Kingdom of Saudi Arabia

Transcription

‫المملكة العربية السعودية‬
‫جامعة الملك فيصل‬
King Faisal University
‫كلية الصيدلة اإلكلينيكية‬
College of Clinical Pharmacy
0
Table of Contents
Pharmacy Orientation ........................................................................................ 3
Fundamentals of Pharmaceutics ....................................................................... 11
Pharmaceutical Organic Chemistry I ................................................................. 23
Physiology-1 ..................................................................................................... 34
Anatomy and Histology- I ................................................................................. 39
Biochemistry-1 ................................................................................................. 47
1
2
Ministry of Higher Education
DEPARTMENT OF Pharmacy Practice
Course Plan
A: General Information
Course Coordinator/Instructor: Dr Noor Kamil
Instructors: ---
Contacts:
1. Office No. 5895448
2. Office hours: 7:30-2:30
3. Email and office contacts: [email protected]
College/Department: Clinical Pharmacy/Pharmacy Practice
Course title and code: Pharmacy Orientation / 2030111
Year and Semester 1st Year 1st Level
Credit hours: 2
Pre-requisite --Schedule: Male: Lecture:
Female: Lecture:
Sunday
Monday
8:30 to 10:20, Practical: --11:30 to 1:35 Practical: ---
B: Course Description & Objectives
3
1.
Aims of the Course:
This course will cover The definition of Pharmacy and different areas of pharmacy profession and
history of pharmacy, Introduction to ancient drugs, Ancient Egyptian, Greek and Roman medicine,
Chinese and Indian medicine, Arab medicine in Spain and modern European medicine, History and
Global progress in Pharmaceutical education, Type of Different dosage forms, Methods for the
preparation of drugs, Introduction to Pharmacopoeias, formularies, regulatory control, and drug
management, Medical and pharmacy terminology related to body systems needed for complete
understanding of other courses, Role of clinical pharmacist in Community and Health care setting,
Introduction to clinical pharmacy and Role of clinical pharmacist In direct patient care, Objectives,
scope and requirements of Pharm.D. program, Introduction to various courses, compulsory and electives
included in Pharm.D. Program, Mode of teaching, learning and training in Pharm.D. program. i.e.
Problem Based Learning, Objective Structured Clinical Exam (OSCE), Institutional Pharmacy Training
and Experiential learning, College disciplinary rules and regulation for the examination.
2. Briefly describe any course development objectives that are being implemented. (eg increased use
of IT or web based reference material, changes in content as a result of new research in the field or
feedback from peers and students)
--3. Course Objectives:
After successful completion of the course, the student will be able to:
A. Describe the history of pharmacy, pharmacy profession and pharmacy education.
B. Describe objectives, scope and requirement of Pharm.D. Program and role of pharmacist in health
care system, in present and past.
C. Describe the medical terms in medical writings
D. Derive the meaning of medical words through analysis of prefixes, roots and suffixes.
E. Use medical terms to communicate effectively with other health care professionals
Topics to be covered till Mid Term
B: Learning Resources
1.
Required Textbook(s) :
1. Pharmacy: An Introduction to the Profession, L. Michael Posey, Publisher; American
Pharmacists Association, Ed. 2nd 2008.
2. Medical terminology. An Illustrated Guide, Barbra Cohen, Publisher; Lippincott , Ed. 7th
2013.
2. Additional References :
1. Pharmacy, What It is and How It Works, Kelly. Publisher; CRC Press; Ed. 2 nd 2006.
2. Opportunties in Pharmacy Careers, Fred Gable, Publisher; McGraw-Hill, Ed. 1st 2003.
3. Making Medicines, Brief History Of Pharmacy And Pharmaceuticals, Stuart Anderson,
Publisher; Pharmaceutical Press, Ed. 1st 2005.
4. Medical Terminology: A Short Course, Davi-Ellen Chabner BA MAT, Publisher: Saunders; Ed.
5th 2008.
5. Medical Terminology: A Living Language, Bonnie Fremgen, Suzanne S. Frucht, Publisher;
Prentice Hall, Ed. 4th 2008.
3.Electronic Materials, Web Sites, etc.
 www.emedicine.com
 www.sciencedirect.com
 www.pubmed.com
5- Other learning material such as computer-based programs/CD, professional
standards/regulations:
 British Pharmacopeia (B.P.)
 United States Pharmacopeia (U.S.P).
 British Pharmaceutical Codex (B.P.C).
 Martindale (extra pharmacopeia).
4
C: Course Weekly Activities
Week
Lectu
re
W-1
Sept 1
L1
Course Introduction
L2
Scope of Pharmacy & Strategy
of Course
L3
Pharmacy EducationObjectives of Pharma D
program
L4
- new curriculum
-college departments
- introduction to different
courses
- compulsory and elective
courses
Pharmacy career
W-2
Sept 8
W-3
Sept 15
W-4
Sept 22
W-5
Sept 29
L5
Topic (chapter/section)
L6
Role of pharmacist in self-care
and self-medication
L7
Pharmaceutical organizations
L8
(national & international)
L9
Information resources in
pharmacy
Intended Learning Outcomes
1.
2.
3.
4.
5.
6.
1.
2.
3.
4.
5.
Explain the college vision and mission.
Know about the Pharmacy orientation course
Learn the course description and its contents.
Know about the text and recommended books.
Detailed course schedule
Learn about the Pharm D program outcomes.
Define pharmacy and clinical pharmacy.
Define drug and medicine and its various forms.
Classify the drug.
Differentiate the drug with device.
Explain the different name and components of
the drugs.
1. College curriculum
2. Program credit hours distribution
3. College and university requirements
4. Distribution of different courses
5. Different departments of college
Same as above
1.
Recognized the diversity of pharmacy
profession
2. Different carrier pathways
3. Carrier opportunities in different fields
1. The role of pharmacist in community pharmacy
2. Define self care and self medication
3. Explain the principles of self care and self
medication
4. Describe the importance of self care and self
medication
1. Enlist the most common national and
international pharmaceutical organizations and
their roles and responsibitlies.
2. Define the working of pharmacist with national
& international organizations
3. Explain the how the pharmacist can promote
good
pharmaceutical practice by different
organizations
Same as above
1.
2.
3.
Define the sources of information in pharmacy
Explain the importance of the different sources
of information in pharmacy practice
Differentiate the primary, secondary, tertiary
and other specialized sources of information
5
Assignment/
projects
W-6
L10
(Pharmacopeias, formularies,
etc)
L11
Rational drug use
L12
History of Pharmacy
Oct 6-9)
(4 days)
Same as above
1. Define the rational use of drugs
2. Enlist the factors which lead to realize the
importance of RDU
3. Explain the reasons for irrational use of drugs
4. Describe the Steps to improve rational drug
prescribing
5. Discuss the demands of rational drug
use
1. Describe the history of pharmacy
2. Describe the ancient Egyptian history
3. Describe the Babylonian Indian and Chinese
medicines
4. Discuss the Greek and roman history of
pharmacy
W-7
Oct 13
W-8
Oct-20
(1 day)
W-8
Oct 21
(4 days)
L14
Pharmacy and medical
terminology
W-9
Oct 27
L15
-Basic word structure and
pronunciation
-Prefixes, suffixes ,word
roots and combining forms.
Basic word structure and
pronunciation
-Prefixes, suffixes ,word
roots and combining forms.
Descriptive prefixes, Prefixes
pertaining to colour,
positions, directions and
time.
Descriptive prefixes, Prefixes
pertaining to colour,
positions, directions and
time.
L16
W-10
Nov 3
L17
L18
W-11
Nov 10
L19
Cells, Tissues, and Organs
1.
2.
3.
Explain the purpose of medical terminology.
Define the terms root, suffix, and prefix.
Explain what combining forms are and why
they are used.
4. Name the languages from which most medical
word parts are derived.
5. Pronounce words according to the
pronunciation guide.
6. Analyze a case study with regard to some
concepts of medical terminology.
Same as above
Same as above
1. Define a suffix.
2. Give examples of how suffixes are used.
3. Recognize and use some general noun, adjective,
and plural suffixes used in medical terminology.
1. Define a prefix and explain how prefixes are used.
2. Identify and define some of the prefixes used in
medical terminology.
3. Use prefixes to form words used in medical
terminology.
1. Define basic terms pertaining to the structure and
function of body tissues.
2. Recognize and use roots and suffixes pertaining to
cells, tissues, and organs.
6
W-12
Nov 17
W-13
Nov 24
W-14
Dec 1
W-15
Dec 15
L20
Body Structure
L21
Diagnosis and Treatment
L22
Disease CVS
L23
Disease Respiratory
L24
Disease GI
L25
Disease Nervous System
L26
Disease Reproductive Male
L27
Disease Reproductive Female
1. Describe division of the body along three
different planes.
2. Locate the dorsal and ventral body cavities.
3. Locate the nine divisions of the abdomen.
4. Locate the four quadrants of the abdomen.
5. Describe the main body positions used in medical
practice.
6. Define basic terms describing body structure.
7. Recognize and use roots pertaining to body
regions.
8. Recognize and use prefixes pertaining to position
and direction.
1. List the major categories of diseases.
2. Define and give examples of neoplasia.
3. Identify and use word parts pertaining to
diseases.
4. Define the major terms describing types of
diseases.
5. List and define the major manifestations of
diseases
1. List the major categories of CVS diseases.
2. Identify and use word parts pertaining to CVS
diseases.
3. Define the major terms describing types of CVS
diseases.
4. List and define the major manifestations of CVS
diseases
1. List the major categories of CVS diseases.
2. Identify and use word parts pertaining to CVS
diseases.
3. Define the major terms describing types of CVS
diseases.
List and define the major manifestations of CVS
diseases
1. List the major categories of GI diseases.
2. Identify and use word parts pertaining to GI
diseases.
3. Define the major terms describing types of GI
diseases.
4. List and define the major manifestations of GI
diseases
1. List the major categories of CNS diseases.
2. Identify and use word parts pertaining to CNS
diseases.
3. Define the major terms describing types of CNS
diseases.
4. List and define the major manifestations of CNS
diseases
1. List the major categories of male reproductive
diseases.
2. Identify and use word parts pertaining to male
reproductive diseases
1. List the major categories of female reproductive
diseases.
2. Identify and use word parts pertaining to female
7
reproductive diseases.
L28
Drugs Name
W-16
Dec 22
L29
L30
Drugs
Drugs
W-17
Dec-29
L31
Revision
Revision
1. List some potential adverse effects of drugs.
2. Identify and use word parts pertaining to
drugs.
3. Recognize the major categories of drugs and
how they act.
4. List common routes for drug administration.
5. List standard forms in which liquid and solid
drugs are prepared.
6. Define abbreviations related to drugs and their
use
Same as above
Same as above
D. Class Format:
Class will consist of lectures and in some instances class discussion of problems or other assignments. In
addition, student will be responsible for all material in reading assignments regardless of whether or not the
material is discussed in class. Since these reading assignments are provided before class, it is expected that
students will read assignments before coming to class. It should be anticipated that class discussion may
require knowledge of the reading material and student who are not prepared may find class discussion
difficult to follow.
E. Library Assignments



Definition of Pharmacy
History of Pharmacy
Resources of Pharmacy
F. Service learning/Interprofessional Education:(if applicable)
E. Examinations and Assessment:
During the semester, there will be announced classroom quizzes in advance. These quizzes include topics from
the lectures that are covered before the quiz. The quizzes worth 10% of the final grade in the course.
For the theoretical section of this course, there will be 2 examinations, Midterm , and Final exam. The
outcome of these exams will represent 65% of the final grade in the course.
Overall, the course will be graded as follows: Schedules for Midterm and Final exams will be announced by the
Committee for Academic affairs in consultation with relevant students’ committee
8
Grading Scheme
Asses Assessment task (eg. essay, test, group project, examination
sment etc.)
1
2
5
6
7
9
Week due
Proportion
of Final
Assessment
Quiz #1
3rd
5%
Quiz #2
11th
5%
Class activities
6th
5%
Library/Home Assignment
12th
5%
Mid Term Exam
8th
30 %
End of
semester
50 %
Final Exam
Total
100%
F. Attendance:
I expect you to be at every class. I often give information in class that is not found in the textbook. Attendance
is one of the most important work ethics in this profession. If you miss 25% of the total classes during the
semester, you will be dropped from the final exam.
COMING IN LATE
While it is mandatory to come on time in every class, I do realize that some logical circumstances may prevent
you from getting to class on time. Please show respect if you come in late.
G. Academic Dishonesty and misconduct:
It includes all of the following:
1. Cheating in exams, quizzes, lab/small group sessions, from any source, like
fellow student, notes, electronic sources.
2. Plagiarism: presenting work, words, ideas, presentations, assignments of others, in
whole or in part, in assignments, presentations or projects
3. Falsifying tempering records of attendance, false excuses for absence
4. Disrespect to instructors, administration and colleagues
5. Non adherence to instructions regarding class discipline, dress code etc,
Students found to commit any of the above will be subject to disciplinary actions according to University Rules
and Regulations, mentioned in COCP Students’ Handbook
9
10
DEPARTMENT OF…………….
Course Plan
Course Coordinator/Instructor: Dr Seeharsha/ Dr Arshia Shariff
Instructors: Dr Sreeharsha and Dr Arshia Shariff
Contacts:
4. Office No. 1004
5. Office hours:
6. Email and office contacts: [email protected] and 035899912 – Dr. Harsha
[email protected] and 035899825 – Dr. Arshia
College/Department: College of Clinical Pharmacy/Department of Pharmaceutical Sciences
Course title and code: Fundamentals of Pharmaceutics , PS-1
st
st
Year and Semester: I yr, I semester
Credit hours: 2+1
Pre-requisite: none
Schedule:
Male: Lecture -Thursday: 7. 30 am – 9. 30 am – Theory,
Practical: Thursday: 10. 30am – 12.30pm
Female: Lecture: Sunday – 7.30 am to 8. 30 am and Wednesday - 7.30 am to 8. 30 am
Practical - : Monday 9. 30 - 11.30 (Section-1) and
Thursday 10. 30 am to 12.30pm (Section-2)
11
1. Aims of the Course
The main aim of the course is to give students currently working or intending to work in
hospital pharmacy and pharmaceutical industry an understanding of the fundamentals of
pharmaceutical technology relevant to product formulation, development and production. In
addition to theoretical knowledge, graduates are equipped with practical experience and
research methodology that enables them to become involved in research and development in
these areas..
2. Briefly describe any course development objectives that are being implemented. (eg increased use
of IT or web based reference material, changes in content as a result of new research in the field or

Students are being encouraged to update their knowledge by regular referencing on the
Saudi FDA /USFDA website through web.

Students will be given home assignments to encourage review of course related literature.

Case studies will be presented to train students so as to gain expertise in labeling and
reviewing prescriptions.
3. Course Objectives:
A. A Describe the art, science, and the correct procedures for the compounding extemporaneous
preparation.
B. Define, analyze, and overcome any pharmaceutical incompatibilities.
C. Explain parts of prescription and labeling requirements of the various products and controlled
substances
Topics to be covered till Mid Term :Prescription, controlled substances, Labelling Incompatibilities
1. Required Textbook(s) : Aulton's Pharmaceutics: The Design and Manufacture of Medicines by
rd
Michael.E Aulton, 3 edition.Churchill livingstone Elsevier publications. ISBN-13: 9780443101083
a. Remington: The Science and Practice of Pharmacy. 21st edition, 2005, University of the Sciences in
Philadelphia (editor), ISBN: 9780781746731.
b. Pharmaceutical Calculations by Howard C. Ansel and Mitchell J. Stoklosa. Lippincott Williams &
Wilkins; Thirteenth, North American Edition (September 1, 2011)
c. Allen, LV, Popovich, NG, and Ansel. HC Ansel’s Pharmaceutical Dosage Forms and Drug Delivery
Sytems. 9th edition, 2011, Lippincott Williams & Wilkins, ISBN: 978-0781779340.
12
1. Blackboard for Lectures and other supportive material and different Website addresses which
will be provided by the instructor as the topics are taught in the class.
2. http://pharmlabs.unc.edu/
3. www.emedicine.com
1. CD for British Pharmacopeia (B.P.),
2.
United States Pharmacopeia (U.S.P).
3.
British Pharmaceutical Codex (B.P.C).
Course Weekly Activities
Week
W-1
Sept 1
Intended Learning
Outcomes
Lab
Assignment/projects
1. Introduce the Importance of the
subject in profession of pharmacy
2. Enlist the course objectives and
the course outline
3. Familiarize with the ethics and
code of conduct.
4. Inform students about their
grade assessment schedule and
rules of absenteeism.
5. Provide information about
office hours of instructor.
Introduction to lab
equipment and
instruments to be
used in
compounding of
extemporaneous
preparations.
Given prescriptions
with
illegible
handwriting
regarding the dosage/
therapy, and given a
list of references,
select the reference
most likely to contain
information required
in this situation.
Lab safety Rules
Select any type of
medication label,
identify the following
information: generic
name, trade name,
strength of the
medication, special
storage
considerations, and
expiration date.
Lecture Topic
(chapter/section)
L1
Introduction
L2
Parts of Prescription
1.
2.
3.
W-2
Sept 8
L3
1.
2.
L4
W-3
Sept 15
Refill Information
L5
Handling
Prescriptions
Reading And
Checking the
prescription
Abbreviation and
Model prescription
1.
2.
Explain parts of
prescription
Identify labeling
requirements of the
various products
Identify controlled
substances in a
prescription.
Describe the rules
pertaining to refill of Rx
Analyze sample Rx’s to
identify needs of refil .
Describe the ethics of
handling Rx
Analyze and Identify
missing information in
Rx’s.
1. Ability to memorize and recall
abbreviations used in Rx’s
2. Reproduce a model Rx based on
case study and diagnosis.
13
Standards of
volumetric
devices
Collect a prescription
online and Interpret
drug orders.
L6
1.
Controlled
substances, history of
Pharmacy Law,
Schedules
2.
3.
4.
5.
W-4
Sept 22
L7
L8
DPC, Patents, FDA,
DEA,USP
.
1.
Learn the responsibilities
of the law enforcing
bodies like FDA and DEA.
Introduction to USP
1.
Labelling Techniques
2.
W-5
Sept 29
L9
Understand the meaning
of the term” Controlled
substances.”
Describe the term ”Drug
Control”.
Classification of
controlled substances
into schedules.
Memorize some
examples of drugs falling
into the five diiferent
schedules
Enumerate the history of
Laws enforced on Drugs.
1. Differentiate between the
labeling requirements related
to different dosage forms/
delivery systems.
2. Memorize specific auxiliary
labels frequently encountered
in most popular products
Labelling Of internal
and external use
products, Auxiliary
labelling.
Weighing and
measuring for
compounding
extemporaneous
preparation
1.
2.
Compounding a
prescription of
Piperazine Citrate
Elixirs B.P
Describe the mandatory
information required to
be written on labels
Differentiate between the
different types of labels
.
L10
Standards for
balances and
weights
Describe the different
methods of weighing and
measuring of substances.
Judge and select the
method of weighing
based on dosage.
14
Concentrations
and dilutions
Collect the names of
5 drugs belonging to
schedule I, II, III, IV
and V with their
details regarding their
class to which they
belong(category),The
rapeutic indications,
dosage, contra
indications and
toxicity
information.(Refer
standard books of
Pharmacology).
Given a prescription
containing
a
controlled
drug
substance, collect the
necessary
information to be
delivered
during
patient counselling.
W-6
L11
Oct 6-9)
(4 days)
Incompatibilities,
classification,
Physical
incompatibilities
1.
2.
3.
L12
Chemical and
therapeutic
incompatibilities
1.
2.
W-7
Oct 13
W-8
Describe the types of
incompatibilities
identified in
prescriptions.
Analyse the
prescription, identify
incompatibilities.
Suggest remedial
measures for the
most commonly
encountered
incompatibilities in
Rx’s.
Identify
the given Rx’s and
suggest remedies for
the same.
Analyze the
prescription, identify
incompatibilities.
Suggest remedial
measures for most
encountered
Rx’s.
List the Quality
Control tests to be
carried out on tablet
as a dosage form by
referring to the
United States
Pharmacopoeia.
Hajj Vacations
Oct-20
(1 day)
W-8
Oct 21
(4 days)
L14
Solids-Classification and
Advantages and
Disadvantages
1.
2.
3.
W-9
Oct 27
L15
Definitions of different class
of Tablets and their uses
1.
Describe the
different solid
dosage forms
along with the
relevant
additives used
in their
formulation.
Enumerate the
advantages and
disadvantages
of each of the
solid dosage
forms in
comparison
with other
dosage forms.
List applications
of the various
solid dosage
forms along
with suitable
examples
Define The
different
classes of
15
Compounding a
physical
incompatibility due
to liquefaction
Compounding a
physical
List all the
auxiliary
labels, the
auxiliary
label that
should be
placed on a
prescription
bottle or box
containing
suppositories,
solution,
suspensions
etc. to be
dispensed to a
patient.
Collect
information
regarding the
2.
W-10
Nov 3
W-11
Nov 10
L16
Capsules, Advantages,
disadvantages
L17
Powders, types, advantages
and disadvantages,
Enumerate the
advantages and
disadvantages
of capsules in
comparison
with other
dosage forms
1. Define The
different
classes of
powders
2. Differentiate
the types of
powders based
on their
ingredients and
applications
3. Enumerate
their
applications
1. Describe principle
behind formulation of
each type of powder
2. Differentiate between
the powders based on
their applications
3. Analyze the
properties of powders
and select ingredients
appropriately.
incompatibility
containing
indiffusible solids
types of
containers
(bottles)
available for
packaging of
liquid dosage
forms.
1.
L18
Ideal properties, internal and
bulk powders, effervescent
granules.
L19
Suppositories, Definitions,
advantages and
disadvantages
1.
Classification and properties
of suppository bases
1.
L20
tablets
Differentiate
the types of
tablets based
on their
ingredients and
applications.
2.
Define
suppositories.
Compare and
contrast
suppositories
by comparing
with other
dosage forms
based on their
advantages.
Differentiate
classes of
suppository
bases based on
their
16
Compounding a
chemical
incompatibility
containing
oxidisable
substances
Compounding an
incompatibility due
to immiscibility
(Castor Oil and
water emulsion).
Collect
information
to
differentiate
between a
liniment and
lotions, a cold
cream and a
vanishing
cream, a
eutectic
powder and
an
effervescent
powder.
Select, from a
list of
auxiliary
labels, the
auxiliary
label that
should be
placed on a
prescription
bottle or box
containing
suppositories
to be
dispensed to a
patient
2.
W-12
Nov 17
L21
1.
Liquids-definition,
classification, vehicles
2.
L22
1.
Additives used in Solutions
2.
properties.
Analyse
properties of a
drug and select
a suitable
suppository
base.
Define The
different
classes of
Liquids
Enumerate
their
applications
Define The
different
classes of
additives with
their
applications
List few
examples of
additives used
in each class
with their
concentrations.
Labelling of
prescription
containing
controlled
substances
Given a
group of
definitions,
select the
definition of
the term
syrup.
.
W-13
Nov 24
L23
Aqueous liquid preparation
1.
2.
L24
Non-aqueous Liquid
preparations
1.
2.
W-14
Dec 1
L25
Semisolids-classification,
advantages and
disadvantages, Types of
1.
Define The
different Types
of aqueous
solutions with
ingredients
Describe the
importance of
each
preparation
based on its
application.
Labelling of
external use
products
Given a list
of percentage
concentration
s, select the
percentage of
sucrose in
syrup, USP
Define The
different Types
of non-aqueous
solutions with
ingredients
Describe the
importance of
each
preparation
based on its
application.
Define
different types
of semi-solid
17
Revision
Given a list
of auxiliary
labels, select
semisolids.
2.
L26
Semisolids-properties and
selection of ointment bases,
Pastes and creams.
1.
2.
W-15
Dec 15
W-16
Dec 22
dosage forms.
Compare and
contrast them
by comparing
with other
dosage forms
based on their
advantages.
Define
ointments and
classify them.
Compare and
contrast
semisolid
dosage based
on their
advantages.
Suspensions-Definition,
Properties of ideal
suspensions, Classification,
Advantages and
disadvantages
1. Define suspensions
and classify them
2. Compare suspensions
with other dosage forms
based on their
advantages and
disadvantages
L28
Suspensions- additives in
suspensions ,Types of
suspensions, Sedimentation
1. Describe additives
used in suspensions with
their principles of
working.
2. Classify suspensions
based on their
properties.
3.Understand the
principle of
sedimentation and its
importance in stability of
suspensions..
L29
Emulsions-definitions,
classification and additives
1. Define emulsions and
classify them
2. Compare emulsions
with other dosage forms
based on their
advantages and
disadvantages
Emulsions-methods of
preparation
1. Enumerate the
methods of preparation.
2. Compare the methods
to judge their suitability
in preparation.
L27
L30
the auxiliary
label that
should be
placed on a
container in
which an
ointment is
dispensed
18
Revision
Final Exam
Given a
group of
statements,
select the
statement that
best describes
the
relationship
between the
rectal and the
oral dose of a
medication
Given a
formula for
preparation of
an emulsion,
calculate the
primary
emulsion
formula using
the wet gum
method
W-17
Dec-29
L31
Emulsions- listing of
evaluation tests
W-18
Jan 5
1. Enumerate the
evaluation tests
2. Identify the principles
involved in the
identification tests
Final Exams
D. Class Format:
students will read assignments before coming to class. It should be anticipated that class discussion may
require knowledge of the reading material and student who are not prepared may find class discussion
difficult to follow.
Prescription and Labelling
1. Given prescriptions with illegible handwriting regarding the dosage/ therapy, and given a list of
references, select the reference most likely to contain information required in this situation.
2. Select any type of medication label, identify the following information: generic name, trade name,
strength of the medication, special storage considerations, and expiration date.
3. Collect a prescription online and Interpret drug orders.
Controlled Substances
1. Collect the names of 5 drugs belonging to schedule I, II, III, IV and V with their details regarding their
class to which they belong(category),Therapeutic indications, dosage, contra indications and toxicity
information.(Refer standard books of Pharmacology).
2. Given a prescription containing a controlled drug substance, collect the necessary information to be
delivered during patient counselling.
Incompatibilities.
1. Identify incompatibilities in the given Rx’s and suggest remedies for the same.
Dosage Form
1. List the Quality Control tests to be carried out on tablet as a dosage form by referring to the United
States Pharmacopoeia.
2. List all the auxiliary labels, the auxiliary label that should be placed on a prescription bottle or box
containing suppositories, solution, suspensions etc. to be dispensed to a patient.
19
3. Collect information regarding the types of containers (bottles) available for packaging of liquid dosage
forms.
4. Collect information to differentiate between a liniment and lotions, a cold cream and a vanishing
cream, a eutectic powder and an effervescent powder.
F. Service learning/Interprofessional Education: (if applicable)
Not applicable
For the theoretical section of this course, there will be 2 examinations, Midterm, and Final exam. The
outcome of these exams will represent 65% of the final grade in the course.
Overall, the course will be graded as follows: Schedules for Midterm and Final exams will be announced by the
Committee for Academic affairs in consultation with relevant students’ committee.
Grading Scheme
Assessment
1.
2.
3.
4.
5.
Assessment task (eg. essay, test, group project, examination
etc.)
Week due
Proportion
of Final
Assessment
rd
5%
th
5%
Th
25%
Quiz #1
3 week
Quiz #2
8 week
Mid Term Exam
5 week
Lab Exam (lab experiment, presentation and assignments)
14 week
25%
Final Exam
End of
semester
40%
Total
th
100%
F. Attendance:
COMING IN LATE
G. Academic Dishonesty and Misconduct:
20
6.
Cheating in exams, quizzes, lab/small group sessions, from any source, like fellow student,
notes, electronic sources.
7.
Plagiarism: presenting work, words, ideas, presentations, assignments of others, in whole or in
part, in assignments, presentations or projects
21
22
DEPARTMENT OF PHARMACEUTICAL SCIENCES
Course Plan
Course Coordinator/Instructor:
Instructor: Dr. Michelyne Haroun, Dr Christophe Tatrant
Contacts:
7. Office No. 7
8. Office hours: S, M: 9:30- 10:30 T, W: 8:30-9:30 or by appointment.
9. Email and office contacts: [email protected], extension 4/1783/9823
College/Department: Faculty of Clinical Pharmacy/Department of Pharmaceutical Sciences
Course title and code: Pharmaceutical Organic Chemistry I / 2010112
Year and Semester: 1th Year/ 1th Semester
Credit hours: 3+1 (5 contact hours)
Pre-requisite: none
B:Course Description &Objectives
1. Aims of the Course:
Organic Chemistry I course is offered for pharmacy student to master the fundamental
principles of organic chemistry. It provides general concepts in the chemistry of hydrocarbons
including chemical bonding, classification, nomenclature, chemical structure, synthesis,
reactions of aliphatic organic compounds containing various functional groups (alkanes,
alkenes, alkynes, alcohols, ethers, carbonyl compounds, amines). Emphasis will be placed on
the mechanistic and stereo-chemical aspects of organic reactions. Selected examples of organic
compounds of medicinal or pharmaceutical interest will be presented. Practical session will be
devoted to the elucidation of molecule structure through spectroscopic analysis including
nuclear magnetic resonance, infra-red and mass spectrometry.
2. Briefly describe any course development objectives that are being implemented. (eg
23
increased use of IT or web based reference material, changes in content as a result of new
research in the field or feedback from peers and students)
Students will be taught how to use the electronic library resources. They will be strongly
encouraged to visit the library regularly in addition to the student resources of the following
website: http://mhhe.com/physsci/chemistry/carey/index.mhtml
This material would be beneficial for mastering the topics in organic chemistry
After successful completion of the course, the student would be able to:
A Describe chemical bonding, its biological and pharmaceutical applications and the structure
of different class of aliphatic organic compounds.
B Demonstrate knowledge in mechanistic understanding of some organic reactions.
C Predict the expected reactant, product and reagent in chemical reaction.
D Apply spectrometric methods for structure elucidation of organic compounds.
1. Required Textbook(s) :
Organic Chemistry, Francis Carey, Mc Graw Hill, 4th Edition, 2004 (will be sent to
students as a software copy).
2.
Additional References :
- Organic Chemistry, Paula Bruice, Mc Graw Hill, 6th edition, 2010.
- Organic Chemistry, T.W.G. Solomon’s, Wiley, 10th Edition, 2009.
- Spectrometric Identification of Organic Compounds, Robert M. Silverstein, Wiley, 8th
Ed, 2011.
3. Electronic Materials, Web Sites, etc.
http://mhhe.com/physsci/chemistry/carey/index.mhtml
http://www2.chemistry.msu.edu/faculty/reusch/VirtTxtJml/intro1.htm
http://www.kfu.edu.sa/ar/Deans/Library/Pages/books_2.aspx
4. Other learning material such as computer-based programs/CD, professional
standards/regulations: Chem Draw, SciFinder, Accelrys drug design database
24
C: Course Weekly Activities Tentative
Week
Lecture
W-1
Sept 1
L1
W-2
Sept 8
W-3
Sept
15
Topic
(chapter/section)
Syllabus Presentation
Intended Learning
Outcomes
L2
Chemical Bonding
(C.B.) (Ch.1)
L3
Chemical Bonding
(Ch.1)
L4
Chemical Bonding
(Ch.1)
L5
Alkanes (Ch.2)
1. Write the electron
configuration corresponding to a
neutral atom or to an ion derived
from it when given the atomic
number of any element between
hydrogen and argon in the
periodic table
2. Describe the difference
between ionic and covalent
bonding.
1. State the octet rule and discuss
its significance
2. Determine the direction of
polarization of a covalent bond on
the basis of the difference in
electronegativity of the atoms that
it connects.
3. Calculate the formal charges on
atoms in Lewis structures
4. Write the structures of organic
molecules using condensed
structural and bond-line formulas
1. Describe the resonance and
inductive effects
2. Describe different types of
intermolecular forces
1. Recognize the hydrocarbon
families, functionally substituted
derivatives of alkanes, and classes
of compounds containing the
carbonyl group
2. SP3 hybridization
3. Give the IUPAC names of the
unbranched alkanes having up to
10 carbon atoms
4. Given an alkane or
cycloalkane, write its IUPAC
name
5. Given the IUPAC name for an
alkane or cycloalkane, write its
structural formula
1. Recognize by common name
and structure the alkyl groups that
contain up to four carbon atoms
2. Identify and draw isomers
3. Comment on the stability of
primary, secondary and tertiary
radicals (most stable radical ?)
4. Understand the difference of
reactivity between chlorination
and bromination of alkane
L6
Alkanes (Ch.2)
25
Assignment
Lab
Reading
Chapter
Homework
on chemical
bonding
Introduction
to
Spectroscopy
Reading
Chapter
Infra-Red
Spectroscopy
Homework
on alkanes
W-4
Sept
22
W-5
Sept
29
L7
Alkenes (Ch.5)
L8
Alkenes (Ch.5 &Ch.6)
L9
Alkynes (Ch.9)
1. Write a structural formula and
a correct IUPAC name for an
alkene
2. SP2 hybridization
3. Recognize alkenes that can
exist in stereoisomeric forms, and
identify them as cis, trans, E, or Z,
as appropriate
4. Compare isomeric alkenes with
respect to their relative stability
according to the degree of
substitution and stereochemistry
at the double bond
1. Write a chemical equation
expressing the addition of each of
the following to a representative
alkene:
Hydrogen in the presence of a
suitable catalyst
Hydrogen halide (chloride,
bromide, iodide)
Water containing a trace of acid
Chlorine or bromine (with and
without water present)
2. State and give an example of
Markovnikov’s rule
3.Describe the preparation of
alkene by elimination reaction of
alcohol and alkyl halide
3. State and give an example of
Zaitsev’s rule.
4. Demonstrate knowledge in
mechanistic understanding of
reaction
5. Explain the following terms:
syn and anti addition,
regioselectivity, Halonium ion
1. Write a correct IUPAC name
and structural formula for an
alkyne
2. SP hybridization
expressing the addition of each of
the following to a representative
alkyne:
Hydrogen in the presence of a
suitable catalyst (formation of
alkane and cis-alkene)
Metal reduction of alkyne
(formation of trans alkene)
Hydrogen
halide
(chloride,
bromide, iodide) in the absence
(Markovnikov) and in the
presence of peroxide (antiMarkovnikov)
Water containing a trace of acid
(ketone formation via enol)
Chlorine or bromine (transdihalide alkenes and tetrahalide
alkane formation)
26
Drop quiz
on alkanes
Reading
Chapter
Infra-Red
Spectroscopy
Homework
on alkenes
Drop quiz
on alkenes
Reading
Chapter
Homework
on alkynes
IR problem
solving
W-6
Oct 69)
(4
days)
L10
Alkynes (Ch.9)
L11
Alcohols (Ch. 4)
L12
W-7
Oct 13
W-8
Oct-20
(1
day)
W-8
Oct 21
(4
days)
W-9
Oct 27
Alcohols (Ch. 15)
1.Write a chemical equation for
the alkylation of acetylene or a
terminal alkyne via the
corresponding carbanion
2. Write appropriate chemical
equations showing how to convert
an alkyne to either a cis alkene or
a trans alkene
3. Explain the use of lindlar
catalyst
1. Write a structural formula and
IUPAC name for an alcohol
2. Define the three classes of
alcohols
3. Explain how oxidation and
reduction relate to organic
compounds
4. Describe the oxidation reaction
of alcohols with appropriate
oxidizing agents (PCC, PDC,
KMnO4, K2Cr2O7)
1. Discuss the reactivity
difference between NaBH4 and
AlLiH4 (source of Hydride)
2. Discuss the preparation of alkyl
halides and esters from alcohols
3. Write a chemical equation for
the preparation of an epoxide
from an alkene, and predict the
product of the reaction of an
epoxide with a nucleophile
Drop quiz
on alkynes
1
H NMR
Spectroscopy
Reading
Chapter
Homework
on alcohols
Hajj Vacations
L14
L15
L16
Alcohols and ethers
(Ch. 15)
Aldehydes &Ketones
(Ch.11)
Aldehydes &Ketones
(Ch.11)
the preparation of an ether by the
Williamson method
2. Predict the products of the
cleavage reaction of ether.
1. Provide IUPAC name and
structural formula for an aldehyde
or a ketone
2. Describe how the polar nature
of the carbonyl group affects
nucleophilic additions to
aldehydes and ketones
3. Write an equation for the
hydration of an aldehyde or a
ketone,
the formation of an acetal and
cyclic acetal
1. Explain how acetal can be used
as a protecting group of carbonyl
of aldehyde and ketone
27
Reading
Chapter
Homework on
ehers
Drop quiz on
alcohols and
ethers
Reading
Chapter
Homework on
aldehydes and
ketones
1
H NMR
Spectroscopy
W-10
Nov 3
W-11
Nov
10
W-12
Nov
17
L17
Aldehydes &Ketones
(Ch.11)
L18
Carboxilic Acids
(Ch.19)
L19
Carboxilic acid
(Ch.19)
L20
Carboxilic acid
derivatives (Ch.20)
L21
Amines (Ch. 22)
2. How to restore the carbonyl of
aldehyde and ketone from acetal.
3. Show how an organometallic
compound can be used to form
new carbon-carbon bonds
the oxidation of an aldehyde
1. Explain the process of
enolization, and draw the enol
form of a specific aldehyde of
ketone
the aldol
3. Describe the Michael Addition
Witting reaction (alkene
preparation)
1. Provide an acceptable
systematic IUPAC name
describing the acidity of a
carboxylic acid
3. Explain the greater acidity of
carboxylic acids compared with
alcohols by using resonance
structures
4. Explain how substituents affect
the acidity of a carboxylic acid
1. Describe the preparation of a
carboxylic acid by carboxylation
of a Grignard reagent
2. Describe the preparation of a
carboxylic acid by hydrolysis of a
nitrile
3. Describe the reduction of a
carboxylic acid to give a primary
alcohol.
4. Describe the formation of an
acyl chloride from a carboxylic
acid
-halogenation reaction of
carboxylic acids
2. Write chemical equations for
the preparation of ester using acyl
chlorides or acetic anhydride
3. Show how the reaction of an
ester with a Grignard reagent can
be used to prepare a tertiary
alcohol
4.Describe the preparation of an
amide
1. Identify different class of
amines
2. Explain why alkylamines are
both weak base and good
nucleophile
3. Describing the preparation of
an alkylamine by alkylation of
28
1
H NMR
Problem
Solving
Drop quiz on
aldehydes and
ketones
Reading
Chapter
Homework on
carboxylic
acids
13
C NMR
Spectroscopy
13
C NMR
Problem
Solving
Drop quiz on
carboxylic
acids
Reading
Chapter
Practical Quiz
Unknown
Structure
Determination
W-13
Nov
24
W-14
Dec 1
W-15
Dec
L22
Amines (Ch. 22)
L23
Conformation of
alkanes and
cycloalkanes (Ch.3)
L24
Conformation of
alkanes and
cycloalkanes (Ch.3)
L25
Stereochemistry
(Ch. 7)
L26
Stereochemistry
(Ch. 7)
L27
Stereochemistry
(Ch. 7)
ammonia
4. Describe different ways to
form a carbon-nitrogen single
bond
1. Explain Gabriel synthesis for
the preparation of primary amines
the preparation of an alkylamine
by reduction of a nitrile,an imine
and an amide
3. Use a chemical equation to
describe the reaction of an amine
with an alkyl halide
4. Discuss the formation of
alkenes from a quaternary
ammonium hydroxide salt (antizaitsev): Hofmann elimination
1. Recognize and represent
conformations of particular
molecules by wedge-and-dash,
Newman projection, and
sawhorse formulas
2. Draw a chair conformation for
a cyclohexane derivative, clearly
showing substituent(s) in axial or
equatorial orientations as
appropriate
3. Know the meaning of the terms
eclipsed conformation, staggered
conformation, anti conformation,
and gauche conformation.
1. Understand the difference
between constitutional isomers
and stereoisomers
2. Understand how branching
affects the boiling point of an
alkane
1. Identify a chiral molecule by
locating a stereogenic center
2. Explain what is meant by the
terms enantiomer and
diastereomer
3. Draw perspective (wedge-anddash) representations of chiral
molecules
4. Describe how a plane of
symmetry relates to whether or
not a molecule is chiral.
1. Specify the absolute
configuration of a molecule using
the R-S notational system
2. Draw Fischer projections of
chiral molecules.
3. Explain the meaning of the
term meso form.
4. Explain optical activity as a
property of chiral molecules.
1. Give the number of
stereoisomers possible for a
29
Project
Homework on
amines
Reading
Chapter
Mass
Spectroscopy
Homework on
cycloalkane
conformation
Drop quiz on
stereochemistry
Reading
Chapter
Homework on
stereochemistry
Solving
Combined
Application
Problems on
Mass
Spectroscopy,
IR, 1H NMR
and 13C NMR
Presentation of
Unknown
15
L28
W-16
Dec
22
W-17
Dec29
L29
Nucleophilic
Substitution (Ch.8)
Nucleophilic
Substitution (Ch.8)
L30
Poster Presentation
L31
Revision
W-18
Jan 5
molecule having more than one
stereogenic center
2. Explain why addition reactions
to achiral alkenes give racemic
mixtures of products
1. Identify a reaction as being a
nucleophilic substitution and
predict the products
term bimolecular nucleophilic
substitution
3. Predict the stereochemical
result of an SN2 reaction
4. Predict the effect of steric
crowding on an SN2 reaction
term unimolecular nucleophilic
substitution.
2. Explain how carbocation
stability affects the rate of an SN1
reaction
3. Predict the stereochemical
outcome of an SN1 reaction
Structure
Determination
Project
Reading
Chapter
Homework on
SN2
Reading
Chapter
Practical Exam
Homework on
SN1
Final Exams
. Class Format:
Class will consist of lectures and in some instances class discussion of problems or other assignments. In addition,
student will be responsible for all material in reading assignments regardless of whether or not the material is discussed in
class. Since these reading assignments are provided before class, it is expected that students will read assignments before
coming to class. It should be anticipated that class discussion may require knowledge of the reading material and student
who are not prepared may find class discussion difficult to follow.
To be announced in due time
F. Examinations and Assessment:
During the semester, there will be announced classroom quizzes in advance. These quizzes include topics from the
lectures that are covered before the quiz. The quizzes represent 10% of the final grade in the course.
30
For the theoretical section of this course, there will be 2 examinations, Midterm and Final exam. The outcome of these
exams will represent 65% of the final grade in the course.
Overall, the course will be graded as follows:
Schedules for Midterm and Final exams will be announced by the Committee for Academic affairs in consultation with
relevant students’ committee
Grading Scheme
Asse
ssme
nt
1
2
3
4
5
6
7
8
9
Assessment task (eg. essay, test, group project,
examination etc.)
Week due
Proportion
of Final
Assessment
Quiz #1
5
5
Quiz #2
11
5
Practical Quiz
12
5
Unknown Structure determination project presentation
15
5
14 / 4, 5, 6,
9, 10, 12,
14
weekly
homework
Class activities/drop quizzes
Mid Term Exam (Final Schedule will be issued by
Academic Affairs committee)
5
Formative
25
Lab Exam
16
10
Final Exam
End of
semester
40
Total
100%
F. Attendance:
I expect you to be at every class. I often give information in class that is not found in the textbook. Attendance is one of
the most important work ethics in this profession. If you miss 25% of the total classes during the semester, you will be
dropped from the final exam.
COMING IN LATE will not allow to attend the class and you will be considered as absent!!
While it is mandatory to come on time in every class, I do realize that some logical circumstances may prevent you from
getting to class on time.
31
Students found to commit any of the above will be subject to disciplinary actions according to University Rules and
Regulations, mentioned in COCP Students’ Handbook
32
33
Department of Biomedical Sciences
Course plan
Physiology-1
A. General information
Course coordinator/instructor: Dr. Maitham Al Hawaj
Contact information:
Office location: Old classroom 1
Office hours:
Monday: 12:30 PM–01:30 PM
Tuesday: 08:30 AM–09:30 AM
Email:
[email protected]
[email protected]
College: College of Clinical Pharmacy
Department: Department of Biomedical Sciences
Course title (and code): Physiology-1 (2020111)
Year/semester: 1st year/1st semester
Credit hours: 2+1
Prerequisite: NONE
Schedule:
1. Male section:
 Lecture:
Monday from 08:30 AM–09:30 AM
Wednesday from 09:30 AM–10:30 AM
 Practical: Wednesday from 11:30 AM–02:30 PM
2. Female section:
 Lecture:
Monday from 10:30 AM–11:30 AM
Thursday from 07:30 AM–08:30 AM
 Practical: Tuesday from 11:30 AM–02:30 PM
34
B. Course description and objectives
Course aims:
This course provides students with the fundamental knowledge of human physiology that serves as an essential
foundation for many PharmD courses. It covers the physiological basis for: cell, muscle, nerve, blood,
autonomic/central nervous systems, cardiovascular system and respiration
Course objectives:
Upon successful completion of this course the student will be able to achieve the following objectives regarding
topics covered in this course:
A. Describe functions and mechanisms regarding human cells, tissues, organs and systems.
B. Correlate the normal functional mechanisms with common physiological disorders.
C. Determine and interpret different diagnostic/laboratory values and measurements.
C. Learning Resources
Required textbooks:
1. Hall JE. Textbook of Medical Physiology. 12th ed.
2. Ganong WF. Review of Medical Physiology. 23rd ed.
Electronic material:
Blackboard Website
D. Course Weekly Activities (Tentative Schedule)
Week
(No.)
Date
(of Week)
W1
Sep 1
W2
Sep 8
W3
Sep 15
W4
Sep 22
W5
Sep 25
W6
(4 days)
Oct 6
W7
Oct 13
W8
(4 days)
Oct 21
W9
Oct 27
W10
Nov 3
Lecture
(No.)
L1
L2
L3
L4
L5
L6
L7
L8
L9
L10
L11
L12
Topic
Syllabus
Introduction to physiology
Cellular transport
Cellular transport
Blood
Blood
Blood
Blood
Excitable tissues (nerve)
Excitable tissues (nerve)
Excitable tissues (muscle)
Excitable tissues (muscle)
Practical (Lab)
Comment
Holidays
L13
L14
L15
L16
L17
L18
Autonomic nervous system
Cardiovascular system
35
W11
Nov 10
W12
Nov 17
W13
Nov 24
W14
Dec 1
W15
Dec 8
W16
Dec 15
W17
Dec 22
W18
Dec 29
W19
Jan 5
L19
L20
L21
L22
L23
L24
L25
L26
L27
L28
L29
L30
L31
L32
L33
L34
Respiratory system
Respiratory system
Respiratory system
Respiratory system
Respiratory system
CNS
CNS
CNS
CNS
CNS
CNS
Revision
Revision
Final exams
E. Class Format
students will read assignments before coming to class. It should be anticipated that class discussion may require
knowledge of the reading material and student who are not prepared may find class discussion difficult to
follow.
F. Library Assignments (Homework)
Group of students will be assigned to a specific topic (a disease state under this course). They should write the
pathophysiology of that disease state in a paper. The homework assignment represents 2% of the final grade.
G. Service learning
Students will be classified into groups for service learning for measurement of blood pressure and determination
of blood group in some schools. The service learning represents 3% of the final grade.
36
H. Examinations and Assessment
During the semester, there will be announced and pop quizzes. These quizzes include topics from the lectures
that are covered before the quiz. The quizzes are worth % of the final grade in the course. There will be 1
practical (lab) exam, which represents 20% of the final grade. In addition, there will be 2 theoretical
examinations, midterm and Final exam. The midterm exam represents 25% while the final exam represents 40%.
Schedules for practical (lab), midterm and final exams will be announced by the Committee for Academic affairs
in consultation with relevant students’ committee. The following table shows the grade distribution.
Assessment
Pop quizzes
Announced quiz 1
Announced quiz 2
Homework assignment
Service learning
Midterm exam
Practical (lab) exam
Final exam
Total
Percentage
5%
2.5%
2.5%
2%
3%
25%
20%
40%
100%
I. Attendance
I expect you to be at every class. I often give information in class that is not found in the textbook. Attendance is
one of the most important work ethics in this profession. If you miss 25% of the total classes during the
COMING IN LATE:
J. Academic Dishonesty and misconduct
16. Cheating in exams, quizzes or small group sessions, from any source, like fellow student,
notes, electronic sources.
17. Plagiarism—presenting work, words or ideas of others, in whole or in part, in assignments,
presentations or projects.
18. Falsifying tempering records of attendance, false excuses for absence.
20. Non-adherence to instructions regarding class discipline, dress code etc,
and Regulations, mentioned in COCP Students’ Handbook.
37
38
Department of Biomedical Sciences
Course Plan
Institution
College/Department
College of Clinical Pharmacy/Department of Biomedical Sciences
A Course Identification and General Information
1. Course title and code: Anatomy and Histology- I / 2020112
2. Credit hours
2 hours (1 + 1)
3. Program(s) in which the course is offered.
(If general elective available in many programs indicate this rather than list programs)
Pharm. D program
4. Name of faculty member responsible for the course
Dr. Muhammad Shahzad Chohan
5. Level/year at which this course is offered
1st Level / 1st Year
6. Pre-requisites for this course (if any)
………………….
7. Co-requisites for this course (if any)
………………….
8. Location if not on main campus
……………………
39
B Objectives
1. Summary of the main learning outcomes for students enrolled in the course.
Upon successful completion of the course the student will be able to describe the structures of Human skeleton, organs,
muscles, vessels and nerves. Recognize histology of cells, tissues and organs; and describe the basic human
embryology with effect of drugs on various phases of intrauterine development.
2. Briefly describe any plans for developing and improving the course that are being implemented. (eg increased use
of IT or web based reference material, changes in content as a result of new research in the field)
 Extensive use of Blackboard for the lectures and supportive material.
 Students will be encouraged to ask questions and initiate discussions during the lecture to carry out interactive
learning, where student's interest in the subject can be enhanced.
C. Course Description (Note: General description in the form to be used for the Bulletin or Handbook should be attached)
1 Topics to be Covered
List of Topics
No of
Weeks
Contac
thours
A) Lectures
Introduction to Anatomy and Anatomical terms.
Human skeleton and muscles
1
1
Anatomy of Thorax and its contents 1
1
Anatomy of eye and ear, its gross aspects and relations 1
Concept of histology, study of epithelial tissue 1
1
Connective tissue , their histological descriptions. 1
1
Histology of cartilages 1
1
Histology of spongy and compact bones and muscles . 1
Joints of the body 1
Blood vessels 1
1
1
1
1
Embryology: Gametogenesis, fertilization. 1
1
Embryology: development of embryo week by week 3
3
Embryology: Fetus and Placenta 2
2
B) Practical (Laboratory)
Demonstration of Upper Limb bones and muscles 1
3
Identify the upper limb muscles and bones 1
3
Demonstration of upper limb vessels 1
3
Upper limb, Identify the vessels. 1
3
40
Demonstration of Lower Limb bones and muscles 1
3
Identify the Lower limb bones and muscles 1
3
Demonstration of lower limb vessels 1
3
Lower limbs: Identify the arteries, veins and nerves 1
3
Identify the lungs and Heart along its main features
Practical spotting of limbs, lungs and heart
Discussion of Case-based clinical scenario questions related to drugs
on embryo (teratogenesis).
Discussion of Case-based clinical scenario questions related to
Gross anatomy
Discussion of Case-based clinical scenario questions related to
Histology
1
1
3
3
1
3
2
6
2
6
2 Course components (total contact hours per semester):
Lecture:
Tutorial:
Laboratory
15
Nil
45
Practical/Field
work/Internship
Other:
Nil
Nil
3. Additional private study/learning hours expected for students per week. (This should be an average :for the
semester not a specific requirement in each week)
4 Hours per week
4. Development of Learning Outcomes in Domains of Learning
For each of the domains of learning shown below indicate:

A brief summary of the knowledge or skill the course is intended to develop;

A description of the teaching strategies to be used in the course to develop that knowledge or skill;

The methods of student assessment to be used in the course to evaluate learning outcomes in the
domain concerned.
a. Knowledge
(i) Description of the knowledge to be acquired
1.
2.
3.
Upon successful completion of the course the students should be able to:
Describe the structures of Human skeleton, organs, muscles, vessels and nerves.
Recognize Histology of cells, tissues and organs.
Describe the basic human embryology with effect of drugs on various phases of intrauterine
development.
(ii) Teaching strategies to be used to develop that knowledge
1.
Discussion.
41
2.
3.
4.
Power point presentation.
Student’s assignment.
Video.
(iii) Methods of assessment of knowledge acquired
1.
2.
3.
Quiz Examinations (MCQ’s and Short Essay Questions).
Mid-term and Final examinations (MCQ’s and Short Essay Questions).
Evaluation of the student's assignment.
b. Cognitive Skills
(i) Description of cognitive skills to be developed
Student will be able to apply knowledge of Anatomy for understanding of disease process and its
diagnosis.
(ii) Teaching strategies to be used to develop these cognitive skills
1.
2.
Case-based clinical scenario questions in exams related to the course topics.
Encouraging the student to discuss with other students what they learn in the class every day.
(iii) Methods of assessment of students cognitive skills
Written (Single Best Response Type MCQ's of C2 (interpretation) and C3 (Problem Solving)
level, short questions in Quizzes, Midterm exam and final semester exam.
c. Interpersonal Skills and Responsibility
(i) Description of the interpersonal skills and capacity to carry responsibility to be developed
1.
2.
3.
By the completion of the course the students will be able to:
Demonstrate tolerance and acceptance for criticism from fellow students.
Be regular and more punctual in academic schedules.
Work constructively in a group, cooperating with their leaders and seniors.
(ii) Teaching strategies to be used to develop these skills and abilities
1. Conducting discussions in the class.
2. Active learning.
3. Work individually and in group in practical sessions
(iii) Methods of assessment of students interpersonal skills and capacity to carry responsibility
1.
2.
Continuous follow up of the attendance for regularity and punctuality.
Continuous oral discussions.
d. Communication, Information Technology and Numerical Skills
(i) Description of the skills to be developed in this domain.
1.
2.
By the completion of the course the students will be able to:
Operate computers and search the worldwide web more skilfully to find anatomy and histology
related material.
Interact with Blackboard learning program.
(ii) Teaching strategies to be used to develop these skills
42
1.
2.
3.
Small group discussion.
Lectures are available on blackboard (word documents and presentations).
Inform students with the most important websites of the course.
(iii) Methods of assessment of students numerical and communication skills
1.
2.
Evaluation of student communications during office hours.
Continuous discussions with student (Oral discussion).
e. Psychomotor Skills (if applicable)
(i) Description of the psychomotor skills to be developed and the level of performance required
1.
2.
After the completion of the course the student will be able to
Identifying the normal tissues.
Proper disposal of biohazardeous material after practical in dissection hall.
(ii) Teaching strategies to be used to develop these skills
1.
Power point presentations.
2.
Clinical case discussions.
3.
Demonstrations and showing the students different structures of human body both on cadaver and on
anatomy models for identification.
(iii) Methods of assessment of students psychomotor skills
1.
2.
Ask the individual student to identify the structures in human cadaver and on Anatomy models.
Ask case based clinical questions.
5. Schedule of Assessment Tasks for Students During the Semester
Assessment
1
2
3
4
5
etc.)
Week due
Proportion of
Final
Assessment
Quiz-1
3rd week
5%
Mid-Term Examination
8th week
25%
Quiz-2
5th week
5%
Practical
14th week
25%
Final Examination
16th week
40%
D. Student Support
1. Arrangements for availability of teaching staff for individual student consultations and academic advice.
(include amount of time teaching staff are expected to be available each week)
5 Hours / week
43
E Learning Resources
1. Required Textbook(s) :
1- Clinical Anatomy by regions, Richard S, Snell. Publisher; Lippincott Williams &
Wilkins. Ed.9th, 2009
2-Junqueira's Basic Histology,Text and Atlas, Luiz Junqueira and Jose Carneiro.
Publisher; McGraw-Hill Medical. Ed. 12th, 2009.
3- Langmans Medical Embryology, Thomas W. Sadler. Publisher; Lippincott
Williams & Wilkins. Ed. 11th, 2009.
1-Grant's Atlas of Anatomy, Anne M.R. Agur and Arthur F. Dalley. Publisher;
Lippincott Williams & Wilkins. Ed. 12th, 2008.
2- Neuroanatomy: An Illustrated Colour Text, Alan R. Crossman David Neary.
Publisher; Churchill Livingstone. Ed. 4th, 2010.
3- Gray's Anatomy for Students, Richard L. Drake, A. Wayne Vogl, and Adam W.
M. Mitchell. Publisher; Churchill Livingstone. Ed. 2nd, 2009.
Web Sites: http://www.bartleby.com/107/
Anatomy computer-based CD material including, videos.
F. Facilities Required
Indicate requirements for the course including size of classrooms and laboratories (ie number of seats in
classrooms and laboratories, extent of computer access etc.)
1. Accommodation (Lecture rooms, laboratories, etc.)
Lecture room with at least 70 seats.
2. Computing resources
Computers and Internet access for the students to use their Laptops in the University campus.
3.
Other resources (specify --eg. If specific laboratory equipment is required, list requirements or attach
list)
Equipments required:
Ser. No.
Name
44
1
Human Torso Model
2
Human Embryology models
3
Skeleton model
F. Attendance:
I expect you to be at every class. I often give information in class that is not found in the textbook. Attendance is one of
the most important work ethics in this profession. If you miss 25% of the total classes during the semester, you will be
dropped from the final exam.
COMING IN LATE will not allow to attend the class and you will be considered as absent!!
While it is mandatory to come on time in every class, I do realize that some logical circumstances may prevent you from
getting to class on time.
Students found to commit any of the above will be subject to disciplinary actions according to University Rules and
Regulations, mentioned in COCP Students’ Handbook
45
46
DEPARTMENT OF…………….
Course Outline
Course Coordinator/Instructor: Dr. Asia Taha/Dr. Ahmed Ragaa
Contacts:
1.Office No: 1078
2. Office hours: 4 hours, Tuesday, Wednesday, thursday
3. Email and office contacts: [email protected], 035899826,
College/Department: Clinical Pharmacy/Biomedical sciences
Course title and code: Biochemistry-1, 2020113
Year and Semester: first semester, level-1
Credit hours: 2+0 per week
Pre-requisite; None
1. Aims of the Course; Aim of the course is to provide the student comprehensive knowledge about the
biomolecules of human body which will form the basis for understanding various disease processes and
their diagnosis.
2. Briefly describe any course development objectives that are being implemented. (eg increased use of
IT or web based reference material, changes in content as a result of new research in the field or
- Encouraging students to interact more with blackboard
- Encouraging students to interact more with university library and to read
the course related text books
- Encouraging students to interact more with Websites of Biochemistry
A. Recognize the fundamental theoretical concepts of biochemistry.
47
B. Identify applications of the biochemistry in the life
C. Define and describe the chemistry of biomolecules including; carbohydrates, amino acids,
proteins, nucleic acids, lipids, steroids and enzymes.
D. Recognize the general structures and functions of biological molecules.
E. Demonstrate the structural differences between DNA and RNA.
F. Outline the functions of enzymes functions.
G. Describe enzyme kinetics and inhibition.
Required Textbook(s): a)Harper's Biochemistry, Robert K. Murray.
b) Lumbrt Stryer's Biochemistry
2. Additional References : a) Principles of Biochemistry by lehninger, Nelson and Cox ;
b) Lipincott textbook in Biochemistry
3. Electronic Materials, Web Sites, etc.
a)Web-CT/blackboard learning program
b) Pubmed website
c) Biomednet Website
d) science direct
CD material including
a)Biochemistry of life
b)Harper's Biochemistry, Robert K. Murray.
c)Lumbert Stryer's Biochemistry
d)PDQ Biochemistry ;R. Roy Baker, Robert K. and Murray, MD, 2001
BC Decker Inc Hamilton • London
C: Course Weekly Activities
Week
Topic (chapter/section)
Lab
No lab
1
L1
Introduction and general
knowledge about biomolecules
2
L2
L3
3
L4
L5
Biochemistry and medicine
Carbohydrate definition,
nomenclature and classification
Isomerism and optical activity
Chemical reactions of
monosaccharides
Sugar derivatives and
disaccharides
L6
Assignment Notes
1
48
4
L7
L8
5
L9
L10
6
L11
L12
PolysaccharidesHomopolysaccharides
Polysaccharides –
heteropolysaccharides
Lipids: Introduction, biological
importance and classification
Alcohols and Fatty acids definition and classification and
functions
Fatty acids-classification
continued, lipids-definition and
types
Chemical properties of simple
lipids
7
HAJJ VACATION
8
9
L13
L14
10
L15
L16
11
L17
L18
12
L19
L20
13
L21
L22
14
L23
L24
15
16
17
18
L25
L26
L27
L28
L29
L30
L31
L32
Compound lipids:
phospholipids
Compound lipids: glycolipids
and lipoproteins
Steroids: definition and types
Physical and chemical
properties of important steroids
Proteins; definition, structure of
amino acids, physical
properties of amino acids
Chemical properties of
aminoacids, formation of
peptides & proteins
Properties of proteins
Separatory techniques for
proteins and amino acids
Classification of proteins
Classification of proteinscontinued
Enzymes-structure,
classification and nomenclature
mechanism of action of
enzymes
enzyme kinetics
Enzyme specificity
Control of enzyme activity
Enzyme activation
Enzyme inhibition
Uses of inhibitors types of
isozymes
Some clinical cases
Revision
2
3
4
49
Annexure 1, 2, 3,4,5,
1. Water acts as a universal solvent
2. List and discuss the most common Triacylglycerols
3. Cholesterol is an alcohol and/or steroid
4. Separate albumin and globulin using column chromatography
D. Class Format:
students will read assignments before coming to class. It should be anticipated that class discussion may require
knowledge of the reading material and student who are not prepared may find class discussion difficult to
follow.
Assignments on carbohydrate structure, lipids, steroid structure, protein separation techniques, nucleic acids and
enzyme inhibitors
F. Service learning:(if applicable)
For the theoretical section of this course, there will be 2 examinations, Midterm, and Final exam. The outcome
of these exams will represent 80% of the final grade in the course.
Overall, the course will be graded as follows:
Schedules for Midterm and Final exams will be announced by the Committee for Academic affairs in
consultation with relevant students’ committee
Grading Scheme
Asses
sment
1
2
3
4
5
etc.)
Quiz #1
5th
Proportion
of Final
Assessment
5%
Mid Term Exam
10th
30 %
12th
10 %
Quiz # 2
Week due
13
th
End of
semester
Final Exam
Total
5%
50 %
100%
F. Attendance:
50
COMING IN LATE
Fellow student, notes, electronic sources.
51

Kingdom of Saudi Arabia

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