2006 - Health Care Professionals - Dartmouth
Transcription
2006 - Health Care Professionals - Dartmouth
Department of Surgery 2006 Annual Report Administration Richard W Dow, MD, FACS Chair Daniel Walsh, MD Vice Chair Residency Program Director Kerry Ryan, MBA Director Linda Barie Administrative Manager Audrey Carr Budget and Grant Coordinator Christina Cole Assistant to the Chair From left to right—Back row: Kerry Ryan; Christina Cole; Richard Dow, MD; Donald Likosky, PhD. Front row: Audrey Carr, Dawn Robinson, Linda Barie, John Higgins. (Not pictured: Daniel Walsh, MD; Debra Ludington) Donald Likosky, PhD Departmental Epidemiologist Contents Department of Surgery Sections Cardiothoracic Surgery General Surgery Neurosurgery Ophthalmology Otolaryngology Pediatric Surgical Specialties Plastic Surgery Transplantation Surgery Urology Vascular Surgery Maxillofacial Surgery John Higgins Database Manager 6 8 10 12 14 16 18 20 22 24 26 Program Highlights Thoracic Surgery Program Trauma Program 27 28 Office of Surgical Education Medical Student Education Programs Training Programs 30 31 Sponsored Research Clinical Trials Federal & Corporate 32 33 Awards 34 Invited Speakers 34 Publications 35 Debra Ludington Clerkship Program Coordinator Dawn Robinson Residency Program Administrator Department of Surgery Donald Likosky, PhD Assistant Professor of Surgery Surgical Research Lab Jeffery Bergeron, DVM Assistant Professor of Surgery P Jack Hoopes, DVM, PhD Associate Professor of Surgery and Medicine Chair’s Letter E ach year the preparation of the Annual Report reminds me of the exciting, vibrant, and dynamic environment that characterizes our Medical Center, the Department of Surgery and the entire field of health care. Just as an anecdote, we recently re-transplanted a patient as part of a “four person swap.” It was a situation where two couples were incompatible to donate to their spousal partners; however, they were appropriately matched for a transplant to the spouse of the other couple and all four people were anxious to proceed. One of the recipients had previously received a kidney transplant—from another live donor—about 25 years ago. Her “in-hospital” recovery in the 1980’s extended to three weeks, but she was anxious to leave the hospital and continue her recovery at home just three days after this second transplant. Her story is simply illustrative of the developments over the past decades in anesthesia, perioperative care, immunosuppression, infection control, and the management of the common co-morbidities. Progress in providing safe, effective, and reliable surgical care that has been nothing short of breathtaking. In the pages of this report, you will see evidence of these changes as they are incorporated into the fabric of the surgical care which we provide to our patients. Under the collaborative leadership of Drs. Tony DiScipio and Mark Fillinger, we’ve established an Aortic Center—offering endovascular and open surgical repairs and reconstructions not envisioned only a few years ago. Our Cochlear Implant Program offers an ability to hear to those who were born without, or who had lost this key sense. Our Pancreas Transplant Program offers patients freedom from insulin, normalized glycemic control, and the hope of forestalling the ravages of diabetes. Our Bariatric Surgical Program provides an effective option to improve the quality and duration of life for the morbidly obese patient. Our Comprehensive Breast Care Program offers a variety of strategies to improve the outlook for patients with breast cancer—and accomplishes this goal in the context of preserving the patient’s body image and sense of self. Our Lasik and refractive surgery program offers the opportunity to achieve unaided normal vision. Our Radiosurgery Program, using technologies both spectacularly complex but functional and reliable, enables new approaches to control a variety of cranial and extracranial lesions. And, these are only a few highlights of the dramatic developments in health care—it’s truly an exciting time and our Transforming Medicine Campaign is aptly named. While I’m proud and excited about all the technical and care accomplishments of members of the Department of Surgery, I’m equally proud of their attention to the issues of Patient Safety, Quality Improvement, and Patient Satisfaction. We’ve enthusiastically embraced the 100,000 Lives Campaign, developed safeguards around patient identification and confirmation of operative site and plan, established protocols to address the several strategies known to reduce the incidence of surgical site infection, operationalized policies focused on the prevention of line associated sepsis, and initiated a host of other activities to improve the safety and reliability of the care we provide. These are exciting times and we look forward to the upcoming year with even greater enthusiasm. Sincerely, Richard W Dow, MD, FACS Chair, Professor of Surgery Department of Surgery OR Cases Department of Surgery Gross Revenue (in millions) 12,000 11,000 10,000 9,000 8,000 7,000 6,000 5,000 4,000 3,000 2,000 1,000 120M 110M 100M 90M 80M 70M 60M 50M 40M 30M 20M 10M FY01 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Department Of Surgery Statistics Associate Research Clinical Provider Projects Trials Faculty Residents Section CT 7 7 General 21 3 34 4 2 Maxillofacial 1 Neurosurg 4 3 5 1 Ophthal 10 3 2 ENT 7 1 1 1 Peds Surg 7 2 2 Plastics 7 1 2 2 2 Transplant 3 Urology 6 2 6 2 1 Vascular 9 2 2 10 15 TOTAL 82 24 50 23 21 Publications 14 32 2 33 4 6 17 11 6 11 30 166 Outpatient Visits OR Cases (full-time faculty) (full-time faculty) 1,919 12,391 1,703 4,444 32,608 18,093 5,227 10,008 1,897 12,553 7,325 108,168 709 2,805 129 793 1,316 1,224 937 1,249 273 944 935 11,314 Department of Surgery Sections Cardiothoracic Surgery T he Section of Cardiothoracic Surgery is now The Section of Cardiac and Thoracic Surgery. William C Nugent Jr, MD Section Chief Professor of Surgery The Migration is Complete The past twelve months have seen both functional and structural changes within the Section of Cardiac and Thoracic Surgery. As our practice responds to the clinical and technological challenges of today’s health care system, the Cardiac and General Thoracic initiatives have continued to grow and redefine themselves. Many of the dreams of last year have matured into the realities of today as we have worked together to provide the very highest quality surgical care to patients with diseases of the chest. all appropriate diagnostic and surgical therapies including 3-D aortic imaging, hypothermic circulatory arrest and endovascular aortic repair. When surgical intervention is Anthony DiScipio, MD appropriate, a specific team of nursing, anesthesia, perfusion, and critical care personnel has gained the necessary experience to now consider these complex cases “routine.” Results have been excellent as we now perform over 35 cases annually. The Aortic Center at Dartmouth Under the directorship of Dr. Anthony DiScipio, Dartmouth-Hitchcock Medical Center has formally instituted a multidisciplinary approach to patients with complex diseases of the aorta. Patients with aneurismal diseases of the aorta harbor life threatening conditions which, in order to repair, require some of the most sophisticated surgical interventions performed today. The Aortic Center at Dartmouth is the result of the collaborative efforts of Cardiac Surgery, Vascular Surgery, Cardiovascular Medicine and Diagnostic Radiology. This has allowed patients to benefit from General Thoracic Surgery Over the past year, general thoracic surgery at DHMC has continued to flourish. As our surgical volume continues to increase, our nursing and paraprofessional staff has gained experience and expertise in the care of these patients. Endobronchial therapy (laser, stents, brachytherapy) is now routinely available in the OR or Endoscopy Suite. This service has matured under the leadership of Dr. David Johnstone and Dr. Peter DeLong of Pulmonary Medicine, who have worked to provide seamless coverage and useful collaboration in Cardiothoracic Surgery Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M FY01 6 Cardiothoracic Surgery Cases 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report this challenging population of patients. Esophageal surgery, both malignant and benign, has gradually increased over the past year. Interest in minimally invasive Lawrence Dacey, MD approaches to this disease remains, and we hope to gradually move forward with that in the next year. Finally, the multidisciplinary thoracic oncology clinic is expected to begin this fall, with all specialties available in the same location, to provide patients with efficient comprehensive lung cancer care. This is the result of a year of collaborative effort between the various sections involved and Norris Cotton Cancer Center. Outcomes Cardiac surgery remains the most closely scrutinized specialty in all of medicine. Healthcare payers and their patients have insisted on transparency in outcomes and thus have expectations of low mortality and morbidity rates, short lengths of stay, and high patient satisfaction ratings. In keeping with this movement towards transparency, DHMC now provides patients web access to our cardiac surgical outcomes in a patient friendly format. Outcome data comes directly from the Northern New England Cardiovascular Disease Study Group, allowing our results to be compared regionally and can be accessed at www.dhmc.org/ QualityReports/list.cfm?metrics=CT. Cardiothoracic Surgery J Pearce Beissinger, PA-C Instructor in Surgery Jean Clark, ARNP Instructor in Surgery Lawrence Dacey, MD Associate Professor of Surgery and Community & Family Medicine Anthony DiScipio, MD Assistant Professor of Surgery Robert Dunton, MD Assistant Professor of Surgery Carlos Garcia, MD, MHA Adjunct Assistant Professor Thomas Gervais, PA-C Instructor in Surgery Ryan Hafner, PA-C Instructor in Surgery David Johnstone, MD Associate Professor of Surgery Elizabeth Maislen, ARNP Instructor in Surgery Jimmy Maneksha, MBBS, MS Instructor in Surgery John Sanders, Jr, MD Professor of Surgery Patricia Uhlig, PA-C Instructor in Surgery www.dhmc.org/goto/surgery_annual_report 7 Department of Surgery Sections General Surgery T he past year was marked by the addition of Dr. Gina Adrales to the Division of Minimally Invasive Surgery. Dr. Adrales has taken on the role of the Director of the Hernia Center and will be taking a growing leadership role in surgical simulation to support our residency training program. Dr. Kimberly Grafton relocated this summer to California. She is deeply missed by our Section and her patients. We have been fortunate to hire Dr. Kari Rosenkranz, who completed her General Surgery residency at Dartmouth in 2005, and has just finished a Fellowship in Breast Surgery at MD Anderson Cancer Center. Richard J Barth, Jr, MD Section Chief Associate Professor of Surgery Patient Care Patient care remains organized under the Division of Trauma and Acute Surgical Illness, led by Dr. John Sutton; the Division of Minimally Invasive Surgery, directed by Dr. William Laycock; and the Division of Surgical Oncology, directed by Dr. Richard Barth. General Surgery patients continue to be very satisfied with the care they receive. Our patient satisfaction scores are significantly above the DHMC mean, placing us ninth out of 52 DHMC sections. Seventy-seven percent of patients reported their overall rating of their provider was “excellent.” The Referring Provider Satisfaction Survey also noted General Surgery’s results were well above the DHMC mean. The Division of Minimally Invasive Surgery has increased its volume of hernia repairs with the addition of Dr. Adrales. We have also initiated a fellowship position in laparoscopic surgery. The Division of Surgical Oncology formally began the Interdisciplinary Breast Clinic in January. We now offer breast cancer care in one location in the Norris Cotton Cancer Center with many providers seeing the patients during one visit. This program has continued to grow and patients have access to several measures of success of the breast program on our DHMC web page. Dr. Rosenkranz will be traveling to Manchester one day each week to reach out with her expertise in breast cancer care to patients in southern NH. The Division of Trauma and Acute Surgical Illness continues to work with a large interdisciplinary team to expand and improve trauma and acute surgical care. Our newest trauma surgeon, Dr. Rajan Gupta, has brought a wealth of experience in both clinical care and trauma program coordination and is sharing his expertise to continue to build on our solid Trauma Program. During this past year, three General Surgeons have taken on formal patient care responsibilities with the Critical Care Service. General Surgery Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 8 General Surgery Cases FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report General Surgery Education Dr. Sam Finlayson continues in his position of Assistant Director of the General Surgery Residency Program. Education demands the concerted efforts of several faculty members. Dr. Paul Kispert continues to balance the critical questions that arise during the Morbidity and Mortality conference with his own style of humor. Drs. Finlayson, Kispert and Barth also lead resident teaching conferences on a bi-weekly basis. Drs. Burchard and Henriques co-direct the surgery clerkship for medical students. Research Dr. Finlayson has been mentoring the work of several residents, leading to three presentations on surgical outcomes at the American College of Surgeons meeting. The Division of Surgical Oncology continues its multidisciplinary efforts in the treatment of pancreatic cancer patients. In collaboration with our colleagues in medical oncology and radiation oncology, Drs. Thomas Colacchio, John Sutton and Barth demonstrated that neoadjuvant chemoradiation can be used to enable patients with borderline or unresectable pancreatic cancers to undergo complete tumor resections with a low local recurrence rate. Dr. Sarah Greer was awarded first prize in the resident paper competition at the New England Surgical Society meeting for her presentation of our experience. Dr. Burton Eisenberg published several papers on the treatment of gastrointestinal stromal tumors and was invited to discuss the management of these tumors at several national meetings. Dr. Eisenberg also has continued to work with general surgery residents in the lab on his NIH grant studying the molecular basis of action of Gleevec. Gina Adrales, MD Assistant Professor of Surgery Lori Alvord, MD Assistant Professor of Surgery Assoc. Dean, Student & Minority Aff. Kenneth Burchard, MD Prof. of Surgery and Anesthesiology Thomas Colacchio, MD Professor of Surgery Burton Eisenberg, MD Professor of Surgery Samuel Finlayson, MD Asstistant Professor of Surgery and Community & Family Medicine Benjamin Forbush, MD Assistant Professor of Surgery Rajan Gupta, MD Assistant Professor of Surgery Jeffrey Harnsberger, MD Assistant Professor of Surgery Horace Henriques, III, MD Associate Professor of Surgery Paul Kispert, MD Assistant Professor of Surgery and Anesthesiology William Laycock, III, MD Associate Professor of Surgery Jean Liu, MD Assistant Professor of Surgery Elizabeth McCabe, ARNP, MS Instructor in Surgery Ellen McKinnon, ARNP Instructor in Surgery Joseph Meyers, MD Adj. Assoc. Professor of Surgery Maureen Quigley, ARNP, MS Instructor in Surgery Nick Perencevich, MD Adj. Assoc. Professor of Surgery Frank Pindyck, MD Associate Professor of Surgery Kari Rosenkranz, MD Assistant Professor of Surgery John Sutton, Jr, MD Professor of Surgery www.dhmc.org/goto/surgery_annual_report 9 Department of Surgery Sections Neurosurgery T he Section of Neurosurgery completed its move into new offices this spring, and coupled with our new clinical space at 3C, this long-awaited transition has provided much needed room for both the patient-care and academic missions. Completion of our library—in storage for the past two years—is slated for later this summer. Patient Care Our newest faculty member, Dr. Kadir Erkmen, has rapidly come up to full speed, with his subspecialty training in skull-base neurosurgery bringing new capabilities to the Section and the Medical Center. He is also heading up the cerebrovascular program and together with Dr. Tim Lukovits, in Neurology, and Dr. Cliff Eskey, in Interventional Radiology, led advances in the Medical Center’s Stroke Program. He has been on the faculty of national skull-base surgery workshops, and has already had a major impact on our training program. Other new faces in the Section include Sharon Morgan, ARNP, and Alyssa Pearl, PA, who, in developing our associate provider initiative, have enabled the Section to clinically grow. David Sargent, PA, will be joining them in September. Dr. Nathan Simmons has managed to both increase his clinical activity in pituitary, spine, tumor, and general neurosurgery, while at the same time David Roberts, MD Section Chief Professor of Surgery training for and successfully competing in the Lake Placid Ironman Triathlon this summer. Dr. Perry Ball continues his work in spine and in general neurosurgery as well as remaining an integral part of the Critical Care service. He continues to work on the Admissions Committee of DMS and has been promoted to Lieutenant Colonel in the Medical Corps of the Army Reserve. Dr. Henry Schmidek, whose retirement this past fall was honored by a research forum, published the 5th edition of his Operative Neurosurgical Techniques (the most widely used neurosurgery textbook), capping off a most distinguished academic career. Dr. Tina Duhaime and Dr. Susan Durham have expanded their pediatric neurosurgery practice to outpatient clinics in Manchester, NH. Dr. Duhaime’s NIH funding for investigation in head injury was successfully renewed, and she was elected to membership in the Society of Neurological Surgeons this past year. Dr. Durham (a new mom this spring) has entered her second year in the CECS program. Education The Neurosurgery residency has had another outstanding year. Our most recently graduated chief resident, Dr. Kendall Lee, has joined the neurosurgery faculty of the Mayo Clinic in Rochester, Neurosurgery Gross Revenue (in millions) Neurosurgery Cases 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 10 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report MN. During the past year he completed his AANS/CNS Research Fellowship work, and added to his previous distinctions a Mentoring Award from the Society for Neuroscience and from the Korean Neuroscience Society, the Presidential Award (for the “Best Paper”) at the meeting of the Society for Neuroscience. Dr. Patricia Quebada, this year’s chief resident, won the national AANS/CNS Joint Section for Pediatric Neurosurgery Traveling Fellowship, which she used to study at the University of Toronto this spring. Dr. Scott Lollis was successful in his grant application to the NIH for work in magnetic resonance elastography. Dr. Symeon Missios was awarded a Top Ten Poster award at the national meeting of the AANS. In undergraduate www.dhmc.org/goto/surgery_annual_report medical education, the Section had a very successful initiation of a new DMS elective in neurosurgery which was oversubscribed. Programmatically, Dartmouth enrolled the first three patients in the current Neuropace multicenter national trial using closedloop intracranial stimulation for the treatment of intractable seizure disorders. The joint Radiation Oncology/Neurosurgery Radiosurgery Program brought the newest technology in this field (The Trilogy system) into clinical use this spring. Our program, in the use of robotic instrumentation for stereo tactic procedures using the SurgiScope operating system, one of whose patent licenses is held by Dartmouth, remains the largest in this country. Advanced Neuromodulation Systems, Plano, TX, is finalizing licensing agreements for two additional Dartmouth patents involving deep brain stimulation. Neurosurgery Perry Ball, MD Associate Professor of Surgery and Anesthesiology Kadir Erkmen, MD Assistant Professor of Surgery Sharon Morgan, ARNP, MSN Instructor in Surgery Alyssa Pearl, PA-C Instructor in Surgery David Sargent, PA Instructor in Surgery Nathan Simmons, MD Assistant Professor of Surgery Research The Section is represented on eight editorial boards, two international advisory boards, and two national advisory boards. The chairmanship of the editorial board of the Journal of Neurosurgery was held in Dartmouth this past year. Stereo tactic and Functional Neurosurgery, with its editorial offices at Dartmouth, completed full transition to electronic manuscript submission and review, and in its four years since moving here has seen a three-and-a-half-fold increase in its impact factor. 11 Department of Surgery Sections Ophthalmology U nder the leadership of Dr. Donald Miller, our Refractive Surgery Program has been re-launched and expanded and is now on site for all phases of care. We have acquired the state of the art Wavelight Allegretto laser. Our refractive patients will now receive their initial ophthalmic evaluations, laser treatment and postoperative care at DHMC. Nancy Patterson will serve as the Refractive Surgery Coordinator. We have been very pleased with the growing popularity of this service and our outstanding clinical outcomes. Dr. Christopher Chapman, Section Chief, has established the Dartmouth Electrophysiologic Testing Center which will include ERG, EOG, VEP and color vision testing. Kim McQuaid, COMT, is the coordinator for clinical services. Dr. Sandra M. Johnson continues to provide clinical service at DHMCManchester. She provides comprehensive ophthalmology, cataract, and glaucoma consultation on a monthly basis. Dr. Alexandra Elliott, pediatric ophthalmologist, has expanded her children’s practice into the new CHaD facility. We have added specialized ophthalmic testing equipment for children to her service. We now offer sub-specialty clinics in pediatric neuroophthalmology and pediatric optometry within CHaD as well. Dr. Susan Pepin will add expertise in pediatric neuro- Christopher B Chapman, MD Section Chief Assistant Professor of Surgery and Pediatrics ophthalmology and Dr. Christopher Fields in optometry. Dr Christopher Soares will also provide medical and surgical consultation for pediatric patients. The Section’s new OCT-3 instrument has been installed and is operational for optic nerve and macular imaging. We expect the ocular coherence tomography to be most helpful in following the clinical course of our glaucoma and retina patients. Tom Monego serves as head of Ophthalmic Photography and Imaging. Faculty Research Dr. Susan Pepin was appointed a Harmes Scholar in the Department of Surgery last year. Dr. Pepin is conducting research in vision and Alzheimer’s disease and has presented at local, regional, and national meetings. Dr. Michael Zegans is principal investigator for the national study, “Steroids in Corneal Ulcers Trial.” Dr. Zegans is a National Eye Institute investigator in biofilm formation and pseudomonas infections. Dr. Zegans also serves as a reviewer for Archives of Ophthalmology and the American Journal of Ophthalmology. Dr. Chapman has initiated studies in retinal cell transplantation and a new clinical trial for diabetic retinopathy. Dr. Rosalind Stevens serves as expert consultant to Helen Keller International. Ophthalmology Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 12 Ophthalmology Cases FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Dr. Stevens has also organized the Orbis International eye care project in conjunction with Dartmouth Medical School’s Global Health Initiative project in Tanzania. Dr. Stevens will also be coordinating the Flying Eye Hospital project in Vietnam later this year. Dr. Stevens serves on the advisory board for the Cybersight Telemedicine project. Dr. Stevens will continue to serve as senior instructor for the annual Academy of Ophthalmology Trauma course. Dr. Miller is co-investigator for the Steroids in Corneal Ulcers Trial and serves as lecturer for the annual Academy of Ophthalmology review course on eye trauma. Dr. Miller has presented locally at grand rounds programs as well as regionally and nationally. Dr. David Campbell, chief of the glaucoma service, lectures at the Lancaster course held annually and is conducting studies in pseudo exfoliation and glaucoma as well as developing approaches in glaucoma. Dr. Chris Fields has conducted annual eye care missions into Nicaragua and has been honored nationally for his efforts. Dr. Fields will be providing an elective course on International Ophthalmology for Dartmouth Medical Students. Douglas Jabs from the Wilmer Ophthalmic Institute at Johns Hopkins was this year’s visiting Curts professor. Dr. James Tsai, an international expert in glaucoma, presented new information on neuro-protection. Dr. Jack Witcher, an international expert on corneal ulcers, presented issues surrounding corneal ulcers in the developing world. Dr. William Anninger, from The Children’s Hospital of Philadelphia, presented “Retinopathy of Prematurity Issues in the 21st Century.” The Future The Section has completed the initial phases of developing a three year residency training program in Ophthalmology. In discussions with both our referring physician partners and national leaders, we have the support and commitment required to launch the highest quality training program possible. Ophthalmology David Campbell, MD Professor of Surgery Alexandra Elliott, MD Assistant Professor of Surgery Chris Fields, OD Instructor in Surgery Sandra Johnson, MD Associate Professor of Surgery Peter Lapre, OD Instructor in Surgery Donald Miller, MD Assistant Professor of Surgery Susan Pepin, MD Assistant Professor of Surgery and Pediatrics John Petrowski, III, OD Instructor in Surgery William Rosen, MD Associate Professor of Surgery Christopher Soares, MD Adjunct Assistant Professor of Surgery and Instructor of Surgery Rosalind Stevens, MD Associate Professor of Surgery Michael Zeagans, MD Associate Professor of Surgery and Microbiology & Immunology Grand Rounds and Hosted Meetings Our monthly Grand Rounds at the Hanover Inn or DHMC continue to be well attended by our referring ophthalmologists. Topics include: Color Vision, Case studies in Neuro-Ophthalmology, Tumor Conference, Uveiis and Orbital disease. Dr. www.dhmc.org/goto/surgery_annual_report 13 Department of Surgery Sections Otolaryngology T he Section of Otolaryngology continues to grow and change to meet the needs of our local and regional patient base. This past year has seen the addition of Dr. Daniel Morrison, as an otologist and neurotologist, and Dr. Mark Smith in pediatric otolaryngology. Dr. Smith will be developing a dedicated pediatric otolaryngology service, the first of its kind for DHMC. Both of these additions have greatly improved access to care for patients with otologic concerns. After serving as section chief for 11 years, Dr. J.Oliver Donegan stepped down from that position in June of 2006. He continues his full-time practice in general otolaryngology and we look forward to many years of ongoing expert involvement in medical and surgical care, education, and research. He leaves behind a Section that is clinically very strong, financially viable, and poised to continue to grow and develop in many ways. Stepping into the section chief position is Dr. Morrison. Daniel Morrison, MD Section Chief Assistant Professor of Surgery Patient Care Clinically, we continue to do what we do best—that is, to deliver the highest quality comprehensive otolaryngology care in New England. Victoria Keetay, PhD heads an Audiology division that is second to none. The head and neck surgical oncology service continues to grow. Our skull base surgical capabilities are considerable with Drs. Benoit Otolaryngology Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M Education Under Dr. Morrison’s leadership, the Otolaryngology section will be venturing into the world of full-time otolaryngology resident training. Several hurdles in the residency application process have been cleared and an initial decision by the otolaryngology residency review committee is expected in February. Running parallel to this effort is a vigorous clinical research emphasis within the division. Drs. Paydarfar and Gosselin simultaneously received the Harmes Scholarship last year and have been actively pursuing lines of research within the field of head and neck surgical oncology. Drs. Morrison and Smith also have active lines of research in progress. This has resulted in several presentations Otolarnygology Surgery Cases 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 14 Gosselin and Joseph Paydarfar sharing expertise in anterior skull base, Dr. Smith in craniofacial reconstruction and Drs. Glenn Johnson and Morrison in lateral skull base procedures. (The addition of Dr. Kadir Erkmen to the section of Neurosurgery has been a vital step in this effort.) The cochlear implant program, under Dr. Johnson’s able leadership, continues to strengthen, especially in the area of pediatric implants. Under Dr. Smith’s guidance, we expect the pediatric otolaryngology service to flourish. We have set the bar high for ourselves, and continue to meet and exceed our goals. FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report at national meetings and publications in peer reviewed journals. The division has solidified relationships with the VA Outcomes Group and their otolaryngologist, Dr. Louise Davies. Dr. Davies is a fully participating Section member, has several publications in print or pending, and will play a large role in the residency program as research director. As the Section becomes more focused on the educational process, we have expanded our involvement in medical student education with plans to further augment this activity. A curriculum for the rotating surgical intern has been developed and the role of the visiting University of Vermont otolaryngology resident has been refined. Otolaryngology Louise Davies, MD Assistant Professor of Surgery and Community & Family Medicine Peter Dixon, PA Instructor in Surgery J Oliver Donegan, MB, BCh Professor of Surgery JJ Benoit Gosselin, MD Associate Professor of Surgery Glenn Johnson, MD Associate Professor of Surgery Joseph Paydarfar, MD Assistant Professor of Surgery Mark Smith, MD Assistant Professor of Surgery and Pediatrics Audiology Program Julie Johnson, AuD Instructor in Surgery Victoria Keetay, PhD Assistant Professor of Surgery Maria Stella McHugh, MA-CCC Instructor in Surgery Leah Mosenthal, MEd Instructor in Surgery Michael Norris, MA-AuD Instructor in Surgery Cynthia Nulton, MS-CCC Instructor in Surgery Erin Pospychala, CCC-A Instructor in Surgery www.dhmc.org/goto/surgery_annual_report 15 Department of Surgery Sections Pediatric Surgical Specialties W ith a comprehensive team finally in place in 2006, the Section of Pediatric Surgical Specialties, which includes Pediatric General and Thoracic Surgery, Pediatric Neurosurgery, and Pediatric Urology, was able to focus all of its attention on its mission: to provide outstanding emergent, maintenance, and preventive health care to the children we serve, to educate and support their families, to advance our disciplines by innovative research, and to train future health care providers. Patient Care The successful recruitment of a second Pediatric Urologist, Dr. Daniel Herz, completed our ‘two of every specialty’ quest and enables the Section to provide aroundthe-clock pediatric coverage in all three surgical specialties. Dr. Herz trained in Pediatric Urology at the Hospital for Sick Children, in Daniel Herz, MD Toronto, Ontario, and brings added expertise in the area of minimally invasive urologic procedures. In order to improve patient access and convenience, each specialty added clinics at the CHaD outpatient facility in Laurie Latchaw, MD Section Chief Associate Professor of Surgery and Pediatrics Manchester this year. Pediatric General and Thoracic surgeons are available in Manchester one day a week, Pediatric Urologists two days a week, and Pediatric Neurosurgeons twice a month. In addition, Dr. Laurie Latchaw and Dr. Paul Merguerian continue to perform day surgical procedures at the Manchester Ambulatory Surgery Center. The Section also provides patients with highly specialized treatments and multidisciplinary clinics. Dr. Susan Durham offers a clinic to evaluate and treat lesions and injuries of peripheral nerves in both children and adults. Dr. Ann-Christine Duhaime performs deep brain stimulation and now provides the added safety of intraoperative brainstem monitoring. Working together with Dr. Doug Hyder and Dr. Candice Aitken, Dr. Duhaime established a multidisciplinary approach to the treatment of pediatric brain tumors. Dr. Daniel Croitoru, a world renowned expert and creator of the minimally invasive repair of pectus excavatum deformities, established a chest wall deformity program that is continuing to grow and recently began to offer shared medical appointments. Dr. Latchaw, along with Neonatology and Maternal Fetal Medicine, provides a comprehensive consultation for parents with prenatal diagnosis of congenital anomalies. Pediatric Urology provides sophisticated urodynamic studies and Pediatric Surgery Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M FY01 16 Pediatric Surgery Cases 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report innovative nonsurgical treatment of VUR for their patients. Education Educational activities for the Section of Pediatric Surgical Specialists included didactic and informal sessions with residents in General Surgery, Neurosurgery, Urology, and Pediatrics. Dr. Merguerian gave Urology Grand Rounds in May 2006, Dr. Croitoru gave General Surgery Grand Rounds in August 2006, and Dr. Durham gave Pediatric Grand Rounds in February 2006. The Section’s physicians and nurse practitioners traveled across the globe presenting and participating in specialty specific conferences. Dr. Merguerian presented to both the American Urological Association and American Academy of Pediatrics. Dr. Durham presented at the annual meeting of the American Association of Neurologic Surgeons, and Dr. Duhaime served as an invited speaker and visiting professor at numerous conferences and institutions as far away as the International Neurotrauma Society Meeting in The Netherlands and as close as Richmond Middle School in Hanover, NH. As a testament to our mission to train future providers, three DHMC surgical residents, Dr. Erin Rowell, Dr. Dimitrios Nikas, and Dr. Sean Corbett have been accepted into fellowships in Pediatric Surgery, Pediatric Neurosurgery, and Pediatric Urology, respectively. Research Research productivity by Section members was high this year. Dr. Croitoru published two papers in peer reviewed journals. Dr. Merguerian had two papers accepted for publication in 2006, and received a scholarship to pursue his Masters in Clinical Science at the CECS program starting in the fall of 2006. He continued to serve as the Director of the Section of Urology Research Program and mentor the Urology residents assigned www.dhmc.org/goto/surgery_annual_report to their laboratory year. Dr. Herz, the new Pediatric Urologist, who joined the Section from Mount Sinai Medical Center in New York, will pursue his laboratory research in bladder smooth muscle and urothelial cell tissue engineering for use in genitourinary reconstruction at DHMC. Dr. Duhaime is the Resident Research Coordinator for the Section of Neurosurgery. She continues her research in traumatic injury to the immature brain and has present outside funding as well as additional grant applications awaiting review. Recent productivity from her research includes three book chapters, seven peer-reviewed journal articles and three additional abstracts submitted. She has an active laboratory with a post-doctoral fellow as well as one of the Neurosurgery residents. She is also the mentor for Dr. Durham, as Dr. Durham has applied for a K 08 grant. In addition, Dr. Durham was awarded the Harmes Scholarship by the Department of Surgery for her study entitled “An Analysis of Head Acceleration Impact in Helmeted Alpine Sports.” Section Highlights Dr. Merguerian, as Chair of the Resource Committee for the CHaD Ambulatory Clinic and Dr. Duhaime, as Chair of the CHaD Radiology, Anesthesia, and Surgical Specialties Committee, were named to the new CHaD Operations committee. Dr. Duhaime continues to serve as Secretary of the Joint Section for Pediatric Neurosurgery of the American Association of Neurological Surgeons. In addition, she served on the Nominating Committee for the American Society of Pediatric Neurosurgeons. Dr. Latchaw was elected to membership in the New England Surgical Society. Ms. Sharon Haire, ARNP, is an Associate Professor for Clinical Instruction for the University of New Hampshire School of Nursing responsible for pediatric inpatient nursing education. Pediatric Surgical Specialties Pediatric General and Thoracic Surgery Daniel Croitoru, MD Associate Professor of Surgery and Pediatrics Sharon Haire, ARNP, MSN Instructor in Surgery Pediatric Neurosurgery Ann-Christine Duhaime, MD Professor of Surgery and Pediatrics Susan Durham, MD Assistant Professor of Surgery and Pediatrics Pediatric Otolaryngology Mark Smith, MD Assistant Professor of Surgery and Pediatrics Pediatric Urology Christine Danielson, CPNP Instructor in Surgery Daniel Herz, MD Assistant Professor of Surgery and Pediatrics Paul Merguerian, MD Professor of Surgery and Pediatrics 17 Department of Surgery Sections Plastic Surgery T he Section of Plastic Surgery continues to integrate improvement work in our daily activities. Our goal is to ensure our patients can be seen when and by whom they choose. We expanded our Shared Medical Appointment (SMA) initiative where groups of patients are seen together for consultation. Patients find they create an optimal learning environment and improve access to visits. Providers find they facilitate shared decision making with patients and improve efficiency. Donna Seiffert, RN, and Sharon Kuiken, RN, published an excellent article on SMAs in the Plastic Surgical Nursing Journal. In support of the SMA initiative, DHMC has approved a project manager and dedicated space with adjacent exam rooms which is available to groups at DHMC offering SMAs. Last year we embraced the concept of a surgeon booked into two rooms in the main OR. We expanded this initiative into our minor surgery suites, resulting in the elimination of provider down-time while rooms were being turned over. We incorporated weekly team ‘huddles’ into our practice this year whereby physicians, nurses, and secretaries review upcoming appointments and surgeries to identify potential errors in scheduling (overbooking, under booking, etc.). This has resulted in less work toxicity, Carolyn Kerrigan, MDCM, MSc Section Chief Professor of Surgery improved team satisfaction, and improved communication that has led to a better understanding of our co-workers’ roles and how our actions affect the whole patient experience. In the spring we initiated collaborative participation in Dartmouth’s CECS Microsystems course. This brought together the Section of Plastic Surgery, Department of Orthopedics, and Section of Rehab Medicine to address the need for a multidisciplinary hand service at DHMC. Our premise was that the highest quality patient centered care and resident education can be delivered in a multidisciplinary setting where providers work together to meet the needs of these patients. The Section also continues to pilot a project to make web based health surveys available to our patients so they can selfreport a health history and quality of life prior to a clinical visit - for more timely and focused “face-to-face” care. Education Our ACGME accredited residency training program expanded to a three-year format. Two external rotations have been established to complement the experience. The first rotation is burn care at the University of Southern California and the second rotation is a private practice experience in conjunction with the Maine Medical Center. Plastic Surgery Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M FY01 18 Plastic Surgery Cases 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Research Several research projects have been initiated in our Section this year. Dr. Renee Comizio began a review of breast reconstruction cases and Dr. Christopher Jensen initiated a study on the post bariatric patient undergoing body contouring surgery. Dr. Christopher Demas is working with industry to assess the utility of DIRI (thermal imaging) as a tool for planning perforator flap surgery. Dr. E. Dale Collins has recently been named as the PI on a multimillion dollar grant from the Foundation on Informed Medical Decision Making. This project focuses on implementing shared decision making in General Internal Medicine and further integrating it into the breast cancer population. Dr. Collins is also the clinical PI on an NCI grant to develop a platform for patient reported outcomes in oncology at DHMC. Dr. Mitchell Stotland has three research projects underway. His first project is examining novel dosing regimen for botulinum toxin in an effort to achieve a permanent paralysis effect (in collaboration with Dr. Jeffrey Cohen, Neurology). His second project involves exploring fMRI signal patterns in response to facial deformity (in collaboration with Anne Krendl, PhD, at Dartmouth Psychological and Brain Sciences.) His third project is The Psychological and Social Effects of Glabellar Botox Cosmetic® (botulinum toxin type A) Injections. In addition, Cynthia Metzler, RN, was awarded a quality grant to work with Dr. Stotland to develop “Patient-Held Health Documents” (PHDs) for Craniofacial Clinic patients to improve their organization and processing of information. Dr. Joseph Rosen is working on two grant projects. His first project is to develop a healthcare system for Vietnam using a windows based hand held platform for a distributed networked telemedicine system (funded by Microsoft Corporation.) His second project is the evaluation of various simulation systems for a range of threats against America such as transportation accidents, natural disasters, nuclear and biological attacks (supported by the Institute of Security and Technology Studies). Plastic Surgery Forst Brown, MD Emeritus Active Professor of Surgery E Dale Collins, MD Associate Professor of Surgery and Community & Family Medicine Christopher Demas, MD Associate Professor of Surgery Gerald Doherty, PA Instructor in Surgery Joseph Rosen, MD Professor of Surgery and Radiology Mitchell Stotland, MD, CM Assistant Professor of Surgery and Pediatrics Simone Topal, MD Instructor in Surgery Physician Highlights Dr. Carolyn Kerrigan has served as President-Elect of the Plastic Surgery Educational Foundation and will assume the responsibilities of President of this foundation for the 2006-2007 year. Dr. Christopher Demas continues the development and expansion of the Cosmetic Surgery program at DHMC and Dr. Rosen has been active with the reconstruction of soldiers returning from Iraq through his activities at the Walter Reed Medical Center. Dr. Stotland is completing his degree at the Center for Evaluative Clinical Sciences. He also coordinated our first annual Radford C. Tanzer, MD, Scientific Day. Dr. Collins has been an invited speaker at national forums to show case integration of “Shared Decision Making and Computerized Patient Self Assessment” for women being treated at DHMC’s Comprehensive Breast Program. www.dhmc.org/goto/surgery_annual_report 19 Department of Surgery Sections Transplantation Surgery: Pancreas & Kidney Transplant D David Axelrod, MD Surgical Director of Kidney and Pancreas Transplant Assistant Professor of Surgery and Community & Family Medicine uring the past year, the transplant program at Dartmouth-Hitchcock Medical Center has reached several exciting milestones. For the first time, the total number of kidneys transplanted exceeded 50 in a 12 month period. This represents an important threshold for the program and establishes DHMC as a major provider of transplant services in Northern New England. We have also successfully performed the first pancreas transplant in New Hampshire in October 2005. This marked the initiation of a successful program which has thus far eliminated the need for insulin in ten patients with diabetes mellitus. Renal Transplantation Kidney transplantation remains a core competency of the DHMC solid organ transplant program. During the previous 10 years, DHMC has established itself as a leader in the care of renal transplant patients. DHMC’s results, using an innovative immunosuppression regimen designed by Dr. Michael Chobanian, were recently presented at the World Transplant Congress. There, we reported on our experience with over 200 transplant patients. Among these patients, over 75% were managed with a single immunosuppression medicine rather than the standard three medication cocktail. Transplant Surgery Gross Revenue (in thousands) 3,000K 2,700K 2,400K 2,100K 1,800K 1,500K 1,200K 900K 600K 300K Transplant Surgery Cases 350 315 280 245 210 175 140 105 70 35 FY01 20 Despite this minimalist approach, the overall rate of kidney rejection was <3% and patients did exceptionally well. This report was one of the largest series ever reported for this approach. The past 12 months have witnessed important changes designed to improve efficiency of care. A newly designed kidney intake process has dramatically reduced the time from evaluation to being placed on the waiting list. In addition, most patients require only a single visit to DHMC to be listed for transplant, leading to improved patient satisfaction and referrals. Once transplanted, patients are cared for using a new clinical pathway which has reduced length of stay nearly 40%. Despite this short stay, overall kidney graft survival exceeds 98% among patients transplanted this year. Over the next year, we expect continued growth. We plan to initiate satellite clinics to improve patient referrals from distant points around New Hampshire including Nashua and the sea coast. In addition, we have scheduled the first donor swap in which two kidney recipients that have willing but incompatible donors will exchange kidneys. These procedures will be performed simultaneously and promises to expand access to kidney transplant to a greater number of patients in need. FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report We anticipate future growth in this business as the institutional initiatives in the areas of gastroenterology and hepatology further develop. Pancreas Transplant The pancreas transplant program has grown rapidly during its short life span. Among the ten patients who have received a pancreas, six were performed after a previous kidney transplant and four were performed as part of a combined kidney/ pancreas transplant. Overall, the program has been very gratifying. Currently, 100% of patients and organs are surviving. In addition, no patient has required a single unit of insulin once they have left the operating room. This success has led to a growth in interest in the program and currently 20 patients are waiting for an acceptable organ. Non-Transplant Surgery Members of the Section have also participated in the institutional program to provide state of the art, collaborative care to patients with liver disease and liver cancer. A variety of operative approaches are now offered to liver patients including laparoscopic radio frequency ablation. The technique offers the opportunity to treat and potentially cure liver cancer even in patients with very poor liver function. www.dhmc.org/goto/surgery_annual_report Transplantation Surgery Michael Chobanian, MD Associate Professor of Surgery and Pediatrics Richard Dow, MD Professor of Surgery Promotional & Educational Activities This year, the Section has developed a new, patient-friendly website. We are also participating in the transparency initiative and are publicly reporting our outcomes following kidney and pancreas transplantation. We are pleased to report that at one and three years, outcome at DHMC has significantly eclipsed the national average. The Section has also developed an interactive CD educational tool with the support of the Quality Research Grant Program. It is the hope that this CD will improve the effectiveness and efficiency of the discharge process following renal and eventually pancreas transplantation. Looking Ahead DHMC is becoming a more widely recognized multi-organ transplant program serving the population of Northern New England. Over the next year, we plan to reach out further into the community to ensure that all New Hampshire patients who can benefit from transplantation are afforded this opportunity. This commitment to serving the needs of this population has led to our request for, and subsequent approval of, a liver transplant center by the United Network for Organ Sharing which controls organ distributions. We hope to be able to initiate a clinical program in liver transplantation in the near future. 21 Department of Surgery Sections Urology T he Section of Urology enjoyed a year of professional and staff stability and significant growth in clinical productivity and case diversity. Already established as a regional referral service in oncology and voiding dysfunction, the Section expanded its tertiary repertoire in the areas of reconstruction, male reproductive medicine, and obstructive uropathy. Improvements in surgical volumes, especially in the areas of stone disease and obstructive uropathy, and an increase in new patient appointments, reflect the Section’s commitment to timely, comprehensive service to the DHMC community. William Bihrle, MD Section Chief Associate Professor of Surgery Patient Care Urology has completed a successful year in terms of improving care to our patients. Over the past year, we have continued to work on improving access to our patients. Kelley Hamill Lemay, NP, joined Urology in February of 2005, and has worked with Dr. Ann Gormley to improve access for Kelley Hamill Lemay, NP our female urology and voiding dysfunction patients. Dr. John Heaney and Dr. John Seigne, aided by Laura Stempkowski, NP, continue to expand the GU oncology program, providing comprehensive evaluation and treatment to a widening community of patients and physicians. With two experienced laparoscopic surgeons, the Institution is uniquely positioned to remain on the forefront of this important and evolving approach to the treatment of GU malignancies. Collaborating with his colleagues in diagnostic radiology, Dr. Seigne has established a dedicated PSA/prostate biopsy clinic which will be adding another dedicated clinic this fall in the Norris Cotton Cancer Center. The laparoscopically-assisted live donor nephrectomy program continues to expand under the guidance of Dr. Seigne and represents an example of successful collaboration with the Section of Transplantation Surgery. Dr. Lori Lerner continues to provide a minimally invasive laser-based option for the treatment of BPH (benign prostatic hyperplasia). Employing holmium laser energy, obstructing prostatic tissue is either ablated or enucleated, resulting in decreased hospitalization and shortened convalescence. Dr. Ajay Nangia has brought vasectomy procedures from the OR’s minor procedure room to our clinic’s new procedure room, which is allowing better access to this service every Friday. Urology Gross Revenue (in millions) Urology Cases 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 22 FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Our operating block is increasing this fall to match our growing demand of surgical cases, which will improve our surgery wait times. As a Section, we continue to look at ways to improve access and care to our patients. Education The Urology RRC of the ACGME approved Dartmouth’s petition to train two residents per year, completing a transition begun by Drs. Heaney and Gormley four years ago. The approval recognizes the growth in clinical GU services at DHMC and the important addition of the Concord Hospital affiliation. Eight residents—two in the research year—allows greater flexibility in the educational block and guarantees a more uniform clinical experience for our trainees. Hosting four DMS subinterns this summer, each of whom plans a career in urology, speaks to the beguiling nature of the specialty and the mentoring of a staff committed to education. Dr. Nangia, our student clerkship director, deserves credit for the growing local interest in our specialty. Dr. Dan Herz, a pediatric urologist coming from Mt. Sinai Medical Center in New York, joined Dr. Paul Merguerian in the Section of Pediatric Surgery, solidifying what has become a very strong aspect of the residency program. Faculty Activities Section faculty remain generously active in regional and national organized urology; we count no fewer than 10 officer and committee assignments in our various societies. Dr. Gormley, Vice President of the Society of Female Urology and Urodynamics, has been invited to sit on the AUA Residency Training Task Force; she continues as her Society’s editor for the Journal of Urology. Dr. Gormley and Dr. Lerner delivered the “Take Home Message” synopsis for urodynamics and BPH respectively, at this year’s annual AUA meeting. Dr. www.dhmc.org/goto/surgery_annual_report Lerner was named to represent the New England Section in the AUA Leadership Program. Climbing the organized infertility ladder, Dr. Nangia chairs the Ethics Committee of Lori Lerner, MD the American Andrology Association and is a new board member of the Society for the Study of Male Reproduction. Dr. Seigne recently delivered a state of the art presentation on penile cancer at the annual meeting of ASCO. He continues to represent New Hampshire on the NES - AUA Board of Directors and sits on the AUA Superficial Bladder Cancer Guidelines Panel. Urology E Ann Gormley, MD Professor of Surgery John Heaney, MB, BCh Professor of Surgery Kelly Hamill Lemay, ARNP Instructor in Surgery Lori Lerner, MD Assistant Professor of Surgery Ajay Nangia, MBBS Assistant Professor of Surgery and Obstetrics & Gynecology John Seigne, MB Associate Professor of Surgery Laura Stempkowski, ARNP Instructor in Surgery Research Dartmouth residents are authoring four podium and poster presentations at this year’s annual NES - American Urological Meeting. In collaboration with Dr. Bin Chen at Borwell Labs, Dr. Curtis Crane has demonstrated increased tumor vascular permeability following PDT in a rat prostate cancer model. His co-resident, Dr. Kwabana Pobi, under the direction of Dr. Merguerian, has defined the parameters for a successful hypospadias repair and presents the CHaD experience with (Deflux) in the treatment of pediatric vesicoureteral reflux. At the same meeting, recent graduate Dr. Tom Schwaab presented the DHMC experience with autologous dendritic cell vaccine in combination with immunomodulators in the treatment of metastatic RCC, work performed in conjunction with Dr. Seigne and Dr. Marc Ernstoff. Dr. Peter Steinberg, our rising research resident, is developing an efficient algorithm for the treatment of muscle invasive bladder cancer and expanding a database to assess the impact on diabetes and hyperglycemia on cystectomy outcomes. 23 Department of Surgery Sections Vascular Surgery O Jack Cronenwett, MD Section Chief Professor of Surgery and Community & Family Medicine n a national level, major changes have occurred this year in vascular surgery. Board certification no longer requires prerequisite general surgery certification, and new paradigms have been approved for training vascular surgeons without full general surgery training. We are pleased to report that our application for a new five-year vascular surgery training program was approved by the ACGME in June 2006, the first independent vascular training program to be approved in the United States. Medical students will match directly into this training program, with one resident per year. We will continue our current two-year vascular residency for training residents who have completed general surgery, such that eventually two residents will complete training each year, one from the five-year program and one from the two-year program. In the interim, we have added a third vascular resident to our current two-year program. Dr. Christopher Alessi, our 17th vascular fellow, completed training this year. He performed 178 open vascular operations and 355 interventional procedures during his two-year fellowship, including 30 carotid artery stent procedures. We were pleased to recruit Dr. Alessi to join our faculty in June. Section faculty delivered 25 international, national and regional continuing medical education presentations this year. The Section also hosted four visiting professors, including the 12th annual Rodger E. Weismann Visiting Professor. Vascular Surgery conferences are held each Monday from 7-11 am when faculty and trainees have protected time to attend. They include a bi-weekly clinical conference at which interesting patients are discussed, a bi-weekly Clinical Didactic Conference, a bi-weekly Morbidity & Mortality conference, a bi-weekly Research Conference, and a weekly pre-operative conference to discuss procedures to be performed that week. Vascular Journal Club is held twice per month to review contemporary articles of interest, and a Basic Science Conference and Vascular Laboratory Conference are held monthly. Interested clinicians are welcome to attend these conferences. Research The vascular biology research laboratory continues to focus on smooth muscle cell biology, investigating the molecular regulation of events leading to smooth muscle proliferation. Dr. Richard Powell and Dr. Eva Rzucidlo have NIH funding for this research. Dr. Rzucidlo received new funding this year from Pfizer to investigate the impact of statins in this area. Translational research concerning gene therapy using hepatic growth factor to stimulate lower extremity Vascular Surgery Gross Revenue (in millions) 20M 18M 16M 14M 12M 10M 8M 6M 4M 2M 3,000 2,700 2,400 2,100 1,800 1,500 1,200 900 600 300 FY01 24 Vascular Surgery Cases FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report angiogenesis has been initiated by Dr. Powell. Dr. Mark Fillinger is the national principal investigator for both the Gore low permeability and Pythagoras endoprosthesis trials for AAA repair, and continues to serve as the local principal investigator for seven endovascular AAA research protocols. He has initiated an international study to predict AAA rupture risk based on wall stress measurement using 3-D CT data, with over 200 patients entered worldwide. Dr. Powell is the local principal investigator for 5 carotid artery stent trials. The Vascular Study Group of Northern New England continues to accrue registry data from hospitals in Maine, New Hampshire and Vermont, now with more than 5,000 vascular surgery operations analyzed to provide hospital-specific feedback for improving outcomes. Research activity resulted in 22 peer-reviewed journal articles and 8 book chapters published by the faculty this year, in addition to 14 presentations at surgical society meetings. Section faculty participated in 28 external research grants and contracts this year. Patient Care Reflecting national trends, the volume of open vascular operations remained stable, while interventional and endovascular procedures continued to increase this year. Under the direction of Dr. Fillinger, thoracic endovascular procedures have been successfully introduced with more than 30 procedures performed for aortic aneurysm and dissection. Retrograde stenting of the superior mesenteric artery during open operation for acute mesenteric ischemia has been invented by Section faculty and introduced nationally in a presentation by Dr. Mark Wyers. Carotid artery stenting has been fully integrated into our clinical practice, with more than 200 procedures having been performed. Faculty Activity Section faculty continued to be extensively involved in national and www.dhmc.org/goto/surgery_annual_report Vascular Surgery Christopher Alessi, MD Assistant Professor of Surgery Mark Fillinger, MD Professor of Surgery Brian Nolan, MD Assistant Professor of Surgery Richard Powell, MD Professor of Surgery and Radiology Eva Rzucidlo, MD Assistant Professor of Surgery Daniel Walsh, MD Professor of Surgery Mark Wyers, MD Assistant Professor of Surgery Robert Zwolak, MD, PhD Professor of Surgery regional vascular societies where they hold 15 officer or committee roles, in addition to 4 positions on the editorial boards of peer-reviewed journals. Dr. Jack Cronenwett was elected President of the Association of Chairs in Vascular Surgery and was named an honorary member of the Society for Clinical Vascular Surgery. Dr. Daniel Walsh was elected to the Executive Council of the Vermont Medical Society. Dr. Robert Zwolak was elected Treasurer of the Society for Vascular Surgery. Dr. Fillinger was promoted to Professor of Surgery. Dr. Powell chaired the Research Council of the Society for Vascular Surgery and the Program Committee of the New England Society for Vascular Surgery. Dr. Rzucidlo was elected to membership in the American College of Surgeons. Dr. Wyers was appointed medical co-director of the DHMC noninvasive vascular laboratory and elected to membership in the American College of Surgeons. Dr. Brian Nolan received the Alma Hass Milham Endowment Scholarship to allow enrollment in the masters program at the Center for the Evaluative Clinical Sciences. Vascular Research Lab Mary Jo Mulligan-Kehoe, PhD Research Associate Professor of Surgery Kathleen Ann Martin, PhD Research Assistant Professor of Surgery 25 Department of Surgery Sections Maxillofacial Surgery O ral and Maxillofacial Surgery provides a wide array of care, from primary to tertiary levels. Complex cases involving pathology and structural deformities of the maxillofacial region are referred to Dartmouth-Hitchcock from the tri-state area. Dr. Rocco Addante remains active academically as a journal reviewer for articles submitted for publication to the Journal of Oral and Maxillofacial Surgery and Oral Medicine, the Journal of Oral Surgery and the Journal of Oral Pathology. In addition, he has two chapters slated for publication this fall – one in the Oral and Maxillofacial Surgery Clinics of North America (Verrucous Carcinoma of the Oral Cavity) and one in Oral and Maxillofacial Surgery Knowledge Update, Volume IV (The Comprehensive Evaluation of the Oral Tumor Patient). He continues to mentor students from Dartmouth with an interest in careers combining medicine and dentistry. DHMC provides comprehensive care in several interdisciplinary clinics and Dr. Addante plays an active role in Rocco Addante, MD, DMD Section Chief Professor of Surgery and Anesthesiology Maxillofacial Surgery Gross Revenue (in thousands) 1,800K 1,620K 1,440K 1,260K 1,080K 900K 720K 540K 360K 180K Maxillofacial Surgery Cases 350 315 280 245 210 175 140 105 70 35 FY01 26 the Craniofacial Anomalies Clinic and Head and Neck Cancer. In addition, Dr. Addante provides care for patients from the Hematology Oncology Service, who typically exhibit coagulation disorders and immune suppression along with their need for oral surgery. Locally, Dr. Addante hosts monthly meetings for the hospital dental staff and provides periodic lectures to the dental community on topics of mutual interest. On the national level, he has completed his term as chairman of the Commission on Ethics and Professional Conduct of the American Association of Oral and Maxillofacial Surgeons, but he continues to serve on the commission. He also serves as regional consultant to the American Board of Oral and Maxillofacial Surgery. Although there is no residency in Maxillofacial Surgery at DHMC, Dr. Addante maintains close affiliations with the Sections of Plastic Surgery and Reconstructive Surgery and is a valued contributor to the resident teaching program in that specialty. FY02 FY03 FY04 FY05 FY06 FY01 FY02 FY03 FY04 FY05 FY06 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Program Highlights Thoracic Surgery Program O ver the past year, general thoracic surgery at DHMC has continued to flourish, building upon the trend of the previous two years. Most initiatives described a year ago have developed and matured. Surgical volume continues to increase over the previous year, and now includes an increasing number of esophageal cases (benign and malignant). Having two surgeons, Dr. David Johnstone and Dr. William Nugent, dedicated to thoracic surgery, has been a critical factor, allowing the nursing and paraprofessional staff to gain experience and expertise in the care of these patients. We are now entering our third year with PGY-4 housestaff rotating as the senior thoracic resident. The residents now regard this rotation as one of their best “operating” rotations and have provided outstanding patient care as well as leadership of the junior cardiothoracic housestaff. The Section provides regular didactic sessions covering topics in cardiac and thoracic surgery. We continue to develop a more robust thoracic curriculum. Endobronchial therapy (laser, stents, brachytherapy) is now routinely available in the OR or Endoscopy Suite. This service has matured under the leadership of Dr. Johnstone and Dr. DeLong of Pulmonary Medicine, who have worked to provide seamless coverage and useful collaboration in this challenging population of patients. www.dhmc.org/goto/surgery_annual_report Esophageal surgery, both malignant and benign, has gradually increased over the past year. We have taken on reoperative procedures for failed antireflux operations, resections for achalasia, and repair of diverticula. In conjunction with Dr. Sutton of General Surgery and members of the GI Oncology services, DHMC offers first-class treatment of cancer of the esophagus. Interest in minimally invasive approaches to this disease remains, and we hope to gradually move forward with that in the next year. Finally, the multidisciplinary thoracic oncology clinic is expected to begin this fall, with all specialties available in the same location to provide patients with efficient comprehensive lung cancer care. This is the result of a year of collaborative effort among the various sections involved and Norris Cotton Cancer Center. As the breast clinic has demonstrated, we expect the lung cancer clinic to raise regional awareness of our expertise in cancer care and research, increase patient visits, and boost surgical volume over the coming years. David W Johnstone, MD Associate Professor of Surgery 27 Program Highlights Trauma Program T John Sutton, MD, FACS Director of Trauma Services Professor of Surgery he sudden and unpredictable nature of traumatic injuries not only creates problems for patients and their families, but challenges medical care system resources as well. In order to meet this challenge, the DHMC Section of General Surgery created the Trauma and Acute Surgical Care Service in 1998. Dr. John E. Sutton, Jr., Division Chief, and the other Trauma/Consult staff attendings; Drs. Kenneth Burchard, Horace Henriques, Paul Kispert, and Rajan Gupta have dedicated interests and certification in trauma and acute surgical care. Working with the General Surgery residents and nurse practitioner, this team is focused on the prompt coordination of care for patients with multi-system trauma, critical surgical illness, and a wide variety of acute surgical problems seen at a Level I trauma center. While on service, the attending does not carry any other clinical responsibilities, which allows them to be available day or night for emergent patient care. Clinical Service The number of trauma patients admitted to DHMC has increased over 50% in the past four years. Currently, more than 1,200 patients are admitted annually. Much of this increase is a result of subspecialty unavailability at referring hospitals, requiring DHMC to play an increasing role in the care of the injured patients of Vermont and New Hampshire. To meet this demand, our in-house subspecialty services have expanded as well with the addition of specialists in Orthopedic, Spine, Pediatric Surgery, and Pediatric Neurosurgical trauma. The newest addition to the Trauma/ Consult service is Dr. Rajan Gupta. Dr. Gupta completed his Trauma/Critical Care Fellowship at the University of Pennsylvania. In addition to his clinical skills, Dr. Gupta has a particular interest in performance improvement (PI) 28 and has been appointed as the trauma program’s Performance Improvement Director. He is currently implementing a new performance improvement program that will Rajan Gupta, MD enable the trauma program to more accurately identify problems and enable us to make systems changes that will ultimately enhance care. This process is labor intensive and has required us to add a PI nurse coordinator as well as a second trauma registrar to assist in the collection and entry of important data. Education/Research Providing access to national and local trauma care experts, our annual trauma conference provides CME for local physicians, nurses, and EMS providers. The success of this conference over 15 years has enabled us to establish the Trauma Research Fund, which supports clinical investigation by DHMC staff and residents. Recently, the fund has provided support for Dr. Ian Paquette (a PGY-3) to present a retrospective study on “Hypoadrenalism in Trauma” at the American College of Surgeons Regional Residents’ Paper Competition. This work will be continued in a larger prospective study, under Dr. Burchard’s direction, to study hypoadrenalism in severely injured patients admitted to the ICU. In addition to yearly presentations at the New England Regional Trauma Conference, Dr. Sutton and Dr. Kispert have presented abstracts at the annual meeting of the New England Surgical Society. Topics have included patterns of head injury management, injury and cost associated with not wearing seatbelts, Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report and delays in transfer of trauma patients in New Hampshire. Dr. Kispert has also authored 4 chapters in “Common Errors in the ICU.” Dr. Henriques’ work on establishing a pain management protocol for trauma patients in the emergency room will soon be published in the Journal of Trauma. Trauma service education is provided by weekly trauma conferences. At these meetings, attending physicians, residents, and specialty services gather to discuss recent trauma cases, listen to didactic presentations, participate in journal club, or work with interactive DVD programs to provide trauma education. This also allows concurrent discussion of trauma system issues to provide timely intervention to improve patient care. Advanced Trauma Life Support (ATLS) courses are also given two to three times per year for residents and outside physicians. Computerized mannequins, called simulators, are currently being used in medicine to provide experience for physicians-in-training. DHMC has such a simulator which can be programmed to re-create a severely injured trauma patient arriving in the emergency room. The procedures and decision making involved in the work-up of a trauma patient can thus be practiced without harm to a real patient. The trauma program has created such an experience for residents, which has been incorporated into their education experience. Goals for the future • Develop, with the New Hampshire Division of EMS, a trauma simulator program for hospitals to teach trauma team cooperation and organization of resuscitation skills. • Increase the number of telemedicine trauma case conferences with referring hospitals. • Video record resuscitations in the Emergency Room for Performance Improvement and educational purposes. • Complete research projects: Hypoadrenalism of critical illness Trauma in the elderly Hypertonic saline during elective surgery • Further development of the multidisciplinary trauma PI program. Regional/National Activities Dr. Sutton (Chair), Dr. Gupta and Eileen Corcoran, RN, serve on the New Hampshire Trauma Medical Review Committee. This committee is responsible for the trauma system planning and development of protocols for the state of New Hampshire. Dr. Gupta represents the state of New Hampshire on the American College of Surgeons Committee on Trauma. www.dhmc.org/goto/surgery_annual_report 29 Office of Surgical Education Medical Student Education T Ken Burchard, MD Surgery Clerkship Co-Director Consult/Trauma Learning Leader Horace Henriques, MD Surgery Clerkship Co-Director General Surgery Learning Leader 30 he formal engagement of faculty and residents in the third-year clerkship Director of Learning Program has successfully reminded us that learning is a two way street. While fund of knowledge typically resides on the side of the ‘teacher,’ we are all ‘students’ in our understanding of core competencies such as communication, interpersonal skills, and professionalism. We recognize understanding concepts as a role equal to the acquisition of factual knowledge. Formalizing this learning process provides the opportunity to model the core competency of self-learning. Incorporating these core clinical competencies into the clerkship’s formal curriculum allows minimal transition in expectations as students move from their third-year clerkship into fourth-year sub-internship programs, and finally into residencies. The seven rotation options; Vascular, Trauma/Consult, Transplant/IBD, Oncology/Breast, Cardiothoracic, Minimally Invasive, and the multidisciplined (General, Vascular, Plastics, ENT, Orthopaedics) VA rotation, continue to offer a broad view of the many disciplines within surgery as well as providing students with a diversity of practice models. All students continue to participate in night call with the Trauma/Consult team. This configuration continues to have strong support and allows a reasonably balanced experience of elective and emergent surgical situations. Night call also allows students to routinely interact and experience non-core surgical disciplines such as Orthopaedics, Neurosurgery, Urology, Plastics, Ophthalmology, and Pediatrics. The Class of 2006 graduated with 18% of students entering a surgical field, above the national average of 10 to 12%. Dr. Meredith Sorensen was this year’s recipient of the Arthur Naitove Surgical Scholar Award and she will receive her training at Dartmouth. The Naitove Award commemorates one of Dartmouth’s great clinician scientists and is awarded by the Faculty of the Dept. of Surgery. Dr. Philip Goodney, a General Surgery chief resident, was this year’s recipient of the Thomas P. Almy Housestaff Teaching Award. This honor is awarded to a resident by the graduating medical school class. This year marks the third year in a row, and the eighth time in ten years, that a surgery resident has been awarded this unique honor. For additional information on the Surgery Clerkship and the Sub-Internship Program, the web page remains active and is updated regularly. Clerkship Advisory Board The Clerkship Advisory Board meets monthly and is comprised of individuals actively involved in student education. The committee conducts ongoing reviews of the curriculum, making revisions as necessary to maintain a current curriculum and advancing an educational climate. It is the forum by which the surgery clerkship formally interacts with the Dean’s Office in student and curriculum issues. Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Training Programs Research and Preventive Medicine Training Opportunities We offer research opportunities in molecular labs and outcomes research. Some residents elect to join our Leadership in Preventive Medicine Residency Program where they get formal training in outcomes research, earn an MPH, and become eligible for Preventive Medicine certification. 2005-2006 • Justin Dumouchel, MD—Vascular Research, DHMC • Lydia Choi, MD—Cancer Research, Memorial Sloan Kettering • Sarah Greer, MD—Cancer Research - National Institute of Health • David Hughes, MD—Research - DHMC • Daniel Wiener, MD—Cancer Research, Dana Farber Cancer Institute 2004-2005 • Jared Barton, MD—Leadership in Preventive Medicine • Lydia Choi, MD—Cancer Research, Memorial Sloan Kettering • Michael Van Bibber, MD—Research, Outcomes— DHMC/VAMC •Daniel Wiener, MD—Cancer Research, Dana Farber Cancer Institute 2003-2004 •Richard Kutz, MD—Research, Outcomes— DHMC/VAMC •Melissa Meyers, MD—Research, Outcomes— DHMC/VAMC •Elsa Valsdottir, MD—Research, Outcomes— DHMC/VAMC •Daniel Wiener, MD—Cancer Research, Dana Farber Cancer Institute 2002-2003 • David Brown, MD—Research, Vascular Surgery • Philip Goodney, MD—Research, Outcomes—DHMC/VAMC • Erin Rowell, MD—Research, Vascular Surgery •Brent White, MD—Research, Outcome— DHMC/VAMC Fellowship Programs: • Plastic Surgery • Vascular Surgery www.dhmc.org/goto/surgery_annual_report Training Programs Neurosurgery Vascular Urology Plastic Surgery Otolaryngology General Surgery Resident Training 2005-2006 General Surgery Established: 1946 Prerequisite Training: 4 years of medical school Description: 5-year program, training in all divisions Residents per year: 4 Neurosurgery Established: 1947 Prerequisite Training: 1 year internship Description: 6-year program includes 4 years clinical neurosurgery with 6 months of pediatric neurosurgery, 3 months neurology, 3 months of related clinical rotations in the ED and critical care; 1 year of independent research; and 1 year Chief Resident experience. Residents per year: 1 Plastic Surgery Established: 1960 Prerequisite Training: 3 years of general surgery or completion of a residency in another surgical discipline. Description: 3-year training with a period of research integrated into the program. Residents per year: 1 Urology Established: 1949 Prerequisite Training: 2 years of general surgery Description: 4 years, including 6 months of research. Training in pediatric and adult urology including oncology, laparoscopy, female urology, infertility, and endourology. Residents per year: 2 every second year—we will start 2 every year effective July 2006 31 Sponsored Research Research: Clinical Trials General Surgery Vascular Surgery John E. Sutton, Jr., MD • Laparoscopic-Assisted Colectomy Mark F. Fillinger, MD • Zenith-Protocol TX2 - Thoracic TAA • Pythagoras Study • Valor Study -Protocol • AneuRx • Cordis Endovascular Quantum LP —Protocol No P01-4601 • Edwards Lifepath AAA 2001-2002 • Gore (Modified) Bigurcated Excluder —99-04 • Gore Excluder 31mm - Protocol #AAA 03-02 • Gore04-04 Protocol #AAA 04-04 • CaridoMEMS AAA pressure sensor system Thadeus L. Trus, MD • SAGES Neurosurgery David W. Roberts, MD • Stereotactic Microscope Project Plastic Surgery E. Dale Collins, MD • Contour Profile Gel Mammary Prosthesis • Integrating Decision Support in Breast Cancer Care Carolyn L. Kerrigan, MD, MSc • CLOSEX Mitchell A. Stotland, MD • Botox Intervals R&E - MAS Urology Richard J. Powell, MD • Anges 0205 • EXACT-Protocol $640-0063-01 • VIVA Protocol #17683 • Genzyme/IMPROVE Study - Protocol #PADHIF00704 • Advance Protocol #P03-5203 Ajay K. Nangia, MB BS • BPH Registry - (Protocol #L8890) Clinical Research Neurosurgery Urology General Surgery Plastic Surgery Vascular 32 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Research: Federal & Corporate Audiology Urology Victoria Keetay, PhD • Dynamic Assessment of Hearing Aids John Heaney, MB, BCh • Prostate Cancer Prevention Trial PCPT Companion Long Term Follow Up Study for Men with Diagnosed Prostate Cancer • Selenium and Vitamin E Cancer Prevention Trial (SELECT) General Surgery Richard J. Barth, Jr, MD • ACOSOG Studies Z10 and Z11 Burton L. Eisenberg, MD • The Molecular Actions of Imatinib Mesylate in GISTs • RTOG Committee Chair Agreement Samuel Finlayson, MD • Medical and Surgical Treatment of Esophageal Reflux • Evaluating the Safety and Effectiveness of Endovascular Stent Grafts for AAA Plastic Surgery E.Dale Collins, MD • Implementing Shared Decision Making in Clinical Care Carolyn L. Kerrigan, MD, MSc • Carpal Tunnel Syndrome: Diagnosis & Treatment Study Pediatrics Ann-Christine Duhaime, MD • Trauma to the Immature Brain: Response, Repair, & Treatment • Biomechanics of Pediatric Head Trauma Vascular Surgery Federal & Corporate Research General Surgery Ophthalmology Pediatric Surgery Jack Cronenwett, MD Audiology • Northern New England Vascular surgery Quality Urology Improvement Initiative • Ultrasound Screening for Abdominal Aortic Aneurysm Surgical Res Lab Vascular Research Lab Kathleen Martin, PhD • Sub of 5-38049 • Induction of Vascular Smooth Muscle Cell Differentiation by Rapamycin Richard J. Powell, MD • Endothelial Cell Regulation of Smooth Muscle Phenotype • Carotid Revascularization Endarterectomy vs Stenting Trial (CREST) Eva M. Rzucidlo, MD • mTOR Regulation of VSMC Differentiation • Statin Effect on Vascular Smooth Muscle Cell Differentiation Through the mTOR Pathway Surgical Research Lab Jeffrey Bergeron, MD • In Vivo Feline Study • Evaluation of Prototype Electrosurgical Instruments P. Jack Hoopes, DVM, PhD • Wave Contract • GlycoFi Rituxan Project • Ethylene Vinyl Alcohol (EVOH) for Obesity Plastic Surgery Vascular Mary Jo Mulligan-Kehoe, PhD • Mechanisms of PAI-1 Induced AntiAngiogenesis • Philips Master Collaborative Research Agreement Ophthalmology Michael E. Zegans, MD • Biofilm Formation Associated with P. aeruginosa Infection of the Eye • Steroids in Corneal Ulcers Trial Grant Funding 1998 - 2006 3,500,000 3,150,000 2,800,000 2,450,000 2,100,000 1,750,000 1,400,000 1,050,000 700,000 350,000 FY98 www.dhmc.org/goto/surgery_annual_report FY99 FY00 FY01 FY02 FY03 FY04 FY05 FY06 33 Department of Surgery Awards The Arthur Naitove Distinguished Teaching Award Thadeus Trus, MD General Surgery The Arthur Naitove Distinguished Teaching Award was instituted by the residents in 1997 to recognize a faculty member’s commitment to the housestaff. The award is presented to an attending staff for their commitment to enhance the residency educational experience. The 2006 recipient was Dr. Thadeus Trus. The Harmes Surgical Scholar Award Susan R Durham, MD Pediatric Neurosurgery The Harmes Surgical Scholar Award is awarded annually to a faculty member at the Assistant or Associate Professor level in the Department of Surgery. The annual financial award is provided over three years to facilitate career development by strengthening individual professional skills; enhancing contributions to the academic, clinical, and administrative programs of the Department; improvising the regional and national visibility of DHMC; and increasing each individual’s sense of professional competence and satisfaction. The Harmes Scholar named for 2006 was Dr. Susan Durham. Invited Speakers The New Face of War, Combat Casualties from the Global War on Terrorism. Raymond Harshbarger, MD, MAJ, MC, Director of Left Craniofacial Surgery, Walter Reed Army Medical Center Cardiac Risk in Vascular Surgery: Current Evaluation and Management. William Mackey, MD, New England Medical Center, Surgeon-in-Chief, Tufts New England Medical Center, Chair, Department of Surgery, Tufts University School of Medicine Bedside to Bench: Translational Research in Vein Graft Disease. Michael Conte, MD, Division of Vascular Surgery, Brigham & Women’s Hospital Carotid Endarterectomy in the Endovascular Era. Bruce Perler, MD, Julius H. Jacobson II Professor of Surgery, The Johns Hopkins University School of Medicine Medicine, Money and Manpower: Are we approaching the Perfect Storm? Pardon Kenney, MD, Professor of Surgery, Chief of Surgery, The Faulkner Hospital Transition to Molecular Triage for the Treatment of Breast Cancer: The ISPY Trial. Laura Esserman, MD, Professor of Surgery and Radiology, University of California, San Francisco Learning to Operate: From Lab Coats to Arm Chairs to Simulators. Gerald M. Fried, MD, Professor of Surgery and Adair Chair of Surgical Education, McGill University A Surgical Conundrum: Malignant Bowel Obstruction. Robert Krouse, MD, FACS, University of Arizona The Surgical Chair’s Award Thomas Colacchio, MD On the clinical front, the Department has continued to highlight the quality of patient care. In 2005, Dr. Thomas Colacchio was selected to receive the Surgical Chair’s Award for his ongoing contributions to the Department, his emphasis on patient care and his focus on quality throughout the organization. General Surgery President, DartmouthHitchcock Clinic 34 Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Department of Surgery Publications: 2006 Cardiothoracic Surgery Lawrence J. Dacey, MD Dacey LJ, Likosky DS, Charlesworth DC, Leavitt BJ, Lahey SJ, Quinn RD, Hernandez F, Quinton HB, O’Connor GT: Perioperative stroke and long-term survival after coronary bypass surgery. Annals of Thoracic Surgery 2005; 70:532-6. Malenka DJ, Leavitt BJ, Hearne MJ, Robb JF, Baribeau YR, Ryan TJ, Helm RE, Kellett MA, Dauerman HL, Dacey LJ, Silver MT, VerLee PN, Weldner PW, Hettleman BD, Olmstead EM, Piper WD, O’Connor GT. Comparing Long-term Survival of Patients With Multivessel Coronary Disease After CABG or PCI: Analysis of BARI-like Patients in Northern New England. Circulation 2005; 112(9 Suppl):I371-6. Dacey LJ, Johnstone DW. Reducing the Risk of Lung Cancer. (Editorial) JAMA 2005 28;294(12): 1550-1. Baskett RJ, O’Connor GT, Hirsch GM, Ghali WA, Sabadosa KA, Morton JR, Ross CS, Hernandez F, Nugent WC, Lahey SJ, Sisto D, Dacey LJ, Klemperer JD, Helm RE, Maitland A. The Preoperative Intraaortic Balloon Pump in Coronary Bypass Surgery: A Lack of Evidence of Effectiveness. Am Heart J 2005; 150(6):1122-7. Anthony DiScipio, MD DiScipio AW, Shemin RJ. Acquired Cardiac Disease. Essentials of Surgery, ed.Becker, (citation info not available). Yeager MP, Rassias AJ, Fillinger MP, Discipio AW, Gloor KE, Gregory JA, Guyre PM. Cortisol antiinflammatory effects are maximal at postoperative plasma concentrations. Crit Care Med. 2005 Jul; 33(7):1507-12. David Johnstone, MD Chang JY, Moughan J, Johnstone D, et al. Surgical patterns of care in operable lung carcinoma treated with radiation. Submitted to J Thorac Oncol 2006 Johnstone DW. Modified intrapleural cisplatin treatment for lung cancer with positive pleural lavage cytology or malignant effusion. (Editorial) J Surg Oncol 2006; 93:255-256. Dacey LJ, Johnstone DW. Reducing the risk of lung cancer. (Editorial) JAMA 2005; 294:1550-1. Y. Chen, K. J. Pandya, T. Smudzin, R. Qazi, B. D. Smith, O. Hyrien, DW Johnstone, et al. Phase II study of induction docetaxel/cisplatin with rhG-CSF followed by concurrent pulsed docetaxel chemoradiation for stage III non-small cell lung cancer (NSCLC). J Clin Oncol 2006; ASCO Proceedings 24 (18S): 17034 Strauss GM, Herndon JE, Maddaus MA, Johnstone DW, et al. Adjuvant chemotherapy in stage IB nonsmall cell lung cancer (NSCLC): Update of Cancer and Leukemia Group B (CALGB) protocol 9633. J Clin Oncol 2006; ASCO Proceedings 24 (18S): 7007. www.dhmc.org/goto/surgery_annual_report William C. Nugent, Jr., MD Baskett RJ, O’Connor GT, Ross CS, Sabadosa KA, Dacey LJ, Hernandez F, Lahey SJ, Nugent WC, Sisto D,Klemperer J, Helm RE. The Preoperative intraaortic balloon pump in Coronary Artery Bypass Surgery: A lack of evidence of effectiveness. American Heart Journal, December 2005; 150(6):1122-1127 Surgenor SD, DeFoe GR, Leavitt BJ, Likosky DS, Helm RE, Groom RC, Fillinger MP, Klemperer JD, Krumholz CF, Westbrook BM, Clark C, Galatis DJ, Frumiento C, Ross CS, Olmstead EM, O’Connor GT. Risk of low output heart failure is associated with treatment of hemodilutional anemia by red blood cell transfusion during coronary artery bypass graft surgery. Circulation Supplement. (in press) Likosky DS, Nugent WC, Ross CS. Improving Outcomes of Cardiac Surgery Through Cooperative Efforts: The Northern New England Experience. Seminars in Cardiothoracic and Vascular Anesthesia, June 2005; 9:2:119-121. Likosky DS. A Primer on Reviewing and Synthesizing Evidence. Journal of Extracorporeal Technology. (in press) Likosky DS, Nugent WC, OConnor GT. A Comparison of Three Measurements of Cardiac Surgery Mortality for the Northern New England Cardiovascular Disease Study Group. Ann Thorac Surg 2006; 81:1393-5. Department of Surgery Donald S Likosky, PhD Dacey LJ, Likosky DS, Leavitt BJ, Lahey SJ, Quinn RD, Hernandez F, Quinton HB, DeSimone JP, Ross CS, O’Connor GT. Perioperative Stroke and LongTerm Survival After Coronary Bypass Surgery. Annals of Thoracic Surgery 2005; 79: 532-7. Likosky DS, Nugent WC, Ross CS. Improving Outcomes of Cardiac Surgery Through Cooperative Efforts The Northern New England Experience. Seminars in Cardiothoracic and Vascular Anesthesia 2005; 9: 119-21. Nelson EC, Homa K, Mastanduno M, Fisher E, Batalden PB, Colacchio T, Formella N, Foster TC, Likosky DS, Gardent PB, Guth J, Malcolm E, Trombly S, Varnum J. A Healthcare System’s Experience with Publicly Reporting Comprehensive Quality and Cost Data: A Transparency Initiative. Joint Commission Journal on Quality and Patient Safety 2005; 31: 573-84. Likosky DS, Donegan DJ, Groom RC, Buchanan SA, Morton JR, Ross CS, O’Connor GT. Embolic activity subsequent to injection of the internal mammary artery with papaverine hydrochloride. Heart Surgery Forum 2005; 8: E434-6. Likosky DS, Nugent WC, Clough RA, Weldner PW, Quinton HB, Ross CS, O’Connor, GT. A Comparison of Three Measurements of Cardiac Surgery Mortality. Annals of Thoracic Surgery 2006; 81: 1393-5. Likosky DS. A Primer on Randomized Clinical Trials. Journal of Extracorporeal Technology 2006; 38: 10-13. Shann KG, Likosky DS, Murkin JM, Baker RA, Baribeau YR, DeFoe GR, Dickinson TA, Gardner TJ, Grocott HP, O’Connor GT, Rosinski DJ, Sellke FW, Willcox TW. An Evidence-Based Review of the Practice of Cardiopulmonary Bypass in Adults. Journal of Thoracic & Cardiovascular Surgery. (in press) General Surgery Kenneth Burchard, MD Rowland PA, Coe NPW, Burchard KW, Pricolo VE. Factors affecting the professional image of physicians. Curr Surg 2005; 62:214-219. Burchard KW, Rowland PA, Berman NB, Hanissian PD, Carney PA. Clerkship Enhancement of Interpersonal Skills. The American Journal of Surgery 189:643-646, 2005. Burton L. Eisenberg, MD Mullenix PS, Brown, TA, Meyers MO, Giles LR, Sigurdson ER, Boraas MC, Hoffman JP, Eisenberg BL, Torosian MH. The association of cytokeratinonly-positive sentinel lymphnodes and subsequent metastases in breast cancer. Am J Surg 189(5):606-609; discussion 609, 2005. Tarn C, Merkel E, Canutescu AA, Shen W, Skorobogarko Y, Heslin MH, Eisenberg B, Birbe R, Patchefsky A, Dunbrack R, Arnoletti JP, Mehren MV, Goodwin AK. Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling. Clin Cancer Res 11(10):3668-3677, 2005. Eisenberg BL. Soft tissue sarcomas: opportunities for defining the molecular phenotype of a solid tumor malignancy. Curr Opin Oncol 17(4):355-356, 2005. Blanke C, Eisenberg BL, Heinrich Ml. Epidemiology of GIST. Am J Gastroenterol 100(10):2366, 2006. Benjamin RS, Blanke CD, Blay JY, Bonvalot S, Eisenberg B. Management of gastrointestinal stromal tumors in the imatinib era: selected case studies. Oncologist 11(1):9-20, 2006. Kraybill WG, Harris J, Spiro IJ, Ettinger DS, DeLaney TF, Blum RH, Lucas DR, Harmon DC, Letson GD, Eisenberg B. Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514. J Clin Oncol 24(4)619-625, 2006. Tarn C, Skorobogatko YV, Taguchi T, Eisenberg B, Mehren MV, Godwin AK. Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. Cancer Res 66(10):5477-5486, 2006. 35 Department of Surgery Publications: 2006 Samuel R. Finlayson, MD Trus TL, Pope GD, Finlayson SRG. National trends in utilization and outcomes of bariatric surgery. Surg Endosc; 5:616-620, 2005. Gupta R, Carpenter J. Surveillance of Deep Venous Thrombosis. In: Frankel H. (ed): Ultrasound for Surgeons. Georgetown, TX: Landes Bioscience, 78-83, 2005. Pohl H, Finlayson SRG, Sonnenberg A, Robertson, DJ. Helicobacter pylori-associated ulcer bleeding: Should we test for eradication after treatment? Aliment Pharmacol Ther. 2005; 22(6):529-537. Mancini DJ, Gupta R. Acute Mesenteric Ischemia. In: Marcucci L, Martinez E, Haut E, et al. (eds) Avoiding Common ICU Errors. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. (in press) Finlayson SRG. Surgery in rural America. Surg Innov; 2005:12. Mancini DJ, Gupta R. Corticosteroids in the ICU. In: Marcucci L, Martinez E, Haut E, et al. (eds) Avoiding Common ICU Errors. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. (in press) Dimick JB, Finlayson SRG. Rural hospitals and volume standards in surgery. Surgery. (in press) Finlayson SRG. Volume-outcome revisited. Am Surg (in press) Chappel AR, Zuckerman RS, Finlayson SRG. Small rural hospitals and high-risk surgery: How would regionalization affect surgical volume and hospital revenue? J Am Coll Surg (in press) Doty B, Heneghan S, Gold M, Bordley J, Dietz P, Finlayson SRG, Zuckerman RA. Is a broadly based surgical residency program more likely to place graduates in rural practice? World J Surg (in press) VanBibber M, Zuckerman RA, Finalyson SRG. Rural vs. Urban in-patient care-mix differences in the United States. J Am Coll Surg (in press) Finlayson SRG. Evidence-based Surgery in Souba W et al. (ed) ACS Surgery: Principles and Practice, New York: WebMD Professional Publishing, 2006 (in press) Rajan Gupta, MD Brady KA, Berry S, Gupta R, Weiner M, Turner BJ. Seasonal variation in undiagnosed HIV infection on the general medicine and trauma services of two urban hospitals. JGIM 20:1-7, 2005. Reilly PM, Schwab CW, Kauder DR, Dabrowski GP, Gracias VH, Gupta R, Pryor JP, Braslow B, Kim P, Wiebe DJ. The invisible trauma patient: emergency department discharges. J Trauma 58(4):675-85, 2005. Mancini DJ, Gupta R. Chylothorax & Chylous Ascites. In: Marcucci L, Martinez E, Haut E, et al. (eds) Avoiding Common ICU Errors. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. (in press) Mancini DJ, Gupta R. Glasgow Coma Score (GSC) in the ICU. In: Marcucci L, Martinez E, Haut E, et al. (eds) Avoiding Common ICU Errors. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. (in press) Horace Henriques, MD Curtis KM, Henriques HF, Fanciullo G, Reynolds CM, Suber F. Fentanyl based Pain Management Protocol provides a Safe and Effective Method to reduce time to analgesia among adult trauma patients. Journal of Trauma, accepted April 2006. Erkmen K, Al-Mefty O. Diagnosis and Treatment of Atypical and Anaplastic Meningiomas: A Review. Neurosurgery 57:538-550, 2005. Erkmen K, Al-Mefty O. Review, Use of Ultrasonic Aspiration for Dural Opening in Cranial Reoperations: Technical Note. Neurosurgery 57(1) Operative Neurosurgery Supplement 1:E216, July 2005. Erkmen K, Al-Mefty O. Review, Transcranial Resection of Olfactory Neuroblastoma. Skull Base: An Interdisciplinary Approach. Volume 15, Number 3, 2005. John Sutton Jr., MD Pipas, J M, Barth R, Zaki B, Meyer L, Bettman M, Colacchio T, Gordon S, Sutton J, Perez R, Cates J, Lewis N, McDonnell C, Cole B. Docetaxel/ Gemcitabine followed by Gemcitabine and Radiotherapy in Patients with Pancreatic Adenocarcinoma. Ann of Surg Onc accepted 2006. Erkmen K, Al-Mefty O. Review, Surgical Management of Petroclival Chordomas: Report of Eight Cases. Skull Base: An Interdiciplinary Approach. Volume 16, Number 2, 2006. Maxillofacial Surgery Gupta R, Gracias VH. Sepsis in trauma. Panam J Trauma, 2006. (in press) Addante R. Verrucous Carcinoma. Oral & Maxillofacial Clinics of North America, Vol. 18, #4, 2006. 36 Kadir Erkmen, MD Erkmen K, Pravdenkova S, Al-Mefty O. Surgical management of petroclival meningiomas: factors determining the choice of approach. Neurosurg Focus. 2005 Aug 15;19(2):E7. Erkmen K, Al-Mefty O. Review, Clinicoradiological and Surgical Considerations in the Treatment of Cholesterol Granuloma of the Petrous Pyramid. Skull Base: An Intercisciplinary Approach. Volume 15, Number 4, 2005. Rocco Addante, MD, DMD Addante R. Comprehensive Evaluation of the Oral & Maxillofacial Tumor Patient. Oral & Maxillofacial Surgery Knowledge Update, Volume #4, section: Pathology and Oncology, 2006. Gracias VH, Sicoutris CP, Meredith DM, Horan AD, Gupta R, Haut ER, Auerbach S, Sonnad S, Hanson CW, Schwab CW. Critical care nurse practitioners improve compliance with clinical practice guidelines in a “semi-closed” surgical intensive care unit. (Submitted) CCM, 2006. Morone MA, Ball PA. Spinal Traction. In Benzel EC (ed): Spine Surgery: Techniques, Complication Avoidance, and Management. Vol.2. Second Edition. Philadelphia: Elsevier Churchill Livingstone, 2005. Burchard K, Henriques HF, Walsh D, Ludington, D, Rowland P, Likosky D. Is it Live or is it Memorex? Student oral examinations and the use of video for additional scoring. American Journal of Surgery accepted June 2006. Cotton BA, Gracias VH, Insko EK, Gupta R, Born C, Schwab CW. The use of goniometry to predict inadequate flexion-extension radiographs: A preliminary study. J Trauma 59(2):396-401, 2005. Gracias VH, Horan AD, Kim PK, Puri NK, Gupta R, Gallagher JJ, Sicoutris CP, Hanson CW, Schwab CW. Digital output pulmonary artery catheters eliminate inter-operator variability and improve consistency of treatment decisions. (Submitted) Chest, 2006 Rosner MJ, Halliday AL, Ball PA. Medical Management of the Patient with Spinal Cord Injury. In Benzel EC (ed): Spine Surgery: Techniques, Complication Avoidance, and Management. Vol.2. Second Edition. Philadelphia: Elsevier Churchill Livingstone, 2005. Neurosurgery Perry A. Ball, MD Loyd RD, Ball PA, Fanciullo, GJ. Surgical procedures for intractable cancer pain. Techniques in Regional Anesthesia & Pain Management 9:167-176, 2005. Steinmetz MP, McCormick WE, Valadka A, Ball PA, Yazbak PA, Benzel EC. Penetrating Spinal Cord Injuries. In Benzel EC (ed): Spine Surgery: Techniques, Complication Avoidance, and Management. Vol.2. Second Edition. Philadephia: Elsevier Churchill Livingstone, 2005. Erkmen K, Al-Mefty O. Review, Combined Anterior and Anterolateral Approaches to the Cranial Base: Complication Analysis, Avoidance, and Management. Neurosurgery 58(4) Operative Neurosurgery Supplement 2:ONS-327-ONS-337, April 2006. David W. Roberts, MD Sun H, Roberts DW, Farid H, Wu Z, Hartov A, Paulsen KD. Cortical surface tracking using a stereoscopic operating microscope. Neurosurgery, 56 [ONS Suppl 1]: ONS-86-ONS-97, 2005. Lunn KE, Paulsen KD, Lynch DR, Roberts DW, Kennedy FE, Hartov A. Assimilating intraoperative data with brain shift modeling using the adjoint equations. Med Imag Anal 9:281-293, 2005. Lee KH, Hitti FL, Shalinsky MH, Kim U, Leiter JC, Roberts DW. Abolition of spindle oscillations and 3-Hz absence seizurelike activity in the thalamus by using high-frequency stimulation: potential mechanism of action. J Neurosurg 103:538-545, 2005. Sun H, Paulsen KD, Lunn KE, Farid H, Roberts DW, Wu Z, Hartov A. Stereopsis-guided brain shift compensation. IEEE Transactions Medical Imaging 24:1039-1052, 2005. Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Department of Surgery Publications: 2006 Whedon J, Quebada PB, Roberts DW. Spinal epidural hematoma following spinal manipulative therapy: Case report and review of the literature. J Manipulative and Physiological Therapeutics (in press). Lee KH, Blaha CD, Harris BT, Cooper S, Hitti FL, Leiter JC, Roberts DW, Kim U. Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: Potential mechanism of action in Parkinson’s disease. European J Neuroscience 23:1005-1014, 2006. Lollis SS, Weider DJ, Phillips JM, Roberts DW. Ventriculoperitoneal shunting for the treatment of refractory perilymphatic fistula. J Neurosurg 105:15, 2006. (in press) Roberts DW. The principles and applications of stereotactic neurosurgery and frameless neuronavigation. In Latchaw RE, Kucharczyk J, Moseley ME (eds): Imaging of the Nervous System, Diagnostic and Therapeutic Applications, Vol. 2. Philadelphia: Elsevier Mosby, 2005, pp 1357-1366. Lee KH, Harris B, Roberts DW. Frame-based stereotactic brain biopsy. In Schmidek HH, Roberts DW (eds): Operative Neurosurgical Techniques: Indications, Methods, and Results, 5th Edition, in two volumes. Philadelphia, PA: W.B. Saunders 2005, pp 625-638. Roberts DW: Section of the corpus callosum for epilepsy. In Schmidek HH, Roberts DW (eds): Operative Neurosurgical Techniques: Indications, Methods, and Results, 5th Edition, in two volumes. Philadelphia, PA: W.B. Saunders 2005, pp 1413-1421. Roberts DW. Comment (on Oiwa Y, Nakai K, Itakura T: Histological effects of intraputaminal infusion of glial cell line-derived neurotrophic factor in Parkinson disease model Macaque monkeys. Neurol Med Chir (Tokyo) 46:267276, 2006). Neurol Med Chir (Tokyo) 46:276, 2006. Joseph Paydarfar, MD Paydarfar JA and Likosky DS. Organ preservation and wound complications after salvage head and neck surgery: Survey results of the membership of the American Head and Neck Society. In preparation. Roberts DW. Comment (on Sinha TK, Miga MI, Cash DM, Weil RJ: Intraoperative cortical surface characterization using laser range scanning: Preliminary results. Neurosurgery, in press). Neurosurgery (in press). Black C, Zarovnaya E, Marotti J, Paydarfar J. Frozen section evaluation of head and neck margins. Modern Pathology. 2006; 19: 204A-204A 949 Suppl. 1. Roberts DW. Comment (on Campero A, Troccoli G, Martins C, Fernandez-Miranda JC, Yasuda A, Rhoton AL: Microsurgical approaches to the medial temporal region: An anatomical study. Neurosurgery, in press.) Neurosurgery (in press). Roberts DW. Editorial, Fleet street redux. Stereotact Funct Neurosurg 84, 2006. (on-line & in press) Nathan E. Simmons, MD Simmons NE. Surgical techniques in the management of thoracic disc herniations. In Schmidek HH, Roberts DW (eds): Operative Neurosurgical Techniques: Indications, Methods, and Results, 5th Edition, in two volumes. Philadelphia, PA: W.B. Saunders 2005, pp 2007-2016. Ophthalmology Michael E. Zegans, MD Zegans ME, Shanks RMQ, O’Toole GA. Bacterial Biofilms and Ocular Infections. The Ocular Surface, April 2005 3(2):12-19. Roberts DW, Darcey TM. Applications in epilepsy surgery. In Barnett GH, Maciunas RJ, Roberts DW (eds): Computer-Assisted Neurosurgery, 2nd ed. (in press) Yang, P, Zegans ME. Immune Reconstitution Uveitis. Specialty Clinical Update, http://www.aao. org/vp/edu/uveitis/v1m2, American Academy of Ophthalmology August, 2005. Roberts DW. Fundamentals of registration. In Barnett GH, Maciunas RJ, Roberts DW (eds): Computer-Assisted Neurosurgery, 2nd ed. (in press) Toutain CM, Zegans, ME, O’Toole GA. Evidence for Two Flagellar Stators and Their Role in the Motility of Pseudomonas aerugniosa. J. Bact. January 2005: 187(2); 771-777. Roberts DW. Corpus callosotomy. In Engel Jr J, Pedley TA (eds): Epilepsy: A Comprehensive Textbook, 2nd Edition. Philadelphia, Lippincott Williams & Wilkins. (in press) Barnett GH, Maciunas RJ, Roberts DW (eds): Computer-Assisted Neurosurgery, 2nd Edition. New York, NY: Marcel Dekker Publishers/Taylor & Francis Group, November, 2005. Shanks RM, Donegan NP, Graber ML, Buckingham SA, Zegans ME, Cheung AL, and O’Toole GA. Heparin stimulates S. aureus biofilm formation. Infection and Immunity, August 2005 73(8); 45964606. Otolaryngology Schmidek HH, Roberts DW (eds). Operative Neurosurgical Techniques: Indications, Methods, and Results, 5th Edition, in two volumes. Philadelphia, PA: W.B. Saunders 2005. Louise Davies, MD Davies L, Welch HG. Increasing Incidence of Thyroid Cancer in the US: 1973-2002. JAMA. 2006 295(18). Roberts DW. Editorial, Deep brain stimulation. J Neurosurg 103:399, 2005. Davies L, Welch HG. Trends in the Epidemiology of Head and Neck Cancer in the U.S. OtolaryngologyHead and Neck Surgery. In press. Roberts DW. Comment (on Fujita Y, Muragaki Y, Nambu K, Hori T, Iseki H: Three-way bipolar forceps: A novel bipolar coagulator system for nerve stimulation and detection of nerve potentials. Neurol Med Chir (Tokyo) 46:169-175, 2006). Neurol Med Chir (Tokyo) 46:175, 2006. Davies L, Hardin NJ, Beatty BG. Ki-67: Can it predict recurrence for early tongue squamous cell carcinoma? Annals of Otology, Rhinology and Laryngology 2006 115(1). www.dhmc.org/goto/surgery_annual_report Paydarfar JA, Birkmeyer NJ. Complications in head and neck surgery: A meta-analysis of postlaryngectomy pharyngocutaneous fistula. Arch Otolaryngol Head Neck Surg. 2006;132:1-6. Pediatric Surgery Daniel Croitoru, MD Lawson ML, Mellins RB, Tabangin MT, Kelly Jr RE, Croitoru DP, Goretsky MJ, Nuss D. Impact of pectus excavatum on pulmonary function before and after repair with the Nuss procedure. Presented at the American Pediatric Surgical Association Meeting May 2004. J Pediatr Surg 2005 40:174-180. Croitoru DP, Kelly Jr RE, Goretsky M, Gustin T, Keever R, Nuss D. The Minimally Invasive Nuss Technique for Recurrent or Failed Pectus Excavatum Repair in 50 Patients. Presented at the American Pediatric Surgical Association Meeting May 2004. J Pediatr Surg 2005 40:181-187. Coates EW, Karlowicz MG, Croitoru DP, Buescher ES. Distinctive Distribution of Pathogens Associated with Peritonitis in Neonates with Focal Intestinal Perforation Compared with Necrotizing Enterocolitis. Pediatrics 2005 116:e241-246. Ann-Christine Duhaime, MD Duhaime AC. When Should I Suspect Child Abuse in Head-Injured Children? In: Neurotrauma: Evidence-Based Answers to Common questions. Valadka AB, Editor. Thieme Publishers, New York, 2005, 184-189. Duhaime AC. Non-Accidental Head Injuries. In: Albright L, Ed., Principles and Practice of Pediatric Neurosurgery, Thieme Medical Publishers, 2006. (in press) Duhaime AC. Craniopharyngiomas: A Decade Later. In: Schmidek H and Roberts D, Eds. Operative Neurosurgical Techniques, 5th Edition. Elsevier, Philadelphia, 2006, 433-436. Gilles EE, Duhaime AC. Inflicted childhood neurotrauma. In: Swaiman, Ashwal, and Ferriero, Eds., Pediatric Neurology, Elsevier, Philadelphia, 2006, 1445-1470. Duhaime AC. Evaluation and management of shunt infections in children with hydrocephalus (review). Clinical Pediatrics 2006. (in press) Judkins ER, Porter B, Cook N, Clancy RR, Duhaime AC, Golden JA. Dystrophic neuritic processes in epileptic cortex. Epilepsy Research, April 2006. 37 Department of Surgery Publications: 2006 Lollis SS, Hug EB, Gladstone DJ, Chaffee S, Duhaime AC. Acquired Chiari I malformation after fractionated radiation therapy to the anterior skull base in a 20 month old boy. J Neurosurgery 104(2 Suppl):133-137, Feb 2006. Duhaime AC, Saykin AJ, McDonald BC, Dodge CP, Eskey CJ, Darcey TM, Grate LL, Tomashosky P. Functional magnetic resonance imaging of the primary somatosensory cortex in piglets. J Neurosurgery (4 Suppl Pediatrics) 104:259-264, April 2006. Duhaime AC. Large animal models of traumatic injury to the immature brain. Developmental Neuroscience, 2006. (in press) Durham SR, Duhaime AC. Maturation-dependent response of the immature brain to experimental subdural hematoma. Journal of Neurotrauma 2006. (in press) Susan Durham, MD Selden N, Durham S, Anderson G, Braner D. Intracranial navigation using a novel device for endoscope fixation and targeting: Technical innovation. Pediatric Neurosurg 41:233-236, 2005. Durham S, Duhaime AC. Maturation-dependent response of the immature brain to experimental subdural hematoma. J Neurotrauma, in press. Durham S, Liu K, Selden N. Utility of serial computed tomography in pediatric head trauma, J Neurosurgery, in review. Durham S. Huang J. Surgical Management of Sciatic Nerve Lesions. In Operative Neurosurgical Techniques: Indications, Methods and Results, 5th ed. Schmidek and Sweet, eds. Saunders, Philadelphia, PA, 2005. Plastic Surgery Hegel M, Collins E, Kearing S, Gillock K, Moore C, Ahles T. Sensitivity and Specificity of the Distress Thermometer for Depression in Recently Diagnosed Breast Cancer Patients. Manuscript in Preparation. Carolyn Kerrigan, MDCM, MSc Kerrigan CL, Discussion: Prospective Study of Outcomes after Reduction Mammaplasty. Plast Recon Surg, 2005. 115(4): p. 1032-1033. Cunningham BL, Gear AJL, Kerrigan CL, Collins ED. Analysis of Breast Reduction Complications Derived From The Bravo Study. Plast Recon Surg, 2005. 115(6): p. 1597-1604. Joseph Rosen, MD Rosen Joseph, Koop J. Everett, Grigg Elliott: The Biological Disaster Challenge. Journal of Emergency Management, January/February 2005 or March/April 2006 Mitchell Stotland, MD, CM Ouhilal, S, Turco J, Nangia A, Stotland MA, and Manganiello PD, True hermaphroditism presenting as bilateral gynecomastia in an adolescent phenotypic male. Fertil Steril. 2005 Apr;83(4):1041 Stotland MA and Chang WT. A Better Template for Microtia Reconstruction: The Waterproof, MirrorImage Digital Photograph of the Contralateral Ear. Accepted for publication, 10-2005, in press Plast. Recons. Surg. Stotland MA, Kowalski JW, Ray BB. PatientReported Benefit and Satisfaction with Botulinum Toxin Type A Treatment of Moderate to Severe Glabellar Rhytids: Results from a Prospective Open-Label Study. Accepted for publication, 042006, in press Plast. Recon. Surg. Transplantation Surgery E. Dale Collins, MD Collins ED, Kerrigan CL. New Trends in Clinical Research. In: Plastic Surgery, Mathes SJ, Hentz (Editors). W.B. Sanders Publishing Company, New York, NY 2006 David Axelrod, MD Kaufman DB, Leventhal JR, Axelrod DA, Gallon LG, Parker MA, Stuart FP. Campath 1-H induction and prednisone-free maintenance immunotherapy in kidney transplantation. Comparison with Basiliximab induction: Long-term results. Amer J Transplantation 2005; 5:2539-48. Cunningham BL, Gear AJL, Kerrigan CL and Collins ED. Analysis of Breast Reduction Complications Derived from the BRAVO Study. Plastic and Reconstructive Surgery, 115:1597, 2005. Axelrod DA, Al-Saden P, McNatt G, Sumner S, Dixler I, Vaci M, Abecassis MM. The economic impact of MELD on liver transplant centers. Amer J Transplantation 2005; 5:2297-301 Collins ED. Invited discussion: Randy S. Roth, Ph.D., Julie C. Lowery, Ph.D., Jennifer Davis, M.H.S.A. and Edwin G. Wilkins, M.D., M.S, Quality of Life and affective distress in women seeking immediate versus delayed breast reconstruction following mastectomy for breast cancer. Plastic and Reconstructive Surgery 116 (4): 1003-1005, 2005. Axelrod DA, Leventhal JR, Gallon LG, Parker MA, Kaufman DB. Reduction of CMV Disease with Steroid-free Immunosuppresssion in SPK Transplant Recipients. Amer J Transplantation. 2005;5:1423-9. Hegel M, Moore C, Collins E, Kearing S, Gillock K, Riggs R, Clay K, Ahles T. Pre-surgical Distress, Psychiatric Syndromes and Health Related Function In Women with Newly Diagnosed Breast Cancer. Submitted to Cancer. 38 Axelrod DA, Guidinger MK, Metzger RA, Wiesner RH, Webb RL, Merion RN. Transplant Center Monitoring Using a Continuously Updatable, Risk Adjusted Technique (CUSUM). Amer J Transplantation, 6:313-323, 2006. Surgical Lab P. Jack Hoopes, DVM, PhD Chen B, Pogue BW, Zhou X, O’Hara JA, Solban N, Demidenko E, Hoopes PJ, Hasan T. Effect of Tumor Host Microenvironment on PDT in a Rat Prostate Tumor Model. Clin Cancer Res., 11 (2) 720-727, 2005. Hoopes PJ, Bergeron JA, Eskey C, Patel S, Attawia M, Pelligrino R, Ryan TP. Radiofrequency ablation of the basivertebral nerve as a potential treatment of back pain; pathologic assessment of an ovine model. Invited paper / manuscript. Proc SPIE, volume 5617, pg 156-175, 2005. Chen B, Pogue BW, Hoopes PJ, Hasan T. Combining vascular and cellular targeting regimens enhances the therapeutic effect of photodynamic therapy. Int.J.Radiation Onc Biol.Phys, 61:4 1216-1226, 2005. Savellano M, Pogue BW, Hoopes PJ, Paulsen KD. Multi-epitope targeting enhances HER2-targeted photoimmunotherapy. Cancer Res, 65: 63716379, 2005. Pogue BW, Chen B, Zhou X, Hoopes PJ. Analysis of sampling volume and tissue heterogeneity upon the in vivo detection of fluorescence. J. Biomed. Optics Focusing on Molecular Imaging and Drug Discovery, 2005. Chen B, Pogue JW, Luna JM, Hardman RL, Hoopes PJ, Hasan T. Tumor vascular permeabilization by vascular-targeting photosensitization: Effects, mechanism and therapeutic implications. Clin Cancer Research, 2005. Zhou X, Pogue BW, Chen B, Demidenko E, Hoopes PJ, Hasan T. Photosensitizer dosimetry reduce variation of photodynamic treatment response. Int. J.Radiation Onc Biol.Phys, 2005. Li H, Ballew N, Cukan M, Hoopes PJ, Youwei J, Mansfield R, Prinz B, Rios S, Sethuraman N, Stadheim TA, Strawbridge RR, Zha D, Wildt S, Gerngross T. Production of humanized IgGs in the yeast P.pastoris and use of glycoengineered yeats cell lines to elucidate glycosylation dependenet structure activity relationships. Nature Biotechnology, 2005. Urology Divi V, Proctor MC, Axelrod DA, Greenfield LJ. Thoracic outlet decompression for subclavian vein thrombosis: experience in 71 patients. Arch Surg. 2005;140:54-7. William Bihrle, MD Crane C, Bihrle W. Surgical Technique to Correct Complex Ureterointestinal Stricture With Defunctionalized Limb of Turnbull Stoma. Urology 66:416-418, 2005 Axelrod DA, Koffron A, Kulik L, Crisan E, Al-Saden P, Mulcahy M, Fryer J, Abecassis MM. Living Donor Liver Transplant for Malignancy. Transplantation. 2005; 79:363-6. E. Ann Gormley, MD Schwender CE, Ng L, McGuire E, Gormley EA. Technique and results of urethroplasty for female stricture disease. J. Urol 2006, Mar, 175, 976 -980. Dartmouth-Hitchcock Medical Center Department of Surgery 2006 Annual Report Department of Surgery Publications: 2006 John A. Heaney, MB, BCh Coecenzi TS, Tretter CP, Schwaab T, Schned AR, Heaney JA, Cole BF, Fisher JL, Ernstoff, MS. Impaired cytolytic activity in peripheral blood T cells from renal cell carcinoma patients. Clinical Immunology 227(1):6-11, 2005. Ajay K. Nangia, MBBS Ouhilal S, Turco J, Nangia A, Stotland M, and Manganiello, P: True hermaphroditism presenting as bilateral gynecomastia in an adolescent phenotypic male. Fert. & Steril. 83: 1041, 2005. Schwaab T, Nangia A. Scrotal Cancer - An Important Differential Diagnosis for the Clinician. New England Journal of Medicine 352: 2002, 2005. Parekattil S, Kuang W, Kolettis P, Pasqualotto F, Teloken P, Teloken C, Nangia A, Niederberger C, Thomas A, Agarwal A. Multi-Institutional Testing of Vasectomy Reversal Predictor. J Urol Jan 2006. Kowal B, Turco J, Nangia A. Addison’s disease presenting as Male Infertility. Fertil. Steril. 85: 1059. 2006. Kolettis P, Burns J, Nangia A, Sandlow J. Outcomes for vasovasostomy performed when only sperm parts are present in the vasal fluid. J Androl. (in press) Whitten S, Nangia A, Kolettis P. Clomiphene Citrate is successful in selected cases of hypogonadotrophic hypogonadism. Fert. & Steril. (in press) Gemery J, Nangia A, Mamourian A, Reid S. Digital 3D Modeling of the Male Pelvis and Bicycle Seats: Impact of Rider Position and Seat Design on Potential Penile Hypoxia and Erectile Dysfunction. BJU Int (in press) Nangia A. Editorial. J Urol (in press) Vascular Surgery Christopher Alessi, MD Powell RJ, Alessi CM, Nolan BW, et al. Comparison of embolization protection device-specific technical difficulties during carotid artery stenting. J Vasc Surg 2006;44:56-60. Alessi CM, et al. The Mechanics of Breathing. In: Concepts in Medical Physiology. Baltimore: Lippincott, Williams & Wilkins; 2005. Alessi CM, Zwolak R. Wound and Lymphatic Complications Following Lower Extremity Revacsularization. In: Mastery of Vascular and Endovascular Surgery. Philadelphia: Lippincott, Williams & Wilkins; 2006. Mark F Fillinger, MD Whittaker DR, Fillinger MF. The engineering of endovascular stent technology: a review. Vasc Endovascular Surg. 2006; 40(2):85-94. Sheehan MK, Ouriel K, Greenberg R, McCann R, Murphy M, Fillinger M, Wyers M, Carpenter J, Fairman R, Makaroun MS. Are type II endoleaks after endovascular aneurysm repair endograft dependent? J Vasc Surg. 2006; 43(4):657-661. www.dhmc.org/goto/surgery_annual_report Raghavan ML, Ma B, Fillinger MF. Non-Invasive Determination of Zero-Pressure Geometry of Arterial Aneurysms. Ann Biomed Eng. 2006. Powell RJ, Alessi C, Nolan B, Rzucidlo E, Fillinger M, Walsh D, Wyers M, Zwolak R, Cronenwett JL. Comparison of embolization protection devicespecific technical difficulties during carotid artery stenting. J Vasc Surg. 2006; 44(1):56-61. Marra SP, Daghlian CP, Fillinger MF, Kennedy FE. Elemental composition, morphology and mechanical properties of calcified deposits obtained from abdominal aortic aneurysms. Acta Biomater. 2006. Fillinger M. Screening for abdominal aortic aneurysm: recommendation statement. Perspect Vasc Surg Endovasc Ther. 2006; 18(1):71-73. Fillinger M. Three-dimensional analysis of enlarging aneurysms after endovascular abdominal aortic aneurysm repair in the Gore Excluder Pivotal clinical trial. J Vasc Surg. 2006; 43(5):888-895. Whittaker DR, Dwyer J, Fillinger MF. Prediction of altered endograft path during endovascular abdominal aortic aneurysm repair with the Gore Excluder. J Vasc Surg. 2005; 41(4):575-583. Raghavan ML, Fillinger MF, Marra SP, Naegelein BP, Kennedy FE. Automated methodology for determination of stress distribution in human abdominal aortic aneurysm. J Biomech Eng. 2005; 127(5):868-871. Nolan BW, Schermerhorn ML, Rowell E, Powell RJ, Fillinger MF, Rzucidlo EM, Wyers MC, Zwolak RM, Walsh DB, Cronenwett JL. Outcomes of renal artery angioplasty and stenting using low-profile systems. J Vasc Surg. 2005; 41(1):46-52. Mark C. Wyers, MD Wyers MC and Powell RJ. Invited Commentary on Cerebral micro-embolization after protected carotid artery stenting in surgical high risk patients: results of a two-year prospective study. J Vasc Surg 42: 853,2005. Whittaker DR, McCullough JP, Wyers MC, Rzucidlo EM and Powell RJ. Shifting Wallgraft position: Case reports and review of the forces affecting Wallgraft positioning. J Vasc Surg 43: 383-387, 2006. Sheehan MK, Ouriel KO, Greenberg R, McCann R, Murphy M, Fillinger M, Wyers MC, Carpenter J, Fairman R, Makaroun MS. Are Type II Endoleaks After Endovascular Aneurysm Repair Endograft Dependent? J Vasc Surg 43: 657-661, 2006 Wyers MC, Powell RJ, Nolan BW. Retrograde Mesenteric Stenting During Laparotomy for Acute Occlusive Mesenteric Ischemia. Under review, J Vasc Surg. June 2006 Robert M. Zwolak, MD, PhD Zwolak RM. Update on Government Relations and Reimbursement Issues. In: Pearce WH, Matsumura JS and Yao JST (Eds) Trends in Vascular Surgery, 2005, Greenwood Academic, Evanston, IL. Wyers M, Zwolak RM: Physiology and Diagnosis of Splanchnic Artery Occlusion. In: Rutherford RB (Ed), Vascular Surgery. Sixth edition, 2005. Rzucidlo E, Zwolak RM. Arterial Duplex. In: Rutherford RB (Ed), Vascular Surgery. Sixth edition, 2005. Alessi, C, Zwolak RM. Wound and Lymphatic Complications. In: Zelenock, Lumsden, Messina, Moneta and Huber (Eds). Mastery of Vascular and Endovascular Surgery. 2006. Nolan BW, Schermerhorn ML, Powell RJ, Rowell E, Fillinger MF, Rzucidlo EM, Wyers MC, Whittaker D, Zwolak RM, Walsh DB, Cronenwett JL. Restenosis in gold-coated renal artery stents. J Vasc Surg. 2005; 42(1):40-46. Nolan BW, Schermerhorn ML, Rowell E, Powell RJ, Fillinger MF, Rzucidlo EM, Wyers MC, Zwolak RM, Walsh DB, Cronenwett JL. Outcomes of renal artery angioplasty and stenting using low-profile systems. J Vasc Surg 2005; 41:46-52. Brown DJ, Schermerhorn ML, Powell RJ, Fillinger MF, Rzucidlo EM, Walsh DB, Wyers MC, Zwolak RM, Cronenwett JL. Mesenteric stenting for chronic mesenteric ischemia. J Vasc Surg. 2005; 42(2):268-274. Mabry CD, McCann BC, Harris HA, Martin J, Gage JO, Fischer JE, Opelka FG, Zwolak RM, Borman K, Preskitt JT, Collicott PE, McGinnis L, Cohn, I. The use of intraservice work per unit of time (IWPUT) and the Building Block Method (BBM) for the calculation of surgical work. Ann Surg 2005; 241:929-40. Mary Jo Mulligan-Kehoe, PhD Mulligan-Kehoe MJ, Schwartz GN, Zacharski LR. The functions of plasminogen activator inhibitor1: Do we have all the pieces of PAI-1? Thrombosis Res. 117(5): 483-486, 2006. Drinane MC, Sherman JA, Hall AE, Simons M, Mulligan-Kehoe MJ. Plasminogen and plasmin activity in patients with coronary artery disease. J. Thromb. Haem. 4: 1288-1295, 2006. Chittenden TW, Claes F, Lanahan AA, Autiero M, Palac RT, Tkachenko EV, Elfenbein A, Ruiz de Almodovar C, Dedkov E, Tomanek R, Li W, Westmore M, Singh J, Horowitz A, Mulligan-Kehoe MJ, Moodie KL, Zhuang ZW, Carmeliet P and Simons M. Selective regulation of arterial branching morphogenesis by synectin. Developmental Cell 10: 783-795, 2006. Sicard GA, Zwolak RM, Sidawy AN, White RA, Siami FS. Endovascular abdominal aortic aneurysm repair: Long-term outcome measures in patients at high-risk for open surgery. J Vasc Surg 2006. (in press) (online 26 April 2006) Zwolak RM: Reimbursement for Carotid Stenting: Unique Challenges for Medical Centers and Physicians. In: Chaikof E (ed), Seminars in Vascular Surgery. (in press) 39