" as well as "business" profit from each other, technologically as well as commercially. The successful BSP formula can be seen as resulting from a unique location, outstanding facilities, an intensive and active knowledge exchange, and an atmosphere that encourages mutual beneficial cooperation. Value added business location, offices and business services centers Outstanding infrastructure, public transportation connections (including exclusive train station) Park-like setting with planned green areas, water sculpture and art objects Home of the championship FC Twente soccer team, the Arke Stadium, is adjacent the park, which also houses business centers and has as an amenity a 2000 car capacity parking lot. BTC Twente Incubator for companies who want to start small and want to have flexibility with their lease contract. BTC has several options for offices and specific facilities (labs, warehousing) in several buildings. High Tech Factory Shared production facilities for micro- and nanotechnology related companies at the University Campus. The Corridor Building for innovative entrepreneurs with office space and several possibilities for large and small conferences. The Gallery In the framework of creating an inspiring business environment for knowledge intensive companies, the university and other private parties are redeveloping the university’s longest building into a unique and multifunctional business center: The Gallery. The building is located on the edge of the university campus, across from the adjacent industrial estates, and will become the centerpiece of the Kennispark Twente knowledge center. It is the first -and most high-profile - of the buildings in the area to be dealt with as part of the redevelopment efforts of the area around the university. The Gallery building will provide 55,000 m2 of space 30 (nearly eight football fields) for laboratories, offices, manufacturing areas and exhibition halls. The building’s unique location enables it to bridge the gap between science and industry. The building, with its unique architecture and convenient location, will be transformed into a 300meter-long ‘showcase’ where scientists and businesses can raise the profile of their new developments. The building will be housing an incubator for start-ups in nano-, biomedical technology and the IT sector. The Gallery is also available to R&D departments of large companies, high-end laboratories and production facilities. For more information on Kennispark: www.kennispark.nl For more information on Business & Science Park: www.sciencepark.nl and www.ovbsp.nl 31 Mercator Technology & Science Park Mercator Technology & Science Park started as a public private initiative in the nineties. Its primary aim was to create a meeting place for scientists and companies. Mercator offers more than only office space, it also offers links to the research fields of Radboud University Nijmegen, such as cognition sciences, IC technology, bio-informatics, bio-medical research, molecular life sciences and material research. Mercator offers unique possibilities for a cross-fertilization between science & business. The University Medical Centre St. Radboud is in walking distance and there is access to strong research centers for language and speaking technology and neuroscience. It is also possible to use nearby laboratories and research facilities such as the Nanolab and Innovationlab and to cooperate with research institutes and science-based spin off companies. Mercator is a dynamic centre where university talent and innovative entrepreneurs are attracted to and interaction leads to new products and services. Short lease possibilities; “easy in – easy out” Office space from 25 sqm up to several floors. High-tech conference rooms. For more information: www.mercatorsciencepark.nl (only in Dutch) 32 Nanotechnology Companies in East Netherlands 33 3T 3T BV is a leading independent solution provider in the market for customer-specific industrial products and systems, based on microelectronics and software.3T's all-round team is specialized in engineering solutions for complex applications. They use state-of-the-art microelectronics, embedded software and systems, PC software, sensors and microsystem technology to translate your concept into a tailor-made solution. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production 20-49 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.3t.nl Aquamarijn Micro Filtration Aquamarijn creates new technologies for filtration, (micro) analysis, cell detection, nanopatterning and micro moulding using nano and micro engineering. Aquamarijn is specialized in MEMS micromachining, polymeric micro moulding and fiber spinning techniques.Nano and Micro Engineering- Aquamarijn introduces the microsieve a micro filtration membrane- Smart, portable and inexpensive sensor templates Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Zutphen R&D 2-4 (Provincie Gelderland, PWE) Netherlands For more information: http://www.aquamarijn.nl 34 AeroTech Development AeroTech Development is an in January 2010 founded high-tech University of Twente spin-off company, which specializes in the development and valorization of nanocomposite polymers with a tunable porosity and pore sizes at the micrometer and nanometer lengthscale through utilization of state of the art polymer engineering and nano-technology. The developed porous nanocomposite materials have a great potential for utilization in a wide varity of applications encountered in every day life. In addition, AeroTech Development offers their expertise in 2D/3D surface modification reactions, surface characterization and thermal analysis of polymers to customers with specific needs in those areas. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Heteren development & valorization 1 (Oost NV) Netherlands For more information: http://www.atdnano.com/ Blue4Green Blue4Green is a young, innovative company developing technology for better and faster methods to diagnose ailments and diseases in animals. Blue4Green's technology enables veterinary professionals to diagnose on the spot, allowing for precautionary measures and faster treatment of sick animals. The Lab-on-a-Chip technology was developed in an international effort spanning many years. In 2000, the Lab-on-a-chip Group at Twente University and the MESA+ Institute for nanotechnology started a collaborative study into new methods to measure lithium levels in blood samples. The study was successful and showed that levels of other charged particles, such as calcium and magnesium, can be measured as well. More research is required to prepare the Lab-on-Chip technology for production aimed at other applications. Blue4Green therefore engages in intensive research efforts with scientific partners around the globe. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D 2-4 (Oost NV) Netherlands For more information: http://www.blue4green.com 35 Bronkhorst High-Tech Bronkhorst High-Tech B.V., established in 1981, offers the most extensive product range of thermal mass flow meters and controllers on the market. Numerous styles of both standard and bespoke instruments can be offered for applications in laboratory, industrial and hazardous areas.The full scale measuring range (with 50:1 turndown) for these instruments can be selected between 0-1 mln/min and 0-10000 m3n/h for gases and 0-30 mg/h up to 0-20 kg/h for liquids. Furthermore Bronkhorst High-Tech offers pressure transducers and controllers with a minimum range of 0-100 mbar and a maximum range of 0-400 bar. Bronkhorst's Coriolis Mass Flow Meters/Controllers for gases and liquids have a measurement capability between 0,4...20 g/h and 6...600 kg/h. The most recent development is a series of ultra-compact, chip-sensor based Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Ruurlo R&D, Production, M&S 200-499 (Oost NV) Netherlands For more information: http://www.bronkhorst.com Cameron Health Cameron has developed a totally subcutaneous implantable defibrillator (S-ICD) System that remedies many of the issues associated with traditional implantable cardioverter defibrillators (ICD’s). Specifically, Cameron's S-ICD System is designed to be smarter, more capable, and less time-consuming to implant, program and follow-up. An ICD is a small battery powered electrical pulse generator that is implanted in patients who are at risk for ventricular tachyarrhythmias. Cameron’s concept: Effortless Rhythm Management. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Health Arnhem Sales, distribution, wholesale 1 (Provincie Gelderland, PWE) United States For more information: http://www.cameronhealth.com 36 Dannalab DANNALAB is an independent company offering a range of analytical services for characterization of pharmaceuticals, polymers and other materials. Some of Dannalab's services are related to intellectual property and patents. Dannalab's business is based on novel characterization techniques combined with an expertise in dedicated instrumentation. As well as the analytical services that the company provides, it is involved in contract research targeting new analytical methods; in both hardware and software. These projects are being conducted for one of the major suppliers of analytical X-Ray instrumentation - PANalytical B.V. (formerly Philips Analytical) - and results are implemented in the commercial products.Dannalab's research partners include: - PANalytical B.V. - MESA+ Institute of Nanotechnology Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D (Oost NV) Netherlands For more information: http://www.dannalab.com Delta Mask Delta Mask was founded in 1984 and has a wide experience in mask making. The company started with producing photoemulsion masks, but nowadays only 4x4 and 5x5 inch chromium masks are produced. Delta Mask cooperates closely with WIEWEB a company that develops software for designing Sensor and IC- layouts. Data formats which can be handled for mask making are the CIF, GDSII and DXF.Delta Mask uses chrome blanks, fabricated by Hoya, for mask making. Glass quality of the plates is Soda Lime, to keep the price of a mask as low as possible. Thickness of the chrome layer is 980 Å Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Fabrication, Sales 2-4 (Oost NV) Netherlands For more information: http://www.deltamask.nl 37 Demcon Demcon realizes high-tech mechatronic systems and products through research, development and production. Demcon generates high-end solutions for complex issues in various markets, ranging from semicon and defense to medical and life sciences. Demcon offers complete mechatronic solutions: mechanics, electronics, software, optics/lasers, mechatronic system engineering, industrial design, prototyping and production. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 20-49 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.demcon.nl eMALDI eMALDI is a novel patented technology that transforms the popular analytical detection method MALDI-MS into a more sensitive, robust and faster method by solving a bottleneck in sample preparation stage. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 1 (Oost NV) Netherlands For more information: http://www.emaldi.eu 38 Encapson Encapson is a dynamic, technology-driven company that specialises in the use of polymer-based capsules for microencapsulation. Encapson can encapsulate a wide range of compounds, such as enzymes, pharmaceuticals, catalysts and oils. The use of different building blocks allows Encapson to prepare microcapsules with a variety of properties, such as biodegradability, porosity, size and stability. Next to continuously performing contract product development R&D, Encapson develops new products using micro-encapsulation technology. Encapson developed two products Capsol and Sonocoat. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Nijmegen R&D 5-9 (Provincie Gelderland, PWE) Netherlands For more information: http://www.encapson.com IBIS Technologies IBIS Technologies is an analysis and instrumentation company for label free and in depth monitoring of multiple biomolecular interactions using array technology. IBIS Technologies is developer and supplier of biosensor based analytical instrumentation and consumables for the Life Science and R&D markets. Focus is to provide users with high end instrumentation of uncompromised quality in combination with lowest costs of ownership. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Hengelo (O) R&D, production, sales Netherlands For more information: http://www.ibis-spr.nl 39 IMS IMS delivers worldwide manufacturing solutions to customers in the high precision, electronics and medical industry. IMS is an experienced company in the field of manufacturing solutions for micro assembly challenges. IMS provides micro assembly solutions to customers worldwide for more 10 years now. As part of the WWINN group IMS has access to a broad network of partners. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin For more information: http://www.ims-nl.com Technology Almelo Development, assembly, installation 20-49 (Provincie Overijssel, BIRO) Netherlands Inertia Using low-cost wireless sensor nodes, Inertia captures and monitors the motion of people and moving objects, recognizes current situations and activities, provides constructive feedback and takes appropriate actions. The Inertia system is a collection of intelligent sensor nodes that build a wireless network. Using the wireless medium as the communication channel, the system processes data collaboratively and performs distributed monitoring and actuating tasks. Unique to the Inertia system is that it can analyze the dynamics of the environment using only lowpower wireless sensor nodes. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, M&S 2-4 (Oost NV) Netherlands For more information: http://www.inertia-technology.com 40 LioniX LioniX is a leading provider in development and small to high volume production of leveraging and innovative products based on microsystem technology and MEMS. Core technologies are integrated optics and microfluidics. LioniX also provides MEMS foundry services. The combination of microfluidics and integrated optics gives LioniX an unrivalled expertise in the emerging area of Labon-a-Chip, while the combination of integrated optics with the micromechanics expertise assures us a strong position in the area of MOEMS (Micro-Electro-Optical Mechanical Systems). Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales Unknown Netherlands For more information: http://www.lionixbv.nl MASER Engineering MASER Engineering, founded in 1993, is an independent engineering service company operating in the semiconductor and electronic systems industry. Reliability Test and Diagnostic services are offered to a wide range of customers that are active as Fabless Semiconductor or Integrated Device Manufacturers, automotive electronics supplier or in Aerospace and Space applications. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Testing, Consulting, Engineering 20-49 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.maser.nl 41 Medimate Medimate develops healthcare solutions for healthcare professionals, patients, and researchers by using a unique, manageable measuring instrument, the Medimate Multireader®. With this Multireader® and a Disposable Chip, Medimate offers solutions for situations in which a high added value is created by taking decentralized measurements or self monitoring the concentrations in the blood level. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Health Enschede R&D, production, sales 5-9 (Oost NV) Netherlands For more information: http://www.medimate.nl Medspray Medspray develops and produces unique spray nozzles for near mono-disperse aerosol devices. All devices and spray nozzle units are based on own proprietary technology. Inhalation therapy becomes more effective and simple. Medspray develops the device and the manufacturing technology for the next generation mono-disperse liquid based aerosol and spray devices. The devices generate aerosols with pre-set (customized) particle size distributions. Technology is centered on design and manufacturing of small atomizers using lithography based, wafer scale, micro machined nozzle membranes. Focus is on simple but very efficient local or systemic delivery of drugs, targeted to specific sites in the human body. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 5-9 (Oost NV) Netherlands For more information: http://www.medspray.nl 42 MicroCreate MicroCreate is an independent company providing MEMS foundry services, consultancy and fabrication of microdevices for corporate and academic research laboratories who want to outsource cleanroom processing and might not have access to critical equipment and technologies as provided by the Mesa+ NanoLab at the University of Twente. The company was founded in 2012 by ir. Kechun(Kees) Ma, working as cleanroom freelancer (ZZPer), having more than 10 years experience in MEMS fabrication at the Transducers Science and Technology (TST) research group at the University of Twente, The Netherlands. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Consultancy, Fabrication 1 (Oost NV) Netherlands For more information: http://www.microcreate.nl Microflown Technologies Microflown Technologies develops and markets highly innovative products and (on site) testing services in the field of noise and vibration. Microflown Technologies develops and markets innovative (acoustic) testing techniques to the aerospace, automotive and defence industry. Within the vehicle manufacturing industry, Microflown based testing methods are used for both the development of new prototypes and end of line acoustic testing during manufacturing Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Arnhem R&D, Production, M&S 10-19 (Provincie Gelderland, PWE) Netherlands For more information: http://www.microflown.com 43 MicroNext MicroNext is specialized in the development of technology for the production of micro and nano texturized polymeric products. Polymeric micro molding is applied for large-volume production of micro structured flat sheets and fibers for e.g. textile and polymeric filters. MicroNext offers proactive support in research and development for successful implementation of polymeric micro molding solutions. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Zutphen R&D, production, sales 1 (Oost NV) Netherlands For more information: http://www.micronext.nl Micronit Micronit has been manufacturing glass-based lab-on-a-chip products for more than ten years. Micronit has extensive experience in micromachining and microfluidics and is a key supplier of microfluidic devices to life sciences and chemistry markets. Micronit is providing high quality lab-ona-chip components for analytical instrumentation and is also a dedicated research and development partner for both science and industry. Microfluidic glass chips are manufactured by etching or powderblasting holes, cavities, microchannels and nanochannels in glass substrates. If required electrodes can be integrated in the devices. These substrates are then bonded and diced to create the individual devices. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, development, production, sales 20-49 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.micronit.com 44 Mosaic Systems Mosaic Systems BV is a Dutch biotech-focussed company specializing in large scale biologics separation and purification for Agri, Food Ingredients, and (Bio)Pharmaceuticals. Limiting factor currently is through-put resulting in limited productivity [kg/hr]. Mosaic Systems has solved the through-put limitations providing a 4 to more than 50 times higher productivity. Mosaic Systems develops Mosaic Systems Module™ concepts to perform under a wide variety of process conditions, based on your current chromatography medium, for high productivity, high resolution and low buffer consumption. Through a patented mixed-matrix-membrane process Mosaic Systems manufactures for a variety of process conditions: pre-filtered feeds, direct adsorption from fermentation broth, combining filtration and chromatography. Proof-of-Technology has been shown with several (multinational) customers in Food Ingredients, (Bio)Pharma and Dairy. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Health Enschede R&D, production, service, sale 2-4 (Oost NV) Netherlands For more information: http://www.mosaicsystems.nl MyLife Technologies MyLife Technologies develops and fabricates ceramic micro needle arrays. The micro needles can also be coated with a substance that needs to be delivered so it will dissolve into the skin. It is also possible to make the needles electrically conductive and use them as electrodes for EEG measurements. MyLife Technologies continuously expands its knowledge on micro and nanofluidic transport both in the patch and in the micro needles. MyLife Technologies can also supply research groups with micro needle arrays or do contract research. MyLife Technologies' micro needle arrays provide a practical and easy method for sampling and administering of substances relevant to the user. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D Netherlands For more information: http://www.mylifetechnologies.nl 45 Nanomi Nanomi is a drug delivery company providing expertise and technology for the development and manufacture of microsphere based injectable controlled release formulations. The company's proprietary Monosphere Technology, that brings the precision of semiconductor technology to the pharmaceutical field, provides unprecedented predictability, uniformity and scalability of the microsphere manufacturing process from lab to fab. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Health Oldenzaal R&D 1 (Oost NV) Netherlands For more information: http://www.nanomi.com NanoPhysics NanoPhysics B.V. is an independent analytical service lab providing integral analysis solutions for many industries like semiconductor, automotive, pharmaceutical, renewable energy and nanotechnology. They also serve research institutes, suppliers, universities and high tech companies. The company was founded in 2011 by ir. Patrick Grunder and ing. Tim Velthof. They both studied Applied Physics and have more than 15 year experience in the semiconductor industry. They both encourage collaborative projects with both private and public research sectors. Due to their solid network of complimentary partners and personal knowledge and care they are capable to offer their customers an integral solution for complex cases and connect the right dots. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 2-4 (Oost NV) Netherlands For more information: http://www.nanophysics.nl 46 Nanosens Nanosens develops and utilizes the latest developments and advancements of the just emerging and exciting nanotechnology to make smart, portable and inexpensive sensing systems for ultrasensitive and rapid detection of biological and chemical species. Nanosens works to bring innovative ideas and concepts from the sensor laboratories to the application worlds (I2A). With focus on the sensor application areas that have a great impact on society and on industry, such as: Nanobio and chemical sensors for life sciences and health care (medical), security (warfare), and water control Nano gas sensors for the automotive, pollution control, safety and health. Besides active R&D on nanosensor technology, Nanosens also will offer " Micro and Nano Technology Foundry Services" (MEMS/NEMS) to customers. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Health Zutphen R&D Netherlands For more information: http://www.nanosens.nl NXP NXP Semiconductors N.V. (Nasdaq: NXPI) provides High Performance Mixed Signal and Standard Product solutions that leverage its leading RF, Analog, Power Management, Interface, Security and Digital Processing expertise. These innovations are used in a wide range of automotive, identification, wireless infrastructure, lighting, industrial, mobile, consumer and computing applications. A global semiconductor company with operations in more than 30 countries. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Nijmegen R&D, Manufacturing, M&S >1000 (Provincie Gelderland, PWE) United States For more information: http://www.nxp.com 47 Nymus 3D Due to the broad skillset available in-house, animations can be delivered at a high technical and visual level. Scientific visualisation: animation, illustration and cover images Architectural visualisation: from single buildings to big areas Interactive Web Applications Stereo3D presentations and setups Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Design, Consultancy, Sales 2-4 (Oost NV) Netherlands For more information: http://www.nymus3d.nl Optisense Optisense develops highly sensitive biosensors for real-time monitoring of contaminants and biochemical substances. The Optisense ‘Lab-on-Chip’ sensor is used for real-time and on-site detection. Based on a unique combination of an integrated optic chip, a biochemical transduction layer, micro-fluidics and electronics, the Optisense patented ‘Lab-on-Chip’ sensor technology guarantees high-end laboratory sensitivity (lower parts per billion range). Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Research & Development 5-9 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.optisense.nl 48 Ostendum Ostendum is a group of companies that focuses on the commercialization of optical detection methods regarding the presence of micro-organisms, biomarkers, (bio-) molecules and (nano-) particles. Ostendum develops and produces both the necessary hardware and software, including its own lab-on-a-chip line. Ostendum’s technology platform classifies as nanotech as well as biotech and Ostendum claims that its detection limit is at least 100 times more sensitive than currently available competing detection methods. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D Netherlands For more information: http://www.ostendum.com PANalytical PANalytical is the world's leading supplier of analytical instrumentation and software for X-ray diffraction (XRD) and X-ray fluorescence spectrometry (XRF), with more than half a century of experience. The materials characterization equipment is used for scientific research and development, for industrial process control applications and for semiconductor metrology. The product portfolio includes a broad range of XRD and XRF systems and software widely used for the analysis and materials characterization of products such as cement, metals and steel, nanomaterials, plastics, polymers and petrochemicals, industrial minerals, glass, catalysts, semiconductors, thin films and advanced materials, pharmaceutical solids, recycled materials and environmental samples. PANalytical is part of Spectris plc, the precision instrumentation and controls company. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Almelo R&D, production, sales 200-499 (Provincie Overijssel, BIRO) United Kingdom For more information: http://www.panalytical.com 49 Pentair X-Flow (former Norit X-Flow) Water...life depends on it. And although about 70 percent of the earth's surface is covered with water, more than two billion people are deprived of a constant and reliable source of drinking water on a daily basis. Worldwide, governments, municipalities and industries face the challenge of safeguarding current and future drinking and process water requirements. These dire circumstances cannot be tackled simply by doing more of the same; they require new visions and cutting-edge innovations.This is why Pentair X-Flow, the world's leading ultrafiltration (UF) technology company for both small and large scale systems, is constantly investing in research and development to increase the performance and efficiency of a proven technology and pioneering new solutions for water purification.One of Pentair X-Flow's answers to the world's water crisis is the advanced engineering upgrade to the Norit AquaflexTM UF system. With a proven membrane technology at its core, the Norit AquaflexTM is the best performing water treatment system at a considerably lower total cost of ownership. Addressing the emerging legislation for turbidity and microbiology, the Norit AquaflexTM system provides superior separation performance and effectively rejectsviruses and chlorine resistant organisms, such as Cryptosporidium and Giardia. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede production, sales, research and development 50-99 (Provincie Overijssel, BIRO) United States For more information: http://www.x-flow.com/ PhoeniX software PhoeniX enables companies and institutes worldwide with software solutions to design and manufacture. PhoeniX is currently serving more than 150 customers worldwide, from SME's to large multinationals, from private persons to major research institutes. Their activities are in many different fields of the micro and nanotechnology landscape, like: - micro fluidics - BIO sensors - compound semiconductors - MEMS & MOEMS - integrated optics & photonics - RF micro electronics - nano materials research Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales, service Netherlands For more information: http://www.phoenixbv.com 50 Relitech ReliTech, a merger of "ReliableTechnology", is a reliable partner (co-creator) for the development of practical solutions in measurement techniques. One of the products developed by ReliTech for Viasys Healthcare is the Oxycon Mobile, a portable ergo-spirometry product. The system consists of: SBx: Sensor Box (Measurement unit for volume and breathing gasses) DEx: Data Exchange Unit (Data storage and communication module) PCa: Powersupply en Calibration Unit Host: PC to control the test and for on-line presentation of the measurement data Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Almelo R&D, sales, service 10-19 (Provincie Gelderland, PWE) Netherlands For more information: http://www.relitech.nl Satrax SATRAX is working to introduce revolutionary antenna system which will provide users in ground transportation, nautical, and avionics industries with high-speed flexible satellite broadband communication. SATRAX develops system that meets future requirements for broadband communications with an ultra flat "smart" antenna, capable of maintaining connection with satellites even at high speeds.Smart Antenna Satcom Systems Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D 1 (Oost NV) Netherlands For more information: http://www.satrax.nl 51 Sensata Technologies Holland Sensata Technologies provides leaders in the global automotive, appliance, aircraft, industrial, and HVAC markets with sensing and protection solutions. Sensata's European business and technology development center is located in the Netherlands. Sensata Technologies Holland B.V. offers a wide range of products including sensor, control, and protection products. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Almelo R&D, production 200-499 (Provincie Overijssel, BIRO) United States For more information: http://www.sensata.nl Sentron Europe Sentron is a high tech company that designs and produces high quality pH sensors and pressure sensors: ISFET pH sensors are very robust and small in size. This differentiates them from conventional glass electrodes and other ISFET sensors which are fragile and / or larger in size. Sentron’s ISFET pH sensors are the only ISFET pH sensors used in FDA approved medical devices Pressure sensors are small yet highly accurate and are incorporated into a wide range of medical devices Sentron also provides design support and sub assembly services to OEM customers that integrate these sensors into their products. In addition, Sentron offers its own line of high quality pH meters and ISFET probes suitable for applications requiring robust glass-free and / or small pH measurement. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Roden Design, Production, Sales 10-19 (Oost NV) Netherlands For more information: http://www.sentron.nl 52 SenzAir SenzAir focuses on the diagnostics of exhaled air. The SenzAir technology enables the measurement or monitoring of the physical health of people in a patient-friendly and non-invasive way in an early stage. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Research & Development Netherlands For more information: http://www.senzair.nl SmartTip SmartTip specializes in the design, production and packaging of dedicated special purpose SPM probes. SmartTip provides corporate and academic research laboratories with "Smart" probes for any SPM application requiring more than just a bare Silicon or Nitride probe. SmartTip has developed its Smart Coating technologies for MFM probes. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Design, production and packaging Unknown Netherlands For more information: http://www.smarttip.nl 53 SolMateS SolMateS is a high-tech company, offering material science related services. They pioneered and developed in 2007 a new coating process called Large Area Pulsed Laser Deposition and coat since 2008 polymer optics for the military market. SolMateS-Piezo is the latest using the novel process to deposit PbZrTiOx (PZT) thin films. Customers are using the Piezoelectric thin films as their basic building block for several MEMS applications such as: print-heads, micro-pumps, energy harvesters, tilt-table mirrors, IR-sensors, high K capacitors and ultrasound transducers. With this production solution thin films of PbZrTiOx (PZT) are currently produced and compatible with standard silicon process technology. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, Production 10-19 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.solmates.nl Tide Microfluidics Tide Microfluidics' novel platform technology allows for the creation of monodisperse microbubbles. The platform shows a robust production method for microbubbles of highly controlled size with a narrow size distribution. This unique platform enables the formation of monodisperse microbubbles with size choice between 2 to 10 microns and a narrow size distribution. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 2-4 (Oost NV) Netherlands For more information: http://www.tidemicrofluidics.nl/ 54 Thales Nederland Thales Nederland is the largest defence company in the Netherlands and world-famous for its naval radars and electro-optic sensors and naval combat system. Thales Nederland is active in projects that are pursued by foreign Thales entities for Dutch customers. In this manner, Thales has supplied KLM (Royal Dutch Airlines) with simulators. Thales is also actively involved in the national introduction of electronic payment systems for public transport. The so-called Smart Card will in time be the sole ticket used in Dutch public transport. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Hengelo (O) R&D, Production, Logistic Services 10-19 (Provincie Overijssel, BIRO) France For more information: http://www.thalesgroup.com Twente Solid State Technology (TSST) Twente Solid State Technology (TSST) is specialized in design and production of customized thin film deposition equipment, specifically Pulsed Laser Deposition equipment for advanced studies. An example is the use of Reflection High Energy Electron Diffraction (RHEED) under high-pressure conditions, which gives real-time information about the surface morphology during depositions. The company also produces ceramic thin films, and offers services for research in the field of ceramic thin films, such as the surface treatment of ceramic substrates. TSST is able to provide these services due to the strong cooperation with the MESA+ institute at the University of Twente. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede Design & Production Netherlands For more information: http://www.tsst.nl 55 U-Needle Silicon micro needles U-Needle develops and produces micro needles employing its patented in-plane silicon etching method. These micro needles cause minimal stress and pain when vaccinating or administering drugs to patients. Atom Sharp U-Needles are atom sharp and have a relatively short bevel to facilitate shallow injections with high precision. U-Needles are made of mono crystal high grade silicon, which is biocompatible and shows no leachables. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales 2-4 (Oost NV) Netherlands For more information: http://www.uneedle.com VDL Enabling Technologies Group VDL Enabling Technologies Group is a tier-one contract manufacturing partner, delivering high tech capital equipment to leading OEM companies and users of advanced production lines. Services include prototyping, customer specific factory automation projects and series manufacturing of 'highmix low-volume' products. VDL operates from 6 manufacturing locations in Europe and Asia. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Almelo R&D, production 200-499 (Provincie Overijssel, BIRO) Netherlands For more information: http://www.vdletg.com 56 WieWeb Software WieWeb software is a small software company specialized in the development of technical, scientific and mathematical software. Main product is the layout editor CleWin, a layout editor designed in cooperation with MESA+ at the University of Twente and Deltamaks, a mask making company. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Hengelo Software design Netherlands For more information: http://www.wieweb.com XiO Photonics XiO Photonics exploits a photonics integration platform from the UV to IR that offers integrated optical solutions for products ranging from telecom, datacom & sensing and visible light applications. XiO Photonics supplies besides standard fiber optical products, like splitters and patchcords, also the next generation optical modules that integrate advanced functionality on a compact optical chip. This way the benefits of integration, known from the IC industry, can be used for photonic applications. Sector Location in (East) Netherlands Activities in East Netherlands Company size range Country of origin Technology Enschede R&D, production, sales Netherlands For more information: http://www.xiophotonics.com 57 Part 2: General Information East Netherlands 58 East Netherlands East Netherlands is located strategically between two key European economies: the Dutch Randstad (Amsterdam, Rotterdam, Utrecht) and the German Ruhr Area (i.e. Düsseldorf, Cologne). Schiphol Amsterdam Airport is within 60 - 90 minutes travel by car or (direct) train Like the rest of the country, East Netherlands has a highly educated, multilingual and internationally oriented workforce. East Netherlands is a focal point for medical life sciences and medical devices. There are strong science and business clusters around university and medical centre in Nijmegen and Technical University Twente in Enschede. Some Figures Population Labor Force 2012 Land Surface 2008 GDP per head 2010 Top 3 Universities 3,148,413 (per 1-1-2012) 1,439,000 855,737 ha Gelderland € 29.899 Overijssel € 31.389 Wageningen Universiteit: Agrifood Universiteit Twente: Hightech Materials Radboud Universiteit Nijmegen: Life Sciences & Health source CBS Stattline 59 East Netherlands in Figures Population (1-1-2013) Land surface (km2) (2012) Population density per km2 Labor force (age 15-65), 2012 x1,000 - primary education x1,000 - secondary education x1,000 - higher education x1,000 GDP (* million €), 2010 GDP per head (* 1,000 €), 2010 Number of jobs, December 2011 x1,000 Unemployment (%, 2012) Netherlands East Netherlands Gelderland Overijssel 16,779,575 33,718,28 496 10,992 3,344 4,432 3,108 300,434 35,616 3,155,141 8,294,01 374 2,038 631 856 533 26,023 30,644 2,015,791 4,969,52 405 1,304 408 536 348 33,104 29,899 1,139,350 3,324,49 342 734 223 320 185 18,942 31,389 7,904,6 6,4 1,446,2 6,5 914,3 5,7 531,9 6,4 Source: CBS/Statline, July 2013 Southwest Gelderland Arnhem/ Nijmegen 236,688 696,06 339 716,391 898,85 794 400,727 1,545,90 260 661,985 1,828,71 360 626,726 1,489,47 421 1525,818 416,38 367 3659,806 1,418,68 252 154 56 64 33 3,545 29,841 476 131 183 157 12,040 30,297 254 81 115 55 5,947 26,519 421 140 174 103 11,571 31,570 404 125 176 99 10,131 30,658 100 26 43 30 2,423 28,581 230 72 101 56 6,388 33,890 102,1 4,8 329,1 7 165,9 5 317,3 4,9 282,7 6,9 69,8 5,7 179,4 5,8 Population (1-1-2013) Land surface (km2) (2012) Population density per km2 Labor force (age 15-65), 2012, x 1,000 - primary education x1,000 - secondary education x1,000 - higher education x1,000 GDP (* million €), 2010 GDP per head (* 1,000 €), 2010 Number of jobs, December 2011 x1,000 Unemployment (%, 2012) Achterhoek Veluwe Twente Southwest Overijssel Source: CBS/Statline, July 2013 Major cities in East Netherlands Apeldoorn Arnhem Ede Enschede Nijmegen Zwolle Population (2013) 157,315 149,827 109,823 158,627 166,382 122,562 Source: CBS/Statline, July 2013 60 North Overijssel Infrastructure in East Netherlands The infrastructure in East Netherlands is well developed and offers excellent, direct access to national and international road networks. Traffic density is relatively light and the region is well served by international, national and local rail systems. East Netherlands is one of the strategic hubs of Europe, centrally situated between important economic centers such as the Randstad conurbations in the west of the Netherlands and the Ruhrarea in Germany. It is only a short distance from Amsterdam Airport (Schiphol), Port of Rotterdam, Airport Münster-Osnabrück (FMO), Düsseldorf International and Airport Weeze. The arrival of the Betuwe Route (freight rail) and the High Speed Line rail links in the east of the country ensures even more efficient transportation. Overland Highway A1 A2 A12 A15 A28 A30 A32 A35 A50 A73 From Amsterdam Amsterdam/Utrecht The Hague Rotterdam Utrecht A1 North-Netherlands Almelo Zwolle Nijmegen Miles Amsterdam Antwerp Berlin Dusseldorf Hamburg Copenhagen London Madrid Milan Munich Paris Prague Rotterdam The Hague Warsaw 65 100 370 75 250 445 335 1,100 610 450 320 525 75 75 720 Via Apeldoorn/Hengelo Ede/Arnhem Zwolle Zwolle Hengelo/Enschede Apeldoorn MILEAGE CHART Arnhem KM Travelling Time by Car 105 1h10 165 1h40 595 5h35 120 1h10 400 3h45 720 7h25 540 6h 1,775 16h45 980 9h15 725 6h40 515 4h50 850 7h35 120 1h15 120 1h15 1,160 12h35 To Germany South-Netherlands, Belgium Germany Arnhem/Nijmegen North-Netherlands Ede Middle-Netherlands Germany Arnhem South-Netherlands/Germany Miles Enschede KM 100 160 315 85 195 400 400 1,160 615 460 375 450 125 125 665 160 260 510 135 315 640 640 1,870 990 740 610 730 200 200 1,075 Travelling Time by Car 1h40 2h30 4h55 1h20 3h 6h45 6h55 17h30 9h25 6h45 5h45 7h05 1h60 1h60 11h55 Source: Google Maps 61 Railroads National lines From every large city in East Netherlands one can travel westwards directly to Amsterdam, Utrecht and Rotterdam on efficient “InterCity” rail lines. These trains connect more than 30 cities in the Netherlands. For longer distances InterCity lines are ideal because of their speed and comfort. The trains appear in the vast majority of stations along designated routes every 30 minutes. In addition to the InterCity trains there are many “stop-trains” which cater to the smaller stations along the routes. International lines Several international lines cross East Netherlands. From the cities Arnhem and Nijmegen international railroads crosses the border with Germany. This means direct connections to the Ruhr-area and further to southern and eastern Europe. In addition a major west-east international line comes from the western parts of the Netherlands and runs via the cities of Apeldoorn, Almelo and Oldenzaal to Germany (Hannover and Berlin). This railroad connects East Netherlands with Germany, Scandinavia and Eastern Europe. High Speed Line / ICE The High Speed Line (HST) train is bound to become a major instrument for traveling throughout Europe this century. TGV, Eurostar, Thalys and ICE bring nations and cities together, within a few hours traveling. This train stops at the city of Arnhem, while the intercity trains stop in Hengelo. Travel times to f.e. Frankfurt is only 2:30 hour and Amsterdam 1:10 hour. This will ensure even better connection to main European economic centers. Freight train “Betuwe-route” In the beginning of 2008 the Betuwe Route started operating. High Speed Line This technological advanced track the Port of Rotterdam to the German Ruhr-area and the rest of Eastern Europe. Not just the carriers and shipping companies, but also a large part of the Dutch economy benefit from the ability to transport goods straight off and without stopping from the coast to the German border and further on into Europe. The competitive position of Rotterdam and the Netherlands as a shipping and distribution country will be unquestionable strengthened. Plans to develop a rail terminal in the middle of the Arnhem Nijmegen area, are well underway. This terminal creates a direct rail link between the Arnhem Nijmegen area and Eastern Europe. It is evident that the already highly valued logistical attractiveness of this area will improve even further. 62 Air transportation Amsterdam Airport Schiphol Amsterdam Airport Schiphol is a one to two hour drive from East Netherlands. 49.8 million passengers pass through the gates of this airport in 2011 and more than 1.5 million tons of freight is transported. Schiphol offers the professional services of a world-class air hub together with seamless linking with the rest of Europe through outstandingly managed transport links. Düsseldorf International Düsseldorf International, is located on 115 km (72 miles) from Nijmegen. Regularly Düsseldorf International is rated as the number one airport in Germany. From Düsseldorf one can travel to 59 countries with 180 destinations. In 2011 more than 20 million passengers passed the gates of this airport. Düsseldorf International is the third largest airport in Germany. Airport Weeze Airport Weeze (less than 50 km (31 miles) from Nijmegen) commenced operations in May 2003 with regularly scheduled airline services. Situated on highway A57 near Kleve, this airport has been designed for low-cost airlines to operate efficiently in a modern and attractive environment. Airport Weeze is easily accessible and is an inexpensive alternative for approximately 11 million Dutch and German business travellers and tourists alike. The number of passengers in 2011 has risen to 2.4 million. Airport Münster-Osnabrück Airport Münster-Osnabrück (Germany, 70 km (44 miles) from Enschede), offers direct air connections to Berlin, Dresden, Frankfurt, Leipzig, Munich, Nürnberg, Stuttgart, London, Paris, Prague and Zurich. There are also charter flights to several foreign destinations. The number of passengers in 2009 has exceeded almost 1.4 million. Enschede Airport Twente Enschede Airport Twente is located between the three most important cities in Twente, a region in the east of the Netherlands: Enschede, Hengelo and Oldenzaal. It is designed to serve the three primary interests of these three cities, respectively: Enschede and Hengelo for passenger traffic; Oldenzaal and Hengelo for air freight and logistics. Enschede Airport Twente is like-rated with Amsterdam Airport Schiphol, which allows lower tariffs, but without the delay of severe traffic congestion that is found at Schiphol. The Area Development Twente (ADT) is working to convert Enschede Airport Twente's current military designation to full commercial civil aviation. This process should be complete by the end of 2014, and the airport is expected to be fully operational for all types of traffic at that time. Waterways The Netherlands has had a longstanding history of carrying international trade over water. Even inland you currently see a strong reliance on water transport. The rivers Waal, Rhine and Lek cross East Netherlands. These rivers are being used by inland shipping for carrying freight from the Port of Rotterdam to the German Ruhr-area and back. The Twente Canal (up to 2,000 tons), with a tributary to Almelo, links Hengelo/Enschede with the IJssel River. The IJssel River is the connection between the Rhine and the IJssel Lake (formerly the Zuider Zee). Serviceable ports, such as Kampen, Zwolle and Deventer, are located on the IJssel Lake's southern shore. The nearest major ports are Rotterdam and Amsterdam. Rotterdam, being the world’s largest port, can be an ideal gateway to receiving goods coming from all over the world. 63 Distances (km) East Netherlands: number of people within Radius of 500 km > 120 million people Radius of 1,000 km > 325 million people Source: Oost NV, 2012 64 Economic Structure East-Netherlands Number of Personnel in East-Netherlands, 1-1-2012 Netherlands East-Netherlands Agriculture 220,620 51,240 Industry 812,310 184,340 Public utilities 69,610 14,120 Construction 475,480 101,640 Trade 1,423,020 272,620 Transport & Storage 414,520 65,750 Hotel & Catering 352,530 65,770 Information & Communication 261,410 34,100 Financial services 232,710 29,020 Business services 1,174,300 199,290 Public 434,630 78,010 Education 543,200 105,980 Health care 1,311,700 271,670 Other 358,730 59,850 Total 8,084,740 1,533,420 Gelderland 28,990 109,970 9,940 62,130 170,300 42,630 42,130 24,050 20,350 135,780 51,660 67,140 182,990 41,460 989,540 Overijssel 22,250 74,370 4,180 39,510 102,320 23,120 23,640 10,050 8,670 63,510 26,350 38,840 88,680 18,390 543,880 Number of Personnel per region in East-Netherlands, 1-1-2012 Agriculture Industry Public utilities Construction Trade Transport & Storage Hotel & Catering Information & Communication Financial services Business services Public Education Health care Other Total Achterhoek Arnhem/ Nijmegen North Overijssel Twente Veluwe SW Gelderland SW Overijssel 9,710 30,380 1,290 12,800 33,990 7,350 8,610 3,040 2,050 16,440 5,510 11,200 34,410 6,750 183,520 4,430 31,780 5,640 15,760 54,460 13,900 15,350 8,460 7,490 55,400 19,420 28,410 76,560 15,420 352,460 8,870 20,910 2,250 13,560 31,600 10,220 8,020 3,470 3,720 20,470 11,340 13,860 28,780 6,230 183,290 9,570 43,710 1,450 21,990 58,320 10,700 12,670 4,760 4,120 33,450 12,700 20,650 45,960 9,710 289,770 8,670 35,120 2,180 24,560 59,530 12,680 14,320 9,130 9,690 47,430 24,230 22,010 59,270 14,620 343,430 6,180 12,690 830 9,010 22,320 8,700 3,860 3,430 1,130 16,510 2,510 5,530 12,760 4,680 110,130 3,810 9,760 480 3,970 12,400 2,190 2,960 1,820 830 9,590 2,310 4,320 13,950 2,450 70,830 Source: Lisa, July 2013 65 Office and manufacturing rents in the Netherlands Office Rents 2012 (€ per m2) 450 400 400 350 300 250 220 175 200 150 100 130 70 130 70 125 135 90 80 60 135 185 210 175 140 85 90 90 85 80 90 85 50 Amsterdam Utrecht Den Haag Zwolle Arnhem Nijmegen Apeldoorn Ede Enschede Hengelo Deventer Almelo 0 Manufacture rents 2012 (€ per m2) 80 70 65 70 65 70 65 60 55 60 55 50 55 50 45 50 37 40 30 30 25 25 30 25 30 25 25 30 30 25 20 10 Amsterdam Utrecht Den Haag Zwolle Arnhem Nijmegen Apeldoorn Ede Enschede Hengelo Deventer Almelo 0 Source: DTZ Zadelhoff, January 2012 66 Number of Students and Graduates in East Netherlands Number of Students per Study, 2010 Secondary School Netherlands Overijssel Gelderland North Overijssel South West Overijssel Twente Veluwe Achterhoek Arnhem/Nijmegen South West Gelderland Total 939,629 65,844 118,219 21,054 8,731 36,059 39,605 24,102 39,612 14,900 1,307,755 Professional School Vocational Professional School Apprenticeship Higher Professional Education Scientific Education 358,184 28,442 43,712 9,588 3,702 15,152 14,256 9,262 15,459 4,735 502,492 172,174 12,472 21,896 3,735 1,543 7,194 7,418 4,250 7,104 3,214 240,910 416,934 30,186 45,902 10,089 3,876 16,221 13,971 7,031 20,774 4,126 569,110 241,686 10,297 25,260 1,463 702 8,132 7,904 1,208 15,004 1,144 312,800 Number of Graduates per Study, 2009 Secondary Professional School School MBO Netherlands 168,369 197,407 Overijssel 12,236 16,172 Gelderland 21,640 24,760 North Overijssel 4,006 5,168 South West Overijssel 1,596 2,025 Twente 6,634 8,979 Veluwe 7,139 8,138 Achterhoek 4,596 5,512 Arnhem/Nijmegen 7,076 7,997 South West Gelderland 2,829 3,113 Total 236,121 279,271 Bachelors HBO/WO Masters WO 62,054 4,664 6,757 1,548 653 2,463 2,114 935 3,220 488 84,896 30,197 1,154 3,264 201 95 858 1,085 162 1,909 108 39,033 Source: CBS/Stattline, November 2012 67 Unemployment A large pool of labor, also with relatively high education, is available. Unemployed per 1.1.2013 Education Level Netherlands Grade School VMBO Lower Vocational HAVO/VWO Higher Vocational MBO General Higher Vocational HBO Bachelor Professional Vocational WO Master University 148,523 105,012 East Netherlands 26,582 19,852 Province of Gelderland 16,456 12,294 Province of Overijssel 10,126 7,558 23,495 3,666 2,359 1,307 52,205 9,304 5,663 3,641 72,831 13,171 8,126 5,045 29,657 4,567 3,269 1,298 UWV - regions Unemployed per 1.1.2013 per Region Education Level Achterhoek Food Valley (incl. Utrecht) 1,783 1,766 Grade School VMBO Lower 1,809 1,263 vocational HAVO/VWO Higher vocational 202 276 MBO General 993 641 Higher vocational HBO bachelor Professional 1,177 896 vocational WO master 243 425 University Unemployed per 1.1.2013 per Region Education Level Twente Stedendriehoek (incl. Flevoland) 7,022 4,740 Grade School VMBO Lower 4,835 3,370 vocational HAVO/VWO 789 679 Higher vocational MBO General 2,202 1,644 Higher vocational HBO bachelor Professional 2,770 2,429 vocational WO master University 718 715 Midden Gelderland 4,084 Rivierenland 1,697 Zuid Gelderland (incl. Limburg) 3,714 2,874 1,326 2,465 610 199 614 1,267 2,076 569 968 683 1,589 259 1,162 707 IJsselvecht (incl. Drente) 2,495 2,367 328 1,299 1,782 396 Source: www.werk.nl/werkgevers 68 Labor cost in East-Netherlands The cost of labor in the east of the Netherlands is significantly lower than the average of the Netherlands. This is partly attributable to the lower cost of living. This lower cost exists even among wage grades that are governed by Collective Labor Agreements (CLA). Wages, 2009 The Netherlands East Netherlands Gelderland Overijssel North Overijssel Southwest Overijssel Twente Veluwe Achterhoek Arnhem-Nijmegen Southwest Gelderland Number of jobs (* 1.000) 7.812 1.425 520 906 174 68 279 314 162 330 100 Wages (* € Millionen) 298.517 51.435 18.314 33.121 6.202 2.272 9.840 11.474 5.966 12.105 3.576 Wage per job (€) 38.213 36.095 35.219 36.557 35.644 33.412 35.269 36.541 36.827 36.682 35.760 Source: CBS/Statline, November 2012, Oost NV Wage per job, 2009 39.000 38.000 37.000 35.000 34.000 33.000 32.000 Soutwest Gelderland ArnhemNijmegen Achterhoek Veluwe Twente Southwest Overijssel North Overijssel Overijssel Gelderland East Netherlands 31.000 The Netherlands € 36.000 69 East Netherlands Development Agency Strengthening and stimulating the economy of the provinces of Gelderland and Overijssel. In short, this is the mission of the East Netherlands Development Agency (Oost NV). Oost NV plays an important role in executing the economic policies of the Dutch government and the Provinces of Gelderland and Overijssel and its various city governments. To achieve this it is necessary to encourage a close cooperation between businesses, regional institutes, knowledge institutes, and intermediaries. Oost NV acts as a bridge between government, companies and knowledge institutes. Oost NV helps entrepreneurs to innovate, invest and internationalize: Supports organizations in expanding their businesses to the east of the Netherlands Gives a boost to international companies, start-ups and growing SMEs The activities of these four divisions of Oost NV are as follows: Innovate Regional Development & Innovations both initiates and stimulates activities that lead to a better production and business climate for entrepreneurs. One example is the establishing of knowledge and innovation clusters where businesses and knowledge institutes can interact. Another is the setting up of sector-oriented knowledge centers and activities focused on strengthening a company’s knowledge sharing infrastructure. The role of Development and Innovation is namely one of a process manager who, through intensive guidance and coaching, helps guide projects to reality. (Business) Infrastructure This new branch will coordinate infrastructure renewal projects in existing industrial parks, which are designed improve the quality of doing business. It will also work to develop new business and knowledge parks as well as establishing and developing collective business centers. International Business Development works to attract new businesses and/or new business activities. It supports the businesses of the provinces of Gelderland and Overijssel by supporting expansion activities and setting up cooperative networks. Invest The Participation Company East Netherlands NV (PPM Oost) takes part in capital investments in companies in the provinces of Gelderland and Overijssel. The company will take part in the opportunity rich businesses environment that exists in the east of the Netherlands. Especially interesting for PPM Oost NV are the high-tech and mature companies as well as infrastructure creating activities. Oost NV exists since June, 2003 and is a result of a merger of the former OOM (Regional Development Agency for Overijssel) and GOM (Regional Development Agency for Gelderland). Website: www.oostnv.com 70