East Netherlands - Oost NV | East Netherlands Development Agency

Transcription

Sector Profile
High Tech: Nano Technology
East Netherlands
2013/2014 version3
Albert Hoogeveen
East Netherlands Development Agency
P.O. Box 5518
NL-7500 GM Enschede
Telephone
+ 31 (0) 53 851 68 51
E-mail
[email protected]
Internet
www.oostnv.nl
July, 2013
© Oost NV
The East Netherlands Development Agency (Oost NV) has provided the information contained herein for the sole use of our client. We request that it be used
for information purposes only, and not be copied, reproduced, or in any other form distributed, either in part or in whole, without the express written consent of
Oost NV. Oost NV assumes no direct or implied liability for the information contained herein
Welcome
to the Nanotechnology hot spot- East Netherlands
East Netherlands is a dynamic environment in which to start or grow your high tech business. We are
pleased to present a collection of profiles that demonstrates the best of what this region has to offer
when it comes to nanotechnology research, engineering and business. There are few places in the
world that combine such an established and reputable scientific environment, an energizing and
technologically driven business climate, and a unique combination of nature, history, and culture that
guarantees an outstanding quality of life.
Part One of this report presents universities, research institutes, programs and networks in the field of
nanotechnology. Part Two of this report provides more general information about East Netherlands.
We invite you to see for yourself how your company can benefit from such a technologically innovative
environment. It would be our pleasure to be your host and show you the best of what East
Netherlands has to offer.
Yours sincerely,
Foreign Investments Senior Project Manager
A. Hoogeveen MBA
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Factsheet: Nano Technology in East Netherlands
Introduction
East Netherlands is the place where science meets business. East Netherlands is the breeding ground
of many initiatives in the field of nanotechnology. East Netherlands is home to one of the leading
knowledge institutes in nanotechnology in the world, called MESA+. In addition many other education
programs and research institutes in nanotechnology are located in East Netherlands. Oost NV, the
East Netherlands Development Agency, is strongly supporting the initiatives geared towards
nanotechnology and is closely working together with MESA+ and other parties on the various
initiatives in the Netherlands.
Universities
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University of Twente: # 1 in IT
Wageningen University (food, animal, environment, agrotechnological sciences)
Radboud University Nijmegen (a.o. University Medical Centre St. Radboud)
Nanotechnology Related Research Institutes
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MESA+. The institute employs 500 scientists, of which 275 PhD students and postdocs. MESA+
strategic research orientations are BioNanotechnology, Cell-Stress, MesoFluidics,
NanoElectronics, NanoFibrication and Molecular Photonics.
Institute for Molecules and Materials. Fundamental and application-oriented research in the field of
molecular functional structures and functional materials of nanometer dimensions.
Top Institute Food and Nutrition. Scientific breakthroughs in food and nutrition, resulting in the
development of innovative products and technologies that respond to consumer demands for safe,
tasty and healthy foods.
Plant Research International. Strategic and applied research in genetics and reproduction,
genomics, proteomics, metabolomics, bioinformatics, crop protection, crop ecology and
agrosystems.
The Wageningen Bionanotechnology Centre is active in the fundamental science and technology
of micro- and nanosystems and their applications in food and health.
The High Field Magnetic Laboratory is committed to research in the highest available magnetic
fields. 33T magnets are available, a 38T resistive magnet and a 45T hybrid magnet are under
development
NanoLab Nijmegen makes new developments in nanotechnology, in particular Scanning Probe
Microscopy, accessible for small-and medium-sized companies.
High Tech Factory is a shared production facility for products based on microsystems and
nanotechnology.
Nanotechnology Programs & Projects
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High Tech Factory is the latest production location partnered with the MESA+ Institute for
Nanotechnology at the University of Twente. High Tech Factory offers companies space, facilities
and high-value cleanrooms. In addition, entrepreneurs have available to them the possibility to
apply for funding: the High Tech Fund.
TOP program. With providing knowledge and financing, this program for students and staff of the
University of Twente can be credited for the launching of many new products and businesses in
the market.
NanoNextNL is a consortium of more than one hundred companies, universities, knowledge
institutes and university medical centres, which is aimed at research into micro and
nanotechnology
NanoLabNL is a Dutch national facility for nanotechnology research. NanoLabNL offers the use
of their facilities and expertise to universities, research institutes, start-ups and industry.
Companies with a Focus on Nanotechnology
EastNetherlands hosts many nanotechnology related companies like NXP, Sensata, PANalytical,
Micronit, Nanomi, Nanosens, Pentair (Norit), Thales, SenzAir and many others.
East Netherlands is the #1 location for companies and research institutes in nanotechnology.
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Fact Sheet: East Netherlands
General
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East Netherlands, formed by the provinces of Gelderland and Overijssel, is located on the
German border and is situated on major European highways. Highway A1 for example links
Western Netherlands to Northern and Eastern Europe and intersects the region. Highway A12 and
A15 connects the Netherlands with the Ruhr-area (Germany).
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Traffic density is relatively light: traffic flows freely.
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East Netherlands has more than 3,000,000 inhabitants. Major cities are Apeldoorn, Arnhem, Ede,
Enschede, Nijmegen and Zwolle (more than 100,000 inhabitants).
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Airport Amsterdam is just a one to two hour drive from East Netherlands, also reachable by direct
train links. Airport Münster-Osnabrück (Germany) is only 44 miles from Enschede. Airport
Düsseldorf is approximately 72 miles from Nijmegen.
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Attractive cost base
- Low cost structure
- Affordable office and distribution space
Personnel in East Netherlands
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Large pool of qualified people
- Relatively easy to attract personnel
- Lower wages compared with many other regions in Europe
- Multi-lingual
- Highly productive
- Strong work ethic
- International experience and outlook
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Flexible - 24 hour / 7 days per week if needed
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Education
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Highly educated workforce
World-class universities
Technical University of Twente, Enschede
Wageningen University (food, animal, environment, agrotechnological sciences)
Radboud University Nijmegen (a.o. University Medical Centre St. Radboud)
Many Universities of Professional Education
Standard of living
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Beautiful green surroundings and plenty of open space to work, live, and play. Several large
nature parks and many historical villages.
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Relatively low site and construction costs.
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East-Netherlands has leading medical facilities.
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East-Netherlands has low crime-rates and a high level of satisfaction with city fire and police
services.
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Table of Content
Welcome to the Nanotechnology hot spot- East Netherlands ................................................................ 2
Factsheet: Nano Technology in East Netherlands .................................................................................. 3
Fact Sheet: East Netherlands.................................................................................................................. 4
Part 1: Nano Technology in East Netherlands
Universities
University of Twente ................................................................................................................................ 9
Radboud University Nijmegen ............................................................................................................... 11
Wageningen University and Research Centre ...................................................................................... 12
Related Research Institutes
MESA+ Institute for Nanotechnology .................................................................................................... 13
Institute for Molecules and Materials ..................................................................................................... 15
Top Institute Food and Nutrition ............................................................................................................ 16
Plant Research International ................................................................................................................. 18
Wageningen BioNanotechnology Centre .............................................................................................. 19
High Field Magnet Laboratory (HFML) .................................................................................................. 20
NanoLab Nijmegen ................................................................................................................................ 21
High Tech Factory ................................................................................................................................. 22
Programs & Projects
Top Program Overijssel: Support for Entrepreneurs Top Placement................................................... 23
NanonextNL ........................................................................................................................................... 24
VentureLab International & Soft Landing .............................................................................................. 24
UT International Ventures ...................................................................................................................... 26
Networks
Kennispark Twente: an innovative place for knowledge-intensive companies ..................................... 27
Technology Circle Twente (TKT) ........................................................................................................... 28
MinacNed............................................................................................................................................... 29
Locations
Kennispark Innovation Campus............................................................................................................. 30
Mercator Technology & Science Park ................................................................................................... 32
Company Profiles
3T ........................................................................................................................................................... 34
Aquamarijn Micro Filtration .................................................................................................................... 34
AeroTech Development ......................................................................................................................... 35
Blue4Green............................................................................................................................................ 35
Bronkhorst High-Tech............................................................................................................................ 36
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Cameron Health .................................................................................................................................... 36
Dannalab ............................................................................................................................................... 37
Delta Mask ............................................................................................................................................. 37
Demcon ................................................................................................................................................. 38
eMALDI .................................................................................................................................................. 38
Encapson ............................................................................................................................................... 39
IBIS Technologies ................................................................................................................................. 39
IMS ........................................................................................................................................................ 40
Inertia ..................................................................................................................................................... 40
LioniX ..................................................................................................................................................... 41
MASER Engineering .............................................................................................................................. 41
Medimate ............................................................................................................................................... 42
Medspray ............................................................................................................................................... 42
MicroCreate ........................................................................................................................................... 43
Microflown Technologies ....................................................................................................................... 43
Micronit .................................................................................................................................................. 44
Mosaic Systems .................................................................................................................................... 45
MyLife Technologies .............................................................................................................................. 45
Nanomi .................................................................................................................................................. 46
NanoPhysics .......................................................................................................................................... 46
Nanosens............................................................................................................................................... 47
NXP ....................................................................................................................................................... 47
Nymus 3D .............................................................................................................................................. 48
Optisense............................................................................................................................................... 48
Ostendum .............................................................................................................................................. 49
PANalytical ............................................................................................................................................ 49
Pentair X-Flow (former Norit X-Flow) .................................................................................................... 50
PhoeniX software .................................................................................................................................. 50
Relitech .................................................................................................................................................. 51
Satrax .................................................................................................................................................... 51
Sensata Technologies Holland .............................................................................................................. 52
Sentron Europe ..................................................................................................................................... 52
SenzAir .................................................................................................................................................. 53
SmartTip ................................................................................................................................................ 53
SolMateS ............................................................................................................................................... 54
Tide Microfluidics ................................................................................................................................... 54
Thales Nederland .................................................................................................................................. 55
Twente Solid State Technology (TSST) ................................................................................................ 55
U-Needle................................................................................................................................................ 56
VDL Enabling Technologies Group ....................................................................................................... 56
WieWeb Software .................................................................................................................................. 57
XiO Photonics ........................................................................................................................................ 57
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Part 2: General information East Netherlands
East Netherlands in Figures .................................................................................................................. 60
Infrastructure in East Netherlands ......................................................................................................... 61
Economic Structure East-Netherlands .................................................................................................. 65
Office and manufacturing rents in the Netherlands ............................................................................... 66
Number of Students and Graduates in East Netherlands ..................................................................... 67
Unemployment....................................................................................................................................... 68
Labor cost in East-Netherlands ............................................................................................................. 69
East Netherlands Development Agency ................................................................................................ 70
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Part 1: Nano Technology
in East Netherlands
8
Universities
University of Twente
The University of Twente is a young, entrepreneurial university. It sets standards in the field of new
technology and seeks to stimulate change, renewal and progress in society. The university works with
the technologies of the future - information technology, biotechnology and nanotechnology - in which
behavioural and social science research play a vital role. The University of Twente is active in areas
such as health, water, sustainability, security and education.
Faculties
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Behavioral Sciences (BS)
School of Management and Governance (SMG)
Engineering Technology (CTW)
Electrical Engineering, Mathematics and Computer
Science (EEMCS)
Science and Technology (TNW)
International Institute for Geo-Information Science
and Earth Observation (ITC)
Research
The University of Twente’s is accommodated in six successful research institutes.
The following matrix displays the interrelation between faculties and institutes.
Faculties
INSTITUTES
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MESA
MIRA
CTIT
IGS
TNW
x
x
EEMCS
x
x
x
CTW
x
x
x
x
BS
x
x
x
SMG
x
x
x
x
Centre for Telematics and Information Technology
Institute for Innovation and Governance studies
Institute for Nanotechnology
Institute of Mechanics, Processes and Control Twente
Institute for Biomedical Technology and Technical Medicine
Institute for Behavioral Research
The institutes combine scientific excellence with a constant search for real innovation and applications
for society, and have successfully instigated many spinoff activities. Science relies on talent, and the
UT wants attract that that talent by offering high quality research environments and opportunities for
junior and senior researchers. The UT attracts talent through the Graduate School, tenure tracks, and
additional space and funding for excellent projects.
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The University of Twente actively promotes entrepreneurship among its students and staff through
various programmes. Kennispark Twente is the main vehicle for the promotion of entrepreneurship
and the commercialization of knowledge.
In 20 years over 700 companies have originated from the university. Many were launched with the
TOP programme (Temporary Entrepreneurial Positions), providing basic funding and coaching. These
companies have a 5-year survival rate of over 70%, leading to almost 10,000 jobs to date.
Furthermore, the university has about 130 student-run companies.
For more information: http://www.utwente.nl/en/
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Radboud University Nijmegen
Radboud University Nijmegen is one of the leading academic
communities in the Netherlands. Established in 1923 and situated
in the oldest city of The Netherlands, it has seven faculties and enrols over 19,000 students in 107
study programs (40 Bachelor’s and 67 Master’s programmes).
An international dimension is an essential aspect of the quality of the university’s education and its
research and is an integral part of the university’s identity.
Radboud University Nijmegen´s seven faculties are:
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Faculty of Philosophy, Theology and Religious Studies
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Faculty of Arts
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Faculty of Law
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Faculty of Social Sciences
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Faculty of Medical Sciences
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Faculty of Science
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Nijmegen School of Management
International Relations
Radboud University Nijmegen engages in various forms of cooperation in order to develop and
strengthen the international character of the university. Staff are internationally orientated and are
encouraged to collaborate with partners from abroad.
Research
The research of Radboud University Nijmegen covers a wide range of disciplines. The university is not
only strong in the field of life sciences, but also in law, language, and literature. Its
high-quality research institutes, which rank at the forefront of a number of fields, offer unique
opportunities to undergraduates, postgraduates and PhD students alike.
Research institutes
Radboud University has grouped its research within research institutes with the aim of creating an
optimal research environment which has good focus and a critical mass. Radboud University has
several major research institutes.
One of Radboud University’s distinguishing hallmarks its emphasis on interdisciplinarity. The current
size of the University and its academic breadth provide the conditions for interdisciplinary cooperation, where new ideas can emerge. For example, at the Nijmegen Centre of Molecular Life
Sciences (NCMLS), biomedical experts, medical scientists, biologists, physicists, and bioinformaticians work together.
Labs and facilities
The numerous labs and facilities are available to students, faculty, staff and researchers throughout
the campus and are also available to scientists from outside the university.
For more information: www.ru.nl
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Wageningen University and Research Centre
Mission: “To explore the potential of nature to improve the quality of life”
Wageningen University and Research Centre (Wageningen UR)
provides education and generates knowledge in the field of life
sciences and natural resources. The domain of Wageniningen
UR consists of three related core areas:
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Food and food production
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Living environment
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Health, lifestyle and livelihood
This combination of knowledge and experience enables Wageningen UR with its 6,500 staff and
10,000 students to contribute actively to solving scientific, social and commercial problems in the field
of life sciences and natural resources. Wageningen UR approaches these national and international
issues from the perspectives of various disciplines, with an integrated approach and in close
collaboration with governments, companies, stakeholder organizations, citizens, and other knowledge
institutions. Wageningen UR pays attention to the balance between three priorities in society:
economics, culture and nature.
Wageningen UR has branches all over The Netherlands (and in China and Brazil, by the way). A large
number of lecturers, researchers and other employees are based at Wageningen Campus.
Research; Areas of expertise
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Nutrition and health
Food production
Biobased economy
Coast & Sea
Nature and landscape
Climate and water
Market and chain strategies
Research Institutes
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Alterra
Central Veterinary Institute
Centre for Development Innovation
Food & Biobased Research
IMARES
LEI
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Livestock Research
Applied Plant Research
Plant Research International
RIKILT
Wageningen UR Greenhouse Horticulture
The strength of Wageningen UR lies in its ability to join the forces of specialised research institutes
and Wageningen University.
Education
Wageningen University offers scientific education. Students get the opportunity to combine the pure
sciences – from plant sciences to food technology and health – with the social sciences – from
environmental studies to economics and sociology.
For more information: www.wageningenur.nl/uk
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MESA+ Institute for Nanotechnology
MESA+ is one of the largest nanotechnology research institutes in the
world, delivering competitive and successful high quality research. It
uses a unique structure, which unites scientific disciplines, and builds fruitful international cooperation
to excel in science and education. MESA+ has created a habitat for start-ups in the micro- and nanoindustry to establish and to mature.
MESA+, Institute for Nanotechnology, is part of the University of Twente and cooperates extensively
with various research groups within the University. The institute employs 500 people of which 275 are
PhD’s or postdocs. With its NanoLab facilities the institute holds 1250 m2 of cleanroom space and
state of the art research equipment. MESA+ has an integral turnover of 45 million euro per year of
which 60% is acquired in competition from external sources.
The structure within MESA+ supports and facilitates the researchers and stimulates cooperation
actively. MESA+ combines the disciplines of physics, electrical engineering, chemistry and
mathematics. Internationally appealing research is achieved through this multidisciplinary approach. It
is strengthening its international academic and industrial network by fruitful cooperation programs.
MESA+ focuses on nanotechnology based on its underlying strengths in materials science,
microsystem technology, bottom-up chemistry, optics and systems.
Its mission is:
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to excel in its field of science and technology;
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to educate researchers and designers in the field;
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to build up fruitful national and international cooperation with industry and fellow institutes.
Within MESA+, different faculties combine their strengths within the following disciplines:
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Electrical Engineering, Mathematics and Computer Science (EEMCS);
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Sciences and Technology (S&T)
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Faculty of Management and Governance (FMB: Faculteit voor Management en Bestuur)
The MESA+ research programs are directly
related to the national research program
NanoNed. In NanoNed the importance of a
national facility has been acknowledged, and a
major part of the effort and the accompanying
budget is dedicated to NanoLab NL. NanoLab NL
has the aim to build up, maintain and provide a
coherent and accessible high-level, state-of-theart infrastructure for nanotechnological research
and innovation in the Netherlands. NanoLab NL is
about national cohesion in infrastructure, access,
and tariff structure. MESA+ is proud to be part of
the national consortium NanoLab NL.
MESA+ NanoLab plays a central part in collaborations with industry. MESA+ has a strong relationship
with industry, both through joint research projects with the larger multinational companies, and through
a cooperation policy focused on small and medium- sized enterprises. The Institute maintains an
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extensive international network. It cooperates and exchanges researchers with other leading
international nanotechnology institutes.
For more information: www.mesaplus.nl
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Institute for Molecules and Materials
IMM is an interdisciplinary Graduate Research School within the Faculty of Science. Its mission is to
conduct research and train graduate students in the design, study, and manipulation of the properties
of functional molecules and materials. It organizes the coordinated effort by chemists, physicists and
biological chemists of IMM to carry out fundamental and application-oriented research in the field of
molecular functional structures and functional materials of nanometer dimensions.
IMM is a highly interdisciplinary research institute comprised of 19 research groups active in areas
ranging from condensed matter science to (bio)chemical synthesis. The institute has
unique experimental facilities.
Research Facilities
The IMM exhibits a multitude of advanced spectroscopic tools that, on their own, allows for a detailed
characterization of molecules and materials in the nano-domain. Yet, real breakthroughs are to be
anticipated when such tools are combined to investigate systems simultaneously with respect to
different properties.
The research facilities at IMM:
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HFML (director prof. J.C. Maan)
NMR (under supervision of prof. A. Kentgens)
FELIX, FELICE & FLARE (under supervision of prof. W. van der Zande/dr. L. van der Meer)
Nanolab (under supervision of dr. Hans Elemans)
Trace Gas Facility (under supervision of dr. Frans Harren)
For more information: www.ru.nl/imm
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Top Institute Food and Nutrition
TI Food and Nutrition is a public private partnership of science,
industry and government conducting strategic research in food and
nutrition. Its partners are key players in the global food industry and
include twenty-six leading food and ingredient manufacturers and
personal care companies and respected research institutes and universities including medical centres.
TI Food and Nutrition also partners in several European research programmes in the areas of food,
nutrition and genomics. Its annual turnover is €25 million.
TI Food and Nutrition plays a major role in providing its industry partners with leads for the development
of new, healthy foods with regard to major health concerns such as obesity and metabolic syndrome.
Another focus lies on generating a knowledge base for use in developing fermented foods with improved
functionality and which may target microbial activity in the gastrointestinal tract. TI Food and Nutrition is a
major player in the Dutch government’s Innovation Areas Programme. The government defined these
areas as key for economic growth and investment and has the goal of maintaining and expanding the
Netherland’s position as the leading innovation area in food and nutrition.
Research
The themes of TI’s research include:
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Nutrition and Health
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Sensory and Structure
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Bioingredients and Functionality
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Cardiovascular Health
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Functional Fermentation
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Food Structuring
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Gastrointestinal Health
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Food Chain Sustainability and Dynamics
Sensory-Liking
Food Safety and Preservation
Texture-Taste
Weight Management
Oral Health
Muscle Health and Function
The three cross-theme platforms are:
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Nutrigenomics
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Bacterial Genomics
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Knowledge Management
Partners
TI Food and Nutrition industrial partner organizations
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Cargill
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CBL
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Chr. Hansen
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CRV
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CSK food enrichment
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CSM
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Danone
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DSM
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Federatie Nederlandse Levensmiddelen
Industrie (FNLI)
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FrieslandCampina
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Fromageries Bel
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GlaxoSmithKline
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Kellogg Company
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Nestlé
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PepsiCo
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Philips Research
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Productschap Zuivel
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Unilever
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VION Food Group
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Wrigley
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TI Food and Nutrition partner research institutes:
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ACTA Dental Research
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Groningen University / UMCG
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Maastricht University / MUMC+
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NIZO food research
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TNO
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Wageningen University and Research Centre
For more information: www.tifn.nl
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Plant Research International
Through the combination of know-how and experience across
the entire spectrum of plant research, Plant Research
International offers unique new perspectives for governments
and private companies, for agriculture and horticulture, and
for rural and environmental development.
Plant Research International is part of Wageningen University and Research Centre (Wageningen
UR).
Plant Research International is focused on four important scientific, social and economic themes:
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Plant-based raw materials
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Health
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Sustainable production and climate change
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Systems biology
Innovative
Plant Research International offers innovative products: from DNA to complete agricultural production
systems. Based upon their wide range of scientific qualities, Plant Research International offers their
clients truly unique solutions.
World wide
Plant Research International’s clients and partners come from all parts of the world. Their products
offer competitive advantages, improving the position of companies and enabling governments to
further develop and execute policies for a sustainable economy.
Research Facilities
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Unifarm
Organic Experimental and Training Farm Droevendaal
Laser technique for measuring droplet size spectrum
Imspector for mobile measurement of crop characteristics
Marker-free technology
Spraying laboratory
Wageningen Omics Facility
For more information: www.pri.wur.nl/uk
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Wageningen BioNanotechnology Centre
The Wageningen Bionanotechnology Centre (BioNT)
is active in the fundamental science and technology
of micro- and nanosystems and their applications in
food and health. The center helps companies to
utilize the opportunities of micro- and nanotechnology
to improve food and prevent health problems.
Research themes
Interdisciplinary research teams from Wageningen University & Research Centre closely co-operate
on:
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Chemical biology
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Consumer Behavior and nano perception
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Encapsulation and delivery
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Process innovation
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Sensors and diagnostics
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Structure and texture
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Toxicology and Risk Assessment
Micro- and nanotechnology can make important contributions to the fulfilment of these challenges. It
will allow sensors and diagnostic systems with improved sensitivity and specificity with which food
quality can be assured and processes can be controlled more accurately. Application of micro- and
nanotechnology will make separation and other food processes more efficient and will open up
possibilities for new products. Derived from drug delivery systems envelopes for the delivery of
nutrients can be designed that will improve the uptake by the consumer. Nanoscale control of
structures will allow tailoring the texture of food products to the requirements of consumer groups.
Results of micro- and nanotechnology will have a large impact on packaging and logistics of food.
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Although these results are attainable within the foreseeable future, the combined effort of academia,
research institutions and industry is required to develop them into economically viable concepts.
BioNT, the centre for Applications of Nanotechnology in Food, offers state-of-the art facilities and
expertise on the cross-section of micro- and nanotechnology and food to help industry in these efforts.
For more information: www.biont.wur.nl/uk
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High Field Magnet Laboratory (HFML)
The HFML is committed to generate the highest available continuous
magnetic fields.
33T magnets are available, a 38T resistive magnet and a 45T hybrid magnet are under development.
HFML performs research with these fields and makes them available to qualified external users.
Local research interests are:
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Magnet technology
Soft condensed matter and molecular material
Strongly correlated electron systems and
Semiconductors and nano-systems.
The HFML is a Large European Research Infrastructure and
a Dutch national research facility. It is jointly operated by the
Radboud University Nijmegen and the Foundation for
Fundamental Research on Matter (FOM). The HFML is part
of the Faculty of Science and has close cooperation with the
Institute for Molecules and Materials (IMM) and is sponsored
by the EU for access of external users.
The HFML is an independent research institute with strong scientific relations with the Institute of
Molecules and Materials belonging to the Faculty of Science (which includes physics, chemistry,
biology, informatics and mathematics departments). The connection to the IMM and the Faculty
guarantees the availability of a very wide range of expertise and support in a lively scientific climate.
For more information: http://www.ru.nl/hfml/
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NanoLab Nijmegen
NanoLab Nijmegen was begun as an initiative of the Institute for Molecules
and Materials (IMM) at the Radboud University Nijmegen. It is managed by the research group
Scanning Probe Microscopy in cooperation with five allied nano-research groups from the IMM.
The goal of NanoLab Nijmegen is to make nano-technology and -science researchers and research
apparatus available to small and medium business owners (SMEs).
The arrival of nano-science and -technology has signaled the beginning of a new era where rapid
developments are being made in previously unknown areas. There are already a large number of
applications being developed for business application using nanotechnology. As well, improvements
are also being made in existing processes and products. A few examples of sectors where these
applications are most prevalent are electronics, medicine, energy, construction, sport, chemicals and
cosmetics.
For more than a decade, since 2002, NanoLab Nijmegen has used various means and methods to
make the significant knowledge and experience of the nano-scientists in the region available for
SMEs. Among their services are:




Professional consulting
Access to facilities: by either performing contract research or by allowing direct access to the
labs, SMEs are able to take advantage of the modern facilities that make nano-production and
application possible.
Training: NanoLab Nijmegen also offers training in the apparatus that is necessary for
converting materials to nano.
Education and information services: NanoLab Nijmegen presents information at trade shows,
and provides in-house presentations and laboratory tours for interested business wonders.
For more information: www.ru.nl/nanolab
21
High Tech Factory
High Tech Factory is the latest production location partnered with the MESA+ Institute for
Nanotechnology at the University of Twente. MESA+ is where companies in Microsystems and
nanotechnology can mass produce materials for the commercial market. An exceptional support
system, where entrepreneurship for nanotechnology applications gets a serious boost. Companies are
able to focus on their operations and invest their energy in growth, instead of struggling to arrange the
sometimes messy details of running a business. High Tech Factory offers companies space, facilities
and high-value cleanrooms.
In addition, entrepreneurs have available to them the possibility to apply for funding: the High Tech
Fund. This takes the form of an operational lease for available equipment should banks, private
investors or seed funds not be ready to invest in the company. This allows the company to use
production equipment necessary to ramp up production and to achieve production volume necessary
for profit. What exactly the conditions are and how the fund operates can be found in the High Tech
Fund fact sheet (in Dutch).
Committed companies
Companies that are committed to supporting the High Tech Factory are, among others: Blue4Green
(Enschede), Bronkhorst (Ruurlo), Demcon (Oldenzaal), EnablingM3 (Dordrecht), Encapson
(Nijmegen), IMS (Almelo), LioniX (Enschede), Medimate (Enschede), Medspray (Enschede), Micronit
(Enschede), Nanomi (Oldenzaal), Ostendum R&D (Enschede), PhoeniX (Enschede), SmartTip
(Enschede), SolMateS (Enschede), Twente Solid State Technology (Enschede), UNeedle (Enschede),
UT International Ventures (Enschede) en Xio Photonics (Enschede).
For more information: www.hightechfactory.com (in Dutch only)
22
Programs & Projects
Top Program Overijssel:
Support for Entrepreneurs Top Placement
TOP stands for Temporary Entrepreneurs Placement (“Tijdelijk Ondernemers Plaats” in Dutch), an
arrangement from the University of Twente and the Saxion University of Applied Sciences. For more
than 25 years this arrangement has been helping innovative and entrepreneurial startups to make a
running start. Participating companies have one-year access to a diverse range of support, consulting
networking and financial help in order to have starting their company to be as successful as possible.
For whom?
TOP is intended for knowledge intensive entrepreneurs who generally are coming out of the
sponsoring universities. TOP also encourages entrepreneurs who wish to cooperate with either, or
both, of the institutes.
The requirements of TOP are:






The company is between 0 and 5 years old, inclusive
The business concept is knowledge intensive or innovative
The company has never before made use of the TOP position
The company will be adding value to the economic activity in the region of East Netherlands
Some sort of cooperation is planned with the University of Twente and/or the Saxion
University of
Applied Sciences.
The support
The participant in the TOP placement has access to a number of support possibilities. Assistance in
working out a business plan, insofar as needed. In addition, every TOP company is eligible for a
market scan (desk research) in order to determine the targeted market. There is also more specific
support available:
 Financial support: an interest-free loan from the Rabobank Enschede-Haaksbergen and
accounting support from Deloitte
 Coaching and advice in the area of communication and legal affairs from the Knowledge Park
Twente
 Guidance from the universities in the area of technical expertise, as well as from a business
coach.
Office location
Access to networks, such as the TKT (Technology Network Twente), the Entrepreneurs Club Business
& Science Park, and the New Business Society of the football club FC Twente.
The procedure
Are you interested in a TOP placement? The first step is to make contact with Erwin Holtland
(Coordinator Young Entrepreneurs) at +31 53 489 8989, or [email protected]. He will sit down
with you to determine your eligibility. After this you will be evaluated by the TOP advisory commission.
This commission meets on a monthly basis to examine new applicants, the progress of the program
and the successful conclusion of participants in the TOP placement.
More information www.kennispark.nl (in Dutch language)
23
NanonextNL
NanoNextNL is a consortium of more than one hundred companies, universities, knowledge institutes
and university medical centres, which is aimed at research into micro and nanotechnology. The total
sum involved for NanoNextNL is 250 million euros, half of which is contributed by the collaboration of
more than one hundred businesses, universities, knowledge institutes and university medical centres
and the other half by the ministry of Economic affairs, Agriculture and Innovation.
Micro and nanotechnology will make a significant contribution to resolving major societal questions
such as keeping an ageing society healthy and keeping our environment liveable in a changing
climate. The basis for being able to provide this contribution lies in the creation of an open, dynamic
and sustainable ecosystem for research and innovation with which the Netherlands can continue to
play its leading role in the world, and can extend this role further, in micro and nanotechnology. This
ecosystem is created by initiating and guiding research projects within the themes.
More information www.nanonextnl.nl
VentureLab International & Soft Landing
VentureLab International, formerly Venturelab Twente, provides business development for technologybased start-ups and is a business growth accelerator for well-established companies. VentureLab
believes that the key to launching a company on the market as effectively as possible is not only the
idea, but also all the entrepreneurial competences that form the basis of a successful business
operation. It takes the steps to move from the business idea, to a business model, to running a fast
growing, technology bases business. VentureLab helps businesses to build and grow- something
which they cannot do on their own.
Services
VentureLab International offers a range of services for start-ups
and growth seeking companies. Its business development
program gives access to:
 Weekly training sessions on diverse subjects
 Experts on diverse subjects
 Fifty hours of coaching and progress monitoring
 Facilities such as meeting rooms, conference rooms or
office space free of charge
VentureLab International is open to entrepreneurs and business developers from the Netherlands and
abroad. Foreign trainers and experts are in the programs and the official language is English.
Free events
VentureLab International also offers information meetings, open training sessions and lectures free of
charge. They are held once a month by a renowned speaker from science or industry on a topic
relevant to high-tech and high-ambition business development
VentureLab Soft Landing
Adding an international dimension is now within reach of many companies. It is becoming almost the
same to do business overseas as it is at home, keeping a few things in mind, though. Other countries
have other cultures and regulations. To cope with these differences choosing an entrepreneur-friendly
24
environment is crucial. VentureLab International is located in such an environment and can be your
gateway to Europe.
The home base of VentureLab is Enschede, the Netherlands. VentureLab International offers a full
service pre-incubator programme for technology-based businesses. VentureLab gives access to the
facilities and expertise of the University of Twente and Saxion University of Applied Sciences.
Open innovation is embraced. A variety of networks is available. For business, sciences or services
exclusively, as well as business & science & services platforms. There are mixed and dedicated
incubators specialised in nano technology-related and ICT-related innovation and business
development. The VentureLab partners and other support organisations have longstanding experience
in business development support.
In 2009, the National Business Incubation Association (www.nbia.org) awarded the NBIA Soft
Landings International Incubator designation to VentureLab International. Through its Soft Landings
programme, NBIA recognises incubators that are especially capable of helping nondomestic
companies enter the incubator’s domestic market. VentureLab International joins a select group of
programmes from around the world that have earned the designation since NBIA began the
programme in 2005. VentureLab is the first of only two programmes designated in the Netherlands.
The VentureLab International Soft Landings offer includes access to:

Housing assistance (for business and staff)

Help concerning immigration & visa, import/export laws, obtaining permits and licences

Translation services

Language training

Cultural training

Domestic market research and entry assistance

Capital and potential funders
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Intellectual property protection / patent assistance
For more information: www.venturelabinternational.com
25
UT International Ventures
d/b/a MESA+ International Ventures
Commercializing nanotech and life sciences
MESA+ International Ventures (MIV) is a public-private incubator investment fund with a focus on
+
nanotechnology and life sciences. Together with research groups from the MESA research institute of
nanotechnology of the University Twente, MIV is scouting and screening newly developed
technologies for disruptive market potential. In case a technology screens favourable, a next step in
the MIV commercialization process is embarked on: the market(s) for the technology is/are researched
in precise detail, potential customers are contacted, the technology is developed towards a
demonstrator (proto-type) product and the necessary Intellectual Property Rights (IPR) are secured.
By so doing, a well-informed, thorough business plan for a spin-out company is prepared on which
basis MIV can establish a new company to which it provides the necessary Series A finance.
Subsequently, MIV will guide its portfolio companies towards a first licence deal within a codevelopment framework with one or more multinational partners, or it ensures that additional Series B
capital is raised in the financial markets such that a MIV portfolio company can develop further and
progress towards sustainable profits.
Public-private finance and network
MIV has obtained (share) capital from the University Twente. The financial contribution from the local
province Overijssel is injected in a unique manner, namely as share surplus capital on the University
Twente share in MIV’s holding company. This provides a special kind of Corporate Social
Responsibility: not only will MIV’s portfolio companies provide new technologies for societal needs
(e.g. improved health diagnosis, improved water purification and improved thermal insulation), the
research institute that initiated and financed the bulk of the early technological developments will
benefit significantly from dividends and/or exit money via its 60% (indirect) share of the actual share
that MIV holds in a portfolio company. In this way, a revolving mechanism is offered to the university
for future funding of research.
The remaining finance stems from five private parties and management. All private investors also act
as committed advisors and bring in a relevant network for future spin-out finance and with corporate
leaders of multinational companies that could become off-takers of MIV technology that is
commercialized.
MIV Mission
MIV Vision
MIV Strategy
Transform knowledge into economic good by exploiting and
strengthening the MESA+ technology platforms
Strong positioning at the forefront of the coming nanotech
revolution, creating an entrepreneurial environment by bridging
the gap between technology and markets
Technology




grants
Scout
/mine
Screen
Develop
Public
science
Market






Operations
Analyse 
Screen
Develop
Capture
Brand 
Distribute


Define
specs
Quality
and time
Managem
ent
Qualified
personnel
Finance





Investment in
MIV
Third party
finance
for spin-out
ventures
Subsidies
Value
creation
26
Programs & Projects
Networks
Kennispark Twente: an innovative place for knowledgeintensive companies
Innovation and entrepreneurship are an integral part of the University of Twente in the east of the
Netherlands. Ever since the 1980s the university has made both of these elements an essential part of
institution policy, together with many partners. This has led to where innovation and entrepreneurship
are an inescapable part of the environment, even outside the immediate location of the university
itself. One of these places is Kennispark Twente (‘kennis’ is the Dutch word for knowledge. At
Kennispark Twente there is everything one needs to be successful in entrepreneurship and
innovation.
Entrepreneurship
New ideas and opportunities are being developed at the UT with a focus on high-tech with the human
touch of the social sciences. The university has six research institutes. Teams of business developers
follow the research output of the institutes and, using their knowledge of developments in the market
and the economic potential of these ideas, work to bring them further into the market. This most often
occurs in the form of spin-off companies and in joint research with industry.
In addition, there are a number of education choices that also support entrepreneurship. These vary
from short trainings to a minor in entrepreneurship. There is also a business development support
structure for high-tech, high-ambition entrepreneurs, called Venture Lab International. Coaching and
financial assistance is also available to assist startups.
Innovation
The University of Twente is open for cooperative relationships with the industry. This often occurs
through facility sharing agreements, where companies are invited to use the research facilities and
laboratories of the university. In addition, companies are encouraged to open innovation centers at
Kennispark Twente. A good example of this is the ThermoPlastic Research Center (TPRC) in which
the companies Stork, Ten Cate, Boeing and the university perform research into thermoplastic
composites for the aircraft industry. Another example is the High Tech Factory, where approximately
20 companies together with the UT have established research and production facilities in the areas of
micro- and nanotechnology. The long-standing clean room of the UT is being refurbished for this
purpose.
For small and medium enterprises Kennispark Twente has established so-called portals. Smaller
companies can place research questions on these portals and will be linked to students, student
entrepreneurs, spin-off companies and research groups of the university for the answer. In this way
the knowledge of the university is made accessible for the business community.
For more information on Kennispark: www.kennispark.nl
27
Technology Circle Twente (TKT)
TKT (Technology Kring Twente; 'Kring' meaning Circle and Twente the hi-tech
region in the Netherlands near the German border) is and active network of 180
high tech businesses in Twente aiming at co-operation and the exchange of information.
Combining innovative potential
TKT comprises about 200 high tech and expert businesses in Twente and was set up by the initiative
of Twente University. It primarily targets the enhancement of economical opportunities for its
members.
Members
TKT members are often young, high tech
innovation and product developing
companies; technical businesses
employing between 10 and 25 staff. They
aim at new developments and in their role
of providers of knowledge form a link
between Twente University and business
life. As illustrated by the members’ list on
the website, the members represent a wide
range of technologies.
Aims and activities
TKT primarily aims at promoting her members’ interests by:
 Sharing knowledge, experience and expertise
 Advancing cooperation between members
 Creating members’ market profiles
 Supporting members’ business development
 Strengthening the position of the Twente region as a knowledge area
TKT primarily tries to further project based cooperation.
Joint product development
Member firms have in the past worked together on a number of products and in doing so they have
started to form small, semi-permanent conglomerates. Their flexibility and result driven culture has
produced a string of innovative products and design awards. The TKT has played a major role in these
projects, not as projectmanager but as an enabler. It is at TKT meetings that members meet informally
and discuss projects, prospects, possibilities and problems. Through their long acquaintance members
have come to know and trust others. This trust is crucial in building commercial relationships in
product development because so much remains unsure, even after the most thorough plan has been
hatched.
Bright future
The long history of close cooperation with the University Twente, the informal network and product
development initiatives have culminated in the Knowledge Industry initiative. This should be a strong
basis for future growth. As a technical magazine recently noted, the TKT is the “High Tech palette of
Twente”
For more information visit: www.tkt.org
28
MinacNed
The Microsystems and nanotechnology cluster, shortly
MinacNed, is an association aiming to strengthen the Dutch economic activity based on microsystems
and nanotechnology in the Netherlands. Members are research institutes, equipment manufacturers,
suppliers and users of technological components.
The entire supply chain is represented by this association. MinacNed has about sixty members.
The board of the association consists of eight persons and represents also the scientific research
programs MicroNed and NanoNed. Chairman is Ronny van 't Oever, technical director of Micronit
Microfluidics Enschede.
About three times a year, MinacNed organizes member meetings, with a (prospective) member
hosting the meeting. During these meetings, association business and activities are discussed. Each
meeting will be dominated by lectures about a current topic. In addition, the meetings are an excellent
opportunity to network. New members and members with a new development are given the
opportunity to present themselves or their innovations by an elevator pitch.
For more information: www.minacned.nl
29
Locations
Kennispark Innovation Campus
Kennispark Twente is also a business park/innovation campus for knowledge intensive entrepreneurs.
The Kennispark organization controls the physical development of the regional innovation
infrastructure centered around the University Campus, the Hengelosestraat and the Business &
Science Park Enschede. These area’s blend together into one Innovation Campus. Kennispark
Innovation Campus has been recognized as one of the campuses of national importance.
Kennispark offers facilities dedicated to knowledge intensive entrepreneurs such as office space and
laboratories. Amongst others:
Business & Science Park Enschede
A melting pot of innovative activities where "science" as well as "business" profit from each other,
technologically as well as commercially. The successful BSP formula can be seen as resulting from a
unique location, outstanding facilities, an intensive and active knowledge exchange, and an
atmosphere that encourages mutual beneficial cooperation.
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Value added business location, offices and business services centers
Outstanding infrastructure, public transportation connections (including exclusive train station)
Park-like setting with planned green areas, water sculpture and art objects
Home of the championship FC Twente soccer team, the Arke Stadium, is adjacent the park,
which also houses business centers and has as an amenity a 2000 car capacity parking lot.
BTC Twente
Incubator for companies who want to start small and want to have flexibility with their lease contract.
BTC has several options for offices and specific facilities (labs, warehousing) in several buildings.
High Tech Factory
Shared production facilities for micro- and nanotechnology related companies at the University
Campus.
The Corridor
Building for innovative entrepreneurs with office space and several possibilities for large and small
conferences.
The Gallery
In the framework of creating an inspiring business environment for knowledge intensive companies,
the university and other private parties are redeveloping the university’s longest building into a unique
and multifunctional business center: The Gallery.
The building is located on the edge of the university
campus, across from the adjacent industrial estates, and
will become the centerpiece of the Kennispark Twente
knowledge center. It is the first -and most high-profile - of
the buildings in the area to be dealt with as part of the
redevelopment efforts of the area around the university.
The Gallery building will provide 55,000 m2 of space
30
(nearly eight football fields) for laboratories, offices, manufacturing areas and exhibition halls. The
building’s unique location enables it to bridge the gap between science and industry.
The building, with its unique architecture and convenient location, will be transformed into a 300meter-long ‘showcase’ where scientists and businesses can raise the profile of their new
developments.
The building will be housing an incubator for start-ups in nano-, biomedical technology and the IT
sector. The Gallery is also available to R&D departments of large companies, high-end laboratories
and production facilities.
For more information on Kennispark: www.kennispark.nl
For more information on Business & Science Park:
www.sciencepark.nl and www.ovbsp.nl
31
Mercator Technology & Science Park
Mercator Technology & Science Park started as a public private
initiative in the nineties. Its primary aim was to create a meeting
place for scientists and companies. Mercator offers more than
only office space, it also offers links to the research fields of Radboud University Nijmegen, such as
cognition sciences, IC technology, bio-informatics, bio-medical research, molecular life sciences and
material research.
Mercator offers unique possibilities for a cross-fertilization between science & business. The University
Medical Centre St. Radboud is in walking distance and there is access to strong research centers for
language and speaking technology and neuroscience. It is also possible to use nearby laboratories
and research facilities such as the Nanolab and Innovationlab and to cooperate with research
institutes and science-based spin off companies.
Mercator is a dynamic centre where university talent and
innovative entrepreneurs are attracted to and interaction leads
to new products and services.
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

Short lease possibilities; “easy in – easy out”
Office space from 25 sqm up to several floors.
High-tech conference rooms.
For more information: www.mercatorsciencepark.nl (only in
Dutch)
32
Nanotechnology Companies in
East Netherlands
33
3T
3T BV is a leading independent solution provider in the market for customer-specific industrial
products and systems, based on microelectronics and software.3T's all-round team is specialized in
engineering solutions for complex applications. They use state-of-the-art microelectronics, embedded
software and systems, PC software, sensors and microsystem technology to translate your concept
into a tailor-made solution.
Sector
Location in (East) Netherlands
Activities in East Netherlands
Company size range
Country of origin
Technology
Enschede
R&D, production
20-49 (Provincie Overijssel, BIRO)
Netherlands
For more information: http://www.3t.nl
Aquamarijn Micro Filtration
Aquamarijn creates new technologies for filtration, (micro) analysis, cell detection, nanopatterning and
micro moulding using nano and micro engineering. Aquamarijn is specialized in MEMS
micromachining, polymeric micro moulding and fiber spinning techniques.Nano and Micro
Engineering- Aquamarijn introduces the microsieve a micro filtration membrane- Smart, portable and
inexpensive sensor templates
Sector
Company size range
Country of origin
Technology
Zutphen
R&D
2-4 (Provincie Gelderland, PWE)
Netherlands
For more information: http://www.aquamarijn.nl
34
AeroTech Development
AeroTech Development is an in January 2010 founded high-tech University of Twente
spin-off company, which specializes in the development and valorization of
nanocomposite polymers with a tunable porosity and pore sizes at the micrometer and
nanometer lengthscale through utilization of state of the art polymer engineering and
nano-technology. The developed porous nanocomposite materials have a great
potential for utilization in a wide varity of applications encountered in every day life.
In addition, AeroTech Development offers their expertise in 2D/3D surface modification
reactions, surface characterization and thermal analysis of polymers to customers with
specific needs in those areas.
Sector
Company size range
Country of origin
Technology
Heteren
development & valorization
1 (Oost NV)
Netherlands
For more information: http://www.atdnano.com/
Blue4Green
Blue4Green is a young, innovative company developing technology for better and faster methods to
diagnose ailments and diseases in animals. Blue4Green's technology enables veterinary
professionals to diagnose on the spot, allowing for precautionary measures and faster treatment of
sick animals.
The Lab-on-a-Chip technology was developed in an international effort spanning many years. In
2000, the Lab-on-a-chip Group at Twente University and the MESA+ Institute for nanotechnology
started a collaborative study into new methods to measure
lithium levels in blood samples. The study was successful and
showed that levels of other charged particles, such as calcium
and magnesium, can be measured as well.
More research is required to prepare the Lab-on-Chip
technology for production aimed at other applications.
Blue4Green therefore engages in intensive research efforts
with scientific partners around the globe.
Sector
Company size range
Country of origin
Technology
Enschede
R&D
2-4 (Oost NV)
Netherlands
For more information: http://www.blue4green.com
35
Bronkhorst High-Tech
Bronkhorst High-Tech B.V., established in 1981, offers the most extensive product range of thermal
mass flow meters and controllers on the market. Numerous styles of both
standard and bespoke instruments can be offered for applications in laboratory,
industrial and hazardous areas.The full scale measuring range (with 50:1 turndown) for these instruments can be selected between 0-1 mln/min and 0-10000
m3n/h for gases and 0-30 mg/h up to 0-20 kg/h for liquids. Furthermore
Bronkhorst High-Tech offers pressure transducers and controllers with a
minimum range of 0-100 mbar and a maximum range of 0-400 bar. Bronkhorst's
Coriolis Mass Flow Meters/Controllers for gases and liquids have a
measurement capability between 0,4...20 g/h and 6...600 kg/h. The most recent
development is a series of ultra-compact, chip-sensor based
Sector
Company size range
Country of origin
Technology
Ruurlo
R&D, Production, M&S
200-499 (Oost NV)
Netherlands
For more information: http://www.bronkhorst.com
Cameron Health
Cameron has developed a totally subcutaneous implantable
defibrillator (S-ICD) System that remedies many of the issues
associated with traditional implantable cardioverter defibrillators
(ICD’s). Specifically, Cameron's S-ICD System is designed to be
smarter, more capable, and less time-consuming to implant, program
and follow-up. An ICD is a small battery powered electrical pulse
generator that is implanted in patients who are at risk for ventricular
tachyarrhythmias. Cameron’s concept: Effortless Rhythm
Management.
Sector
Company size range
Country of origin
Health
Arnhem
Sales, distribution, wholesale
1 (Provincie Gelderland, PWE)
United States
For more information: http://www.cameronhealth.com
36
Dannalab
DANNALAB is an independent company offering a range of analytical services for
characterization of pharmaceuticals, polymers and other materials. Some of
Dannalab's services are related to intellectual property and patents. Dannalab's
business is based on novel characterization techniques combined with an expertise
in dedicated instrumentation. As well as the analytical services that the company
provides, it is involved in contract research targeting new analytical methods; in
both hardware and software. These projects are being conducted for one of the
major suppliers of analytical X-Ray instrumentation - PANalytical B.V. (formerly
Philips Analytical) - and results are implemented in the commercial
products.Dannalab's research partners include: - PANalytical B.V. - MESA+ Institute
of Nanotechnology
Sector
Company size range
Country of origin
Technology
Enschede
R&D
(Oost NV)
Netherlands
For more information: http://www.dannalab.com
Delta Mask
Delta Mask was founded in 1984 and has a wide experience in
mask making. The company started with producing photoemulsion masks, but nowadays only 4x4 and 5x5 inch chromium
masks are produced. Delta Mask cooperates closely with
WIEWEB a company that develops software for designing Sensor
and IC- layouts. Data formats which can be handled for mask
making are the CIF, GDSII and DXF.Delta Mask uses chrome
blanks, fabricated by Hoya, for mask making. Glass quality of the
plates is Soda Lime, to keep the price of a mask as low as
possible. Thickness of the chrome layer is 980 Å
Sector
Company size range
Country of origin
Technology
Enschede
Fabrication, Sales
2-4 (Oost NV)
Netherlands
For more information: http://www.deltamask.nl
37
Demcon
Demcon realizes high-tech mechatronic systems and products
through research, development and production. Demcon generates
high-end solutions for complex issues in various markets, ranging
from semicon and defense to medical and life sciences. Demcon
offers complete mechatronic solutions: mechanics, electronics,
software, optics/lasers, mechatronic system engineering, industrial
design, prototyping and production.
Sector
Company size range
Country of origin
Technology
Enschede
R&D, production, sales
Netherlands
For more information: http://www.demcon.nl
eMALDI
eMALDI is a novel patented technology that transforms the popular analytical detection method
MALDI-MS into a more sensitive, robust and faster method by solving a bottleneck in sample
preparation stage.
Sector
Company size range
Country of origin
Technology
Enschede
1 (Oost NV)
Netherlands
For more information: http://www.emaldi.eu
38
Encapson
Encapson is a dynamic, technology-driven company that specialises in the use of polymer-based
capsules for microencapsulation. Encapson can encapsulate a wide range of compounds, such as
enzymes, pharmaceuticals, catalysts and oils. The use of different building blocks allows Encapson to
prepare microcapsules with a variety of properties, such as biodegradability, porosity, size and
stability.
Next to continuously performing contract product development R&D, Encapson develops new
products using micro-encapsulation technology. Encapson developed two products Capsol and Sonocoat.
Sector
Company size range
Country of origin
Technology
Nijmegen
R&D
Netherlands
For more information: http://www.encapson.com
IBIS Technologies
IBIS Technologies is an analysis and instrumentation company for label free and in depth monitoring
of multiple biomolecular interactions using array technology. IBIS Technologies is developer and
supplier of biosensor based analytical instrumentation and consumables for the Life Science and R&D
markets. Focus is to provide users with high end instrumentation of uncompromised quality in
combination with lowest costs of ownership.
Sector
Company size range
Country of origin
Technology
Hengelo (O)
Netherlands
For more information: http://www.ibis-spr.nl
39
IMS
IMS delivers worldwide manufacturing solutions to customers in the high precision, electronics and
medical industry.
IMS is an experienced company in the field of manufacturing solutions for micro assembly challenges.
IMS provides micro assembly solutions to customers worldwide for more 10 years now.
As part of the WWINN group IMS has access to a broad network of partners.
Sector
Company size range
Country of origin
For more information: http://www.ims-nl.com
Technology
Almelo
Development, assembly, installation
Netherlands
Inertia
Using low-cost wireless sensor nodes, Inertia captures and monitors the motion of people and moving
objects, recognizes current situations and activities, provides constructive feedback and takes
appropriate actions.
The Inertia system is a collection of intelligent sensor nodes that build a wireless network. Using the
wireless medium as the communication channel, the system processes data collaboratively and
performs distributed monitoring and actuating tasks.
Unique to the Inertia system is that it can analyze the dynamics of the environment using only lowpower wireless sensor nodes.
Sector
Company size range
Country of origin
Technology
Enschede
R&D, M&S
2-4 (Oost NV)
Netherlands
For more information: http://www.inertia-technology.com
40
LioniX
LioniX is a leading provider in development and small to high volume production of leveraging and
innovative products based on microsystem technology and MEMS. Core technologies are integrated
optics and microfluidics. LioniX also provides MEMS foundry services. The combination of
microfluidics and integrated optics gives LioniX an unrivalled expertise in the emerging area of Labon-a-Chip, while the combination of integrated optics with the micromechanics expertise assures us a
strong position in the area of MOEMS (Micro-Electro-Optical Mechanical Systems).
Sector
Company size range
Country of origin
Technology
Enschede
Unknown
Netherlands
For more information: http://www.lionixbv.nl
MASER Engineering
MASER Engineering, founded in 1993, is an independent engineering service company operating in
the semiconductor and electronic systems industry.
Reliability Test and Diagnostic services are offered to a wide range of customers that are active as
Fabless Semiconductor or Integrated Device Manufacturers, automotive electronics supplier or in
Aerospace and Space applications.
Sector
Company size range
Country of origin
Technology
Enschede
Testing, Consulting, Engineering
Netherlands
For more information: http://www.maser.nl
41
Medimate
Medimate develops healthcare solutions for healthcare professionals,
patients, and researchers by using a unique, manageable measuring
instrument, the Medimate Multireader®. With this Multireader® and a
Disposable Chip, Medimate offers solutions for situations in which a
high added value is created by taking decentralized measurements or
self monitoring the concentrations in the blood level.
Sector
Company size range
Country of origin
Health
Enschede
5-9 (Oost NV)
Netherlands
For more information: http://www.medimate.nl
Medspray
Medspray develops and produces unique spray nozzles for near mono-disperse aerosol devices. All
devices and spray nozzle units are based on own proprietary technology. Inhalation therapy becomes
more effective and simple. Medspray develops the device and the manufacturing technology for the
next generation mono-disperse liquid based aerosol and spray devices. The devices generate
aerosols with pre-set (customized) particle size distributions. Technology is centered on design and
manufacturing of small atomizers using lithography based, wafer scale, micro machined nozzle
membranes. Focus is on simple but very efficient local or systemic delivery of drugs, targeted to
specific sites in the human body.
Sector
Company size range
Country of origin
Technology
Enschede
5-9 (Oost NV)
Netherlands
For more information: http://www.medspray.nl
42
MicroCreate
MicroCreate is an independent company providing MEMS foundry services, consultancy and
fabrication of microdevices for corporate and academic research laboratories who want to outsource
cleanroom processing and might not have access to critical equipment and technologies as provided
by the Mesa+ NanoLab at the University of Twente.
The company was founded in 2012 by ir. Kechun(Kees) Ma, working as
cleanroom freelancer (ZZPer), having more than 10 years experience in
MEMS fabrication at the Transducers Science and Technology (TST)
research group at the University of Twente, The Netherlands.
Sector
Company size range
Country of origin
Technology
Enschede
Consultancy, Fabrication
1 (Oost NV)
Netherlands
For more information: http://www.microcreate.nl
Microflown Technologies
Microflown Technologies develops and markets highly innovative products and (on site) testing
services in the field of noise and vibration.
Microflown Technologies develops and markets innovative (acoustic) testing techniques to the
aerospace, automotive and defence industry. Within the vehicle manufacturing industry, Microflown
based testing methods are used for both the development of new prototypes and end of line acoustic
testing during manufacturing
Sector
Company size range
Country of origin
Technology
Arnhem
R&D, Production, M&S
Netherlands
For more information: http://www.microflown.com
43
MicroNext
MicroNext is specialized in the development of technology for the production of micro and nano
texturized polymeric products. Polymeric micro molding is applied for large-volume production of
micro structured flat sheets and fibers for e.g. textile and polymeric filters.
MicroNext offers proactive support in research and development for successful implementation of
polymeric micro molding solutions.
Sector
Company size range
Country of origin
Technology
Zutphen
1 (Oost NV)
Netherlands
For more information: http://www.micronext.nl
Micronit
Micronit has been manufacturing glass-based lab-on-a-chip products for more than ten years. Micronit
has extensive experience in micromachining and microfluidics and is a key supplier
of microfluidic devices to life sciences and chemistry markets. Micronit is providing high quality lab-ona-chip components for analytical instrumentation and is also a dedicated research and development
partner for both science and industry.
Microfluidic glass chips are manufactured by etching or powderblasting holes, cavities, microchannels
and nanochannels in glass substrates. If required electrodes can be integrated in the devices. These
substrates are then bonded and diced to create the individual devices.
Sector
Company size range
Country of origin
Technology
Enschede
R&D, development, production, sales
Netherlands
For more information: http://www.micronit.com
44
Mosaic Systems
Mosaic Systems BV is a Dutch biotech-focussed company specializing in large scale biologics
separation and purification for Agri, Food Ingredients, and (Bio)Pharmaceuticals. Limiting factor
currently is through-put resulting in limited productivity [kg/hr]. Mosaic Systems has solved the
through-put limitations providing a 4 to more than 50 times higher productivity. Mosaic Systems
develops Mosaic Systems Module™ concepts to perform under a wide variety of process conditions,
based on your current chromatography medium, for high productivity, high resolution and low buffer
consumption. Through a patented mixed-matrix-membrane process Mosaic Systems manufactures
for a variety of process conditions: pre-filtered feeds, direct adsorption from fermentation broth,
combining filtration and chromatography. Proof-of-Technology has been shown with several
(multinational) customers in Food Ingredients, (Bio)Pharma and Dairy.
Sector
Company size range
Country of origin
Health
Enschede
R&D, production, service, sale
2-4 (Oost NV)
Netherlands
For more information: http://www.mosaicsystems.nl
MyLife Technologies
MyLife Technologies develops and fabricates ceramic micro needle arrays. The micro needles can
also be coated with a substance that needs to be delivered so it will dissolve into the skin. It is also
possible to make the needles electrically conductive and use them as electrodes for EEG
measurements.
MyLife Technologies continuously expands its knowledge on micro and nanofluidic transport both in
the patch and in the micro needles. MyLife Technologies can also supply research groups with micro
needle arrays or do contract research. MyLife Technologies' micro needle arrays provide a practical
and easy method for sampling and administering of substances relevant to the user.
Sector
Company size range
Country of origin
Technology
Enschede
R&D
Netherlands
For more information: http://www.mylifetechnologies.nl
45
Nanomi
Nanomi is a drug delivery company providing expertise and technology for the development and
manufacture of microsphere based injectable controlled release formulations. The company's
proprietary Monosphere Technology, that brings the precision of semiconductor technology to the
pharmaceutical field, provides unprecedented predictability, uniformity and scalability of the
microsphere manufacturing process from lab to fab.
Sector
Company size range
Country of origin
Health
Oldenzaal
R&D
1 (Oost NV)
Netherlands
For more information: http://www.nanomi.com
NanoPhysics
NanoPhysics B.V. is an independent analytical service lab providing integral analysis solutions for
many industries like semiconductor, automotive, pharmaceutical, renewable energy and
nanotechnology. They also serve research institutes, suppliers, universities and high tech companies.
The company was founded in 2011 by ir. Patrick Grunder and ing. Tim Velthof. They both studied
Applied Physics and have more than 15 year experience in the semiconductor industry. They both
encourage collaborative projects with both private and public research sectors. Due to their solid
network of complimentary partners and personal knowledge and care they are capable to offer their
customers an integral solution for complex cases and connect the right dots.
Sector
Company size range
Country of origin
Technology
Enschede
2-4 (Oost NV)
Netherlands
For more information: http://www.nanophysics.nl
46
Nanosens
Nanosens develops and utilizes the latest developments and advancements of the just emerging and
exciting nanotechnology to make smart, portable and inexpensive sensing systems for ultrasensitive
and rapid detection of biological and chemical species.
Nanosens works to bring innovative ideas and concepts from the sensor laboratories to the
application worlds (I2A). With focus on the sensor application areas that have a great impact on
society and on industry, such as:
Nanobio and chemical sensors for life sciences and health care (medical), security (warfare), and
water control
Nano gas sensors for the automotive, pollution control, safety and health.
Besides active R&D on nanosensor technology, Nanosens also will offer " Micro and Nano
Technology Foundry Services" (MEMS/NEMS) to customers.
Sector
Company size range
Country of origin
Health
Zutphen
R&D
Netherlands
For more information: http://www.nanosens.nl
NXP
NXP Semiconductors N.V. (Nasdaq: NXPI) provides High Performance Mixed Signal and Standard
Product solutions that leverage its leading RF, Analog, Power Management, Interface, Security and
Digital Processing expertise. These innovations are used in a wide range of automotive, identification,
wireless infrastructure, lighting, industrial, mobile, consumer and computing applications. A global
semiconductor company with operations in more than 30 countries.
Sector
Company size range
Country of origin
Technology
Nijmegen
R&D, Manufacturing, M&S
>1000 (Provincie Gelderland, PWE)
United States
For more information: http://www.nxp.com
47
Nymus 3D
Due to the broad skillset available in-house, animations can be delivered at a high technical and
visual level.
Scientific visualisation: animation, illustration and cover images
Architectural visualisation: from single buildings to big areas
Interactive Web Applications
Stereo3D presentations and setups
Sector
Company size range
Country of origin
Technology
Enschede
Design, Consultancy, Sales
2-4 (Oost NV)
Netherlands
For more information: http://www.nymus3d.nl
Optisense
Optisense develops highly sensitive biosensors for real-time monitoring of contaminants and
biochemical substances. The Optisense ‘Lab-on-Chip’ sensor is used for
real-time and on-site detection. Based on a unique combination of an
integrated optic chip, a biochemical transduction layer, micro-fluidics and
electronics, the Optisense patented ‘Lab-on-Chip’ sensor technology
guarantees high-end laboratory sensitivity (lower parts per billion range).
Sector
Company size range
Country of origin
Technology
Enschede
Research & Development
Netherlands
For more information: http://www.optisense.nl
48
Ostendum
Ostendum is a group of companies that focuses on the commercialization of optical detection
methods regarding the presence of micro-organisms, biomarkers, (bio-) molecules and (nano-)
particles. Ostendum develops and produces both the necessary hardware and software, including its
own lab-on-a-chip line. Ostendum’s technology platform classifies as nanotech as well as biotech and
Ostendum claims that its detection limit is at least 100 times more sensitive than currently available
competing detection methods.
Sector
Company size range
Country of origin
Technology
Enschede
R&D
Netherlands
For more information: http://www.ostendum.com
PANalytical
PANalytical is the world's leading supplier of analytical instrumentation and software for X-ray
diffraction (XRD) and X-ray fluorescence spectrometry (XRF), with more than half a century of
experience. The materials characterization equipment is used for scientific research and
development, for industrial process control applications and for semiconductor metrology. The product
portfolio includes a broad range of XRD and XRF systems and software widely used for the analysis
and materials characterization of products such as cement, metals and steel, nanomaterials, plastics,
polymers and petrochemicals, industrial minerals, glass, catalysts, semiconductors, thin films and
advanced materials, pharmaceutical solids, recycled materials and environmental samples.
PANalytical is part of Spectris plc, the precision instrumentation and controls company.
Sector
Company size range
Country of origin
Technology
Almelo
United Kingdom
For more information: http://www.panalytical.com
49
Pentair X-Flow (former Norit X-Flow)
Water...life depends on it. And although about 70 percent of the earth's surface is covered with water,
more than two billion people are deprived of a constant and reliable source of drinking water on a
daily basis. Worldwide, governments, municipalities and industries face the challenge of safeguarding
current and future drinking and process water requirements. These dire circumstances cannot be
tackled simply by doing more of the same; they require new visions and cutting-edge innovations.This
is why Pentair X-Flow, the world's leading ultrafiltration (UF) technology company for both small and
large scale systems, is constantly investing in research and development to increase the performance
and efficiency of a proven technology and pioneering new solutions for water purification.One of
Pentair X-Flow's answers to the world's water crisis is the advanced engineering upgrade to the Norit
AquaflexTM UF system. With a proven membrane technology at its core, the Norit AquaflexTM is the
best performing water treatment system at a considerably lower total cost of ownership. Addressing
the emerging legislation for turbidity and microbiology, the Norit AquaflexTM system provides superior
separation performance and effectively rejectsviruses and chlorine resistant organisms, such as
Cryptosporidium and Giardia.
Sector
Company size range
Country of origin
Technology
Enschede
production, sales, research and development
United States
For more information: http://www.x-flow.com/
PhoeniX software
PhoeniX enables companies and institutes worldwide with software solutions to design and
manufacture. PhoeniX is currently serving more than 150 customers worldwide, from SME's to large
multinationals, from private persons to major research institutes. Their activities are in many different
fields of the micro and nanotechnology landscape, like: - micro fluidics - BIO sensors - compound
semiconductors - MEMS & MOEMS - integrated optics & photonics - RF micro electronics - nano
materials research
Sector
Company size range
Country of origin
Technology
Enschede
R&D, production, sales, service
Netherlands
For more information: http://www.phoenixbv.com
50
Relitech
ReliTech, a merger of "ReliableTechnology", is a reliable partner (co-creator) for the development of
practical solutions in measurement techniques.
One of the products developed by ReliTech for Viasys Healthcare is the Oxycon Mobile, a portable
ergo-spirometry product. The system consists of:
SBx: Sensor Box (Measurement unit for volume and breathing gasses)
DEx: Data Exchange Unit (Data storage and communication module)
PCa: Powersupply en Calibration Unit
Host: PC to control the test and for on-line presentation of the measurement data
Sector
Company size range
Country of origin
Technology
Almelo
R&D, sales, service
Netherlands
For more information: http://www.relitech.nl
Satrax
SATRAX is working to introduce revolutionary antenna system which will provide users in ground
transportation, nautical, and avionics industries with high-speed flexible satellite broadband
communication. SATRAX develops system that meets future requirements for broadband
communications with an ultra flat "smart" antenna, capable of maintaining connection with satellites
even at high speeds.Smart Antenna Satcom Systems
Sector
Company size range
Country of origin
Technology
Enschede
R&D
1 (Oost NV)
Netherlands
For more information: http://www.satrax.nl
51
Sensata Technologies Holland
Sensata Technologies provides leaders in the global automotive, appliance, aircraft, industrial, and
HVAC markets with sensing and protection solutions. Sensata's European business and technology
development center is located in the Netherlands.
Sensata Technologies Holland B.V. offers a wide range of products including sensor, control, and
protection products.
Sector
Company size range
Country of origin
Technology
Almelo
R&D, production
United States
For more information: http://www.sensata.nl
Sentron Europe
Sentron is a high tech company that designs and produces high quality pH sensors and pressure
sensors:
ISFET pH sensors are very robust and small in size. This differentiates them from conventional glass
electrodes and other ISFET sensors which are fragile and / or larger in size. Sentron’s ISFET pH
sensors are the only ISFET pH sensors used in FDA approved medical devices
Pressure sensors are small yet highly accurate and are incorporated into a wide range of medical
devices
Sentron also provides design support and sub assembly services to OEM customers that integrate
these sensors into their products. In addition, Sentron offers its own line of high quality pH meters and
ISFET probes suitable for applications requiring robust glass-free and / or small pH measurement.
Sector
Company size range
Country of origin
Technology
Roden
Design, Production, Sales
10-19 (Oost NV)
Netherlands
For more information: http://www.sentron.nl
52
SenzAir
SenzAir focuses on the diagnostics of exhaled air.
The SenzAir technology enables the measurement or monitoring of the physical health of people in a
patient-friendly and non-invasive way in an early stage.
Sector
Company size range
Country of origin
Technology
Enschede
Research & Development
Netherlands
For more information: http://www.senzair.nl
SmartTip
SmartTip specializes in the design, production and packaging of dedicated special purpose SPM
probes. SmartTip provides corporate and academic research laboratories with "Smart" probes for any
SPM application requiring more than just a bare Silicon or Nitride probe. SmartTip has developed its
Smart Coating technologies for MFM probes.
Sector
Company size range
Country of origin
Technology
Enschede
Design, production and packaging
Unknown
Netherlands
For more information: http://www.smarttip.nl
53
SolMateS
SolMateS is a high-tech company, offering material science related services. They pioneered and
developed in 2007 a new coating process called Large Area Pulsed Laser Deposition and coat since
2008 polymer optics for the military market. SolMateS-Piezo is the latest using the novel process to
deposit PbZrTiOx (PZT) thin films. Customers are using the Piezoelectric thin films as their basic
building block for several MEMS applications such as: print-heads, micro-pumps, energy harvesters,
tilt-table mirrors, IR-sensors, high K capacitors and ultrasound transducers. With this production
solution thin films of PbZrTiOx (PZT) are currently produced and compatible with standard silicon
process technology.
Sector
Company size range
Country of origin
Technology
Enschede
R&D, Production
Netherlands
For more information: http://www.solmates.nl
Tide Microfluidics
Tide Microfluidics' novel platform technology allows for the creation of monodisperse microbubbles.
The platform shows a robust production method for microbubbles of highly controlled size with a
narrow size distribution. This unique platform enables the formation of monodisperse microbubbles
with size choice between 2 to 10 microns and a narrow size distribution.
Sector
Company size range
Country of origin
Technology
Enschede
2-4 (Oost NV)
Netherlands
For more information: http://www.tidemicrofluidics.nl/
54
Thales Nederland
Thales Nederland is the largest defence company in the Netherlands and world-famous for its naval
radars and electro-optic sensors and naval combat system. Thales Nederland is active in projects that
are pursued by foreign Thales entities for Dutch customers. In this manner, Thales has supplied KLM
(Royal Dutch Airlines) with simulators. Thales is also actively involved in the national introduction of
electronic payment systems for public transport. The so-called Smart Card will in time be the sole
ticket used in Dutch public transport.
Sector
Company size range
Country of origin
Technology
Hengelo (O)
R&D, Production, Logistic Services
France
For more information: http://www.thalesgroup.com
Twente Solid State Technology (TSST)
Twente Solid State Technology (TSST) is specialized in design and production of customized thin film
deposition equipment, specifically Pulsed Laser Deposition equipment for advanced studies. An
example is the use of Reflection High Energy Electron Diffraction (RHEED) under high-pressure
conditions, which gives real-time information about the surface morphology during depositions.
The company also produces ceramic thin films, and offers services for research in the field of ceramic
thin films, such as the surface treatment of ceramic substrates. TSST is able to provide these services
due to the strong cooperation with the MESA+ institute at the University of Twente.
Sector
Company size range
Country of origin
Technology
Enschede
Design & Production
Netherlands
For more information: http://www.tsst.nl
55
U-Needle
Silicon micro needles
U-Needle develops and produces micro needles employing its patented in-plane silicon etching
method.
These micro needles cause minimal stress and pain when vaccinating or administering drugs to
patients.
Atom Sharp
U-Needles are atom sharp and have a relatively short bevel to facilitate
shallow injections with high precision.
U-Needles are made of mono crystal high grade silicon, which is
biocompatible and shows no leachables.
Sector
Company size range
Country of origin
Technology
Enschede
2-4 (Oost NV)
Netherlands
For more information: http://www.uneedle.com
VDL Enabling Technologies Group
VDL Enabling Technologies Group is a tier-one contract manufacturing partner, delivering high tech
capital equipment to leading OEM companies and users of advanced production lines. Services
include prototyping, customer specific factory automation projects and series manufacturing of 'highmix low-volume' products. VDL operates from 6 manufacturing locations in Europe and Asia.
Sector
Company size range
Country of origin
Technology
Almelo
R&D, production
Netherlands
For more information: http://www.vdletg.com
56
WieWeb Software
WieWeb software is a small software company specialized in the development of technical, scientific
and mathematical software. Main product is the layout editor CleWin, a layout editor designed in
cooperation with MESA+ at the University of Twente and Deltamaks, a mask making company.
Sector
Company size range
Country of origin
Technology
Hengelo
Software design
Netherlands
For more information: http://www.wieweb.com
XiO Photonics
XiO Photonics exploits a photonics integration platform from the UV to IR that offers integrated optical
solutions for products ranging from telecom, datacom & sensing and visible light applications.
XiO Photonics supplies besides standard fiber optical products, like splitters and patchcords, also the
next generation optical modules that integrate advanced functionality on a compact optical chip. This
way the benefits of integration, known from the IC industry, can be used for photonic applications.
Sector
Company size range
Country of origin
Technology
Enschede
Netherlands
For more information: http://www.xiophotonics.com
57
Part 2: General Information East Netherlands
58
East Netherlands
East Netherlands is located strategically between two key European
economies: the Dutch Randstad (Amsterdam, Rotterdam, Utrecht) and
the German Ruhr Area (i.e. Düsseldorf, Cologne).
Schiphol Amsterdam Airport is within 60 - 90 minutes travel by car or
(direct) train
Like the rest of the country, East Netherlands has a highly educated,
multilingual and internationally oriented workforce.
East Netherlands is a focal point for medical life sciences and medical
devices.
There are strong science and business clusters around university and
medical centre in Nijmegen and Technical University Twente in
Enschede.
Some Figures
Population
Labor Force 2012
Land Surface 2008
GDP per head 2010
Top 3 Universities
3,148,413 (per 1-1-2012)
1,439,000
855,737 ha
Gelderland € 29.899
Overijssel € 31.389
Wageningen Universiteit: Agrifood
Universiteit Twente: Hightech Materials
Radboud Universiteit Nijmegen: Life Sciences & Health
source CBS Stattline
59
East Netherlands in Figures
Population (1-1-2013)
Land surface (km2) (2012)
Population density per km2
Labor force (age 15-65), 2012 x1,000
- primary education x1,000
- secondary education x1,000
- higher education x1,000
GDP (* million €), 2010
GDP per head (* 1,000 €), 2010
Number of jobs, December 2011
x1,000
Unemployment (%, 2012)
Netherlands
East Netherlands
Gelderland
Overijssel
16,779,575
33,718,28
496
10,992
3,344
4,432
3,108
300,434
35,616
3,155,141
8,294,01
374
2,038
631
856
533
26,023
30,644
2,015,791
4,969,52
405
1,304
408
536
348
33,104
29,899
1,139,350
3,324,49
342
734
223
320
185
18,942
31,389
7,904,6
6,4
1,446,2
6,5
914,3
5,7
531,9
6,4
Source: CBS/Statline, July 2013
Southwest
Gelderland
Arnhem/
Nijmegen
236,688
696,06
339
716,391
898,85
794
400,727
1,545,90
260
661,985
1,828,71
360
626,726
1,489,47
421
1525,818
416,38
367
3659,806
1,418,68
252
154
56
64
33
3,545
29,841
476
131
183
157
12,040
30,297
254
81
115
55
5,947
26,519
421
140
174
103
11,571
31,570
404
125
176
99
10,131
30,658
100
26
43
30
2,423
28,581
230
72
101
56
6,388
33,890
102,1
4,8
329,1
7
165,9
5
317,3
4,9
282,7
6,9
69,8
5,7
179,4
5,8
Population (1-1-2013)
Land surface (km2) (2012)
Population density per km2
Labor force (age 15-65),
2012, x 1,000
- primary education x1,000
- secondary education x1,000
- higher education x1,000
GDP (* million €), 2010
GDP per head (* 1,000 €),
2010
Number of jobs, December
2011
x1,000
Unemployment (%, 2012)
Achterhoek
Veluwe
Twente
Southwest
Overijssel
Major cities in East Netherlands
Apeldoorn
Arnhem
Ede
Enschede
Nijmegen
Zwolle
Population (2013)
157,315
149,827
109,823
158,627
166,382
122,562
60
North
Overijssel
Infrastructure in East Netherlands
The infrastructure in East Netherlands is well developed and offers excellent, direct access to national
and international road networks. Traffic density is relatively light and the region is well served by
international, national and local rail systems.
East Netherlands is one of the strategic hubs of Europe, centrally situated between important
economic centers such as the Randstad conurbations in the west of the Netherlands and the Ruhrarea in Germany. It is only a short distance from Amsterdam Airport (Schiphol), Port of Rotterdam,
Airport Münster-Osnabrück (FMO), Düsseldorf International and Airport Weeze. The arrival of the
Betuwe Route (freight rail) and the High Speed Line rail links in the east of the country ensures even
more efficient transportation.
Overland
Highway
A1
A2
A12
A15
A28
A30
A32
A35
A50
A73
From
Amsterdam
Amsterdam/Utrecht
The Hague
Rotterdam
Utrecht
A1
North-Netherlands
Almelo
Zwolle
Nijmegen
Miles
Amsterdam
Antwerp
Berlin
Dusseldorf
Hamburg
Copenhagen
London
Madrid
Milan
Munich
Paris
Prague
Rotterdam
The Hague
Warsaw
65
100
370
75
250
445
335
1,100
610
450
320
525
75
75
720
Via
Apeldoorn/Hengelo
Ede/Arnhem
Zwolle
Zwolle
Hengelo/Enschede
Apeldoorn
MILEAGE CHART
Arnhem
KM
Travelling
Time by Car
105
1h10
165
1h40
595
5h35
120
1h10
400
3h45
720
7h25
540
6h
1,775
16h45
980
9h15
725
6h40
515
4h50
850
7h35
120
1h15
120
1h15
1,160
12h35
To
Germany
South-Netherlands, Belgium
Germany
Arnhem/Nijmegen
North-Netherlands
Ede
Middle-Netherlands
Germany
Arnhem
South-Netherlands/Germany
Miles
Enschede
KM
100
160
315
85
195
400
400
1,160
615
460
375
450
125
125
665
160
260
510
135
315
640
640
1,870
990
740
610
730
200
200
1,075
Travelling
Time by Car
1h40
2h30
4h55
1h20
3h
6h45
6h55
17h30
9h25
6h45
5h45
7h05
1h60
1h60
11h55
Source: Google Maps
61
Railroads
National lines
From every large city in East Netherlands one can travel westwards directly to Amsterdam, Utrecht
and Rotterdam on efficient “InterCity” rail lines. These trains connect more than 30 cities in the
Netherlands. For longer distances InterCity lines are ideal because of their speed and comfort. The
trains appear in the vast majority of stations along designated routes every 30 minutes. In addition to
the InterCity trains there are many “stop-trains” which cater to the smaller stations along the routes.
International lines
Several international lines cross East Netherlands. From the cities Arnhem and Nijmegen international
railroads crosses the border with Germany. This means direct connections to the Ruhr-area and
further to southern and eastern Europe.
In addition a major west-east international line comes from the western parts of the Netherlands and
runs via the cities of Apeldoorn, Almelo and Oldenzaal to Germany (Hannover and Berlin). This
railroad connects East Netherlands with Germany, Scandinavia and Eastern Europe.
High Speed Line / ICE
The High Speed Line (HST) train is
bound to become a major
instrument for traveling throughout
Europe this century. TGV,
Eurostar, Thalys and ICE bring
nations and cities together, within a
few hours traveling. This train
stops at the city of Arnhem, while
the intercity trains stop in Hengelo.
Travel times to f.e. Frankfurt is only
2:30 hour and Amsterdam 1:10
hour. This will ensure even better
connection to main European
economic centers.
Freight train “Betuwe-route”
In the beginning of 2008 the
Betuwe Route started operating.
High Speed Line
This technological advanced track
the Port of Rotterdam to the German Ruhr-area and the rest of Eastern Europe. Not just the carriers
and shipping companies, but also a large part of the Dutch economy benefit from the ability to
transport goods straight off and without stopping from the coast to the German border and further on
into Europe. The competitive position of Rotterdam and the Netherlands as a shipping and distribution
country will be unquestionable strengthened.
Plans to develop a rail terminal in the middle of the Arnhem Nijmegen area, are well underway. This
terminal creates a direct rail link between the Arnhem Nijmegen area and Eastern Europe. It is evident
that the already highly valued logistical attractiveness of this area will improve even further.
62
Air transportation
Amsterdam Airport Schiphol
Amsterdam Airport Schiphol is a one to two hour drive from East Netherlands. 49.8 million passengers
pass through the gates of this airport in 2011 and more than 1.5 million tons of freight is transported.
Schiphol offers the professional services of a world-class air hub together with seamless linking with
the rest of Europe through outstandingly managed transport links.
Düsseldorf International
Düsseldorf International, is located on 115 km (72 miles) from Nijmegen. Regularly Düsseldorf
International is rated as the number one airport in Germany. From Düsseldorf one can travel to 59
countries with 180 destinations. In 2011 more than 20 million passengers passed the gates of this
airport. Düsseldorf International is the third largest airport in Germany.
Airport Weeze
Airport Weeze (less than 50 km (31 miles) from Nijmegen) commenced operations in May 2003 with
regularly scheduled airline services. Situated on highway A57 near Kleve, this airport has been
designed for low-cost airlines to operate efficiently in a modern and attractive environment. Airport
Weeze is easily accessible and is an inexpensive alternative for approximately 11 million Dutch and
German business travellers and tourists alike. The number of passengers in 2011 has risen to 2.4
million.
Airport Münster-Osnabrück
Airport Münster-Osnabrück (Germany, 70 km (44 miles) from Enschede), offers direct air connections
to Berlin, Dresden, Frankfurt, Leipzig, Munich, Nürnberg, Stuttgart, London, Paris, Prague and Zurich.
There are also charter flights to several foreign destinations. The number of passengers in 2009 has
exceeded almost 1.4 million.
Enschede Airport Twente
Enschede Airport Twente is located between the three most important cities in Twente, a region in the
east of the Netherlands: Enschede, Hengelo and Oldenzaal. It is designed to serve the three primary
interests of these three cities, respectively: Enschede and Hengelo for passenger traffic; Oldenzaal
and Hengelo for air freight and logistics. Enschede Airport Twente is like-rated with Amsterdam Airport
Schiphol, which allows lower tariffs, but without the delay of severe traffic congestion that is found at
Schiphol.
The Area Development Twente (ADT) is working to convert Enschede Airport Twente's current military
designation to full commercial civil aviation. This process should be complete by the end of 2014, and
the airport is expected to be fully operational for all types of traffic at that time.
Waterways
The Netherlands has had a longstanding history of carrying international trade over water. Even inland
you currently see a strong reliance on water transport. The rivers Waal, Rhine and Lek cross East
Netherlands. These rivers are being used by inland shipping for carrying freight from the Port of
Rotterdam to the German Ruhr-area and back.
The Twente Canal (up to 2,000 tons), with a tributary to Almelo, links Hengelo/Enschede with the
IJssel River. The IJssel River is the connection between the Rhine and the IJssel Lake (formerly the
Zuider Zee). Serviceable ports, such as Kampen, Zwolle and Deventer, are located on the IJssel
Lake's southern shore. The nearest major ports are Rotterdam and Amsterdam. Rotterdam, being the
world’s largest port, can be an ideal gateway to receiving goods coming from all over the world.
63
Distances (km)
East Netherlands: number of people within
Radius of 500 km
> 120 million people
Radius of 1,000 km
> 325 million people
Source: Oost NV, 2012
64
Economic Structure East-Netherlands
Number of Personnel in East-Netherlands, 1-1-2012
Netherlands
East-Netherlands
Agriculture
220,620
51,240
Industry
812,310
184,340
Public utilities
69,610
14,120
Construction
475,480
101,640
Trade
1,423,020
272,620
Transport & Storage
414,520
65,750
Hotel & Catering
352,530
65,770
Information & Communication
261,410
34,100
Financial services
232,710
29,020
Business services
1,174,300
199,290
Public
434,630
78,010
Education
543,200
105,980
Health care
1,311,700
271,670
Other
358,730
59,850
Total
8,084,740
1,533,420
Gelderland
28,990
109,970
9,940
62,130
170,300
42,630
42,130
24,050
20,350
135,780
51,660
67,140
182,990
41,460
989,540
Overijssel
22,250
74,370
4,180
39,510
102,320
23,120
23,640
10,050
8,670
63,510
26,350
38,840
88,680
18,390
543,880
Number of Personnel per region in East-Netherlands, 1-1-2012
Agriculture
Industry
Public utilities
Construction
Trade
Transport & Storage
Hotel & Catering
Information & Communication
Financial services
Business services
Public
Education
Health care
Other
Total
Achterhoek
Arnhem/
Nijmegen
North
Overijssel
Twente
Veluwe
SW
Gelderland
SW
Overijssel
9,710
30,380
1,290
12,800
33,990
7,350
8,610
3,040
2,050
16,440
5,510
11,200
34,410
6,750
183,520
4,430
31,780
5,640
15,760
54,460
13,900
15,350
8,460
7,490
55,400
19,420
28,410
76,560
15,420
352,460
8,870
20,910
2,250
13,560
31,600
10,220
8,020
3,470
3,720
20,470
11,340
13,860
28,780
6,230
183,290
9,570
43,710
1,450
21,990
58,320
10,700
12,670
4,760
4,120
33,450
12,700
20,650
45,960
9,710
289,770
8,670
35,120
2,180
24,560
59,530
12,680
14,320
9,130
9,690
47,430
24,230
22,010
59,270
14,620
343,430
6,180
12,690
830
9,010
22,320
8,700
3,860
3,430
1,130
16,510
2,510
5,530
12,760
4,680
110,130
3,810
9,760
480
3,970
12,400
2,190
2,960
1,820
830
9,590
2,310
4,320
13,950
2,450
70,830
Source: Lisa, July 2013
65
Office and manufacturing rents in the Netherlands
Office Rents 2012 (€ per m2)
450
400
400
350
300
250
220
175
200
150
100
130
70
130
70
125
135
90
80
60
135
185
210
175
140
85
90
90
85
80
90
85
50
Amsterdam
Utrecht
Den Haag
Zwolle
Arnhem
Nijmegen
Apeldoorn
Ede
Enschede
Hengelo
Deventer
Almelo
0
Manufacture rents 2012 (€ per m2)
80
70
65
70
65
70
65
60
55
60
55
50
55
50
45
50
37
40
30
30
25
25
30
25
30
25
25
30
30
25
20
10
Amsterdam
Utrecht
Den Haag
Zwolle
Arnhem
Nijmegen
Apeldoorn
Ede
Enschede
Hengelo
Deventer
Almelo
0
Source: DTZ Zadelhoff, January 2012
66
Number of Students and Graduates in East Netherlands
Number of Students per Study, 2010
Secondary
School
Netherlands
Overijssel
Gelderland
North Overijssel
South West Overijssel
Twente
Veluwe
Achterhoek
Arnhem/Nijmegen
South West Gelderland
Total
939,629
65,844
118,219
21,054
8,731
36,059
39,605
24,102
39,612
14,900
1,307,755
Professional
School
Vocational
Professional
School
Apprenticeship
Higher
Professional
Education
Scientific
Education
358,184
28,442
43,712
9,588
3,702
15,152
14,256
9,262
15,459
4,735
502,492
172,174
12,472
21,896
3,735
1,543
7,194
7,418
4,250
7,104
3,214
240,910
416,934
30,186
45,902
10,089
3,876
16,221
13,971
7,031
20,774
4,126
569,110
241,686
10,297
25,260
1,463
702
8,132
7,904
1,208
15,004
1,144
312,800
Number of Graduates per Study, 2009
Secondary
Professional
School
School
MBO
Netherlands
168,369
197,407
Overijssel
12,236
16,172
Gelderland
21,640
24,760
North Overijssel
4,006
5,168
South West Overijssel
1,596
2,025
Twente
6,634
8,979
Veluwe
7,139
8,138
Achterhoek
4,596
5,512
Arnhem/Nijmegen
7,076
7,997
South West Gelderland
2,829
3,113
Total
236,121
279,271
Bachelors
HBO/WO
Masters
WO
62,054
4,664
6,757
1,548
653
2,463
2,114
935
3,220
488
84,896
30,197
1,154
3,264
201
95
858
1,085
162
1,909
108
39,033
Source: CBS/Stattline, November 2012
67
Unemployment
A large pool of labor, also with relatively high education, is available.
Unemployed per 1.1.2013
Education Level
Netherlands
Grade School
VMBO Lower Vocational
HAVO/VWO
Higher Vocational
MBO General
Higher Vocational
HBO Bachelor
Professional Vocational
WO
Master University
148,523
105,012
East
Netherlands
26,582
19,852
Province of
Gelderland
16,456
12,294
Province of
Overijssel
10,126
7,558
23,495
3,666
2,359
1,307
52,205
9,304
5,663
3,641
72,831
13,171
8,126
5,045
29,657
4,567
3,269
1,298
UWV - regions
Unemployed per 1.1.2013 per Region
Education Level Achterhoek
Food Valley
(incl. Utrecht)
1,783
1,766
Grade School
VMBO Lower
1,809
1,263
vocational
HAVO/VWO
Higher vocational
202
276
MBO General
993
641
Higher vocational
HBO bachelor
Professional
1,177
896
vocational
WO master
243
425
University
Unemployed per 1.1.2013 per Region
Education Level Twente
Stedendriehoek
(incl. Flevoland)
7,022
4,740
Grade School
VMBO Lower
4,835
3,370
vocational
HAVO/VWO
789
679
Higher vocational
MBO General
2,202
1,644
Higher vocational
HBO bachelor
Professional
2,770
2,429
vocational
WO master
University
718
715
Midden
Gelderland
4,084
Rivierenland
1,697
Zuid Gelderland
(incl. Limburg)
3,714
2,874
1,326
2,465
610
199
614
1,267
2,076
569
968
683
1,589
259
1,162
707
IJsselvecht
(incl. Drente)
2,495
2,367
328
1,299
1,782
396
Source: www.werk.nl/werkgevers
68
Labor cost in East-Netherlands
The cost of labor in the east of the Netherlands is significantly lower than the average of the
Netherlands. This is partly attributable to the lower cost of living. This lower cost exists even among
wage grades that are governed by Collective Labor Agreements (CLA).
Wages, 2009
The Netherlands
East Netherlands
Gelderland
Overijssel
North Overijssel
Southwest Overijssel
Twente
Veluwe
Achterhoek
Arnhem-Nijmegen
Southwest Gelderland
Number of jobs
(* 1.000)
7.812
1.425
520
906
174
68
279
314
162
330
100
Wages
(* € Millionen)
298.517
51.435
18.314
33.121
6.202
2.272
9.840
11.474
5.966
12.105
3.576
Wage per job
(€)
38.213
36.095
35.219
36.557
35.644
33.412
35.269
36.541
36.827
36.682
35.760
Source: CBS/Statline, November 2012, Oost NV
Wage per job, 2009
39.000
38.000
37.000
35.000
34.000
33.000
32.000
Soutwest
Gelderland
ArnhemNijmegen
Achterhoek
Veluwe
Twente
Southwest
Overijssel
North
Overijssel
Overijssel
Gelderland
East
Netherlands
31.000
The
Netherlands
€
36.000
69
East Netherlands Development Agency
Strengthening and stimulating the economy of the provinces of Gelderland and Overijssel. In short,
this is the mission of the East Netherlands Development Agency (Oost NV).
Oost NV plays an important role in executing the economic policies of the Dutch government and the
Provinces of Gelderland and Overijssel and its various city governments. To achieve this it is
necessary to encourage a close cooperation between businesses, regional institutes, knowledge
institutes, and intermediaries. Oost NV acts as a bridge between government, companies and
knowledge institutes.
Oost NV helps entrepreneurs to innovate, invest and internationalize:


Supports organizations in expanding their businesses to the east of the Netherlands
Gives a boost to international companies, start-ups and growing SMEs
The activities of these four divisions of Oost NV are as follows:
Innovate
Regional Development & Innovations both initiates and stimulates activities that lead to a better
production and business climate for entrepreneurs. One example is the establishing of knowledge and
innovation clusters where businesses and knowledge institutes can interact. Another is the setting up
of sector-oriented knowledge centers and activities focused on strengthening a company’s knowledge
sharing infrastructure. The role of Development and Innovation is namely one of a process manager
who, through intensive guidance and coaching, helps guide projects to reality.
(Business) Infrastructure
This new branch will coordinate infrastructure renewal projects in existing industrial parks, which are
designed improve the quality of doing business. It will also work to develop new business and
knowledge parks as well as establishing and developing collective business centers.
International
Business Development works to attract new businesses and/or new business activities. It supports the
businesses of the provinces of Gelderland and Overijssel by supporting expansion activities and
setting up cooperative networks.
Invest
The Participation Company East Netherlands NV (PPM Oost) takes part in capital investments in
companies in the provinces of Gelderland and Overijssel. The company will take part in the
opportunity rich businesses environment that exists in the east of the Netherlands. Especially
interesting for PPM Oost NV are the high-tech and mature companies as well as infrastructure
creating activities.
Oost NV exists since June, 2003 and is a result of a merger of the former OOM (Regional
Development Agency for Overijssel) and GOM (Regional Development Agency for Gelderland).
Website: www.oostnv.com
70

East Netherlands - Oost NV | East Netherlands Development Agency

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