Experimental Biology 2016 Program

Transcription

SUNDAY, APRIL 3
Across Societies
553. TEACHING, LEARNING AND TESTING IN THE
BIOLOGICAL AND BIOMEDICAL SCIENCES I
Poster
Sun. 9:00 am—San Diego Convention Center,
Exhibit Halls A-D
Education
Presentation time: 1:30 pm–3:30 pm
Recognizing that techniques and issues related to teaching
and the use of computers in research and teaching crosses all
biomedical disciplines, EB 2016 has combined education posters
from all participating societies. Please note: Posters are on display
Sunday through Tuesday. Presentation time is for Sunday only.
T2
553.1
Undergraduate Collaborative Writing in
STEM: How Learning to Write Authentically in the Discipline
Can Promote Mastery. E.M. Waters, W.M. Schlegel. Indiana
Univ. Bloomington.
T3
553.2
A PhUn Week Incursion in Australia Teaches
3-4 and 5-6 Graders Exercise Physiology. P.A. Halpin. Univ. of
New Hampshire.
T4
553.3
Combining Physiology and Health Care
Professions Education in High School-Aged Students: High
Tech PhUn! A.N. Gurovich, D. Coovert, B. Millspaugh
Storms, K. Terry. Indiana State Univ. and South Vermillion
H.S., Clinton, IN.
T5
553.4
Race Influences Student Experience in Stem
Courses. K.M.S. Johnson, N. Mantina. Beloit Col., WI.
T6
553.5
Humanizing Science and Engineering to
Reduce Health Care Delivery Inequalities. P. Cabrales, V.
Jani. UCSD.
T7
553.6
An Interdisciplinary Approach Combines
Physiology, Engineering, and Computer Science to Increase
Awareness of Stem Professions among Middle School
Students. P.A. Halpin, S. Tavares, M. Sabin. Univ. of
New Hampshire.
T8
553.7
Successful
Inquiry-Based
Activities
in
High School Physiology. S. Anjur. Illinois Math. and Sci.
Acad., Aurora.
T9
553.8
Novel Graduated Engagement Strategy Tools
for Enhancing Student Success in a Large Diverse Introductory
Physiology Course. S.J. Malmquist, W.F. Collins. Stony
Brook Univ.
T10
553.9
Fabric Muscles: A New Approach to Learning
and Understanding Human Skeletal Muscles. K.M. Mathis.
Univ. of Cincinnati Clermont Col.
T11
553.10 Pharmacokinetics in an Introductory Physics
Lab: Experimental Monitoring and Computer Modeling of
Drug Metabolism. J. Rodriguez, J. Weigal, B. Spitznagel, A.
Wilmes. St. Louis Col. of Pharm.
T12
553.11 Utilizing
Interdisciplinary
Research
Experiences and Learning Communities to Engage Students in
the Natural Sciences and Mathematics. A. Kruchten. Linfield
Col., OR.
T13
553.12 Transformation of the Introductory Biology
Experience for Biology Majors: Progress of the Northwest
Bioscience Consortium RCN-UBE. A. Kruchten, E.
Baumgartner, A. Beadles-Bohling, J. Whitman, J. Duncan, L.
Kayes, S. Kiser, W. Shriner, S. Stavrianeas. Linfield Col., OR,
Western Oregon Univ., Univ. of Portland, Whitman Col., WA,
Willamette Univ., Oregon State Univ., Lane Community Col.,
Eugene, OR and Mount Hood Community Col., Gresham, OR.
T14
553.13 Geometry in Cell Biology. D. Lin, L. West. Lee
Univ., TN.
T15
553.14 Original
Course-Based
Undergraduate
Research Experience to Detect Parasitic Worms in Local Parks
in Two Undergraduate Courses. C.A. Schmidhauser, S.A.
Blatch. Stevenson Univ.
T16
553.15 The Effect of Past Learning Experience
on Writing Performance in an Upper-Level Undergraduate
Science Course. K.E. Sylvia, K.D. Kearns, A.Z. Rangazas,
W.M. Schlegel. Indiana Univ.
T17
553.16 The Design and Impact of a New Biomedical
Seminar
Deconstruction
Course
on
Undergraduate
Learning – A Pilot Study. S. Osborne, S. Schroeter. Univ. of
British Columbia.
T18
553.17 Using Core Principles in Physiology
and Pathology to Guide Spiraled Biomedical Curriculum
Development. R.H. Selinfreund, D.W. Rodenbaugh, D.L.
Osborne. Burrell Col. of Osteo. Med., NM.
T19
553.18 Improvement in Student Data Analysis Skills
after Out-of-Class Assignments. K.L.W. Walton. Missouri
Western State Univ.
T20
553.19 Navigating from Vision to Change: Tools to
Help Biology Departments Align Curriculum with the Core
Concepts of Biology. S. Brownell, C.E. Wright, B. Couch, A.
Crowe, S. Freeman, M.P. Wenderoth. Arizona State Univ.,
Univ. of Nebraska-Lincoln and Univ. of Washington.
T21
553.20 A Conceptual Framework for the Core
Concept of Cell-Cell Communications. J. Michael, W. Cliff,
J. McFarland, A. Wright, H. Modell, P. Martinkova. Rush
Med. Col., Niagara Univ., Edmonds Community Col., Seattle,
Canisius Col., Buffalo, PERC, Seattle and Czech Acad. of
Sci., Praha.
T22
553.21 Online Simulations to Support the Teaching
of Physiology. M.dM. Quiroga, S. Clarke, R. Rajan. Monash
Univ., Australia.
T23
553.22 The Use of High Fidelity Patient Simulations to
Improve Critical Thinking Skills in First Year Medical Students.
D.M. Harris, A. Schuster, D. Kay, J.D. Kibble. Univ. of
Central Florida.
T24
553.23 Comparison of High Fidelity Patient Simulation
on the Retention of Physiology Concepts over Summer Break.
A. Jones, D. Harris. Univ. of Central Florida Col. of Med.
T25
553.24 Clinical Scenario Videos Improve D.M.D
Students’ Perception of the Basic Sciences and Ability to Apply
Content Knowledge. C.J. Metz, M.J. Metz. Univ. of Louisville.
T26
553.25 Clinical Simulations: Engaging Medical
Students in Problem-Based Learning. A. Li, H. Carvalho.
Virginia Tech Carilion Sch. of Med.
165
S
U
N
ACROSS SOCIETIES/ANATOMY
SUNDAY
T27
553.26 Physiology Meets Regenerative Medicine and
Education Becomes Research: Using Muscle Force Production
to Assess Ischemia and Arteriogenesis in a Masters-Level
Cell Transplantation Laboratory. T.R. Cardinal. Cal Poly, San
Luis Obispo.
T28
553.27 Pathophysiology in Postgenomic ERA –
Natural Etiopathogenetic Algorhythms and Clusters of Health
Disorders. Z. Kovac. Med. Sch., Univ. of Zabreb, Croatia.
T29
553.28 Quantitative and Qualitative Analysis of Medical
Students’ Research Output in Six Developing Countries. A.S.
Obad, H.T. Albarqawi, A.M. Eshaq, H.N. Hoilat, A.A. AlKhateeb, A.M. Fothan, A.H. AlSaffar, W.M. Al-Najjar, A.M.
Bakather, M.A. Shareef, T.A. Khan, A.A. AlAmodi. Alfaisal
Univ., Saudi Arabia, St. Vincent Mercy Med. Ctr.-OH, Toledo
and Univ. of Mississippi Med. Ctr.
T30
553.29 Statistics
Education
for
Physiologists:
Are Students Learning the Skills That They Need? T.L.
Weissgerber, V.D. Garovic, J. Milin-Lazovic, S.J. Winham, Z.
Obradovic, J.P. Trzeciakowski, N.M. Milic. Mayo Clin., Univ.
of Belgrade, Temple Univ. and Texas A&M, Temple.
T31
553.30 Student Learning Gains through Curriculum
Modification in a College Introductory Human Nutrition Course.
M.L. Stewart. Univ. of Hawaii at Manoa.
T32
553.31 The Starling Actuator – the Implementation of
Starling’s Law of the Heart within a Mechanical Model of the
Cardiovascular System. G.L. Strauss, T.E. Sweeney. Univ.
of Scranton.
T33
553.32 Modeling Aortic Insufficiency in the Scranton
Cardiovascular Model. M.T. Graham, T.E. Sweeney. Univ.
of Scranton.
T34
553.33 A Mathematical Model of the Cardiovascular
System Based on the Scranton Cardiovascular Model. N.E.
Frederick, J.R.N. Jimenez, J.M. Graham, T.E. Sweeney. Univ.
of Scranton.
T35
553.34 Animating the Kidney: Temporal and Spatial
Integration of Complex Renal Mechanisms. G.D. Guttmann,
D.R. Guttmann, R.T. Mallet. Univ. of North Texas Hlth. Sci. Ctr.
and Univ. of Windsor, Canada.
T36
553.35 Exploring Oxygen Transport by Hemoglobin: A
Computer Simulation for Students. K. Christmas, M. Chirillo,
D.U. Silverthorn. Univ. of Texas at Austin, Univ. of Texas Hlth.
Sci. Ctr. at Houston and Dell Med. Sch. Univ. of Texas at Austin.
T37
553.36 Can Visual Memory Devices Aid Retention and
Short-Term Recall of Pre-clinical Science Knowledge? A.L.
Hawkins, J.D. Kibble. Univ. of Central Florida.
Anatomy
554. CARDIOVASCULAR BIOLOGY: DEVELOPMENT
AND GROWTH
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
Cardiovascular Biology
Presentation time: O
dd Board# 12:00 pm–1:00 pm
Even Board# 1:00 pm–2:00 pm
A259 554.1
Lipidic Agent as Vascular Constrast-Medium for
MRI (3T) in Foetal and Embryonic Development: FeasabilityStudy on Ex Vivo Rabbit Foetus at 3T. R. Tonnelet, M. Perez,
P.A. Gondim Teixeira, A. Sewonu, M. Beaumont, G. Hossu,
M. Labrousse, M. Braun. Univ. de Lorraine UL and CHU,
Nancy and Univ. Reims Champagne, France.
A260 554.2
Hydrostatic
Stress
Regulates
Tissue
Compaction, Polarity, and Matrix Stiffness in the Developing
Atrioventricular Valve. D.M. Bassen, R. Singh, R.A. Gould,
P.R. Buskohl, J.T. Butcher. Cornell Univ.
A261 554.3
Light-Sheet
Microscopy
to
Elucidate
Hemodynamic Forces and Modulation of Cardiac Trabeculation:
Implications for Embryonic Contractile Function. J. Lee, R.R.S.
Packard, H. Xu, H. Kang, K.I. Baek, N. Jen, C.C.J. Kuo, N.C.
Chi, C-m. Ho, R. Li, T. Hsiai. UCLA, USC and UCSD.
A262 554.4
Double Superior Vena Cava: A Case Report.
O. Rosenthal, S. Lobo, H. Sandhaus, H. Kopelman, S.
Zarkar, R. Menezes. TouroCOM, Middletown, NY and Univ. of
Dammam, Saudi Arabia.
A263 554.5
CXCL12 and Vascular Maturation of the
Coronary System during Heart Development. S. Cavallero,
H. Shen, C. Yi, R.K. Subramanyan, H. Sucov. Univ. of So.
California Keck Sch. of Med. (230.3)
166
555. CARDIOVASCULAR BIOLOGY: DYSFUNCTION;
DISEASE; GENETIC DISORDERS
A264 555.1
An Explanatory Computational Simulation of
Contiguous Capillary Occlusion in Diabetic Retinopathy Based
on Patient-Derived Vasculature. X. Fu, J.S. Gens, J.A. Glazier,
S. Burns, T.J. Gast. Indiana Univ.
A265 555.2
Genotype Discrimination Using Facial and
Body Anthropometry among Hausas. M.G. Taura, L.H. Adamu,
A. Gudaji. Bayero Univ. Kano, Nigeria.
A266 555.3
Loss of Axin2 Leads to Myxomatous Valve
Disease. A. Hulin, K. Yutzey. Cincinnati Children’s Hosp.
Med. Ctr.
A267 555.4
Trichloroethylene Produced Defects in the
Developing Heart Involve the Transcription Factor, HNF4a. S.
Chen, M. Nunez, K. Ismail, O. Selmin, R.B. Runyan. Univ.
of Arizona.
A268 555.5
Trapped Lung Secondary to Cardiomegaly in a
78 Year-Old Male with Congestive Heart Failure. A.H. Amabile,
R.M. DePhilip, S.D. Moffatt-Bruce. The Ohio State Univ.
SUNDAYANATOMY
556. ANATOMY: CARDIOVASCULAR
Poster
558. CARDIOVASCULAR BIOLOGY:
BIOENGINEERING, REPAIR
AND REGENERATION
Exhibit Halls A-D
Poster
Exhibit Halls A-D
A269 556.1
Morphometric Parameters to Evaluate
Zebrafish Heart: A Model to Study Cardiovascular Function.
R.A. Vargas, I.C. Vásquez. Pontificia Univ. Javeriana, Bogotá.
A270 556.2
Surgical Radiologic Anatomy of Aberrant Right
Subclavian Artery (Arteria Lusoria): A Study on 160 CT Scans.
N. Settembre, S. Malikov, F. Jeannon, Z. Bouziane. Nancy
Univ. Hosp., France.
A271 556.3
Pre-operative Eligibility for Minimally Invasive
Coronary Artery Bypass Grafting Using the Davinci Robot:
An Examination of Anatomical Parameters Using Computed
Tomography. K. Dillon, M. Johnson, I. Chan, B. Kiaii. Western
Univ. and London Hlth. Sci. Ctr., Canada.
A272 556.4
Bilateral Intra-individual Comparison of
Vascular Structure following Eight Weeks of Unilateral Maximal
Interval Handgrip Training in Post-menopausal Women. D.C.
Bentley, S.G. Thomas. Univ. of Toronto.
557. CARDIOVASCULAR BIOLOGY: ANATOMY
AND MORPHOLOGY
Poster
Exhibit Halls A-D
A273 557.1
Retrospective
Computed
Tomography
Angiogram Investigation on the Subclavian Artery Branching
Pattern and Origin. J. Ryu, O. Scallan, M. Johnson, T. Wilson,
A. Power. Schulich Sch. of Med. & Dent., Western Univ. and
Victoria Hosp., London Hlth. Sci. Ctr., Canada.
A274 557.2
Morphological Analyses of the Arterial Supply
to the Brain. E.G.M. Kyle, V. Hachinski, D.A. Ramsay, K.A.
Rogers. Western Univ., Canada.
A275 557.3
A Tale of Two Arches. B.M. Wilson, J.M.
Williams. Rush Univ. Med. Ctr.
A276 557.4
Variation of the Common Carotid Artery
Diameter Related to Age. M. Tracy-Bee, S.T. Barton, J. Zurke,
N. Hamka. Univ. of Detroit Mercy and UCSD.
A277 557.5
A Unique Case of Branching Pattern in the
Superior Mediastinum: A Brachiocephalic Trunk with Four
Branches, and the Left Thyrocervical Trunk Arising from the
Aortic Arch. N. Valentin Carro, W. Veras Tavares. Univ. Central
del Caribe, PR.
A278 557.6
Perforator Angiosomes of the Anterior Knee
Region. L. Hirtler, A. Lübbers. Med. Univ. of Vienna, Austria.
A279 558.1
Characterization of the Unique Viscoelastic
Properties of the Mitral Valve Anterior Leaflet. L. Figueroa,
B. Brazile, S. Lin, B. Nelson, J. Liao. Univ. of Puerto Rico,
Ponce, Mississippi State Univ. and Univ. of Pittsburgh.
A280 367.3
Functional Characterization of Isl2/coupTFIb
Activation Targets in Vascular Development. Y-S. Wang. Natl.
Sun Yat-sen Univ., Taiwan.
560. ANATOMY: NEURAL
Poster
Exhibit Halls A-D
Neurobiology
A281 560.1
The Serratus Anterior Plane Block: An
Anatomical Investigation of the Regional Spread of Anesthetic
Using Ultrasound-Guided Injection. L. Varghese, M. Johnson,
M. Barbeau, S. Vijayashankar Rakesh, P. Magsaysay, S.
Ganapathy. Western Univ. and London Hlth. Sci. Ctr., Canada.
A282 560.2
The
Interplay
between
Taste
and
Chemesthesis. A.Y. Huang, S.Y. Wu. So. Illinois Univ. Sch.
of Med.
A283 560.3
Middle and Inner Ear 3d Reconstructions Using
High Resolution X-Ray Micro-tomography. M. Labrousse, X.
Dubernard, N. Settembre, R. Tonnelet, C. Avisse, J. Devy, Y.
Renard. Univ. de Reims Champagne-Ardenne, CHU Reims,
CHU Nancy and Univ. de Lorraine, France.
561. NEUROBIOLOGY: BEHAVIOR;
NEUROPSYCHIATRIC DISORDERS;
DISEASE; AGING
Poster
Exhibit Halls A-D
Neurobiology
A284 561.1
Cystatin Peptide Prevents Alzheimer’s
Pathology in CRND8 AD Mice. P.A. Shaw. Icahn Sch. of Med.
at Mount Sinai.
167
S
U
N
ANATOMYSUNDAY
A285 561.2
Drug Combinations Modulate Stem Cell
Proliferation in the Subventricular Zone of 11-Month-Old
Rats: Innate Gender Differences Could Explain Alzheimer’s
Susceptibility. T. Sulehria, N. Sharma, S. Gagle, A.M. Corbett.
Wright State Univ.
A286 561.3
Examining the Immunomodulatory Effects of
IL-12 in a Mouse Model of Alzheimer’s Disease. L. Klaidman,
D.D. Ellefson, T. Gallaher, E. Stark, S.P. Schettler. UCLA and
Sarcix Inc., Riverside.
A287 561.4
Vitamin K2 Prevents Beta Amyloid Peptide and
Vitamin K3-Induced Cell Death. T. McGarvey, P. Ramaraj, S.S.
Hassan. A. T. Still Univ.
A288 561.5
Protracted Withdrawal from Cocaine: A Role for
mGlu2/3 Receptors in the vmPFC? C.B. Shin, M.A. RuppertMajer, M.M. Serchia, T.E. Kippin, K.K. Szumlinski. Univ. of
California Santa Barbara.
A289 561.6
Estradiol Increases Choice of Cocaine over
Food in Male Rats. J.R. Bagley, R. Bozadjian, L. Bubalo,
J. Adams, S. Ghobadi, T.E. Kippin. Univ. of California,
Santa Barbara.
A290 561.7
Extended-Access and Yoked-Access to
Cocaine Self-Administration Have Distinct Behavioral and
Molecular Profiles. K.L. Ploense, P. Vieira, T.E. Kippin. Univ.
of Californa Santa Barbara.
A291 561.8
Thymoquinone Enhances Neurogenesis to
a Greater Extent in Middle-Aged Than in Young Aged Rat in
Chronic Epilepsy. S.A. Brito, M.S. Rao. Kuwait Univ.
A292 561.9
Behavioral Resiliency of Mice to Repeated
Mild Cerebral Concussion: Are There Interactions with Dietary
Polyunsaturated Fatty Acids? R.W. Clough, N. Viscomi, G.
Rose, E. Hayashi, W. Banz, J. Cheatwood. So. Illinois Univ
Sch. of Med.
A293 561.10 Soy Protein Diet Preserves Skilled Ladder Rung
Walking Performance after Stroke Better Than Isoflavones
Alone in Adult and Aged Male Rats. J.L. Cheatwood, D.G.
Wallace, D.N. Butteiger, W.J. Banz. So. Illinois Univ., No.
Illinois Univ. and DuPont Nutr. & Hlth., St. Louis.
A294 561.11 Loss of Nf1 Function Causes Stereotypic
Grooming Behavior in Drosophila melanogaster Y. Velázquez,
S.M. Tomchik. Univ. of Puerto Rico in Ponce and The Scripps
Res. Inst., Jupiter, FL.
A295 561.12 Behavioral Evidence of Transient versus
Persistent Tinnitus Induced by Loud Noise Exposure in a
Novel Rat Model. K. Beh, M. Typlt, G. Sigel, A. Schormans,
D. Stolzberg, B.L. Allman. Univ. of Western Ontario. (371.5)
562. NEUROBIOLOGY: BRAIN
Poster
Exhibit Halls A-D
Neurobiology
A296 562.1
Morphometry of Brain Longitudinal Fissure
and Its Possible Clinical Correlations. E.P. Camara, A.J.A.X.
Pinto, M.R. Tavares, V.P.S. Fazan, B.C. Netto, H.R. de Paula,
N.F. Oliveira. Univ. José do Rosário Vellano, Brazil and Univ.
of São Paulo.
168
A297 562.2
Morphometry of the Corpus Callosum and Its
Possible Clinical Correlations. E.P. Camara, A.J.A.X. Pinto,
M.R. Tavares, V.P.S. Fazan, M. Amorim, N.F. Oliveira, H.R. de
Paula. Univ. José do Rosário Vellano, Brazil and Univ. of São
Paulo, Ribeirão Preto.
A298 562.3
Level of Tool-Use Proficiency in Chimpanzees
Is Associated with Differences in Gray Matter Distribution in
the Inferior Parietal Cortex: A Voxel-Based Morphometry
Study. L.D. Reyes, W.D. Hopkins, C.C. Sherwood. George
Washington Univ., Georgia State Univ. and Yerkes Natl.
Primate Res. Ctr., Atlanta.
A299 562.4
Cognitive Function as Related to Cumulative
Head Impact Exposure in Football: Effects of Position. D. Brewer
Deluce, T.D. Wilson, A.M. Owen. Western Univ., Canada.
A300 562.5
Morphometric Analysis of the Blood-Brain
Barrier in the Peri-infarct Zone in Young Adult and Aged
Mice. P.C. Nahirney, P. Reeson, C.E. Brown. Univ. of
Victoria, Canada.
A301 562.6
Cells Lining the Lateral Ventricle Show
Dynamic Protein Expression following Tail Loss in the Leopard
Gecko. R.P. McDonald, E.A.B. Gilbert, A. Macdonald, M.K.
Vickaryous. Univ. of Guelph, Canada.
563. NEUROBIOLOGY: DEVELOPMENT
Poster
Exhibit Halls A-D
Neurobiology
A302 563.1
Characterization of a NOGO-A Associated
Enhancer Element in Chicken. C.U. Pira, S.A. Caltharp, S.
Magaki, E. Haro, A. Fukuda, K.C. Oberg. Loma Linda Univ.,
Children’s Healthcare of Atlanta and UCLA Med. Ctr.
A303 563.2
Regulation of the Development of Human
Neurons by Substratum Elasticity. L.M. Rivera-Pérez, R.
Nichol, T. Gomez. Univ. of Puerto Rico - Ponce and Univ.
of Wisconsin-Madison.
564. NEUROBIOLOGY: NEURONAL AND
SPINAL CORD DEGENERATION, REPAIR
AND REGENERATION
Poster
Exhibit Halls A-D
Neurobiology
A304 564.1
Quantification of Substance P in Dorsal Root
Ganglion Neurons, after Nociceptive Stimulation during the
Neonatal Period. A.L.B. Simões, C.S. Carvalho, E.C. Carmo,
N.B. Machado, L.S. Sanada, V.P.S. Fazan. Sch. of Med. of
Ribeirão Preto, Brazil.
SUNDAYANATOMY
A305 564.2
An
Immunohistochemistry
Protocol
to
Identify Satellite Glial Cells Positive for GFAP in the Dorsal
Root Ganglion of Rats in Different Ages. A.L.B. Simões, C.
Giorgetto, E.C. Carmo, N.B. Machado, L.S. Sanada, V.P.S.
Fazan. Sch. of Med. of Ribeirão Preto, Brazil.
A306 564.3
Neuritin, a New Potential Target for Optic
Nerve Injury Therapy. J. Xu, W. Cao, W. Liu, H. Ma, A. Qi, T.
Huang, L. Li, F. Liu. Second Military Med. Univ., Shanghai.
A307 564.4
Histological and Functional Study of Laser and
Latex Treatments on Crushed Sciatic Nerve. F.J. Dias, I-s.
Watanabe, M.M. Iyomasa, J. Coutinho-Netto, J.P.M. Issa,
R. Fuentes, E. Borie, V.P.S. Fazan. Ribeirão Preto Med. Sch.,
Univ. of São Paulo, Dent. Sch., Univ. de La Frontera, Chile and
Inst. of Biomed. Sci., Univ. of São Paulo.
A308 564.5
The Regenerative Potential of the Axolotl
Spinal Cord: A Blunt Spinal Cord Injury Model. M.M. Thygesen,
H. Lauridsen, M. Pedersen, M.M. Rasmussen. Aarhus Univ.
and Aarhus Univ. Hosp., Denmark.
A309 564.6
Ependymal Cells Are a Heterogeneous
Population in the Spinal Cord of the Leopard Gecko. E.A.B.
Gilbert, M.K. Vickaryous. Univ. of Guelph, Canada.
565. ANATOMY EDUCATION: MEDICAL STUDENTS
AS TEACHERS/PEER TEACHING
Poster
Exhibit Halls A-D
Education and Teaching
A310 565.1
Outcomes of Using Peer-Mentors and Bidirectional Development of CanMEDS Core Competencies
at a Distributed Medical Education Site. M.T. Pignanelli, J.
Williams, C. Hillman, S. Mekhaiel, A. Farias. Schulich Sch. of
Med. & Dent., Windsor, Canada.
A311 565.2
Gaining Competencies during Early Medical
Training: Medical Students as Teaching Assistants in
Dissection-Based Anatomy Course. M.T. Brown, G. Zhang.
Thomas Jefferson Univ.
A312 565.3
A Longitudinal Study of the Utility and Efficacy
of a Peer-Based Anatomy Tutoring Program for First-Year
Medical Students: 2011-2015 N.A. Schmalz, C. Escovedo, D.
Harrison, J. Lentz, L. Stahl, S. Thakur, N. Parker, E. Stark.
Indiana Univ. Sch. of Med., Mattel Children’s Hosp. UCLA,
Children’s Hosp. Los Angeles, Ronald Reagan UCLA Med. Ctr.,
Ofc. of Admisssions and David Geffen Sch. of Med. at UCLA.
A313 565.4
Steering Illusions of Competence: A NearPeer Driven Integrated Approach to Improving Performance
of At-Risk Students in a Gross Anatomy Course. P. Salem, L.
Schmelkin, N. Lachman, W. Pawlina. Mayo Med. Sch.
A314 565.5
Role of Peer-Teaching in Graduate Anatomical
Sciences Education. L.M.J. Lee. Univ. of Coloradao Sch. of
Med., Aurora.
566. ANATOMY EDUCATION:
STUDENT SELF/PEER-ASSESSMENT
Poster
Exhibit Halls A-D
A315 566.1
A Newly Modified Research Design for the
Assessment of an In-Class, Student Driven Teaching Activity.
D.C. Bentley, C.L. DeZorzi, N. Richardson. Univ. of Toronto,
George Brown Col. and York Univ., Toronto.
A316 566.2
Rubric Design for Evaluating Reciprocal Peer
Teaching in Gross Anatomy Impacts Student Performance
and Satisfaction. B.F. Giffin, A. Marshall, L. Lukin. Univ. of
Cincinnati Col. of Med.
A317 566.3
Learning to Lead: Facilitating Leadership Skills
through Peer and Faculty Feedback in a Team-Based Anatomy
Course. S.R. Halasz, M.H. Ansari, W. Pawlina, N. Lachman.
Mayo Med. Sch. and Mayo Clin.
567. ANATOMY EDUCATION: ASSESSMENT
Poster
Exhibit Halls A-D
A318 567.1
Assessing Assessments: The Effect of Virtual
Assessment on Measuring Student Success. G.M. Fox, K.
Alsup. Univ. of Michigan Med. Sch.
A319 567.2
Accuracy of Localisation and Cause of
Preclinically Suspected Diagnose: Explorative Analysis of
Retrospective Data of 700 Patients. L. Hirtler, F. Huber. Med.
Univ. of Vienna.
A320 567.3
Evaluation of a Hands-on Anatomy-Centered
Ultrasound Curriculum in a Graduate Gross Anatomy Course.
D. Royer, R. Kessler, J. Stowell. Univ. of Colorado Anschutz
Med. Campus, Univ. of Michigan Hlth. Syst. and Maricopa
Med. Ctr., Phoenix.
A321 567.4
Evaluation of the Inclusion of Weekly Quizzes
on Academic Performance in First Year Medical Students. J.
Collier, C.A. Nichols, A.C. Edmondson. Med. Col. of Georgia
at Augusta Univ.
A322 567.5
A Look at Questions Asked in Gross Anatomy
Lab: An Analysis at Indiana University School of Medicine Bloomington. M. Taylor. Indiana Univ.
A323 567.6
Use of iPad and ExamSoft™ in Administering
Morphological Sciences Practical Examination in an Integrated
Curriculum. C. Vasan, E. Goldman, M. Gentile, S. Perlis, J.
Ferrarie, C. Ferretti, P. Greenfield, N. Vasan. Cooper Med.
Sch. of Rowan Univ.
A324 567.7
A Cadaveric Procedural Anatomy Course
Enhances Operative Competence. G. Sharma, M.A. Aycart, T.
van Houten, D.S. Smink, R. Askari, J.D. Gates. Brigham and
Women’s Hosp., Harvard Med. Sch.
169
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A325 567.8
Gross Anatomy Dissection Improves Exam
Scores Amongst Medical and Allied Health Students. R.J.
Anders, A.C. Edmondson, C.M. Martin, K. Wheeler. Med.
Col. of Georgia - Augusta Univ. and Western Univ., Canada.
TECHNOLOGY ASSISTED
Poster
Exhibit Halls A-D
A326 568.1
How
Do
Alternative
and
Traditional
Dissemination Metrics Compare in Medical Education
Scholarship? C.J. Ramnanan, K. Ambacher, A. Amath, C.
O’Brien, T.J. Wood, J.J. Leddy. Univ. of Ottawa.
A327 568.2
The Anatomy of E-Learning Tools: Are Modern
E-Learning Tools a Suitable Replacement for Traditional
Learning Methods? S.E. Van Nuland, K.A. Rogers. Western
Univ., Canada.
A328 568.3
Tailoring Virtual Content to Curricula: BlueLink.
K. Alsup, G.M. Fox. Univ. of Michigan.
A329 568.4
Effectiveness of BlueLink Cadaveric Multimedia
Resources in a Pre-professional Course. S.N. Dudgeon, B.K.
Alsup, G.M. Fox. Univ. of Michigan Med. Sch.
A330 568.5
Use of an Anatomy eBook to Document and
Discuss Anatomical Variation. B.J. Thompson, M. Barremkala,
A. Raoof, S.M. Attardi, A.M. Blenc, I. Hajj Hussein, W. Forbes,
D.J. Gould, J.M. Venuti. Oakland Univ. William Beaumont Sch.
of Med. and Beaumont Hosp., Royal Oak, MI.
A331 568.6
The Use of Facebook to Support Anatomy
Learning. M. El-Sherbiny, M.A. Eladl, M.E. Abdalla.
ALMaarefa Col., Saudi Arabia, Univ. of Mansoura, Egypt and
Univ. of Sharjah, United Arab Emirates.
A332 568.7
Development and Use of a Web-Based Human
Dissection Video Library at MCW. P. Biggs, D. Pierce, T.
Hoagland. Med. Col. of Wisconsin.
A333 568.8
Implementing the Sony Action Cam® and
Camtasia® Software to Supplement Dissection-Based
Anatomy in DPT Programs. J. Immonen, C. Siefring, K.
Chung-Hoon, J.W. McWhorter. Rocky Mountain Univ. of Hlth.
Professions, Provo.
A334 568.9
Decreasing Bias of the Traditional Structure
Tagging Method during an Anatomy Practical Lab Exam Using
Google Glass. B. Benninger, I. Blandford. Western Univ. of
Hlth. Sci., Lebanon, OR.
A335 568.10 Integrated Sequential Layering – an Effective
Method for Teaching and Learning Anatomy in the Digital Age.
L. Dissabandara, S.N. Nirathanan. Griffith Univ., Australia.
A336 568.11 Teaching Ultrasound of the Musculoskeletal
System during Anatomy Using the 7D Interactive Software
Program. I. Blandford, B. Benninger. Western Univ. of Hlth.
Sci., OR.
A337 568.12 From the Novice to the Experienced Ultrasound
User: 7D Interactive Software Is Your Personal Tutor. I.
Blandford, B. Benninger. Western Univ. of Hlth. Sci., OR.
A338 568.13 Self- and Peer Assessment of Professional
Speaking Skills Using a Classroom Response System: Three
“Clicker” Systems and Ten Years of Data Collection. L.K.
Sprunger. Washington State Univ.
170
A339 568.14 Development and Implementation of a Novel
Integrated Anatomical Sciences Mobile App for Medical
Students. D. Harmon, E. Kalmar, J. Burgoon. UCSF and The
Ohio State Univ.
A340 568.15 A Virtual Laboratory and Game-Based App
to Facilitate Self-Directed Online Learning in Histology. N.
Swailes. Univ. of Iowa.
A341 568.16 The Changing Face of Histology: An Old Idea
for a New Era. P.A. Shaw. Icahn Sch. of Med. at Mount Sinai.
A342 568.17 Digital Microscopy: A New Method for Histology
Teaching. B. Romana-Souza, M.A. Santos-Silva, L.C. Porto,
A. Monte-Alto-Costa. State Univ. of Rio de Janeiro, Brazil.
A343 568.18 HistoConnect: An Online Integrated Module.
J-P. Iskandar, K. Doyle, A.M. Blenc, A. Jurjus, I. Hajj Hussein.
Oakland Univ. William Beaumont Sch. of Med. and American
Univ. of Beirut.
A344 568.19 Development of a 3D Interactive Model for
Teaching Intercortical Connectivity of Cerebral White Matter
Tracts. J. Bergden, M.E. Stabio. Univ. of Colorado Anschutz
Med. Campus.
A345 568.20 Utility of Virtual 3D Animations and 3D Printed
Models of Heart Development in Graduate Embryology
Education. A. Richardson, L.M.J. Lee. Univ. of Colorado Sch.
of Med.
A346 568.21 Interactive 3D Atlas of the Human Hand:
Anatomical Specimens, Illustrations and CT Scans. L.
Burchianti, M.D. Barros, D.F. Curcio. Santa Casa Sch. of
Med. Sci., São Paulo and Icahn Sch. of Med. at Mount Sinai.
A347 568.22 Development of 3D Stereoscopic Virtual
Model of the Pelvis from Computed Tomography Images. A.M.
James, A.D. Smith, D. Cui. Univ. of Mississippi Med. Ctr.
A348 568.23 X-perience – an Interactive Viewing Platform
Displaying Radiographic Profiles of Cadavers for Educational
Purposes. E. Nic an Riogh, G.F. Perry, J.F..X. Jones,
A. Tattersall, M. Heduan, R.H. Stern, P. MacMahon, N.
Giannotti, M. Davis. University Col. Dublin Sch. of Med.,
Mount Sinai Hosp., NY and Mater Misericordiae Univ. Hosp.,
Dublin. (225.3)
569. ANATOMY EDUCATION: FACTORS AFFECTING
STUDENT PERFORMANCE
Poster
Exhibit Halls A-D
A349 569.1
Making Meaning: A Qualitative Inquiry
into Undergraduate Meta-emotional and Socio-cognitive
Development during Cadaver Dissection. P.A.G. Soneral, S.A.
Wyse, T. Shaw. Bethel Univ.
A350 569.2
The Effect of Focused Active Learning
Strategies on Student Engagement with Respect to
Socioeconomic Class. T. Birk, V. Lee. Ivy Tech Community
Col., Lafayette, IN and So. Adventist Univ., Collegedale, TN.
A351 569.3
Performance in an Anatomy Pre-course
Predicts Performance in a Professional Veterinary Anatomy
Curriculum. M.A. McNulty, C. Stevens-Sparks, J. Taboada, A.
Daniel, M.D. Lazarus. LSU Sch. of Vet. Med. and Monash Univ.
SUNDAYANATOMY
A352 569.4
Correlation between Pre-medical Exposure to
Anatomy and Performance in Medical Gross Anatomy. E.M.
Robertson, A.J. Notebaert, A.R. Sinning, R.D. Darling. Univ.
of Mississippi Med. Ctr.
A353 569.5
Examination of the Roles of Learning Style and
Learning Strategy on the Academic Performance of First Year
Medical Students. C.T. Nichols, A.C. Edmondson. Med. Col.
of Georgia at Augusta Univ.
A354 569.6
VARK Learning Styles of First Year Dental
Students. S. Alshehry, J. Sedlmayr, J. Cork. LSU Hlth. Sci.
Ctr., New Orleans.
A355 569.7
Assessing Musculoskeletal Competency in
Osteopathic Medical Students. S.A. McCarthy, L. Olson,
C.C.A. Chen, R. Kulesza, J.K. Kalmey. Univ. of Vermont and
Lake Erie Col. of Osteo. Med., PA.
A356 569.8
Optional Online Quizzes Increase Student
Success on Exams in an Undergraduate Human Anatomy
Course. N. Richardson. York Univ., Canada.
A357 569.9
Customizing Anatomy Videos to Curricula
Maximizes Learning and Retention: Implications for First Year
Medical Education. D. Mastriano, J. Kurtzman, S. PaskinFlerlage, D. Brady, P. Eucalitto, B. Laurance, S. Márquez.
SUNY Downstate Med. Ctr.
A358 569.10 Does Lecture Attendance Matter? A Study
of Exam Performance in Medical Neurobiology. E.R. Meyer,
A.J. Notebaert, E. Perkins, J.C. Lynch, K.L. Simpson, R.D.
Darling. Univ. of Mississippi Med. Ctr.
A359 569.11 The Impact of Team-Based Learning on
Physician Assistant Student’s Academic Performance in
Gross Anatomy. V. Makeeva, J.A. Isbell, K. Caruthers, W.
Brooks. Univ. of Alabama Sch. of Med. and Univ. of Alabama
at Birmingham.
A360 569.12 Performance Statistics of Structures: Does the
Anatomical Region or Structure Type Impact Item Difficulty
or Discrimination on Gross Anatomy Practical Examinations?
A.R. Thompson, C.E. Cotter, J.B. Hanna. Univ. of Cincinnati
Col. of Med. and West Virginia Sch. of Osteo. Med.
A361 569.13 Problem Sets Allow for Multiple Competency
Acquisition in First Year Neuroscience Course. M.D. Lameka,
W.G. Pearson, A.C. Edmondson. Med. Col. of Georgia at
Augusta Univ.
570. ANATOMY EDUCATION: SPATIAL ABILITIES
Poster
Exhibit Halls A-D
A362 570.1
Spatial Abilities and Pictures of Objects
Recognized from Haptic Perception: Effect of Short-Term
Memory. J. Langlois, Y. Dagenais, M. Martin, R. Lemieux,
M. Lecourtois, E. Yetisir, C. Bellemare, G. Bergeron, S.J.
Hamstra, G.A. Wells. Sherbrooke Univ. Hosp., Univ. of
Sherbrooke, Univ. of Ottawa Heart Inst.
A363 570.2
Spatial Abilities, Anatomy Knowledge and
Technical Skills: A Systematic Review. J. Langlois, C.
Bellemare, J. Toulouse, G.A. Wells. Hosp. Ctr., Univ. of
Sherbrooke, Univ. of Ottawa and Univ. of Ottawa Heart Inst.
A364 570.3
Spatial Organization and Learning. L. Alazzeh.
San Francisco State Univ.
A365 570.4
The Influence of Spatial Ability on Anatomy
Examination Questions in an Integrated Medical Curriculum. J.
Xiong, A.C. Edmondson, C. Martin. Med. Col. of Georgia at
Augusta Univ., Augusta Univ. and Univ. of Western Ontario.
A366 570.5
The Influence of Spatial Ability on Medical
Student Performance in the Basic Sciences. A. Willis, A.
Edmondson, C. Martin. Med. Col. of Georgia at Augusta
Univ., Augusta Univ. and Univ. of Western Ontario.
A367 570.6
Effect of Spatial Ability on Enhancing
Neuroanatomy Education with an Interactive 3D E-Learning
Module. L. Allen, R. Eagleson, S. deRibaupierre. Western
Univ., Canada.
A368 570.7
Stereoscopic (3D) Visualization Improves
Medical Student Comprehension of Head and Neck Vascular
Anatomy. D. Cui, T.D. Wilson, R.W. Rockhold, M.N. Lehman,
J.C. Lynch. Univ. of Mississippi Med. Ctr. and Western
Univ., Canada.
A369 570.8
Potential of “Living” Photography in an
Online Anatomy Resource to Improve Students’ 3D Spatial
Understanding. M. Pascoe, L. Lee. Univ of Colorado, Aurora.
A370 570.9
Guiding Low Spatial Ability Individuals through
Visual Salience Cueing: The Dual Importance of Where and
When to Look. V. Roach, G. Fraser, J. Kryklywy, D. Mitchell,
T.D. Wilson. Western Univ., Canada.
A371 570.10 Teaching Students to See: Visual Learning
Instruction for Two Different Undergraduate Anatomy Courses.
B. Barger. Indiana Univ.
171
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Biochemistry and Molecular Biology
571. CRISPR MECHANISM AND FUNCTION
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C1
571.1
Live Cell Interrogation of dCas9:sgRNA
Dynamics Off and at the Target. T. Pederson. Univ. of
Massachusetts Med. Sch.
C2
571.2
Generation of a Foxc2 Gene Knockout Murine
Melanoma Cell Line via CRISPR Cas9 Genome Editing
Technology. J. Thompson, K. Hargadon. Hampden-Sydney
Col., VA.
C3
571.3
Control of CRISPR Priming and Interference
Activities by a Cascade-Activated Switch. N.R. Whitis, C. Xue,
D.G. Sashital. Iowa State Univ.
C4
571.4
Utilizing the CRISPR-Cas System to Excise
and Study the Insulin Enhancer. S. Yang, R. Rose. North
Carolina State Univ.
C5
571.5
Optimization of DNA, RNA and RNP Delivery
Methods for Efficient CRISPR/Cas9 Mediated Mammalian Cell
Engineering. C. Khodthong, J. Snow, L. Juckem. Miirus Bio
LLC, Madison, WI.
C6
571.6
A Small Molecule Enhanced CRISPR/Cas9
Methodology for Genome Editing of Dog (Canis familiaris)
Induced Pluripotent Stem Cells. F. Federico, N. Federico, G.
Sternik, T. Federico, B. Esmaeli-Azad. Cathedral Catholic
H.S., San Diego, San Diego State Univ., DNAmicroarray Inc.,
San Diego and Carlsbad and UCLA.
C7
571.7
Optimization of CRISPR/Cas9 PlatformMediated Gene Editing of Swine Embryos for the Creation
of Novel Biomedical Swine Models. D.T. Schomberg,
J.J. Meudt, K.J. Krentz, C.D. Rubinstein, A. Zhang, D.
Shanmuganayagam. Univ. of Wisconsin-Madison.
572.DNA
Poster
Exhibit Halls A-D
C8
572.1
Synthesis and Characterization of Nucleic Acid
Aptamers Targeted at Aspergillus Surface Carbohydrates. J.A.
Bush, C.E. Rohlman. Albion Col., MI.
C9
572.2
Design and Construct a Type of Fluorescently
Labeled Circular DNA Molecules to Study DNA Topology and
Topoisomerases by Fluorescence Resonance Energy Transfer.
F. Leng, M. Gu. Florida Intl. Univ.
C10 572.3
Phylogenetic Classification of Gongora
species (Orchidaceae) Based on DNA Barcode Regions matK,
rpoB, rpoC1, and trn-H-psbA C. Guardado, O. Rodriguez, K.
Foss, D. Ludovic, C. Ribadeneyra, C. Trivino, E. Baenziger,
A. Ribes-Zamora, A.D. Simmons. Univ. of St. Thomas, TX.
172
573. DNA DAMAGE SIGNALING
C11
573.1
Characterization of the E. coli SOS Response
Protein YbfE. C. Kramer, M. Muenter, B. Leifer, M. Travers, R.
Judge, P. Beuning. Northeastern Univ.
C12 573.2
Investigating the Metabolism of a Major
Peroxidation DNA Adduct, M1dG, in the Genome. O.R.
Wauchope, W.N. Beavers, J.J. Galligan, M.M. Mitchener, P.J.
Kingsley, L.J. Marnett. Vanderbilt Univ.
C13 573.3
Nuclear Extracts Enzymatically Convert
M1dG to 6-oxo-M1dG in Duplex DNA. M.M. Mitchener, O.R.
Wauchope, L.J. Marnett. Vanderbilt Univ.
C14 573.4
Using Budding Yeast to Study Properties and
Function of the Human Replication Protein A2 N-Terminus in
Response to Specific Types of DNA Damage. S.J. Haring, B.L.
Senger, T.M. Wilson. North Dakota State Univ.
574. DNA REPAIR ENZYMES
Poster
Exhibit Halls A-D
C15 574.1
Investigation of the DNA Damage-Induced
Protein DinD, and Its Effect on DNA Synthesis. Z.J. Romero,
S. Lusetti. New Mexico State Univ.
C16 574.2
Kinetic Mechanism for Binding and Flipping of
Damaged Bases by DNA Repair Dealkylases. P. O’Brien. Univ.
of Michigan.
575. GENOME DIVERSITY AND
DNA RECOMBINATION
Poster
Exhibit Halls A-D
C17 575.1
Novel Gene Identification Using the Transpose
Elements in Rhodococcus aetherivorans Plasmid pR. A3 A.
Alfadda. Alfaisal Univ., Saudi Arabia.
SUNDAYBIOCHEMISTRY
576. GENOME STABILITY AND DNA REPAIR
Poster
C29 578.4
Flexible Modes of Translocation by the
Eukaryotic CMG Helicase Facilitate Removal or Bypass of DNA
Blocks. L.D. Langston, M. O’Donnell. HHMI, Rockefeller Univ.
Exhibit Halls A-D
579. CHROMATIN RECOGNITION AND ASSEMBLY
C18 576.1
Genomic Analysis of the Resistance of E. coli
to Benzyl Bromide. M. Qi, M. Muenter, S. Baig, S. Bellou,
A. Carlson, C. Conway, C. Joshi, C. Kramer, B. Leifer, M.
Travers, P. Wang, R. Giese, P. Beuning. Northeastern Univ.
C19 576.2
Multiple Invasions-Induced Chromosomal
Rearrangements. A. Piazza, W-D. Heyer. Univ. of
California, Davis.
C20 576.3
Mutations in the RQC Domain of Human WRN
Helicase Compromise It’s Ability to Unwind G-Quadruplex
DNA. A. Ketkar, M. Voehler, T. Mukiza, R.L. Eoff. Univ. of
Arkansas for Med. Sci. and Vanderbilt Univ.
C21 576.4
The Influence of Progerin Expression on the
Nature of DNA Double-Strand Break Repair. A.S. Waldman,
S. Chowdhary, A. Patrick, M. Hersey, B.C. Waldman. Univ. of
South Carolina.
C22 576.5
Arabidopsis thaliana: A Unique and Powerful
Model for Genomic Mutation Accumulation and Chromothripsis.
N.L. Fernandes, S. Singh. Univ. of New Hampshire.
C23 576.6
Elucidating the Role of Transcriptional
Mutagenesis in the Acquisition of Adaptive Mutations.
T.T. Saxowsky, G. Wilson, G. Nixon, J. Iverson, P.
Angkanaworakul, C. Brock. Pacific Lutheran Univ.
C24 576.7
The Yeast Genome Project: Characterizing AP.
D1 C. Douds, I. Touimi Ben Jelloun, J.B. Keeney. Juniata
Col., PA.
577. INTERSTRAND CROSSLINK REPAIR
Poster
Exhibit Halls A-D
C25 577.1
Protein-Protein Interaction Inhibitors of the
Fanconi Anemia DNA Repair Pathway. A.F. Voter, K.A.
Manthei, J.L. Keck. Univ. of Wisconsin-Madison.
578. REPLICATION: ALPHA TO OMEGA
Poster
Exhibit Halls A-D
C26 578.1
The Dynamic Nucleotide Selection Mechanism
of DNA Polymerase I at Atomic Resolution. E.Y. Wu, B.R.
Miller, C.A. Parish. Univ. of Richmond.
C27 578.2
Exploration of the Atypical Regions of the
Plasmodium falciparum Apicoplast DNA Polymerase and Their
Potential Role in Antimalarial Drug Discovery. M.E. Milton,
R.B. Honzatko, S.W. Nelson. Iowa State Univ.
C28 578.3
TFAM Mutants Support mtDNA Replication In
Vivo. M. Alexeyev, N. Kozhukhar. Univ. of South Alabama.
Poster
Exhibit Halls A-D
C30 579.1
Heterologous Expression of the Human
Polybromo-1 Protein in the Methylotrophic Yeast Pichia
pastoris S. Hopson, M. Thompson. Michigan Technol. Univ.
C31 579.2
Force Spectroscopy of Nucleosomes at the
Promoters of the LH Genes Reveals Two Distinct Strategies
for Their Regulation. A. Kaplan, S. Rudnizky. Technion - Israel
Inst. of Technol., Haifa.
580. CHROMATIN STRUCTURE IN GENE ACTIVATION
Poster
Exhibit Halls A-D
C32 580.1
Identification and Characterization of Histone
Variant H2A.Z in the Long Terminal Repeat Retrotransposon
Integration. S.K. Rai, Y. Guo, H.L. Levin. NICHD, NIH.
581. DNA METHYLATION DYNAMICS AND FUNCTION
DURING DEVELOPMENT AND PATHOGENESIS
Poster
Exhibit Halls A-D
C33 581.1
Genome Wide Methylation of RASSFs
Associated Genes in Kidney Cancer. M.S. Alokail, A.M. Alenad.
King Saud Univ., Saudi Arabia and Univ. of Southampton, U.K.
C34 581.2
DNA Cytosine Methyltransferase Increases
Stationary Phase Fitness under Temperature Stress in
Escherichia coli R.A. Huss, S. Davidson, K.T. Militello. SUNY
at Geneseo.
C35 581.3
5-Azacytidine Increases Class I HLA ABC
Expression in Tumor Cell Lines. P.L. Long, C.L. Louis, D.W.
Nicholas, R.W. O’Donnell. SUNY Geneseo.
582. DYNAMICS OF TRANSCRIPTION
Poster
Exhibit Halls A-D
C36 582.1
Single-Molecule Analysis of Glucocorticoid
Receptor and Cofactor Action in Living Cells. V. Paakinaho,
D.M. Presman, D. Ball, T.S. Karpova, R.L. Schiltz, P. Levitt,
T. Morisaki, D. Mazza, L.D. Lavis, G.L. Hager. NCI, NIH, Univ.
Vita Salute San Raffaele, Milan and HHMI, Ashburn, VA.
173
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C37 582.2
DNA-Binding Triggers the Tetramerization of
the Glucocorticoid Receptor in Live Cells. D.M. Presman, S.
Ganguly, R.L. Schiltz, T. Karpova, G.L. Hager. NCI, NIH and
Univ. of California, Berkeley.
583. EPIGENOME DYNAMICS IN DEVELOPMENT
Poster
Exhibit Halls A-D
C38 583.1
Identifying the Molecular Mechanisms by
Which Disruptor of Telomere Silencing 1-Like, a Histone 3,
Lysine 79 (H3K79) Methyltransferase, Regulates Mammalian
Hematopoiesis. C. Malcom, J. Piasecka-Srader, N. Alvarez,
C. Slawson, P. Fields. Univ. of Kansas Med. Ctr.
C39 583.2
Decline in Arylsulfatase B and Overexpression
of Galactose 6-Sulfatase Both Increase DNA Methyltransferase
Activity and Wnt Signaling in Prostate Stem Cells. S.
Bhattacharyya, L. Feferman, J.K. Tobacman. Univ. of Illinois
at Chicago and Jesse Brown VA Med. Ctr.
584. FUNCTIONAL CHARACTERIZATION OF CISREGULATORY SEQUENCES
Poster
Exhibit Halls A-D
C40 584.1
Bioinformatics and Electrophoretic Mobility
Shift Assays to Characterize Activators and Repressors of
the Lupinus albus Formamidase Gene. M.C. Amadi, N.P.
Galang, D. Sin, C. Uhde-Stone. California State Univ. East
Bay, Hayward.
C41 584.2
A Genome Editing Approach to Studying
Pmp22 Enhancer Functionality. H. Pantera, J. Moran, C.
Lopez-Anido, J. Svaren. Univ. of Wisconsin-Madison.
585. GENOME-WIDE ANALYSIS
OF TRANSCRIPTIONAL
REGULATORY MECHANISMS
Poster
Exhibit Halls A-D
C42 585.1
Maternal versus Lifelong High-Fat Diet
Differentially Alters Genome-Wide DNA Methylation in Rat
Liver. L. Moody, A. Kriska, H. Chen, Y-X. Pan. Univ. of Illinois
at Urbana-Champaign.
C43 585.2
Molecular Analysis of Adaptational Strategies
under Heat Stress by Whole-Genome Sequencing of
Laboratory-Evolved Saccharomyces cerevisiae A. Satomura,
N. Miura, K. Kuroda, M. Ueda. Kyoto Univ. and Japan Society
for the Promotion of Sci., Kyoto.
174
C44 585.3
Transcriptional Activity of TEAD4 Ensures SelfRenewal of Trophoblast Progenitors during Post-implantation
Placental Development. B. Saha, P. Home, S. Gunewardena,
S. Paul. Univ. of Kansas Med. Ctr.
C45 585.4
The Role of Physical Nano-structure of
Chromatin on Gene Expression. L.M. Almassalha, A. Tiwari,
P. Thusgaard Ruhoff, M. Dela Cruz, H.M. Matsuda, C. White,
Y.M. Stypula-Cyrus, H. Subramanian, I. Szleifer, H. Roy,
V. Backman. Northwestern Univ., Boston Univ. and Univ. of
So. Denmark.
C46 585.5
Steroid Receptors Can Activate Unique FoxA1
Binding Patterns through a Highly Dynamic Mechanism
Associated with a Fast DNA Residence Time. E.E. Swinstead,
T.B. Miranda, V. Paakinaho, S. Baek, M. Hawkins, T. Karpova,
D. Ball, D. Mazza, L.D. Lavis, T. Morisaki, L. Grøntved,
D.M. Presman, G.L. Hager. NCI, NIH, Univ. Vita Salute San
Raffaele, Milan, HHMI, Ashburn, VA and Univ. of So. Denmark.
586. HISTONE MODIFICATIONS
Poster
Exhibit Halls A-D
C47 586.1
Kinetic Studies of Histone Acetylation Effect
in Nucleosome Disassembly Mediated by Histone Chaperone
Na. p1 J.H. Lee, T-H. Lee. Penn State.
C48 586.2
Histones Are Targets for Modification by
Glucose-Derived Methylglyoxal. J.J. Galligan, M.M. Mitchener,
O.R. Wauchope, T. Wang, K.L. Rose, D.A. Spiegel, L.J.
Marnett. Vanderbilt Univ. and Yale Univ.
C49 586.3
Investigating the Structural Dynamics of
Oncogenic Histone Methyltransferases. K.E. Teichert, R.E.
Iacob, T. Wales, J. Paulk, R. St. Pierre, J. Engen, J. Bradner.
Northeastern Univ., Dana Farber Cancer Inst. and Harvard
Med. Sch.
C50 586.4
The Involvement of Histones and Posttranslational Modifications during DNA Repair in Bdelloid
Rotifers. A.C. Jones, M. Ebijoyeldhas, M. Boerma, L.M. Orr,
S.D. Byrum, A.J. Tackett, A.M. Schurko. Hendrix Col. and
Univ. of Arkansas for Med. Sci.
C51 586.5
Quantitative
Histone
H3
Modification
Characterization of Differentiating Hematopoetic Murine
Erythroleukemia Cells Using Parallel Reaction Monitoring
Mass Spectrometry. S. Hess, A. Moradian, M. Raedle, M.
Sweredoski. Caltech and Weihenstephan-Triesdorf Univ. of
Applied Sci., Germany.
C52 586.6
HDAC Inhibitors Decrease p35 Cleavage
through Increased Expression of Calpastatin mRNA in Primary
Neuronal Cells and MPTP-Treated Mice Brain. J. Seo.
Wonkwang Univ., South Korea.
C53 586.7
Comparing the Energetics of Histone Peptide
Binding among Histone Readers. S. Chakravarty, F. Essel, T.
Lin. South Dakota State Univ.
SUNDAYBIOCHEMISTRY
587. NON-CODING RNAS IN GENE REGULATION
AND CHROMOSOME STRUCTURE
Poster
Exhibit Halls A-D
C54 587.1
A Circular RNA ciRS-7 in Alzheimer’s Disease
Targets miRNA-7 Trafficking and Promotes Deficits in the
Expression of the Ubiquitin Conjugase (UBE2A) and the
Epidermal Growth Factor Receptor. W. Lukiw, Y. Zhao, E.
Rogaev, S. Bhattacharjee. LSU Neurosci. Ctr., New Orleans
and Univ. of Massachesetts Med. Sch.
C55 587.2
Analysis of Long Noncoding RNA Chromatin
Interactions by Chromatin Isolation by RNA Purification. N.
Asbrock. EMD Millipore, Temecula, CA.
588. NUCLEAR ARCHITECTURE
Poster
Exhibit Halls A-D
C56 588.1
Chromatin Extrusion Explains Key Features
of Loop and Domain Formation in Wild-Type and Engineered
Genomes. A. Sanborn, S. Rao, S-C. Huang, N. Durand, M.
Huntley, A. Jewett, I. Bochkov, D. Chinnappan, A. Cutkosky,
J. Li, K. Geeting, A. Gnirke, A. Melnikov, D. McKenna, E.
Stamenova, E. Lander, E.L. Aiden. Baylor Col. of Med.,
Stanford Univ. Sch. of Med. and Broad Inst. of MIT and Harvard.
589. TRANSCRIPTIONAL ASSEMBLIES
AND MECHANISMS
Poster
Exhibit Halls A-D
C57 589.1
DNA Breaks and Damage Response Signaling
Are Coupled with RNA Polymerase II Promoter-Proximal Pause
Release and Required for Effective Transcriptional Elongation.
H. Bunch. Harvard Med. Sch., Beth Israel Deaconess Med. Ctr.
590. ALTERNATIVE RNA SPLICING
Poster
Exhibit Halls A-D
C58 590.1
Alternatively Spliced Novel Transcripts of
Mouse Nur77 Gene Identified Using Bioinformatics and
Molecular Biology Techniques. S.R. Abul Kalam, M. Tabish,
M.A. Jairajpuri. Jamia Millia Islamia, New Delhi and Aligarh
Muslim Univ., India.
C59 590.2
Intercellular Transfer of Splicing Factors
via Extracellular Vesicles Promotes Glioblastoma Growth
and Therapy Resistance. M.S. Pavlyukov, A. Mohyeldin,
V.O. Shender, M. Minata, J. Wang, D. Chen, S. Kim, N.V.
Antipova, M.I. Shakhparonov, I. Nakano. Univ. of Alabama
at Birmingham, Shemyakin-Ovchinnikov Inst. of Bioorganic
Chem., Moscow and The Ohio State Univ.
C60 590.3
Identification of Alternatively Spliced Transcript
of Bax Gene in Mouse. M.A. Husain, M. Tabish. Aligarh Muslim
Univ., India.
C61 590.4
Identification and Characterization of a Novel
Alternatively Spliced Isoform of IRF-1 Gene in Mouse. T.
Sarwar, M. Tabish. Aligarh Muslim Univ., India.
C62 590.5
A Novel Alternative Exon of the Caenorhabditis
elegans Lev-11 Tropomyosin Gene Is Used to Express a HeadMuscle-Specific Isoform. D.E. Barnes, H. Kuroyanagi, K. Ono,
E. Kwak, S. Ono. Emory Univ. and Tokyo Med. and Dent. Univ.
C63 590.6
RNA Multifunctional Antisense Gene Transfer
Strategy to Alter Hepatocyte Growth Factor Receptor Expression
in Glioblastoma Multiforme. P. Patel. Monmouth Univ.
C64 590.7
Design of a Pre-trans-Splicing Molecule to
Generate a Soluble Extracellular Peptide Decoy to Block
Activation of the Epidermal Growth Factor Receptor Pathway
in Human Glioblastoma Cells. S.C. Falotico. Monmouth Univ.
C65 590.8
Identification and Characterization of a Minimal
Functional Splicing Regulatory Protein. R.J. Ontiveros,
J. Doan, E.S. Adams, A.L. Hernandez, D.L. Black, N.M.
Keppetipola. California State Univ., Fullerton and UCLA.
591. MOLECULAR RECOGNITION AND
ENZYMOLOGY OF RNA
Poster
S
U
N
Exhibit Halls A-D
C66 591.1
Interactions of a Fluorescently-Labeled
Tobacco Mosaic Virus RNA with Pokeweed Antiviral Protein.
D.J. Rodriguez, A.V. Domashevskiy. John Jay Col.
592. MOLECULAR RECOGNITION OF RNA
Poster
Exhibit Halls A-D
C67 592.1
Characterization of the RNA-Binding Motif
of Phosphoglycerate Kinase 1 – A Moonlighting Function for
a Metabolic Enzyme. A. Walker, K. Friend. Washington and
Lee Univ.
C68 592.2
Analysis of RNA Binding by Evolutionarily
Divergent LARP6 Proteins. J.M. Castro, E. Salas, E. Peña, A.
Kocian, K. Lewis. Texas State Univ. and St. Edward’s Univ.
C69 592.3
Structural and Mechanistic Basis for Self
versus Non-self RNA Discrimination by the Innate Immune
Receptor RIG-I. S. Devarkar, C. Wang, A. Ramanathan, F.
Jiang, M. Miller, A. Khan, J. Marcotrigiano, S. Patel. Robert
Wood Johnson Med. Sch., Rutgers Univ., Piscataway.
175
BIOCHEMISTRYSUNDAY
593. RNA PROCESSING
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C70 593.1
Reprogramming Msl5 to Recognize Mutant
Branch Point Sequences during Spliceosome Assembly. B.
Turner, M. Rodgers, A. Hoskins. Univ. of Wisconsin-Madison.
C71 593.2
Studying the Effects of MDS Mutations
in HSH155 and PRP21 on the Splicing of Introns. G.
Luo, T. Carrocci, D. Zoerner, J. Xu, A. Hoskins. Univ.
C72 593.3
The RS/RGG Domain of the SR-Like Protein
Npl3 Is Required for Efficient RNA Splicing in Yeast. T.L. Kress,
K. Gala, J. Lobby, A. Moazamian, P. Palvannan. The Col. of
New Jersey.
C73 593.4
An Investigation of the Role of the NuA4 and
Swr1 Complexes in Coordination of Transcription and RNA
Splicing. A.N. Avitto, N. Paripati, A. Moazamian, J. Martinez,
R. Moazamian, J. Pleiss, T. Kress. The Col. of New Jersey
and Cornell Univ.
C74 593.5
Histone H3K36 Methylation Is Required for
Efficient Pre-mRNA Splicing in Saccharomyces cerevisiae
D.M. Flood, M.C. Kennedy, M. Sorenson, S. Ucles, D.K. Jha,
B.D. Strahl, S.W. Stevens, T.L. Kress. The Col. of New Jersey,
The Univ. of Texas at Austin and Univ. of North Carolina at
Chapel Hill.
C75 593.6
The Role of Histone Variant H2A.Z in Cotranscriptional Splicing in Saccharomyces cerevisiae L.T.
Neves, S. Douglass, A. Galivanche, T. Johnson. UCLA.
594. RNA: PROCESSING, TRANSPORT, AND
Poster
Exhibit Halls A-D
C76 594.1
Discovery of Mammalian Regulators of
Ribosome Biogenesis. K. Farley, K. McCann, J. Merkel, Y.
Surovtseva, S.J. Baserga. Yale Univ.
C77 594.2
Genetic and Biochemical Studies on the Role
of Essential Protein Dib1 in Pre-messenger RNA Splicing. E.
Bowman, C. Hernandez, C. Schreib, A. Lucas, C. Maeder.
Trinity Univ., TX.
C78 594.3
EWSR1 Potentially Functions as an RNA
Chaperone in the Stress Response. C. Ribadeneyra, S. Amin.
Univ. of St. Thomas, TX.
176
595. PROTEIN SYNTHESIS AND DEGRADATION
C79 595.1
Rheb Inhibits Protein Synthesis by Activating
the PERK-eIF2α Signaling Cascade. R. Tyagi, N. Shahani, L.
Gorgen, M. Ferretti, W. Pryor, P.Y. Chen, S. Swarnkar, P.F.
Worley, K. Karbstein, S.H. Snyder, S. Subramaniam. Johns
Hopkins Univ. Sch. of Med., The Scripps Res. Inst., Jupiter, FL
and Florida Atlantic Univ.
C80 595.2
Translocating Loop-Substrate Interactions
Mediate
Subunit
Coordination
and
Regulate
the
Mechanochemical Coupling and Power Production in a AAA+
Protease Machine. P. Rodriguez, L. Ramirez, F. Kim, C.
Bustamante, A. Martin. Univ. of California, Berkeley.
C81 595.3
Investigating the Mechanism by Which the
Small RNA MtlS Regulates the Mannitol Protein Transporter
at the Post-translational Level in Vibrio cholerae E.E. Hansen,
M.C. Coyle, J.M. Liu. Pomona Col., CA.
C82 595.4
In Vivo Studies of Function of Ribosome
Recycling Factor with Translationally Coupled Two ORFs
Revealed Its Major Function: Release of mRNA from the Posttermination Complex. A. Kaji, Y. Inokuchi, A. Hirashima,
H. Kaji.
Perelman Sch. of Med., Univ. of Pennsylvania, Teikyo Univ.,
Japan and Thomas Jefferson Univ.
C83 595.5
Chemical Ligation Synthesis of IsotopeLabeling Compatible Selenoprotein S. J. Subramoney, Z.
Zhang, R. Cheng, S. Rozovsky. Univ. of Delaware.
C84 595.6
Unraveling the Activation Mechanism of CullinRing Ubiquitin Ligases Using Quantitative Cross-Linking Mass
Spectrometry. C. Yu, H. Mao, E. Novitsky, S.D. Rychnovsky,
N. Zheng, L. Huang. Univ. of California, Irvine and Univ.
of Washington.
C85 595.7
The PINK-Parkin Circuit in Mitochondrial
Quality Control. X. Liu, C. Zhang, Y. Peng, E. Bunker, S. Lee.
Univ. of Colorado Boulder.
596. PROTEASE: STRUCTURE AND REGULATION
Poster
Exhibit Halls A-D
C86 596.1
Modifying Trypsin to Weaken Inhibitor
Interaction. A. Nzessi, H. Huynh, T. Baird. San Francisco
State Univ.
C87 596.2
Optimizing the Enzymatic Activity and Storage
Method of the Metacaspase SUMO-Sc. p3 D.E. Proper, K.M.
Fox. Union Col.
C88 596.3
Adaptor Guided Proteolysis Initiates on the
Ribosome. N. Puri, P. Woo, P. Mehta, A. Choksi, W. Karzai.
Stony Brook Univ.
C89 596.4
Expression and Purification of Active S.
commune Metacaspase Proteins. B.M. Jones, K.M. Fox.
Union Col., NY.
C90 596.5
Decreased Aggregation of Carboxypeptidase
O upon Incorporation into Lipid Rafts. H.O. Ezeribe, L.C.
Burke, G.B. Barfi, P.J. Lyons. Andrews Univ.
SUNDAYBIOCHEMISTRY
C91 596.6
Trypsin as a Model for Investigating Serine
Protease-Inhibitor Interaction. P. Diaz, W. Zhuo, A. Sharma, T.
Baird. San Francisco State Univ.
C92 596.7
Characterization of Ecm14, a Fungal
Pseudopeptidase. T.A. Idowu, M.J. Schott, P.J. Lyons.
Andrews Univ., MI.
C93 596.8
Exploring the Evolution of a Unique Allosteric
Regulatory Mechanism in Caspase-6 R.D. Grinshpon, A.C.
Clark. Univ. of Texas at Arlington and North Carolina State Univ.
597. PROTEASOMES: STRUCTURE
AND REGULATION
Poster
Exhibit Halls A-D
C94 597.1
Assessing Substrate Engagement by Single
Molecules of the AAA+ Protease ClpXP. R.A. Saunders, B.M.
Stinson, R.T. Sauer. MIT.
C95 597.2
Illuminating the Proteasome: Fluorescence
Assays for Investigating the Kinetics of Proteasome Substrate
Processing. J.A. Bard, E. Jonsson, A. Martin. Univ. of
California, Berkeley.
C96 597.3
Mode of Ubiquitination Determines Complete
or Partial Degradation of GFP Substrates by the 26S
Proteasome. G.G. Chirico, D.A. Kraut. Villanova Univ.
C97 597.4
Substrate
Polyubiquitination
Increases
Proteasomal Processivity. E.L. Reichard, W.J. Dewey, N.D.
Nassif, D.A. Kraut. Villanova Univ.
C98 597.5
Conformational Switching in Proteasomal
ATPases Allows for Proper Substrate Processing. A.M.
Snoberger, D.M. Smith. West Virginia Univ.
C99 597.6
Resveratrol Modulates Cytokine Expression
in LPS-Induced Human Monocytes: Role of Proteasome
Subunits. N. Silswal, N. Reddy, N. Qureshi. Univ. of MissouriKansas City.
C104 598.5
Structural Analysis of CCT-Bound Folding
Intermediates for mTORC1 Subunits Raptor and mLS. T8
W.G. Ludlam, T. Aoba, J. Cuéllar, A. Makaju, S. Franklin,
J.M. Valpuesta, B.M. Willardson. Brigham Young Univ.,
Autonomous Univ. of Madrid and Univ. of Utah.
C105 598.6
Structural Characterization of a Mutant Form
of the Chlamydial Protein Pg. p3 T. Trinh, J. Waninger-Saroni,
A. Galaleldeen. St. Mary’s Univ., TX and Univ. of Michigan.
C106 598.7
Hydrodynamic Radius Prediction of Intrinsically
Disordered Proteins. B. Ricard, M. Tomasso, S. Whitten.
Texas State Univ.
C107 598.8
Understanding a Fundamental Force in Protein
Folding: Tuning the n→ π* Interaction via Designed Peptides.
N.A. Wenzell, H.K. Ganguly, A.K. Pandey, G.P..A. Yap, N.J.
Zondlo. Univ. of Delaware.
C108 598.9
Elucidating
ER-Associated
Degradation
Pathway for GABAA Receptors. T. Mu. Case Western
Reserve Univ.
599. REGULATION OF PROTEIN SYNTHESIS BY RNA
Poster
Exhibit Halls A-D
C109 599.1
mRNA Quality Control Is Activated Due to
Chromium (VI) Mediated Oxidative Damage. N. GarciaDoherty, A.L. Larson, M. Six, S.P. Segal. Winona State Univ.
C110 599.2
Translational Regulation of Hypoxia-Inducible
Factor 2α in Response to Iron and Cellular Stressors. W. Lin,
K. Deck, R. Eisenstein. Univ. of Wisconsin-Madison.
C111 599.3
Coaxing a Viral RNA Out of Its Shell: How
Does a Viral RNA Genome Initiate Contact with Its Host? R.W.
Sportsman, C. Beren, B. Kartub, R. Garmann, C. Knobler,
W. Gelbart. UCLA and Harvard Univ. Sch. of Engin. and
Applied Sci.
600. PROTEIN-PROTEIN INTERACTIONS
598. PROTEIN FOLDING AND MISFOLDING
Poster
Exhibit Halls A-D
C100 598.1
Brain Expressed X-Linked 3 Is a HighOrder Oligomer with Partially Folded Regions. K. Cabral, D.
Raymundo, V. Silva, L. Sampaio, L.F. Hill, F. Almeida, Y.
Cordeiro, M. Almeida. Fed. Univ. of Rio de Janeiro.
C101 598.2
Understanding
Dysregulated
Collagen-I
Proteostasis Linked to Osteogenesis Imperfecta. N-D. Doan,
A.S. DiChiara, M.Y. Wong, R.J. Taylor, M.D. Shoulders. MIT.
C102 598.3
Mutational Editing of Strained New Protein
Folds with Deletion Mutations. S.R. Pattengale, V.K. Kumirov,
T.N. Szyszka, M.H.J. Cordes. Univ. of Arizona.
C103 598.4
The Modeling of GroEL to Understand Its
Function. S. Grover, N. Kandru, J. Razo, N. Mendoza, J.
Kenana, I. Dvoretz. Olathe North H.S., Olathe, KS.
Poster
Exhibit Halls A-D
C112 600.1
A Novel Plate-Binding Array to Characterize
CaMKII Protein-Protein Interactions. T.L. Perfitt, C.R. Marks,
R.J. Colbran. Vanderbilt Univ.
C113 600.2
CACN-1 and Its Interacting Proteins
Are Important Regulators of Somatic Development in
Caenorhabditis elegans J. Hugunin. Northeastern Univ.
C114 600.3
Competition between Tamm-Horsfall Protein
and Heparin in Ligand Interactions. M. Haskell, D.C.J. Rhodes.
Pacific Northwest Univ.
C115 600.4
Serum Proteins Binding to Tamm-Horsfall
Protein. H.C. Araujo, D.C.J. Rhodes, J.A. Rhodes. Pacific
Northwest Univ. of Hlth. Sci.
C116 600.5
Binding of Tamm-Horsfall Protein to Properdin
in Various Ionic Environments. J. Morgan, D. Rhodes. Pacific
Northwest Univ.
177
S
U
N
BIOCHEMISTRYSUNDAY
C117 600.6
Determination of the Molecular Interactions
of Bovine Gamma B Crystallins Using NMR Spectroscopy. K.
Mathews, J. Zanet, A. Payan, L. Vacca Michel, G. Thurston,
J. Mills. Rochester Instn. of Technol.
C118 600.7
FRET Analysis of KLHL1 Homo-dimerization
and Interaction with Actin: Influence of CaV3.2 Calcium
Channel Interaction with the KLHL1 Complex. H.R.S. Martin,
V. Sivakumaran, K.A. Benzow, M.D. Koob, J.L. Martin, S.L.
Robia, E.L. Piedras-Renteria. St Johns Univ., NY, Loyola
Univ. Chicago, Maywood and Univ. of Minnesota, Minneapolis.
C119 600.8
Calorimetic Study of Calcium Binding Proteins
with Their Interacting Peptides. C-C. Wei, K. Schaffer, D.
Jensen, R. Ngo. Southern Illinois Univ. Edwardsville.
C120 600.9
Investigating the Activation of the Tm22 Immune Receptor in Response to the Tobamovirus
Movement Protein. C. Sandoval, M.A. Sacco. California State
Univ. Fullerton.
C121 600.10 Computational Design of Helical Peptides
Targeting Transmembrane Domain of Cellular Receptors. H.
Hu, S-Q. Zhang, W.F. DeGrado. Sch. of Pharmaceut. Sci.,
Tsinghua Univ., China, UCSF and Sch. of Arts and Sci., Univ.
of Pennsylvania.
C122 600.11 Calcineurin Homologous Protein Isoforms
1 and 2 Binding to the Sodium Hydrogen Exchanger 1 C.
Marshall, M. Wallert, J.J. Provost. Univ. of San Diego and
Bemidji State Univ.
C123 600.12 Frustrational Analysis of Na+/H+ Exchanger
1 and Calcineurin B Homologous Protein 1 & 2 D. Silva, J.
Latzer, M. Wallert, J.J. Provost. Univ. of San Diego and
Bemidji State Univ.
C124 600.13 Determining Cellular and Viral Interaction
Partners of the Kaposi’s Sarcoma-Associated Herpesvirus
Protein ORF55 K. Randolph, H. Rivas, M.M. Gaglia. St.
Mary’s Univ., TX and Tufts Univ. Sch. of Med.
C125 600.14 Aim32p Is a Novel Member of the Erv1
Translocation Pathway within the Mitochondrial Intermembrane
Space of Saccharomyces cerevisiae D.V. Dabir, K. Nguyen, C.
Koehler. Loyola Marymount Univ. and UCLA.
C126 600.15 Blocking the Protein-Protein Interaction
between Gαh and PLC&Δ1 Inhibits Metastatic Progression in
Triple-Negative Breast Cancer. Y-F. Lin, P-Y. Liu, M. Hsiao.
Col. of Med., Taipei Med. Univ. and Genomics Res. Ctr., Acad.
Sinica, Taipei.
C127 600.16 Analysis of Tectonin I and II and TectoninRelated Proteins from Physarum polycephalum T. Matsuda, R.
Morita, Y. Minami. Okayama Univ. of Sci.
C128 600.17 Juncture of the Cytoskeleton and Innate
Immune Signaling Pathways: The Role of Suppressor of IKK
Epsilon. E.L. Dohleman, H.J. Steele, J.B. Knoblauch, H.A.
Sonnenschein, K.F. Lawrence, J.K. Bell. Univ. of San Diego
and Virginia Commonwealth Univ.
C129 600.18 The Role of Subunit Interfaces of Malate
Dehydrogenase in Protein Folding and Unfolding. J. Abano, E.
Bell, J. Bell. Univ. of San Diego.
C130 600.19 Using ANS to Probe Ligand-Induced
Conformational States of Malate Dehydrogenase. M. Schwabe,
E. Bell, J. Bell. Univ. of San Diego.
C131 600.20 The Effects of the H90 and E256 Mutations in
the gMDH Interface on the Stability, Function, and Interface
Interactions of gMDH. Z. Stewart, N.M. Garcia, E. Bell, J. Bell.
Univ. of Richmond and Univ. of San Diego.
178
C132 600.21 Probing the Subunit Interface of Malate
Dehydrogenase: Effects of S266A and L269A Mutations. N.
James, J. Verdi, E. Bell, J. Bell. Univ. of Richmond and Univ.
of San Diego.
C133 600.22 Transcriptional Complexes Involving PAX3FOX. O1 A. Weatherspoon, T. Cherlin, K. Johanson. Xavier
Univ. of Louisiana.
C134 600.23 FRET Studies Examining the Interaction
of Hepatitis C NS3 Helicase and Human DExD/H Box
Helicases. J. Corby, G. Biener, V. Raicu, D. Frick. Univ.
of Wisconsin-Milwaukee.
C135 600.24 Establishing a Transcription Factors Protein
Network for Lymphangiogenesis: Identification of Binding
Domains, Impact of Pathological Mutations and Perturbations
by Small Molecules. M. Moustaqil, J. Overman, F. Fontaine,
T. Bailey, M. Francois, Y. Gambin, E. Sierecki. Univ. of New
South Wales and Univ. of Queensland.
C136 600.25 Determining Histone Deacetylase 8 Substrates
Using Non-natural Amino Acids. J. Lopez, J. Majmudar, B.
Martin, C. Fierke. Univ. of Michigan.
C137 600.26 Noncanonical PDZ Interaction between
PKAa RIα R368X Acrodysostosis Mutant >and P-Rex1 PDZ
Domain. J.C. Del Rio, J.G.H. Bruystens, L. Chávez-Vargas,
Y. Ma, A.P. Kornev, J. Vázquez-Prado, S.S. Taylor. UCSD and
CINVESTAV-IPN, Mexico City.
C138 600.27 In Vivo Assessment of a Tissue-Engineered
Vascular Graft in a Rat Model. C. MacIsaac, P. Stringa, N.
Lausada, A. Nieponice, J. Vande Geest. Univ. of Arizona and
Fndn. Favaloro, Buenos Aires.
C139 600.28 Novel Protein Binding Kinetics Measurements
in Complex Biological Samples Using AGILE Research. B.
Goldsmith, A. Walker, D. Pan, M. Lerner, F. Barron. Nanomed.
Diagnostics, San Diego.
C140 600.29 Varying Assay of Proteins Vital to Regulation
of the Epithelial Sodium Channel. C. Wolfe, B.E. Roach, R.E.
Booth. Texas State Univ.
601. PROTEOMICS AND BIOINFORMATICS
Poster
Exhibit Halls A-D
C141 601.1
Database for Storage and Rapid Retrieval of
ProMOL Results. C.D. Baker, J.L. Mills, H.J. Bernstein, P.A.
Craig. Rochester Inst. of Technol. Schs. of Life Sci. and Chem.
& Materials Sci.
C142 601.2
Large-Scale
Structure-Based
Prediction
and Identification of Novel Protease Substrates Using
Computational Protein Design. M.A. Pethe, A. Rubenstein,
S.D. Khare. Rutgers and Ctr. for Integrative Proteomics
Res., Piscataway.
C143 601.3
A Group of Novel Serum Diagnostic Biomarkers
for Multidrug-Resistant Tuberculosis by iTRAQ-2D LC-MS/
MS and Solexa Sequencing. C. Wang, C-M. Liu, L-L. Wei,
L-Y. Shi, Z-F. Pan, L-G. Mao, X-C. Wan, Z-P. Ping, T-T. Jiang,
Z-L. Chen, Z-J. Li, J-C. Li. Zhejiang Univ., The Sixth Hosp. of
Shaoxing, Zhejiang Hosp., Hangzhou and The First Hosp. of
Jiaxing, China.
C144 601.4
Identification of the Recognition Sequence in
Gluten by the Prolyl Endoprotease of Eurygaster integriceps S.
Melton. Stephen F. Austin State Univ.
SUNDAYBIOCHEMISTRY
C145 601.5
Mass Spectrometry-Based Proteomic Analysis
of Saliva from Children with Autism Spectrum Disorder and
Matched Controls. K.L. Wormwood, L. Charette, J.P. Ryan,
A.G. Woods, C.C. Darie. Clarkson Univ. and SUNY Plattsburgh.
C146 601.6
Mass Spectrometry-Based Proteomics to
Investigate and Characterize the Jumping Translocation
Breakpoint Protein Using Cancer Cell Lines. D.
Channaveerappa, K. Li, C.C. Darie. Clarkson Univ.
C147 601.7
A Novel Lipolytic Enzyme from an Uncultured
Bacterium Genome. M.V. Rangel, G. Palmieri, N. Zoubeidi, B.
Lee, C. Ouverney. San Jose State Univ. and Univ. of Puerto
Rico, Mayaguez.
C148 601.8
Characterization and Expression of Conserved
Skeletal Proteins in Echinoderms. R.L. Flores, B.T. Livingston.
California State Univ., Long Beach.
C149 601.9
Crystal Structure and Bioinformatics Inferred
Function of Protein A2617 from Methylibium petroleiphilum
A. Saleh, M.J. Collazo, M. Sawaya, D. Cascio, M. Rasche.
California State Univ., Fullerton, UCLA and HHMI, Los Angeles.
C150 601.10 Characterizing the Microbial Sulfur Metabolizing
Community of the Salton Sea Geothermal System. J.Y-H. Lee,
M. Shelton, B. Iglesias, C. Chu, D. Lawrence, E.J. Crane.
Pomona Col., CA.
602. PROTEOMICS/SYSTEMS BIOLOGY FOR
HUMAN HEALTH AND MEDICINE
Poster
Exhibit Halls A-D
C151 602.1
The Human C-Terminome. S. Sharma, O.
Toledo, M. Hedden, K.F. Lyon, S.B. Brooks, R.P. David,
J. Limtong, J.M. Newsome, N. Novakovic, V. Thapar, S.
Williams, S. Rajasekaran, M.R. Schiller. Sch. of Life Sci.,
Univ. of Nevada, Las Vegas, Massachusetts Gen, Hosp. and
Univ. of Connecticut.
C152 602.2
Rapid
and
Reproducible
Proteotype
Acquisition from Biopsy Level Samples. T. Guo, R. Aebersold.
ETH Zurich.
C153 602.3
Noninvasive Biomarker Candidates for
Cadmium-Induced Nephrotoxicity by 2DE/MALDI-TOF MS and
SILAC/LC-MS Proteomic Analyses. A. Moon, S.Y. Kim, H. M.
Lee, E-y. Ko, K.S. Kim, H.S. Kim. Col. of Pharm., Duksung
Women’s Univ. and Sch. of Pharm., Sungkyunkwan Univ.,
South Korea.
C154 602.4
A Novel Immunoassay, AGILE Research,
Enables Detection of Analyte in Quantity Limited Samples. F.E.
Barron, R. Scannura, A.L.P. Tavares, A. Walker, D. Pan, M.
Lerner, D.E. Clouthier, B. Goldsmith. Nanomed. Diagnost.
Inc., San Diego and Univ. of Colorado Anschutz Med. Campus.
603. QUANTITATIVE PROTEOMICS
Poster
Exhibit Halls A-D
C157 603.1
The Potential Urinary Aging Markers from
20-Month-Old Rats. X. Li, Y. Gao. Peking Union Med. Col. and
Beijing Normal Univ.
C158 603.2
New Serum Biomarkers of Blood Coagulation
Function for Pulmonary Tuberculosis Using iTRAQ-Coupled
2D LC-MS/MS. T. Jiang, L-L. Wei, L-Y. Shi, C. Wang, D-D. Xu,
Z-L. Chen, Z-P. Ping, C-M. Liu, J-C. Li. Zhejiang Univ., The
Sixth Hosp. of Shaoxing and Zhejiang Hosp., Hangzhou, China.
C159 603.3
A Preliminary Study on Serum Proteomics in
Yin-Deficiency-Heat Syndrome Rats Using iTRAQ-Coupled
2DLC-MS/MS. C. Liu, L. Mao, Z. Ping, T. Jiang, C. Wang, Z.
Chen, D. Xu, J-C. Li. Zhejiang Univ., China.
604. BIOPHYSICAL METHODS
Poster
Exhibit Halls A-D
C160 604.1
Metal Affinity Chromatography and Protein
Refolding Techniques: Some Observations and Strategies.
O.O. Odunuga, J.M. Weihe, C.N. Tovar. Stephen F. Austin
State Univ.
C161 604.2
Analysis of Fluorescent Proteins for the
Development of an In Vivo System for Protease Evolution. T.L.
Selby. Mercer Univ. Sch. of Med.
C162 604.3
Whole-Blood Optimization of Electrochemical
Biosensors for Biomedical Diagnostics. J. Daniel, M. McCoy,
A.J. Bonham. Metropolitan State Univ. of Denver.
C163 604.4
Inhibition of Osteotropic Breast Cancer Cell
Motility by Zoledronic Acid in a 3D Spheroid Culture. W.A.
Whalen, J.A. Bush. California State Univ., Fresno and UCSF.
605. BIOINORGANIC CATALYSIS
Poster
Exhibit Halls A-D
C164 605.1
Achieving Enzyme-Like Behavior with Amino
Acids and Peptides in the Outer Coordination Sphere of
Hydrogenase Mimics. W. Shaw, N. Borolugodage, A. Dutta.
Pacific Northwest Natl. Lab.
C165 605.2
An Investigation Into the Extended Coordination
Network of Catalytic Zinc Ions in a Class B β-Lactamase. A.
Caruso, E. Eberhardt. Vassar Col., NY.
C166 605.3
Mutagenesis and Steady State Kinetic
Characterization of a Class B Metallo-β-Lactamase. J.P. Baker,
E. Eberhardt. Vassar Col., NY.
179
S
U
N
BIOCHEMISTRYSUNDAY
606. ENZYMES AS DRUG TARGETS
Poster
Exhibit Halls A-D
C167 606.1
Peptide-Induced Inhibition of ATP Synthase
as an Alternative Approach to Combat Microbial Infections. Z.
Ahmad. A.T. Still Univ., MO.
C168 606.2Withdrawn
C169 606.3
A Phosphoglycolate Phosphatase Virulence
Factor from Staphylococcus aureus I. Moreno, S.F. O’Handley.
Rochester Inst. of Technol.
C170 606.4
N-Terminal Domain of Bothrops asper
Myotoxin II Enhances the Activity of Endothelin Converting
Enzyme and Neprilysin. S. Kuruppu, N. Rajapakse, O.
Kleifeld, D.H. Small, J. Whisstock, A.I. Smith. Monash Univ.,
Baker IDI Heart and Diabetes Inst., Prahan and Menzies Res.
Inst., Hobart, Australia.
C171 606.5
Rational Engineering of the CDK9/CyclinT
Complex Improves Protein Stability Enabling Kinetic Analysis
of Inhibitors by SPR. E. Code, A. Ferguson, N. O’Connell, P.
Doig. AstraZeneca R&D Boston.
C172 606.6
Effect of the Heavy Metals Cobalt and
Cadmium on LINE1 Endonuclease Activity. I. Ahmad, M.
Smith, J. Meyers, B. Russell, K. Dorrah, C. DeFreece. Xavier
Univ. of Louisiana.
C173 606.7
Downregulation of the G6PDH Pathway
Can Promote Oxidative Stress-Mediated Reversal of Drug
Resistance in B-Cell Lymphoma Cell Lines. S.H. Mousavifard. Texas A&M Hlth. Sci. Ctr., Bryan.
607. ENZYME INHIBITORS
Poster
Exhibit Halls A-D
C174 607.1
Structural and Inhibitor Screening Studies of a
Fungal Form of Aspartate Semialdehyde Dehydrogenase from
Cryptococcus neoformans G.P. Dahal, R.E. Viola. The Univ.
of Toledo.
C175 607.2
Metallothionein
Induction,
Antioxidant
Defence Systems and Lipid Peroxidation: An Amalgamation
of Biomarkers of Heavy Metals Pollution in Mus musculus F.I.
Osuala, A.A. Otitoloju, M. Igwo-Ezikpe. Univ. of Lagos.
C176 607.3
Functional Studies of Thiosemicarbozone
Compounds against Topoisomerase IIα A.R. Brown, L. Ngo, W.
Morris, W. Medawala, V. Khoo, E. Lisic, X. Jiang. Tennessee
Technol. Univ.
C177 607.4
Inhibitory Effects of Substituted Pyrazoline
Derivatives on Entamoeba histolytica A. Tight, L. Rossi, A.
Espinosa. Roger Williams Univ., MA and RI.
C178 607.5
Topoisomerase
II
Inhibition
by
BZP
Thiosemicarbazones. M.T. Stephens, Y.L. Angulo, R.R.
Eatebarian, W. Medawala, W. Morris, J.E. Deweese, E. Lisic,
X. Jiang. Tennessee Technol. Univ. and Lipscomb Univ.
C179 607.6
Recombinant Production of a PLA2 Inhibitor:
Implications for Production of Venom Inhibitors. H. Elmashhady,
C.Y. Loh, C. Michael, M. Ma, S. Sahudin, V. Schutz. Univ.
of Missouri-Columbia.
180
C180 607.7
Examination of Turnip Mosaic Virus GenomeLinked Protein (VPg) as an Effective Novel Inhibitor of Ricin
Toxin A Chain. S. De Los Santos, A.V. Domashevskiy. John
Jay Col. of Criminal Justice, NY.
C181 607.8
Cloning and Purification of Human Prolyl
Endopeptidase for Biochemical Comparison to Sunn Pest
Prolyl Endoprotease. T.K. Moore. Stephen F. Austin State Univ.
C182 607.9 Development of an Efficient Structure-Based
Drug Discovery Platform for BACE1 Inhibitors for the Treatment
of Alzheimer’s Disease. Y-C. Yen, A. Kammeyer, K.C. Jensen,
A.K. Ghosh, A.D. Mesecar. Purdue Univ.
C183 607.10 Transition-State
Analogs
as
Effective
Inhibitors against Helicobacter pylori 5′-Methylthioadenosine
Nucleosidase. A. Payan, B. Hirsch, V. Schramm. Rochester
Inst. of Technol. and Albert Einstein Col. of Med.
C184 607.11 The Effect of the Heavy Metal Nickel on the
LINE1 Endonuclease. M. Smith, I. Ahmad, J. Meyers, B.
Russell, K. Dorrah, C. DeFreece. Xavier Univ. of Louisiana.
C185 607.12 Identification of Small Molecule Inhibitors of
the LINE1 Endonuclease. J. Meyers, C. DeFreece. Xavier
Univ. of Louisiana.
C186 607.13 Alpha-Glucosidase Inhibitory Activity of
Mormodica charantia P.O. Obih, A. Nguyen, J-C.A. Obih.
Xavier Univ. of Louisiana and So. Univ. at New Orleans.
608. MECHANISTIC STUDIES OF METALLOENZYME
Poster
Exhibit Halls A-D
C187 608.1
Investigation of Solvent Hydron Exchange in
the Reaction Catalyzed by the Antibiotic Resistance Protein,
Cfr. M.R. Bauerle, T.L. Grove, S.J. Booker. Penn State, Albert
Einstein Col. of Med. and HHMI, University Park, PA.
C188 608.2
Structural and Functional Characterization
of the Sco Protein from Thermus hermophilus L. Lopez, L.
Hunsicker-Wang. Trinity Univ., TX.
C189 608.3
Mechanism and Catalytic Potential of a
Cytochrome P450 (OleT) That Catalyzes C-C Bond Scission.
C.H. Hsieh, X. Huang, C.L. Keys, J.T. Groves, R.N. Austin,
T.M. Makris. Univ. of South Carolina, Princeton Univ. and
Barnard Col., Columbia Univ.
C190 608.4
A Surprising Shift in the Biosynthesis of Marine
Meroterpenoids. Z. Miles, S. Deithelm, J. George, B. Moore.
UCSD and Univ. of Adelaide.
C191 608.5
New Insight Into the Role of ATP in Iron
Sulfur Cluster Scaffolding by the Mrp/Nbp35 Family of Cluster
Scaffolds. D.L. Perlstein, J. Grossman. Boston Univ.
SUNDAYBIOCHEMISTRY
609. PHOTOCHEMICAL SENSORS
612. CHEMICAL BIOLOGY AND DRUG DISCOVERY
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C192 609.1
Effects
of
Antisense
Oligonucleotide
Treatment on Photoreceptor Function in a Mouse Model of
Usher Syndrome. F.A. Franceschini, R. Amato, F. Rigo, M.
Hastings, J. Lentz. LSU Hlth. Sci. Ctr., New Orleans, Univ.
of Puerto Rico, Ponce, Isis Pharmaceut. Inc., Carlsbad and
Rosalind Franklin Univ. of Med. and Sci.
610. PROTEIN INTERACTIONS IN CATALYSIS
Poster
Exhibit Halls A-D
C193 610.1
Potential Electron Transfer Protein Complexes
during the Initiation of Polychlorinated Biphenyl Degradation
Investigated by Small-Angle X-Ray Scattering. C. Colbert,
J. Jensen, B. LeVahn, Z. Staskywicz, K. Glover, D. Neau,
S. Chakravarthy, S. Sinha. North Dakota State Univ., North
Eastern Collab. Access Team, Fargo and Biophysics Collab.
Access Team, Argonne, IL.
C194 610.2
Systematic Proteomics and Biochemical
Approaches to Identifies the Function of UBXN10 in p97Associated Process. X. Li, S. Li,T-F. Chou. LA BioMed, Torrance.
611. PROTEOLYTIC ENZYMES AND INHIBITORS
Poster
Exhibit Halls A-D
C195 611.1
Cleavage of Proglucagon by the Prohormone
Converting Enzymes PCSK1 and PCSK2 Is Not Dictated by the
Amino Acid Sequence Immediately Adjacent to the Cleavage
Site. R.B. Mackin. Creighton Univ.
C196 611.2
Peptides Mimicking the Reactive Center Loop
as Potential Inhibitors of Serpin-3 in Manduca sexta M. Li, M.R.
Kanost. Kansas State Univ.
C197 611.3
N-Terminal Extracellular Beta-1 Adrenergic
Receptor Cleavage by Matrix Metalloproteinase 2 A.N.
Gonçalves, J. Ramos, R.F. Gerlach. Univ. of São Paulo,
Ribeirão Preto.
C198 611.4
Insights into Rate-Limiting Substrate Dynamics
during Proteolysis of Kunitz-BPTI Family Canonical Serine
Protease Inhibitors. O. Kayode, T.R. Caulfield, A. Soares,
E.S. Radisky. Mayo Grad. Sch., Col. of Med. and Cancer Ctr.,
Jacksonville, FL and Brookhaven Natl. Lab.
C199 612.1
A New Oridonin Analogue Suppresses TripleNegative Breast Cancer Cells and Tumor Growth via Inducing
the Expression of Death Receptor 5 C. Chen, J. Wu, J. Zhou.
Kunming Inst. of Zoology, CAS, China and Univ. of Texas
Med. Branch.
C200 612.2
Menaquinone Biosynthesis: An Antibacterial
Target? J. Matarlo. Stony Brook Univ.
C201 612.3
Chemical and Chemoenzymatic Synthesis
of UDP-N-Acetyl Glucosamine Probes. T.K. Heiss, K.E.
DeMeester, H. Liang, B. Barbero, C. Leimkuhler Grimes.
Univ. of Delaware.
C202 612.4
Synthesis of Artificial Bacterial Cell Wall
Fragments as Tools to Study the Innate Immune System.
G. Gregorzak, J. Melnyk, K. DeMeester, C. Grimes. Univ.
of Delaware.
C203 612.5
A Lipid Fraction from Catfish (Arius bilineatus,
Val.) potently Inhibits Collagen-Induced Aggregation In Vitro.
C. Pace-Asciak, J.M. Al-Hassan, M. Afzal, B.M. Paul, S.
Oommen, Y.F. Liu. Univ. of Toronto Hosp. for Sick Children
(SickKids), Kuwait Univ. and CMS Col. Kottayam, India.
C204 612.6
Anti-Inflammatory, Anti-Proliferative Activities
from the Skin of the Catfish arius Bilineatus, Valenciennes P.
Yang, J. Ding, L. Tang, P. Rhea, Y. Pan, M. Afzal, B.M. Paul,
S. Oommen, J.M. Al-Hassan. Univ. of Texas MD Anderson
Cancer Ctr., Kuwait Univ., Kuwait and CMS Col., India.
C205 612.7
Structural Insight into Glucose-6-Phosphate
Dehydrogenase (G6PD) Deficiency – Discovery of Novel
G6PD Activators to Correct G6PD Deficiency. S. Hwang.
Stanford Univ.
C206 612.8
Cell-Rounding Compounds Inhibit Components
of the Bacterial Cytoskeleton. M. Lammers, T. Santos, K.
Hurley, T. Mitchinson, D. Weibel. Univ. of Wisconsin-Madison
and Harvard Med. Sch.
C207 612.9
Progress towards Design of a Light Activated
COX-2 Inhibitor. W. Paulishak, C. Armstrong, M. DeBerardino,
C. Rous, P. Mertz, C. Streu. St. Mary’s Col. of Maryland and
Albion Col., MI.
C208 612.10 The First Example of Allosteric Partial Inhibition
of a Monomeric Protease. S. Verespy, A.Y. Mehta, D. Afosah,
R.A. Al-Horani, U.R. Desai. Virginia Commonwealth Univ.
C209 612.11 Search for New Pro-apoptotic Agents in
Indigenous Antitumor Plants in Nigeria. A.B. James, G.M.
Saibu, O.A. Magbagbeola, S.A. Omilabu, M. Meyer. Col. of
Med., Univ. of Lagos, Lagos State Univ., Nigeria and Univ. of
the Western Cape, South Africa.
C210 612.12 Evolution of Metal Ion and Purine Nucleotide
Effects and Cooperativity in Glutamate Dehydrogenase: The
Role of Conformational Flexibility. S. Tran, J. Bell, E. Bell. Univ.
of San Diego.
C211 612.13 Effects of Purine Nucleotides on the Stability
of Glutamate Dehydrogenase Studied Using a Fluorescence
Based Thermal Shift Assay. A. Smith, J. Bell, E. Bell. Univ. of
San Diego.
181
S
U
N
BIOCHEMISTRYSUNDAY
C212 612.14 A Fluorescent, HTS-Adaptable CoupledEnzyme Assay for Measurement of Human Cytosolic
Sulfotransferase 2B1b Activity and Identification of SmallMolecule Inhibitors. Q. Zhou, A. Mesecar. Purdue Univ.
C213 612.15 Synthesis of a New Series of Alpha-(N)Heterocyclic Thiosemicarbazone Ligands and Their Cu2+, Pd2+,
and Pt2+ Metal Complexes: Differences in Biological Activity.
V.G. Rand, E. Lisic. Tennessee Technol. Univ.
C214 612.16 Conjugation of BSA Onto PEG8 via StrainPromoted Azide-Alkyne Cycloaddition as a Drug Delivery
System. J. Hill. Loyola Univ. Chicago.
C215 612.17 Imaging Withaferin A-Vimentin Interactions
in Live Cells and Fibrotic Tissues. P. Bargagna-Mohan, S.
Keshipeddy, D.L. Wright, R. Mohan. Univ. of Connecticut
Hlth. Ctr. and Univ. of Connecticut.
C216 612.18 Synthesis and Biological Evaluation of
10-Chloro-9h-5-oxa-6b,7,9,11,12-pentaaza-benzo[5,6]
pentaleno[2,1-b]naphthalen-6-one. S. Govori, A. Haziri, N.
Neziraj, H. Ibrahimi. Univ. of Pristina, Albania.
C217 612.19 Novel Allosteric Destabilizers as Therapeutics
for Genetic Diseases and Trauma. J.C. Groppe, G. Lu, A.
Dawson, T. Dawson. Texas A&M Baylor Col. of Dent.
613. NEW TARGETS FOR DRUG
DISCOVERY: ANTIBACTERIALS
Poster
Exhibit Halls A-D
C218 613.1
Biophysical and Structural Studies of Chelator
Fragment-Library Candidates as Inhibitors of Metallo-βlactamases. C. Williams, D.L. Tierney, M.W. Crowder, S.
Cohen, W. Fast, R.C. Page. Miami Univ., UCSD and Col. of
Pharm., Univ. of Texas at Austin.
C219 613.2
Antibacterial Activity of Organic Ligands and
Their Cu(II) Complexes. S. Hamaway, K. Fox, J. Tanski, L.
Tyler. Union Col. and Vassar Col.
C220 613.3
Elucidating the Molecular Basis of Protein
and Polymer Display in Pathogenic Bacteria for Novel Antivirulence Drug Development. M. Kattke, M. Sawaya, D.
Cascio, A. Duong, M. Elliot, R. Clubb. UCLA and McMaster
Univ., Canada.
C221 613.4
Synthesis and Application of Small Cationic
Hexamers as Potential Antibiotic Agents. J.W. Sheffield, C.T.
Kyle, J.D. Rockenbach, C.W. Anderson, M.J. Wolyniak.
Hampden-Sydney Col., VA.
C222 613.5
Cell Membrane Permeabilization by Double,
Bi-monopolar and Bi-polar, Electrical Pulses and Polycationic
Peptides. V.V. Lemeshko, D.A. Ortiz. Natl. Univ. of
Colombia, Medellin.
C223 613.6
Investigating Mycobacterium tuberculosis
L,D-Transpeptidases as Novel Drug Targets. L. Basta, Y. Pan,
A. Kaushik, E. Lloyd, C. Townsend, B. Staker, C. Lukacs,
M. Bianchet, G. Lamichhane. U.S. Naval Acad., Annapolis,
Johns Hopkins Univ. Sch. of Med., Johns Hopkins Univ., Ctr.
for Infect. Dis. Res., Seattle and Elpedira, Cambridge, MA.
C224 613.7
Development of Novel Small Molecule
Antibiotics against T-Box Riboswitches in Gram-Positive
Bacteria. V.Y.P. Väre, G.C. Todd, K.M. Frohlich, J.T. Bell, S.F.
Weintraub, P.F. Agris. SUNY at Albany.
182
C225 613.8
Fine-Tuning the Selectivity of Pore-Forming
Peptides From Loss-of-Function High Throughput Screening.
A.J. Krauson, M. Hall, T. Fuselier, C.G. .Starr, W.B. Kauffman,
W.C. Wimley. Tulane Univ.
C226 613.9
Camel VHH for the Prevention of Listeria
monocytogenes cellular Invasion. M. Toride, I. Huh, M.
Mendoza, C.L. Brooks. California State Univ., Fresno.
614. NEW TARGETS FOR DRUG DISCOVERY:
SIGNALING PROTEINS
Poster
Exhibit Halls A-D
C227 614.1
Mechanisms by Which Plant Extracts Delay
Aging in Yeast by Targeting Certain Signaling Pathways and
Modulating Lipid Metabolism. V. Titorenko, V. Lutchman,
Y. Medkour, A. Leonov, A. Arlia-Ciommo, V. Svistkova, P.
Dakik. Concordia Univ., Montreal.
C228 614.2
Small Molecule Activation Affects Cellular
Localization of NF&κB and Fox03 during LPS-Induced TLR4
Signaling. R.A. Day, D. Stoub, V. Gupta. Dordt Col, IA and
Rush Med. Sch.
615. WELCOME TO THE POST-ANTIBIOTIC ERA
Poster
Exhibit Halls A-D
C229 615.1
Acetylating Polymyxin Antibiotics: Clues
toward Substrate Specificity of PA3944 Gcn5-Related
N-Acetyltransferase of Unknown Function. M.L. Kuhn, L. Joe,
B. Amsler, B. Zhang, K. Majorek, R. Yen, W. Wu, G. Gassner,
T. Baird, W. Minor. San Francisco State Univ. and Univ.
of Virginia.
616. GLYCOSCIENCE IN BIOLOGY
Poster
Exhibit Halls A-D
C230 616.1
Hyaluronan Signals Release and Nuclear
Accumulation of WWOX and Smad from Membrane Hyal-2
N-S. Chang. Natl. Cheng Kung Univ., Taiwan.
C231 616.2
A New Selective Probe for Visualization and
Identification of O-GlcNAc-Modified Proteins in Cells. P.G.
Wang, J. Li, J. Wang, L. Wen, S. Li, H. Zhu, C. Ma, X. Li.
Georgia State Univ. and Col. of Pharm., Nankai Univ., China.
C232 616.3
Cell-Specific
Glycomic
and
Signaling
Alterations Associated with Human Ganglioside Deficiency. M.
Dookwah, K. Aoki, M. Kulik, S. Dalton, R. Steet, M. Tiemeyer.
Univ. of Georgia.
SUNDAYBIOCHEMISTRY
617. REGULATION OF GENE EXPRESSION
BY O-GLCNAC
Poster
Exhibit Halls A-D
C233 617.1
Dynamic Interactions of TATA-Box Binding
Protein with Promoters Is Regulated by O-GlcNAcylation. S.
Hardivillé, G. Han, J. Ma, P. Hu, P.S. Banerjee, G.W. Hart.
Johns Hopkins Univ. Sch. of Med.
618. GLYCANS IN BACTERIA
Poster
621. GLYCANS IN PROTEIN QUALITY CONTROL
Poster
Exhibit Halls A-D
C239 621.1
GRP78 Is Not Expressed on the Surface of
Triple Negative Human Breast Cancer Cells. J.E. SerranoNegron, E.C. Romero, N. Sanchez, A. Banerjee, K. Baksi,
D.K. Banerjee. Univ. of Puerto Rico, San Juan, Univ.Central
del Caribe, Bayamón and Inst. of Funct. Nanomaterials, San
Juan, PR.
622. GLYCOBIOLOGY AND
EXTRACELLULAR MATRIX
Exhibit Halls A-D
Poster
Exhibit Halls A-D
C234 618.1
N-Linked Glycosylation of Hemagglutinin
Globular Head Modulates the Antibody Response to H3N2
Influenza A Virus. I. Alymova. Ctrs. for Dis. Control and Prevent.
C235 618.2
Glycans in Pseudomonas aeruginosa A.K.
McClinton, D.L. Cioffi, E.A. Cioffi. Univ. of South Alabama.
619. GLYCANS IN DEVELOPMENT
Poster
Exhibit Halls A-D
C236 619.1
The Role of N-Linked Glycosylation in
Drosophila Development Morgan Thomas and Dr. Erica
M. Selva Department of Biological Sciences, University of
Delaware, 210 South College Ave, Newark, Delaware 19711
M.D. Thomas, E.M. Selva. Univ. of Delaware.
620. GLYCANS IN DISEASE
Poster
Exhibit Halls A-D
C237 620.1 Lectin-Like Properties of Human Antibodies
against the Red Meat-Derived Antigen N-Glycolylneuraminic
Acid: A Mitogenic Factor Promoting Carcinoma Growth. F.A.
da Silva, N. Nguyen, A. Varki. UCSD.
C238 620.2
Downregulating FUK to Get Unstuck: Altered
Fucosylation in Melanoma Promotes Tumor Development and
Metastasis. E.K. Lau, Y. Feng, G. Claps, M.N. Fukuda, A.
Perlina, D. Donn, L. Jilaveanu, H. Kluger, H.H. Freeze, Z.A.
Ronai. Moffitt Cancer Ctr., Tampa, Sanford Burnham Prebys
Med. Disc. Inst., La Jolla and Yale Univ.
C240 622.1
MAGP2 Binding to αvβ3 Integrins Affects Levels
of Microfibril Formation. R. Daniels, M. Valdivia, A. Perez, A.
Miyamoto. California State Univ. Fullerton.
C241 622.2
Bioengineering Proteoglycan-Based Matrices
for Blood Contacting Applications. M. Lord, C. Chuang, J.
Rnjak-Kovacina, B. Cheng, G. Lyons, J. Whitelock. Grad.
Sch. of Biomed. Engin., Univ. of New South Wales, Univ. of
Copenhagen, Sydney Med. Sch., Royal Prince Alfred Hosp.,
Univ. of Sydney and Sydney Head and Neck Cancer Inst.
S
U
N
623.GLYCOMICS
Poster
Exhibit Halls A-D
C242 623.1
Cellular O-Glycome Reporter/amplification
to Explore O-Glycans of Living Cells. M.R. Kudelka, A.
Antonopoulos, Y. Wang, D.M. Duong, X. Song, N.T. Seyfried,
A. Dell, S.M. Haslam, R.D. Cummings, T. Ju. Harvard Univ.,
Imperial Col. London and Emory Univ.
624.GLYCOSYLTRANSFERASES
Poster
Exhibit Halls A-D
C243 624.1
Dysregulation of TGF-β Signaling: A Key Role
for Fucosyltransferase-1 in Scleroderma and BleomycinInduced Fibrosis. W.A. Stinson, P-S. Tsou, N. Lepore, S.
Arwani, G. Edhayan, R. Ohara, E. Cealey, B.J. Rabquer, D.
Khanna, D. Fox, M.A. Amin. Univ. of Michigan Med. Ctr. and
Albion Col.
C244 624.2
Investigation of Enzymatic Mechanism and
Cellular Expression of DPY-19L1 and DPY-19L4 A. Kastigar,
B. Murdock, J. Rakus. Marshall Univ.
183
BIOCHEMISTRYSUNDAY
C245 624.3
Regulation
of
Notch
Signaling
by
O-Glucosylation:
Notch-Modifying
XylosyltransferaseSubstrate Complexes Support an SNi-Like Retaining
Mechanism. R.S. Haltiwanger, H. Yu, M. Takeuchi, J.
LeBarron, J. Kantharia, E. London, H. Bakker, H. Li, H.
Takeuchi. Univ. of Georgia, Brookhaven Natl. Lab., NY, Stony
Brook Univ. and Hannover Med. Sch., Germany.
C254 626.5
Transcriptomic and MicroRNA Analyses
Identify Gene Networks Regulated by Eicosapentaenoic Acid
in Brown Adipose Tissue from Diet-Induced Obese Mice. M.
Pahlavani, N.N. Wijayatunga, R. Kottapalli, L. Ramalingam,
P.H. Gunaratne, C. Coarfa, K. Rajapakshe, N.S. Kalupahana,
N. Moustaid-Moussa. Texas Tech Univ., Univ. of Houston and
Baylor Col. of Med.
625. AGING AND METABOLISM
627. METABOLISM, DISEASE AND DRUG DESIGN
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C246 625.1
Plasma Kallistatin Is Associated with
Leukocyte Telomere Length in Young African Americans. H.
Zhu, J. Chao, A. Raed, Y. Huang, J. Bhagatwala, S. Parikh, Y.
Dong. Med. Col. of Georgia, Augusta Univ. and Med. Univ. of
South Carolina.
C247 625.2
Regular
Supplementation
of
Dietary
Compounds Modulates Longevity and Aging in Drosophila
melanogaster L. Holohan, R.P. Rogers. Wentworth Inst. of
Technol., Boston.
C248 625.3
Indices of Fatty Acyl-CoA Desaturase Activity
Are Associated with Cognitive Function and Preclinical
Changes in Cerebrospinal Fluid Beta-Amyloid and Tau Levels
in Alzheimer’s Disease. A.N. Fonteh, M. Cipolla, J. Chiang, X.
Arakaki, M. Harrington. HMRI, Pasadena.
C249 625.4
Detection of Glycerophospholipids and
Sphingolipids in Urine and Their Correlation with Cerebrospinal
Fluid Beta-Amyloid 42 A.N. Fonteh, M. Cipolla, J. Chiang, K.
Castor, M. Harrington. HMRI, Pasadena.
626. GENETIC AND METABOLIC APPROACHES
TO OBESITY
Poster
Exhibit Halls A-D
C250 626.1
Genomic Analysis of Obesity Gene Risk
Variations: Understanding the Thrifty-Genotype Hypothesis
on an Evolutionary Time-Scale. J.J. Castillo, Z. Hazlett, W.S.
Garver. Univ. of New Mexico.
C251 626.2
Adipose
Depot-Specific
Differences
in
Transcriptome and MicroRNA Expression in High Fat DietInduced Obese Mice. N.N. Wijayatunga, M. Pahlavani, R.
Kottapalli, J.A. Dawson, L. Ramalingam, P.H. Gunaratne,
C. Coarfa, K. Rajapakshe, N.S. Kalupahana, N. MoustaidMoussa. Texas Tech Univ., Univ. of Houston, Baylor Col. of
Med. and Univ. of Peradeniya, Sri Lanka.
C252 626.3
Do Sweeteners Affect the Expression of (Pro)
renin Receptors in the Rat Kidney? N.E. Young, T. Salerno.
Minnesota State Univ., Mankato.
C253 626.4
Modulation of Hypothalamic Activity Alters
Appetite in a Novel Antioxidant Mouse. D.L. Amos, L. Efaw,
C. Cook, M. Massie, N. Mitchell, A. Gudivada, N. Santanam.
Marshall Univ. and Bluefield State Col., WV.
184
C255 627.1
Affinity of Prostate Specific Membrane Antigen
for Synthetic N-Acetylaspartylglutamate Derivatives. K. Javed,
L. Salamanca Cardona, K. Keshari. St. John’s Univ. and
Mem. Sloan Kettering Cancer Ctr.
C256 627.2
Exploration of Plasmodium Kinases. A.L.
Eubanks, E.R. Derbyshire. Duke Univ.
C257 627.3
Administration of a Novel β-Hydroxybutyrate
Ester after Radiation Exposure Suppresses In Vitro Lethality
and Chromosome Damage, Attenuates Bone Marrow
Suppression In Vivo. M.F. Kemper, A. Miller, R.J. Pawlosky,
R. Veech. NIAAA, NIH, Rockville and Armed Forces Radiobiol.
Res. Inst., Bethesda.
C258 627.4
Evaluation of Compounds That Inhibit Fatty
Acid Uptake in Mice. S. Taylor, N. Saini, D. Montefusco, P.
Black, C. DiRusso. Univ. of Nebraska-Lincoln.
C259 627.5
Novel Method for the Detection of Glucose
Uptake: Direct Measurement of Glucose Levels in Cultured
Cells. K. Yan, S. Li, Y. Lin, S. Saddar, G. Tchaga, G. Yan.
BioVision Inc., Milpitas, CA and Henry M. Gunn H.S., Palo Alto.
C260 627.6
Small Fungal Molecule Metabolites Targeting
Mosquito Midgut FREP1 Block Malaria Transmission. J. Li.
Univ. of Oklahoma.
C261 627.7
Characterizing the Structural Requirements
of the Human Antiviral Protein Apobec3G. R. Casazza, A.
Sheehy. Col. of the Holy Cross, MA.
C262 627.8
Expression Profile of Monocarboxylate
Transporters and Basigin Gene Products in the Mouse
Cornea. R.G. Maniccia, J.D. Fong, J.D. Ochrietor. Univ. of
North Florida.
C263 627.9
Analysis of Immune Molecule Expression
in Mouse Adipose Tissue and Deep Fat. S. Juresic, J.D.
Ochrietor. Univ. of North Florida.
C264 627.10 In Good Taste: An Investigation of Lactate
Metabolons in the Mouse Tongue. J.D. Ochrietor, H. Zahir, L.
Castillo, R. Seddeik, J.D. Gelsleichter. Univ. of North Florida.
C265 627.11 Characterization of Basigin and MCT1
Expression in Murine Myocardium. G.E. Morse, J.D. Ochrietor.
Univ. of North Florida.
SUNDAYBIOCHEMISTRY
628. METABOLISM AND NUTRITION
Poster
Exhibit Halls A-D
C266 628.1
Association of Serum Sex Hormone-Binding
Globulin with Features of Metabolic Syndrome in Children. N.
Al-Daghri, N. Khan, O. Al-Attas, S. Sabico, M. Alokail, S.
Kumar. King Saud Univ. and Warwick Univ., U.K.
C267 628.2
High Fructose Corn Syrup-55 Alters Hepatic
Metabolism to Increase Risk of Non-alcoholic Fatty Liver
Disease in Female Sprague-Dawley Rats. S. Lateef, K. Mock,
V. Benedito, J. Tou. West Virginia Univ.
C268 628.3
Parental Diet Modulates Gene Expression in
Drosphila melanogaster J. Tresser. Biola Univ., CA.
C269 628.4
Variation in Inositol Utilization in Closely
Related Drosophilids. M.B.T. Smith, E. Eldon, L. Klig.
C270 628.5
Contribution of Poly-unsaturated Fatty Acids
on Cerebral Neurobiology: An Integrated Omics Approach with
Epigenomic Focus. N. Chakraborty, S. Muhie, A. Gautam,
R. Hammamieh, M. Jett. U.S. Army Ctr. for Enfrn. Hlth. Res.,
Frederick, MD.
C271 628.6
The Roles of GPD1 in Maintaining Blood
Glucose Levels under Fasting Conditions. T. Sato, A. Morita,
N. Mori, S. Miura. Univ. of Shizuoka and Osaka Prefect.
Univ., Japan.
C272 628.7
Antioxidant Activity of Three Local Leafy
Vegetables of Western Uganda. H.W. Kinyi, W. Byarugaba, M.
Vicente-Crespo. Kampala Intl. Univ. and Kabale Univ., Uganda.
C273 628.8
The Role of 12/15-Lipoxygenase in a Mouse
Model of Alcoholic Liver Disease. I. Kirpich, M. Miller, C.
Ramsden, A. Feldstein, C. McClain. Univ. of Louisville,
NIAAA, NIH, UCSD and Robley Rex VA Med. Ctr., Louisville.
C274 628.9
Blueberry
Supplementation
Attenuates
Oxidative Stress within the Monocytes and Modulates Immune
Cell Levels in Adults with Metabolic Syndrome. A.R. Nair, N.
Mariappan, A.J. Stull, J. Francis. LSU Sch. of Vet. Med. and
Pennington Biomed. Res. Ctr.
C275 628.10 Location of Iron and Ferritin in the Midgut of
the Yellow Fever Mosquito, Aedes aegypti M.B. Love, D.L.
Geiser, J.J. Winzerling. Univ. of Arizona.
629. OMICS APPROACHES TO TARGET DISCOVERY
Poster
Exhibit Halls A-D
C276 629.1
Metabolomics
Reveals
the
Glycerophosphodiester Phosphodiesterase GDPD5 to
Regulate an Invasive Phenotype in Lung Cancer Cells and
Potentially Constitute a Novel Drug Target. A. Nordstrom, O.
Broom, B. Witek. Umea Univ., Sweden.
C277 629.2
Signaling Pathways Activated during Acute
Aldosterone Stimulation in Kidney Distal Convoluted Tubule
Cells. L. Cheng, Q. Wu, L. Peng, T. Pistikun, R. Fenton.
Aarhus Univ., Denmark and Chulalongkorn Univ., Thailand.
C278 629.3
Development of a Python-Based Algorithm
for Comparative Analysis of Multiparticipant Next Generation
Sequencing Data. F.G. Martz, T.M. Forst, S.M. Ryan, P.J.M.
Murphy. Seattle Univ.
C279 629.4
Development of a Python-Based Algorithm for
the Quantification and Analysis of Multivariate Next Generation
Sequencing Data following Genome-Wide Mutagenesis
and Cell Survival Screening. T.M. Forst, P.J.M. Murphy.
Seattle Univ.
630. NUCLEAR RECEPTORS IN
METABOLIC SYNDROMES
Poster
Exhibit Halls A-D
C280 630.1
Effects of Synthetic Ligands on Heterodimer
Pairs Regarding PPARα, RXRα and LXRα E.E. Delman, S.D.
Rider, H.A. Hostetler. Wright State Univ.
C281 630.2
Critical Role of Residues in Helices 9 and 10 of
the Liver X Receptor Alpha in Mediating Heterodimer Choice
between Heterodimeric Complexes. S. Bedi, H.A. Hostetler,
S.D. Rider; Jr. Wright State Univ.
C282 630.3
Characterization of the Functional Significance
of PPAR/LXR Heterodimers via a Novel Response Element.
A.M. Klingler, S.D. Rider, H. Hostetler. Wright State Univ.
C283 630.4
Development and Characterization of Dual-Site
PPAR&γ Antagonists. R. Brust, A. Asteian, T. Kamenecka, D.
Kojetin. Scripps Florida.
C284 630.5
Nuclear
Receptor
SHP
Reduces
Proinflammatory Macrophage Polarization in High FatCholesterol-Fructose Diet-Induced Mouse Model of Nonalcoholic Steatohepatitis. N. Magee, A. Zou, S. Lehn, Y. Zhang.
Kansas Univ. Med. Ctr.
631. CARGO SORTING AND VESICLE TARGETING
Poster
Exhibit Halls A-D
C285 631.1
A Novel Element in the Cytoplasmic Domain of
the Type I TGFβ Receptor Mediates Basolateral Targeting in
Polarized Epithelial Cells. X. Yin. Mayo Clin.
C286 631.2
Novel Cell-Penetrating Peptides Overcome
Endosomal Escape and Deliver Protein Cargos Into the Cell.
V. Ngwa, J. Salerno, S. Nowak, C. Chrestensen, J. McMurry.
Kennesaw State Univ.
C287 631.3
The Roll of COMMD1 in Membrane Protein
Trafficking. D. Stewart, K. Short, E. Buglo, J. Burkhead. Univ.
of Alaska Anchorage.
185
S
U
N
BIOCHEMISTRYSUNDAY
632. CELL MIGRATION
Poster
Exhibit Halls A-D
C288 632.1
Coiled-Coil Domain Containing Protein 103
Regulates Myeloid Development and Function. S. Beckman,
J. Waxman. Cincinnati Children’s Hosp. Med. Ctr.
C289 632.2
HMG Box-Containing Protein 1 Modulates
Matrix Metalloproteinase-13-Mediated Cellular Migration and
Invasion in Oral Cancer. C.Y. Chan, W-C. Wu, T-Y. Lin, M-F.
Lee, C-Y. Huang. China Med. Univ. and Chang Jung Christian
Univ., Taiwan.
C290 632.3
Secreted Factors, Identified as Exosomes,
Enhance Proliferation, Migration, and Invasion in MDA-MB-231
Cells. T. Cunningham, L.A. Yearby, D. Garrett, K.P. Lemieux.
Xavier Univ. of Louisiana.
C291 632.4 PLCβ3 Mediates Cortactin Interaction with
WAVE2 in MCP1-Induced Actin Polymerization and Cell
Migration. J. Janjanam, G.K. Chandaka, S. Kotla, G.N. Rao.
Univ. of Tennessee Hlth. Sci. Ctr., Memphis.
633. CELL SIGNALING, KINASE
AND CHEMOTHERAPY
Poster
Exhibit Halls A-D
C292 633.1
Effect of Cinobufotalin on Three Different
Ovarian Cancer Cell Lines. S.H. Afroze, R. Tobin, C.
Peddaboina, T.C. McCormick, M. Newell-Rogers, D.C.
Zawieja, T.J. Kuehl, M.N. Uddin. Texas A&M Hlth. Sci. Ctr.
Col. of Med. and Baylor Scott & White, Temple, TX.
C293 633.2
Hematopoietic TAK1 Is Required for
Maintaining Lysosomal Integrity and Cell Survival in Resident
Macrophages. Y. Sakamachi, S. Mihaly, S. Morioka, J.
Ninomiya-Tsuji. North Carolina State Univ.
C294 633.3
Enterococcus faecalis GdpP Is a Novel Protein
with a Potential Role in Stress Signaling and Response through
the Essential Second Messenger Cyclic Di-AMP. X. Wang, M.
Davlieva, Y. Shamoo. Rice Univ.
C295 633.4
Src Family Kinases as Proteasome Regulators
and Therapeutic Targets for Treatment of Diffuse Large B-Cell
Lymphoma. M. Cann, M. Priestman, Q. Wang, D. Lawrence.
Univ. of North Carolina at Chapel Hill.
C296 633.5
mTORC2 Regulation of the Hexosamine
Biosynthetic Pathway in Response to Nutrients. N.M. VegaCotto, J. Moloughney, P. Kim, C-C. Wu, T. Lynch, S. Zhang, M.
Adlam, S. Guntaka, P-C. Chou, J.D. Rabinowitz, G. Werlen,
E. Jacinto. Rutgers Univ., Piscataway and Princeton Univ.
C297 633.6
Designing Allosteric Switches of Kinases. N.V.
Dokholyan, O. Dagliyan, K. Hahn. Univ. of North Carolina at
Chapel Hill.
C298 633.7
Phosphorylation of Secreted Proteins by a
New Family of Kinases. V.S. Tagliabracci, S. Wiley, J. Dixon.
Univ. of Texas Southwestern and UCSD.
186
C299 633.8
Evidence for a Functional Domain in the
Extreme Carboxy Terminus of Interleukin-1 Receptor
Associated Kinase 4 S. Yeyeodu, K.S. Kimbro. North Carolina
Central Univ.
C300 633.9
Pentoxifylline Modulates the AKT/mTOR/
AMPK Pathway: Potential Role as an Adjunct in Cancer
Chemotherapy. G.T. Le, R. Canatsey, K. Tran, T.J. Monks, S.
Lau. Univ. of Arizona.
634.BIOENERGETICS
Poster
Exhibit Halls A-D
C301 634.1
Experimental Demonstration of Localized
Excess Protons at a Water-Membrane Interface and the Effect
of Other Cations on Their Stability. H.A. Saeed, J.W. Lee. Old
Dominion Univ.
635. CYTOCHROME P450
Poster
Exhibit Halls A-D
C302 635.1
Activity and Kinetic Characterization of Four
Human CYP2D6 Polymorphisms Using the Substrates
Bufuralol and Dextromethorphan. S. Glass, L.L. Furge.
Kalamazoo Col., MI.
C303 635.2
Role of SQSTM1/p62 in Cytochrome P450
Autophagy? Y. Liu, M.A. Correia. UCSF.
C304 635.3
Susceptibility of Four Human CYP2D6 Variants
and One Active Site Mutant to Inhibition by the MechanismBased Inactivator SCH 66712 V.M. Osorio, L. Lowe Furge.
Kalamazoo Col., MI
636.FLAVOPROTEINS
Poster
Exhibit Halls A-D
C305 636.1
Rate-Contributing Proton Transfers and Crystal
Structures of the Flavoenzyme Nitroreductase. A-F. Miller, W.
Pitsawong, C. Haynes, R. Koder; Jr., D. Rodgers. Univ. of
Kentucky, Brandeis Univ., Booz Allen Hamilton, Washington,
DC and City Col. New York.
C306 636.2
Examining the Functional Roles of Active Site
Residues in the Catalytic Mechanism of Dibenzothiophene
Monooxygenase. L. Gonzalez-Osorio, K. Luong, B.
Palfey, J.L. Vey. California State Univ., Northridge and Univ.
of Michigan.
SUNDAYBIOCHEMISTRY
637. OXIDATIVE PHOSPHORYLATION
640. CENTROMERES AND KINETOCHORES
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C307 637.1
Resveratrol Impairs Mitochondrial Respiration
of Saccharomyces cerevisiae L.A. Madrigal Pérez, C.
Martinez-Ortiz, A. Carrillo-Garmendia, J.M. ZamudioBolaños, G.M. Nava, R. Reynoso-Camacho, J.C. GonzalezHernandez, M. Ramos-Gomez. Inst. Tecnol. Superior de
Ciudad Hidalgo, Univ. Autónoma de Querétaro and Inst.
Tecnol. de Morelia, Mexico.
C308 637.2
Novel Roles for Uncoupling Proteins in Brown
Adipose Tissue Mitochondrial Respiratory Chain Function and
Supermolecular Organization. C.L. Riley, S. Kohno, E. Mills.
Univ. of Texas at Austin.
638. CELL CYCLE AND GROWTH CONTROL
Poster
Exhibit Halls A-D
C309 638.1
Tetrandrine Induces Cell Cycle Arrest at G0/
G1 Boundary and Cell Death In Vitro Pancreatic Cancer
Cells. K. Singh, Q. Dong, S. Koul, H.K. Koul. LSU Hlth. Sci.
Ctr., Shreveport.
C310 638.2
Regulation of AMP-Activated Protein Kinase
by Cyclin-Dependent Kinase 1 in Mitosis. S.D. Stauffer, X.
Chen, Y. Chen, J. Dong. Univ. of Nebraska Med. Ctr.
C311 638.3
Sca-1+PDGFRα- Endothilial Cell Population
Maintains the Ability of Mouse Mesenchymal Stem Cells In
Vitro. Y. Ogata, Y. Mabuchi, Y. Horiike, M. Yoshida, E.G. Suto,
N. Suzuki, C. Akazawa. Tokyo Med. and Dent. Univ.
C312 638.4
Towards
Understanding
Cell
Cycle
Regulation in the Pathogenic Cryptococcus neoformans and
Saccharomyces cerevisiae S. Kawamoto, E. Virtudazo, M.
Ohkusu, A. Suganami, Y. Tamura.
Med. Mycol. Res. Ctr. and Grad. Sch. of Med., Chiba Univ., Japan.
C313 638.5
B-Raf Is Required for Normal Cardiomyocyte
Growth. K. Rees, N. Chattergoon. Linfield Col, OR. and
Oregon Hlth. & Sci. Univ.
639. CYCLINS AND CYCLIN-DEPENDENT KINASES
Poster
Exhibit Halls A-D
C314 639.1
Tellimagrandin I Decreases Cyclin B1 Protein
Levels through SP1 in MDA-MB-231 Cells. B. White, T. Luis, A.
Rodriguez y Baena, L. Wang, S. Shah. San Jose State Univ.
C315 640.1
The Histone Tail of CPAR-1, a CENP-A Related
Protein, Is Cleaved by Separase at the Meiosis I MetaphaseAnaphase Transition in C. elegans J. Monen, N. Hattersley, A.
Desai. Ramapo Col. of New Jersey amd UCSD.
641. CHROMOSOME SEGREGATION
AND ANEUPLOIDY
Poster
Exhibit Halls A-D
C316 641.1
Iinvestigating the Mechanism of Wnt-Induced
Chromosomal Instability. A. Stiers, K. Willert. Cal Poly San
Luis Obispo, UCSD and Sanford Consortium for Regen. Med.
642. MITOTIC SPINDLE
Poster
Exhibit Halls A-D
C317 642.1
Proteomic Analysis of the Mammalian Katanin
Family of Microtubule-Severing Enzymes Defines KATNBL1 as
a Regulator of Mammalian Katanin Microtubule-Severing. K.C.
Cheung, J.Z. Torres. UCLA.
643. SPINDLE CHECKPOINT
Poster
Exhibit Halls A-D
C318 643.1
Regulation of HORMA Domain Proteins by the
Conserved Remodeler Pch2/TRI. P13 K.D. Corbett, Q. Ye, S.C.
Rosenberg, T.Y. Su. UCSD and Ludwig Inst. for Cancer Res.
644. SIGNAL TRANSDUCTION
Poster
Exhibit Halls A-D
C319 644.1
Electrostatics
and
N-Glycan-Mediated
Membrane Tethering of SCUBE1 Is Critical for Promoting Bone
Morphogenetic Protein Signaling. W-J. Liao. Inst. of Biomed.
Sci., Acad. Sinica, Taipei.
187
S
U
N
BIOCHEMISTRYSUNDAY
C320 644.2
Rab5-Activating Protein 6 Activity in
Adipogenesis. P. Chantarasinlapin, M-L. Veisaga, F.G.
Huffman, M.A. Barbieri. Florida Intl. Univ.
C321 644.3
Janus Kinase 3 Increases Phosphorylation
of Signal Transducers and Activators of Transcription 3 in
Reproductive Cells. K. Ndiaye, A. Castonguay, G. Benoit, D.W.
Silversides, J.G. Lussier. Univ. of Montreal, Saint-Hyacinthe.
C323 644.5
Identification of Cell Signaling Pathways
Involved in the Repression of Mouse ES Neuronal Differentiation
by RAR Beta. S. Joseph, D. Moses, E. Martinez-Ceballos.
Southern Univ., Baton Rouge.
C324 644.6
Extracellular
Adenosine-Induced
Rac1
Activation in Pulmonary Endothelium: Molecular Mechanisms
and Barrier-Protective Role. A. Kasa, K.M. Kim, M. Shaw, R.
Batori, S. Kumar, S.M. Black, D.J. Fulon, A. Verin. Georiga
Regents Univ. and Univ. of Arizona.
C325 644.7
Activation of Membrane Estrogen Receptor:
MAPK Signaling by Cadmium Chloride and Sodium Arsenite in
Human Lung Adenocarcinoma Cells. J.M. Hyzer, K.A. Krauss,
A.T. Black, S.L. Todd, J.T. Elpers, J.E. Hoerter, C.M. Klinge,
M.O. Huff. Bellarmine Univ. and Univ. of Louisville Sch. of Med.
C326 644.8
The Role of Molecular Chaperonin CCT and Its
Co-chaperone PhLP1 in the Assembly of mTOR Complexes.
M. Dhavale, R. Plimpton, T. Aoba, N. Tensmeyer. Brigham
Young Univ.
C327 644.9
CaM Kinase Co-localization and Regulation
of p53 in Breast Cancer Cells. C. Coblentz, R. Geck, J.M.
Schmitt II. George Fox Univ.
C328 644.10 Estrogen Receptor Alpha Utilizes TRP Channel
6 in Cancer Cell Growth. E.J. Rawlings, A.J. Rofelty, J.M.
Schmitt II. George Fox Univ.
C329 644.11 AKAP7 and Calcineurin Control CaM Kinases
and Cell Growth. L. Papenfuse, H.M. McFarland, K. DodgeKafka, J.M. Schmitt II. George Fox Univ. and UConn Hlth. Ctr.
C330 644.12 Curcumin Inhibits Development and Cell
Adhesion in Dictyostelium discoideum: Implications for YakA
Signaling and GST Enzyme Function. M. Garige, E. Walters.
Howard Univ.
C331 644.13 Peptide Ligand C391 as a Potential PAR-2
β-Arrestin Biased Antagonist. M. Ming, M.C. Yee, K.J. Lee,
M.D. Siegler, M. Arrellano, S. Aghayan, K. DeFea. Univ. of
California, Riverside.
645. ADAMS AND OTHER PROTEASES
Poster
Exhibit Halls A-D
C332 645.1
The Potential Link of COMP-ADAMTS and
Aggrecanase-ADAMTS Genes with Osteoarthrit. K. Demircan,
G. Gürlü, K.N. Güven, T. Fıstık, H. Çakırbay, B. Yanık. Turgut
Ozal Univ. and Hosp., Hacettepe Univ., Gazi Univ., and Med.
Park Hosps., Ankara, Turkey.
188
646.AGING
Poster
Exhibit Halls A-D
C333 646.1
The Putative Role of Lin28 in Aging of
Aeolosoma viride Y.Y. Chen. Natl. Taiwan Univ.
C334 646.2
Transcriptional
Changes
in
Aging
Photoreceptor Cells of Drosophila melanogaster K.J. Brennan,
H. Hall, V.M. Weake. Purdue Univ.
647. APOPTOSIS AND CELL STRESS
Poster
Exhibit Halls A-D
C335 647.1
FAM83G Is a Novel Apoptosis Inducer. S.
Okada, M. Yamada. Gunma Univ., Japan.
C336 647.2
Effect of Pathway-Interconnectors in SEBInduced Apoptosis Related Events in Human PBMCs. E.
Geddes, M. Hendricks, C. Doyle, D. Borgos, D. Burton, C.
Mendis. Univ. of Wisconsin-Platteville.
C337 647.3
Role of Endogenous Antioxidant Peroxidases
in Cancer Cell Apoptosis Induced by TNF-A. S. Lee. Ewha
Womans Univ., South Korea.
C338 647.4
Caspase Activity in Early Stage Regeneration
of A. viride Regulated by the Wnt/β-Catenin Signaling Pathway.
S. Fok. Natl. Taiwan Univ.
C339 647.5
Examining Apoptosis in a Sepsis Cell Culture
Model. B. Davis, V. Del Gaizo Moore. Elon Univ.
C340 647.6
Myocardin Regulated Genetic Pathway
Modulates Mitochondrial Permeability Transition Pore Closure
to Prevent Cell Death during Cardiac Differentiation. W. Mughal,
S. da Silva Rosa, D. Chapman, Y. Hai, W. Diehl-Jones, J.
Gordon. Univ. of Manitoba and Athabasca Univ., Winnipeg.
C341 647.7
Isolated Extracellular Domain of DR5 Is a
Potential Inhibitor of Apoptosis. N. Vunnam, J.N. Sachs. Univ.
of Minnesota, Minneapolis.
C342 647.8
Expression and Functional Analysis of Fas
Ligand-Like Protein from Silkworm, Bombyx mori K. Yanagida,
T. Yabu, H. Shiba. Col. of Bioresource Sci., Nihon Univ., Japan.
C343 647.9
CREB Regulates the Expression of PERK
and IRE1a, and Controls Unfolded Protein Response under
Hypoxic Conditions. K. Nakayama. Tokyo Med. and Dent. Univ.
C344 647.10 Regulation of Protein Kinase R Activation
during Cell Stress by TRBP Phosphorylation. E.E. Chukwurah,
R.C. Patel. Univ. of South Carolina.
C345 647.11 Protective Roles of Sep15 against Cataract
Formation. N. Yin, K. Huang. Huazhong Univ. of Sci. and
Technol., China.
SUNDAYBIOCHEMISTRY
648. BIOCHEMICAL PHARMACOLOGY
651. CYTOKINE AND GROWTH FACTOR SIGNALING
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C346 648.1
Evaluating Tim12p as a Potential Target of
the Anti-cancer Compound Parthenolide. E.K. Babb, K.P.
Callahan. St. John Fisher Col., NY.
C347 648.2
Modulation of PON2 and Proinflammatory
Cytokine Genes in Rat Tissue Exposed to Combined Oral
Contraceptive Ethinylestradiol and Levonorgestrel. A.D. Wusu,
S.O. Rotimi, G.M. Saibu, O.A. Rotimi, R.A. Giwa. Lagos State
Univ. and Covenant Univ., Nigeria.
C348 648.3
Yeast Strains Heterozygous for YTA12 Are
Sensitive to the Anti-cancer Compound Parthenolide. R.E.
Hojnacki, K.P. Callahan. St. John Fisher Col., NY.
649.CASPASES
Poster
Exhibit Halls A-D
C349 649.1
Fine Tuning the Catalytic Activity of Caspase-3
by Phosphorylation and Site-Directed Mutagenesis of an
Allosteric Site. M.E. Thomas III, C. Clark. North Carolina State
Univ. and Univ. of Texas at Austin.
C350 649.2
Phage Display and Structural Studies Reveal
Plasticity in Substrate Specificity and Allosteric Regulation
of Caspase-3 from Zebrafish. C. Clark, M.B. Tucker, S.H.
MacKenzie, J.J. Maciag, H.B. Dirscherl, P.B. Swartz, J.B.
Yoder, P.B. Hamilton. Univ. of Texas at Arlington and North
Carolina State Univ.
C351 649.3
A Tunable Allosteric Library of Caspase-3
Identifies Coupling between Conserved Water Molecules and
Conformational Selection. J.J. Maciag, S.H. Mackenzie, M.
Tucker, J.L. Schipper, P. Swartz, A.C. Clark. Univ. of Texas at
Arlington, North Carolina State Univ. and Duke Univ.
650. CELL PROLIFERATION
Poster
Exhibit Halls A-D
C352 650.1
Epidermal Growth Factor Substrate 8 Is an
Essential Partnering Factor of the Forkhead Box Transcription
Factor FOXM1 in the Regulation of Cell Proliferation in Cervical
Cancer Cells. W.L. Ngan, K-M. Yao, W.Y. Leung, D.W. Chan.
The Univ. of Hong Kong.
C353 650.2
Effect of Covalent TAK1 Inhibitors on the
Viability of Pancreatic, Renal and Colon Cancer Cells. F.
Bernard, W.D. Singer, D. Gurbani, T. Li, S.M. Lim, N. Gray, K.
Westover. Univ. of Puerto Rico, Univ. of Texas Southwestern
Med. Ctr. and Dana Farber Cancer Inst.
C354 651.1
Role of ERK1/2 and p38 MAPKs in TributyltinStimulated Interleukin 1 Beta Secretion and Production from
Human Immune Cells. M. Boules, S. Brown, M. Whalen.
Tennessee State Univ.
C355 651.2
Effects of Pentachlorophenol on Secretion of
Interferon Gamma from Human Immune Cells. R. Massawe,
M. Whalen. Tennessee State Univ.
C356 651.3
Pentachlorophenol
and
Dichlorodiphenyltrichloroethane Alter Secretion of Interleukin
1 Beta from Human Immune Cells. T.J. Martin, M. Whalen.
C357 651.4
Tributyltin Alters Secretion of Interleukin 6 from
Human Immune Cells. W.J. Wilburn, S. Brown, M. Whalen.
C358 651.5
Dibutyltin Exposures Alter Secretion of
Interleukin 6 from Human Immune Cells. S. Brown, W. Wilburn,
M. Whalen. Tennessee State Univ.
C359 651.6
Reactive Oxygen Species-Dependent PKB
Activation Contributes to Insulin-Like Growth Factor 1-Induced
Phosphorylation of Histone Deacetylase 5 in Vascular Smooth
Muscle Cells. P. Pietruczuk, A.K. Srivastava. CRCHUM, Univ.
of Montreal.
C360 651.7
Ex Vivo Quantification of Transforming Growth
Factor-Beta1 in Equine Laminitis. L.D. Gutzmann, P.J.
Johnson, R.R. Mohan. Univ. of Missouri-Columbia and Harry
S. Truman VA Hosp.
652. POSTTRANSLATIONAL MODIFICATIONS (CELL
SIGNALING, KINASE AND CHEMOTHERAPY)
Poster
Exhibit Halls A-D
C361 652.1
Polyisoprenylated Cysteinyl Amide Inhibitors
Block Innate and VEGF-Induced Angiogenesis. A.T. Nkembo,
E. Ntantie, R.A. Poku, O. Salako, F. Amissah, N.S. Lamango.
Florida A&M Univ.
C362 652.2
O-GlcNAc Regulates p53 in Ovarian Cancer.
R.M. Queiroz, J. Chien, R. Madan, C. Slawson, W. Dias. Fed.
Univ. of Rio de Janeiro and Univ. of Kansas Med. Ctr.
C363 652.3
Combination of Aurora A and Haspin Inhibitors
Enhances p53 Expression and Tumor Growth Inhibition in
Human Colorectal Cancer. Y-H. Chang, C-I. Lin, Z-C. Chen,
K-K. Liu, J-I. Chao. Natl. Chiao Tung Univ., Taiwan.
C364 652.4
Site Specific Oxidation of Calmodulin by
Methionine Sulfoxide Reductase A in Drosophila S. Tarafdar,
N.M. Rusan, R.L. Levine. NHLBI, NIH.
C365 652.5
G-Protein Gamma Subunits as Novel
Regulators of G-Protein Signaling. S. Choudhury, M. Torres.
Sch. of Biol., Georgia Tech.
C366 652.6
O-GlcNAc
Regulates
CD4+
T
Cell
Differentiation. M. Machacek, C. Slawson, P. Fields. Univ. of
Kansas Med. Ctr.
189
S
U
N
BIOCHEMISTRYSUNDAY
C367 652.7
A Novel Compound PT-262 Inhibits Oct4 and
Nanog on the Survivin Blockage and Apoptosis Induction
in Human Lung Cancer. Y-T. Chen, J-Y. Li, P-Y. Pan, C-P.
Chen, J-I. Chao. Natl. Chiao Tung Univ. and Natl. Don Hwa
Univ., Taiwan.
C368 652.8
Regulation of the Unfolded Protein Response
by Fic-Mediated Adenylylation/AMPylation. S. Mattoo, A.
Sanyal. Purdue Univ.
C369 652.9
Structural Analysis of PTM Hotspots Reveals
Large Body of Putative Regulatory Elements with Predicted
Biological Function in Eukaryotic Protein Families. M. Torres,
H. Dewhurst, S. Choudhury. Georgia Tech.
653. LIPIDS AND INFLAMMATION
Poster
Exhibit Halls A-D
C370 653.1
Leukotriene B4 Receptor Type 2 Enhances
Skin Barrier Function by Regulating Tight Junction Proteins. Y.
Ishii, K. Saeki, T. Yokomizo. Kyushu Univ. and Juntendo Univ.
Sch. of Med., Japan.
C371 653.2
Chlorinated Lipids Are Potential Mediators of
Microcirculatory Dysfunction during Sepsis. D.A. Ford, R.J.
Korthuis, R.S. Hotchkiss, C.J. Albert, J. McHowat. Saint
Louis Univ., Univ. of Missouri-Columbia and Washington Univ.
C372 653.3
Production of Novel Glutathione Adducts of
Halogenated Fatty Aldehydes in Inflammatory Animal Models.
M.A. Duerr, R. Aurora, R.J. Korthuis, D.A. Ford. Saint Louis
Univ. and Univ. of Missouri-Columbia.
C373 653.4
Chlorinated Lipids Activate Human Neutrophils.
E.N.D. Palladino, D.A. Ford. Saint Louis Univ.
C374 653.5
Characterization
of
2-Chlorofatty
Acid
Signaling Pathways. C. Hartman, T.Y. Cho, J. McHowat, D.A.
Ford. Saint Louis Univ.
C375 653.6
BLT2 Receptor Protects against Lethal Acute
Lung Injury Induced by a Pneumococcal Toxin Pneumolysin.
M. Shigematsu, T. Koga, K. Saeki, T. Okuno, T. Yokomizo.
Juntendo Univ. and Kyushu Univ., Japan.
C376 653.7
Lysophospholipid Receptors, as Novel Danger
Associated Molecular Pattern Receptors and Homeostasis
Associated
Molecular
Pattern
Receptors
Modulate
Inflammation – Novel Paradigm and Therapeutic Potential. X.
Wang, Y-F. Li, H. Fu, C. Johnson, Y. Shao, R. Cueto, H. Wang,
X-F. Yang. Temple Univ. Sch. of Med.
C377 653.8
Bisphenol A Induces Gene Expression Related
to Inflammation and Lipid Accumulation in Adipocytes. H.W.
Lee, J. Kim. Sungkyunkwan Univ., South Korea.
C378 653.9
N-Docosahexaenoylethanolamine Ameliorates
LPS-Induced Brain Inflammation through Suppression of
Neutrophil/Macrophage as Well as Microglia Activation. T.
Park, J. Lee, H. Chen, H-Y. Kim. NIAAA, NIH, Rockville, MD.
C379 653.10 Alcohol and HIV Protease Inhibitor-Induced
Inflammasome Activation and Liver Lipotoxicity. M. Hinton.
Virginia Commonwealth Univ.
C380 653.11 Effects of Gryllus bimaculatus (Gb) Fractions
on Alcoholic Hepatitis. M.Y. Ahn, J.S. Hwang, .Y. Yun. Natl.
Acad. of Agr. Sci., Wanju, South Korea.
190
654. LIPIDS AND CONTROL OF GENE EXPRESSION
Poster
Exhibit Halls A-D
C381 654.1
Microarray Analysis and Anti-hyperglycemia
Effect of Gryllus bimaculatus (Gb, a Type of Cricket) Extract in
Rats on High Fat Diet. M.Y. Ahn, J.S. Hwang, E.Y. Yun. Natl.
Acad. of Agr. Sci., Wanju, South Korea.
C382 654.2
Transcriptome Analysis of Illinois Abdominal
and Cardiac Adipose. W. Treible, J.W. Finger; Jr., T. Tuberville,
T.C. Glenn, M. Hamilton, S.J. Lamont, C.J. Schmidt, B.K.
Schneider, C. Kern, A. Hubbard. Univ. of Delaware, Univ. of
California, Davis, Univ. of Georgia and Iowa State Univ.
655. LIPIDS AND LIPID SIGNALING
Poster
Exhibit Halls A-D
C383 655.1
FTY720 Induces Necroptosis by Regulating
Ceramide Signaling at the Plasma Membrane. R. Ndeto, B.
Ogretmen. Med. Univ. of South Carolina.
C384 655.2
Brain
Stearoyl-CoA
Desaturase-1
Deficiency Protects against High-Fat Diet-Induced Metabolic
Derangements. A.C. Zdechlik, K.R. Harrington, Maggie
S. Burhans, Chang-An Guo, L. Bond, J. Ntambi. Univ.
C385 655.3
Hepatic Stearoyl-CoA Desaturase Deficiency
Suppresses Gluconeogenesis by Regulating Lipid Profile of
Mitochondria. C. Guo, J.M. Ntambi. Univ. of Wisconsin-Madison.
656. LIPID SECOND MESSENGERS
Poster
Exhibit Halls A-D
C386 656.1
Diacylglycerol
Kinase
ζ
Produces
16:0-Containing Phosphatidic Acid Molecular Species during
Neuroblastoma Cell Differentiation. S. Mizuno, F. Sakane.
Chiba Univ., Japan.
657. LIPID STORAGE
Poster
Exhibit Halls A-D
C387 657.1
Sub-chronic Exposure to Cadmium at Low
Levels Alters Microsomal Lipid Storage in Rat. O.O. Ogunrinola,
D.A. Wusu, K. Afolabi, E. Balogun, O. Ademuyiwa, O.
Odukoya. Lagos State Univ., Ladoke Akintola Univ., Univ. of
Ilorin and Fed. Univ. of Agr. Abeokuta, Nigeria.
SUNDAYBIOCHEMISTRY
C388 657.2
Choline Deficiency Alters Lipid Droplet
Composition and Size. E. Brown, E. Townsend, A. Hains, L.
Listenberger. St. Olaf Col., MN.
658. LIPID TRAFFICKING
Poster
Exhibit Halls A-D
C389 658.1
Trafficking of Acetyl-C16-Ceramide-NBD with
Long-Term Stability and No Cytotoxicity into the Golgi Complex.
H. Nakamura, T. Makiyama, N. Nagasaka, H. Yamashita, T.
Honda, N. Yamaguchi, A. Nishida, T. Murayama. Grad. Sch.
of Pharmaceut. Sci., Chiba Univ.
C390 658.2
The Unique Relationship between Niemann
Pick Type C2 Protein and Lysobisphosphatidic Acid. A.
Jochum, R. Li, S. Newton, L. McCauliff, J. Storch. Rutgers
Univ. and Ctr. for Lipid Res.
C391 658.3
Screening for Genes Required for Coenzyme
Q Uptake and Trafficking in S. cerevisiae C. Kampmeyer, A.M.
James, M.P. Murphy, C.F. Clarke. UCLA and Wellcome Trust,
Cambridge, U.K.
659.LIPIDOMICS
Poster
Exhibit Halls A-D
C392 659.1
PGC-1α-Mediated Changes in Phospholipid
Profiles of Exercise-Trained Skeletal Muscle. S. Miura, N.
Senoo, N. Miyoshi, N. Goto-Inoue, K. Minami, R. Yoshimura,
A. Morita, N. Sawada, J. Matsuda, Y. Ogawa, M. Setou, Y.
Kamei. Univ. of Shizuoka, Nihon Univ., Kyoto Prefect. Univ.,
Univ. of Chicago, Tokyo Med. and Dent. Univ., Natl. Insts. of
Biomed. Innovation, Hlth. and Nutr., Ibaraki and Hamamatsu
Univ. Sch. of Med., Japan.
C393 659.2
FOXO1-Induced
Atrophy
Changes
in
Phospholipid Profiles of Skeletal Muscle. N. Senoo, N.
Miyoshi, E. Kobayashi, A. Morita, Y. Kamei, S. Miura. Univ. of
Shizuoka and Kyoto Prefect. Univ.
660. MEMBRANE CONTACT SITES AND
LIPID TRAFFICKING
Poster
C396 660.3
The Lipid Transfer Protein STARD3 Modulates
Intracellular Cholesterol Localization. C.L. Tomasetto, L.
Wilhelm, G. Drin, F. Alpy. IGBMC, Illkirch and IPCM, Valbonne.
C397 660.4
Molecular Determinants of the Localization of
the Phosphatidylinositol/Phosphatidic Acid Transfer Protein,
Nir2 to ER-PM Contact Sites. Y.J. Kim, M.L. GuzmanHernandez, E. Wisniewski, N. Echeverria, T. Balla.
NICHD, NIH.
661. PROTEIN-LIPID INTERACTIONS
Poster
Exhibit Halls A-D
C398 661.1
Substrate Selectivity of Lysophospholipid
Transporter LplT Involved in Membrane Phospholipid
Remodeling in Escherichia coli Y. Lin, M. Bogdanov, S. Tong,
Z. Guan, L. Zheng. Univ. of Texas Hlth. Sci. Ctr. at Houston
Med. Sch.
C399 661.2
Investigation
of
Molecular
Interactions
between Lysophospholipase A2 and Its Diverse Bioactive Lipid
Substrates. J.A. Wepy, S. Xu, S.N. Kudalkar, L.J. Marnett.
Vanderbilt Univ.
C400 661.3
HspA1A, a Seventy-kDa Heat Shock Protein,
Binds to Phosphoinositides. B. Kdeiss, C. McCallister, N.
Nikolaidis. California State Univ. Fullerton.
C401 661.4
Acrolein Modification of Apolipoprotein A-I
Alters Protein Stability and Antimicrobial Activity. H.J. Hong, P.
Weers. California State Univ. Long Beach.
C402 661.5
Binding of Lysine Residues of Apolipophorin III
to Phosphatidylglycerol Membranes. K. Shah, P.M.M. Weers.
C403 661.6
PIP2 Mediated Influence on Serotonin
Transport Function. T. Hofmaier, A. Anderluh, O. Kudlacek,
T. Stockner, G. Schütz, H. Sitte. Med. Univ. of Vienna, Austria
and Tech Univ. of Vienna.
C404 661.7
Studies Into the Synthetic Analogs of Key
Intermediates, and Ring Precursors in the Biosynthetic
Pathway of Coenzyme Q: Synthesis and Metabolism. A.
Nag, C. He, J.N. Shepherd, L. Fernandez, C.F. Clarke, J.M.
Villalba. UCLA, Gonzaga Univ. and Univ. of Cordoba, Spain.
C405 661.8
Saccharomyces cerevisiae Coq10, a Putative
START Domain Protein Binds CoQ and Late-Stage CoQ
Biosynthetic Intermediates. H.S. Tsui, C.F. Clarke. UCLA.
662. ADVANCING TEACHING AND LEARNING
IN THE BIOCHEMISTRY/MOLECULAR
BIOLOGY CLASSROOM
Exhibit Halls A-D
Poster
Exhibit Halls A-D
C394 660.1
An EE-Golgi Tether Facilitates Ceramide
Transfer Out of the ER and Alleviates Ceramide Toxicity. L-K.
Liu, A. Toulmay, W. Prinz. NIDDK, NIH.
C395 660.2
Phosphatidylserine Production at Membrane
Contacts Sites Enhances Its Transport Out of the Endoplasmic
Reticulum M. Kannan, S. Lahiri, L-K. Liu, W.A. Prinz. NIDDK,
NIH and Univ. of Virginia.
C406 662.1
Research for All: Large Introductory Laboratory
Classes Investigate the Evolutionary Conservation of Metabolic
Pathways. C.M. O’Connor, D.M. Warner. Boston Col.
C407 662.2
Using Pop-It Beads in the Classroom to
Enhance Student Comprehension of Enzyme Catalysis and
Reaction Rate. A. Gehret. Rochester Inst. of Technol.
191
S
U
N
BIOCHEMISTRYSUNDAY
C408 662.3
The Biotech Explorers Pathway: Teams Taking
First Steps toward Scientific Challenges. B.G. Cascella, J.M.
Jez. Washington Univ. in St. Louis.
C409 662.4
Writing
throughout
the
Biochemistry
Curriculum: Synergistic Inquiry-Based Writing Projects for
Biochemistry Students. P. Mertz, C. Streu. St. Mary’s Col. of
Maryland and Albion Col., MI.
C410 662.5
Integrating Rare Disease Research into an
Undergraduate Liberal Arts Curriculum to Enhance the Pace
of Rare Disease Gene Discovery for Underserved Populations
and Promote Stem Retention. R.N. Jinks, B.K. Davis, D.M.
Roberts, E. Rice, K.W. Brigatti, E.G. Puffenberger, K.A.
Strauss. Franklin & Marshall Col. and Clin. for Spec. Children,
Strasburg, PA.
C411 662.6
Developing Science Leaders through Applied
Learning Experiences. J.M. Richardson. Austin Col.
C412 662.7
Teaching Matters: Undergraduate Grant
Writing Curriculum. K.R. Miller. Univ. of Mount Union, OH.
C413 662.8
A Flipped Classroom Format Enhances
Learning of Molecular Biology in an Introductory, Biology Major
Course at a Small Liberal Arts University. C.L. Clauson, A.C.
Shor. Saint Leo Univ.,FL.
C414 662.9
Increasing Integration and Retention of
Metabolic Pathways by Undergraduate Biochemistry Majors
through Creation of a Concept Map. V. Del Gaizo Moore.
Elon Univ.
C415 662.10 Fostering Remembering: Strategies for
Helping Students Link Prerequisite Knowledge to Learning
Biochemistry. A.T.S. Taylor, W.R.P. Novak. Wabash Col., IN.
C416 662.11 Exploring the Impact of Jargon on Student
Learning in Biology: Student Understanding, and SelfPerception of Understanding, of Technical Vocabulary. L.
McDonnell. Univ. of British Columbia and UCSD, J. Zukswert,
M. Barker.
C417 662.12 Integration of Biochemistry and Problem
Solving-Based Pedagogy throughout the Chemistry Curriculum
in Support of Learning Outcomes Articulated by the Association.
of American Medical Colleges., the ASBMB and the American
Chem. Soc. H.V. Jakubowski, K. Graham, E. McIntee, C.
Schaller. Col. St. Benedict/St. John’s Univ., MN.
C418 662.13 Specifications
Based
Grading:
Nearly
Pointless Education That Points Students to Key Concepts.
R.P. Rylaarsdam, C. Heinz. Benedictine Univ.
C419 662.14 A Two-Dimensional and Non-hierarchical
Framework of Bloom’s Taxonomy for Biology. S.M. Lo, V.M.
Larsen, A.T. Yee. UCSD and Northwestern Univ.
C420 662.15 Integration of Undergraduate Research into
the Biomolecular Science Curriculum Using Thematically
Linked Laboratory Courses in Biochemistry, Chemical Biology,
and Neurobiology. R.J. Johnson, G. Hoops, J. Kowalski.
Butler Univ.
C421 662.16 FauxSeqEvolver Software Automates the
Electronic Creation of Novel Pseudo Biological Sequences,
Generating Truly Novel “Unknown” Sequences for Use in
Bioinformatic Education. R. Rutherford. Seattle Univ.
C422 662.17 Is More Activity Always Better? A DepartmentWide Study of Relationships between Classroom Practices
and Student Performance. M.K. Barker, L. Weir, L. McDonnell,
N. Schimpf, T. Rodela, P. Schulte. Univ. of British Columbia,
Kwantlen Polytech Univ., Canada and UCSD.
C423 662.18 Breast Cancer in the Age of Personalized
Medicine: A CURE Design for Aspiring Physicians. P.A.G.
Soneral. Bethel Univ.
192
C424 662.19 Lowering the Activation Barrier, Not the
Academic Bar: The Role of Contract Grading in Decreasing
DFW Rates in Introductory Biochemistry. E.G. Offerdahl, A.
Hodgson, C. Krupke. North Dakota State Univ.
C425 662.20 In Silico Phage-Hunting in Sinorhizobium
Genomes: Incorporating Original Research in Undergraduate
Molecular Biology and Microbiology Courses. B. Martinez-Vaz,
A. Jensen, M. Vang. Hamline Univ.
663. INTEGRATING COMPLEMENTARY SKILLS INTO
GRADUATE AND POSTDOC TRAINING
Poster
Exhibit Halls A-D
C426 663.1
Innovative Program That Broadens Career
Development Training through Community Partnerships and
Outreach. T.M. Evans. Grad. Sch. of Biomed., Sci., Univ. of
Texas Hlth. Sci. Ctr. at San Antonio.
C427 663.2Withdrawn
C428 663.3
Changing Career Prospects Are Changing the
Needs in Graduate and Post-Doc Training. S.E. Feeney. Univ.
of California, Davis.
664. LEARNING TOOLS IN MOLECULAR
BIOLOGY AND BIOCHEMISTRY
UNDERGRADUATE EDUCATION
Poster
Exhibit Halls A-D
C429 664.1
Research as a Tool for Undergraduate
Education Using Drosophila melanogaster R.P. Rogers.
Wentworth Inst. of Technol., Boston.
C430 664.2
A Collaboration between the ASBMB and
Course Source to Promote the Use of Active Learning
Strategies in BMB Courses. K.M. Fox, N. Grover. Union Col.,
NY and Colorado Col.
C431 664.3
Using Readings and Discussion to Teach
Ethics in the Undergraduate Science Curriculum. J.T. Tansey.
Otterbein Univ.
665. UNDERGRADUATE RESEARCH
Poster
Exhibit Halls A-D
C432 665.1
Effects of Simulated Microgravity on the
Microbial Physiology of Ralstonia pickettii Isolates from the
International Space Station. S.J. Fergione. Missouri Western
State Univ.
C433 665.2
Undergraduate Students Engagement in Basic
Biochemistry Course Activities in Sudan and Saudi Arabia.
M.E.A. Mohammed. King Khalid Univ., Saudi Arabia.
SUNDAYBIOCHEMISTRY
C434 665.3
Do the TWIST: Transcription and Regulation of
Estrogen Receptor Operon. A. Krishnaswamy, C. Eshleman,
A. Fortier, M. Kahn, A. Kepner, A. Naderi, S. Om, A. Baxley,
T. Link, S. Nowak. Walton H.S., Marietta, GA and Kennesaw
State Univ.
C435 665.4
Characterization of Rare Oncogenic Mutations
in the Kinase Domain of Epidermal Growth Factor Receptor. Z.
Ruan, S. Katiyar, N. Kannan. Univ. of Georgia.
C436 665.5
Screening Unnatural Fluorescent Amino Acids
for Incorporation Into E. coli Cellular Machinery. C. Mammoser,
S. Dhar, B. Kelly, L. Rowe. Valparaiso Univ.
C437 665.6
Oligomerization of Wild-Type Fumarase and
a Mutant Associated with Fumarate Hydratase Deficiency. A.
Bulku, N. Aleksanyan, M. Berkmen. Suffolk Univ., MA.
C438 665.7
Problematic 15-PGDH: The Link between 15PGDH and Uncontrolled Tissue Growth. D. Chyong, A. Alluri,
T. Arpornsuksant, M. Hu, S. Jain, M. Williams, A. Baxley, T.
Link, H-K. Na. Walton H.S., Marietta, GA and Col. of Human
Ecol., Sunshine Women’s Univ., Seoul.
C439 665.8
A Phenylalanine Fiasco: The Structure of
Phenylalanine Hydroxylase and Its Impact on Phenylketonuria.
J. Kahn, A. Koh, R. Luckcuck, J. McNeice, E. Walter, W. Yao,
A. Baxley, T. Link. Walton H.S., Marietta, GA.
C440 665.9
Design Elements of a High Enrollment CourseBased Undergraduate Research Experience May Lead to
Inaccurate Student Conceptions about Scientific Research.
K.M. Cooper, C. Wassef, S.E. Brownell. Arizona State Univ.
C441 665.10 Collaborative
Undergraduate
Research
Laboratory: Engaging Students in Research Using Yeast
Molecular Genetics. A.H. Munshi, T.L. Johnson. UCLA.
C442 665.11 Transformation and Assessment Mapping of
a Course Undergraduate Research Experience. K. Clase, A.
Zissimopoulos. Purdue Univ. and Univ. of Chicago.
C443 665.12 Development
of
a
Research-Intensive
Undergraduate Teaching Program in Biochemistry. R. Milner.
Univ. of Alberta.
C444 665.13 The Small World Initiative™: An Innovative
Crowdsourcing Platform for Antibiotics. A.M. Barral, H.
Makhluf, N.A. Broderick, E.L. Kurt. National Univ., Costa
Mesa and La Jolla, Univ. of Connecticut and Inst. for Life Sci.
Collaboration, New Haven.
C445 665.14 Creating Authentic Research Experiences for
Student Engagement and Success. H.A. Makhluf. National
Univ., CA.
C446 665.15 Integrating
Research
on
Student
Understanding of Protein Structure with Implementation of
a Biochemistry Laboratory Experiment: Circular Dichroism
of Globular Proteins. C. Lewis, M-T. Nguyen, F. Texter, J.L.
Schlessman, M. Teichert. U.S. Naval Acad. and Albright
Col., PA.
C447 665.16 Identfication of Microbial Symbionts Harbored
by the Chesapeake Bay Sponge, Clathria prolifera H. Kerins,
K. Rubenstein, M. Hill, J.D. Dattelbaum. Univ. of Richmond.
C448 665.17 Construction of a Maltose Biosensor Using the
Thermotoga maritima Maltose Binding Protein. L. Masson,
J.D. Dattelbaum. Univ. of Richmond.
C449 665.18 Lessons, Experiences and Opportunities
Gained through a 3-Year Undergraduate Research Study. K.
Carter, J. Mytych, S. Soriano, N. Parmar. California State
Univ. Channel Islands.
C450 665.19 Identification
of
Genetic
Sequences
Recognized by Human SC35 Protein Using Artificial Neural
Networks: A Deep Learning Approach. A.J. Luke, S. Fergione.
Missouri Western State Univ.
C451 665.20 Non-profit Patient Research Services from
Rare Genomics Institute Enable Insight Into Rare Diseases
through Genome Sequencing and Cloud Collaboration. B.
Tucker, E. Aguilar, D. Gurnon. DePauw Univ.
666. MOLECULAR VISUALIZATION
Poster
Exhibit Halls A-D
C452 666.1
Molecular Visualization in the Classroom:
Learning Goals and Competencies. D.R. Dries, P.A. Craig,
D.M. Dean, L. Listenberger, W.R.P. Novak, M.A. Franzen.
Juniata Col., PA, Rochester Inst. of Technol., Univ. of Saint
Joseph, CT, St. Olaf Col., MN, Wabash Col., IN and Milwaukee
Sch. of Engin.
C453 666.2
Combining Molecular Visualization with Bench
Methods in a Hypothesis-Driven Undergraduate Biochemistry
Lab Course. P.A. Craig, J.L. Mills, C. Daubner, M.J. Pikaart.
Sch. of Chem. & Mat. Sci., Rochester Inst. of Technol., Sch. of
Sci., Engin. and Technol., St. Mary’s Univ., San Antonio and
Hope Col., MI.
C454 666.3
Teaching Students to See Biologically Relevant
Interactions When You Can’t See Them: Protein Visualization
Instruction in the Online Classroom. D.M. Dean. Univ. of Saint
Joseph, CT.
C455 666.4
Taxonomy
of
Biochemistry
External
Representations Applied to Biochemistry Textbooks. K.
Linenberger. Kennesaw State Univ.
C456 666.5
Visual Models to Use in the Classroom for
Teaching Immunology Concepts. A. Williams. Univ. of Tampa.
C457 666.6
Reviving
“Byron’s
Bender”:
Hands-On
Molecular Visual and Tactile Learning at the Most Basic Level.
J.T. Hazzard, A. Issaian. Univ. of Arizona and Univ. of Colorado
Anschutz Med. Campus.
193
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Nutrition
667. GLOBAL NUTRITION: OBESITY, NONCOMMUNICABLE DISEASES AND THE
NUTRITION TRANSITION
Poster
(Sponsored by: Global Nutrition Council)
Exhibit Halls A-D
Presentation time: 12:45 pm–1:45 pm (I);
1:45 pm–2:45 pm (II)
D1
I667.1
Global Food System Changes Have
Created New Drivers and New Challenges for Low and Middle
Income Countries. B.M. Popkin. Univ. of North Carolina at
Chapel Hillll.
D2
II667.2 Metabolic
Changes
Underlying
Interactions between Obesity and Non-alcoholic Fatty Liver
Disease in South Asian Adults. K. Albracht-Schulte, N.
Kalupahana, L. Ramalingam, S. Rosairo, S. Wijetunge,
H.M.S.R.B. Kotakadeniya, R.M.C.J. Ratnayake, N. MoustaidMoussa. Texas Tech Univ. and Univ. of Peradeniya, Sri Lanka.
D3
I667.3
Obesity Risks Associated with Lowand High Birth Weight and They Varied by Population Obesity
Prevalence: A Systematic Review and Meta-analysis. T. Song,
Y. Wang, W. Huang, L. Lu, Y. Zhao, M. Sharma, Y. Zhang.
Chongqing Med. Univ., China, Univ. at Buffalo, SUNY and
Jackson State Univ., MA.
D4
II667.4 Anthropometric,
Blood
Pressure,
Dietary, and Physical Activity Differences in Urban- Compared
to Rural-Dwelling Women in the Chimborazo Region of
Ecuador. C. Melby, F. Orozco, D.X. Ochoa, M. Muquinche,
M. Padro, F. Munoz. Sch. of Publ. Hlth., Colorado State
Univ., Sch. of Publ. Hlth., Univ. San Francisco de Quito, ESP
de Chimborazo, Riobamba and Visor Análisis Est. Cía. Ltda,
Quito, Ecuador.
D5
I667.5
Iron Nutritional Status of Overweight
and Obese Subjects: Relation with BMI and Inflammation. L.
Zago, M. Pandolfo, C. Carbia, M. Lardo, A. Weisstaub, A.L.
Felipoff, H. Dupraz, N. Presner, C. Perdomo, M.E. Río, C.
González Infantino. Fac. of Pharm. and Biochem. and Hosp.
Clins., Univ. of Buenos Aires
D6
II667.6
Changes in Physical Activity Patterns
and Dietary Intake in Chinese Youth and Their Associations
with Obesity: A Longitudinal Study in Nanjing City, China. H.
Chang, F. Xu, H. Xue, Y. Wang. Univ at Buffalo, SUNY and
Nanjing Ctrs. for Dis. Control and Prevent.
D7
I667.7
Unhealthy Weight among Mothers and
Young Children in the Middle East and North African Region.
R. Jones, S. Cunningham. Emory Univ.
D8
II667.8
The Trend of Korean Staple Food Intake
and Prevalence of Obesity in Korean Adults: The Korean
National Health and Nutrition Examination Survey (KNHANES)
1998-2012S-A. Kim, K. Ha, J. Kim, H.Y. Paik, H. Joung. Grad.
Sch. of Publ. Hlth., Seoul Natl. Univ.
D9
I667.9
Overweight and Obesity among Women
in a Predominantly Rural District of Ghana. G.S. Marquis,
E.K. Colecraft, B. Bannerman, T. Thompson-Colón. Sch. of
Dietetics and Human Nutr., McGill Univ. and Univ. of Ghana.
194
D10 II667.10
Preliminary
Understanding
of
Hypertensive Clinics and Hypertensive Patients Attending
Hypertensive Clinics in Malawi. E.W.P. Siyame, L.S. Goodell,
J.C. Allen. North Carolina State Univ.
D11
I667.11
Dietary Comparisons between Mexican
and American College-Aged Adults. B. Hannon, K.N.
Robinson, J.M. Vargas Morales, C. Aradillas García, M.
Teran-Garcia. Univ. of Illinois, Urbana and Univ. Autonoma de
San Luis Potosi, Mexico.
668. GLOBAL NUTRITION: NUTRITION, INFECTION
AND INFLAMMATION
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D12 II668.1
α-1 Acid Glycoprotein but Not
C-Reactive Protein Is Associated with Significantly Lower
Serum Zinc Concentrations among Congolese Children Aged
6-59 Months and Has a Substantial Impact on Prevalence
Estimates of Zinc Deficiency. C.D. Karakochuk, K.C. Whitfield,
S.I. Barr, E. Boy, M. Moursi, P.L. Tugirimani, L. Houghton,
R.S. Gibson, T.J. Green. Univ. of British Columbia, IFPRI,
Washington, DC, Univ. of Goma, Congo, Univ. of Otago, New
Zealand and SAHMRI and WCHRI, Adelaide.
D13 I668.2
The Influence of Inflammation on Iron
Status among Young Children in the Dominican Republic and
Nicaragua. C.G. Perrine, M.E. Jefferds, A. Then, S. Santos,
R. Flores. Ctrs. for Dis. Control and Prevent. and Ministry of
Publ. Hlth., Santo Domingo.
D14 II668.3
Maternal Anemia of Inflammation and
Adverse Pregnancy and Neonatal Outcomes in India. J.L.
Finkelstein, A.V. Kurpad, T. Thomas, K. Srinivasan, C.
Duggan. Cornell Univ., St. John’s Res. Inst., Bangalore, Harvard
T.H. Chan Sch. of Publ. Hlth. and Children’s Hosp. Boston.
D15 I668.4
Micronutrients and Dengue Fever in
Coastal Ecuador. J.L. Finkelstein, A.J. Layden, E. BeltránAyala, W.B. Cárdenas, T.P. Endy, S.J. Ryan, A.M. Stewart
Ibarra, S. Mehta. Cornell Univ., Machala and Guayaquil,
Ecuador, SUNY Upstate Med. Univ. and Univ. of Florida.
D16 II668.5
HIV-Infected Pregnant and Lactating
Women Have Higher Serum Aflatoxin Levels Than HIVUninfected Women and Aflatoxin Levels Are Higher during
Early Postpartum Than during Pregnancy among HIV-Infected
Women. B.K. Natamba, J-S. Wang, S.L. Young, S. Ghosh,
J.K. Griffiths. Harvard Univ., Gulu Univ., Uganda, Univ. of
Georgia, Cornell Univ. and Tufts Univ.
D17 I668.6
Impact of Host Iron on Pathogenesis
of Falciparum Malaria: A Translational Field Study from the
Gambia. C. Cerami, M.M. Goheen, D. Gardner, B. Darboe, E.
Danso, M. Bah, A. Bah, R. Wegmuller, A. Prentice. Univ. of
North Carolina Sch. of Med., Med. Res. Council-The Gambia
and London Sch. of Hyg. and Trop. Med.
SUNDAYNUTRITION
D18 II668.7
Vitamin D Status and Diabetes among
Patients with Suspected Tuberculosis in Rural South India.
E.A. Yu, J.L. Finkelstein, W. Bonam, M.J. Glesby, D.G.
Russell, P.M. Brannon, S. Mehta. Cornell Univ., Arogyavaram
Med. Ctr., India, Weill Cornell Med. Col. and Col. of Vet. Med.,
Cornell Univ.
D19 I668.8
Overweight and Obesity Prevalence
Is High among Non-pregnant Women of Reproductive Age
in Eight Countries and Positively Associated with Circulating
Acute Phase Protein Concentrations. A.M. Williams, Y. Addo,
S. Namaste, P.S. Suchdev, R.C. Flores-Ayala. Emory Univ.,
Eunice Kennedy Shriver NICHD, NIH, Rockville, SPRING
Proj. and Helen Keller Intl., Washington, DC and Ctrs. for Dis.
Control and Prevent.
D20 II668.9
The Infant Gut Microbiome Is Associated
with Stool Markers of Macrophage and Neutrophil Activity. Z.
Pierce, N. Huda, R. Raqib, S. Ahmed, M. Zerofsky, D. Mills,
C. Stephensen. Univ. of California, Davis, icddr, Bangladesh
and USDA, Davis.
D21 I668.10 Infectious Disease and Inflammation
in the First 24 Months of Life and Emerging Risk Factors for
Metabolic Syndrome in Peruvian Infants. G. Lee, M. Kosek,
M. Paredes Olortegui, P. Yori, L.E. Caulfield. Tulane Univ.,
Johns Hopkins Univ. and AB Prisma, Iquitos, Peru.
D22 II668.11 Scant Interactions of Biomarkers of
Oxidative Stress and Anti-oxidation Defense with Those of
the Inflammatory Response among Preschool Children Form
the Western Highlands of Guatemala. M.J. Soto Méndez,
C.M. Aguilera, M.D. Mesa, M.C. Rico, L. Campaña-Martín,
V. Martín-Laguna, N.W. Solomons, K. Schuemann, A. Gil.
CeSSIAM, Guatemala, Ibero-American Nutr. Fndn. and Univ.
of Granada, Spain and Tech Univ. of Munich.
D23 I668.12 Oregano Essential Oil and Carvacrol
Reduce Cryptosporidium parvum Infectivity of HCT-8 Cells.
S. Gaur, T.B. Kuhlenschmidt, M.S. Kuhlenschmidt, J.E.
Andrade. Univ. of Illinois at Urbana-Champaign.
D24 II668.13 Caffeine
Consumption
and
Its
Association with Mitochondrial-Specific Oxidative Stress
in People Living with HIV in the Miami Adult Studies on HIV
Cohort. V. Ramamoorthy, A. Campa, S. Sales, M. Rubens, C.
Fleetwood, T. Stewart, G. Alvarado, H. Khan, J.P. Liuzzi, F.
George, M. Baum. Florida Intl. Univ. and Louis A. Johnson VA
Med. Ctr., Clarksburg, WV.
D25 I668.14
Viral Hepatitis Infections in Africa. T.C.
Oyesile, G.P. Einstein, O.F. Obidi, O.L. Tulp. Univ. of Sci. Arts
& Technol., Montserrat and Univ. of Lagos, Nigeria.
D26 II668.15 Acute versus Delayed Iron: Effect
on Red Blood Cell Iron Incorporation in Uncomplicated
Malaria. S.E. Cusick, M.K. Georgieff, R.O. Opoka, C. John,
S. Abrams, E. Mupere. Univ. of Minnesota, Minneapolis,
Makerere Univ., Uganda, Indiana Univ., Indianapolis and Univ.
of Texas at Austin.
669. GLOBAL NUTRITION: MEASURING AND
IMPROVING THE EFFECTIVENESS OF
NUTRITION PROGRAMS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D27 I669.1
Quasi-Experimental Feeding Study in
Patients Admitted for Elective Gastrointestinal Surgery at Bach
Mai Hospital, Hanoi, Vietnam. P.T.T. Huong, N.T. Lam, N.T.T.
T’hu, N.Q. Anh, T.H. Hoc, D.T.K. Lien, K. Gura, T.R. Ziegler,
K. Plourde, L.S. Young. Natl. Inst. of Nutr. and Bach Mai
Hosp., Hanoi, Boston Children’s Hosp., Emory Univ., Boston
Univ. Sch. of Publ. Hlth. and Boston Med. Ctr.
D28 II669.2
Lipid Profile, Glucose and Insulin Are
Affected Differently by Physical Activity, Nutrition Education or
Their Combination in Mexican Adolescents. R. Valdes-Ramos,
R.M. Velasco, P. Tlatempa-Sotelo, A.L. Guadarrama-López,
A.D. Benítez-Arciniega, B.E. Martínez-Carrillo. Fac. of Med.,
Autonomous Univ. of Mexico State, Toluca and Autonomous
Univ. of Chiapas, Mexico.
D29 I669.3
Contribution of School Meals to Nutrient
Intakes of School-Age Children Enrolled in Two Feeding
Programs in Ghana. J.S. Owusu, E. Colecraft, R. Aryeetey,
J.A. Vaccaro, F. Huffman. Florida Intl. Univ. and Sch. of Publ.
Hlth., Univ. of Ghana.
D30 II669.4 Child
Stunting
and
Maternal
Undernutrition in Two Rural Ethiopian Communities Five
Years after the Initiation of the National Nutrition Program.
G.E. Lombamo, C.J. Henry, N. Regassa, G.A. Zello. Col.
of Pharm. & Nutr., Univ. of Saskatchewan and Sch. of Nutr.,
Food Sci. & Technol. and Sch. of Envrn, Gender and Develop
Studies, Hawassa Univ., Ethiopia.
D31 I669.5 Barriers
for
Science
Outreach
Regarding Nutrition and Food Safety: A Qualitative Study of
Teenagers in Chongqing City, China. Z. Xiang, Y. Wang, T.
Song, J. Zhou, J. He, Y. Zhang. Chongqing Med. Univ., China
and Univ. at Buffalo, SUNY.
D32 II669.6
Development of a Survey That Assesses
Intra-and Inter-Personal Weight-Related Cognitions and
Behaviors of Mothers of Young Children. J.T. Martin-Biggers,
V. Quick, J. Worobey, C. Byrd-Bredbenner. Rutgers Univ.
D33 I669.7 HomeStyles:
Tracking
Participant
Progress in a Randomized Control Trial. C. Delaney, J.T.
Martin-Biggers, M. Koenings, C. Byrd-Bredbenner.
Rutgers Univ.
D34 II669.8 PROSPERA Program Impact on
Hemoglobin Concentration in Children Less Than Five
Years Old from San Luis Potosí State. T. Shamah Levy,
E.B. Gaona Pineda, L. Cuevas Nasu, I. Méndez Gómez
-Humarán, S. Villalpando Hernández. Natl. Publ. Hlth. Inst.,
Cuernavaca, Mexico.
D35 I669.9 Multisectoral Nutrition: Feasible or
Fantasy? D. Pelletier, S. Gervais, H. Hafeez-ur-Rehman, D.
Sanou, J. Tumwine. Cornell Univ.
195
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NUTRITIONSUNDAY
D36 II669.10 Evidence of Reporting Bias within the
Context of a Randomized Trial of Infant and Young Child Feeding
Messages in Rural Kenya. C.P. Stewart, A.M. Williams, B.F.
Arnold, J.M. Colford, H.N. Dentz, M. Kiprotich, R.O. Omondi,
B. Akoth, C. Null. Univ. of California, Davis, Emory Univ.,
Sch. of Publ. Hlth./Epidemiol., Univ. of California, Berkeley,
Innovations for Poverty Action, Kenya and Mathematica Policy
Res., Washington, DC.
D37 I669.11 “My Testimony Is the Growth of My
Baby”: Effectiveness of the Nutrition Improvement Program
on Infant and Young Child Feeding and Nutritional Status K.R.
Reinsma, G. Nkuoh, P.M. Tih. Cameroon Baptist Convention
Hlth. Svcs., Bamenda.
D38 II669.12 Impact of Micronutrient-Fortified Milk
Supplementation on Anthropometric Measures and Lipid
Profile on School Children in Quito, Ecuador. M. Fornasini,
D. Guevara, S. Reyes, M. López, I. Cocha, M. Morales, N.
Flores, S. Aguirre, M.E. Baldeon. Univ. of the Américas,
Ecuador, Nestle - Quito and NetLab, Quito.
D39 I669.13 Improving Nepal’s Female Community
Health Volunteers’ Infant and Young Child Feeding Exposure
and Knowledge: Results from Implementation Research on
the Suaahara Program. K. Cunningham, A. Singh, P. Menon,
R. Avula, P. Pandey Rana, P. Oyloe, S. Alayon. Independent
Consultant, U.K., Tufts Univ., IFPRI, New Delhi, Suaahara,
Kathmandu and Save the Children, Washington, DC.
D40 II669.14 The Role of Dairy in the Comparative
Effectiveness and Cost of Fortified Blended Foods versus
Ready-to-Use Foods in Treatment of Children with Moderate
Acute Malnutrition. D.J. Suri, D. Moorthy, I.H. Rosenberg.
Friedman Sch. of Nutr., Tufts Univ. and SPRING, Arlington, VA.
D41 I669.15 Scaling Up Dietary Data for DecisionMaking in Africa and Asia: New Technological Frontiers. J.
Coates, W.F.L. Bell, B. Colaiezzi, C. Cisse. Tufts Univ., Boston.
D42 II669.16 Dorwin Lajot’s Theory of Nutritional
Sedimentation Can Enlighten and Motivate Our Desire to
Manage Weight or Reduce Diabetes and Any Reverse Lifestyle
Related Diseases. D.Z. Lajot. DL NUTRITIONAL Consultancy
and Supply, Philippines.
D43 I669.17
Filling a Dietary Data Gap? Estimating
Individual Nutrient Intakes from Household-Level Data in
Ethiopia and Bangladesh. J. Coates, B. Rogers, A. Blau, J.
Lauer. Tufts Univ. Friedman Sch. of Nutr. Sci. and Policy.
D44 II669.18
Tubaramure, a Food-Assisted Integrated
Health and Nutrition Program, Improves Maternal Health and
Nutrition Knowledge in Burundi. E. Iruhiriye, J. Heckert, D.K.
Olney, J.L. Leroy, M. Ruel. IFPRI, Washington, DC.
670. GLOBAL NUTRITION: NUTRITIONSENSITIVE PROGRAMS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D45 I670.1
Effects of Text Message Intervention on
Infant Growth and Anemia at 6 and 12 Months Old. J. Lai, Y.
Duan, W. Jia, S. Jiang, X. Pang, Y. Bi, J. Wang, S. Yin, Z. Yang.
Natl. Inst. for Nutr. and Hlth., CDC, Beijing and Tuyou Qi CDC,
Baotou, China.
196
D46 II670.2 Physical, Economic, and Social
Limitations to Egg Consumption in the Luangwa Valley, Zambia.
J.J. Hong, E.B. Martey, S.E. Dumas, S.L. Young, A.J. Travis.
Cornell Univ.
D47 I670.3
Agricultural Interventions for Improved
Nutrition: A Review of Livelihood Dimensions. K.J. Fiorella,
R.L. Chen, E.M. Milner, L.C.H. Fernald. Cornell Univ.,
Univ. of California, Berkeley and Sch. of Publ. Hlth., Univ. of
D48 II670.4
Leveraging Food and Agriculture Policy
Mapping and Analysis for Nutrition-Sensitive Planning. J.
Meerman, M.C. Dode, C. Dufour. Food and Agr. Org. of the
U.N., Rome.
D49 I670.5 The Role of Women’s Status in
Agricultural Commercialization, Production Diversity and
Dietary Diversity in Ethiopia: Results from a 2012 National
Integrated Agriculture and Socio-economic Survey. J. Coates,
T. Galante. Tufts Univ. Friedman Sch.
671. MATERNAL, PERINATAL AND PEDIATRIC:
EARLY CHILDHOOD NUTRITION
Poster
Maternal, Perinatal and Pediatric RIS
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D50 II671.1
Growth and Tolerance of a Routine
Infant Formula with an Alternative DHA Source Fed to Term
Infants. A.C. Patterson, K.H. Maditz, C. Harris, J. Wampler,
A. Kirchoff, E. Zissman, C.L. Berseth. Mead Johnson Nutr.,
IN and Altamonte Pediat. Assocs., Lake Mary, FL.
D51 I671.2
Micronutrient Intake and Supplement
Use in Infants and Toddlers from a WIC Clinic in Puerto
Rico. K.Y. Amaro-Rivera, E. Ríos, O. Sinigaglia, B. Díaz,
M. Campos, C. Palacios. Grad. Sch. of Publ. Hlth., Sch. of
Nursing and Sch. of Dent. Med., Univ. of Puerto Rico Med. Sci.
Campus, San Juan.
D52 II671.3
The Correlation between Dairy Product
Consumption and Gastrointestinal Bleed, Ovarian Cancer,
and Diabetes in Infants: A Meta-analysis Approach. S.L.
Kelly-Newton, O.L. Tulp, G.P. Einstein. Univ. of Sci. Arts &
Technol., Montserrat.
D53 I671.4
Gastrointestinal Tolerance of Formula
Supplemented with Oligosaccharides. J. Kajzer, J. Oliver, B.
Marriage. Abbott Nutr.
D54 II671.5
Exclusive Breastfeeding Duration and
Risk of Anemia in Infants and Young Children. D. Li, F. Wang,
H. Liu, Y. Guan, T. Huang, J. Zheng. Zhejiang Univ., China,
Jiaxing, China, Boston, MA and Cambridge, U.K.
D55 I671.6 The
Importance
of
Vitamin A
Supplementation Dose, Frequency and Duration on All-Cause
Mortality in Children Under 5 Years. L. Pimpin, S. Kranz,
W. Fawzi, C. Duggan, D. Mozaffarian. Tufts Univ. Friedman
Sch. of Nutr. Sci. and Policy and Harvard T.H. Chan Sch. of
Publ. Hlth.
SUNDAYNUTRITION
D56 II671.7
The Effect of Zinc Supplementation
during Pregnancy and Youth on Child Growth Up to 5 Years:
A Systematic Review and Meta-analysis. L. Pimpin, E. Liu,
M. Shulkin, C. Duggan, W. Fawzi, D. Mozaffarian. Tufts Univ.
Friedman Sch. of Nutr. Sci. and Policy and Harvard T.H. Chan
Sch. of Publ. Hlth.
D57 I671.8
Nutrient and Food Group Intakes of the
Korean Preschoolers According to Growth Status. M. Kang,
J.E. Shim, H-Y. Paik. Col. of Human Ecol., Seoul Natl. Univ.
and Daejeon Univ., South Korea.
D58 II671.9
Public Health Monitoring of Weight
Change, in Addition to Weight Status, in Child Care Centers. J.
Stookey, L. Tao-Lew, T. Arana, J. Evans. San Francisco Dept.
of Hlth.
D59 I671.10 Nutrient Intakes from Restaurants
among U.S. Children Age 1-2 Years. A.B. Jarvis, J.C.
Clemens, D.G. Rhodes, A.J. Moshfegh. USDA, Beltsville, MD
and Amer. Soc. for Nutr., Bethesda.
D60 II671.11 Food
Sources
of
Fiber
and
Micronutrients of Concern in Diets of Young Children. L.M.
O’Neill, K.C. Reidy, D.M. Deming. Nestle Nutr., Florham
Park, NJ.
D61 I671.12 Portioning Foods and Beverages for
Toddlers and Preschool Children. E. Jacquier, A. Gatrell, A.
Bingley. Lancaster Univ., U.K.
D62 II671.13 Effect of Food Allergies on Growth in
Children. K. Rhodes, T. Crook, J. Phelps, R. Hakkak. Univ. of
Arkansas for Med. Sci.
D63 I671.14
Risk of Deficit in the Nutritional Status of
Children Hospitalized at Admission Vs More Than Seven Days.
E.M. Vasquez-Garibay, N.C. Muñoz-Esparza, E. RomeroVelarde, R. Troyo-Sanroman. Univ. of Guadalajara and Civil
Hosp. of Guadalajara.
D64 II671.15
Gamma EEG Activation during PictureWord Semantic Processing in 3 Year Olds Varies as a Function
of Gender and Infant Diet. R.T. Pivik, A. Andres, M.A. Cleves,
T.M. Badger. Arkansas Children’s Nutr. Ctr., Univ. of Arkansas
for Med. Sci.
D65 I671.16
Validation of a Novel Method for Use in
Studies of Iron Status, Brain Function (EEG), and Recognition
Memory Performance in Infancy. S.M. Stoyell, J.E.H. Nevins,
M.A. Orsillo, R.L. Canfield, S.S. Robertson, J.D. Haas.
Cornell Univ.
D66 II671.17 The Relationship between Infant Iron
Status, Maternal-Infant Interactions, and Cultural Ideology.
E.N. McNeill, J.E.H. Nevins, R.L. Canfield, J.D. Haas.
Cornell Univ.
D67 I671.18Omega-3
Deprivation
Enhances
Anxiety-Like Behaviors after Abstinence from Chronic Cocaine
Consumption: Possible Synergistical Effect of Cocaine and
Nutrition. S. Serrano, N. Rodriguez, J.R. Geste, M. Pompilus,
N. Wickensonn, C. Maldonado-Vlaar. Univ. of Puerto RicoRio Piedras Campus.
D68 II671.19
The Effect of Iron Deficient Diets (wIth or
without LC-PUFA) on the Offspring Brain Lipid and Eicosanoid
Metabolism during Pre-postnatal Development. F.M. Rioux,
J-L. Jougleux, M.E. Surette, S. Fiset. Sch. of Nutr. Sci., Univ.
of Ottawa, Cocagne, NB, Univ. of Moncton, Moncton and
Edmunston, Canada.
D69 I671.20
Maternal Diet Quality during Pregnancy
and Fetal Growth Outcomes: A Pilot Study of Lower-Income
Pregnant Women. C.W. Leung, E.S. Epel, N.R. Bush, K.
Coleman-Phox, N.E. Adler, B.A. Laraia. UCSF and Sch. of
Publ. Hlth., Univ. of California, Berkeley.
MEETING THE NUTRITIONAL NEEDS OF
PEDIATRIC POPULATIONS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D70 II672.1
Is It Useful and Practical to Assess Body
Fat in Sick Infants Using Skinfolds? C.M. Wright, S.A. Milani,
K. Gerasimidis. Sch. of Med., Univ. of Glasgow.
D71 I672.2
Lower Maternal Serum Folate in First
Trimester Associated with Higher Autism Risk in Offspring.
S. Sen, M. Siegel, M. Verdi, F.L. Lucas, L. Folger, W. Allan,
L. Paul, J. Selhub, S.L. Santangelo. Brigham and Women’s
Hosp., USDA at Tufts Univ., Tufts Univ. Sch. of Med., Maine
Med. Ctr. Res. Inst., Spring Harbor Hosp., Westbrook, ME and
Fndn. for Blood Res., Scarborough, ME.
D72 II672.3
Fatty Acid Composition in Feeds and
Plasma of Canadian Premature Infants. J. Friel, D. Mackay, Z.
Hossain. Univ. of Manitoba.
D73 I672.4 Impact of Breastfeeding on the
Nutritional Status of Infants with Cystic Fibrosis in the First
Year of Life – Results of the First Study. H. Lai, L. Chin, S.
Schoff, Z. Zhang, F.R. Greer. Univ. of Wisconsin-Madison.
MAMMARY GLAND FUNCTION AND EFFECTS
OF MILK COMPONENTS ON INFANT HEALTH
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D74 II673.1 Women with a Common Genetic
Variant in ZnT2 (T288S) Have Altered Breast Milk Composition:
Implications for Suboptimal Lactation. S. Lee, C. Dalrymple,
S.L. Kelleher. Penn State Hershey Col. of Med.
D75 I673.2
Effects of Consuming Bifidobacterium
longum Subspecies infantis on Intestinal Microbiota in
Exclusively Breastfed Term Infants. J.T. Smilowitz, A. Fineberg,
M. Underwood. Univ. of California, Davis, Sutter Davis Hlth.
and Univ. of California Davis Children’s Hosp., Sacramento.
D76 II673.3
The Participation of an Infant Harbored
Bacterial Commensal in Urea Nitrogen Salvaging. X. You, Y.
Lyu, D.A. Sela. Univ. of Massachusetts Amherst and Univ. of
Massachusetts Med. Sch.
D77 I673.4
Milk Osteopontin Regulates Immune
Responses in Mice Stimulated by Lipopolysaccharide. R.
Jiang, C. Prell, B. Lönnerdal. Univ. of California, Davis and
Dr. von Hauner Children’s Hosp., Univ. of Munich Med. Ctr.
D78 II673.5 Dietary Depletion of Cow’s Milk
MicroRNAs Impairs Fecundity in Mice. M. Sadri, F. Xie, J.
Wood, J. Zempleni. Univ. of Nebraska-Lincoln.
197
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NUTRITIONSUNDAY
D79 I673.6
Effect of Daily Iron Supplementation in
Healthy Exclusively Breastfed Infants: A Systematic Review
with Meta-analysis. C. Cai, J. Friel. Univ. of Manitoba.
D80 II673.7
Consumption of a Corn-Sugar Based
Infant Formula Is Associated with Higher C-Peptide Secretion
Compared to Lactose Based Formula among Exclusively
Formula Fed Infants. B.E. Young, M. Tang, K. Griese, N.F.
Krebs. Univ. of Colorado Sch. of Med.
D81 I673.8
Analysis of Maillard Reaction Products,
Carboxymethyllysine, Furosine, Hydroxymethylfurfural, Furan
and Acrylamide during Processing Infant Formula. H-M.
Lee, S-Y. Yang, K-W. Lee. Col. of Life Sci. and Biotechnol.,
Korea Univ.
D82 II673.9
A Dose-Response Balance Study to
Establish the Daily Dietary Iodine Requirement in Infancy. S.
Dold, M. Zimmermann, J. Baumgartner, C. Braegger, M.
Andersson. ETH Zurich, North-West Univ., South Africa and
Univ. Children’s Hosp. Zurich.
D83 I673.10 Human Milk Oligosaccharides in
Preterm and Term Milk. A.L. Morrow, C. Chen, A. Cline,
D.S. Newburg. Cincinnati Childrens Hosp. Med. Ctr. and
Boston Col.
674. COMMUNITY AND PUBLIC HEALTH NUTRITION:
COMMUNITY AND PUBLIC HEALTH
NUTRITION INTERVENSIONS
Poster
(Sponsored by: Community and Public Health
Nutrition RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D84 II674.1“Ignite: Sparking Youth to Create
Healthier Communities”–Policy Changes. K. Kattelmann, B.
Chen, A.M. Daniels, S. Zies, B. Stefura, N. Muturi, Y. Li, E.
Lindshield, T. Kidd. South Dakota State Univ., Ohio State
Univ. and Kansas State Univ.
D85 I674.2 Therapeutic Nutritional Effect of
Regular Ingestion of Non-caloric Sweeteners over Regular
Ingestion of Sucrose. I. Contreras, A.J. Diaz-Sanchez, J.
Gonzalez-Rangel, N. Guzman-Frias, M. Sanchez-Delgado,
J.A. Estrada. Autonomous Univ. of Mexico State, Toluca.
D86 II674.3 Tracking Change in Homestyles:
Developing a Goal Tracker for Parents of Preschool-Aged
Children. C. Delaney, J.T. Martin-Biggers, C. Lozada, G.
Povis-Alleman, N. Hongu, J. Worobey, C. Byrd-Bredbenner.
Rutgers Univ. and Univ. of Arizona.
D87 I674.4 Factors Affecting Enrollment in a
Nutrition Intervention Program for Low-Income Mothers. S.
Nitzke, M-W. Chang, R. Brown, M.J. Egan, C. Bendekgey,
D. Buist. Univ. of Wisconsin-Madison, Michigan State Univ.,
Dept. of Hlth. and Human Svcs., Lansing, Kent Cty. Hlth. Dept.,
Grand Rapids and Calhoun Cty. Publ. Hlth., Battle Creek.
D88 II674.5
Anemia Prevalence and Hemoglobin
Concentrations Improve in Young Children after 6 Months of
Supplementation with a 21 Micronutrient-Fortified Cereal and
Legume Premix in a Rural Community in Retalhuleu, Guatemala.
G.A. Reinhart, A.M. Palacios, S. de Ponce, V. Alfonso. The
Mathile Inst., Dayton and APEVIHS, Retalhuleu, Guatemala.
198
D89 I674.6
Kuwaiti Mother’s Perception of Her 3-5
Year Old Child’s Body Mass Index. G. Alabdullah, D. Abel, L.
Shaban, F. Huffman. Florida Intl. Univ. and Kuwait Univ. Col.
of Life Sci.
D90 II674.7
Risky Food Handling Practices among
Community-Residing Older Adults. L. Yap, S.L. Francis, M.
Shelley, C. Lillehoj, D. Montgomery, D.M. Winham. Iowa
State Univ. and Iowa Dept. of Publ. Hlth., Des Moines.
D91 I674.8
Assessing Knowledge, Attitudes, and
Practices Concerning Sodium Intake in College Students. A.
Webster, C. Gibby, C. Gunther, E. Lim, A. Rose, J. Banna.
The Ohio State Univ. and Univ. of Hawaii at Manoa.
D92 II674.9
Food Assistance Programs Impact on
Dietary Diversity in Children of San Luis Potosi, Mexico. E.B.
Gaona-Pineda, I. Mendez-Gomez-Humaran, L. CuevasNasu, T. Shamah-Levy. Natl. Inst. of Publ. Hlth., Cuernavaca
and Ctr. for Res. in Math., Aguscalientes, Mexico.
D93 I674.10 Preliminary Data from an EvidenceBased Nutrition Education and Cooking Family Meals Program
for Moderately Low-Income Families with Children Aged 4-10
Years Old. C.A. Rogers, K. Pratt, J. Kennel, C. Gunther. The
Ohio State Univ.
D94 II674.11
Effect of Prospera Program in Nutritional
Status in Its Beneficiaries in San Luis Potosi State, Mexico.
L. Cuevas Nasu, T. Shamah-Levy, E.B. Gaona-Pineda, I.
Mendez-Gomez. Natl. Inst. of Publ. Hlth., Cuernavaca, Mexico.
D95 I674.12 Changes in Intake of CVD-Related
Food Components Associated with an Intervention to Reduce
Sedentary Time. K. Casey, S. Rosenkranz, E. Mailey,
A. Baquero Garcia, A. Swank, R. Rosenkranz. Kansas
State Univ.
D96 II674.13
Egg and Dairy Consumption Were Not
Associated with Allergic Reactions or Allergy-Like Symptoms
in 6 to 9 Month-Old Infants from Rural Cotopaxi, Ecuador. A.M.
Palacios, C.A. Gallegos, W.F. Waters, C. Malo, C. Lutter,
C.P. Stewart, G.A. Reinhart, L.A. Iannotti. The Mathile Inst.,
Dayton, OH, Univ. of Texas at Austin, Washington Univ. in St.
Louis, Univ. San Francisco de Quito, Pan Amer. Hlth. Org./
WHO, Washington, DC and Univ. of California, Davis.
D97 I674.14
Application of the New “Guidelines, for
Sale and Distribution of Prepared and Processed Foods and
Beverages in Schools” in the National School System, during
the Lunch in Mexico. M.C. Morales Ruán, T. Shamah-Levy, A.
Jimenez-Aguilar. Natl. Inst. of Publ. Hlth., Mexico City.
D98 II674.15 Meal Consumption Patterns among
Recipients of the School Nutrition Programme in Trinidad and
Tobago. M. Francis, S. Nichols. Natl. Dietary Svcs. Ltd. and
Univ. of The West Indies, Trinidad and Tobago.
D99 I674.16 Follow of Children and Youth People
with Type 1 Diabetes after Five Years of Participation in a SelfCare Program in Hermosillo, Mexico. P.E. Landeros Flores,
G.E. Portillo, A.D. Contreras, E.E. Artalejo, M.N. Ballesteros,
J. Krimpe, M. Ortega Ctr. for Food Res. and Develop. (CIAD)
and Univ. Vizcaya de las Américas, Hermosillo, Mexico.
D100 II674.17 Relationship between Breast Feeding
and Eating Patterns in a Rural, Mexican-Origin Population
during a Nutrition Intervention. R. Cabrera, A.L. Aguilera, A.
de la Torre, L.L. Kaiser. Univ. of California, Davis.
D101 I674.18
Evaluation of a Multi-component Farmto-Preschool Program on Access to and Consumption of Fruits
and Vegetables among Preschool-Aged Children. J. Parry, M.
Spence, K. Aaron, S. Colby, K. Kavanagh. Univ. of Tennessee
and East Tennessee Children’s Hosp., Knoxville.
SUNDAYNUTRITION
D102 II674.19 Why Are Communities So Committed
to Providing Non-governmental Food-Assistance Programs?
E.M. Fishbein Androlia, E.A. Frongillo, C.E. Blake, C.
Shapiro. Univ. of South Carolina.
D103 I674.20 How Effective Is the “Eat Better Feel
Better” Community-Based Cooking Intervention at Tackling
Barriers of Time, Cost, Waste and Knowledge of Healthy
Eating in Glasgow, Scotland? A.L. Garcia, R. Reardon, E.
Hammond, A. Parrett, A. Gebbie-Diben. Univ. of Glasgow
and NHS Greater Glasgow and Clyde.
D104 II674.21 Characterization of Fatty Acid and
Mineral Composition of Selected Seeds, Nuts and Oils in
Tanzania. K. Valentini, T. Jumbe, A. Pickens, M. Adjepong,
W. Li, J. Kinabo, J. Fenton. Michigan State Univ. and Sokoine
Univ. of Agr., Tanzania.
D105 I674.22 Does
Installing
“Healthy
Eating
Information” in a University Dining Hall Change Students’ Food
and Beverage Choices? M.J. Scourboutakos, C.L. Mah, S.
Murphy, F. Mazza, M.R. L’Abbe. Fac. of Med., Univ. of Toronto
and Fac. of Med., Mem. Univ. of Newfoundland, Canada.
D106 II674.23 Use of Monitoring Data to Inform
Program Implementation of a Multiple Micronutrient Powders
Program in Bihar, India. R. Mehta, M. Young, P. Verma, P.
Kekre, A. Webb Girard, U. Ramakrishnan, S. Babu, I. Devi, D.
Nawal, R. Verma, A. Kumar, S. Alam, S. Ranjan, A. Swarup,
I. Chaudhuri, S. Srikantiah, R. Martorell. Emory Univ. and
CARE India, Patna.
D107 I674.24 Self-Reported Barriers to Adapting
Contextualized Nutrition Education Messages Targeted at
Preventing Iron Deficiency among Mothers and Their Young
Children in Ghana. B.A.Z. Abu, V.L. Louw, J.E. Raubenhiemer,
W. Oldewage-Theron, L.V. van den Berg. Texas Tech Univ.
and Fac. of Hlth. Sci., Univ. of the Free State, South Africa.
D108 II674.25
Feasibility and Acceptability of a Novel
Intervention to Improve Infant and Young Child Feeding
Counseling for HIV-Positive Women in Malawi. V. Flax,
G. Hamela, I. Mofolo, L. Mokiwa, P. Mgoli, H. Swira, M.
Hosseinipour, I. Hoffman, S. Maman. Univ. of North Carolina
at Chapel Hill, RTI Intl., Durham, NC and UNC Project-Malawi
and CARE-Malawi, Lilongwe.
D109 I674.26 Improvement in Long-Term Household
Food Security among Indiana Households with Children Did Not
Differ between Rural and Urban Counties after a Supplemental
Nutrition Assistance Program-Education Intervention. R.L.
Rivera, M.K. Maulding, A.R. Abbott, Q. Wang, H.A. EicherMiller. Purdue Univ.
D110 II674.27 Improving Accessibility and Quality of
Nutrition and Health Care in Kamuli District, Uganda. D.M.
Winham, D. Masinde, L. Byaruhanga, G. Nonnecke, M.
Rothschild. Iowa State Univ.
D111 I674.28
Attention to Front-of-Package Labels Is
Associated with Parents’ Healthy Food and Beverage Choices
for Their Children. N.N. Monalisa, T.N. Rosemond, J.F.
Thrasher, J. Kim, C.E. Blake. Univ. of South Carolina.
D112 II674.29 Feasibility of an Online Nutrition
Education eLearning Program from the Perspectives of Peer
Nutrition Educators and Low-Income Individuals in Georgia. S.
Stotz, J.S. Lee, H. Rong. Univ. of Georgia.
D113 I674.30
Healthy Store Programs and WIC, but
Not SNAP, Are Associated with Corner Store Healthfulness.
R. DeWeese, M. Todd, A. Karpyn, M. Yedidia, M. Kennedy,
M. Bruening, C. Wharton, P. Ohri-Vachaspati. Arizona State
Univ., Phoenix, Univ. of Delaware and Rutgers Univ.
D114 II674.31 Tools for Communication of Exercise
Health Benefits: EPA’s BenMAP and ArcGIS Show Very
Granular Walking and Cycling Impacts. A.J. DeLucia. East
D115 I674.32 Wellness Program at the Workplace
Promotes Healthy Eating Lifestyle: Analysis of Employee
Wellness Data in a Longitudinal Retrospective Study. G.A.
Soliman, J. Kim, J-M. Lee, R. High, N.K. Wehbi, J.T. Canedy.
Univ. of Nebraska Med. Ctr., Univ. of Nebraska Omaha and
Nebraska Med., Omaha.
D116 II674.33 The Impact of a Pricing and
Communications Intervention on Stocking and Sales of
Healthier Foods in Small Baltimore City Food Stores. N. Budd,
A. Kharmats, J.K. Jeffries, J. Jones-Smith, J. Gittelsohn.
Johns Hopkins Sch. of Publ. Hlth. and Univ. of North Carolina
at Chapel Hill.
D117 I674.34 Vitamin A Fortification of Vegetable
Oil in Bangladesh. R. Raghavan, G.J. Aaron, L.M. Neufeld,
S. Rahman, B. Nahar, J. Knowles. Johns Hopkins
Bloomberg Sch. of Publ. Hlth., Global Alliance for Improved
Nutr., Geneva and Dhaka and Intl. Ctr. for Diarrhoeal Dis.
Res.,Dhaka, Bangladesh.
D118 II674.35 Expectations from Low-Income Adults
Regarding an Innovative Nutrition Education eLearning
Program. S. Stotz, J.S. Lee, J. Hibbs, A. White. Univ.
of Georgia.
D119 I674.36 Development of an Online Nutrition
Education Elearning Program Targeted to SNAP-Ed Eligible
Adults. S. Stotz, J.S. Lee, H. Rong, A. Childers. Univ.
of Georgia.
D120 II674.37 Recruitment Strategies Implemented
across a Four-State Lifestyle Intervention: Get Fruved Study.
M.L. Barr, M.D. Olfert, W. Zhou, K. Riggsbee, A.E.W.
Mathews, M. Vilaro, K.K. Kattelmann, H. Andrea, A. White, T.
Horacek, T. Kidd, O. Brown, S.E. Colby. West Virginia Univ.,
Univ. of Tennessee, Knoxville, Univ. of Florida, South Dakota
State Univ., Univ. of Maine, Syracuse Univ., Kansas State Univ.
and Auburn Univ.
D121 I674.38
Multi-micronutrient Fortified Juice Drink
Improved Biomarkers of Iron Status among Schoolchildren: An
Intervention Study. I. Angeles-Agdeppa, M.E. Crisostomo,
C.R. Magsadia. Food and Nutr. Res. Inst., Taguig City,
Philippines and Univ. of the Philippines Manila.
D122 II674.39 Front-of-Pack Labelling Is Positively
Associated with Degree of Product Processing and Innovation.
A. Christoforou, V. Tarasuk. Univ. of Toronto.
D123 I674.40
A Qualitative Study of Factors Related
to Cardiometabolic Risk in Rural Men. M.L. Graham, E.H.
Morgan, R.A. Seguin. Cornell Univ.
D124 II674.41 Food Label Use Is Associated with
Dietary Quality and Dietary Patterns among Latinos with Type
2 Diabetes. G. Kollannoor Samuel, S. Segura-Pérez, F.M.
Shebl, N. Hawley, G. Damio, J. Chhabra, S. Vega-López,
M.L. Fernandez, R. Pérez-Escamilla. Yale Sch. of Publ. Hlth.,
Hispanic Hlth. Council, Hartford, CT, Hartford Hosp., Sch.
of Nutr. and Hlth. Promotion, Arizona State Univ. and Univ.
of Connecticut.
D125 I674.42
The Formulation of a Patient-Centered
Quality Care Improvement Tool for Nursing Home Patients.
S.G. Henry-Newton, G.P. Einstein, O.L. Tulp. Univ. of Sci. Arts
& Technol., Montserrat.
199
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675. INNOVATIONS IN UNDERGRADUATE AND
GRADUATE NUTRITION EDUCATION
Poster
(Supported by Association of Nutrition Departments and
Programs )
Assoc. of Nutrition Departments and Programs
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D126 II675.1
Development of a Nutrition Entrustable
Professional Activity for Pediatric Residents. A.J. Manders,
K.A. Ireland, D.J. Schumacher, S.B. Collier, C.L. Distler,
C.M. Lenders. Boston Med. Ctr., Cincinnati Children’s Hosp.
Med. Ctr. and Boston Children’s Hosp.
D127 I675.2 Assessing the Nutrition Curriculum
at Boston University School of Medicine. K.A. Ireland, A.
Manders, C. Lenders. Boston Med. Ctr. and Boston Univ. Sch.
of Med.
D128 II675.3
Mapping Nutrition Competencies in
the Foundation Years (Years 1 and 2) in Four Australian
Medical Courses Using an Online Curriculum Mapping Tool. C.
Nowson. Deakin Univ., Australia.
D129 I675.4
Understanding Nutrition-Related Care
in General Pediatric Outpatient Clinical Settings from the
Pediatric Provider Perspective: A Qualitative Study. J.L. Kaar,
S. Schievelbein, P. Gonzalez-Pacheco, K. Caponigro, A.
Graham, L.S. Goodell, D.A. Thompson. Univ. of Colorado,
Aurora, Metropolitan State Univ., CO and North Carolina State
Univ.
D130 II675.5
Assessment of Omega-3s Knowledge
on Blood Lipids among Registered Dietitians. C. Li, D. PalmerKeenan. Rutgers the State Univ. of New Jersey.
D131 I675.6
Changes in Perceptions of Nutrition
and Obesity in an Interdisciplinary Graduate Course. A.C.
Berg, W.E. Bignell, K.W. Shollenberger, M.A. Johnson. Univ.
of Georgia.
D132 II675.7
Cooking Meals More Frequently, Eating
More Fruits and Vegetables, and Less Fast-Foods among
Students in Nutritional Sciences Majors Than Non-majors.
B.R. Taylor, B.T. Pope, A.M. Franklin, P.R. Harris, B. Wyatt,
N. Hongu. Univ. of Arizona.
D133 I675.8
Improvements in Conscious Eating
Behaviors in Undergraduate Nutritional Science Students.
A.M. Franklin, B.T. Pope, B.R. Taylor, P.R. Harris, B. Wyatt,
N. Hongu. Univ. of Arizona.
D134 II675.9 Practical Usage and Educational
Requirement Analysis about School Meal Menu of Middle
Schools in Incheon Region. Y.A. Kim, S-K. Kang. Inha Univ.
and Inha Univ. Grad. Sch. of Educ., South Korea.
D135 I675.10 The Influence of Korean High School
Students’ Midnight Snacks on Their Breakfast-Skipping
Pattern. Y.A. Kim, J-H. Kim. Inha Univ. and Grad. Sch. of
Educ., Inha Univ., South Korea.
D136 II675.11
Integrating Food Insecurity Assessment
in Medical School Curriculum as an Important Health Indicator.
V. Uhley, A.C. Farr. Oakland Univ. William Beaumont Sch.
of Med.
200
D137 I675.12 Current Nutrition Screening and
Assessment Practices in Use According to Members of the
Texas and Arkansas Academy of Nutrition and Dietetics. T.
Hurlimann, J. Phelps, T. Crook, R. Hakkak. Univ. of Arkansas
for Med. Sci.
D138 II675.13 Synchronous Classrooms: Teaching
Practicing Nutrition Clinicians through Distance Technologies.
R. Heuberger, A. Clark, J. Logomarsino, V. Shayna, S.
Hewlings, D. Duriancik. Central Michigan Univ., Midland, MI,
The Villages, FL and Mt. Pleasant, MI and East Tennessee
State Univ.
D139 I675.14 Interprofessional Clinical Training of
Nutrition and Dental Students/Residents: Examining DrugNutrient/Dietary Supplement Interactions and Their Impact
on Diet/Nutrition and Oral Health. J. Ziegler, E. Spivack, G.
Heir, D. Rigassio Radler, R. Touger-Decker. Rutgers Sch. of
Dent. Med.
D140 II675.15Experiential
Learning
in
the
Undergraduate Nutrition Didactic Curriculum: Enhancing
Student’s Ability to Link Experience with Competencies
Achieved. M.I. Scannavino. Cedar Crest Col., PA.
D141 I675.16
Monitoring General Education Science
Competencies through a Beginning Nutrition Course: Step 1,
Development of Items for a Brief Assessment Quiz. A.D. Fly, L.
Kurz. Indiana Univ.
676. NUTRITION EDUCATION: NUTRITION
EDUCATION AND BEHAVIOR CHANGE
Poster
(Sponsored by: Nutrition Education and Behavioral
Science RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D142 II676.1
The Impact of Socio-economic Factors
and Food Habits on Lipid Profile: A Cross Sectional Study
among Schoolchildren from a Low-Income Area of Mexico.
D. Gregori, G. Lorenzoni, N. Soriani, P. Berchialla. Univ. of
Padova and Univ. of Turin.
D143 I676.2
PAWS (Peer-Education about Weight
Steadiness) Club: Rationale and Design for a Randomized
Controlled Study. H. Muzaffar, S. Nickols-Richardson. Univ.
of Illinois at Urbana-Champaign.
D144 II676.3
Self-Weighing and Visual Feedback
Has Long Term Effects on Weight Gain Prevention in Adults.
L. Wilkinson, C. Pacanowski, D. Levitsky. Cornell Univ. and
Neuropsychiat. Res. Inst., Ithaca.
D145 I676.4
The Supplemental Nutrition Assistance
Program Education Elementary School Students Had SelfReported and Observed Behavior Changes. L. McCullough,
V. Farrell, V. Hartz, T. LeGros, L. Jacobs, S. Misner. Univ. of
Arizona and UA Nutr. Network.
D146 II676.5
Pilot Study for Assessing Moderate to
Long-Term Outcomes of the Expanded Food and Nutrition
Education Program. G. Auld, S. Baker, J. Batchelder.
Colorado State Univ.
D147 I676.6
An Evaluation on Satisfaction with
Nutrition Counseling for Cancer Inpatients. A-C. Tung, C-F.
Wen, P-R. Li. Tungs’ Taichung MetroHarbor Hosp., Taiwan.
SUNDAYNUTRITION
D148 II676.7 Lessons
Learned
from
the
Development of a Prenatal Nutrition Online Training for EFNEP
Paraprofessional Nutrition Educators. S. Baker, G. Auld, M.
Chlipalski. Colorado State Univ.
D149 I676.8 Nutrition
Education
for
Obese
Emergency Department Patients. W-J.J. Yen, K. Horinko, B.
Meggs, K. Myers. Indiana State Univ. and East Carolina Univ.
D150 II676.9Nutritional
Awareness
about
Recommendations and Sources of Fruits and Vegetables in
Male Brazilian Adolescents and Association with Physical
Activity Patterns, Nutritional Status and Household
Characteristics – The Fit Food Study. R.H.V. Machado, I.
Iglesia, C.A. Hartwick, A. Pires, M. Fisberg, L. Moreno.
Sabara Children’s Hosp., José Luiz Egydio Setubal Fndn., São
Paulo, Univ. of Zaragoza, Spain, Danone Res. and Danone
Inst. Intl., Paris and Fed. Univ. of São Paulo.
D151 I676.10 Effects of an Educational Group
Intervention for Patients with Type 2 Diabetes on Lifestyle
and Glycemic Control. L.M. Sterpone, K. Haua-Navarro, A.B.
Perez-Lizaur. Univ. Iberoamericana, Mexico City.
D152 II676.11 Evaluating the Young Adult Motivation
to Prepare Healthy Foods Questionnaire Using Exploratory
Factor Analysis. A.D. Bailey, D. Miketinas, M. Cater, B.
Zawodniak, G. Tuuri. LSU and LSU AgCtr.
D153 I676.12
Influences on Fluid Intake According to
Preferences, Parental Permission and Nutritional Awareness
among Male Brazilian Teens – The Fitfood Study. R.H.V.
Machado, I. Iglesia, C. Martinelli, A.C.L. Rocha, C.A.
Hartwick, A. Pires, M. Fisberg, L. Moreno. Sabara Children’s
Hosp./José Luiz Egydio Setubal Fndn., São Paulo, Univ. of
Zaragoza, Spain, Danone Res. and Danone Inst. Intl., Paris
and Fed. Univ. of São Paulo.
D154 II676.13 Experiential Cooking and Nutrition
Education Program Improves Fruit and Vegetable Liking,
Vegetable Consumption, and Cooking at Home in Elementary
and Middle School Children. N.K. Edens, S. Sharma, S.
Folkens, A. Wojtowicz, N. Ranjit, A. Evans. Common Threads
and Univ. of Texas Sch. of Publ. Hlth., Austin.
677. NUTRITIONAL EPIDEMIOLOGY: ADVANCING
NUTRITIONAL EPIDEMIOLOGY WITH PUBLIC
USE AND COMMERCIAL DATA SETS
Poster
(Sponsored by: Nutritional Epidemiology RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D155 I677.1
Prevalence of Excess Sodium Intake
in the United States, NHANES 2009-2012 S.L. Jackson, S.
Coleman King, L. Zhao, M.E. Cogswell. Ctrs. for Dis. Control
and Prevent,
D156 II677.2 Consumption
of
Rice
Products
Containing Low Levels of Arsenic and Its Relationship to
Health Outcomes Utilizing Blood Pressure Readings: An Initial
Analysis of NHANES Data. L.A. Fahnestock, R.D. Smith, M.
Randhawa, G. Siapco, S. Soret, J. Lloren, J. Sabate. Loma
Linda Univ.
D157 I677.3
Usual Coffee Intake among Adults in
the United States. E. Loftfield, N.D. Freedman, Q. Xiao, K.W.
Dodd, R. Sinha, B.I. Graubard. NCI, NIH, Rockville, MD.
D158 II677.4
Sandwich Consumption in the U.S.:
Contributions to Intake and Associations with Dietary Quality
among Adults, What We Eat in America, NHANES 2009-2012
R.S. Sebastian, C. Wilkinson Enns, J.D. Goldman, A.J.
Moshfegh. USDA, Beltsville, MD.
D159 I677.5 DHA and EPA Consumption from
Seafood, U.S. Adults, 2009-2012 S.J. Nielsen, K.A. Herrick,
C.L. Ogden. Natl. Ctr. for Hlth. Stats., CDC, Hyattlville, MD.
D160 II677.6
Children (2-18 y) Consuming Flavored
Milk Ingested More Milk and a Higher Percentage Met
Dietary Recommendations for Calcium Than Non-consumers:
NHANES 2001-2012 C.E. O’Neil, T.A. Nicklas, V.L. Fulgoni
III. LSU Agr. Ctr., Baylor Col. of Med. and Nutr. Impact LLC,
Battle Creek, MI.
D161 I677.7
Characterizing Sandwich Consumption
Patterns among Children Age 2-19 Years, What We Eat in
America NHANES 2009-2012 K. Hoy, J.D. Goldman, R.S.
Sebastian, C. Wilkinson Enns, A.J. Moshfegh. USDA,
Beltsville, MD.
D162 II677.8
A Descriptive Study of the Vital Health
Indicators of Four Sub-Saharan African Countries, 19602012 S.S. Klobodu, J.A. Dawson, D.B. Reed, N. MoustaidMoussa, C. Carpio, N. Velikova. Texas Tech Univ.
D163 I677.9
Collecting Brand and Product Names in
the USDA Automated Multiple Pass Method 24-Hour Dietary
Recall. L.C. Steinfeldt, A.J. Moshfegh. USDA, Beltsville, MD.
D164 II677.10 Diet Quality during Pregnancy Is
Inversely Associated with Prepregnancy Weight Status. D.
Shin, K.W. Lee, W.O. Song. Michigan State Univ.
D165 I677.11 Eating Dessert Foods: Behavioral
Patterns in American Children. E.F. Jacquier, A.L. Eldridge.
Nestlé Res. Ctr., Florham Park, NJ and Lausanne.
D166 II677.12 Away-from-Home Food Intake among
Mexican Children Ages 2-13 Years. M.C. Afeiche, L. Smith
Taillie, A.L. Eldridge, B.M. Popkin. Nestlé Res. Ctr., Lausanne
and Univ. of North Carolina at Chapel Hill.
D167 I677.13 Beverage Choices among Adults and
Their Contribution to Nutrient Intake. E. Parker, J. Clemens, A.
Moshfegh. USDA, Beltsville, MD.
D168 II677.14 A Comprehensive Database Linking
Dietary Fibers and Health: Rationale and Methods. K.A.
Livingston, M. Chung, C.M. Sawicki, B.J. Lyle, D.D. Wang,
S.B. Roberts, N.M. McKeown. USDA at Tufts Univ., Tufts
Univ. Sch. of Med., Intl. Life Sci. Inst., Washington, DC and
Friedman Sch. of Nutr. Sci. and Policy, Tufts Univ.
D169 I677.15 School
Lunch
Consumption
Is
Associated with Higher Intakes of Total Fat, Added Sugars,
and Sodium in U.S. Children. B. O’Brien, J.A. Vernarelli.
Fairfield Univ.
D170 II677.16 Ready-To-Eat Cereal Consumption
Is Associated with Improved Nutrient Intakes and Nutrient
Adequacy in Lower Income Children and Teens: Results from
NHANES 2007-2012 C.K. Gugger, S. Bidwai, N. Joshi, N.M.
Holschuh. Gen. Mills Inc., Minneapolis and Mumbai.
D171 I677.17
Consumption
of
Low-Calorie
Sweeteners in the United States 2011-12 A.C. Sylvetsky,
Y. Jin, J.A. Welsh, K.I. Rother, S.A. Talegawkar. George
Washington Univ., Emory Univ. and NIDDK, NIH.
201
S
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NUTRITIONSUNDAY
D172 II677.18
Current Data on Manganese in Foods
and in U.S. Diets from the U.S. Food and Drug Administration’s
Total Diet Study. J.H. Spungen, R. Pouillot, D. HoffmanPennesi, S. Briguglio, M. Wirtz. USDA, College Park, MD.
D173 I677.19
Medium and High Risk Alcohol Drinking
Increases the Risk of Obesity in Korean Men: Prospective
Cohort Analysis Based on the National Health Insurance Data.
C-i. Kim, S-O. Kwon. Korea Hlth. Industry Develop. Inst.,
Chungbuk, South Korea.
D174 II677.20 Does the Nutrient Profile of Snacks
Vary According to the Time of Day of Consumption? S.A.
McNaughton, R. Leech, A. Worsley. Deakin Univ., Australia.
678. AGING: NUTRITION AND
MUSCULOSKELETAL HEALTH
Poster
(Sponsored by: Aging and Chronic Disease RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D175 I678.1 Higher Dietary Vitamin C Intake
Is Associated with Higher Grip Strength in Adults: The
Framingham Offspring Study. S. Sahni, P.F. Jacques, A.B.
Dufour, D.P. Kiel, R.R. McLean, M.T. Hannan. Harvard Med.
Sch. and USDA at Tufts Univ.
D176 II678.2
Magnesium and Space Flight. S.M.
Smith, S.R. Zwart. NASA and USRA, Houston.
D177 I678.3
Skeletal Muscle Specific MicroRNA 206
and 486 Observed in Circulation Are Biomarkers of Aging. L.M.
Margolis, Y. Ezzyat, R.A. Fielding, D.A. Rivas. Tufts Univ.,
Boston and USDA at Tufts Univ.
D178 II678.4
Mediterranean-Style Dietary Pattern Is
Associated with Hip Bone Mineral Density among Older Puerto
Rican Adults. S.E. Noel, S.J. Bigornia, K.M. Mangano, K.L.
Tucker. Univ. of Massachusetts Lowell.
D179 I678.5 Effect of Soy-Dairy Protein Blend
Ingestion on Post-exercise Muscle mTORC1 Signaling and
Protein Synthesis in Older Adults. M. Borack, P. Reidy, S.
Husaini, M. Markofski, R. Deer, A. Richison, B. Lambert, M.
Cope, R. Mukherjea, K. Jennings, E. Volpi, B. Rasmussen.
Univ. of Texas Med. Branch and DuPont Nutr. and Hlth.,
St. Louis.
D180 II678.6 Protein Intake and Bone Mineral
Density – A Systematic Review and Meta-analysis of
Randomized Controlled Trials. M. Shams-White, J. Sackey, Z.
Fu, M. Karlsen, M. Du, K. Insogna, M. LeBoff, S. Shapses,
C. Weaver, M. Chung. Tufts Univ., Yale Univ., Harvard Univ.,
Rutgers Univ. and Purdue Univ.
D181 I678.7
Blueberry
Diet
Derived
3-(3-Hydroxyphenyl) Propionic Acid Suppresses Osteoblastic
Cell Senescence to Promote Bone Accretion in Mice. J-R.
Chen, O.P. Lazarenko, M.L. Blackburn. Arkansas Children’s
Nutr. Ctr. and Univ. of Arkansas for Med. Sci.
D182 II678.8
Exercise or Caloric Restriction Reduces
Bone Resorption and Improves Cortical Bone Strength in
Hyperphagic OLETF Rats. L.C. Ortinau, M. Richard, M.
Linden, R.S. Rector, P. Hinton. Univ. of Missouri-Columbia.
202
D183 I678.9
Effects of a High-Fat, High-Cholesterol
Diet or Hyperphagia on Bone Mass, Bone Strength and
Serum Turnover Markers in Male Rats. L.C. Ortinau, M.
Richard, R. Dirkes, M. Linden, R.S. Rector, P. Hinton. Univ.
D184 II678.10
Short-Term Consumption of Whole Grain
Foods Independent of Weight Loss Does Not Affect Surrogate
Markers of CVD. M. Meydani, M. Thomas, J.B. Barnett, S.
Vanegas, O. Chen, G. Dolnikowski, S. Jonnalagadda, E.
Saltzman, S. Roberts, S.N. Meydani. USDA at Tufts Univ. and
Gen. Mills.
D185 I678.11
Insulin Resistance Negatively Influences
the Muscle-Dependent Relationship between IGF-I and Bone
Mass in Pre-menarcheal Girls. J. Kindler, N. Pollock, E. Laing,
N. Jenkins, A. Oshri, C. Isales, M. Hamrick, R. Lewis. Univ. of
Georgia and Augusta Univ.
D186 II678.12
Effects of a 12-Month Low-Carbohydrate
Diet versus a Low-Fat Diet on Bone Mineral Density: A
Randomized Controlled Trial. T. Hu, L. Yao, L. Bazzano.
Tulane Univ. and Univ. of Minnesota, Minneapolis.
D187 I678.13 Oral Potassium (K+) Administered as
K+ Enriched Diet Combined with a Specially Prepared K+
Rich Food-Based Supplement Reduces Pain in Rheumatoid
Arthritis. T.M. Kianifard, M.S. Saluja, A. Venugopalan, A.
Chopra. Ctr. for Rheumat. Dis., Pune, Iran.
D188 II678.14 Improved Muscle Function after Diet
Intervention with Leucine-Enriched Whey and Antioxidants in
Antioxidant-Deficient Aged Mice. M. van Dijk, F. Dijk, A. van
Bunschoten, D. van Dartel, K. van Norren, S. Walrand,
M. Jourdan, S. Verlaan, Y. Luiking. Nutricia Res., Utrecht,
Wageningen Univ., Netherlands and Univ. d’Auvergne, France.
D189 I678.15 Exercise-Induced Muscle Damage in
Healthy Men with Low Choline Intake. M. Kohlmeier, O. Dong.
UNC Nutr. Res. Inst., Kannapolis and Univ. of North Carolina at
Chapel Hill.
D190 II678.16 Bone Mass Status Is Associated with
Consumption of Dairy Foods and Fruits and Vegetables in
Young Adult Uruguayan Women. R. Cornes, A. Peña, C.M.
Donangelo. Sch. of Nutr., Univ. de la República, Uruguay.
D191 I678.17 Mouse Model of Muscle Atrophy with
Water-Immersion Restraint Stress. S. Fushimi, T. Nohno, S-i.
Nishimatsu, N. Katase, K. Terada, Y. Watanabe, Y. Ota, M.
Katsuyama, K. Saijoh, H. Katsuyama. Kawasaki Med. Sch.
and Kanazawa Univ., Japan.
D192 II678.18
Butyrate Influences Myogenic Potential
of Porcine Satellite Cells. R.L. Murray, C.H. Stahl. Univ. of
Maryland College Park.
D193 I678.19 Higher Intake of Meat, Oil, Grains,
Fruits and Legumes Discriminated Higher Muscle Mass among
Urban Community - Free Living Adults. C. Bernardino, G.N.
Vilches, L.E.F. Pereira, H.T. Kano, R.C. Burini. Botucatu Med.
Sch., Brazil.
D194 II678.20 Nutraceutical Strategy for Muscle
Maintenance and Recovery. A. Torrent, E. Montell, J. Vergés,
C. Gómez-Cabrera, J. Viña. Bioberica SA, Parafolls and Fac.
of Med., Univ. of Valencia.
D195 I678.21 Effect of Moringa oleifera on Bone
Density in Post-menopausal Women. J. Brown, E. Merritt,
C.N. Mowa, S. McAnulty. Appalachian State Univ.
SUNDAYNUTRITION
D196 II678.22 Daily Consumption of Strawberries
for Eight Weeks Increases Serum Levels of IGF-1 in
Postmenopausal Women. R.G. Feresin, S.A. Johnson, S.
Pourafshar, M.L. Elam, N. Navaei, N. Akhavan, A. Figueroa,
G. Tenenbaum, K. Brummel-Smith, B.H. Arjmandi. Univ. of
Arkansas for Med. Sci., Florida State Univ., Colorado State
Univ. and California State Polytech Univ., Pomona.
D197 I678.23 Skeletal Muscle Mass Characteristics
and Elevated Non-communicable Diseases in Saudi Adults.
E. Combet, M. Alkhalaf, M.E.J. Lean, C. Edwards. Univ.
of Glasgow.
D198 II678.24 Serum
Bone-Building
Metabolites
Are Enhanced by a Restricted Vitamin A Intervention in
Zambian Children with High Liver Reserves of Vitamin A. K.E.
Olsen, N. Binkley, B.M. Gannon, S.A. Tanumihardjo. Univ.
679. NUTRITION ACROSS THE LIFESPAN:
NUTRITION, NEUROBIOLOGY, MOOD
AND BEHAVIOR
Poster
(Cosponsored by: Obesity RIS and Nutrition
Translation RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D199 I679.1
From Visceral Fat to Brain Function:
The Selectively Negative Influence of Central Adiposity on
Neuroelectric Indices in Preadolescent Children. L. Raine,
N. Cohen, A. Kramer, C. Hillman, N. Khan. Univ. of Illinois
Urbana Champaign.
D200 II679.2
Carbohydrates Differentially Influence
Children’s Efficiency during Cognitive Control Tasks. L. Raine,
N. Cohen, A. Kramer, C. Hillman, N. Khan. Univ. of Illinois
Urbana Champaign.
D201 I679.3 Choline Supplementation Improves
Behavioral Aspects of Mice Exposed to Ethanol In Utero. E.
Pjetri, N. Surzenko, C.A. Munson, S.H. Zeisel. Univ. of North
Carolina at Chapel Hill, Kannapolis.
D202 II679.4 Anthocyanin-Rich
Blueberry
Diets
Enhance Protection of Critical Brain Regions Exposed to Acute
Levels of 56Fe Cosmic Radiation. S.M. Poulose, M.E. Kelly,
D.F. Bielinski, M.G. Miller, B. Rabin, B. Shukitt-Hale. USDA
at Tufts Univ. and Univ. of Maryland Baltimore County.
D203 I679.5
Omega-3 Dietary Fatty Acids Improve
Spatial Learning and Memory but Do Not Alter the Escalation
of Alcohol Drinking. L.O. Byerley, J.E. Reppel, A.R. Pahng,
S.R. Edwards. LSU Hlth. Sci. Ctr., New Orleans.
D204 II679.6
Evaluation of Dietary Nutrients on
Clinical Outcomes in Subjects with Chronic-Progressive
Multiple Sclerosis. R.E. Grossmann, E. Perkhounkova, B.
Bisht, T. Wahls. Univ. of Iowa and VA Med. Ctr.
D205 I679.7 Anti-diabetic Efficacy of a Novel
Fenugreek Seed (Trigonella foenum-graecum, Fenfuro) Extract
in Patients with Type-2 Diabetes. D. Bagchi, A. Swaroop,
H.G. Preuss, M. Bagchi, P. Kumar. Univ. of Houston Col. of
Pharm., Cepham Res. Ctr., Piscataway, Georgetown Univ.
Med. Ctr., Dr. Herbs LLC, Concord, CA and Chem. Resources,
Haryana, India.
D206 II679.8
The Association of Dietary Glycine and
Glutamate with ADHD. K.F. Holton, J. Johnstone, J.T. Nigg.
American Univ. and Oregon Hlth. & Sci. Univ.
D207 I679.9
Low Intake of Choline during Pregnancy
Leads to Aberrant Retinal Architecture and Poor Visual
Function in the Offspring. N. Surzenko, I. Trujillo-González,
S.H. Zeisel. Univ. of North Carolina at Chapel Hill, Kannapolis
and UNC Gillings Sch. of Global Publ. Hlth.
D208 II679.10
Protein Intake and Mood: A Systematic
Review. P. Pribis. Univ. of New Mexico.
D209 I679.11 The Impact of Mastication on
Cognition: Evidence for Intervention and the Role of Adult
Hippocampal Neurogenesis. S. Miquel-Kergoat. Wrigley
(Mars Inc.), Chicago.
D210 II679.12 Changes in Nutrient Intakes by Age
among U.S. Adults: Estimates from What We Eat in America,
National Health and Nutrition Examination Survey 2009-2012
S. Mishra, J.D. Goldman, N.R. Sahyoun, A.J. Moshfegh.
Univ. of Maryland College Park and USDA, Beltsville, MD.
D211 I679.13 Effects of Iron Levels and Cerebral
Oxygenation on Free and Cued Recall in Elders with Mild
Cognitive Impairment. M.J. Wenger, B.W. Carlson, L.A. De
Stefano, K.K. Butler, K.A. Curran, S.K. Daji, E.H. Mooney,
L.A. Herhsey, J.R. Carlson. Univ. of Oklahoma and Univ. of
Oklahoma Hlth. Sci. Ctr.
D212 II679.14 Chocolate and the Brain: Cacao
Increases power Spectral Density (µV2) of EEG Gamma Wave
Band Activity (31-40Hz) Which Is Associated with Neuronal
Synchronization, Enhanced Cognition, Memory, Recall and
Physiological Benefits. L. Berk, J. Lee, D. Mali, E. Lohman,
G. Bains, N. Daher, J. Bradburn, R. Mohite, N. Vijayan, S.
Juneja, S. Shah, A. Shah, P. Shah. Loma Linda Univ.
D213 I679.15 Low versus High Cacao Anti-oxidant
Consumption Effects on Power Spectral Density (µV2) EEG
Brain Frequencies (0-40Hz) and Significance of Sensory
Olfaction and Taste Deprivation of Cacao to Decrease the
Response of Power Spectral Density for Gamma Frequency.
L. Berk, J. Lee, D. Mali, E. Lohman, G. Bains, N. Daher, J.
Bradburn, R. Mohite, S. Juneja, N. Vijayan, S. Shah, A. Shah,
P. Shah. Loma Linda Univ.
D214 II679.16 Fructose
Extends
Lifespan
and
Reduces Intestinal Fat Deposition in Caenorhabditis elegans
M. Wang, R.A. Laine, C. Gao, P. Tran, N. Mai, J.W. Finley, S.B.
Heymsfield, F.L. Greenway, Z. Li, D. Heber, J.H. Burton, W.D.
Johnson, J. Zheng. Sch. of Nutr. and Food Sci., LSU AgCtr.,
Pennington Biomed. Res. Ctr. and A&M Col. and UCLA.
D215 I679.17 Relationship between Self-Reported
Polyphenol and, Caffeine Consumption and Mood. A. Boolani,
J. TeRiele, C. Towler, T. Baghurst. Clarkson Univ. and
Oklahoma State Univ.
D216 II679.18
Dietary Strawberry Improves Cognition
in Older Adults: A Randomized, Double-Blind, PlaceboControlled Trial. M.G. Miller, N. Thangthaeng, T.M. Scott, B.
Shukitt-Hale. USDA and Tufts Univ., Boston.
203
S
U
N
NUTRITIONSUNDAY
D217 I679.19 The Relationship between Folic Acid,
Vitamin B12, and Vitamin B6 Intakes and Depression in Women
Who Use Hormonal Oral Contraceptives: 2003-2008 National
Health and Nutrition Examination Survey. S. Zolfaghari, L.
Wang, V. Gray, R. Roy. California State Univ., Long Beach.
D218 II679.20 Dietary Plant Lectins Affect Lifespan
and Dopaminergic Neurons in Ceanorhabditis elegans Model
Organism. M. Wang, R.A. Laine, J.N. Keller, F.L. Greenway,
S.B. Heymsfield, J. Zheng. Sch. of Nutr. and Food Sci., A&M
Col. and Pennington Biomed. Res. Ctr., LSU, Baton Rouge.
680. NUTRITION TRANSLATION: FOOD SCIENCE
AND TECHNOLOGY IN NUTRITION
Poster
(Sponsored by: Nutrition Translation RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D219 I680.1
Quinoa Ancient Whole Grain GlutenFree Snacks. T.S. Kahlon, R.J. Avena_Bustillos, M-C.M.
Chiu. USDA, Albany, CA.
D220 II680.2 Ancient Whole Grain Gluten-Free
Buckwheat Snacks. T.S. Kahlon, R.J. Avena_Bustillos,
M-C.M. Chiu. USDA, Albany, CA.
D221 I680.3
Effect of Different Cooking Methods on
Vitamin Contents and True Retention in Selected Vegetables.
J. Lee, J. Yang, Y. Choi, K. Lee. Chungbuk Natl. Univ. and Natl.
Acad. of Agr. Sci, RDA, Jeonju, South Korea.
D222 II680.4
Effects of High Pressure Treatment and
EDTA-2Na on Lipid Oxidation and Color Properties of Altay
Sheep Body Fat. Q. Wang, C. Liu. Chongqing Univ. of Educ.
and Xin Jiang Acad. of Agr. and Reclamation Sci., China.
D223 I680.5
Characterization of Anthocyanins in
Sweet Potato Shoots. X. Su, J. Griffin, B. Katz, J. Tomich, W.
Wang. Kansas State Univ.
D224 II680.6 Ultrasound-Induced
Changes
in
Structural and Physical Properties of Whey Proteins. M. Guo,
X. Shen, S. Shao. Jilin Univ., China and Univ. of Vermont.
D225 I680.7
Speciation and Monitoring of Inorganic
Arsenic in Rice by HPLC-ICP/MS. S.G. Lee, S-H. Chun, D.H.
Kim, Y.S. Lee, K-W. Lee. Col. of Life Sci. and Biotechnol.,
Korea Univ.
D226 II680.8 Analysis
of
Polycyclic Aromatic
Hydrocarbons for Reduction in Simple-Processed Foods
According to Manufacturing System. S-J. Kang, S-Y. Yang,
K-W. Lee. Col. of Life Sci. and Biotechnol., Korea Univ.
D227 I680.9
Development of Novel Hollow Zein
Nanoparticles for Delivery of Nutraceuticals. S. Hu, M-L.
Fernandez, Y. Luo. Univ. of Connecticut.
681. NUTRITION TRANSLATION: NUTRITION
SCIENCE FOR PUBLIC POLICY, PRACTICE AND
THE CONSUMER
Poster
(Sponsored by: Nutrition Translation RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D228 II681.1
Federal Policy Development Process
for the 2015-2020 Dietary Guidelines for Americans. K.O.
Casavale, E. Essery Stoody, C. Rihane, R. Olson. HHS,
Rockville, MD and USDA, Alexandria, VA.
D229 I681.2 The Science Behind the Dietary
Guidelines for Americans E.E. Stoody, K. Casavale, C. Rihane,
R. Olson. USDA, Alexandria, VA and HHS, Rockville, MD.
D230 II681.3
Marketing Strategies of the Industry of
Sugar-Sweetened Beverages: Monitoring of In-Store Special
Offers. A. Velasco, I.P. Hernandez, P. Aguilar. Natl. Publ. Hlth.
Inst., Cuernavaca.
D231 I681.4
Prevalence and Patterns of Wild Berry
Consumption among Park Users in Western Washington. E.G.
Diehl, A. Kazaks. Bastyr Univ., WA.
D232 II681.5
Intakes of Processed Meat and Red
Meat in Koreans Are Far Below the Level Referred to Increase
the Risk of Colorectal Cancer by IARC. J.Y. Lee, M. Yon, D.
Kim, J. Nam, S. Park, H-S. Lee, C-i. Kim. Korea Hlth. Industry
Develop. Inst., Cheongju.
D233 I681.6
Comparison of an Egg White versus
Toaster Pastry Breakfast on Dietary Intake and Quality in
College-Age Women. J. Eckerson, N. Allen, A. Lieb, K.
Mullen. Creighton Univ.
D234 II681.7
Improving the Food Supply by Product
Reformulation: Using Nutrient Profiling to Evaluate Foods
Consumed in the USA. F. Mölenberg, A. Vlassopoulos, G.
Masset, U. Lehmann. Wageningen Univ., Netherlands and
Nestle Res. Ctr., Lausanne.
D235 I681.8 Discrepancies
between
Health
Professionals’ Understanding and the Evidence for Sugars
Related Nutrition Issues in Canada. F. Wang, C.L. DiAngelo,
L. Pasut, S.L. Marsden. Nutr. Info. Svc., Canadian Sugar
Inst., Toronto.
682. MEDICAL NUTRITION: APPLIED PHYSIOLOGY,
NUTRITION, AND METABOLISM
Poster
(Sponsored by: Medical Nutrition Council)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D236 II682.1
Ingesting 25 g/Day Milled Chia Seeds
for Two Weeks Does Not Affect Exercise Performance. D.
Nieman, M.P. Meaney. Appalachian State Univ., North Carolina
Res. Campus, Kannapolis.
204
SUNDAYNUTRITION
D237 I682.2 Metabolomics-Based
Analysis
of
Banana and Pear Ingestion on Exercise Performance and
Recovery. D. Nieman, N. Gillitt, W. Sha, M.P. Meaney, C.
John, K. Pappan, J. Kinchen. Appalachian State Univ., North
Carolina Res. Campus, Dole Nutr. Inst. and Univ. of North
Carolina at Charlotte, Kannapolis and Metabolon, Durham, NC.
D238 II682.3
The Effects of Resistance Training with
L-Carnitine Supplementation on Total Antioxidant Capacity
and Lipid Peroxidation in Untrained Men. M. Koozehchian, E.
Falah, A. Daneshfar, M. Kaveh, B.K. Sanchez, G. Owlia, A.
Moosakhani, G. Nazem, N. Moradi, R.B. Kreider. Texas A&M
Univ., Tarbiat Modares Univ., Iran, Karnataka Col. of Pharm.,
Bangalore, Texas Southern Univ., Univ. of Tehran and Azad
Univ., Iran.
D239 I682.4 Cross-Validation
of
Recent
and
Longstanding Resting Metabolic Rate Prediction Equations.
K.D. Flack, W.A. Siders, L. Johnson, J.N. Roemmich. USDA,
Grand Forks.
D240 II682.5
Korean Fermented Soy Sauce Modulate
Na+/K+-ATPase Activity in HK-2 Cells. Y-S. Cha, E-G. Mun, M.
Kim, J-s. Yook. Chonbuk Natl. Univ., South Korea.
D241 I682.6 Bitter
Receptors
and
Glucose
Transporters Interact to Control Carbohydrate and Immune
Responses in the Gut. K.M. Palatini, P-J. Durand, T.
Rathinasabapathy, D. Esposito, S. Komarnytsky. North
Carolina State Univ., Kannapolis and Raleigh, Agrosup Dijon,
France and Intl. Med. Univ., Juala Lumpur.
D242 II682.7
Monitoring Clinical Characteristics and
Lifestyle Factors to Reduce Confounding in Studies of Peripheral
Vascular Function. Y. Liu, A.D. Fly, J. Risting, Z. Wang, J.E.
Klaunig. Sch. of Publ. Hlth., Indiana Univ. Bloomington.
D243 I682.8
Post-prandial Exhaled 8-Isoprostane
Responses to Meals of Varying Caloric and Fat Content in Nonasthmatic, Insufficiently Active Men. S.P. Kurti, S.R. Emerson,
S.K. Rosenkranz, C.S. Teeman, E.M. Emerson, B.J. Cull,
J.R. Smith, C.A. Harms. Kansas State Univ.
D245 I682.10 Metabolomics Analysis of Serum and
Urine after Bean Consumption by Patients with Peripheral
Arterial Disease. L. Wang, P. Zahradka, C. Taylor, M. Aliani.
Univ. of Manitoba and St. Boniface Res. Ctr., Winnipeg.
D246 II682.11 Unique Post-prandial Amino Acid
Responses following Oral Administration of Serum-Derived
Bovine Immunoglobulin. E.M. Weaver, B.W. Petschow, D.W.
Mathews, B. Burnett, A.L. Shaw, T.P. Bradshaw, J. Hinkle.
Entera Hlth. Inc., IA and NC and EarlyPhase Sci. Inc., NC.
D247 I682.12 The Perceived Impact of Moving to
United States on Eating Habits among College Students from
Countries Gulf Cooperation Council. M. Huwaikem, A. Campa.
Florida Intl. Univ.
D248 II682.13 Foodomics Database: A New Tool for
Precision Medicine and the -omic Toolbox. H.J. Allen, D.J.
Lennon, J. Lukosaityte, P.R. Borum. Univ. of Florida.
D249 I682.14 A Randomized Controlled Trial of
a Gluten-Free Weight Loss Diet in HLA DQ2 or D8 Positive
Subjects. M. Vranceanu, D. de Lorenzo, K. Grimaldi.
Estetica Milano Sei, Univ. Pompeu Fabra, Barcelona and
Eurogenetica, London.
D250 II682.15 The Impact of Online Dietary
Assessment to Efficiency of Nutrition Counseling: A Pilot. R.P.
Watowicz, R.K. Wexler, R. Weiss, C.K. Spees, C.A. Taylor.
The Ohio State Univ., Viocare Inc., Princeton.
D251 I682.16 Severely
Compromised
Anabolic
Response to Nutrition in a Pseudomonas aeroginosa-Induced
Hyper-dynamic Sepsis-Recovery Pig Model. G.A. Ten Have,
M.P. Engelen, R.R. Wolfe, N.E. Deutz. Texas A&M Univ. and
Univ. of Arkansas for Med. Sci.
683. MEDICAL NUTRITION: NUTRITION AND
GASTROINTESTINAL FUNCTION – THE
MICROBIOME AND BEYOND
Poster
(Sponsored by: Medical Nutrition Council)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D252 II683.1 Gut
Microbiota
in
Wild
Type
Caenorhabditis elegans: Stimulation by Media Containing
Dietary Fiber from Prowashonupana Barley. J. Zheng, C. Gao,
A.M. Raggio, F.M. Enright, R.J. Martin, M.E. Janes, F.L.
Greenway, M.J. Keenan. PBRC and Sch. of Nutr. and Food
Sci., LSU, Baton Rouge and Univ. of California, Davis.
D253 I683.2
Fiber Utilizing Capacity Varies with
Prevotella versus Bacteroides Enterotypes. T. Chen, W. Long,
C. Zhang, S. Liu, L. Zhao, B. Hamaker. Purdue Univ. and
Shanghai Jiao Tong Univ., China.
D254 II683.3
Food-Grade Antimicrobial ε-Polylysine
Transiently Perturbs the Structure of the Murine Gut
Microbiome. X. You, J. Einson, C. Lopez-Peña, M. Song, H.
Xiao, D.J. McClements, D.A. Sela. Univ. of Massachusetts
Amherst and Univ. of Massachusetts Med. Sch.
D255 I683.4 Modulation of Colonic Microbiota
Populations by Polyphenolic Containing Sorghum Brans May
Protect against Development of Metabolic Disease. S.K. Lloyd,
L.E. Ritchie, K.K. Hicks, M.A. Azcarate-Peril, N.D. Turner.
Texas A&M Univ. and Univ. of North Carolina Sch. of Med.
D256 II683.5Prebiotic
Short-Chain
Fructooligosaccharides Increases Abundance of the
Butyrate Producing Microbial Community Differentially When
Administered with or without Probiotic Lactobacillus rhamnosus
GG in Piglets with Short-Bowel Syndrome. B.R. Loman, K.A.
Tappenden. Univ. of Illinois at Urbana-Champaign.
D257 I683.6 Metatranscriptomics: Monitoring Gut
Microbiome Activity in Response to Diet. S.T. Westreich, I.
Korf, D.A. Mills, D.G. Lemay. Univ. of California, Davis.
D258 II683.7
Substrate Structure-Dependent Growth
of Bacteroides xylanisolvens XB1A on Corn Arabinoxylan
Fragments in Pure and Mixed Culture Environments. X. Nie,
E. Martens, Y. Xiao, B. Reuhs, B. Hamaker. Purdue Univ. and
Univ. of Michigan Med. Sch.
D259 I683.8
The Effects of Symbiotic Ice Cream on
Gastrointestinal Symptoms and Microbiome. E. McNamara, D.
Giraud, S. Fernando, J. Albrecht. Univ. of Nebraska.
D260 II683.9 Effects of Quinoa (Chenopodium
quinoa) Consumption on Fecal Microbiome of Obese Diabetic
(db/db) Mice. G. Noratto, J. Garcia-Mazcorro, D. Mills.
Washington State Univ., Texas A&M Univ., Autonomous Univ.
of Nuevo León, Mexico and Univ. of California, Davis.
205
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D261 I683.10 Pectin Feeding for 16 Weeks
Improves Learning and Memory in Young C57BL/6_J Mice:
A Relationship to the Gut Microbiota? L. Mailing, J. Allen,
T-W. Liu, T. Bhattacharya, P. Park, B. Pence, J. Rodney, G.
Fahey, K. Swanson, J. Rhodes, J. Woods. Univ. of Illinois
D262 II683.11
Decreased Abundance of Firmicutes in
the Gut Microbiota after Consumption of a Diet Containing Milk
Fats. H. Walsh, H. Haq, L. Cersosimo, C.L. Kien, J. Kraft.
Univ. of Vermont.
684. ENERGY AND MACRONUTRIENT METABOLISM:
LIPID AND FATTY ACID METABOLISM
AND TRANSPORT
Poster
(Sponsored by: Energy & Macronutrient Metabolism RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D263 I684.1
Consuming 1 Egg Per Day Favorably
Alters Diastolic Blood Pressure and Plasma Lipid Profiles in a
Young, Healthy Population. D.M. DiMarco, A.M. Missimer, A.G.
Murillo, B.S.O. Lemos, M.L. Fernandez. Univ. of Connecticut.
D264 II684.2 Diet-Induced Activation of PPARΔ
Improves Liver Metabolic Profiles in Mice. C.M. Paton, R.A.
Vaughan, E. Alpergin, F. Assadi-Porter, M.K. Dowd. Univ.
of Georgia, High Point Univ., Univ. of Wisconsin-Madison and
USDA, New Orleans.
D265 I684.3
Bioavailability of Long Chain Omega-3
Polyunsaturated Fatty Acids from Phospholipid-Rich Herring
Roe Oil in Men and Women with Mildly Elevated Triacylglycerols.
C.M. Cook, H. Hallaråker, P.C. Sæbø, S.M. Innis, K.M. Kelley,
K.D. Sanoshy, A. Berger, K.C. Maki. Biofortis Clin. Res.,
Addison, IL, Arctic Nutr. AS, Ørsta, Norway, Univ. of British
Columbia and British Columbia Children’s Hosp.
D266 II684.4
MiR-383 Is Associated with Ameliorated
Hepatic Steatosis in Mice Fed on High-Fat Diet. B. Yan, X.
Duan, Y. Shi, G. Le. Jiangnan Univ., China.
D267 I684.5
Absorption of Eicosapentaenoic Acid
and Docosahexaenoic Acid in Wax-Ester Rich Oil from the
Marine Crustacean, Calanus finmarchicus, in Healthy Men and
Women. C.M. Cook, T. Larsen, H.J. Kern, L.D. Derrig, K.M.
Kelley, K.S. Tande. Biofortis Clin. Res., Addison, IL, Fac, of
Hlth. Sci., Univ. of Tromsø and Calanus AS, Tromsø, Norway.
D268 II684.6
Korean Pine Nut Oil Replacement
Decreases Intestinal Lipid Uptake While Improves Hepatic
Lipid Metabolism in High-Fat Diet Fed Mice. Z. Shuang, S.
Park, Y. Lim, S. Shin, S.N. Han. Seoul Natl. Univ.
D269 I684.7
Obesogenic Diets Enriched in Oleic
Acid versus Saturated Fatty Acids Differentially Modify
Polyunsaturated Fatty Acid Composition in Liver and Visceral
Adipose. M. Picklo, E. Murphy. USDA, Grand Forks and Univ.
of North Dakota.
D270 II684.8
Mouse Carnitine Palmitoyltransferase 2
Is Required to Sustain Cardiac Function. J.M. Ellis, L.Y. Hasek,
E.J. Yurovich, K.L. Harris, C.J. Goergen. Purdue Univ.
206
D271 I684.9
Retroconversion of Docosahexaenoic
Acid (22:6n-3) to Eicosapentaenoic Acid (20:5n-3) Dominates
over Elongation to 24:6n-3 in Human Cells. H.K. Park, P.
Lawrence, K.S.D. Kothapalli, J.T. Brenna. Cornell Univ.
D272 II684.10
Characterization of the Human EA.hy926
Endothelial Cell Response to Dietary Polyunsaturated Fatty
Acids as a Function of Growth Conditions. Y. Du, C. Taylor, H.
Aukema, P. Zahradka. Univ. of Manitoba and Canadian Ctr. for
Agri-Food Res. in Hlth. and Med., Winnipeg.
D273 I684.11 Comparison of Preparative High
Density Lipoprotein Separation Methods for Subsequent Omic
Analysis. C. Zhu, R. Sacchi, C. Rhodes, B. Tan, J.K. Muchena,
C.B. Lebrilla, A.M. Zivkovic. Univ. of California, Davis.
D274 II684.12 RNA Sequencing: A Novel FADS2
Isoform Identified in Milk Fat Globule Suppresses FADS2Mediated Delta 6-Desaturation of Omega-3 Fatty Acids.
K.S.D. Kothapalli, H.G. Park, X. Guo, X. Sun, J. Zou, S.S.
Hyon, X. Qin, P. Lawrence, R.R. Ran-Ressler, J.Y. Zhang, Z.
Gu, J.T. Brenna. Cornell Univ., Jilin Univ., China and Nestlé,
Minnetonka, MN.
D275 I684.13 Functional Characterization Reveals
Human ELOVL3 Role in the Biosynthesis of iso-20:0 Z. Wang,
H.G. Park, P. Lawrence, K.S.D. Kothapalli, J.T. Brenna.
Cornell Univ.
D276 II684.14 Functional Characterization of Novel
Fads3 Isoform. J.Y. Zhang, X. Qin, H.G. Park, E. Kim, G. Liu,
K.S.D. Kothapalli, J.T. Brenna. Cornell Univ. and Col. of Vet.
Med., Jilin Univ., China.
D277 I684.15 Associations between Plasma Fatty
Acid Composition, Estimated Desaturase Indices, and
Measures of Insulin Resistance in 4th- and 5th-Grade
Children. L.M. Nguyen, J.W. Newman, A.G. Borkowska, S.
Zidenberg-Cherr, M. Dharmar, I.J. Gray, J.D. Linnell, H.M.
Young, R.E. Scherr. Univ. of California, Davis, USDA, Davis,
Penn State and Sch. of Nursing, Univ. of California Davis Hlth.
Syst., Sacramento.
D278 II684.16 Size and Timing Matter: Differential
Triglyceride Responses to Three Meal Conditions. S.R.
Emerson, S.P. Kurti, C.S. Teeman, E.M. Emerson, B.J. Cull,
M.D. Haub, S.K. Rosenkranz. Kansas State Univ.
D279 I684.17 Metabolic Profiling and Quantification
of Ceramide by Liquid Chromatography Mass Spectrometry.
Y. Chen, D. McLaren, J. Liu, W. Yin, R. Mayoral, A. Petrov, L.
Bojic, O. Berejnaia, S. Previs, D. Kelley. Merck, Kenilworth, NJ.
D280 II684.18
Quantifying Fatty Acid Synthesis Using
Heavy Water: Enabling Back-to-Back Studies. S. Previs, K.
Herath, A. Nawrocki, S. Singh, L. Kang, M. Erion, D. Kelley.
Merck, Kenilworth, NJ.
D281 I684.19
Exogenous Oxidation of Lipids Reduces
the Deleterious Effects of a High Fat Diet Composed of These
Lipids in a Swine Model of Familial Hypercholesterolemia and
Spontaneous Atherosclerosis. F. Arowolo, J.J. Meudt, C.
Cabelka, D.T. Schomberg, N.J. Chesmore, A. Escobar López,
S.T. Trace, J.L. Reichert, T.D. Crenshaw, M.P. Richards, D.
Shanmuganayagam. Univ. of Wisconsin-Madison.
D282 II684.20
The Variant R230C Is Associated to a
Higher Risk for Hypoalphalipoproteinemia, in School-Aged
Mexicans of Hidalgo, Mexico. A. Gutierrez Gamo, E.M.
Tejero Barrera, M. Galván García, E. Gamez-Valdez, J.C.
Fernández, A.V. Contreras, G. López Rodríguez. Univ.
Iberoamericana and INMEGEN, Mexico City and Autonom.
Univ. of Hidalgo State (UAEH), Mexico.
SUNDAYNUTRITION
EMM AND THE GUT
686. OBESITY: BODY COMPOSITION
Poster
Poster
(Sponsored by: Obesity RIS)
Exhibit Halls A-D
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D283 I685.1
Increased Gastrointestinal Permeability
during Prolonged Physical Stress Is Associated with Lower
Energy Intakes but Not Dietary Macronutrient Composition. J.P.
Karl, L.M. Margolis, N.E. Murphy, S. Martini, Y. Gundersen,
J.W. Castellani, C.T. Carrigan, H.K. Teien, E.H. Madslien, S.J.
Montain, S.M. Pasiakos. U.S. Army Res. Inst. of Envrn. Med.,
Natick, MA and Defense Res. Establishment, Kjeller, Norway.
D284 II685.2
Dairy Milk Components Differentially
Affect Gastrointestinal Health Markers in C57Bl/6 Mice.
T.R. Price, S.A. Baskaran, K. Moncada, Y. Minamoto, C.
Klemashevich, A. Jayaraman, J.S. Suchodolski, R.L.
Walzem. Texas A&M Univ.
D285 I685.3GC-TOF/MS-Based
Metabolomic
Profiling of Goto-Kakizaki Rats: Comparison of Diets Enriched
with Purified Resistant Starch or Resistant Starch in the Form
of Whole-Grain Flour. R.J. Martin, J. Fahrmann, D. CarvajalAldaz, J. Guice, R. Page, A. Raggio, D. Coulon, R. Stout, C.
Pelkman, M.L. Marco, M.J. Keenan. Univ. of California, Davis,
MD Anderson, Houston, LSU AgCtr, LSU A&M and Ingredion
Inc., Bridgewater, NJ.
D286 II685.4 Protein and Glutathione Kinetics
in Protein Deficient Piglets with Colitis in Response to
Nutritional Interventions: Protein Repletion or N-Acetylcysteine
Supplementation. M. Hong, J.Y. Xiao, E. Nitschmann, L.J.
Wykes. Sch. of Dietetics and Human Nutr., McGill Univ.
D287 I685.5 The Effect of Fructose-Containing
Sugars on Glycemic Control: A Systematic Review and
Meta-analysis of Controlled Trials. V.L. Choo, A.I. Cozma,
E. Viguiliouk, S. Blanco Mejia, C.W.C. Kendall, R.J. de
Souza, D.J.A. Jenkins, J.L. Sievenpiper. Univ. of Toronto, St.
Michael’s Hosp., Toronto and McMaster Univ., Canada.
D288 II685.6
Metabolic Profiling Reveals Differences
in Plasma Concentrations of Arabinose and Xylose after
Consumption of Fiber-Rich Pasta and Wheat Bread with a
Differential Rate of Systemic Appearance of Starch-Derived
Glucose in Healthy Men. A. Pantophlet, C. Eelderink, R.
Vonk, S. Wopereis, A. Dijk-Stroeve, S. Bijlsma, L. Stee Van,
I. Bobeldijk, M. Priebe. Univ. Med. Ctr. Groningen and TNO,
Zeist, Netherlands.
D289 I685.7
Plasma Bile Acid Responses in Methane
and Non-methane Producers to Standard Breakfast Meals. B.
Rust, M. La Frano, J.W. Newman, K. Agrawal, W. Horn, L.
Welch, M. Marco, R. Martin, N.L. Keim. Univ. of Califormia,
Davis and USDA, Davis.
1:45 pm–2:45 pm (II)
D290 II686.1 Evaluation in Children of Novel
Bluetooth Bioimpedance Analysis Devices Designed for
mHealth Applications. J. Zheng, M. Wang, A. Choi, J.Y-H.
Kim, S.W. Jo, J. Cho, Y.A. Bhagat, I. Kim, S.B. Heymsfield.
PBRC and Sch. of Nutr. and Food Sci., LSU, Samsung
Electronics, Suwon, South Korea and Samsung Res. America,
Richardson, TX.
D291 I686.2 The Effects of Pedometer-Metered
Walking on Body Composition, Blood Glucose, Diet Alterations,
Blood Pressure, and Waist-to-Hip Ratios in College-Aged
Participants: A Pilot Study. L. Meeks, A. Reynaga, C. Worland,
B. Burns-Whitmore. Cal Poly Univ., Pomona.
D292 II686.3
The Gender Differences in the Change
of Dietary Intake and Body Composition following the First
Semester for Undergraduate First Year Students at a Small
Liberal Arts University. J. Nunez, D. Vera, S.L. Dunn. Univ. of
La Verne.
D293 I686.4 Differences in Body Composition
According to Gender in Schoolchildren in Arandas, Mexico. E.
Romero-Velarde, E.A. Caro-Sabido, E.M. Vasquez-Garibay,
A. Larrosa-Haro. Univ. de Guadalajara and Hosp. Civil de
Guadalajara Dr. Juan I. Menchaca.
D294 II686.5
Effects of Endurance and Strength
Training and Their Combined Intervention on Body Composition
of High School Students. J. He, D. Cui, Y. Sun. East China
Normal Univ.
D295 I686.6
Anthropometric Measurements Differ
among Overweight and Obese Adults of Varying Socioeconomic
Status but No Differences in Fruit and Vegetable Intake. Y.
Rhee, K. Honrath, M.G. Wagner. North Dakota State Univ. and
Concordia Col., MN.
D296 II686.7 Long-Term Vitamin D Deficiency
Decreases Bodyweight and Adipose Tissue Mass in Female
Mice. A.M. Belenchia, C. Rosenfeld, S.A. Johnson, A.
Kieschnick, C. Peterson. Univ. of Missouri-Columbia.
D297 I686.8
Comparison of MRI and DXA for
Measurement of Visceral Adipose Tissue in Adolescent
Females. S.L. Belcher, J.M. Kindler, N.K. Pollock, H.L. Ross,
C.M. Modlesky, E.M. Laing, R.D. Lewis. Univ. of Georgia, Med.
Col. of Georgia-Georgia Regents Univ. and Univ. of Delaware.
D298 II686.9
Changes in Body Composition Despite
Changes in Dietary Intake or Eating Behaviors during the Fall
Semester in First Year College Students. K. Jones, D. Vera,
S.L. Dunn. Univ. of La Verne.
D299 I686.10 Fat Weight Rises with Increased
Severity of Obesity in Women but Not Lean Body Mass. T.G.
Babb, V. Bernhardt, D. Bhammar, J. Stickford, J.T. Basset,
R. Marines-Price, M. Roman. Texas Hlth. Presbyterian
& Univ. of Texas Southwestern Med. Ctr. and Texas
A&M Univ.-Commerce.
207
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NUTRITIONSUNDAY
D300 II686.11
Sex Differences of Body fat Distribution
in Mexican Adolescents 10-14 Years Old with Type 2 Diabetes
Mellitus Risk Factors. A. Soto-Piña, A. Esquivel-Roque, C.
Flores-Reséndiz, A.C. Fernández-Gaxiola, P. TlatempaSotelo. Autonomous Univ. of State of Mexico, Toluca.
D301 I686.12 Assessment of Visceral Adipose
Tissue by Dual Energy X-Ray Absorptiometry and Magnetic
Resonance Imaging among a Young Adult Obese Population.
C.L. Carpenter, M. Sarma, R. Nagarajan, C.C. Lee, M.A.
Thomas, V.L. Go, T.J. Hahn. UCLA.
687. OBESITY: CHILDHOOD OBESITY
MANAGEMENT
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D302 II687.1
Associations between Weight-Related
Variables, Gender, and Age in Overweight and Obese
Preadolescents and Adolescents. E.L. Delavan, T. Crook, J.
Phelps, R. Hakkak. Univ. of Arkansas for Med. Sci.
D303 I687.2
Energy Expenditure in Children with
Prader-Willi Syndrome during Walking. F.A. Chavoya, A.
Slowetzky-Amaro, D. Castner, A. Hyde, J. Ramirez, A. Wong,
V. Layvant, D. Rubin. California State Univ., Fullerton.
D304 II687.3
Defining Infant Rapid Weight Gain to
Best Predict Subsequent Obesity. C.L. Eckhardt, M.C. Leo,
N. Karanja. Sch. of Community Hlth., Portland State Univ. and
Kaiser Permanente Ctr. for Hlth. Res., Portland.
D305 I687.4
Healthy as a Horse. H. Battisti, F.
Battisti. Marywood Univ., PA, Endwell Family Physicians, NY
and SUNY Broome Community Col., Binghamton.
D306 II687.5
Respiratory Effects of Weight Loss or
Gain Over 1 Year in Obese Children. D.M. Bhammar, J.L.
Stickford, R.J. Kim, R. Marines-Price, J.T. Bassett, M.C.
Roman, A. Kruetzer, T.G. Babb. Valdosta State Univ., Dallas
Inst. for Exercise and Envrn. Med., Appalachian State Univ.
and Univ. of Texas Southwestern Med. Ctr.
D307 I687.6
Effects of Apple Snacking on Body
Weight Status and Metabolic Profiles of Overweight and Obese
Children. C. Cabalbag, D. Metti, A. Tunstall, L. Almaiman,
M.Y. Hong, M. Kern, S. Hooshmand. San Diego State Univ.
688. DIET AND CANCER: MOLECULAR TARGETS
Poster
(Sponsored by: Diet and Cancer RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D308 II688.1
Curcumin Inhibits Lymphangiogenesis
In Vitro and In Vivo through Suppressing VEGF Receptor
Signaling. W. Wang. Univ. of Massachusetts Amherst.
208
D309 I688.2
Synergystic Interaction of Common
Bean (Phaseolus vulgaris L.) Peptides and Oxaliplatin on
Proliferation of HCT116 Colorectal Cancer Cells through
Mitochondrial Depolarization and DNA Damage. D-A. LunaVital, E.G. De Mejia, G. Loarca-Pina. Autonomous Univ. of
Querétaro, Mexico and Univ. of Illinois, Urbana.
D310 II688.3
An Oral Iron Compound That Decreases
Colon Cancer Cell Growth. N.M. Scheers, D.A. Pereira, J.J.
Powell. Chalmers Univ. of Technol., Sweden and MRC Human
Nutr. Res., Cambridge, U.K.
D311 I688.41α,25-Dihydroxyvitamin
D3 Inhibits
De Novo Fatty Acid Synthesis and Metastatic Capability of
Breast Cancer Cells. T. Wilmanski, A. Barnard, S. Donkin, M.
Parikh, K. Buhman, J. Kirshner, J. Burgess, D. Teegarden.
Purdue Univ.
D312 II688.5
DHA Supplementation Alters Cofilin1/
pVASP-S239 Expression, Sub-cellular, Localization, and
Suppresses Migration and Proliferation in Lung Cancer Cells.
M. Ali, K.M. Heyob, L.K. Rogers. Nationwide Children’s Hosp.
and The Ohio State Univ.
D313 I688.6
Characterization of the Pro-inflammatory
Cytokine IL-1β on Butyrate Oxidation in Colorectal Cancer
Cells. M. Johnstone, A. Han, N. Bennett, C. Standifer, A.
Smith, D. Donohoe. Univ. of Tennessee, Knoxville.
D314 II688.7 Pyrogallol, a Microbial Metabolites
from Mango Tannins (Mangifera indica L.) Suppresses Breast
Cancer Ductal Carcinoma In Situ Proliferation in Both In Vitro
and In Vivo. S.U. Mertens-Talcott, H. Kim, R. Barnes, S.T.
Talcott, M. Nemec. Texas A&M Univ.
D315 I688.8
Comparing Gene Expression between
Resveratrol Sensitive and Insensitive Cells Using RNASequencing Methods. C.W. Cranney, J. Kenealey. Brigham
Young Univ.
D316 II688.9
Butyrate Plays Differential Roles in
Cellular Signaling in Cancerous HCT116 and Noncancerous
NCM460 Colon Cells. H. Zeng, D.P. Taussig, W-H. Cheng, R.
Hakkak. USDA, Grand Forks, Mississippi State Univ.,Univ. of
Arkansas for Med. Sci. and Arkansas Children Hosp. Res. Inst.
D317 I688.10 An Inhibitory Role of Piceatannol in
Cancer Cachexia-Associated Lipolysis In Vitro. J. Kershaw,
K-H. Kim. Purdue Univ.
D318 II688.11
Anti-tumor Properties of Beta-Sitosterol
in AGS Human Gastric Adenocarcinoma Cells and Tumor
Xenograft Mice. E. Shin, S.H. Kim, J-T. Hwang. Univ. of Sci. &
Technol., Daejeon and Korea Food Res. Inst., Seongnam.
D319 I688.12 Allicin Inhibits Lymphangiogenesis In
Vitro and in Vivo. W. Wang. Univ. of Massachusetts Amherst.
D320 II688.13 Soybean-Derived Glyceollins Promote
Nrf2-Mediated Detoxifying Enzymes In Colorectal Cells. G. Jo,
J. Oh, S. Kang, M. Kim, J. Jang, G. Jeong, H. Seo, S. Ju,
Y. Woo, S. Lim, J-S. Kim. Sch. of Food Sci. and Biotechnol.,
BK21 Plus Creative Innovation Group, Kyungpook Natl. Univ.
and Hallym Univ., South Korea.
D321 I688.14 Herbs FG Matrix for Advance Wound
Care Therapy for Diabetic, Venous, Artelous Ulcer. F.U. Izunobi,
G.P. Einstein. Col. of Med., Einstein Med. Inst. Corp. USA.
D322 II688.15
Terpenoid-Enriched Loquat Leaf Extract
Controls the Growth and Survival of Pancreatic Cancer Cell
and Acts on Glucose Metabolsim to Alter Pentose Phosphate
Pathway. Q-Y. Lu, J. Yang, V-L. Go, Z. Li, W-N. Lee. UCLA and
LA BioMed, Torrance.
D323 I688.16
Delta Tocotrienal Inhibit mTOR Pathway
by Modulating Glutamine Uptake and Transporters in Nonsmall Cell Lung Cancer. L.D. Rajasinghe. Wayne State Univ.
SUNDAYNUTRITION
D324 II688.17
Apiaceous Vegetable Intake Modulates
Expression of DNA Damage Signaling Pathway Genes and
miRNA in Wistar Rats. J.K. Kim, D.D. Gallaher, S.P. Trudo.
Univ. of Arkansas and Univ. of Minnesota, St. Paul.
689. CARIG: BIOAVAILABILITY AND METABOLISM
OF CAROTENOIDS AND VITAMIN A
Poster
(Sponsored by: CARIG RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D325 I689.1
Antioxidative Activity of (3R,3R′) and
(3S,3S′) Astaxanthin in Caenorhabditis elegans X. Liu, Q. Luo,
Y. Cao, X. Liu, H. Xiao. Col. of Food Sci., South China Agr.
Univ. and Univ. of Massachusettes Amherst.
D326 II689.2
Lutein and DHA Co-localize in Cell
Membranes of Brain Regions Controlling Cognition in the
Rhesus Macaque. E.S. Mohn, N.R. Matthan, J.W. Erdman;
Jr., M. Neuringer, M.J. Kuchan, E.J. Johnson. USDA at Tufts
Univ., Univ. of Illinois at Urbana-Champaign, Oregon Hlth. &
Sci. Univ., Beaverton and Abbott Nutr., Columbus, OH.
D327 I689.3 Lutein Supplementation Increases
Serum Brain-Derived Neurotrophic Factor in Humans. N.T.
Stringham, P.V. Holmes, J.M. Stringham. Univ. of Georgia.
D328 II689.4 Identification and Quantification of
Carotenoids in Various Phenotypic Sorghum Accessions.
Y. Shen, X. Su, X. Chen, D. Rhodes, B. Katz, J. Tomich, W.
Wang. Kansas State Univ. and USDA, Manhattan, KS.
D329 I689.5
Lutein HPLC Method Comparison and
Validation. N.E. Craft, D.G. Springs, J. Chavan. Craft Technol.
Inc., Wilson, NC and OmniActive Hlth. Technol., Mumbai.
D330 II689.6
Low Intake of Fruit and Vegetables,
Body Fatness and Pro-inflammatory/Pro-oxidant Status Are
the Major Determinants of Plasma Carotenoids Reduction in
Free-Living Adults. R.M. Manda, H.T. Kano, G.N. Vilches,
R. Selingardi, L.M. Abe, C.R. Correa, R.C. Burini. Botucatu
Med. Sch., São Paulo State Univ.
D331 I689.7 Carotenoid Profile and Antioxidant
Activity of Tortillas Elaborated from Yellow Creole Maize
(Zea mays L.) by Conventional Nixtamalization Process. S.
Mora-Rochin, A. Corrales Bañuelos, D. Angulo Serrano,
E. Cuevas Rodriguez, C. Reyes Moreno, J. Milan-Carrillo.
Univ. Autonoma de Sinaloa, Mexico.
D332 II689.8Apo-10′-Lycopenoic
Acid
Inhibits
Cancer Cell Migration and Angiogenesis by Suppressing
Lamellipodia Formation. B. Miao, X. Fu, X-D. Wang. USDA at
Tufts Univ.
D333 I689.9
Evaluation of Different Delivery Vehicles
on the Digestion and Absorption of Lutein Using a Lymph
Fistula Rat Model. P. Tso, M. Vurma, D. Lee, S. DeMichele.
Univ. of Cincinnati and Abbott Nutr.
D334 II689.10 In Vivo Assessment of Lutein
Absorption in Infant Formula Using Mono-diglycerides Based
Emulsification Technology. M. Vurma, S. DeMichele, D. Lee, P.
Tso. Abbott Nutr., Columbus, OH and Univ. of Cincinnati.
D335 I689.11Lutein-Supplemented
Formula
Enhances Lutein Accumulation in Brain and Other Tissues in
Infant Rhesus Macaques. S. Jeon, K.M. Ranard, M. Neuringer,
E.E. Johnson, M. Kuchan, E.J. Johnson, J.W. Erdman; Jr.
Univ. of Illinois at Urbana-Champaign, Oregon Hlth. & Sci.
Univ., Beaverson, Abbott Nutr. and USDA at Tufts Univ.
D336 II689.12 Comparison of Vitamin A Total
Body Stores Calculated by Two Retinol Isotope Dilution
Equations with Known Values Derived from Modeling. J.L.
Ford, M.H. Green, J.B. Green, J. Novotny. Penn State and
USDA, Beltsville.
D337 I689.13 Retinoic Acid Pretreatment Promotes
Vitamin A Accumulation in the Lung of Neonatal Rats. Y. Li,
J.K. Urbanek, M.H. Green, L. Tan, A.C. Ross. Penn State and
Univ. of Alabama.
D338 II689.14 Selective Delivery of Xanthophylls to
Human Retinal Pigment Epithelial Cells (ARPE-19) via Human
Lipoproteins. S. Thomas, E.H. Harrison. The Ohio State Univ.
690. DBC: BIOAVAILABILITY, METABOLISM
AND BIOMARKERS OF DIETARY
BIOACTIVE COMPONENTS
Poster
(Sponsored by: Dietary Bioactive Components RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D339 I690.1
Identification
of
Methylated
Avenanthramides in Human Plasma. J. Walsh, J. Haddock,
D.L. McKay, F.W. Collins, J.B. Blumberg, C-Y.O. Chen. USDA
at Tufts Univ. and Agr. and Agri-Food Canada, Ottawa.
D340 II690.2 Nutritional Polyphenol Metabolites’
Kinetics in Plasma, Urine, and Saliva following Consumption
by Normal, Healthy, Subjects. Y.Y. Choy, S.N. Hester, A.
Mastaloudis, S.M. Wood, R. Gray, R.P. O’Donnell, J.L.
Barger, P. Quifer-Rada, R.M. Lamuela-Raventós, A.L.
Waterhouse. Univ. of California, Davis, Nu Skin Enterprises,
Provo, UT, LifeGen Technols., Madison, WI, Univ. of Barcelona
and Inst. of Hlth. Carlos III, Madrid.
D341 I690.3 Resistant Starch Fermentation Is
Prevented by Low Potency Antibiotic Neomycin and Ampicillin.
J.L. Guice, D.G. Carvajal-Aldaz, R.C. Page, A.M. Raggio, R.J.
Martin, C. Husseneder, H.A. Durham, J.P. Geaghan, C.L.
Pelkman, M.L. Marco, M. Janes, D. Coulon, M.J. Keenan. LSU
AgCtr., USDA, Davis, CA, Amway, Baton Rouge, LSU A&M,
Ingredion Inc., Bridgewater, NJ and Univ. of California, Davis.
D342 II690.4
Microbial-Derived Metabolites of Oat
Avenanthramides. A. Yerke, P. Wang, S. Sang. North Carolina
A&T State Univ., Kannapolis.
D343 I690.5
Seven Day Blackberry Feeding Affects
the Energy Substrate Profile in Males and Improves Insulin
Sensitivity. P. Solverson, W.V. Rumpler, J.L. Leger, S.K.
Gebauer, B. Redan, M. Ferruzzi, D.J. Baer, J.A. Novotny.
USDA, Beltsville, MD, Univ. of Maryland College Park and
Purdue Univ.
209
S
U
N
NUTRITIONSUNDAY
D344 II690.6
Validating Polyphenol Intake Estimates
from a Food-Frequency Questionnaire Using Repeated 24Hour Dietary Recalls and a Unique Method of Triads Approach
with Two Biomarkers. N. Burkholder-Cooley, S. Rajaram,
E. Haddad, G.E. Fraser, K. Oda, K. Jaceldo-Siegl. Loma
Linda Univ.
D345 I690.7
Intake of 2 Eggs for Breakfast Increases
Plasma Lutein Concentration in Association with Increased
Large HDL and Zeta Potential as Compared to an Oatmeal
Breakfast. A.C. Missimer, S. Hu, Y. Luo, C.N. Blesso, M-L.
Fernandez. Univ. of Connecticut.
D346 II690.8 Bioavailability
and
Biodistribution
of Fluorophore-Labeled Exosomes from Cow’s Milk after
Intravenous and Oral Administration in C57BL/6J Mice. S.
Manca, D. Giraud, J. Zempleni. Univ. of Nebraska-Lincoln.
D347 I690.9
Metabolic Fate of Curcumin in the
Gastrointestinal Tract in Mice. Z. Li, Y. Sun, M. Song, F. Li, H.
Xiao. Univ. of Massachusetts Amherst.
D348 II690.10 The Physical Stability Comparison of
Two Types of Resveratrol Nanocarriers. Y. Zu, S. Wang. Texas
Tech Univ.
D349 I690.11 Colonic Metabolism of the Common
Dietary Polyphenol Quercetin-3-O-Rutinoside – Impact of Age
and Gut Health. E. Combet, C.A. Edwards, A.A. Alkhaldy.
Sch. of Med., Univ. of Glasgow and King Abdulaziz Univ.,
Saudi Arabia.
D350 II690.12
Is Plasma Plant Sterols a Biomarker of
Plant Sterols Intake Estimated from FFQ and Multiple Dietary
Recalls? R. Sirirat, E. Haddad, A. Mashchak, K. JaceldoSiegl. Loma Linda Univ.
D351 I690.13 Effect of Frequent Broccoli Intake on
Rat Gut Microbiota Metabolism and Composition. Y. Wang, X.
Liu, M.J. Miller, E.H. Jeffery. Univ. of Illinois, Urbana.
D352 II690.14 Site-Specific
Deglucuronidation
of
Turmeric-Derived Curcuminoids in Bone. A.G. Kunihiro, J.B.
Frye, P.B. Luis, C. Schneider, J.L. Funk. Univ. of Arizona and
Vanderbilt Univ.
D353 I690.15
Calcium-Binding Peptides Isolated from
Casein Hydrolysates Enhances Intestinal Calcium Uptake.
J. Miao, G. Liu, Z. Luo, Z. Xia, F. Liu, Y. Chen, W. Dixon, H.
Xiao, Y. Cao. Col. of Food Sci., South China Agr. Univ., Univ.
of Massachusetts Amherst, Infinitus (China) Co. Ltd. and
Guangzhou Greencream Biotech Co. Ltd., China.
D354 II690.16
Oat Avenanthramides Are Bioavailable
in Humans after Acute Consumption of Oat Cookies. T. Zhang,
J. Shao, Y. Gao, C. Chen, D. Yao, M. Wise, C. Kang, D. Yeo,
L.L. Ji. Sch. of Kinesiol., Univ. of Minnesota, Minneapolis, Col.
of Food, Agr. and Animal Sci., Univ. of Minnesota, St. Paul and
USDA, Madison, WI.
D355 I690.17 A Pharmacokinetic Evaluation of the
Duration of Effect of Inositol-Stabilized Arginine Silicate and
Arginine Hydrochloride in Healthy Adult Males. J. Komorowski,
S. Perez Ojalvo. Nutr. 21, LLC, Purchase, NY.
D356 II690.18
Efficacy of Chewing Gum as a Delivery
System for Water and Fat Soluble Vitamins. W.Y.H. Khoo, J.D.
Lambert. Penn State.
D357 I690.19Postprandial
Cranberry
Flavonol
Glycoside Bioavailability in Human Urine. H.N. Nelson, A.J.
Kaiser, N.C. Reker, Y. Wang, A.P. Singh, N. Vorsa, T.L. Hooks,
T. Wilson. Winona State Univ. and Rutgers Univ.
210
D358 II690.20 Acute
Bioavailability
of
(Poly)
phenolic Content of Different Varieties of Vaccinium spp. in
Ovariectomized Rats. M. Maiz, D.P. Cladis, P.J. Lachcik, E.M.
Janle, M.A. Lila, M.G. Ferruzzi, C.M. Weaver. Purdue Univ.
and North Carolina State Univ., Kannapolis.
D359 I690.21 Enhanced Solution Concentration of
Quercetin in Amorphous Solid Dispersions. A. Gilley, H.C.
Arca, B. Nichols, K. Edgar, A.P. Neilson. Virginia Tech.
D360 II690.22
Testing the Use of Urinary Biomarkers
to Assess Added Sugar Intake in Obese Postmenopausal
Women. K. Arnold, J. Bomser, R. Andridge, T. Orchard. The
Ohio State Univ.
D361 I690.23
Metabolomic Analysis Revealed DoseDependent Association between Growth Performance and
Redox Metabolites in Algae Feeding. Y. Ma, W. Zhou, P.
Chen, P.E. Urriola, G.C. Shurson, R. Ruan, C. Chen. Univ. of
Minnesota, Saint Paul.
D362 II690.24 The Mediation of Intracellular Ca2+ by
Resveratrol. J.C. Mecham. Brigham Young Univ.
691. DBC: MECHANISMS OF ACTION AND
MOLECULAR TARGETS OF DIETARY
BIOACTIVE COMPONENTS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D363 I691.1
Javamide-I Found in Coffee Is a Potent
p38 MAP Kinase Inhibitor Suppressing MCP-1 Expression
Significantly in LPS-Stimulated Monocytic THP-1 Cells. J.
Park, T. Wang. USDA, Beltsville, MD.
D364 II691.2
The Heat Shock Protein 70 Is a Novel
Target for Nobiletin in Human Colon Cancer Cells. Z. Gao,
J. Zheng, X. Wu, K. Dimova, S. Scordilis, H. Xiao. Univ. of
Massachusetts Amherst and Smith Col.
D365 I691.3
α-Tocopheryl Phosphate Induces VEGF
Expression via CD36/PI3Kγ/Akt in THP-1 Monocytes. J-M.
Zingg, A. Azzi, M. Meydani. Tufts Univ., Boston.
D366 II691.4
Zinc Transporter 7 Knockout in Mice
Differentially Affects Lipid Metabolism in adipose Tissues. L.
Huang, S. Tepaamorndech, C.P. Kirschke, T.L. Pedersen,
W.R. Keyes, J.W. Newman. USDA, Davis and Univ. of
California, Davis.
D367 I691.5 Naringenin, a Citrus Flavanone,
Enhances Isoproterenol-Stimulated Thermogenic Activation
of 3T3-L1 Adipocytes. L. Zhao, J. Bae, J. Chen. Univ. of
Tennessee, Knoxville.
D368 II691.6 The Regulation in Key Protein
Expression Related to Circadian Rhythms with a Natural
Compound Containing Rosemary and Hemerocallis Fulva
Extract In Vitro. B. Qin, T. Shea-Donohue, C. Liu, J. Quilici
Timmcke, R.A. Anderson. USDA, Beltsville, MD, Iningredients.com, Columbia, TN, Univ. of Maryland Sch. of
Med. and Jiangsu Province Acad. of Traditional Chinese
Med., Nanjing.
SUNDAYNUTRITION
D369 I691.7
Ellagic Acid and Quercetin Are HighAffinity Ligands of Human Peroxisome Proliferator-Activated
Receptor Alpha in an In Vitro Competitive Binding Assay. G.
Sasaki, T. Luo, N.F. Shay. Oregon State Univ.
D370 II691.8
Diosmetin: An Anti-leukemic Flavonoid
Targeting the Estrogen Receptor β S.G. Rota, A. Roma, P.A.
Spagnuolo. Univ. of Waterloo Sch. of Pharm., Canada.
D371 I691.9
Dietary Procyanidins Lower Serum
Triglyceride Levels via Up-Regulation in Pparα and Its
Downstream Target Gene Expression. M-L. Ricketts, L.E.
Downing. Univ. of Nevada Reno.
D372 II691.10 Mango Polyphenols (Mangifera indica
L.) and Their Microbial Metabolites Suppress Adipogenesis
and Fat Accumulation by Mediating AMPK Signaling Pathways
in 3T3L-1 Adipocytes. C. Fang, H. Kim, S.T. Talcott, S.U.
Mertens-Talcott. Texas A&M Univ.
D373 I691.11
Spirulina platensis Organic Extract
Increases Spare Respiratory Capacity in RAW 264.7
Macrophages to Exert an Anti-inflammatory Effect. T.X. Pham,
J-Y. Lee. Univ. of Connecticut.
D374 II691.12 Potentiation of TRPM 5 Leads
to Increased Taste Perception and Insulin Secretion. K.
Philippaert, R. Vennekens. Univ. of Leuven, Belgium.
D375 I691.13
Involvement of Autophagy in Differential
Cytotoxicity of Pterostilbene on Human Bladder Cancer
Cells and Immortalized Human Uroepithelial Cells to FDAApproved Anticancer Drugs. C-L. Su, Y-T. Chen. Natl. Taiwan
Normal Univ.
D376 II691.14 Effects of Curcumin Metabolites on
Human Colon Adenocarcinoma Cells. A-C. Cheng, M-F. Lee,
C-T. Li, K-H. Chang, M-H. Pan. Chang Jung Christian Univ.,
Fooyin Univ. and Natl. Taiwan Univ., Taiwan.
D377 I691.15
Curcumin
Metabolites
Induce
Autophagic Cell Death through PI3K/AKT-mTOR Signaling in
COLO205 Human Colon Adenocarcinoma Cells. A-C. Cheng,
M-F. Lee, B-H. Chiou, Y-Z. Yen, M-H. Pan. Chang Jung
Christian Univ., Tainan, Natl. Kaohsiung Marine Univ. and Natl.
Taiwan Univ., Taipei.
D378 II691.16 Inhibition of High Glucose-Induced
Diabetic Retinal Angiogenesis by Dietary Compound Chrysin.
M. Kang, Y-H. Kang. Hallym Univ., South Korea.
D379 I691.17 Gossypetin Suppresses AcidificationRelated Protein Expression and Lysosomal Enzymes Secretion
in RANKL-Mediated Osteoclasts. L.D. Antika, E-J. Lee, Y-H.
Kang. Hallym Univ. and Korea Food Res Inst., Gyeonggi-do.
D380 II691.18 Astragalin Attenuates Allergic Airway
Inflammation by Modulating Macrophage Infiltration in
Asthmatic Mice. Y-H. Kim, Y.J. Choi, Y-H. Kang. Hallym Univ.
and Ulsan Univ. Col. of Med., South Korea.
D381 I691.19
Protective Effect of Betaine against Liver
Steatosis Involves Depletion of Homocysteine via Upregulation
of Betaine-Homocysteine Methyltransferase. C.W. Ahn, D.S.
Jun, J.D. Na, Y.J. Choi, Y.C. Kim. Seoul Natl. Univ.
D382 II691.20 Role of Acetyl-CoA Metabolizing
Enzyme ACSS2 and Dietary Acetyl-CoA Precursors in
Transcription and Lipid Disorder. R. Moreau, A. Erickson, N.
Bruner, M. Xia, B. He. Univ. of Nebraska - Lincoln.
D383 I691.21 iTRAQ-Based Quantitative Proteomic
Analysis of the Anticancer Mechanism of a Novel Ent-Kaurane
Diterpenoid from Rubus corchorifolius Linn.f X. Chen, Z. Gao,
Y.W. Ou, G. Liu, X. Gao, X. Liu, Y. Chen, L. He, H. Xiao, Y. Cao.
South China Agr. Univ. and Univ. of Massachusetts Amherst.
D384 II691.22 Effects of Resveratrol Derivatives on
Plasma Membrane Ca2+-ATPase and Ca2+ Homeostasis in
MDA-MB-231 Human Breast Cancer Cells. J.A. Peterson, J.D.
Kenealey. Brigham Young Univ.
D385 I691.23 Lycopene
Induces Apoptosis
in
Pancreatic Cancer Cells. Y. Jeong, J.W. Lim, H. Kim. Yonsei
Univ., South Korea.
D386 II691.24 Korean Red Ginseng Extract Inhibits
p53-Dependent Apoptosis In Helicobacter pylori- Infected
Gastric Epithelial Cells. HJ. Kang, J.W. Lim, H. Kim. Col. of
Human Ecol., Yonsei Univ., South Korea.
D387 I691.25
Docosahexaenoic Acid Inhibits Cytokine
Expression through Suppression of NF-κB Activation in Rat
Pancreatic Stellate Cells. H.R. Eum, S.A. Chung, J.W. Lim, H.
Kim. Col. of Human Ecol., Yonsei Univ., South Korea.
D388 II691.26
Activation of AMP Kinase by Zyflamend,
a Well-Defined Blend of Herbal Extracts. A.F. MacDonald, A.F.
Han, D. Donohoe, J. Whelan. Univ. of Tennessee, Knoxville.
D389 I691.27 Genetic
Background
Determines
Anthocyanin Effects on Glutathione Redox Balance. K.M.
Norris, R. Pazdro. Univ. of Georgia.
D390 II691.28
Effects of Pomegranate Extract on High
Fat/High Sucrose Diet-Induced Obesity Are Dependent on the
Intestinal Formation of Urolithin A. J. Yang, S.M. Henning, R.
Lee, M. Hsu, E.M. Grojean, A. Ly, D. Heber, Z. Li. UCLA and
Loyola Marymount Univ.
D391 I691.29 Obesity-Breast Cancer Interactions:
Effects of Adipocytes on Breast Cancer Cells and Preventive
Effects of Omega 3 Fatty Acids. S.A. Alhaj, A. Aljawadi, L.
Ramalingam, N. Moustaid-Moussa. Texas Tech Univ.
D392 II691.30 Unfermented and Fermented Cocoa
Extracts as Inhibitors of Pancreatic α-Amylase, α-Glucosidase,
and Pancreatic Lipase. C. Ryan, L. Ye, S. O’Keefe, A.P.
Neilson. Virginia Tech.
D393 I691.31 Inhibitory Effects of Red Raspberry
Polyphenols on Osteoclastogenesis in RANKL-Stimulated
RAW264.7 Murine Macrophages. A. Thomas, S. South,
V. Imrhan, C. Prasad, P. Vijayagopal, S. Juma. Texas
Woman’s Univ.
D394 II691.32 Proteomic Analysis of Human Serum
of Osteopenic Women after Dried Plum Treatment. F. Lee,
M. Ghassemian, S. Schenk, M. Kern, S. Hooshmand. San
Diego State Univ. and UCSD.
D395 I691.33 Resveratrol and Pterostilbene Inhibit
TNF-α Stimulated Activation of NF-κB and Its Upstream TAK1
in Macrophages via Modulation of Sphingolipids. C. Yang, Q.
Jiang. Purdue Univ.
D396 II691.34 Modulation of Serotonergic Stress
Neurocircuitry by Dietary Prebiotics and Lactoferrin.
M. Chichlowski, A. Mika, B. Berg, M. Fleshner. Mead
Johnson Nutr., Univ. of Colorado Boulder and Univ. of Illinois
D397 I691.35 In Vitro Effects of Grape Phenolics,
Myricetin and Piceatannol, on Bovine Granulosa Cell
Proliferation and Steroid Production. L.J. Spicer, L.F. Schutz,
L. Zhang. Oklahoma State Univ.
D398 II691.36 Beetroot
Extract
Increases
the
Expression of Uncoupling Protein 1 in Primary Brown
Adipocytes In Vitro. D. Otieno, S.G. Lee, H.W. Kang. North
Carolina A&T State Univ.
D399 I691.37 Comparison of Anti-obesity Effects of
Onion Peels by Different Extraction Methods Using 3T3-L1
and Primary Brown Adipocytes In Vitro. S.G. Lee, H.W. Kang.
North Carolina A&T State Univ.
211
S
U
N
NUTRITIONSUNDAY
D400 II691.38 The Chemoprotective Effects of
Mammalian Lignans Enterodiol and Enterolactone in Nontransformed Colonocytes. C. Curry, E. Garcia-Villatoro, D.B.
Hales, C.D. Allred. Texas A&M Univ. and So. Illinois Univ. Sch.
of Med.
D401 I691.39 Drug Treatment of Prostate Cancer
Cells Using a Combination of Naturally Occurring Compounds
Leads to Activation of Apoptosis. R.V. Oblad, A. Dixon, D.
Bernhisel, D. Eggett, J. Kenealey. Brigham Young Univ.
692. DBC: EFFECTS OF DIETARY BIOACTIVE
COMPONENTS ON EXPERIMENTAL MODELS
OF CHRONIC DISEASE RISK
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D402 II692.1
Turmeric Powder Gavage Improves
Lipid Profile of Normal Albino Rats. A.V. Iwueke, K. Iheanacho,
J. Nwodu. Imo State Polytech and Fed. Univ. of Technol.
Owerri, Nigeria.
D403 I692.2
Dietary Tocotrienols Improve Glucose
Homeostasis and Bone Turnover Biomarkers in High-Fat-DietInduced Obese Male Mice. C-L. Shen, G. Kaur, L. Ramalingam,
M.D. Tomison, E. Chung, N. Moustaid-Moussa, C. Guo, C.R.
Web, H. Mo, J.D. Dufour. Texas Tech Univ. Hlth. Sci. Ctr.,
Texas Tech Univ. and Georgia State Univ.
D404 II692.3
Omega-3 Fatty Acid-Rich Fish Oil
Supplementation Prevents Rosiglitazone-Induced Osteopenia
in Insulin Resistant C57BL/6 Mice. M.M. Rahman, G. Halade,
P. Williams. Col. of Arts and Sci., Qatar Univ., Univ. of Alabama
at Birmingham and Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
D405 I692.4
Dietary Quercetin Inhibits MethylglyoxalInduced Advanced Glycation End Products Formation in Mice.
Y. Zhao, P. Wang, H. Chen, S. Sang. North Carolina A&T State
Univ., Kannapolis.
D406 II692.5 Novel Nutritional Formula Protects
against Cellular Damage. S.M. Wood, R. Gray, S.N. Hester,
A.F. Mastaloudis, D. Kern, J. Namkoong, Z.D. Draelos. Nu
Skin Enterprises, Provo, UT and Dermatol. Consult. Svcs.,
High Point, NC.
D407 I692.6
Intake of Whole Raspberries and the
Raspberry Phytochemicals, Ellagic Acid and Raspberry Ketone
Reduces Adiposity, Improves Glucose Control and Changes
Hepatic Gene Expression Profiles in High-Fat Fed Mice. N.F.
Shay, T. Luo, O. Miranda, A. Adamson. Oregon State Univ.
D408 II692.7 Blueberries
Improve
Whole-Body
Insulin Action and Alter the Development of Obesity in HighFat Fed Mice. A.J. Stull, R.A. Beyl. Pennington Biomed. Res.
Ctr., Baton Rouge.
D409 I692.8
Improved Peripheral Insulin Sensitivity
and Pancreatic Islet Function in Obese Rats Treated with
Polyphenol-Rich Extract of Syzygium cumini Leaves. L.M.
França, J.R. Sanches, V.T. Chagas, R.S. Gaspar, K.A. Santos,
M.C.S. Maranhão, E.M. Carneiro, A.P.G. Cappelli, A.M.A.
Paes. Fed. Univ. of Maranhão and Univ. of Campinas, Brazil.
212
D410 II692.9 Cyanidin, a Natural Anti-glycation
Agent, Inhibits Methylglyoxal- and Glucose-Mediated Protein
Glycation In Vitro. T. Suantawee, H. Cheng, S. Adisakwattana.
Chulalongkorn Univ., Thailand and LSU Sch. of Vet. Med.
D411 I692.10 Xylobiose Ameliorates Hyperglycemia
and Dyslipidemia via Regulating Hepatic Lipogenic Genes
in db/db Mice. E. Kim, E. Lim, S. Jung, S-H. Yoo, Y. Kim.
Ewha Womans Univ., TS Corp., Inchon and Sejong Univ.,
South Korea.
D412 II692.11 Phyllodulcin as a Sugar Complement
Exerts Anti-diabetic Effects in db/db Mouse. E. Kim, S-H. Yoo,
Y. Kim. Ewha Womans Univ., BK21 Plus Team, and Sejong
Univ., South Korea.
D413 I692.12
Molecular Effects of Cinnamon Bioactive
Compounds for Neuroprotection in D. melanogaster R. Crews,
Y. Gomada, B. Jamison, D. Vattem. Friedman Sch. of Nutr.
Sci. and Policy, Tufts Univ., Texas State Univ., Fukushima Med.
Univ., Japan and Quality Assurance Village Farms Intl., Dallas.
D414 II692.13 Hypolipidemic and Antioxidant Effects
of Hawthorn Extract in Pre- and Postmenopausal Rats. Y. Liu,
J-H. Yoo, E-J. Ko, H. Jeong, H-S. Kim. Sookmyung Women’s
Univ., South Korea.
D415 I692.14 Induced the Down-Regulation of
Adipogenesis-Related Genes of Bacterial β-Glucan in High Fat
Diet-Induced Obese Rats. S.A. Kang, J.A. Kim, H-S. Kim, T-S.
Kim, J-K. Kim, B. Hwang, J-Y. Lee. Hoseo Univ., South Korea.
D416 II692.15 Improved Osteoporotic Condition of
Soybean and Yak-kong (Blackbean: Rhynchosia molubilis) in
Korean Postmenopausal Women. S.A. Kang, K-G. Jung, S-H.
Kim, J-G. Park, M-H. Seo, J-H. Cha, H-J. Oh, J-Y. Lee. Hoseo
Univ., Seoul and Asan, South Korea.
D417 I692.16 The Effect of Guava Leaf Extracts on
Antioxidant Properties and Lipid Profile in Ovariectomized Rats.
Y. Liu, E-J. Ko, J-H. Yoo, E-K. Song, H-S. Kim. Sookmyung
Women’s Univ., South Korea.
D418 II692.17 Evaluating the Effect of Plant Origin
Prebiotics (Raffinose and Stachyose) on Iron Status, Intestinal
Functionality and Intestinal Bacterial Populations In Vivo.
S. Pacifici, J. Song, C.K. Zhang, E. Tako. Cornell Univ. and
USDA, Cornell Univ.
D419 I692.18
Effects of Stevioside on Oxidative DNA
Damage in Liver and Kidney of High Fat Diet-Induced Type
2 Diabetes in Rats. S.O. Rotimi, O.A. Rotimi, P.O. Obi, C.D.
Onuzulu, O.O. Ogunlana, T.M. Dokunmu, W.O. Iyanda-Joel.
Covenant Univ., Nigeria.
D420 II692.19 Effects of Naringin on Hepatic
Paraoxonase Activity and Lipid Metabolism in Type 2 Diabetic
Rats. S.O. Rotimi, I.B. Adelani, G.E. Bankole, O.A. Rotimi.
Covenant Univ., Nigeria.
D421 I692.20 Acute Effects on Satiety from White
Button and Shiitake Mushroom Powder Supplementation
in a High Fat Meal. T.J. Robak, L.A. Talal, M.J. Morris, B.T.
Williams, R.W. Browne, P.J. Horvath. Univ. at Buffalo.
D422 II692.21 The Effect of Oil Palm Phenolics on
Urinary Metabolomic Profile In Atherogenic Diet-Induced Rat
Model of Alzheimer’s Disease. Y. Wu, V. Srirajavatsavai,
R. Sambanthamurthi, S.V. Gupta. Wayne State Univ. and
Malaysian Palm Oil Board, Kuala Lumpur.
D423 I692.22
β-Alanine Supplementation Improved
Workload Capacity and Cognitive Function of Middle Age
Individuals. T. Furst, B. Williams, A. Massaro, C. Miller, P.J.
Horvath. Univ. at Buffalo SUNY.
SUNDAYNUTRITION/PATHOLOGY
D424 II692.23Effects
of
Raspberry
Dietary
Supplementation on Risk Biomarkers of Diabetes-Related
Complications and Heart Disease in Diabetic Mice. G. Noratto,
B. Chew, A. Mencia. Texas A&M Univ. and Washington
State Univ.
D425 I692.24Resveratrol
Attenuates
Obesity
Related Renal and Systemic Alterations during Acute and
Chronic Endoplasmic Reticulum Stress. C. Tovar-Palacio, M.
Terán-García, E. Figueroa-Juarez, I. Torre-Villalvazo, L.G.
Noriega, A.R. Tovar, R. Correa-Rotter. Salvador Zubirán Natl.
Inst. of Hlth. Sci. and Nutr., Mexico City and Univ. of Illinois
D426 II692.25 Blueberry Supplementation Impacts
Gut Microbiota, Inflammatory Profiles, and Insulin Sensitivity in
High-Fat Fed Rats. S. Lee, R. Kirkland, J.G. Fischer, C. de La
Serre. Univ. of Georgia.
D427 I692.26 Effects of Sphingomyelin-Rich Beta
Serum on Lipid Metabolism in High Fat Diet-Fed Mice. G.H.
Norris, C.N. Blesso. Univ. of Connecticut.
D428 II692.27
The Acute Effects of White Button and
Shiitake Mushroom Powder Supplementation on Postprandial
Lipemia following a High Fat Meal M.J. Morris, T.J. Robak,
L.A. Talal, B.T. Williams, R.W. Browne, P.J. Horvath. Univ.
at Buffalo.
D429 I692.28 Supplementation of Whole Flaxseed
Reduced Hepatic Steatosis in Aged Laying Hens. J.E. Davis,
J. Cain, C. Small, D.B. Hales. Sch. of Med., So. Illinois Univ.
Carbondale and Aurora Univ.
D430 II692.29 Early Detection of Nonalcoholic Fatty
Liver Disease Utilizing a Novel QUS Method. J.L. Rowles, R.J.
Miller, A. Han, M.A. Wallig, W.D. O’Brien; Jr., J.W. Erdman;
Jr. Univ. of Illinois at Urbana-Champaign.
Pathology
693. EDUCATION IN PATHOBIOLOGY
695. STEM CELLS
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
Presentation time: 11:45 am–1:45 pm
A193 693.1
Specialist Program in Pathobiology: An
Undergraduate Program in Mechanisms of Disease. A.
Gotlieb, D. Templeton. Univ. of Toronto.
694. TRANSLATIONAL RESEARCH
Poster
Exhibit Halls A-D
A194 694.1
Potential
Pathological
Implication
of
Osteocalcin and Vitamin D in Acute Aortic Dissection. M.M.
Corsi Romanelli, E. Vianello, A. Barassi, S. Trimarchi, E.
Dozio. Univ. of Milan and IRCCS Policlin. San Donato, Italy.
A195 694.2
Preclinical Safety Profile of a Depleting
Antibody Against CRTh2 for Asthma: Well Tolerated Despite
Unexpected CRTh2 Expression on Vascular Pericytes in the
Central Nervous System and Gastric Mucosa. C.D. Austin,
T. Huang, N. Sharma, S. Liu, M. Solon, A. Reyes, S. Paul,
A. Yee, J. Tao, S. Chalasani, N. Bien-Ly, K. Barck, R.A.D.
Carrano, J. Wang, L. Rangell, M. Bremer, D.M. Danilenko, P.
Katavolos, I. Hotzel, K. Reif, K.S. Rajapaksa. Genentech Inc.
A196 694.3
Intraperitoneal Post-operative Adhesions in
Rats Are Worsened by Opiate Administration. G.M. Bove, S.L.
Chapelle, D.J. Mokler. Univ. of New England and Squamish
Integrated Hlth., Canada.
A197 694.4
F93D Mutation in HDAC4 N-Terminal
Glutamine-Rich Domain and Its Effect on Photoreceptor
Survival. M.C. Juarez, V. Sample, C. Cepko. Lehigh Univ. and
Harvard Med. Sch.
A198 694.5
Urocortin 3 Gene Transfer Increases LV Peak
-dP/dt in Normal Mice. D. Giamouridis, N.C. Lai, M. Gao, E.
Biessen, M. Blankesteijn, H.K. Hammond. Maastricht Univ.,
Netherlands, Veterans Med. Res. Fndn., San Diego and UCSD.
A199 695.1
ATF6 Promotes Early Stem Cell Development.
H. Kroeger, W-C. Chiang, R.L. Wiseman, J.H. Lin. UCSD and
The Scripps Res. Inst.
A200 695.2
Bone Morphogenic Protein 2 Is a Key
Regulator of Spheroidal Aggregates of Mesenchymal Stem
Cells K. Tamama, J. Funnell, Z. Cesarz. Univ. of Pittsburgh
Sch. of Med.
696. BIOMARKERS AND TARGETED THERAPY
Poster
Exhibit Halls A-D
A201 696.1
Validation of a Quantitative Polymerase Chain
Reaction-Based Method for Detecting Lymph Node Metastasis
by Melanoma Cells. T.B. Goodloe III, K.M. Hargadon.
Hampden-Sydney Col., VA.
A202 696.2
Vasculogenic Mimicry in Non-functioning
Pituitary Adenomas: Fact or Fallacy? F. Rotondo, J. Di
Michele, K. Kovacs, L.V. Syro, G.M. Yousef, M.D. Cusimano,
A. Di Ieva. St. Michael’s Hosp., Toronto, Hosp. Pablo Tobon
Uribe & Clin. Medellin, Colombia, Australian Sch. of Adv. Med.,
Macquarie Univ. Hosp., Sydney and Garvan Inst. of Med.
Res., Sydney.
A203 696.3
Inaccurate Quantitation of IgM Monoclonal
Proteins: A Cause for Concern. E.W. Holmes, B. Bahar, B.M.
Whisler, M. Gryzbac, S.E. Kahn. Loyola Univ. Med. Ctr.
A204 696.4
CD44, CD133 and Lgr5 as Biomarkers for
Early Detection of H. pylori-Associated Gastric Cancer. R.
Walker, J. Mejia, H. Enderling, J.M. Pimiento, M. Malafa, D.
Coppola. Moffitt Cancer Ctr., Tampa and Pathol. Inst. Mejia
Jimenez, Colombia.
213
S
U
N
PATHOLOGYSUNDAY
A205 696.5
A New Composite Biomarker for Cervical
Cancer Diagnosis. O. Markovic, N. Markovic. Global Acad. for
Women’s Hlth. and BioSciCon Inc., Rockville, MD.
697. TUMOR PROGRESSION METABOLISM
AND METASTASIS
Poster
Exhibit Halls A-D
A206 697.1
Modeling Melanoma as In Vitro Artificial Tumor
Tissues Using Natural 3D Matrix Materials. T. Lyden, M.
Martin. Univ. of Wisconsin-River Falls.
A207 697.2
Indoleamine2,3-Dioxygenase
Inhibition
Decreases VEGF-A Expression in Human Bladder Cancer
Cells and Diminishes Angiogenesis in Coculture with Human
Umbilical Vein Endothelial Cells. C.S. Malta, R.B. de Oliveira
Brito, Y.T. Matos, D.M. de Souza, L.H. Matheus, H. Dellê.
Univ. Nove de Julho, São Paulo.
A208 697.3
Diphenolic Acid in Plastics Activates
Smoothened Receptor. K. Kandhwal, I. Kufareva, M. Parle, R.
Abagyan. Guru Jambheshwar Univ. of Sci. and Technol., India
and Skaggs Sch. of Pharm. and Pharmaceut. Sci., UCSD.
A209 697.4
Renal Subcapsular Space of Balb/c Nude
Mice as a Route to Evaluate Differentiation of Human Bladder
Carcinoma T24 Cells Subpopulations. D.M. Souza, L.H.G.
Matheus, R.B. Brito, Y.S.T. Matos, C.S. Malta, J.M. Ferreira,
C.S. Silva, H. Dellê. Nove de Julho Univ., São Paulo.
A210 697.5
Cigarette Smoke-Induced Bladder Cancer
Initiation. J. McHowat, J. Marentette. Saint Louis Univ. Sch.
of Med.
A211 697.6
Implications for Platelet Activating Factor
Receptor Antagonism for Managing Bladder Cancer
Progression. J. McHowat, J. Marentette. Saint Louis Univ.
Sch. of Med.
A212 697.7
TIMP-2 Deficiency Alters Host Immune
Response in Murine Lung Tumor Microenvironment. S.M.
Jensen, S. Kumar, A. Chowdhury, B. Wei, W.G. StetlerStevenson. NCI, NIH, Gaithersburg, MD.
A213 697.8
HPV Related Squamous Cell Carcinomas of
the Head and Neck Metastatic to the Small Bowel: First Case
Report and Review of the Literature. A.P. Patel, K.G. Neill, M.
Leon, D. Coppola. Univ. of South Florida and Moffitt Cancer
Ctr., Tampa.
698. BREAST, GYNECOLOGICAL, AND
PROSTATE CANCER
Poster
Exhibit Halls A-D
A214 698.1
Lactate Dehydrogenase A May Not Be
Primarily Responsible for Maintaining High Tumor Lactic Acid
Levels in Aggressive Breast Cancer. N. Mack, E. Mazzio, K.
Soliman. Florida A&M Univ.
214
A215 698.2
TIMP-2: A Novel Biologic Therapy for Triple
Negative Breast Cancer. N.P. Castro, A. Chowdhury, S.M.
Jensen, F. Cuttitta, W.G. Stetler-Stevenson, D. Solomon.
NCI at Frederick and NCI at Shady Grove, MD.
A216 698.3
Control of Breast Cancer through the Resolution
of Inflammation. D.R. Vatnick, K. Lehner, M. Gilligan, D.
Panigrahy, Y. Gus-Brautbar, S. Ramon, S. Huang, C. Serhan.
Beth Israel Deaconess Med. Ctr., Harvard Med. Sch., Brigham
and Women’s Hosp. and Inst. for Systs. Biol., Seattle.
A217 698.4
PAF/PAF-R Expression and Effects of Cigarette
Smoke Exposure in Human Breast Cancer. S.E. Kispert, T.
Schwartz, J. McHowat. Saint Louis Univ. Sch. of Med.
A218 698.5
The Histone Deacetylase Sirt2 Regulates Slug
in Basal-Like Breast Cancer. W. Zhou, C. Kuperwasser. Tufts
Univ. Sch. of Med. and Tufts Univ.
A219 698.6
Breast Tumor Development and Cigarette
Smoking: Accelerated Tumor Development in Calcium
Independent Phospholipase A2γ Deficient Mice. S.E. Kispert,
J. McHowat. Saint Louis Univ. Sch. of Med.
A220 698.7
A Novel Synthetic Tumor Platform for Screening
Drug Delivery Systems. Y. Tang, F. Soroush, S. Deosarkar, B.
Wang, P. Pandian, M.F. Kiani. Temple Univ., Widener Univ.
and CFD Res. Corp., Huntsville, AL.
A221 698.8
Breast Cancer Emergence from Dormancy
Can Be Activated by Hepatic Stellate Cells. A.S. Khazali,
A. Clark, S. Wheeler, A. Wells. Univ. of Pittsburgh and VA
Pittsburgh Healthcare Syst.
A222 698.9
Expression and Function of Androgen
Receptor in Human Breast Cancer-Associated Fibroblasts:
May Androgens Shape Breast Tumor Microenvironment? M.
Lanzino, A. Campana, C. Giordano, I. Barone, D. Bonofiglio,
S. Catalano, S. Andò. Univ. of Calabria, Italy.
A223 698.10 Characterizing Breast Cancer Stem Cell
Populations In Vitro Using the Sore6 Gene Reporter System.
D. Li, D.I. Yi, S. Park, G. Liang, M. Kabbout, J. Byun, K.
Gardner. NIMHD and NCI, NIH.
A224 698.11 The Role of CtBP in Tumor Progression:
Insights from the Pinducer Inducible Gene Expression System.
D.I. Yi, D. Li, S. Park, L. Crawford, G. Liang, M. Kabbout, R.
Hernandez-Mora, T. Yan, J. Byun, K. Gardner. NCI, NIH.
A225 698.12 PEDF Reduction Induced by Cigarette Smoke:
A Potential Role for Breast Tumor Development. S.E. Kispert,
J. McHowat. Saint Louis Univ. Sch. of Med.
A226 698.13 Exploring the Proteomic and Genomic
Relationships between CtBP Expression and Metabolic
Imbalance in Breast Cancer. L. Crawford, R. Hernandez-Mora,
S. Park, J.S. Byun, K. Gardner. NIMHD, NIH and NCI, NIH.
A227 698.14 Apigenin Attenuates CCL2 Release from TNFα
and IL-1a Stimulated MDA-MB-231 Triple Negative Breast
Cancer Cells. D.F. Bauer, E.A. Mazzio, K.F. Soliman. Col. of
Pharm. and Pharmaceut. Sci., Florida A&M Univ.
A228 698.15 Characterizing Bone Tropism of Human
ER+ Breast Cancer Cell Lines in a Murine Bone Metastasis
Model. J.N. Cheng, J.B. Frye, S.A. Whitman, J.L. Funk. Univ.
of Arizona.
A229 698.16 The Influence of the Social Support about 20s
Women’s Cervical Cancer Screening Who Are Doing Physical
Activities on the Screening Attitude. K. Yunhwa. Asan City,
South Korea.
A230 698.17 Leptin Association with Prostate Cancer and
HIV Infection – A Double Edge Sword. R.G. Andavolu, C.
Stafford, M.V.S. Andavolu. Genet. Res. Inst. of the Desert and
Eisenhower Med. Ctr., Rancho Mirage, CA.
SUNDAYPATHOLOGY
A231 698.18 The Role of Indoleamine 2,3-Dioxygenase
on PC-3 Prostate Cancer Cells Viability. Y.S.T. Matos, R.B.O.
Brito, L.H.G. Matheus, D.M. Souza, C.S. Malta, D. GiannellaNeto, J. Pontes-Junior, H. Dellê. Univ. Nove de Julho,
São Paulo.
A232 698.19 Androgen Receptor Represses the Expression
of Minichromosome Maintenance Proteins: A Mechanism
for Androgen Therapy in Castration Resistant Prostate
Cancer. K. Valencia, D. Han, S. Gao, W. Han, C. Cai. Univ. of
Massachusetts Boston.
A233 698.20 Foxi3: A Sly Regulator of Bone Development,
Promotes Prostate Cancer. A. Mukherjee. Troy Univ., AL.
699. LUNG CANCER
Poster
Exhibit Halls A-D
A234 699.1
FSTL1 Inhibits Tumor Growth and Metastatic
Progression via Blocking Proteolytic Activation of SPP1 in
Lung Adenocarcinoma. J. Chiou, C-Y. Su, Y-F. Lin, M. Hsiao.
Genomics Res. Ctr., Acad. Sinica, Taipei, China Med. Univ. and
Col. of Med., Taipei Med. Univ., Taiwan.
A235 699.2
Pharmacogenomic Analysis of Adenylate
Kinase-4 Gene Expression Signature Identifies Withaferin-A as
an Anti-metastatic Agent in Non-small Cell Lung Cancer. Y-H.
Jan, M. Hsiao. Genomics Res. Ctr. Acad, Sinica, Taipei.
A236 699.3
Anti-angiogenic Activity of Nicotinic Receptor
Antagonists in Lung Cancer. Z. Robateau, K.C. Brown, R.G.
Creel, Y.C. Chen, L.M. Grover, E.I. Mangiarua, R.D. Egleton,
P. Dasgupta. Joan C. Edwards Sch. of Med., Marshall Univ.
and Alderson Broaddus Univ., WV.
A237 699.4
Analysis of the Acetylcholine-Signaling
Pathway Reveals Differences between Normal and Malignant
Lung Tissue. K.C. Brown, J.K. Lau, B.A. Thornhill, H.E. Perry,
D.V. Jones, J.F. Pulliam, J. Martin, P. Dasgupta. Joan C.
Edwards Sch. of Med., Marshall Univ., Dana-Farber Cancer
Inst. and Markey Cancer, Lexington, KY.
A238 699.5
Anti-invasive Activity of Capsaicin and Nonpungent Capsaicin Analogs in Human SCLC. A.T. Akers,
J.D. Hurley, K.C. Brown, N.A. Nolan, P. Dasgupta. Joan C.
Edwards Sch. of Med., Marshall Univ.
A239 699.6
Acetylcholine-Signaling Inhibitors for Lung
Cancer Therapy. P. Dasgupta, J.K. Lau, K.C. Brown, W.D.
Rollyson, C.A. Stover, J.M. Rimoldi, S.J. Cutler, W.E.
Hardman, A.B. Carpenter, Y.C. Chen. Joan C. Edwards Sch.
of Med., Marshall Univ., Univ. of Mississippi and Alderson
Broaddus Univ., WV.
A240 699.7
Combinatorial Apoptotic Activity of Capsaicin
and Camptothecin in Small Cell Lung Cancer. C.A. Stover,
H.E. Perry, K.C. Brown, W.D. Rollyson, P. Dasgupta. Joan C.
Edwards Sch. of Med., Marshall Univ.
A241 699.8
Role of the Transcription Factor Yin Yang 1
in Non-small Cell Lung Cancer. O. Boucherat, S. Chabot, A.
Bourgeois, S. Provencher, R. Paulin, F. Maltais, S. Bonnet.
Univ. Inst. of Cardiol. and Pneumol. of Québec, Univ. Laval.
700. LUNG PATHOBIOLOGY
Exhibit Halls A-D
A242 700.1
Cardio-respiratory
Development
in
Juvenile Sprague-Dawley Rats: A Histomorphologic and
Immunohistochemical Study. V. Vrolyk, A. Apreutese, C.
Gordon, R. Forster, A. Graham, B. Palate, J. Haruna, M-O.
Benoit-Biancamano. Univ. of Montreal, St.-Hyacinthe,
CiToxLAB, Laval and CiToxLAB France, Evreux.
A243 700.2
Losartan Blocks the Recruitment of Mast Cells
in the Lungs of Rats Subjected to Fat Embolism with or without
a Second Hit with LPS. A. Poisner, S. Hamidpour, A. Ho, P.
Skaria, A. Fletcher, S. Simon, A. Molteni. Univ. of Kansas
Med. Ctr. and Univ. of Missouri Kansas City.
A244 700.3
Regulation of Lysophosphatidic Acid Receptor
1 Stability Modulates Cytokine Release in Lung Injury. Y. Zhao,
J. Wei, S. Dong, R.K. Bowser, L. Zhang, A.M. Jacko, J. Zhao.
Univ. of Pittsburgh.
A245 700.4
TGF-Beta Induces the Expression of Scleraxis
in Lung Fibroblasts from Idiopathic Pulmonary Fibrosis. M.
Ramirez Aragon, M.A. Blancas Oropeza, F. Hernandez
Sanchez, A. Cruz Lagunas, M.P. Czubryt, C. Mendoza Milla.
UNAM and INER, Mexico City and Inst. of Cardiovasc. Sci.,
Winnipeg, Canada
A246 700.5
Kinetics and Implications of Germinal Center
Formation in Induced Bronchus-Associated Lymphoid Tissue
during Influenza Infection. K.N. Gibson-Corley, A.W. Boyden,
L. Tygrett, T.J. Waldschmidt. Univ. of Iowa.
A247 700.6
BLES-Cath-2 Intratracheal Administration in
an In Vivo P. aeruginosa Pneumonia Model. J.M. Nicholson,
B. Banachewski, L. McCaig, E. Veldhuizen, C. Yamashita,
R. Veldhuizen. Western Univ., Canada and Utrecht
Univ., Netherlands.
A248 700.7
Pulmonary Dipeptidyl Peptidase-4 Expression
in Lung: Relevance in Experimental Models and for Middle
East Respiratory Syndrome Clinical Disease. D.K. Meyerholz,
P.B. McCray; Jr.
Univ. of Iowa Carver Col. of Med.
701. NON-NEOPLASTIC AND ORGAN
PATHOBIOLOGY POSTERS
Poster
Exhibit Halls A-D
A249 701.1
NLRP3 Inflammasome as a Novel Target
for Docosahexaenoic Acid and Its Metabolites to Abrogate
Glomerular Injury during Hyperhomocysteinemia. Z. Chen,
S.M. Conley, G. Li, M. Xia, T.W. Gehr, K.M. Boini, P-L. Li.
Virginia Commonwealth Univ.
A250 701.2
ATP-Binding Cassette Transporter ABC1 Is
Decreased in Skeletal Muscle from Insulin-Resistant Mice. P.
Llanos, P. Sanchéz, H. Cerda-Kohler, M. Arias-Calderón, A.
Diaz-Vegas, C. Campos, A. Contreras-Ferrat, C. Hidalgo, E.
Jaimovich. Fac. of Odontol., Univ. of Chile.
A251 701.3
Activity of Sphingomyelinase in Plasma, Urine,
and Tissues of Diabetic Rats. R. Bautista-Pérez, R. PérezVillavicencio, L. del Valle-Mondragón, O. Pérez-Méndez, M.
Franco. Natl. Inst. of Cardiol. - Ignacio Chávez, Mexico.
Poster
215
S
U
N
PATHOLOGY/PHARMACOLOGYSUNDAY
A252 701.4
The Effects of 4-Methylumbelliferone on
Hyperglycemia in Type 2 Diabetic Mice. J.S. Edwards, V.
Sunkari, P. Bollyky. Sch. of Life Sci., Rochester Inst. of
Technol. and Stanford Univ.
A253 701.5
Investigating the Mechanism of Autoimmune
Disease-Associated LQTS: Anti-Ro52 IgG Decreases
hERG Channel Density. J.A. Szendrey, S. Zhang. Queen’s
Univ., Canada.
A254 701.6
A Novel Assay to Screen Porcine Mhc Class
II Antibodies in Potential Xenotransplant Recipients. J.M.
Ladowski, J. Butler, G. Martens, L. Reyes, Z-Y. Wang, J.
Tune, M. Tector, A.J. Tector. Indiana Univ. Sch. of Med. and
Indiana Univ. Hlth.
A255 701.7
Generating Hypertrophic Adipocytes from 3T3
L1 Cell Line and Characterizing the Phenotypic Transition. X.
Yuan, X. Xu, N. Li, W. L. Dewey, P-L. Li, F. Zhang. Med. Col.
of Virginia.
A256 701.8
Weight Management in Primary Care Validated
by Evidence-Based Algorithm. D.G. Jacks, G.P. Einstein, O.L.
Tulp. Univ. of Sci. Arts & Technol., Montserrat.
702. PATHOBIOLOGY OF AGING
Poster
Exhibit Halls A-D
A257 702.1
Effects of Melatonin and Beta-Amyloid on
Mitochondrial Function in a Model of Aging Mouse Astrocytes.
E.K. Debner, J.M. King. Trinity Univ.
Pharmacology
703.CANNABINOIDS
Poster
Exhibit Halls A-D
Behavioral Pharmacology
A1
703.1
Delta-9-Tetrahydrocannabinol
SelfAdministration in Male and Female Long Evans Rats. A.G.P.
Wakeford, B.B. Wetzell, R.L. Pomfrey, M. Clasen, W. Taylor,
A.L. Riley. American Univ.
A2
703.2
Novel Synthetic Cannabinoid AB-PINACA
Produces THC-Like Behavioral and Cellular Effects through
Activation of the Cannabinoid CB1 Receptor. S. Tai, J. Crane,
B.M. Ford, P.L. Prather, W.E. Fantegrossi. Univ. of Arkansas
for Med. Sci. and Middlebury Col., VT.
A3
703.3
Behavioral Characterization of Spiradoline
and CP55,940 in Rats: Potential of Drug Mixtures for Treating
Pain. V. Minervini, C.P. France. Univ. of Texas Hlth. Sci. Ctr.,
San Antonio.
A4
703.4
Daily Synthetic Cannabinoid Agonist (JWH018) Treatment: Tolerance to Δ9-Tetrahydrocannabinol-Like
Discriminative Stimulus Effects in Rhesus Monkeys. M.L.
Cocke, L.R. McMahon. Univ. of Texas Hlth. Sci. Ctr. at
San Antonio.
A5
703.5
Comparison
of
Heroinand
?9-Tetrahydrocannabinol-Induced Antinociception and Physical
Dependence in Monkeys. H. Ding, N. Kiguchi, S. Kishioka,
M-C. Ko. Wake Forest Sch. of Med. and Wakayama Med.
Univ., Japan.
A6
703.6
Physiological and Pharmacokinetic Effects
of E-Cigarette Type Exposure to Δ9-Tetrahydrocannabinol.
J.D. Nguyen, S.M. Aarde, S.A. Vandewater, Y. Grant, D.G.
Stouffer, L.H. Parsons, M. Cole, M.A. Taffe. Scripps Res. Inst.
and La Jolla Alcohol Inc.
A7
703.7
Increases in Locomotor Activity during
Spontaneous Cannabinoid Withdrawal in Mice. J.A. Bergman,
C.G. Reingold, C.E. Barkin, N.R. Bergman, S.P. Nikas, A.
Makriyannis, C.A. Paronis. McLean Hosp./Harvard Med.
Sch., Belmont and Northeastern Univ.
216
A8
703.8
The Effects of Δ9-Tetrahydrocannabinol (THC)
Drug History on THC Taste and Place Conditioning. B. Hempel,
A. Wakeford, M. Clasen, M. Friar, A. Riley. American Univ.
A9
703.9
Characterization of the Behavioral Phenotypes
Underlying the Reinforcing Effects of Cannabinoid Receptor
Agonists in Rhesus Monkeys. W. John, M. Nader. Wake Forest
Sch. of Med.
A10
703.10 Mechanisms of Tolerance to Delta-9-THC in
Rodent Models of Pathological Pain. D. Morgan, M. Yuill, M.L.
Zee, R. LaFleur, J. Guindon. Penn State Col. of Med. and
Texas Tech Univ. Hlth. Sci. Ctr.
704.ALCOHOL
Poster
Exhibit Halls A-D
A11
704.1
Impact of Chronic Ethanol Self-Administration
on Kappa Opioid Receptor Regulation of Dopamine Signaling
in Nonhuman Primates. C.A. Siciliano, E.S. Calipari, S.C.
Fordahl, J.R. Melchior, J.T. Yorgason, Y. Mateo, C.M. Helms,
V.A. Jimenez, D.M. Lovinger, K.A. Grant, S.R. Jones. Wake
Forest Sch. of Med., NIAAA, NIH, Rockville and Oregon Hlth.
& Sci. Univ.
A12
704.2
The Serotonin 2A Receptor Agonist
2,5-Dimethoxy-4-Iodoamphetamine
Reduces
Ethanol
Consumption and Place Conditioning. K.S. Murnane, P.
Nakhla, K. Curry, J. Phillips, C. Daphney. Mercer Univ. Col.
of Pharm. and Oglethorpe Univ.
A13
704.3
Sex Differences in Alcohol-Induced HPA
Activation following Systemic versus icv Administration in
Rats: Gene Expression Studies. A. Wakley, S. Davis, P. Yap,
C. Pham, D.J. Selvage. Univ. of New England.
A14
704.4
Pharmacological Reversal of Adolescent
Alcohol-Induced Perturbation to Mesolimbic Dopamine
Network Dynamics Rescues Maladaptive Decision Making in
Adulthood. A. Schindler, M. Soden, S. Weber, L. Zweifel, J.
Clark. Univ. of Washington.
SUNDAYPHARMACOLOGY
A15
704.5
Effect of Oral Augmentin on Glutamate
Transporter-1 Expression Levels as Well as Ethanol Intake
in Alcohol-Preferring Rats. A.Y. Hakami, F.S. Alshehri, Y.S.
Althobaiti, Y. Sari. Univ. of Toledo.
A16
704.6
Tianeptine Co-administration with Alcohol to
Adolescent Rats Modifies the Alcohol Withdrawal Syndrome.
D.E. Rhoads, B. Martin, M. Mauterer, K. Orlando.
Monmouth Univ.
A17
704.7
Modeling Chronic Alcohol-Stimulant Couse Shows Dampening of Alcohol Withdrawal Severity.
A.J. Nanchanatt, S. Popkin, M. Mauterer, D.E. Rhoads.
Monmouth Univ.
A18
704.8
Adenosine A2A Receptor Driven Impulsivity
Promotes Cue-Dependent Reward Seeking Behavior and
Increases Hippocampal Immature Neurons. A. Oliveros, C.H.
Cho, S. Choi, M-H. Jang, D-S. Choi. Mayo Clin.
705. HYPEREXCITABILITY AND NEUROIMMUNITY
Poster
Exhibit Halls A-D
Neuropharmacology
A19
705.1
A Novel, A-2, 3-Selective GABAA Receptor
Modulator with Improved Central Penetrability and Associated
Antiepileptic and Anti-pain Efficacy. J.M. Witkin, K.R. Methuku,
J.M. Schkeryantz, S.D. Gleason, A. Okun, F. Porreca, J.W.
Cramer, T.M. Jones, J.T. Catlow, X. Li, M.M. Poe, G. Li,
A. Arnold, J.M. Cook. Lilly Res. Labs., Univ. of WisconsinMilwaukee and Univ. of Arizona.
A20
705.2
Role of Extracellular Matrix Protein FibronectinIntegrin Signaling in the Hippocampal Dentate Gyrus in
Epilepsy. X. Wu, B. Clossen, M. Muthuchamy, D. Reddy.
Texas A&M Hlth. Sci. Ctr. Col. of Med.
A21
705.3
Neurotensin
Depresses
GABA
type-B
Receptor-Mediated Neurotransmission in the Substantia Nigra
through Pre- and Postsynaptic Mechanisms. C.W. Tschumi,
M.J. Beckstead. Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
A22
705.4
The Neurotoxic Effects of Manganese
on Dopamine Post-Synaptic Receptors Are Reversed by
p-Aminosalicylic Acid. L. Dubose, K. Loney-Walsh, M.A.
Carroll, E.J. Catapane. Medgar Evers Col., NY.
A23
705.5
Serine 216 Regulates ERα to Repress
Inflammation in Microglia of Mouse Brains. S. Shindo. NIEHS,
NIH, Research Triangle Park, NC.
A24
705.6
The Effects of ARVs on ARG-iNOS Pathway
in the Brain: Does the Interaction Play a Role in Microglial
Activation? Emilia Laudati, Lisi Lucia, Cinzia Dello Russo and
Pierluigi Navarra Institute of Pharmacology, Catholic University
Medical School E. Laudati, L. Lucia, C. Dello Russo, P.
Navarra. Catholic Univ. Med. Sch., Rome.
A25
705.7
Cannabinoids Are Neuroprotective against
HIV-1 Tat and Occlude the Tat-Induced Decrease in GABAergic
Neurotransmission in Prefrontal Cortex Slices. C. Xu, D.J.
Hermes, K. Mackie, A.H. Lichtman, B.M. IgnatowskaJankowska, S. Fitting. Univ. of North Carolina at Chapel Hill,
Indiana Univ., Virginia Commonwealth Univ. and Hebrew Univ.
of Jerusalem.
A26
705.8
Long-Term Administration of Methamphetamine
in Tat Mice Causes Altered Behavior and Neuroplasticity Gene
Expression – Implications in NeuroAIDS. A.R. Nookala, A.
Kumar. Univ. of Missouri-Kansas City.
706. NEURONAL INJURY: SCI, STROKE AND TBI
Poster
Exhibit Halls A-D
Neuropharmacology
A27
706.1
PPAR-α Modulates the Anti-inflammatory
Effect of Melatonin in the Secondary Events of Spinal Cord
Injury. I. Paterniti, M. Campolo, M. Cordaro, D. Impellizzeri,
R. Siracusa, R. Crupi, E. Esposito, S. Cuzzocrea. Univ.
of Messina.
A28
706.2
mTOR
Pathway
Inhibition
Prevents
Neuroinflammation and Neuronal Death in a Mouse Model of
Spinal Cord Injury. E. Esposito, M. Cordaro, I. Paterniti, D.
Impellizzeri, R. Siracusa, S. Cuzzocrea. Univ. of Messina and
Manchester Royal Infirm., Sch. of Med., Univ. of Manchester.
A29
706.3
Activation of the Cannabinoid Receptor 2 by
JWH133 Attenuates Neurological Deficits and Brain Edema
after Experimental Intracerebral Hemorrhage in Mice. L.O.
Iniaghe, S.R. Burchell, J.H. Zhang, J. Tang. Univ. of Benin,
Nigeria and Loma Linda Univ.
A30
706.4
Astrocyte Mitochondrial Trifunctional Protein
Mediates the Neuroprotective Effect of Thyroid Hormone after
Stroke in Mice. M. Sifuentes. Univ. of Texas Hlth. Sci. Ctr. at
San Antonio.
A31
706.5
The Effect of BPC 157 on Ischemic/reperfusion
Injuries in Rat Brain. J. Vukojevic, B. Vrdoljak, D. Malekinusic,
D. Zaler, D. Kolenc, M. Siroglavic, G. Aralica, D. Drmic, S.
Seiwerth, P. Sikiric. Sch. of Med., Univ. of Zagreb, Croatia.
A32
706.6
A Multi-herbal Extract HT047 Promotes LongTerm Functional Recovery after Focal Cerebral Ischemia in
Rats. J. Song, D. Lee, Y-S. Kim, H.S. Kim, H. Lee, S. Lee, S.H.
Lee, H. Kim. Col. of Korean Med., Kyung Hee Univ., Korea Inst.
of Sci. and Technol. for Eastern Med. and NeuMed Inc., Seoul.
A33
706.7
Targeting Trauma-Induced Blood Brain Barrier
Disruption: An Innovative Approach for Treating Concussion.
B. Lucke-Wold, A. Logsdon, R. Turner, M. Robson, P.
Lockman, C. Rosen. West Virginia Univ. and Vanderbilt Univ.
A34
706.8
Co-ultra PEALut Enhances Neuronal Recovery
after a Moderate Traumatic Brain Injury. M. Campolo, R.
Crupi, M. Cordaro, G. Bruschetta, R. Siracusa, E. Esposito,
S. Cuzzocrea. Univ. of Messina.
217
S
U
N
PHARMACOLOGYSUNDAY
707. DRUG AND GENE THERAPIES FOR
COGNITIVE DISORDERS
Poster
Exhibit Halls A-D
Neuropharmacology
Drug Discovery and Development
A35
707.1
Development of Cathepsin B Positive
Modulators to Treat Multi-proteinopathic Dementias: Exploiting
the Lysosomal Avenue of Protein Clearance to Promote
Synaptic Recovery. M.C. Pait, L. Elliott, S. Hafner-Ruiz, C.
Mundell, W. Patterson, H. Romine, U. Ikonne, B.A. Bahr.
Univ. of North Carolina-Pembroke and A.T. Still Univ.
A36
707.2
The α2 Adrenergic Receptor as a Novel Target
for Alzheimer’s Disease. M. Gannon, Y. Peng, K. Jiao, Q.
Wang. Univ. of Alabama at Birmingham.
A37
707.3
Neurochemical Profile of a Novel Allosteric
Potentiator of the Dopamine D1 Receptor. J.F. Falcone, S.N.
Mitchell, G. Carter, D.L. Maren, J. Katner, E. Chernet, R.A.
Wright, H. Wang, J.W. Ryder, M. Morin, D.R. Gehlert, M.P.
Johnson, J.P. Beck, J. Hao, M.M. Menezes, R.F. Bruns, K.A.
Svensson. Eli Lilly & Co., Indianapolis and Erl Wood, U.K.
A38
707.4
miR-146a Contributes to Dementia-Like
Pathology by Upregulation of Prion Protein in Type-2 Diabetes.
A. Kalani, C.J. Mallonee, G. Chu, N. Tyagi. Univ. of Louisville.
A39
707.5
Cocaineand
Amphetamine-Regulated
Transcript Peptide Alleviates the Cognitive Deficits following
MK-801-Induced Schizophrenia. C.D. Borkar, A.P. Bharne,
N.K. Subhedar, D.M. Kokare. R.T.M. Nagpur Univ., India and
Indian Inst. of Sci. Educ. and Res., Pune.
A40
707.6
Memory Enhancement Induced by PDE2
Knockdown in an Alzheimer’s Disease Model of Mice. Y. Xu,
Z. Chen, J. Pan, H-T. Zhang, J.M. O’Donnell. Univ. at Buffalo,
SUNY, Changzhou Second People’s Hosp., China, Wenzhou
Med. Univ., China and West Virginia Univ.
A41
707.7
Deficiency of Macrophage Migration Inhibitory
Factor Attenuates Tau Hyperphosphorylation in Mouse Models
of Alzheimer’s Disease. R.D. Ye. Univ. of Macau, China.
A42
707.8
Correcting Memory Deficits in Fragile X
Syndrome by Targeting Rac1/PAK1 Signaling. L. Martinez,
M.V. Tejada-Simon. Univ. of Houston.
A43
707.9
Chronic Antagonism of p38α MAPK Normalizes
Serotonin Clearance, Serotonin Receptor Hypersensitivity and
Social Behavior Deficits in a Genetic Murine Model of Autism
Spectrum Disorder. M.J. Robson, M.A. Quinlan, J. VeenstraVanderWeele, D.M. Watterson, R.D. Blakely. Vanderbilt Univ.,
Columbia Univ. and Northwestern Univ., Chicago.
218
708. PARKINSON’S DISEASE THERAPEUTICS
Poster
Exhibit Halls A-D
A44
708.1
In Vitro Characterization of a Novel Allosteric
Potentiator of the Dopamine D1 Receptor. B.A. Heinz, J.M.
Schaus, J.P. Beck, J. Hao, X. Wang, J. Krushinski, M.
Reinhard, S. Hellman, B. Getman, T. Suter, D. Nelson, T.
Wiernicki, M.P. Cohen, C.R. Yang, K.A. Svensson, R.F.
Bruns. Eli Lilly and Co. and Shanghai Chempartner.
A45
708.2
Behavioral Effects of a Novel Allosteric
Potentiator of the Dopamine D1 Receptor in Human D1 KnockIn Mice and Rhesus Monkeys. K.A. Svensson, J.P. Beck, J.
Hao, J.M. Schaus, D.L. Maren, M.M. Menezes, J.F. Falcone,
W. Anderson, K. Knopp, B.L. Adams, J.M. Witkin, X. Li, J.
Cramer, A.J. Harper, K.A. Wafford, L. Zhang, C.R. Yang,
R.F. Bruns. Eli Lilly, Indianapolis and Erl Wood, U.K. and
Chempartner, Shanghai.
A46
708.3
Investigation of Dithiolethione 59 as Potential
Neuroprotective Antiparkinsonian Agent. S. Betharia, D.
Brown, S. Fuentes, I. Aoude. Manchester Univ. Col. of Pharm.
and Nat. and Hlth. Sci., IN.
A47
708.4
Opicapone Improves the Effects of L-DOPA on
the MPTP-Induced Parkinson’s-Like Syndrome in Cynomolgus
Monkeys. M.J. Bonifacio, S. Medakkar, F. Sousa, J.A. Vivian,
P. Soares-da-Silva. BIAL Portela & Cia, Portugal, Maccine Pte
Ltd., Singapore and MedInUp and Fac. of Med., Porto, Portugal.
A48
708.5
Effects of UCH-L1 Inhibition in Immortalized
Dopaminergic Neurons. B.M. Winner, H. Zhang, J. Goudreau,
K. Lookingland. Michigan State Univ.
709. ORPHAN GPCRS, GPCROMICS,
ADHESION GPCRS
Poster
Exhibit Halls A-D
Molecular Pharmacology
A49
709.1
Loss of GGPR37 Increases Susceptibility
to Demyelination. B.M. Coleman, F. Li, M.M. Giddens, R.A.
Hall. Emory Univ. Sch. of Med. and Neurorepair Therapeut.,
Research Triangle Park, NC.
A50
709.2
Loss of Brain-Expressed Receptors GPR37
and/or GPR37L1 Results in Increased Seizure Susceptibility to
Induced Seizures. M.M. Giddens, J.C. Wong, B.M. Coleman,
J.P. Schroeder, E.G. Farrow, S.E. Soden, D. Weinshenker, A.
Escayg, R.A. Hall. Emory Univ. and Children’s Mercy Hosp.,
Kansas City, MO.
A51
709.3
Stalk-Dependent
and
Stalk-Independent
Activity of the Adhesion GPCR GPR56/ADGR. G1 A. Kishore,
R.A. Hall. Emory Univ. Sch. of Med.
A52
709.4
The BAI Sub-Family of Adhesion GPCRs: New
Insights into Regulation and Signaling. R.H. Purcell, R.A. Hall.
Emory Univ.
SUNDAYPHARMACOLOGY
A53
709.5
Identification of a First-In-Class Adhesion
G Protein-Coupled Receptor Orthosteric Antagonist. H.
Stoveken, A. Smrcka, G.G. Tall. Univ. of Rochester Med. Ctr.
A54
709.6
Deorphanizing Renal Olfactory Receptor 1393
B.D. Shepard, Z. Peterlin, S. Firestein, J.L. Pluznick. Johns
Hopkins Univ. Sch. of Med. and Columbia Univ.
A55
709.7
Studies of Ectopically Expressed Olfactory
Receptor Olfr558/PSGR2: Gene Expression, Function
and Novel Molecular Probes. A. Pronin, C-H. Volmar, M.
Giulianotti, S. Brothers, V.Z. Slepak. Univ. of Miami and
Torrey Pines Inst. for Molec. Studies, Port St. Lucie, FL.
A56
709.8
GPCRs as Novel Targets in Pulmonary Artery
Smooth Muscle Cells in Pulmonary Arterial Hypertension. K.
Sriram, N. Aroonsakool, A.V. Michkov, P.A. Insel. UCSD.
A57
709.9
GPCRomics of Cardiac Fibroblasts and
Cardiac Fibrosis. K. Sriram, A.V. Michkov, N. Aroonsakool,
P.A. Insel. UCSD.
A58
709.10 GPCRs Expressed by Cancer-Associated
Fibroblasts Are Potential Therapeutic Targets in Pancreatic
Cancer. S. Zhou, S. Chang, T. McCann, H. Nishihara, R.
French, A. Lowy, P. Insel. UCSD and Hokkaido Univ.
A59
709.11 GPCRs as Possible Therapeutic Targets in
Pancreatic Cancer. S. Chang, T. McCann, S. Zhou, R. French,
A.M. Lowy, R. Corriden, P.A. Insel. UCSD and UCSD Health.
710. GPCR SIGNALING
Poster
Exhibit Halls A-D
A60
710.1
Changes in Brainstem Protein Levels during
the Development and Decay of Tolerance to Morphine: Focus
on PKC&γ B.G. Thompson, J.M. McKeel, D.A. Taylor. Brody
Sch. of Med., East Carolina Univ.
A61
710.2
Heat Shock Protein 90 Regulates μ-Opioid
Receptor Signaling In Vitro and in Different Regions of Mouse
Brain. W. Lei, N. Mullen, S. McCarthy, C. Brann, P. Richard, J.
Cormier, K. Lindros, K. Edwards, E. Bilsky, J.M. Streicher.
Univ. of Arizona and Univ. of New England.
A62
710.3
Cannabinoid Receptor 2 Stimulation Enhances
Bactericidal Activity of Human Neutrophils. M.B. Wiley, V. Nizet,
P.A. Insel, R. Corriden. Univ. of Mount Union, OH and UCSD.
A63
710.4
Identification of Potential PAR-Regulating
Proteinases in Agricultural Dust Using an Activity-Based Serine
Proteinase Probe. M.D. Hollenberg, D. Polley, M. Saifeddine,
B. Gilmore, D.J. Romberger, A.J. Heires, T.M. Nordgren,
M.L. Toews. Univ. of Calgary, Canada, Sch. of Pharm., Queens
Univ. Belfast, U.K. and Univ. of Nebraska Med. Ctr.
A64
710.5
Internalization of Protease-Activated Receptor
4 Is AP-2 Dependent and Utilizes a Non-canonical Sorting
Motif. T.H. Smith, L. Coronel, M. Nieman, J. Trejo. UCSD and
Case Western Reserve Univ.
A65
710.6
RNA-Seq Based Transcriptome Profiling of
Human and Mouse Dorsal Root Ganglion Reveals a Potential
Role for Protease Activated Receptor 3 in Pain Processing. T.
Price, A. Torck, P. Ray, S. Hassler, J. Hoffman, S. Boitano, G.
Dussor, J. Vagner. Univ. of Texas at Dallas, Richardson and
Univ. of Arizona.
A66
710.7
Investigation of Signaling Pathways Activated
by Cocaine- and Amphetamine-Regulated Transcript Peptide
in PC-12 Cells. S. Prinster, A. Kothari, X. Wang. Touro Univ.,
NV and Col. of Med., Western Univ. of Hlth. Sci.
A67
710.8
Constitutive Phosphorylation of STAT3 by the
Human Serotonin 2C Receptor. M.E. Curtis, L. Fears, M. Ivy,
H. Fentress. Tennessee State Univ.
A68
710.9
Specificity and Mechanisms for Induction of
PDE4 Up-Regulation by PGE2 and Related Agents in Lung
Fibroblasts. M.L. Toews, N.A. Schulte, R.S. Ostrom, S.I.
Rennard. Univ. of Nebraska Med Ctr., Univ. of Tennessee Hlth.
Sci. Ctr., Memphis and AstraZeneca, Melbourn, U.K.
A69
710.10 Bitter Taste Receptor Agonists as Potent
Tocolytics for Preterm Labor. K. Zheng, P. Lu, T.A. Moore
Simas, E. Delpapa, L.M. Lifshitz, F. Shi, R. ZhuGe. Univ. of
Massachusetts Med. Sch. and Nanjing Agr. Univ.
A70
710.11 The GPCR CXCR4 and Tyrosine Phosphatase
SHP2 Interact and Signal via a Novel Consensus Motif. L.T.
Belcastro, R.D. Paulukinas, A. Jancina, C.C. Moore. Univ. of
the Sciences and Wistar Inst., Philadelphia.
A71
710.12 Alpha-1D-Adrenoceptors
Lacking
Their
Carboxyl Terminus Inhibit the MAPK/ERK Pathway in Rat-1
Fibroblasts. M.A. Alfonzo-Méndez, J.A. Castillo-Badillo, M.T.
Romero-Ávila, J.A. García-Sáinz. IFC, UNAM, Mexico City.
A72
710.13 Compartmentalized cAMP Response to
Prostaglandin EP2 Receptor Activation in Human Airway
Smooth Muscle Cells. R.D. Harvey, K. Miyashiro, S.R.
Agarwal, H. Latt, R.S. Ostrom. Univ. of Nevada, Reno, Univ.
of Nevada Sch. of Med. and Univ. of Tennessee Hlth. Sci.
Ctr., Memphis.
A73
710.14 Identifying New Players and Pathways
Involved in Receptor-Mediated Heterologous Sensitization of
Adenylyl Cyclase Using Genome-Wide siRNA and BiFC Library
Screening. T.B. Doyle, K.F.K. Ejendal, M. Soto Velasquez, N.
Santoro, S. Choudhari, M.J. Larsen, J. Thimmapuram, C-D.
Hu, V.J. Watts. Purdue Univ. and Univ. of Michigan.
A74
710.15 Regulation of Ric-8A by Dephosphorylation
Downstream of Ras Signaling. M.M. Papasergi-Scott, B.
Patel, M. Gabay, G. Tall. Univ. of Rochester.
A75
710.16 Modulation of the Facilitatory Effect of
Dopamine at the Neuromuscular Junction by Adenosinergic
and Purinergic Receptors. H.E. AlQot, N.A. Elnozahi,
M.M. Mohy El-Din, A.E. Bistawroos, M.S. Abou Zeit-Har.
Alexandria Univ. Fac. of Pharm., Egypt.
711.NEPHROTOXICITY
Poster
Exhibit Halls A-D
Toxicology
A76
711.1
The Anti-viral Agent Tenofovir Induces
Oxidative Stress and Apoptosis in HK-2 Cells. R. Murphy, R.
Stafford, B. Petrasovits, M. Boone, M. Valentovic. Marshall
Univ Sch. of Med. and West Virginia Wesleyan Col.
A77
711.2
Protective Effect of Resveratrol on Mitochondria
and Oxidative Stress Induced by Cisplatin in HK-2 Cells. M.
Valentovic, R. Murphy, A.B. Lamyaithong, R. Stafford, A.
Schnelle, J.G. Ball. Marshall Univ Sch. of Med.
219
S
U
N
PHARMACOLOGYSUNDAY
A78
711.3
Nephrotoxic Potential of 3,5-Dichloroaniline
Putative Metabolites in Isolated Renal Cortical Cells from
Fischer 344 Rats. G. Rankin, C. Racine, D. Ward, C. Tyree, D.
Pope, D. Anestis. Marshall Univ.
A79
711.4
Molecular Mechanisms of All-trans-Retinoic
Acid Mediated Cytoprotection against Renal Cell Injury. J.M.
Sapiro, K.L. Burrell, S.S. Lau. Univ. of Arizona.
A80
711.5
Increased Tubular Dysfunction and Injury
Response Biomarkers in the Absence of Overt Clinical
Nephrotoxicity in Cancer Patients Receiving Cisplatin Therapy.
B. George, X. Wen, N. Johnston, M. Gomez, L. Ellison, M.
Joy, L. Aleksunes. Rutgers Univ., Piscataway and Univ. of
Colorado, Aurora.
A81
711.6
N-Acetylcysteine Decreases the Susceptibility
to Diclofenac-Induced Nephrotoxicity in Diabetic Patients. C.H.
Yeh. Da-Yeh Univ., Taiwan.
A82
711.7
Renoprotective Effects of 4-Phenylbutyrate
against Palmitate-Induced Renal Cell Injury. S. Munusamy, D.I.
Alkhiyami, S. Berzou, A. Gholamhussain, H.A.A. Mohamed,
A. Saleh. Col. of Pharm. and Col. of Arts and Sci., Qatar Univ.
A83
711.8
Experimentally Induced Chronic Kidney
Disease in Rats, and the Influence of Curcumin Thereon. B.H.
Ali, S. Al-Salam, M.H. Al Za’abi, Y. Al Suleminai, A. Nemmar.
Sultan Qaboos Univ., Oman, Al Ain, United Arab Emirates and
Al Khod, Oman.
A84
711.9
Evaluation of Protein Biomarkers for Renal
Toxicity Induced by Exposure to Low-Dose Heavy Metals. Y-J.
Shin, J-H. Kim, H-S. Kim, O-N. Bae. Col. of Pharm., Hanyang
Univ. and Col. of Pharm., Sungkyunkwan Univ., South Korea.
A90
712.6
Predicting Fetal Exposure to Drugs throughout
Pregnancy Using a PBPK Model. Z. Zhang, M.Z. Imperial, G.I.
Patilea-Vrana, J. Wedagedera, G. Lu, J.D. Unadkat. Univ. of
Washington and Simcyp Ltd (a Certara Co.), Sheffield, U.K.
A91
712.7
Toxicokinetics of Domoic Acid in Cynomolgus
Monkeys. J. Jing, R. Petroff, B. Crouthamel, K. Grant,
T. Burbacher, N. Isoherranen. Univ. of Washington and
Washington Natl. Primate Res. Ctr., Seattle.
A92
712.8
Cytochrome P450 Enzymes Involved in the
Primary Metabolism of the Novel Constitutive Androstane
Receptor Inhibitor, CINP. A1 M.T. Cherian, L. Yang, S.C. Chai,
W. Lin, T. Chen. St Jude Children’s Res. Hosp.
A93
712.9
Distribution, Metabolism and Elimination of
Opicapone in the Rats and Non-human Primates. A. Loureiro,
C. Fernandes-Lopes, P. Soares-da-Silva. BIAL, Portela
e Companhia SA, Coronado and Inst. of Pharmacol. and
Therapeut., Porto
A94
712.10 Development of a New Practical Approach to
Perform Single-Mouse Pharmacokinetic Study. J.L. Jilek, Y.
Tian, A-M. Yu. Univ. of California, Davis Sch. of Med.
A95
712.11 Absence of Age-Related Differences in Internal
Dosimetry of Deltamethrin at Low Exposure Levels. C. Chen.
Univ. of Georgia.
A96
712.12 Analysis of Drug-Drug Interactions Caused
by the Inhibition of Hepatic Organic Anion Transporting
Polypeptides Using a Rational Physiologically Based
Pharmacokinetic Model and Parameters Obtained from Human
Hepatocytes. T. Yoshikado, K. Toshimoto, Y. Sugiyama.
RIKEN Innovation Ctr., Yokohama.
712. PHARMACOKINETICS AND TOXICOKINETICS
713. REGULATION OF DRUG
METABOLIZING ENZYMES
Poster
Exhibit Halls A-D
Drug Metabolism
A85
712.1
No Longer “The Dog That Did Not Bark”:
Discovery of Xenobiotic Phosphorylation Metabolism of a
TNKS-Wnt Inhibitor When Dosed to Mice or Incubated in
Mouse Whole Blood. C. Gu, P. Doig, E. Gangl, J.W. Johannes,
S. Wen. AstraZeneca.
A86
712.2
A
Multi-scale
Systems
Pharmacology
Approach for Personalizing Irinotecan Chronotherapy. A.
Ballesta, S. Dulong, R. Dallmann, P. Innominato, F. Lévi.
Univ. of Warwick, U.K. and INSERM Unit 935, Villejuif.
A87
712.3
Pharmacokinetics and Pharmacodynamics of
Bioengineered miR-34a Prodrug. P.Y. Ho, W-P. Wang, Q-X.
Chen, B. Addepalli, P.A. Limbach, M-M. Li, J.L. Jilek, J-X.
Qiu, H-J. Zhang, T. Li, T. Wun, R. DeVere White, K.S. Lam,
A-M. Yu. UC Davis, Sacramento, Univ. of Cincinnati and Univ.
of Buffalo.
A88
712.4
Use of Age-Dependent Carboxylesterase 1
Protein Expression to Predict In Vitro Elimination and In Vivo
Pharmacokinetics of Oseltamivir in Infants. M. Boberg, A.
Mehrotra, M. Vrana, B. Prasad. Univ. of Washington and Univ.
of Gothenburg, Sweden.
A89
712.5
Pharmacokinetic Analysis of Aerosol Propellant
HFA-134a Elimination in the Human Breath. H-W. Shin, E.M.
Landaw, B. Barletta, S. Meinardi, S. Aizik, S-Y. Leu, D. Blake,
D.M. Cooper. Univ. of California Irvine and UCLA.
220
Poster
Exhibit Halls A-D
Drug Metabolism
A97
713.1
Transcriptional Regulators Predict CYP3A4
Expression in Human Pediatric Liver. C.A. Vyhlidal, C. Bi, S.Q.
Ye, J.S. Leeder. Children’s Mercy Hosp., Kansan City, MO.
A98
713.2
Nitric Oxide Stimulates CYP51A1 Down
Regulation. A. Byrd, C-m. Lee, J.W. Park, E.T. Morgan.
Emory Univ.
A99
713.3
High Fat Diet Feeding Alters Expression of
Hepatic Drug-Metabolizing Enzymes in Mice. M. Ning, H.
Jeong. Univ. of Illinois at Chicago.
A100 713.4
Fenofibrate Upregulates SHP Expression but
Does Not Alter CYP2D6 Expression. R. Kent, H. Jeong. Col.
of Pharm., Univ. of Illinois at Chicago.
A101 713.5
Cholic Acid Feeding Increases CYP2D6
Expression in CYP2D6-Humanized Mice. R. Kent, X. Pan, H.
Jeong. Col. of Pharm., Univ. of Illinois at Chicago.
A102 713.6
C-Jun-N-Terminal Kinase: Novel Regulator
of PXR-Mediated CYP3A4 Induction. G. Taneja, C. Chu, B.
Moorthy, R. Ghose. Univ. of Houston and Baylor Col. of Med.
A103 713.7
Induction of Xenobiotic Metabolizing Enzymes
and Transporters in Human Intestinal Cells by PregnancyRelated Hormones. J.E. Moscovitz, G. Herrera-Garcia, G.L.
Guo, L.M. Aleksunes. Rutgers Univ., Piscataway and Robert
Wood Johnson Med. Sch., New Brunswick.
SUNDAYPHARMACOLOGY
A104 713.8
Structure-Activity Analysis of EfavirenzMediated Activation of Pregnane X Receptor. J.M. Lade, N.N.
Bumpus. Johns Hopkins Univ. Sch. of Med.
A105 713.9
Sex-Dependent Expression of Cytoprotective
Elements in the Kidney in Response to a Hepatotoxic Dose
of Acetaminophen. D. Cooper, K.M. Flores, J.L. Renfro, J.
Manautou. Vassar Col., NY and Univ. of Connecticut.
A106 713.10 The Temporal Expression and Regulation of an
Imprinted Gene Network during Postnatal Liver Development
in Mice. S. Piekos, L. Peng, X. Zhong. Univ. of Connecticut.
A107 713.11 Age-Dependent Expression Analysis of Major
Drug Metabolizing Enzymes in Human Liver. A. Mehrotra,
M. Boberg, M. Vrana, A. Gaedigk, R.E. Pearce, S. Leeder,
B. Prasad. Univ. of Washington, Univ. of Gothenburg and
Children’s Mercy Kansas City and Sch. of Med., Univ. of
Missouri-Kansas City.
A108 713.12 Neonatal Phenobarbital Exposure Results in
Decreased Proton Pump Inhibition by Omeprazole in Adult
Mouse Y.C. Tien, C. Pope, S. Piekos, X-b. Zhong. Univ.
of Connecticut.
714. CELL SIGNALING AND CANCER BIOLOGY
A116 714.8
CaMKK2 Activates Oncogenic Akt in Ovarian
Cancer Cells and Is a Promising Therapeutic Target. A.M.
Gocher, G. Azabdaftari, L. Karacosta, T.F. Franke, A.M.
Edelman. Univ. at Buffalo, SUNY, Roswell Park Cancer Inst.
and NYU.
A117 714.9
Serum Starvation Induces a Rapid Increase
of Akt Phosphorylation in Ovarian Cancer Cells. S. Dai, A.
Gocher, L. Euscher, A. Edelman. Univ. at Buffalo, SUNY.
A118 714.10 Establishment of Induced Ovarian Cancer
Stem Cells by Defined Factors. Y-A. Chen, C-Y. Lu, W-F.
Cheng, N-s. Chang, H-N. Ho, H-F. Chen. Col. of Med., Natl.
Taiwan Univ. and Natl. Cheng Kung Univ., Taiwan.
A119 714.11 Ablation of Neuropilin 1 in Glioma-Associated
Macrophages Slows Tumor Progression. J.T. Miyauchi, D.
Chen, J. Nissen, K. Shroyer, D. Selwood, S. Tsirka. Stony
Brook Univ. and University Col. London.
715. CANCER THERAPY AND IMMUNOTHERAPY
Poster
Exhibit Halls A-D
Poster
Cancer Pharmacology
Exhibit Halls A-D
Cancer Pharmacology
A109 714.1
c-Jun N-Terminal Kinase 2 Contributes to the
Tumorigenesis of Non-small Cell Lung Carcinoma through
MKK4-Dependent and MKK7-Independent Mechanism. T.S.
Kaoud, L. Du, K.Y. Tsai, K.N. Dalby. Univ. of Texas at Austin,
Fac. of Pharm., Minia Univ., Egypt and Univ. of Texas MD
Anderson Cancer Ctr.
A110 714.2
Proteinases, Proteinase-Activated Receptors
and Transient Receptor Potential Ion Channels: Driving
Tumorigenesis in the Bladder Cancer Microenvironment. S.
Gibson, K. Mihara, M. El-Daly, M. Saifedine, M.D. Hollenberg,
M.E. Hyndman. Univ. of Calgary, Snyder Inst. for Chronic Dis.,
Cumming Sch. of Med. and Prostate Cancer Ctr., Calgary.
A111 714.3
A Novel CXCR4-ARF1-MAPK Signaling
Pathway Controls Prostate Tumorigenesis. J.E. Davis, W.H.
Wu, K. Surrao, Y. Teng, G. Wu. Georgia Regents Univ.
A112 714.4
Impact of Palmitic Acid and α-Linolenic Acid
on the β-Catenin Pathway with Inhibition of the Peroxisome
Proliferator-Activated Receptor &γ (PPAR&γ) in HCT116
Colon Cancer Cells. M.C. Myers, L. Wetmore. William Jewell
Col., MO.
A113 714.5
Epac1 Links Prostaglandin E2 to β-Catenin
Transcriptional Activity during Epithelial-to-Mesenchymal
Transition in A549 Cells. S. Jansen, W. De Jager, S.J.
Yarwood, F. Lezoualc’h, R. Gosens, M. Schmidt. Univ. of
Groningen, Netherlands, Univ. of Glasgow, U.K. and Univ.
Toulouse III, France.
A114 714.6
MRTF-A and YAP Exert Dual Control in GPCR
and RhoA-Mediated Transcriptional Regulation and Cell
Proliferation. O.M. Yu, S. Miyamoto, J.H. Brown. UCSD.
A115 714.7
Electrophilic Nitroalkenes Inhibit Triple
Negative Breast Cancer Metastasis. C-S. Woodcock, S.R.
Woodcock, C. Cao, N.E. Davidson, Y. Huang, B.A. Freeman.
Univ. of Pittsburgh, Sch. of Med. and Univ. of Pittsburgh
Cancer Inst.
A120 715.1
Synergism of Aldehydes and Cytotoxic
Chemotherapy. J.S. Miles, H. Flores-Rozas. Florida A&M Univ.
A121 715.2
Synergistic Interaction of Histone Deacetylase
Inhibitors with Interferon-β in Inducing Apoptosis of Human
Neuroblastoma Cells. S. Dedoni, M.C. Olianas, P. Onali. Univ.
of Cagliari.
A122 715.3
Plasticity of Bone Marrow-Derived Dendritic
Cells as Immunotherapy Vaccines. P. Jungsuwadee. Sch. of
Pharm., Fairleigh Dickinson Univ.
A123 715.4
In Vitro Validation of Cancer Immunotherapy
Reagents Using an Impedance-Based Platform. F. Cerignoli,
J. Zhu, G. Guenther, C. Radecke, B. Xi, L. Zhao., Y. Abassi.
ACEA Biosci. Inc., San Diego.
A124 715.5
Multi-dynamics Mathematical Function and
Matrixes in Stimulation Immune System. F.U. Izunobi, G.P.
Einstein. Col. of Med., Einstein Med. Inst. Corp. USA.
716. SEX DIFFERENCES IN CARDIOVASCULAR
PHARMACOLOGY AND DISEASE
Poster
Exhibit Halls A-D
Cardiovascular Pharmacology
A125 716.1
Sex-Based Differences in the Aortic Function
of UCD-T2DM Rats: A Novel Rat Model of Type 2 Diabetes
Mellitus. F. Akther, S. Shaligram, M.D. Karimi, J.L. Graham,
K.L. Stanhope, P.J. Havel, R. Rahimian. Sch. of Pharm., Univ.
of Pacific and Univ. of California, Davis.
A126 716.2
GPER-1 Agonist Reduces Angiotensin-II
Induced Oxidative Stress in Rat Aortic Smooth Muscle Cells.
J.L. Duong, T.P. Baker, P. Katakam, S.H. Lindsey. Tulane Univ.
221
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PHARMACOLOGYSUNDAY
A127 716.3
Estrogen-Induced Superoxide Production in
Coronary Artery Endothelial Cells via Uncoupled Nitric Oxide
Synthase in Diabetes. J. Winkler, H. Ma, S. Zhu, M. Owen, R.
White. Philadelphia Col. of Osteo. Med. - Georgia Campus.
A128 716.4
The Effects of Sex and Genotype on the
Population Pharmacokinetics and Pharmacodynamics
Modeling and Simulation of Low Dose Epinephrine and Cardiac
Output. A.R. Eugene, M. Joyner. Mayo Clin.
A129 716.5
Sex Specific Differences in Key Signaling
Pathways Involved in Sympathetic Nervous System
Control within the Dorsal Medulla of Adult Sheep with Fetal
Betamethasone Exposure. A.S. Hendricks, D.I. Diz, H.A.
Shaltout, M.C. Chappell. Wake Forest Sch. of Med.
A130 716.6
Sex
Differences
in
Sympathetic
Neurotransmission in Normotensive Rat Mesenteric Arteries.
K. Gebremedhin, J.J. Galligan, H. Xu. Michigan State Univ.
A131 716.7
Sexual Dimorphism in Left Ventricular and
Electrocardiographic Effects of Chronic Cyclosporine in Rats.
M.M. El-Mas, H.M. El-Bassossy, Z.M. Banjar. Alexandria
Univ., Egypt, King Abdulaziz Univ., Saudi Arabia and Zagazig
Univ., Egypt.
A132 716.8
Modulation by NADPH Oxidase/Rho-Kinase
Oxidative Pathway of Chronic Cyclosporine-Diclofenac
Hemodynamic Interaction in Female Rats. M.M. El-Mas, K.S.
Ibrahim, A.F. El-Yazbi, N.M. El-Deeb, H.M. El-Gowelli. Fac. of
Pharm., Alexandria Univ., Egypt.
A133 716.9
Investigation of the Influence of Sex on
Cantharidin-Induced Inflammation in Healthy Volunteers.
K.S. Rathod, U. Siddiqui, A. Hartley, R.S. Khambata, A.
Ahluwalia. Barts & The London Sch. of Med. & Dent. and
Queen Mary Univ. London.
A134 716.10 Gender Differences in the Cardiac Action of
Tyramine but Not Cathinone in the Rat. J.R. Docherty, H.A.
Alsufyani. Royal Col. of Surgeons in Ireland.
717.OBESITY
Poster
Exhibit Halls A-D
A135 717.1
Buprenorphine-Induced
Respiratory
Depression Varies as a Function of Leptin-Related Genotype in
Normal Weight and Obese Mice. C. Angel,W. Alami, S. Mihalko,
H.A. Baghdoyan, R. Lydic. Univ. of Tennessee, Knoxville.
A136 717.2
Identification of Novel Probiotics to Modify
Appetite and Satiety Directly Targeting the Ghrelin Receptor.
C. Torres Fuentes, H. Schellekens, N. Hoevenaars, P. Ross,
B. Roy, C. Stanton, T.G. Dinan, J.F. Cryan. University Col.
Cork,Teagasc Food Res. Ctr., Fermoy, Ireland and CREMO
SA, Fribourg, Switzerland.
A137 717.3
Genetic Inhibition of Chac1 Leads to
Dysregulation of Body Composition. R.R. Crawford, E.T.
Prescott, I.N. Mungrue. LSU Hlth. Sci. Ctr., New Orleans.
A138 717.4
Chronic Paroxetine Treatment in Mice Leads
to Adiposity and Glucose Intolerance. W. Zha, J. Wang. Univ.
of Washington.
A139 717.5
Adipocyte-Derived
Factors
Affect
Cardioprotective Programs Initiated by Short-Term High Fat
Feeding. L. Haar, K. Luther, X. Ren, Y. Wang, W.K. Jones.
Loyola Univ. of Chicago.
222
A140 717.6
Mitochondrial Function of Cerebral Vasculature
in Insulin Resistant Zucker Obese Rats. I. Merdzo, I. Rutkai,
T. Tokes, V.N.L.R. Sure, P.V.G. Katakam, D.W. Busija. Tulane
Univ. Sch. of Med.
A141 717.7
Diminazene Aceturate Attenuates Obesity
and Promotes a Balance of the Renin-Angiotensin System in
Fat and Muscle Tissue in Young and Aged Rats on High Fat
Diet. Y. Sakarya, E. Bruce, D. Morgan, N. Tümer, C.S. Carter,
P.J. Scarpace. Univ. of Florida and VA Geriat. Res. Educ. &
Clin. Ctr.
A142 717.8
A Nutraceutical
Formulation
Improves
Cardiometabolic Parameters in Obese/Overweight Subjects. S.
Nair, Y. Hua, D.Y. Ren, Q. Wang, T.P. Rasmussen, D.T. Smith,
T.J. Robinson, R.P. Nair, M. Muhammed, N. Kalyanam. Sch.
of Pharm. and WWAMI Med. Sch., Univ. of Wyoming, Nutriwyo
LLC, Laramie and Sabinsa Corp., East Windsor, NJ.
718. CARDIOMYOCYTES/HEART FAILURE I
Poster
Exhibit Halls A-D
A145 718.1
Absence of Gravin’s Scaffolding Enhances
Myofilament Sensitivity to Calcium by Modulating Actomyosin
ATPase Activity. S. Suryavanshi, S. Singh, W.D. Gao, B.
McConnell. Univ. of Houston, Univ. of Florida and Johns
Hopkins Med.
A146 718.2
The Role of CaMKIId in Angiotensin Ii-Induced
Cardiac Inflammation and Fibrosis. A. Willeford. UCSD.
A147 718.3
Blocking Effect of Carvedilol, a Beta-Blocker
on Na+/Ca2+ Exchange Current in Isolated Cardiac Ventricular
Cells of Guinea Pig. Y. Watanabe, J. Kimura. Hamamatsu
Univ. and Fukushima Med. Univ., Japan.
A148 718.4
Carbon Monoxide Releasing Molecule-3
Alleviates Angiotensin Ii-Induced Hypertrophy and Apoptosis
by Inhibiting Oxidative and Endoplasmic Reticulum Stress in
H9c2 Cardiomyocytes. R.T. Kinobe, J. Phie, N. Haleagrahara,
L. Chilton. Col. of Publ. Hlth., Med. & Vet. Scis., James Cook
Univ., Australia.
A149 718.5
Combined Treatment of Hydrogen Sulphide
and Nitric Oxide Limit the Progression of Left Ventricular
Hypertrophy Induced by Isoprenaline– Caffeine in Wistar
Kyoto Rats. A. Ahmad, M.A. Sattar, H.A. Rathore, S.A. Khan,
M. Azam, N. Abdullah, E.J. John. Univ. Sains Malaysia,
COMSATS Inst. of Information Technol., Islamabad, Pakistan,
Univ. of Malaya and University Col. Cork, Ireland.
A150 718.6
Disruption of Gravin’s Scaffolding Protects
against Isoproterenol-Induced Heart Failure. B. McConnell,
S. Suryavanshi, F. Fa’ak, A. Diaz Diaz, S. Singh. Univ.
of Houston.
A151 718.7
Protein Expression Differences in Hypertrophic
Cardiomyopathy Transgenic Mice. M.R. Shah, R. Abraham, J.
Afzal, S. Vakarou. Howard Univ.
A152 718.8
Intralipid
Protects
against
Hypoxia/
Reoxygenation Injury in Human Coronary Artery Endothelial
Cells and Cardiomyocytes. M.M. Salzman, E.R. Warner II,
M.L. Riess. Vanderbilt Univ. Med. Ctr.
SUNDAYPHARMACOLOGY
A153 718.9
2-Methoxyestradiol
Protect
against
Isoproterenol-Induced Cellular Hypertrophy in the Human
Ventricular Cardiomyocytes, RL-14 Cells, through MAPK- and
NF-κB-Dependent Mechanisms. Z.H. Almaayah, A.O.S. ElKadi. Univ. of Alberta.
A154 718.10 Cardiomyocytes Release IFN-β in Response
to Hypoxia: A Previously Unrecognized Cardiomyocyte to
Fibroblast Signaling Pathway. C. Bangeranye, P. Wang, P.K.
Chatterjeee, J. Predmore, F. McNeil, C. Metz, E. Miller, S.
Day, S.R. Powell. Hofstra-NSLIJ Sch. of Med., Feinstein Inst.
for Med. Res., Manhasset and Univ. of Michigan Sch. of Med.
719. CARDIOVASCULAR PHARMACOLOGY I
A167 719.13 The Effect of Losartan on Marfan Syndrome
Is Angiotensin II Receptor Type 1 Independent. S. Sellers, R.
Chan, M. Mielnik, U. Jermilova, M. Pavlovic, J. Hirota, M.
Seidman, J.C. Hogg, M. Esfrandiarei, C. Van Breemen, P.
Bernatchez. Univ. of British Columbia.
A168 719.14 Burn Injury Alters Cardiac β-Adrenergic
Receptor Signaling in Interleukin 6 Knockout Mice. A.N.
Guillory, A. El Ayadi, C. Porter, D.N. Herndon, C.C. Finnerty.
Univ. of Texas Med. Branch at Galveston, Shriners Hosps.
for Children.
720. GI PHARMACOLOGY
Poster
Poster
Exhibit Halls A-D
A155 719.1
MSC Exosomes Deliver Cardioprotective miR21 K. Luther, M. McGuinness, L. Haar, H. Xu, J. Chen, M.
Medvedovic, W.K. Jones. Loyola Univ. Chicago Maywood and
Univ. of Cincinnati.
A156 719.2
Characterization of β2-Containing Receptors
in Rat Brainstem Using [125i]A-85380 M.I. Davila-Garcia, H.
Kamendi, B. Ogunlade, A. Robinson. Howard Univ.
A157 719.3
Superoxide via Sp3 but Not NF-κB Regulates
Renal AT1 Receptor Expression and Function in Human Kidney
Cells. M. Saleem, M. Asghar. Univ. of Houston Col. of Pharm.
A158 719.4
Development of a Microphysiological System
to Assess Vitamin D Metabolite Disposition in the Renal
Proximal Tubule. B.D. Chapron, A. Jaklic, B. Phillips, E.
Kelly, J. Himmelfarb, K. Thummel. Univ. of Washington.
A159 719.5
Angiotensin II Negatively Modulates Coronary
Reactive Hyperemia and Deletion of Soluble Epoxide
Hydrolase Partially Ameliorates Its Effect. A. Hanif, D.C.
Zeldin, M.A. Nayeem. West Virginia Univ. and NIEHS, NIH,
Research Triangle Park.
A160 719.6
Unexpected Negative Role of the AT1R
Adaptor Protein βarrestin1 in the ERK1/2 Activation of SHRDerived Primary Astrocytes. S. Negussie, A. Lymepropoulos,
M.A. Clark. Col. of Pharm., Nova Southeastern Univ.
A161 719.7
Effect of Ang III on JNK Mitogen Activated
Protein Kinase in Wistar Rat VSMCs. A.Z. Alanazi, M.A. Clark.
Nova Southeastern Univ.
A162 719.8
Calpain-2 Activates Akt via TGFβ1-MTORC2
Pathway in Pulmonary Artery Smooth Muscle Cells. P.K.
Abeyrathna, L. Kovacs, Y. Su. Med. Col. of Georgia -Augusta
Univ. and Charlie Norwood VA Med. Ctr.
A163 719.9
TBX20 Regulates Endothelial Angiogenesis
and Migration. S. Meng, W.T. Wong, J.P. Cooke. Houston
Methodist Res. Inst.
A164 719.10 Kruppel-Like
Factor
15:
A
Critical
Transcriptional Regulator of Hypoxia-Induced Endothelial
Arginase 2 D. Pandey, D. Hori, L. Santhanam, D. Berkowitz,
L. Romer. Johns Hopkins Univ. Sch. of Med.
A165 719.11 Biased Activation of Soluble Guanylyl
Cyclase Can Cause Contraction of Isolated Arteries. C.M.S.
Detremmerie, S.W-S. Leung, A. Xu, Y. Gao, P.M. Vanhoutte.
The Univ. of Hong Kong and Peking Univ. Hlth. Sci. Ctr.
A166 719.12 Human Perivascular Adipose Tissue Contains
an Adrenergic System. N. Ayala-Lopez, C. Pereira-Hicks, R.
Burnett, G.D. Fink, S.W. Watts. Michigan State Univ.
Exhibit Halls A-D
Translational and Clinical Pharmacology
A170 720.1
Lubiprostone Stimulates HCO3- Secretion
in Rat Stomach and Duodenum Mediated by Different EP
Receptor Subtypes. K. Takeuchi. Kyoto Pharmaceut. Univ.
A171 720.2
Attenuation of the Deleterious Course and
Gastric Lesions after Bilateral Nephrectomy in Rats, NOSystem Relation. BPC 157, L-Arginine, L-NAME. D. Drmic, M.
Sucic, A. Zenko Sever, D. Kolenc, V. Andrijasevic, J. Suran,
S. Seiwerth, P. Sikiric. Sch. of Med., Univ. of Zagreb, Univ.
Hosp. ‘Holy Spirit’, Univ. Hosp. Ctr. and Fac. of Vet. Med.,
Zagreb, Croatia.
A172 720.3
Microbiota-Derived Metabolites Associated
with Metabolic Improvements after Gastric Bypass Surgery
and Their Effects on Intestinal Cells In Vitro. M. Jennis, J.R.
Mabus, C.R. Cavanaugh, G. Leo, J. Lenhard, P.J. Hornby.
Janssen, Spring House, PA.
A173 720.4
The Effect of PAK1 Knockout on the Efficacy
of Metoclopramide in a Murine Model of Postoperative Ileus.
T. Peery, O. Rivas, D. Bhattarai, K. Uray. Univ. of Texas Med.
Sch. at Houston.
A174 720.5
Anti-inflammatory and Antioxidant Effects of
Flavonoid-Rich Fraction of Bergamot Juice in a Mouse Model
of Intestinal Ischemia/Reperfusion Injury. D. Impellizzeri,
M. Cordaro, M. Campolo, E. Esposito, S. Cuzzocrea, M.
Navarra. Univ. of Messina.
A175 720.6
Use of a Non-native Chloride Channel as a
Treatment for Interstitial Cystitis. J.M. Beckel, T.S. Tillman, P.
Tang, W.C. de Groat, Y. Xu. Univ. of Pittsburgh Sch. of Med.
A176 720.7 Amygdaloid Corticotropin Releasing Factor as
the Key Mediator of Chronic Visceral Pain in Females with a
History of Early Life Stress. D.K. Prusator, B. Greenwood-Van
Meerveld. Univ. of Oklahoma Hlth. Sci. Ctr.
A177 720.8
Enhanced Translocation of Nanoparticles
with Low Surface Coverage of Phage Display Peptide into
Rat Intestinal Mucosa. D. Myers, A. Nelson, J. Holloway, Z.
Szekely, X. Zhang, P.J. Sinko. Rutgers Univ., Piscataway.
A178 720.9
Engineering Nano-based Delivery Systems
for a Rectal Pre-exposure Prophylaxis Treatment for HIV
Prevention. A. Nelson, Z. Szekely, X. Zhang, P.J. Sinko.
Ernest Mario Sch. of Pharm., Rutgers Univ., Piscataway.
A179 720.10 Fibroblast Growth Factor 21 Deficiency
Attenuates DSS-Induced Acute Colitis through Activation of
Intestinal Epithelial Cell STAT3-Mediated Pathway. L. Liu, C.
Zhao, G. Dryden, C. McClain, W. Feng. Univ. of Louisville.
223
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PHYSIOLOGYSUNDAY
Physiology
721. MICROCIRCULATION: ANGIOGENESIS/
MICROVASCULAR REMODELING/INJURY
AND REPAIR
Poster
(Sponsored by: Microcirculatory Society)
Exhibit Halls A-D
B1
721.1
VEGF Knockdown in Muscle Improves
Recovery of Blood Flow and Arteriolargenesis after Ischaemia.
M.J.C. Machado, F. Riu, A.V. Benest, D.O. Bates. Univ. of
Nottingham, U.K.
B2
721.2
Bone Marrow-Derived Stromal Cells Improve
Microvascular Perfusion in Skin Flaps Subjected to Ischemia
Reperfusion Injury. Y-H. Tang. LSU Hlth. Sci. Ctr., Shreveport.
B3
721.3
Therapeutic Transplant Efficacy of Endothelial
Progenitor Cells Is Impaired by NK Cells. E.C. Exner, A.C.
Abel, S.C. Malarkannan, A.C. Greene. Med. Col. of Wisconsin
and Blood Ctr. of Wisconsin, Milwaukee.
B4
721.4
Adherens Junction Proteins in Cochlear Lateral
Wall Capillaries Are Altered by Loud Sound-Induced Stress to
the Ear. Q. Yu, S. Foster, S. Dziennis, T. Wilson, A.L. Nuttall.
B5
721.5
Differential Expansion of the Capillary Bed
through Physiological Angiogenesis in Skeletal Muscle. R.
Kissane, S. Egginton. Sch. of Biomed. Sci., Univ. of Leeds.
B6
721.6
Interleukin-19 Can Simultaneously Reduce
Atherosclerosis and Increase Perfusion in Hind Limb Ligated
LDLr-/- Mice. M. Ray, K. Gabunia, S. Kelemen, F. Kako, J.
Richards, M.V. Autieri. Temple Univ. Lewis Katz Sch. of Med.
B7
721.7
Angiogenesis and Expression of IGF2R, IGF2,
uPAR, and TGFB in a Rat Obesity Model. D.S. Bayless, R.D.
Sheldon, M.A. Linden, R.S. Rector, M.H. Laughlin. Univ.
B8
721.8
Maternal Hyperleptinemia Increases Arterial
Stiffening and Alters Vasodilatoy Responses to Insulin in Adult
Male Mice Offspring. F.I. Ramirez-Perez, K.A. Pennington,
K.E. Pollock, O.O. Esangbedo, C.A. Foote, C.C. ReyesAldasoro, H-H. Wu, T. Ji, L.A. Martinez-Lemus, L.C. Schulz.
Univ. of Missouri-Columbia and City Univ. London, U.K.
B9
721.9
Increased Cerebral Capillary Density in
Aquaporin-4 Knockout Mouse. K. Xu, K. Almotah, Y. Zhang,
T.S. Radford, X. Yu, W.F. Boron, J.C. LaManna. Case Western
Reserve Univ.
B10
721.10 Increased Shear Rate Drives Arteriolar
Collateral Remodeling after Acute Microocclusion but Might
Not Concern Venular Collateral Remodeling. W. Xiang, B.
Reglin, W. Rong, B. Nitzsche, M. Maibier, P. Guimarães, A.
Ruggeri, T.W. Secomb, A.R. Pries. Inst. of Physiol., Berlin,
Dept. of Info. Engin., Padova, Dept. of Physiol., Phoenix and
German Heart Inst., Berlin.
B11
721.11 Endothelial Maturity as a Function of Shear
Stress: A Novel, Non-invasive Intravital Imaging Approach.
M.R. Kelly-Goss, B. Ning, D.N. Tavakol, S. Hu, P.A. Yates,
S.M. Peirce. Univ. of Virginia.
224
B12
721.12 Serine 275 and Serine 328 in the CarboxylTerminus
Regulates
Phosphorylation-Dependent Antiproliferative Properties of Connexin 37 N.L. Jacobsen, S.
Taylor, T. Pontifex, J. Burt. Univ. of Arizona.
B13
721.13 Pericyte Recruitment in a Diabetic Mouse
Model of Corneal Neovascularization. D.N. Tavakol, M. KellyGoss, P. Yates, S. Peirce-Cottler. Univ. of Virginia.
722. MICROCIRCULATION: ATHEROSCLEROSIS/
THROMBOSIS/PLATELETS
Poster
Exhibit Halls A-D
B14
722.1
Gamma Linoleic Acid and Trans Linoleic Acid
Effects on Atherogenic Dieted Rabbit Tissue Sensitivity to
Insulin. E.L. Beard, A.N. Swafford; Jr.
Loyola Univ. New
Orleans and Our Lady of the Lake Col., Baton Rouge.
B15
722.2
Attenuation of EPA and DHA-Mediated Platelet
Inhibition Effects following Heterogeneous Agonist Treatment.
J.L. Bormann, E.S. Meyer, E.M. Voigt, S.W. Whiteheart, M.K.
Larson. Augustana Univ., SD and Univ. of Kentucky.
B16
722.3
Deficiency for Smooth Muscle-Specific InsulinLike Growth Factor I Receptor Increases Atherosclerotic
Plaque Size and Promotes Plaque Destabilization. S.
Sukhanov, Y. Higashi, P. Snarski, P. Delafontaine. Univ.
B17
722.4
Ex Vivo Validation of Intravascular Ultrasound/
Photoacoustic Tissue Characterization. A. Kole, J. Hui, Y. Cao,
P. Wang, J-X. Cheng, M. Sturek. Indiana Univ. Sch. of Med.
and Purdue Univ.
B18
722.5
Electronic Cigarettes Modulate Platelet
Inflammatory, Adhesion, Activation and Aggregation
Responses. S. Hom, T. Wang, L. Chen, W. Yin, D.A.
Rubenstein. Stony Brook Univ.
B19
722.6
Platelet Adhesion to Vascular Endothelial Cells
through PECAM-1 Regulates Endothelial Cell Inflammatory
Responses. W. Yin, D. Meza, D.A. Rubenstein. Stony
Brook Univ.
B20
722.7
Effects of SIRT3 Deficiency on Vasomotor
Function and Atherosclerotic Plaque Composition in Mice.
C.M. Roos, M.A. Hagler, B. Zhang, J.D. Miller. Mayo Clin.
B21
722.8
Electronic Cigarette Extracts Alter Endothelial
Cell Inflammatory Responses. K.E. Barber, W. Yin, D.A.
Rubenstein. Stony Brook Univ.
B22
722.9
Multicolor Two-Photon Intravital Microscopy
Reveals Monocyte Patrolling and Macrophage Migration in
Atherosclerosis. S. McArdle, N. Ray, K. Ley. La Jolla Inst. for
Allergy and Immunol. and Univ. of Alberta.
B23
722.10 Glycated Albumin Alters Platelet Activities
Associated with Cardiovascular Diseases. I. Soaita, W. Yin,
D.A. Rubenstein. Stony Brook Univ.
B24
722.11 In Vivo Imaging of Infection-Induced
Cogulopathy in the Microcirculation. C.N. Jenne, R.P.
Davis, B. McDonald. Univ. of Calgary, Canada and Univ. of
British Columbia.
SUNDAYPHYSIOLOGY
723. MICROCIRCULATION: INFLAMMATION/
LEUKOCYTE-ENDOTHELIUM INTERACTIONS
724. MICROCIRCULATION: INSTRUMENTATION,
METHODOLOGY AND EXPERIMENTAL MODELS
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
B25
723.1
Stroke Severity in Obesity: Role of Leukocyte
Activation and Vascular Dysfunction. S. Asano, H. Hu, X.
Ren, K. Lemaster, G. O’Connell, T. Barr, J.C. Frisbee, P.D.
Chantler. West Virginia Univ. Hlth. Sci. Ctr.
B26
723.2
The Role of NADPH Oxidase Isoform 1 in
L-NAME-Induced Leukocyte-Endothelial Interactions in Rat
Mesenteric Postcapillary Venules. A. Zabrecky, H. Pham, A.
Koon, B. Rueter, R. Barsotti, L. Young, Q. Chen. Philadelphia
Col. of Osteo. Med.
B27
723.3
Molecular Mechanism of Tethers and Slings in
CD4+ T Cells. M. Abadier, K. Ley. La Jolla Inst.
B28
723.4
Hypertensive Mechanical Stretch: A Model for
Monocyte-Derived Dendritic Cell Differentiation. R. Loperena,
W. Chen, A. Kirabo, D.G. Harrison. Vanderbilt Univ. Med. Ctr.
B29
723.5
A New Carbon Monoxide-Releasing Molecule
(CORM401) Suppresses PMN Migratory Potential through an
F-Actin-Dependent Mechanism. K. Inoue, E. Patterson, K.
Chung, R.F. Potter, A. Capretta, D.D. Fraser, G. Cepinskas.
Ctr. for Critical Illness Res., London, ON and McMaster
Univ., Canada.
B30
723.6
The Effect of Splenectomy on the Recruitment
of Inflammatory Cells in the Cerebral Microvasculature.
H. Seifert, J. Russell, D.N. Granger. LSU Hlth. Sci.
Ctr. Shreveport.
B31
723.7
Circulating Microparticles in Pancreatic Tumor
Patients and Their Roles in Mediating Leukocyte Adhesion in
Intact Microvessels. M. Zhou, S. Xu, Q. Feng, J. Wong, P. He.
Penn State Col. of Med.
B32
723.8
Effect of High Fat Feeding on Inflammatory
Cytokines in Obese and Healthy Children. A.S. Chiu, G.
Ganesan, P. Horvath, G. Bachman, F.P. Zaldivar, P.R.
Galassetti. Univ. of California, Irvine.
B33
723.9
Stimulation of Mitochondrial Fragmentation
and Mitophagy by TNFα in Microvascular Endothelial Cells.
T. Kalogeris, R. Korthuis. Univ. of Missouri-Columbia and
Dalton Cardiovasc. Res. Ctr.
B34
723.10 Pretreated with Evans Blue Can Prevent Mast
Cell Degranulation and Compound 48/80-Induced Anaphylaxis.
Y-T. Chen, S-Y. Lin, S-I. Lue, T-S. Lu, Y-S. Fu. Kaohsiung
Med. Univ., Taiwan, Brigham and Women’s Hosp. and Harvard
Med. Sch.
B35
723.11 Reduced Endothelial Basal Nitric Oxide Induces
Leukocyte Adhesion through Src-Dependent Phosphorylation
of Constitutive Intercellular Adhesion Molecule-1 B. LuckeWold, A. Logsdon, X. Li, S. Xu, X. Lichong, C. Siedlecki, J.
Huber, C. Rosen, P. He. West Virginia Univ. Sch. of Med. and
B36
723.12 Three-Dimensional Monolayer Stresses of
Neutrophil Diapedesis. Y-T. Yeh, R. Serrano, Y-S. Li, J.C. del
Alamo, S. Chien, J.C. Lasheras. UCSD.
B37
724.1
Validation of the Doubly Labeled Water
Method Using Integrated Cavity Output Spectroscopy against
Isotope Ratio Mass Spectrometry and Whole-Room Indirect
Calorimetry. E.L. Melanson, G. Plasqui, L. Wouters, W.S.
Kohrt, T. Swibas, V.A. Catenacci, J.R. Speakman, E.S.
Berman. Univ. of Colorado Anschutz Med. Campus, Maastricht
Univ. Med. Ctr., Netherlands, Aberdeen Univ., U.K. and Los
Gatos Res., Mountain View, CA.
B38
724.2
Experimental Approaches for Studying Cell
Water and Volume Regulation in Apoptotic Cells. M.A. Model.
Kent State Univ.
B39
724.3
An Experimentally-Derived Wall Shear Rate
Equation for Use in Microvascular Preparations. D. Goldman,
B.K. Al-Khazraji, D.N. Jackson. Univ. of Western Ontario.
B40
724.4
Circulating Microparticles in Pancreatic
Cancer Patients and Their Interactions with Endothelial Cells
of Engineered Microvessel Network. X. Li, M. Zhou, J. Wong,
P. He. Penn State Col. of Med.
B41
724.5
The Effect of Media Type on Nerve Presence
in Cultured Microvascular Networks. N.A. Hodges, R.W. Barr,
W.L. Murfee. Tulane Univ.
B42
724.6
Barometric Calibration of Luminescent Oxygen
Probes. A. Golub, R. Pittman. Virginia Commonwealth Univ.
725. MICROCIRCULATION: ISCHEMIAREPERFUSION/FREE RADICAL BIOLOGY
Poster
Exhibit Halls A-D
B43
725.1
Delayed β1 Adrenergic Receptor Blockade
Attenuates Cardiac Oxidative Stress, Remodeling, and
Improves Cardiac Function in Post-myocardial Infarction.
W. Bao, J. Kuziw, A. Zacco, M. Ringenberg, C.
Schnackenberg. GlaxoSmithKline.
B44
725.2
Soluble Guanylate Cyclase Activation during
Ischemic Injury in Mice Protects against Post-ischemic
Inflammation at the Mitochondrial Level. D. Wang, A. Jones,
W. Wang, M. Wang, R. Korthuis. Univ. of Missouri and Rock
Bridge H.S., Columbia.
B45
725.3
Caveolin-3 Plays a Critical Role in Autophagy
after Ischemia Reperfusion. A. Kassan, U.N. Pham, E.
Cho, Q.M. Nguyen, P.P. Patel, D.M. Roth, B.P. Head, H.H.
Patel. UCSD.
B46
725.4
Administration of Metformin during Early
Reperfusion Decreases Cardiac Injury through Inhibition of
MPTP Opening. E. Lesnefsky, J. Thompson, Y. Hu, Q. Chen.
Virginia Commonwealth Univ. and McGuire VA Med. Ctr.
225
S
U
N
PHYSIOLOGYSUNDAY
B47
725.5
Novel Finding of Mitochondrial Biogenesis
during Cardiac Surgery: Marker or Mediator of Ischemia/
Reperfusion Injury, or an Element of the Homeostatic
Intracellular Repair Response (HIR2) A. Andres, D.
Sengstock, S. Jahania, R. Dabir, K. Tucker, R. Gottlieb, R.
Mentzer. Cedars-Sinai Med. Ctr. and Beaumont Hlth. Syst.,
Dearborn, MD.
726. MICROCIRCULATION: LYMPHATIC AND
VENULAR FUNCTION
Poster
Exhibit Halls A-D
B48
726.1
Bacterial Metabolite Indole Alters Inflammatory
Signaling Cascades in Human Lymphatic Endothelial Cells.
T. Muthuchamy, Y. Lee, A. Jayaraman, R.C. Alaniz, S.
Chakraborty. Texas A&M Univ. Hlth. Sci. Ctr. and Texas A&M
Univ.
B49
726.2
Sigma Receptor Agonism by Afobazole
Attenuates Lymphatic Pumping in Juvenile Rat Mesenteric
Collecting Vessels. A.N. Trujillo, S.P. Adderly, C.P. Katnik, J.
Cuevas, J.W. Breslin. Univ. of South Florida.
B50
726.3
The
Ca2+-Activated
ClChannel
TMEM16A(ANO1) Modulates, but Is Not Required for,
Pacemaking in Mouse Lymphatic Vessels. P. Gui, S. Zawieja,
M. Li, S. Bulley, J. Jaggar, J. Rock, M. Davis. Univ. of MissouriColumbia, Univ. of Tennessee Hlth. Sci. Ctr. and UCSF.
B51
726.4
Multi-scale Modeling of Collecting Lymphatic
Vessels: From Ion Channel Activity to Lymph Transport. A.
Moshkforoush, A. Kapela, N. Tsoukias. Florida Intl. Univ.
B52
726.5
Impact of Dynamic Transmural Pressure on
Lymph Propulsion in Lymphatic Vessels. S. Jamalian, M.J.
Davis, D.C. Zawieja, J.E. Moore; Jr. Imperial Col. London,
Univ. of Missouri Sch. of Med. and Texas A&M Univ. Hlth.
Sci. Ctr.
B53
726.6
Mast
Cells-Dependent
Compromised
Response of Aged Mesenteric Lymphatic Vessels and
Surrounding Tissues to the Acute Inflammatory Challenge.
H. Skoog, G.F. Dusio, R. Tobin, D.C. Zawieja, M.K. NewellRogers, A.A. Gashev, I. Tsoy Nizamutdinova. Texas A&M
Univ. Hlth. Sci. Ctr. Col. of Med. and Baylor Scott & White Hlth.,
Temple, TX.
B54
726.7
A Novel Mouse Model of Inducible
Lymphangiogenesis through Controlled Local Expression
of VEGF-D. J.M. Rutkowski. Texas A&M Hlth. Sci. Ctr.,
College Station.
B55
726.8
Morphometric Analyses of Longitudinal and
Circular Smooth Muscle and Lacteals of the Small Intestine of
Zucker Lean and Obese Rats. A.R. Burgess, A.N. Trujillo, M.
Barter, J.W. Breslin. Univ. of South Florida.
B56
726.9
Mathematical Model of Calcium and Electrical
Dynamics in Lymphatic Endothelium. M. Jafarnejad, E.J.
Behringer, J.P. Scallan, M.J. Davis, S.S. Segal, J.E.
Moore. Imperial Col. London, Loma Linda Univ. and Univ.
B57
726.10 Lymphatic Endothelial Cell Response to X-Ray
Irradiation. A. Narayanan, J. Ford, D. Zawieja. Texas A&M
Univ. Hlth. Sci. Ctr., Temple and Texas A&M Univ.
226
B58
726.11 A Lymphedema-Inducing Mutation of Cx47,
R259C, Alters Growth Pattern and Cx43 Processing in Rat
Insulinoma Cells. J. Kanady, T. Pontifex, S-S. Taylor, A.
Simon, J. Burt. Univ. of Arizona.
727. MICROCIRCULATION: MICROVASCULAR CELL
SIGNALING PATHWAYS
Poster
Exhibit Halls A-D
B59
727.1
MicroRNA-204, SIRTUIN1, and Caveolin-1
Regulate Vascular Endoplasmic Reticulum Stress and
Endothelium-Dependent Vasorelaxation. M. Kassan, A.
Vikram, Q. Li, Y-R. Kim, S. Kumar, J. Jacobs, K. Irani. Univ.
of Iowa.
B60
727.2
Macrophages Drive Microvascular Dysfunction
in Obesity by Depleting Vessel Hydrogen Sulfide. J.J. Candela,
C. White. Rosalind Franklin Univ. of Med. and Sci.
B61
727.3
Mitochondria Modulates Calcium Pulsars
Kinetics in Native Endothelial Cells from Mouse Mesenteric
Arteries. F. Toussaint, D. Béziau, C. Charbel, A. Blanchette,
G. Mayer, J. Ledoux. Montreal Heart Inst. and Univ. of Montreal.
B62
727.4
Inhibition of Inward-Rectifier K+ Channels
in Vascular Smooth Muscle Restores Myogenic Tone
Development in Mouse Bladder Arterioles. N.R. Tykocki, T.J.
Heppner, M.T. Nelson. Univ. of Vermont.
B63
727.5
Oxygen Considerations in the Design of
Microfluidics for Studying Oxygen-Dependent ATP Release
from Erythrocytes. R.J. Sove, D. Goldman, G.M. Fraser, C.G.
Ellis. Western Univ., Canada.
B64
727.6
Endothelial Nitric Oxide Synthase Protein
Distribution in Endothelial Cells along the Coronary Vascular
Tree. J.H. Israel, J.F. Bray, A.L. McIntosh, F. Schroeder, C.L.
Heaps. Texas A&M Univ.
B65
727.7
Differential Role of PKA/MLCP Axis in ATPand Adenosine-Induced Microvascular Endothelial Barrier
Enhancement. R.K. Batori, S. Kumar, A. Kasa, A.D. Verin.
Georgia Regents Univ.
B66
727.8
PDE6 Isoforms Are Expressed in Native
Endothelium but Not in Cultured Cell Lines. A. Blanchette, F.
El Jetlawi, F. Toussaint, C. Charbel, P. Comtois, J. Ledoux.
Montreal Heart Inst. and Univ. of Montréal.
B67
727.9
Lipid Composition of the Myoendothelial
Junction Allows for Compartmentalized eNOS Function. L.
Biwer, E. Taddeo, K. Hoehn, A. Straub, B. Isakson. Univ. of
Virginia and Univ. of Pittsburgh.
SUNDAYPHYSIOLOGY
728. MICROCIRCULATION: MICROVASCULAR
DEVELOPMENT AND AGING
Poster
Exhibit Halls A-D
B68
728.1
Exercise Training Attenuates Vascular Smooth
Muscle Remodeling of Coronary Microvasculature in Aged
Heart. K. Hotta, B. Chen, B.J. Behnke, P. Ghosh, D. Alarcon,
H. Morgan, M. Cowan, T. Lucero, J. Maraj, A. Haynes, J.N.
Stabley, M.D. Delp, J.M. Muller-Delp. Florida State Univ. Col.
of Med., Univ. of Florida Col. of Med., Kansas State Univ. Col.
of Human Ecol., Florida State Univ. Col. of Human Sci. and
Univ. of Texas Southwestern Med. Ctr.
B69
728.2
Whole
Brain
Irradiation
Impairs
Cerebromicrovascular Function and Promotes Cognitive
Decline: Potential Role of Endothelial Senescence. A.
Yabluchanskiy, P. Hertelendy, N.M. Ashpole, S. Tarantini,
S. Logan, D.B. Owen, J.A. Farley, Z. Ungvari, W.E. Sonntag,
A. Csiszar. Univ. of Oklahoma Hlth. Sci. Ctr. and Univ. of
Szeged, Hungary.
B70
728.3
IGF-1 Deficiency Exacerbates HypertensionInduced Cerebromicrovascular Rarefaction in Mice:
Implications for Cognitive Decline. S. Tarantini, C. Giles,
P. Toth, N.M. Ashpole, Z. Tucsek, M.N. Valcarcel-Ares, T.
Gautam, W.E. Sonntag, J.D. Wren, A. Csiszar, Z. Ungvari.
Univ. of Oklahoma Hlth. Sci. Ctr., Oklahoma Med. Res. Fndn.
and Univ. of Pecs, Hungary.
B71
728.4
Changes in miRNA Expression Patterns and
Vascular Aging Phenotypes in Mice with Developmental LiverSpecific Knockdown of IGF-1 S. Tarantini, C.B. Giles, J.D.
Wren, N.M. Ashpole, M.N. Valcarcel-Ares, Z. Tucsek, W.E.
Sonntag, A. Csiszar, Z. Ungvari. Univ. of Oklahoma Hlth. Sci.
Ctr. and Oklahoma Med. Res. Fndn.
B72
728.5
Loss of Bioavailable NO with Enhanced iNOS
Expression and Oxidative Stress Increase Pulmonary Arteriolar
Tone in Aged Mice. R. Drinovac, R. Jagadapillai, E. Gozal,
X. Lin, R. Vaishnav, R.P. Friedland, A.M. Roberts. Univ. of
Louisville Sch. of Med.
B73
728.6
Hypertension-Induced Impairment in Synaptic
Plasticity and Dysregulation of Genes Involved in Synaptic
Function in the Mouse Hippocampus: Implications for the
Pathogenesis of Vascular Cognitive Impairment in Aging. M.N.
Valcarcel-Ares, Z. Tucsek, S. Tarantini, P. Hertelendy, C.B.
Giles, A. Orock, W.E. Sonntag, J.D. Wren, A. Csiszar, F.
Deak, Z. Ungvari. Univ. of Oklahoma Hlth. Sci. Ctr., Fac. of
Med. and Fac. of Sci. and Informat., Univ. of Szeged, Hungary
and Oklahoma Med. Res. Fndn.
B74
728.7
Nrf2 Deficiency Exacerbates Obesity-Induced
Neurovascular Uncoupling in Mice, Mimicking the Aging
Phenotype. P. Hertelendy, M.N. Valcarcel-Ares, S. Tarantini,
Z. Tucsek, T. Gautam, E. Farkas, Z. Ungvari, A. Csiszar. Univ.
of Szeged, Hungary and Univ. of Oklahoma Hlth. Sci. Ctr.
729. MICROCIRCULATION I
Poster
Exhibit Halls A-D
B75
729.1
Western
Diet
Increases
Inflammatory
Responses and Atherosclerosis Progression via IGF-1
Receptor in ApoE-Deficient Mice. M. Wang, Y. Higashi, D.
Wang, R. Korthuis, P. Delafontaine. Univ. of Missouri and
Rock Bridge H.S., Columbia, MO.
B76
729.2
Cutaneous Thermal Injury Increases Vascular
Permeability of Rat Mesenteric Venules by a Reactive OxidantDependent Mechanism. D.M. Pfitzinger, J.M. Howard, M.
Moncure, J. Wood. Univ. of Kansas Med. Ctr.
B77
729.3
Inhibition of Epidermal Growth Factor Receptor
Tyrosine Kinase and Endoplasmic Reticulum Stress Protects
Myocardial from Ischemia - Reperfusion Injury in Type 2
Diabetic Mice. V.R. Mali, M. Ali, S. Haddox, K. Matrougui, S.
Belmadani. Eastern Virginia Med. Sch.
B78
729.4
Enterococcus faecium Strain R30 Prevents
Capillary Regression through Increasing Red Blood Cell
Velocity in Rat Soleus Muscle under Disuse Condition. Y.
Hirayama, R. Nakanishi, M. Ueno, M. Yoshikawa, A. Tategaki,
N. Maeshige, H. Fujino. Kobe Univ. and Kaneka Corp., Japan.
B79
729.5
Orphan Nuclear Receptors Nur77 and Nor1
Are Novel Regulators of Thrombotic Function in Vascular
Endothelial Cells. X. Wei, P. Yang, J. Zhang, B. Yi, G. Zhang,
L. Yin, J. Sun. Thomas Jefferson Univ. and Xinhua Hosp.,
Shanghai Jiaotong Univ.
B80
729.6
Decreased Large Conduit Artery Nitric Oxide
Bioavailability in Metabolic Syndrome Effects Peripheral
Microvessel Reactivity. K. Branyan, E. DeVallance, K.
Lemaster, R. Skinner, S. Brooks, S. Asano, J. Willimas, J.
Frisbee, P. Chantler. West Virginia Univ.
B81
729.7
Limb-Specific Differences in Vasomotion
Response to Varying Rates of Local Heating. A.T. Del Pozzi,
J.T. Miller, G.J. Hodges. Sch. of Kinesiol., Ball State Univ.,
Univ. of Alabama and Brock Univ., Canada.
B82
729.8
Process of Cell-Free Layer Formation after
Arteriolar Bifurcation and Its Physiological Effects. S. Kim, Y.C.
Ng. Natl. Univ. of Singapore.
B83
729.9
Ossified Bone Marrow Blood Vessels,
Trabecular and Cortical Bone Properties and Hematological
Parameters in 6- and 18-Month-Old Fischer 344 Rats. S.
Guderian, S. Lee, M.A. McLane, R. Prisby. Univ. of Delaware.
730. WIGGERS AWARD FEATURED TOPIC POSTERS
Poster
Exhibit Halls A-D
B84
730.1
A Splice Variant of Smooth Muscle Myosin
Phosphatase Regulatory Subunit Tunes Arterial Reactivity
and Suppresses Response to Salt Loading. J. Reho, D.
Kenchegowda, L.D. Asico, S. Fisher. Univ. of Maryland Sch.
of Med.
227
S
U
N
PHYSIOLOGYSUNDAY
B85
730.2
p66 Shc Contributes to Susceptibility to
Cerebrovascular Injury and Intracerebral Hemorrhages.
A.M. Beyer, K. Ait-Aissa, B. Miller, A. Sorokin. Med. Col.
of Wisconsin.
B86
730.3
Coronary Microvascular Smooth MuscleEndothelial Cell Communication and Notch 3 Signaling in Type
2 Diabetes. P.E. McCallinhart, O.E. Clark, M. Kanai, B. Lilly,
A.J. Trask. Nationwide Children’s Hosp. and The Ohio State
Univ. Col. of Med.
B87
730.4
Effect of Age and High Fat Diet on the Proatherogenic Response to Oscillatory Blood Flow. A.E. Walker,
S.R. Breevoort, J.R. Durrant, D.R. Machin, P.S. Dobson, E.I.
Nielson, A.J. Donato, L.A. Lesniewski. Univ. of Utah, North
Carolina State Univ. and VA Med. Ctr., Salt Lake City.
731. BLOOD PRESSURE REGULATION I
Poster
Exhibit Halls A-D
B88
731.1
Spectral Analysis Measured in Cooling-Evoked
Hemodynamic Perturbations of Rats Indicates Endogenous
Nitric Oxide Facilitating Sympathomyogenic Oscillations. C-S.
Tung, Y-P. Liu, Y-H. Lin, Y-C. Lin, P-L. Lee. Cheng Hsin Gen.
Hosp. and Natl. Defense Med. Ctr., Taipei and Natl. Central
Univ., Taiwan.
B89
731.2
Sympathetic Modulation Decreases in Rats
with Renovascular Hypertension Treated with Chronic
Administration of Catalase Inhibitor. M.R. Lauar, L.A. De
Luca; Jr., P.M. De Paula, D.S.A. Colombari, E. Colombari,
C.A.F. Andrade, J.V. Menani. Dent. Sch., São Paulo State
Univ., Araraquara.
B90
731.3
Sympathetic Vasomotor Activation to Different
Targets in a Model of Hypertension Induced by Nitric Oxide
Synthase Blockade. L.I. Zambrano, R.B. Pontes, M.L. Garcia,
E.E. Nishi, R.R. Campos, C.T. Bergamaschi. UNIFESP, Brazil
and UNAH, Honduras.
B91
731.4
Neuromodulation of Cranial Nerves for
Migraine and Trigeminal Neuropathy Pain: Cardiac Effects.
C.R. White, D. Snodgrass, M. Yazdizadeh, F. Yan-Go, J. Jen,
R.K. Harper, E.K. Sauerland, R.M. Harper. UCLA and Univ. of
Nevada, Reno.
B92
731.5
Differential Effects of Group III/IV Skeletal
Muscle Afferents and Hypoxia on Blood Pressure during LowerExtremity Dynamic Exercise. D.P. Chantigian, A.L. Cowl, B.D.
Johnson, M. Keller-Ross, T.P. Olson. Univ. of Minnesota,
Minneapolis and Mayo Clin.
B93
731.6
Estrogen Does Not Protect Ovariectomized
Mice from Increased Blood Pressure and Sodium Retention
Induced by High Fructose and High Salt Diet. L. Fan, S. Saberi,
A. Dehghani, C. Watauruocha, L. Kudo, A. Rouch. Oklahoma
State Univ. Ctr. for Hlth. Sci.
B94
731.7
Effects of Acute Dietary Polyphenols
Supplementation on Hemodynamic Responses to Dynamic
Exercise in Young Prehypertensive Men. H-M. Choi, K-A. Kim,
H-W. Doh, H. Nho, S-K. Park, S-W. Yang, J-K. Kim. KyungHee
Univ., South Korea.
228
B95
731.8
Autonomic Dysreflexia Persists following Acute
Rehabilitation in Rats with Incomplete Contusive Spinal Cord
Injury. K.A. Harman, K.M. DeVeau, J.W. Squair, C.R. West,
D.S.K. Magnuson, A.V. Krassioukov. Univ. of Louisville and
Univ. of British Columbia.
B96
731.9
Relationship between the Elevated Orexin
Sensitivity via OX2R in RVLM and an Increased Arterial
Pressure in Rats Fed a High Fat Diet. A. Yamaguchi, K.
Obata, H. Morita. Sch. of Med. and Grad. Sch. of Med.., Gifu
Univ., Japan.
732. CARDIAC FUNCTION AND DYNAMICS
Poster
Exhibit Halls A-D
B97
732.1
Myocardium from the Left and Right Ventricles
of Human Hearts Have Similar Mechanical Properties.
C.A. Blair, M. Guglin, A. Stromberg, K.S. Campbell. Univ.
of Kentucky.
B98
732.2
Dioscin Improves Heart Function by Increasing
Sodium Influx via NCX in Rat Cardiomyocytes. Y. Yin, T. Cong,
F. Yang, Y. Han, K. Wen, Y. Kang, J. Lou. Tianjin Med. Univ.,
China and Thomas Jefferson Univ.
B99
732.3
Single-Beat
Estimation
of
Isovolumic
Maximum Pressure Can Predict Left Ventricular Contractility in
Rats. T. Tohyama, K. Saku, T. Nishikawa, Y. Oga, T. Kishi, K.
Sunagawa. Kyushu Univ., Japan.
B100 732.4
Mitigation of Diazinon-Induced Cardiovascular
and Renal Dysfunction by Gallic Acid. T. Ajibade, A.A.
Oyagbemi, T.O. Omobowale, E.R. Olowu. Univ. of
Ibadan, Nigeria.
B101 732.5
The Long Acting GLP-1 Receptor Agonist,
Liraglutide, Augments Myocardial Contractile Responses and
Cardiac Efficiency under Sympathetic Stimulation in Obesity
and Myocardial Infarction. A.G. Goodwill, D.J. Sassoon, J.N.
Noblet, A.M. Conteh, K.J. Mather, J.D. Tune. Indiana Univ.
Sch. of Med.
B102 732.6
Medical Device Materials and Blood Pressure
Alterations in Mice. A. Swiercz, M. Sherman, N. Muselimyan,
L. Swift, P. Marvar, N.G. Posnack. George Washington Univ.
B103 732.7
A Support Vector Machine to Predict Impending
Pre-syncope from Hemodynamic-Derived Signals during
Progressive Central Hypovolemia. J.P. van der Ster, F.C.
Bennis, W.J. Stok, B.E. Westerhof, J.J. Settels, F. Hatib, J.J.
van Lieshout. Acad. Med. Ctr., Amsterdam, Univ. of Twente,
Netherlands, Edwards Lifesci. BMEYE, Amsterdam, Edwards
Lifesci., Irvine, CA and Queen’s Med. Ctr., Nottingham.
B104 732.8
Low-Dose Triiodo-L-Thyronine Treatment
Prevents Decline in Cardiac Function and Arrhythmia
Inducibility Resulting from Severe Calorie Restriction. C.
Costello, V. Rajagopalan, Y. Zhang, E. Schultz, A. Thawani,
A.M. Gerdes. NYIT Col. of Osteo. Med.
B105 732.9
Positive and Negative Inotropic Effects of
Left Ventricular Mechano-energetics in Hypothermic and
Hyperthermic Rat Hearts. K. Obata, H. Morita, M. Takaki. Giful
Univ. Grad. Sch. of Med., Japan.
SUNDAYPHYSIOLOGY
B106 732.10 Hemodynamic Effects of Enalapril and
B-Type Natriuretic Peptide on the Progression of PacingInduced Cardiac Myopathy in Conscious Dogs. K. Qanud,
N. Shnayderman, M. Ochoa, X. Xu, T. Hintze. New York
Med. Col.
B107 732.11 Over-Expression of Osteopontin Significantly
Increases Cardiomyoycte Size. M. McBride, L. Downie, T.
Martin, J.D. McClure, S. Nicklin, D. Graham. Univ. of Glasgow.
B108 732.12 Smyd5 Regulates Hypertrophic Growth in the
Heart. A. Anderson, M. Miller, L. Wang, S. Franklin. Univ.
of Utah.
733. CORONARY CIRCULATION
Poster
Exhibit Halls A-D
B109 733.1
Role of Leptin in Coronary Vascular Dysfunction
and Proliferation. J.N. Noblet, A.G. Goodwill, D.J. Sassoon,
A.M. Kiel, J.D. Tune. Indiana Univ. Sch. of Med. and Purdue
Univ. Weldon Sch. of Biomed. Engin.
B110 733.2
Coronary Blood Flow Velocity Responses
to Oxygen and Carbon Dioxide in Humans. L.M. Boulet, M.
Stembridge, M.M. Tymko, J.C. Tremblay, G.E. Foster. Sch. of
Hlh. and Exer. Sci., Univ. of Briish Columbia and Cardiff Sch. of
Sport, Cardiff Metro. Univ., U.K.
B111 733.3
Kv1 Channels Are Critical Regulators of
Coronary Blood Flow in Swine. A.G. Goodwill, J.N. Noblet,
D.J. Sassoon, L. Fu, L. Schepers, J. Sturek, J.D. Tune, G.M.
Dick. Indiana Univ. Sch. of Med. and California Med. Innovation
Inst., San Diego.
B112 733.4
Propofol Dialates Coronary Arteries In Vitro
via Endothelial TRPA1 and TRPV1 Channels. P. Sinha Roy,
I. Bratz, D. Damron. Kent State Univ. and Northeast Ohio
Med. Univ.
B113 733.5
Coronary Flow and Cardiac Responses to
Adenosine in Beta-1 Adrenergic Knockout Mice. B. Teng, S.J.
Mustafa. West Virginia Univ.
B114 733.6
Determinants of Myocardial Oxygen Delivery in
Response to Moderate and Severe Reductions in Hematocrit.
A.M. Kiel, A.G. Goodwill, J.N. Noblet, D.J. Sassoon, J.D.
Tune. Indiana Univ. Sch. of Med. and Weldon Sch. of Biomed.
Engin., Purdue Univ.
B115 733.7
Improvement of Coronary Flow and Cardiac
Function, as a Function of Deletion/Downregulation of Soluble
Epoxide Sydrolase. J. Qin, S. Kandhi, G. Froogh, H. Jiang, D.
Sun, A. Huang. New York Med. Col.
B116 733.8
Aging Down Regulates L-Type Voltage-Gated
Calcium Channels in Resistance Coronary Arteries. F.A.
Mansour, M.O. Hassan, A.A. Khan, S. Albarwani. Col. of
Med. and Hlth. Sci., Sultan Qaboos Univ., Oman.
B117 733.9
SERCA
Inhibition
Attenuates
Medial
Thickening in an Organ Culture Model of Coronary Artery
Disease. S.D. Rodenbeck, A.L. Barnard, M. Sturek. Indiana
Univ. Sch. of Med.
B118 733.10 Osteoprotegerin and Receptor Activator of
Nuclear Factor-κB Ligand Alter Intracellular Ca2+ Handling in
Coronary Smooth Muscle Cells in an In Vitro Model of Coronary
Artery Calcification. J.K. Badin, M. Sturek. Indiana Univ. Sch.
of Med.
734. DIABETES AND INSULIN RESISTANCE I
Poster
Exhibit Halls A-D
B119 734.1
CTPR3 Prevents ETOH- Induced Hepatocyte
Apoptosis. S. Dunlay, J.M. Peterson. East Tennessee State
Univ. and East Tennessee Univ.
B120 734.2
Only Two Weeks of Physical Inactivity Induces
Insulin Resistance and Impairs Glycemic Control in Older
Adults. C. McGlory, M. von Allmen, T. Stokes, S. Phillips.
McMaster Univ., Canada.
B121 734.3
Loss of Pancreatic Mig6 Improves Glucose
Homeostasis during Diet-Induced Obesity. N. Olivos, P.T.
Fueger. Indiana Univ. Sch. of Med.
B122 734.4
HMGB1 Mediates Sidestream Cigarette
Smoke-Induced Metabolic Disruption. O.J. Taylor, M.E. Porter,
P.R. Reynolds, B.T. Bikman. Brigham Young Univ.
B123 734.5
Placental Growth Factor Expression Is
Inhibited by Hyperglycemia in Cardiac Cells. F. Rouf, P.G.
Lloyd. Oklahoma State Univ.
B124 734.6
Attenuated
Response
of
hCD39
Overexpressing Transgenic Mice to High-Fat Diet-Induced
Obesity and Glucose Intolerance. A.U. Brandes, Y. Zhang,
S.C. Robson, B.K. Kishore. Univ. of Utah, VA Med. Ctr.,
Salt Lake City, Beth Israel Deaconess Med. Ctr. and Harvard
Univ., Boston.
B125 734.7
Muscarinic Agonist Carbachol Restores Insulin
Secretion and Abolishes Type 2 Diabetes-Like Condition in
Wolframin1 Deficient Mice in Glucose Tolerance Test. M.
Loomets, R. Reimets, M. Plaas, E. Vasar. Tartu Univ., Estonia.
B126 734.8
Production of Soluble Receptor for Advanced
Glycation End-Products following Acute Aerobic Exercise Is
Gender Specific. E.R. Miranda, J.T. Mey, B.K. Blackburn, S.S.
Farabi, L. Quinn, J.M. Haus. Univ. of Illinois at Chicago.
B127 734.9
Female Farm Workers at Higher Risk for the
Metabolic Syndrome and Insulin Resistance, Western Cape
Province, South Africa. M.J. Kruger, T.A. Nell. Stellenbosch
Univ., South Africa.
B128 734.10 Effects of NOX-1 on Real-Time Blood Nitric
Oxide and Hydrogen Peroxide in Acute Hyperglycemia. A.E.
Mawhinney, M. Bertolet, M. Minni, R. Barsotti, L. Young, Q.
Chen. Philadelphia Col. of Osteo. Med.
735. HEART FAILURE I
Poster
Exhibit Halls A-D
B129 735.1
Caveolin-3 Expression Is Increased in
Anthracycline-Induced Heart Failure in Rabbits. Y. Ichikawa,
A. Zemlic-Harpf, K.H. Hammond, D.M. McKirnan, H.H. Patel,
D.M. Roth. VA San Diego Hlth. Care Syst., UCSD.
229
S
U
N
PHYSIOLOGYSUNDAY
B130 735.2
Loss of the Mitochondrial Sodium/Calcium
Exchanger in the Adult Heart Causes Sudden Death and
Overexpression Protects against Heart Failure. T.S. Luongo,
M. Nwokedi, J.P. Lambert, D. Kolmetzky, E. Gao, A.C.
Carpenter, J. Song, X. Chen, V.V. Patel, M. Madesh, J.D.
Molkentin, J.W. Elrod. Temple Univ. Sch. of Med. and HHMI,
Univ. of Cincinnati and Cincinnati Children’s Hosp. Med. Ctr.
B131 735.3
Daunorubicin-Induced Heart Failure Elevates
Hippocampal TNF-α and Caveolin-1 in Rabbits. Z. Zhang, B.
Alas, A. Zemljic-Harpf, Y. Ichikawa, M.D. MicKirnan, H.K.
Hammond, H.H. Patel, D.M. Roth, B.P. Head. UCSD and VA
San Diego Healthcare Syst.
B132 735.4
N-Acetylcysteine
Reverses
Established
Cardiac and Renal Fibrosis in a Mouse Model of Heart Failure.
N. Rajapakse, B. Giam, P-Y. Chu, H. Kiriazis, X-J. Du, D.M.
Kaye. Baker IDI Heart and Diabetes Inst., Melbourne.
B133 735.5
The Impact of Acute Oral Tetrahydrobiopterin
on Vascular Function in Heart Failure Patients with Reduced
Ejection Fraction. H.L. Clifton, R.S. Garten, J.F. Lee,
M.J. Rossman, J.R. Gifford, J.R. Hyden, J. Stehlik, R.S.
Richardson, D.W. Wray. VA Salt Lake City Hlth. Care Syst.,
Univ. of Utah, Virginia Commonwealth Univ. and Univ. of
Colorado Boulder.
B134 735.6
α1A-Subtype Adrenergic Therapy Is Beneficial
for Failing Right Ventricle. P.M. Cowley, G. Wang, S. Joshi,
D.H. Lovett, P.C. Simpson, A.J. Baker. San Francisco VA
Hlth. Care Syst. and UCSF.
B135 735.7
Doxorubicin May Damage Cardiomyocytes
More Than Cardiac Progenitor Cells. J. Edwards, M. Mitry, D.
Laurent. New York Med. Col.
B136 735.8
DCD Donor Heart Pathophysiology and
Preconditioning. M.J. Kearns, A. Cheung, J. Bashir,
M.A. Seidman, J.H. Boyd. UBC Ctr. for Heart & Lung
Innovation, Vancouver.
736. PERIPHERAL CIRCULATION
Poster
Exhibit Halls A-D
B137 736.1
Influence of Aerobic Fitness, Contraceptive
Use, and Height on Cardiac Augmentation Index in Young
Healthy Females. M. Smith, S. Devor. California State Univ.
Chico and The Ohio State Univ.
B138 736.2
The Adhesive Epidermal Growth Factor
Repeats of Platelet SCUBE1 Are Critical for Thrombus
Formation. M-Y. Wu, W-J. Liao, R-B. Yang. Natl. Defense Med.
Ctr. and Acad. Sinica Inst. of Biomed. Sci., Taipei.
B139 736.3
Altered Vascular Endothelial Control of Facial
Skin Blood Flow in Rosacea. K. Metzler-Wilson, M. Kube,
S. Mann, O. Demidova, D.L. Sammons, T.E. Wilson. Marian
Univ. Col. of Osteo. Med., Indianapolis and Ohio Univ.
B140 736.4
Within-Day Test-Restest Reliability of the
Single Passive Leg Movement Technique: Evidence of Clinical
Utility. R.M. Broxterman, H.J. Groot, M.J. Rossman, R.S.
Garten, M. Venturelli, O-S. Kwon, J.R. Hydren, J.R. Gifford,
R.S. Richardson. Univ. of Utah.
B141 736.5
Effect of Aging on the CO2 Reactivity and
Blowout Time in Ocular Vessels. A. Miyaji, T. Ikemura, N.
Hayashi. Tokyo Inst. of Technol. and Waseda Univ., Japan.
230
B142 736.6
Role of Metabolic and Inflammatory Biomarkers
on Femoral Artery Responsiveness in Trained Rats Fed with
Hight-Fat Diet. M.A. Delbin, A.C.S. Sponton, H.N. Araujo,
C.P. Valgas da Silva, C. de Moraes, A. Zanesco. UNICAMP,
Campinas, UNESP, Rio Claro and Univ. of São Paulo, Ribreirao
Preto, Brazil.
B143 736.7
Rescuing Age-Related Vascular Dysfunction:
The Impact of Tetrahydrobiopterin and Antioxidants. R.
Garten, J. Lee, J. Groot, M. Rossman, H. Clifton, W. Wray, R.
Richardson. Virginia Commonwealth Univ., Univ. of Utah and
Univ. of Colorado Boulder.
B144 736.8
Impact of Sodium Nitrate on Measures of
Vascular Function and Biomarkers of Inflammation in Patients
with Peripheral Artery Disease: A Preliminary Assessment. S.L.
Norton, K. Ueda, C.T. Ganger IV, D.P. Treichler, D.P. Casey.
Univ. of Iowa.
B145 736.9
Endothelin-1 Receptor Responses during
the Menstrual Cycle. K.N. Sebzda, M.M. Wenner. Univ.
of Delaware.
B146 736.10 Acute Effects of Sugar-Sweetened Beverage
Consumption on Reactive Hyperemia in Young, Healthy
Humans. J.L. Keller, E.A. Kelsch, D. Cuy Castellanos, A.R.
Crecelius. Univ. of Dayton.
B147 736.11 Endothelin-B Receptor Responses in Young
and Postmenopausal Women. A. Kuczmarski, K.N. Sebzda,
S.N. Mraz, M.M. Wenner. Univ. of Delaware.
B148 736.12 Altered Ca2+ Dynamics and Vascular Function
during Low-Flow Induced Vascular Remodeling. D.S. Weber,
C-S. Choi, L. Bayazid, K. Glosemeyer, M.S. Taylor. Univ. of
South Alabama.
737. ROS/CV INJURY I
Poster
Exhibit Halls A-D
B149 737.1
A Redox Responsive MRI Contrast Agent for
the Detection of Oxidative Stress in the Heart. D. Schwartz, M.
Yu, C.R. Goldsmith, R. Beyers, R.C. Cattley. Auburn Univ.
B150 737.2
Contribution of Prolyl Hydroxyl Binding Proteins
(PHD) to MYD88/NFkB Pathways in Nitric Oxide DeficiencyInduced Hypertensive Renal Injury. M. Choi, A. Oyekan. Texas
So. Univ.
B151 737.3
Downregulation of the Nuclear Factor
(Erythroid-Derived 2)-Like 2 (NRF2) Antioxidant Defense
System Contributes to Endothelial Dysfunction and
Microvascular Rarefaction with Elevated Dietary Salt Intake.
J.H. Lombard, K.E. Kautenburg, J.R.C. Priestley, J.M.
McCord, A.S. Greene, A.M. Geurts. Med. Col. of Wisconsin
and Univ. of Colorado Denver, Aurora.
B152 737.4
Effects of Acute TUDCA Administration
on Postprandial Hyperglycemia and Endothelial Function.
L.K. Walsh, R. Restaino, C. Manrique, J. Padilla. Univ.
B153 737.5
Effects of Acute Induced Inflammation on
Arterial Stiffness and Compliance in Overweight Adults. K.
Bunsawat, A.D. Lane-Cordova, B. Fernhall, T. Baynard.
Univ. of Illinois at Chicago and Northwestern Univ., Chicago.
B154 737.6
Tetrahydrobiopterin Prevents Congenital Heart
Defects Induced by Pregestational Diabetes. A. Engineer, Y.
Lim, T. Saiyin, X. Lu, Q. Feng. Western Univ., Canada.
SUNDAYPHYSIOLOGY
B155 737.7
Putative Sarcomeric Targets of Doxorubicin
Induced Matrix Metalloproteinase-2 Activity in Cardiomyocyctes.
A. Roczkowsky, B.Y.H. Chan, B.G. Hughes, R. Schulz. Univ.
of Alberta.
738. SEX DISPARITIES IN CARDIOVASCULAR
FUNCTION AND REMODELING
Poster
Exhibit Halls A-D
B156 738.1
Nitric Oxide Synthase and Soluble Guanylyl
Cyclase Mediate Endothelial Responses in Aged Female
Endothelial Nitric Oxide Synthase-Deficient Mice. S.P. Didion.
Univ. of Mississippi Med. Ctr.
B157 738.2
Roles of Sex-Specific Regulation of Vascular
Soluble Epoxide Hydrolase in Flow-Induced Vasodilator
Responses. J. Qin, S. Kandhi, G. Froogh, H. Jiang, D. Sun,
A. Huang. New York Med. Col.
B158 738.3
A Sex-Specific Role for Egr1 in Mediating
Norepinephrine-Induced Contraction in Mesenteric Arteries.
K.M. Thakali, E.C. Wahl, P. Kang, K. Shankar. Arkansas
Children’s Nutr. Ctr. and Univ. of Arkansas for Med. Sci.
B159 738.4
Low-Dose Aspirin during Gestation Promotes
Vascular Dysfunction and Does Not Ameliorate Maternal
Hypertension in Rats Exposed to Innate Immune System
Activation. P.A. Jaini, A. Nguyen, M. Valdes, O. Osikoya, S.
Goulopoulou. Univ. of North Texas Hlth. Sci. Ctr.
B160 738.5
Obesity-Associated Impairments in Autonomic
Control of Blood Pressure and Heart Rate Are Sex-Specific.
T. Bruder-Nascimento, O.J. Ekeledo, R. Anderson, H.B.
Le, E.J. Belin de Chantemele. Med. Col. of Georgia at
Augusta Univ.
B161 738.6
Hypertension and Type II Diabetes Are Not
Associated with Visceral Inflammation or Vascular Remodeling/
fibrosis in Obese Women. R. Fernandes, G.D. Fink, J.J.
Galligan, S.W. Watts, C. Pereira-Hicks, R.E. Watson, H. Xu,
M. Lane. Michigan State Univ.
B162 738.7
Sexual Dimorphism in Mesenteric Arterial
Function of a Novel Rat Model of Type 2 Diabetes, UC DavisType 2 Diabetes Mellitus. S. Shaligram, F. Akther, M.D.
Karimi, J.L. Graham, K.J. Stanhope, P. Havel, R. Rahimian.
Univ. of the Pacific and Univ. of California, Davis.
B163 738.8
Sex Differences in the Gene Expression Profile
of LOX-1 in Mouse Tissues. S.C. Kim, M.H. Hamblin. Tulane
Univ. Sch. of Med.
B164 738.9
Sex-Specific Transcriptomic Regulation in the
Diseased Human Heart. G. Kararigas, H. Summer, I. Baczko,
S. Golz, V. Regitz-Zagrosek. Charité Univ. Hosp., Berlin, Bayer
Hlth.Care, Wuppertal, Germany and Univ. of Szeged, Hungary.
B165 738.10 Mapping
Gender-Specific
Modifiers
of
Doxorubicin Cardiotoxicity in BN and SS Rats. M. Flister,
C. Plasterer, S. Paddock, J. Jacob, A. Lemke. Med. Col.
of Wisconsin.
B166 738.11 Gender
Differences
in
Cardiomyocyte
Adhesion Cause Heart Failure. G.L. Brower, Y. Du, E. Plante,
J.A. Stewart; Jr., J.S. Janicki. Texas Tech Univ. Hlth. Sci.
Ctr., Univ. of South Carolina, Univ. of Montreal and Mississippi
State Univ.
B167 738.12 Sex Differences in the Pulmonary Artery
Wedge Pressure Response to Exercise in Healthy Older
Adults. S. Esfandiari, S. Wright, J. Goodman, S. Mak. Univ. of
Toronto and Mount Sinai Hosp., Toronto.
B168 738.13 Decreased Systemic Microvascular Function
May Contribute to Increased Cardiovascular Risk in Women
with Asthma. K. Kapoor, L.E. Moore, B.W. Byers, M.K.
Stickland. Univ. of Alberta, Canada.
B169 738.14 Differences in Cerebral Blood Flow Regulation
in Male and Female Rugby Players with Concussions. J.
Serrador, L. Reyes, J. Tosto, M. Falvo. Rutgers Univ., Newark
and DVA East Orange, NJ.
739. RENAL HEMODYNAMICS
Poster
Exhibit Halls A-D
B170 739.1
The Chronic Effect of Tubular pH on TGF. J.
Wei, S. Wang, L. Wang, G. Zhang, J. Zhang, K-P. Yip, R. Liu.
Univ. of South Florida.
B171 739.2
ATP and Activation of P2X1 and P2X7 Renal
Receptors. A New Concept in the Pathophysiology of Renal
Vasoconstriction in Angiotensin II-Induced Hypertension. M.
Franco, R. Bautista-Pérez, A. Cano, U. Pacheco, O. PérezMendez. Natl. Inst. of Cardiol., Mexico City.
B172 739.3
A Newly Developed Technique of In
Vivo Synchrotron Radiation Renal Micro-angiography in
Spontaneously Hypertensive and Normotensive Rats. K.
Miya, S. Matsushita, K. Hyodo, C. Tokunaga, H. Sakamoto,
T. Mizutani, Y. Hiramatsu. Univ. of Tsukuba, Tsukuba
Univ. of Technol. and High Energy Accelerator Res. Org.,
Tsukuba, Japan.
B173 739.4
Development of a Novel Technique to Isolate
and Characterize Mouse Podocytes. L. H. Kung, R. Wasti, A.
Tibolla, G. Gibson, S. Pullen, S. MacDonnell. Boehringer
Ingelheim, Ridgefield, CT.
B174 739.5
Radiation-Induced
Afferent
Arteriolar
Endothelial Dysfunction Involves Decreased Epoxygenase
Metabolites. A. Sharma, M.A.H. Khan, B. Fish, E.P. Cohen,
J.D. Imig. Med. Col. of Wisconsin and Baltimore VA Med. Ctr.
B175 739.6
Internephron Coupling Increases the Efficiency
of Dynamic Autoregulation. I. Sgouralis, A. Layton. Natl. Inst.
for Math. and Biol. Syntesis, Knoxville and Duke Univ.
B176 739.7
The Role of the NADPH Oxidase Subunit
p67phox in the Regulation of Renal Blood Flow in Dahl S (SS)
Rats. L.C. Evans, A.J. Polichnowski, A.W. Cowley Jr. Med.
Col. of Wisconsin and Loyola Univ. and Hines VA Hosp.,
Maywood, IL.
B177 739.8
Individual Fluid Therapy versus Standardized
High Volume Fluid Infusion during Kidney Transplantation –
Evaluation of Oedema Development, Oxidative Stress and
Inflammation Levels, Using a Porcine Model. L.H. Nielsen.
Aarhus Univ. Hosp.-Skejby, Denmark.
B178 739.9
Effect of db-cAMP on Renal Interstitial
Hydrostatic Pressure Response to Renal Medullary Direct
Interstitial Volume Expansion (DIVE) in Rats. O. FloresSandoval, J.F. López-Rodríguez, M.E. Sánchez-Briones,
M.Z. Calvo-Turrubiartes, M. Rodríguez-Martínez. Fac. of
Med., Autonomous Univ. of San Luis Potosí, Mexico.
231
S
U
N
PHYSIOLOGYSUNDAY
B179 739.10 Components of the Innate Immune System
Induce an Increase in Mitochondrial Membrane Potential,
Reactive Oxygen Species and Necrotic Cells in Renal Medulla.
K. Robertson, S. Wildman, C. Peppiatt-Wildman. Sch. of
Pharm., Univ. of Kent, U.K.
B180 739.11 Multiparametric Determination of Renal
Hemodynamics and Oxygenation Using Non-invasive Magnetic
Resonance Imaging in Healthy Volunteers. P. Eckerbom, E.
Cox, I. Subasic, J. Weis, F. Palm, P. Hansell, S. Francis, P.
Liss. Instn. for Surg. Sci., Uppsala, Peter Mansfield MRI Ctr.,
Nottingham and Instn. for Med. Cell Biol., Uppsala.
B181 739.12 Endothelial-Derived
Hyperpolarization
In
Vivo in Hypertensive Rats. J.C. Brasen, S.U. Stannov, M.
Salomonsson, C.M. Sorensen. Tech Univ. of Denmark and
Univ. of Copenhagen.
B182 739.13 Renal Hemodynamics and Tubular Function
Are Preserved When Hydroxyethyl Starch Is Dosed to Acutely
Restore Blood Pressure after Blood Loss in Rats. Y. Fu, H.
Qiu, J. Kelada, S. Khang, S. Honndorf, V. Vallon. UCSD, VA
San Diego Healthcare Syst. and Fresenius Kabi Deutschland
GmbH, Bad Homburg.
B183 739.14 Prostamide-Mediated Protective Action of
Anandamide on Nlrp3 Inflammasome Activation in Glomeruli
of Mice with Hyperhomocysteinemia. M. Xia, G. Li, S.M.
Conley, N. Meng, K.M. Boini, J.K. Ritter, P-L. Li. Virginia
Commonwealth Univ.
B184 739.15 Impaired Renal Autoregulation after IschemiaReperfusion Results from Loss of Dynamic Stability Normally
Conferred by Tubuloglomerular Feedback. S.C. Thomson,
H. Pham, R. Bourgette, P. Singh. UCSD, VA San Diego
Healthcare Syst. and Veterans Med. Res. Fndn.
B185 739.16 Adiponectin Protects Mouse Podocytes from
Acid Ceramidase Inhibition-Induced Injury. S. Koka, M. Xia,
S.M. Conley, T.W. Gehr, N. Li, P-L. Li, K.M. Boini. Virginia
Commonwealth Univ.
B186 739.17 Visualizing Regional Kidney Blood Flow in the
Mouse. P. Cabrales, V. Jani, V.J. Hu. UCSD.
B187 739.18 Heterodyning in Tubuloglomerular Feedback
Induced Oscillations in Coupled Model Nephrons. K.J.
Kesseler, H.E. Layton. AsystBio, LLC, East Lansing and
Duke Univ.
B188 739.19 The Use of Precision-Cut Kidney Slices (Pcks)
to Investigate Intracellular Calcium Signaling and Contraction
in Small Renal Arteries of Heathy and Diabetic Nephropathy
Rats. J.F. Perez-Zoghbi, A. Roghani. Texas Tech Univ. Hlth.
Sci. Ce.
B189 739.20 NOS1β in the Macula Densa Contributes to the
Sex Differences in Decline of GFR with Aging. J. Zhang, L.
Wang, S. Wang, J. Wei, G. Zhang, K-P. Yip, R. Liu. Univ. of
South Florida.
740. DIABETIC RENAL DISEASE
Poster
Exhibit Halls A-D
B190 740.1
Elucidating the Role of Arginases in Diabetic
Nephropathy: Arginase 2-Dependent and -Independent
Effects. A.S. Awad, H. You, T. Gao, T.K. Cooper, S.M. Morris;
Jr.Penn State Col. of Med. and Univ. of Pittsburgh.
232
B191 740.2
Effect of SGLT Inhibition on Medullary Oxygen
Consumption: A Multi-nephron Model of the Rat Kidney. A.
Layton, V. Vallon, A. Edwards. Duke Univ., UCSD and Res.
Ctr. des Cordeliers, Paris.
B192 740.3
Characterization of mRNA Expression in
Mouse Renal Vasculature and Glomerulus Using Laser
Capture Microdissection. T. LoDuca, S. Kumar, C. Duris, P.E.
North, N.M. Tabatabai. Med. Col. of Wisconsin.
B193 740.4
Essential Involvement of Purinergic Signaling
in Calcium Handling in the Podocytes of Type 2 Diabetic Rats.
D. Ilatovskaya, O. Palygin, A. Lowing, V. Levchenko, J. Lazar,
A. Staruschenko. Med. Col. of Wisconsin.
B194 740.5
Dual Soluble Epoxide Hydrolase Inhibitor/
PPAR-γ Agonist Reduces Kidney Injury in Metabolic Syndrome
Rat. J. Birschbach, M.A.H. Khan, A. Sharma, M. Hartmann,
R. Blöcher, E. Proschak, J.D. Imig. Med. Col. of Wisconsin
and Goethe Univ. of Frankfurt.
B195 740.6
Mathematical Model-Based Analysis of the
Acute and Chronic Mechanisms of Diabetic Hyperfiltration. M.
Hallow, V. Vallon. Univ. of Georgia and UCSD.
B196 740.7
Oxygen Metabolic Competition in the Lactic
Acidotic Diabetic Kidney: A Point of No Return? C. Laustsen, K.
Lipsø, J.A. Østergaard, P. Mose, A. Flyvbjerg, M. Pedersen,
F. Palm, J.H. Ardenkjaer-Larsen. Aarhus Univ., Denmark,
Tech. Univ. of Denmark and Uppsala Univ., Sweden.
B197 740.8
Renal NMDA Receptors Are Increased in the
Akita Mouse Model of Type 1 Diabetes and NMDA Antagonists
Reduce Diabetic Nephropathy. S.E. Dryer, E.Y. Kim, H.
Roshanravan. Univ. of Houston.
B198 740.9
Proximal Tubular Cell Angiotensinogen
Upregulation by High Glucose Is Mediated by Reactive Oxygen
Species and Not Dependent on AT1 Receptor Activation. M.
Cypress, R. Satou, U. Hopfer, L.G. Navar. Tulane Univ. Sch.
of Med., Tulane Univ. and Case Western Reserve Sch. of Med.
B199 740.10 Renal Urea Transport Alterations with
Prolonged Renal Urea Transport Alterations with Prolonged
Hyperglycaemia. L.B. Bertelsen, P.M. Nielsen, H. Qi, T.S.
Nørlinger, X. Zhang, H.S. Jørgensen, C. Laustsen. Aarhus
Univ. and Aarhus Univ. Hosp., Denmark.
B200 740.11 ENaC Activity in the Collecting Ducts of the
STZ-Induced Type 1 Diabetic Dahl SS Rats. T.S. Pavlov, D.V.
Ilatovskaya, V. Levchenko, M.W. Brands, A. Staruschenko.
Med. Col. of Wisconsin and Med. Col. of Georgia.
B201 740.12 Increased Urinary Exosomal Kidney Injury
Molecule-1 in Patients with Type 2 Diabetes. J. George, Y-X.
Meng, M-B. Huang, J. Morgan-Billingslea, H. Garba, V.
Bond, X. Zhao. Morehouse Sch. of Med.
B202 740.13 Meprin β Deficiency Associated with Higher
Levels of Neutrophil Gelatinase Associated Lipocalin and
Kidney Injury Molecule (KIM-1) in Mice with StreptozotocinInduced Type 1 Diabetes. S.R. Kenley, J-M.V. Niyitegeka, R.
Sedighi, J. Gooding, S. Sumner, E.M. Ongeri. North Carolina
A&T State Univ. and Res. Triangle Inst. Intl., NC.
B203 740.14 Novel Differences in Renal Gene Expression
in a Diet-Induced Obesity Model of Diabetic Nephropathy. V.L.
Halperin Kuhns, J.L. Pluznick. Johns Hopkins Univ.
B204 740.15 Stimulation of Intrarenal Endothelin B
Receptors with Sarafotoxin 6c Improves Kidney Oxygenation
in Rats with Diabetic Nephropathy by Augmented Oxygen
Availability. S. Franzen, F. Palm. Linköping Univ. and
Uppsala Univ.
SUNDAYPHYSIOLOGY
B205 740.16 Meloxicam Fails to Augment the Renoprotective Effects of Soluble Epoxide Hydrolase Inhibition in
Streptozotocin-Induced Diabetic Rats via Up-Regulation of
Cytochrome P450 Hydroxylase-Mediated 20-Hete Production.
M.M. Katary, C. Pye, A.A. Elmarakby. Damanhour Univ. and
B206 740.17 ER Stress and Mitochondrial ROS Contribute
to the Development of Hypertensive-Diabetic Nephropathy. Z.
Wang, J.M. do Carmo, J.E. Hall. Univ. of Mississippi Med. Ctr.
B207 740.18 The SGLT2 Inhibitor, Empagliflozin, Attenuates
Some Markers of Renal Fibrosis without Improving Albuminuria
in Diabetic Db/Db Mice. L.A. Gallo, M.S. Ward, A.K.
Fotheringham, A. Zhuang, H. Koepsell, V. Vallon, C. Pollock,
U. Panchapakesan, J.M. Forbes. Univ. of Queensland,
Woolloongabba, Univ. of Würzburg, UCSD, VA San Diego
Healthcare Syst. and Univ. of Sydney, St. Leonards.
B208 740.19 Increased I-mfa in Mesangial Cells Contributes
to Increased Abundance of Fibronectin Protein in Diabetic
Kidney. S. Chaudhari, W. Li, Y. Wang, R. Ma. Univ. of North
Texas Hlth. Sci. Ctr.
B209 740.20 Renal Tubule-Specific Knockdown of Na+/H+
Exchanger 3 Attenuates Diabetes-Induced Increase in Kidney
Weight and Blood Pressure. A. Onishi, Y. Fu, P. Song, M.
Busslinger, M. Soleimani, V. Vallon. UCSD and VA San Diego
Healthcare Syst., Res. Inst. of Molec. Pathol., Vienna and Univ.
of Cincinnati.
B210 740.21 Knockout of Na-Glucose Transporter SGLT1
Lowers GFR and Kidney Weight in Non-diabetic and Akita
Diabetic Mice. P. Song, Y. Fu, A. Onishi, H. Qiu, H. Koepsell,
V. Vallon. UCSD and VA San Diego Healthcare Syst.,
Central South Univ., China and Inst. of Anat. and Cell Biol.,
Würzburg, Germany.
B211 740.22 Renal Effects of Glucagon-Like Peptide-1
Receptor Knockout in Akita-Diabetic Mice. P. Song, Y. Fu, H.
Qiu, A. Onishi, D.J. Drucker, V. Vallon. UCSD and VA San
Diego Hlth. Care Syst. and Mount Sinai Hosp., LunenfeldTanenbaum Res. Inst., Toronto.
B212 740.23 The Impact of Elevations of Renal Perfusion
Pressure and Hyperglycemia on MMP-2 Expression. K.C.
McPherson, J. Womack, L. Taylor, B. Fizer, D. Green, D.
Spires, J. Robinson, J.M. Williams. Univ. of Mississippi
Med. Ctr.
B213 740.24 Dysregulation of Insulin Receptor Expression
Affects Proximal Tubule Gluconeogenesis. G. Pandey, A.
Mandhani, A. Srivastava, C. Ecelbarger, K.S. Agnihotri, A.
Gaikwad, S. Tiwari. Sanjay Gandhi Post-Grad. Inst. of Med.
Sci., Lucknow, Georgetown Univ. and Central Drug Res.
Inst., Lucknow.
B214 740.25 Diet-Induced Obesity and Renal Dysfunction Is
Enhanced in Female Rats Exposed to Chronic Stress during
Early Life. M. Murphy, C. Wills, L. Gilbert, D. Cohn, A. Loria.
Univ. of Kentucky.
741. NOVEL SIGNALING AND TRANSPORT
MECHANISMS IN THE COLLECTING DUCT
Poster
Exhibit Halls A-D
B215 741.1
Lack of the Prorenin Receptor in the Collecting
Duct Blunts the ENaC Responses to Chronic Angiotensin II.
A.A. Gonzalez, V. Reverte-Ribo, A. Katsurada, C.B. Rosales,
M. Galatty, M. McLellan, O. Gentile, L.C. Veiras, D.M. Seth, A.
Ichihara, A.A. Mc Donough, M. Mamenko, O.M. Pochynyuk,
L.G. Navar, M.C. Prieto. Pontifical Catholic Univ. of Valparaíso,
Chile, Tulane Univ., Tokyo Women’s Med. Univ., Keck Sch. of
Med. of USC and Univ. of Texas Hlth. Sci. Ctr. at Houston.
B216 741.2
Regulation of 24p3 Receptor (24p3R/
SLC22A17) Expression by Tonicity in Rodent Renal
Inner Medullary Collecting Duct Cells. F. Thevenod, C.
Langelueddecke, S. Probst, B. Scharner, R. Betten, K.
Mese, B. Edemir. Univ. of Witten/Herdecke and Univ. of
Halle, Germany.
B217 741.3
ENaC in Renal Cortical Collecting Duct
Principal Cells Is Stimulated by Increasing Intracellular Ca2+ in
the Basal Compartment of the Cell via a Process Involving Src
but Not CAMK II. T.L. Thai, L. Yu, M.M. Wu, L.I. Galarza-Paez,
B.J. Duke, O. Al-Khalili, H. Ma, D.C. Eaton. Emory Univ.
B218 741.4
Gβγ
Signaling
Regulates
Aquaporin-2
Trafficking and Urinary Concentration. E.T.B. Olesen, S.B.
Poulsen, N. MacAulay, T. Rieg, R.A. Fenton. Univ. of
Copenhagen, Univ. Hosp. of Copenhagen, Aarhus Univ.,
Denmark, VA San Diego Healthcare Syst. and UCSD.
B219 741.5
(Pro)Renin Receptor Mediates Antidiuretic
Action of Vasopressin/Prostaglandin EP4 Subtype. T. Yang, X.
Lu, K. Peng, F. Wang. Univ of Utah.
B220 741.6
Lack of Adenylyl Cyclase 6 Induces Alkalosis
and Enhances Urinary Acidification. S.B. Poulsen, R.A.
Fenton, T. Rieg. Aarhus Univ., Denmark, VA San Diego
Healthcare Syst. and UCSD.
B221 741.7
EHD4 Deletion Results in a Urine Concentrating
Defect in Mice. S.S. Rahman, A.E.J. Moffitt, M. Storck, H.
Band, E.I. Boesen. Univ. of Nebraska Med. Ctr.
B222 741.8
Altered Electrolyte Homeostasis in Mice
with Collecting-Duct-Principal-Cell Select Knockout of the
Mammalian-Target-of-Rapamycin (mTOR) C.M. Ecelbarger,
M. Byrd, S. Tiwari, L. Li. Georgetown Univ. and Sanjay Gandhi
Postgrad. Inst. of Med. Sci., Lucknow.
B223 741.9
Activation of Kir4.1 Is Essential for Switching
the Function of DCT2 to DCT1 by Stimulating NCC and
Inhibiting ROMK/ENaC during Dietary K Restriction. M. Wang,
X-T. Su, P. Wu, D-H. Lin, J.A. McCormick, D.E. Ellison, W-H.
Wang. New York Med. Col. and Oregon Hlth. & Sci. Univ.
B224 741.10 High K+ Intake Attenuates ARPKD Progression
by Activation of TRPV4-Mediated Ca2+ Signaling in Cyst Cells.
M. Mamenko, V. Tomilin, O. Zaika, O. Pochynyuk. Univ. of
Texas Hlth. Sci. Ctr. at Houston.
233
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742. OXIDATIVE STRESS, MITOCHONDRIAL
METABOLISM AND REDOX CHANGES IN
HEALTH AND DISEASE
Poster
Exhibit Halls A-D
B225 742.1
Vitamin E Mitigates the Decremental Effect
of Paraquat on Substantia Nigra Neurons. M.A. Fahim,
A. Nemmar, S. Shehab, S. Dhanasekaran, J. Yasin, M.
Shafiullah, M. Hasan. Emirates Col. for Adv. Educ. and Col. of
Med. and Hlth. Sci., United Arab Emirates Univ.
B226 742.2
Increased
O-GlcNAcylation
Attenuates
Autophagic Flux, Induces Mitochondrial Dysfunction and
Leads to Accumulation of Alpha-Synuclein in Neurons. W.Y.
Wani, G. Benavides, I. Ahmad, J. Shacka, B. Chacko, J.C.
Chatham, A.J. Paterson, V.M. Darley-Usmar, J. Zhang. Univ.
of Alabama at Birmingham.
B227 742.3
Muscle Compression Causes Reduction of
Oxidative Phosphorylation (OXPHOS) Subunits and Increase
in Autophagy. B.T. Tam, B.Y. Yung, C.S. Wong, L.W. Chan,
E.W. Tam, P.M. Siu. Hong Kong Polytech Univ.
B228 742.4
Skeletal Muscle Mitochondrial Density and
Quality in Untrained and Endurance-Trained Humans. J.
Gifford, R. Garten, J. Trinity, G. Layec, R. Richardson. Univ.
of Utah and Virginia Commonwealth Univ.
B229 742.5
S-Nitrosylation of Mitochondrial Proteins
Preserves Skeletal Muscle Function from IschemiaReperfusion-Induced Injury. R.J. Wilson, M. Zhang, M.P.
Murphy, Z. Yan. Univ. of Virginia and MRC Mitochondrial Biol.
Unit, U.K.
B230 742.6
Myocardial
Matrix
Metalloproteinase-2
Activation Impairs Amplitude and Frequency of Spontaneous
Intracellular Ca2+ Transients in Doxorubicin Cardiotoxicity.
B.Y.H. Chan, B.G. Hughes, A. Roczkowsky, P. de Souza,
G. Armanious, H.S. Young, K. Ballanyi, R. Schulz. Univ. of
Alberta, Canada and Univ. Fed. do Paraná, Brazil.
B231 742.7
PKD Translocation to the Outer Mitochondrial
Membrane Induces Mitochondrial Fragmentation and Cell
Death via DLP1 Phosphorylation in Cardiomyocytes. B.S.
Jhun, J. O-Uchi, J. Mishra, X. Xu, S. Hurst, U. Mende, S-S.
Sheu. Thomas Jefferson Univ. and Rhode Island Hosp. &
Alpert Med. Sch. of Brown Univ.
B232 742.8
Decreases in Glutathione Levels Augment
VEGFR2 Activation. P.K. Prasai, C.B. Pattillo. LSU Hlth. Sci.
Ctr., Shreveport.
B233 742.9
Locomotor
and
Diaphragm
Muscle
Mitochondrial Oxidative Capacity in Lung-Targeted Vegf Gene
Deleted Mice Exposed to Cigarette Smoke. T. Witte, F. Wong,
J. Lee, J. Fine, A. Gutierrez, T. Bigby, D. Cannon, E. Breen.
UCSD, VA San Diego and San Diego State Univ.
B234 742.10 Engineered FGF21 Variant, LY2405319, Can
Protect Nonalcoholic Fatty Liver Disease through Enhancing
Hepatic Mitochondrial Function. H.K. Chung, Y.E. Kang, J.H.
Hwang, K.S. Kim, M. Shong. Chungnam Natl. Univ. Sch. of
Med., South Korea.
B235 742.11 A
Thermodynamically-Constrained
Mechanistic Mathematical Model for the Catalytic Action of
Mitochondrial Cytochrome c Oxidase. V.R. Pannala, A.KS.
Camara, R.K. Dash. Med. Col. of Wisconsin.
234
B236 742.12 The
Sex-Specific
Adaptation
of
the
Mitochondrial Lon Protease in the Model Organism, Drosophila
melanogaster L. Corrales-Diaz Pomatto, B. Shen, C. Carney,
J. Tower, K.J.A. Davies. Univ. of So. California.
B237 742.13 A Case of Mistaken Identity: Are Reactive
Oxygen Species Actually Reactive Sulfide Species? K.R.
Olson, Y. Gao, E. Huang, M. Arif, N. Arora, A. Divietro, S.
Patel, E.R. Deleon. Indiana Univ. Sch. Med. South Bend and
Univ. of Notre Dame.
B238 742.14 Quantitative Ex Vivo Imaging of Tissue O2
Reveals Effects of Inflammation, Mitochondrial Respiration
and ROS Production on O2 Levels in Colonic Mucosa. A.V.
Zhdanov, I.A. Okkelman, A.V. Golubeva, G. Aviello, S. Melgar,
N.P. Hyland, U.G. Knaus, J.F. Cryan, D.B. Papkovsky. Sch. of
Biochem. and Cell Biol., University Col. Cork and Sch. of Med.,
University Col. Dublin.
B239 742.15 Histone Deacetylase Inhibitors Suppress
Transcription of NADPH Oxidases and Ameliorate Pulmonary
Hypertension. S.B. Haigh, F. Chen, X. Li, M.L. Meadows, J.
Zhou, D. Stepp, N. Weintraub, S. Barman, D. Fulton. Med.
Col. of Georgia at Augusta Univ.
B240 742.16 Antitumor Activity of Salvianolic Acid against
Ehrilich Solid Carcinoma in Swiss Albino Mice. M. Katary, A.
Elmarakby. Damnhour Univ., Egypt and GRU Univ., Augusta.
B241 742.17 Glutathione (GSH) Absolute Synthesis Rates
(ASR) of Multiple Organs in a Pseudomonas aeroginosa (PM)
Induced Hyperdynamic Sepsis Pig Model. G.A. Ten Have, M.P.
Engelen, R.R. Wolfe, N.E. Deutz. Texas A&M Univ. and Univ.
of Arkansas for Med. Sci.
743. MICRORNAS IN HEALTH AND DISEASE
Poster
Exhibit Halls A-D
B242 743.1
Denervation Alters microRNA Expression
Profiles of Microvesicles Released by Cultured Muscle Fibers.
S. Hamidi, R. De Gasperi, L.M. Harlow, H. Ksiezak-Reding,
W.A. Bauman, C.P. Cardozo. James J. Peter VA Med. Ctr.,
Bronx and Icahn Sch. of Med. at Mount Sinai.
B243 743.2
Regulation of Dicer-Mediated MicroRNA
Maturation by β-Arrestin-Biased Agonism of β-Adrenergic
Receptor: A New Cardioprotective Mechanism. I-m. Kim, J-p.
Teoh, A. Bayoumi, Z. Broskova. Med. Col. of Georgia at
Augusta Univ.
B244 743.3
Investigation of MicroRNA Expression Profiles
in the Susceptible Population to In-Stent Restenosis. C-J. Chen,
C-H. Wu, S. Chun-Ming, C-Y. Huang, W-F. Bi, C-S. Chan, Y-T.
Kao, C-H. Pan, S-J. Chiang, K-H. Chiang, Y-R. Liu, J-D. Luo.
Taipei Med. Univ. and Taipei Med. Univ. Hosp., Taiwan.
B245 743.4
Circulating MicroRNA and Isomir Profiles
in Patients with Varying CVD Severity: Using isomiRs as
Potential Biomarkers and Therapeutic Targets. A.M. James, S.
Thomas, K. Rooney, C.D. Searles. Emory Univ. Sch. of Med.
and Atlanta VA Med. Ctr.
B246 743.5
Chronic Alcohol Ingestion Induces Alveolar
Macrophage Oxidative Stress and Phagocytic Dysfunction by
Down-Regulating NADPH Oxidase-Related microRNAs. S.M.
Yeligar, F.L. Harris, C.M. Hart, L.A.S. Brown. Emory Univ.,
Dacatur and Atlanta.
SUNDAYPHYSIOLOGY
744. MICROBIOTA OR NUTRITION AND HOST
CELL SIGNALING
Poster
Exhibit Halls A-D
B247 744.1
Interplay between Nutrition and Environment
in Altering the Gut Microbiome and Susceptibility to Type 2
Diabetes. M. Schaid, J. Neuman, J. Wisinski, A. Reuter, E.
Laundre, R. Fenske, M. Kimple. Univ. of Wisconsin-Madison.
B248 744.2
Comparative Analysis of Biotransformation of
trans-Resveratrol in Worms, Flies, Mice and Humans. S.E.
Kulling, S.T. Soukup, F. Rieck, B. Spanier, C. Schulze,
S. Piegholdt, G. Rechkemmer, A.E. Wagner, A. Bub, G.
Rimbach, H. Daniel. Max Rubner Inst., Karlsruhe, TU München
and Univ. of Kiel, Germany.
B249 744.3
Coxiella burnetii Infection of Host Cells
Involves PKC Substrate MARCKS. S. Whitlock, C.J. Funk.
John Brown Univ.
B250 744.4
Renal Olfactory Receptor 90 Responds to
Fungal Metabolites. V.L. Halperin Kuhns, J.L. Pluznick.
Johns Hopkins Univ.
B251 744.5
Mechanism of Action of Lactobacillus reuteri
ATCC PTA 6475 in Colon Epithelial Cells. N.D. Rios-Arce, R.A.
Britton, L. McCabe, N. Parameswaran. Michigan State Univ.
and Baylor Col. of Med.
B252 744.6
EriC2 Regulates Histamine Production
Machinery via an Ion Transport-Dependent Mechanism in
Lactobacillus reuteri A. Hall, M. Engevik, J. Versalovic. Baylor
Col. of Med. and Texas Children’s Hosp.
745. CELLULAR RESPONSES TO INFLAMMATION
Poster
Exhibit Halls A-D
B253 745.1
Purinergic Signaling in Sepsis Induced by
α-Hemolysin Producing Escherichia coli in Mice. A-S. Greve,
H.A. Praetorius, M. Skals. Aarhus Univ., Denmark.
B254 745.2
Exocytosis of Endothelial Lysosome-Related
Organelles Hair-Triggers a Patchy Loss of Glycocalyx at the
Onset of Sepsis. J.A. Zullo, J. Fan, T. Azar, W. Yen, M. Zeng,
J. Chen, B. Ratliff, J. Song, J.M. Tarbell, M.S. Goligorsky, B.
Fu. New York Med. Col., City Col. of CUNY and Ulsan Med.
Col., South Korea.
B255 745.3
Pulsed Ultrasound Stimulation Prevents
Bacterial Lipopolysaccharide-Induced Muscle Wasting
and p38 MAPK Phosphorylation in Mouse C2C12 Skeletal
Myotubes. M. Ueno, N. Maeshige, Y. Hirayama, R. Nakanishi,
M. Yoshikawa, H. Fujino. Kobe Univ., Japan.
B256 745.4
The Role of P2X7R in Priming the NLRP3
Inflammasome after Mechanical Strain. F. Albalawi, W. Lu, J.
Lim, C.H. Mitchell. Univ. of Pennsylvania.
B257 745.5
Training Enhances the Recovery of Monocyte
Subset Response to a Bout of Resistance Exercise. A.R.
Jajtner, J.R. Hoffman, J.R. Townsend, K.S. Beyer, A.N.
Varanoske, D.D. Church, J.J. Riffe, T.W.D. Muddle, S.
Radom-Aizik, D.H. Fukuda, J.R. Stoute. Univ. of Central
Florida and Univ. of California-Irvine.
B258 745.6
Essential Role of Pituitary Tumor Transforming
Gene-1In Vascular Endothelial Cell Activation and Remodeling.
L. Yin, B. Yi, X. Wei, G. Zhang, Y. Yin, Z. Guo, F. Cheng, J.
Sun. Thomas Jefferson Univ. and Shanxi Med. Univ., China.
B259 745.7
Age-Related
Changes
in
Macrophage
Proliferative Capacity in Response to Chronic Inflammation
and Inhaled Ozone. Z. Liu, A. Groves, T. Golden, D. Laskin,
A. Gow. Rutgers Univ., Piscataway.
746. CELLULAR RESPONSE TO HYPOXIA
Poster
Exhibit Halls A-D
B260 746.1
Intermittent and Sustained Hypoxia Exacerbate
the Neonatal Microglial Inflammatory Response to TLR4
Ligands. E.A. Kiernan, A. Gardner, E.A. Langenstroer, J.J.
Watters. Univ. of Wisconsin-Madison.
B261 746.2
Microglial
Inflammatory
Responses
to
Systemic Immune Challenge Are Attenuated over the Course
of Chronic Intermittent Hypoxia Exposure. J.N. Ouellette,
S.M.C. Smith, J.J. Watters. Univ. of Wisconsin-Madison.
B262 746.3
Mitigation of Hypoxic-Ischemic Damage in
Newborn Rats by Misoprostol, a Prostaglandin E2 Receptor
Agonist. M. Martens, C. Blaney, A. Archiblad, L. Nguyen, C.
Rampitsch, J. Gordon, T. Ivanco, W.L. Diehl-Jones. Univ.
of Manitoba, Childrens Hosp. Res. Inst. of Manitoba, Agr.
Canada, Winnipeg and Athabasca Univ., Canada.
B263 746.4
Counter-Regulation of the HIF-Dependent
Adaptive Response to Hypoxia by Hypercapnia. C. Taylor, A.
Selfridge, M. Cavadas, C. Scholz, E. Cambpell, L. Welch,
E. Lecuonah, S. Colgan, K. Barrett, P. Sporn, J. Sznajder,
E. Cummins. University Col. Dublin, Univ. of Zurich, Univ. of
Colorado Denver, Northwestern Univ.,Chicago and UCSD.
B264 746.5
Effects of Hypoxia on Intracellular H2S and
Polysulfides: Implications in O2 Sensing. E.R. Deleon, E.
Huang, Y. Gao, K.R. Olson. Indiana Univ. Sch. Med. South
Bend and Univ. of Notre Dame.
B265 746.6
Contribution of Endogenous Hydrogen Sulfide
to Hypoxic Inhibition of Sodium Transport by Lung Epithelial
Cells. M. Althaus, N.C. Krause, J. Pott, L.K. Münch, K.R.
Olson. Justus Liebig Univ., Germany and Indiana Univ. Sch. of
Med.-South Bend.
B266 746.7
Effect of Hypoxia on Fibroblast Proliferation in
Idiopathic Pulmonary Fibrosis. L.K. Senavirathna, C. Huang,
L. Liu. Oklahoma State Univ.
B267 746.8
Investigating the Role of Mitochondrial Fission
in Cardiac Myocyte Hypoxia/Re-oxygenation-Induced Cell
Death. A.M. Pratt, E. Heine, Q. Chen, R. Barsotti, L. Young.
Philadelphia Col. of Osteo. Med.
235
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747. APOPTOSIS, CELL STRESS AND CELL DEATH
Poster
Exhibit Halls A-D
B268 747.1
DLP1-Dependent Mitochondrial Fragmentation
Mediates Heat Shock-Induced Injury in Mouse C2C12 Skeletal
Muscle Cells. T. Yu, P. Deuster, Y. Chen. Uniformed Svcs. Univ.
of Hlth. Sci.
B269 747.2
A Novel Interaction between Thyroid Receptor
Interacting Protein 13 with Tetratricopeptide Repeat Domain
5 Regulates p53 Activity in Murine Inner Medullary Collecting
Duct Cells. T. Hama, J.D. Pressly, S. O’Brien, F. Park. Univ. of
Tennessee Hlth. Sci. Ctr., Col. of Pharm.
B270 747.3
CT20p-Induced Autophagy in Breast Cancer
Cells Can Be Overcome by Co-treatment with 3-Methyladenine
to Maximize Cell Death. M.W. Lee, C. Moskowitz, J.M. Perez,
A. Khaled. Univ. of Texas at Austin Dell Med. Sch., Univ. of
Central Florida Col. of Med. and Cedars-Sinai.
B271 747.4
Emergence of Apoptotic Features after Glcine
Cytoprotection against ATP Depletion-Induced Necrotic Killing
of Rat Hepatocytes. L. Li, J.J. Lemasters. Med. Univ. of South
Carolina and Inst. of Theoret. and Exptl. Biophys., Moscow
region, Russia.
B272 747.5
P2X Receptor Inhibition Protects THP1 Monocytes against Cytolysis by α-Hemolysin from
Escherichia coli and Leukotoxin from Aggregatibacter
actinomycetemcomitans S.K. Fagerberg, M.G. Skals, H.A.
Praetorius. Aarhus Univ., Denmark.
B273 747.6
Vanadium Complexes Inhibit Growth of HT29 Cells via ROS Generation. B. Moretti, V. McCaffrey, B.J.
Rabquer. Albion Col., MI.
B274 747.7
BNIP3 Regulation of Intracellular Calcium. J.
Field, S. da Silva Rosa, W. Mughal, Y. Hai, J. Gordon, W.L.
Diehl-Jones. Col. of Nursing, Univ. of Manitoba and Athabasca
Univ., Canada.
748. STEM CELLS, CELL GROWTH, DEVELOPMENT,
DIFFERENTIATION, AND AUTOPHAGY
Poster
Exhibit Halls A-D
B275 748.1
Examination
of
the
Development
of
Gastrointestinal Brunner’s Glands: Stem Cells and
Differentiation Factors. A. Powell, M. Parappilly, Y-H. Lo, T.
Lantz, N. Shroyer. Univ. of Oregon and Baylor Col. of Med.
B276 748.2
Umbilical Cord Stromal Cell Exosomes Protect
Tubular Epithelial Cells from Gentamicin Injury. F.T. Borges, A.
Novaes, N. Schor. Univ. Cruzeiro do Sul and UNIFESP, São Paulo.
B277 748.3
Pharmacological Activation of LPA Receptors
Regulates Erythro-megakaryocytic Differentiation in Myeloid
Lineage. J-C. Chiang, K-H. Lin, Y-S. Ho, C-L. Yao, H. Lee.
Natl. Taiwan Univ. and Yuan-Ze Univ., Taiwan.
236
B278 748.4
Generation of Induced Pluripotent Stem
Cells from Epstein-Barr Virus Immortalized Lymphoblastoid
Cell Lines Using Episomal Vectors. K. Saito, C. Mayhew, L.
Stanton, J.A. Towbin, E. Purevjav. Univ. of Tennessee Hlth.
Sci. Ctr. and Cincinnati Children’s Hosp. Med. Ctr.
B279 748.5
5-Methoxytryptophan Prevents High-Glucose
Induced Mesenchymal Stem Cell Senescence through
Alteration of Lysosome Mass. T-C. Chang, Y-C. Shiue, M-F.
Hsu, K.K. Wu. China Med. Univ. Hosp. and China Med.
Univ.,Taichung and NHRI, Miaoli, Taiwan.
B280 748.6
Disruption of the Mouse Tip110 Gene Leads
to Early Post-implantation Lethality and Prohibits Embryonic
Stem Cell Development. A.J. Whitmill, J. He. Univ. of North
Texas Hlth. Sci. Ctr. at Fort Worth.
B281 748.7
Examining the Functional Role of Fragile
X Related Protein 1 in Adult Neurogenesis. N. Patzlaff, K.
Nemec, X. Zhao. Univ. of Wisconsin-Madison, Sch. of Med.
and Publ. Hlth.
749. BRAIN DEVELOPMENT AND AGING
Poster
Exhibit Halls A-D
B282 749.1
Sexually Dimorphic Expression of RNA
Processing Genes in the Developing Mouse Cortex and
Hippocampus. M.K. Franklin, C. Armoskus, C. Donovan,
H-W. Tsai. California State Univ., Long Beach.
B283 749.2
Effect of Age on Sexually Dimorphic Expression
of X-Linked Genes in the Developing Mouse Cortex and
Hippocampus. D. Moreira, C. Armoskus, F. Rath, R. Reyes,
H-W. Tsai. California State Univ. Long Beach.
B284 749.3
Regulation of the Sexually Dimorphic Gene,
Rora, in the Developing Mouse Cerebellum Is Independent
of Sex Steroids. T. Mota, H-W. Tsai. California State Univ.,
Long Beach.
B285 749.4
Loss of Cdk5 Function May Mediate AgeRelated Decline in Voluntary Physical Activity. G. Ruegsegger,
R. Toedebusch, F. Booth. Univ. of Missouri-Columbia.
B286 749.5
Multisensory Integration in the Developing
Brain of the Xenopus laevis Tadpole. O.A. Carrillo, T.
Truszkowski. Brown Univ.
B287 749.6
fMRI-Based Method to Describe Human Brain
Size as a Function of Age and Height. M. Obatusin, L.A.
Reyes, J.M. Serrador, G.D. Wylie. VA New Jersey Healthcare
Syst., East Orange, Rutgers Biomed. and Hlth. Sci., Newark
and Kessler Fndn., West Orange, NJ.
B288 749.7
Exposure to a Diet High in Saturated-Fat
during Pre-natal and Post-weaning Brain Development Alters
Hippocampal Gene Expression and Behavioral Indices for
Anxiety and Depression. K.C. Page, M.E. Winkelmann, E.K.
Anday. Bucknell Univ. and Drexel Univ. Col. of Med.
B289 749.8
Aging and the Microbiota-Gut-Brain Axis:
Increased Gut Permeability, Altered Gut Microbiota Composition
and Increased Peripheral Inflammation Are Associated with
Neurobehavioural Effects in Aged Mice. K.A. Scott, M. Ida,
J.A. Prenderville, G.M. Moloney, T. Izumo, A. Murphy, R.P.
Ross, C. Stanton, T.G. Dinan, J.F. Cryan. University Col.
Cork, Suntory World Res. Ctr., Kyoto and Teagasc, Ireland.
SUNDAYPHYSIOLOGY
750. CENTRAL REGULATION OF FOOD INTAKE AND
BODY WEIGHT
Poster
Exhibit Halls A-D
B290 750.1
Long-Term Body Weight Regulation by the
Central Melanocortin System Appears to Be Dissociated from
Food Intake. I. Cote, Y. Sakarya, N. Kirichenko, D. Morgan, C.
Carter, N. Tumer, P. Scarpace. Univ. of Florida.
B291 750.2
Role of Brainstem Melanocortin-4 Receptor in
Regulating Glucose, Energy Balance and Body Fat in Female
Mice. T. Fang, J.M. do Carmo, Z. Wang, N. Aberdein, C. Perez
de Lara Rodriguez, J.E. Hall. Univ. of Mississippi Med. Ctr.
B292 750.3
Bardet-Biedl Syndrome Proteins in AgRP
Neurons Are Required for Energy Homeostasis. D.F. Guo, K.
Rahmouni. Univ. of Iowa.
B293 750.4
Bardet-Biedl Syndrome 1 Gene in The
Ventromedial Hypothalamus Is Required for Energy Homeostasis.
M. Rouabhi, D.F. Guo, K. Rahmouni. Univ. of Iowa.
751. CENTRAL REGULATION OF BODY
FLUID HOMEOSTASIS
Poster
Exhibit Halls A-D
B294 751.1
Optogenetic Stimulation of Distinct Populations
of Anterior Preoptic Neurons Reveals a Locus for the Reciprocal
Control of Thirst. S.B. Abbott, J.C. Geerling, C.B. Saper.
Heart Res. Inst., Sydney and Beth Israel Deaconess Med. Ctr.
B295 751.2
Brain Epithelial Sodium Channel Contributes
to Thirst Stimulated by Hypernatremia. H.L. Nation, S.S.
Simmonds, S.D. Stocker. Penn State Col. of Med.
B296 751.3
DREADD (Designer Receptors Exclusively
Activated by Designer Drugs)-Induced Activation of Subfornical
Organ Neurons Stimulates Thirst and Salt Appetite. M.H.
Nicoleau, H. Nation, B. Kinsman, K. Browning, S.D. Stocker.
Franklin and Marshall Col., PA and Penn State Col. of Med.
B297 751.4
Increases in Cerebrospinal Fluid NaCl
Concentration Excites Neurons of the Organum Vasculosum of
the Lamina Terminalis to Elevate Sympathetic Outflow and Blood
Pressure. S.S. Simmonds, S.D. Stocker. Penn State Col. of Med.
752. SYMPATHETIC CONTROL OF
THE CIRCULATION
Poster
Exhibit Halls A-D
B298 752.1
Prior Exercise and Changes in Plasma Volume
Cause Differential Baroreflex Responses to Head-Up Tilt. N.
Charkoudian, R.W. Kenefick, E.M. Caruso, A.J. Luippold,
K.R. Heavens, S.N. Cheuvront. U.S. Army Res. Inst. of Exptl.
Med., Natick, MA.
B299 752.2
Brief
Isocapnic
Hyperoxia
Increases
Sympathetic Vascular Transduction during Sympathoexcitatory
Maneuvers in Healthy Humans. B.M. Silva, A.C. Machado,
L.C. Vianna, T.C. Barbosa, E. Prodel, I.A. Fernandes, A.C.
Nobrega. Fed. Univ. of São Paulo, Fluminense Fed. Univ. and
Univ. of Brasília, Brazil.
B300 752.3
Can Augmented Sympathetic Activity in
Rosacea Be Tracked by Cutaneous Flowmotion? T.E. Wilson,
E. Eaton, K. Toma, A. Jurovcik, D. Sammons, K. MetzlerWilson. Marian Univ. Col. of Osteo. Med., Marshall Univ. and
Ohio Univ. Heritage Col. of Osteo. Med.
B301 752.4
ATP Maintains the Ability to Blunt α1-Adrenergic
Vasoconstriction during Combined Blockade of Nitric Oxide,
Prostaglandins, Na+/K+-ATPase, and KIR channels. C.M.
Hearon; Jr., J.C. Richards, G.J. Luckasen, D.G. Larson, M.J.
Joyner, F.A. Dinenno. Colorado State Univ., Poudre Valley
Hlth. Syst., Med. Ctr. of Rockies Fndn., Mayo Clin. and Ctr. for
Cardiovasc. Res., Fort Collins.
B302 752.5
Vasodilation and Hyperemia during Passive
Limb Movement: Impact of Acute Sympathetic Activation. J.D.
Trinity, J.F. Lee, R.S. Garten, Z. Barrett O’Keefe, G. Layec,
D.W. Wray, R.S. Richardson. Salt Lake City VA Med. Ctr. and
Univ. of Utah.
B303 752.6
Time Course of Structural and Functional
Adaptations of Mesenteric Resistance Vasculature after High
Thoracic Spinal Cord Injury. D. Popok, C. West, B. Frias,
I. Laher, A. Krassioukov. Univ. of British Columbia and
Vancouver Coastal Hlth., Canada.
B304 752.7
Ca2+ Transients in and Release of
Norepinephrine from Sympathetic Varicosities in Rat Mesenteric
Small Arteries – Importance for Force Development. C.
Aalkjaer, O. Tarasova, H. Nilsson. Univ. of Aarhus, Denmark,
Moscow State Univ. and Univ. of Gothenburg, Sweden.
B305 752.8
Acute Slow-Paced Breathing Modulates the
Pressor and Depressor Responses following Spontaneous
Oscillations in Muscle Sympathetic Nerve Activity. L.C. Vianna,
P.J. Fadel, M.J. Joyner, E.A. Wehrwein. Univ. of Brasilia, Univ.
of Taxas at Arlington, Mayo Clin. and Michigan State Univ.
753. ARTERIAL BAROREFLEX FUNCTION AND
BLOOD PRESSURE REGULATION
Poster
Exhibit Halls A-D
B306 753.1
Dynamic Carotid Baroreflex Function at the
Onset of Leg Cycling. T. Barbosa, L. Vianna, T. Hashimoto, L.
Petersen, N. Olesen, H. Tsukamoto, H. Sørensen, S. Ogoh,
A. Nobrega, N. Secher. Fluminense Fed. Univ., Brazil, Univ. of
Copenhagen, Univ. of Brasilia, Ritsumeikan Univ., Japan and
Toyo Univ., Japan.
B307 753.2
ARMAX-Based Method Extends Knowledge of
the Baroreflex. M.T. Lund, M. Salomonsson, T.E.N. Jonassen,
N-H. von Holstein-Rathlou. Univ. of Copenhagen.
B308 753.3
Impaired Arterial Pressure Stability Is
Improved by Sodium-Glucose Co-transporter 2 Inhibitor in
Streptozotocin-Induced Diabetic Rat. T. Yoshikawa, T. Kishi,
Y. Hirooka. Kyushu Univ. Grad. Sch. of Med. Sci. and Cr. for
Disruptive Cardiovasc. Med., Japan.
237
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PHYSIOLOGYSUNDAY
B309 753.4
Fish Oil Supplementation Attenuates Blood
Pressure Response but Not Renal Vasoconstrictor Response
to Orthostatic Stress in Healthy Older Humans. R.C. Drew,
C.M. Clark, K.D. Monahan. Penn State Col. of Med.
B310 753.5
Intermittent Hypoxia Decreases Baroreflex
Sensitivity in Healthy Humans. Z.M. Scruggs, L.P. Newhouse,
M.J. Joyner, T.B. Curry, J.K. Limberg. Mayo Clin.
B311 753.6
pSer40
Tyrosine
Hydroxylase
Immunohistochemistry Identifies the Anatomical Location of
C1 Neurons in Rat RVLM That Are Activated by Hypotension.
P.M. Pilowsky, P.E. Nedoboy, S. Mohammed, K. Kapoor,
A.M. Bhandare, M.M.J. Farnham. Univ. of Sydney and Heart
Res. Inst., Newtown.
B312 753.7
Functional Changes of Baroreceptor Afferent,
Central and Vagal Efferent Components in the Baroreflex Arc:
Effects of SOD1 Overexpression in Mice. J. Chen, J. Hatcher,
H. Gu, Z.J. Cheng. Burnett Sch. of Biomed. Sci., Univ. of
Central Florida.
B313 753.8
Baroreflex Function and Salt Sensitivity among
Normotensives. E.L. Matthews, D.E. Coyle, M.S. Brian, D.G.
Edwards, S.D. Stocker, W.B. Farquhar. Univ. of Delaware and
B314 753.9
Exercise Training Improves the Arterial
Baroreflex Function in Hypertensive Rats. Y-X. Pan, L. Hong,
X-L. Zhao, C. Lin. Fujian Med. Univ., China.
754. AUTONOMIC BALANCE: SYMPATHETIC
AND PARASYMPATHETIC
Poster
Exhibit Halls A-D
B315 754.1
Effect of Electroacupuncture on Cardiac
Excitability during Sympathoexcitation Induced by Acute
Ischemia and Left Stellate Ganglion Stimulation in a
Porcine Model. W. Zhou, T. Takamiya, K. Yamamoto, A.
Mahajan. UCLA.
B316 754.2
The Correlation between Heart Rate Variability
and Diet. O. Murray, R. Vick. Elon Univ.
B317 754.3
Transcutaneous Vagus Nerve Stimulation
Decreases Sympathetic Nerve Activity in Older Healthy
Human Subjects. A.R. Murray, J.A. Clancy, S.A. Deuchars, J.
Deuchars. Univ. of Leeds, U.K.
B318 754.4
The Effect of Oral Hygiene on Cardiac Health
as Determined by Heart Rate Variability. E.E. Bujnoski. Elon
Univ.
B319 754.5
Analysis of Heart Rate Variability by Multiscale
Entropy in Spontaneously Hypertensive Rats. L.E.V. Silva,
C.A.A. Silva, H.C. Salgado, R. Fazan; Jr. Sch. of Med. of
Ribeirão Preto, Brazil.
B320 754.6
Electrical Stimulation of the Carotid Sinus
Nerve Improves Hemodynamics and Heart Rate Variability in
L-NAME Hypertensive Rats. G.D. Souza, L.E.V. Silva, D.P.
Martins Dias, F.M. Santos-Almeida, J.A. Castania, H.C.
Salgado, R. Fazan; Jr. Sch. of Med. of Ribeirão Preto, Brazil.
B321 754.7
Angiotensin-(1-7) Delays Onset of Dilated
Cardiomyopathy in Mice with Muscular Dystrophy. R.
Sabharwal, L. Yang. Univ. of Iowa.
238
755. CHEMOREFLEX FUNCTION AND
AUTONOMIC REGULATION
Poster
Exhibit Halls A-D
B322 755.1
Cardiorespiratory Control in Newborn Rats
Submitted to Chronic Intermittent Hypoxia. M.F. Menezes, D.
Zoccal. São Paulo State Univ., Araraquara.
B323 755.2
The Comparison of Multiple Chemosensitivity
Tests in Healthy Adults. S.É. Collins, D.P. Fuhr, W.W.
Michaelchuk, B.W. Byers, M.K. Stickland. Univ. of Alberta and
Covenant Hlth., Edmonton, AB, Canada.
B324 755.3
Enhanced Carotid Body-Mediated Chemoreflex
Drive in Heart Failure: A Matter of Flow. D.C. Andrade, H.D.
Schultz, N.J. Marcus, C. Toledo, C. Lucero, R. Del Rio. Univ.
Autón. de Chile, Univ. of Nebraska Med. Ctr. and Des Moines Univ.
B325 755.4
The Effect of Pulmonary Rehabilitation on
Carotid Chemoreceptor Activity and Sensitivity in COPD. B.W.
Byers, D.P. Fuhr, L.E. Moore, M. Bhutani, E. Wong, M.K.
Stickland. Univ. of Alberta.
B326 755.5
Carotid Body Removal Markedly Improves
Survival via Sympathoinhibition, Depressor Response and
Leftward Shifting of the Pressure-Natriuresis Curve in Dahl
Salt -Sensitive Rats. K. Fujii, K. Saku, Y. Oga, A. Nishizaki,
T. Akashi, T. Takehara, T. Kishi, K. Sunagawa. Kyushu Univ.
Grad. Sch. of Med. Sci. and Kyushu Univ. Hosp., Japan.
B327 755.6
Sleep Apnea Worsens Muscle Vasoconstriction
during Central and Peripheral Chemoreceptors Stimulation in
Patients with Systolic Heart Failure. D.M.L. Lobo, P.F. Trevizan,
E. Toschi-Dias, P.A. Oliveira, R.B. Piveta, C. Mady, E.A.
Bocchi, D.R. Almeida, G. Lorenzi-Filho, H.R. Middlekauff,
C.E. Negrão. Heart Inst., Univ. of São Paulo Med. Sch., Fed.
Univ. of São Paulo and Geffen Sch. of Med. at UCLA.
B328 755.7
Localization of Corticotropin Releasing Factor
Receptor 2 in the Nucleus Tractus Solitarii. B.C. Ruyle, G.F.
Callanan, M.M. Haney, K.M. Coldren, C.M. Heesch, E.M.
Hasser. Univ. of Missouri-Columbia.
B329 755.8
Leptin Facilitates Phrenic and Abdominal Nerve
Activity during Chemoreflex Activation. M. Bassi, W.I. Furuya,
D.B. Zoccal, J.V. Menani, D.S. Colombari, E. Colombari. Sch.
of Dent. and São Paulo State Univ.
B330 755.9
Chemoreflex Activation of Neuroendocrine versus
Pre-sympathetic Corticotropin Releasing Hormone Neurons in the
Paraventricular Nucleus of the Hypothalamus: Continuous Acute
Hypoxia and Intermittent Sodium Cyanide. K.M. Coldren, D.D.
Kline, E.M. Hasser, C.M. Heesch. Univ. of Missouri-Columbia.
756. SYMPATHETIC AND PARASYMPATHETIC
REGULATION IN DISEASE
Poster
Exhibit Halls A-D
B420 756.1
Renal Afferent Peptidergic Neurons – What
Are Primary Stimuli? T. Ditting, K. Rodinova, S. Loosen, K.
Hilgers, C. Ott, R.E. Schmieder, K. Amann, R. Veelken. Univ.
of Erlangen-Nuremberg, Germany.
SUNDAYPHYSIOLOGY
B421 756.2
Pro-arrhythmic Effects of the Cardiac
Sympathetic Co-transmitter, Neuropeptide-Y, during IschemiaReperfusion and ST Elevation Myocardial Infarction. N.
Herring, M. Kalla, E. Dall’Armellina, L. Woodward, C-J. Lu,
A. Banning, B. Prendergast, J.C. Forfar, R. Choudhury, K.
Channon, R. Kharbanda, D. Paterson. Univ. of Oxford.
B422 756.3
Developing Manganese-Enhanced MRI as a
Non-invasive Measure of In Vivo Neuronal Activity in the Rostral
Ventrolateral Medulla of Sedentary and Physically Active Rats.
D.J. Huereca, A.G. Holt, B.A. Berkowitz, P.J. Mueller. Wayne
State Univ. Sch. of Med.
B423 756.4
Rostrocaudal Changes in the Protein
Expression of GABAA Receptor Subunits in the Rostral
Ventrolateral Medulla of Sedentary and Physically Active Rats.
P.J. Mueller, M.D. Dombrowski, B.E. Fyk-Kolodziej. Wayne
State Univ. Sch. of Med.
B424 756.5
Effect of Six Months of Cardiac Rehabilitation
on Autonomic Function in Coronary Artery Disease Patients.
M.B. Badrov, K.N. Norton, S. Lalande, N. Suskin, J.K.
Shoemaker. Sch. of Kinesiol., Western Univ. and St. Joseph’s
Hosp. London, Canada.
B425 756.6
Cardiovascular Autonomic Tone in Rats with
Heart Failure Treated with Allogeneic Mesenchymal Stem Cells.
S.D.B.V. Morais, R.M. Lataro, C.A.A. Silva, L.S. Meirelles, R.
Fazan. Jr., H.C. Salgado. Sch. of Med. of Ribeirão Preto and
Lutheran Univ. of Brazil.
757. NCAR YOUNG INVESTIGATOR AWARDS
Poster
Exhibit Halls A-D
B426 757.1
Norepinephrine-Mediated Suppression of
T-Lymphocyte Activation Is Regulated by Mitochondrial Redox
Mechanisms. A.J. Case, M.C. Zimmerman. Univ. of Nebraska
Med. Ctr.
B427 757.2
Central Anti-inflammatory and Neuronal Effects
of Butyrate in Wistar Kyoto and Spontaneously Hypertensive
Rats. T. Yang, V. Rodriguez, L. Colon-Perez, T. Redler, M.
Febo, C. Sumners, J. Zubcevic. Univ. of Florida.
B428 757.3
Renal
Nerves,
Renal
Inflammation
and Hypertension in Deoxycorticosterone Acetate-Salt
Hypertension: Who Is in the Driver’s Seat? C.T. Banek, J.D.
Foss, D.A. Van Helden, N. Asirvatham-Jeyaraj, J.W. Osborn.
Univ. of Minnesota, Minneapolis and Vanderbilt Univ.
B429 757.4
Renal Function in Normotensive Sheep in the
First Fourteen Weeks after Catheter-Based Renal Denervation.
L.C. Booth, Z. McArdle, S.T. Yao, S. Malone, Y. Lankadeva, J.
Kosaka, M. Schlaich, C.N. May. Florey Inst. of Neurosci. and
Ment. Hlth. and IDI Heart & Diabetes Inst., Melbourne.
B430 757.5
Neuronal Activation of ADAM17 by AT1A
Receptors Contributes to Neurogenic Hypertension. J. Xu, S.
Sriramula, E. Lazartigues. LSU Hlth. Sci. Ctr., New Orleans.
B431 757.6
Prostaglandin E2 and Its EP3 Receptors
Contribute to Dendritic Cell and Memory T Cell Activation
in Mice with L-NAME/High Salt-Induced Hypertension. L.
Xiao, H.A. Itani, M.P. Kraemer, R.M. Breyer, D.G. Harrison.
Vanderbilt Univ.
B432 757.7
Active Expiration and Sympathetic Excitation
during Hypercapnia Require Glutamatergic Neurotransmission
in the Retrotrapezoid Nucleus. E. Lemes, D. Zoccal. São
Paulo State Univ., Araraquara.
B433 757.8
Macrophage-Dependent Impairment of α2
Autoreceptor Inhibition of Ca2+ Currents in Sympathetic
Neurons Contributes to Hypertension in DOCA-Salt Rats. R.
Mui, R. Fernandes, J. Galligan. Michigan State Univ.
B434 757.9
N-Acetyl Cysteine Reduces Sympathetic
Activation during Acute Intermittent Hypoxia in Healthy
Human Subjects: Implications for Obstructive Sleep Apnea.
N. Jouett, G. Moralez, D.W. White, J. Tian, M.L. Smith, M.C.
Zimmerman, P.B. Raven. Univ. of North Texas Hlth. Sci. Ctr.,
Univ. of Illinois Chicago and Univ. of Nebraska Med. Ctr.
B435 757.10 BDNF/TrkB Antagonism Attenuates the
Hypertensive and Sympatho-excitatory Response to ICV
Administration of Angiotensin II in Male Sprague-Dawley Rats.
B.K. Becker, H. Wang, I.H. Zucker. Univ. of Nebraska Med. Ctr.
B436 757.11 Sympathetic Overactivity Contributes to the
Pathogenesis of Non-alcoholic Fatty Liver Disease during DietInduced Obesity. C. Hurr, H. Simonyan, C.N. Young. George
Washington Univ.
B437 757.12 Acute Alcohol Consumption Blunts the Muscle
Sympathetic Nerve Activity Response to Mental Stress in
Humans. I.T. Fonkoue, B. Gervais, Q. Chen, J.R. Carter.
Michigan Technol. Univ.
B438 757.13 Diminished Intracellular Calcium in the
Hypothalamic Paraventricular Nucleus Augments Neuronal
Excitability and Sympathetic Nerve Activity. R.A. Larson, A.D.
Chapp, Z. Cheng, Z. Shan, Q-H. Chen. Michigan Technol.
Univ. and Univ. of Central Florida.
B439 757.14 High Salt Challenge Augments Expression
of Proinflammatory Cytokines and Contributes to Elevated
Neuronal Activity in the Hypothalamic Paraventricular
Nucleus. F. Zhu, R.A. Larson, P. Shi, N. Li, Q. Chen, Z. Shan.
Michigan Technol. Univ., Cedars-Sinai Med. Ctr. and Virginia
Commonwealth Univ.
758. INTEGRATED RESPONSES TO HYPOXIA
AND DISEASE
Poster
Exhibit Halls A-D
B440 758.1
EETs Oppositely Regulate Pulmonary and
Systemic Pressure in Hypoxia. S. Kandhi, J. Qin, G. Froogh, N.
Alruwaili, M.S. Wolin, A. Huang, D. Sun. New York Med. Col.
B441 758.2
The Effects of Remifentanil on the
Cardiorespiratory Responses to Severe Arterial Hypoxia in
the Rabbit. A.W. Quail, D.B. Cottee, J.M. Johnstone, S.W.
White. Fac. of Hlth. and Med., Univ. of Newcastle, Australia
and Hunter Med. Res. Inst., Newcastle.
B442 758.3
Hypertension
Impairs
Peripheral
and
Cerebrovascular Reactivity to Isocapnic Hypoxia in Humans.
I.A. Fernandes, M.O. Campos, D.E. Mansur, J.D. Mattos,
M.P. Rocha, A.C.L. Nóbrega. Fluminense Fed. Univ., Brazil.
B443 758.4
Positive Airway Pressure Therapy Improves
Nocturnal Beat-to-Beat Blood Pressure Reactivity in Patients
with Obesity Hypoventilation Syndrome. J.R. Carter, I.T.
Fonkoue, D. Grimaldi, L. Emami, D. Gozal, B. Mokhlesi.
Univ. of Chicago and Michigan Technol. Univ.
239
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PHYSIOLOGYSUNDAY
B444 758.5
Obstructive Sleep Apnea Impairs Insulin
Resistance in Metabolic Syndrome Patients with Normal
Levels of Glucose. F.X. Cepeda, S. Rodrigues, A.C.B. DutraMarques, J.C. Carvalho, E. Toschi-Dias, C.P. Jordão, M.U.
Rondon, M.J.N.N. Alves, G. Lorenzi-Filho, I.C. Trombetta.
Heart Inst (InCor)., Sch. of Phys. Educ. and Sports, Univ. of
São Paulo and Univ. Nove de Julho, São Paulo.
B445 758.6
Effects of Acute Hypoxia on Human Adipose
Tissue Lipoprotein Lipase Activity and Lipolysis. B. Mahat, É.
Chassé, J-F. Mauger, P. Imbeault. Univ. of Ottawa.
759. INTERMITTENT HYPOXIA/OXIDATIVE STRESS
Poster
Exhibit Halls A-D
B446 759.1
Acute Effects of Intermittent Hypoxia on LeptinMediated Increases in Adiponectin Expression. C. Becari, K.R.
Somers, K. Polonis, M.A. Pfeifer, S. Prachi. Mayo Clin.
B447 759.2
Contrasting Effects of Acute versus Chronic
Intermittent Hypoxia on Leptin Secretion in Differentiated
Human Preadipocytes. K.R. Somers, C. Becari, K. Polonis, P.
Singh. Mayo Clin.
B448 759.3
Cardioprotective
Intermittent
Hypoxia
Conditioning Induces Glyoxalase-1 in Rat Left Ventricle.
A. Ramani, G.F. Scott, A.G. Williams; Jr., M-G. Ryou, R.T.
Mallet. Univ. of North Texas Hlth. Sci. Ctr., Wiley Col., TX and
Tarleton State Univ., Fort Worth.
B449 759.4
Beneficial Effects of Physical Training on the
Vascular Dysfunction Induced by Intermittent Hypoxia during
Apnea. E.J-C. Esteve, Z. El Dirani, E. Lemarie, A. Daher, W.
Joumaa, G. Faury. Univ. Grenoble Alpes, France and Univ.
Libanaise, Lebanon.
B450 759.5
The Effects of Intermittent Hypoxia on the
Vasculature and Carotid Baroreflex Regulation. J.C. Tremblay,
L.M. Boulet, M.M. Tymko, G.E. Foster. Sch. of Hlth. and
Exercise Sci., Univ. of British Columbia Okanagan.
760. SCHOLANDER AWARD COMPETITION
Poster
Exhibit Halls A-D
B451 760.1
Mechanisms
Underlying
Differential
Responses to the Neuropeptide Allatostatin-C in the Cardiac
Ganglion of the Lobster, Homarus americanus M. Stanhope,
T.J. Lameyer, D.N. Shea, M. Chi, M.G. Pascual, D.J. Schulz,
A.E. Christie, P.S. Dickinson. Bowdoin Col., ME, Univ. of
Hawai’i at Manoa and Univ. of Missouri-Columbia.
B452 760.2
Physiology and Structure of Motion-Sensitive
Neurons in the Dragonfly Visual System. B.G. Shapiro. Union
Col., NY.
B453 760.3
Structure and Function of Dragonfly LoomingSensitive Neurons. C. Slugaski. Union Col., NY.
B454 760.4
Heart Rate Response to Anthropogenic
Disturbance in the Red-Eared Slider. K.L. Florimon, C.L.
Williams. Univ. of California, Irvine.
240
B455 760.5
Prolactin and Extracellular Osmolality Regulate
Branchial clc2c Expression in Tilapia. P.L.K. Keith, B.L. Hunt,
M. Inokuchi, Y. Yamaguchi, A.P. Seale, D.T. Lerner, E.G.
Grau, J.P. Breves. Skidmore Col.,NY, Univ. of Tokyo and Univ.
of Hawaii, Kaneohe and Honolulu.
B456 760.6
Increases in Thyroid Hormone-Mediated
Plasma Glucose Does Not Stimulate Insulin Secretion in
Prolonged-Fasting Northern Elephant Seal Pups. L.J. Horin,
B. Martinez, D.E. Crocker, R. Ortiz. Pitzer Col., CA, Univ. of
California, Merced and Sonoma State Univ.
B457 760.7
High Glucose-Mediated Oxidative Stress
Impairs Vasodilation of Small Resistance Skeletal Muscle
Arteries from Mourning Doves (Zenaida macroura) Z.S.
Ahmed, C.L. Jarrett, J.J. Faust, K.L. Sweazea. Arizona
State Univ.
B458 760.8
Glycogen Synthesis from Lactate in Skeletal
Muscle of the Painted Turtle In Vitro. D. Wang, C.A. Hill, C.E.
Grombka-Murphy, J.S. Fisher, D.E. Warren, K. Nguyen.
Saint Louis Univ.
B459 760.9
Effects of Jumping on Grasshopper Muscle
Carbohydrate Levels. A.A. MacDonald, S. Azher, S.D.
Kirkton. Union Col., NY.
B460 760.10 Effect of Electrical Stimulation on Grasshopper
Jumping Muscle. A.A. Yazdani, R.C. Broadwell, S.D. Kirkton.
Union Col., NY.
B461 760.11 The Ontogenetic Scaling of Metabolic Rate in
Wing-Polymorphic Gryllus firmus A.D. Cooper, R.J. Schilder.
Penn State.
B462 760.12 Age-Related Decline of Anoxia Tolerance in
Adult Drosophila Melanogaster J.C. Sargent, J.B. Campbell,
J.F. Harrison. Sch. of Life Sci., Arizona State Univ., Tempe.
B463 760.13 Geographic Distribution and Functionality of
Cuticular Hydrocarbons in Drosophila athabasca T. Harvey, R.
Yukilevich. Union Col., NY.
B464 760.14 Benefits of Being Small? The Scaling of Flight
Performance in Stingless Bees and Size-Dependent Scaling of
Insect Flight Metabolism. M. Duell, J.F. Harrison. Sch. of Life
Sci., Arizona State Univ.
B465 760.15 Using Confocal Imaging to Understand
the Effect of Atmospheric Oxygen on Insect Respiratory
Systems. G. Gstrein, K. Arthur, G. Parker, J. Friedman, J.
VandenBrooks. Midwerstern Univ., AZ.
B466 760.16 Metabolic and Genetic Implications of Survival
in Anoxic Drosophila J.B. Campbell, J.F. Harrison. Arizona
State Univ. Sch. of Life Sci.
B467 760.17 Stellate and Pyramidal Neurons in Goldfish
Telencephalon Respond Differently to Anoxia and GABA
Receptor Inhibition. N. Hossein-Javaheri. Univ. of Toronto.
B468 760.18 The Anoxic Reduction of Mitochondrial ROS
Production Leads to Increased GABAergic Interneuron Activity
and Electrical Suppression in Turtle Cerebral Cortex. P.
Hawrysh, D. Hogg, L. Buck. Univ. of Toronto.
B469 760.19 Amino Acids as Fates of Anoxia-Induced
Lactate Loads in the Painted Turtle. C.A. Hill, K.E. Yarasheski,
D.E. Warren. Saint Louis Univ. and Sch. of Med., Washington
Univ. St. Louis.
B470 760.20 Species Differences in Gastrointestinal Tract
Glucose Transporters between Rainbow Trout (Oncorhynchus
mykiss) and Nile Tilapia (Oreochromis niloticus) M.
Subramaniam, L.P. Weber, J.C. Ching, C.B. Enns, A.B.
Kilgour, M.D. Drew, M.E. Loewen. Univ. of Saskatchewan.
SUNDAYPHYSIOLOGY
B471 760.21 Molecular Phenotypes of Gills from Resident
Marine versus Landlocked Freshwater Three-Spined
Sticklebacks (Gasterosteus aculeatus) J. Li, D.M. Paguio, D.
Kültz. Univ. of California, Davis.
B472 760.22 The Effect of Intracellular pH on Myocardial
Calcium Sensitivity in the Anoxia-Tolerant Painted Turtle. C.E.
Fanter, D.E. Warren, K.S. Campbell. Saint Louis Univ. and
Univ. of Kentucky.
B473 760.23 Soluble Adenylyl Cyclase Senses Alkalosis in
Epithelial Base-Secreting Cells. J.N. Roa, M. Tresguerres.
Scripps Instn. of Oceanography.
B474 760.24 Control of Lung Ventilation after Extended
Disuse Caused by Overwintering Submergence in the Bullfrog.
J. Santin, L. Hartzler. Wright State Univ.
B475 760.25 Aquatic Hypercapnia and Aerial Excretion
of CO2 in Air-Breathing Fishes. C. Jew, M. Thomsen, M.
Bayley, J.W. Hicks. Univ. of California, Irvine and Aarhus
Univ., Denmark.
B476 760.26 Elevated Carbon Monoxide Production in
Marine Mammals. M.S. Tift, J. St. Leger, T. Leuker, P.J.
Ponganis. Scripps Instn. of Oceanography and SeaWorld,
La Jolla.
B477 760.27 Seasonal Cold Exposure Modulates Metabolic
Phenotype and Mitochondrial Function in Obese GoldenMantled Ground Squirrels. A.B. Heim, M.A. Lashbrook, S.A.
Rosales, J.B. Wakefield, G.L. Florant, A.J. Chicco. Colorado
State Univ.
B478 760.28 Deiodinase Type 3 Methylation Increases
in Response to Thyroid Stimulating Hormone in a Fasting
Adapted Mammal. B. Martinez, N. Gemmell, D.E. Crocker,
R.M. Ortiz. Univ. of California Merced, Univ. of Otago, New
Zealand and Sonoma State Univ.
B479 760.29 Glyceroporin HC-9 in the Freeze Tolerance
Mechanism of Cope’s Gray Treefrogs. B. Stogsdill, J. Frisbie,
P.T. Tsou, D. Goldstein. Wright State Univ.
B480 760.30 Effects
of
Hyperosmotic
Stress
on
Cellular Proteome and Phenotype of Tilapia (Oreochromis
mossambicus) OmB Cells. T.N. Wiegers, D. Kültz. Univ. of
California, Davis.
761. ACUTE EXERCISE RESPONSES
Poster
Exhibit Halls A-D
B481 761.1
Acute Effect of Ischemic Preconditioning on
V?O2max and V?O2 Kinetics at Supramaximal Intensity in
High-Level Runners: A Randomized Placebo- and NoceboControlled Study. J.L. Sabino-Carvalho, T.R. Lopes, T. ObeidFreitas, T.H.N. Ferreira, J.E. Succi, A.C. Silva, B.M. Silva.
Fed. Univ. of São Paulo and Olympic Ctr. of Res. and Training,
São Paulo.
B482 761.2
Exercise Pressor Reflex Response to Static
and Dynamic Skeletal Muscle Stretch. M. Venturelli, E. Cè,
E. Limonta, S. Rampichini, A.V. Bisconti, M. Devoto, F.
Esposito. Univ. of Milan.
B483 761.3
Comparison of Stress Response Pathways in
Male and Female Athletes during Ultra-marathon Events. W.
DeNeen, A.B. Jones. Northeastern State Univ.
B484 761.4
Handgrip Exercise Increases Platelet-Bound
BDNF in an Intensity-Dependent Manner. J.J. Walsh, R.F.
Bentley, M.E. Tschakovsky. Sch. of Kinesiol. and Hlth.
Studies, Queen’s Univ., Canada.
B485 761.5
Persistent Augmentation of the Blood Pressure
and Heart Rate Responses to Dynamic Exercise in Rats with
Chronic Bilateral Femoral Artery Occlusion. J.M. Kuczmarski,
K. Unrath, G.D. Thomas. Penn State Col. of Med.
B486 761.6
A Novel Model of Weightlifting in Mice: Signaling
and Gene Transcription Responses in Skeletal Muscle. D. Cui,
B. Lewellen, R. Wilson, M. Zhang, Z. Yan. Univ. of Virginia,
East China Normal Univ., Shanghai.
B487 761.7
Acute Effects of Isometric Handgrip Exercise
on Blood Pressure and Heart Rate Variability. B. Locke. San
Francisco State Univ.
B488 761.8
Power Reserve at the Limit of RampIncremental Exercise Is Affected by Incrementation Rate. M.J.
Davies, A.P. Benson, K.M. Birch, H.B. Rossiter, C. Ferguson.
Sch. of Biomed. Sci., Univ. of Leeds and LA BioMed Res. Inst.
at Harbor-UCLA Med. Ctr.
B489 761.9
Investigation Into Effects of Supplementary
O2 on Tissue Oxygenation during Isometric Handgrip in the
Ipsilateral and Contralateral Limb in Young (Y) and Older
(O) Men Using Near Infra Red Spectroscopy (NIRS) R.T.
Junejo, C.J. Ray, S.J.E. Lucas, J.M. Marshall. Univ. of
Birmingham, U.K.
B490 761.10 Rapid Onset Vasodilation in the Leg Is Greater
in Habitual Endurance Runners. C. Coolbaugh, E. Bush, S.
Sabin, B. Scott, B. Damon, T. Towse. Vanderbilt Univ.
B491 761.11 Is a 90 Min Recovery Period following Fatiguing
Handgrip Exercise Enough to Ensure Maximal Performance
during a Critical Impulse Test or Incremental Exercise Test?
A.M. Fenuta, M.E. Tschakovsky. Queen’s Univ., Canada.
B492 761.12 Effects of High Intensity Interval Exercise on
Peripheral Blood Flow and Muscle Tissue Oxygenation. S.K.
Neeley, M.J. Luetkemeier, J. Davis. Alma Col., MI.
B493 761.13 Endothelial Dysfunction Predicts Systolic
Blood Pressure Slope during Whole Body Maximal Exercise in
Patients with Chronic Kidney Disease. R.M. Downey, P. Liao,
E.C. Millson, A.A. Quyyumi, J. Park. Emory Univ. Sch. of
Med., DVA Med. Ctr., Decatur and Emory Univ. Rollins Sch. of
Publ. Hlth.
B494 761.14 Effects of Hypoxia with Matched Convective
O2 Delivery on Fatigue and O2 On-Kinetics in Canine Skeletal
Muscle In Situ. B.S. Ferguson, J.R. McDonald, F. Mowry,
Y. Sun, L. Rasica, S. Porcelli, M.C. Hogan, B. Grassi, B.
Gladden. Univ. of Illinois at Chicago, Auburn Univ., Ministry
of Educ., Shanghai, NRC, Univ. of Udine, Univ. of Milan
and UCSD.
B495 761.15 Oxygen Uptake Efficiency Slope in Patients
with Metabolic Syndrome and Obstructive Sleep Apnea.
J.C. Carvalho, F.X. Cepeda, S. Rodrigues, A.C.B. DutraMarques, E. Toschi-Dias, M.U.P.B. Rondon, M-J.N.N. Alves,
A.M.F.W. Braga, G. Lorenzi-Filho, I.C. Trombetta. Heart Inst.
(InCor), Univ. of São Paulo and UNINOVE, São Paulo.
B496 761.16 Prediction of Mountain Marathon Performance
with Anaerobic Capacity. M.J. Rogers, L.J. Rietchel, P.K.
Singh, I.J. Foster, A.L. Wookey, M.D. White. Simon Fraser
Univ., Canada.
B497 761.17 Expiratory
Flow
Limitation,
Dynamic
Hyperinflation, and Locomotor Power and Fatigue. J. Cunha,
P. Benedict, A. Domingo, F.W. Kolkhorst, H.B. Rossiter, D.T.
Cannon. Sch. of Exercise & Nutr. Sci., San Diego State Univ.
and LA BioMed at Harbor-UCLA Med. Ctr.
241
S
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PHYSIOLOGYSUNDAY
B498 761.18 Is There a Relationship between Pulmonary
Capillary Blood Volume and Intrapulmonary Arteriovenous
Anastomosis Recruitment during Exercise? V. Tedjasaputra,
S.É. Collins, T.L. Bryan, S. van Diepen, M.M. Bouwsema,
M.K. Stickland. Univ. of Alberta and Covenant Hlth.,
Edmonton, Canada.
762. REDUCED GRAVITY AND
HYPERBARIC ENVIRONMENTS
Poster
Exhibit Halls A-D
B499 762.1
X-Irradiation and Simulated Microgravity
Affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain
Threshold. P. Chowdhury, N. Akel, A-J. Parsian, R. Griffin, J.
Yadlapalli, M. Dobretsov. Univ. of Arkansas for Med. Sci.
B500 762.2
Does Pulse Contour Analysis Provide a Valid
Estimate of Cardiac Output during Spaceflight? N.J. Yee, K.A.
Zuj, D.K. Greaves, R.L. Hughson. Univ. of Calgary and Univ.
of Waterloo, Canada.
B501 762.3
Elevated Inspired and End-Tidal PCO2 on the
International Space Station. R.L. Hughson, N.Yee, D. Greaves.
Schlegel-Univ. of Waterloo Res. Inst. for Aging, Canada.
B502 762.4
Sex Differences in the Cardio-metabolic and
Hormonal Responses to Long-Duration Spaceflight. R.L.
Hughson, K. Shoemaker, J. Rush, P. Arbeille. SchlegelUW Res. Inst. for Aging, Waterloo, Western Univ. and Univ. of
Waterloo, Canada and Univ. of Tours, France.
B503 762.5
Comparative Analysis of Gastrointestinal and
Bone Inflammation in Hindlimb Unloading. A. Narayanan, C.
Metzger, J. Brezicha, S. Lenfest, S. Bloomfield, H. Hogan, D.
Zawieja. Texas A&M Univ. Hlth. Sci. Ctr. and Texas A&M Univ.
B504 762.6
Lower Body Negative Pressure Decreases
Intracranial Pressure and Internal Jugular Vein Cross-Sectional
Area. W. Watkins, S. Baird, E.M. Clary, A.R. Hargens, B.R.
Macias. UCSD and Johnson Space Ctr. Cardiovasc. and
Vision Lab.
B505 762.7
Are Inert Gases Inert? Hyperbaric Nitrogen
and Hyperoxia Stimulate Singlet O2 Production in Solitary
Complex Neurons of the Dorsocaudal Medulla in Rat Brain
Slices. T. Roberts, J.B. Dean. Univ. of South Florida.
B506 762.8
Lower Body Negative Pressure Treadmill
Exercise Attenuates Simulated Space Flight-Induced
Reductions of Balance Abilities in Males but Not Females. T.R.
Macaulay, B. Macias, S.M.C. Lee, W. Boda, D.E. Watenpaugh,
A. Hargens. UCSD, Wyle Sci., Technol. & Engin. Gp., Houston,
Sonoma State Univ. and Univ. of North Texas.
B507 762.9
Intracranial Pressure Increases during
Hindlimb Suspension. H.S. Gompf, E.L. Robinson, T.M.
Hoban-Higgins, C.A. Fuller. Univ. of California, Davis.
B508 762.10 Convective and Diffusive O2 Transport
Mechanisms Mediate the Decrease in Peak Oxygen
Uptake following Long-Duration Spaceflight. C.J. Ade, R.M.
Broxterman, A.D. Moore, T.J. Barstow. Univ. of Oklahoma,
Univ. of Utah, Lamar Univ. and Kansas State Univ.
242
763. VASCULAR RESPONSES TO EXERCISE AND
ENVIRONMENTAL STRESS
Poster
Exhibit Halls A-D
B509 763.1
Prolonged Adenosine Triphosphate Infusion
and Exercise Hyperemia. J.R.A. Shepherd, M.J. Joyner, F.A.
Dinenno, T.B. Curry, S.M. Ranadive. Mayo Clin. and Colorado
State Univ.
B510 763.2
Hypercapnic
Cerebral
Vasodilation:
Contribution of Cyclooxygenase and Reactive Oxygen Species
in Healthy and Metabolic Syndrome Adults. J. Harrell, G.
Peltonen, K. LaPlante, B. Ernst, W. Schrage. Drake Univ., IA
and Univ. of Wisconsin-Madison.
B511 763.3
Repeated Moderate Heat Exposure Improves
Limb Endothelial Function in Humans. J. Cui, M. Lott, C.
Blaha, L.I. Sinoway. Penn State Hershey Heart and Vasc. Inst.
B512 763.4
Microvascular Responsiveness to Exogenous
H2S Is Similar between Normotensive and Hypertensive Adults.
J.L. Kutz, J.L. Greaney, L. Santhanam, L.M. Alexander.
Shenandoah Univ., Penn State and Johns Hopkins Univ. Sch.
of Med.
B513 763.5
Amplification
of
Endothelium-Dependent
Vasodilatory Signaling in Contracting Skeletal Muscle of
Humans: Role of Inwardly Rectifying Potassium Channels.
C.M. Hearon;Jr., G.J. Luckasen, D.G. Larson, F.A. Dinenno.
Colorado State Univ., Med. Ctr. of the Rockies Fndn. and Ctr.
for Cardiovascular Research.
B514 763.6
Effect of Prolonged Adenosine Infusion on
Resting Forearm Vasodilatory Responses and Exercise
Hyperemia. S. Ranadive, J-R.M. Shepherd, F. Dinenno, T.
Curry, M. Joyner. Mayo Clin. and Colorado State Univ.
B515 763.7
Individual Differences in Compensatory
Vasodilation Impact Exercise Performance. R.F. Bentley, J.J.
Walsh, A.M. Fenuta, P.J. Drouin, M.E. Tschakovsky. Queen’s
Univ., Canada.
B516 763.8
Endothelial Dysfunction following Prolonged
Sitting Is Mediated by a Reduction in Shear Stress. R.M.
Restaino, L.K. Walsh, T. Morishima, J.R. Vranish, L.A.
Martinez-Lemus, P.J. Fadel, J. Padilla. Univ. of MissouriColumbia and Univ. of Texas-Arlington.
B517 763.9
Vascular Responses to Hypovolemic Pressure
Challenge in Individuals with Down Syndrome. S.O. Wee,
A.J. Rosenberg, B. Kanokwan, G. Griffith, T. Baynard, B.
Fernhall. Univ. of Illinois at Chicago.
B518 763.10 Hypercapnic Responses Uncover Regional
Cerebrovascular Dysfunction and a Varying Role of
Cyclooxygenase in Young Adults with Metabolic Syndrome.
J.M. Kellawan, J.W. Harell, A. Roldan-Alzate, O. Wieben,
W.G. Schrage. Univ. of Wisconsin - Madison.
B519 763.11 Height Correction for Carotid Blood Pressure
Measurement during Positional Changes Is Important to
Account for Gravitational Effects When Assessing Arterial
Stiffness. A.J. Rosenberg, D.W. White, E.C. Schroeder,
T.I. Hilgenkamp, B. Fernhall, T. Baynard. Univ. of Illinois
at Chicago.
B520 763.12 The
Role
of
Prolonged
Adenosine
Triphosphate Infusion on Rapid Onset Vasodilation. G. Dillon,
J-R. Shepherd, F. Dinenno, T. Curry, M. Joyner, S. Ranadive.
Mayo Clin. and Colorado State Univ.
SUNDAYPHYSIOLOGY
B521 763.13 Heat Acclimation and Cross-Tolerance:
Changes in the Mitochondrial Proteome. M. Horowitz, E.
Smeir, G. Gerstenblith. The Hebrew Univ. of Jerusalem and
Johns Hopkins Univ.
B522 763.14 Effect of High-Intensity Interval Training on
Endothelial Function in Older Postmenopausal Women: A
Randomized Controlled Trial. J-K. Yoo, M-H. Hwang, H-K. Kim,
E-L. Hwang, E.M. Handberg, D. Christou. Univ. of Florida.
B523 763.15 Transiently
Augmented
Endothelium
Dependent Vasodilatory Capacity following Repeated 6-Hour
Air Dives. R.G. Morgan, E. Bergeron, B.E. Shykoff, J.P.
Florian. Navy Exptl. Diving Unit, Panama City, FL.
B524 763.16 Tempol Augments the Blunted Cutaneous
Microvascular Thermal Reactivity in Healthy Young African
Americans. C. Hurr, J.C. Patik, K.M. Christmas, R.M.
Brothers. George Washington Univ., Univ. of Texas at Arlington
and Univ. of Texas at Austin.
B525 763.17 Long-Term Endurance Exercise Training
Ameliorates Conduit Artery Retrograde and Oscillatory Shear
in Older Adults. A.C. Schneider, K. Ueda, D.P. Casey. Univ.
of Iowa.
B526 763.18 Endothelin-1 Modulates Methacholine-Induced
Cutaneous Vasodilation but Not Sweating in Young Human
Skin. L. Halili, M.S. Singh, N. Fujii, L.M. Alexander, G.P.
Kenny. Univ. of Ottawa and Penn State.
B527 763.19 Elevated Extracellular Potassium Prior to
Muscle Contraction Reduces Exercise Hyperemia in Humans.
J.D. Terwoord, C.M. Hearon; Jr., G.J. Luckasen, D.G. Larson,
M.J. Joyner, F.A. Dinenno. Colorado State Univ., Med. Ctr. of
the Rockies Fndn., PVHS, Loveland, CO and Mayo Clin.
B528 763.20 Passive Heat Stress Prevents Endothelial
Ischemia-Reperfusion Injury in Young Healthy Humans. V.E.
Brunt, A.T. Jeckell, B.R. Ely, M.J. Howard, M.A. Francisco,
C.T. Minson. Univ. of Oregon.
B529 763.21 Cutaneous Blood Flow during Intradermal
Exogenous Nitric Oxide Administration in Young and Older
Adults: Roles for Cyclooxygenase and Calcium-Activated
Potassium Channels? N. Fujii, M.S. Singh, C.T. Minson, V.E.
Brunt, P. Boulay, R.J. Sigal, G.P. Kenny. Univ. of Ottawa, Univ.
of Oregon, Univ. of Sherbrooke and Univ. of Calgary, Canada.
B530 763.22 The Impact of Acute Isocapnic Hypoxia on
Reactive Hyperemia in Young, Healthy Humans. E.A. Kelsch,
J.L. Keller, A.R. Crecelius. Univ. of Dayton.
B531 763.23 Orthotopic versus Ectopic Tumor Perfusion
during Exercise: Implications for Host Tissue Vasoreactivity.
E. Garcia, V. Becker, E.M. Gittemeier, A.B. OpokuAcheampong, D. McCullough, B.J. Behnke. Kansas State
Univ. and Edward Via Col. of Osteo. Med., Auburn, AL.
B532 763.24 Aging Slows Vasoconstriction Dynamics
in Skeletal Muscle Resistance Vessels. E.M. Gittemeier,
T.J. Ericson, R. Verma, P. Ghosh, E. Garcia, A. OpokuAcheampong, B.J. Behnke. Kansas State Univ., Univ. of
Florida and Florida State Univ.
B533 763.25 Blunted Arterial Blood Pressure Responses to
Whole-Body Cold Stress in Individuals with Multiple Sclerosis.
D.R. Allen, M.R. Huang, E.M. Frohman, S.L. Davis. So.
Methodist Univ., Univ. of Texas at Arlington and Univ. of Texas
Southwestern Med. Ctr.
B534 763.26 Extracellular Matrix Affects Endothelial Cell
Attachment under Shear Flow. Y-F. Chiu, B. Huang. Kaohsiung
Med. Univ., Taiwan.
B535 763.27 Aerobic
Exercise
Dampens
Acute
Hypertension-Induced Vascular Oxidative Stress. A.T.
Robinson, I.S. Fancher, J-T. Bian, M.M. Ali, V. Sudhahar, M.
Ushio-Fukai, T. Fukai, I. Levitan, S.A. Phillips. Univ. of Illinois
at Chicago Col. of Med.
B536 763.28 Effects of Eccentric Exercise-Induced Muscle
Damage on Endothelial Function and Skeletal Muscle
Microvascular Deoxygenation. J.T. Caldwell, C.J. Ade, C.D.
Black, G.C. Wardlow, S.F. Maggard, P.A. Branch, R.N. Hardy,
A.T. Quarshie. Univ. of Oklahoma.
B537 763.29 Regular Exercise Reduces Endothelial and
Whole Artery Stiffness in Western Diet-Fed Female Mice.
J. Padilla, F.I. Ramirez-Perez, B. Bostick, A.R. Aroor,
C. Manrique, L.A. Martinez-Lemus, J.R. Sowers. Univ.
764. WHAT DO BOTH MITOCHONDRIAL PROTEIN
TURNOVER AND MITOCHONDRIAL FUNCTION
TELL US ABOUT EXERCISE AND AGING?
Poster
Exhibit Halls A-D
B538 764.1
Effect of Partial Denervation Mitochondrial ROS
Generation in Skeletal Muscle. N. Pollock, C.A. Staunton, A.
Vasilaki, A. McArdle, M. Jackson. Univ. of Liverpool.
B539 764.2
Exercise Training Induced Regulation of
Muscle Mitochondrial Dynamics. D.K. Fix, J.P. Hardee, S. Gao,
K.L. Hetzler, J.A. Carson. Univ. of South Carolina.
B540 764.3
Parkin-Mediated Mitophagy in Skeletal Muscle
with Aging and Exercise. C. Chen, D. Hood. Sch. of Kinesiol.
and Hlth. Sci., York Univ., Canada.
B541 764.4
Anabolic Response to Exercise Is Not Limited
in Older Adults Despite Lower Mitochondrial Respiratory
Capacity Compared to Young. I. Lanza, A. Lalia, S. Dasari, M.
Robinson, H. Abid, D. Morse, K. Klaus. Mayo Clin.
B542 764.5
Evidence for a Novel Role for eNOS in
the Regulation of Hepatocellular Mitophagy. R. Sheldon,
E.M. Morris, M.A. Linden, G.M. Meers, J.P. Thyfault, M.H.
Laughlin, R.S. Rector. Univ. of Missour-Columbiai, Harry S
Truman Mem. VA Hosp. and Univ. of Kansas Med. Ctr.
765. CARDIOVASCULAR ENDOCRINOLOGY,
INCLUDING RAAS
Poster
Exhibit Halls A-D
B543 765.1
Resistin Enhances the Central Effects of
Leptin on Renal Sympathetic Nerve Activity. H. Habeeballah,
N. Alsuhaymi, M. Stebbing, T. Jenkins, E. Badoer. Sch. of
Med. Sci., RMIT Univ., Melbourne.
B544 765.2
Effects of Mirabegron, a β?-Adrenergic
Receptor Agonist, On metabolic and Cardiovascular
Parameters in Obese Mice. A. Zanesco, C.P. Valga da silva,
F.B. Calmasini, E.C. Alexandre, T. Candido, F.T. Monica, M.A.
Delbin. UNESP, Rio Claro and UNICAMP, Campinas, Brazil.
243
S
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PHYSIOLOGYSUNDAY
B545 765.3
The Inwardly Rectifying Potassium Channel
GIRK4 Plays a Role in Aldosterone Production in the Mouse
Adrenal Cortex. I. Hardege, K.M. O’Shaughnessy. Univ.
of Cambridge.
B546 765.4
Ventricular
Disfunction
Induces
Morphofunctional Changes in Adrenal Glands. T.R. de
Andrade, J. Silva, L. Souza, C. Jordão, T. Ferreira, C. Negrao,
P. Brum, M.C. Irigoyen, S. Lacchini, M.J. Alves. Heart Inst.,
Biomed. Sci. Inst. and Sch. of Phys. Educ. and Sport, Univ. of
São Paulo.
B547 765.5
Aldosterone Acutely Enhances Coronary Artery
Contractile Responsiveness without Inducing Endothelial
Dysfunction. H.M. Cleeton, A.I. Meuth, S.B. Bender. Univ. of
Missouri-Columbia and Harry S. Truman Mem. Veterans Hosp.
B548 765.6
Intermittent Hypoxia Upregulates Angiotensin
II Generating Pathways in Human Preadipocytes. C. Becari, P.
Singh, K. Polonis, V.K. Somers. Mayo Clin.
B549 765.7
Characterization of 125-I-Angiotensin (17) Binding to Mouse Forebrain and Liver and Rat Liver. F.F.
Conti, A.C. Linares, L.E. Couling, M. Morris, K. De Angelis,
R. Speth. Univ. Nove de Julho, São Paulo, Nova Southeastern
Univ. and Georgetown Univ.
B550 765.8
Captopril Suppresses Polybrominated Diphenyl
Ether-Induced Pressor Responses and Upregulation of Raas
Gene Markers Nr3c2 and Sgk1 Under Salt Loading in Rats.
J.E. Lindner, R. Gutierez, A. Ramirez, K. Spurgin, M. Valdez,
D. Platt, M. Curras-Collazo. Univ. of California, Riverside.
B551 765.9
Differential Agonistic Activities of Angiotensin
Peptide Analogs. R.C. Speth, E. Sturchler, P. McDonald. Nova
Southeastern Univ. and The Scripps Res. Inst., Jupiter, FL.
B552 765.10 Regulation of the Cardiac Fibroblast
Transcriptome by Aldosterone In Vivo. M. Syed, J.P. Ball, L.L.
Yanes, D.G. Romero. Univ. of Mississippi Med. Ctr.
B553 765.11 Nur77 Inhibits Isoproterenol-Induced Cardiac
Fibrosis through Upregulation of Relaxin-3Z-F.
Guo,
G.
Zhang, X. You, B. Yi, F. Cheng, J. Sun. Thomas Jefferson Univ.
766. PANCREATIC HORMONES, GLUCOSE
HOMEOSTASIS, AND DIABETES
Poster
Exhibit Halls A-D
B554 766.1
Effect of Chronic Stress and Aerobic Exercise
on Glycemic Control in Rats. F.K. Marcondes, A. Sanches,
R. Costa, D.E. Casarini, T.S. Cunha. FOP - UNICAMP,
Piracicaba, Fed. Univ. of São Paulo, UNIFESP and San Jose
dos Campos, Brazil.
B555 766.2
Mitogen-Inducible Gene 6 Accelerates the
Progression to Diabetes by Inhibiting EGFR-Mediated Repair
Mechanisms. K.M. Fong, P.T. Fueger. Indiana Univ. Sch.
of Med.
B556 766.3
Diabetes Mellitus Influences the Pattern of
Distribution of Irisin in Pancreatic Islet Cells. E. Adeghate, C.
D’Souza, A.M. Al Harthi. Col. of Med. & Hlth. Sci., United Arab
Emirates Univ.
B557 766.4
Mouse SERCA2b Is Critical in Compensatory
Response to High Fat Diet by Maintaining Pancreatic β Cell
Proliferation. X. Tong, T. Kono, E. Anderson-Baucum, G. Shull,
C. Evans-Molina. Indiana Univ. Sch. of Med., Univ. of Cincinnati
Col. of Med. and Herman B Wells Ctr. for Pediat. Res., Indianapolis.
244
B558 766.5
Diet-Induced Obesity Increases Hepatic Mig6
Expression and Attenuates EGFR Signaling. A.J. Lutkewitte, P.T.
Fueger, Y-C. Chen, J.L. Hansen. Indiana Univ. Sch. of Med.
B559 766.6
Effect of Diabetes-Associated Metabolic Factors
on Placental Growth Factor in Skeletal Muscle Cells. F. Rouf, P.G.
Lloyd. Oklahoma State Univ.
B560 766.7
Paracrine GABA and Insulin Restrain Pancreatic
α-Cell Proliferation in Islets of Langerhans. A.L. Feng, Y-Y. Xiang,
L. Gui, Q. Feng, W-Y. Lu. Western Univ., Canada.
B561 766.8
Beta Cells Deletion of the Angiotensin-II Type
1a Receptor Differentially Influences Insulin Levels in Male and
Female Mice. H. Chodavarapu, E. Lazartigues. LSU Hlth. Sci.
Ctr., New Orleans.
B562 766.9
Regional Differences of Pancreatic Islet Area
and Beta Cell Density in Obese and Lean Zucker Rats. G. Goudy,
S. Asano, H. Hoskinson, M. Dawson, M. Breit, M. Olfert, J.C.
Frisbee, P.D. Chantler, S. Alway, R. Bryner. West Virginia Univ.
B563 766.10 Proinsulin C-Peptide Prevents VEGF Release
from ARPE-19 Cells: A Novel Signaling Mechanism. G.R. Kolar,
G.L.C. Yosten. Saint Louis Univ.
B564 766.11 HDSC1 Increases Functional β-Cell Mass. C.
Draney, A. Hobson, J. Tessem. Brigham Young Univ.
B565 766.12 Monomeric Cocoa Procyanidins Enhance
Functional β-Cell Mass. T. Rowley, B. Bitner, M. Ballard, A.T.
Smithson, A.P. Neilson, J.S. Tessem. Brigham Young Univ. and
Virginia Tech.
B566 766.13 Aged Islets Are Refractory to Nkx6.1 Mediated
β-Cell Proliferation. B. Wright, K. Garland, C. Tidwell, S. Kang,
J.S. Tessem. Brigham Young Univ.
B567 766.14 A Novel Role for the PKG-Encoding foraging
Gene in the Fly ‘Pancreas’ of Drosophila melanogaster B.N.
Hughson, A. Vesterberg, M.B. Sokolowski. Univ. of Toronto.
B568 766.15 The Effects of Hyperglycemia on Insulin
Resistance in a Drosophila model of Alzheimer’s Disease. D.
Cline, B. Paddock. Arcadia Univ. Col. of Arts and Sci.
B569 766.16 Improvement of the Adipokines Profile and
Insulin Resistance in Metabolic Syndrome Patients Induced by
Galantamine Activation of Cholinergic Pathway. C.T. Sangaleti,
F.O. Costa, T.L. Moraes, M.C. Irigoyen, L.A.T. Bortolotto, H.F.
Lopes, V. Pavlov, K. Tracey, F.M. Consolim-Colombo. Univ. of
São Paulo, State Univ. of Paraná Midwest, Univ. Nove de Julho,
São Paulo and Feinstein Inst. for Med. Res., Manhasset, NY.
B570 766.17 GLP-1-Producing Neurons in the Control of
Glucose Homeostasis and Insulin Sensitivity. X. Shi, S. Chacko,
D. Li, F. Li, X. Guan. Baylor Col. of Med., Binzhou Med. Univ.
Hosp., China and Univ. of Texas MD Anderson Cancer Ctr.
B571 766.18 Nutritional Status Affects Expression of Insulin
Receptor mRNA in a Tissue Specific Manner in Channel Catfish.
A. Leiker, P. Evans, B. Watkins, Y. Kobayashi. Fort Hays
State Univ.
767. AGING AND MUSCLE FUNCTION
Poster
Exhibit Halls A-D
B572 767.1
Effect of Dihydrotestosterone Treatment on
Young and Elderly Mice Skeletal Muscle. O. Wendowski. Univ.
of East Anglia, U.K.
SUNDAYPHYSIOLOGY
B573 767.2
Caveolin-2 Enhances Longevity and Induces
Stress Adaptation in C. elegans M.D. Mehta, E.D. Mehta,
J.M. Schilling, E. Shi, H.N. Fridolfsson, D.M. Roth, H.H.
Patel. UCSD.
B574 767.3
Calcium/Calmodulin-Dependent
Protein
Kinase II Delta – Does Ageing Mirror Disease in the
Cardiovascular System? C. McCluskey, H. Salleh, S. Currie.
Univ. of Strathclyde, U.K.
B575 767.4
Impact
of
Aging
on
Fatigue
and
Corticomotoneuronal Excitability during Small Muscle Mass
Exercise. J.C. Weavil, S.K. Sidhu, T.S. Mangum, T.S.
Thurston, R.S. Garten, R.S. Richardson, M. Amann. Univ.
of Utah.
B576 767.5
Rejuvenation
of
Aged
Neuromuscular
Junctions by Exposure to a Young Systemic Environment. E.J.
Shin, A. Wagers, Y.C. Jang. Georgia Tech and Harvard Univ.
768. CALCIUM AND MUSCLE CONTRACTILITY
Poster
Exhibit Halls A-D
B583 769.3
Exercise Induces Skeletal Muscle Heat Shock
Protein Expression Independent of Dietary Macronutrient
Content. A. Von Schulze, T.A. Gunnels, J-H.M. Schriefer,
S-R. Lee, J.J. MacDonnchadh, R.K. Buddington, K.K.
Buddington, M. van der Merwe, H.J. Sable, R.J. Bloomer,
C.D. Touchberry. Univ. of Memphis and New Mexico State Univ.
B584 769.4
Heat Shock Factor Activation in Skeletal
Muscle following Lengthening Contractions. E. Pollock-Tahiri,
M. Locke. Univ. of Toronto.
B585 769.5
Heat Shock Proteins as Markers of ContractionInduced Muscle Damage. E. Pollock-Tahiri, M. Locke. Univ.
of Toronto.
770. MUSCLE DYSFUNCTION IN DIABETES
Poster
Exhibit Halls A-D
B577 768.1
Calcium-Dependent Sliding of Actin Thin
Filaments Isolated from Hearts with Obstructive Hypertrophic
Cardiomyopathy and Donor Controls Does Not Differ. S. Beck
Previs, S.M. Day, M.J. Previs, J.P. Snyder. Saint Michael’s
Col., Univ. of Vermont and Univ. of Michigan.
B578 768.2
Rewarming Shock Disrupts Intracellular Ca2+
Homeostasis and Contractility in Cardiomyocytes. T. Hoang,
N. Schaible, Y.S. Han, G. Arteaga, T. Tveita, G. Sieck. Mayo
Clin. and Arctic Univ. of Norway.
B579 768.3
Jagged-1 Enhances CaSR-Induced Increase
in [Ca2+]cyt by Promoting Recruitment of STIM2 to ER-PM
Junctions. S. Song, K.M. McDermott, A. Makino, J.X-J. Yuan.
Univ. of Arizona.
B580 768.4
Drugs That Inhibit the Sarcoplasmic Reticulum
Ca2+ ATPase (SERCA) and Prevention of Breast Cancer Cell
Proliferation. M. Loulousis, S.L. Krager, Y.L. Darcy, S.A.
Tischkau, J.A. Copello. So. Illinois Univ. Sch. of Med.
B586 770.1
Obesity Distinctly Influences Cardiac Function
and Molecular Responses to Ischemia-Reperfusion and GLP-1
Receptor Agonism. D.J. Sassoon, A.G. Goodwill, J.N. Noblet,
A.M. Conteh, B.P. Herring, J. McClintick, J.D. Tune, K.J.
Mather. Indiana Univ. Sch. of Med.
B587 770.2
Myostatin Inhibition as an Adjuvant Therapy in
Type 1 Diabetes Mellitus. T.J. Hawke, S. Coleman, I. Rebalka,
D. D’Souza, N. Deodhare. McMaster Univ., Canada.
B588 770.3
The Role of Ankrd2 in Obesity-Induced
Inflammation and Insulin Resistance. A.M. HernandezCarretero, N. Weber, N.Y.T. Doan, O. Osborn. UCSD and
Pomona Col., CA.
B589 770.4
Improved Insulin-Mediated Glucose Oxidation
in Cultured Human Myotubes following Roux-en-Y Gastric
Bypass Surgery. K. Zou, J.M. Hinkley, S. Park, D. Zheng, G.L.
Dohm, J.A. Houmard. East Carolina Univ.
B590 770.5
Higher Cell Growth/Viability Accompanied
by Reduced Myosin Heavy Chain Expression in Skeletal
Muscle Cells Derived from Severely Obese Type 2 Diabetic
Humans. K.D. Turner, K. Zou, M. Hinkley, S. Park, D. Zheng,
J. Houmard. East Carolina Univ.
769. HEAT SHOCK PROTEINS AND
MUSCLE FUNCTION
771. GENOMICS OF OBESITY, DIABETES,
CARDIOVASCULAR, KIDNEY AND BEYOND
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
B581 769.1
Effects of Gender, Aging, and Training Mode
on Muscular Heat Shock Protein and Contractile Adaptations
in Mice. K. Huey, T. Drake, G. Dillon, A. Wilhelmi. Drake Univ.
B582 769.2
HSP72 Is Required for Exercise-Induced
Protection against Ventilator-Induced Diaphragm Dysfunction.
A.J. Smuder, A.B. Morton, S.E. Hall, B. Ahn, M.P. Wiggs,
N.R. Wawrzyniak, S.K. Powers. Univ. of Florida.
B591 771.1
Phosphorylation of α-Actinin-4 at Serine
159 Mimics the Biochemical and Cellular Effects of Human
Kidney Disease Mutations. D. Feng, R. Krishnan, L. Stella, M.
Schenone, C.R. Hartigan, M.R. Pollak. Beth Israel Deaconess
Med. Ctr. and Havard Med. Sch., Univ. of Rome Tor Vergata
and Broad Inst. of Harvard and MIT.
B592 771.2
Histone
Deacetylase
Inhibitors
Exhibit
Enhanced Kidney Functions in Guanylyl Cyclase-A/Natriuretic
Peptide Receptor-A Gene-Disrupted Mice: Role of Epigenetic
Mechanisms. P. Kumar, R. Periyasamy, U. Subramanian,
K.N. Pandey. Tulane Univ. Hlth. Sci. Ctr.
245
S
U
N
PHYSIOLOGYSUNDAY
B593 771.3
RNA Next Gen Sequencing of Kidneys from
Diabetic Rats Provides Insights into Reno-protective Effects
of Vitamin D Receptor Activation. S.S. Prabhakar, K. Kam, R.
Kottapalli, C. Yego. Texas Tech Univ. Hlth. Sci. Ctr.
B594 771.4
Transcriptomic Profiling in Cardiovascular
Disease with Renal Failure in Human. D. Lee, J. Xu, E. Zhang,
L. Ho, T. Kong, T. Lu. Brigham and Women’s Hosp., Harvrad
Med. Sch., Harvard Univ. and MIT.
B595 771.5
RNA-Seq Analysis of Paired Servo-controlled
Kidneys Suggests Molecular Pathways Affected by Pressure.
A. Dayton, L.C. Evans, C.Yang, P. Liu, K.W. Ahn, J.D. Bukowy,
F. Stingo, M. Vannucci, P. Laud, M. Liang, A.W. Cowley; Jr.
Med. Col. of Wisconsin, Univ. of Texas MD Anderson Cancer
Ctr. and Rice Univ.
B596 771.6
Whole Genome and RNA Sequencing Identifies
Genetic Factors Involved in Nephron Deficiency in the HSRA
Congenital Solitary Kidney Rat. X. Wang, A.C. Johnson, M.R.
Garrett. Univ. of Mississippi Med. Ctr.
B597 771.7
Independent and Pleiotropic Gene Effects on
Hypertension and Metabolic Syndrome in Lyon Hypertensive
Rats. A.E. Kwitek, J.M. Pettus, J.A. Jakoubek, M.C.J. Ma.
Univ. of Iowa.
B598 771.8
Searching for the Genetic Basis of Impaired
Placentation in the Dahl Salt Sensitive Rat Model of
Superimposed Preeclampsia. J.M. Sasser, A.C. Johnson,
M.R. Garrett. Univ of Mississippi Med. Ctr.
B599 771.9
Exercise Training in the Metabolic Syndrome
Improves Perivascular Adipose Gene Expression. E.
DeVallance, K. Branyan, K. Lemaster, R. Skinner, S.
Brooks, W. Sheets, R. Bryner, J. Frisbee, P. Chantler. West
Virginia Univ.
B600 771.10 RNAseq Analysis of Exercise, Heat, and
Dehydration Stress in a Kona Ironman World Championship.
E.C-H. Lee, S. Aizik, F. Haddad, F.P. Zaldivar, D.J. Casa, L.E.
Armstrong, R.L. Stearns, C.X. Munoz, J.M. Bartley, C.M.
Maresh. Univ. of Connecticut, Univ. of California Irvine Hlth.
and The Ohio State Univ.
B601 771.11 Epigenetic
Regulation
of
Macrophage
Polarization and Renal Inflammation. S. Pushpakumar, L.
Ren, R. Biswas, U. Sen. Univ. of Louisville.
B602 771.12 The Circadian Clock Protein Per1 and
Aldosterone Mediate Opposing Action on Endothelin-1
Expression in Murine Collecting Duct Cells. M. Michel, K.
Solocinski, B.D. Cain, C.S. Wingo, M.L. Gumz. Florida
Intl. Univ., Univ. of Florida and NF/SG Veterans Hlth. Syst.,
Gainesville, FL.
B603 771.13 Integrating GWAS and Experimental Data to
Predict Targets and Models for Mechanistic Validation of Genetic
Determinants of Salt-Sensitive Hypertension. M. Hultström,
M.W. McBride. Uppsala Univ. and Univ. of Glasgow.
B604 771.14 A Novel Mechanism of Pressure Natriuresis
as Revealed in Global, Kidney-Selective and Conditional
Proximal Tubule-Specific NHE3 Knockout Mice. X.C. Li, M.
Soleimani, J.L. Zhuo. Univ. of Mississippi Med. Ctr. and Univ.
of Cincinnati.
B605 771.15 Contribution of Innate and Adaptive Exercise
Capacity as Determinants of Health and Longevity in Rats.
L.G. Koch, S.L. Britton, N.R. Qi. Univ. of Michigan.
246
772. CONTROL OF BREATHING: CHEMORECEPTION
Poster
Exhibit Halls A-D
B606 772.1
New Theory of Holistic Integrative Physiology
and Medicine II: Mechanism of Breathing Control. X-G. Sun.
Fuwai Hosp., Chinese Acad. of Med. Sci., Beijing.
B607 772.2
Activation of Bitter Taste Receptors in Rat
Pulmonary Sensory Neurons Augments Capsaicin-Evoked
TRPV1 Responses. Q. Gu, D. Joe, C. Gilbert, S. Gabriel.
Mercer Univ. Sch. of Med.
B608 772.3
Role of BK in Hypoxia-Induced Elevation of
[Ca2+]i in Depolarized Rat Carotid Body Glomus Cells. J. Wang,
J.O. Hogan, D. Kim. Chicago Med. Sch., Rosalind Franklin
Univ. of Med. and Sci.
B609 772.4
Cystic Fibrosis Transmembrane Conductance
Regulator Is Crucial for CO2 Signal Transduction in Avian
Intrapulmonary Chemoreceptors. R.G. Molloy, T.M. Low, P.R.
Bassett, J-G. Lonjaret, S.C. Hempleman. No. Arizona Univ.
B610 772.5
Blocking Volume Regulated Anion Channels
with DCPIB Depresses Avian Intrapulmonary Chemoreceptor
Discharge More in Tonic Than Phasic Units. R.G. Molloy, P.R.
Bassett, J-G. Lonjaret, K.L. Burchinal, S.C. Hempleman.
Northern Arizona Univ.
B611 772.6
Metabolic Implications of Single-Unit Avian
Intrapulmonary Co2 Chemoreceptor Responses to Sustained
Anoxia and Normoxia. T.M. Low, S.C. Hempleman, R.G. Molloy,
I.C. Solomon. No. Arizona Univ. and SUNY Stony Brook.
B612 772.7
The Enhanced CO2 Chemoreflex Is Associated
with Increased Number of CO2-Activated Orexin Neurons in the
Lateral Hypothalamus in Spontaneously Hypertensive Rats. A.
Li, E. Nattie, S. Roy. Dartmouth Geisel Sch. of Med.
B613 772.8
Orexin 1 Receptors Are Necessary for
Phase-Specific Enhancement of the Hypercapnic Ventilatory
Response in Female Rats Subjected to Neonatal Stress. L.T.
Lopes, R. Gulemetova, G. Drolet, F. Bretzner, R. Kinkead.
Laval Univ. and CHUL, Quebec City.
B614 772.9
Chronic Exposure to Elevated Ambient CO2
Influences the Orexinergic System in the Lateral Hypothalamus
and Dorsocaudal Medulla. J.W. Sherwood, R.S. Beard, C.S.
Landon, J.B. Dean. Univ. of South Florida.
B615 772.10 Hyperoxia and Hypercapnic Acidosis Increase
Free Radical Production and Cellular Excitability in Rat Caudal
Solitary Complex Brain Slices. G. Ciarlone, J.B. Dean. Univ. of
South Florida.
B616 772.11 Administering CO2 Anesthesia to Male
Sprague-Dawley Rats Prior to Euthanasia for Postmortem
Brain Slicing Alters Cardiorespiration In Vivo and O2-/CO2Sensitive Redox Signaling in Dorsocaudal Medullary Neurons
in Brain Slices. G.E. Ciarlone, C.S. Landon, J.B. Dean. Univ.
of South Florida.
B617 772.12 There Is a Greater Ratio of Phox2B Positive
Neurons to Total Neurons in the Nucleus of the Solitary Tract
Than in the Dorsal Motor Nucleus of the Vagus. M. Smith, P.F.
Martino, J. Miller, S. Neumueller, M.R. Hodges, H.V. Forster.
Carthage Col. and Med. Col. of Wisconsin.
SUNDAYPHYSIOLOGY
B618 772.13 Conditional Knockout of Astrocytic Kir4.1
Channels Impairs Central Respiratory Drive Despite
Maintaining a Subset of Cx26+ Astrocytes within the RTN. V.E.
Hawkins, F.W. Kolling IV, C.E. Nelson, D.K. Mulkey. Univ.
of Connecticut.
B619 772.14 The Inwardly-Rectifying Potassium Channel
Subunit Kir5.1 Contributes to Acute and Chronic pH
Homeostasis in Rats. M.R. Hodges, M.M. Puissant, A.M.
Geurts. Med. Col. of Wisconsin.
B620 772.15 The Hypercapnic Ventilatory Response and
Behavior in Ca2+-Activated K+ (BK) Channel Knockout Mice.
R.W. Putnam, L.G.A. Patrone, C.A. Ratliff, L.H. Gargaglioni.
Wright State Univ. and São Paulo State Univ.
B621 772.16 How Inhibition of CO2/H+-Sensitive Ionic
Currents Affects the Firing Rate of a Single-Neuron Model of
Central Chemoreceptors? M.C. Quintero, J.M. Cordovez, R.
Putnam. Univ. de Los Andes, Colombia and Wright State Univ.
B622 772.17 Influence of CO2 and HCO3- on Basal Activity
and Acid Sensitivity of Chemosensitive Neurons in the
Retrotrapezoid Nucleus. C.M. Goncalves, F-S. Kuo, E. Daniel,
D.K. Mulkey. Univ. of Connecticut.
B623 772.18 Noradrenergic Modulation of Chemosensitive
Neurons in the Retrotrapezoid Nucleus. F-S. Kuo, B.F. Barna,
D. Chen, A.C. Takakura, D.K. Mulkey. Univ. of Connecticut
and Univ. of São Paulo.
B624 772.19 Effects of 5-HT2A and 5-HT7 Receptors in the
RTN Region on Breathing during Eupnea and Hypercapnia. C.
Muere, M. Hodges. Med. Col. of Wisconsin.
773. CONTROL OF BREATHING: DEVELOPMENT
Poster
Exhibit Halls A-D
B625 773.1
Restoration of Brain Serotonin Synthesis
in Tph2 Knockout (Tph2-/-) Rats Significantly Increases
Eupneic Ventilation during Postnatal Development. B. Massat,
P. Martino, M. Hodges. Carthage Col., WI and Med. Col.
of Wisconsin.
B626 773.2
Role of Central Serotonin in Sleep Architecture
and Arousal in Infant Rat Pups. J. Young, M. Hodges, K.
Cummings. Univ. of Missouri-Columbia and Med. Col.
of Wisconsin.
B627 773.3
Role of Central Serotonin in Sleep Architecture
and the Control of Breathing during Sleep in Adult Rats.
J. Magnusson, A. Li, M. Hodges, K. Cummings. Univ. of
Missouri-Columbia, Geisel Sch. of Med. at Dartmouth and
Med. Col. of Wisconsin.
B628 773.4
Characteristics in the Vulnerability of the
Respiratory Neural Control System during a Critical Window of
Postnatal Development. P.M. MacFarlane, C.A. Mayer. Case
Western Reserve Univ., Rainbow Babies & Children’s Hosp.
B629 773.5
Caffeine Improves Survival in AutoresuscitationImpaired Serotonin-Deficient Rats. S. Lee, E. Nattie. Geisel
Sch. of Med. at Dartmouth.
B630 773.6
Developmental Changes in Trigeminal
Motoneuron Properties in the American Bullfrog, Lithobates
catesbeianus R. Kinkead, S. Fournier, S. Chamberland. Univ.
Laval, Québec.
B631 773.7
Maturational Changes in Phenotype and
Electrophysiological Properties of Bötzinger Complex Postinspiratory Neurons of Rats. D.J.A. Moraes, M.P. da Silva,
W.A. Varanda, B.H. Machado. Sch. of Med. of Ribeirão Preto,
Univ. of São Paulo.
B632 773.8
and Medicine IV: Fetus Is Not Breathing and How We Start It
after Birth. X-G. Sun. Cardiovasc. Fuwai Hosp., Chinese Acad.
of Med. Sci., Beijing.
B633 773.9
Thyroid
Hormone
Deficiency
Disrupts
Respiratory Control Development and Responses to
Hypoxia in Newborn Rat. J-P. Rousseau, R. Kinkead. Univ.
Laval, Québec.
774. LUNG PHYSIOLOGY:
PULMONARY HYPERTENSION
Poster
Exhibit Halls A-D
B634 774.1
Roles of Protein Kinase D in Vasoconstriction
and Hemodynamics. Y. Sugawara, Y. Mizuno, H. Kawakami, T.
Goto. Yokohama City Univ., Japan.
B635 774.2
Pressurized Pulmonary Arteries from the
TWIK-2 Knockout Mouse Exhibit Increased Vascular Reactivity.
M.G. Kitagawa, D.J. Durgan, J. Reynolds, R.M. Bryan; Jr.,
L.M. Pandit. Baylor Col. of Med., Texas Childrens Hosp. and
Michael E. DeBakey VA Med. Ctr., Houston.
B636 774.3
Calcineurin -NFAT Signaling Molecules
Regulate Proliferation, Migration and Apoptosis in PASMCs of
Pulmonary Hypertensive Rats Induced by Monocrotaline. M-J.
Lin, R-L. He, X-R. Liu, L-X. Gui, R-X. Wang, Y-P. Mu, J.S.K.
Sham. Fujian Med. Univ., China and Johns Hopkins Univ. Sch.
of Med.
B637 774.4
HDAC6-Hsp90 Interplay in Pulmonary Arterial
Hypertension. S. Chabot, O. Boucherat, G. Ruffenach, S.
Breuils-Bonnet, E. Tremblay, S. Provencher, S. Bonnet.
Laval Univ.,Québec.
B638 774.5
JNK2 Regulates Vascular Remodeling in
Pulmonary Hypertension. M. Das, W.M. Zawada, J. West, K.
Stenmark. Univ. of Colorado Denver, Aurora and Vanderbilt
Univ. Med. Ctr.
B639 774.6
Acute Hypoxia and Ryanodine Receptor
Activity in Pulmonary Arterial Myocytes of High Altitude
Acclimatized Fetal and Adult Sheep. G. Goyenaga, T. Yoo, M.
Romero, J. Puglisi, L.D. Longo, S.M. Wilson. Loma Linda
Univ. Sch. of Med. and California North State Univ. Sch. of Med.
B640 774.7
Chronic and Acute Hypoxia Markedly Alter
Ca2+ Signaling in Adult and Fetal Pulmonary Arterial Myocytes.
K. Cothran, S. Sandy, M. Romero, A. Dobyns, R. Paez, M.
Francis, M.S. Taylor, L.D. Longo, C.G. Wilson, S.M. Wilson.
Loma Linda Univ. Sch. of Med., California Baptist Univ. and
Univ. of South Alabama Col. of Med.
B641 774.8
Sympathetic Nerve Activity and Baroreflex
Dysfunction Paralleled the Progression of Pulmonary Arterial
Hypertension in Monocrotaline-Induced Rat Model. M.
Shinoda, Y. Oga, K. Saku, K. Abe, T. Tohyama, Y. Kuwabara,
K. Yoshida, T. Takehara, K. Fujii, A. Nishizaki, T. Kishi, T.
Ide, K. Sunagawa. Kyushu Univ. Grad. Sch. of Med. Sci. and
Kyushu Univ. Hosp., Japan.
247
S
U
N
PHYSIOLOGYSUNDAY
B642 774.9
Pulmonary Arteries Show Differences in
the Effects of Angiotensin II Stimulation of Mitochondrial
Superoxide on Regulation of Heme Biosynthesis and Soluble
Guanylate Cyclase Expression. D. Patel, M.R. Kelly, J.J.O.
Accarino, D. Sun, M.S. Wolin. New York Med. Col.
B643 774.10 Hot, Heat and Stretch All Contribute to the
Enhanced Ca2+ Signaling in Pulmonary Arterial Hypertension.
S. Song, A. Yamamura, H. Yamamura, A. Babicheva, H. Tang,
R.J. Ayon, K.M. McDermott, X. Sun, S.M. Black, A. Makino,
J.X-J. Yuan. Univ. of Arizona, Nagoya City Univ. and Kinjo
Gakuin Univ., Japan.
B644 774.11 Calcium-Sensing Receptor, Coupled with
Transient Receptor Potential Canonical Channels 6, Regulates
Cytosolic [Ca2+] in the Development and Progression of
Pulmonary Hypertension. H. Tang, A. Yamamura, D.R.
Fraidenburg, S. Song, H. Yamamura, J. Chen, Y. Gu, R.J.
Ayon, S.M. Black, J.G.N. Garcia, A. Makino, J.X-J. Yuan.
Univ. of Arizona, Kinjo Gakuin Univ., Japan, Univ. of Illinois
at Chicago and Grad. Sch. of Pharmaceut. Sci., Nagoya City
Univ., Japan.
B645 774.12 Macrophages Are Part of Cause, Not
Consequence, in PAH. M. Talati, S. Gladson, T. Blackwell, S.
Shay, R. Hamid, J. West. Vanderbilt Univ. Med. Ctr.
B646 774.13 Hypoxia Reduces HUWE1 by Downregulating
PPAR&γ in Mouse Lungs and Human Pulmonary Artery
Endothelial Cells. B-Y. Kang, J.M. Kleinhenz, T.C. Murphy,
R.L. Sutliff, C.M. Hart. Emory Univ. Sch. of Med. and Atlanta
VA Med. Ctr.
B647 774.14 Hypoxia Decreases Trx2 Protein and Activity
in Pulmonary Vascular Cells. B.E. Wade, S.E. Adesina, C.M.
Hart, R.L. Sutliff. Emory Univ./Atlanta VA Med. Ctr.
B649 774.16 Chronic Hypoxia Elevates Basal Tone in
Neonatal Pulmonary Hypertension through PKCβ and Reactive
Oxygen Species Signaling. J.R. Sheak, N.L. Jernigan, B.R.
Walker, T.C. Resta. Univ. of New Mexico.
B650 774.17 Hypoxic Pulmonary Hypertension Is Not
Affected by Neonatally Induced Diabetes in Rats. K. Chalupsky,
O. Vajnerova, T. Kratzerova, J. Durisova, D. Mikova, P.
Rachacova, R. Sedlacek, J. Herget, V. Hampl. Inst. of Molec.
Genet., ASCR, Prague and Charles Univ., Czech Republic.
B651 774.18 Canonical Transient Receptor Potential 4
Protein Encodes High Frequency Calcium Transients in
Severe Pulmonary Arterial Hypertension. C.M. Francis, N. Xu,
C. Zhou, T. Stevens. Univ. of South Alabama.
B652 774.19 The Geometry of the Progression of
Occlusive Lesions in Severe Pulmonary Arterial Hypertension.
C.M. Francis, K. Oshima, T. Stevens, M. Oka. Univ. of
South Alabama.
B653 774.20 Reduced Membrane Cholesterol following
Chronic Hypoxia Limits Depolarization-Induced Ca2+ Entry in
Pulmonary Arterial Endothelial Cells. B. Zhang, J. Naik, N.
Jernigan, T. Resta, B. Walker. Univ. of New Mexico.
B654 774.21 Ventilatory and Cerebrovascular Responses to
Hypercapnia in Pulmonary Arterial Hypertension. S. Malenfant,
P. Brassard, M. Paquette, O. Le Blanc, A. Chouinard, S.
Bonnet, S. Provencher. Quebec Heart and Lung Inst.
B655 774.22 G Protein-Coupled Receptor Expression
in Pulmonary Artery Smooth Muscle Cells of Human and
Experimental Models of Pulmonary Arterial Hypertension. N.
Aroonsakool, K. Sriram, A.V. Michkov, P.A. Insel. UCSD.
248
B656 774.23 eNOS Methylation at R494 Is Increased with
Hypoxia Exposure and May Be Associated with Decreased NO
Production. L.G. Chicoine, R. Rafikov, S. Black, L.D. Nelin,
A.J. Cardounel. The Ohio State Univ. Wexner Med. Ctr.,
Nationwide Children’s Hosp., Univ. of Arizona Col. of Med. and
Univ. of Pittsburgh Med. Ctr.
B657 774.24 Metabolic Syndrome and Heart Failure with
Preserved Ejection Fraction: A New Model of Pulmonary
Hypertension Associated with Left Heart Disease. F. Potus,
B. Ranchoux, E. Tremblay, S. Provencher, S. Bonnet. Univ.
Laval, Canada.
B658 774.25 Aquaporin 1 Elevates cMyc and Cyclin D1 via
β-Catenin in Pulmonary Arterial Smooth Muscle Cells. X. Yun,
H. Jiang, N. Lai, L. Shimoda. Johns Hopkins Univ.
775. LUNG PHYSIOLOGY: VASCULAR SMOOTH
MUSCLE CELL BIOLOGY, VASCULAR
REGULATION, AND HYPOXIA
Poster
Exhibit Halls A-D
B659 775.1
Acid Sensing Ion Channel 1 Contributes to
Hypoxia-Induced Proliferation and Hypertrophy in Mouse
Pulmonary Arterial Smooth Muscle Cells. T.R. Yellowhair, L.M.
Herbert, T.C. Resta, N.L. Jernigan. Univ. of New Mexico.
B660 775.2
Ubiquitin Proteasome System in Pulmonary
Hypertension. B.E. Wade, C.M. Hart, R.L. Sutliff. Emory Univ.
and Atlanta VA, Decatur.
B661 775.3
BK Channel Differences in Near-Term Fetal
and Adult Ovine Small Pulmonary Arteries. D.A. Hessinger,
G.U. Thorington, I. Sokolova, W.H. Fletcher, M.R. Pretorius,
D.P. Morris, L.D. Longo. Loma Linda Univ.
B662 775.4
Extracellular Adenosine Diphosphate Ribose
Mobilizes Intracellular Ca2+ via Purinergic-Dependent Ca2+
Pathway in Rat Pulmonary Artery Smooth Muscle Cells. C.
Huang, J. Hu, K.P. Subedi, A.H.Y. Lin, J.S.K. Sham. Johns
Hopkins Univ. Sch. of Med., Fujian Med. Univ. Guangzhou
Chest Hosp., China.
B663 775.5
Sex Differences in Sepsis-Induced Nitric Oxide
and EDHF Signaling Pathways in Rat Pulmonary Artery. G.
Kuntamallappanavar, M.D. Leo, J. Subramani, S. Mishra.
Univ. of Tennessee Hlth. Sci. Ctr., Memphis, Texas Tech Inst.
and Indian Vet. Res. Inst., Bareilly.
MONDAY, APRIL 4
Across Societies
776. TEACHING, LEARNING AND TESTING IN THE
BIOLOGICAL AND BIOMEDICAL SCIENCES II
Poster
Mon. 9:00 am—San Diego Convention Center,
Exhibit Halls A-D
Education
Sunday through Tuesday. Presentation time is for Monday only.
T38
776.1
Enabling a Viable Pipeline of NHLBI Extramural
Investigators in Fiscally Challenging Times. C. Maric-Bilkan,
M. Charette, Y. Oh, P. Schum, Y. Gao, C. McDonald, D. Reid,
V. Robinson, D. Stanley, K. Fuentes, M. Olive, M. Eblen, K.
Pearson, E. Tolunay, Z. Galis. NHLBI, NIH.
T39
776.2
Effectiveness and Reception of Clinical
Pathophysiology Lectures for Physician Assistant Students.
F.K. Johnson, M.P. Seaman. LMU-DeBusk Col. of Osteo.
Med., TN.
T40
776.3
The Prevalence of Exercise PrescriptionRelated Course Offerings in U.S. Pharmacy School Curricula:
Exercise Is Medicine® A.J. Dirks-Naylor, C.L. Griffiths, J.L.
Gibson, J.A. Luu. Wingate Univ.
T41
776.4
A Sustainable Medical Anatomy Program
Supported with Small 3-D Printed Human Parts. S. Perez.
Univ. of Arizona Col. of Med. Phoenix.
T42
776.5
In Final Examinations, Quality of Essay Plan
Correlates with the Essay Mark. P. Langton. Sch. of Physiol.,
Pharmacol. and Neurosci., Univ. of Bristol, U.K.
T43
776.6
Promoting Motivationally and Educationally
Productive Behaviors with Collaborative Testing. R.N.
Cortright, H. Lujan, L.A. Johnson, S.E. DiCarlo. East
Carolina Univ. and Wayne State Univ.
T44
776.7
Collaborative Testing Improves Performance
on Long Answer Questions, and Maintains Long-Term
Retention of Course Material. K.L. Ritchie, R. Rajakaruna, G.
Newton. Univ. of Guelph, Canada.
T45
776.8
Students as the Unit and Instrument of Analysis
for the Assessment of Advising. K.M.S. Johnson, K. Greene,
E. Guttchen, R. McLeod, Z.W. Paquin, M.K.M. Young. Beloit
Col., WI.
T46
776.9
Use of Remote Assessment Using an Online
Learning Management System: Evaluation by Outcomes
Assessment. J. Kingsbury. Arizona State Univ. Col. of Letters
and Scis.
T47
776.10 Tactical post hoc Exam Key Review. J.A. Price
III. Oklahoma State Univ. Ctr. for Hlth. Scis.
T48
776.11 Effect of Educational Games on Knowledge
Acquisition in Physiology. F.K. Marcondes, K.C. Gavião, L.T.
Cardozo, A.B.A. Moraes. FOP - UNICAMP, Piracicaba, Brazil.
T49
776.12 An Active Learning Activity Utilizing a Headline
News Story to Engage Students, Enhance Interest, and
Improve In-Class Learning of Cell Cycle Regulation. A.J.
Dirks-Naylor. Wingate Univ.
T50
776.13 Effects of In-Class Discussion with Pre- and
Post-Lecture Quizzing on Retention. C.E. Akers, K. Flann.
Univ. of Portland.
T51
776.14 “Fact-Ways”: Teaching Cellular Signaling Using
the Nobel Archives. E.P. Seidlitz, S. Nastos, P.K. Rangachari.
T52
776.15 The Testing Effect Varies with Spaced versus
Massed Learning of Skeletal Muscle Information. J. Dobson,
J. Perez. Georgia Southern Univ.
T53
776.16 Open Educational Resources in the Laboratory:
Moving the Introductory Biology Laboratory Manual onto
Pressbooks. S. Knight, M. Bentley, L. Regner, L. Murphy.
American Univ.
T54
776.17 Benefits of the Students Who Grade Pathology
Assignments of Their Near-Peers. S.K. Biswas, A. Basu, J.
Ram. St Matthews Univ. Sch. of Med., Grand Cayman.
T55
776.18 Do “Job Aids” Facilitate Retention of Physiology
Concepts. M. Povlow, D. Harris. Univ. of Central Florida Col. of
Med. and Med. Educ., Orlando.
T56
776.19 Benefits of Online Textbook Resources Depend
on Physiology Students Using Retrieval. L.C. Anderson, S.A.
Keirstead. Univ. of Minnesota, Minneapolis.
T57
776.20 Developing Online Guided Self-Assessments
in Cardiovascular Physiology for Medical School. T.A. Pressley,
J.C. Fowler. Texas Tech Univ. Hlth. Sci. Ctr.
T58
776.21 How Do We Train Our Future Faculty to
Teach? Results from a Multidisciplinary Comparison of
Pedagogy Courses Offered at a Large Midwestern University.
V.D. O’Loughlin, K.D. Kearns, J.M. Robinson, C. SherwoodLaughlin. Indiana Univ. Sch. of Med., Indiana Univ. and Indiana
Univ. Sch. of Publ. Hlth.
T59
776.22 Problem-Based Learning Is a More Effective
Method at Developing Critical Reasoning Skills When
Compared to Traditional Instructional Methods. B.M. Franklin,
L.M. Xiang, J.M. Paulose, J.A. Collett, M.K. Rhoads, J.L.
Osborn. Univ. of Kentucky and Indiana Univ. Sch. of Med.
T60
776.23 Using Longitudinal Fabricated Patient Panels
to Integrate Clinical and Basic Science Education in a Spiraled
Preclinical Medical Curriculum. D.L. Osborne, S.J. Howell, D.E.
Bramblett, N. Minugh-Purvis, C.M. Galin, R.H. Selinfreund,
H. Vilchis, R.J. Ketchum, D.W. Rodenbaugh. Burrell Col. of
Osteo. Med., NM.
T61
776.24 “Absolut
Polycythemia”:
Non-traditional
Case-Based Instruction in Physiology Related to Alcohol
Consumption. M.B. Harris. Univ. of Alaska Fairbanks.
T62
776.25 The “420” Ptosis: Non-traditional CaseBased Instruction in Physiology Related to Endocannabinoid
Influences on the Sympathetic Nervous System and Cannabis
Consumption. M.B. Harris. Univ. of Alaska Fairbanks.
T63
776.26 Student Feedback from Independent Study
Modules on Prerequisite Review and Areas of Misconception
in Physiology. R.E. Laudadio, T.E. Wilson. Marion Univ. Col. of
Osteo. Med., IN.
249
M
O
N
ACROSS SOCIETIES/ANATOMY
MONDAY
T64
776.27 Pros and Cons of Active Learning. T.R.
Chakraborty. Adelphi Univ.
T65
776.28 Usefulness and Student Preferences for
Interactive Pre-lecture Modules as Part of Flipped Instruction
in Biomechanics. Z.J. Domire, P.M. Rider. East Carolina Univ.
T66
776.29 Integration of Digital/Blended Pedagogy and a
Data Acquisition System to Enhance Anatomy and Physiology
Laboratory Teaching for Allied Health Students: A LearnerCentric Strategy. K. Dutta. Univ. of New England.
T67
776.30 Innovative Methods Common in Non-science
Disciplines Equally Effective in Physiology Courses. M.K.
Hopper. Indiana Univ. Sch. of Med., Evansville.
T68
776.31 Blended Learning within an Undergraduate
Exercise Physiology Laboratory. S.J. Elmer, K. Carter, A.J.
Armga, J.R. Carter. Michigan Technol. Univ.
T69
776.32 Use of Flipped Classroom Teaching Approach
on Student Performance in Physiology. C. Gopalan. So. Illinois
Univ. Edwardsville.
T70
776.33 The
Formation
of
Student
Learning
Communities in a Life Science First-Year Course. L. Parks, J.
Lubischer. North Carolina State Univ.
T71
776.34 Effects of a Team-Based Learning Environment
on Student Outcomes in Anatomy and Physiology for First Year
Pharmacy Students. H.M. Jones. Lake Erie Col. of Osteo. Med.
T72
776.35 Student Perceptions and Effectiveness of
Team-Based Learning in an Undergraduate Anatomy and
Physiology Course. S. Luckey, N. McLaughlin. Seattle Univ.
T73
776.36 Assessment of Team Cohesiveness, Potency
and Reflexivity with First-Year Medical Small Group Activities.
M.W. Lee, C. Gabelica, S.M. Fiore. Univ. of Texas at Austin
Dell Med. Sch., Glasgow Caledonian Univ., U.K. and Univ. of
Central Florida.
777. COMPUTERS IN RESEARCH AND TEACHING
Poster
Exhibit Halls A-D
Education
Sunday through Tuesday. Presentation time is for Monday only.
T1
777.1
Adding a Checklist to the Medical
Neuroscience Laboratory Guide When Using a ComputerAssisted Neuroanatomical Learning Tool. A.R. Severson.
Univ. of Minnesota, Duluth.
Anatomy
778. BIOLOGICAL ANTHROPOLOGY
Poster
Exhibit Halls A-D
Evolution/Anthropology
A281 778.1
Measurement Theory and the P-Matrix:
Ramifications of Variable Choice. K.R.R. Savell, B.M.
Auerbach. Univ. of Tennessee, Knoxville.
A282 778.2
Differences in Trace Elements over 10
Thousand Years: Comparison of Superficial Enamel Pb, Mn,
Zn, Cu, Sr, Cd, Ba, and Ag. J. Ramos, A.S. Bilal, T.C.I. Toledo,
M.A.M.S. Veiga, T.A. Maranhao, J.C. Ramos, S.R.P. Line, C.
Cartelle, R.F. Gerlach. Univ. of São Paulo, Fed. Univ. of Santa
Catarina, Sch. of Dent. of Piracicaba, UNICAMP and Pontifical
Catholic Univ. of Minas Gerais, Brazil.
A283 778.3
Manganese in Human Teeth. M. JelacaTavakoli, R.F. Gerlach, M. Djuric. Southwestern Col., CA,
Dent. Sch. of Ribeirão Preto, Univ. of São Paulo and Univ. of
Belgrade, Serbia.
A284 778.4
Preliminary Analysis of Skeletal Trauma from
an Atypical Early Colonial Period Pit Burial with Comparison to
Fractures Observed among Typical Late Intermediate Period
(ca AD 1250) Above-Ground Tombs in the Ancash Region of
Highland Peru. A. Titelbaum, B. Ibarra. Univ. of Arizona Col.
of Med.-Phoenix and Tulane Univ.
A285 778.5
Metric Variation in the Human Sacrum: Costal
Process Length among Black and White South Africans. C.R.
Wayne. LSU, Baton Rouge.
250
A286 778.6
Morphological Integration and Changes
in Pelvic Dimensions with Age in Adult Female Humans.
A.M. Mallard, K.R.R. Savell, B.M. Auerbach. Univ. of
A287 778.7
Primate Diversity of the Nasal Conchae: Are
There Functional Differences? N.H. Kimura, A.S. Pagano, W.
Lawson, S. Márquez. SUNY Downstate Col. of Med., NYU
Sch. of Med. and Icahn Sch. of Med. at Mount Sinai.
A288 778.8
Assessing Differences in the Functional
Morphologic Relationships of the Nasal Cavities of Anatomically
Modern Humans, Neanderthals, and Mid-Pleistocene Homo
A.S. Pagano, J.T. Laitman, S. Marquez. NYU Sch. of Med.,
Icahn Sch. of Med. and SUNY Downstate Col. of Med.
A289 778.9
Cranial
Base
Angulation:
Examining
Congruence of Interior and Exterior Measurements.
E.R. Agosto, S.J. Williams, B.M. Auerbach. Univ. of
A290 778.10 Complications in 3D Quantitative Analysis of
Sexual Dimorphism of the Human Nuchal Area. L.T. Gaona,
D.F. Royer. Univ. of Colorado Denver, Anschutz Med. Campus.
A291 778.11 Effects of Geography, Genetics, and
Environment on Morphological Variation in Two Subspecies of
Common Chimpanzee. M.L. Burgess, J-A. Junno, C.B. Ruff.
Johns Hopkins Univ. Sch. of Med. and Univ. of Oulu, Finland.
A292 778.12 Exploring Ecogeography, Drift, and Selection
on the Macaque Cranium. S.J. Williams, B.M. Auerbach.
Univ. of Tennessee, Knoxville.
A293 778.13 The Effects on Subtalar Neutral Angle in
Non-weight Bearing Position on Postural Stability. Q.F. Gan,
N. Dalayi, C. Simon, E. Chinnavan, S.R. Rajagopal Naidu.
AIMST Univ., Malaysia.
MONDAYANATOMY
A294 778.14 Contrasting Force Reduction at the Greater
Trochanter Using Different Surgical Procedures for Relief of
Greater Trochanteric Pain Syndrome. V. Taylor II, A. Wood, R.
Belmares, G. Guttmann, R. Reeves. Wake Forest Med. Ctr.
and Univ. of North Texas Hlth. Sci. Ctr.
A295 778.15 Body Mass Estimation from the Knee: Forensic
Applications. N. Squyres, C. Ruff. Johns Hopkins Univ.
779. FORM, FUNCTION AND MORPHOLOGY
Poster
Exhibit Halls A-D
Developmental Biology/Morphology
A296 779.1
Comparative Anatomy of the Ischiorectal
Fossa and Pudendal Canal in Humans and Domestic Animals.
J.R. Rodriguez-Sosa, M. Hall, B. Adrian, J.H. Plochocki.
Midwestern Univ., AZ.
A297 779.2
Polyisomerism, Anisomerism, and the Evolution
and Development of the Vertebrate Head Muscles. J.M.
Ziermann, R. Diogo. Howard Univ. Col. of Med.
A298 779.3
Insight Into the Anatomy of the Poor Visual
System in the Adult African Giant Rat( Cricetomys gambianus
Waterhouse) J.N. Alawa, S. Amuzor, S.J. Sambo, C.B. Alawa.
Bingham Univ., Kara, Nigeria, Ahmadu Bello Univ. and Univ. of
Abuja, Nigeria.
A299 779.4
Scaling of the Ectotympanic Tube and Tympanic
Membrane Diameter among Catarrhine Primates. E.E.I.
Fricano, V.B. DeLeon. Johns Hopkins Univ. and Univ. of Florida.
A300 779.5
Gape and Fiber Architecture of the Chewing
Muscles in Primates and Phalangeroid Marsupials. J.M.G.
Perry, E.E.I. Fricano, T.M. Harper. Johns Hopkins Univ.
A301 779.6
Using Novel Methods to Visualize Jaw Muscle
Biomechanics and Its Significance for the Evolution of the Avian
Feeding Apparatus. A.T. Spates, I.N. Cost, K.C. Sellers, K.M.
Middleton, C. Holliday. Univ. of Missouri-Columbia.
A302 779.7
Dental Wear, Molar Shape and Dietary
Adaptation in Early Australopithecus N.M. Bauer, E.R.
Middleton, C.V. Ward. Univ. of Missouri-Columbia.
A303 779.8
Ontogeny of Enamel Thickness in the Teeth of
Alligator and Its Significance for Crocodyliform Dental Evolution.
A.B. Schmiegelow, K.C. Sellers, C.M. Holliday. Univ.
A304 779.9
Cervical Vertebral Morphology and Neck
Mobility in Gibbons (Hylobates lar) and Humans. N. GriderPotter, R. Goto, Y. Nakano. Sch. of Human Evol. and Soc.
Change, Arizona State Univ. and Osaka Univ.
A305 779.10 Hippopotamus
(Hippopotamus
amphibius
and Choeropsis liberiensis) Shoulder Osteology and Function
Compared with Suids (Sus scrofa, Phacochoerus aethiopicus,
Potmochoerus porcus and Hylochoerus meinertzhageni) and
Tayasuids (Tayassu peccary and Tayassu tajacu) V.L. Naples.
Northern Illinois Univ.
A306 779.11 Is Olecranon Length Reflective of Adaptations
for Speed or Power in Anthropoids? M.S. Selby. Georgia
Campus, Philadelphia Col. of Osteo. Med.
A307 779.12 Development of Wing Bone Laminarity in
the Pigeon. R.M. Ourfalian, K. Ezell, A.H. Lee. Midwestern
Univ., AZ.
A308 779.13 Human Soft Tissue Pelvic Anatomy: Evolutionary
and Clinical Perspectives. J.H. Plochocki, J. Rodriguez-Sosa,
M.I. Hall. Midwestern Univ., AZ.
A309 779.14 Effects of Selection for High Voluntary Wheel
Running on Sexual Dimorphism in the Sacrum of Mus musculus
C.L. Asplund, K.W. Perry, H. Schutz. Pacific Lutheran Univ.
A310 779.15 Trabecular Bone Mass and Daily Travel Distance
in Mammals. H. Chirchir, C.B. Ruff, K.M. Helgen, R. Potts.
Marshall Univ., Natl. Museum of Natural Hist., Washington, DC,
Johns Hopkins Univ. Sch. of Med. and Natl. Museums of Kenya.
A311 779.16 Variability in the Post-hatching Growth
Trajectory of Alligators from Eggs Incubated with and without
the Eggshell. E. Gonzalez, J. Doyle, M. Noriega, A. Hocson,
N.A. Membreno, R.M. Elsey, T. Owerkowicz. California State
Univ., San Bernardino and Rockefeller Wildlife Refuge, Grand
Chenier, LA.
A312 779.17 Optimization of Technical Photographic
Variables to Assess Newborn Length Using Photographic
Imaging. M.N. Orozco, R. Gwaltney, N.W. Solomons.
CeSSIAM, Guatemala City and Tufts Univ., Boston.
A313 779.18 Ontogenetic Cranial and Postcranial Regional
Variation in Bone Strength: Comparisons in Two Archaeological
Populations. E.M. Garofalo, M.A. Holmes. Univ. of Arizona Col.
of Med. and Sch. of Med., Duke Univ. (231.2)
A314 779.19 Structural and Sensorimotor Deficits Associated
with Abnormal Frontal Plane Motion of the Knee during Gait: The
Multicenter Osteoarthritis Study. A.E. Wink, J. Niu, D.T. Felson,
M.C. Nevitt, J. Torner, C.E. Lewis, C.A. Brown, N. Shakoor, L.
Sharma, K.D. Gross. Boston Univ. Sch. of Med., UCSF, Univ.
of Iowa, Univ. of Alabama at Birmingham Sch. of Med., Rush
Univ. Med. Ctr., Northwestern Univ. Feinberg Sch. of Med. and
Massachusetts Gen, Hosp. Inst. of Hlth. Professions, Boston.
A315 779.20 Variations in the Branching of the Lingual and
Facial Arteries. M.E. Hurley, W.Y. Lee, H. Beyea, T. Stevens, J.
Den haese, M.P. Olivieri. D’Youville Col., NY.
M
O
N
780.IMAGING
Poster
Exhibit Halls A-D
A316 780.1
Differential Lectin Binding and Coronary
Angiography in a Danio and Non-model Fish Species. W. He, T.
Manalo, A. May, J. Quinn, P.J. Lafontant. DePauw Univ.
A317 780.2
The Application of Iodine-Enhanced MicroCT Scanning Protocols to Analyze Multiple Tissue Types and
Organ Systems in Mouse Embryos with Short-Term Gestational
Hypoxia. R.E. Fisher, G. Chapman, S.L. Dunwoodie, K.
Kusumi. Univ. of Arizona Col. of Med. Phoenix, Arizona State
Univ. and Victor Chang Cardiac Res. Inst., Sydney.
A318 780.3
Basis Microscopy: Label-Free Imaging of the
Native, Living Cellular Nano-architecture. L.M. Almassalha, G.
Bauer, J. Chandler, S. Gladstein, L. Cherkezyan, Y. StypulaCyrus, S. Weinberg, D. Zhang, P. Thusgaard Ruhoff, H.
Roy, H. Subramanian, N. Chandel, I. Szleifer, V. Backman.
Northwestern Univ., Northwestern Feinberg Sch. of Med., Univ.
of So. Denmark and Boston Univ.
251
ANATOMYMONDAY
A319 780.4
Surgery to Relieve Thoracic Outlet Syndrome
Complaints Should Have Preoperative Imaging: MRI/MRA/MRV.
J.D. Collins, E.H. Saxton, H.A. Gelabert, A. Carnes. UCLA and
UCSF, Fresno.
A320 780.5
Assessment of Myocardial Architecture
Depends on Imaging DTMRI Parameters. P. Agger, C. Laustsen,
V. Hjortdal, M. Pedersen. Aarhus Univ. Hosp., Denmark.
A321 780.6
Using CT Scans to Assess Early Postnatal
Development of the Bony Eustachian Tube and Hyolaryngeal
Apparatus: A Test of Reliability. J. Meaike, A. Gupta, A. Pagano,
D.F. Curcio, P. Som, J.T. Laitman. Icahn Sch. of Med. at Mount
Sinai, NYU Sch. of Med. and Santa Casa Sch. of Med. Sci.,
São Paulo.
A322 780.7
Use of Axial CT Scans to Assess Early Postnatal
Development of the Internal Nares: A Test of Reliability. A. Gupta,
J. Meaike, A. Pagano, D.F. Curcio, P. Som, J.T. Laitman. Icahn
Sch. of Med. at Mount Sinai, NYU Sch. of Med. and Santa Casa
Sch. of Med. Sci., São Paulo.
A323 780.8
Pole-Shark (Galeorhinus galeus): Seriated CTScanned Cross-Sections Every 1mm of the Rostral Extremity
and Reconstructions. P.P. Le Floch-Prigent, S. Verdeille.
Versailles-Saint Quentin Univ. and CIMOP, Saint-Cloud, France.
781. ANATOMY EDUCATION: FIXATION
TECHNIQUES/PRESERVATION MODALITIES
Poster
Exhibit Halls A-D
A324 781.1
Development of a Multidisciplinary Clinical
Cadaver Program. R.E. Sandeski, G. Kovacs. Dalhousie
Univ., Canada.
A325 781.2
The Heart of Fascia: Initial Steps toward a
Three Dimensional Model of the Human Extracellular Matrix
in Dissection Lab. L. Nemetz. Pace Univ. and Anatomy
Trains, ME.
A326 781.3
Successful Soft Cure Embalming of a Whole
Body Cadaver after Three Years in a Cryogenic State. S.
Heltzel, M. Sochor, D. Sikon, R. Sikon. Univ. of Virginia and
Virginia State Anat. Prog.
782. ANATOMY EDUCATION: DISSECTION VERSUS
ALTERNATIVE METHODS
Poster
Exhibit Halls A-D
A327 782.1
A Comparison Study of Model-Based Anatomy
Learning and Cadaver-Based Learning. S. Chowdhury, U.
Akter. St. Louis Community Col.-Wildwood and St. Louis
Community Col.-FV, Saint Louis.
252
A328 782.2
Musculoskeletal
Anatomy
Education:
Evaluating the Influence of Different Methods of Delivery on
Medical Students Perception and Academic Performance. J.
Peeler, A. Longo, H. Bergen. Univ. of Manitoba.
A329 782.3
A Comparison of Student Approach to Learning
between Dissection- and Prosection-Based Undergraduate
Human Anatomy Courses. S.C. McWatt, G.S. Newton, L.C.
Jadeski. Univ. of Guelph, Canada.
A330 782.4
A Kinetic Model for Learning Gross Anatomy.
E.R. Malone, M. Pine, G. Bingham. Texas A&M Univ.
A331 782.5
Prosection-Based Gross Anatomy Lab for
Dental Students. L.E. Sanders, G. Dorius, D.A. Morton, D.A.
Hutcheson. Univ. of Utah.
A332 782.6
Educational Outcomes of Implementing
Prosected Hands and Feet as Educational Tools in a
Traditionally Full Dissection Medical Gross Anatomy Laboratory.
S.R. Williams, A. Sinning, A. Notebaert, R. Darling. Univ. of
Mississippi Med. Ctr.
A333 782.7
Are Prosections an Effective Supplemental
Tool for Improving Students’ Knowledge of Neck Anatomy?
S. Alshehry, J. Sedlmayr, J. Cork. LSU Hlth. Sci. Ctr.,
New Orleans.
A334 782.8
Do Screen Display Systems Improve Anatomy
Student Performance? M.A. Bardales-Cahua, D.R. UlloaDeza, L.J. Fernández-Rodríguez. Antenor Orrego Private
Univ., Peru.
A335 782.9
Pilot Study: Integration of 3-D Dissection Table
into Undergraduate Gross Anatomy Course. C.O. Lane; Jr.
Prairie View A&M Univ.
A336 782.10 A Refined Study of the Effect of Cadaver
Dissection on Written and Practical Gross Anatomy Test
Scores. M.P. Olivieri, M.I. Hurley, M.E. Gervasi, N.R. Olivieri,
E.M. Rokitka, L. Georger, G. Bistulfi. D’Youville Col., NY and
Univ. at Buffalo Sch. of Dent. Med., SUNY.
783. ANATOMY EDUCATION: LABORATORY
TEACHING STRATEGIES
Poster
Exhibit Halls A-D
A337 783.1
Clinical Anatomy and Imaging Lab: Vertical
Integration in a Preclinical Cardiovascular Course. M. Hankin,
E. Downs, D. Barry, N. Malik, J. Moak, V. Soukoulis, J. Dent.
Univ. of Virginia Sch. of Med.
A338 783.2
Cadaver Biopsies and CT Scans Spur an
Investigative and Analytic Approach to Dissection. D.L. Davies,
C.M. Quick, S.F. Malak. Univ. of Arkansas for Med. Sci.
A339 783.3
The Use of a Checklist to Increase the Quality
of Student Dissections in Medical Gross Anatomy Labs. E.
Johnson, J. Foster. Alabama Col. of Osteo. Med.
A340 783.4
The Use of “Structured Lab Review” to
Augment Student Learning and Its Impact on Cadaveric
Practical Examination Performance. C. Vasan, M. Gentile, N.
Vasan. Cooper Med. Sch. of Rowan Univ.
A341 783.5
Assessing Formative Feedback after Table
Conferences in the Icahn School of Medicine’s Structures
Course. P. Maffucci, B. Laitman, J. Laitman. Icahn Sch. of
Med. at Mount Sinai.
MONDAYANATOMY
A342 783.6
A
Comparison
of
Approaches
and
Comprehensive Guide for a Complete Cadaveric Central
Nervous System Extraction. R. Hlavac, K. Nelson, M.E.
Stabio. Univ. of Colorado Anschutz Med. Campus.
COMPARATIVE APPROACHES
Poster
Exhibit Halls A-D
A343 784.1
The Anatomy of Healthcare Student
Perceptions. J.L. Dowdy, C.M. Martin, C.A. Nichols, A.C.
Edmondson. Med. Col. of Georgia at Augusta Univ. and Univ.
of Western Ontario.
A344 784.2
The Utility of Cadaver-Based Approaches for
the Teaching of Human Anatomy: A Survey of British and Irish
Anatomy Teachers. J.Y. Balta, M. Cronin, J.F. Cryan, S.M.
O’Mahony. University Col. Cork, Ireland.
A345 784.3
How the Distinctive Cultures of Osteopathic and
Allopathic Medical Schools Affect the Careers, Perceptions, and
Institutional Efforts of Their Anatomy Faculties: A Qualitative
Case Study of Two Schools. J. Byram, C. Traser, T. Arbor, J.
Brokaw. Indiana Univ. Sch. of Med. and Marian Univ. Col. of
Osteo. Med., Indianapolis.
785. ANATOMY EDUCATION: TEACHING AND
LEARNING STRATEGIES/METHODS
Poster
Exhibit Halls A-D
A346 785.1
Applications of the Anatomy Comics. M.S.
Chung, B.S. Chung. Ajou Univ. Sch. of Med., South Korea.
A347 785.2
A Short Mindfulness Activity to Reduce Anxiety
State of Dissection and Prosection Students Prior to Their First
Cadaver-Based Laboratory Experience. W. Albabish, J. Bigg,
G.S. Newton, L. Jadeski. Univ. of Guelph, Canada.
A348 785.3
Experiencing Embodied Learning: A MixedMethods Analysis of a Yoga Anatomy Workshop. B. Klein, M.
Sugrue, M. Loyet. Indiana Univ. and Midwestern Univ., IL.
A349 785.4
Seeing Is Knowing: Instructor Perceptions
of Teaching an Online Undergraduate Anatomy Course with
Laboratory. S.M. Attardi, N.M. Mintz, J. Barnett, K.A. Rogers.
Western Univ., Canada and Oakland Univ. William Beaumont
Sch. of Med., WI.
A350 785.5
Anatomists as Coaches for Developing Clinical
Professionals. L.J. Rizzolo. Yale Univ.
A351 785.6
Instructor Presence and the Value of
Instructor-Student Interface in the Gross Anatomy Laboratory.
N. Contreras, C.J. Harper, N. Lachman, F.W. Hafferty,
W. Pawlina. Mayo Med. Sch. and Mayo Clin. Col. of Med.,
Mayo Clin.
A352 785.7
Applied Anatomy Labs: Interactive Small
Group Learning. A.L. Mork, B. Klement, D.F. Paulsen, L.E.
Wineski. Morehouse Sch. of Med.
A353 785.8
Integration of Active-Learning Activity Increased
Short-Term and Long-Term Retention in a Self-Learning
Setting. L.B. Ruest, K.K.H. Svoboda, L.A. Opperman. Texas
A&M Univ. Baylor Col. of Dent.
A354 785.9
Enhancing Active Learning in a Medical Gross
Anatomy and Embryology Course: A Flipped Classroom
Approach. K.M. Harrell. East Carolina Univ. Brody Sch. of Med.
A355 785.10 The Flipped Anatomy Classroom: Does It Help
Reduce Study Time Outside the Classroom? G.T. Dorius,
Y. Zhang, L.M. Olson, J. Colbert-Getz, D.A. Morton. Univ.
of Utah.
A356 785.11 How to Support Student Motivation in a
Flipped Anatomy Course: Introducing the “mflip” W. Saltarelli,
K. Robinson, E. Bovee, P. Beymer, L. Linnenbrick-Garcia, C.
Roseth. Central Michigan Univ. and Michigan State Univ.
A357 785.12 Student Learning and Retention in Introductory
Anatomy Flipped Class Models Compared to Traditional
Lecture Format. M.J. McCullough, M.G. McCullough. Adrian
Col. and Onsted Community Schs., MI.
A358 785.13 Comparison of Mono-Lecture and DualLecture Modes in the First Year Medical Education. J. Chen,
W.P. Daley, G. Yang, D. Cui. Univ. of Mississippi Med. Ctr.
A359 785.14 A Blended Learning Approach for Human
Skeletal Anatomy with Undergraduate Students. T.R.
Wakeham, B.E. Morin, J.J. Durocher. Michigan Technol. Univ.
A360 785.15 Counting the Dead: Who Is Teaching Anatomy
to Physical Therapy Students? J.M. Cope, M. Precht, A.
Klinepeter, B. Powell. Elon Univ.
A361 785.16 Can a Cranial Nerve Animation Enhance
Dental Student Learning? Employing an Innovative Teaching
Aid in the Classroom. M. Lone, J.P. McKenna, J.F. Cryan, T.
Vagg, A. Toulouse, E.J. Downer. Cork Univ. Dent. Sch. and
Hosp., University Col. Cork and Trinity Col. Dublin.
A362 785.17 Evaluating the Impact of the Supplemental
Instruction Program on Student Academic Performance in
Gross Anatomy at the Medical College of Georgia at Augusta
University. Y.E. Peng, A.L. Rossi, A.C. Edmondson. Med.
Col. of Georgia at Augusta Univ.
A363 785.18 Anatomical Education, Memory Consolidation
and the Testing Effect. R.A. Easteal, J. Biddell. Queen’s
Univ., Canada.
A364 785.19 QTD Effects on Veterinary Anatomy Learning.
D. Ahn, J. Sim.
Col. of Vet. Med., Chonbuk Natl. Univ. and Col. of Med. Sci.,
Jeonju Univ., South Korea.
A365 785.20 Evaluation of Power Point Presentation
Reflection among Students of Applied Medical Sciences
College, Najran University. A.E. Mokhtar, S.D. Elmustafa.
Najran Univ., Saudi Arabia.
253
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ANATOMYMONDAY
786. ANATOMY EDUCATION: CURRICULUM DESIGN
AND EFFECTIVENESS
Poster
Exhibit Halls A-D
A366 786.1
A Remediation Strategy for Gross Anatomy in
the New Horizons Curriculum. M.A. Pizzimenti. Univ. of Iowa.
A367 786.2
A Comparison of Three Neuroscience
Curriculum Models in an Osteopathic Medical School. S.M.S.
Hassan, C. Thomann, S. Bhatia, R. Theobald. A. T. Still
Univ., MO.
A368 786.3
Teachers Perception on the Integration of
Morphological Sciences Discipline in Integrated Clinical
Curriculum in Santa Casa De São Paulo School of Medical
Sciences. M.D. Barros, V.A. Silva, A.C.C. Pinto, C.S.B.
Pereira, B.M. Liquidato. Santa Casa Sch. of Med. Sci.,
São Paulo.
A369 786.4
Effectiveness of a Course Utilizing CadaverBased Dissection in Preparation for Gross Anatomy as
Perceived by Undergraduate Students upon Entry to
Professional School. J. Dennis, A. Barry. Missouri So.
State Univ.
A370 786.5
What to Teach or Not to Teach, That Is the
Question: Anatomy Objectives in a Modern Medical Curriculum.
N. Metti, F. Anwar, V. Lyons, M. Bee. Univ. of Detroit Mercy
and Geisel Sch. of Med., Dartmouth Univ.
787. ANATOMY EDUCATION: CLINICAL SKILLS
Poster
Exhibit Halls A-D
A371 787.1
Using Ultrasound to Assess Accuracy of Liver
Measurement and Palpation during Early Medical Training.
G.L. Brower, V. Tipton, J. Kim, V.H. Lee, F.R. Prabhu. Texas
Tech Univ. Hlth. Sci. Ctr.
A372 787.2
Utilization of the Point of Care Ultrasound
Training in Patients Management by Medical Residents: A
Place in the Anatomy Curriculum R. Jirjis, I. Hajj Hussein, A.
Jurjus, K. Zakaria. Oakland Univ. William Beaumont Sch. of
Med., American Univ. of Beirut and Wayne State Univ.
A373 787.3
Preliminary Multi-site Usage for the Online
‘Medical Imaging Solution for Teaching and Research’ Y.
Carter, J. Costa, B. Burbridge. Univ. of Massachusetts Med.
Sch. and Univ. of Saskatchewan Col. of Med.
A374 787.4
Assessing Simulation-Based Interventional
Angiography Training in Novices. O. Zaika, M. Boulton, R.
Eagleson, S. de Ribaupierre. Western Univ., Canada.
A375 787.5
How to Use Anatomical Dissections and
Prossections to Contribute in Avoiding Erros in Clinical
Practice. M.D. Barros, C.L. Mendes. Santa Casa Sch. of Med.
Sci., Brazil.
254
A376 787.6
A Case-Based Learning Module on Acute
Ischemic Stroke Using Donated Medical Records. T.C. Browne,
D. Royer. Univ. of Colorado Anschutz Med. Campus.
A377 787.7
Utility of 3 Dimensional Printing of Hearts
with Complex Congenital Heart Disease in the Education of
Pediatric Trainees and Sonographers. D. Prasad, R. Ashwath.
Rainbow Babies and Children’s Hosp., Cleveland.
A378 787.8
Creation of a Learning Module for Healthcare
Graduate Students on ALS. J.R. Diouf, M.A. Pascoe, S.P.
Ringel. Univ. of Colorado Anschutz Med. Campus.
A379 787.9
Integrating Clinical Medicine with the Basic
Sciences: Pulmonology Learning Modules for Medical
Students. M. Doroudi, B. Hoomayon, R. Cohen. Univ. of
British Columbia.
A380 787.10 Correlating Clinical Reasoning Skills to Expert
Interaction in First Year Medical Students. M. Manuel, G. Rae.
LSU Hlth. Sci. Ctr., New Orleans.
A381 787.11 To What Extent Are First-Year Medical
Students Willing to Disclose Errors: Relating a Reflective
Writing Exercise in Gross Anatomy to Medical Error Disclosure.
P.Y-w. Sun, C.M. Wittich, N. Lachman, W. Pawlina. Mayo Clin.
Col. of Med.
788. ANATOMY EDUCATION: OUTREACH
Poster
Exhibit Halls A-D
A382 788.1
The Anatomy Training Program: A Participant’s
Perspective. M. Umorin. Texas A&M Univ. Baylor Col. of Dent.
A383 788.2
The Human Body and Modern Harms –
Itinerant Anatomy Museum. T.S. Masuko, R.V. Coutinho, J.O.
Gonçalves, P.S. Carvalho, Í.M. Vilasbôas, A.B. Oliveira,
M.M. Maron e Silva, J.N. Nascimento, D.F.B. Matos, L.D.A.
Santos, L.M.C. Moraes. Fed. Univ. of Bahia, Brazil.
A384 788.3
Gross Anatomy for Teacher Education:
Equipping the Anatomy Educator. W. Brooks, A. Doss. Univ.
of Alabama at Birmingham and Univ. of Alabama Sch. of Med.
A385 788.4
Individualized Learning in Anatomy to Diversify
Tomorrow’s Medical Field. J.J. Gong, B. Schindel, C. Jerome,
K.L. Antoine, A.S. Pagano, S. Márquez. SUNY Downstate
Med. Ctr. and NYU Sch. of Med.
A386 788.5
Student Demographics of Samuel Merritt
University Community Service Honor Society Volunteers. M.A.
Allen, L.B.A. Peck, C.A. Elliott, B. Puder. Samuel Merritt Univ.
MONDAYBIOCHEMISTRY
789. DNA REPAIR MECHANISMS
792. CONTROL OF DNA RECOMBINATION
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C1
789.1
Identifying the MAP Kinase Slt2/Mpk1 as a
New Interacting Protein for Mm. s2 G. Kung, Y. Wang. Saint
Louis Univ.
C2
789.2
Phenotypic and Genetic Characterization
of the Escherichia coli Protein YbjN in Response to Ionizing
Radiation. M. Menhart, S.T. Bruckbauer, M.M. Cox. Univ.
C3
789.3
Determination of Escherichia coli Genes
Involved in Resistance to DNA Alkylating Agents. S. Bellou, M.
Muenter, M. Travers, B. Leifer, S. Baig, C. Kramer, M. Qi, C.
Joshi, A. Carlson, C. Conway, P. Beuning. Northeastern Univ.
C4
789.4
Functional Significance of Meiotic Proteins in
the DNA Repair System of Bdelloid Rotifers. L.E. Dickinson,
J.C. McReynolds, A.M. Schurko. Hendrix Col., AR.
790. DNA REPLICATION MECHANISMS
Poster
Exhibit Halls A-D
C5
790.1
Coordination of Gene Expression and Cell
Cycle Progression in Response to Stress; a Novel Checkpoint
in S Phase. F. Posas Garriga, A. Duch, B. Canal, E. de Nadal.
Univ. Pompeu Fabra, Barcelona.
C6
790.2
Regulation of the Kinetoplast Maxicircle DNA
Replication by RNase HIIC in Trypanosoma brucei S. Misra,
M.K. Mittal, U.K. Singha, M. Chaudhuri, G. Chaudhuri.
Meharry Med. Col. and Vanderbilt Univ.
791. BASE EXCISION REPAIR
Poster
Exhibit Halls A-D
C7
791.1
Acetylation of DNA Polymerase Beta Regulates
the Choice of the Base Excision Repair Pathway. O.K. Howald,
L. Balakrishnan. Indiana Univ.-Purdue Univ. Indianapolis.
C8
791.2
Base Excision Repair of Bulky DNA Adducts
Generated by the Antitumor Drug Yatakemycin. E.A. Mullins,
R. Shi, Y. Igarashi, B.F. Eichman. Vanderbilt Univ. and Toyama
Prefect. Univ.
C9
791.3
Small Molecule Ogg1 Activators Ameliorate
mtDNA Oxidation and Promote Cell Health. S.R. Katchur,
A.M. Davis, E. Ellis, B. Pickard, S. Pyne, W. Rumsey.
GlaxoSmithKline and Univ. of Strathclyde, U.K.
C10 792.1
Characterizing a New Role of Novel uup Gene
in E. coli during DNA Repair. B. Joung, S.H. Chen, M.M. Cox.
Univ. of Wisconsin-Madison.
C11
792.2
Proteomic Analysis of a Meiotic Recombination
Hotspot. A.J. Storey, R.U. Protacio, A.J. Tackett, M.K.
Davidson, W.P. Wahls. Univ. of Arkansas for Med. Sci.
793. DNA REPLICATION, REPAIR
AND RECOMBINATION
Poster
Exhibit Halls A-D
C12 793.1
Breaking the Fourth Wall: Quaternary
Organizations Forge a Link to the Novel Non-enzymatic
Function of RNR-α Y. Aye. Cornell Univ. and Weill Cornell
Med., Ithaca.
C13 793.2
Tripartite DNA Lesion Recognition and
Verification by XPC, TFIIH, and XPA in Nucleotide Excision
Repair. F.M. Golebiowski, C-L. Li, Y. Onishi, N.L. Samara, K.
Sugasawa, W. Yang. NIDDK, NIH, Inst. of Molec. Biol., Acad.
Sinica, Taipei and Kobe Univ., Japan.
C14 793.3
Acetylation of Replication Protein A Improves
Its DNA Binding Property. S. Surendran, O.E. Ononye, L.
Balakrishnan. Indiana Univ.-Purdue Univ. Indianapolis.
C15 793.4
Early Replication Stress Leads to Abnormal
Mitosis and Genome Rearrangement. S. Forsburg. Univ. of
So. California.
C16 793.5
Instability within the Coding Sequence of the
Repetitive RNA Polymerase II C-Terminal Domain. A.E. Exner,
S.M. Fuchs. Tufts Univ.
C17 793.6
How DNA-Damage Machinery Protects the
Genomes of Mouse Oocytes. V.S. Rinaldi, E. Bolcun-Filas,
J. Schimenti. Cornell Univ. and The Jackson Lab., Bar
Harbor, ME.
794. MECHANISM OF DNA RECOMBINATION
Poster
Exhibit Halls A-D
C18 794.1
Defining the Cut Site Specificity of Ref – a
RecA-Dependent Endonuclease. Y-C.S. Wan, E.A. Ronayne,
M.M. Cox. Univ. of Wisconsin-Madison.
255
M
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BIOCHEMISTRYMONDAY
795. MISMATCH REPAIR
Poster
Exhibit Halls A-D
C19 795.1
Investigating the Intersection between DNA
Mismatch Repair and Triplet Nucleotide Repeat Expansion. S.
Kutlu, B. Case, M. Hingorani. Wesleyan Univ., CT.
796. NON-HOMOLOGOUS END JOINING
Poster
Exhibit Halls A-D
C20 796.1
DNA Repair Proteins XLF and XRCC4 Interact
with Telomeric Proteins TRFf1 and RA. P1 E.A. Castle, P.
Zaibaq, Q-K. Pham, Y. Aviles, J. Hou, K.T. Vu, N. Fahmy, M.
Guirette, A. Ruff, R. Jain, J. Jabbur, A. Ribes-Zamora. Univ.
of St. Thomas, Houston Houston Community Col.
797. NUCLEOTIDE EXCISION REPAIR
Poster
Exhibit Halls A-D
C21 797.1
Understanding the Efficacy of Inhibitor TRDL551 on Replication Protein A Binding Affinity. J. Kaur, L.
Balakrishnan. Indiana Univ.-Purdue Univ. Indianapolis.
798. REPLICATION FORK DYNAMICS
Poster
Exhibit Halls A-D
C22 798.1
Identifying the Role of Genomic Uracil in Folate
Deficiency. J. Chon, M. Field, J. Gondokusumo, P. Stover.
Cornell Univ.
C23 798.2
Function of Cdc45 in DNA Replication and
in Response to Genotoxic Stress. A. DeBrot, C. Lancaster,
M-A. Bjornsti. Univ. of Alabama at Birmingham and St Jude
Children’s Res. Hosp.
799. SIGNALING RESPONSES TO DNA DAMAGE
Poster
Exhibit Halls A-D
C24 799.1
Estrogen Induces RAD51C Expression and
Localization to Sites of DNA Damage. M.K. Holz. Yeshiva
Univ., NY.
256
C25 799.2
A Novel Role for RPA Phosphorylation in the
Regulation of G2 Exit in the Face of Persistent DNA Damage.
T.M. Wilson, P.L. Ghospurkar, S.J. Haring. North Dakota
State Univ.
800. SINGLE-STRAND ANNEALING
Poster
Exhibit Halls A-D
C26 800.1
Elucidation of Saw1 and Rad1-Rad10
Recruitment to Induced Single-Stand Annealing Sites as a
Function of 3′ Flap Length. J. Camberos Felix, F. Fregoso,
R. Odango, B. Iannolo, P. Fischhaber. California State
Univ. Northridge.
801. SITE-SPECIFIC DNA RECOMBINATION
AND TRANSPOSITION
Poster
Exhibit Halls A-D
C27 801.1
Interactomic and Enzymatic Analyses of
Distinct Affinity Isolated Human Retrotransposon Intermediates.
J. LaCava, K.R. Molloy, D. Fenyö, M.S. Taylor, B.T. Chait, J.D.
Boeke, M.P. Rout. The Rockefeller Univ.,NYU Sch. of Med.
and Massachusetts Gen. Hosp.
802. CHROMATIN ORGANIZATION AND
GENE REGULATION
Poster
Exhibit Halls A-D
C28 802.1
Enhancer H3K4 Methyltransferase MLL4
Controls Cell Fate Transition. K. Ge. NIDDK, NIH.
C29 802.2
The
Chromatin
Remodeling
Complex
SWI/SNF Is a Master Regulator of Meiotic Splicing in
Saccharomyces cerevisiae S. Venkataramanan, S. Douglass,
A.R. Galivanche, T. Johnson. UCLA.
C30 802.3
Identification and Characterization of GammaSynuclein as a PCBP1-Interacting Protein in Various Cancer
Cell Lines. J. Ko, A. Hunkele, H. Sultan, F. Ikalina, A. Liu, P.
Nahar-Gohad. Seton Hall Unv.
C31 802.4
Neuroprotective Actions of Hydrogen Sulfide
and Sulfhydration in the Brain. B.D. Paul, S.H. Snyder. Johns
Hopkins Univ. Sch. of Med.
C32 802.5
BRD4 Is a Histone Acetyltransferase That
Evicts Nucleosomes from Chromatin. D.N. Ballachanda,
C. Case-Borden, A. Gegonne, C.H. Hsu, Q. Chen, D.
Meerzaman, A. Dey, K. Ozato, D. Singer. NCI, NIH, Bethesda
and Rockville and NICHD, NIH.
MONDAYBIOCHEMISTRY
C33 802.6 Transcriptional and Post-transcriptional
Regulatory Mechanisms Lead to Metabolic Adjustment in
Response to Glucose Availability. A.H. Munshi, J.M. Claggett,
T.L. Johnson. UCLA.
C34 802.7
Dissection of Gene Regulatory Networks That
Control Retinal Cell Fate Specification. S. Wang, C. Cepko.
Harvard Med. Sch.
C35 802.8
Human Growth Gene Family Chromosomal
Architecture Is Affected by Maternal Obesity, Gestational
Diabetes and Insulin Treatment. Y. Jin, H. Vakili, S.
Menticoglou, P.A. Cattini. Univ. of Manitoba.
C36 802.9
Regulation of Hepatic Mouse Major Urinary
Protein Genes by the Zinc Finger and Hemeoboxes 2 and
Alpha-Fetoprotein Regulator 2 J. Jiang, K.T. Creasy, M.L.
Peterson, B. Spear. Univ. of Kentucky.
C37 802.10 Epigenetics
Impacts
Copy
Number
Heterogeneity and Drug Resistant Gene Selection. J.R.
Whetstine, J.C. Black, S. Mishra, B. Sexton, C. Van
Rechem, S. Murphy. MGH Cancer Ctr. and Harvard Med.
Sch., Charlestown.
803.TRANSCRIPTIONAL
Poster
Exhibit Halls A-D
C38 803.1
Regulatory Characteristics of Vibrio vulnificus
gbpA Encoding a Mucin-Binding Protein Essential for
Pathogenesis. S.H. Choi, K.K. Jang. Seoul Natl. Univ.
C39 803.2
Activation of p21 following DNA Damage
Transcriptionally Controlled by a Telomeric Shelterin
Protein TRF2 in a Telomere-Length Dependent Fashion.
S. Chowdhury. CSIR Inst. of Genomics and Integrat. Biol.,
New Delhi.
C40 803.3
O-GlcNAc Transferase and O-GlcNAcase
Interact with Mi2β at the Aγ-Globin Promoter. Z. Zhang, F.C.
Costa, E.P. Tan, N. Bushue, C.E. Costello, M.E. McComb,
S.A. Whelan, K.R. Peterson, C. Slawson. Univ. of Kansas
Med. Ctr. and Boston Univ. Sch. of Med.
C41 803.4
The Dynamics of TAL Effector – DNA
Interaction Reveals Optimal Number of Targeted Nucleotides
for Maximum Binding Specificity. F.C. Rinaldi, K.E. Wilkins,
A.J. Bogdanove. Cornell Univ.
C42 803.5
Defining a Transcriptional Regulatory Network
for Peroxisome Biogenesis. E.A. Paz, T. Gaasterland, A. La
Spada. UCSD.
C43 803.6
Analysis
of
Nuclease
HypersensitiveEquivalent Sites in SV40 by Next Generation Sequencing. B.
Milavetz, L. Balakrishnan, B. Woods, K. Christensen. Univ.
of North Dakota and Indiana Univ.-Purdue Univ. Indianapolis.
C44 803.7
Transgenic MyoD Is Associated with
Upregulation of Id2 mRNA during Induction of Differentiation at
Low Cell Density in Balb 10(1)- and 10T1/2-Derived Myogenic
Cells. M. Masihi, C. Aguirre, K. Tiger, P. Russel, C.J. Ibarra,
L. Lugo, L. Lumpkin, S.B. Sharp. California State Univ.,
Los Angeles.
C45 803.8
Mechanistic Study of ERCC6/CSB Enzymatic
Regulation, and Its Roles in Transcription Elongation, and
Chromatin Remodeling. D. Wang. UCSD.
C46 803.9
Chromatin Remodeler EP400 Deposits H3.3
Into Promoters and Enhancers during Gene Activation. S.K.
Pradhan, T. Su, L. Yen, K. Jacquet, J. Cote, S. Kurdistani, M.
Carey. UCLA and Laval Univ. Cancer Res. Ctr., Quebec.
C47 803.10 Distinct Kinetic Phases Associated with
Specific Transcription Factors Differentially Regulate IL1B and
TNF Genes. S.H. Pulugulla, J. Adamik, A.N. Grillini, D.L.
Galson, P.E. Auron. Duquesne Univ. and Univ. of Pittsburgh.
C48 803.11 Altered DNA-Binding Specificity Transcription
Activator Variant Provides Key to Unlocking Gene Activation
Mechanism. A.N. Meyer, P.A. Weil. Vanderbilt Univ. Med. Ctr.
C49 803.12 Her2 Breast Cancer Cells Form SuperEnhancers Which Indicate a New Mechanism of Aggression. F.
Rahmatpanah, Z. Jia, Y. Hu, B. Men, R. Jahan, M. McClelland,
D. Mercola. Univ. of California, Irvine.
C50 803.13 Electrostatic and Hydrophobic Interactions
Mediate Single-Stranded DNA Recognition and Acta2
Repression by Purine-Rich Element Binding Protein B. L.
Ferris, A. Rumora, T. Wheeler, R. Kelm. Univ. of Vermont.
C51 803.14 Structural
Basis
for
Histone
H2B
Deubiquitination by the SAGA DUB Module. M.T. Morgan,
M. Haj-Yahya, A.E. Ringel, P. Bandi, A. Brik, C. Wolberger.
Johns Hopkins Med. Inst., Ben Gurion Univ. of the Negev and
Technion-Israel Inst. of Technol.
C52 803.15 Hematopoietic Cell Stress Response Gene
Transcriptional Regulation by TFII-I and E2F Family. M. Aryan.
Univ. of Florida, Fort Myers.
804. NON-CODING RNAS
Poster
Exhibit Halls A-D
C53 804.1
Microarray Expression Profile Analysis of Long
Non-coding RNAs in Pulmonary Tuberculosis with Traditional
Chinese Medicine. T. Jiang, L-Y. Shi, L-L. Wei, Z-L. Chen,
C. Wang, C-M. Liu, Z-J. Li, J-C. Li. Zhejiang Univ., Zhejiang
Hosp., Hangzhou and The Sixth Hosp. of Shaoxing, China.
C54 804.2
Long Non-coding RNA GAS5 Suppresses
TGFβ-Smad Signaling via Intrinsic rSBE Elements. R. Tang.
Univ. of Georgia.
C55 804.3
Deletion of Five Senescence-Associated
lncRNAs in Saccharomyces cerevisiae K. Krauss, K. McMurdie,
D. Zappulla. Bellarmine Univ. and Johns Hopkins Univ.
C56 804.4
AFP Anti-sense Transcripts in Mouse Liver
and Their Potential Role in Gene Regulation. M.S. Dixon, Qiu,
B.T’. Spear, M.L. Peterson. Univ. of Kentucky.
C57 804.5
Zhx2 and the Regulation of AFP Anti-sense
RNAs in Mouse Liver. G. Qiu, M. Dixon, B. Spear, M. Peterson.
Univ. of Kentucky.
C58 804.6
Circadian Inc to EDN1-AS: A Novel, Long,
Non-coding RNA Antisense to the EDN1 Gene. K. Solocinski,
S.J. Barilovits, A.K. Welch, C.S. Wingo, B.D. Cain, M.L.
Gumz. Univ. of Florida and NF/SG Veterans Hlth. Syst.,
Gainesville, FL.
C59 804.7
Non-coding RNA Regulations in Pseudomonas
aeruginosa M.C.B. Ammons. Montana State Univ.
257
M
O
N
BIOCHEMISTRYMONDAY
805.RIBOSWITCHES
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C60 805.1
Expanding Structure Activity Relationships for
the preQ1 Riboswitch: Functional Group Requirements and
Metal Dependence in Pathogenic Aptamer Domains. M-A.
Doan, M.N. Pahl, B.K. Neilson, I.T. Suydam. Seattle Univ.
C61 805.2
Synthesis and Characterization of Ribonucleic
Acid Aptamers Targeted at aspergillus Cell Surface
Carbohydrates. M.R. Sheridan, D.R. Engelke, C.E. Rohlman.
Albion Col., MI and Univ. of Michigan.
C62 805.3
Creating a Riboswitch-Based Whole-Cell
Biosensor for Bisphenol A. M. Zorawski, J. Shaffer, E.
Velasquez, J.M. Liu. Pomona Col., CA.
806. RNA EDITING AND MODIFICATION
Poster
Exhibit Halls A-D
C63 806.1
Editing of Kv1.1 RNA Transcripts Is Altered by
Human Mutations Responsible for Episodic Ataxia Type-1 E.F.
Kiddie, K.M. Patterson, R.A. Reenan, J.J.C. Rosenthal, R.B.
Emeson. Vanderbilt Univ., Brown Univ. and Univ. of Puerto
Rico Med. Sci. Campus.
C64 806.2
Apobec-1 Complementation Factor Regulates
mRNA Stability and Polysome Distribution but Has No Role in
apoB RNA Editing. V. Blanc, J. Riordan, E. Park, S. Kennedy,
A. Mortazavi, J. Nadeau, N. Davidson. Washington Univ. Sch.
of Med., Pacific NW Diabetes Res. Inst., Seattle, UCLA and
Univ. of California, Irvine.
807. RNA MODIFICATION: MECHANISM
AND FUNCTION
Poster
Exhibit Halls A-D
C66 807.2
Post-transcriptional
Modifications
Alter
Anticodon Loop Dynamics and Codon Recognition in E. coli
tRNAArg1,2 K.L. Sarachan, W.A. Cantara, S. Vangaveti, J.L.
Spears, H. DeMirci, F.V. Murphy IV, S.V. Ranganathan, P.F.
Agris. Univ. at Albany-SUNY, Stanford PULSE Inst. and NECAT/Cornell Univ., Argonne Natl. Lab.
C67 807.3
Expanding the Roles of tRNA Thiolation in
Bacteria: Involvement of 2-Thiouridine tRNA in Signaling
Bacterial Sulfur Metabolism. K.A. Black, N.J. Kus, P.C. Dos
Santos. Wake Forest Univ.
C68 807.4
RNA Editing-Mediated Modulation of CalciumDependent Activator Protein for Secretion 1 Function. R.B.
Emeson, R.J. Ulbricht, R.M. Lazarenko, C.E. DelBove, Q.
Zhang. Vanderbilt Univ.
258
808. RNA TURNOVER
C69 808.1
Phosphorylation-Independent
Recruitment
of 14-3-3 to Tristetraprolin Partially Impairs Deadenylation
by Blocking Ccr4, but Not Pan2, Association. A.M. Nunez
Castrejon, M. Tun, R. Nava, L. Kraemer, S.L. Clement. Cal
Polytech State Univ., San Luis Obispo and Allan Hancock Col.,
Santa Maria, CA.
C70 808.2Withdrawn
C71 808.3
Determining the Effect Nutrient Availability Has
on the Activity of the 3’-5’ Exoribonuclease Rr. p6 T. Ryan, K.P.
Callahan. St. John Fisher Col., NY.
C72 808.4
Vacuolar Turnover of rRNA Mediated by an
Autophagy-Dependent Mechanism Is Necessary to Maintain
Cellular Homeostasis. G.C. MacIntosh, B. Floyd, S. Morriss,
D. Bassham. Iowa State Univ.
C73 808.5
Effects of Aging and Nitrogen Deprivation on
Nonfunctional rRNA Decay in Saccharomyces cerevisiae D.
Zekan, F.J. LaRiviere. Washington and Lee Univ.
C74 808.6
The Effect of Ultraviolet Stress on
Nonfunctional rRNA Decay. K.J. Villarroel Gomez, F.J.
LaRiviere. Washington and Lee Univ.
C75 808.7
Ascertaining a Role for Rnp1p in Posttranscriptional Gene Control in S. cerevisiae K.E. Mackay, S.P.
Segal. Winona State Univ.
C76 808.8
Dephosphorylation of the RNABinding Protein
Tristetraprolin by PP2A in LPSStimulated Macrophages. S.A.
Smolgovsky, M.E. Caldwell, B.M. Parsons, M.E. Cahill, S.L.
Clement. California Polytech State Univ., San Luis Obispo.
C77 808.9
Characterization of the Ubiquitin Binding
Properties of the Deadenylase Pa. n2 Z. Swinney, J. Teruya,
N. Vengoechea, S.L. Clement. California Polytech State Univ.,
San Luis Obispo.
809. BUILDING MOLECULAR MACHINERY
Poster
Exhibit Halls A-D
C78 809.1
Design and Development of Chemically Gated
Artificial Regulatory Domains. D.T. Cunningham-Bryant. Univ.
of Washington.
C79 809.2
Development of a Natural Protein Synthesis
System from Pseudomonas aeruginosa C. Hughes, Y.
Escamilla, Y. Hu, J.M. Bullard. Univ. of Texas Rio Grande
Valley, Edinburg.
C80 809.3
Using Synthetic Biology Methods to Construct
a Rapid and Efficient Estrogen Biosensor. M. Lynott, S.
Huttelmaier, D. Tobiason, J. Canfield. Simmons Col., MA and
Carthage Col., WI
MONDAYBIOCHEMISTRY
810.CHAPERONES
813. PROTEASES IN DISEASE
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C81 810.1
Exploring GTP Control of Bacterial Respiratory
System Specific Chaperone Interaction with Its Substrate
Protein’s Twin-Arginine Signal Peptide. S.J. Cherak, R.J.
Turner. Univ. of Alberta and Univ. of Calgary, Canada.
C82 810.2
The Production of Extracellular Vesicles Is
Increased after Heat Shock. A. De Maio, D. Hawisher, B. Lara,
D.M. Cauvi. UCSD.
811. MOLECULAR CHAPERONES: MECHANISM
AND FUNCTION
Poster
Exhibit Halls A-D
C83
811.1
Mortalin Caught in Action: Structures of the
Nucleotide Binding Domain in the Apo, ADP-Bound and
AMP+PPi-Bound States. M. Moseng, M. Mignery, P. Larney,
C. Emerson, J.C. Nix, R.C. Page. Miami Univ. and Lawrence
Berkeley Natl. Lab.
C84
811.2
Biochemical Characterization of the Interaction
between Innate Immune Receptor Nod2 and Its Chaperones.
H.C. Wastyk, V. Mohanan, A. Schaefer, C-W. Hou, M. Lauro,
C.L. Grimes. Univ. of Delaware.
C85
811.3
Differential Action of Purifying Selection
Explains the Evolution of the Major Chaperone Sub-network in
Humans. K. Hess, J. Ellis, P. Nguyen, N. Nikolaidis. California
State Univ. Fullerton.
C86
811.4
Naturally Occurring Mutations Alter the Function
of HSPA1A, a Key Regulator of the Cellular Stress Response in
Humans. R.M. Oliverio, K. Hess, N. Nikolaidis. California State
Univ., Fullerton.
C87
811.5
En’Cas’ing the Stress: Engineering a Human
Cell Line Knockout of Heat Shock Response Coordinator Genes
Using CRISPR Cas9 System. G.I-I. Canales, B. Pani, E. Nudler.
Univ. of Maryland Baltimore County and NYU Langone Med. Ctr.
C88
811.6
Functional Cooperativity between the Trigger
Factor Chaperone and the ClpXP degradation System. W.A.
Houry. Univ. of Toronto.
812. GENETIC STUDIES OF PROTEIN SYNTHESIS
Poster
Exhibit Halls A-D
C89 812.1
Evaluation of ADAMTS Levels in Patients
with Chronic and Aggressive Periodontitis. K. Demircan, A.
Tayman, N.A. Bayram, B. Tuğtağ Demir, Z. Fırat Karagöz,
T. Fıstık, Ş. Kurga, C. Önder, M. Günhan. Turgut Ozal Univ.,
Ankara Univ. and Gazi Univ., Turkey.
C90 813.1
Testing Specificity of Commercially Available
Nicastrin Antibodies. J. Hatter, D. Dries. Juniata Col., PA.
C91 813.2
A Trypsin-Like Protease from Alternaria
alternata Allergens Promotes Airway Inflammation through
Activation of Protease-Activated Receptor-2/β-Arrestin
Signaling. M.C. Yee, H.L. Nichols, K. Pal, D. Polley, K.J.
Lee, M. Ming, M.D. Seigler, M.D. Hollenberg, M.O. Daines,
S. Boitano, K.A. DeFea. Sch. of Med., Univ. of California,
Riverside, Univ. of Calgary, Canada and Univ. of Arizona.
C92 813.3
Compulsive Grooming and Hyperactivity in
Nicastrin Conditional Knockout Mice. D.R. Dries, J. Zhu,
S.G. Birnbaum, G. Yu. Juniata Col., PA and Univ. of Texas
C93 813.4
Comparison between hPEP and spPEP
Inhibition When Varying Size and Position of Inhibitory Peptide
of Casein α s1 A.K. Vishram, B.A. Clack. Stephen F.
Austin State Univ.
C94 813.5
Transcriptome Analysis
of
Conditional
Knockout Mice. C. Biefeld, K. Sztroin, Y. Zhu, G. Yu, D. Dries.
Juniata Col., PA and Univ. of Texas Southwestern Med. Ctr.
C95 813.6
Deletion of nicastrin Leads to Hypomyelination
and Transcriptional Changes in Juvenile Mice. M. Yamato,
Y. Zhu, D. Dries, G. Yu. Juniata Col., PA and Univ. of Texas
814. PROTEIN AGGREGATION AND
AMYLOID DISEASES
Poster
Exhibit Halls A-D
C96 814.1
Liquid-Liquid Phase Separation of hnRNP A2
and Implications for Structure and Disease Propagation. C.V.
Chabata, V. Ryan, N.L. Fawzi. Brown Univ.
C97 814.2
What Pathological Mutants Tell Us About
Synuclein Aggregation Pathways. A. Bhumkar, Y. Gambin,
A. Leitao, Q. Bowden, N. Giles, B. Francois, D. Hunter, T.
Boecking, E. Sierecki. Univ. of New South Wales and Inst. for
Molec. Biosci., Brisbane.
C98 814.3
Prion-Like Protein Polymerisation Underlies
Signal Transduction in Innate Immunity: The Emergence of a
Universal Mechanism? A. O’Carroll, T. Ve, D. Lau, N. Giles, M.
Moustaqil, A. Bhumkar, D. Hunter, B. Kobe, T. Boecking, E.
Sierecki, Y. Gambin. Univ. of New South Wales, Griffith Univ.
and Sch. of Chem. and Molec. Biosci., Brisbane.
C99 814.4
Discovery of a New Prion-Like Behaviour
Linked with Infantile Epilepsy. E. Sierecki, Y.J. Chai, V.M.
Tomatis, R.S. Gormal, N. Ariotti, N. Giles, D. Xia, R.G. Parton,
B. Collins, F.A. Meunier, Y. Gambin. Sch. of Med. Sci., Univ. of
New South Wales and Univ. of Queensland.
259
M
O
N
BIOCHEMISTRYMONDAY
C100 814.5
Effects of Cinnamon Extract on Glycogen
Synthase Kinase 3 Phosphorylation of Tau. J. Donley, W. Hurt,
A. Stockert. Ohio Northern Univ.
C101 814.6
Protein Disulfide Isomerase Can Reverse the
Aggregation of α-Synuclein. H. Burress, L. Cilenti, A. Serrano,
M. Taylor, S. Tatulian, K. Teter. Univ. of Central Florida.
C102 814.7
The Molecular Basis for Cross-Species Prion
Transmission. T. Kurt, L. Jiang, N. Alderson, J. Liu, D.
Eisenberg, C. Sigurdson. UCSD and UCLA.
815. PROTEIN TARGETING
Poster
Exhibit Halls A-D
C103 815.1
Effect of rLosac (Lonomia obliqua stuart-factor
activator) on Skin Wound Healing. S.A. Andrade, A.C. Sato,
M.P. Alvarez-Flores, R. Bosch, A.M. Chudzinski-Tavassi.
Butantan Inst., São Paulo.
C104 815.2
Preclinical Trials of Amblyomin-X: A Toxicity
Study in Mice. A.M. Chudzinski-Tavassi, S.E. Will, J.M.
Sciani, R. Bosch, M.B. Goldfeder, D.A. Maria. Butantan Inst.,
São Paulo.
816. PROTEIN TURNOVER AND QUALITY CONTROL
Poster
Exhibit Halls A-D
C105 816.1
Ataxin3 Deubiquitination Activity Is Stimulated
by Association with Specific Binding Partners. M.V. Rao, P.J.
Loll. Drexel Univ. Col. of Med.
C106 816.2
Expression of Herpud1 during Osteoclast
and Osteoblast Differentiation. C. Quiroga, L. Americo Da
Silva, G. Mansilla, I. Oyarzún, M. Bustamante, P. Castro, H.
Verdejo. Pontifical Catholic Univ. of Chile, Santiago.
C107 816.3
A Hect Domain Ubiquitin Ligase Mediates the
Degradation of Unassembled Nuclear Proteins in Mammalian
Cells. Y. Xu, Y. Ye. NIDDK, NIH.
C108 816.4
Structural Determinants of human Tryptophan
2,3-Dioxygenase Protein Degradation. S. Kim, S. Karkashon,
S-R. Yeh, M.A. Correia. UCSF and Albert Einstein Col. of Med.
C109 816.5
ER Protein Quality Control and Lipid Droplets:
Unexpected Functional Connections. J.A. Olzmann. Univ. of
C110 816.6
p97 Is Critical for Cardiac Proteostasis and
Dysregulation of p97 Activity Causes Cardiomyopathy. M.J.
Brody, J. Karch, J.D. Molkentin. Cinncinnati Children’s Hosp.
Med. Ctr. and HHMI.
260
817. PROTEIN TURNOVER IN CELL REGULATION
Poster
Exhibit Halls A-D
C111 817.1
N-End-Rule-Mediated Degradation of the
Proteolytically Activated Form of PKC-Theta Kinase Attenuates
Its Pro-apoptotic Function. M.A. Eldeeb, M. Esmaili, R.
Fahlman. Univ. of Alberta.
818. SYSTEMS BIOLOGY OF
CELLULAR NETWORKS
Poster
Exhibit Halls A-D
C112 818.1
Skeletal Muscle Wasting and Inflammatory
Regulation by Ovarian Function and IL-6 in Tumor Bearing
Mice. O. Reszczynski, A. Saum, K. Hetzler, J. Carson. Univ.
of South Carolina.
C113 818.2
Computational Analysis of Next Generation
Sequencing Data Predicts Potential Sources of Phenotypic
Variation in Human Glucocorticoid Signaling. S.M. Ryan, T.M.
Forst, F.G. Martz, P.J.M. Murphy. Seattle Univ.
819. SYSTEMS BIOLOGY AND PROTEOMICS
Poster
Exhibit Halls A-D
C114 819.1
Bioinformatic and Functional Analysis of
Venom from the Jewel Wasp Ampulex compressa R. Arvidson,
M. Kaiser, S. Pan, F. Libersat, M.E. Adams. Univ. of California,
Riverside and Ben Gurion Univ. of the Negev.
C115 819.2
Mechanism of Action Identified in 30 Days: A
Systems Biology Approach. A. Vertes, A.R. Korte, C. LombardBanek, P. Nemes, L. Lida Parvin, Z.J. Sahab, B. Shrestha,
S.A. Stopka, W. Yuan, D.I. Bunin, M. Knapp, I. Mason, D.M.
Nishita, A. Poggio, C.L. Talcott, M. Yadav, B.M. Davis, A.I.
Larriera, C.A. Morton, C.J. Sevinsky, M.I. Zavodszky, N.J.
Morris, H.R. Anderson, M.J. Powell, T.T. Razunguzwa.
George Washington Univ., SRI Intl., Menlo Park, GE Global
Res., Niskayuna, NY and Protea Biosci. Inc., Morgantown, WV.
C116 819.3
Dynamic Organellar Maps, a Tool to Study
Proteome-Wide Subcellular Localization Changes. D. Itzhak,
S. Tyanova, J. Cox, M. Mann, G. Borner. Max Planck Inst. of
Biochem., Martinsried.
C117 819.4
Characterization
of
Retinal
Thickness
Measurements and Their Relationship to Visual Acuity in
Progressing Cases of Dry Macular Degeneration. B.J. Klein,
L.S. Khadjavi. Loyola Marymount Univ.
C118 819.5
Syntrophic Metabolism of Vitamins and Amino
Acids in Gut Microbial Community as Revealed by In Silico
Genomic Analyses. M.S. Khoroshkin, D. Rodionov. IITP,
Russian Acad. of Sci., Moscow and Sanford Burnham Prebys
Med. Discovery Inst., San Diego.
MONDAYBIOCHEMISTRY
C119 819.6
Global Ubiquitylome Profiling for the
Identification of Drug Targets in Cancer. N.D. Udeshi, J.
Kronke, E. Fink, T. Svinkina, M. Schenone, B. Ebert, S.A.
Carr. Broad Inst. of MIT and Harvard, Univ. Hosp. of Ulm,
Germany and Brigham and Women’s Hosp.
C120 819.7
The Transcription Factors Swi4 and Hap4
Contribute to the Regulation of the Transcriptional Response
to Cold Shock in Saccharomyces cerevisiae K.W. Wyllie, K.P.
McGee, M.V. Hong, K.D. Dahlquist. Loyola Marymount Univ.
C121 819.8
Modeling the Dynamics of a 21-Gene, 50Edge Gene Regulatory Network Controlling the Transcriptional
Response to Cold Shock in Saccharomyces cerevisiae Using
GRNmap. K.G. Johnson, N.E. Williams, B.G. Fitzpatrick,
K.D. Dahlquist. Loyola Marymount Univ.
C122 819.9
Mathematical Modeling Shows That Gln3 and
Zap1 Affect the Dynamics of the Gene Regulatory Network
Controlling the Cold Shock Response in Saccharomyces
cerevisiae T.A. Morris, K.M. Horstmann, K.C. Jackson, B.G.
Fitzpatrick, K.D. Dahlquist. Loyola Marymount Univ, CA. and
Spelman Col., GA.
C123 819.10 Test-Driven Development Improves GRNsight:
A Web Application for Visualizing Models of Gene Regulatory
Networks. A. Varshneya, N.A. Anguiano, M. Samdarshi,
J.D.N. Dionisio, B.G. Fitzpatrick, K.D. Dahlquist. Loyola
Marymount Univ.
C124 819.11 Novel Quantitative FRET Technology to
Determine Protein Interaction Dissociation Constant and
Enzymatic Kinetics in Solution for Sumoylation Cascade. J. Liao,
Z. Xiong, G. Way, V. Madarha. Univ. of California, Riverside.
C125 819.12 Novel
Mechanisms
of
Transcriptional
Regulation of Vitamin and Co-factor Metabolism in Archaea. I.A.
Rodionova, X. Li, M.W. Vetting, S.C. Almo, A.L. Osterman,
D.A. Rodionov. Sanford-Burnham-Prebys Med. Discovery
Inst. and Albert Einstein Col. of Med.
C126 819.13 Understanding
the
Lipid
Mediated
Oligomerisation in Membrane Proteins. K. Gupta, C.
Robinson. Univ. of Oxford.
C127 819.14 Information Extraction from Native Mass
Spectra. S. Guan. UCSF.
C128 819.15 Evolutionary and Comparative Genome
Analysis of Phage NAD Metabolic Genes. L. Sorci, M.D.
Kazanov, S. Gerdes. Marche Polytech Univ., Italy, Russian
Acad. of Sci., Moscow and Argonne Natl. Lab., IL.
C129 819.16 GRNmap and GRNsight: Open Source
Software for Dynamical Systems Modeling and Visualization
of Medium-Scale Gene Regulatory Networks. K.D. Dahlquist,
B.G. Fitzpatrick, J.D.N. Dionisio, N.A. Anguiano, J.S.
Carrillo, M.V. Hong, K.M. Horstmann, K.C. Jackson, K.G.
Johnson, T.A. Morris, T.A.M. Roque, M. Samdarshi, A.
Varshneya, N.E. Williams, K.W. Wyllie. Loyola Marymount
Univ., CA and Spelman Col., GA.
820.TOXICOGENOMICS
Poster
Exhibit Halls A-D
C130 820.1
Using a Toxicogenomic Approach to Understand
How Silver Poisons the Bacterial Cell. J. Lemire, K. ChatfieldReed, G. Chua, R.J. Turner. Univ. of Calgary, Canada.
821. WHOLE PROTEOME PROFILING
Poster
Exhibit Halls A-D
C131 821.1
Enhanced Sample Preparation for Proteomic
Analysis Utilizing Reversible Biotinylation and Polymer-Based
Protein Engineering. A. Lucas, C. Cummings, A. Russell, J.
Minden. Carnegie Mellon Univ.
822. MASS SPECTROMETRY
Poster
Exhibit Halls A-D
C132 822.1
LC-MS/MS Evaluation about How Lipoprotein
Lipids Are Oxidized In Vivo. S. Kato, K. Nakagawa, J. Ito,
Y. Otoki, A. Asai, M. Nagao, H. Sugihara, S. Oikawa, T.
Miyazawa. Grad. Sch. of Agr. Sci., Tohoku Univ., Nippon Med.
Sch. and NICHe, Tohoku Univ., Japan.
823.NANOTECHNOLOGY
Poster
Exhibit Halls A-D
C133 823.1
Multiplexing Metabolomic-Based Disease
Diagnosis by Surface Enhanced Raman Spectroscopy
Platform. Y. Chen, R. Premasiri, L.D. Ziegler. Boston Univ.
C134 823.2
Targeted
Drug
Delivery
System
for
Ribonuclease A. V.C. Barceló-Bovea, K. Griebenow, A. CruzMontañez. Univ. of Puerto Rico, Rio Piedras Campus.
C135 823.3
Atomic Force Microscopy Studies of
Conformational Changes in Proteins and Peptides. N.T.
Ploscariu, J. Tomich. Kansas State Univ.
C136 823.4
Absorption Mechanisms of Poly I:C RNA
Onto Zinc Oxide Nanoparticles: Maximizing the Payload. M.
Ramani, R.K. DeLong. Kansas State Univ.
824. NEW MOLECULAR AND CELLULAR
IMAGING AGENTS
Poster
Exhibit Halls A-D
C137 824.1
Molecular Design and Photophysics of
Curcuminoid Chromophores for Application as Photoacoustic
Contrast Agents. F.J. Mithila, S. Bellinger-Buckley, M.
Frenette, M. Hatamimoslehabadi, C. Yelleswarapu, J.
Rochford. Univ. of Massachusetts Boston.
C138 824.2
Characterization of Leadmium Green for
Fluorescence Detection of Intracellular Cadmium. L.M.
Malaiyandi, H. Sharthiya, K.E. Dineley. Midwestern Univ., IL.
261
M
O
N
BIOCHEMISTRYMONDAY
C139 824.3
Arc Fluorescence In Situ Hybridization in
Cleared Whole Brains Utilizing Hybridization Chain Reaction
Amplification. M. Nguyen, M.K. Chawla, C.A. Barnes. Univ.
of Arizona.
825. PROTEIN CHEMISTRY
Poster
Exhibit Halls A-D
C140 825.1
Easier Elution of Urinary Proteins Preserved
on Nitrocellulose Membrane with Heating. W. Qin. Beijing
Normal Univ.
C141 825.2
The Collection and Preservation of Urinary
Proteins Using a Special Diaper. W. Qin. Beijing Normal Univ.
C142 825.3
Development of “Inside-Out” PEGylated
Crosslinked Hemoglobin Polymers: A Novel HemoglobinBased Oxygen Carrier. K.D. Webster, D. Dahhan, C. Frosti,
W. Dean, J.B. Chaires, K.W. Olsen. Loyola Univ. Chicago and
Univ. of Louisville.
C143 825.4
Novel
Anti-cariogenic
PhosvitinPhosphopeptides Produced by Hydrostatic Pressure Combined
with Enzymatic Hydrolysis. H. Yoo. Univ. of Alberta.
826. PROTEIN/PEPTIDE SEPARATION
Poster
Exhibit Halls A-D
C144 826.1
Measurements of Endogenous Opioid Peptides
in the Rat Brain Using Online-Preservation Microdialysis with
Mass Spectrometry. D. Robles, N.D. Laude, C. Kramer, E.
Lemister, D. Meske, E. Navratilova, M. Heien, F. Porreca.
Univ. of Arizona.
827. RECOMBINANT DNA TECHNOLOGY
Poster
Exhibit Halls A-D
C145 827.1
Purification of Truncated Wild-Type and Mutant
Recombinant Lipoprotein Lipase and Investigating Their Ability
to Regulate ABCA1 K.R. Madhwani, J.D. Medh. California
State Univ., Northridge.
262
828. GENOMICS/TRANSCRIPTOMICS IN DISEASE
Poster
Exhibit Halls A-D
C146 828.1
Analysis of Myogenic Markers in Duchenne’s
Muscular Dystrophy Cell Models. M. Harnois, M. Pincus, E.
Powers, V. Badarinarayana. Univ. of Arizona and Sanofi, Oro
Valley, AZ.
C147 828.2
Characterization of Vitamin D and Serotonin
Pathway Variations in Patients with Irritable Bowel Syndrome.
C.M. Dussik, A. Grozić, M. Hockley, L. Zhang, J. Park, J.
Wang, C. Nickerson, S.H.Yale, A. Foxx-Orenstein, T. Sandrin,
P. Jurutka. Arizona State Univ., Biodesign Inst.,Tempe, North
Florida Reg. Med. Ctr., Mayo Clin. Col. of Med., Scottsdale and
Univ. of Arizona Col. of Med.
C148 828.3
Noninvasive
Detection
of
Fetal
Subchromosomal Abnormalities by Semiconductor Sequencing
of Maternal Plasma DNA. D.D. Zhang, K. Zhang. UCSD.
829. INTEGRATIVE OMICS BIOINFORMATICS
Poster
Exhibit Halls A-D
C149 829.1
Temporal Shifts in Differential Changes and
Regulatory Relations among Multi-omic Assays in Social Defeat
Mouse Model of Post-traumatic Stress Disorder. S. Muhie, A.
Gautam, N. Chakraborty, R. Hammamieh, J. Meyerhoff, M.
Jett. U.S. Army Ctr. for Envrn. Hlth. Res., Fort Detrick, MD.
830.METABOLOMICS
Poster
Exhibit Halls A-D
C150 830.1
Modification of Urinary Metabolome in Young
Women after Cranberry Juice Consumption Were Revealed
Using UHPLC-Q-Orbitrap-HRMS-based Global Metabolomics
Approach. H. Liu, T.J. Garrett, Z. Su, C. Khoo, L. Gu. Univ. of
Florida and Ocean Spray Cranberries Inc., Lakeville, ME.
C151 830.2
A Metabolomics Investigation of the
Physiological Component of the Innate Immune Response in
Raw264.7 Macrophages Treated with Nitric Oxide Inhibitors.
A. May, J. Wepy, L. Marnett. Vanderbilt Univ.
MONDAYBIOCHEMISTRY
831.OMICS
Poster
Exhibit Halls A-D
C152 831.1
Simultaneously Revealing All Lysine Acylations
in an Organism to Elucidate Substrate Metabolism. H.H.T.
Nguyen, J.A. Loo, R.R. Ogorzalek Loo. UCLA.
C153 831.2
Identification of Apoptosis Inducing Signaling
Pathways and Characterization of Sclerotium rolfsii lectin
(SRL) Binding Proteins from Human Colon Epithelial Cancer
HT29 Cells. N. Guha, R. Gudihal, S. Barkeer, D. SA, A.
Padmanaban, S. Inamdar. Agilent Technologies,Bangalore
and Karnatak Univ., India.
C154 831.3
Characterization of the Epigenomic Status
of the U.S. OEF/OIF War Veterans: A Pilot Clinical Study. N.
Chakraborty, S. Muhie, R. Yang, A. Gautam, D. Donohue,
B. Daigel, Y. Zhang, D.A. Amara, J. Flory, R. Yehuda, F.
Doyle, R. Hammamieh, C. Marmar, M. Jett. U.S. Army Ctr. for
Envrn. Hlth. Res., Frederick, NCI-Frederick, Univ. of California,
Santa Barbara, NYU Sch. of Med. and Icahn Sch. of Med. at
Mount Sinai.
C155 831.4
Omics Approaches for Discovery of Natural
Anti-aging and Anti-cancer Compounds and Defining
Mechanisms of Their Action. V. Titorenko, A. Leonov, A. ArliaCiommo, Y. Medkour, V. Svistkova. Concordia Univ., Montreal.
832. OMICS AND THE DEVELOPMENT OF
PERSONALIZED MEDICINE
Poster
Exhibit Halls A-D
C156 832.1
Genomics of Gastrointestinal Disorders: A
Familial Based Approach. J.L. Coble, K. Sheldon, F. Yue,
L. Schneper, C. Choi, K. Poirier, T. Salameh, L. Harris, S.
Deiling, F. Ruggiero, J.R. Broach, W.A. Koltun, G.S. Gerhard.
Penn State, Hershey and Temple Univ. Col. of Med.
833. ENZYME DYNAMICS AND ENZYME MOTIONS
Poster
Exhibit Halls A-D
C157 833.1
Investigating the Role of the Primer-Template
Terminus in the Conformational Dynamics of Bacillus
stearothermophilus DNA Polymerase I Using FRET. T.D.
Christian, W. Konigsberg. Yale Univ.
C158 833.2
Cytotoxicity of Calpain Inhibitor KR-180 R.
Alzahrani, A. Baashirah, E. Myles, I. Donkor, W. Boadi, X.
Wang. Tennessee State Univ. and Univ. of Tennessee Hlth.
Sci. Ctr.
C159 833.3
Evolution of Phospholipases A2 in Catalysis
and Allosteric Regulation by Membranes. V.D. Mouchlis, J.A.
McCammon, E.A. Dennis. UCSD.
C160 833.4
Ramachandran Outliers in Ligand-Induced
Protein Structural Changes. K.H.J. West, W.R.P. Novak.
Wabash Col., IN.
C161 833.5
Conservative Substitutions of Buried Amino
Acid Residues Distant from the Active Site of Horse Liver
Alcohol Dehydrogenase Have Small Effects on Structure,
Catalysis and Dynamics. B.V. Plapp, K. Shanmuganatham,
R.S. Wallace, A.T-I. Lee. Univ. of Iowa.
C162 833.6
Large Scale Structural Rearrangement
Provides Dual Control Over the Catalytic and Membrane
Binding Activity of a Bacterial Serine Hydrolase. R.J. Johnson,
M. Smith, W. Hart. Butler Univ.
C163 833.7
Dynamic Equilibria Studies of FTT258, a
Serine Hydrolase from Francisella tularensis P. Rabin, R.J.
Johnson. Butler Univ.
C164 833.8
Dissociation
Constants
for
Reversible
Homodimers
of
Recombinant
Monomeric
Human
Acetylcholinesterase. Z. Radic. Skaggs Sch. of Pharm. and
Pharmaceut. Sci., UCSD.
C165 833.9
Overlay
Independent
Comparison
of
Acetylcholinesterase 3D Structures Reveals Ligand-Specific
Backbone Changes upon Reversible and Covalent Binding. Z.
Radic, J. Rohrer, M. Sidhom, J. Han. Skaggs Sch. of Pharm.
and Pharmaceut. Sci., UCSD.
C166 833.10 Structural and Functional Analysis of
Acetylcholinesterase Complexes with In Situ Click-Chemistry
Inhibitors. P. Marchot, K.B. Sharpless, P. Taylor, Y. Bourne.
CNRS, Aix-Marseille Univ, The Scripps Res. Inst. and Skaggs
Sch. of Pharm. and Pharmaceut. Sci., UCSD.
834. ENZYME KINETICS
Poster
Exhibit Halls A-D
C167 834.1
Structural, Biochemical Characterization, and
Evolutionary Origin of Alcohol/Aldehyde Dehydrogenases in
Entamoeba J. Leitao, A. Espinosa. Roger Williams Univ.
C168 834.2
Biochemical
Characterization
of
Two
Evolutionary Distant Ten-Eleven Translocation Enzymes and
Their Utility in 5-Methylcytosine Sequencing in the Genomes
at Single-Base Resolution. L. Saleh, E. Tamanaha, R. Vaisvila,
J.E. Pais, N. Dai, S. Guan, I.R. Corrêa; Jr., Y. Zheng. New
England Biolabs.
C169 834.3
Evaluating the Catalytic Role of a Conserved
Glutamate Residue in Triosephosphate Isomerase. N.
Seangmany, A. Nguyen, A. Chan, J. Schwans. California
State Univ., Long Beach.
C170 834.4
Expression, Purification and Enzymatic
Characterization of Brugia malayi Dihydrofolate Reductase. R.
Perez-Abraham. Montclair State Univ., NJ.
C171 834.5
Kinetics and Binding Studies Reveal That
His-40 Is Essential for Catalysis in F420-Dependent Glucose-6Phosphate Dehydrogenase from Mycobacterium tuberculosis
M. Oyugi, J. Mayfield, G. Bashiri, E. Baker, Y. Zhang, K.
Johnson-Winters. Univ. of Texas at Arlington, Univ. of Texas
at Austin and Univ. of Auckland.
C172 834.6Withdrawn
C173 834.7
A New Role of Cysteine Residues in
Human H-Ferritin Activity. J.Y. Yeom. Ewha Womans Univ.,
South Korea.
263
M
O
N
BIOCHEMISTRYMONDAY
C174 834.8
Characterization of a Novel Flavin-Dependent
Monooxygenase in Bacillus niacini M.A. Dasovich, M.J.
Snider, M.T. Peterson. The Col. of Wooster, OH.
C175 834.9
Characterization
and
Identification
of
Metabolites in the Oxidation of Nicotinic Acid by Bacillus
niacini N.P. Lesner, M.T. Peterson, M.J. Snider. The Col. of
Wooster, OH.
C176 834.10 Biodiesel Production via Genetically Altered
Lipase from Proteus mirabilis Transesterification in Methyl
Acetate. A.N. McDonnell, J. Altier, D. Carey, D.S. Witherow.
Univ. of Tampa.
C177 834.11 Coevolution and Disease-Causing Mutations
in Glucose-6-Phosphate Dehydrogenase. A. Cunningham, A.
Colavin, KC. Huang, D. Mochly-Rosen. Stanford Univ.
C178 834.12 Mutational Analysis of the Catalytic Mechanism
of a Peroxidase Enzyme from the Diatom Thalassiosira
pseudonana E. Bordeaux, S. Rampur, K. Frato. Seattle Univ.
C179 834.13 Understanding the Ability of Heavily
Contaminated Soil to Sustain Enzyme Function. D. LeRoux.
Montclair State Univ.
C180 834.14 Fluorescent Assay of Ubiquitin Conjugation. C.
Jackson, C. Berndsen. James Madison Univ.
C181 834.15 Transition Metal Cation Inhibition of
Mycobacterium tuberculosis Esterase Rv0045c. B. Lancaster,
G. Hoops, R.J. Johnson. Butler Univ.
C182 834.16 Structural and Biochemical Characterization of
AidC, a Quorum-Quenching Lactonase with Atypical Selectivity.
R.N. Mascarenhas. Loyola Univ. Chicago.
C183 834.17 Fluorophore Conjugation to Substrates Affects
Lysine Deacetylase Activity and Specificity. T.B. Toro, T.J. Watt.
C184 834.18 Probing the Role of a Catalytic Residue in a
Lysine Deacetylase. K.A. Nichols, T.B. Toro, T.J. Watt. Xavier
Univ. of Louisiana.
C185 834.19 Impact of a KDAC4 Active Site Residue on
Activity and Specificity. J.R. Bryant, T.B. Toro, T.J. Watt. Xavier
Univ. of Louisiana.
C186 834.20 Substrate Specificity of the Rv0045c Hydrolase
from Mycobacterium tuberculosis G.C. Hoops, A.D. White,
R.J. Johnson. Butler Univ.
C187 834.21 Investigating the Half-Site Reactivity of a
Member of the PNDOR Family of Proteins. W. Li, D. To, J. Lee,
E.J. Crane, M. Sazinsky. Pomona Col., CA.
C188 834.22 The Role of Aspartate 141 in the Regulation of
the Agrobacterium tumefaciens ADP-Glc Pyrophosphorylase.
H.P. Patel, L. Gonzalez-Martin, V. Renata, M. Ballicora.
Loyola Univ. of Chicago.
835. REGULATION AND ALLOSTERISM
Poster
Exhibit Halls A-D
C189 835.1
Examination of the Mechanism of Intersubunit
Communication in Pyruvate Carboxylase Using Mixed Hybrid
Tetramers. L.E. Westerhold, T.N. Zeczycki. Brody Sch. of
Med. at East Carolina Univ.
C190 835.2
Control of Enzyme Function through Loop
Dynamics. C.N. Chi, B. Vogeli, S. Bibow. ETH, Zurich.
264
C191 835.3
Structure-Function Studies of ADPGlucose
Pyrophosphorylase from Thermodesulfovibrio yellowstonii:
Probing the Role of the C-Terminus in Allosteric Regulation. S.
Kaur, A. Avila, A. Espinoza, L. Mulato, J. Chan, M. Susoeff,
C.R. Meyer. California State Univ., Fullerton.
C192 835.4
Probing the Role of the N-Terminus in the
ADP-Glucose Pyrophosphorylase from Thermodesulfovibrio
yellowstonii E. Yik, E. Pushkarev, D. Campbell, C. Diep, N.
Duran, J. Nguyen, A. Orry, C.R. Meyer. California State Univ.,
Fullerton and Molsoft LLC, San Diego.
C193 835.5
Structure-Function Studies of the ADPglucose
Pyrophosphorylase from Agrobacterium tumefaciens: Defining
the Roles of the K310 and P288 Residues in Allosteric
Regulation. V. Duong, J. Butz, T. Nguyen, J. Ochoa, C.R.
Meyer. California State Univ., Fullerton.
C194 835.6
Decoupling the Allosteric Activation of Ubiquitin
Specific Protease 7 by Its Ubiquitin-Like Domains for the
Development of Small Molecule Inhibitors. N.M. Hjortland,
A. Pepe, K. Molland, A. Mesecar. Purdue Univ. and Cook
Biotech, West Lafayette.
C195 835.7
Unexpected pH-Dependent DNA Binding of
CooA, a CO-Sensing Transcription Factor from Rhodospirillum
rubrum B.R. Weaver, R.M. DeVries, A.J. Gunter, R.W. Clark.
Valparaiso Univ.
C196 835.8
The Agrobacterium tumefaciens ADP-Glucose
Pyrophosphorylase G329D Mutant Exists in a Pre-activated
State. B.L. Hill, R. Mascarenhas, A.M. Koenig, F. Huerta,
S. Khan, A.A. Iglesias, D. Liu, M. Ballicora. Loyola Univ.
Chicago and Univ. of Buenos Aires.
C197 835.9
Regulation of N-Myristoyltransferase by Akt/
PKB Mediated Phosphorylation. S. Kumar, R.K. Sharma. Col.
of Med., Univ. of Saskatchewan.
C198 835.10 Dynamic Flexibility of p97 AAA ATPase Is
Important for Cofactor Regulation. T-F. Chou. Harbor-UCLA
and LABioMed, Torrance.
C199 835.11 Probing the Role of Threonine-221 and
Lysine-397 in ADP-Glucose Pyrophosphorylase from
Deinococcus radiodurans J. Reynaga, G. Szczeblowski,
C. Salas, A. Le-Pham, L. Ong, C.R. Meyer. California State
Univ., Fullerton.
C200 835.12 Structure-Function Studies of Deinococcus
radiodurans ADP Glucose Pyrophosphorylase: Role of Ser48
in Allosteric Regulation. A. Le-Pham, J. Qoborsi, L. Ong, A.
Orry, C.R. Meyer. California State Univ., Fullerton and Molsoft
LLC, San Diego.
C201 835.13 Structure-Function Studies of the Thermotoga
maritima ADPGlucose Pyrophosphorylase: Probing the Role
of the C-Terminus of the GlgD Subunit. J. Tiet, A. Kuipers, C.
Vu, A. Orry, C.R. Meyer. California State Univ., Fullerton and
Molsoft LLC, San Diego.
C202 835.14 Phosphorylation Site Specificity for 14-3-3
Protein Binding to Tyrosine Hydroxylase Studied by Chemical
Cross-Linking. S.C. Daubner, E.J. Vogt, S. Mallet. St. Mary’s
Univ., TX.
C203 835.15 Regulation of Tyrosine Hydroxylase Studied by
Fluorescence Anistotropy and Fluorescent Resonance Energy
Transfer. S.C. Daubner, L. Teran, A. Rodriguez, E. Cruz. St.
Mary’s Univ., TX.
MONDAYBIOCHEMISTRY
836. STRUCTURAL ENZYMOLOGY
Poster
Exhibit Halls A-D
C204 836.1
Modification of the Flexible Loop of Tyrosine
Hydroxylase That Determines Substrate Specificity. S.C.
Daubner, S. Rios. St. Mary’s Univ.
C205 836.2
Structural Basis for Weight Loss in Patients
with Chronic Obstructive Pulmonary Disease: Modeling of
Gly80 and Ser80 Variants of Human Group IID Phospholipase
A2 and Their Receptor Complexes. G. Hariprasad, A.S.
Ethayathulla, M.I. Khan. All India Inst. of Med. Sci., New Delhi.
C206 836.3
Structural Insights Into Novel Esterase. S.
Rhee, S. Kim. Seoul Natl. Univ.
C207 836.4
Determining the Structure of NRPSIndependent Siderophore Synthetase DesD Using X-Ray
Crystallography. K.L. Karimi, K.M. Hoffmann. California
Lutheran Univ.
C208 836.5
Structural and Functional Substrate Binding in
an Iterative Non-ribosomal Peptide Synthetase Independent
Siderophore Enzyme from Streptomyces coelicolor K.M.
Hoffmann. California Lutheran Univ.
C209 836.6
Structural Characterization of SOD5 Mutants
from Candida albicans J. Villarreal, R.L. Peterson, A.B.
Taylor, S.P. Holloway, A. Galaleldeen, V.C. Culotta, P.J. Hart.
St. Mary’s Univ., TX, Johns Hopkins Bloomberg Sch. of Publ.
Hlth. and Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
C210 836.7
Engineering a Putative Zinc Binding Site in
SO. D5 C. Moreno Romero, R.L. Peterson, A.B. Taylor, S.P.
Holloway, A. Galaleldeen, V.C. Culotta, P.J. Hart. St. Mary’s
Univ., TX, Johns Hopkins Bloomberg Sch. of Publ. Hlth. and
Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
837. STRUCTURAL ENZYMOLOGY OF
MEMBRANE PROTEINS
Poster
Exhibit Halls A-D
C211 837.1
Human Alpha3 Beta1 Isoform of Na+/K+ATPase: Expression in Yeast, Mutations and Their Relation to
Neurological Disorders. J. Geletičová, M. Kubala, D. Sorensen,
P.A. Pedersen, P. Nissen. Palacky Univ. in Olomouc, Czech
Republic, Univ. of Copenhagen and Aarhus Univ., Denmark.
838. BIOCATALYSIS, BIOENERGY,
AND BIORENEWABLES
Poster
Exhibit Halls A-D
C212 838.1
Molecular Cloning and Expression of a Putative
Oleate Hydratase Isozyme from Nocardia cholesterolicum
NRRL 5767
J-K. Huang, H.B. Alhmadi, D.R. Vanderway,
C.A. Hoerner, L. Wen. Western Illinois Univ.
C213 838.2
Molecular Cloning and Expression of an Oleate
Hydratase from Nocardia cholesterolicum NRRL 5767 D.R.
Vanderway, H.B. Alhmadi, J.D. Diaz, L. Wen, J-K. Huang.
Western Illinois Univ.
C214 838.3
Molecular Cloning and Expression of
a Secondary Alcohol Dehydrogenase from Nocardia
cholesterolicum NRRL 5767 J.D. Diaz, D.R. Vanderway, M.
Flores, L. Wen, J-Q. Huang. Western Illinois Univ.
C215 838.4
The Energetic Cost of Improved Acid
Resistance. E.C. Keffeler, S. Payne, P. Blum. Missouri
Western State Univ. and Univ. of Nebraska-Lincoln.
C216 838.5
Optimization and Lipid Quantitation of Potential
Algal Biofuels Feedstocks. S.J. Brad, B.E. Umbach, E.D.
Gehlhausen, C.R. Sweet. U.S. Naval Acad., Annapolis.
C217 838.6
Correlating Gene Expression Profiles to Lipid
Induction in the Microalga Chlorella protothecoides R.S.J.
Maggard, R.L. Waikel. Eastern Kentucky Univ.
839. BIOSYNTHESIS OF COMPLEX MOLECULES
Poster
Exhibit Halls A-D
C218 839.1
Substrate Synthesis and Inhibitor Design
for Synthetase DesD from Streptomyces coelicolor B.A.
Smolarski, H.J. Adetyan, J.S. Kingsbury, K.M. Hoffmann.
California Lutheran Univ.
840. CHEMICAL BIOLOGY
Poster
Exhibit Halls A-D
C219 840.1
Strategies to Enable Practical Electrochemical
Diagnostics for Proteins and Small Molecules. A.J. Bonham,
A. Bulow, L.C. Fetter, J. Richards, J. Daniel, M. McCoy.
Metropolitan State Univ. of Denver.
C220 840.2
Design of a Genetically Encoded 4Fe-4S
Cluster Sensor. C. Glynn, J.D. Grossman, D. Perlstein.
Boston Univ.
265
M
O
N
BIOCHEMISTRYMONDAY
841. CHEMISTRY AND CELL BIOLOGY OF
NATURAL PRODUCTS
Poster
Exhibit Halls A-D
C221 841.1
Skin Preparations from Catfish (Arius
bilineatus, Val.) Contain a Lipid Which Inhibits Cancer Cell
Survival In Vitro. J.M. Al-Hassan, M. Afzal, B.M. Paul, S.
Oommen, Y.F. Liu, C. Pace-Asciak. Kuwait Univ., CMS Col.
Kottayam, India and Univ. of Toronto Sick Kids Hosp. Res. Inst.
C222 841.2
Uranyl Ion Biosensors for Water Quality and
Safety. S.J. Jett, A.J. Bonham. Metropolitan State Univ.
of Denver.
C223 841.3
Antioxidant Activity of the Hexanic Extract from
Eryngium Carlinae In Vitro and in Saccharomyces cerevisiae
D. Peña-Montes, J. Mejía-Barajas, M. Clemente-Guerrero,
R. Salgado-Garciglia, C. Cortés-Rojo, R. Montoya-Pérez,
S. Manzo-Avalos, A. Saavedra-Molina. Univ. Michoacana de
San Nicolás de Hidalgo, Mexico.
C224 841.4
Antioxidant Activity of the Seed Oil Extract from
Eryngium carlinae In Vitro and in Saccharomyces cerevisiae
J.A. Mejía-Barajas, A.L. Rodríguez-Lino, R. Torres-Martínez,
R. Salgado-Garciglia, C. Cortés-Rojo, R. Montoya-Pérez,
A. Saavedra-Molina. Univ. Michoacana de San Nicolás de
Hidalgo, Mexico.
C225 841.5
Antiproliferative Effect of Curcumin and
Kaempferol on Colon Cancer Cells. A. Kaverimanian, N.
Khatwani, U. Ezekiel. Saint Louis Univ.
C225A 841.6
Amino Acid Selection during Teicoplanin
Biosynthesis Can Be Switched by a Point Mutation. T. Kittilä,
M.J. Cryle. Max Planck Inst. for Med. Res., Heidelberg and
EMBL, Monash Univ., Australia.
842. DRUG DISCOVERY
Poster
Exhibit Halls A-D
C226 842.1
Biological, Electrochemical and Spectroscopic
Study of Cu (II) Complexes: Applications to the Development of
Anticancer Metallodrugs. A. Lewis, K. Fox, J. Tanski, L. Tyler.
Union Col. and Vassar Col.
C227 842.2
Docking into Homology Models in Tandem
with Structure Activity Relationships: Bradykinin B2 Receptor
Complexed with Non-opioid Dynorphin A Analogues. C. Chan,
Y. Lee, V. Hruby. Univ. of Arizona.
C228 842.3
Antiproliferative Effects of Hinute-AM in Human
Breast Cancer Cell Lines. S. Mukherjee, P. Mitra, A. Ratna, M.
Maebuchi, H. Furuta, S.K. Das. Meharry Med. Col. and Fuji
OIl Co., Ibaraki,Japan.
C229 842.4
Design, Synthesis, and Development of Broad
Spectrum Coronaviral 3C-Like Protease Inhibitors to Target
Emerging Human Pathogens: A Phylochemical Approach. S.E.
St. John, A.D. Mesecar. Purdue Univ.
266
C230 842.5
Organic Synthesis of Novel Phosphatidylinositol
3-Kinase Inhibitors Activated by Prostate-Specific Antigen for
the Treatment of Androgen-Independent Prostate Cancer. R.A.
Nelson. Wake Forest Univ.
C231 842.6
The Structural Basis of Cyclooxygenase-2
Inhibition by Fenamates. S. Xu, S. Banerjee, S.N. Kudalkar,
E.T. Perry, K. Ghebreselasie, L.J. Marnett. Vanderbilt Univ.,
Argonne Natl. Lab. and Cornell Univ.
C232 842.7
Engineered FGF-1 Derivatives Lacking
Cysteine for Treating Corneal Endothelial Dystrophy. D.
Eveleth, R. Bradshaw, M. Blaber. Trefoil Therapeut. LLC, San
Diego and Florida State Univ.
C233 842.8
L- to D- Amino Acid Substitution Impacts the
Cellular Penetration Activity and the Intracellular Behavior of
the Endosomolytic Delivery Agent dfTAT. K. Najjar, A. ErazoOliveras, J-P. Pellois. Texas A&M Univ.
C234 842.9
Late Endosomes and Its Unique Anionic Lipid
bis(Monoacylglycero)phosphate Act as Doorways for the
Endosomal Escape and Cytosolic Entry of the FluorescentlyLabeled Dimeric Cell-Penetrating Peptide dfTAT and Bioactive
Cargos. A. Erazo-Oliveras, K. Najjar, D. Truong, T-Y. Wang,
J-P. Pellois. Texas A&M Univ.
C234A 842.10 Engineered
Caspases
with
Altered
Specificities Enable Identification of Exosites. J.A. Hardy, M.
Hill, D.J. MacPherson, P. Wu, O. Julien, J.A. Wells. Univ. of
Massachusetts Amherst and UCSF.
843. ENZYMOLOGY OF GLYCOSYL-TRANSFERASES
AND HYDROLASES
Poster
Exhibit Halls A-D
C235 843.1
Biophysical and Biochemical Analyses of
Cellulase-Polymer Bioconjugates for Biofuel Applications. K.
Makaroff, M. Lucius, T. Wright, J. Stewart, C. Williams, J.
Berberich, D. Konkolewicz, R.C. Page. Miami Univ.
C236 843.2
Mutagenesis Study to Reveal Important
Determinants of XXT2 Catalytic Activity. A.L. Smith, A.T.
Culbertson, O.A. Zabotina. Iowa State Univ.
C237 843.3
Optimizing a Chemoenzymatic Method to
Produce a Photocrosslinking Nucleotide Donor Sugar for the N.
meningitidis Serogroup W Capsule Polymerase. C. Gonzalez.
Morgan State Univ. C237A 843.4
Structure and Biosynthesis of Complex
N-Glycan Cores and Antennae in Nematodes. I.B.H. Wilson,
S. Yan, K. Paschinger. Univ. of Nat. Resources and Life Sci.,
Vienna.
C237B 843.5
Bacterial Glycosidases Acting on Red Blood
Cells. Y. Bourne, G. Ponchel, V. Roig-Zamboni, E.P. Bennett,
B. Henrissat, H. Clausen, G. Sulzenbacher. CNRS, AixMarseille Univ. and Copenhagen Ctr. for Glycomics.
MONDAYBIOCHEMISTRY
844.N-GLYCOSYLATION
848. MECHANISTICALLY-INFORMED DRUG DESIGN
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C238 844.1
Silencing Mannosylphospho Dolichol Synthase
with shRNA Impacts Differentiation of Capillary Endothelial
Cells. K. Baksi, Z. Zhang, A. Banerjee, J.E. Serrano, L.E.
Perez, L. Linares, A. Seijo, N. Sanchez, U. Katiyar, D.K.
Banerjee. Univ. Central del Caribe and Univ. of Puerto Rico.
C239 844.2
Analysis of Vascular Endothelial Growth Factor
Receptor 2 Glycosylation and Its Role in Angiogenesis. K.B.
Chandler, K. Khatri, D.R. Leon, R.D. Meyer, N. Rahimi, C.E.
Costello. Boston Univ. Sch. of Med.
845.O-GLCNAC
Poster
Exhibit Halls A-D
C239A 845.1
Elevated O-GlcNAcylation Levels Improve
Mitochondrial Function. E.P. Tan, R. Swerdlow, C. Slawson.
Univ. of Kansas Med. Ctr.
C239B 845.2
O-GlcNAcylation of the Human Kinome. X.
Liu, G. Han, L. Wells, L. Graves, H. Zhu, J. Neiswinger, G.W.
Hart. Johns Hopkins Univ., Univ. of Gerogia and Univ. of Illinois
846.O-GLYCOSYLATION
Poster
Exhibit Halls A-D
C239C 846.1
Defects in Protein O-Mannosylation Result in
Abnormal Muscle Contractions and Aberrant Neural Sensory
Feedback in Drosophila. V. Panin, R. Baker, N. Nakamura, D.
Lyalin. Texas A&M Univ.
847. SIGNALING IN GLYCOBIOLOGY
Poster
Exhibit Halls A-D
C240 847.1
Lectin-Based
Methods
for
In
Vivo
Characterization of C-Mannosylated Proteins. N.R. Kegley, S.
Naylor, J. Rakus. Marshall Univ.
C240A 847.2
Lectin Nucleotide Phosphohydrolases May
Function as Co-receptors or Modulators of Several ChitinBased Oligosaccharide Signaling Events in Plants. M.E.
Etzler, N. Roberts, G. Kalsi. Univ. of California, Davis,
AgRes. Grasslands Res. Ctr., New Zealand and ITC Ltd.,
Bengaluru, India.
C241 848.1
Heterologous
Expression
of
Multidrug
Resistance Proteins. C.A. Marchesseault, P.D. Vogel, J.G.
Wise. So. Methodist Univ.
C242 848.2
Correlating the Reversal of Multidrug
Resistance in Cancers by Novel P-Glycoprotein Inhibitors to the
Expression of ABC Transporters. A.L. Sunshine, C.A. Follit,
C. Marchesseault, J.G. Wise, P.D. Vogel. So. Methodist Univ.
C243 848.3
Inhibition of ABC-Transporters by In Silico
Identified Small Molecules. C.A. Follit, A.K. Nanayakkara,
J.G. Wise, P.D. Vogel. So. Methodist Univ.
C244 848.4
Functional Reconstitution of P-Glycoprotein
Into Nanodiscs: Biochemical and Biophysical Evaluation. G.
Chen, M. Oliveira, J.G. Wise, P.D. Vogel. So. Methodist Univ.
C245 848.5
In Silico Selective Screening for Inhibitors of
ABC Transporters That Minimizes Off Target Toxicity. J.W.
McCormick, C.A. Follit, P.D. Vogel, J.G. Wise. So. Methodist
Univ.
C245A.848.6
Potent Lipidated Antagonists to ProteaseActivated Receptor 2
S. Boitano, J. Hoffman, A. Flynn, C.L. Sherwood, Z. Zhang, R.
Patek, T.J. Price, J. Vagner. Univ. of Arizona and Univ. of Texas
at Dallas, Richardson.
849. METABOLIC NETWORKS
Poster
Exhibit Halls A-D
C246 849.1
De Novo Synthesis from Tryptophan in
the Absence of a QPRTase Homolog Contributes to NAD+
Biosynthesis in C. elegans M.R. McReynolds, W. Wang, L.
Holleran, W. Hanna-Rose. Penn State.
850. METABOLIC REGULATION
Poster
Exhibit Halls A-D
C247 850.1
The Ins and Outs of Regulating Gln3, the Major
Nitrogen-Responsive Transcription Activator in Saccharomyces
cerevisiae T.G. Cooper, R. Rai, J.J. Tate. Univ. of Tennessee
Hlth. Sci. Ctr., Memphis.
C248 850.2
The Four Faces of Gln3 and Its Response to
Nitrogen Catabolite Repression. T.G. Cooper, J.J. Tate, R. Rai.
Univ. of Tennessee Hlth. Sci. Ctr., Memphis.
C249 850.3
Altered Zinc Ion Levels and Transporter
Expression Indicate That High Liver Copper Disrupts Zinc
Metabolism in the Atp7b-/- Mouse Model of Wilson Disease. K.
Meacham, J. Burkhead. Univ. of Alaska Anchorage.
267
M
O
N
BIOCHEMISTRYMONDAY
C250 850.4
Hepatic Nuclear Factor 4 Alpha Regulates
Transcriptional Control of Amino Acid Catabolism. S. Tobon,
L.A. Velazquez-Villegas, V. Ortiz, N. Torres, A.R. Tovar.
UNAM and Salvador Zubiran Natl. Inst. of Hlth. Sci. and Nutr.,
Mexico City.
C251 850.5
Inhibition of Angiotensin Converting Enzyme
Induces Beige Adipocytes through Angiotensin-(1-7) in
3T1-L1 Adipocytes and Obese Mice. A.E. Vargas-Castillo,
L. Del Valle-Mondragon, N. Torres, E. Hong, A.R. Tovar.
CINVESTAV, IPN, Salvador Zubiran Natl. Inst. of Hlth. Sci. and
Nutr. and Natl. Inst. of Cardiol., Mexico City.
C252 850.6
GPR109a Signaling Alters the Hepatic
Response to Fasting. C.E. Foy, C. Hepler, B.J. Renquist.
Univ. of Arizona and Univ. of Texas Southwestern Med. Ctr.
C253 850.7
Effect of Frequent Intake of Sweeteners on the
JAK2/STAT3 Signaling Pathway in the Central Nervous System
of Mice. A.A. Barrios, I. Contreras, J.A. Estrada. Autonomous
Univ. of State of Mexico, Toluca.
C254 850.8
Mitochondrial Translocator Protein (TSPO) Is
a Regulator of Fatty Acid Metabolism. L.N. Tu, A.H. Zhao, M.
Hussein, V. Selvaraj. Cornell Univ.
C255 850.9
Sequestration-Mediated Downregulation of de
Novo Purine Biosynthesis by AMPK. D.L. Schmitt, S. An. Univ.
of Maryland Baltimore County.
C256 850.10 Chronic Caloric Restriction Alters Nutrient
Sensing in Skeletal Muscle in High-Fat Diet Fed Rats. D.
Hernandez-Saavedra, H. Chen, Y-X. Pan. Univ. of Illinois
C257 850.11 Life Long High Fat Diet Causes Hepatic Lipid
Accumulation by Programming Lipid Synthesis Genes in Liver
of Male Rat. P.M. Jung, D. Zhou, L. Moody, A. Kriska, H.
Chen, Y-X. Pan. Univ. of Illinois at Urbana-Champaign and
Mayo Clin.
851. METABOLISM AND DIABETES
Poster
Exhibit Halls A-D
C258 851.1
Activation of Adiponectin Receptors induces
Proprotein Convertase Subtilisin Kexin Type 9 Expression by
Activating PPARgamma Pathway. L. Sun, X. Yang, Y. Liu, Y.
Chen, J. Han, Y. Duan. Nankai Univ., China.
C259 851.2
Antidiabetic Effect of the Ethanolic Extracts of
Azadirachta indica Leaves on Streptozotocin-Induced Wistar
Rats. E.L. Aniefuna, O. Omorevbarhia. Ministry of Sci. and
Technol. and Nnamdi Azikiwe Univ., Awka, Nigeria.
C260 851.3
Hyperglycemia
Is
Exacerbated
by
Dysregulation of Hepatic SREBP1c-CRY1 Signaling Pathway.
J.B. Kim, W.G. Choi, H. Jang, G.Y. Lee, G. Lee, Y.G. Jeon.
Sch. of Biol. Sci., Seoul Natl. Univ.
C261 851.4
Determining the Role of Skeletal Muscle
MicroRNA-133a in Early-Onset Insulin Resistance. S. da
Silva Rosa, W. Mughal, L. Nguyen, D. Chapman, M. Aliani,
T. Pereira, C. Rampitsch, V. Dolinsky, J. Gordon. Children’s
Hosp. Res. Inst. of Manitoba, Univ. of Manitoba and Agr. and
Agrifood Canada, Morden, MB.
C262 851.5
Placental Expression of NFAT5, SLC5A3, and
Aldose Reductase in Gestational Diabetes Mellitus. C. Mejia,
P.R. Reynolds, J.A. Arroyo. Brigham Young Univ.
268
C263 851.6
Treatment with Diet or Insulin Induces a
Different Placental Ceramide Expression during Gestational
Diabetes Mellitus. C.A. Mejia, T. Monson, C. Jordan, B.T.
Bikman, P.R. Reynolds, J.A. Arroyo. Brigham Young Univ.
C264 851.7
Conjugated Linoleic Acids (CLA) and Insulin
Resistance: Differential Effects of CLA Isomers on Endoplasmic
Reticulum Stress. J.K. Dammanahalli, P.V. Subbaiah. Univ. of
Illinois at Chicago and Jesse Brown VA Med. Ctr.
C265 851.8
Decreasing O-GlcNAc Levels Reverses
Diabetic Nephropathy-Associated Phenotypes. S. Peterson,
M. Delannoy, P. Banerjee, G. Hart. Johns Hopkins Univ.
C266 851.9
Molecular Mechanism of Insulin Resistance
in Offspring of Obese Fathers. X. Liu, J. Ozbolt, R. Fuchs, Y.
Zhang, L. Consitt, Y. Slyvka, F. Nowak. Ohio Univ.
C267 851.10 Plasma Concentrations of FAM3D Protein Is
Higher in Individuals with Type 2 Diabetes Mellitus Treated with
Sulfonylureas. J.A.J. Neves, R. Feliciano, D. Giannella-Neto.
Univ. Nove De Julho, São Paulo.
C268 851.11 Liraglutide Induces Brown Adipocyte Specific
Genes in Mice Skeletal Muscle Tissue. L. Li, J.Y. Zhou, J.
Bahaee. Central Michigan Univ. and McGill Univ.
C269 851.12 Robust Glucose and 1,5-Anhydroglucitol
Uptake Assays Using Novel Fluorescent Conjugates. S.
Li, S. Khatwani, Y. Lin, G. Tchaga, G. Yan. Biovision Inc.,
Milpitas, CA.
C270 851.13 Investigating the Regulation of GuanylateBinding Protein1 Expression during Adipose Tissue
Inflammation. X. Qiu, X. Chen. Univ. of Minnesota-Twin Cities.
C271 851.14 Effects of Aqueous Cinnamon Extract on 3T3L1 Cell Size, Lipid Volume and Lipase Activity. A. Stockert,
S. Newstead, E. Freeh, M. Stephan, A. Aulthouse. Ohio
Northern Univ.
C272 851.15 Effects of Thymol on 3T3-L1 Differentiation
and Lipase Activity. O. Dinsmore, E. Wells, A. Aulthouse, A.
Stockert. Ohio Northern Univ.
C273 851.16 Effects of Paternal High Fat Diet on Plasma
Leptin, Adiponectin, and Insulin in Offspring of C57BL/6 Mice.
A. Zontini, Y. Slyvka, Y. Zhang, F.V. Nowak. Ohio Univ.
C274 851.17 Comparison of a Novel Commercial
Immunoassay, AGILE Research, and the Meso Scale
Discovery Array System for the Quantification of Insulin and
Leptin in Human Plasma. S. Afsahi, A. Walker, D. Pan, M.
Lerner, D.D. Sears, B. Goldsmith, F.E. Barron. Nanomed.
Diagnostics Inc., San Diego and UCSD.
C275 851.18 Correlation between Tau Accumulation in Brain
and Retina of Individuals with Late Stage Alzheimer’s Disease.
V. Bondarenko, D. Skyba. Touro Univ. Nevada.
852. HUMAN MICROBIOME
Poster
Exhibit Halls A-D
C276 852.1
In Vivo Efficacy and Durability of Anti-infective
Foley Catheters Functionalized with Silver Nano Particle
and Antibiotics. K.P. Srinivasakumar, R. Mala, A. Aglin, S.
Kiruthika, C. VazagaPriya. Inbiotics, India and Mepco Schlenk
Engineering Col., India.
MONDAYBIOCHEMISTRY
C277 852.2
Patterns of 16s rRNA Microbial Regions in
Aggressor-Exposed Mice with Features of Post-traumatic
Stress Disorder. A. Gautam, A. Hoke, R. Kumar, N.
Chakraborty, S. Muhie, R. Hammamieh, M. Jett. The Geneva
Fndn., Frederick Natl. Lab. for Cancer Res. and U.S. Army Ctr.
for Envrn. Hlth. Res., Fort Detrick, MD.
C278 852.3
Identification of Novel Antimicrobial Peptides
to Be Used in Functional Foods. S. Doering, M. Thomas, J.E.
Grant, E.J. Lee. Univ. of Wisconsin-Stout.
853. ANTIBIOTIC RESISTANCE
Poster
Exhibit Halls A-D
C279 853.1
The Conserved DedA/Tvp38 Membrane
Protein Family Plays a Role in Antibiotic Resistance in
Pseudomonas aeruginosa M.R. Justice, J.S. Justice, W.T.
Doerrler. LSU, Baton Rouge.
C280 853.2
Genesis of Antibiotic Resistance XI: Critical
Appraisal of Disposal Method of National Prescription Drug
Take-Back Day. S. Kannan, L. Robles, N. Moody, M. Delgado,
V. Garcia, K. Moore, L. Echeverria, P. Ruiz, C. Martinez.
Southwest Texas Junior Col., Eagle Pass.
C281 853.3
Genesis of Antibiotic Resistance XII: Trifling
Role of SMARXT Disposal™ to Mitigate the Evolution of
Antibiotic Resistance. S. Kannan, P. Ambriz, O. Flores, P.
Fernandez, N. Carrales, E. Mata, A. Moreno, E. Herrera, J.
Hernandez. Southwest Texas Junior Col., Eagle Pass.
C282 853.4
Genesis of Antibiotic Resistance XIII: Critical
Appraisal of Incineration of Prescription Drug En Masse
from National Drug Take Back Day by United States Drug
Enforcement Administration – Department of Justice. S.
Kannan, J. Munoz, J. Luna, R. Rosales, J. Rodriguez, V. Ruiz,
M. Velez, L. Rodriguez, D. Chavez, P. Subburaj. Southwest
Texas Junior Col. and Sul Ross State Univ., Eagle Pass, TX.
C283 853.5
Genesis of Antibiotic Resistance (AR) XIV:
Inter-agency Anomaly in Data Sharing Debilitate the Mitigation
of AR Pandemic. S. Kannan, A. Villarreal, E. Valdez, R.
Villarreal-Moreno, J. Sanchez, G. Serna, K. Salazar, V.
Rodriguez, M. Padilla, C. Navejas. Southwest Texas Junior
Col., Eagle Pass.
C284 853.6
Genesis of Antibiotic Resistance (Ar) XV:
Genetic (Modification) Roulette Impairs Response to Antibiotics
– An Insidious AR Pandemic Phenomenon. S. Kannan, A.
Alvarez, G. Hernandez, M. Hernandez, J. Garza, T. Carrizales,
D. Carrizales, C. Crabtree, P. Subburaj. Southwest Texas
Junior Col. and Sul Ross State Univ., Eagle Pass.
C285 853.7
Genesis of Antibiotic Resistance XX: CDC
(Frieden’s) Report on AR and Executive Strategy to Mitigate AR
Pandemic Fail to Account Human Migration (Immigrants) and
Hardy-Weinberg -Castle Principle. S. Kannan, A. Alvarez, D.
Carrizales, T. Carrizales, S. Jouregui, N. Moody. Southwest
Texas Junior Col., Eagle Pass.
C286 853.8
Genesis of Antibiotic Resistance XVI: “Role
of Lax Regulations on Pharmaceuticals and Personal Care
Products in AR Pandemic” – Antibiotics, and Estradiol Are
Detected in Four Surface Water Sites of Edwards Aquifer
Authority, San Antonio, Texas. S. Kannan, D. Carrizales, T.
Carrizales, M. Hernandez, M. Moody. Southwest Texas Junior
Col. and Fort Duncan Reg. Med. Ctr., Eagle Pass, TX.
C287 853.9
Genesis of Antibiotic Resistance VIII: “Auto
Medication”, a Universal Practice That Contravenes HardyWeinberg-Castle Principle, Escalates as a Serious Risk Factor
in Mitigating AR Pandemic. S. Kannan, D. Carrizales, T.
Carrizales, A. Alvarez, S. Jouregui. Southwest Texas Junior
Col., Eagle Pass.
C288 853.10 Genesis of Antibiotic Resistance XIX: An
Alternative to Incineration of Prescription Drug Collection En
Masse. S. Kannan, L. Echeverria, J. Munoz, J. Luna, R.
Rosales, J. Rodriguez, V. Ruiz, M. Velez, L. Rodriguez, D.
Chavez, P. Subburaj, R. Villarreal-Moreno. Southwest Texas
Junior Col. and Sul Ross State Univ., Eagle Pass, TX.
C289 853.11 Genesis of Antibiotic Resistance (AR) XVII
Population Dynamics That Contravenes Hardy-WeinbergCastle Principle Augment AR Pandemic. N. Moody, D.
Carrizales, T. Carrizales, S. Kannan. Fort Duncan Reg. Med.
Ctr. and Southwest Texas Junior Col., Eagle Pass.
C290 853.12 Spatial Distribution of the Abundance
and Antibiotic Sensitivity of Staphlyococcus aureus in the
Hillsborough River. R. Seferian, A. Williams, B. Froeschke.
Univ. of Tampa.
C291 853.13 Progress towards Addressing Gram Negative
Bacterial Resistance. B.N. Koleva, K. Takrouri, H.D. Cooper,
A. Spaulding, P. Zucchi, D. Cleary, W. Tear, E.B. Hirsch, J.B.
Aggen, P.J. Beuning. Northeastern Univ.
854. DIET, OBESITY, NUTRITION AND
GUT MICROBIOME
Poster
Exhibit Halls A-D
C292 854.1
Lactobacillus plantarum Improves Metabolic
Outcomes and Alters the Colonic Immune State in Mice Fed a
High Fat Diet. D. Heeney, J. Barouei, Y-h. Hsieh, A. Martinic,
D. Mishchuk, D. Kieffer, C. Slupsky, R. Martin, M. Marco.
Univ. of California, Davis and USDA, Davis.
C293 854.2
Regulation of Adaptive Thermogenesis by
the Gut Microbiome. H.T. Nicholls, T.I. Krisko, K.B. LeClair,
A.S. Banks, D.E. Cohen. Brigham and Women’s Hosp. and
Harvard Med. Sch.
C294 854.3
Inclusion of Chicken Broth AAC1 as a Dietary
Supplement Modulates the Gut Microbiome: Results of NextGeneration DNA Sequencing. J. Hawkins, R. Norton, P.
Durham. Missouri State Univ. and Dynamic DNA Labs.
C295 854.4
Proximate Composition and Nutritional Profile
of Rhynchophorus palmarum W.O. Okunowo, A.M. Olagboye.
Univ. of Lagos, Nigeria.
855. GUT MICROBES, DRUGS AND TOXINS
Poster
Exhibit Halls A-D
C296 855.1
Characterization of Heterologously Expressed
Putative Cytolysins from Brachyspira hampsonii B.A. Keith,
J.C. Harding, J.E. Hill, M.E. Loewen. Univ. of Saskatchewan.
269
M
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BIOCHEMISTRYMONDAY
856. ALLOSTERIC CONTROL OF KINASE ACTIVITY
857. SIGNALING IN TIME AND SPACE
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C297 856.1
Mechanism and Interactions of Human Pyruvate
Dehydrogenase Complex with Its Kinase 1 E.L. Guevara, N.S.
Nemeria, L. Yang, F. Jordan. Rutgers Univ.-Newark.
C298 856.2
Prediction and Validation of New Polarity
Substrates Employing an aPKC Anchoring Motif. R. Constable,
N. McDonald, P. Saiu, E. Soriano, P. Knowles, A. Purkiss,
N. O’Reilly, P. Riou, P. Parker. The Francis Crick Inst.,
United Kingdom.
C299 856.3
Understanding the Phylogenetic Relationship
of Bacterial Arginine Kinases. K. Stock, M. Aryal, D. Fraga.
Col. of Wooster, OH.
C300 856.4
Evolution of Allostery in a Ser/Thr Kinase
Illuminating Novel Cancer Drug Targets. C. Zheng, A. Zorba,
C. Wilson, J. Villali, N. Kern, D. Kern. Brandeis Univ.
C301 856.5
Single Molecule Analysis of Allosteric
Interactions in Protein Kinase A. Y. Hao, J. England, S. Taylor,
R.A. Maillard. Georgetown Univ.
C302 856.6
PKA and Calcineurin Scaffolding on AKAP79: A
Small Angle Xray/Neutron Scattering Profile. J. Hall, J. Copps,
P. Zhang, A. Heck, W. Heller, D. Blumenthal, S. Taylor. UCSD,
The Scripps Res. Inst., Utrecht Inst. for Pharmaceut. Sci.,
Netherlands, Oak Ridge Natl. Labs. and Univ. of Utah.
C303 856.7
Substrate Selective Mechanisms in Protein
Kinases: Allostery between Nucleotide and Substrate in PKCα
R. Sommese, C. Swanson, S. Sivaramakrishnan. Univ. of
Minnesota, Minneapolis and Univ. of Michigan.
C304 856.8
Phosphorylation of PKA Regulatory Subunit
RIα by PKG: A Mechanism for “Desensitizing” the Type I PKA
Holoenzyme. K.J. Haushalter, D.E. Casteel, E. Stefan, S.S.
Taylor. UCSD and Univ. of Innsbruck.
C305 856.9
Activities of Dysregulated ALK2 Receptor
Kinases Provide Insight Into the Protein Structural-Functional
Basis of Fibrodysplasia Ossificans Progressiva. J.C. Groppe,
M.R. Tandang-Silvas, A. Pathi, J. Wu, G. Lu, V.Q. Le, A.L.
Culbert, K.A. Wharton, E.M. Shore, F.S. Kaplan. Texas A&M
Baylor Col. of Dent., Brown Univ. and Univ. of Pennsylvania.
C306 856.10 Protein Dynamics Defines Allostery in the
Conserved EPK Core. L.G. Ahuja, A.P. Kornev, C. McClendon,
G. Veglia, S.Taylor. UCSD and Univ. of Minnesota, Minneapolis.
C307 856.11 Covalent
Inhibition
of
ERK
Docking
Interactions. T.S. Kaoud, W.H. Johnson, A. Piserchio, N.D.
Ebelt, M. Warthaka, M. Cano, R. Sammons, Q. Wang, P. Ren,
R. Ghose, K.N. Dalby. Univ. of Texas at Austin, Fac. of Pharm.,
Minia Univ., Egypt and City Col. of New York.
C308 857.1
Three-Dimensional Quantification of the
Spatiotemporal Co-evolution of Vascular and Neuronal
Networks within Intact Eyes. J. Singh, D. Shepherd, G.
Seedorf, J. Brzezinski. Univ. of Colorado Denver and Univ. of
Colorado Sch. of Med., Aurora.
C309 857.2
An Optogenetic Toolkit for Spatial and
Temporal Control of the cAMP Dependent Protein Kinase. C.P.
OBanion, R. Hughes, M. Priestman, D. Lawrence. Univ. of
North Carolina Chapel Hill.
C310 857.3
Tracking Dynamics of Vascular Development in
Time and Space Using Sox18 Dimer Split-Fluorescent Protein
Biosensors. N. Giles, A. McCann, M. Moustaqil, J. Overman,
F. Fontaine, M. Francois, E. Sierecki, Y. Gambin. Sch. of
Med. Sci., Univ. of New South Wales and Univ. of Queensland.
C311 857.4
Super-Resolution Imaging of the HER Family
of Receptor Tyrosine Kinases. B. van Lengerich, E. Puchner,
B. Huang, N. Jura. UCSF and Univ. of Minnesota, Minneapolis.
C312 857.5
Investigating the Role of AKAP12 in Maintaining
G Protein-Coupled Receptor Responsiveness. D.J. Tóth, N.
Bojjireddy, T. Balla. NICHD, NIH.
C313 857.6
Integrin-Mediated
Signaling
Regulates
Efficiency of Lymphocyte Effector Functions. Y. Sykulev, N.
Anikeeva. Thomas Jefferson Univ.
858. DISEASES OF ORGANELLE MISFUNCTION
Poster
Exhibit Halls A-D
C314 858.1
Phenotype Analysis and Gene Expression
Profiling in a Yeast Model of Cystinosis. A.E. Walnofer, S.
Vitiello. Augustana Univ.
C315 858.2
SIRT3 Prevents Bleomycin-Induced Lung
Fibrosis in Mice by Blocking Mitochondrial DNA Damage and
ROS Synthesis. S. Bindu. Univ. of Chicago.
C316 858.3
Oxidatively Degraded Mitochondrial DNA Is
a Newly Identified DAMP Family Member in Astrocytes, and
Potential Trigger of Alzheimer’s Disease. A. Mathew. Albany
Med. Col.
859. FLUORESCENCE MICROSCOPY APPROACHES
TO UNDERSTAND APOPTOSIS
Poster
Exhibit Halls A-D
C317 859.1
Temporal Dynamics of Apoptotic Activity in
Jurkat Cells. S.K. Morris, R. Reif. Univ. of Mary Washington.
270
MONDAYBIOCHEMISTRY
860. INTRACELLULAR DYNAMICS
863. MITOCHONDRIAL TOXICITY
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C318 860.1
Characterizing the Functions of WHIMP as a
New WASP-Family Actin Nucleation Factor. S. Kabrawala, M.
Zimmer, K. Campellone. Univ. of Connecticut.
C319 860.2
Investigations of Functional Interactions
between Env7 and TOR Complex 1 in Saccharomyces
cerevisae J. Shaoulian, E. Gharakhanian. California State
Univ., Long Beach.
C320 860.3
ER-Associated SNAREs Are Involved in
Atlastin-Mediated ER Membrane Fusion. M. Lee, Y. Moon, S.Y.
Kim, Y. Jun. Gwangju Inst. of Sci. and Technol., South Korea.
861. MEMBRANE TRANSPORT
Poster
Exhibit Halls A-D
C321 861.1
YqjA Is a Putative Transporter Essential for
Alkaline pH Tolerance in Escherichia coli S. Kumar, W.T.
Doerrler. LSU, Baton Rouge.
C322 861.2
NHE1 Phosphorylation and Steady State
Intracellular pH. D. Hasle, M. Wallert, J.J. Provost. Univ. of
San Diego and Bemidji State Univ.
C323 861.3
NaPi2b Diffusion and Activity Could Be
Regulated by Membrane Fluidity in the Microvilli of the
Small Intestine. S.I. Al-Juboori, T. Lei, V. Hogg-Cornejo,
E. Sutherland, M. Levi, E. Dobrinskikh. Univ. of Colorado
Denver, Aurora.
C324 861.4
Identification
of
a
Mitochondrial
Oxodicarboxylate Carrier in the Oleaginous Yeast Yarrowia
lipolytica P.J. Trotter, K. Juco, S. McGreer, N. Orsi, P.N.
Pierson, N. Savage, L. Tamayo, J-M. Nicaud. Augustana Col.,
IL and BIMLip, INRA, Jouy-en-Josas, France.
C325 861.5
Mechanism of Transport of Ferric Enterobactin
through FepA in Gram Negative Bacteria A. Majumdar, V.
Trinh, K.J. Moore, C.R. Smallwood, S.M.C. Newton, P.E.
Klebba. Kansas State Univ. and Univ. of Oklahoma.
862. MITOCHONDRIAL DYNAMICS
Poster
Exhibit Halls A-D
C326 862.1
Sab-Mediated
Signaling
Regulates
Mitochondrial Fission. I. Paudel, J. Chambers. Florida
Intl. Univ.
C327 863.1
The Function of the Iron–Sulfur Cluster
Assembly Machinery Is Involved in Electron Transport Chain
Activity and Oxidative Stress in saccharomyces Cerevisiae M.
Gomez-Gallardo, L.A. Sanchez-Briones, A.L. Diaz-Perez,
A. Lopez-Alvarez, C. Cortes-Rojo, O. Aguilar-Mendez, A.
Saavedra-Molina, J. Campos-Garcia. Univ. Michoacana de
San Nicolas de Hidalgo, Mexico.
864. POSTTRANSLATIONAL MODIFICATIONS AND
THE MICROORGANISM RESPONSE
Poster
Exhibit Halls A-D
C331 864.1
Metabolite-Driven
Modifications:
Protein
Acylations Elucidate Substrate Metabolism in Syntrophic
Bacteria. H.H.T. Nguyen, P.H.N. Nguyen, R.P. Gunsalus, M.J.
McInerney, J.A. Loo, R.R. Ogorzalek Loo. UCLA and Univ.
of Oklahoma.
C332 864.2
Ate1-Mediated Posttranslational Arginylation
Is Essential for Stress Response Regulation and Mutagenesis
Suppression. A. Kumar, M.D. Birnbaum, W. Morgan, F. Zhang.
Univ. of Miami.
C333 864.3
Specificity
of
Protein
Arginine
Methyltransferases: How Does the Trypanosoma brucei PRMT7
Limit Its Activity to Monomethylation of Its Target Proteins? K.
Jain, R.A. Warmack, Y. Feng, E.W. Debler, P. Stavropoulos,
G. Blobel, S.G. Clarke. UCLA and The Rockefeller Univ.
C334 864.4
Transcriptome Profiling of Burkholderia
thailandensis Reveals That MftR Is a Master Regulator.
A. Gupta, G. Wang, M. Dassanayake, A. Grove. LSU,
Baton Rouge.
C335 864.5
Noncognate
Toxin-Antitoxin
Interactions:
Implications for Bacterial Persistence. A.L. Molinaro, D.A.
Daines. Old Dominion Univ.
C336 864.6
5hmC Distribution in Isolated Visceral Adipose
Tissue Nuclei. P. Yu, L. Ji, K. Lee, M. Yu, C. He, S. Ambati, R.
Schmitz, R. Meagher. Univ. of Georgia and Univ. of Chicago.
C337 864.7
Biochemical Characterization of the Substrate
Specificity of Two Unique Members of the Mammalian Protein
Arginine Methyltransferase Family, PRMT7 and PRM. T9 A.
Hadjikyriacou, Y. Feng, Y. Yang, M.T. Bedford, S.G. Clarke.
UCLA, City of Hope, Duarte and Univ. of Texas MD Anderson
Cancer Ctr.
C338 864.8
Using Anti-fungal Bacteria to Contest Snake
Fungal Disease. K. Malone. Tennessee Technol. Univ.
C339 864.9
Capacity of Chlorogenic Acid Isomers to
Modulate Oxidative and Inflammatory Responses in Caco2 Human Enterocyte-Like Cells. N. Liang, D. Kitts. Univ. of
British Columbia.
C340 864.10 Purification and Characterization of the
Drosophila melanogaster IKKβ/iKK&γ Complex. W.E. Rogers,
T. Huxford. San Diego State Univ. and UCSD.
271
M
O
N
BIOCHEMISTRYMONDAY
C341 864.11 Free Fatty Acid Activates MMP-1 and MMP3 through PPAR-γ Mitigation. W-M. Tsai, K-L. Tsai. Physical
Therapy, Tainan.
C342 864.12 Overcoming Challenges in the Diagnosis of
Schistosoma mansoni Infections Using Recombinant Protein
Technology. R.F.G. Queiroz, V. Silva-Moraes, N.B.F. Almeida,
D.A. Harn, P.M.Z. Coelho. FIOCRUZ,Belo Horizonte, Brazil
and Univ. of Georgia.
C343 864.13 Integrated Analysis of Posttranslational
Modification Proteomes Reveals Interactions and Cell Cycle
Regulatory Patterns In Toxoplasma gondii N.C. Silmon de
Monerri, R.R. Yakubu, L.M. Weiss, K. Kim. Albert Einstein
Col. of Med.
C344 864.14 AMPK Regulates Nuclear Trafficking of Nrf2
through Phosphorylation. M.S. Joo, W.D. Kim, S.G. Kim. Col.
of Pharm., Seoul Natl. Univ. and Boston, MA.
C345 864.15 Cell Polarity Kinase MST4 Cooperates with
cAMP-Dependent Kinase to Orchestrate Histamine-Stimulated
Acid Secretion in Gastric Parietal Cells. H. Jiang, W. Wang,
Y. Zhang, W.W. Yao, X. Ding, X. Liu, X. Yao. Univ. of Sci. and
Technol. of China, Hefei, Atlanta Clin. & Translational Sci. Inst.
and Beijing Univ. of Chinese Med.
C346 864.16 Autophagy Regulates the Early Secretory
Pathway through Interaction between ULK1 and Se. c23
S. Zhao, W. Gan, H.C. Chan, Yu. Sch. of Biomed. Sci., The
Chinese Univ. of Hong Kong.
C347 864.17 Isomerized Aspartate Residues in Rodent
Eye Lens Protein Act as a Marker of Biological Aging. R.A.
Warmack. UCLA.
C348 864.18 Role of Janus-Kinase 3 in Lung Inflammation.
J. Mishra, R.K. Verma, X. Yang, N. Kumar. Texas A&M Univ.,
Kingsville, VA Med. Ctr., Kansas City, MO, Univ. of MissouriKansas City and Texas A&M Univ. Hlth. Sci. Ctr.
C349 864.19 Nm23-Mediated
hnRNPA2/B1
to
Regulate Sp1 Expression Is Associated with Lung Cancer
Progression J-J. Hung. Inst. of Bioinformatics and Biosignal
Transduction, Tainan.
C350 864.20 Enzyme Catalyzed Expressed Protein Ligation.
S. Henager, N. Chu, Z. Chen, D. Bolduc, J. Wells, P. Cole.
Johns Hopkins Univ. and UCSF.
C351 864.21 β-Hydroxypyruvate Induced Side Chain
Modification of Human Serum Albumin and the Formation of
Advanced Glycation End-Products. W. Liu, J.A. Dain. Univ. of
Rhode Island.
C352 864.22 Investigation into the Role of N-Terminal
Acetylation of ESAT-6 in Pathogenesis of Mycobacterium
tuberculosis J.A. Aguilera, J. Sun. Univ. of Texas at El Paso.
C353 864.23 MIF SUMOylation in Regulation of Its Stability
and Activity during Breast Cancer Progression and Metastasis.
P. Sen, X-D. Zhang. Wayne State Univ.
C354 864.24 Proteome-Wide Structural Analysis of PTM
Hotspots Reveals Large Body of Putative Regulatory Elements
with Predicted Biological Function. H. Dewhurst, M. Torres.
Georgia Tech.
C355 864.25 Decreasing
O-GlcNAcylation
of
8-Oxoguanosine DNA Glycosylase (OGG1) in Cardiac
Myocytes Cultured in High Glucose Leads to Improvement of
DNA Repair and Mitochondrial Function. F. Cividini, A. Dai, B.
Scott, T. Diemer, J. Suarez, W. Dillmann. UCSD.
272
865. G PROTEINS AND PROTEIN KINASES
Poster
Exhibit Halls A-D
C356 865.1
Determinants of Gα12-Specific Binding
Common to AKAP-Lbc and p114rhoGEF. R.D. Garcia,
A.L. Towne, K.S. Cavagnini, T.E. Meigs. Univ. of North
Carolina Asheville.
C357 865.2
Novel Brain-Specific Isoforms of Regulator of
G Protein Signaling 6 K.E. Ahlers, A. Stewart, J. Yang, Z. Luo,
R.A. Fisher. Univ. of Iowa and Vanderbilt Univ.
C358 865.3
Overexpressed Gα13 Stimulates Serum
Response Factor Mediated Transcription Concurrent with
Relocalization to a Soluble Fraction. G.R. McDiarmid, A.C.
Tagliatela, T.E. Meigs. Univ. of North Carolina Asheville.
C359 865.4
GRK2 Constitutively Downregulates Delta
Opioid Receptor Activity in the Periphery. A.P. Doyle, R.
Gomez, M.A. Henry, N.A. Jeske. Univ. of Texas Hlth. Sci. Ctr.
at San Antonio.
C360 865.5
The Role of CaMKII in mGlu5 Signaling. C.R.
Marks, B.C. Shonesy, R.J. Colbran. Vanderbilt Univ.
C361 865.6
GPR161 and smAKAP Are Membrane-Bound
PKA-RI-Selective AKAP. T-W. Lu, R. Ilouz, E. Stefan, S. Taylor.
UCSD and Univ. of Innsbruck.
866.GTPASES
Poster
Exhibit Halls A-D
C362 866.1
Screening for Potential Inhibitors of the Proangiogenic GTPase TCL Using Split-Venus Reporter Proteins.
R. Florke, M. Hamann. Bemidji State Univ., MN.
C363 866.2
Bitter Taste Receptor T2R4 Mediated
Inactivation of Rac1 GTPase in Response to Quinine. C. Sidhu,
A. Jaggupilli, P. Chelikani, R.P. Bhullar. Univ. of Manitoba.
867. HORMONE RECEPTORS
Poster
Exhibit Halls A-D
C364 867.1
MicroRNA-124 Negatively Regulates Nuclear
Receptor Nu. r77 A. Farmer, J.A. Beard, A. Takwi, Y-m.
Wang, T. Chen. Univ. of Tennessee Hlth. Sci. Ctr. and St. Jude
Children’s Res. Hosp., Memphis.
C365 867.2
Immunofluorescence Localization of LigandInduced Internalization, Trafficking, and Signaling of eGFPTagged Guanylyl Cyclase/Natriuretic Peptide Receptor-A into
the Subcellular Compartments. I. Mani, S. Tripathi, R. Garg,
K.N. Pandey. Tulane Univ. Hlth. Sci. Ctr. and Sch. of Med.
C366 867.3
Local Aldosterone Synthesis in Skeletal
Muscle. J.A. Chadwick, S. Swagger, J. Lowe, J. RafaelFortney. The Ohio State Univ.
MONDAYBIOCHEMISTRY
C367 867.4
Biological
Funtions
for
Asn-Linked
Oligosaccharides in the Tethered Rec-Eel Luteinizing Hormone.
M. Byambaragchaa, K-S. Min, M-H. Kang. Hankyong Natl.
Univ. and Hoseo Univ., South Korea.
868. INTEGRATION AND ORGANIZATION OF
SIGNALING PATHWAYS
Poster
Exhibit Halls A-D
C368 868.1
Computational Analysis of the FLFP Motif in
the Cell Survival Mechanism Conferred by PKC&ΔVIII. B.M.
Brooks, K.A. Urbina, L. Parisot, S.E. Cole, A.C. Shor. Saint
Leo Univ.
C369 868.2
The Coordination of Notch and Integrin
Signaling by Resveratrol. B. LaFoya, A. Albig. Boise State Univ.
C370 868.3
The Impact of Redox Modification on the
Global Substrate Selection of PKA C Alpha. S. Patwardhan,
J. Delva, L. Beckett, J. Keyes, J.P. Neiswinger, H. Zhu, L.B.
Poole, R.H. Newman. North Carolina A&T State Univ., Wake
Forest Univ. and Johns Hopkins Univ.
C371 868.4
The Impact of Meprin A-Mediated Cleavage
on the Function of the Catalytic Subunit of Protein Kinase A
(PKA Cβ1) L. Beckett, S. Patwardhan, J. Delva, J. Jefferson,
M. Watson, E.M. Ongeri, R.H. Newman. North Carolina A&T
State Univ.
869.NEUROBIOLOGY
Poster
Exhibit Halls A-D
C372 869.1
A New Role for Thermosensors in
Drosophila melanogaster K.M. Marquez Gonzalez. Univ.
Metropolitana, PR.
C373 869.2
Histamine Mediates the Response to Light in
the Sensory Motor Integration of Gill Lateral Cell Cilia in the
Bivalve Mollusc, Crassostrea virginica D. Semple, K. Marrett,
M.A. Carroll, E.J. Catapane. Medgar Evers Col., NY.
C374 869.3
Beating of Gill Lateral Cell Cilia of Crassostrea
virginica Involves Neuronal Innervation and the Presence
of Gap Junctions. R. Buchanan, N. Dobey, D. Frank, E.J.
Catapane, M.A. Carroll. Medgar Evers Col., NY and Behavioral
Instruments, NJ.
C375 869.4
Modulation of Serotonin Synthesis, Reuptake,
and Degradation by 1,25-Dihydroxyvitamin D: Potential
Relevance for Neuropsychiatric Disorders. M.S. Sabir, C.M.
Dussik, I. Kaneko, G.K. Whitfield, M.R. Haussler, P.W.
Jurutka. Sch. of Math. and Nat. Sci., Arizona State Univ. and
Univ. of Arizona Col. of Med.
C376 869.5
The Lyme Disease Spirochete Borrelia
burgdorferi Induces Increased Expression of Multiple
Neuroinflammatory Factors in Human Microglial Cells In Vitro.
J.R. Greenmyer, R. Gaultney, B. McGregor, M. Burke, C.
Brissette, J. Watt. Univ. of North Dakota Sch. of Med. and
Hlth. Sci.
C377 869.6
Exchange Protein Directly Activated by cAMP
(EPAC) Regulates Neuronal Polarization through Rap1B. M.
Schmidt, P. Munoz Llancao, C. González-Billault1
Univ. of Groningen, Netherlands and Univ. of Chile.
C378 869.7
Novel Role of bHLH Protein Daughterless in
Synaptogenesis. E.L. Robinson, E.A. Waddell, M. D’Rozario,
D.R. Marenda. Drexel Univ.
C379 869.8
Spatiotemporal Dynamics and Regulation
of cAMP and PKA in Early Stage Hippocampal Neurons. K.
Gorshkov, S. Ramamurthy, S. Mehta, G.V. Ronnett, F. Zhou,
J. Zhang. Johns Hopkins Univ. Sch. of Med. and UCSD.
C380 869.9
Chicken Broth AAC1 as a Dietary Supplement
Inhibits Pain Transmission and Decreases Serum C-Reactive
Protein Levels in a Model of TMJ Disorder. P. Durham, J.
Hawkins. Missouri State Univ.
C381 869.10 A Novel Murine Experimental System for
Analyzing Differentiation of Oligodendrocyte Precursor
Cells Using Sox10-Venus Mice. N. Suzuki, K. Sekimoto, C.
Hayashi, Y. Mabuchi, E.G. Suto, T. Nakamura, C. Akazawa.
Tokyo Med. and Dent. Univ.
C382 869.11 Arachidonic Acid Cascade-Driven Neurotoxicity
in Hypobaric Hypoxia: An In Vivo Study. R. Choudhary, A.
Katyal. Univ. of Delhi.
C383 869.12 Neurodevelopmental Gene Expression of
Cannabinoid Receptor 2 (CB2R) in C57BL/6J and BTBRT+tf/j
and the CB2R Expression in Transgenic Knockout Mice (MUBx,
DAT, DATCI, SERT) E.K. Dennis. William Paterson Univ.
C384 869.13 Functions of Cx36, Life or Death? N.N.
Boonyasiti, A. Derib-Adugna, J. Dhillon, H. Hameedi, E.
Inthavong, A. Pardue, A. Schroeder. Olathe North H.S.,
Olathe, KS.
C385 869.14 Superresolution Microscopy Studies of Stx3
Clustering Mechanisms in Hippocampal Neurons. H. Thomson,
S. Lowenstein, J. Lochner. Lewis & Clark Col., OR.
870. NON-ALCOHOLIC FATTY LIVER DISEASE
Poster
M
O
N
Exhibit Halls A-D
C386 870.1
Hepatitis B Virus X Protein Induces Hepatic
Steatosis by Enhancing the Expression of Liver Fatty Acid
Binding Protein. X. Lin, Y-L. Wu, X-E. Peng, Y-B. Zhu, X-L.
Yan, W-N. Chen. Fujian Med. Univ., China.
C387 870.2
Dietary
Docosahexaenoic
Acid
Halts
Progression of Nonalcoholic Steatohepatitis, but Does Not
Promote Fibrosis Remission in Ldlr-/- mice. K.A. Lytle, C.
Wong, D. Jump. Oregon State Univ.
C388 870.3
Regulation of AMPK and Hepatic Metabolism
by Folic Acid Supplementation in Non-alcoholic Fatty Liver
Disease. V. Sid, N. Wu, L. Sarna, Y. Shang, J. House, Y.L.
Siow, K. O. Univ. of Manitoba, St. Boniface Hosp. Res. Ctr.
and Agr. and Agri-Food Canada, Winnipeg.
C389 870.4
Dual Activation of Bile Acid Receptors FXR
and TGR5 Plays a Protective Role in Non-alcoholic Fatty Liver
Disease and Atherosclerosis. K. Jadhav, Y. Xu, Y. Zhang.
Northeast Ohio Med. Univ.
C390 870.5
Palmitoleate Protection against PalmitateInduced Cholangiocyte Lipoapoptosis Is Sensitive to Pertussis
Toxin. S.K. Natarajan, M.A. Walker, M. Toews, J.L. Mott. Univ.
of Nebraska Med. Ctr.
273
BIOCHEMISTRYMONDAY
C391 870.6
Sphingosine-1-Phosphate
Signaling
in
Non-alcoholic Steatohepatitis. L.A. Cowart. Med. Univ. of
South Carolina.
C392 870.7
FTY720/fingolimod Reduces Steatosis in
a Murine Model of Non-alcoholic Fatty Liver Disease. T.D.
Rohrbach, A. Asgharpour, D. Avni, S.C. Cazanave, P.
Bedossa, A.J. Sanyal, S.D. Spiegel. Virginia Commonwealth
Univ. and Univ. Paris-Denis Diderot.
873. MEMBRANE PROTEIN SYNTHESIS, INSERTION
AND ASSEMBLY
871. HEPATIC LIPID SIGNALING: NAFLD
AND BEYOND
C400 873.1
Examining Interactions between Bacterioopsin
and Carotenoid Biosynthetic Proteins in the Halophilic
Archaeon Halobacterium salinarum A.M. Plesa, R.F. Peck.
Colby Col., ME.
Poster
Exhibit Halls A-D
C393 871.1
Cyclin D1 Regulates Adipose Triglyceride
Lipase to Influence Hepatic Lipid Droplet Metabolism and Cell
Proliferation. J. Ploeger, S. Kamarajugadda, D. Mashek, J.H.
Albrecht. Univ. of Minnesota.
872. LIPID SIGNALING
Poster
Exhibit Halls A-D
C394 872.1
Receptor for Advanced Glycation Endproducts
Modulates Leukotriene B4 Receptor 1 Signaling. T. Ichiki,
T. Koga, T. Okuno, K. Saeki, Y. Yamamoto, M. Sakaguchi,
T. Yokomizo. Juntendo Univ. Sch. of Med., Kanazawa Univ.
Grad. Sch. of Med. Sci., Okayama Univ. Grad. Sch. of Med.,
Dent. and Pharmaceut. Sci., Japan.
C395 872.2
Regulation of Store-Operated Calcium
Channels by Sphingosine 1 Phosphate. H.M. El-Shewy, M.H.
Lee, Y.K. Peterson, L.M. Luttrell. Med. Univ. of South Carolina
and Ralph H. Johnson VA Med. Ctr.
C396 872.3
Tracking Diacylglycerol Pools in Budding
Yeast. S. Ganesan, M.L. Sosa Ponce, V. Zaremberg. Univ. of
Calgary, Canada.
C397 872.4
Cysteinyl Leukotriene 2 Receptor Enhances
Angiogenesis, Vascular Permeability and Tumor Metastasis.
E. Duah, V. Kondeti, N. Al-Azzam, R. Adapala, P. Patil, C.
Thodeti, S. Paruchuri. Univ. of Akron and Northeast Ohio
Med. Univ.
C398 872.5
Biochemical Characterization of HDL/LDL-Like
Particles Secreted by Astrocytes. A. Nguyen, K. Cabrera.
Trinity Univ., TX.
C399 872.6
HPV16-E7 Oncoprotein Enhances CeramideMediated Lethal Mitophagy by Regulating the Rb/E2F5/Drp1
Signaling Axis. R. Thomas, N. Oleinik, B. Ogretmen. Med.
Univ. of South Carolina.
274
Poster
Exhibit Halls A-D
874. NON-ANIMAL GENETIC MODELS OF
LIPID METABOLISM
Poster
Exhibit Halls A-D
C401 874.1
Characterization of a Glycerophosphocholine
Acyltransferase from Saccharomyces cerevisiae S. Anaokar,
I. Lager, B. Glab, A. Banas, S. Stymne, J. Patton-Vogt.
Duquesne Univ., Swedish Univ. of Agr. Sci., Uppsala and Med.
Univ. of Gdansk, Poland.
C402 874.2
A Functional Relationship between Plb1Mediated Phosphatidylcholine Turnover and Sphingolipid
Homeostasis in Saccharomyces cerevisiae J. PattonVogt, S. Anaokar, J. Brant, B. Jonik, N. Nesbitt, M. Vera.
Duquesne Univ.
875. ORGANELLE LIPID BIOSYNTHESIS
Poster
Exhibit Halls A-D
C403 875.1
Homeostatic Regulation of Sphingolipid
Synthesis by the ORMDL Proteins: Molecular Mechanisms.
B. Wattenberg, D. Siow, M. Sunkara, A. Morris. Univ. of
Louisville and Univ. of Kentucky.
C404 875.2
Novel Interactions of Yeast Glycerol-3Phosphate Acyltransferases. B. Shabits, M. Tavassoli, V.
Zaremberg. Univ. of Calgary, Canada.
C405 875.3
Phosphorylation of Yeast Glycerol 3-Phosphate
Acyltransferase Gpt2 Regulates the Timing of TAG Synthesis
and Lipid Droplet Morphology. M. Tavassoli, B. Nagler, B.
Shabits, P. Sipila, K. Athenstaedt, V. Zaremberg. Univ. of
Calgary, Canada and Univ. Graz, Austria.
C406 875.4
Diihydroxyacetone Phosphate Acyltransferase
Is a Peripheral Membrane Protein. M. Chilije, E. Hoffarth,
G. Bertolesi, S. McFarlane, V. Zaremberg. Univ. of
Calgary, Canada.
MONDAYBIOCHEMISTRY
876. PROTEIN-LIPID INTERACTIONS AS
DETERMINANTS OF FUNCTION
Poster
C415 878.5
Unraveling
the
Structural
Basis
of
P-Glycoprotein Transport of Serotonin 5-HT1B/1D Receptor
Agonists: Eletriptan and Sumatriptan. D. Nguyen, L. Wilt, A.
Roberts. Univ. of Georgia.
C416 878.6
Identification of the Eletriptan Binding Site on
P-Glycoprotein Determined from Nuclear Magnetic Resonance
Spectroscopy. L. Wilt, A. Roberts. Univ. of Georgia.
C417 878.7
Heterodimerization
of
SLC30A10/ZnT10
and SLC30A3/ZnT3 Modulates ERK1/2 Activity. Y. Zhao,
R.G. Feresin, J.M. Falcon-Perez, G. Salazar. Florida State
Univ., Univ. of Arkansas for Med. Sci. and CIC bioGUNE,
CIBERehd, Spain.
C418 878.8
Modulatory Activation of an Invertebrate Kir
Channel by Protein Kinase C: Investigation of an Interaction
with PIP2 T.M. Larry, J.M. Butler, E.M. Leggett, N.M. Rockwell,
J.K. Bell, C.A. Villalba-Galea, L.M. Boland. Univ. of Richmond,
Univ. of San Diego and Virginia Commonwealth Univ.
C419 878.9
Structural Determination of the BBSome Core
Complex. T. Aoba. Brigham Young Univ.
C420 878.10 Transmembrane (TMEM)-163 Protein Is a
Novel Zinc Transporter. Q.W. Cantrell, J. Silva, C. Nguyen,
L.D. Hildebrand, T. Rivas, R. Shoemaker, A. Rojas, M.P.
Cuajungco. California State Univ., Fullerton.
Exhibit Halls A-D
879. VESICULAR TRAFFICKING
Poster
Exhibit Halls A-D
C407 876.1
Calcium Promotes Syntaxin 1 Mesoscale
Domain
Formation
through
Phosphatidylinositol
4,5-Bisphosphate. D. Milovanovic, A. Honigmann, G. van
den Bogaart, S.W. Hell, R. Jahn. Max Planck Inst. for Biophys.
Chem., Goettingen, Max Planck Inst. of Molec. Cell Biol. and
Genet., Dresden and Radboud Univ. Med. Ctr., Netherlands.
C408 876.2
The Structure and Function of COMM.
D1 Z.A. Rasmussen, K. Fitzpatrick, A. Choi. Univ. of
Alaska Anchorage.
877. STRUCTURAL BIOLOGY AND MECHANISMS OF
MEMBRANE LIPID ASSEMBLY
C409 877.1
Fourier Transform Infrared Spectroscopy
Detection of Lipid Ion-Pairing in the Staphylococcus aureus
Plasma Membrane. A.T. Duran, H. Marbach, B. Rasul, K.L.A.
Chan, R.D. Harvey. California State Univ., Fullerton and King’s
Col. London.
C410 877.2
Is the Site of Influenza Virus Assembly and
Budding Enriched with Cholesterol and Sphingolipids? M.L.
Kraft, A.N. Yeager, P.K. Weber, J. Zimmerberg. Univ. of Illinois
at Urbana-Champaign, Lawrence Livermore Natl. Lab. and
NICHD, NIH.
878. STRUCTURE AND FUNCTION OF TRANSPORT
PROTEINS AND CHANNELS
Poster
Poster
Exhibit Halls A-D
C421 879.1
Dysregulation of V-ATPase Function Impairs
Lysosomal Acidification in a Mouse Model of a Rare Lysosomal
Storage Disease, INCL. M.B. Bagh, S. Peng, G. Chandra, Z.
Zhang, A.B. Mukherjee. NICHD, NIH.
C422 879.2
Redefining Caveolae as Signalling Platforms:
Specificity of Interactions on Endocytic Caveolae in Response
to Stress. Y. Gambin, E. Sierecki, W. Jung, N. Ariotti, N. Giles,
M. Bastiani, R. parton. Univ. of New South Wales and Univ.
of Queensland.
880. LABORATORY COURSES
Exhibit Halls A-D
Poster
Exhibit Halls A-D
C411 878.1
Autism-Linked Mutations in the Human
Serotonin Transporter Induce Distinct Structural Changes That
May Account for the Altered Function of the Transporter. D.
Krout, L.K. Henry. Univ. of North Dakota.
C412 878.2
Structure-Function Analysis of MntP and
Other Manganese Exporter Proteins and Their Contribution to
Reactive Oxygen Species Survival. E. Martinez, R. Zeinert, J.
Schmitz, J. Draven, L. Waters. Univ. of Wisconsin-Oshkosh
and Univ. of Massachusetts Amherst
C413 878.3
Molecular Biology of Calcium Trigger Vesicle
Fusion in Situ. K. Cialowicz, R. Duncan, C. Rickman, E.
Brown, M. Euston. Heriot-Watt Univ., Edinburgh.
C414 878.4
Analysis of Large Conductance Ca2+-Activated
K+ (BK) Channels Dynamics in Living Cells. A. Miguelez, R.
Duncan, E. Brown. Heriot-Watt Univ., Edinburgh.
C423 880.1
Transforming an Undergraduate Biochemistry
Laboratory Courses: Do the Pros Outweigh the Cons? J.T.
Hazzard. Univ. of Arizona.
C424 880.2
A Ten Week, First-Semester Biochemistry
Lab Course Studying Bacterial Alkaline Phosphatase. D.S.
Witherow. Univ. of Tampa.
C425 880.3
An Inquiry-Based Exercise in Medicinal
Chemistry: Synthesis of a Molecular Library and Screening for
Potential Anti-malarial and Anti-inflammatory Compounds. D.J.
Hall, C.G. Martin, M. Welford, S. Debbert. Lawrence Univ.
C426 880.4
Measurement of Branched Chain Amino Acids
in Milks and Protein Supplements. K. Hubble, D. Swanson, K.
Keenan. Stockton Univ., NJ.
275
M
O
N
BIOCHEMISTRYMONDAY
C427 880.5
Pick a Color, Any Color: An Inquiry-Based
Laboratory Course Based on Fluorescent Protein Mutagenesis,
Expression, Purification and Characterization. D.A. Kraut.
Villanova Univ.
C428 880.6
Cloning and Characterizing a Beta-Glucanase
Gene from Oats: A Structure/Guided Inquiry-Based Molecular
Biology Laboratory. D.J. Martin. Saint Mary’s Univ., MN.
C429 880.7
A
Research-Based
Biochemistry
Lab
Focused on Gene Expression and RNA Degradation: Design,
Implementation and Outcomes. K.P. Callahan, S. Butler. St.
John Fisher Col. and Univ. of Rochester.
C430 880.8
A Redesigned Undergraduate Biochemistry
Lab. J.L. Mills, K. Hart, E. Thurnherr, S.F. O’Handley, H.J.
Bernstein, P.A. Craig. Sch. of Chem. and Material Sci.,
Rochester Inst. of Technol.
C431 880.9
Development of Course-Based Undergraduate
Research Experiences Using a Design-Based Approach.
S.M. Lo, D.L. Drane, S.L. Swarat, J.C. Mordacq. UCSD,
Northwestern Univ. and California State Univ., Fullerton.
C432 880.10 A Combination Course and Lab-Based
Approach to Teaching Research Skills to Undergraduates.
A.D. Parente, R.C. Brown, A.M. Danowitz, C.D. Jones, C.E.
Taylor. Mercyhurst Univ.
C433 880.11 A Guided Inquiry-Based Animal Cell Culture
Laboratory Course for Undergraduates. L.M. Carastro. Univ.
of Tampa.
881. ONLINE EDUCATION AND FLIPPING
THE CLASSROOM
Poster
Exhibit Halls A-D
C434 881.1
Engaging Medical Students in Amino Acid
Metabolism Using a Flipped Classroom Approach. T.A.
Clemons. Western Michigan Univ. Homer Stryker M.D. Sch.
of Med.
C435 881.2
Active Learning in a Flipped Classroom:
Implementation and Assessment. A.M. Barral, V.C. Ardi. Natl.
Univ., Costa Mesa and La Jolla.
882. PERSISTENCE IN SCIENCE OF STUDENTS OF
ALL BACKGROUNDS
Poster
Exhibit Halls A-D
C436 882.1
The Voelcker Biomedical Research Academy:
A Longitudinal and Multi-tiered Model for Preparing the Next
Generation of Biomedical Scientists. I. Chapa, J. Hensler,
L. McManus, A. Giuffrida. Univ. of Texas Hlth. Sci. Ctr. at
San Antonio.
C437 882.2
Teaching a Broad Non-science Major Audience
Using the Science of Food and Cooking. J.J. Provost, B. Kelly,
K. Colabroy, M. Wallert. Univ. of San Diego, Gustavus Adolphus
Col., MN, Muhlenberg Col., PA and Bemidji State Univ.
883. CAREER DEVELOPMENT PLANS AND
OPPORTUNITIES FOR UNDERGRADS, GRAD
STUDENTS, AND POSTDOCS
Poster
Exhibit Halls A-D
C438 883.1
Want to Get a Career Development Award?
Start Early. L-S. Huang, D.E. Carlson, W.C. Wang, J.D. Scott.
NHLBI, NIH.
C439 883.2
Analysis of NIEHS Postdoctoral Alumni Career
Outcomes. T.R.L. Collins, R. Gilliam, S. Peddada, H. Xu.
NIEHS, NIH, Durham, NC.
C440 883.3
The Balance of a PUI Career. What Is the
Tightrope You Walk? M. Benore, J.J. Provost, A. Aguanno,
Q. Vega. Univ. of Michigan-Dearborn, Univ. of San Diego,
Marymount Manhattan Col. and Montclair State Univ.
884. INTERDISCIPLINARY EDUCATION
CONCEPT INVENTORIES
Poster
Exhibit Halls A-D
C441 884.1
Bioenergetics Education: Art Meets Gentle
Science in Sickness and in Health. S. Iyer, R.R. Rao, S.
Faris, F. Heller, L. Hughes, R. Jamison, E.J. Lesnefsky, E.
Maurakis. VCU, Sci. Museum of Virginia and Hunter Holmes
McGuire VA Med. Ctr., Richmond.
276
MONDAYBIOCHEMISTRY/NUTRITION
885. MENTORING, NETWORKING AND SUCCESS
Poster
Exhibit Halls A-D
C448 886.3
Activatable COX-2 Probes in Optical Imaging
of Cancer. M.J. Uddin, B.C. Crews, K. Ghebreselasie, C.K.
Daniel, L.J. Marnett. Vanderbilt Univ. Sch. of Med.
887. CURRICULUM CHANGES IN PREMED EDUCATION
C442 885.1
Mentor-Mentee Interaction and Laboratory
Social Environment: Do They Matter in Doctoral Students’
Publication Productivity? M.A. Ynalvez, R. Ynalvez, E.
Ramirez. Texas A&M Intl. Univ.
C443 885.2
Getting the Word Out on Effective Ways to
Teach: The Promoting Active Learning & Mentoring (PALM)
Research Coordination Network. M.J. Wolyniak, K. Engen,
M. Peifer, A.J. Prunuske, E. Ruedi, S.M. Wick. HampdenSydney Col., VA, Amer. Soc. for Cell Biol., Bethesda, Amer.
Soc. of Plant Biologists, Bethesda, Univ. of North Carolina at
Chapel Hill, Univ. of Minnesota, Duluth and Genet. Soc. of
Amer., Bethesds and Univ. of Minnesota, St. Pau.
C444 885.3
Women in Scientific Discovery or Medicine
(WISDOM): Engaging K-12 and Undergraduate Students in
the Basic and Health Sciences. N.C. Woitowich, S. Pamarthy.
Rosalind Franklin Univ. of Med. and Sci.
C445 885.4
Building the Capacity of STEM Graduate
Students to Mentor in an Informal Afterschool Program. A.
Matias, P. Ortiz, G.F. Elphick, J. Duncan-Poitier, J. Lansing,
M. Groome, K. Breton. SUNY Empire State Col., Saratoga
Springs, SUNY Admin., Albany and New York Acad. of Sci.
886. EDUCATION AND/OR PROFESSIONAL
DEVELOPMENT IN BIOCHEMISTRY AND
MOLECULAR BIOLOGY
Poster
Exhibit Halls A-D
C446 886.1
Improving
Undergraduate
Biochemistry
Curriculum Using Threshold Concepts: An Analysis of Student
Understanding. S. Freese, K. James, J. Lewis, J. Loertscher,
V. Minderhout. Seattle Univ. and Univ. of South Florida.
C447 886.2
Effects of Helichrysum plicatum Extract
against Thallium (I) Sulphate-Induced Reproductive Damage
in Male Rats. A.D. Omur, B.A. Yildirim, S. Kucukler. Atatürk
Univ., Turkey.
Poster
Exhibit Halls A-D
C449 887.1
Organic
Chemistry
and
Biochemistry
Curriculum for the New MCAT. Y. Dobrydneva, L. Schwartz.
George Washington Sch. of Med. and Hlth. Sci.
C450 887.2
Creating an Outcomes-Based Biochemistry
Major from ASBMB and ACS Major Guidelines That Reflects
MCAT Needs. J.K. Bell, T.J. Dwyer, C.M. Loer, M.S. Lowery,
J.J. Provost. Univ. of San Diego.
888. MEDICAL AND DENTAL EDUCATION
Poster
Exhibit Halls A-D
C451 888.1
Implementation of the Molecular Basis of
Medicine Course at Unaizah College of Medicine, Qassim
University, Saudi Arabia from Boonshoft School of Medicine,
Wright State University: Analysis of Student Performance
in 2014-2015 L.J. Prochaska, F. Elmigdadi, H. Khader, K.
Mohany, W. Fadda, R. Aboukhalil, D.J. Organisciak, J.
Paietta, N.J. Reo, M.J. Miller, G.J. Onady, J. Donnelly, A.
Altwairgi, A. Alkadi, S. Aldamegh, D. Parmelee. Boonshoft
Sch. of Med., Wright State Univ. and Unaizah Col. of Med.,
Qassim Univ., Saudi Arabia.
C452 888.2
Collaborative Anatomy-Pathology Project:
Integrating Clinical Sciences Into the Pre-clinical Curriculum.
E. LaRose, T.R.T. Mitchell, H. Reisner, A. Siddiqui, B.
Newton, R. Terreberry, B. Brenseke, F. Anderson, N. Zaman.
Campbell Univ. Sch. of Osteo. Med.
Nutrition
889. OBESITY: MACRONUTRIENTS AND OBESITY
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D1
I889.1
Simulating the Influence of Changes
in Macronutrient Composition and Amounts in the American
Diet from 1971-2008 on Body Composition Changes and
Their Contribution to the Obesity Epidemic. R.T. Davidson, M.
Hippard. Logan Univ., MO.
D2
II889.2
Carbohydrate Intake Affects Weight
Loss Related Improvements in Glycemic Control: Results from
a Systematic Review and Regression Analysis. J. Li, C.S.
Wright, W.W. Campbell. Purdue Univ.
277
M
O
N
NUTRITIONMONDAY
D3
I889.3
Differences in Plasma Metabolites in
Insulin Resistant and Insulin Sensitive Obese Individuals during
a Hyperinsulinemic/Euglycemic Clamp. J.L. Casey, D.W. Van
Pelt, C. Burant, J. Horowitz, C. Evans. Univ. of Michigan Sch.
of Publ. Hlth. and Sch. of Kinesiol.
890. GLOBAL NUTRITION: LINEAR GROWTH AND
GROWTH FAILURE FROM CONCEPTION
TO ADULTHOOD
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D4
II890.1
How Well Do Nigerian Heath Staff
Interpret Weight Trajectory on Growth Charts in Children Under
6 Months? C.M. Wright, I. Ezeofor, A. Garcia. Sch. of Med.,
Univ. of Glasgow.
D5
I890.2
Validity of Photographic Imaging for
Assessing Standing Height of Preschoolers. J.J.S. Beintema,
N.W. Solomons, M.N. Orozco, R. García-Meza, R. Gwaltney,
H.B. Rolker, C.M. Doak. VU Univ., Amsterdam and CeSSIAM,
Guatemala City and Quetzalenango.
D6
II890.3 Comparison of Trunk-to-Leg Ratio
as Assessed by Photographic Imaging in Shorter and Taller
Preschool Children of the Western Highlands of Guatemala:
Implications Regarding the Biology of Stunting. J.J.S.
Beintema, N.W. Solomons, R. García-Meza, M.N. Orozco,
R. Gwaltney, C.M. Doak. VU Univ. Amsterdam and CeSSIAM,
Guatemala City and Quetzaltenango.
D7
I890.4
Inter- and Intra-Rater Concordance in
Estimating Height and Its Components Using Photographic
Images in Guatemalan Children from the Western Highlands.
M.N. Orozco, J.J.S. Beintema, R. García-Meza, R. Gwaltney,
H.B. Rolker, C.M. Doak, N.W. Solomons. CeSSIAM, Guatemala
City, VU Univ., Amsterdam and CeSSIAM Quetzaltenango.
D8
II890.5
Nutritional Status of Children under
Five Years and Associated Factors in Kalale District, Benin. D.
Taren, H. Alaofe, J. Burney, R. Naylor. Univ. of Arizona, UCSD
and Stanford.
D9
I890.6 How
Should
Undernutrition
Be
Diagnosed in Nigerian Hospitalised Infants Aged under Six
Months? C.M. Wright, I. Ezeofor, A. Garcia. Univ. of Glasgow.
D10 II890.7
The Influence of Maternal Nutrition on
Fetal Size Based on Ultrasound Measurements throughout
Pregnancy. P. Nguyen, M.F. Young, Y.O. Addo, H. Nguyen,
H. Pham, T.V. Truong, S.V. Truong, R. Martorell, U.
Ramakrishnan. IFPRI, Washington, DC, Thai Nguyen Univ. of
Med. and Pharm., Vietnam and Emory Univ.
D11
I890.8
Household Expenditures on Fruit and
Vegetables Are Associated with Significant Increases in zHFA
at Ages 5, 8 and 12 in Ethiopia, India, Peru and Vietnam. D.
Humphries, K.A. Dearden, B. Crookston, T. Woldehanna,
M.E. Penny, J. Behrman. Yale Univ., Micronutrient Initiative,
New Delhi, Brigham Young Univ., Addis Ababa Univ., Nutr. Inst.
of Invest., Peru and Univ. of Pennsylvania.
278
D12 II890.9
The Importance of Timing of Gestational
Weight Gain for Infant Birth Size in Vietnam. M.F. Young, P.H.
Nguyen, O.Y. Addo, H. Pham, T.V. Truong, S. Nguyen, R.
Martorell, U. Ramakrishnan. Emory Univ., Thai Nguyen Univ.
of Pharm. and Med., Vietnam and IFPRI,, Washington, DC.
D13 I890.10 Ultrasound
Measurements
during
the Third Trimester Predict Height and Stunting at 1 Year of
Age among Vietnamese Children. I. Gonzalez Casanova,
P. Nguyen, M.F. Young, N.D. Ford, H. Nguyen, H. Pham,
T.V. Truong, S.V. Truong, U. Ramakrishnan. Emory Univ.,
IFPRI, Washington, DC and Thai Nguyen Univ. of Med. and
Pharm., Vietnam.
D14 II890.11 Maternal
Education
and
Home
Environment Quality Protect Infants in Low Asset Families
from Poor Growth. M.M. Black, N. Tilton, K.M. Hurley, S.
Fernandez Rao, N. Balakrishna, K. Harding, G.A. Reinhart,
K.V. Radhakrishna, P. Ravinder, K. Madhavan Nair. Univ.
of Maryland Sch. of Med., Johns Hopkins Bloomberg Sch.
of Publ. Hlth., Natl. Inst. of Nutr.,Hyderabad, Micronutrient
Initiative, Ottawa and The Mathile Inst., Dayton.
D15 I890.12 Dietary Pattern with High Dairy Intake
Is Associated with Linear Growth in Peruvian Infants. J.E.
Arsenault, D. Lopez de Romaña, M. Penny, K.H. Brown.
Univ. of California, Davis, Inst. de Invest. Nutr., Lima and Bill &
Melinda Gates Fndn., Seattle.
D16 II890.13 Predictors of Improved HAZ in Rural
Egyptian Children. D.M. Winham. Iowa State Univ.
D17 I890.14 Cord Blood FGF21 and Leptin as
Candidate Biomarkers of Early Infant Linear Growth Velocity in
a Low-Income Country. S. Hack, E. Papp, J. Shi, M. Dimitris,
R. Bandsma, A. Al Mahmud, D. Roth. The Hosp. for Sick
Children, Toronto, icddr,b, Dhaka, Bangladesh and Univ.
of Toronto.
891. GLOBAL NUTRITION: IMPROVING THE DIETS
OF VULNERABLE POPULATIONS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D18 II891.1
Maternal Membership of Community
Groups Is Associated with Dietary Diversity among Children
6 to 12 Months of Age in Rural Ethiopia. Y. Kang, E. Seo,
J. Kim. Johns Hopkins Sch. of Publ. Hlth. and World Vision
Korea, Seoul.
D19 I891.2
A Novel Model of Pre-competitive
Public-Private Collaboration for Nutrition Research for
Vulnerable Populations. F.C. Vasta, M. Arabi, L.M. Neufeld.
Global Alliance for Improved Nutr., Washington, DC and
Geneva, Switzerland.
D20 II891.3 Predicted Effects of Current and
Potential Micronutrient Intervention Programs on Adequacy of
Folate and Vitamin B-12 Intake in a National Sample of Women
and Young Children in Cameroon. H. Luo, C.P. Stewart, K.H.
Brown, R. Engle-Stone. Univ. of California, Davis and Bill &
Melinda Gates Fndn.
MONDAYNUTRITION
D21 I891.4
Do Mass Media and Mobile Technology
Nutrition Education Campaigns Improve Infant and Young
Child Feeding Knowledge, Attitudes, and Practices in the
Developing World? A Systematic Review of the Evidence. M.
Graziose, Q. O’Brien, S. Downs, J. Fanzo. Teachers Col.
Columbia Univ., Mailman Sch. of Publ. Hlth., Columbia Univ.
Med. Ctr., Columbia Univ. and Sch. of Adv. Intl. Studies, Johns
Hopkins Univ.
D22 II891.5
Use of Dietary Scores for Diet Quality
Measurement: Relation with Nutritional Status of Women in
Northern Benin. J. Burney, H. Alaofe, R. Naylor, D. Taren.
UCSD, Univ. of Arizona and Stanford Woods Inst. for the Envrn.
D23 I891.6
The Maternal Domain: Social Support,
Decision-Making, Psychological Health and Child Feeding and
Anthropometry in Uganda. S. Ickes, M.P. Mandel, A. Roberts.
Univ. of Washington and Col. of William and Mary, VA.
D24 II891.7
Women’s Dietary Diversity in Rural
Bangladesh: Pathways through Women’s Empowerment. S.
Sinharoy, J. Waid, S. Gabrysch. Emory Univ., Helen Keller
Intl., Dhaka, Bangladesh and Ruprecht Karls Univ. Heidelberg.
D25 I891.8 Shifting Grounds: Perceptions of
Factors That Affect Agricultural and Nutrition Transitions in
Remote Hill Villages of Nepal. A.Z. Lei, U. Rai. Cornell Univ.
and Tribhuvan Univ., Nepal.
D26 II891.9
Consumption of Novel Thiamin-Fortified
Fish Sauce Improves the Thiamin Status of Rural Cambodian
Women of Childbearing Age and Their Children <5 Years. K.C.
Whitfield, C.D. Karakochuk, H. Kroeun, B. Chan, M. Borath,
L.D. Lynd, E.C.Y. Li-Chan, D.D. Kitts, T.J. Green. Univ. of
British Columbia, Helen Keller Intl. - Cambodia, Ministry of
Planning, Phnom Penh and South Australian Hlth. and Med.
Res. Inst., Adelaide.
D27 I891.10 “Molds Attack Rice - but We Don’t
Know What to Do”. A Qualitative Study of Farming Families’
Perceptions of Food Safety in Banke, Nepal. J.Y. Andrews
Chavez, S. Ghosh, B.L. Rogers, G. Shively, K. Baral, P.
Webb. Tufts Univ., Boston, Purdue Univ. and Patan Acad. of
Hlth. Sci., Kathmandu.
D28 II891.11Developing
Food-Based
Recommendations to Complement Distribution of a MeatBased Fortified Food Product for School-Aged Children from
Rural Quetzaltenango, Guatemala Using the Optifood Linear
Programming Tool. M. Vossenaar, M.L. Escobar, M.J.L.
Bonorden, N.W. Solomons. CeSSIAM, Guatemala City and
Hormel Foods Corp., Austin, MN.
D29 I891.12
Consumption of Native and Traditional
Crops in Bolivia Varies along an Ecoregional Gradient. A.
Keleman Saxena, X. Cadima Fuentes, D. Illanes Velarde,
D. Humphries. Sch. of Epidemiol. and Publ. Hlth., Yale Univ.,
Fndn. PROINPA, Bolivia and Univ. Mayor de San Simon, Bolivia.
D30 II891.13 Impact of a Comprehensive Nutrition
Program on Infant and Young Child Feeding Practices among
Children Aged 6 to <24 Months in Rural Malawi. K.M. Hurley,
Y. Kang, A. Bou Monclus, J. Ruel-Bergeron, R. Oemcke,
L.S.F. Wu, M. Mitra, J. Phuka, P. Christian. Johns Hopkins
Bloomberg Sch. of Publ. Hlth. and Col. of Med., Univ. of Malawi.
D31 I891.14 Dietary Intake and Nutritional Status
in Infants from the Urban Slums of Mumbai, India. S.
Venkatramanan, J.D. Haas, J.L. Finkelstein, A. Salvi, A.
Thorat, S.L. Huey, S.A. Udipi, P. Ghugre, A.V. Kurpad, S.
Mehta. Cornell Univ., SNDT Univ., Mumbai and St. Johns Res.
Inst., Bengaluru India.
D32 II891.15 Understanding Intrahousehold Factors
Prior to Infant and Young Child Feeding Programming with
Micronutrient Powder in Northern Nigeria. S.R. Kodish, P.
Mathema, A. Imohe, T. Osunkentan, C.L. Ejembi. Johns
Hopkins Bloomberg Sch. of Publ. Hlth., UNICEF Nigeria and
Ahmadu Bello Univ., Nigeria.
892. GLOBAL NUTRITION: MEASURING AND
IMPROVING MICRONUTRIENT STATUS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D33 I892.1
Perceived Iron Content in Drinking
Water Associated with Anemia among Women with Iron-Poor
Diets in Rural Bangladesh. A. Wendt, J. Waid, S. Gabrysch.
Univ. of Heidelberg and Helen Keller Intl., Bangladesh.
D34 II892.2
Iodine Status Has Changed between
2001 and 2012 in U.S. Adults. K.W. Lee, M.S. Cho, D. Shin,
W.O. Song. Michigan State Univ., Ewha Womans Univ.,
South Korea.
D35 I892.3
Oral Contraceptive Use Is Associated
with Increased Serum 25-Hydroxyvitamin D and Decreased
Serum Parathyroid Hormone but Not with Bone Mass Status
in Young Adult Uruguayan Women. R. Cornes, A. Peña, C.M.
Donangelo. Sch. of Nutr., Univ. of the Republic, Uruguay.
D36 II892.4 Use of Modified Relative DoseResponse to Examine Sensitivity and Specificity of Retinol
Binding Protein as an Indicator of Vitamin A Deficiency among
Nepali Children 6-23 Months of Age. R.D. Whitehead; Jr., C.G.
Perrine, R.C. Flores-Ayala, S.A. Tanumihardjo, P. Dahal, S.
Mebrahtu, G.R. Subedi, M.E. Jefferds. Ctrs. for Dis. Control
and Prevent., Univ. of Wisconsin-Madison, UNICEF, Lalitpur,
Nepal and MoHP, Kathmandu, Nepal.
D37 I892.5
Risk of Neural Tube Defects Based
on Red Blood Cell Folate among Women in the Dominican
Republic. R.D. Whitehead; Jr., C.G. Perrine, A.T. Paulino,
S.S. Torbio, M.E. Jefferds. Ctrs. for Dis. Control and Prevent.
and MoHP, Santo Domingo.
D38 II892.6
Comparison of Selected Nutrients in
Raw, Whole Egg from USDA Data Releases (1976 – 2010) M.
Somanchi, J. Exler, P.R. Pehrsson. USDA, Beltsville, MD.
D39 I892.7
Effect of Antioxidants on Vitamins A, E
and Carotenoid Stability in Dried Blood Spots. F.X. Arredondo,
N.E. Craft. Craft Technols. Inc., Wilson, NC.
D40 II892.8
Vitamin D Status of Husbands of
Pregnant Women in Dhaka, Bangladesh. L. Ruiter, J. Shi, E.
Papp, A.A. Mahmud, A. Gernand, D. Roth. Univ. of Toronto,
Hosp. for Sick Children, Toronto, icddr, Dhaka, Bangladesh
and Penn State.
D41 I892.9
Assessment of Micronutrient Status in
Pregnant Malawian Women before and after Treatment for
Moderate Malnutrition. C.M. Glosz, S. Reaves, M. Manary, P.
Papathakis. Cal Poly Univ., San Luis Obispo and Washington
Univ. Sch. of Med.
279
M
O
N
NUTRITIONMONDAY
D42 II892.10
Anemia, Iron and Vitamin A Deficits Are
Still Public Health Issues among Women and Young Children
in Northern Benin. H. Alaofe, J. Burney, R. Naylor, D. Taren.
Univ. of Arizona, UCSD and Stanford Univ.
D43 I892.11 Plasma Proteome Associated with
Hepcidin and Iron Status in 6-8 Year Old Children of Rural
Nepal. S. Baker, M.A. Arguello, K.J. Schulze, S.E. Lee, R.
Cole, L. Wu, B. Nonyane, J. Yager, J. Groopman, P. Christian,
K. West. Johns Hopkins Bloomberg Sch. of Publ. Hlth.
D44 II892.12 Addressing Anemia in Women and
Children in Rural Communities of Cambodia and Kenya:
Experiences from an Integrated Program. B.A. Aidam, A.
Edward, A.C. Paden, R.Y.S. Wong, J. Chege. World Vision
Intl., Washington, DC and Bloomberg Sch. of Publ. Hlth., Johns
Hopkins Univ.
D45 I892.13
Determining an Optimal Plasma Folate
Concentration Associated with the Prevention of Neural Tube
Defects. A. Sekkarie, R.J. Berry, Y.P. Qi, K. Crider. Ctrs. for
Dis. Control and Prevent. and Carter Consulting Inc., Atlanta.
D46 II892.14
Vitamin D Insufficiency among Lactating
Women in Southern Ethiopia. M. Girma, B. Tilahun, B.J.
Stoecker. Oklahoma State Univ., Hawassa Univ. and Hawassa
Univ. Col. of Med. & Hlth. Sci., Ethiopia.
D47 I892.15
Use of Zn Kinetics in the Design of Zn
Supplementation Studies. M.E. Wastney, J. King. Metabolic
Modeling, West Lafayette, IN and Children’s Hosp. Oakland
Res. Inst., CA.
D48 II892.16 Reducing Micronutrient Deficiencies in
a Decentralized Setting: Lessons in Food Fortification from the
Philippines. C.C.S. Acuin, L. Perlas, C. Duante, M. Serafico,
A.J. Ducay, M. Capanzana. Food and Nutr. Res. Inst.,
Taguig, Philippines.
D49 I892.17
Effectiveness and Tolerability of Various
Ferrous Salts in Correcting Mild to Moderate Iron Deficiency
Anemia in Indonesian Women. S. Ashmead, J. Hartle.
Albion, UT.
D50 II892.18 Socio-economic Variables Associated
with Anaemia during Pregnancy in Owerri Imo State, Nigeria.
O.C. Afam-Anene, A.C. Uwaegbute. Imo State Univ. and
Michael Okpara Univ. of Agr., Nigeria.
D51 I892.19 The Cornell NutriPhone: Enabling
Precision Nutrition. S. Mehta, D.C. Erickson. Cornell Univ. and
Sch. of Mech. and Aerosp. Engin., Cornell Univ.
893. PULSES, NUTRITION AND HEALTH
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D52 II893.1
Sarcopenic Obesity in Women with
Polycystic Ovary Syndrome: Effect of a Pulse-Based Diet
and Exercise Intervention. L.E. McBreairty, G.A. Zello, J.J.
Gordon, D.R. Chizen, P.D. Chilibeck. Univ. of Saskatchewan.
D53 I893.2
Development of Low Glycemic Index
(GI) Foods by Incorporating Pulse Ingredients Into CerealBased Products: Use of In Vitro Screening and In Vivo GI
Determination. N. Fujiwara, C. Hall, A.L. Jenkins. No. Crops
Inst., Fargo, North Dakota State Univ. and Glycemic Index
Labs., Toronto.
280
D54 II893.3
Carbohydrate Fractions in Chickpeas,
Lentils and Dry Peas. D.B. Haytowitz. USDA, Beltsville, MD.
D55 I893.4
Acute Effects of Lentil Fractions on
Satiety and Glycemic Responses before and after a Meal in
Healthy Young Men. H. Fabek, A. Rajadurai, M.U. Arshad,
C.E. Smith, B.G. Bailo, R. Kubant, G.H. Anderson. Univ.
of Toronto.
D56 II893.5
The Role of Caregiver Communication
in Children’s Liking and Consumption of Lentils. A.J. Roe, J.N.
Davis, S.L. Johnson, S.A. Ramsay. Univ. of Idaho and Univ.
of Colorado Anschutz Med. Campus.
D57 I893.6 Common
Bean
and
Chickpea
Supplemented Diets Beneficially Enhance the Colonic
Microenvironment and Reduce Colitis-Associated Inflammation.
K.A. Power, J.M. Monk, D. Lepp, L.E. Robinson, W. Wu, C.
Carey, D. Graf, A. Hussain, L. McGillis. Agr. and Agri-Food
Canada, Guelph and Univ. of Guelph.
D58 II893.7
Fortification of Yogurt with Chickpea
Flour Decreases Fermentation Time and Enhances Overall
Quality of Yogurt. X. Chen, R. Ramanathan, K. Bhargava.
Univ. of Central Oklahoma and Oklahoma State Univ.
D59 I893.8
Impact of Processing on the Protein
Quality of a Pinto Bean/Buckwheat Blend, as Determined
by In Vitro and In Vivo Methodologies. M.G. Nosworthy, A.
Franczyk, J. Neufeld, J.D. House. Univ. of Manitoba.
D60 II893.9
The Effect of Consuming a LowGlycemic Index Lentil-Based Sports Nutrition Bar on Recovery
after a Soccer Match. M. Kaviani, P. Chilibeck, S. Gall, J.
Jochim, G. Zello. Col. of Kinesiol. and Col. of Pharm. and
Nutr., Univ. of Saskatchewan.
D61 I893.10 Consumption of Roasted Chick Peas
Results in Increased Excretion of Oral Bacteria in Feces. V. Mai,
S.G. Waugh, D.J. Simpson, F.R. Hadjimiry, M. Ukhanova.
Univ. of FLorida.
D62 II893.11 Chickpea Bread, a Low Glycemic
Index Bread Alternative. S. Blanco Mejia, C. Ireland, C.W.C.
Kendall, J.L. Sievenpiper, T.M.S. Wolever, V.V.V. Vuksan, P.B.
Pencharz, D.J.A. Jenkins. St. Michael’s Hosp., Toronto, Univ.
of Toronto Fac. of Med., Univ. of Saskatchewan Col. of Pharm.
and Nutr. and Sick Kids Hosp.,Toronto.
D63 I893.12 Predication of Glycemic Response of
Extruded Pulse Products Using n Vitro Analysis. S. Joseph
Thandapilly, R. Mollard, J. Curran, D.R. Bouchard, P.
Jones, N. Ames. Agr. and Agri-Food Canada,Winnipeg,
Univ. of Manitoba, Pulse Canada,Winnipeg and Univ. of New
Brunswick, Canada.
D64 II893.13 The Sensory Characteristics of Whole
and Puréed Navy Beans: Effect of Processing. B.L. Luhovyy,
A. Martynenko, T. Chiu, K. Mather, R. Boachie, A. Hamilton,
Y. Chen. Mount Saint Vincent Univ. and Dalhousie Univ.,
NS, Canada.
D65 I893.14 Satiety Effects of Lentils in a Calorie
Matched Fruit Smoothie. J. Erickson, A. Rendahl, J. Slavin.
Univ. of Minnesota, St. Paul.
MONDAYNUTRITION
894. FACTORS INFLUENCING LONG-TERM
ECONOMIC/ENVIRONMENTAL SUSTAINABILITY
OF THE FOOD SUPPLY
895. NUTRITION EDUCATION: DEVELOPING
HEALTHY EATING AND PHYSICAL ACTIVITY
BEHAVIORS ACROSS THE LIFESPAN
Poster
Poster
Exhibit Halls A-D
Science RIS)
1:45 pm–2:45 pm (II)
Exhibit Halls A-D
D66 II894.1
Characterizing Early Adolescent Food
Waste Using the Mobile Food Record. J.C. Banna, C. Panizza,
C. Boushey, E. Delp, E. Lim. Univ. of Hawaii at Manoa, Curtin
Univ., Australia, Univ. of Hawaii Cancer Ctr. and Purdue Univ.
D67 I894.2 Examination of Sociodemographic
Correlates of Plate Waste in Early Adolescent Girls. C.
Panizza, C. Boushey, E. Delp, E. Lim, J.C. Banna. Curtin
Univ., Australia, Univ. of Hawaii Cancer Ctr., Purdue Univ. and
Univ. of Hawaii at Manoa.
D68 II894.3
Eating Away at Climate Change –
Substituting Beans for Beef to Help Meet U.S Climate Targets.
H. Harwatt, J. Sabate, G. Eshel, S. Soret, W. Ripple. Loma
Linda Univ., Bard Col., NY and Oregon State Univ.
D69 I894.4
Examining Local Fish Consumption in
the Globalized Lake Victoria Fishery. K.J. Fiorella, K. Seto,
E. Gavenus, E.M. Milner, D.O. Omollo, B. Mattah, L.C.H.
Fernald, J. Brashares. Cornell Univ., Univ. of California,
Berkeley and Organic Hlth. Response, Kenya.
D70 II894.5
Sustainability of Soy Protein from Life
Cycle Assessment. M. Braun, I. Muñoz, J.H. Schmidt, M.
Thrane. DuPont Nutr. & Hlth., St. Louis, 2.-0 LCA Consultants,
Aalborg and DuPont Nutr. & Hlth., Brabrand, Denmark.
D71 I894.6
Healthy and Sustainable Diets: The
Development and Application of a Policy Analysis Framework.
S. Downs, A. Payne, J. Fanzo. Columbia Univ., Amplify Urban
Planning and Develop., NYC and Sch. of Adv. Intl. Studies,
Johns Hopkins Univ.
D72 II894.7
Perspectives of Public, Private and Civil
Sectors in the Development and Maintenance of a Local Food
System. D. Cuy Castellanos, J. Christaldi, J. Jones. Univ. of
Dayton, West Chester Univ. and Rutgers Univ.
D73 I894.8
The Future of Meat: Exploring the
Nutritional Qualities and Environmental Impacts of Meat
Replacements. M.A. Mejia, H. Harwatt, K. Jaceldo-Siegl, S.
Soret, J. Sabate. Andrews Univ. and Sch. of Publ. Hlth., Loma
Linda Univ.
1:45 pm–2:45 pm (II)
D74 II895.1
Peer Mentoring to Prevent Obesity in
First Year College Students: Get Fruved. S. Colby, W. Zhou,
W. Yan, S. Dahlman, M. Olfert, M. Barr, K. Kattelmann, K.
Leischner, A. Mathews, K. Shelnutt, M. Vilaro, O. Brown,
T. Kidd, T. Horacek, A. White. Univ. of Tennessee, Knoxville,
West Virginia Univ., South Dakota State Univ., Univ. of Florida,
Auburn Univ., Kansas State Univ., Syracuse Univ. and Univ.
of Maine.
D75 I895.2
“iRun”! An Evaluation of the Addition
of Nutrition Education and a Fitness Log to an Existing AfterSchool Fitness Program. J. Bell, M. Spence, K. Aaron, S.
Colby, K. Kavanagh. Univ. of Tennessee, Knoxville and East
Tennessee Children’s Hosp.
D76 II895.3
An Online Study of Undergraduates’
Knowledge, Awareness, and Attitudes of Preconception Care.
K.J. Crusenberry, S.E. Colby, M.L. Spence, L.T. Murphy, K.F.
Kavanagh. Univ. of Tennessee, Knoxville.
D77 I895.4
Flowers, Hearts, and Stars, Oh My!:
Fruit and Vegetable Intake of Preschoolers. K.L. Clay, S. Colby,
K. Kavanagh, M. Spence. Univ. of Tennessee, Knoxville.
D78 II895.5
What Is a Snack, Why Do We Snack,
and How Can We Choose Better Snacks? The Definitions
of Snacking, Motivations to Snack, Contributions to Dietary
Intake, and Recommendations for Improvement. J. Hess, S.
Jonnalagadda, J. Slavin. Univ. of Minnesota, St. Paul and
Kerry, Beloit, WI.
D79 I895.6
Developmental and Gender Differences
in Risk Taking in Response to Caffeine. A. Graczyk, A. Ziegler,
A. Atkins, H. Carrasco, J. Temple. Univ. at Buffalo, SUNY.
D80 II895.7 Physical Activity Patterns versus
Sedentary Behaviours, Awareness of Recommendations and
Overweight in Physically Active Male Brazilian Adolescents
– The Fit Food Study. R.H.V. Machado, I. Iglesia, J.S. Silva,
A.B. Neto, C.A. Hartwick, A. Pires, M. Fisberg, L. Moreno.
Sabara Children’s Hosp./José Luiz Egydio Setubal Fndn., São
Paulo, Univ. of Zaragoza, Spain, Danone Res. and Danone
Inst. Intl., Paris and Fed. Univ. of São Paulo.
D81 I895.8
The Nutrient-Density of Snacks: A
Comparison of Nutrient Profiles of Popular Snack Foods Using
the Nutrient Rich Foods Index. J. Hess, G. Rao, J. Slavin.
Univ. of Minnesota, st. Paul and NorthShore Univ. Hlth. Syst./
Univ. of Chicago,, Glenview.
D82 II895.9 Comparing Dietary Strategies to
Increase Vegetable Consumption: Encouraging Tomato
Products versus Raw Vegetable Consumption. S. Rahman,
E. Park, K. Reimers, B.M. Burton-Freeman. Illinois Inst. of
Technol. and ConAgra Foods, Omaha.
281
M
O
N
NUTRITIONMONDAY
D83 I895.10 Participants in the Shaping Healthy
Choices Program Increased the Intensity of Physical Activity.
D.S. Fetter, R.E. Scherr, J.D. Linnell, M. Dharmar, S.E.
Schaefer, K.M. Brian, S. Zidenberg-Cherr. Univ. of California,
Davis, Sch. of Nursing, Davis Hlth. Syst., Sacramento, Agr. and
Nat. Resources, Davis and Coop. Ext., Auburn, CA.
D84 II895.11 Demographic
Factors
Influencing
Obesity Risk Reduction Behaviors among Chinese Americans.
D. Liou, K. Bauer, Y. Bai. Montclair State Univ.
D85 I895.12
Impact of Military Dining Facility Serving
Modifications on the Nutritional Intake of Special Operations
Personnel. A.S. Bukhari, A.P. Crombie, S.M. McGraw, C.M.
Champagne, A. Ray, S.J. Montain, A.J. Young. U.S. Army
Res. Inst. of Envrn. Med., Natick, MA, U.S. Military-Baylor
Univ. Grad. Prog. in Nutr., Fort Sam Houston and Pennington
Biomed. Res. Ctr., Baton Rouge.
D86 II895.13 Observed Differences in Child Picky
Eating Behaviors between the Child’s Home and Center- or
Home-Based Childcare. V. Luchini, S-Y. Lee, S. Donovan.
Univ. of Illinois at Urbana-Champaign.
896. NUTRITION EDUCATION: EVIDENCE-BASED
NUTRITION EDUCATION: DEVELOPMENT,
TESTING, AND EVALUATION
Poster
Science RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D87 I896.1
Implementation of a Nutrition?Education
Program Designed to Improve the Diets of Low Income
Underserved Populations. M.P. Corcoran, P. Keighley.
Merrimack Col., MA.
D88 II896.2
Comparing the Effectiveness of Two
Nutrition Intervention Programs on Adolescents’ Intrinsic
Motivation and Perceived Competence to Cook Using the
Adolescent Motivation to Cook Questionnaire. D. Miketinas,
M. Cater, B. Craft, H. Roy, A. Bailey, G. Tuuri. Sch. of Nutr.
and Food Sci., LSU and LSU Agr. Ctr.
D89 I896.3
Physician Nutrition Education Program:
Adding Value to Patient Care by Increasing Physician Expertise
in Nutrition. K.K. Hicks, M.K. Irion, P.S. Murano. Texas A&M
Univ., College Station and Bryan, TX.
D90 II896.4 Wave
Virtual
World
Learning
Environment for Childhood Obesity Prevention: High School
Soccer Players’ Perspectives – A Pilot Study. S.S. Wong,
Y. Meng, J. Bruntmyer, J. Cui, M.M. Manore, J. Dorbolo.
Oregon State Univ.
D91 I896.5
Promotion of Healthy Food Choices
in School Children through Nutrition Education. V. Davar.
Kurukshetra Univ., India.
D92 II896.6
Culinary Skills Intervention: Immediate
Impacts on Knowledge, Attitudes and Self-Efficacy in
Adolescent Youth. A.R. Oakley, S.M. Nickols-Richardson.
Univ. of Illinois at Urbana-Champaign.
282
D93 I896.7
Perceptions,
Beliefs,
and
Implementation of the Dietary Guidelines for Americans
Consumer Messages by Low-Income Parents. M. Chea, A.R.
Mobley. Univ. of Connecticut.
D94 II896.8 Nutrition Education Intervention in
Kindergarteners: Effects on Knowledge and Behavior. L.
Hoolihan, A. Larsen, Y. Liao, G.F. Dunton. Dairy Council
of California, Irvine, Hermosa Beach and CA, Univ. of
So. California.
D95 I896.9
Validation of Two Brief Questionnaires
Designed to Assess Fruit and Vegetable Intake among 3rd5th Grade SNAP-Ed Participants. Y. Zhang, G. Hurtado, M.
Reicks. Univ. of Minnesota-Twin Cities.
D96 II896.10
Attracting Attention: Parent Perceptions
of Coverlines on Homestyles Guides. J.T. Martin-Biggers,
C. Delaney, G. Povis-Alleman, N. Hongu, J. Worobey, C.
Byrd-Bredbenner. Rutgers Univ., New Brunswick and Univ.
of Arizona.
D97 I896.11 Coordination of Classroom Nutrition
Education with School Nutrition Services Programs in California
Schools. A.M. Jones, M. Briggs, J. BoarerPitchford, S.
Zidenberg-Cherr. Univ. of California, Davis, California Dept .
of Educ., Sacramento and Univ. of California ANR, Davis.
D98 II896.12
Whole Grain Willingness Questionnaire:
Examining College Students’ Attitudes toward Consuming
Whole Grains through Exploratory Factor Analysis. B.
Craft, M. Cater, A. Bailey, G. Tuuri. LSU and LSU. Agr. Ctr.,
Baton Rouge.
D99 I896.13 Validation
of
General
Nutrition
Knowledge Questionnaire for Adults in Uganda. R. Bukenya,
A. Ahmed, K.M. Chapman- Novakofski, J. Muyonga, J.
Andrade. Univ. of Illinois Urbana-Champaign and Makerere
Univ., Uganda.
D100 II896.14Parent
and
Adolescent
Child
Perceptions of a Grocery Store Tour: Comparison of Adultversus Teen-Led Education. C.J. Nikolaus, C.A. Liguori, S.M.
Nickols-Richardson. Univ. of Illinois at Urbana-Champaign.
D101 I896.15 Nudges: Fun, Motivational Messages
to Encourage and Reassure Parents in the Homestyles
Randomized Controlled Trial. C. Delaney, J.T. MartinBiggers, G. Povis-Alleman, N. Hongu, J. Worobey, C. ByrdBredbenner. Rutgers Univ. and Univ. of Arizona.
D102 II896.16 Nutrition Recommendations Critical to
Teach Low-Income Adults in EFNEP: U.S. Dietary Guidelines
Expert Panel Opinion. E. Murray, S. Baker, G. Auld. Colorado
State Univ.
D103 I896.17 The Effects of Nutrition Education on
Fruit and Vegetable Consumption in Food Pantry Clients. S.
St. Cyr, A. Bruzina, M. Linek, M. Butsch-Kovacic, S-Y. Lee.
Univ. of Cincinnati and Cincinnati Children’s Hosp. Med. Ctr.
D104 II896.18
Peer-Education
about
Weight
Steadiness (PAWS Club): Pilot Test of Family Menu Planning
Lesson for Parents and Their Young Adolescents. C.J. Nikolaus,
C.A. Liguori, A.N. Winslow, S.M. Nickols-Richardson. Univ.
of Illinois at Urbana-Champaign.
D105 I896.19 Using Skin Carotenoids to Assess
Potential Dietary Changes after One Academic Year in the
Shaping Healthy Choices Program. L.M. Nguyen, R.E.
Scherr, M. Dharmar, I.V. Ermakov, W. Gellermann, L. Jahns,
J.D. Linnell, C.L. Keen, S. Miyamoto, F.M. Steinberg, H.M.
Young, S. Zidenberg-Cherr. Univ. of California, Davis, Sch.
of Nursing, Davis Hlth. Syst., Sacramento, Image Technols.
Corp., Salt Lake City, USDA, Grand Forks, Univ. of California
Agr. and Nat. Resources and Penn State Col. of Nursing.
MONDAYNUTRITION
897. NUTRITION POLICY
Poster
(Sponsored by: Public Policy Committee)
Exhibit Halls A-D
Science Policy
1:45 pm–2:45 pm (II)
D106 II897.1
Adapting, Implementing, and Assessing
the Impact of the Shaping Healthy Choices Program through
UC CalFresh Partnerships. J.J. Bergman, J.D. Linnell, D.C.
Ginsburg, R.E. Scherr, K.M. Brian, R. Carter, S. Donohue,
L. Hoyos, S. Klisch, S. Lawry-Hall, A. Martin, M.A. Mills, J.
Pressman, K. Soule, W. West, S. Zidenberg-Cherr. Univ. of
California, Davis and Coop. Exts. Auburn, Oroville, Stockton,
San Luis Obispo and Placerville, CA.
D107 I897.2
Mining the Twitter-Sphere for Consumer
Attitudes towards Dairy. C.M. Whisner, H. Wang, S. Felix, R.
Maciejewski. Arizona State Univ.
D108 II897.3
FDA’s Evaluations of GRAS Food
Ingredients. J. Dausch. FDA, Bethesda.
D109 I897.4Validity
of
Anthropometric
Measurements, BMI and Child Growth Assessments Conducted
by Head Start Teachers: Training Needs for Longitudinal Child
Growth Surveillance. M.K. Esquivel, M.K. Fialksowski, C.R.
Nigg, K.L. Braun, F. Li, L. Wilkens, R.K. Novotny. Univ. of
Hawaii Manoa and Univ. of Hawaii Cancer Ctr.
D110 II897.5 New
Classification
Based
on
Anthropometric Indicators for Assessing Dual Burden of
Malnutrition in Young Children. R. Sibrian, P. Palma de
Fulladolsa. SG-SICA/PRESANCA, San Salvador.
D111 I897.6 Menu
Labeling:
Coming
to
a
Neighborhood Near You...or Is It? J.E. Green, R. DeWeese, C.
Lorts, P. Ohri-Vachaspati. Arizona State Univ.
D112 II897.7
Examining the Implementation of a
Regulatory Food Policy in High Schools: Experiences of
Principals and Food Service Administrators. M.L. Jensen, W.
González, E.A. Frongillo, R. Monge, A.J. Chinnock. Sch. of
Nutr., Univ. of Costa Rica, Arnold Sch. of Publ. Hlth., Univ. of
South Carolina and INCIENSA, Cartago, Costa Rica.
D113 I897.8
A Qualitative Evaluation of the Ontario
School Food and Beverage Policy Using an Implementation
Framework: Lessons Learned. R.Valaitis, R. Hanning,T. Orava.
Sch. of Publ. Hlth. & Hlth. Systs., Univ. of Waterloo, Canada.
898. SPORTS NUTRITION: NUTRITION, DIETARY
SUPPLEMENTS AND HUMAN PERFORMANCE
Poster
D115 I898.2 Sensation Seeking Behaviors and
Dietary Supplement Usage in Warfighters. A.M. Hatch,
A.J. DiChiara, J.J. Sepowitz, R.E. Cole, E.P. Merrill, H.R.
Lieberman, A.S. Bukhari. U.S. Army Res. Inst. of Envrn.
Med., Natick, MA.
D116 II898.3 Caffeine
Accentuates
Emotional
Responses, Not Emotion Regulation Choice. G.E. Giles, A.M.
Spring, H.L. Urry, J.M. Moran, C.R. Mahoney, R.B. Kanarek.
Tufts Univ. and U.S. Army Natick Soldier R&D and Engin. Ctr.
D117 I898.4Carbohydrate+Protein
Ingestion
Influences Recovery following a Marathon Run. M.J. Saunders,
C.R. DeWitt, M.C. Gross, A. Dillon Rios, C.J. Greever, K.A.
Murach, S.Y. Wineland, D.A. Baur, N.D. Luden. James
Madison Univ.
D118 II898.5 The
Effect
of
Protandim®
Supplementation on Athletic Performance and Oxidative Blood
Markers in Runners. G.S. Zavorsky, S.L. Ueberschlag, J.R.
Seay, A.H. Roberts, P.C. DeSpirito, J.M. Stith, R.J. Folz, K.A.
Carter, E.P. Weiss. Georgia State Univ., Univ. of Louisville,
Univ. of Kentucky, Case Western Reserve Univ. and Saint
Louis Univ.
D119 I898.6 Intense Exercise Increases NF-κB
Activity in Liver: Regulatory Effects of Quercetin. C. Gao, Z.
Wang, Y. Tang, L. Liu, X. Xiang, W. Xu, X. Zhang, J. Zhao,
Y. Yang. Chinese Ctr. for Dis. Control and Prevent., Beijing,
Huazhong Univ. of Sci. and Technol. and Wuhan Polytech
Univ., China.
D120 II898.7
Energy Drink Consumption by Online
College Students. L.O. Byerley. American Publ. Univ., WV.
D121 I898.8
In Vitro Comparative Absorption of
Creatine Compounds. S. Morgan, C. Ericson, J.W. Hartle.
Albion, UT.
D122 II898.9
Examining the Relationship between
Iron Status and Physical Performance in Chinese Women.
L.M. Pompano, J.D. Haas. Cornell Univ.
D123 I898.10 Coffee but Not Anticipation of Coffee
Alters the Outcome of Explosive Bench Pressing. B. Smith,
A. Feucht, G. Slack, J. Rogers, F. LaRock, R. Mendel, L.
Lowery. Univ. of Mount Union and Independent Licensed Res.
Nurse, Alliance, OH.
D124 II898.11Astaxanthin-Rich
Green
Alga
Haematococcus pluvialis Enhanced Extreme Endurance
Performance and Improved Heart Rate Recovery in Exercised
Rats. E. Yamashita, H. Lin, M. Narducci. AstaReal, Co.
Ltd., Osaka.
D125 I898.12
Effect of Aspartate Supplementation on
Athletic Performance and Testosterone Levels in Young Men. Z.
LaMacchia, B. Williams, P.J. Horvath. Univ. at Buffalo SUNY.
D126 II898.13 The Analysis of Essential Nutriment
Intake Deficiencies and the Body Composition Compartments in
College Athletes. A. Mendoza-Hernandez, B. Avila-Martinez,
V. Rocha, P. Sánchez-Quintero, A. Nuñez-Guzman. UPAEP,
Puebla, Mexico.
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D114 II898.1
Via Instant Coffee Enhances the Stretch
Reflex during Bench Pressing. G. Slack, J. White, A. Feucht,
S. Stepp, D. Hosier, A. Wise, S. Mohney, L. Lowery. Univ. of
Mount Union.
283
M
O
N
NUTRITIONMONDAY
FOOD SECURITY AND ITS CONNECTIONS TO
NUTRITION AND HEALTH
Poster
Nutrition RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D127 I899.1
Food Insecurity, Health, and Healthcare
Utilization among the Working Poor in the U.S. E.L.P. Sattler,
V. Bhargava. Univ. of Georgia.
D128 II899.2
The Usual Nutrient Intakes of U.S.
Children and Adolescents by Milk Drinking Behavior. Y. Zhao,
R. Bailey, C. Weaver, G. McCabe, H. Eicher-Miller. Purdue
Univ.
D129 I899.3
Psychological Distress Mediates the
Relationships between Household Food Insecurity and Sleep
Quality among Latinos with Type 2 Diabetes. A. BermúdezMillán, R. Pérez-Escamilla, S. Segura-Pérez, G. Damio, J.
Chhabra, C.Y. Osborn, J.A. Wagner. UConn Hlth., Yale Sch.
of Publ. Hlth., Hispanic Hlth. Council, Hartford, Hartford Hosp.
and Vanderbilt Univ. Med. Ctr.
D130 II899.4 Household
Food
Insecurity
Is
Associated with Higher Insulin Resistance and Blood Glucose
Levels in Latinos with Type 2 Diabetes. A. Bermúdez-Millán,
J.A. Wagner, S. Segura-Pérez, G. Damio, J. Chhabra, R.
Pérez-Escamilla. UConn Hlth., Farmington, Hispanic Hlth.
Council, Hartford, Hartford Hosp. and Yale Sch. of Publ. Hlth.
D131 I899.5
Food Security: Motivations to Volunteer
in Food Rescue Nutrition. T.Y. Mousa, J.H. Freeland-Graves.
Univ. of Texas at Austin.
D132 II899.6 Association of Household Food
Insecurity, Nutritional Status, Energy and Nutrients Intake in
Female-Headed Households from Culiacan, Sinaloa, Mexico.
D.A. Ochoa, I.A. Osuna-Ramirez, R. Pérez-Escamilla, C.G.
Plazas-Guerrero, M.D. Vergara-Jiménez. Univ. Autónoma de
Sinaloa, Mexico and Sch. of Publ. Hlth., Yale Univ.
D133 I899.7
Nutritional Impact of “Cruzada Nacional
Contra El Hambre” in México. V. Mundo Rosas, T. Shamah
Levy, I. Méndez Gómez-Humarán, B. Martínez Tapia. Natl.
Inst. of Publ. Hlth., Cuernavaca and Ctr. Invest. en Matemat.
A.C, Aguascalientes, Mexico.
D134 II899.8 Implementation
of
the
General
Guidelines for the Sale and Distribution of Food and Drinks
Prepared and Processed in the Schools of the National
Education System in Mexico, the Universidad Iberoamericana
Case. A.B. Perez-Lizaur, L.I. Moreno. Univ. Iberoamericana,
Mexico City.
D135 I899.9
Sustainable Diets for Food Security in
the Middle East and North Africa Region. N. Hwalla, R. Bahn,
S. El Labban. American Univ. of Beirut.
D136 II899.10 Cross-Sectional but Not Longitudinal
Measures of Food Insecurity Are Associated with the Rate
of Weight Gain during Pregnancy in Northern Uganda. B.K.
Natamba, S. Mehta, F. Vermeylen, E.M. Widen, S. Ghosh,
J.K. Griffiths, P.M. Brannon, S.L. Young. Harvard Univ.,
Gulu Univ., Uganda, Cornell Univ., Columbia Univ. and Tufts
Univ., Boston.
284
D137 I899.11 The Association between DIetary
Diversity Score and Iron Deficiency Anemia among
Reproductive-Aged Women in Ghana. C. Kubuga, K. Lee, S.
Song, W.O. Song. Michigan State Univ. and Univ. for Develop.
Studies, Ghana.
D138 II899.12 High Levels of Food Insecurity Were
Observed among HIV, TB, and HIV/TB CoiInfected Outpatients
in Northern Uganda. M.M. Blakstad, S. Mehta, J. Kuule, B.K.
Natamba. Cornell Univ., Uganda Ministry of Hlth., Entebbe,
Harvard Univ., Boston and Gulu Univ., Uganda.
D139 I899.13 Food Insecure Women with Lower
Education Report More Health Problems in a Global Sample
of Individuals. D. Dallmann, M. Miller, H. Melgar-Quiñonez.
McGill Univ.
D140 II899.14
Divorced Women Who Are in Informal
Unions Are Most Vulnerable to Food Insecurity. D. Dallmann,
G.S.D. Marquis, E.K. Colecraft, S. Clark, R. Aryeetey. Sch.
of Dietetics and Human Nutr., McGill Univ., Univ. of Ghana and
McGill Univ., Montreal.
D141 I899.15 Nutrition Resource Associations with
Food Security Parameters among Mexican-Heritage Seniors:
A Structural Equation Model Analysis. B.D. Bustillos. Texas
A&M Hlth. Sci. Ctr., San Antonio.
POLICY AND SYSTEMS APPROACHES IN
COMMUNITY AND PUBLIC HEALTH NUTRITION
Poster
Nutrition RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D142 II900.1 Food
Purchasing
Patterns
of
Supplemental Nutrition Assistance Program Participants. N.
Sanjeevi, J.H. Freeland-Graves. Univ. of Texas at Austin.
D143 I900.2
Academic and Industry Joint Efforts
to Include Vitamins and Minerals in Newly Implemented
Regulation in Japan for the Functional Claims of Health Foods
Named Food with Functional Claims. H. Amagase, K. Sueki, K.
Abe, J. Yamauchi, A. Wada, H. Ichinose, S. Shigeoka. Amway
Japan, Tokyo, Vitamin Soc. of Japan Task Force, Kyoto, Assn.
of Intl. Food and Nutr., Eizai Food Chem. Co. Ltd. and Natl.
Inst. of Hlth. and Nutr., Tokyo, Kobe Pharmaceut. Univ., Tokyo
Inst. of Technol., Yokohama and Kinki Univ., Japan.
D144 II900.3
Advancing the Science of Dietary
Patterns Research: Developing a Framework and Leveraging
a Complex Systems Approach. J. Reedy, R. Hammond, E.
Hennessy, S.M. Krebs-Smith. NCI, NIH and Brookings Instn.,
Washington, DC.
D145 I900.4
A China-USA Comparative Study of
Peer Influence on Childhood Obesity and Eating Behavior:
Social Network Analysis and Agent-Based Modeling. H. Xue,
J. Zhang, Y. Wang. Univ at Buffalo, SUNY and Med. Univ of
South Carolina Hosp. Authority.
D146 II900.5
Impact of Citation Network on the
Diffusion of Systems Science Simulation Approaches in HealthRelated Research. S. Liu, H. Xue, Y. Wang. Southwestern Univ
of Finance and Econ., China and Univ at Buffalo SUNY.
MONDAYNUTRITION
D147 I900.6
Using a Community-Based Participatory
Approach to Design Changes to the Food Environment in a
Central American Immigrant Community. U. Colon-Ramos, M.
Edberg, S.D. Cleary, W.D. Evans, E. Andrade. Milken Inst.
Sch. of Publ. Hlth., George Washington Univ.
D148 II900.7
School Food Policies and Practices in
New York City Public Schools. M. Pflugh Prescott, B. Dixon.
Colorado State Univ. and Syracuse Univ.
HEALTH DISPARITIES AND PROMOTING
HEALTH IN DIVERSE POPULATIONS
Poster
Nutrition RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D149 I901.1
Impact of Casinos on Key Dimensions
of Health and Nutrition: Qualitative Findings from American
Indian Gaming Communities in California. S.R. Kodish, J.
Gittelsohn, V.M. Oddo, J.C. Jones-Smith. Johns Hopkins
Bloomberg Sch. of Publ. Hlth.
D150 II901.2
Vitamin B12 and Folate Status in
Pregnant Adolescents and Their Infants. J.L. Finkelstein, R.
Guillet, E.K. Pressman, T.R. Kent, K.O. O’Brien. Cornell Univ.
and Univ. of Rochester Med. Ctr.
D151 I901.3
Assess the Prevalence of Nutrition
Related Diseases and Risk Factors for Chronic Diseases in
Mamfe Subdivision in Cameroon. S.A. Besong, P. Agbo, A.A.
Assam, E.E. Assam, B.C. Besong, J.O. Enoru. Delaware
State Univ., RAPHAS HANDS Fndn., Dover, DE, First Choice
Home Hlth. Agcy., Homewood, IL and MECA-USA Inc.,
Camden, DE and Concord, OH.
D152 II901.4 Nutritional
Health Attitudes
and
Behaviors and Their Associations with the Risk of Overweight/
Obesity among Michigan Migrant and Seasonal Head Start
Staff. S. Song, V. Nieves, W.O. Song. Michigan State Univ.
D153 I901.5
The Relationship of Full Time Family
Care to Food Security in U.S. - and Foreign - Origin Hispanic
Households. A.C. McClain, K.L. Dickin, J. Dollahite.
Cornell Univ.
D154 II901.6
A Palauan Healthy Lifestyle: Steps
toward Tailoring Local Resources and Health Information for
Non-communicable Disease Prevention and Intervention.
K.J. Farr, Z. Cohen, K. Nielsen, A. Rombod Rahimian, I.
Appanaitis, N. Hongu. Univ. of Arizona and Ministry of Hlth.,
Republic of Palau.
D155 I901.7
Dietary Quality and Food Group Intakes
of Korean Elderly by Chewing Ability Using the 2013 Korea
National Health and Nutrition Examination Survey Data. Y.S.
Lim, S.H. Kwon, C.R. Kim, Y.M. Lee, S. Kwon, O.S. Kim, H.Y.
Kim, H-R. Park. Myongji Univ., Honam Univ. and Jangan Univ.,
South Korea.
D156 II901.8
Barriers, Facilitators, and Strategies to
Support Healthy Eating among Recent Hispanic Immigrants’
Mothers Living in a Food Swamp: A Photovoice Project. U.
Colon-Ramo, E. Cremm, I. Rivera, M. Edberg. Global Hlth.
and Milken Inst. Sch. of Publ. Hlth. George Washington Univ.
D157 I901.9
High Overweight/Obesity Risk among
Children Enrolled in Michigan Migrant and Seasonal Head
Start Programs, 2012 C. Nance-Panek, S. Song, Y.M. Lim,
E.T. Crockett, W.O. Song. Michigan State Univ.
D158 II901.10 Community Perspectives of Health
Care and Education Provided through a Student-Run Free
Clinic in an Urban Setting. J. Phelps, L. White, S. Parker. Univ.
of Arkansas for Med. Sci. and Oklahoma State Univ.
D159 I901.11
Promotora-Academic Partnership to
Reduce Nutritional Health Disparities among Mexican-Heritage
Families in Texas Border colonias J. Sharkey, R. Umstattd
Meyer, J. St. John. Texas A&M Sch. of Publ. Hlth., Baylor Univ.
and Texas Tech Univ., Abiline.
D160 II901.12 Partnership between a Historically
Black College and a Community Health and Wellness Center
to Engage African American Men in Community Participatory
Research and the Development of Biomarkers of Diabetic
Nephropathy. R. Sedighi, O.E. Jegede, J. Pinder, S.J.
Sumner, S.H. Harrison, R.H. Newman, E.M. Ongeri. North
Carolina A&T State Univ., Cone Hlth. Community Hlth. and
Wellness Ctr., Greensboro and Res. Triangle Inst. Intl., NC.
D161 I901.13 Usual Dietary Intake among Children
2-5 Years in a Community at High Risk for Obesity: Comparison
to Age-Matched NHANES Data, 2009-2012 B.R. Markides,
S.H. Crixell, L. Biediger-Friedman. Texas State Univ.
D162 II901.14
Nutritional Status of Pesticide-Exposed
Individuals. R. Valdes-Ramos, A.L. Guadarrama-López, B.E.
Martínez-Carrillo, A.D. Benítez-Arciniega, G. PachecoLópez, J.L. Domínguez. Autonomous Univ. of State of Mexico,
Toluca and Autonomous Metropolitana Univ., Lerma, Mexico.
D163 I901.15 Community Support Groups Improved
Feeding Practices in Infants and Young Children in Remote
Areas in Vietnam. T.T. Nguyen, S. Alayón, P.H. Nguyen, N.
Hajeebhoy, C.T. Do, E.A. Frongillo. FHI 360, Vietnam, FHI
360, Save the Children and IFPRI, Washington, DC and Univ.
of South Carolina.
D164 II901.16 My Grandmother’s Pot: Caribbean
Immigrant Cooking Skills and Dietary Acculturation. M.F.
Horlyck-Romanovsky, K. Russell, M-C. Yeh. Grad. Ctr. of
CUNY, Brooklyn Col. and Sch. of Urban Publ. Hlth. at Hunter
Col., CUNY.
D165 I901.17Differences
in
Whole
Grain
Consumption Patterns by Ethnicity: Results from NHANES
2011-2012 and the Food Patterns Equivalents Database 20112012 C.K. Gugger, S. Bidwai, N. Joshi, B. Garcia-Bailo. Gen.
Mills Inc., Minneapolis, Mumbai and Toronto.
D166 II901.18
Crosstalk between the Risk of Diabetes
and Iron Status in Different Ethnic Groups. D. Yang, M.E. Kalan,
J. Han. Univ. of Louisville and North Carolina A&T State Univ.
D167 I901.19
The Effects of Omega 3 Supplementation
on Reducing the Neuropathy Pain Symptoms in Hispanics with
Type-2 Diabetes. S.M. Alshahrani, W.L. Beeson, I. PerezPaquien, A. Firek, Z. Cordero-MacIntyre, M. De Leon. Sch. of
Publ. Hlth. and Sch. of Med., Loma Linda Univ. and J.L. Pettis
Mem. VA Med. Ctr. and Whittier Col., CA.
D168 II901.20
The
Effects
of
Omega-3
Supplementation on the Lipid Profile and Adipose Indices in
Hispanics with Type 2 Diabetes Mellitus. C.V. Mota, I. PerezPaquien, A. Firek, W.L. Beeson, Z.R. Cordero-MacIntyre,
M. De Leon. Loma Linda Univ. Sch. of Publ. Hlth., Med. Ctr.
and Veterans Affairs, Loma Linda Univ. Sch. of Med. and
Whittier Col.
285
M
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NUTRITIONMONDAY
D169 I901.21 Is There Evidence of Demographic
Disparity in Provision and Outcomes of Artificial Nourishment?
K.Y. Yao, D.S. Seres, B. Lebwohl, M. Burgermaster. Mailman
Sch. of Publ. Hlth., Columbia Univ. and Columbia Univ.
Med. Ctr.
D170 II901.22
Consumption of Cultural and AmericanStyle Foods among Young Women of Cambodian Heritage.
J.L. Nelson-Peterman, L. Sibeko, L.S. Cordeiro. Framingham
State Univ. and Univ. of Massachusetts Amherst.
D171 I901.23 Nutrition Education for Low Income
Population through Social Marketing: Insight from Cooperative
Extension Agents. R. Hagues, S. Stotz, A. Childers, J.S.
Lee, J. Phua, J. Hibbs, D. Murray. Samford Univ. and Univ.
of Georgia.
D172 II901.24 Nutrition Education for Low-Income
Population through Social Marketing: Insight from SNAP-Ed
Eligible Participants. R. Hagues, A. Childers, J.S. Lee, J.
Phua. Samford Univ. and Univ. of Georgia.
D173 I901.25 Acculturation, Diet and Psychological
Health of Asian International Students at the University of
Delaware. H. Jiang. Purdue Univ.
D174 II901.26 Examination of Dietary Behaviors of
South Asians for the Development of Culturally Appropriate
Nutrition Education Program. Z. Qamar, R. Misra. Texas A&M
Univ. and West Virginia Univ.
D175 I901.27 Attitudes, Beliefs and Promotion of
Fruits and Vegetables by Multicultural Students from an Urban
Middle School in Worcester, MA. E. Harrington, F. Mangan, L.
Sullivan-Werner, Z. Barros, L. Sibeko. Stockbridge Sch. of
Agr., Univ. of Massachusetts Amherst.
902. NUTRITIONAL EPIDEMIOLOGY: NUTRITION
AND CHRONIC DISEASE EPIDEMIOLOGY
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D176 II902.1
Autism Linked to Alcohol and Sugar
Intake. R.J. Shamberger. King James Med. Lab., Kirtland, OH.
D177 I902.2
The Subjective Level of Stress, Alcohol
Consumption and Obesity in Koreans. M. Doo, S-J. Yoon, H-J.
Kim, Y. Kim. Ewha Womans Univ., Grad. Sch. of Publ. Hlth.,
Korea Univ. and Seoul Natl. Univ. Hosp., South Korea.
D178 II902.3
Differential
Predictors
of
Cardiometabolic Risk among College-Aged Males and
Females. M. MacArthur, I.E. Lofgren. Univ. of Rhode Island.
D179 I902.4
100% Fruit Juice and Measures of
Glycemic Control and Insulin Sensitivity: A Meta-analysis of
Randomized Controlled Trials. M.M. Murphy, E.C. Barrett,
L.M. Barraj. Exponent Inc., Washington, DC.
D180 II902.5
Comparison of Salt Intake between
the Patients with Diabetes Mellitus and/or Hypertension,
and Healthy Subjects. N. Motoyuki, Y. Ishihara. Kurume
Univ., Japan.
D181 I902.6 The Association between Dietary
Factors and the Incident of Type 2 Diabetes: A Case-Control
Study. Y-b. Ye, Y-m. Chen, W. Lu, Y-b. Li, A-l. Chen, S. Fang,
S-y. Zhuo. First Affil. Hosp. of Sun yat-sen Univ. and Sun Yatsen Univ., China.
286
D182 II902.7
Red Blood Cell Fatty Acids and Incident
Diabetes Mellitus in the Women’s Health Initiative Memory Study.
W.S. Harris, J. Luo, J.V. Pottala, K.L. Margolis, M.A. Espeland,
J.G. Robinson. OmegaQuant Analytics LLC, Univ. of South
Dakota Sch. of Med., Indiana Univ., Hlth.Partners Inst. for Educ.
and Res., Minneapolis, Wake Forest Univ. and Univ. of Iowa.
D183 I902.8
Dietary Intake of Isoflavone and AllCause Mortality in Women with Breast Cancer: The Breast
Cancer Family Registry. D.E. Haslam, E. John, M.B. Terry, J.
Knight, I. Andrulis, M. Daly, S. Buys, F.F. Zhang. Tufts Univ.
Friedman Sch. of Nutr. Sci. and Policy, Cancer Prevent. Inst.
of California, Fremont, Columbia Univ., Mount Sinai Hosp.,
Toronto, Fox Chase Cancer Ctr. and Univ. of Utah.
D184 II902.9 A Review and Meta-analysis of
Prospective Studies of Red and Processed Meat and Pancreatic
Cancer. P.E. Miller, D. Alexander. EpidStat Inst., Ann Arbor.
D185 I902.10
Individual and Neighborhood Factors of
Serum Levels of 25-Hydroxyvitamin D and C-Reactive Protein:
Evidence from the National Health and Nutrition Examination
Survey (NHANES) W. Chai, J.X. Fan, M. Wen. Univ. of
Nebraska-Lincoln and Univ. of Utah.
D186 II902.11
Dietary Total Antioxidant Capacity Was
Associated with Reduced Blood Risk Factors for Cardiovascular
Disease in U.S. Adults. K. Kim, T.M. Vance, O.K. Chun. Univ.
of Connecticut.
D187 I902.12 Higher Diet Quality and Decreased
Inflammation in Young Women. Q. Chen, C.C. Cramoy, R.
Magner, A.G. Ronnenberg, E.R. Bertone-Johnson, L.M.
Troy. Univ. of Massachusetts Amherst.
D188 II902.13 Mediterranean Diet and Changes in
Weight among Older Puerto Rican Adults. S.J. Bigornia, S.E.
Noel, K.L. Tucker. Univ. of Massachusetts Lowell.
D189 I902.14
“When It Comes to Diet, I Know What
I’m Doing Wrong” Perception of Diet Quality Is Inversely
Associated with Body Weight in U.S. Adults. R. Nouri, J.A.
Vernarelli. Fairfield Univ.
D190 II902.15
Plasma Amino Acids and Mortality in a
Middle-Aged and Older Chinese Population during 6-Year FollowUp. L. Sun, X. Lin, R. Zeng. Shanghai Inst. for Biol. Sci., CAS.
D191 I902.16 Elevated Early Adolescent Body Fat
Measures Predict Increased Blood Pressure after Ten Years
in Black and White Girls. S.E. Ferreira, M.R. Singer, M.L.
Bradlee, S.R. Daniels, L.L. Moore. Boston Univ. Sch. of Med.
and Univ. of Colorado Sch. of Med., Aurora.
903. NUTRITIONAL EPIDEMIOLOGY: RESEARCH
WITH DIETARY SUPPLEMENTS AND
BIOACTIVE COMPOUNDS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D193 II903.1 Monitoring
Analytical
Ingredient
Content in Adult Multivitamin/Mineral Products for the Dietary
Supplement Ingredient Database. P.A. Gusev, K.W. Andrews,
P.T. Dang, F. Han, S. Savarala, P.R. Pehrsson, J.T. Dwyer,
J.M. Betz, L.G. Saldanha, R.B. Costello, L.W. Douglass.
USDA, Beltsville, MD, ODS, NIH and Consult. Statistician,
Longmont, CO.
MONDAYNUTRITION
D194 I903.2
The Randomization to Randomization
(R2R) Method: An RCT Application with Caffeine. M.M.
Jeansonne, M.A. Parman, A.J. Idigo, B.J. George, K.R.
Fontaine, G.R. Dutton, T. Soleymani, D.B. Allison. Univ. of
Alabama at Birmingham.
D195 II903.3 Changes
in
Antioxidant
and
α-Glucosidase Inhibitory Activities of Coffee Bean Extracts
by Heat Processing. J. Lee, S.I. Jang, B.H. Kang, M.S. Lee,
E.M. Park, Y.I. Kwon. Hannam Univ., South Korea and Univ.
of Maine.
D196 I903.4 Postprandial Blood Glucose Level
Reducing Effect of Low Molecular Weight Chitosan
Oligosaccharide, GO2KA1, in Health Individuals. Y-R. Kang,
H-Y. Choi, J-Y. Lee, J-B. Oh, J.S. Kim, J-W. Lee, Y-C. Kim, E.
Apostolidis, Y-I. Kwon. Hannam Univ., South Korea, Univ. of
Massachusetts Amherst, Kunpoong Bio Co. Ltd., South Korea
and Framingham State Univ.
D197 II903.5 Biochemical Comparison of AAC1
Enriched Chicken Broth to Homemade Chicken Broth: Potential
Benefits to Joint Health. P. Durham, J.L. Hawkins. Missouri
State Univ.
D198 I903.6 In Vitro Antioxidant Activity and
α-Glucosidases Inhibitory Potential of Amadori Rearrangement
Compound, Lysinyl-Fructose. H-Y. Choi, S-H. Jo, K-S. Ha, H-D.
Jang, Y-I. Kwon. Hannam Univ., South Korea and Framingham
State Univ.
904. AGING: NUTRITION AND
CARDIOMETABOLIC HEALTH
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D199 II904.1
Consuming < or > 0.5 Servings of
Red Meat per Day Does Not Have a Negative Impact on
Cardiovascular Disease Risk Factors: A Systematic Review
and Meta-analysis of Randomized Controlled Trials. L.E.
O’Connor, J. Kim, W.W. Campbell. Purdue Univ.
D200 I904.2 The Association between Adipose
Tissue n-3 Fatty Acids and Blood Lipids. C. Heskey, K.
Jaceldo-Siegl, J. Sabate, S. Rajaram. Loma Linda Univ.
D201 II904.3
Increased Whole Body β-Hydroxy-βMethylbutyrate Production in Chronic Obstructive Pulmonary
Disease. D. Walker, J. Thaden, A. Wierzchowska, M. Engelen,
N. Deutz. Texas A&M Univ.
D202 I904.4
Differential Relationship between Thigh
and Calf Intramuscular Adipose Tissue Depots and Indices of
Metabolic Health in Older Overweight and Obese Adults. R.E.
Bergia, J.E. Kim, W.W. Campbell. Purdue Univ.
D203 II904.5
The Fat Content of Milk Does Not Affect
the Plasma Glucose and Insulin Responses to a Meal. J. Li, E.
Janle, W.W. Campbell. Purdue Univ.
D204 I904.6Whole
Body
Leucine
and
α-Ketoisocaproate Turnover and Transamination in Chronic
Obstructive Pulmonary Disease. D. Walker, J. Thaden, A.
Wierzchowska, M. Engelen, N. Deutz. Texas A&M Univ.
D205 II904.7
Relation of Total Sugars and FructoseContaining Sugars with Risk of Cardiovascular Disease: A
Systematic Review and Meta-analysis of Prospective Cohort
Studies. T.A. Khan, S. Blanco-Mejia, R. de Souza, C.W.C.
Kendall, J.L. Sievenpiper. St. Michael’s Hosp., Toronto,
Univ. of Toronto, McMaster Univ., Hamilton, ON and Univ. of
Saskatchewan, Canada.
D206 I904.8
Following a Mediterranean Diet for
3-Months Reduces Home Measured Systolic Blood Pressure
in Older Australians: Results from the Mediterranean Diet for
Cognition and Cardiovascular Health in the Elderly (MedLey)
Trial. K. Murphy, C. Davis, J. Bryan, C. Wilson, R. Woodman,
J. Hodgson. Univ. of South Australia, Sch. of Med., Flinders
Univ. and Royal Perth Hosp, Univ. of Western Australia.
D207 II904.9 Iodine Status Is Associated with
Dyslipidemia in U.S. Adults. K.W. Lee, D. Shin, M.S. Cho,
W.O. Song. Michigan State Univ. and Ewha Womans Univ.,
South Korea.
D208 I904.10
A High Flavonoid Diet Does Not Improve
Markers of Insulin Resistance and Subclinical Inflammation
in Overweight and Obese Men and Women. M. Lefevre, R.
Ward, J. Bergeson, N. Hergert, J. Hergert, S. Aguilar. Utah
State Univ.
D209 II904.11 A Vegan Diet Rich in Fats of Plant
Origin May Reverse Coronary Artery Disease. M.A. Mejia, A.
Sanchez, J. Sanchez, E. Runte. Andrews Univ., MI, NEWSTAR
Lifestyle Ctr., Weimar, CA, Doctors Hosp. of Manteca, CA and
Family Practice, Sonora, CA.
D210 I904.12 The Efficacy of High Fat Load Liquid
Meal on Postprandial Insulin Level in Postprandial Insulin
Resistance Population. F. Wang, F. Liu, H. Cai, L. Yang, G.
Sun. Sch. of Publ. Hlth., Southeast Univ., Nanjing and Sch. of
Publ. Hlth., Ningxia Med. Univ., China.
D211 II904.13 Micronutrient Deficiencies in Patients
with Heart Failure: Relationships with Body Mass Index and
Age. P.M. Shetty, P.J. Hauptman, L.K. Landfried, K.J. Patel,
E.P. Weiss. Sch. of Med., Saint Louis Univ.
D212 I904.14 The Characteristics and Stability of
T0901317 Nanovesicles. J. Liu, S. Wang. Texas Tech Univ.
D213 II904.15 Fuzhuan Tea Reverses Western DietInduced Arterial Stiffness in Mice. D. Lee, M. Battson, D.
Jarrell, K. Sevits, T. Weir, K. Cox-York, C. Gentile. Colorado
State Univ.
D214 I904.16 Effects of Strawberry Consumption
on Vascular Parameters in Pre- and Stage 1-Hypertensive
Postmenopausal Women: A Randomized, Double-Blind,
Placebo-Controlled Trial. B.H. Arjmandi, R.G. Feresin, S.A.
Johnson, A. Figueroa, S. Pourafshar, N. Navaei, J. Campbell,
S. Jaime, M.L. Elam, S. Alvarez-Alvarado, N.S. Akhavan, K.
Brummel-Smith, G. Tenenbaum. Florida State Univ., Univ. of
Arkansas for Med. Sci., Colorado State Univ. and California
State Polytech Univ., Pomona.
D215 II904.17 The Effect of Higher Protein Intake
during Energy Restriction-Induced Weight Loss on Counts of
Intermediate and Classical Monocytes and Their Relations to
Lipid-Lipoprotein Profile and C-Reactive Protein. G. Lin, J.E.
Kim, J. Zhou, W.W. Campbell. Purdue Univ.
D216 I904.18 Choline and Its Metabolites Are
Differentially Associated with Cardiometabolic Risk and Cardioand Cerebro-vascular Disease. A.J. Roe, A.H. Lichtenstein,
I.H. Rosenberg, E.J. Johnson, T.M. Scott. Univ. of Idaho and
USDA at Tufts Univ.
287
M
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NUTRITIONMONDAY
D217 II904.19Coconut
Oil
Supplementation:
An Innovative Strategy for Cardiovascular Disease Risk
Reduction. C. Thompson-Felty, C.S. Johnston, A. Ryder.
Arizona State Univ.
D218 I904.20 Endothelial Function Assessment in
Nutritional Research Studies: A Comparison of Two Arterial
Occlusion Sites for Assessing Reactive Hyperemia Using a
Peripheral Arterial Tonometry Device. L.R. Woodhouse, Y.
Adkins, E. Bonnel, J.M. Peerson. USDA, Davis.
D219 II904.21
Genistein Increased Hepatic Cholesterol
Uptake via a JNK Mediated Activation of SREBP-2 and LDLR
Expression. S-M. Lee, M. Kartawijaya, Y. Kim. Yonsei Univ.,
South Korea.
D220 I904.22Higher
Fruit
and
Vegetable
Consumption May Be Associated with Improved Lipid Profiles
in Individuals with Metabolic Syndrome. N. Navaei, S.A.
Johnson, S. Pourafshar, N.S. Akhavan, M.L. Elam, E. Foley,
E.A. Clark, B.H. Arjmandi. Florida State Univ., Colorado State
Univ., Ctr. for Adv. Exer. and Nutr. Res. on Aging, Tallahassee
and California State Polytech Univ., Pomona.
D221 II904.23Sugary
Beverage
and
Food
Consumption and Leukocyte Telomere Length Maintenance
in Pregnant Women: A Pilot Study. C.W. Leung, B.A. Laraia,
K. Coleman-Phox, N.R. Bush, J. Lin, E.H. Blackburn, N.E.
Adler, E.S. Epel. UCSF and Sch. of Publ. Hlth., Univ. of
D222 I904.24 Antiseptic Mouthwash Use and Effect
on Resting Metabolic Rate and Blood Pressure among Healthy
Females: A Randomized, Double-Blind, Crossover Study.
M.L. Sundqvist, J. Lundberg, E. Weitzberg. Karolinska
Inst, Stockholm.
D223 II904.25 Dairy Consumption Is Associated
with Reduced Plasma Triglycerides and Changes in Body
Composition in Overweight and Obese Brazilian Adults: A 12Week Intervention Study. K. McLellan, A.C. Diegoli. Texas
Inst. for Kidney and Endocrine Disorders, Lufkin, TX and São
Paulo State Univ., Botucatu.
D224 I904.26 Alcohol Interrupts Adipose Tissue
Maturation and Attenuates Adiponectin Expression in 3T3F442 Pre-adipocytes. M.S. Shafiei, S. Juma, C. Prasad, V.
Imrhan, P. Vijayagopal. Texas Woman’s Univ.
D225 II904.27
SSB Assessment in a Teaching Primary
Care Clinic Involving Family Practice Residents: A Feasibility
Study Over Three Months. M. Nirmalraj, J. Neme, H. Mathews,
B. Khandalavala. Univ. of Nebraska Med. Ctr.
D226 I904.28 Egg Consumption May Be Associated
with Improved Lipid Profiles and Blood Glucose Levels in Men
and Women with Metabolic Syndrome. S. Pourafshar, S.A.
Johnson, N. Navaei, N.S. Akhavan, M.L. Elam, E. Foley,
E.A. Clark, B.H. Arjmandi. Florida State Univ., Colorado State
Univ. and California State Polytech Univ., Pomona.
288
905. DAIRY AND YOGURT: HEALTH AND
NUTRITION EFFECTS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D227 II905.1
Application of HACCP on the SmallScale Manufacture of a Food Product (Pudding) S. Almalky.
Jeddah, Saudi Arabia.
D228 I905.2
Pre-meal Low-Fat Yogurt Consumption
Reduces Postprandial Hyperglycemia and IL-6 in Apparently
Healthy Obese Women. R. Pei, D. DiMarco, K. Putt, D. Martin,
R. Bruno, B. Bolling. Univ. of Wisconsin-Madison, Univ. of
Connecticut and The Ohio State Univ.
D229 II905.3
Despite Higher n-6 PUFAs, Butter
Remains a Reliable Source of Saturated Fats across the World.
S. Ghosh, A. Botta. Univ. of British Columbia-Okanagan.
D230 I905.4
Dairy Foods: Current Evidence of Their
Effects on Bone, Cardiometabolic, Cognitive, and Digestive
Health. J. Hess, S. Jonnalagadda, J. Slavin. Univ. of
Minnesota, St. Paul and Kerry, Beloit, WI.
D231 II905.5
Modelling Substitution of Foods: A Tool
to Improve Diet Quality. R.J. Weill, M.E. Zapata, M. Domet,
E. Clerfeuille, E. Carmuega. Danone Nutr. Res. and CESNI,
Buenos Aires and Danone Nutr. Res.,Palaiseau, France.
D232 I905.6 The Effect of Yogurt on Human
Body Weight: A Systematic Review and Meta-analysis of
Randomized Experiments. K.A. Kaiser, M.M. Jeansonne,
A.W. Brown. Univ. of Alabama at Birmingham.
D233 II905.7
Dairy Food Intake and Perceptions
1995 to 2009: Is It Time to Promote Dairy Food Consumption?
D.A. Kerr, X. Meng, A. Devine, R.L. Prince, C.M. Pollard. Sch.
of Publ. Hlth., Curtin Univ., Sch. of Med., Flinders Univ., Sch. of
Exer., Biomed. and Hlth. Sci., Edith Cowan Univ., Sch. of Med.
and Pharmacol., Univ. of Western Australia and Dept. of Hlth.
WA, Perth.
D234 I905.8
Milk and Dairy Foods and Growth
Parameters among Adolescents. M. Nezami, J. Sabate, L.
Beeson, G. Segovia-Siapco. Loma Linda Univ.
D235 II905.9
Low-Fat Yogurt Consumption Reduces
Markers of Chronic Inflammation in Apparently Healthy Lean
and Obese Women. R. Pei, D. DiMarco, K. Putt, D. Martin,
R. Bruno, B. Bolling. Univ. of Wisconsin-Madison, Univ. of
Connecticut and The Ohio State Univ.
D236 I905.10 Consumption of Cheese and Nutrient
Intake of the U.S. Population. S.E. Noel, S. Saklani, J.E. Maras,
S.J. Bigornia, K. Rubin, K.L. Tucker. Univ. of Massachusetts
Lowell, Northeastern Univ. and The Kraft Heinz Co.
MONDAYNUTRITION
ENERGY BALANCE, MACRONUTRIENTS AND
WEIGHT MANAGEMENT
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D237 II906.1
Diet Quality Is Lower and Energy
Intake Greater on Weekends Than Weekdays: A One-Year
Longitudinal Study of Midlife Women. L. Jahns, L.K. Johnson,
S.K. Raatz, A.J. Scheett, K. Stote. USDA, Grand Forks, Univ.
of North Dakota and SUNY Empire State Col.
D238 I906.2
Almond Form and Processing Impacts
Metabolizable Energy Value in Humans. D.J. Baer, S.K.
Gebauer, J.A. Novotny. USDA, Beltsville, MD.
D239 II906.3
Environmental Cues Assist in Weight
Management. A.K. Thaw. Millsaps Col., MS.
D240 I906.4
Increases in the Lean and Adipose
Tissues Are Not Influenced by the Speed of Body Weight Gain
in Growing Rats. K. Okamura, Y. Tai, E. Kondo, M. Maeda, H.
Hasegawa. Osaka Univ. Hlth. Sport Sci.
D241 II906.5
Correlation between Total Daily Energy
Expenditure and Progression of Amyotrophic Lateral Sclerosis
in Men and Women. J. Lee, S.H. Kim, Y. Park. Hanyang Univ.
and Hanyang Univ. Hosp., Seoul.
D242 I906.6
Liquid Calories from Sugars Do Not
Increase Body Weight More Than Solid Calories: A Systematic
Review and Meta-analysis of Controlled Feeding Trials. J.C.
Noronha, V. Choo, S. Blanco Mejia, E. Viguiliouk, V. Jayalath,
C. Braunstein, C.W.C. Kendall, J. Sievenpiper. Fac. of Med.,
Univ. of Toronto, St. Michael’s Hosp., Toronto and Univ. of
Saskatchewan Col. of Pharm. and Nutr.
D243 II906.7
Energy Balance Teaching Tool for
Community Use: What University Nutrition Faculty and
Community Nutrition Educators Want. N. Hongu, A. Lindsay,
E. Larson-Meyer, L.B. Houtkooper, P.J. Gallaway, M.M.
Manore. Univ. of Arizona, Univ. of Nevada, Las Vegas, Univ.
of Wyoming and Oregon State Univ. Col. of Publ. Hlth. and
Human Sci.
D244 I906.8
Effect of Stimulation to the Oral Cavity
on Diet-Induced Thermogenesis and the Substrate Oxidation
of Macronutrients. Y. Hamada, N. Hayashi. Grad. Sch. of
Decision Sci. and Technol., Tokyo Inst. of Technol.
D245 II906.9
Effect of Low-Glycemic Index/Load
Diets on Body Weight: A Systematic Review and Meta-analysis.
C.R. Braunstein, S. Blanco Mejia, E. Stoiko, J.C. Noronha,
V. Choo, V. Ha, L. Augustin, D.J.A. Jenkins, C.W.C. Kendall,
J.L. Sievenpiper. Univ. of Toronto, St. Michael’s Hosp.,
Toronto, McMaster Univ., Hamilton and Univ. of Saskatchewan
Col. of Pharm. and Nutr.
D246 I906.10
Metabolic Behavior, Body Composition
and Satiety Associated with Egg Consumption in Healthy Young
Population. J.A. Fierros-Valdez, N.G. Valenzuela-Rubio,
D.A. Ochoa-Acosta, F.H. Castro-Sanchez, M. DominguezRodriguez, M. Vergara-Jimenez. Sch. of Nutr. and Gastron.,
Autonomous Univ. of Sinaloa, Mexico.
D247 II906.11 The Influence of Beverage Choice on
Body Weight Over 4 Weeks. E.C. Johnson, J.D.C. Adams,
L.T. Jansen, C. Capitain-Jiménez, S.A. Kavouras. Univ. of
Wyoming and Univ. of Arkansas.
D248 I906.12 Gut Hormone Secretion by Dietary
Maltooligosaccharide Chemosensation in Small Intestine
Enteroendocrine Cells. M.M.M. El Hindawy, C.Y. Kim, B.R.
Hamaker. Purdue Univ. and Yeungnam Univ., South Korea.
D249 II906.13
Effects of Exercise, Caloric Restriction
and Subsequent Weight Regain following the Loss of Ovarian
Function on Mitochondrial Respiration. R. Oljira, M. Jackman,
R. Foright, J. Houck, G. Johnson, V. Sherk, P.S. MacLean.
Univ. of Colorado Sch. of Med.
D250 I906.14 The Effect of Television Viewing and
Portion Size on Intake during a Meal. R. Rosenthal, H. Raynor.
Univ. of Tennessee, Knoxville.
OBESITY AND THE METABOLIC SYNDROME
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D251 II907.1
Cardiovascular and Lifestyle Factors
Influencing the Metabolic Syndrome in Overweight and
Obese Participants of a Randomised Clinical Trial. L.
Tapsell, A. Humphries, E. Neale, M. Batterham. Univ. of
Wollongong, Australia.
D252 I907.2
Groundsel Bush (Baccharis halimifolia)
Enhances Adipocyte Development and Attenuates Inflammation
in Adipocytes In Vitro. S.E. Fuller, A.L. Boudreau, J.M.
Stephens. Pennington Biomed. Res. Ctr., Baton Rouge.
D253 II907.3
Intaken CHO/Fiber as Diagnostic Tool
for Diet Quality and Prognostics of Insulin Resistance in FreeLiving Adults. C. Bernardino, J.E. Corrente, R.C. Burini.
Botucatu Med. Sch. and Inst. of Biochem.,São Paulo State
Univ.
D254 I907.4 Association between Obesity and
Amino Acids: A Metabolomics Approach. D. Marchioni, A.A.
Carioca, A.A. Miranda, A.M. Carvalho, J. Steluti, I.D. Cotrim,
A.M. Silva, R.M. Fisberg. Univ. of São Paulo and Fed. Univ. of
São Paulo.
D255 II907.5
Metabolic Risk Factor Prevalence in
Children Participating in a Family-Based Community Diabetes
Prevention Program. C. Ussery, S. Going, D. Roe, R. Kutob,
C. Stump, N. Merchant, M. Hingle. Univ. of Arizona.
D256 I907.6
Long-Term Exposure of Very High Fat
Diet on Energy Intake, Hormones, Cellularity and Morphology
of Tissues – A Male Rodent Study. S. Chakraborty, D. Adhikari,
T.R. Chakraborty. New York City Col. of Tech/CUNY, Cross
Island Res. and Diagnostic Lab., Mineola and Adelphi Univ.
D257 II907.7
Components of the Metabolic Syndrome
and Its Association with Nutritional Status of Vitamin D in
Children and Adolescents with Obesity. E. Romero-Velarde,
E. Casillas-Toral, S. Fonseca-Reyes, L.M. Aguirre-Salas.
Univ. of Guadalajara and “Dr. Juan I. Menchaca” Civil Hosp. of
Guadalajara, Mexico.
289
M
O
N
NUTRITIONMONDAY
D258 I907.8
The Impact of Supplementation with
Omega-3 Long-Chain Polyunsaturated Fatty Acids on the
Prevalence of Metabolic Syndrome in Obese Adolescents.
P. Inda-Icaza, M. Lopez-Alarcon, M.L. Barbosa-Cortez,
C. Marquez, A. Armenta-Alvarez, M.T. Bram-Falcon, M.
Mayorga-Ochoa. Univ. Anahuac, Mexico and Mexican Inst. of
Soc. Security, Mexico City.
D259 II907.9
Effects of Melatonin on Lipid Metabolism
and Circulating Irisin in Diet-Induced Obese Sprague-Dawley
Rats. P-C. Chiang, C-C. Lo, C-Y. Lin, Y-w. Chien. Taipei
Med. Univ.
D260 I907.10 Pterostilbene Inhibits Mitotic Clonal
Expansion and Subsequent Decreases Adipogenic Factors
in 3T3L1
Y-J. Seo. CHA Univ., South Korea.
D261 II907.11 Associations between the Intake of
Soups and Stews and Metabolic Syndrome in Korean Adults:
Korean National Health and Nutrition Examination Surveys
(KNHANES) 2013 Y.J. Bae. Shinhan Univ., South Korea.
D262 I907.12 Protective Effects of Dietary Walnuts
on High Fat-Induced Hepatic Steatosis, Oxidative Stress and
Apoptosis in Mice. Y. Choi, M.A. Abdelmegeed, B-J. Song.
NIAAA, NIH.
D263 II907.13 A Dietary Intervention of Fish Oil Can
Restore Metabolic Dysfunction and Improve Estrous Cycle
Irregularity in Obese C57BL/6 Female Mice. S.M. Godwin, L.
Beech, R. Buddington, M. van der Merwe. Univ. of Memphis
Sch. of Hlth. Studies.
D264 I907.14
Body Composition Changes in WeightStable Overweight and Obese Middle-Aged Adults Who
Performed Exercise Training for 36 Weeks Impact Indexes
of Cardio-metabolic Health. A. Amankwaah, J. Eun Kim, W.
Campbell. Purdue Univ.
D265 II907.15 Understanding Obesity through a
Big Data Analysis. C.Y. Jin, O. Yu. Univ. of Wonkwang and
Chonbuk Natl. Univ., South Korea.
D266 I907.16 Serum Advanced Glycation EndProducts (AGE) of Humans before and after Consumption of
an AGE-Rich Meal. H. Powers, A. Breunig, F. Verissimo, T.
Silvamen, A. Oliveira, M. de Oliveira, S. de Araujo Lima, M.
Maher. Univ. of Wisconsin-La Crosse.
D267 II907.17
Impact of Mitochondrial Free Fatty Acid
Overload on Hepatic Ureagenesis in Mice with Nonalcoholic
Steatohepatitis. S. Kalavalapalli, K.I. Abdo, Z.J. Murphy, J.C.
Fernandez, K. Cusi, N.E. Sunny. Univ. of Florida.
D268 I907.18 Relationship between Self-Reported
Hot Pepper Consumption and Body Weight Status among
Adults. C. Wang, L. Huang, C. Butler. Kentucky State Univ.
D269 II907.19
Acanthosis Nigricans: Relation to Risk
of Type 2 Diabetes and Cardiovascular Diseases among
Jamaican Adolescents. S.C. Barrett, F. Huffman, A. Campa,
P. Johnson, M. Magnus, D. Ragoobirsingh. Northern Illinois
Univ., Florida Intl. Univ. and Univ. of the West Indies, Jamaica.
D270 I907.20 Dietary Supplementation with Chia
(Salvia hispanica L.) Oil Reduces the Complications Caused
by High Fat Diet-Induced Obesity. M. Citelli, T. Fonte-Faria, S.
Vargas-Silva, C. Barja-Fidalgo. Rio de Janeiro State Univ.
D271 II907.21Dietary
Raspberries
Ameliorate
Metabolic Syndromes in Diet-Induced Obese Mice. M-J. Zhu,
Y. Kang, M. Paola González García, X. Liang, Y. Xue, H. Pan,
M. Du. Washington State Univ.
290
METABOLIC PHENOTYPING, METABOLOMICS
AND BIOMARKERS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D272 I908.1 Using Untargeted Metabolomics to
Elucidate Metabolic Changes in Murine Skin following Tomato
Supplementation. J.L. Cooperstone, M.D. Teegarden, M.J.
Cichon, K.A. Tober, T.M. Oberyszyn, S.J. Schwartz. The
Ohio State Univ.
1
D273 II908.2
H NMR-Based Metabolomics Reveals
Urinary Metabolome Modifications in Female Sprague-Dawley
Rats by Cranberry Procyanidins. H. Liu, F. Tayyari, Z. Su, L.
Gu. Univ. of Florida and Univ. of Georgia.
D274 I908.3
Plasma Metabolome Correlates with
Habitual Dietary Intakes among Chinese Adults. D. Yu, S.
Moore, C. Matthews, Y-B. Xiang, R. Li, X. Zhang, Y-T. Gao,
W. Zheng, X-O. Shu. Vanderbilt Univ. Sch. of Med., NCI, NIH.,
Shanghai Cancer Inst. and Tennessee Dept. of Hlth., Nashville.
D275 II908.4 Variation
of
Fasting
Plasma
Inflammatory Markers in Overweight and Obese Individuals.
E.G. Beals, E. Demmer, N. Rivera, T.S. Rogers, E. Gertz, M.
Van Loan, J.B. German, J.T. Smilowitz, A.M. Zivkovic. Univ.
of California, USDA and Foods for Hlth. Inst., Davis.
D276 I908.5
Long-Term Intermittent Leucine Pulses
during Continuous Feeding Impact the Plasma Metabolome
of Neonatal Pigs. A. Suryawan, C. Boutry, R. Manjarín, S.W.
El-Kadi, J. Steinhoff-Wagner, H. Nguyen, M.L. Fiorotto, T.A.
Davis. USDA and Baylor Col. of Med.
D277 II908.6
Determination of NAT2 Activity in the
U.S. Population by Use of Caffeine Metabolite Ratios in Spot
Urine Samples: NHANES 2009–2010
C-I. Pao, M.R.
Sternberg, M. Rybak, C.M. Pfeiffer. Ctrs. for Dis. Control
and Prevent.
PROTEIN AND AMINO ACID METABOLISM
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D278 I909.1
Dietary Glycomacropeptide Increases
Fat-Free Mass, Bone Mineral Content and Fatty Acid Oxidation
Compared with Casein in Female Mice. E.A. Sawin, B.M.
Stroup, S.G. Murali, D.M. Ney. Univ. of Wisconsin-Madison.
D279 II909.2 The Increase in Liver Polyamine
Concentration Contributes to the Tryptophan-Induced
Stimulation of Hepatic Protein Synthesis. F. Yoshizawa, S.
Koike, K. Sugahara. Fac. of Agr., Utsunomiya Univ., Japan
and Grad. Sch. of Agr. Sci., Tokyo Univ. of Agr. and Technol.
MONDAYNUTRITION
D280 I909.3 Novel Mechanism Responsible for
Regulation of Branched-Chain Alpha-Ketoacid Dehydrogenase
Kinase. Y. Shimomura, Y. Kondo, R. Ito, A. Tsuji, K. Shibata,
Y. Kitaura. Nagoya Univ. Grad. Sch. of Bioagr. Sci. and Univ.
of Shiga Prefect. Sch. of Human Cultures.
D281 II909.4 Whole Body Protein Turnover in
Overweight/Obese Adults in Response to Whole Grain and
Refined Grain Diets – A Randomized Control Trial. J.P. Kirwan,
A.B. Ross, E.L. Kullman, S.K. Malin, A. Scelsi, S. Kochhar,
J-P. Godin. Cleveland Clin., Chalmers Univ. of Technol.,
Gothenburg and Nestle Res. Ctr., Lausanne.
D282 I909.5
Dietary Protein Source at Breakfast
Influences Subsequent Learning and Memory Performance. K.
Du, M.J. Dailey, J.S. Rhodes, J.L. Beverly. Univ. of Illinois at
Urbana-Champaign and Univ. of North Carolina at Greensboro.
D283 II909.6
Dietary Carbohydrates but Not Proteins
Are the Main Nutritional Determinant of FGF21 Production
in Mice. T. Chalvon-Demersay, P.C. Even, D. Tomé, C.
Chaumontet, J. Piedcoq, C. Gaudichon, D. AzzoutMarniche. AgroParisTech, INRA, Univ. Paris Saclay.
D284 I909.7
Effect of β-Hydroxy β-Methylbutyric
Acid on Macrophage Polarization. W-C. Mu, R.W. Grant.
Purdue Univ.
D285 II909.8 Dietary
Creatine
Supplementation
Reduced the Proportion of Dietary Arginine Directed toward
Guanidinoacetic Acid Synthesis and Reduced the Demand
for Methionine-Derived Methyl Groups, but Did Not Enhance
Whole Body Protein Synthesis in Neonatal Piglets. O.C.
Dinesh, T. Kankayaliyan, M. Rademacher, C. Tomlinson, R.F.
Bertolo, J.A. Brunton. Mem. Univ. of Newfoundland, Canada,
Evonik Nutr. & Care GmbH, Hanau, Germany, Univ. of Toronto
and The Hosp. for Sick Children, Canada.
D286 I909.9
Protein Level in a Meal Influences Novel
Object Recognition in Exercise-Trained Rats. M. Fecych, C.
Murray, D. Oberlin, V. Porcelli, J. Starnes, J. Etnier, J.L.
Beverly. Univ. of North Carolina at Greensboro.
D287 II909.10
A Minimal Compartmental Model for the
Assessment of Net Whole Body Protein Breakdown, Using
a Pulse of Phenylalanine and Tyrosine Stable Isotopes in
Humans. A. Mason, M. Engelen, G. Toffolo, N. Deutz. Texas
A&M Univ. and Univ. of Padova.
D288 I909.11 Arginine or Guanidinoacetic Acid Can
Serve as Precursors for Creatine Synthesis in Parenteral
Nutrition, but Only with Excess Methionine to Facilitate
Transmethylation. S.D. Bray, A. Aljaroudi, O.C. Dinesh, T.
Kankayaliyan, J.A. Brunton, R.F. Bertolo. Mem. Univ. of
Newfoundland, Canada.
910. OBESITY: CHRONIC DISEASES
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D289 II910.1
Effect of Obesity on Liver Metabolic and
Morphological Profile in Zucker Rats. R. Hakkak, S. Korourian,
T. Evans, O. Pavliv, A. Harb, S. Melnyk. Univ. of Arkansas for
Med. Sci. and Arkansas Children’s Hosp. Res. Inst.
D290 I910.2
Effects of Obesity on Serum and Hepatic
Cations in Zucker Rat Model. R. Hakkak, S. Korourian, M.
Niedoba, A. Romani. Univ. of Arkansas for Med. Sci., Arkansas
Children’s Hosp. Res. Inst. and Case Western Reserve Univ.
D291 II910.3
The Association of Serum Biomarkers
of Types 2 Diabetes with BMI. L.L. Stephen, K. Marshall, M.
Damour, T. Race. Ampersand Biosci., Saranac Lake, NY.
D292 I910.4
Weight Gain with Metabolic Dysfunction
Is Associated with Obesity-Related Cancer. S. Chadid, M.R.
Singer, B.E. Kreger, L.L. Moore. Boston Univ. Sch. of Med.
D293 II910.5Associations
between
Dietary
Macronutrients, Glucose and Insulin Dynamics in Obese
Adolescents. E. Braun, K. Wagner, S. Armah, L. Smith, C.
Boushey, E. Delp, T. Hannon, N. Gletsu-Miller. Purdue Univ.,
Univ. of Iowa, Indiana Univ. Sch. of Med. and Univ. of Hawaii.
D294 I910.6
Hiperandrogenemia Is Highly Frequent
in Adolescent Girls Who Are Obese. M. Lopez-Alarcon, P.
Inda-Icaza, C. Márquez, A. Armenta-Alvarez, M.T. BramFalcon. Mexican Inst. of Soc. Security, Mexico City and Univ.
Anahuac, Mexico.
D295 II910.7
Is BMI a Risk Factor for Enteral NutritionRelated Complications? T. Tran, D.S. Seres, B. Lebwohl, M.
Burgermaster. Mailman Sch. of Publ. Hlth. and Columbia
Univ. Med. Ctr.
911. NUTRIENT-GENE INTERACTION: GENOMICS,
PROTEOMICS AND METABOLOMICS
Poster
Nutrient-Gene Interaction RIS
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D296 I911.1
Predictive Modeling of Child Obesity
According to Salt-Sensitive Genes and Sodium Intakes in
Korean Children: The 3 Year-Panel Study. J. Park, S. Bak, S.
Park, M. Lee. Res. Inst. of Obesity Sci., Seoul and Sungshin
Womens’ Univ., South Korea.
D297 II911.2 Untargeted
Metabolomic
Profiles,
Childhood Obesity, and Metabolic Risk in the ELEMENT
Cohort. J. LaBarre, W. Perng, A. Karnovsky, L. Tang, P.
Song, C.F. Burant, A. Cantoral, K.E. Peterson, M.M. TéllezRojo. Univ. of Michigan Sch. of Publ. Hlth., Univ. of Michigan
Med. Sch., Natl. Inst. of Publ. Hlth., Morelos, Mexico, Univ. of
Michigan and Harvard W.T. Chan Sch. of Publ. Hlth., Boston.
D298 I911.3 Implications
of
Taste
Receptor
Polymorphisms
in
Dietary
Interventions:
TAS2R38
Polymorphisms Associate with Changes in Vegetable Intake.
J.C. Schisler, L. Calancie, K. Lenhart, T. Keyserling, Z.
Gizlice, C. Patterson, A. Ammerman. Univ. of North Carolina
at Chapel Hill.
D299 II911.4
Validation of Fatty Acids Regulated
Genes in Adipocytes and Muscle Cells. Y. Li, T. Gonzalez, M.
Wang, E. Cheng. Texas A&M Univ.-Kingsville.
D300 I911.5
Variation in ALDH4A1, Proline Intake
and Plasma Proteins in a Population of Young Adults. J.
Jamnik, M.H. Kim, C. Borchers, A. El-Sohemy. Univ. of
Toronto and Univ. of Victoria, Canada.
291
M
O
N
NUTRITIONMONDAY
D301 II911.6
Untargeted Profiling of the Urinary
Metabolomes of Smokers and Nonsmokers after a Strawberry
Intervention. M.D. Teegarden, M.J. Cichon, J.L. Cooperstone,
J.H. Ahn-Jarvis, C.M. Weghorst, Y. Vodovotz, S.J. Schwartz.
Col. of Publ. Hlth., The Ohio State Univ.
D302 I911.7
MicroRNAs as a Novel Mechanism
by Which Eicosapentaenoic Acid Mediates Inflammation in
Diet-Induced Obesity. E. Yen, N. Wijayatunga, M. Pahlavani,
L. Ramalingam, K.R. Kottapalli, N.S. Kalupahana, P.
Gunaratne, K. Rajapakshe, C. Coarfa, S. Dharmawardhane,
N. Moustaid-Moussa. Texas Tech Univ., Univ. of Sri
Jayewardenepura and Univ. of Peradeniya, Sri Lanka, Univ.
of Houston, Baylor Col. of Med. and Univ. of Puerto Rico-Med.
Sci. Campus.
D311 II912.9
CpG Methylation Differences between
Neurons and Glia Are Highly Conserved from Mouse to
Human. N.J. Kessler, T.E. Van Baak, M.S. Baker, E. Laritsky,
C. Coarfa, R.A. Waterland. Baylor Col. of Med.
D312 I912.10 The Impact of Choline Oxidation
Pathway on Liver Methylation Potential. D.S. Lupu, L.D.
Orozco, Y. Wang, S.H. Zeisel. Univ. of North Carolina,
Kannapolis, UCLA and Shanghai Jiao Tong Univ. Sch. of Med.
D313 II912.11 Decreased Beige Adipocyte Number
and Mitochondrial Respiration Coincide with Reduced FGF21
Gene Expression in Sprague Dawley Rats Fed Prenatal Low
Protein and Postnatal High Fat Diets. K.J. Claycombe, E.E.
Vomhof-DeKrey, R. Garcia, W.T. Johnson, E. Uthus, J.N.
Roemmich. USDA, Grand Forks.
912. NUTRIENT-GENE INTERACTION: EPIGENETICS
913. CARIG: CAROTENOIDS AND HEALTH
Poster
Poster
Nutrient-Gene Interaction RIS
Exhibit Halls A-D
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
1:45 pm–2:45 pm (II)
D303 II912.1 Effects of Maternal Vitamin D
Deficiency on Fetal Epigenetic Reprogramming. J. Xue, F.Y.
Ideraabdullah. Univ. of North Carolina at Chapel Hill.
D304 I912.2
Spontaneous Preterm Delivery, Dietary
Choline Intake and DNA Hypomethylation of Tumor Related
Genes in Pregnant Women. X. Chen, G. Bai, T.O. Scholl.
Rowan Univ. Sch. of Osteo. Med., NJ and Univ. of Maryland
Sch. of Dent.
D305 II912.3
Long Chain Fatty Acid Receptor 4
Mediates EPA-miR30b Axis Activation for Promoting Brown
Adipogenesis. J. Kim, M. Okla, S.K. Natarajan, S. Chung.
Univ. of Nebraska - Lincoln.
D306 I912.4
Determining Effects of Maternal Methyl
Donor Nutrient Deficiency and DNA Sequence Differences on
Methylation Potential and Offspring Developmental Outcomes.
A. Pal, J. Oakes, M. Hariri, M. Elnagheeb, K. Clement,
F. Ideraabdullah. Univ. of North Carolina at Chapel Hill
and Kannapolis.
D307 II912.5
Walnut Substantially Alters the DNA
Methylation Profile in Colon Cancer Stem Cells. S.W. Choi, J.
Choi, J. Kim, Y. Kim, S. Friso. CHA Univ. and Ewha Womans
Univ., South Korea and Univ. of Verona Sch. of Med.
D308 I912.6 Iron
Supplementation
Reverses
Reduced Global Hydroxymethylcytosine Associated with
Chronic Alcohol Consumption in Rats. S.W. Choi, S.A.Tammen,
J.E. Park, S. Friso, J. Chung. CHA Univ., South Korea, Tufts
Univ. Friedman Sch. of Nutr. Sci. and Policy, Kyung Hee Univ.,
South Korea and Univ. of Verona Sch. of Med.
D309 II912.7 DNA Methylation and MicroRNA
Expression Are Altered by Choline Deficiency during Mouse
Brain Development. I. Trujillo, N. Surzenko, Y. Wang, S.H.
Zeisel. Univ. of North Carolina at Chapel Hill, Kannapolis and
Third Military Med. Univ., China.
D310 I912.8 Genes and Sequence Variants in
Weight Loss in Response to Diet and Exercise: Meta-analysis.
Y.P. Jung, B. Sanchez, R. Kreider. Texas A&M Univ.
292
D314 I913.1
Associations of Serum Carotenoids
with Metabolic-Related Diseases in Middle-Aged and Elderly
Adults: A Cross-Sectional and Follow-Up Study. Y-M. Chen, C.
Wang, Y. Cao, G-d. Chen, J. Liu, Z-q. Zhang, W-t. Cao, Y-y.
Zhu, Y-h. Liu, W-q. Wen-qi Shi. Sun Yat-sen Univ., China.
D315 II913.2
A Nano-emulsion of Lutein Is More
Effective Than Regular Lutein in Reducing Cholesterol-Induced
Liver Injury in Guinea Pigs. A.G. Murillo, G.H. Norris, D.M.
DiMarco, S. Hu, Y. Luo, C.N. Blesso, M-L. Fernandez. Univ.
of Connecticut.
D316 I913.3
Lutein Protects the Retinal Pigment
Epithelium against Hypoxic and Oxidative Stress: In Vitro
Studies. G. Allison, C. Draper, C. Soekamto, X. Gong, L.P.
Rubin. Paul L. Foster Sch. of Med., Texas Tech Univ. Hlth. Sci.
Ctr. El Paso.
D317 II913.4 The Effect of Carotenoids on
Transforming Growth Factor β1-Induced Fibrogenesis in LX-2
Cells, a Human Hepatic Stellate Cell Line. M. Bae, J-Y. Lee.
Univ. of Connecticut.
D318 I913.5
Tomato-Based Supplement Supports
Cardiovascular Health. K. Linnewiel Hermoni, I. Shefer, G.
Raz. Lycored, Orange, NJ and Yavne, Israel.
D319 II913.6
Serum Carotenoids, Retinol, and Retinyl
Esters in Midwestern Premenopausal Women. S.J. Mondloch,
N. Binkley, S. Arscott, S. Tanumihardjo. Univ. of WisconsinMadison and Standard Process Inc., Palmyra.
D320 I913.7
Relationship between Concentrations
of Lutein and StARD3 among Pediatric and Geriatric Human
Brain Tissue. E.J. Johnson, J. Tanprasertsuk, B. Li, P.S.
Bernstein, R. Vishwanathan, M.A. Johnson, L.W. Poon. Tufts
Univ.,Boston, Univ. of Utah Sch. of Med. and Univ. of Georgia.
D321 II913.8 Differential Expression of Genes
Involved in Inflammatory Immune Response and Protein
Ubiquitination in the Prefrontal Cortex of Rhesus Macaque
with High and Low Lutein Content. E.S. Mohn, J.W. Erdman;
Jr., M. Neuringer, M.J. Kuchan, E.J. Johnson. USDA at Tufts
Univ., Univ. of Illinois at Urbana-Champaign, Oregon Hlth. &
Sci. Univ. and Abbott Nutr., Columbus, OH.
MONDAYNUTRITION
914. CARIG: BIOFORTIFICATION OF STAPLE CROPS
WITH MICRONUTRIENTS
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D322 I914.1 Consuming
Iron-Biofortified
Pearl
Millet Improves Measures of Free-Living Physical Activity in
Indian School Children. S.V. Luna, B. Denvir, S.A. Udipi, P.S.
Ghugre, E.M. Przybyszewski, J.D. Haas. Cornell Univ., SNDT
Women’s Univ., Mumbai and Columbia Univ.
D323 II914.2
Acceptability of Iron-Biofortified Pearl
Millet among Young Children in Urban Slums of Mumbai, India.
S.L. Huey, S. Udipi, J.L. Finkelstein, P. Ghugre, J. Haas, V.
Thakker, A. Thorat, A. Salvi, A. Kurpad, S. Mehta. Cornell
Univ., SNDT Women’s Univ., Mumbai and St. John’s Res.
Inst., Bangalore.
D324 I914.3
Influence of Temperature and Humidity
on the Stability of Carotenoids in Biofortified Maize Genotypes.
D. Ortiz, T. Rocheford, M. Ferruzzi. Purdue Univ.
D325 II914.4
Native African Plant Materials Modify
In Vitro Bioaccessibility of Provitamin A Carotenoids from
Blended Cereal Products. H. Debelo, C. Ndiaye, M. Ferruzzi,
B. Hamaker. Purdue Univ.
D326 I914.5
Improvements in Electrophysiological
Measures of Brain Function during Memory Processing in
Rwandan Women Consuming Iron Biofortified Beans. M.J.
Wenger, S.E. Rhoten, S.P. Scott, L.E. Murray-Kolb, M.G.
Lung’aho, J-B. Gahutu, J.D. Haas. Univ. of Oklahoma, Penn
State, Intl. Ctr. of Trop. Agr., Rwanda, Univ. of Rwanda and
Cornell Univ.
D327 II914.6
Bioaccessibility and Cellular Uptake
of Carotenoids, Carotenoid Precursors and A-Tocopherol
in Biofortified Golden Potatoes (Solanum tuberosum) C.
Chitchumroonchokchai, G. Diretto, G. Giuliano, M.L.
Failla. The Ohio State Univ. and Italian Natl. Agcy. for New
Technols., Rome.
D328 I914.7
Impact of Processing on the Stability
and Bioaccessibility of Provitamin A Carotenoids in Biofortified
Cassava Roots (Manihot esculanta, Crantz) I. Aragon, D.
Dufour, A.F. Escobar, F. Calle, H. Ceballos, M.G. Ferruzzi.
Purdue Univ., CIAT, Palmira, Colombia and CIRAD,
Montpellier, France.
915. EXPERIMENTAL ANIMAL NUTRITION:
PRENATAL AND POSTNATAL NUTRITION AND
ANIMAL MODELS OF DISEASE
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D330 I915.2 Disruption of Mitochondrial Folate
Transporter Gene (Slc25A32) Induces Embryonic Lethality and
Neural Tube Defects in Mice. J. Kim. Univ. of Texas at Austin.
D331 II915.3
Maternal Consumption of a Diet Lacking
Omega-3 Fatty Acids during Development Alters Pup Behavior
and Brain Metabolism Later in Life. C. Jackson, M. Alhado, E.
Gonzales, J. Shumake, D. Barrett, F. Gonzalez-Lima, M.A.
Lane. Texas State Univ. and Univ. of Texas at Austin.
D332 I915.4
Maternal Dietary Intake of Different
Lipid Sources during Pregnancy and Lactation Predispose the
Offspring to Metabolic Changes and Altered Liver Mitochondrial
Bioenergetics in Adult Life. P.C. de Velasco, G. Chicaybam, D.
Ramos, R. dos Santos, T. El-Bacha, A. Galina, M. Tavaresdo-Carmo. Fed. Univ. of Rio de Janeiro.
D333 II915.5 Intrauterine
Nutrient
Restriction
Programs Impaired Endothelial Function Associated with
Functional Dysfunction in Circulating Endothelial Progenitor
Cells. V.A. Oliveira, S.D. Silva Junior, L.V. de Souza, T.
Fernandes, E.H. Akamine, M.H.C. Carvalho, E.M. Oliveira,
L.C. Michelini, M.P. Franco. Fed. Univ. of São Paulo and Univ.
of São Paulo.
D334 I915.6
Brain Development after Preterm Birth
Is Enanced by Including Phosphatidylserine in Formula:
Evidence from Preterm Pigs. R.K. Buddington, V.V. Chizhikov,
J.J. Sable, H.J. Sable, I.Y. Iskusnykh, E.Y. Steshina, Z.R.
Holloway, K.K. Buddington, Y. Lifshitz. Univ. of Memphis,
Univ. of Tennessee Hlth. Sci. Ctr., Christian Brothers Univ. and
Enzymotec Ltd., Israel.
D335 II915.7 Effects of Choline Deficiency on
Composition of Sow’s Milk. A.T. Mudd, S.K. Johnson, L.S.
Alexander, C.M. Getty, R.N. Dilger. Univ. of Illinois, Urbana.
D336 I915.8 Transgenerational Effects of High
Salt Diet during Gestation. M.A. Peres, I.B. Oliveira, L.N.S.
Furukawa, J. Heimann. Univ. of São Paulo Sch. of Med.
D337 II915.9
Newborn Cardiac Structural Alterations
in Response to Salt Restriction or Overload during Pregnancy.
P. Seravalli, B.C. Zago, I.B. Oliveira, M.M. Veras, J. Heimann.
Univ. of São Paulo Sch. of Med.
D338 I915.10
Dietary Alpha-Lipoic Acid Impacts Brain
Development of the Young Pig. A.T. Mudd, R. Waworuntu,
B.M. Berg, R.N. Dilger. Univ. of Illinois, Urbana and Mead
Johnson Nutr.
D339 II915.11
Supplementation with Choline Chloride
in a Liquid Rodent Diet: Recipe Development for Differing
Caloric Intake in a Fetal Alcohol Model. T.W. Jackson, L.G.
Canipe III, C.L. Cheatham. Univ. of North Carolina at Chapel
Hill, Kannapolis.
D340 I915.12
Prepregnancy Vitamin D Deficiency and
Placental Growth and Development in Mice. A.D. Gernand,
M.T. Cantorna, F.J. Diaz, L.M. Snyder, J.M. Hester, S.
Vasudevan, M.M. Kamat, T.L. Ott. Penn State.
D341 II915.13 Dietary Deprivation of Each Essential
Amino Acid Induces Differential Systemic Adaptive Responses
in Mice. S. Kamata, J. Yamamoto, K. Karube, R. Ohkubo,
T. Kasahara, I. Ishii. Grad. Sch. of Pharmaceut. Sci., Keio
Univ., Japan.
D342 I915.14
Efficacy of Lycopene to Improve Cardiac
Ionic Balance Disturbance in Mice Exposed to Atrazine. J. Li,
J. Lin, L. Qin, J. Xia, S. Zhu, Z. Du, Y. Zhang. Col. of Vet. Med.
and Sch. of Resources & Envrn., Northeast Agr. Univ., China.
D329 II915.1
Lean Body Mass Accretion Follows
a Dose-Response to Dietary Vitamin D in Female Weanling
Rats. M. Razaghi, M. Djekic.ivankovic, S. Agellon, P. Lavery,
H.A. Weiler. McGill Univ.
293
M
O
N
NUTRITIONMONDAY
D343 II915.15 A Comparison of Effects of Lard and
Hydrogenated Vegetable Shortening on the Development
of High-Fat Diet-Induced Obesity in Rats. R. Kubant, A.N.
Poon, D. Sanchez-Hernandez, A.F. Domenichiello, P.S.P.
Huot, E. Pannia, C.E. Cho, S. Hunschede, R.P. Bazinet, G.H.
Anderson. Univ. of Toronto.
D344 I915.16 Dietary Protein Bioavailability in
Bariatric Surgery Rat Models. O. Bruneau, J-B. Cavin, L.
Ribeiro-Parenti, N. Khodorova, D. Tomé, A. Bado, M. Le
Gall, C. Gaudichon. UMR914 and UMRS1149, Paris.
D345 II915.17 High-Fat Diet Exacerbates Bone
Loss in Mice Implanted with Low-Dose Slow-Release
Lipopolysaccharide Pellets. J.J. Cao, C-L. Shen. USDA,
Grand Forks and Texas Tech Univ. Hlth. Sci. Ctr.
D346 I915.18 Thymic Involution beyond WaterSoluble Silicon Consumption. V. Gordova, V. Sergeeva.
Chuvash State Univ., Russia.
D347 II915.19 High-Iron Intake Impairs Growth and
Causes Copper-Deficiency Anemia in Mice. J-H. Ha, C.
Doguer, J.F. Collins. Univ. of Florida.
D348 I915.20
Leucine Ameliorates Endotoxin-Induced
Alterations in Protein-Protein Interactions within mTORC1
Complex in Neonatal Piglets. A.D. Hernandez-Garcia,
A. Suryawan, H. Nguyen, D.A. Columbus, R. Manjarin,
R.A. Orellana, T.A. Davis. Baylor Col. of Med. and Texas
Children’s Hosp.
D349 II915.21 Decreased Muscle Health in Dietary
Antioxidant-Deficient Aged Mice. M. van Dijk, F. Dijk, K. van
Norren, R. Jaspers, A. van Helvoort, S. Verlaan, Y. Luiking.
Nutricia Res., Utrecht, Wageningen Univ., Netherlands and VU
Univ. Amsterdam.
D350 I915.22
FADS2
Overexpression
Promotes
Metabolic Syndrome in Mice: Influence of Maternal Dietary
Polyunsaturated Fatty Acid Composition. C.M. Whitaker, C.M.
Mulligan, A.J. Evans, L.C. Li Puma, A.J. Chicco. Colorado
State Univ.
D351 II915.23 Study of Hematopoiesis in Protein
Restriction: Characterization of Bone Marrow Stromal Cells.
E.W.B. Santos, C. Dias, G.B. Silva, D.C. Oliveira, J.S.O.
Beltran, A.B. Hastreiter, E.J. Paredes-Gamero, P.B. Borelli.
Univ. of São Paulo and Fed. Univ. of São Paulo, Brazil.
D352 I915.24
Intracerebroventricular Oxytocin Effects
on mRNA Abundance Differ in Adipose Tissue of Chicks from
Low and High Body Weight-Selected Lines. A. Koskinen, B.
McConn, G. Wang, P.B. Siegel, M.A. Cline, E.R. Gilbert.
Virginia Tech.
D353 II915.25
Alpha-Melanocyte Stimulating Hormone
Affects Adipose Tissue Physiology in Broiler Chicks. S.L. Shipp,
G. Wang, X. Fu, M. Cline, E. Gilbert. VPI and State Univ.
D354 I915.26 Central Injection of Neuropeptide Y
Affects Dietary Macronutrient Composition-Mediated Changes
in Broiler Adipose Tissue mRNA Abundance. C. Williams, G.
Wang, B. McConn, M. Cline, E. Gilbert. VPI and State Univ.
D355 II915.27 Increased Intracellular Calcium Is a
Mediator of Heat Stress-Induced Adipocyte Hypertrophy. K.M.
Ajuwon, H. Qu. Purdue Univ.
D356 I915.28 Effect of Dietary Protein Source and
Quantity on the Growth and Body Composition of Juvenile
Danio rerio M.B. Williams, L. Dennis, N. Miyasaki, R. Barry, M.
Powell, S. Watts, D. Smith. Univ. of Alabama at Birmingham.
D357 II915.29 Anthocyanins Improved Mitochondrial
Dysfunction in Mice of Non-alcoholic Fatty Liver Disease
Induced by High Fat Diet. W. Ling, T. Shen, X. Tang, X. Jiang.
Sch. of Publ. Hlth., Sun Yat-sen Univ., China.
294
D358 I915.30
Effects of Obesity and Soy Protein Diet
on Feed Intake and Serum Leptin Level in Female Zucker
Rats. R. Hakkak, A. Bell, S. Korourian. Univ. of Arkansas for
Med. Sci. and Arkansas Children’s Hosp. Res. Inst.
D359 II915.31
Time-Restricted Feeding of a High-Fat
Diet Reduces Adiposity and Inflammatory Cytokine Production
in Mice. S. Sundaram, L. Yan. USDA, Grand Forks.
D360 I915.32 Multiple Vitamins, Not GlutamineSupplemented Resuscitation Fluid Improves Intestinal Integrity
and Alters Systemic Inflammatory Mediators in Rats with
Trauma-Hemorrhagic Shock. Y.H. Lin, H-C. Lo, T-C. Su. Fu Jen
Catholic Univ. and Changhua Christian Hosp., Taiwan.
D361 II915.33 Overexpression of the Cannabinoid
Receptor CB1 in Mouse Astrocytes Related to Prolonged
Intake of Commercial Sweeteners. J.A. Estrada, Z. MoriyamaEstrada, S. Olin-Carbajal, L. Díaz-Casasola, I. Contreras.
Autonomous Univ. of Mexico State, Toluca.
D362 I915.34 Activation of Ubiquitin-Proteasome
System Components in Heat-Stressed Pig Skeletal Muscle.
L.D. Zhao, Z. Zhang, G. Xie, J.T. Selsby, L.H. Baumgard, R.P.
Rhoads. Virginia Tech and Iowa State Univ.
D363 II915.35 The Effect of Feeding Soy Protein
Isolate and/or Omega-3 Polyunsaturated Fatty Acids on the
Spleen of Female PCK Rats. L.B. Gibson, K. Maditz, V.A.
Benedito, J.C. Tou. West Virginia Univ.
D364 I915.36 The Effects of Glutamine- and n-3
Polyunsaturated Fatty Acids-Supplemented Resuscitation
Fluid on Circulating Cytokines and Neutrophil Activity in Rats
with Trauma-Hemorrhagic Shock. Y-C. Wu, H-C. Lo, F-H.
Huang. Fu Jen Catholic Univ., Taiwan and Children’s Hosp. of
China Med. Univ., Taichung.
D365 II915.37 The Effects of Dietary Macronutrient
Composition on Lipid Metabolism-Associated Factor Gene
Expression in the Adipose Tissue of Chickens Are Influenced
by 3 Hours of Fasting. G. Wang, B. McConn, M.A. Cline, E.R.
Gilbert. VPI and State Univ.
D366 I915.38
Prebiotics and β-Glucan Affect Jejunal
and Serum Alkaline Phosphatase Affinity in Weanling
Pigs. M-A.N. Hayhoe, T. Archbold, M.Z. Fan. Univ. of
Guelph, Canada.
D367 II915.39 Modulation of Ileal Starch Digestion
by Exogenous Fibres and Different Genotypes of Potato in
Growing Pigs Fed a High-Fat Basal Diet. Q. Wang, T. Archbold,
M-A.N. Hayhoe, X. Yang, A. Sullivan, B. Bizimungu, A.
Murphy, D.W. Ma, A.M. Duncan, J. Htoo, M.Z. Fan. Univ. of
Guelph, Canada, Agr. and Agri-Food Canada, Fredericton and
Evonik Industries, Germany.
D368 I915.40
Preliminary Evaluation on the Effects of
Feeds on the Somatic and Cardiac Parameters of Zebrafish
(Danio rerio) R.A. Vargas, I.C. Vásquez, J.A. Sánchez.
Pontificia Univ. Javeriana, Colombia.
D369 II915.41 Small Intestinal Co-perfusion of
Alanyl-Glutamine and Free Glutamine with fMLP Bacterial
Peptide Resulted in a Diminished Inflammatory Response
in Parenterally and Sow-Fed Neonatal Piglets. A.R. Trevors,
M.G. Nosworthy, R.F. Bertolo, J.A. Brunton. Mem. Univ. of
Newfoundland and Univ. of Manitoba.
D370 I915.42 Cat’s Choose 30% of Their Calories
as Protein Which Is Associated with Both Body Composition
and Circulating Metabolites. D.E. Jewell, J.C. Vondran, M.A.
Vanchina. Hill’s Pet Nutr. Inc., Topeka.
MONDAYNUTRITION
D371 II915.43 Dogs Choose 23% of Their Calories
as Protein Which Is Associated with Body Composition and
Circulating Metabolites. D.E. Jewell, J.C. Vondran, M.A.
Vanchina. Hill’s Pet Nutr., Topeka, KS.
D372 I915.44
High Maternal Vitamin D Status In Utero
through Weaning Beneficially Affects the Gut Microbiota-Bone
Axis in Obese Male Mice. C.R. Villa, E.M. Comelli, A. Taibi, J.
Chen, S. Sacco, W.E. Ward. Fac. of Med., Univ. of Toronto and
Fac. of Applied Hlth. Sci., Brock Univ., Canada.
916. NUTRITION IMMUNOLOGY:
NUTRITIONAL IMMUNOLOGY, INFECTION
AND INFLAMMATION
Poster
(Sponsored by: Nutritional Immunology and
Innflamation RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D373 II916.1
Obesity, Rather Than Fat Content of
Diet, Contributes to Reduced Influenza Vaccine Efficacy in
Mice Fed a High Fat Diet. D. Wu, L. Li, W. Guo, J. Wu, D.E.
Smith, S.N. Meydani. USDA at Tufts Univ.
D374 I916.2 Vitamin a Supplementation and
Lipopolysaccharide-Induced Inflammation in the Neonate—a
Pilot Study in C57BL/6 Mice. C-H. Wei, A.C. Ross. Penn State.
D375 II916.3 Synergistic Effects of Glutamine,
Citrulline, and Antioxidant Vitamin C and E on Modulating
Splenocytic Immune Responses in Rats with Intestinal
Ischemia and Reperfusion. H-C. Lo, Y-W. Chiu, C-H. Lee. Fu
Jen Catholic Univ., New Taipei City, Chi-Mei Med. Ctr., Tainan
and Children’s Hosp. of China Med. Univ., Taichung, Taiwan.
D376 I916.4
In Vitro Comparison of AntiiInflammatory
Activity of Green Tea Catechins. S. Fechtner, S. Ahmed.
Washington State Univ. Col. of Pharm.
D377 II916.5
Development and Validation of a FoodBased Inflammation Score. A.C. Holmes, R.M. Bostick.
Emory Univ. and Winship Cancer Inst.
D378 I916.6
In Vitro Antimalarial Activity of Microbial
Metabolites from Mango Tannins (Mangifera Indica L.) V.P.
Venancio, L.C. Abrão, H. Kim, S.T. Talcott, S.U. MertensTalcott. Texas A&M Univ.
D379 II916.7 The Relationship between Total
Parenteral Nutrition and Central Line-Associated Blood Stream
Infections. A.G. Fonseca, M. Burgermaster, E. Larson, D.S.
Seres. Melman Sch. of Publ. Hlth., Sch. of Nursing, Columbia
Univ. and Columbia Univ. Med. Ctr.
D380 I916.8
Cranberry and Recurrent Urinary Tract
Infections in Generally Healthy Women: A Systematic Review
and Meta-analysis of Randomized Clinical Trials. H. Kern, D.
Liska, M. Chung. Biofortis, Addison, IL and Tufts Univ., Boston.
D381 II916.9
High Caffeine Consumption and Its
Association with Lower Intakes of Antioxidant Micronutrients,
and with Higher Food Insecurity in People Living with HIV in
the Miami Adult Studies on HIV Cohort. V. Ramamoorthy, A.
Campa, M. Rubens, S. Sales, C. Fleetwood, T. Stewart, I.
Hatsu, F. George, H. Khan, J.P. Liuzzi, M. Baum. Florida Intl.
Univ., Louis A. Johnson VA Med. Ctr., Clarksburg, WV and The
Ohio State Univ.
D382 I916.10
Barriers to Nutritional Counseling by a
Registered Dietitian for People Living with HIV. C.D. Fleetwood,
A. Campa, S. Martinez, A. Charlesworth, G. Alvarado, K.
Dizon, T. Li, F.G. Huffman, M. Baum. Louis A. Johnson VA
Med. Ctr., WV and Florida Intl. Univ.
D383 II916.11
Anti-inflammatory Effect of Black Adzuki
Bean in High Fat Diet-Induced Obese Mice. J-S. Yook, M. Kim,
K-A. Kim, Y-S. Cha. Chonbuk Natl. Univ. and Songwon Univ.,
South Korea.
D384 I916.12 A Reduction of Myeloperoxidase and
Interleukin-10 Expressions in Mesenteric Lymph Nodes of
the Rats Fed a Cholic Acid-Supplemented Diet. G-H. Joe, S.
Hori, H. Shimizu, H. Hara, S. Ishizuka. Hokkaido Univ. and
Shimane Univ., Japan.
D385 II916.13Vitamin
D
Reduces
Hepcidin
Concentrations Independent of Inflammatory Cytokines in
Healthy Adults: A Pilot, Randomized, Double-Blind, PlaceboControlled Trial of High-Dose Vitamin D3 E. Smith, J. Alvarez,
M. Kearns, L. Hao, J. Sloan, R. Konrad, T. Ziegler, S.
Zughaier, V. Tangpricha. Emory Univ., Eli Lilly and Co. and
Atlanta VA Med. Ctr.
D386 I916.14
Dietary
Supplementation
with
Montmorency Tart Cherry Prevents the Alterations in Gut
Mucosal Immunity That Occurs with Ovarian Hormone
Deficiency. E.K. Crockett, J.L. Graef, P. Ouyang, S.L. Clarke,
U. DeSilva, E.A. Lucas, B.J. Smith. Oklahoma State Univ.
D387 II916.15 The Anti-inflammatory Effects of
Spirulina platensis Extract Are Mediated, in Part, through the
Induction of an Endotoxin Tolerance-Like Mechanism. T.X.
Pham, J-Y. Lee. Univ. of Connecticut.
D388 I916.16 No Differential Effect of Beverages
Sweetened with Fructose, High-Fructose Corn Syrup, or
Glucose on Systemic Inflammation in Healthy, Normal
Weight or Obese Individuals: A Randomized Controlled Trial.
J. Kuzma, G. Cromer, D. Hagman, K. Breymeyer, C. Roth,
K. Foster-Schubert, S. Holte, D. Weigle, M. Kratz. Fred
Hutchinson Cancer Res. Ctr., Seattle Children’s Hosp. and
Univ. of Washington.
D389 II916.17 Probiotics (Lactobacillus gasseri KS13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum
MM-2) and Health-Related Quality of Life in Individuals with
Seasonal Allergies. J.C. Dennis, T. Culpepper, C. Nieves; Jr.,
M. Ukhanova, V. Mai, M.C. Christman, B. Langkamp-Henken.
Univ. of Florida and MCC Stat. Consulting LLC, Gainesville.
D390 I916.18
Relationship between Vitamin D Status
and Plasma Aminothiol Redox in Critically Ill Children. J.A.
Alvarez, J.R. Grunwell, S.E. Gillespie, V. Tangpricha, K.
Hebbar. Emory Univ. Sch. of Med.
D391 II916.19Calcineurin
Inhibitor-Induced
Hyperkalemia and Salt-Sensitive Hypertension in Early
Post-kidney Transplant Period. E. Tantisattamo, A.
Chokechanachaisakul, S. Pitukweerakul, P. Ratanasrimetha,
P. Shrivastava, D. Samarapungavan. Oakland Univ. William
Beaumont Sch. of Med., Feinberg Sch. of Med., Northwestern
Univ., Presence Saint Francis Hosp., Evanston and Siriraj
Hosp., Mahidol Univ., Thailand.
D392 I916.20 Undernutrition, Nutrient Intake and
Acute Phase Response of Anemic Children. I.A. Agdeppa,
M.V. Capanzana, C.R. Magsadia. Food and Nutr. Res. Inst.,
Taguig, Philippines.
D393 II916.21 Effects of Calorie Restriction on
Microglial Activation in a Murine Model. U. Quijano, I.
Contreras, J.A. Estrada. Autonomous Univ. of State of
Mexico, Toluca.
295
M
O
N
NUTRITIONMONDAY
D394 I916.22 Changes in the Expression of Cell
Surface Markers in Spleen Leukocytes in a Murine Model of
Frequent Sucralose Intake. M. Sánchez Delgado, J.A. Estrada,
I. Contreras. Autonomous Univ. of State of Mexico, Toluca.
D395 II916.23
Prevalence of Staphylococcal Diarrhea
in Some Developing African Countries. G.P. Einstein, O.L.
Tulp, T.C. Oyesile, O.F. Obidi. Univ. of Sci. Arts & Technol.,
Montserrat and Univ. of Lagos, Nigeria.
D396 I916.24 Chronic Consumption of Non-caloric
Sweeteners in Carbonylated Protein Concentrations from Blood
Lymphocytes of CD1 Mice. B.E. Martinez, J.A.E. Herrera,
L.G. Iniesta, R.V. Ramos, A.L.G. López. Autonomous Univ. of
State of Mexico, Toluca.
D397 II916.25 Serum Retinol and Selenium Levels
Correlate Negatively with Hemolysis Markers in Sickle Cell
Disease Adult Patients. M. Citelli, E. Delesderrier, K. Cordovil,
J. Omena, C.C. Santos-Rodrigues. Rio de Janeiro State Univ.
917. VITMIN: WATER AND FAT SOLUBLE VITAMINS
AND CHRONIC DISEASE
Poster
(Sponsored by: Vitamins and Minerals RIS)
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D398 I917.1
Effect of Vitamin D Fortified Cheese
on Oral Glucose Tolerance in Individuals Exhibiting Marginal
Vitamin D Status and an Increased Risk for Developing Type
2 Diabetes: A Double-Blind, Randomized Placebo-Controlled
Clinical Trial. T.S. Moreira-Lucas, A.M. Duncan, R. RabasaLhoret, R. Vieth, A. Gibbs, A. Badawi, T.M.S. Wolever. Univ.
of Toronto, Univ. of Guelph, Canada, Clin. Res. Inst. of Montreal
and Publ. Hlth. Agcy. of Canada, Toronto.
D399 II917.2Correlation
between
Plasma
25-Hydroxyvitamin D and Fiber Composition of Skeletal Muscle
in Response to Dietary Vitamin D3 or 25-Hydroxyvitamin D3
supplementation. M.Y. Park, J. Kim, K-Y. Whang. Korea
Univ., Seoul.
D400 I917.3
Whole Egg Consumption Increases
Serum 25-Hydroxyvitamin D Concentrations in Rats with DSSInduced Colitis. S.K. Jones, M. Rowling, K. Schalinske. Iowa
State Univ.
D401 II917.4
The Effect of Vitamin D Supplementation
on Blood Lipids in Minorities with Type 2 Diabetes. J. Exebio,
S. Ajabshir, G. Zarini, F. Huffman. Florida Intl. Univ.
D402 I917.5
Quantitative Measurement of Plasma
and Urinary Excretion of 3-Hydroxyisovaleryl Carnitine by
UPLC-MS/MS. Z. Wang. Natl. Inst. for Nutr. and Hlth., Chinese
Ctr. for Dis. Control and Prevent., Beijing.
D403 II917.6
Association between Serum Levels of
25-Hydroxyvitamin and Triglycerides in Patients with Metabolic
Syndrome L.F.C. Pedrosa, H.T. Pereira, A.T.O. Cunha, S.L.
Aquino, S.C.V.C. Lima, A.P.T. Fayh, J.G. Lima, K.C.M. SenaEvangelista. Fed. Univ. of Rio Grande do Norte, Brazil.
D404 I917.7
Vitamin A Status Affects the Body
Mass Gain and Hepatic Gene Expression in Rats Fed a
High-Fat Diet. H. Kuang, Y. Li, J. Eastep, G. Chen. Univ. of
296
D405 II917.8
Whole Egg Consumption Attenuates
Vitamin D Insufficiency in Type 1 Diabetic Rats. C.J. Saande,
K.L. Schalinske, M.J. Rowling. Iowa State Univ.
D406 I917.9 Elevated Systolic Blood Pressure
Is Associated with Low Serum 25-Hydroxyvitamin D
Concentrations of Children in the United States: NHANES
2005-2006 C. Moore, Y. Liu. Texas Woman’s Univ. and Baylor
Col. of Med.
D407 II917.10
Upregulated 1,25-Dihydorxyvitamin D in
High Fat Diet-Induced Obesity Could Be Restored by Feeding
a Low Fat Diet. Y.S. Jung, D. Wu, D. Smith, S.N. Meydani, S.N.
Han. Seoul Natl. Univ. and USDA at Tufts Univ.
D408 I917.1125-Hydroxyvitamin
D3
and
1,25-Dihydroxyvitamin D3 Modulate the Expression of
Myosin Heavy Chain Isoforms in C2C12 Cells during Early
Differentiation Stage. M.Y. Park, J. Kim, K-Y. Whang. Korea
Univ., South Korea.
D409 II917.12 Homeostatic Model Assessment Index
1 and 2 Are Associated with Serum 25-Hydroxyvitamin D
among Haitians and African-Americans Living in South Florida.
S. Ajabshir, J. Exebio, G. Zarini, J. Voccaro, F. Huffman.
Florida Intl. Univ.
D410 I917.13
Vitamin D Attenuates MED28-Mediated
Cell Growth and Migration in Human Colon Cancer Cells. N-T.
Hsieh, C-Y. Huang, Y-T. Weng, M-F. Lee. China Med. Univ.
and Chang Jung Christian Univ., Taiwan.
D411 II917.14 Association of Vitamin D Status with
Dual Task Physical Performance in Older Adults. J. Lopez,
A. Campa, J.E. Lewis, F.G. Ercanli-Huffman, J.P. Liuzzi, T.
Li, A.H. Martinez, S.M. Ferris. Florida Intl. Univ. and Univ.
of Miami.
D412 I917.15
Effect of Age on Vitamin D in Serum of
Male Rhesus Monkeys. A.M. Preston, J. Rodriguez-Orengo,
S. Ayala-Torres. Univ. of Puerto Rico-Med. Sci. Campus.
D413 II917.16 Assessing Dietary Intake of Minerals
in the Form of Mineral Ratios May Be More Informative for
Evaluating Their Status Than by Their Individual Intake. O.J.
Kelly, J.C. Gilman, J.Z. Ilich. Abbott Nutr, Columbus, OH and
Florida State Univ.
D414 I917.17 Assessing Dietary Intake of Vitamins
in the Form of Vitamin Ratios May Be More Informative for
Evaluating Their Status Than by Their Individual Intake. O.J.
Kelly, J.C. Gilman, J.Z. Ilich. Abbott Nutr., Columbus and
Florida State Univ.
918. VITMIN: MICRONUTRIENT BIOAVAILABILITY
AND ANTIOXIDANT FUNCTION
Poster
Exhibit Halls A-D
1:45 pm–2:45 pm (II)
D415 II918.1
Absorption of Iron in Caco-2 Cells
Evaluated by Ferritin Upregulation from Five Dietary
Supplement Iron Sources. S. Morgan, J.W. Hartle. Albion, UT.
MONDAYNUTRITION
D416 I918.2
Vitamin E Pharmacokinetics in Swine
Show Low Bioavailability of all-rac α-Tocopheryl-Acetate. T.
van Kempen, C. de Bruijn, K. Monkerhey, S. de Smet, J.
Michiels, M. Traber, C. Lauridsen. Trouw Nutr., Netherlands,
North Carolina State Univ., Ghent Univ., Belgium, Oregon State
Univ. and Danish Inst. of Animal Sci., Tjele.
D417 II918.3 Metabolomic
Profile
of
Serum
25-Hydroxy-Vitamin D. S.M. Nelson, G.M. Anic, O.A.
Panagiotou, A. Mondul, S.J. Weinstein, D. Albanes. NCI,
NIH, Rockville, MD and Ann Arbor, MI.
D418 I918.4
Improved Bioavailability of Iron from
Amino Acid Chelates in Fully Differentiated Human Intestinal
Epithelial (Caco-2) Cells. C. Doguer, N. Shay, J.F. Collins.
Univ. of Florida and Oregon State Univ.
D419 II918.5 Evaluating the Effect of Seizure
Induction on Top of HFCD and/or Vitamin E Administration on
the Levels of Oxidative Stress Biomarkers in the Hippocampus.
Z.A. Hasan, K.H. Alzoubi. Arabian Gulf Univ. Col. of Med. and
Med. Sci., Bahrain and Jordan Univ. of Sci. and Technol, Fac.
of Pharm.
D420 I918.6
Bioaccessibility of Vitamin D from Bread
Fortified with UV-Treated Yeast Is Lower Than Bread Fortified
with Crystalline Vitamin D2 and Bovine Milk. T.E. Lipkie, M.
Ferruzzi, C.M. Weaver. Cargill Global Food Res., Minneapolis
and Purdue Univ.
D421 II918.7
Individual Amino Acids Differentially
Regulate Paracellular Calcium Flux across an Intestinal Cell
Model. M. MacArthur, P. Marszewski, C. Cummings, J.
McClung, R. Matheny, E. Gaffney-Stomberg. U.S. Army Res.
Inst. of Envrn. Med., Natick, MA.
D424 I919.3
Zip14 (Slc39A14) Is Critical to Modulate
Inflammatory Responses in Murine Skeletal Muscle. J. Kim,
T.B. Aydemir, R.J. Cousins. Univ. of Florida.
D425 II919.4
Circulating Levels of Small Nucleolar
RNAs Are Affected by Zinc Supplementation in Early Pubertal
Females. A. Grider, R.D. Lewis, E.M. Laing. Univ. of Georgia.
D426 I919.5 Zinc Supplementation, Beta Cell
Function, Insulin Secretion, and Insulin Resistance in Black
and White Female Adolescents. A.J. Lobene, J.M. Kindler,
N.K. Pollock, E.M. Laing, R.D. Lewis. Univ. of Georgia and
D427 II919.6
Zinc Supplementation and Antioxidant
Activity in Adult Women in Rural Southern Ethiopia. A. Bogale,
B.J. Stoecker. NBTY Inc., Central Islip, NY and Oklahoma
State Univ.
D428 I919.7
Plasma Metabolite Profiles in Ethiopian
Women following Zinc Supplementation. S. Barton-Wechsler,
L.L. Atwell, A. Bogale, J. Choi, Y. Nkrumah-Elie, B. Stoecker,
E. Ho. California State Univ., Chico, Oklahoma State Univ. and
Oregon State Univ.
D429 II919.8
Dual Action of Zinc in Bone and
Vascular Calcification. I-S. Kwun, M-Y. Shin. Andong Natl.
Univ., South Korea.
D430 I919.9
Comparison of Macro Mineral Contents
following Kind of Vegetables Produced in Korea. J.B. Hwang,
E-J. Park, S. Kim, D. Seo, Y. Choi, S-N. Kim, J-S. Nam, M-O.
Yang. Korea Food Res. Inst., Seongnam-si, Rural Develop.
Admin., Jeonju-si, Suwon Women’s Univ. and Wonkwang
Digital Univ., South Korea.
919. VITMIN: ZINC
Poster
Exhibit Halls A-D
M
O
N
1:45 pm–2:45 pm (II)
D422 I919.1
Acute Effects of Aerobic Exercise on
Zinc Status – a Systematic Review and Meta-Analysis. A.
Chu, P. Petocz, S. Samman. Univ. of Otago, New Zealand and
Macqurie Univ., Australia.
D423 II919.2 Zinc
Supplementation
Activates
Nfe2l2/ARE-MT2-Antioxidant Pathway in a Model of Diabetic
Nephropathy. G. Ding, M. Hao, P. Tian, Q. Tang, H. Zhao, Z.
Darzynkiewicz, N.R. Ferreri, S. Hao. Natl. Inst. for Nutr. and
Hlth., Beijing and New York Med. Col.
297
PATHOLOGYMONDAY
Pathology
920. CELL DEATH, TISSUE INJURY AND REPAIR
Poster
Exhibit Halls A-D
A193 920.1
Inter-competetion and Conversion among
TNF-α-Induced Signaling Complexes Determine the Outcomes
of TNF-α Signaling. Z-H. Yang, X-N. Wu, X. Wang, P. He, M.
Hong, J. Han. Sch. of Life Sci. and Sch. of Pharmaceut. Sci.,
Xiamen Univ., China.
A194 920.2
Cathepsin Localization and Activity on the
Intestinal Epithelial Barrier of Rats following Hemorrhagic
Shock and Reperfusion. A.S. Courelli, F. DeLano, G.W.
Schmid-Schonbein. UCSD.
A195 920.3
Rip3 Forms Different Complexes Leading to
Apoptosis or Necrosis. W. Li. Xiamen Univ., China.
A196 920.4
Cellular Stress Response 1 Regulates RNA
Splicing of Epidermal Growth Factor Receptor and PlateletDerived Growth Factor Receptor through Inactivation of
Splicing Factor 3
A3 J. Luo, Z-H. Zuo, Y.P. Yu. Univ.
of Pittsburgh.
A197 920.5
Induction
of
Anchorage
Independent
Growth and Angiogenesis by Tungsten Carbide-Cobalt
Nanoparticles. M. Ding, T.L. Barber, L. Bowman. NIOSH/
CDC, Morgantown, WV.
A198 920.6
Induction of AP-1-MAPKs Signaling by Copper
Oxide Nanoparticles. T.L. Barber, L. Bowman, M. Ding.
NIOSH/CDC, Morgantown, WV.
A199 920.7
Ppm1b Negatively Regulates Necroptosis
through Dephoshophorylating Ri. p3 W. Jianfeng, C. Wanze,
L. Yangxin, A. Tingting, H. Jiahuai. Xiamen Univ., China.
A200 920.8
Gingival Cell Smoke Exposure Disrupts
Skeletal Muscle Metabolic Function. S.G. Laub, O.J. Taylor,
P.R. Reynolds, B.T. Bikman. Brigham Young Univ.
A201 920.9
Inhibition of Polyamine Oxidase Reduces
Hyperoxia-Mediated Neurovascular Injury in Retina. P.
Narayanan, C. Patel, Z. Xu, E. Shosha, R.B. Caldwell.
A202 920.10 Cleavage of the Osmotic Stress-Related
Transcriptional Regulator NFAT5 Is Critical for Cardiac Injury in
Coxsackievirus B3-Induced Myocarditis. Y. Qiu, P.J. Hansen,
M. Zhang, D. Yang. Univ. of British Columbia and Ctr. for Heart
Lung Innovation, Vancouver.
A203 920.11 Immunohistochemical Detection of AutophagyRelated Proteins in Canine Appendicular Osteosarcoma. C.R.
Schott, G.A. Wood. Ontario Vet. Col., Guelph.
A204 920.12 LC3 Overexpression Perturbs Pancreatic
Acinar Cell Homeostasis and Alters Pancreatitis Responses.
O. Mareninova, W. Jia, J. Elperin, E. Lotshaw, M. Pimienta,
B. Reicher, I. Gukovsky, A. Gukovskaya. David Geffen Sch.
of Med. at UCLA and VA Greater Los Angeles Healthcare Syst.
A205 920.13 Functional Diversity of Novel Disease
Mutations in the Unfolded Protein Response Regulator, AT. F6
W-C. Chiang, P. Chan, J.H. Lin. UCSD.
298
921. MUCOSAL INFLAMMATION AND HOSTPATHOGEN INTERACTIONS
Poster
Exhibit Halls A-D
A206 921.1
In Vitro Therapeutic Index Application in
Highthroughput Screening of the Anti-inflammatory Effects
of Natural Products Evaluation in Different Cell Lines. E.A.
Mazzio, D. Bauer, E. Taka, K.F. Soliman. Col. of Pharm. &
Pharmaceut. Sci., Florida A&M Univ.
A207 921.2
Alveolar Lipid Accumulation in GMCSFRβ KO
Mice Involves Epithelial Steatosis as Well as Macrophage
Lipotoxicity and Is Not Associated with Altered Surfactant
Lipid Synthesis. D.J. Corkill, A.N. Hunt, M.J. Hinrichs, M.C.
Rebellato, P. Ryan, A. Scott, M.A. Sleeman, A.D. Postle.
MedImmune Ltd, Cambridge, U.K., Univ. of Southampton and
MedImmune, Gaithersburg, MD.
A208 921.3
Echinacea purpurea Down Regulates LPSInduced Expression of Pro-inflammatory and Angiogenic
Factors in an Ex Vivo Model of Equine Placentitis. C. Sloboda,
S. Chico, J. Gordon, S. Bailey, K.A. Zwetsloot, C. Mowa.
Appalachian State Univ. and North Carolina State Univ.
Vet. Sch.
A209 921.4
Stress and Inflammatory Markers: The Impact
on Military Physical Performance. H.C. Tingelstad, J. Martin,
V. Tang, L.G. Fillion, M. Spivock, F. Haman. Univ. of Ottawa
and Canadian Forces Moral and Welfare Svc., Ottawa, ON.
A210 921.5
The Attenuating Effects of 1,2,3,4,6 Penta-oGalloyl-β-D-Glucose on the Inflammatory Cytokines Release
from Activated BV-2 Microglial Cells. P. Mendonca, D. Bauer,
E. Taka, K.F. Soliman. Col. of Pharm. & Pharmaceut. Sci.,
Florida A&M Univ.
A211 921.6
Upregulation of Chemokine Ligands and
Receptors in the Spinal Cord of Type 2 Diabetic Monkeys. N.
Kiguchi, H. Ding, C.M. Peters, N.D. Kock, S. Kishioka, J.D.
Wagner, J.M. Cline, M-C. Ko. Wake Forest Sch. of Med. and
Wakayama Med. Univ., Japan.
A212 921.7
Moringa oleifera Whole Methanolic Leaf
Extract Attenuates Levels of Angiogenic Factors in the Cervix of
Preterm Labor Mice Models. M. Fitch, S. Ray, K.A. Zwetsloot,
C. Mowa. Appalachian State Univ.
A213 921.8
Whole Ethanolic Moringa oleifera Leaf
Extract Generates Kinetic Growth Curves of Escherichia
coli Comparable to Pharmaceuticals. B. Smith, T. Orders, J.
Tallapaneni, S. Nair, V. Ravi, J. Emrani, J. Idassi, J. King,
K.A. Zwetsloot, C. Mowa. Appalachian State Univ. and North
Carolina A & T State Univ.
A214 921.9
Effect of the Exposure to Progesterone
Analogues in the Proliferation and Production of TNF-Alpha
and IL-10 by Circulating Leukocytes. I. Contreras, F.G. OchoaArriaga, M.C. Erazo-Muñoz, M. Alvarado-Guadarrama,
J.A. Estrada. Fac. of Med., Autonomous Univ. of State of
Mexico, Toluca.
MONDAYPATHOLOGY
A215 921.10 Celiac
Disease:
Role
of
Intestinal
Compartments in the Mucosal Immune Response. G.
Iaquinto, V. Rotondi Aufiero, G. Iacomino, G. Mazzarella,
M. Schettino, A. Masucci. Santa Rita Hosp. and N. Taccone
Fndn., Atripalda, Inst. of Food Sci., CNR and San G. Moscati
Hosp., Avellino, Italy.
922. EPITHELIAL BARRIERS, CELL MIGRATION AND
TISSUE REPAIR
Poster
Exhibit Halls A-D
A216 922.1
CD36-Myeloperoxidase Connection and the
Activation of Intestinal Fibroblasts. M. Anderson-Thomas, A.
Nillas, T.A. Reaves. Med. Univ. of South Carolina.
A217 922.2
Reacquisition of E-Cadherin Expression in
Metastatic Signet Ring Cell Carcinoma: A Potential Anchor
for Metastatic Deposition. Y. Ma, G.P. Siegal, S. Wei. Univ. of
Alabama at Birmingham.
A218 922.3
Granzyme B Disrupts Epithelial Barrier
Function. S. Santacruz, L. Parkinson, D. Granville. Univ. of
British Columbia and St. Paul’s Hosp., Vancouver.
A219 922.4
Maturation of Intestinal Barrier Function by
Glial Cell Line-Derived Neurotrophic Factor Is Mediated by
Inactivation of p38 MAPK. M. Meir, S. Flemming, N. Burkard,
C-T. Germer, N. Schlegel. Uniklin. Wuerzburg, Germany.
A220 922.5
Upregulation of Matrix Degrading Enzymes
and Lubricin in the Pathogenesis of Joint Disease Requiring
Arthroplasty C. Wanderling, N. Emanuele, P. Carlsgaard, J.
Lilles, T. Schnettler, D. Syed, N. Guler, W. Hopkinson, D.
Hoppensteadt, J. Fareed. Loyola Univ. Med. Ctr.
A221 922.6
Wound Healing in a Model of Systemic Lupus
Erythematosus May Be Delayed by a Lack of Interleukin-2
K.M. Doersch, M.K. Newell-Rogers. Texas A&M Hlth. Sci. Ctr.
Col. of Med. and Baylor Scott and White.
923. EXTRACELLULAR MATRIX
Poster
Exhibit Halls A-D
A222 923.1
Soluble VE-Cadherin Contributes to Loss of VECadherin-Mediated Adhesion and Endothelial Barrier Function.
S. Flemming, N. Burkard, M. Renschler, F. Vielmuth, M. Meir,
M. Schick, C. Wunder, C-T. Germer, V. Spindler, J. Waschke,
N. Schegel. Univ. Hosp. Wuerzburg, Univ. of Michigan and
Univ. of Munich.
A223 923.2
The Roles of Matrix Metalloproteinases in
Anterior Regeneration in Aeolosoma viride T.L. Tseng. Natl.
Taiwan Univ.
A224 923.3
Extracellular
Matrix-Stiffness
Regulated
Cancer Cell (A549) Migration. B. Gweon, Z. Li, Y. Shin, H. Yoo,
J.H. Shin. Hanyang Univ. and KAIST, Daejeon, South Korea.
A225 923.4
Analysis of Forces Acting on the Equine
Navicular Bone in Normal and Dorsiflexed Positions. K.C. Ruff,
M.L. Osborn, E.W. Uhl. Univ. of Georgia.
924. LIVER PATHOBIOLOGY
Poster
Exhibit Halls A-D
A226 924.1
Increase in Therapeutic Effects and
Therapeutic Window of Hepatocyte Xenotransplantation in
Hemophilia B Mice with a Safe Pretreatment Strategy Coupled
with Genetically Engineered Donor Cells. Y-C. Hsu, S-J. Yang,
K-Y. Chen, C-W. Yeh, Y-J. Huang, I-S. Yu, Y-M. Wu, S-W.
Lin. Col. of Med., Natl. Taiwan Univ. and Natl. Taiwan Univ.
Hosp., Taipei.
A227 924.2
Inhibitory Effect of Luteolin on Hepatic Stellate
Cell Activation Is STAT3 Dependent. X. Wang, F.J. Bohanon,
O. Nunez Lopez, A.J. Kandathiparampil, J. Zhou, R.S.
Radhakrishnan. Univ. of Texas Med. Branch.
A228 924.3
Activation of Platelet-Derived Growth Factor
Receptor Alpha in Hepatic Stellate Cells during Chronic Liver
Injury. A. Kikuchi, S. Monga. Univ. of Pittsburgh Sch. of Med.
A229 924.4
DNA Damage Response Plays Critical Role
in Liver Regeneration after Acetaminophen Overdose. P.C.
Borude, B. Bhushan, U. Apte. Univ. of Kansas Med. Ctr.
A230 924.5
Role of Hepatocyte Nuclear Factor 4 Alpha in
Hepatocyte Regeneration. I. Huck, M.W. Manley; Jr., U. Apte.
A231 924.6
Complete Inhibition of Regeneration in Mice
following Simultaneous Elimination of MET-EGFR Signaling.
S. Paranjpe, W.C. Bowen, M. Haynes, T. Paranjpe, A. Orr, S.
Liu, G.C. Tseng, J. Luo, W. Mars, G.K. Michalopoulos. Univ.
of Pittsburgh.
A232 924.7
Loss of Wnt Secretion by Macrophages
Promote Heptobiliary Injury following DDC Diet. A. Jiang, H.
Okabe, M.E. Preziosi, M. Poddar, S.P. Monga, S. Nagarajan.
Univ. of Pittsburgh Sch. of Med., The Second Affil. Hosp., Sch.
of Med., Xi’an Jiaotong Univ., China.
A233 924.8
Glypican 3, CD81 and HCV E2 Protein Control
Yap and Hippo Pathway. Y. Xue, B. Bown, A. Orr, K. Koral, M.
Haynes, W. Mars, G. Michalopoulos. Univ. of Pittsburgh.
A234 924.9
Reprogramming Factor Oct4 Is Crucial for
Transdifferentiation of Hepatocytes to Biliary Epithelial Cells.
M. Doffou, G. Adams, G. Michalopoulos, V. Bhave. Georgia
Campus-Philadelphia Col. of Osteo. Med. Sch. of Pharm. and
Univ. of Pittssburgh Sch. of Med.
A235 924.10 VTL C3A Cells Secrete Factors Involved in
Coagulation Homeostasis. S.L. Riley, D.F. Mendez, P.W.
Bedard, L.K. Landeen. Vital Therapies Inc., San Diego.
A236 924.11 Neural Modulation of Liver Function to
Regulate Lipid and Glucose Metabolism. Y.A. Patel, R.J.
Butera. Georgia Tech.
A237 924.12 Aberrant Modulation of the BRCA1 and G1/S
Cell Cycle Pathways in Alcoholic Hepatitis Patients with Mallory
Denk Bodies Present Revealed by RNA Sequencing. H. Liu.
LA BioMed/Harbor UCLA Med. Ctr.
A238 924.13 Anti-fibrotic Effects of Synthetic TGF-β1/Smad
Oligodeoxynucleotide for the Simultaneous Regulation of
mRNA and Transcription Factor in Animal Model. K-K. Park,
J-Y. Kim, H-J. An, W-H. Kim, K-H. Kim. Sch. of Med., Catholic
Univ. of Daegu, South Korea.
299
M
O
N
PATHOLOGYMONDAY
A239 924.14 Insights into Translational Utility of Rodent
Models of Hepatic Fibrosis. C. Saravanan, J. Judge, Y. Song,
B. Dietrich, J. Wu, A. Bauer, K. Mansfield. Novartis Insts. for
Biomed. Res., Cambridge, MA, Shanghai and Basel.
925. PATHOBIOLOGY OF INFECTIOUS DISEASES
Poster
Exhibit Halls A-D
A240 925.1
Group a Streptococcus Persists in the
Lysosomes of Phagocytic Cells. K. Zheng, J. Snipper, H. No,
A. Till, C. Okumura. Occidental Col., CA and UCSD.
A241 925.2
Advancements in the Management of
Chromoblastomycosis among Immunocompromised Patients:
An Overview. T. Hinojosa, P.C.Q. Zancanaro, E. Ramos, L.
Saldivar, S.K. Tyring. Med. Sch., Univ. of Monterrey, Mexico,
Hosp. de Base, Brazil, Ctr. for Clin. Studies, Houston, Univ. of
Monterrey and Univ. of Texas Hlth. Sci. Ctr., Houston.
A242 925.3
Identification of Protein Kinase R and Tissue
Distribution in Channel Catfish. J. Ball, M. Vides, Y. Kobayashi.
Fort Hays State Univ., KS.
A243 925.4
Effects of Sub-inhibitory Concentrations
of Hydrogen Peroxide and Fluoride on the Innate Immune
Resistance of Streptococcus mutans S. Peacock, C. Okumura.
Occidental Col., CA.
A244 925.5
Sequence Variation in Hepatitis B Virus
Variants of Chronically Infected Saudi Patients and Their
Interaction with Host Genetic Factors. F.N. Almajhdi, A. AlQudari, H.M. Amer, A.A. Abdo. Col. of Sci. and Col. of Med.,
King Saud Univ.
A245 925.6
Group A Streptococcus Prevents the
Acidification of Phagolysosomes in Macrophages. H.
Franscioni, J. Snipper, H. No, C. Okumura. Occidental
Col., CA.
A246 925.7
Cellular and Proteomic Characterization of the
Innate Immune Response in Bat Stars (Patiria miniata) A.K.
Andrus, B.T. Livingston. California State Univ., Long Beach.
A247 925.8
Substitutions in the Proximity of the Active Site
of Peptidylarginine Deiminase from P. gingivalis – Is There a
Correlation with Enzyme Activity? G. Bereta, K. Gawron, K.
Łazarz-Bartyzel, M. Łazarz, K. Stożek, A. Naskalska, M.
Burmistrz, K. Pyrć, M. Chomyszyn-Gajewska, J. Potempa.
Jagiellonian Univ. Med. Col., Inst. of Dent. and Malopolska Ctr.
of Biotechnol., Poland and Univ. of Louisville Sch. of Dent.
A248 925.9
Group a Streptococcus Prevents Initiation of
the Oxidative Burst Response in Immune Cells. I. Yuen, M.
McLain, H. Franscioni, N. Etesami, C. Okumura. Occidental
Col., CA.
A249 925.10 Cloning, Identification and Characterization of
Two MyD88s during Anterior Regeneration in Aeolosoma viride
C.P. Chen. Natl. Taiwan Univ.
300
A250 925.11 Group
A
Streptococcus
Streptococcal
Collagen-Like Protein (Scl-1) Enhances Bacterial Resistance
to Neutrophil Serine Proteases. J. Kim, N. Etesami, S.
Dohrmann, V. Nizet, C. Okumura. Occidental Col., LA, UCSD
and UCSD Skaggs Sch. of Pharm.
A251 925.12 Activation of Dynamin-Related Protein
1 Contributes to Conversion of Cardiomyocytes into a
Proinflammatory Phenotype in Rat Model of Sepsis. W.
Jiang, A. Tao, T. Mele, R. Kao, C. Martin, T. Rui. The Affil.
People’s Hosp. of Jiangsu Univ., China, Lawson Hlth. Res.
Inst., London, Canada and Schulich Sch. of Med. and Dent.,
Western Univ., Canada.
A252 925.13 Effects of Repeated LPS Infusion on
Hematologic, Metabolic, and Intestinal Histology Parameters.
S.K. Kvidera, E.A. Horst, E.J. Laughlin, J. Mayorga, J.T.
Seibert, M. Abuajamieh, M. Al-Qaisi, S. Lei, A.F. Keating,
J.W. Ross, L.H. Baumgard. Iowa State Univ.
A253 925.14 Decade Long Study in HIV-1+ Puerto Ricans
Finds Reduction in Average Drug Resistance Per Individual,
Changes in Antiretroviral Medication Resistances and Shifts in
Mutations Expression. L. Cubano, M.L. Roger, L. Rishishwar,
L.C. Sepúlveda-Torres, E. Ríos-Olivares, I.K. Jordan,
N. Boukli. Univ. Central del Caribe and Univ. del Sagrado
Corazón, PR and Georgia Tech.
A254 925.15 Role of the Human Parainfluenza Virus Type
3 Fusion Machinery in Viral Growth in the Natural Host. S.
Jusino, L.M. Palermo, A. Moscona. Univ. of Puerto Rico at
Ponce and Weill Cornell Med. Col.
A255 925.16 Rift Valley Fever Virus Protein Detected
by Multiple Immunohistochemical Methods. M. Gamez, B.
Faburay, B.S. Drolet, W.C. Wilson, J.A. Richt, A.S. Davis, E.
Stietzle. Col. of Vet. Med., Kansas State Univ.
A256 925.17 Streptococcal Collagen-Like Protein 1 Protects
Group A Streptococcus from Innate Immune Defenses. R.
Whalen, S. Dohrmann, J. Shimamoto, N. Etesami, G. Martin,
V. Nizet, C. Okumura. Occidental Col., LA, UCSD and UCSD
Skaggs Sch. of Pharm.
A257 925.18 Enhancing Quantitative-PCR-Based Detection
of Pathogenic Enteric Viruses in Coastal Marine Environment
Using
Monolithic
Chromatographic
Supports.
M.N.
Balasubramanian, J. Goncalves, N. Rački, K. Kovač, M. Hren,
V. Turk, M. Ravnikar, I. Gutiérrez-Aguirre. Biosistemika Ltd.,
Ljubljiana, Natl. Inst. of Biol., Piran and Ljubljiana, Slovenia.
A258 925.19 Exhaled Breath Carbon Isotopes Are a Marker
for Inflammation in Neonates with a Chorioamnionitis Risk
Factor. D.E. Butz, D-A. Pillers. Univ. of Wisconsin-Madison
and Isomark LLC.
A259 925.20 Role of Cox Pathway in Human Monocytes and
Monocyte-Derived Dendritic Cells Infected by Trypanosoma
cruzi S.C.H. Lonien, R.C. de Freitas, H.T. Suzukawa, F.F.
dos Santos, M.I. Lovo-Martins, G.F. Silveira, P.F. Wowk,
J. Bordignon, P. Pinge-Filho. State Univ. of Londrina and
Oswaldo Cruz Fndn., Curitiba, Brazil.
MONDAYPHARMACOLOGY
Pharmacology
926.OPIOIDS
Poster
Exhibit Halls A-D
A1
926.1
Efficacy Related Modulation of Behavioral
Effects of Opioids during Chronic Buprenorphine Treatment
in Squirrel Monkeys. S.L. Withey, C.A. Paronis, J. Bergman.
Harvard Med. Sch., McLean Hosp., Belmont.
A2
926.2
A Centrally Active, Peripherally Available
Mixed Efficacy MOR/DOR Ligand That Displays Reduced
Development of Negative Side Effects. J. Anand, I. Dripps, B.
Boyer, H. Mosberg, E. Jutkiewicz. Univ. of Michigan.
A3
926.3
Abuse Liability and Anti-addiction Potential of
the Atypical Mu Opioid Receptor Agonist IBNtxA. T.M. Keck, V.
Verchio, C. Wu, G. Moura-Letts. Rowan Univ.
A4
926.4
Gαo Proteins Mediate the Antihyperalgesic and
Antidepressant-Like Effects, but Not the Convulsive Effects,
Produced by Delta Opioid Receptor Activation. I. Dripps, R.
Neubig, K. Rice, E. Jutkiewicz. Univ. of Michigan, Michigan
State Univ. and NIDA, NIH, Rockville, MD.
A5
926.5
Differential Role of G Protein Signaling
Regulator RGS7 on Rewarding Effects of Opioids and
Psychostimulants. L. Sutton, O. Ostrovskaya, M. Dao, R.
Smith, K. Martemyanov. The Scripps Res. Inst., Jupiter, FL.
A6
926.6
Environmental
Enrichment
Augments
Behavioral and Epigenetic Response to Heroin SelfAdministration. A.J. McFalls, C.G. Imperio, D.R. Masser,
G.V. Bixler, B.C. Wronowski, K.E. Vrana, P.S. Grigson, W.M.
Freeman. Penn State, Hershey, Robert Wood Johnson Med.
Sch., Univ. of Oklahoma Hlth. Sci. Ctr. and Penn State Col.
of Med.
A7
926.7
The Effect of Ventral Tegmental Area Rictor
Knockout on Susceptibility to Chronic Social Defeat Stress and
Stress-Induced Changes in Morphine Reward. S. Kaska, M.
Mazei-Robison. Michigan State Univ.
A8
926.8
Effect of Opioids on Integrity of White Matter.
N.L. Korneeva, R. Fan, L.M. Schrott, T. Arnold, D. Graham.
LSU Hlth. Sci. Ctr., Shreveport.
A10
927.2
Breaking the TRPV1-Calcineurin Interaction as
a Novel Means for Pain Control S. McAllister, V. Zambelli, E.
Gross. Stanford Univ. and Butantan Inst., São Paulo.
A11
927.3
A Novel Class of Potent, Allosteric TRPA1
Antagonists Reverse Hyperalgesia in Multiple Rat Models of
Neuropathic Pain. J.M. Herz, E. Kesicki, J. Tian, M.X. Zhu,
W.J. Thomsen. Algomedix, Inc. and Univ. of Texas Hlth. Sci.
Ctr. at Houston.
A12
927.4
Soluble Epoxide Hydrolase Inhibitors Are
Orally Available, Non-Opiate, Non-NSAID Analgesics Which
Block Neuropathic Pain Better Than Gabapentin or Pregabalin
without Reduction in Mobility or Cognition. B.D. Hammock,
K. Wagner, B. Inceoglu, A. Bettaieb, F. Haj. Univ. of
California, Davis.
A13
927.5
Antinociceptive Effects of Synthetic Tetracycline
Compound and Influence of Cx3cr1 in Inflammatory Pain.
J. Guindon, C. Bezboruah, H. Blanton, C. Sherfey, P.C.
Marquardt, J.M. Martinez, S.E. Bergeson. Texas Tech Univ.
Hlth. Sci. Ctr.
A14
927.6
Slick (Kcnt2) Sodium-Activated Potassium
Channels Limit Nociceptor Excitability and Pain. D.L.
Tomasello. SUNY Univ. at Buffalo.
A15
927.7
Novel Inhibitors of the Soluble Epoxide
Hydrolase Block Pain in Multiple Models. K. Wagner, K.S.S.
Lee, S.H. Hwang, B.D. Hammock. Univ. of California, Davis.
A16
927.8
Adelmidrol, a Palmitoylethanolamide Analogue,
as a New Pharmacological Treatment for the Management of
Inflammatory Pain. S. Cuzzocrea, D. Impellizzeri, R. Di Paola,
M. Cordaro, G. Casili, E. Esposito. Univ. of Messina.
A17
927.9
The 5-HT4 Receptor Agonists Prucalopride
and BIMU8 Suppress Abdominal Nociception in Animal Models.
O. Lyubashina, I. Busygina, I. Sivachenko, S. Panteleev.
Pavlov Inst. of Physiol., Russian Acad. of Sci. and Valdman
Inst. of Pharmacol., First Saint-Petersburg Pavlov State Med.
Univ., St. Petersburg.
A18
927.10 Systemic Effects of AT-121 as a Safe Analgesic
without Abuse Liability in Primates. H. Ding, N. Kiguchi, P.
Czoty, M. Nader, N. Zaveri, M-C. Ko. Wake Forest Sch. of
Med. and Astraea Therapeut. LLC, Mountain View.
A19
927.11 Peptidomimetics
Exhibiting
Mu
Opioid
Receptor Agonist/Delta Opioid Receptor Antagonist Activity as
Novel Pain Therapeutics. N. Griggs, A. Bender, C. Gao, J.
Anand, J. Traynor, H. Mosberg. Univ. of Michigan.
927. NOVEL PAIN THERAPEUTICS
Poster
Exhibit Halls A-D
A9
927.1
Antihyperalgesic
and
Antiallodynic
Effects
of
3a,4,5,9b-Tetrahydro-4-(1-Naphthalenyl)-3HCyclopentan[c]Quinoline-8-Sulfonamide in an Animal Model of
Neuroinflammatory Pain. M. Abbas, S. Rahman. South Dakota
State Univ.
301
M
O
N
PHARMACOLOGYMONDAY
928. EFFECTS OF PAIN ON OTHER MEASURES
Poster
Exhibit Halls A-D
A20
928.1
Neuropathic Pain Unmasks Delta Opioid
Receptor-Mediated Analgesia. E.W. Ong, S.V. Holdridge,
K.A. Sutherland, S.A. Armstrong, A.M.W. Taylor, L. Xue,
C.M. Cahill. Queen’s Univ., Canada, Univ. of California, Irvine
and UCLA.
A21
928.2
Controlling for Individual Differences in
Temperature Sensitivity Reduces Potency Differences among
Subjects in a Warm Water Tail Withdrawal Procedure in Rhesus
Monkeys. P.F. Weed, L.R. Gerak, D.R. Maguire, C.P. France.
Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
A22
928.3
Effects of MIA-Induced Osteoarthritis on Hind
Limb Weight Bearing and Bone Biology Endpoints in Rats with
or without Access to Running Wheels. K. Cone, R. Krivitsky,
E. Warner, I. Imbert, J. Allen, T. Henderson, C.J. Rosen,
E.J. Bilsky, T. King, G.W. Stevenson. Univ. of New England,
Maine Med. Ctr. Res. Inst. and Univ. of New England Col. of
Osteo. Med.
A23
928.4
Depression of Home Cage Wheel Running:
A Novel Method to Assess Spontaneous Migraine Pain. R.
Kandasamy, J.J. Calsbeek, M.M. Morgan. Washington State
Univ.
A24
928.5
Neuropathic Pain Alters Reward and Affect via
Kappa Opioid Receptor Upregulation. S. Liu, C. Cook, E. Thai,
S. Pickens, A.M. Taylor, V.D. Tea, F.I. Carroll, F.M. Leslie, C.J.
Evans, C.M. Cahill. Univ. of California, Irvine, UCLA and Res.
Triangle Inst., NC.
A25
928.6
Expression and Pharmacological Modulation
of Visceral Pain-Induced Conditioned Place Aversion in Mice.
S. AlSharari, D. Bagdas, P. Muldoon, I. Carroll, S. Negus, I.
Damaj. King Saud Univ., Virginia Commonwealth Univ., Uludag
Univ. Fac. of Med., Turkey and Res. Triangle Inst., Research
Triangle Park.
A26
928.7
Calorie Restriction Mimicking by Isoliquiritigenin
Attenuates Experimental Diabetic Neuropathy via Induction
of Mitochondrial Biogenesis and Autophagy. V.G. Yerra, A.K.
Kalvala, A. Kumar. Natl. Inst. of Pharmaceut. Educ. and Res.,
Hyderabad, India.
929.ANTIDEPRESSANTS
Poster
Exhibit Halls A-D
Neuropharmacology
A27
929.1
The Lysophosphatidic Acid LPA1 Receptor as
a Novel Molecular Target of Antidepressants in Neuronal Cells.
M.C. Olianas, S. Dedoni, P. Onali. Univ. of Cagliari, Italy.
A28
929.2
Citalopram’s Mechanism for Decreasing
Immobility Time in the Tail Suspension Test. R. Kingston, H.
Pan, A. Carneiro. Morehouse Col. and Vanderbilt Univ.
302
A29
929.3
Evaluation of Molecular Biomarkers in an
Adolescent Chronic Restraint Stress Model of Depression. M.
Graham, M. Hibicke, R. Hayslett. Mercer Univ. Col. of Pharm.
A30
929.4
Effects of Ketamine in the Forced Swim Test in
Female Rats. R. Felger, F. Carreno, A. Frazer. Trinity Univ., TX
and Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
A31
929.5
Ketamine Treatment Translocates Gsalpha
from Lipid Rafts in Cultured Glial Cells: Similar Effects to
Several Antidepressant Compounds. M.M. Rasenick, N. Wray,
J. Schappi. Univ. of Illinois Col. of Med. and Jesse Brown VA
Med. Ctr., Chicago.
A32
929.6
Chronic Isolation Stress Alters AntidepressantLike Behaviors in Animals Lacking RG. S4 J.N. Talbot, B.
Poncede Leon, C.L. Nielsen, C.M. Benhatzel, D. Alp, R.
Kirsh, J.R. Traynor. Touro Univ. Nevada, Roseman Univ. of
Hlth. Sci. Cols. of Pharm. and Med., Univ. of Michigan Med.
Sch. and Roseman Univ. of Hlth. Sci.
A33
929.7
Rapid Antidepressant-Like Effects of the
“Uptake-2” Blocker, Decynium 22 in the Flinders Sensitive Line
Rat Model of Depression. R. Fraser-Spears, W.A. Owens,
N.C. Mitchell, D. Overstreet, W. Koek, L.C. Daws. Univ. of
Texas Hlth. Sci. Ctr. at San Antonio and Univ. of North Carolina
at Chapel Hill.
A34
929.8
Adult Rats Exposed to Adolescent Chronic
Restraint Stress Display Robust Depressive-Like Behaviors
and Unexpected Responses to Desipramine and Fluoxetine. M.
Hibicke, M. Graham, R. Hayslett. Mercer Univ. Col. of Pharm.
A35
929.9
Beta-Arrestin1 and Testosterone Levels in
Women with Depression during Premenstrual Dysphoric
Disorder. K. Smith, F. Alam, T. Ansah, A. Archibong, T.
Nayyar. Meharry Med. Col.
930.SEROTONERGICS
Poster
Exhibit Halls A-D
Neuropharmacology
A36
930.1
Characterization of the Discriminative Stimulus
Effects of Lorcaserin in Rats. K.M. Serafine, C.P. France. Univ.
of Texas Hlth. Sci. Ctr. at San Antonio.
A37
930.2
Influence of Central Serotonin Availability on
Social and Repetitive Behavior in Mice. G.G. Gould, N. Witt,
J. Allen, A. Sanchez, M.A. Javors, L.C. Daws. Univ. of Texas
Hlth. Sci. Ctr. at San Antonio, Univ. of Texas San Antonio and
St. Mary’s Univ., TX.
A38
930.3
Psychedelics
Produce
Complex
and
Heterogeneous Transcriptional Responses in Diverse Cortical
Cell Types in the Brain of Rats as Determined by New Flow
Cytometric Methods Allowing for Sorting of Distinct Cell and
Neuronal Populations from Whole Brain. D. Martin, C. Porretta,
C.D. Nichols. LSU Hlth. Sci. Ctr., New Orleans.
A39
930.4
Lysergic Acid
Diethylamide
Modulates
Circadian Activity Behavior and the Expression Level of
Circadian Genes in Drosophila melanogaster in Both Sexes.
K.J. Sherman, C.D. Nichols. LSU Hlth. Sci. Ctr., New Orleans.
A40
930.5
Role of Serotonin 2A and 2C Receptors in
Ketamine-Induced Hypothermia. T.J. Murphy, K.S. Murnane.
Oglethorpe Univ. and Mercer Univ. Col. of Pharm.
MONDAYPHARMACOLOGY
931. MOLECULAR PHARMACOLOGY OF
HEPTAHELICAL RECEPTORS
Poster
Exhibit Halls A-D
A41
931.1
Structural Basis for Allosteric Coupling
between G Protein and the Agonist-Binding Pocket in GPCRs.
J. Mahoney, B. DeVree, G. Velez-Ruiz, S. Rasmussen, A.
Kuszak, E. Edwald, A. Manglik, M. Masureel, Y. Du, R. Matt,
E. Pardon, J. Steyaert, B. Kobilka, R. Sunahara. Univ. of
Michigan, Stanford Univ., Vrije Univ. Brussels and UCSD.
A42
931.2
A Panoramic Measure of Agonist, Modulator,
Receptor and Signaling Pathway Selectivity. R. Zhang, M.
Kavana. Merck Res. Labs.
A43
931.3
Estimation of Ligand Affinity for Receptor
States in Functional Studies on G Protein-Coupled Receptors.
F.J. Ehlert, R.S.L. Stein. Univ. of California, Irvine.
A44
931.4
Optimizing the Analysis of Bias to Produce
More Accurate Results. E. Stahl, F.J. Ehlert, L.M. Bohn.
Scripps Res. Inst., Jupiter, FL and Univ. of California, Irvine.
A45
931.5
Characterization of Novel Biased KOR
Agonist-Mediated Cell Signaling. J-H. Ho, K. Lovell, L. Zhou,
K. Frankowski, J. Aubé, L. Bohn. The Scripps Res. Inst.,
Jupiter, FL and Univ. of North Carolina at Chapel Hill.
A46
931.6
Multipronged
Approach
to
Investigate
the Mu-Delta Opioid Receptor Heteromer Interface. D.
Alongkronrusmee, H.T. Ghomi, S. Tang, M.A. Lill, R.M. van
Rijn. Purdue Univ.
A47
931.7
Efficacy at the Mu Opioid Receptor: Insights
from Orthosteric and Allosteric Ligands. K.E. Livingston, J.
Mahoney, A. Manglik, B. Kobilka, R. Sunahara, J.R. Traynor.
Univ. of Michigan, Stanford Univ. and UCSD.
A48
931.8
A Biased Mu-Opioid Receptor Positive
Allosteric Modulator That Does Not Alter Receptor Regulation.
K.E. Livingston, J.R. Traynor. Univ. of Michigan.
A49
931.9
Structurally
Diverse
Positive Allosteric
Modulators of the D1 Dopamine Receptor Potentiate G-Protein
and β-Arrestin-Mediated Signaling. K.D. Luderman, J.L.
Conroy, R.B. Free, N.T. Southall, M. Ferrer, J. Aubé, K.J.
Frankowski, D.R. Sibley. NINDS, NIH, NCATS, NIH, Rockville
and Univ. of North Carolina at Chapel Hill.
A50
931.10 Identification and Characterization of a Novel
Dopamine Receptor Antagonist with High Selectivity for the D2
Dopamine Receptor. R.B. Free, A.E. Dulcey, A.E. Moritz, T.B.
Doyle, J.A. Javitch, N.T. Southall, M. Ferrer, J.J. Marugan,
D.R. Sibley. NINDS, NIH, and NCATS, NIH, Rockville, MD and
Columbia Univ.
A51
931.11 Identification of a Novel Negative Allosteric
Modulator of the D3 Dopamine Receptor. A.E. Moritz, R.B.
Free, J.L. Conroy, E.S. Barnaeva, X. Hu, J.A. Javitch, N.T.
Southall, M. Ferrer, K.J. Frankowski, J. Aubé, D.R. Sibley.
NINDS, NIH, Bethesda, NCATS, NIH, Rockville, Columbia
Univ. and Univ. of North Carolina at Chapel Hill.
A52
931.12 LPA1 Receptor Antagonists Exhibit Signaling
Bias and Differential Efficacy in Models of Renal Fibrosis.
L.A. Hazelwood, L. Leys, G. Lundgaard, C.B. Putman, S.
McGaraughty, B. Clapham, D. DeGoey, L. Lee. AbbVie Inc.,
North Chicago.
A53
931.13 Structure-Activity Relationship of Peptide
Inhibitors of the Wnt/Frizzled Interaction. W.M. Blankesteijn,
K.C.M.
Hermans,
A.I.
Fernandez-Llamazares,
N.
Kriek, P. Timmerman. Maastricht Univ. and Pepscan
Therapeut. Netherlands.
A54
931.14 A Novel Activator of Canonical Wnt Signaling.
J. Baruah, K.K. Wary, R. Hitzman, J. Zhang. Univ. of Illinois
at Chicago.
932. NATURAL PRODUCTS – PHARMACOLOGY AND
TOXICOLOGY I
Poster
Exhibit Halls A-D
A55
932.1
Pharmacological
Properties
of
Chromobacterium violaceum Violacein at the Human Serotonin
2C Receptor. L. Fears, M. Curtis, T. Johnson, H. Fentress.
A56
932.2
Synthesis of Chitosan Nanoparticles of
Flavonoids Extracted from Black Bean (Phaseolus vulgaris L.)
Seed Coats to Enhance the Intestinal Absorption and Increase
Plasma Residence Time. C. Sanchez-Ramirez, R.A. ChavezSantoscoy, J.M. Cornejo-Bravo. Sch. of Chem. Sci. and
Engin., Autonomous Univ. of Baja California, Mexico.
A57
932.3
Semen Characteristics and Sperm Morphology
of Pistia stratiotes Linn. (Araceae) Protected Male Albino
Rats (Wistar Strain) Exposed to Sodium Arsenite. O.E. OlaDavies, O.S. Olawuwo, O.S. Ajani, O.M. Oyeyemi. Univ. of
Ibadan, Nigeria.
A58
932.4
Neuroprotective Activity of Macamides on
Manganese Chloride-Induced Toxicity in U-87 MG Glioblastoma
Cells. K. Gugnani, M. Bohlke, A. Pino-Figueroa. MCPHS
Univ., Boston.
A59
932.5
Induction of Nrf2 Activity by Ethyl Acetate
Extract of Lagenaria breviflora O.A. Oridupa, K.J. Ritchie.
Univ. of Ibadan, Nigeria and Liverpool John Moores Univ., U.K.
A60
932.6
Investigation of a Cyanobacterial Collection
from Curaçao for CNS Activity. E. Hilton, C. Staub, B. Kolber,
K. Tidgewell. Bayer Sch. of Nat. and Envrn. Sci., Grad. Sch. of
Pharmaceut. Sci. and Mylan Sch. of Pharm., Duquesne Univ.
A61
932.7
The
Marine
Pharmacology
and
Pharmaceuticals Pipeline in 2015 A.M. Mayer, M. Nguyen,
D.J. Newman, K.B. Glaser. Midwestern Univ., NCI at Frederick
and AbbVie Inc., North Chicago.
A62
932.8
Ameliorative Effect of Ethanol Leaf Extract
of Tridax procumbents L. (Asteraceae) on Sodium ArseniteInduced Toxicities in Male Wistar Rats. S.S. Ekundayo, O.A.
Odunola, O.E. Ola-Davies.
Univ. of Ibadan, Nigeria.
A63
932.9
The Hepatoprotective Effects of Whole Plant
Extracts of Ocimum basilicum in Experimentally Induced
Liver Damage in Rats. M.O. Abatan, M.T. Asala. Univ. of
Ibadan, Nigeria.
303
M
O
N
PHARMACOLOGYMONDAY
933. GENERAL TOXICOLOGY
Poster
Exhibit Halls A-D
Toxicology
A64
933.1
Management of Fluoride Toxicity on Adult Male
Wistar Rats’ Fecundity Using Some Selected Antioxidants. F.C.
Anacletus, B.M. Onyegeme-Okerenta, C.U. Iheka. Univ. of
PortHarcourt, Nigeria.
A65
933.2
Characterization of Nitrogen Mustard-Induced
Lung Injury Using Molecular Imaging Techniques. A. Venosa,
J. Schumacher, D. Adler, J. Laskin, E. Yurkow, A. Gow, D.
Laskin. Rutgers Univ., Piscataway.
A66
933.3
Passive Pulmonary Targeting: Preliminary
Assessment of the Effects of Microparticle Deposition in the
Lungs. K.A. Rivera, D. Gao, J. Holloway, S. Li, S.R. Johnson,
Z. Szekely, P.J. Sinko. Pharmaceut. Sci., Rutgers Univ.,
Piscataway and Pharmaceut. Sci., Piscataway.
A67
933.4
Altered Ion Transport in Normal Human
Bronchial Epithelial Cells following Exposure to Metal Welding
Particles. J.S. Fedan, J.A. Thompson, T.G. Meighan, P.C.
Erdely, J.M. Antonini. NIOSH, Morgantown, WV.
A68
933.5
Evaluation of the Effect of CdTe Quantum Dots
on Cell Viability. A. Rodríguez-Lopez, J. Reyes-Esparza, V.
Agarwal, L. Rodriguez-Fragoso. Autonomous Univ. of State
of Morelos, Cuernavaca.
A69
933.6
Evaluation of Analytical Parameters by
Mineralization by Dry Method for Lead Detection in Urine. J.A.
Giolo, G.S.C. Tiritan, F.T.A. Neves. Univ. of Sagrado Coracao,
São Paulo.
A70
933.7
Subacute Toxicity of Cadmium Sulfide
Quantum Dots Coated with Maltodextrin In Vivo. I. GutiérrezSancha, J. Reyes-Esparza, P. Rodríguez-Fragoso, L.
Rodriguez-Fragoso. Autonomous Univ. of State of Morelos,
Cuernavaca and CINVESTAV, Mexico City.
A71
933.8
Effect of Nimesulide on Blood Sugar Level
and Haematological Indices of Albino Rats. P.U. Agbasi,
L.C. Chukwu, P. Unekwe. Fed. Univ. of Technol., Owerri,
Chukwuemeka Odimuegwu Ojukwu Univ., Uli and Nnamdi
Azikiwe Univ., Awka, Nigeria.
A72
933.9
Evaluation of the Embryotoxic and Teratogenic
Effect of the β-HPC In Ovo B. Mendoza-Rivera, J. ReyesEsparza, R. de la Cruz-Cordero, L. Rodriguez-Fragoso.
Autonomous Univ. of State of Morelos and Nucitec S.A. de
C.V., Querétaro, Mexico.
A73
933.10 Pharmaceutical Waste Management in
Pharmacies in Zagreb. M. Bosnjak, I. Bosnjak, D. Drmic.
Univ. of Applied Hlth. Sci., Zagreb, Univ. of Mostar, Bosnia and
Herzegovina Sch. of Med., Univ. of Zagreb, Croatia.
304
934. PHASE I ENZYMES: CYTOCHROME
P450 ENZYMES
Poster
Exhibit Halls A-D
Drug Metabolism
A74
934.1
Cholesterol 7α-Hydroxylase (CYP7A1) Plays a
Critical Role in Preventing Hepatic Inflammation and Fibrosis.
H. Liu, J. Ferrell, S. Boehme, J. Chiang. Northeast Ohio
Med. Univ.
A75
934.2
Effect of CYP17A1 17,20 Lyase Inhibitors on
Regulation of Adrenal Androgen Biosynthesis. A.V. Pandey,
S.S. Udhane. Univ. of Bern.
A76
934.3
CYP26 Inhibition Increases Retinoic Acid
Concentrations in Target Tissues and Alters Retinoid Signaling.
F. Stevison, S. Tripathy, T. Kent, C.A. Hogarth, M.D. Griswold,
N. Isoherranen. Sch. of Pharm., Univ. of Washington and Sch.
of Molec. Biosci., Washington State Univ.
A77
934.4
Effect of Ethanol on the Metabolism of
Antiretroviral Drugs Elvitegravir and Darunavir in the Presence
and Absence of Their Pharmacoenhancers in Microsomes.
N.M. Midde, M.A. Rahman, C. Rathi, J. Li, B. Meibohm, W.
Li, S. Kumar. Univ. of Tennessee Hlth. Sci. Ctr., Memphis and
East China Univ. of Sci. and Technol., Shanghai.
A78
934.5
Inhibition of Human CYP3A-Catalyzed
Lithocholic Acid 3-Oxidation by Specific Vitamin E Isomers.
A.J. Lau, S.F. Chai, J.S.M. Teo. Yong Loo Lin Sch. of Med.,
Natl. Univ. of Singapore.
A79
934.6
Cinnamaldehyde Analogs
as
CYP2A6
Inhibitors: A Structure-Activity Study. S. Black, P. Joseph, A.
Higa, G. Moyeen, K. Ebisuya, M. Davis, J. Chan, J. Harrelson.
Pacific Univ., Hillsboro and Forest Grove, OR.
A80
934.7
Endogenous Substrates for Tumor-Specific
Human Cytochrome P450 CYP2W1 Y. Zhao, P. Ortiz de
Montellano. UCSF.
A81
934.8
Implications of In Vitro System Conditions for
CYP2C9 and CYP3A4: Impact of pH on Clearance and Enzyme
Inhibition. L.R.A. Rougee, M.A. Mohutsky, D.W. Bedwell, K.J.
Ruterbories, S.D. Hall. Eli Lilly and Co.
A82
934.9
Induction of CYP2A6 by Metronidazole in
Primary Human Hepatocytes. S. Stancil, C. Vyhlidal, G.
Kearns, S. Leeder, R.E. Pearce. Children’s Mercy Hosp. and
Univ. of Missouri-Kansas City and Arkansas Children’s Hosp.
Res. Inst., Little Rock.
A83
934.10 Mechanistic Role of Cytochrome P450
(CYP)1A2 in the Regulation of Hepatic and Pulmonary CYP1A1
Expression in Mice Treated with 3-Methycholanthrene. B.
Moorthy, P. Maturu, L. Wang, C. Chu, W. Jiang. Baylor Col.
of Med.
MONDAYPHARMACOLOGY
935.TRANSPORTERS
Poster
Exhibit Halls A-D
Drug Metabolism
A84
935.1
Chronopharmacology of Cisplatin: Role of the
Circadian Rhythm in Modulating the Cisplatin Transporters
Levels. D.N. Sorensen, P.P. Dakup, S. Gaddameedhi.
Washington State Univ.
A85
935.2
Activity of hBSEP Transporter Expressed
in Human and Insect Cells. S. Wright, M. Wilkerson, J. Li,
I. Hidalgo. Carson-Newman Col, TN and Absorption Systs.,
Exton, PA.
A86
935.3
Vorinostat Induces Blood-Brain Barrier
P-Glycoprotein Drug Efflux Activity: Implications for Limited
Brain Disposition of Co-administered Chemotherapeutics. R.K.
Sajja, T.R. Liles, S. Prasad, L. Cucullo. Texas Tech Univ. Hlth.
Sci. Ctr., Amarillo.
A87
935.4
Transport of Estrone Sulfate by Human
Placental Plasma Membrane Vesicles. T. Nanovskaya, S.
Patrikeeva, X. Wang, Q. Wang, M.S. Ahmed. Univ. of Texas
Med. Br.
A88
935.5
Establishing the Competitive Counterflow
Assay for OATP1B1 and OATP1 B3
M.
Katuwal,
R.
Schnegelberger, E. Wityk, M. Ruggiero, B. Hagenbuch.
A89
935.6
Organic Cation Transporters in Drug
Interactions with Methamphetamine and Metabolites. D.J.
Wagner, J. Wang. Univ. of Washington.
A90
935.7
Cerebroventricular Sodium, Regulated by
Na,K,ATPase and Endogenous Ouabain, Changes Neuronal
Excitability in a Rat Migraine Model. N.B. Gross, M.G.
Harrington. Huntington Med. Res. Insts., Pasadena.
A91
935.8
Identification of Novel Substrates and
Substrate-Dependent Interactions of Human Organic Cation
Transporter 1 K.H. Boxberger, B. Hagenbuch, J.N. Lampe.
A92
935.9
ATP-Binding Cassette Transporters and
Cytoprotective Genes Respond Differentially to a Hepatotoxic
Dose of Acetaminophen in Male and Female Mouse Brain.
K.M. Flores, J.L. Renfro, J. Manautou. Univ. of Connecticut.
A93
935.10 The N-Terminal Region of Organic Anion
Transporting Polypeptide 1B3 Plays an Essential Role in
Regulating Its Plasma Membrane Trafficking. S-E. Chun,
N. Thakkar, J.E. Park, S. Han, S.H. Maeng, Y-R. Lim, D.
Machado, W. Lee. Col. of Pharm., Seoul Natl. Univ., Univ. of
Kentucky and Konkuk Univ., South Korea.
A94
935.11 Buprenorphine,
Norbuprenorphine
and
Methadone Enantiomers Induce ABCB1/ P-gp and ABCG2/
BCRP Expression and Are Potent Aryl-Hydrocarbon Receptor
Agonists in Human Placental Cells. N.K. Neraudgomma, Q.
Mao. Univ. of Washington.
A95
935.12 Bioengineered
miR-1291
Prodrug
as
Sensitizing Agent for the Control of Pancreatic Carcinoma Cell
Proliferation and Tumor Growth. M. Tu, M. Li, A. Yu. UC Davis
Med. Ctr., Sacramento.
936. PRECLINICAL CANCER PHARMACOLOGY AND
CELL SIGNALING
Poster
Exhibit Halls A-D
Cancer Pharmacology
A96
936.1
Synergism between Bioengineered miR-34a
Prodrugand Doxorubicin in Suppressing Osteosarcoma cell
Proliferation and Xenograft Tumor Growth. M. Tu, Y. Zhao, Y.
Yu, W. Wang, Q. Chen, J. Qiu, A. Yu, A. Yu. Univ. of California
Davis, Sacramento, Wuhan Univ., China and Univ. of Buffalo.
A97
936.2
Tamoxifen Affects PLCg1 Expression in ER+
Breast Cancer Cells. R. Vergne, C. Ortiz, L. Godoy, J. Matta.
Univ. of Puerto Rico at Ponce and Ponce Hlth. Sci. Univ.
A98
936.3
Treatment of Triple Negative Breast CancerDerived Cells with Polyisoprenylated Cysteinyl Amide Inhibitors
Activates Caspase 3/7 and Disrupts F-Actin Organization
Leading to Apoptosis and Diminished Cell Motility. O. Salako,
R. Poku, A. Nkembo, F. Amissah, E. Ntantie, N. Lamango.
Florida A&M Univ. Col. of Pharm. & Pharmaceut. Sci.
A99
936.4
Small Molecule Inhibition of MEKK2 Signal
Transduction in Cancer Cells. J. Noll, J.E. Scott, B. Cuevas.
Loyola Stritch Sch. of Med., Maywood and North Carolina
Central Univ.
A100 936.5
A Dock-Derived PEDF Mimic Targeting Laminin
Receptor Downregulates VEGF Receptor. C.S. Umbaugh,
A. Diaz-Quiñones, M. Figueiredo. Purdue Univ. and Univ.
Central del Caribe Med. Sch., PR.
A101 936.6
miR-186 Suppresses Cell Proliferation and
Anchorage-Independence in a Metastatic Prostate Cancer Cell
Line. D.Z. Jones, M.L. Schmidt, K.R. Hobbing, G. Clark, L.R.
Kidd. Univ. of Louisville.
A102 936.7
In Vitro Basis for Cell Line-Dependent
Interaction between Sorafenib and Dasatinib in Human Nonsmall Cell Lung Carcinoma Cell Lines. Q. Zhou, R. Choksi,
X. Guo. Univ. of South Florida Col. of Pharm. and Univ. of
South Florida.
A103 936.8
Overexpression of ATP-Binding Cassette
Transporter ABCG2
Mediates Acquired
Resistance
LDC000067, a Selective Inhibitor of Cyclin-Dependent Kinase
CD. K9
M-L. Lin, C-P. Wu. Col. of Med., Chang Gung
Univ., Taiwan.
937. NOVEL THERAPEUTIC AGENTS IN CANCER
Poster
Exhibit Halls A-D
Cancer Pharmacology
A104 937.1
Novel ShetA2 Analog, SL-01-18, Triggers
Apoptosis and Targets Androgen Receptors in Human Prostate
Cancer Cells. V. Rajagopalan, T. Nguyen, G. Naizghi, S.
Liu. Touro Univ. California Col. of Pharm. and Safeway Inc.,
Milpitas, CA.
305
M
O
N
PHARMACOLOGYMONDAY
A105 937.2
Potent In Vitro and In Vivo Effects of EB-3D,
a Novel Choline-Kinase Inhibitor in Breast Cancer. G. Viola,
E. Mariotto, R. Bortolozzi, R. Ronca, L.C. Lopez Cara, A.
Entrena, G. Basso. Univ. of Padova and Univ. of Brescia, Italy
and Univ. of Granada, Spain.
A106 937.3
Inhibition of Tumor Growth in an Orthotopic
Model of Invasive Pancreatic Cancer: A Novel Molecular
Pathway Inhibitor. J. Cheng, K. Okolotowicz, A.M. Lowy,
M. Mercola, J. Cashman. Human BioMolec. Res. Inst. and
ChemRegen Inc., San Diego and UCSD and Sanford Burnham
Prebys Med. Disc. Inst., La Jolla.
A107 937.4
Evidence That Aspirin Blocks Platelet-Induced
Growth, Invasive Activity and Epithelial-MesenchymalTransition of Mouse Colon Cancer Cells. L.M. Lichtenberger,
D. Fang, E. Dial, K.V. Vijayan. Univ. of Texas Hlth. Sci. Ctr. at
Houston, Michael E. De BaBakey VA Med Ctr. and Baylor Col.
of Med.
A108 937.5
The Repurposing of Ritanserin for the Inhibition
of Diacylglycerol Kinase Alpha, a Novel Therapeutic Target in
Glioblastoma Multiforme. S. Boroda, T.E. Harris, B.W. Purow.
Univ. of Virginia.
A109 937.6
SAABFAT6-Induced Anti-growth and Survival
of A549 Adenocarcenoma Cell Is Mediated via Death and
Survival Pathways and Downstream Cascades Involving
Regulation of NF-κB Expression. S. Kwende, A.A. Oyagbemi,
O.A. Fagbohun, O.A. Fagbohun, O.T. Omobowale, A.A.
Adedapo, M.A. Yakubu. Texas So. Univ. and Univ. of
Ibadan, Nigeria.
A110 937.7
NOSH-Aspirin (NBS-1120) Inhibits Estrogen
Receptor Negative Breast Cancer In Vitro and In Vivo by
Modulating Redox-Sensitive Signaling Pathways. P.L.
Duvalsaint, M. Chattopadhyay, R. Kodela, K. Kashfi. CUNY
Med. Sch.
A111 937.8
Anti-cancer Effects of a Proposed Sigma-2
Receptor Agonist Structurally Similar to Tamoxifen. B.R.
Adams, C.R.T. Stang, L. Carlston, A.D. Faler, C.D. Thomas,
B.R. Schuler, A.M. Eichel, T.L. Whited, D.H. Kinder, R.A.
Schneider. Univ. of Findlay Col. of Pharm. and Ohio No. Univ.
Col. of Pharm.
A112 937.9
Identification and Evaluation In Silico and
In Vitro of Small Molecules in the KRas4B-PDEΔ Molecular
Complex in Pancreatic Cancer. D. Casique Aguirre, P.
García Gutiérrez, M.P. de León Bautista, M.Á. Vargas Mejía.
CINVESTAV and Autonomous Metro. Univ., Mexico City.
A113 937.10 Pre-clinical Development of rhTIMP-2 as a
Novel Anti-cancer Therapeutic. A. Chowdhury, B. Wei, Y.
Yamada, J.P. Schneider, W.G. Stetler-Stevenson. NCI, NIH,
Gaithersburg and Frederick, MD.
A114 937.11 Synthesis and Studies of N, N-(Dimethylamino)
Methylene Prodrugs of Gemcitabine, Ara-A and Ara-G. N.
Tawfeeq, S. Kerr. MCPHS Univ., Boston.
A115 937.12 Discovering Potent PTP4A3 Phosphatase
Small Molecule Inhibitors for Colorectal Cancer. K.E.
McQueeney, J.M. Salamoun, K. Handing, A. Boulton, E.R.
Sharlow, J.H. Bushweller, W. Minor, P. Wipf, J.S. Lazo. Univ.
of Virginia and Univ. of Pittsburgh.
306
938. PHARMACOLOGY TOOLS
Poster
Exhibit Halls A-D
Translational and Clinical Pharmacology
A116 938.1
Human Physiome on a Chip: Merging Tissue
Engineering and Systems Pharmacology. M. Cirit, L. Griffith,
D. Lauffenburger, S. Tannenbaum, C. Stokes, D. Trumper, D.
Hughes. MIT, Stokes Consulting, Redwood City, CA and CN
Bio Innovations, U.K.
A117 938.2
A Novel Neonatal Blood-Brain Barrier on a
Chip Closely Approximates the In Vivo Microenvironment. S.P.
Deosarkar, B. Prabhakarpandian, B. Wang, J. Sheffield, B.
Krynska, M. Kiani. Temple Univ., CFD Res. Corporation and
Widener Univ.
A118 938.3
Novel Long-Term Substance Delivery Method
in Chronic Dosing Studies. J. Rissanen, S. Ruohonen, H.
Jukarainen. Preclinapps Ltd., Finland.
A119 938.4
A Retrospective Study of Semen Quality in
Infertile Men with Varicoceles: Urological Expertise in Designing
and Conducting a Testicular Safety Evaluation Study. M. Yono,
Y. Inoue, K. Ito, M. Kimura, K. Furukawa, M. Hori, S. Tsuji,
T. Tanaka, Y. Sakata, S. Irie, J. Latifpour. Nishi-Kumamoto
Hosp., SOUSEIKAI, Japan, Osaka City Univ. Grad. Sch. of
Med. and Yale Univ. Sch. of Med.
A120 938.5
Substituted Thiadiazines as Potential Antistress Agents: Results of (Q)SAR Prediction and Experiments
In Vivo. A.P. Sarapultsev, P.A. Sarapultsev, L.P. Sidorova, V.V.
Poroikov, O.N. Chupakhin. Inst. of Immunol. and Physiol., Ural
Branch of RAS, Ural Fed. Univ. named after first President of
Russia B.N. Yeltsin, Inst. of Biomed. Chem., Moscow and I.Ya.
Postovsky Inst. of Organic Synthesis, Ekaterinburg, Russia.
A121 938.6
Preclinical Research Strategies for Newly
Approved Veterinary Drugs as Reflected in Early Publication
Patterns. U. Köster, I. Nolte, M.C. Michel. Univ. of Vet. Med.
Hanover and Johannes Gutenberg Univ., Mainz, Germany.
A122 938.7
Advances and Trend Analysis on Science
and Technology against Antibiotic-Resistant Bacteria through
Scientometric Approaches. E. Sohn. Korea Inst. of Sci. and
Technol. Info., Seoul.
A123 938.8
Real-Time,
Continuous
Electrochemical
Monitoring of Therapeutic Drugs In Vivo. P.A. Vieira, N.
Arroyo-Curras, K.L. Ploense, J. Somerson, K.W. Plaxco,
T.E. Kippin. Univ. of California, Santa Barbara.
A124 938.9
Cat-Exposure Results in Significantly More
Elicited Alarm Calls (22kHz Ultrasonic Vocalizations) Compared
to Snake-, Ferret-, or Sham-Exposure during a Rodent Model
of Traumatic Stress. C.M. Groeber Travis, R.F. Genovese.
Walter Reed Army Inst. of Res.
A125 938.10 Ex Vivo Response of Plasmodium falciparum
to Dihydroartemisinin in an Area of Ota Southwest Nigeria. T.M.
Dokunmu, A.E. Akinbohun, S.O. Rotimi, O.A. Rotimi, O.O.
Ogunlana. Covenant Univ., Nigeria.
A126 938.11 Perceived Social Support and Socioeconomic
Status Predict Maternal Delay Discounting Behavior and
Neural Function in Healthy Postpartum Women. L.K. Brents,
J. Young, B.T. Knight, J.L. Coker, S.L. Ray-Griffith, Z.N.
Stowe, G.A. James, C.D. Kilts. Univ. of Arkansas for Med. Sci.
MONDAYPHARMACOLOGY
939. CARDIOMYOCYTES/HEART FAILURE II
Poster
Exhibit Halls A-D
A127 939.1
Chronic Reduction of Heart Rate with
Ivabradine Does Not Alter the Extent of Myocardial Apoptosis
during Post-infarction Left Ventricular Remodeling in MiddleAged Rats. I. Kandinov, R.J. Tomanek, E.I. Dedkov. NYIT Col.
of Osteo. Med. and Univ. of Iowa Carver Col. of Med.
A128 939.2
Inhibiting Fibronectin Improves Cardiac
Function in a Mouse Model of Heart Failure. I. Valiente Alandi,
M. Nieman, J.D. Molkentin, B.C. Blaxall. Cincinnati Children’s
Hosp. Med. Ctr. and Univ. of Cincinnati.
A129 939.3
Contribution of NADPH Oxidase-Derived
Reactive
Oxygen
Species
to
Doxorubicin-Induced
Cardiomyopathy Mediated by Regulator of G Protein Signaling
6 B. Chakravarti, J. Yang, Z. Luo, K.E. Ahlers. Univ. of Iowa.
A130 939.4
Radiofrequency Renal Denervation Improves
Left Ventricular Function and Hemodynamics through
Modulation of Natriuretic Plasma Peptides in the Setting of
Heart Failure. D.J. Polhemus, J. Gao, A. Scarborough, R.
Trivedi, J. Bradley, T. Goodchild, F. Smart, D.R. Kapusta, D.
Lefer. LSU Hlth. Sci. Ctr., New Orleans.
A131 939.5
Kolaviron Attenuated Arsenic Acid-Induced
Cardiovascular Dysfunction by Enhancing Antioxidant Defense
System and Inhibiting Inflammatory and Apoptotic Signaling
Pathways. A.A. Oyagbemi, T.O. Omobowale, E.R. Olowu,
A.A. Adedapo, M.A. Yakubu. Univ. of Ibadan, Nigeria and
Texas So. Univ.
A132 939.6
Matrix Metalloproteinase-13 Inhibition Is
Protective in a Pressure Overload Model of Heart Failure. A.
Schafer, I. Valiente-Alandi, B.C. Blaxall. Cincinnati Children’s
Hosp. Med. Ctr. and Univ. of Cincinnati.
A133 939.7
Inhibition of COX-2/PGE2/EP4 Signaling
Protects against Post-hypoxic Apoptosis in H9C2
Cardiomyocytes. L. Pang, H. Ma, Y. Cai, M.G. Irwin, Z. Xia.
The First Hosp. of JiLin Univ., The Univ. of Hong Kong and Affil.
Hosp. of Guangdong Med. Col., China.
940. CHANNELS IN CARDIOVASCULAR
PHARMACOLOGY AND DISEASE
Poster
Exhibit Halls A-D
A134 940.1
T-Type Voltage-Gated Ca2+ Channels Do Not
Contribute to the Negative Feedback Regulation of Myogenic
Tone in Murine Superior Epigastric Arteries. B. Mullan, J.
Pettis, W.F. Jackson. Michigan State Univ.
A135 940.2
Resveratrol Can Enhance as Well as Relax
Contractions of the Rat Tail Artery: Possible Role of Endothelial
Potassium Channels. J.D. Peuler, S.M. Stom, L.E. Phelps.
Midwestern Univ., IL.
A136 940.3
Ontogeny Influences Pharmacological-Induced
L-Type Ca2+ Dependent Contractility of Pulmonary Arteries in
Sheep. C. Wolfe, A. Brunelle, L. Longo, S.M. Wilson. Loma
Linda Univ. Sch. of Med.
A137 940.4
Interaction of Gq- and Gs-Coupled Pathways in
the Regulation of Ca2+ Spiking and Activity of Kv7.5 Potassium
Channels in A7r5 Vascular Smooth Muscle Cells. C.R. Himes,
B. Condon, M. Rak, L.I. Brueggemann, K.L. Byron. Loyola
Univ. Chicago, Maywood.
A138 940.5
Decreased Role for BKCa Channels in
Endothelium-Dependent Relaxation of Nitrate Tolerant
Coronary Arteries. A. Mughal, M. Sane, C. Sun, S. O’Rourke.
North Dakota State Univ.
A139 940.6
Activation of CLC-3 Chloride Channels during
Myocardial Ischemia Limits Prolongation of Q-T and Effective
Refractory Period. Y. Yu, L.L. Ye, Y-G. Li, D.D. Duan. Shanghai
Jiaotong Univ. Sch. of Med. Xinhua Hosp. and Sch. of Med.,
Univ. of Nevada Reno.
A140 940.7
The Sarcoplasmic Reticulum Calcium ATPase:
A Target for Cardioprotective Drugs. J.A. Copello, Y.L. Darcy,
P.L. Diaz-Sylvester, M. Loulousis. So. Illinois Univ. Sch.
of Med.
941. BLOOD PRESSURE THERAPEUTICS
Poster
Exhibit Halls A-D
A141 941.1
Western Medicine versus Oriental Medicine in
Hypertension Therapy: Case Study. O.L. Tulp, T. Chow, C.M.
Konyk, G.P. Einstein. Univ. of Sci. Arts & Technol., Montserrat.
A142 941.2
ROMK Inhibitor Actions in the Nephron Probed
with Diuretics. S.V. Kharade, D. Flores, C. Lindsley, L. Satlin,
J.S. Denton. Vanderbilt Univ. Med. Ctr. and Icahn Sch. of Med.
at Mount Sinai.
A143 941.3
Evidences of Antihypertensive Potential of
Extract from Solanum capsicoides All. in Spontaneously
Hypertensive Rats. L.O. Simões, A.Q.G. da Silva, G.
Conceição-Filho, T. Ribeiro, R. Niero, V.C. Filho, D.F. Silva.
Fed. Univ. of Bahia and Univ. do Vale do Itajaí, Brazil.
A144 941.4
Carvacrol Inhibits TRPM7-Like Current in
Native Myocytes from Mesenteric Artery of Hypertensive Rats.
D.F. Silva, M.R. Reis, A.P. Vasconcelos, J.S. Cruz, D.A.M.
Araújo. Fed. Univ. of Bahia, Brazil, Georgia Regents Univ.,
Fed. Univ. of Paraíba and Fed. Univ. of Minas Gerais, Brazil.
A145 941.5
Administration of Omecamtiv Mecarbil Leads
to Hypotension and Diastolic Dysfunction in WKY Rat Model.
G.A. Fulop, L. Nagy, T. Csipo, A. Kovacs, B. Juhasz, D.
Priksz, S.L. Helgadottir, R. Porszasz, Z. Papp, A. Toth. Univ.
of Debrecen Fac. of Med., Hungary.
A146 941.6
Dopamine β-Hydroxylase Inhibitor Etamicastat
Prevents High Blood Pressure in Mice Lacking Salt-Inducible
Kinase 1 N. Pires, B. Igreja, E. Moura, M.J. Bonifácio,
P. Serrão, P. Soares-da-Silva. BIAL - Portela & Cª, S.A.,
Coronado, Univ. of Porto Fac. of Med. and MedInUP, Porto.
A147 941.7
Cardiovascular Effects Induced by Linalool
after Subchronic Treatment of Spontaneously Hypertensive
Rats. S.B. Camargo, L.O. Simões, C.F.dA. Medeiros, A.dM.
Jesus, J.dJ. Silva Júnior, J.B. Fregoneze, D.F. Silva. Inst. of
Hlth. Sci., Fed. Univ. of Bahia, Brazil.
307
M
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PHARMACOLOGYMONDAY
A148 941.8
The Effect of Adenosine A1-Receptor Agonists
on Regional Haemodynamics in Conscious Freely Moving
Rats. J. Woolard, A.J. Wheal. Univ. of Nottingham.
A149 941.9
Resveratrol Inhibition of Rac1-Derived
Reactive Oxygen Species by AMPK Decreases Blood
Pressure in a Fructose-Induced Rat Model of Hypertension.
P-W. Cheng, C-J. Tseng. Kaohsiung Veterans Gen. Hosp.,
Kaohsiung, Taiwan.
A150 941.10 Novel Antagonists of Transient Receptor
Potential-C6 Channels Prevent Inflammatory-Fibrotic Activation
of Cardiac Fibroblasts: Cardioprotective Therapeutics in
Pulmonary Hypertension. W.J. Thomsen, R.D. Brown, E.
Kesicki, K.R. Stenmark, J.M. Herz. Algomedix Inc., Mill Creek,
WA and Univ. of Colorado Denver, Aurora.
A151 941.11 Natriuretic Peptide Receptor-C Agonist
Attenuates the Enhanced Expression of Gqα, PLCβ1
Proteins and Vascular Smooth Muscle Cell Hypertrophy from
Spontaneously Hypertensive Rats: Role of ROS and ROSMediated Signaling. A. Jain, M.B. Anand-Srivastava. Univ.
of Montreal.
A152 941.12 Time to Blood Pressure Control According to
Drug Class in Patients with Hypertension. M.W. Johnson, R.
Sprissler, T.P. Olson, G.W. Beenken, E.M. Snyder. Univ. of
Minnesota, Minneapolis, Univ. of Arizona and Mayo Clin.
942. PATHOBIOLOGY OF BLOOD
PRESSURE CONTROL
Poster
Exhibit Halls A-D
A153 942.1
Multi-gene Pharmacogenetics and Blood
Pressure Control in Patients with Hypertension. M.W. Johnson,
R. Sprissler, T.P. Olson, G.W. Beenken, E.M. Snyder. Univ. of
Minnesota, Minneapolis, Univ. of Arizona and Mayo Clin.
A154 942.2
Hypertension
Mechanisms:
Elastin
Haploinsufficiency Alters Renal Structure and Function. P.
Osei-Owusu, E.A. Owens, L. Jie, B.A. Reyes, E.J. Van
Bockstaele. Drexel Univ.
A155 942.3
cFos Changes in the Hindbrain following
Central Microinjection of Nociceptin/Orphanin FQ in
Conscious Hypertensive Rats. C. Conner, B. Drzymala, L.
Koshy, L. Fortepiani, C. Franklin, H. Gottlieb. Univ. of the
Incarnate Word.
A156 942.4
Participation of TRPM4/TRPM7 Channels in
the Cardiac Activities of Carvacrol on Animals with Essential
Hypertension. Q.L. Alves, P.V. Santos, W.A. Santos, S.C.
Oliveira, R.L. Jesus, T.Q. Froes, M.S. Castilho, D.F. Silva.
Fed. Univ. of Bahia, Brazil.
A157 942.5
Pharmacological Evidence That NaHS
Inhibits the Vasopressor Responses Induced by Stimulation
of the Preganglionic Sympathetic Outflow in Pithed Rats. A.
Sanchez-Lopez, S. Huerta De La Cruz, E.J. Gutierrez-Lara,
J.H. Beltran-Ornelas, D. Centurion. CINVESTAV, Mexico City.
308
A158 942.6
Lipocalin-2 Deficiency Protects against
Aldosterone-Induced Hypertension and Organ Damages by
Inhibiting Mineralocorticoid Receptor Signaling. K. Yang, C.
Luo, B.M.Y. Cheung, M. Félétou, J-P. Vilaine, N. Villeneuve,
A. Xu, P.M. Vanhoutte, Y. Wang. Univ. of Hong Kong and Inst.
de Rech. Servier, Paris.
A159 942.7
Comparison of Outcomes between Normal and
Preeclamptic Pregnancies: A Prospective Study. R.R. Kalagiri,
S.H. Afroze, M. Reyes, N.N. Drever, S.R. Allen, M.R. Beeram,
V. Govande, D.C. Zawieja, T.J. Kuehl, M.N. Uddin. Baylor
Scott & White and Texas A&M Hlth. Sci. Ctr. Col. of Med.
A160 942.8
PDI via Nrf2 Contributes to the Regulation of
Renal AT1 Receptor Function and Blood Pressure. X. Wang,
M. Asghar. Col. of Pharm., Univ. of Houston.
A161 942.9
PRR Activates Canonical Wnt Signaling
Pathway during Pregnancy-Induced Hypertension in Rats. P.
Lopez, C. Ramirez-Montero, L. Anguiano-Robledo, M.A.
Avila-Ramirez, M.E. Hernandez-Campos. Sch. of Med., Natl.
Polytech Inst., Mexico City.
A162 942.10 Impaired Vascular Contractility to Uridine
Adenosine Tetraphosphate (Up4A) in Angiotensin II-Induced
Hypertensive Mice: The Receptor Desensitization? Z. Zhou,
V.R. Yadav, C. Sun, B. Teng, S.J. Mustafa. Karolinska Inst.,
Stockholm and West Virginia Univ.
A163 942.11 Toll-Like Receptor 9 Contributes to Increased
Vascular Tone via Small GTPase Activation. C.G. McCarthy,
C.F. Wenceslau, S. Ogbi, T. Szasz, R.C. Webb. Georgia
Regents Univ.
A164 942.12 Intermedin/Adrenomedullin 2 Is a Potent
Vasodilator
in
Chronic
Hypoxia-Induced
Pulmonary
Hypertensive Isolated Rat Lungs. G. Telli, H.B. Kandilci, B.C.
Tel, B. Gümüşel. Hacettepe Univ. Fac. of Pharm. and Ankara
Univ. Fac. of Med., Turkey.
A165 942.13 Effects of Nerve Stimulation in Mouse Lungs.
C. Kieffer, Y. Tu, P. Abel. Creighton Univ. Sch. of Med.
943. VASCULAR PHARMACOLOGY OF HEMOSTASIS
AND THROMBOSIS
Poster
Exhibit Halls A-D
A166 943.1
Activation of Apoptosis Signal-Regulating
Kinase 1 Occurs Downstream of PAR4 and TP-α Receptors
in Human Platelets. R.J. Derstine, M.U. Naik, R. Turaga, U.P.
Naik. Thomas Jefferson Univ.
A167 943.2
Nanogel Drug Carriers Presenting Platelet
GPIbα Mimic and Enhance Platelet Adhesion. J.W. Myerson,
I. Johnston, J. Wu, R. McClintock, Z. Ruggeri, M. Poncz, V.
Muzykantov. Univ. of Pennsylvania and The Scripps Res. Inst.
A168 943.3
3-O Sulfation of Heparin Is Required for
Hepatic Accumulation. E.N. Harris, J. Liu, C. Miller, Y. Xu, E.
Blank. Univ. of Nebraska-Lincoln and Univ. of North Carolina
at Chapel Hill.
A169 943.4
The First Intracellular Loop Regulates the
Platelet Thromboxane A2 Receptor-Gq-Dependent Signaling
and Function. Z.A. Karim, O. Lin, F.T. Khasawneh. Western
Univ. of Hlth. Sci., CA.
MONDAYPHARMACOLOGY/PHYSIOLOGY
A170 943.5
Identification of a Biased Agonist for P2Y2
Receptor to Suppress Pro-thrombotic Gene Expression
in Human Coronary Artery Endothelial Cells. L. Zhang.
Auburn Univ.
A171 943.6
Reducing Thrombosis Risk with JNK-2 siRNA
Therapeutic Nanoparticles in ApoE-/- Mice. H. Pan, R.U.
Palekar, J. Bacon, S. Allen, P.H. Schlesinger, S.A. Wickline.
Washington Univ. Sch. of Med. and Washington Univ. in
St. Louis.
A172 943.7
Distinct Vascular Effects of Celecoxib and
Rofecoxib In Vivo. E. Ricciotti, G.R. Grant, S-L. Liu, J.A.
Lawson, T. Grosser, G.A. FitzGerald. Univ. of Pennsylvania.
A173 943.8
Inhibition of vWF Secretion with Novel Gα12
N-Terminal α-SNAP Binding Domain Peptide Increases
Survival in Septic Mice. L. Rusu, J.W. Christman, X. Du, R.
Minshall. Univ. of Illinois at Chicago and The Ohio State Univ.
A174 943.9
Antibody Targeted against P2Y12 Receptor
Reduces Platelet Activity In Vitro and In Vivo. N.R. Hensch,
Z.A. Karim, F.T. Khasawneh. Western Univ. of Hlth. Sci., CA.
A175 943.10 Loss of Serotonin Transporter Function
Alters ADP-Mediated αIIbβ3 Activation through Disregulation
of 5Ht2A Receptor. K.H. Oliver, H. Hamm, A.M.D. Carneiro.
Vanderbilt Univ.
944. PHARMACOLOGY EDUCATION
Poster
Exhibit Halls A-D
Pharmacology Education
A176 944.1
Use of Web-Logs (Blogs) to Promote Student
Ownership. K.H. Oliver, D. Picard, J. Wikswo, C. Brame.
Vanderbilt Univ.
A177 944.2
Motivating Young Investigators to Pursue
Cancer Research Careers and Training. L.R. Kidd, D.W. Hein.
A178 944.3
Implementing Modified Active Learning
Strategies in Graduate Pharmacology Education. D.S.
Ponnoth. Arnold & Marie Schwartz Col. of Pharm., Long
Island Univ.
A179 944.4
Integrating
Pharmacokinetics,
Pharmacodynamics, and Pharmacogenetics into a FirstYear Medical School Foundational Module Using Active
Learning Methodologies. D.M. Peffley, J. Reuben, D. Wolff, C.
Farrell. Univ. of South Carolina Sch. of Med. Greenville and
Presbyterian Col. Sch. of Pharm., Clinton, SC.
A180 944.5
A Pilot Study: Influence of Free versus Cued
Recall Questions on Medical Student Utilization, Effectiveness,
and Perception of Pharmacology Educational Games. J.S.
Lee, M. Cowan, A.L. Gorman. Univ. of Central Florida Col.
of Med.
A181 944.6
Analysis of the Integration of Medical
Pharmacology Curricula across the Preclinical Continuum
Using Diverse and Innovative Approaches. A.L. Gorman. Univ.
of Central Florida Col. of Med.
A182 944.7
Digital Spaced-Learning Media: A Platform to
Reduce Student Anxiety and Promote Proficiency in Medical
Pharmacology Education. D. McHugh, T.M. Sherban, S.H.
Rahman. Quinnipiac Univ. Frank H. Netter MD Sch. of Med.
A183 944.8
Outcomes of a Dedicated Pharmacy Student
Summer Research Program. K. Brandl, D. Adler, C. Kelly, P.
Taylor, B. Best. Skaggs Sch. of Pharm. and Pharmaceut. Sci.
and Sch. of Med., UCSD.
Physiology
945. MICROCIRCULATION: VASOMOTOR CONTROL:
ENDOTHELIUM/SMOOTH MUSCLE/NERVES
Poster
Exhibit Halls A-D
B1
945.1
Capillary Response to Skeletal Muscle
Contraction: Implications for Redundancy in Microvascular
Blood Flow Control. I.R. Lamb, C.L. Murrant. Univ. of
Guelph, Canada.
B2
945.2
Attenuated Rapid-Onset Vasodilation with
Greater Force Production in Skeletal Muscle of Caveolin-2-/Mice. C. Fernando, Y. Liu, G. Sowa, S. Segal. Univ.
B3
945.3
Aging Impairs Spontaneous Ca2+ Signaling
and Regulation by CGRP in Smooth Muscle Cells of Mouse
Mesenteric Arteries. E.M. Boerman, S.S. Segal. Univ.
B4
945.4
Endothelial Conduction of Rapid Onset
Vasodilation in Mouse Skeletal Muscle. S.Y. Sinkler, S.S.
Segal. Univ. of Missouri-Columbia.
B5
945.5
Vascular Function Assessed by Passive Leg
Movement and Flow-Mediated Dilation: Evidence of Construct
Validity. M.J. Rossman, H.J. Groot, R.S. Garten, M. Witman,
R. Richardson. Univ. of Colorado Boulder, Univ. of Utah,
George E. Whalen VA Med. Ctr., Salt Lake City, Virginia
Commonwealth Univ. and Univ. of Delaware.
B6
945.6
Smooth Muscle/Endothelial KIR Channels
Modulate Cell-to-Cell Communication in Cerebral Arteries.
M. Sancho Gonzalez, N. Samson, B.O. Hald, A. Hashad, S.
Marrelli, S. Brett, D.G. Welsh. Western Ontario Univ., Univ. of
Calgary, Canada, Univ. of Copenhagen and Baylor Col. of Med.
B7
945.7
Role of Gamma-Adducin Gene in Cerebral
Vascular Myogenic Response. M. Pabbidi, Y. Ge, D.R. Harder,
R.J. Roman, F. Fan. Univ. of Mississippi Med. Ctr. and Med.
Col. of Wisconsin.
B8
945.8
Disruption in PKC-Mediated K Channel
Regulation Contributes to Enhanced Serotonin-Mediated
Carotid Vessel Constriction from the Fawn Hooded
Hypertensive Rat. G. Kaur, M. Pabbidi. Millsaps Col. and Univ.
of Mississippi Med. Ctr.
B9
945.9
Effect of Mantidis ootheca on the Mechanism
of Vasorelaxation in Thoracic Aorta. H.Y. Kim, Y.J. Lee, Y.M.
Ahn, R. Tan, J.H. Park, E.S. Choi, S.H. Lee, H.S. Lee, D.G.
Kang, H.S. Lee. Col. of Oriental Med. and Prof. Grad. Sch. of
Orienal Med., Wonkwang Univ., South Korea.
309
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PHYSIOLOGYMONDAY
B10
945.10 Distinct EC Coupling Mechanism Drives
Spatial Control of Vascular Tone in Cerebral Arteries. A.
Zechariah, B.O. Hald, N.G. Mazumdar, D.G. Welsh. Univ. of
Western Ontario and Univ. of Copenhagen.
B11
945.11 Evaluation of Smooth Muscle Cell Function
in Cultured Microvascular Networks. J.M. Motherwell, M.S.
Azimi, P.V.G. Katakam, W.L. Murfee. Tulane Univ.
B12
945.12 Angiotensin II Inhibits T-Type Ca2+ Channels
in Cerebral Arterial Smooth Muscle Cells. A.M. Hashad,
M. Sancho, D. Welsh. Univ. of Calgary and Univ. of
Western Ontario.
B13
945.13 Anti-vascular Inflammatory Effect of Samultang
in HUVECs. E.S. Choi, Y.J. Lee, J.J. Yoon, Y.M. Ahn, J.H.
Park, B.H. Han, S. Namgung, X-J. Jin, D.G. Kang, H.S. Lee.
Professional Grad. Sch. of Orienal Med., Wonkwang Univ.,
South Korea.
B14
945.14 Effect of Betulinic Acid on Diabetic
Atherosclerosis in Apolipoprotein-E Gene Knockout Mice. J.J.
Yoon, Y.J. Lee, B.H. Han, E.S. Choi, S. Namgung, R. Tan,
M.C. Kho, J.H. Park, D.G. Kang, H.S. Lee. Professional Grad.
Sch. of Oriental Med., Wonkwang Univ., South Korea.
B15
945.15 Effect of Hwangryunhaedoktang on TNFα-Induced Vascular Inflammation in Human Umbilical Vein
Endothelial Cells. B.H. Han, Y.J. Lee, J.J. Yoon, E.S. Choi, S.
Namgung, H.Y. Kim, Y.M. Ahn, X.J. Jin, H.S. Lee, D.G. Kang.
Professional Grad. Sch. of Orienal Med., Wonkwang Univ.,
South Korea.
B16
945.16 Purinergic Signaling in Rat Mesenteric Arteries
In Vivo. C. Aalkjaer, A. Mazur, V. Matchkov. Univ. of Aarhus,
Denmark and Copenhagen Univ.
B17
945.17 Propagation of Capillary-Initiated Conducted
Vasodilation in Skeletal Muscle – a Novel Paracrine Signaling
Pathway. N.M. Novielli, C.L. Murrant. Univ. of Guelph, Canada.
B18
945.18 Hyperpolarization of Mouse Pulmonary Artery
Smooth Muscle and Endothelium by Calcitonin Gene Related
Peptide. C. Norton, S. Segal. Univ. of Missouri-Columbia.
B19
945.19 H+ Induces Arteriolar Vasodilation but Does
Not Initiate a Conducted Response in Skeletal Muscle
Microvasculature. M.E. Charter, C.L. Murrant. Univ. of
Guelph, Canada.
946. MICROCIRCULATION: MICROVASCULAR FLOW
REGULATION/OXYGEN DELIVERY/NETWORKS
Poster
Exhibit Halls A-D
B20
946.1
PGC-1α Activation Confers Plasticity in the
Mediator of Dilation in Healthy and Diseased Human Arterioles.
J.C. Hockenberry, A.M. Beyer, D.D. Gutterman, A.O. Kadlec.
B21
946.2
Effects of Muscle Stretching on Skeletal
Muscle Microcirculation in Old Rats. K. Hotta, B.J. Behnke, P.
Ghosh, B. Chen, A. Churchill, M.L. Elam, S. Pourafshar, B.H.
Arjmandi, P. Maher, D. Kurien, R. Verma, D. Christou, J.M.
Muller-Delp. Florida State Univ. Col. of Med., Kansas State
Univ. Col. of Human Ecol., Florida State Univ. Col. of Human
Sci., Univ. of Florida Col. of Med., California State Polytech
Univ. Pomona, Col. of Agr. and Univ. of Florida Col. of Hlth. and
Human Performance.
310
B22
946.3
Endogenous Dipeptidyl-Peptidase IV Modulates
Skeletal Muscle Arteriolar Diameter in Rats. L.E. Neidert, M.
Al-Tarhuni, D. Goldman, H.A. Kluess, D.N. Jackson. Sch. of
Kinesiol., Auburn Univ. and Univ. of Western Ontario.
B23
946.4
Effect of Pulmonary Flow Heterogeneity and
Impaired Diffusing Capacity on Oxygen Uptake. T.K. Roy, T.W.
Secomb. Mayo Clin. and Univ. of Arizona.
B24
946.5
Comparison
of
Anterior
Tibial
Bone
Microvascular Flow, with Macrovascular Flow during Body Tilt.
R.L. Becker, J. Siamwala, B. Macias, A.R. Hargens. UCSD.
B25
946.6
Thermally Induced Erythrocyte Aggregation by
Surface Nanobubble Coalescence. H.S. Seidner, G. Gunter, S.
Weber-Fishkin, M.D. Frame. Stony Brook Univ.
B26
946.7
Band 3 and Glycophorin C as Potential Mediators
of Erythrocyte Aggregation during the Onset of Thermal Burn
Injury. H.S. Seidner, G. Gunter, S. Weber-Fishkin, M.D. Frame.
Stony Brook Univ.
B27
946.8
Rho-Kinase Inhibition Restores ATP Release
from Deoxygenated Red Blood Cells of Older Adult Humans.
M.L. Racine, M.J. Joyner, F.A. Dinenno. Colorado State Univ.
and Mayo Clin.
B28
946.9
Influence of Light Sources and Photoperiods on
Blood Physiological Variables Broilers Grown to Heavy Weights.
H.A. Olanrewaju, J.L. Purswell, S.D. Collier, S.L. Branton.
USDA, Starkville, MS.
B29
946.10 Sprague Dawley Severe Hemorrhagic Shock
Model Assessed by Systemic and Microcirculatory Parameters.
W.H. Nugent, B.K. Song. Song Biotechnols., Baltimore.
B30
946.11 Effects of Novel Oxygen Therapeutic on
Systemic and Microcirculatory Variables in Sprague-Dawley
Rat Isovolemic Hemodilution Model. B.K. Song, W.H. Nugent,
C.M. Sayes, E.D. Bruce. Song Biotechnols., Baltimore and
Baylor Univ.
B31
946.12 Renal Oxygenation and Microcirculation in
Relation to Fluid Therapy during Kidney Transplantation in
a Porcine Model. N. Moeslund, L.H. Nielsen, J.K. Eriksen.
Aarhus Univ., Denmark.
B32
946.13 Measurements of Blood Flow, Tissue Oxygen
Tension, and Oxygen Consumption in Rat Skeletal Muscle during
Recovery from Bouts of Brief, Transient Ischemia. S.C. Dodhy,
A.S. Golub, R.N. Pittman. Virginia Commonwealth Univ.
B33
946.14 A Dynamical Computational Model of Circulating
Blood Gases, Hemoglobin Binding, and pH Regulation in the
Microcirculation. J.B. Bassingthwaighte, R.K. Dash. Univ. of
Washington and Med. Col. of Wisconsin.
947.MICROCIRCULATION:
MICROVASCULAR MECHANICS/
HEMODYNAMICS/RHEOLOGY
Poster
Exhibit Halls A-D
B34
947.1
Rheological Property of Tapioca MaltodextrinBased Plasma Expander and Effect on Red Blood
Cells Morphology. S. Chatpun, K. Sawanyawisuth, K.
Piyachomkwan. Fac. of Med., Prince of Songkla Univ.,Fac.
of Med., Khon Kaen Univ. and Natl. Sci. and Technol. Develop.
Agcy., Thailand.
MONDAYPHYSIOLOGY
B35
947.2
Estimating Blood Flow in Skeletal Muscle
Arteriolar Trees Reconstructed from In Vivo Data. D. Goldman,
A.H. Saleem, B.K. Al-Khazraji, D.N. Jackson. Sch. of
Kinesiol., Univ. of Western Ontario.
B36
947.3
Erythrocyte Flux versus Flow in Microchannels
as a Function of Bifurcation Architecture and Re. S. Darvishi,
M. Frame. Stony Brook Univ.
B37
947.4
The Role of Calcium in Active Regulation of
Erythrocyte Deformability. O. Yalcin, B. Eglenen, M. Turkay, G.
Yavas, E. Ugurel, P. Connes. Sch. of Med., Koc Univ., Turkey
and Claude Bernard Univ. Lyon 1, France.
B38
947.5
Intermittent
Parathyroid
Hormone
Administration and Aortic Stiffness in Young and Old Fischer-344
Rats. R. Prisby, J. Guers, J. Kim. Univ. of Delaware.
B39
947.6
Systemic and Microcirculatory Effects of
Severe Hemorrhage and Resuscitation Using a Pegylated
Carboxyhemoglobin. B.K. Song, W.H. Nugent. Song
Biotechnols., Baltimore.
B40
947.7
Geometric and Topological Analysis of
Arteriolar Networks in the Rat Gluteus Maximus Muscle: One
Network to Rule Them All? M. Al Tarhuni, D. Goldman, D.N.
Jackson. Univ. of Western Ontario.
B41
947.8
Acute Reduction of Ambient Air Pressure
Enhances Arterial Vasodilation in Murine Resistance Arteries
Independently of Endothelial Factors. A. Shahid, J.S. Morton,
S.T. Davidge, M.S. McMurtry. Univ. of Alberta.
B42
947.9
Comprehensive Hemodynamic Analysis of
Arteriolar Networks in the Rat Gluteus Maximus Muscle. M. Al
Tarhuni, D.N. Jackson, D. Goldman. Univ. of Western Ontario.
948.MICROCIRCULATION:
MICROVASCULAR PATHOPHYSIOLOGYPHARMACOLOGY, THERAPEUTICS AND
TRANSLATIONAL ASPECTS
Poster
Exhibit Halls A-D
B43
948.1
A Role for Sarcolemmal Membrane-Associated
Protein in Mediating Autophagy in Endothelial Cells through
an AMPK-Dependent Mechanism. A.P. Lakshmanan, S.M.
Samuel, C. Triggle, B.S. Tuana, H. Ding. Weill Cornell Med.
Col. in Qatar and Univ. of Ottawa.
B44
948.2
Metformin Sensitizes Glucose Starved
Microvascular Endothelial Cells to Death by Inhibition of the
mTOR Pathway and Autophagy. S.M. Samuel, S. Ghosh, C.R.
Triggle. Weill Cornell Med.-Qatar, Doha.
B45
948.3
Inhibition of TRPC3 Channels Underlies
Hypoxia/Reoxygenation-Induced Endothelial KCa Channel
Dysfunction. X-C. Wang, J-H. Huang, W-T. Sun, C-M. Yu, G-W.
He, Q. Yang. The Chinese Univ. of Hong Kong and TEDA Intl.
Cardiovasc. Hosp., Tianjin, China.
B46
948.4
Flavonoid: Quercetin, a Multifunctional
Therapeutic Agent to Reverse Acute Crisis in a Transgenic
Sickle Mouse Model. S. Thangaswamy, H.H. Billett, C.A.
Branch, S.M. Suzuka, S.A. Acharya. Albert Einstein Col.
of Med.
B47
948.5
Global Cerebrovascular Dysfunction in the
Metabolic Syndrome following Ischemic Stroke. K. Branyan,
S. Brooks, E. DeVallance, S. Asano, J. Frisbee, P. Chantler.
West Virginia Univ.
B48
948.6
Microvascular Function Is Impaired in Adults
Who Reported Adverse Childhood Events. P. Rodriguez
Miguelez, J. Thomas, N. Seigler, J.S. Pollock, R.A. Harris.
Georgia Regents Univ. and Sch. of Med., Univ. of Alabama
at Birmingham.
B49
948.7
Response of Skeletal Muscle Arterioles In
Vivo to Modulation of Endothelial Glycocalyx by Resuscitation
Fluids after Hemorrhagic Shock. L. Torres, C. Salgado, J.
Sondeen, M. Dubick, I. Torres Filho. U.S. Army Inst. of Surg.
Res., San Antonio.
B50
948.8
Plasma Biomarkers of Glycocalyx Shedding
after Hemorrhage and Resuscitation: Correlation with
Microvascular Events. I. Torres Filho, L.N. Torres, C. Salgado,
C. Valdez, M.A. Dubick. U.S. Army Inst. of Surg. Res., Fort
Sam Houston, TX.
B51
948.9
Catecholamine
Induced
Takotsubo
Cardiomyopathy: The Role of Coronary Metabolic Blood
Flow Regulation in Apical Ballooning. V. Ohanyan, L. Yin, R.
Bardakjian, M. Khayata, C.L. Kolz, M. Enrick, B. Schatmeyer,
V. Perera, D. Janota, T. Hakobyan, W.M. Chilian. Northeast
Ohio Med. Univ.
B52
948.10 Mechanistic Investigation of Reversal of
Endothelial Dysfunction in Hyperglycemia. H. Patel, J. Chen,
M. Kavdia. Wayne State Univ.
B53
948.11 Endothelial Dysfunction in Children after
Cardiopulmonary Bypass. L. Krispinsky, F. Lamb, R. Stark, D.
Parra. Vanderbilt Children’s Hosp.
B54
948.12 Exercise Training Prophylactically Abrogates
Chronic Stress-Induced Cerebrovascular Dysfunction in
Lean and Obese Zucker Rats. S.D. Brooks, K. Branyan, E.
DeVallance, W.J. Sheets, R. Skinner, R. Bryner, M. Olfert,
P.D. Chantler, J.C. Frisbee. West Virginia Univ.
B55
948.13 Comparison of Endothelial Function in Preand Post-exercise States between Obese and Normal-Weight
Children. B.D. Tran, A. Chiu, G. Ganesan, H. Pham, M.
Martinez, P.R. Galassetti. Univ. of California, Irvine.
B56
948.14 Effects of Hydrogen Sulfide on Renal and
Mesenteric Blood Flow. A. Barrera, J. Naik, N.L. Kanagy.
Univ. of New Mexico Hlth. Sci. Ctr.
B57
948.15 Interventions Blunting Systemic Inflammation
and Oxidant Stress Improve Depressive Symptoms and
Vascular Function in a Model of Metabolic Syndrome.
W.J. Sheets, S.D. Brooks, P. Chantler, J. Frisbee. West
Virginia Univ.
B58
948.16 Melatonin Preserves Blood-Brain Barrier
Integrity and Permeability via Matrix Metalloproteinase-9
Inhibition. C. Anasooya Shaji, H. Alluri, K. Wiggins-Dohlvik,
M.R. Beeram, M.L. Davis, B.L. Tharakan. Texas A&M Univ.
Hlth. Sci. Ctr. and Baylor Scott and White Hlth.
311
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PHYSIOLOGYMONDAY
949. MICROCIRCULATION: PERICYTES AND
STEM CELLS
Poster
Exhibit Halls A-D
B59
949.1
The Role of Pericytes for Angiogenesis
in Skeletal Muscle Tissue. B. Hoier, Y. Hellsten. Univ.
of Copenhagen.
B60
949.2
Evaluation of Stem Cell Fate in Cultured
Microvascular Networks. M.S. Azimi, A. Strong, M. Dutreil, R.
Fishel, B. Bunnell, W.L. Murfee. Tulane Univ.
B61
949.3
Contractile Pericytes Determine the Direction
of Blood Flow at Capillary Bifurcations. A.L. Gonzales, T.A.
Longden, B. Shui, M.I. Kotlikoff, M.T. Nelson. Univ. of Vermont,
Cornell Univ. and Sch. of Med., Univ. of Manchester, U.K.
950. MICROCIRCULATION: PERMEABILITY/FLUID
AND SOLUTE EXCHANGE/GLYCOCALYX
Poster
951. MICROCIRCULATION: TISSUE-MICROVESSEL
INTERACTIONS/EXTRACELLULAR MATRIX
Poster
Exhibit Halls A-D
B62
950.1
Sphingosine
1-Phosphate
Attenuates
Combined Acute Alcohol Intoxication and Hemorrhagic-Shock/
Resuscitation-Induced Microvascular Hyperpermeability in Rat
Mesentery. T.M. Doggett, N.G. Alves, S.Y. Yuan, J.W. Breslin.
Univ. of South Florida.
B63
950.2
Rapid Increases in Fluid Shear Stress Elicit
Local Lamellipodia and Elevate Microvascular Endothelial
Barrier Function. S.G. Spampinato, J.W. Breslin. Univ. of
South Florida.
B64
950.3
Activation of RhoA, but Not Rac1, Mediates
Early Stages of S1P-Induced Endothelial Barrier Enhancement.
X. Zhang, S. Adderley, J. Breslin. Univ. of South Florida.
B65
950.4
HS-FGF2-FGFR1
Signaling
Contributes
to Pulmonary Endothelial Glycocalyx Reconstitution. E.P.
Schmidt, Y. Yang, M. Suflita, F. Zhang, K. Dailey, S. Haeger,
J. Ford, R. Linhardt. Univ. of Colorado, Aurora and Rensselaer
Polytech Inst.
B66
950.5
IL1β Disrupts Barrier Integrity and Elicits
Formation of Focal Adhesions in Lymphatic Endothelial Cells.
S.P. Adderley, X.E. Zhang, J.W. Breslin. Univ. of South Florida.
B67
950.6
Sigma-1 Receptor Agonists Compromise
Barrier Function of Endothelial Cell Monolayers with
Differential Impact on Cells Derived from Cardiac or Dermal
Microcirculation and Dermal Lymphatics. C. Schecker, S.
Adderley, J.W. Breslin. Univ. of South Florida.
B68
950.7
The Role of Matrix Metalloproteinases in
Platelet Endothelial Cell Adhesion Molecule-1 Loss in Diabetic
Retinopathy: In Vivo and In Vitro Studies. R.S. Eshaq, N.
Harris. LSU Hlth. Sci. Ctr., Shreveport.
312
B69
950.8
Sphingosine-1-Phosphate
and
8-pCPT2′-O-Me-cAMP Can Restore Alcohol-Induced Junctional
Disorganization and Barrier Dysfunction of Human Brain
Microvascular Endothelial Cells. N.G. Alves, S. Adderley, S.
Yuan, J. Breslin. Univ. of South Florida.
B70
950.9
Lymphatic Vascular Integrity Is Disrupted in a
Mouse Model of Diabetes: Dual Regulation by Nitric Oxide. J.P.
Scallan, M.A. Hill, M.J. Davis. Univ. of South Florida and Univ.
B71
950.10 Optimization of the Hemodynamic of the
Kidney and Preservation of Glycocalyx during Kidney
Transplantations – A Combination of Fluid Therapy and Low
Dose Norepinephrine. J.K. Eriksen, N. Moeslund, L.H.
Nielsen, J.A.K. Petersen, B. Jespersen, H. Birn. Aarhus Univ.
Hosp. and Aarhus Univ., Denmark.
B72
950.11 Bulk Flow of Interstitial Fluid: A Watershed in
the Brain Parenchyma. B. Bedussi, M.G.J.T.B. van Lier, J.W.
Bartstra, J. de Vos, M. Siebes, E. van Bavel, E.N.T.P. Bakker.
Acad. Med. Ctr., Amsterdam.
B73
950.12 Hydrogen Sulfide Metabolism Regulates
Endothelial Permeability. S. Yuan, S. Pardue, A.W. Orr, C.G.
Kevil. LSU Hlth. Sci. Ctr., Shreveport.
Exhibit Halls A-D
B74
951.1
IL-17- and TNFα-Activation Induces Proinflammatory Paracrine Signaling and Basement Membrane
Remodeling by Human Pericytes. H.M. Lauridsen, R. Liu, J.S.
Pober, A.L. Gonzalez. Yale Univ. and Yale Univ. Sch. of Med.
B75
951.2
Nrf2 Deficiency Attenuates Synaptic Plasticity
in Mice, Mimicking the Aging Phenotype. M.N. ValcarcelAres, Z. Tucsek, S. Tarantini, P. Hertelendy, T. Gautam, W.E.
Sonntag, F. Deak, Z. Ungvari, A. Csiszar. Univ. of Oklahoma
Hlth. Sci. Ctr. and Univ. of Szeged, Hungary.
B76
951.3
Mechanisms Coordinating Vascular Smooth
Muscle Adhesion to the Extracellular Matrix during Contraction.
H. Huang, Z. Sun, M.A. Hill, G.A. Meininger. Univ.
952. MICROCIRCULATION II
Poster
Exhibit Halls A-D
B77
952.1
Human Pericardial Fluid-Derived Endothelin
Elicits Arterial Constriction. Z. Nemeth, A. Cziraki, S.
Szabados, I. Horvath, A. Koller. Univ. of Pecs, Hungary, New
York Med. Col. and Univ. of Phys. Educ., Hungary.
MONDAYPHYSIOLOGY
B78
952.2
Blunted Endothelial-Dependent Vasodilation
in the Cutaneous Microvasculature of College-Aged African
Americans. J.C. Patik, C. Hurr, K.M. Christmas, R.M.
Brothers. Univ. of Texas at Arlington, George Washington
Univ. and Univ. of Texas at Austin.
B79
952.3
Norepinephrine Induces Endothelial Albumin
Uptake via ROS and Src-Dependent Mechanisms. A.Z.
Chignalia, A. Isbatan, R. Minshall, R. Dull. Univ. of Illinois
at Chicago.
B80
952.4
Disruption of Interleukin 12 Stimulates and
Enhances Angiogenesis in Type 2 Diabetes. M.A.E. Ali, V.
Mali, S. Haddox, S. Abdelghani, S. Eldeek, A. Abulfadl, S.
Belmadani. Eastern Virgina Med. Sch. and Assiut Univ., Egypt.
B81
952.5
Stromal Interaction Molecule 1 Disruption
Protects Myocardial from Ischemia - Reperfusion Injury. V.R.
Mali, M. Ali, S. Haddox, S. Belmadani, M.Trebak, K. Matrougui.
Eastern Virginia Med. Sch. and Penn State, Hershey.
B82
952.6
Transient Exposure to Serotonin + L-NAME
Activates Early Processes Mediating Inward Remodeling
of Cremasteric Arterioles, In Vivo. C. Foote. Univ.
B83
952.7
EET-Dependent Attenuation of Coronary
Myogenic Constriction in Response to Deletion/Downregulation
of Soluble Epoxide Hydrolase. G. Froogh, J. Qin, S. Kandhi,
H. Jiang, D. Sun, A. Huang. New York Med. Col.
B84
952.8
Comparison in Young White European and
South Asian Men of Endothelium-Dependent Cutaneous
Vasodilator Responses: Contribution of Cyclooxygenase
Products. K. Tsitoglou, U. Martin, J. Marshall. Univ. of
Birmingham, U.K.
B85
952.9
Nox1 Deletion Rescues Microvascular
Dysfunction in Obese Mice. J.A. Thompson, J. Mintz, D.J.
Fulton, D.W. Stepp. Georgia Regents Univ.
B86
952.10 Effects of Serelaxin on Renal Microcirculation
in Rats under Control and High Angiotensin Environments.
W. Shao, M.C. Prieto, C. Gonzalez-Arancibia, L.G. Navar.
Tulane Univ. Sch. of Med.
953. NOVEL MECHANISMS OF
CEREBROVASCULAR DYSFUNCTION
Poster
Exhibit Halls A-D
B87
953.1
Role
of
Cerebrovascular
Endothelial
Dysfunction and Oxidative/Nitrative Stress in Impaired
Functional Hyperemia: Implications for Age-Related Vascular
Cognitive Impairment. S. Tarantini, P.J. Toth, A. Davila, M.N.
Valcarcel-Ares, Z. Tucsek, B. Varamini, P. Ballabh, W.E.
Sonntag, J.A. Baur, A. Csiszar, Z. Ungvari. Univ. of Oklahoma
Hlth. Sci. Ctr., Univ. of Pecs, Hungary, Univ. of Pennsylvania,
Biola Univ. and New York Med. Col.
B88
953.2
Treatment with the Mitochondrial-Targeted
Antioxidant Peptide SS-31 Improves Cerebromicrovascular
Function in Aged Mice. S. Tarantini, P. Hertelendy, M.N.
Valcarcel-Ares, T. Gautam, Z. Tucsek, A. Csiszar, Z. Ungvari.
Univ. of Oklahoma Hlth. Sci. Ctr. and Univ. of Szeged, Hungary.
B89
953.3
Novel
Splice
Variant
of
nNOS
in
Cerebrovascular Endothelial Cells Contributes to Superoxide
and Peroxynitrite Generation. V.N. Sure, I. Merdzo, V.M.
Abraham, N.P. Jain, G. Unis, T.P. Baker, N.R. Peterson, A.O.
Gordon, A.L. Chen, I. Rutkai, D.W. Busija, P.V.G. Katakam.
Tulane Univ. Sch. of Med.
B90
953.4
Mitochondrial Mechanisms of Nelfinavir
Toxicity in Human Brain Microvascular Endothelial Cells. G.
Unis, T.P. Baker, G. Rajaprabhakaran, V.N. Sure, N.P. Jain,
V.M. Abraham, N.R. Peterson, A.O. Gordon, A.L. Chen, Z.
Cama, D. Mondal, P.V.G. Katakam. Tulane Univ. Sch. of Med.
B91
953.5
Critical Role of Telomerase in Regulating
Cerebral Vascular Function and Redox Environment. K. AitAissa, J. Hockenberry, D.D. Gutterman, A. Geurts, A.M.
Beyer. Med. Col. of Wisconsin.
B92
953.6
Smooth Muscle Specific Expression of a
Dominant Negative Cullin 3 Mutant (Cul3Δ9) Causes Vascular
Dysfunction in Mice Mediated by RhoA/Rho-Kinase. L.N.
Agbor, S-R.C. Ibeawuchi, C. Hu, F.W. Quelle, C.D. Sigmund.
Univ. of Iowa.
B93
953.7
Impaired Myogenic Response of MCA
Elevates Transmission of Pressure to Penetrating Arterioles
and Contributes to Cerebral Vascular Disease in Aging
Hypertensive FHH Rats. F. Fan, M. Pabbidi, R.C.S. Lin, Y.
Ge, E.P. Gomez-Sanchez, G.K. Rajkowska, M. Moulana,
E. Gonzalez-fernandez, J. Sims, M.R. Elliott, I.A. Paul, A.P.
Alexander, T.H. Mosley, D.R. Harder, R.J. Roman. Univ. of
Mississippi Med. Ctr. and Med. Col. of Wisconsin.
B94
953.8
Treatment of Acute Focal Ischemic Stroke
with Peroxynitrite Decomposition Catalyst Does Not Improve
Reperfusion, Infarct or Hemorrhage in Chronic Hypertensive
Rats. S.L. Chan, J.G. Sweet, M.J. Cipolla. Univ. of Vermont.
B95
953.9
Mitochondria-eNOS-Estrogen Axis Provides
Pathway to Protection against Stroke. I. Rutkai, S.V. Wunnava,
I. Merdzo, P.V. Katakam, D.W. Busija. Tulane Univ.
B96
953.10 Chronic Nicotine Exposure Exacerbates
Transient Focal Cerebral Ischemia-Induced Brain Injury.
C. Li, H. Sun, D.M. Arrick, W.G. Mayhan. LSU Hlth. Sci.
Ctr., Shreveport.
B97
953.11 Early Post-ischemic Blood-Brain Barrier
Disruption in Obesity. C. Li, Z. Jiang, D.M. Arrick, W. Lu, K.D.
McCarter, H. Sun. LSU Hlth. Sci. Ctr., Shreveport, The Second
Xiangya Hosp. of Central South Univ., China.
B98
953.12 Mitigation
of
Nitrosative
Stress
and
Inflammation by Vitamin C in Cardiomyopathy. G. Akolkar,
A.K. Bagchi, D.dS. Dias, K. de Angelis, D. Jassal, P.K.
Singal. Univ. of Manitoba and Univ. Nove de Julho, Brazil.
B99
953.13 Pharmacological Inhibition of NAD(P)H
Oxidase with the Peptide gp91ds-tat during Ischemic Stroke
Reduces Infarct Volume and Improves Vascular Reactivity in
Obese Zucker Rats. S.D. Brooks, K. Branyan, S. Asano, H.
Hu, X. Ren, R.W. Brock, J.C. Frisbee, P.D. Chantler. West
Virginia Univ.
B100 953.14 In Utero Exposure to Alcohol Alters Reactivity
of Cerebral Arterioles. S.G. Cananzi, W.G. Mayhan. LSU Hlth.
Sci. Ctr. Shreveport.
313
M
O
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PHYSIOLOGYMONDAY
954. CARDIOPULMONARY EFFECTS OF
ENVIRONMENTAL STRESSORS
Poster
Exhibit Halls A-D
B101 954.1
Exercise Mitigates Calpain 1-Induced Cardiac
Dysfunction through PCP4 in Diabetes. P. Chaturvedi,
G.H. Kunkel, A. Familtseva, A. Kalani, S.C. Tyagi. Univ.
of Louisville.
B102 954.2
Cardiovascular Implications of Environmental
Stressors, a Health Call to Protect the Planet. P. Cabrales, A.
William. UCSD.
B103 954.3
Endothelial
Hyper-permeability
and
Cardiomyocyte Dysfunction following Coronary Artery Bypass
Grafting. M. Velten, G.D. Duerr, M. Hamiko, S. Frede, L.K.
Rogers, G. Baumgarten, A. Hoeft, T. Hilbert. Univ. Med. Ctr.
Bonn and Nationwide Children’s Hosp., Columbus, OH.
B104 954.4
Maternal Separation Stress Causes Misp[rogramming of Arterial Smooth Muscle Maturation. J. Reho,
S.A. Fisher. Univ. of Maryland Sch. of Med.
B105 954.5
Synergistic Amplification of Lipopolysaccharideand Histamine-Induced TLR4 and COX2 Expression by
Cigarette Smoke Extract and Nicotine in Endothelial Cells.
R.S. Barua, M. Sharma, A. De, J. Zhou, D. Parashara, K.N.
Dileepan. Kansas City VA Med. Ctr. and Univ. of Kansas
Med. Ctr.
B106 954.6
Bromine Inhalation in Pregnant Mice Induces
Systemic and Pulmonary Hypertension, Fetal Growth
Restriction, Heart Failure and Death. J.A. Lambert, M. Carlisle,
A. Lam, S. Aggarwal, A. Zaky, L. Dell’Italia, W. Bradley, T.
Jilling, S. Matalon. Univ. of Alabama at Birmingham.
B107 954.7
Exposure to PM2.5 during the First Trimester
Contributes to Adult Cardiac Dysfunction. V. Tanwar, M. Gorr,
C. Eichenseer, L. Wold. The Ohio State Univ.
B108 954.8
Influence of Acute Lower Limb Heating on
Clinical Measures and Functional Capacity in Peripheral
Artery Disease. T.K. Pellinger, C.B. Pearce, G.H. Simmons.
Salisbury Univ. and Univ. of Missouri-Columbia Sch. of Med.
B109 954.9
Thermoregulatory and Ventilatory Responses
in Humans with a Patent Foramen Ovale during Passive
Cooling While Immersed in 20°C Water. J.T. Davis, M.W. Hay,
A.M. Hardin, A.T. Lovering. Univ. of Oregon.
B110 954.10 Hookah Smoking Does Not Constrict Human
Coronary Microvessels. M. Rezk-Hanna, M.D. Nelson, F.
Rader, O. Mason, X. Tang, S. Shidban, R. Rosenberry, N.L.
Benowitz, R.M. Elashoff, J.R. Lindner, R.G. Victor. CedarsSinai Med. Ctr., UCLA, UCSF and Oregon Hlth. & Sci. Univ.
B111 954.11 Differential Effects of Hookah versus Cigarette
Smoking on Endothelial Function. M. Rezk-Hanna, L. Doering,
W. Robbins, O. Mason, J. Choung, N.L. Benowitz, R.M.
Elashoff, L. Sarna, R. Victor. Cedars-Sinai Med. Ctr., UCLA
Sch. of Nursing, UCSF and UCLA.
B112 954.12 Post-Exercise Changes in Endothelin-1 in
Military Veterans with Respiratory Complaints. P. Salcedo, X.
Jiao, Y. Chen, J.C. Klein, D. Ndirangu, M.R. Condon, M.J.
Falvo. New Jersey Med. Sch. and VA NJ Hlth. Care Syst.
East Orange.
314
B113 954.13 Effect of Transit Time and Gas Density on the
Conservation of Agitated Saline Contrast in an In Vitro Model of
the Pulmonary Circulation. H. Hackett, L. Boulet, P. Dominelli,
G. Foster. Univ. of British Columbia-Okanagan.
955. BLOOD PRESSURE REGULATION II
Poster
Exhibit Halls A-D
B114 955.1
Higher Hemoglobin A1c and C-Reactive Protein
but Not Aortic Stiffness Are Independently Associated with
Blunting of Nocturnal Systolic Blood Pressure Dipping among
Middle-Aged/Older Adults with Obesity and Prediabetes. A.L.
Sindler, G.Z. Kalil, C.J. Wagner, A. Lane-Cordova, J.G.
Fiedorowicz, W.G. Haynes, G.L. Pierce. Univ. of Iowa.
B115 955.2
Nocturnal Blood Pressure Dipping in
Normotensive Adults: Effect of Dietary Sodium and Sex. M.
Brian, A. Dalpaiz, E. Matthews, S. Lennon-Edwards, D.
Edwards, W. Farquhar. Univ. of Delaware.
B116 955.3
Endothelial Calreticulin and Its Role in Vascular
Function. L. Biwer, M. Good, S. Sonkusare, B. Isakson. Univ.
of Virginia.
B117 955.4
Aging Increases Reactive Oxygen Species
and Interleukin-17 Concentrations in Peroxisome Proliferator
Activated Receptor-alpha Knockout Mice during Angiotensin
II Hypertension through a NADPH Oxidase Subunit-2
Mechanism. U. Ananaba, N.C. Williams, J.S. Allard, D.L. Lee.
Howard Univ.
B118 955.5
Acute Effects of Dietary Nitrate Supplementation
on Peripheral and Central Blood Pressure in Post-menopausal
Women. D.J-K. Kim, M.A. Barrett, D.J. Moore, M.P. Flanagan,
C. Roe, D.B. Kim-Shapiro, D.N. Proctor. Penn State, Penn
State Harrisburg, Penn State Hershey and Wake Forest Univ.
B119 955.6
Brain-Derived Neurotrophic Factor Acting
within the Paraventricular Nucleus Induces Blood Pressure
Elevations under Permissive Control of Angiotensin II and
Mediates Pressor Responses to Acute Stress. B. Erdos, C.L.
Schaich, N.C. Cruickshank, T.L. Wellman. Univ. of Vermont.
B120 955.7
Effects of Arginine Vasopressin Deficiency
on Long-Term Arterial Blood Pressure in Normal and
Spontaneously Hypertensive Rats. G.M. VillanuevaRodriguez, A. Organista-Esparza, V. Biñuela-Berni, P.
Herrera-Carreon, M. Tinajero-Ruelas, C.V. Rivera-Cerecero,
R. Chavira-Ramirez, K. Kovacs, A. Quintanar-Stephano.
Autonomous Univ. of Aguascalientes, UNAM and Salvador
Zubirán Natl. Inst. of Hlth. Sci. and Nutr., Mexico City and
St.Michael´s Hosp., Toronto.
B121 955.8
The Role of Nitric Oxide in the Expression of
the Human Intermediate and Small Conductance CalciumActivated Potassium Channels, KCa3.1 and KCa2.3 H.M.
Jones, Y.M. Hussain. Lake Erie Col. of Osteo. Med., PA.
B122 955.9
Metaboreflex Contribution to Peak Pressor
Response Achieved during Fatiguing Intermittent Static
Exercise Is Attenuated in Postmenopausal Women. M.A.
Barrett, J-K. Kim, N.M. Garvin, M.J. De Souza, J.A.
Pawelczyk, D.N. Proctor. Penn State.
MONDAYPHYSIOLOGY
956. DIABETES AND INSULIN RESISTANCE II
Poster
Exhibit Halls A-D
B123 956.1
Relation between Type 2 Diabetes and m.1382
A>C Polymorphism Which Occurs Amino Acid Replacement
(K14Q) of Mitochondria-Derived MOTS-c. H. Zempo. Juntendo
Univ., Japan.
B124 956.2
Glutathione
S-Transferase-P and
JNK
Activation in Glucose Intolerance in Mice. S. Ghosh
Dastidar, G. Jagatheesan, A. Bhatnagar, D.J. Conklin. Univ.
of Louisville.
B125 956.3
Knockout of TSP-1 Prevents HyperglycemiaInduced Atherosclerosis in STZ-Treated ApoE-/- Mice. R.
Ganguly, S. Sahu, P. Raman. Northeast Ohio Med. Univ. and
Kent State Univ. Sch. of Biomed. Sci.
B126 956.4
Divergent Response of Circulating CTRP3
Levels to Obesity between Males and Females. J.M. Peterson,
R.M. Wagner, K. Sivagnanam, W.A. Clark. East Tennessee
State Univ.
B127 956.5
Increasing Muscle Mass Improves Cavernosal
Function in Obesity. N.K. MicKinac, S. Larion, J.D. Mintz, D.J.
Fulton, D.W. Stepp. Med. Col. of Georgia.
B128 956.6
Detrimental Changes in Perivascular Adipose
Gene Expression in Metabolic Syndrome. A. Seldomridge, E.
DeVallance, K. Lemaster, K. Branyan, J. Frisbee, V. Setola,
P. Chantler. West Virginia Univ.
B129 956.7
β-Cell Deletion of Nr4a1 and Nr4a3 Nuclear
Receptors Impedes Mitochondrial Respiration and Insulin
Secretion. M.S. Reynolds, C.R. Hancock, J.D. Ray, K.B.
Kener, J.M. Hardman, J.S. Tessem. Brigham Young Univ.
B130 956.8
Carbonic Anhydrase Mediates Hepatic
Steatosis and Vascular Stiffness Induced by a Western Diet.
T. Malcolm, A. Aroor, W. Bivin, J. Sowers, R. Woodman, W.
Lockette. Univ. of Missouri-Columbia.
B131 956.9
Differential Effects of Toll-Like Receptors 2 and
4 in Endotoxin-Induced Vascular Dysfunction. M.L. Battson,
D.M. Lee, S. Hou, D.K. Jarrell, K.S. Santangelo, K.A. CoxYork, C.L. Gentile. Colorado State Univ.
B132 956.10 Sex Differences in the Expression of Cardiac
miR-29 Family MicroRNAs in Diabetic Male and Female Rats
and Its Correlation with Increased Risk for Coronary Artery
Disease in Diabetic Females. K. Lum-Naihe, L. Pulakat. Univ.
of Missouri-Columbia and Harry S Truman Mem. VA Hosp.
957. ENDOTHELIAL CELL BIOLOGY I
Poster
Exhibit Halls A-D
B133 957.1
Nitric Oxide Donor [Ru(terpy)(bdq)NO]3+
(TERPY) Promotes eNOS Activation. S.R. Potje, S.D. Oliveira,
Z. Chen, M.G. Bonini, R.S. da Silva, L.M. Bendhack, C.
Antoniali, R.D. Minshall. Univ. of Illinois at Chicago, Univ. of
São Paulo and State Univ. of São Paulo, Brazil.
B134 957.2
Heme
Oxygenase-1
Counteracts
HIV
Protease Inhibitor-Mediated Endothelial Cell Dysfunction.
W. Durante, X-m. Liu, Z.E. Durante, K.J. Peyton. Univ.
B135 957.3
Glutaminase Stimulates the Proliferation of
Human Endothelial Cells. W. Durante, X-m. Liu, B. Yates, Y.
Yu, K.J. Peyton. Univ. of Missouri-Columbia.
B136 957.4
Cross Tolerance and Potentiation of Toll-Like
Receptors in Endothelial Cells. R.J. Stark, S.R. Koch, F.S.
Lamb, E.R. Sherwood. Vanderbilt Univ.
B137 957.5
The Early Postmenopausal Phase Is
Associated with a Decline in Vascular Function: Is the
Prostanoid System to Blame? M. Nyberg, J. Egelund, M.B.
Nielsen, A. Mogensen, Y. Hellsten. Univ. of Copenhagen.
B138 957.6
Assessing the Pleiotropic Role of Pravastatin™
on the Expression of AQP1 in Vascular Endothelial Cells
Cultured under Static, Venous, and Arterial Flow Conditions In
Vitro. R.J. Crum, C.M. Krane. Univ. of Dayton.
B139 957.7
Reciprocal Regulation of eNOS and Caveolin-1
Function in Endothelial Cells. Z. Chen, R. Minshall. Univ of
Illnois at Chicago.
B140 957.8
Helium Induces Caveolin Secretion and
Decreases Permeability in Human Umbilical Vein Endothelial
Cells. M.A. Landau, K.F. Smit, M. Warmbrunn, B. Preckel,
M.W. Hollmann, H.H. Patel, M. Albrecht, N.C. Weber. AMC,
Univ. of Amsterdam, UCSD, and Univ. Hosp. SchleswigHolstein, Germany.
B141 957.9
Endothelium-Derived
Microvesicles
Alter
Permeability of Human Brain Microvascular Endothelial
Monolayers. L.W. Hunter, M. Jayachandran, V.M. Miller.
Mayo Clin.
B142 957.10 N-myc Downstream Regulated Gene-1
Promotes Vascular Inflammation through Activating Both NFκB and c-Jun/AP-1 Pathways in Endothelial Cells. G. Zhang,
Q. Qin, B. Yi, Z. Guo, X. Wei, L. Yin, Y. Yin, F. Cheng, J. Sun.
Thomas Jefferson Univ. and Changhai Hosp., China.
B143 957.11 Wild Type p53 Regulates Endothelial Barrier
Function by Mediating Rac1 Signaling and Inhibiting RhoA
Activity. N. Barabutis, C. Birmpas, G. Thangjam, B.W.
Gregory, M. Clements, J. Newton, J.D. Catravas. Old
Dominion Univ. and Eastern Virginia Med. Sch.
B144 957.12 Changes in Triglyceride-Rich Lipoprotein
Composition in Response to a High-Fat Meal Promote
Endothelial Inflammation in Hypertriglyceridemic Subjects. A.
Rajamani, A. Fernandez, S.I. Simon, A.G. Passerini. Univ. of
California, Davis.
B145 957.13 Enteroendocrine Cell Is a Source of VEGF-A in
the Neonatal Intestine. X. Yan, X. Liu, E. Managlia, I. De Plaen.
Ann & Robert H. Lurie Children’s Hosp. of Chicago.
958. HEART FAILURE II
Poster
Exhibit Halls A-D
B146 958.1
High Intensity One-Legged Cycling Improves
Functional Sympatholysis and Aerobic Fitness in Chronic
Heart Failure. G.D.W. Munch, U.W. Jepsen, B.K. Pedersen,
J. Rosenmeier, S.P. Mortensen. Rigshosp., Copenhagen and
Univ. of So. Denmark.
315
M
O
N
PHYSIOLOGYMONDAY
B147 958.2
Ventilatory Efficiency and Oscillatory Breathing
as Clinical Markers of Surgical Outcomes in Heart Failure. N.
Jesse, E. Raichlin, H. Schultz. Univ. of Nebraska Med. Ctr.
B148 958.3
Ufm1 E3 Ligase Ufl1 Is Essential for Adaptive
Hypertrophy and ER Stress Response in the Heart. J. Li,
G. Yue, W. Ma, H. Li, A. Zhang, F. Li, H. Li, H. Su. Georgia
Regents Univ. and Univ. of Minnesota, Minneapolis.
B149 958.4
How the Activity of PKCα Is Increased and
Maintained in Heart Failure Despite the Up-Regulation
of Molecular Braking Mechanism? N. Aslam, I. Zaheer.
BioSystOmics and The Methodist Hosp., Houston.
B150 958.5
Repetitive ROS Injury Leads to Inactivation
of NRF2-Induced Antioxidant Defense and Mitochondrial
Dysfunction in Ischemic Heart Failure. T. Liu, A.A. Knowlton.
Univ. of California, Davis and DVA No. California, Sacramento.
B151 958.6
The Effect of Monocrotaline-Induced Heart
Failure on Left- and Right-Ventricular Function. S-J. Guild,
J-C. Han, A. Power, M-L. Ward, L.A. Nisbet, D.S. Loiselle.
Univ. of Auckland.
B152 958.7
Doxorubicin Decreases Cyclooxygense-2
Levels in Heart, Brain, and Pial Arteries from Ovariectomized
Female Rats. R. Gonzales, P. Raman, N. Vijayavel, C.
Kerrigan, T. Hale, C. Carroll, J. Dickinson, S. Angadi. Univ.
of Arizona, Midwestern Univ., Arizona State Univ. Sch. of Nutr.
and Hlth. Promo. and Mayo Clin.
B153 958.8
Cardiac Fibroblast Growth Factor-16 Increases
Efflux Drug (ABC) Transporter Production and Resistance to
Doxorubicin-Induced Cardiomyocyte Death. J. Wang, P.A.
Cattini. Univ. of Manitoba.
959. HYPERTENSION I
Poster
Exhibit Halls A-D
B154 959.1
Sex Differences in Hypertension: A Modeling
Study. Y. Chen, A. Edwards, J. Sullivan, A. Layton. Duke Univ.,
Res. Ctr. des Cordeliers, Paris and Georgia Regents Univ.
B155 959.2
The Role of the Gut Microbiota in Obstructive
Sleep Apnea-Induced Hypertension. D. Durgan, B. Ganesh,
J. Cope, N. Ajami, S. Phillips, J. Petrosino, E. Hollister, R.
Bryan. Baylor Col. of Med. and Texas Children’s Microbiome
Ctr., Houston.
B156 959.3
Chronic Inhibition of Endoplasmic Reticulum
Stress Attenuates Cardiovascular but Not Appetite Responses
to MC3/4R Antagonism in SHR. J.M. do Carmo, A.A. da Silva,
Z. Wang, J.E. Hall. Univ. of Mississippi Med. Ctr. and Org.
Educ. Barao de Maua, Ribeirão Preto, Brazil.
B157 959.4
Spilanthol from Acmella oleracea Lowers Na+K+-2Cl--Cotransporter Activity and Water Channel Aquaporin
2 Membrane Expression in Mouse Renal Cells. A. Gerbino,
G. Schena, L. Milella, R. Miglionico, M. Armentano, A.F.
Barbosa, G. Procino, M. Svelto, M. Carmosino. Univ. of Bari,
Univ. of Basilicata, Italy and Fed. Rural Univ. of Rio de Janeiro.
B158 959.5
Immunological
Memory
Exacerbates
Responses to Repeated Hypertensive Stimuli. H.A. Itani, L.
Xiao, M.A. Saleh, J. Wu, M. Pilkinton, B.L. Dale, N. Barbaro,
J. Foss, A. Kirabo, K. Montaniel, A. Norlander, W. Chen,
R. Sato, L.G. Navar, S. Mallal, M. Madhur, K. Bernstein, D.
Harrison. Vanderbilt Univ., Univ. of Campinas, São Paulo,
Tulane Univ. and Cedars-Sinai Med. Ctr.
316
B159 959.6
Longitudinal Study on Independent and Joint
Effect of Brachial-Ankle Pulse Wave Velocity and Blood
Pressure Control on Incident Stroke in Hypertensive Patients.
Y. Song, B. Xu, R. Xu, R. Tung, E. Frank, W. Tromble, W. Yang,
Y. Zhang, J. Li, X. Qin, B. Wang, F.F. Hou, Y. Huo, H. Wang.
So. Med. Univ., China, River Hill H.S., Clarksville, MD, Lower
Moreland H.S., Huntingdon Valley, PA, Peking Univ. First Hosp.
and Temple Univ. Sch. of Med.
B160 959.7
Involvement of Inhibitor Kappa B Kinase 2 in
the Elevated Vascular Tone of Spontaneously Hypertensive
Rats. S-K. Choi, M. Lim, Y. Kwon, Y-H. Lee. Col. of Med., Brain
Korea 21 Plus Proj. for Med. Sci., Yonsei Univ., South Korea.
B161 959.8
Using Fiber-Optic Confocal Microscopy
for In Vivo Imaging of Brain and Kidney Vasculature and
Haemodynamics. A.M. Tomiak-Baquero, K.E. Lewis, E.
Roloff, S. Kasparov, M.P. Koeners, J.F.R. Paton. Univ.
of Bristol.
B162 959.9
Reduced Repair Capacity and Endothelial
Apoptosis Mediated by Retrograde Blood Flow in Hypertension.
H.N.M. Rocha, V.P. Garcia, G.M.B. Silva, D.G.V. Lima, G.M.
Silva, M.O. Campos, J.D.M. Mattos, A.C.L. Nóbrega, I.A.
Fernandes, N.G. Rocha. Fluminense Fed. Univ., Brazil.
B163 959.10 Overweight Was Related with Sympathetic
Activation in Offspring of Hypertensives. A.O. Viana, F.A.
Santa Rosa, M.C. Nascimento, G.L. Shimojo, J. De Paiva, K.
De Angelis. Univ. Nove de Julho, São Paulo.
960. ROS/CV INJURY II
Poster
Exhibit Halls A-D
B164 960.1
Severe Sleep Apnea Is Associated with
Telomere Lengthening. K. Polonis, P. Singh, C. Becari,
N. Covassin, B. Druliner, R. Johnson, L. Boardman, V.K.
Somers. Mayo Clin.
B165 960.2
Ameliorative Effect of Gallic Acid on
Doxorubicin-Induced Cardiotoxicity in Adult Wistar Rats. O.A.
Adejumobi, O. Orotusin, A. Oyagbemi, A. Adedapo, C.
Olaogun, T.O. Omóbòwálé. Univ. of Ibadan, Nigeria.
B166 960.3
Altered Nitric Oxide Signaling and Oxidative
Stress Increase Pulmonary Arteriolar Tone and Cause Lung
Fibrosis in a Mouse Model of Alzheimer’s Disease. A.M.
Roberts, R. Jagadapillai, R. Vaishnav, R.P. Friedland, R.
Drinovac, X. Lin, E. Gozal. Univ. of Louisville Sch. of Med.
B167 960.4
Postconditioning Reduces Early Reactive
Oxygen Species Production in the Brain in a Porcine Model
of Cardiac Arrest and Resuscitation. T.R. Matsuura, D.
Yannopoulos, J.A. Bartos, M.D. Olson, J.N. Rees, A.
Tsangaris, K.C. Shekar, S.H. McKnite, T.P. Aufderheide, M.P.
Bienengraeber, R.W. Neumar, A.E. Dikalova, S.I. Dikalov,
H.F. Douglas, M.M. Salzman, M.L. Riess. Univ. of Minnesota,
Minneapolis, Med. Col. of Wisconsin, Univ. of Michigan,
Vanderbilt Univ. and TVHS VA Med. Ctr., Nashville.
B168 960.5
Malignant Hyperthermia-Associated Mutation
of RyR1 Induces Mitochondrial Damages and Cellular
Oxidation in the Heart. J. O-Uchi, J. Mishra, B.S. Jhun, S.
Hurst, D. Fu, L. Gomez, S-S. Sheu. Thomas Jefferson Univ.
and Univ. Lyon.
MONDAYPHYSIOLOGY
B169 960.6
Angiotensin II-Mediated Mitochondrial Ca2+
Uptake and Superoxide Generation Activate Proliferative
Pathway in Neonatal Cardiac Fibroblasts. J. O-Uchi, D. Fu, J.
Mishra, B. Jhun, S. Hurst, S-S. Sheu. Thomas Jefferson Univ.
B170 960.7
High Density Lipoprotein-Lipopolysaccharide
Binding Lowers HDL’s Basal Antioxidant Capacity. D.W.
Fausnacht, N.E. Boutagy, R.P. McMillan, M.W. Hulver.
Virginia Tech and Yale Sch. of Med.
961. CARDIOVASCULAR AND RENAL MECHANISMS
IN DIABETES AND METABOLIC SYNDROME
Poster
Exhibit Halls A-D
B171 961.1
High Fat Diet-Induced Obesity Does Not
Necessarily Promote Vascular Remodeling/Fibrosis in Rats.
R. Fernandes, E. Carter-Taylor, J. Galligan, H. Xu. Michigan
State Univ.
B172 961.2
Protein Tyrosine Phosphatase 1B Deficiency
in Pro-opiomelanocortin Neurons Does Not Enhance Leptin’s
Anorexigenic Effect, but Improves Glucose Tolerance and
Increases Energy Expenditure in Mice Fed a High Fat Diet.
N. Aberdein, J.M. do Carmo, J.E. Hall. Univ. of Mississippi
Med. Ctr.
B173 961.3
Hydrogen Sulfide Suppresses Diabetic
Myocardial ER Stress: An Uncanonical Way. S. Veeranki, N.
Metreveli, S.C. Tyagi. Univ. of Louisville.
B174 961.4
Deletion of the Formin, Drf1, Is Protective
against Renal Damage in a Murine Model of Diabetes. M.B.
Manigrasso, R. Rosario, R. Ramasamy, V. D’Agati, A.M.
Schmidt. NYU Langone Med. Ctr. and Columbia Univ. Col. of
Physicians and Surgeons.
B175 961.5
Continuous Glucose Measurements Using
Telemetry in Male and Female Dahl Salt-Sensitive Rats on a
High-Fat Diet. E. Gillis, E. Ralph, S. Tiesma, R. Lindquist, J.
Sullivan. Georgia Regents Univ. and Data Sci. Intl., MN.
962. NEURAL AND HORMONAL MODULATION OF
FLUID BALANCE AND ION HOMEOSTASIS IN
HEALTH AND DISEASE
Poster
Exhibit Halls A-D
B176 962.1
Vasopressin
Receptor
Regulation
in
Maintaining Potassium Homeostasis in a Sus scrofa Model
of Hemorrhagic Shock. C.F.T. Uyehara, L.N. Kajiura, L-A.M.
Murata, S.A. Wong, W.M. Ichimura, C.A. Hernandez, J.
Sarkar, M.R. Rowland. Tripler Army Med. Ctr., HI.
B177 962.2
Chronic Insulin-Clamp Causes Postprandial
Diuresis in Sprague Dawley Rats. D.L. Irsik, R. Alaisami, A.R.
Washington, M.W. Brands. Georgia Regents Univ.
B178 962.3
Renal Afferent Nerve Modulation of Sodium
Homeostasis and Blood Pressure: A Sodium Sensitive
Mechanism Countering the Development of Salt-Sensitive
Hypertension? R.D. Wainford, K.R. Walsh, C.Y. Carmichael.
Boston Univ.
B179 962.4
Preserved Survival of Renal Tubulus-Specific
Sodium Hydrogen Exchanger Isoform 3 Knockout Mice in
Response to Sodium Restriction. S. Chavez, S.B. Poulsen,
M. Soleimani, R.A. Fenton, T. Rieg. UCSD and VA San
Diego Healthcare Syst., Aarhus Univ., Denmark and Univ. of
Cincinnati and VA Med. Ctr.
B180 962.5
High Salt Activation of Collecting Duct-Derived
Nitric Oxide Synthase Suppresses the Renin-AngiotensinAldosterone System. J.S. Pollock, D.M. Pollock, C. Dugas,
K.A. Hyndman. Univ. of Alabama at Birmingham.
B181 962.6
Salt and Angiotensin II Treatment Induces
Fluid Congestion and Heart Failure with Increased Mortality
in Balb/C Mice but Not in C57BL/6J. S.T. Joensson, M.
Becriovic-Agic, M. Hulström. Uppsala Univ.
B182 962.7
Chronic Vagus Nerve Stimulation Attenuates
Renal Inflammation in Autoimmune-Induced Hypertension.
G.S. Pham, A.S. Fairley, C.I. Maloy, K.W. Mathis. Univ. of
North Texas Hlth. Sci. Ctr.
B183 962.8
Median Preoptic AT1a Receptor Knockdown
Does Not Diminish Drinking in Response to Peripheral
Angiotensin II Administration. B. Shell, G. Farmer, R. Emeh, J.
Little, T. Cunningham. Univ. of North Texas Hlth. Sci. Ctr. and
Alabama State Univ.
B184 962.9
Renal Denervation Normalizes Blood Pressure
and Improves Glucose Metabolism in Obese Genetically
Hypertensive Schlager Mice. N. Asirvatham-Jeyaraj, C.T.
Banek, R. Han, M. Razzoli, B.J. Burbach, A. Bartolomucci,
Y. Shimizu, J.W. Osborn. Univ. of Minnesota, Minneapolis.
963. SEX DIFFERENCES IN BLOOD PRESSURE AND
FLUID VOLUME HOMEOSTASIS
Poster
Exhibit Halls A-D
B185 963.1
Renal Salt and Water Homeostasis: A New
Regulatory Pathway Involving the Ser/Thr Kinase PIM-3
A. Spirli, C. Ronzaud, A. Debonneville, O. Staub. Univ.
of Lausanne.
B186 963.2
Identification of Dipeptidyl Peptidase III as
the Angiotensin-(1-7)-Degrading Metallopeptidase in Human
Proximal Tubule Cells. N. Cruz-Diaz, B.A. Wilson, A.C.
Marshall, N.T. Pirro, M.C. Chappell. Wake Forest Sch. of Med.
B187 963.3
Deficiency of Prorenin Renin Receptor in
Adipocyte Induces Liver Steatosis and Increases Blood
Pressure in Lean and Obese Male Mice. C-H. Wu, S. Moradi,
M. Gong, G. Nguyen, F. Yiannikouris. Univ. of Kentucky and
Col. de France, Paris.
B188 963.4
The Predominant Role of Kidney in Sex
Difference in Ang II-Induced Hypertension. L. Wang, R. Chen,
J. Zhang, S. Rong, S. Wang, J. Wei, K-P. Yip, R. Liu. Univ. of
South Florida and Hannover Med. Sch., Germany.
B189 963.5
Physiological and Transcriptomic Data Have
Equal Variability in Male and Female Rats. A. Dayton, M.
Skelton, M. Kaldunski, A.S. Greene, A.W. Cowley; Jr.
B190 963.6
Blood Pressure in Old Female SHR Is Not Salt
Sensitive and Tempol Fails to Decrease Blood Pressure during
High Salt Intake. C. Dalmasso, R.O. Maranon, C.N. Patil, J.F.
Reckelhoff. Univ. of Mississippi Med. Ctr.
317
M
O
N
PHYSIOLOGYMONDAY
964. HYPERTENSION: DEVELOPING CONCEPTS
Poster
Exhibit Halls A-D
B191 964.1
Does Chronic Inhibition of Brain Endoplasmic
Reticulum Stress Alter Metabolic and Cardiovascular Function
in Obese Melanocortin-4 Deficient Rat? J.M. do Carmo, A.A.
da Silva, J. Yoo, S.P. Moak, F. Spradley, J.E. Hall. Univ. of
Mississippi Med. Ctr. and Org. Educ. Barao de Maua, Ribeirão
Preto, Brazil.
B192 964.2
Endothelial-Derived Endothelin-1 Distinctly
Mediates the Development of Renal Apoptosis in Male and
Female Mice. C. De Miguel, K.D. Battles, W.C. Hamrick, X. Liu,
D.M. Pollock, J.S. Pollock. Univ. of Alabama at Birmingham.
B193 964.3
Activated
Immune
Cells
Exacerbate
Angiotensin II-Induced Hypertension and Renal Damage in
the Dahl Salt-Sensitive Rat. B.M. Wade, D. Mattson. Med. Col.
of Wisconsin.
B194 964.4
Mycophenolate
Mofetil
Attenuates
Hypertension in an Experimental Model of Systemic Lupus
Erythematosus. E. Taylor, A. Strawder, M. Ryan. Univ. of
Mississippi Med. Ctr.
B195 964.5
A high Fat Diet Increases Blood Pressure
and Leads to a Renal Proinflammatory Immune Cell Profile
in Female Dahl Salt-Sensitive Rats. L. Taylor, J. Musall, B.
Baban, E.J. Belin de Chantemele, J. Sullivan. Georgia
Regents Univ.
B196 964.6
Improvement in Blood Pressure and Renal
Injury following Vagal Nerve Stimulation. C.I. Maloy, A.S.
Fairley, G.S. Pham, K.W. Mathis. Univ. of North Texas Hlth.
Sci. Ctr.
B197 964.7
Hemodynamic Mechanisms of Renal Injury
in Dahl SS Rats Fed a High Salt Diet. A. Polichnowski, K.
Griffin, P. Sethupathi, M. Picken, J. Long, G. Williamson, A.
Bidani. Hines VA Hosp. and Loyola Univ.-Chicago and Illinois
Inst. of Technol.
B198 964.8
Radiofrequency Renal Denervation Decreases
Inflammation in Kidney Medulla in Spontaneously Hypertensive
Rats. J. Gao, L. Xiao, D.J. Polhemus, F. Smart, R. Mernaugh,
T.T. Goodchild, D.J. Lefer, D.G. Harrison, D.R. Kapusta. LSU
Hlth. Sci. Ctr. New Orleans and Vanderbilt Univ.
B199 964.9
Sex-Specific Cell Death Response following
Renal Ischemia-Reperfusion in Spontaneously Hypertensive
Rats. G.R. Crislip, J.C. Sullivan. Georgia Regents Univ.
B200 964.10 Endothelial-Derived ET-1 Contributes to the
Pressor Response Elicited by Acute Behavioral Stress. B.M.
Fox, A.S. Loria, K.A. Hyndman, R. Johns, C. Jin, D.M.
Pollock, M. Yanagisawa, J.S. Pollock. Univ. of Alabama at
Birmingham, Univ. of Kentucky, Georgia Regents Univ. and
Univ. of Tsukuba, Japan.
B201 964.11 Microbial Short Chain Fatty Acid Metabolites
Lower Blood Pressure via Endothelial G-Protein Coupled
Receptor 41 N. Natarajan, D. Hori, S. Flavahan, J. Steppan,
N.A. Flavahan, D.E. Berkowitz, J.L. Pluznick. Johns
Hopkins Univ.
B202 964.12 Evidence for Endothelin Regulation of Bmal1
Expression in the Renal Vasculature. D. Chen, J.S. Speed,
K.A. Hyndman, M. Kasztan, J.J. Johnston, E.W. Inscho,
M.E. Young, D.M. Pollock, J.S. Pollock. Univ. of Alabama
at Birmingham.
318
B203 964.13 The Role of Gαi2 Proteins in the Regulation
of PVN Neuronal Activation in Response to Isotonic Volume
Expansion in Conscious Rats. C.Y. Carmichael, N.M. Patel,
R.E. Wipfler, R.D. Wainford. Boston Univ. Sch. of Med.
B204 964.14 RhoBTB1, a Novel PPARγ Target Gene
Regulates Vascular Function. M. Mukohda, S-R.C. Ibeawuchi,
C. Hu, F.W. Quelle, C.D. Sigmund. Univ. of Iowa and California
Inst. for Biomed. Res., La Jolla.
B205 964.15 Leptin-Mediated Increases in Sympathetic
Tone Decreases Alpha(1D)-Adrenergic Receptor Expression
in Arteries and Adrenals. M. Newell, M. Momtahan, S.
Kennard, E.J. Belin de Chantemele. Med. Col. of Georgia at
Augusta Univ.
B206 964.16 ACE2 Deletion Is Associated with Increased
ADAM17 and Reduced Inhibitory Currents to Pre-sympathetic
Hypothalamic Neurons. S. Mukerjee, J. Xu, S. Sriramula,
H. Gao, A. Zsombok, E. Lazartigues. LSU Hlth. Sci. Ctr.,
New Orleans.
B207 964.17 Flow-Induced Activation of NO Production Is
Calcium- and HDAC1-Dependent in Inner Medullary Collecting
Duct Cells. R.S. Sedaka, K.A. Hyndman, J.S. Pollock. Univ.
of Alabama at Birmingham.
965. KIDNEY IN HYPERTENSION
Poster
Exhibit Halls A-D
B208 965.1
Both Alpha and Beta Adrenergic Receptor
Expression Is Increased in the Renal Medulla of Spontaneously
Hypertensive African Green Monkeys. M.K. Rhoads, C.
Munhoz, J. Osborn. Univ. of Kentucky and Fed. Univ. of
Pelotas, Brazil.
B209 965.2
Effect of Low-Dose of Multi-glycoside of
Tripterygium wilfordii Hook. F. on Renal Injury in Mice with SaltSensitive Hypertension. Y. Wang, C. Song, M. Zhu, H. Xu, X.
Wang, L. Cui, S. Liu, S. Xie, S. Shen, S. Zhang, D.H. Wang.
Henan Univ. of Traditional Chinese Med., China and Michigan
State Univ.
B210 965.3
Conscious Dahl Salt-Sensitive Rats Excrete
a Volume Load Slower Than Sprague Dawley Rats Due to a
Defect in Thick Ascending Limb Transport. F. Saez, J. Garvin.
B211 965.4
Exposure to Cigarette Smoke Worsens
Chronic Kidney Disease-Induced Cardiac Hypertrophy and
Fibrosis. C.A. Drummond, D.A. Hernandez, S.T. Haller, J.
Liu, J.I. Shapiro, C.J. Cooper, J. Tian. Univ. of Toledo and
Joan C. Edwards Sch. of Med., Marshall Univ.
B212 965.5
Vascular Endothelial Growth Factor Down
Regulates the Renal Epithelial Sodium Channel. A. Koenen,
R. Rettig, O. Grisk. Univ. of Greifswald, Germany.
B213 965.6
Neddylation-Deficient K712R CUL3 Δ403-459
Double Mutant Attenuates Proteasome-Dependent KLHL3
Degradation. R.J. Cornelius, C. Zhang, K.J. Erspamer, A.S.
Terker, J.D. Singer, C-L. Yang, D.H. Ellison. Oregon Hlth. &
Sci. Univ., Xinhua Hosp., Sch. of Med., Shanghai Jiao Tong
Univ., China, Portland State Univ. and Portland VA Med. Ctr.
MONDAYPHYSIOLOGY
B214 965.7
Lack of Collecting Duct Renin Does Not
Protect against DOCA-Salt Hypertension and Renal Injury. K.
Song, D. Stuart, N. Abraham, F. Wang, S. Wang, T. Yang, C.D.
Sigmund, D.E. Kohan, N. Ramkumar. Univ. of Utah, Univ. of
Iowa and VA Salt Lake City Hlth. Care Syst.
B215 965.8
NEDD4-2 Reduces Electroneutral Cl-/HCO3Exchange in Mouse Cortical Collecting Duct. T.D. Pham, M.
Nanami, O. Staub, R.L. Sutliff, J.D. Klein, D. Eladari, R.
Chambrey, X. Wang, J.W. Verlander, S.M. Wall. Emory Univ.,
Hyogo Col. of Med., Japan, Univ. of Lausanne, Inst. des
Cordeliers, Paris and Univ. of Florida.
B216 965.9
Zinc Deficiency Stimulates Sodium Chloride
Cotransporter Upregulation via Modulation of Calcineurin
Activity in Mouse Distal Convoluted Tubular Cells. C.R.
Williams, M. Mistry, M. Li, B. Ko, J.L. Gooch, R.S. Hoover.
Emory Univ., Atlanta VA Med. Ctr., Decatur, Univ. of Chicago
and Philadelphia Col. of Osteo. Med., Sch. of Pharm.,
Suwanee, GA.
B217 965.10 G Protein-Coupled Estrogen Receptor
Expression in the Kidney of L-NAME-Induced Hypertension
and 2K-1C Rats. E. Barbosa de Oliveira Sales, N. Oliveira
Maruyama, V. Araujo Varela, T.F. Lucas, M.A. Boim, C.
Segreti Porto, C. Toledo Bergamaschi, R. Ribeiro de
Campos Jr. Fed. Univ. of São Paulo.
B218 965.11 Alstrom Syndrome 1, a New Interacting
Protein of NKCC2, Regulates Apical NKCC2 Trafficking,
Urinary Concentration and Blood Pressure. A.B. Jaykumar, P.
Caceres, G. Ares, W. Beierwaltes, P. Ortiz. Henry Ford Hosp.
and Wayne State Univ.
B219 965.12 Stem Cells Improved the Ability of the
Contralateral Kidney to Excrete Sodium in the Renovascular
Hypertension Induced by Renal Artery Stenosis. V. Araujo
Varela, E. Barbosa de Oliveira-Sales, C. Gusson Shimoura,
E. Maquigussa, F. Teixeira Borges, M.A. Boim. Fed. Univ. of
São Paulo.
B220 965.13 Dopamine β-Hydroxylase Inhibition with
BIA5-1058 Normalizes the High Blood Pressure of Human
GRK4g 142V Transgenic Mice. L.D. Asico, H. Lin, J.E.
Jones, P. Soares-da-Silva, P.A. Jose, X. Wang. George
Washington Univ., Univ. of Maryland at Baltimore and Univ. of
Porto, Portugal.
B221 965.14 ETA Receptor Antagonism and Estrogen
Replacement Prevent Ang II Hypertension in Menopausal
Mice. D.P. Pollow; Jr, M.J. Romero-Aleshire, J. Davies, J.
Nikolich-Zugich, H.L. Brooks. Univ. of Arizona.
B222 965.15 Altered Renal and Circulating ReninAngiotensin System Does Not Cause Spontaneous
Hypertension in the African Green Monkey. A. Gutierrez, S.B.
Goleva, M.K. Rhoads, C.C. Weaver, W.H. Beierwaltes, J.L.
Osborn. Univ. of Kentucky, Henry Ford Hosp. and Biomed.
Sci. Res. Gp., Lexington.
B223 965.16 Renal Specific Downregulation of OXPHOS
Transcription Factors and Mitochondrial Respiratory
Dysfunction in Spontaneously Hypertensive Nonhuman
Primates. S. Goleva, M. Rhoads, J. Osborn. Univ. of Kentucky
and Biomed. Sci. Res. Gp. LLC, Lexington.
B224 965.17 Salt Inducible Kinase: A Potential Intracellular
Signal Involved in DOCA-Salt Induced Hypertension? S.R.
Gonsalez, F.M. Ferrão, D.S. Gomes, D.G.B. de Lima, J.
Lowe, M.C. Prieto, L.S. Lara. Tulane Univ., Rio de Janeiro
State Univ. and Fed. Univ. of Rio de Janeiro.
966. IMMUNE CELLS AND INFLAMMATION IMPACT
ON KIDNEY FUNCTION AND HYPERTENSION
Poster
Exhibit Halls A-D
B225 966.1
Meprin β Deficiency Reduces Leukocytes
Infiltration in Mouse Kidneys with Unilateral Ureteral
Obstruction-Induced Inflammation. M.C. Fernander, J-M.V.
Niyitegeka, D. Conklin, I. Yahaya, R.C. Minor, E.M. Ongeri.
North Carolina A&T State Univ.
B226 966.2
Formyl Peptide Receptor Blockade Ameliorates
Intrarenal Resistance Artery Function and Decreases Blood
Pressure in SHR. C.F. Wenceslau, C.G. McCarthy, T. Szasz,
S. Ogbi, R.C. Webb. Georgia Regents Univ.
B227 966.3
Transferrin Receptor Levels Are Increased by
Interleukin 1β in a Human Kidney Proximal Tubular Cell Line.
M.L. Bonnemaison, E.I. Boesen. Univ. of Nebraska Med. Ctr.
B228 966.4
T Cell Infiltration in Kidney Induces SaltRetention via NCC Up-Regulation. S. Mu, Y. Liu. Univ. of
Arkansas for Med. Sci.
B229 966.5
Intervention with VG1177, a MHC Class
II Invariant Peptide Chain Antagonist, Restores Afferent
Arteriolar Autoregulatory Behavior during Chronic 14 Day
Lipopolysaccharide Treatment. J.P. Van Beusecum, A.K.
Cook, S. Zhang, R.P. Tobin, K. Newell-Rogers, E.W. Inscho.
Univ. of Alabama at Birmingham and Texas A&M Hlth. Sci. Ctr./
Baylor Scott & White Hlth.
B230 966.6
Interleukin-6
Receptor
Alpha
Exhibits
Differential Cellular Localization within the Nephron. T.A. Kronk,
F. Theilig, O. Al-Khalili, R. Mallick, D.C. Eaton, R.S. Hoover,
B.M. Wynne. Emory Univ., Univ. of Fribourg, Switzerland and
Atlanta VA Med. Ctr., Decatur.
B231 966.7
RORγt-Dependent Preferential Induction of
IL-17F by TLR3 Activation in SHR Immune Cells. M.V. Singh,
M.Z. Cicha, M.W. Chapleau, F.M. Abboud. Univ. of Iowa and
VA Med. Ctr.
B232 966.8
Bicarbonate Therapy Has No Effect on Renal
T-Cell Infiltration or Blood Pressure but Markedly Reduces
Tubular Casts/Fibrosis and Is Associated with an M1 to M2
Polarization in Dahl Salt-Sensitive Rats. P. O’Connor, J-K.
Chen, L. Taylor, S. Ray, B. Baban, J.C. Sullivan. Georgia
Regents Univ.
B233 966.9
SH2B3 Mutation Attenuates T Lymphocyte
Intracellular Ca2+ Release in Response to Direct Angiotensin-II
Stimulation in Dahl S Hypertensive Rats. G. Blass, O. Palygin,
N.P. Rudemiller, D. Mattson, A. Staruschenko. Med. Col.
of Wisconsin.
B234 966.10 Suppressing Hypertension Preserves Renal
Autoregulatory Behavior and Purinoceptor Response in
Deoxycorticosterone Acetate-Salt-Treated Rats. Z. Guan,
H. Cha, J.P. Van Beusecum, A.K. Cook, E.W. Inscho. Univ.
of Alabama at Birmingham and Sch. of Nat. Sci, Univ. of
California, Merced.
319
M
O
N
PHYSIOLOGYMONDAY
967. RENAL TRANSPORT MECHANISMS
Poster
Exhibit Halls A-D
B235 967.1
Hydrochlorothiazide
Does
Not Acutely
Acidify Urine. P. de Bruijn, R. Brekelmans, H. Praetorius, J.
Leipziger. Aarhus Univ., Denmark.
B236 967.2
Localization and Regulation of the DiseaseCausing H+-ATPase B1 Subunit in the Early Distal Nephron
of Human and Murine Kidney. H. Dimke, R. Chambrey, R.
Zamani, N. Marcussen, P. Svenningsen, S. Frische. Univ. of
So. Denmark, Univ. Paris-Descartes, Odense Univ. Hosp. and
Univ. of Aarhus, Denmark.
B237 967.3
A Novel GPCR in the Renal Proximal Tubules,
Gprc5c, Is Involved in Systemic pH Regulation. P. Rajkumar,
B. Cha, M. Donowitz, Y. Hirabayshi, J.L. Pluznick. Johns
Hopkins Sch. of Med. and RIKEN Brain Sci. Inst., Saitama.
B238 967.4
Effect of NBCe1 Deletion on Renal Organic
Anion Metabolism. I.D. Weiner, G. Osis, M.E. Handlogten,
H-W. Lee, K. Hering-Smith, M.F. Romero, J.W. Verlander.
Univ. of Florida, NF/SG Veterans Hlth. Syst., Tulane Univ. and
Mayo Clin.
B239 967.5
Internalization of Angiotensinogen in Renal
Proximal Tubules: Evidence for Mitochondrial Trafficking. B.
Wilson, N. Cruz-Diaz, Y. Su, J.C. Rose, M.C. Chappell. Wake
Forest Sch. of Med.
B240 967.6
Lack of an Effect of Collecting Duct-Specific
Knockout of Nitric Oxide Synthase 3 on Renal Sodium and
Water Excretion or Blood Pressure during Physiological
Conditions. Y. Gao, D. Stuart, T. Takahashi, D. Kohan. Univ. of
Utah and Vanderbilt Univ.
B241 967.7
Evidence of Phosphodegron Regulating
Expression of Urate Secretory Transporter ABC. G2 O.M.
Woodward, A. Hofherr, Q. Huang, M. Kottgen. Univ. of
Maryland Sch. of Med. and Univ. Med. Ctr. Freiburg, Germany.
B242 967.8
Distinct Regulation of the Basolateral
Conductance in the Collecting Duct by Na+ and K+ Intake. O.
Zaika, V. Tomilin, M. Mamenko, O. Pochynyuk. Univ. of Texas
Hlth. Sci. Ctr. at Houston.
B243 967.9
Nitric Oxide Regulates Paracellular Resistance
in Isolated, Perfused Rat Thick Ascending Limbs through cGMP.
C.M. Monzon, J.L. Garvin. Case Western Reserve Univ.
B244 967.10 Targeted Knockin of Constitutively Active
SPAK in the Early Distal Convoluted Tubule (DCT1) Causes
Hyperkalemic Hypertension. P.R. Grimm, R. Coleman, E.
Delpire, P.A. Welling. Univ. of Maryland Sch. of Med. and
Vanderbilt Univ. Med. Sch.
B245 967.11 Determining the Kinetic Mechanism of
Metformin and NBD Interaction at the Multidrug Transporter
OCT2: A Mathematical and Experimental Approach. P.J.
Sandoval, T.W. Secomb, S.H. Wright. Univ. of Arizona.
B246 967.12 Role of the Novel Kinase TNIK on NKCC2
Surface Expression, Phosphorylation and Na Reabsorption
in the Thick Ascending Limb. P.S. Caceres, P.A. Ortiz. Henry
Ford Hosp. and Wayne State Univ.
B247 967.13 P2X Receptor-Mediated Inhibition of NaCl
Absorption in the Thick Ascending Limb: No Evidence for Nitric
Oxide as Second Messenger. S.L. Svendsen, J.S. Olsen, H.
Preatorius, J.G. Leipziger. Aarhus Univ., Denmark.
320
B248 967.14 The cGMP/PKG Signaling Pathway Underlies
the Inhibitory Effect of Sildenafil Citrate on NHE3 Activity in Rat
Renal Proximal Tubules. P.M.C. dos Santos, T.D. Pessoa, G.
Malnic. Univ. of São Paulo.
B249 967.15 Angiotensin II Increases Phosphorylation of
Rat Kidney Na, K-Pump at S938 in Proximal Tubule (PCT)
Cells through a Phosphatidylinositol 3’-Kinase/Akt Pathway
Facilitated via Epac. D.R. Yingst, R.R. Mattingly, S.M. Keezer.
Wayne State Univ. and Cell Signaling Technol., Danvers, MA.
B250 967.16 Short-Term Regulation of SGLT2 by Insulin
In Vivo. C. Ghezzi, C. Scafoglio, J. Liu, J.R. Barrio, E.M.
Wright. UCLA.
B251 967.17 Expression of a Diverse Array of Ca2+-Activated
K+ Channels Are Functionally Coupled to the Mechanosensitive
TRPV4 Channel in the Late Distal Tubule. Y. Li, H. Hu, R.G.
O’Neil. Univ. of Texas Hlth. Sci. Ctr at Houston.
B252 967.18 A Renal Olfactory Receptor Aids in Kidney
Glucose Handling. B.D. Shepard, L. Cheval, H. Koepsell,
A. Doucet, J.L. Pluznick. Johns Hopkins Univ. Sch. of Med.,
Sorbonne Univs. UPMC, Paris and Univ. of Wurzburg.
B253 967.19 Rapid Internalization and Trafficking of GC-A/
NPRA via Endo-lysosomal Compartments with Concurrent
Generation of cGMP in Mouse Mesangial Cells: Role of FQQI
Motif. I. Mani, R. Garg, S. Tripathi, K.N. Pandey. Tulane Univ.
Hlth. Sci. Ctr. and Sch. of Med.
B254 967.20 AT2R Is Involved in Mediating the Effect of High
Dietary K Intake on Basolateral Kir4.1 in the Distal Convoluted
Tubule. P. Wu, Z. Gao, M. Wang, X-T. Su, L. Wang, W-H. Wang.
New York Med. Col.
B255 967.21 Role of IGF1R in Tubular Remodeling of the
Mouse Kidney. E. Walczak, A. Krauson, S. Iyer, J. Nizar, W.
Dong, V. Bhalla. Stanford Univ.
B256 967.22 Dose-Dependent Effects of Angiotensin-(1-7)
and Angiontensin II on the NHE3 Exchanger in In Vivo Proximal
Tubule of Spontaneously Hypertensive Rats. R.C. Castelo
Branco, D.C.A. Leite-Dellova, G. Malnic, M. Mello-Aires.
Univ. of São Paulo.
B257 967.23 AMPK Stimulates Osmotic Water Permeability
in Rat IMCDs. Y. Wang, O. Efe, L.M. LaRocque, J.D. Klein,
J.M. Sands. Emory Univ.
B258 967.24 Effect of Oleanolic Acid on Regulation of Renal
Function and Hormonal Balance in Hypertension Model. Y.M.
Ahn, Y.J. Lee, H.Y. Kim, R. Tan, M.C. Kho, B.H. Han, S.H.
Lee, H.S. Lee, K.W. Cho, H.S. Lee, D.G. Kang. Col. of Orient.
Med. and Prof. Grad. Sch. of Orient. Med., Wonkwang Univ.,
South Korea.
B259 967.25 Impaired Urinary Concentration in Car2
Deficient Mice. R.T. Alexander, D. Krishnan, E. Cordat. Univ.
of Alberta.
B260 967.26 1,2,3,4,6-Penta–O-Galloyl–β–D–Glucose
Ameliorates Renal Injury in Ischemia-Reperfusion Induced
Acute Renal Failure Rats. J.H. Park, Y.J. Lee, H.Y. Kim, J.J.
Yoon, M.C. Kho, S.H. Lee, H.S. Lee, X.J. Jin, H.S. Lee, D.G.
Kang. Col. and Professional Grad. Sch. of Oriental Med.,
Wonkwang Univ., South Korea.
B261 967.27 Transcription
Factor
Elf3
Mediates
Vasopressin-Regulated Aquaporin-2 Expression in Renal
Collecting Duct Cells. S-T. Lin, C-C. Ma, Y-F. Su, C-H. Yang,
S-C. Weng, C-H. Sun, S-L. Lin, M-J. Yu. Col. of Med. Natl.
Taiwan Univ.
B262 967.28 Vasopressin-Escape Does Not Involve Marked
Changes in the Ratio of Intercalated-to-Principal Cells in the
Cortical Collecting Duct. C-L. Chou, C.M. Ecelbarger, J.W.
Lee, M.A. Knepper. NHLBI, NIH and Georgetown Univ.
MONDAYPHYSIOLOGY
B263 967.29 Sexual Dimorphic Expression of Renal
Claudins, Water Channels and Transporters Accounts for the
Downstream Shift in Salt and Volume Reabsorption Along
the Nephron in Female versus Male Rats. L.C. Veiras, L. Pei,
A.S.L. Yu, A.A. McDonough. Keck Sch. of Med., Univ. of So.
California and Univ. of Kansas Med. Ctr.
B264 967.30 Sex Differences in Renal Sodium Transporter
Gene Expression. R.S. Patel, K. Solocinski, K. Cheng, M.L.
Gumz. Univ. of Florida.
B265 967.31 Conditional Knock-Down of Kidney-Specific
Klotho Gene Impairs Sodium Reabsorption by Downregulating
Epithelial Sodium Channel Expression. Q. Ali, Y. Lin, X. Wang,
Z. Sun. Univ. of Oklahoma Hlth. Sci. Ctr.
968. EPITHELIAL BIOLOGY AND TRANSPORT I
Poster
Exhibit Halls A-D
B266 968.1
Inducible Renal Tubule-Specific Insulin
Receptor Knockout Mice Have Decreased NCC-Mediated
Sodium Reabsorption and Reduced Sensitivity to
Mineralocorticoid-Induced Hypertension in Obesity and Insulin
Resistance. J.M. Nizar, E.M. Walczak, W. Dong, L. Bankir, V.
Bhalla. Stanford Univ. and Cordeliers Res. Ctr., INSERM, Paris.
B267 968.2
Salt-Losing Nephropathy in Mice with a Null
Mutation of Clcnkb. A. Grill, I.M. Schiessl, A. Hammer, H.
Castrop. Inst. of Physiol, Regensburg, Germany.
B268 968.3
Down-Regulation of Kir4.1 Eliminates the
Basolateral K Conductance in the Distal Convoluted Tubule
and Inhibits NCC Activity. X-T. Su, M-X. Wang, P. Wu, J.A.
McCormick, D.E. Ellison, W-H. Wang. New York Med. Col.
and Oregon Hlth. & Sci. Univ.
B269 968.4
Tight Junction Protein Abundance Is Altered
in Metformin-Treated Airway Epithelial Cells. K.K. Kalsi,
J.P. Garnett, E.H. Baker, D.L. Baines. St. George’s Univ. of
London and Newcastle Univ., U.K.
B270 968.5
Hydrocortisone
Affects
the
Transport
Phenotype of Differentiated Normal Human Bronchial Epithelial
Cells. N. Zaidman, A. Panoskaltsis-Mortari, S.M. O’Grady.
Univ. of Minnesota, Minneapolis and St. Paul.
B271 968.6
Impact of Phosphorylation Site Mutations on
Human Amino Acid Uniporter LAT4 Expression, Localization
and Function. L. Oparija, A. Guetg, F. Verrey. Univ. of Zürich.
B272 968.7
Acute Pancreatitis Involves Alterations in the
Transport of Amino Acids Necessary for Glutathione Synthesis.
E. Kuster, R. Graf, F. Verrey, S.M. Camargo. Univ. of Zurich
and Univ. Hosp. Zurich.
B273 968.8
Stretch-Regulated Tight Junction Dynamics,
and Paracellular Permeability of the Urothelium. A.F. Eaton,
D.R. Clayton, W.G. Ruiz, G.L. Apodaca. Univ. of Pittsburgh.
B274 968.9
Smoking-Induced Urothelial Cell Accumulation
of Platelet-Activating Factor: Implications for Interstitial Cystitis/
Bladder Pain Syndrome. J. McHowat, J. Marentette, T.S.
Isbell, E.C. Campian. Saint Louis Univ.
B275 968.10 A Gut Microbial Metabolite of Linoleic Acid
and Gut Homeostasis. J. Miyamoto, S. Kishino, T. Suzuki,
J. Ogawa, I. Kimura, S. Tanabe. Hiroshima Univ., Kyoto Univ.
and Tokyo Univ. of Agr. and Technol.
B276 968.11 Xenin Induces Anion Secretion via Neural
Pathway in Rat Duodenum. I. Kaji, Y. Akiba, J.D. Kaunitz.
UCLA, Brentwood Biomed. Res. Inst. and West Los Angeles
VA Med. Ctr.
B277 968.12 Extreme Blood Pressure Polymorphisms
Influence the Bicarbonate-Independent Conductance of
NBCn1 but Not Its Na/HCO3 Cotransport Activity. F.J. Moss, B.
Zeise, M.D. Parker, B. Yu, A.C. Morrison, W.F. Boron. Case
Western Reserve Univ., Univ. at Buffalo and Univ. of Texas
Hlth. Sci. Ctr. at Houston.
B278 968.13 Differential Mechanisms of Ammonia Transport
in Rat Duodenum and Colon. Y. Akiba, I. Kaji, H. Said, J.D.
Kaunitz. UCLA and West Los Angeles VA Med. Ctr.
B279 968.14 Chronic Lithium Treatment Induces Novel
Patterns of Pendrin Localization and Expression in the Renal
Inner Medulla. N.J. Himmel, Y. Wang, D.A. Rodriguez, M.A.
Sun, M.A. Blount. Emory Univ.
B280 968.15 Basolateral Cholesterol Depletion of mpkCCD
Cells Results in Ubiquitylation of Aquaporin-2 C.H. Fuglsang,
R.A. Fenton, H.B. Moeller. Aarhus Univ., Denmark.
B281 968.16 Involvement of Bile Acids in Regulation of
Water Channel Expression in Colon Epithelial Cells. J. Yde,
H.B. Moeller, P. Dalsgaard, R.A. Fenton. Aarhus Univ. and
Randers Regional Hosp., Denmark.
B282 968.17 SGLT1 and Osmotic Water Flow across the
Small Intestine. K. Her, E. Gorraitz, D. Loo, E.M. Wright. UCLA.
B283 968.18 Insights into the Role of Occluding Septate
Junctions in the Maintenance of Salt and Water Balance in
Mosquito (Aedes aegypti) Larvae. S. Jonusaite, S.P. Kelly, A.
Donini. York Univ., Canada.
B284 968.19 AQP1 in Peritoneal Dialysate as Predictive
Biomarker of Integrity of the Peritoneal Barrier and Ultrafiltration
Efficiency. G. Procino, M.C. Nicoletti, S. Corciulo, R.
Corciulo, R. Russo, G. Grandaliano, M. Carmosino, M.
Svelto, L. Gesualdo. Univ. of Bari, Univ. of Foggia and Univ. of
Basilicata, Italy.
B285 968.20 Urinary Excretion of Kidney Aquaporins as
Possible Biomarker of Diabetic Nephropathy. G. Procino, L.
Rossi, M.C. Nicoletti, M. Carmosino, A. Di Franco, F. Indrio,
R. Lella, L. Laviola, L. Gesualdo, M. Svelto. Univ. of Bari and
Univ. of Basilicata.
B286 968.21 Ablation of the Renal Urea Transporters UTA1 and UT-A3 Replicates the Benefits of a Low-Protein Diet in
Attenuating Diabetic Nephropathy. Y. Wang, N.J. Himmel, G.M.
Mallow, M.A. Sun, M.R. Borchart, M.A. Blount. Emory Univ.
B287 968.22 Role of Catestatin in Intestinal Epithelial
Cell Turnover and Glucose Uptake in Hyperleptinemic Type
2 Diabetic Mice. C. Farrelly, S.K. Mahata, T. Rieg, J.A.
Dominguez Rieg. Bastyr Univ. California, UCSD and VA San
Diego Healthcare Syst.
B288 968.23 Do Compensatory Changes Occur in Intestinal
Glucose Transport following Gastric Bypass in Type 2, Diabetic
Rats. M. Hatch, B.K. Canales. Univ. of Florida.
B289 968.24 Regulation of Calcium Transport Pathways in
Kidney and Intestine during Lactation. H. Dimke, M.R. Beggs,
R.T. Alexander. Univ. of So. Denmark and Univ. of Alberta.
Receptor-1-Driven
B290 968.25 Protease-Activated
Intracellular Calcium Dynamics in Rat Glomerular Podocytes.
O. Palygin, D.V. Ilatovskaya, V. Levchenko, A. Staruschenko.
321
M
O
N
PHYSIOLOGYMONDAY
B291 968.26 TRMP4 Is Expressed in and Carries a
Nonselective Cation Current through the Apical Membrane of
Mouse Cortical Collecting Duct Principal Cells. M.M. Wu, T.L.
Thai, Y. Zhai, D.C. Eaton, Z. Zhang, H. Ma. Emory Univ. and
Harbin Med. Univ., China.
B292 968.27 Elevated Level of Hypoxia Inducible Factor
1α Can Alter Renal Epithelial Function. S.S. Nag, A. Resnick.
Cleveland State Univ.
B293 968.28 Cyclic-AMP Regulates Glycogen Synthase
Kinase-3β by a Feed-Forward Mechanism in Polycystic Kidney
Disease. V.R. Kakade, S. Tao, X. Zhou, X. Li, P. Pandey, M.
Rajagopal, R. Rao. Univ. of Kansas Med. Ctr.
B294 968.29 Remodeling of the Purinergic Receptors
Profile in the ARPKD Cystic Epithelia. D. Ilatovskaya, O.
Palygin, V. Levchenko, T. Pavlov, A. Staruschenko. Med.
Col. of Wisconsin.
969. CELL SIGNALING: PROTEINS, PATHWAYS,
AND MECHANISMS
Poster
Exhibit Halls A-D
B295 969.1
Dehydration Impairs Synaptic Plasticity
by Interfering with Late-Phase Long-Term Potentiation. A.
Vashisht, M. Morykwas, A. Hegde, L. Argenta, M. McGee.
Wake Forest Univ. Med.Sch.
B296 969.2
Screening Bioactivity of Virus Surface
Glycoprotein Peptides Using C. elegans Electropharyngiogram.
J.B. Hincks, B.B. Monrean, B. Lu, B.E. Taylor, K. Hueffer,
M.B. Harris. Univ. of Alaska Fairbanks and West Valley
H.S., Fairbanks.
B297 969.3
The First Cellular Step for ChemotherapyInduced Peripheral Neuropathy after Vincristine Treatment May
Require Binding to Neuronal Calcium Sensor- 1 E. Viveros
Araque, L. Huynh, L. Nguyen, Y. Yang, J. Rengifo, B. Ehrich.
Univ. Icesi, Colombia and Yale Univ. Sch. of Med.
B298 969.4
The Intermediate Filament Cytoskeleton Is a
Target of Statins and Statin-Induced Cancer Cell Death. K.P.
Trogden, P. Kabiraj, N.T. Snider. Univ. of North Carolina at
Chapel Hill.
B299 969.5
Probing the Cell Cycle Significance of Cdt1
Phosphorylation at Novel Sites. R.S. Harris, D. Varma, J.G.
Cook. North Carolina A&T State Univ., Northwestern Univ. and
Univ. of North Carolina at Chapel Hill.
B300 969.6
Nuclear Lemur Tyrosine Kinase-2 Regulates
RNA Polymerase II Dependent Transcription in Prostate
Cancer. K. Shah, N. Bradbury. Rosalind Franklin Univ. of Med.
and Sci.
B301 969.7
Transcriptional Regulation of LMTK2, a Serine/
Threonine Kinase Implicated in Cystic Fibrosis. I. Dey, N.
Bradbury. Rosalind Franklin Univ. of Med. and Sci.
B302 969.8
The SH2 Domain of the Src Family Kinase FYN
Binds to Partitioning Defective Protein 3 (PARD3) K. Hinkle, A.
Haswell, B. Ballif. Norwich Univ. and Univ. of Vermont.
B303 969.9
Contribution of Oligomeric Forms of Tripartite
Motif E3 Ubiquitin Ligase Proteins to Plasma Membrane Repair
in Striated Muscle. L.V. Gushchina, J. Alloush, J.H. Choi, S.
Bhattacharya, E. Beck, N. Weisleder. The Ohio State Univ.
322
B304 969.10 PYY, a Novel Factor in Human Myogenesis.
B.J-F. Gheller, H. Roman, J. Blum, A. Thalacker-Mercer.
Cornell Univ.
B305 969.11 Effects of PYY on IL-6 Signaling in Primary
Human Myotubes. J.E. Blum, B.J.F. Gheller, H. Roman, A.
Thalacker-Mercer. Cornell Univ.
B306 969.12 Mutation in the PPARγ Ligand Binding Domain
Impairs the AntiiInflammatory Action of PPARγ M. Mukohda,
P. Ketsawatsomkron, M. Stump, X. Liu, D.F. Guo, K.
Rahmouni, F.W. Quelle, C.D. Sigmund. Univ. of Iowa and
Nortis Inc., Seattle.
B307 969.13 Toll-Like Receptor 4 Mutation Moderates
Hyperhomocysteinemia-Induced Hypertension. A. Familtseva,
P. Chaturvedi, A. Kalani, N. Metreveli, G.H. Kunkel, S.C.
Tyagi. Univ. of Louisville.
B308 969.14 Enhancement of Neutrophil Antimicrobial
Activity by the Breast Cancer Drug Tamoxifen. R. Flores, P.A.
Insel, V. Nizet, R. Corriden. UCSD.
B309 969.15 Domain of hCLCA1 That Is Responsible for
Macrophage Activation. J.C.H. Ching, M.E. Loewen. Univ.
of Saskatchewan.
B310 969.16 The Anti-inflammatory Peptide Ac-SDKP
Is Released from Thymosin β4 by Meprin α and Prolyl
Oligopeptidase. N. Kumar, P. Nakagawa, B. Janic, C.A.
Romero, M.E. Worou, E.L. Peterson, E.E. Ongeri, J-M.V.
Niyitegeka, N-E. Rhaleb, O.A. Carretero. Henry Ford Hosp.,
Detroit and North Carolina A&T State Univ.
B311 969.17 Absence of PKCα Alters the Renal Immune
Response in Angiotensin II-Dependent Hypertension. M.R.
Borchart, F.E. Pulous, Y. Wang, M.A. Sun, N.J. Himmel, T.H.
Vanderford, M.A. Blount. Emory Univ.
B312 969.18 Nox4 Regulates the mTor Signaling Pathway
in the Dahl Salt Sensitive Model of Hypertension. V. Kumar, A.
Staruschenko, A.W. Cowley; Jr.Med. Col. of Wisconsin.
B313 969.19 Involvement of the Cyclic AMP Pathway in
Dendritic Cell Regulation of Th2 Immune Responses. A.M.
Chinn, J. Lee, S. Herdman, E. Raz, P.A. Insel. UCSD.
B314 969.20 High Glucose Promotes the Pro-migratory
Phenotype of Retinal Pigment Epithelial Cells through
Increased Oxidative Stress. M. Farnoodian, C.M. Sorenson,
N. Sheibani. Univ. of Wisconsin-Madison.
B315 969.21 Deletion of Hepatic AMPK Leads to Metabolic
Inflexibility in Low- and High-Protein Diets but Not in Normoprotein Diet. T. Chalvon-Demersay, P.C. Even, C. Chaumontet,
J. Piedcoq, B. Viollet, C. Gaudichon, D. Tomé, M. Foretz, D.
Azzout-Marniche. AgroParisTech, INRA, Univ. Paris Saclay,
Inst. Cochin and Univ. Paris Descartes.
B316 969.22 The α2-Subunit of AMP-Activated Protein
Kinase Is a Potent Modulator of Myocardial Diastolic Calcium
Homeostasis. U. Pohl, E. Fein, P. Kameritsch, H. Schneider,
S. Engelhardt, A. Dendorfer, S. Blodow. Ludwig Maximilians
Univ., DZHK, Munich and Tech Univ. Munich.
B317 969.23 Role of Calcium Signaling for GDNF Secretion,
Ureter Branching and Early Nephron Formation. J.M. Fontana,
D. Unnersjö Jess, H. Blom, H. Brismar, A. Aperia. Royal Inst.
of Technol., Sci. for Life Lab. and Karolinska Inst., Stockholm.
B318 969.24 Epac-Mediated
Vasorelaxation:
Epac
Increases Spontaneous Transient Outward Current in
Mesenteric Artery Smooth Muscle via Activation of CAMKII. C.
Dart, E.S.A. Humphries. Univ. of Liverpool.
MONDAYPHYSIOLOGY
B319 969.25 Chenodeoxycholic Acid Initiates Distinct
Signaling Mechanisms to Stimulate Cl- Transport in Intestinal
and Non-Intestinal Epithelial Cells. J. Domingue, A. George,
M. Ao, M. Bijvelds, H. de Jonge, J. Sarathy, M.C. Rao. Univ.
of Illinois at Chicago, Erasmus MC, Rotterdam and Benedictine
Univ., IL.
B320 969.26 A Mathematical Model of Calcium and cAMP
Signaling in Pulmonary Microvascular Endothelial Cells. K.J.
Webb, C.A. Wiles, N. Annamdevula, R. Sweat, A.L. Britain,
A-V. Phan, M.I. Townsley, S.J. Leavesley, T.C. Rich. Univ. of
South Alabama.
B321 969.27 Hyperspectral Imaging Approaches for
Measuring Three-Dimensional FRET. N.S. Annamdevula,
R. Sweat, A. Britain, T.C. Rich, S.J. Leavesley. Univ. of
South Alabama.
B322 969.28 Loss of the Inhibitory G-Protein, Gz, Protects
against Type I Diabetes-Like Hyperglycemia by Stimulating
Islet Signaling Pathways That Promote Beta-Cell Function and
Survival. R.J. Fenske, M.T. Cadena, A.L. Brill, N.A. Truchan,
M.E. Kimple. Univ. of Wisconsin-Madison and William S.
Middleton Mem. Veterans Hosp.
B323 969.29 A-Kinase Anchoring Proteins Coordinate
the Contractile Phenotype of Airway Smooth Muscle. W.J.
Poppinga, B. Han, C.R. Elzinga, A.J. Halayko, H. Meurs, M.
Schmidt. Univ. of Groningen and Univ. Med. Ctr. Groningen,
Netherlands and Univ. of Manitoba.
B324 969.30 Bayesian Analysis of E3 Ubiquitin Ligase/
AQP2 Interactions in the Renal Collecting Duct. B.L. Medvar,
A. Sarkar, M. Knepper. NHLBI, NIH and The Catholic Univ.
of America.
B325 969.31 Functional Motif Discovery in Signaling Biology
Using a Deep Sequence-to-Structure-to-Function Analysis.
J.W. Prokop. HudsonAlpha Inst. for Biotechnol., AL.
B326 969.32 GPCRomic Analysis of Human Lung
Fibroblasts. A.V. Michkov, K. Sriram, N. Aroonsakool, P.A.
Insel. UCSD.
B327 969.33 N-Cadherin Adhesion Modulates RhoGTPase
Signaling to Promote Endothelial Barrier Integrity. K.J. Kruse,
F. Huang, S. Ying, S. Vogel, A. Malik, Y. Komarova. Univ. of
Illinois at Chicago.
B328 969.34 Elucidating the Dynamics of NanoparticleProtein Interaction at a Biomolecular Level: Structural and
Functional Studies Using Firefly Luciferase. S.E. Thomas, S.
Marroquin, R.K. DeLong. Missouri State Univ. and Kansas
State Univ.
970. CELL VOLUME, OSMOREGULATION, AND
WATER TRANSPORT
Poster
Exhibit Halls A-D
B329 970.1
MAp44: Diffusion from Blood to Cerebrospinal
Fluid and Intrathecal Synthesis. A.J. Dorta-Contreras, B.
Padilla-Cocal, I.M. Iglesias González, J.P. Martínez-Larrarte,
W. Castillo-González, C. González-Losada, J. GonzálezArgote, J.C. Jensenius. San Miguel Padron Hosp., Univ. of
Med. Sci. of Havanna and Aarhus Univ., Denmark.
B330 970.2
TRPC3 Serves as a Link between
Osmosensitivity and Water Transport in the Mouse Collecting
Duct. V. Tomilin, M. Mamenko, O. Zaika, O.M. Pochynyuk.
Univ. of Texas, Hlth. Sci. Ctr. at Houston and Inst. of Cytol.,
Russian Acad. of Sci., St. Petersburg.
B331 970.3
Lithium Induces Warburg-Like Proliferation
of Principal Cells in Lithium-Induced Nephrogenic Diabetes
Insipidus and Underlies Its Collecting Duct Remodeling. M.
Alsady, L. van der Tholen, J. Bedford, R. Walker, T. de Groot,
P. Deen. Radboud Univ. Med Ctr., Netherlands and Univ. of
Otago, New Zealand.
B332 970.4
Aquaporin 9 in the Freeze Tolerance
Mechanism of Cope’s Gray Treefrogs. B. Stogsdill, J. Frisbie,
D. Goldstein. Wright State Univ.
B333 970.5
The Osmotic H2O-Permeability of Human
Urea Transporters UT-A1, A2, A3 and B in Rana catesbeiana
Oocytes. J. Kabutomori, R.R. Geyer, R. Musa-Aziz. Univ. of
São Paulo.
971. PH HOMEOSTASIS AND ACIDBASE TRANSPORT
Poster
Exhibit Halls A-D
B334 971.1
Quantification of Red Blood Cell Size and
Shape in AQP1–/–, RhaG–/–, and Double-Knockout Mice. F.J.
Moss, P. Zhao, P.G. Woost, J.W. Jacobberger, W.F. Boron.
B335 971.2
Is the Electrogenic Na/HCO3 Cotransporter a
CO2 Channel? R. Occhipinti, J. Lu, W.F. Boron. Case Western
Reserve Univ. and Smilow Cancer Hosp. at Yale-New Haven.
B336 971.3
Exploring an Autoinhibitory Domain in the
Electrogenic Na/HCO3 Transporter NBCe1-B. S-K. Lee, W.F.
Boron. Case Western Reserve Univ.
B337 971.4
Stimulation of the Electrogenic Na/HCO3
Transporter NBCe1-B by Phosphomimetic Mutants of IRBIT.
S-K. Lee, W.F. Boron. Case Western Reserve Univ.
B338 971.5
Na-Driven Cl/HCO3 Exchanger (NDCBE)
Activity Is Essential for Establishing New Steady-State
in Intracellular pH during Metabolic Acidosis in Murine
Hippocampal Neurons and Astrocytes. A. Salameh, W.F.
Boron. Case Western Reserve Univ.
B339 971.6
Mouse Slc4a11 Mediates Extracellular-pHSensitive H+-Conduction in Xenopus Oocytes. E.J. Myers, A.
Marshall, M.D. Parker. Univ. at Buffalo and SUNY Eye Inst.
B340 971.7
Acidic Eye Drops De-swell the Edematous
Corneas of Slc4a11-null Mice: Evidence for Functional
Coupling between Slc4a11 and the H+/Lactate Cotransporter
Mc. t1 E. Myers, S.P. Patel, A. Marshall, M.L. Jennings, M.D.
Parker. Univ. at Buffalo, SUNY Eye Inst., VA Western NY Hlth.
Care Syst., Buffalo and Univ. of Arkansas for Med. Sci.
B341 971.8
Dysregulation of Pendrin and NBC-e1 and
Impaired HCO3- Secretion in the Kidneys of CFTR Knockout
Mice: Role in the Pathogenesis of Metabolic Alkalosis in Cystic
Fibrosis M. Varasteh Kia, S.L. Barone, J. Xu, K. Zahedi, M.
Soleimani. Univ. of Cincinnati.
323
M
O
N
PHYSIOLOGYMONDAY
972. PHYSIOLOGY AND PATHOPHYSIOLOGY OF
BARRIERS IN ENDOTHELIA, EPITHELIA, AND
THE BLOOD BRAIN BARRIER
Poster
Exhibit Halls A-D
B342 972.1
Alcohol Consumption Increases Claudin-18
Turnover in Alveolar Epithelial Cells. SC.H. Dorsainvil White,
S.A. Molina, C.T. Capaldo, B.L. Schlingmann, M.H. Koval.
Emory Univ. Sch. of Med.
B343 972.2
Airway Epithelial Monolayer Integrity Is a
Critical Target in COPD. V. Sidhaye, K. Brune, N. Hansel, D.
Robinson. Johns Hopkins Univ.
B344 972.3
The Flavonol Quercetin Improves Endometrial
Barrier Function through the Expression of Tight Junction
Proteins. C. Deachapunya, S. Poonyachoti. Srinakharinwirot
Univ. and Chulalongkorn Univ., Bangkok.
B345 972.4
The Role of a Common HFE Gene Variant in
Brain Iron Accumulation. K.A. Duck, E.B. Neely, I.A. Simpson,
J.R. Connor. Penn State Col. of Med.
973. TRANSPORTERS FOR TRANSMITTERS,
NUTRIENTS, METABOLITES, AND DRUGS
Poster
Exhibit Halls A-D
B346 973.1
A PRIME Labeling Approach for Investigating
Dopamine Transporter Endocytic Trafficking in Dopaminergic
Cell Lines and Neurons. S. Wu, C. Uttamapinant, A. Ting, H.
Melikian. Univ. of Massachusetts Med. Sch. and MIT.
B347 973.2
Structure - Function Relationship of the Human
Mitochondrial Thiamin Pyrophosphate Transporter (MTPPT;
SLC25A19): Critical Roles for Ser34, Lys291 and His137 S.
Sabui, V.S. Subramanian, A. Ghosal, R. Kapadia, H.M. Said.
Univ. of California Irvine, VA Long Beach Healthcare Syst.
B348 973.3
Effect of Chronic Alcohol Exposure on
Physiological and Molecular Aspects of Pancreatic Acinar Cells
Ascorbic Acid Transport. V.S. Subramanian, P. Srinivasan,
H.M. Said. Univ. of California Irvine/VA Med. Ctrs., Long
Beach, CA.
B349 973.4
Functional Analysis of N-Glycosylation in the
Intestinal Peptide Transporter PEPT1 H. Daniel, T. Stelzl.
Techl Univ. of Munich.
324
974. ORAI AND STIM PROTEINS IN
CALCIUM SIGNALLING
Poster
Exhibit Halls A-D
B350 974.1
Hydrogen Sulfide Inhibits Store-Operated
Calcium Entry by Targeting Ora. i3 C. White, J. Kipp, A.
Fresquez. Rosalind Franklin Univ. of Med. and Sci. and
DePaul Univ.
975. TRAFFICKING, MEMBRANE DOMAINS,
POLARITY, AND PROTEIN TARGETING
Poster
Exhibit Halls A-D
B351 975.1
Dysregulation
of
ZnT2-Mediated
Zn
Homeostasis Impairs Epithelial Polarity and Breast
Differentiation. S. Lee, S.L. Kelleher. Penn State Hershey Col.
of Med.
B352 975.2
Regulation of Slack KNa Channel Trafficking by
p38 MAP Kinase. S. Gururaj, A. Bhattacharjee, J. Fleites.
Univ. at Buffalo, SUNY and Pfizer Pharmaceuts., NY.
B353 975.3
The Choroid Plexus Epithelium Displays
Conventional Cell Polarization. J. Praetorius, H.H. Damkier,
I.B. Christensen. Aarhus Univ. and Univ. of Copenhagen.
976. AVIAN OSMOREGULATION: UNIQUE
SOLUTIONS, UNANSWERED QUESTIONS
Poster
Exhibit Halls A-D
B354 976.1
Avian Osmoregulation in Flight: Unique
Metabolic Adaptations Present Novel Challenges. A.R.
Gerson, C. Guglielmo. Univ. of Massachusetts Amherst and
Univ. of Western Ontario.
B355 976.2
Preliminary Examination of a Role for Insulin
in the Regulation of Glucose Excretion in Mourning Doves
(Zenaida macroura) K.L. Sweazea, E.J. Braun. Arizona State
Univ. and Univ. of Arizona.
B356 976.3
The Integration of Gastrointestinal and Renal
Function in Nectar-Feeding Birds. T.J. McWhorter. Sch. of
Animal & Vet. Sci., Univ. of Adelaide.
B357 976.4
Water Balance in Desert Birds – Challenges
in a Rapidly Warming Environment. B.O. Wolf. Univ. of
New Mexico.
B358 976.5
Function of the Ang II System during the
Ontogeny of Archosaurs. D.A. Crossley II, J. Eme, K. Tate,
C. Mueller. Univ. of North Texas, California State Univ. San
Marcos and McMaster Univ., Canada.
MONDAYPHYSIOLOGY
977. COMPARATIVE OSMOTIC, IONIC, AND ACIDBASE REGULATION
979. COMPARATIVE BIOCHEMISTRY
AND ENDOCRINOLOGY
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
B359 977.1
Effects of Varied Ionic Concentrations on the
Feeding Ability of Cordylophora caspia, an Invasive Hydroid.
J.D. Cruise, S.J. Hofer, J.L. Busch, N.C. Folino-Rorem.
Wheaton Col., IL.
B360 977.2
Further Characterization of Anuran-Like
Aquaporins in the Urinary Bladder of Urodeles, Notopthalmus
viridescens and Cynops pyrrhogaster S. Hillyard, Y. Shibata,
R. Ishii, T. Nagai, M. Suzuki. Univ. of Nevada Las Vegas,
NICHD, NIH, Shizuoka Univ. and Keio Univ., Japan.
B361 977.3
Development of a Reporter Assay for
Identifying Osmotically Responsive Enhancers in Euryhaline
Fish. X. Wang, D. Kültz. Univ. of California, Davis.
B362 977.4
Stoichiometry of Novel Protein Modifications
in Livers of Warm-Adapted Threespine Sticklebacks from Baja
California (Mexico) B.B. Levitan, S. Gómez-Jiménez, J. Li,
D. Kültz. Univ. of California, Davis and Ctr. for Food Res. and
Develop. (CIAD), Hermosillo, Mexico.
B363 977.5
Halocline Behavior and Salinity Preference
in the Estuarine Teleost Fish, the Mummichog (Fundulus
heteroclitus) W.S. Marshall, J.C. Tait, E.W. Mercer. St. Francis
Xavier Univ., Antigonish, Canada.
978. COMPARATIVE NUTRITIONAL AND
DIETARY PHYSIOLOGY
Poster
Exhibit Halls A-D
B364 978.1
Chemosensory Prey Preference in Neotropical
Gastropod-Eating Snakes (Dipsadinae: Dipsadini) C.M.
Sheehy III, R.U. Tovar. Univ. of Florida and Univ. of Tulsa.
B365 978.2
Feeding Status and the Rate of Crop Emptying
in the Hissing Cockroach, Gromphadorhina portentosa R.
Medina, H. Contreras. Univ. of La Verne.
B366 978.3
The Effect of Diet on the Metabolic Rate and
Microbiome of Gromphadorhina portentosa H.L. Contreras, T.
Lorenz. Univ. of La Verne.
B367 978.4
Effects of High-Fat Diets on Mortality and
Feeding in the Tobacco Hornworm Caterpillar, Manduca sexta
K.J. Greenlee, L.D. Cambron, G. Thapa, M. Baldwin. North
Dakota State Univ.
B368 978.5
Variation in Size and Progression through
Larval Stages of Drosophila melanogaster Fruit Flies in the
Absence of Dietary Folic Acid. M.B. Powel, S.A. Blatch.
Stevenson Univ.
B369 979.1
Novel Function of Insulin-Like Peptides:
Signaling in Sickness-Induced Anorexia. L.D. Cambron, K.J.
Greenlee. North Dakota State Univ.
B370 979.2
Circulating Concentrations of Progesterone
and Estrogen in Weddell Seals during the Breeding Period
and Early Pregnancy. A.L. Kirkham, M.R. Shero, G.P. Adams,
R. McCorkell, S. Atkinson, J.M. Burns. Univ. of Alaska
Anchorage, Univ. of Alaska Fairbanks, Univ. of Saskatchewan
and Univ. of Calgary, Canada.
B371 979.3
Glucocorticoid Receptor-Mediated Lipolysis
Increases following Chronic Adrenocorticotropin Infusion
in Northern Elephant Seals Pups through Its Imperative
Interaction with Heat Shock 90 Chaperone Protein. P. Juarez,
D. Lee, D. Crocker, J.P. Vasquez-Medina, R. Ortiz. Sch. of
Nat. Sci., Univ. of California Merced and Sonoma State Univ.
B372 979.4
Protein Markers and Mechanisms of Bacterial
Cold Water Disease in Rainbow Trout (Oncorynchus mykiss)
Revealed Using Mass Spectrometry Proteomic Analysis. L.
Root. Univ. of California, Davis.
B373 979.5
Evolution of the Cytochrome c Oxidase Subunit
4 Paralogs. C.D. Moyes, D. Porplycia, J. McDonald. Queen’s
Univ., Canada.
B374 979.6
Tissue-Specific
Seasonal
Changes
in
Mitochondrial Membrane Composition and Respiratory
Function in the Golden-Mantled Ground Squirrel. A.B. Heim,
S.A. Rosales, A.J. Chicco, G.L. Florant. Colorado State Univ.
B375 979.7
The Meadow Jumping Mouse as a Laboratory
Model of Hibernation. W.J. Israelsen, Q. Cong, M.D. Roorbach.
Univ. of Texas Southwestern Med. Ctr.
M
O
N
980. LUNG PHYSIOLOGY: ENDOTHELIAL
CELL BIOLOGY
Poster
Exhibit Halls A-D
B376 980.1
Role of CD36 in ROS-Induced Calcium Influx
in Human Lung Microvascular Endothelial Cells. J. Reyes,
K. Suresh, L. Servinsky, D.B. Pearse, L. Shimoda. Johns
Hopkins Univ. Sch. of Med.
B377 980.2
Hypoxia Stimulates ERK via EGFR Activation
in Human Pulmonary Microvascular Endothelial Cells. H.A.
White, Y. Jin, L.G. Chicoine, B. Chen, L.D. Nelin. Res. Inst. at
Nationwide Children’s Hosp. and The Ohio State Univ.
B378 980.3
Hypoxia-Induced Arginase II Expression
Depends on EGF-Mediated Activation of EGFR. C.M. Pool, Y.
Jin, B. Chen, L.G. Chicoine, Y. Liu, L.D. Nelin. Res. Inst. at
Nationwide Children’s Hosp. and The Ohio State Univ.
B379 980.4
Activation of Adenylyl Cyclase in Pulmonary
Microvascular Endothelial Cells Increases Microparticle
cAMPp Content. S.L. Sayner, L. Hargett, A. Scruggs, R. KC,
T. Yarbrough, N. Bauer. Univ. of South Alabama.
325
PHYSIOLOGYMONDAY
B380 980.5
Lipopolysaccharide and Isoproterenol Alter
Sodium Bicarbonate Cotransporter Phosphorylation in
Pulmonary Microvascular Endothelial Cells. S.L. Sayner. Univ.
of South Alabama.
B381 980.6
The Role of PP5 in the FKBP51 Inhibition of Isoc
Current. C.L. Hamilton, P.I. Kadeba, K.A. Abney, R. Honkanen,
J.G. Scammell, D.L. Cioffi. Univ. of South Alabama.
B382 980.7
Pulmonary Endothelial Heterogeneity in
Response to Infection-Induced Cytotoxic Supernatant. K.A.
Morrow, R. Balczon, D.W. Frank, T.A. Stevens. Univ. of South
Alabama and Med. Col. of Wisconsin.
B383 980.8
cAMP Potentiates Caspase-1 Activation
in Pulmonary Microvascular Endothelial Cells during
Pseudomonas aeruginosa Infection. P. Renema, N.A. Housley,
J.P. Audia, D.F. Alvarez. Univ. of South Alabama.
B384 980.9
Endothelin-Receptor A Mediates Enhanced
Agonist-Induced Intracapillary Neutrophil Retention in Lungs
of Sickle Cell Disease. Z. Zheng, X. Hu, C. Dickerson, S.E.
Meiler, S. Wu. Georgia Regents Univ.
B385 980.10 α1G T-Type Ca2+ Channel Plays a Dual Role
in Control of Pulmonary Microvascular Endothelial Cell
P-Selectin Surface Expression. Z. Zheng, X. Hu, H. Chen, H.
Sellak, M.F. Alexeyev, S. Wu. Georgia Regents Univ. and Univ.
of South Alabama.
B386 980.11 Synergistic Role of Hemin in Endothelial Cell
Activation in the Lungs of Sickle Cell Mice. X. Hu, Z. Zheng,
M.F. Alexeyev, C. Dickerson, S.E. Meiler, S. Wu. Georgia
Regents Univ. and Univ. of South Alabama.
B387 980.12 Hemoglobin Induced Lipid Peroxidation as
an Initiating Factor of Pulmonary Hypertension. D. Irwin, Z.L.
Loomis, K. Redinius, P. Eigenberger, C. Lisk, P. Buehler.
Univ. of Colorado Anschutz Med. Campus, Aurora and USDA,
Rockville, MD.
B388 980.13 ER Stress-BiP Axis Regulates Endothelial
Barrier Dysfunction and Inflammation in Acute Lung Injury.
A. Leonard, A. Rahman, V. Grose, S. Slavin, F. Fazal. Univ.
of Rochester.
B389 980.14 Non-muscle Myosin Light Chain Kinase
Interaction with TRPC1 Mediates Store-Operated Calcium
Entry Independent of STI. M1 M. Tauseef, V. Kini, N. Knezevic,
T.T. Schmidt, R. Amin, W. Li, A. Obukhov, A. Malik, D. Mehta.
Univ. of Illinois at Chicago and Indiana Univ. Sch. of Med.
B390 980.15 Transcriptional Regulation of S1PR1 through
FAK and KLF2 Is Required for Maintaining Endothelial Barrier
Integrity. P. Yazbeck, T. Schmidt, M. Tauseef, D. Mehta. Univ.
of Illinois at Chicago.
B391 980.16 Analysis of the Physical Interaction between
α1G T-Type Calcium Channel and Endothelial Nitric Oxide
Synthase (NOS3) in Pulmonary Microvascular Endothelial
Cells. H. Sellak, H. Chen, M. Alexeyev, S. Wu. Georgia
Regents Univ. and Univ. of South Alabama.
326
981. LUNG PHYSIOLOGY: FLUID BALANCE
Poster
Exhibit Halls A-D
B392 981.1
Reduction in Edema Cuff Size Is Not the
Mechanism of Lung Protection Afforded by Airway Pressure
Release Ventilation. S.V. Jain, M. Kollisch-Singule, S. Roy, G.
Pasquale, T. Sweeney, J. Satalin, P. Andrews, N. Habashi, G.
Nieman, L.A. Gatto. SUNY Upstate Med. Univ., CHU SainteJustine, Montreal, SUNY Cortland and R. Adams Cowley
Shock Trauma Ctr., Baltimore.
B393 981.2
Hypocapnia Aggravates Hypoxia-Induced
Inhibition of Alveolar Na-Transport. H. Mairbaurl, M. Sahinoz,
E. Baloglu. Univ. of Heidelberg, Germany and Acibadem
Univ., Turkey.
982. ENVIRONMENTAL EXPOSURES, OXIDATIVE
STRESS, AND LUNG DISEASE
Poster
Exhibit Halls A-D
B394 982.1
Protective Role of Ergothioneine from Tobacco
Smoke-Induced Oxidative Stress In Vitro and In Vivo. C.
Ehrhardt, M.A. Selo, C.G. Clerkin, B.N. Talbot, J.J. Walsh,
N. Nakamichi, Y. Kato, J.B. Lewis, P.R. Reynolds, S. Nickel.
Sch. of Pharm. and Pharmaceut. Sci., Trinity Col. Dublin, Kufa
Univ., Iraq, Kanazawa Univ., Japan and Brigham Young Univ.
B395 982.2
Mechanisms Involved in the Antioxidant
Properties of Azithromycin in Lung Epithelial Cells Stimulated
with Cigarette Smoke Extract. S. Cuevas, Y. Yang, I.
Armando, P.A. Jose. George Washington Univ. and Univ. of
Texas, Galveston.
B396 982.3
Inter-strain Variation in Mouse Mitochondrial
Genome and Effects of Oxidative Stress. K.C. Verhein, A.
Burkholder, J.L. Nichols, Z. McCaw, J. Marzec, V. Panduri, W.
Gladwell, N. Reeves, J. Malphurs, G. Solomon, T. Wiltshire,
D. Fargo, D. Bell, B. Van Houten, S.R. Kleeberger. NIEHS,
NIH, Research Triangle Park, Eschelman Sch. of Pharm., Univ.
of North Carolina at Chapel Hill and Univ. of Pittsburgh.
B397 982.4
Investigation of the Cardiotonic Steroids,
Marinobufagenin and Resibufogenin, in the Acute Respiratory
Distress Syndrome. M.M.K. Abbas, Q. Chen, A. Das, J. Oliver,
W. Jiang, B. Moorthy, B. Patel, K. Morin, J. Puschett. Texas
A&M Col. of Vet. Med. and Biosci., Texas Children’s Hosp.,
Baylor Col. of Med. and Univ. of Texas-Houston and Mem.Hermann Hosp., Houston.
B398 982.5
Alveolar Acid Injury Causes Endothelial
Mitochondrial Depolarization. R.F. Hough, G.A. Gusarova,
M.N. Islam, J. Bhattacharya. Columbia Univ. Med. Ctr.
B399 982.6
Alterations in the Expression of Profilin1/
pVASP-S157 and Cofilin1/pVASP-S239 in Perinatal
Inflammation/Neonatal Hyperoxia-Induced Lung Injury. M. Ali,
K.M. Heyob, L.K. Rogers. Nationwide Children’s Hosp. and
The Ohio State Univ.
MONDAYPHYSIOLOGY
983. CHEMICAL CONTROL OF AUTONOMIC
NERVOUS SYSTEM FUNCTION IN HEALTH
AND DISEASE
Poster
Exhibit Halls A-D
B400 983.1
The Effect of Obese Levels of Leptin on
Peripheral Chemoreception. R.L. Pye, A. Roy, R.J.A. Wilson,
C.N. Wyatt. Wright State Univ. and Univ. of Calgary, Canada.
B401 983.2
Characterization
of
Ectonucleotidase
Expression in the Rat Carotid Body: Potential Regulation
by Hypoxia? S. Salman, C. Vollmer, C.A. Nurse. McMaster
Univ., Canada.
B402 983.3
Early Postnatal Exposure to Intermittent
Hypoxia Results in Significant Alterations in White Matter
Integrity in a Rat Pup Model of Apnea of Prematurity. R.
Darnall, X. Chen, C. Sirieix, L. Xia, B. Gimi. Dartmouth Geisel
Sch. of Med.
B403 983.4
Chronic Intermittent Hypoxia Suppresses Adult
Neurogenesis and Disrupts Synaptic Plasticity in the Dentate
Gyrus of the Hippocampus through a Pro-oxidant State. C.M.
Pagan, M.A. Khuu, A.Z. Christakis, J-M. Ramirez, A.J. Garcia
III. Seattle Children’s Res. Inst. and Univ. of Washington.
B404 983.5
An Acute Sustained Hypoxic Stress Is Sufficient
to Cause Respiratory Muscle Weakness in the Mouse. A.J.
O’Leary, K.D. O’Halloran. Univiversity Col. Cork, Ireland.
984. CAROTID BODY STRUCTURE AND FUNCTION
Poster
Exhibit Halls A-D
B405 984.1
Activation of a Non-selective Cation Channel
by Store-Operated and Receptor-Mediated Elevation of [Ca2+]
i in Rat Carotid Body Glomus Cells. D. Kim, J. Wang, J.O.
Hogan. Chicago Med. Sch.
B406 984.2
S-Nitrosocysteine Alters Outward Potassium
Current in Isolated Glomus Cells of Rat Carotid Body under
Normoxic and Hypoxic Conditions. P.M. Getsy, G.A. Coffee,
V.E. Sawczak, R.L. Pye, K. Zaman, S.J. Lewis. Case Western
Reserve Univ. and Wright State Univ.
B407 984.3
Developmental Window Exists in the Hypoxic
Ventilatory Response of Juvenile and Adult Male Rats following
Carotid Sinus Nerve Transection. G.A. Coffee, P.M. Getsy,
S.J. Lewis. Case Western Reserve Univ.
B408 984.4
Influence of Blood Flow Velocity on Arterial
Distensibility of Carotid Artery in Healthy Men. J. Sugawara, T.
Tomoto, S. Maeda. AIST and Univ. of Tsukuba.
985. GENE AND PROTEIN RESPONSES AND
FUNCTION IN HYPOXIA
Poster
Exhibit Halls A-D
B409 985.1
Endothelial Cell DNA Integrity following Anoxia/
Reoxygenation Injury. J.L. Barr, R.S. Gibson, M.A. Dubick,
P.D. Bowman. U.S. Army Inst. of Surg. Res., San Antonio.
B410 985.2
Chronic Hypoxia Downregulates Colocalization
of PKG with Its Target BK Channel Proteins in Ovine Cerebral
Arteries. R.B. Thorpe, J.M. Williams, W.J. Pearce. Loma
Linda Univ.
B411 985.3
Activation of the Hypoxia-Inducible Factor
Pathway Induced by PHD2 Deficiency Enhances the Effect of
Running Training in Mice. A. Nunomiya. Tohoku Univ., Japan.
B412 985.4
Prolyl Hydroxylase Domain 2 Deficiency
Promotes Skeletal Muscle Fiber-Type Transition via a
Calcineurin/NFATc1-Dependent Pathway. J. Shin. Tohoku
Univ., Japan.
B413 985.5
Copper Manipulation of the Transcriptional
Activity of Hypoxia-Inducible Factor-1 W. Zhang, Z. Wu, X. Liu,
P. Li, H. Fu, Y.J. Kang. West China Hosp., Sichuan Univ., China.
986. INTERMITTENT HYPOXIA: RESPIRATORY AND
CARDIOVASCULAR CONTROL AND BEYOND
Poster
Exhibit Halls A-D
B420 986.1
Hypoxia Hits below the Diaphragm: Effect
of Acute Hypoxia on the Micturition Reflex. M. Catege, I.C.
Solomon, W.F. Collins. Stony Brook Univ.
B421 986.2
Acute Intermittent Hypoxia-Induced Plasticity:
What About Micturition? W.F. Collins, M. Catege, I.C.
Solomon. Stony Brook Univ.
B422 986.3
Pretreatment with Ampakine CX717 Enhances
Long-Term Facilitation of Inspiratory Hypoglossal (XII)
Bursting, but Only When Initial Burst Output Is Low. S. Turner,
M. Elmallah, A. Hoyt, J. Greer, D. Fuller. Univ. of Florida and
Univ. of Alberta.
B423 986.4
Antioxidant and Angiotensin AT1 Receptor
Antagonist Treatment Reduced the Hypertension Induced
by Chronic Intermittent Hypoxia in Rats, but Had Different
Effects on Endothelial Dysfunction. R. Iturriaga, B. Krause,
P. Casanello, A.C.R. Dias, P. Arias, R. Del Rio. Pontifical
Catholic Univ. of Chile.
B424 986.5
Chronic Intermittent Hypoxia Altered Stability of
Rhythm Generation but Increased Robustness of Respiratory
Network. T. Dashevskiy, A.J. Garcia III, J-M. Ramirez. Seattle
Children’s Res. Inst. and Univ. of Washington.
B425 986.6
Role of PTEN in Hypoxic Pulmonary
Vasoconstriction. A. Krauszman, T. Mak, D. Sheppard, K.
Szaszi, W. Kuebler.
St. Michael’s Hosp.,Toronto, Charité, Med. Univ. Berlin, Univ.
Hlth. Network, Toronto, UCSF and Univ. of Toronto.
327
M
O
N
PHYSIOLOGYMONDAY
B426 986.7
and Medicine I: Structural Frame of Life Control. X-G. Sun.
Fuwai Hosp., Chinese Acad. of Med. Sci., Beijing.
987. CONTROL OF BREATHING:
RHYTHM GENERATION
Poster
988. CONTROL OF BREATHING:
CONNECTIVITY, NEUROMODULATION
AND NEUROTRANSMISSION
Exhibit Halls A-D
Poster
Exhibit Halls A-D
B427 987.1
Inhibitory Control of Active Expiration by
the Kölliker-Fuse in Rats. S.E.M. Jenkin, W.K. Milsom,
D.B. Zoccal. Univ. of British Columbia and São Paulo State
Univ., Araraquara.
B428 987.2
Role of GABA and Glycine in the Development
of Respiratory Rhythmogenesis in the Embryonic Zebra Finch.
P.S. Stein, K.L. Pickett, M.A. Vincen-Brown, J.Q. Pilarski.
Idaho State Univ.
B429 987.3
Functional
Identification
of
Distinct
Subpopulations of PreB&ötzinger Complex Neurons Regulating
Separate Respiratory Motor Outputs. G. Montandon, R.
Horner. Univ. of Toronto.
B430 987.4
Disturbances in Central Respiratory Rhythm
Generation May Contribute to Breathing Disturbances in
Prematurely Born Mice. S.C. Ramirez, J.E. Koschnitzky, N.A.
Baertsch, T.M. Anderson, C.V. Smith, J-M. Ramirez. Seattle
B431 987.5
The Role of Dbx1-Derived Cells in the
Generation of Inspiration In Vivo. N.A. Baertsch, J.M. Ramirez.
Seattle Children’s Res. Inst.
B432 987.6
To Sigh or Not to Sigh: Role of Glia in Sigh
Generation. T. Dashevskiy, J. Bloom, J-M. Ramirez. Seattle
B433 987.7
KCNQ Potassium Channels Reverse Opioid
Suppression of Respiratory Drive in preBötzinger Dbx1+
Inspiratory Neurons by a Presynaptic Mechanism. A.D. Wei,
J-M. Ramirez. Seattle Children’s Res. Inst. and Univ. of
Washington Sch. of Med.
B434 987.8
Postinspiratory Complex: A Third Excitatory
Respiratory Oscillator. T.M. Anderson, A.J. Garcia III, J.C.
Bloom, N.A. Baertsch, J. Pollak, J-M. Ramirez.
Univ. of Washington and Seattle Children’s Res. Inst.
B435 987.9
Hypercapnic
Acidosis
Acts
on
Two
Opposing Mechanisms to Modulate the Efficacy of Opioid
Neuromodulation of Inspiratory Drive. A.J. Garcia, T.M.
Andreson, J-M. Ramirez. Seattle Children’s Res. Inst. and
Univ. of Washington.
B436 987.10 Unbuckling the Buccal Oscillator in the
American Bullfrog. M.I. Baghdadwala, W.M. Trask, R.J.A.
Wilson. Hotchkiss Brain Inst., Calgary,Canada.
B437 987.11 Becoming a Couple: The Developing
Relationship between Respiratory Oscillators of the American
Bullfrog. W.M. Trask, M.I. Baghdadwala, R.J.A. Wilson.
Hotchkiss Brain Inst., Calgary, Canada.
B438 987.12 Exploring
Degeneracy
of
Brainstem
Networks That Generate the Respiratory Rhythm. S. Jones,
M. Dutschmann. Florey Inst. of Neurosci. and Ment.
Hlth., Melbourne.
328
B439 987.13 New Theory of Holistic Integrative Physiology
and Medicine III: How We Generate Rhythm and Frequency of
Breathing. X-G. Sun. Cardiovasc. Fuwai Hosp., Chinese Acad.
of Med. Sci., Beijing.
B440 988.1
ATP Excitation of the preBötzinger Complex
and Inspiratory Neurons In Vitro Is Mediated in Part via a PLC/
IP3-Mediated Increase in [Ca2+]i Y. Zhang, A. Gourine, S.
Kasparov, T. Alvares, G. Funk. Univ. of Alberta, University Col.
London and Univ. of Bristol.
B441 988.2
The Background Sodium Channel NALCN
Regulates Basal Excitability of Chemosensitive Retrotrapezoid
Nucleus Neurons and Stimulation of Breathing by CO2 Y. Shi,
C. Abe, B. Holloway, S. Shu, N. Kumar, J. Weaver, J. Sen,
E. Perez-Reyes, R. Stornetta, P. Guyenet, D. Bayliss. Univ.
of Virginia.
B442 988.3
Acetylcholine
Combined
with
Acetylcholinesterase Blockade within the Commissural
Nucleus of the Solitary Tract Increases Respiratory Activity. W.I.
Furuya, M. Bassi, E. Colombari, J.V. Menani, D.B. Zoccal,
D.S. Colombari. São Paulo State Univ., Araraquara.
B443 988.4
Noradrenergic Signaling in the Retrotrapezoid
Nucleus Differentially Modulates Breathing in Anesthetized Rats
by Alpha-1 and Alpha-2 Receptor-Dependent Mechanisms.
L.M. Oliveira, D.K. Mulkey, T. Moreira, A.C. Takakura. Univ. of
São Paulo and Univ. of Connecticut.
B444 988.5
Mapping Projections of Excitatory and
Inhibitory preBötzinger Complex Neurons. C.F. Yang, J.L.
Feldman. UCLA.
B445 988.6
Characteristics of Breathing Rate Control
by Neurons in the Pontine Medial Parabrachial Region. E.J.
Zuperku, A.G. Stucke, F.A. Hopp, E.A. Stuth. Clement J.
Zablocki DVA Med. Ctr., Med. Col. of Wisconsin and Children’s
Hosp. of Wisconsin, Milwaukee.
B446 988.7
The Pontine Respiratory Group Partially
Mediates Clinical Opioid-Induced Respiratory Depression in
Young Rabbits. J.R. Miller, E. Stuth, F. Hopp, E. Zuperku, A.
Stucke. Carthage Col. and Med. Col. of Wisconsin.
B447 988.8
Airway Deflation-Activated Receptors Are
Stimulated by Hypertonic Saline. J. Guardiola, M. Proctor, J.
Yu. Louisville VA Med. Ctr. and Univ. of Louisville.
B448 988.9
Cardiorespiratory Coupling Is Dependent on a
Conditionally Expressed Inspiratory Antecedent in the In Situ
Rodent Preparation. D.M. Baekey. Univ. of Florida.
B449 988.10 Acute Lung Injury Alters AMPA Receptor
Subunit Density in the Dorsal Vagal Complex. D.G. Litvin, T.E.
Dick, F.J. Jacono. Case Western Reserve Univ.
MONDAYPHYSIOLOGY
989. ASTROCYTE AND
NEUROGLIAL INTERACTIONS
Poster
Exhibit Halls A-D
B450 989.1
Insulin-Like Growth Factor I Regulates
Astrocyte Function. N.M. Ashpole, S. Tarantini, Z. Ungvari, W.
Sonntag. Univ. of Oklahoma Hlth. Sci. Ctr.
B451 989.2
MCT Expression in the Ventromedial
Hypothalamus Is Not Increased by Recurrent Hypoglycemia.
D.J. Oberlin, M. Fecych, C. Murray, R. Morrison, L. Wideman,
L. Beverly. Univ. of North Carolina at Greensboro.
B452 989.3
Neurovascular Coupling Is Coordinated by
the Activation of Nitric Oxide Production in Astrocytes. M.D.
Puebla, M.F. Muñoz, X. Figueroa. Pontifical Catholic Univ. of
Chile, Santiago.
990. BLOOD-BRAIN BARRIER, BRAIN BLOOD FLOW
AND METABOLISM
Poster
Exhibit Halls A-D
B453 990.1
Improvement in Cerebral Autoregulation during
Recovery Phase following Concussion Is Associated with
Reduced Postural Sway: A Pilot Study. K. Maffuid, L. Ryan,
M.N. Murphy, P.F. Davis, S. Purkayastha. So. Methodist Univ.
B454 990.2
The Use of Intransally-Delivered Elastin-Like
Polypeptide for Drug Delivery to the Central Nervous System.
J.W.D. McGowan, P.J.S. Vig, G.L. Bidwell. Univ. of Mississippi
Med. Ctr.
B455 990.3
Alterations in Doublecortin Expression in
Human Neuronal Stem Cells in Response to Angiotensinergic
Stimulation in Proliferation and Differentiation Conditions. B.
Blanco, L.E. Couling, N. Siddiqi, J.R. Munoz, R.C. Speth.
PIne Crest Sch., Fort Lauderdale and Nova Southeastern
Univ., Fort Lauderdale and Davie, FL.
991.NEUROENDOCRINOLOGY/
NEUROIMMUNOLOGY
Poster
Exhibit Halls A-D
B456 991.1
Chronic Binge Alcohol Exacerbates Apoptotic
Signaling in Simian Immunodeficiency Virus-Infected
Macaques. J.K. Maxi, G.J. Bagby, S. Nelson, P.J. Winsauer,
P.E. Molina. LSU Hlth. Sci. Ctr., New Orleans.
B457 991.2
Neonatal Maternal Separation Increases
Microglial Activation in Brainstem Regions Controlling the
Laryngeal Chemoreflex. C. Baldy, S. Boisjoly-Villeneuve,
S. Fournier, M-E. Tremblay, R. Kinkead. CHU de Québec,
Laval Univ.
B458 991.3
GABAB Receptor Plasticity in Corticotrophin
Releasing Hormone Neurons in the Paraventricular Nucleus
during Chronic Unpredictable Stress. Y. Gao, J-J. Zhou, D-P.
Li. MD Anderson Cancer Ctr.
B459 991.4
Androgenic Regulation of Sex Differences in
Cortical Thickness of the Developing Mouse Brain. D. Miyasaki,
L. Ramos, H-W. Tsai. California State Univ., Long Beach.
B460 991.5
Sex-Specific
Effect
of Androgen
on
SFSWAP Expression in the Developing Mouse Cortex and
Hippocampus. A. Ridder, Y.Y. Lee, H-W. Tsai. California State
Univ. Long Beach.
B461 991.6
Effects of Water-Immersion Restraint Stress
on Some Biochemical Parameters in Wistar Rats and Roles
of Selenium and Vitamin E. Y. Sadau, A.B. Adelaiye, R.A.
Magaji, J.O. Ayo, A.I. Isa. Col. of Med. Sci., Gombe State Univ.
and Ahmadu Bello Univ., Nigeria.
B462 991.7
Chronic
Inflammatory
Demyelinating
Polyneuropathy: Muscle Atrophy Associated with Denervation
and Neuromuscular Transmission Instability. K.J. Gilmore,
K. Kimpinski, D. Stashuk, T.J. Doherty, C.L. Rice. Univ. of
Western Ontario, Univ. of Waterloo and Schulich Sch. of Med.
& Dent., Canada.
B463 991.8
Depletion of Brain Perivascular Macrophages
Mitigates Depressive-Like Behavioral Consequences of
Chronic Mild Stress. J-S. Grigoleit, E. Alvarez, C.B. Farrokhi,
P.E. Sawchenko. Salk Inst. for Biol. Studies.
B464 991.9
Acute Stress Diminishes M-Current in
Corticotrophin-Releasing Hormone Neurons through AMPK
Activation. D.P. Li, J-J. Zhou, Y. Gao. Univ. of Texas MD
Anderson Cancer Ctr.
992. NEUROEXCITABILITY, NEUROTRANSMISSION
AND NEUROPLASTICITY
Poster
Exhibit Halls A-D
B465 992.1
Differential Responses of Male and Female
Microglia to LPS and Estrogen May Contribute to Sexually
Dimorphic Effects of Inflammation on Phrenic Long-Term
Facilitation. A.N. Gardner, B.J. Dougherty, J.J. Watters. Univ.
B466 992.2
Increased
Probability
of
Release
in
Huntington’s Disease Neuromuscular Junctions. A. Khedraki,
E.J. Reed, M.M. Rich, A.A. Voss. Wright State Univ.
B467 992.3
Reduced Glutamate Channel Phosphorylation
in Pain-Related Brain Areas in a Transgenic Model of Sickle
Cell Disease. B.V. Towne, D.M. LeBlanc, J.A. Paul, K.
Gupta, S. Edwards. LSU Hlth. New Orleans and Univ. of
Minnesota, Minneapolis.
B468 992.4
Exploring Neuroplasticity in Acute Mild
Traumatic Brain Injury. X. Arakaki, M. Shoga, D. Till, D.
Strickland, T. Tran, M. Gomez, L. Li, G. Zouridakis, J.
Dawlaty, A. Fonteh, M. Harrington. Huntington Med. Res.
Insts., Pasadena and Univ. of Houston.
B469 992.5
Tolerance to Alcohol-Stimulated Glutamate
Receptor Phosphorylation in the Central Amygdala and
Prefrontal Cortex after Chronic Nicotine Exposure. M.A.
McGinn, C.A. Itoga, R.I. Paulsen, J.E. Reppel, M.A. Farooq,
N.W. Gilpin, S. Edwards. LSU Hlth. Sci. Ctr., New Orleans.
329
M
O
N
PHYSIOLOGYMONDAY
B470 992.6
Kv4.2/4.3 Channels in the Hypothalamic PVN
Contribute to Sympathetic Activation in Angiotensin II-Salt
Hypertension. G.M. Toney, M. Andrade. Univ. of Texas Hlth.
Sci. Ctr. at San Antonio.
B471 992.7
Saporin Inhibits Adonis-Biotin Stimulation of
Proliferation of Cells of Caudate Nucleus of Newborn Lambs.
S. McBride, B.O. Ibe, A. Rajaee, B. Koos. LA BioMed at
Harbor-UCLA Med. Ctr. and UCLA.
B472 992.8
Intraneuronal Acidification with Acetic Acid,
an Ethanol Metabolite, Increases Excitability of Central
Nucleus of Amygdala Neurons with Axon Projecting to Rostral
Ventrolateral Medulla. A.D. Chapp, K.M. Driscoll, Z. Shan,
J.R. Carter, Q-H. Chen. Michigan Technol. Univ.
B473 992.9
Neuronal Specific Caveolin-1 Overexpression
Enhances Dendritic Growth and Arborization in Differentiated
Human Neuronal Stem Cells Derived from Induced Pluripotent
Stem Cells. Z. Zhang, A. Almenar-Queralt, D.M. Roth, H.H.
Patel, B.P. Head. VA San Diego Healthcare Syst. and UCSD.
B474 992.10 Angiotensin Type 1A Receptor Expressing
Neurons in the NTS Receive Direct Solitary Tract Excitatory
Neurotransmission. D.A. Carter, H. Guo, A.M. Allen, S.J.
McDougall. Univ. of Melbourne and Florey Inst. of Neurosci.
and Ment. Hlth., Parkville, Australia.
B475 992.11 Phrenic Long-Term Facilitation Fluctuates
Over the Estrous Cycle and Is Abolished by Ovariectomy in
Young Female Rats. B.J. Dougherty, E.S. Kopp, J.J. Watters.
B476 992.12 Influence of Social Isolation on Serotonergic
Fiber Density in the Auditory Midbrain. R.L. Sandlain, S.M.
Keesom, B.M. Wise, L.M. Hurley. Illinois Inst. of Technol. and
Indiana Univ.
B477 992.13 Maternal High Fat Diet Induces the Expression
of an Inhibitory Glycinergic Current in Rat Dorsal Motor
Nucleus of the Vagus Neurons Regulating Gastric Functions.
C.A. McMenamin, K.N. Browning. Penn State Col. of Med.
B478 992.14 Developmental Regulation of Chloride
Currents in the Dorsal Motor Nucleus of the Vagus of the Rat.
C.A. McMenamin, L. Anselmi, K.N. Browning, R.A. Travagli.
993.NEUROINFLAMMATION/NEUROPROTECTION/
ISCHEMIA
Poster
Exhibit Halls A-D
B479 993.1
The Voltage-Gated Potassium Channel Kv1.3
as a Target for Inhibiting Detrimental M1 Microglia Functions.
Y-J. Chen, H.M. Nguyen, I. Maezawa, L-W. Jin, H. Wulff.
Univ. of California, Davis and Univ. of California, Davis Med.
Ctr., Sacramento.
B480 993.2
Reduction of Astrocyte and Microglial
Activation in Insulin/Saline-Treated Diabetic Ketoacidosis by
the KCa3.1 Blocker TRAM-34 N.S. Glaser, C.J. Little, M.D.
Cohen, D.J. Tancredi, H. Wulff, M.E. O’Donnell. Univ. of
California, Sacramento and Davis.
330
B481 993.3
Cytoprotective and Anti-glycation Defenses
in Porcine Brain after Cardiac Arrest and Cardiocerebral
Resuscitation. A.Q. Nguyen, M-G. Ryou, R.A. Hollrah, A.G.
Williams; Jr., G.F. Scott, A.H. Olivencia-Yurvati, R.T. Mallet.
Univ. of North Texas Hlth. Sci. Ctr., Tarleton State Univ. and
Wiley Col., TX.
B482 993.4
Winter-Like Conditions Do Not Enhance
Neuroprotection from OGD in Syrian Hamsters. E.A. Tangog,
I. Pérez, J.S. Hamilton, J.M. Horowitz, B.A. Horwitz. Univ. of
California, Davis.
B483 993.5
Inhibition of Endocannabinoid Degradation
Improves Recovery of Neurobehavioral Function and
Resolution of Neuroinflammation and Synaptic Hyperexcitability
in a Rodent Model of Traumatic Brain Injury. J.P. Mayeux, P.
Katz, S. Edwards, J. Middleton, P. Molina. LSU Hlth. Sci. Ctr.,
New Orleans.
B484 993.6
Association of Impaired Hypoxia-Inducible
Factor-1 Transcriptional Activity with Severer Brain Injury in
Aged Rats in Comparison with Young Rats after Acute Ischemic
Stroke. Y. Guo, X. Li, P. Han, Y. Xiao, P. Zhu, Z. Gou, Y.J. Kang.
West China Hosp., Sichuan Univ.
B485 993.7
Persistent Memory Deficits and Histone
Modification after a Systemic Inflammatory Event. K. Collette,
E. Donzis, N.C. Tronson. Univ. of Michigan and UCLA.
B486 993.8
Inhibition of Sodium Bicarbonate Cotransporter
Exaggerates Ischemic Penumbral Cell Death. H. Yao, P.
Azad, H. Zhao, O. Poulsen, G.G. Haddad. UCSD and Rady
Children’s Hosp.-San Diego.
B487 993.9
Brain Endothelial Cells Segregate LymphaticVenous Biomarkers Into Microparticles following Inflammatory
Cytokine Stimulation. J.W. Yun, A. Minagar, I. Tsunoda, J.S.
Alexander. LSU Hlth. Sci. Ctr., Shreveport.
B488 993.10 The Effect of Keratin on Spinal Cord Injury
Recovery. Z. Zabarsky, A. Marquez-Lara, T.D. Luo, M. Van
Dyke, T.L. Smith. Wake Forest Univ. and Virgina Tech.
B489 993.11 Heparanase Contributes to Sepsis-Associated
Encephalopathy and Neurovascular Glycocalyx Degradation.
J. Ford, J. Orfila, M. Perez, Y. Yang, S. Haeger, P. Herson, E.
Schmidt. Univ. of Colorado, Aurora.
B490 993.12 Pain Related Behaviors in Mice Expressing
Sickle Hemoglobin: Modulation by Bivalent Ligands. C.L.
Rodríguez-Deliz, G. Puig, G. Cataldo, D. Simone. Univ. of
Puerto Rico, Ponce, Univ. of Puerto Rico Sch. of Med. Dent
and Univ. of Minnesota, Minneapolis.
B491 993.13 Translating
TNFR
Signalling
Into
Neuroprotective Strategies: Proof of Concept in Acute In
Vivo Models of Neurodegeneration Using Humanized TNFR
Mice. U.L.M. Eisel, Y. Dong, R. Fischer, P. Naudé, O. Maier,
C. Nyakas, E. van der Zee, E. Guenzi, A. Herrmann, R.
Kontermann, K. Pfizenmaier. Univ. of Groningen, Netherlands,
Univ. of Stuttgart, Germany and Baliopharm AG, Basel.
B492 993.14 Gender Differences in the Association of
Neutrophil Gelatinase-Associated Lipocalin with Cognitive
Impairment and Depression in Heart Failure. R.G.
Schoemaker, L. Gouweleeuw, I.B. Hovens, H. Liu, P.J.W.
Naude, U.M.L. Eisel. Univ. Med. Ctr. Groningen and Univ. of
Groningen, Netherlands.
B493 993.15 Altered Microglia Morphology in the
Hypothalamus after Myocardial Infarction in Mice. R.G.
Schoemaker, L. Gouweleeuw, H. Wajant, O. Maier, U.M.L.
Eisel. Univ. of Groningen, Netherlands, Univ. of Wurzburg and
Univ. of Stuttgart, Germany.
MONDAYPHYSIOLOGY
994. AUTONOMIC ADJUSTMENTS TO
BEHAVIORAL STRESS
996. AUTONOMIC AND
RESPIRATORY INTERACTIONS
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
B494 994.1
Chronic Mild Stress Increases Baseline
Renal Sympathetic Nerve Activity and the Response to Acute
Stressors in Conscious Rats. S. Das, C. Li, H. Chen, N.F.
Rossi. Wayne State Univ. and John D. Dingell VA Med. Ctr.
B495 994.2
Direct Pathway from Ventral Medial Prefrontal
Cortex to Dorsomedial Hypothalamus Drives Psychological
Stress-Induced Hyperthermia. N. Kataoka, K. Nakamura.
Grad. Sch. of Med., Nagoya Univ. and PRESTO, JST,
Kawaguchi, Japan.
B496 994.3
Altered Activity in Efferent Projection Sites of
the Brain Orexin System Is Associated with Poor Cardiovascular
Adaptability in an Animal Model of Hypertension and Attention
Deficit/Hyperactivity Disorder. N. Ahmari, C. Simons, J.
Watkins, M. Long, M. Febo, J. Zubcevic, L. Hayward. Univ.
of Florida.
B497 994.4
Predicting Muscle Sympathetic Nerve Activity
and Mean Arterial Blood Pressure Responses to Mental
Stress. T.R. Wakeham, I.A. Fonkoue, M. Wang, J.R. Carter,
J.J. Durocher. Michigan Technol. Univ.
995. AUTONOMIC ADJUSTMENTS TO EXERCISE
Poster
B503 996.1
Developmental Changes in Breathing Pattern
and Neuronal Morphology in the Respiratory Centers of the
Neonatal Rat. P. Williams, S. Murray, C. Wilson. Loma
Linda Univ.
B504 996.2
Mechanisms Involved in Sodium DepletionInduced Facilitation of Respiratory Responses to Baroreceptor
Activation. P.M. de Paula, K.C. Borsari, D.B. Zoccal, J.V.
Menani. FOAr São Paulo State Univ., Araraquara.
B505 996.3
Changes in the Firing Frequency of Medullary
Respiratory Neurons of Juvenile Female Rats Exposed to
Chronic Intermittent Hypoxia. G.M.P.R. Souza, M.R. Amorim,
D.J.A. Moraes, B.H. Machado. Univ. of São Paulo.
B506 996.4
Possible
Respiratory
Modulation
of
Sympathetic Activity in Rats after Sino-aortic Denervation. M.R.
Amorim, L.G. Bonagamba, G.M. Souza, D.J. Moraes, B.H.
Machado. Sch. of Med. of Ribeirão Preto, Univ. of São Paulo.
B507 996.5
Recruitment of Eosinophils to Lungs and Their
Role in Vagally Mediated Airway Hyperreactivity Depends upon
TNFa and Sensitization Status. S.A. Wicher, D.B. Jacoby, A.D.
Fryer. Oregon Hlth. & Sci. Univ.
997. AUTONOMIC CIRCUITRY IN
THERMOREGULATION OR METABOLISM
Exhibit Halls A-D
Poster
Exhibit Halls A-D
B498 995.1
Central Projections to Medulla for Autonomic
Adjustments to Exercise in Rats. S. Koba, M. Kato, E. Hanai,
T. Watanabe. Tottori Univ. Fac. of Med., Japan.
B499 995.2
Blockade of Acid-Sensing Ion Channels
Attenuates the Skeletal Muscle Metaboreflex in Humans.
I.A. Fernandes, M.O. Campos, D.E. Mansur, J.D. Mattos,
M.P. Rocha, N.G. Rocha, A.C.L. Nóbrega. Fluminense Fed.
Univ., Brazil.
B500 995.3
Role of Endothelial Nitric Oxide in Control of
Peripheral Vascular Conductance during Muscle Metaboreflex
Activation. D. Senador, J. Kaur, A. Alvarez, H.W. Hanna, A.C.
Krishnan, Y.H. Altamimi, D.S. O’Leary. Wayne State Univ.
B501 995.4
Exercise Training Increases Baroreflex
Control of Heart Rate and Decreases Muscle Sympathetic
Nerve Activity in Chronic Chagasic Cardiomyopathy Patients.
A.O. Sarmento, L.M. Antunes-Correa, D.M.L. Lobo, B.E.P.
Carvalho, I.C. Trombetta, M.J.N.N. Alves, M.U.P.B. Rondon,
E. Rondon, M.L.C. Vieira, C. Mady, C.E. Negrao, B.M. Ianni.
Heart Inst., Univ. of São Paulo Med. Sch., Univ. Nove de Julho
(UNINOVE) and Sch. of Phys. Educ. and Sports, Univ. of
São Paulo.
B502 995.5
Centrally Acting Perindopril Attenuates the
Exercise-Induced Increase in Muscle Sympathetic Nerve
Activity during Heavy Dynamic Exercise. G. Moralez, N.P.
Jouett, J. Tian, M.C. Zimmerman, P.B. Raven. Univ. of North
Texas Hlth. Sci. Ctr. and Univ. of Nebraska Med. Ctr.
B508 997.1
Repeated Moderate Heat Exposure Decreases
Resting Sympathetic Activity in Humans. J. Cui, C. Blaha, L.I.
Sinoway. Penn State Hershey Heart and Vasc. Inst.
B509 997.2
Neural Circuit Mechanism for Hypothalamic
Neuropeptide Y-Induced Inhibition of Brown Adipose Tissue
Thermogenesis. Y. Nakamura, Y. Yanagawa, S.F. Morrison,
K. Nakamura. Nagoya Univ. Grad. Sch. of Med. and Gunma
Univ. Grad. Sch. of Med., Japan, Oregon Hlth. & Sci. Univ. and
PRESTO, JST, Japan.
B510 997.3
Decreases in Core Temperature and Sweating
Onset during Whole-Body Heating in Individuals with Multiple
Sclerosis following Administration of 4-Aminopyridine.
M. Huang, D.R. Allen, E.M. Frohman, S.L. Davis. So.
Methodist Univ., Univ. of Texas at Arlington and Univ. of Texas
331
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PHYSIOLOGYMONDAY
998. AUTONOMIC CONTROL AND
AUTOREGULATION OF THE
CEREBRAL CIRCULATION
Poster
Exhibit Halls A-D
B511 998.1
Cerebrovascular Reactivity Is Reduced in
Postmenopausal Women with a History of Hypertensive
Pregnancy Disorders. R.E. Harvey, M.C. Johnson, C.P.
Johnson, M.J. Joyner, V.M. Miller, J.N. Barnes. Mayo Clin.,
Mayo Clin. Col. of Med. and Univ. of Wisconsin-Madison.
B512 998.2
Cerebrovascular Endothelial Function Is
Impaired after Experimental Spinal Cord Injury. M. Jia, A.A.
Phillips, A. Yung, P. Kozlowski, A.V. Krassioukov. Univ. of
British Columbia, Intl. Collab. on Repair Discoveries and GF
Strong Rehab. Ctr.,Vancouver.
999. AUTONOMIC REGULATION OF BODY
FLUID VOLUME
Poster
Exhibit Halls A-D
B513 999.1
Stimulation of Beta Adrenergic Receptor Type3 in the Kidney Triggers Antidiuresis: Physiological Implications
and Possible Therapeutic Target to Treat NDI. G. Procino,
M. Carmosino, S. Milano, M. Dal Monte, G. Schena, M.
Mastrodonato, S. Torretta, A. Gerbino, P. Bagnoli, M. Svelto.
Univ. of Bari, Univ. of Basilicata and Univ. of Pisa.
1000.AUTONOMIC REGULATION OF
NEUROENDOCRINE FUNCTION
Poster
Exhibit Halls A-D
B514 1000.1 3 Hours of Intermittent Hypoxia Increases
Circulating Glucose Levels in Healthy Adults. L.P. Newhouse,
M.J. Joyner, T.B. Curry, J.K. Limberg. Mayo Clin.
1001.DIFFERENCES IN AUTONOMIC REGULATION IN
AGING OR SEX
Poster
Exhibit Halls A-D
B515 1001.1 Greater β-Adrenergic Receptor Mediated
Vasodilation in Women Using Oral Contraceptives. G.L.
Peltonen, J.K. Limberg, R.E. Johansson, J.W. Harrell, J.M.
Kellawan, M.K. Crain, M.W. Eldridge, J.J. Sebranek, B.J.
Walker, W.G. Schrage. Univ. of Wisconsin-Madison.
332
B516 1001.2 Sympathetic Vasoconstriction Is Attenuated
in Young Women during Hypoxia and Cold Pressor Test. A.J.
Ross, M.D. Muller, J.C. Luck, J. Cui, L.I. Sinoway. Hershey
Heart and Vasc. Inst., Penn State Col. of Med.
B517 1001.3 Sex-Dependent Effects of Prenatal Infection
on Adult Cardiovascular Health: Are Females at Greater Risk
for Cardiovascular Disease? L. Hayward, J. Watkins, M. Von
Chamier, L. Reyes, M. Brown. Univ. of Florida and Univ.
B518 1001.4 Evidence for Female-Specific Changes in
the Sympathetic Nervous System in Post-infarction Heart
Failure. M.I. Pinkham, S. Pyner, F.C. Shenton, G. Whalley,
B. Habecker, B. Woodward, S-J.I. Guild, C.J. Barrett. Univ.
of Auckland, Durham Univ. Sch. of Biol. & Biomed. Sci. and
1002.ENTERIC NERVOUS SYSTEM REGULATION
Poster
Exhibit Halls A-D
B519 1002.1 Inhibition of Glial Metabolism Decreases
Intestinal Afferent Nerve Activity. M. Miranda-Morales, F.
Ochoa-Cortes, F.L. Christofi, E.C. Villalobos-Hernandez, C.
Barajas-Lopez. UNAM, Queretaro, Mexico, The Ohio State
Univ. and San Luis Potosi Inst. of Sci. Res. and Technol., Mexico.
1003.INFLAMMATION AND
AUTONOMIC REGULATION
Poster
Exhibit Halls A-D
B520 1003.1 Mapping Multiscalar Variability Dynamics in
1/f Physiologic Phase Space for Tracking the State of Sepsis
Patients. B. Vandendriessche, M. Abas, T.E. Dick, K.A.
Loparo, F.J. Jacono. Case Western Reserve Univ., Univ.
Hosps. Case Med. Ctr. and Louis Stokes DVA, Cleveland.
B521 1003.2 Renal Afferent Neurons Are Altered by
Lipopolysaccharides. K. Rodionova, T. Ditting, S. Loosen,
M. Ziemer, P. Linz, C. Ott, R.E. Schmieder, K. Amann, R.
Veelken. Univ. of Erlangen-Nuremberg.
B522 1003.3 Organophosphorus
Pesticides
Stimulate
Macrophages to Release Factors That Modulate M2
Muscarinic Receptors. B. Proskocil, P. Lein, D. Jacoby, A.
Fryer. Oregon Hlth. & Sci. Univ. and Sch. of Vet. Med., Univ. of
California, Davis.
B523 1003.4 Moderately High Salt Intake Does Not Raise
Blood Pressure but Does Activate Peripheral Immune Cells
with the Capacity to Raise Blood Pressure. J. Zubcevic, N.
Ahmari, D. Diaz, W. Malphurs, C.M. Redlitz, M.A. Andrade,
G.M. Toney. Univ. of Florida and Univ. of Texas at San Antonio.
B524 1003.5 Anti-inflammatory Effect of Brain-Vagal
Stimulation: Implication in Post-operative Gastric Ileus. P-Q.
Yuan, Y. Tache. UCLA David Geffen Sch. of Med. and VA
Greater Los Angeles Healthcare Syst.
MONDAYPHYSIOLOGY
1004.SYMPATHETIC REGULATION IN DIABETES
AND OBESITY
Poster
Exhibit Halls A-D
B525 1004.1 Exaggerated Blood Pressure and Sympathetic
Reactivity in Patients with Type 2 Diabetes. J.R. Vranish, S.W.
Holwerda, D.M. Keller, P.J. Fadel. Univ. of Texas at Arlington
and Univ. of Iowa.
B526 1004.2 Functional Changes of Rostral Ventrolateral
Medulla by Nitric Oxide from iNOS in Conscious Obese Rats.
M.C. Martins-Pinge, F.N.C. Lopes, N.G. Zanluqui, P. PingeFilho. State Univ. of Londrina, Brazil.
B527 1004.3 Enhanced Skeletal Muscle Metaboreflex
Activation in Type 2 Diabetes. M. Mizuno, S.H. Holwerda, J.H.
Mitchell, S.A. Smith, P.J. Fadel. Univ. of Texas Southwestern
Med. Ctr., Univ. of Iowa and Univ. of Texas Arlington.
B528 1004.4 Acute Fructose Overload Induces Baroreflex
Dysfunction in Close Relatives of Type 2 Diabetics. F. Santos,
T. Dipp, B.D.A. Schaan, K.R. Casali, M. Morris, L.U. Signori,
R.D.M. Plentz, M.C. Irigoyen. São Paulo Univ., Porto Alegre,
Sao Jose dos Campos Brazil, Fort Lauderdale and Santa
Maria, Brazil.
B529 1004.5 Treatment of Hypertensive Obese Zucker
Rats with Metformin Enhances Phenylephrine-Induced
Bradycardia and c-Fos Expression in the NTS. P. Chaudhary,
A. Schreihofer. Univ. of North Texas Hlth. Sci. Ctr.
B530 1004.6 The Effect of Stimulation of β2 Adrenergic
Receptor on Glucose Uptake in Skeletal Muscles. H. Gao.
Univ. of South Dakota.
1005.SYMPATHETIC REGULATION IN
HEART FAILURE
Poster
Exhibit Halls A-D
B531 1005.1 Upregulation of Endothelial Nitric Oxide
Synthase and Nitric Oxide in the Kidney Enhances the Blunted
Responses of α1D Adrenoreceptors in the Kidney of Rats with
Left Ventricular Hypertrophy. H.A. Rathore, M.Z. Abdul Sattar,
A. Ahmad, E.J. Johns. Sch. of Pharmaceut. Sci., Univ. Sains
Malaysia and University Col. Cork, Ireland.
B532 1005.2 Endoplasmic Reticulum Stress Induces p44/42
Mitogen-Activated Protein Kinase Signaling, Inflammation and
Renin-Angiotensin System Activity in Forebrain and Contributes
to Sympathetic Nerve Activity in Heart Failure Rats. S-G. Wei,
Y. Yu, R.M. Weiss, R.B. Felder. Univ. of Iowa Carver Col. of
Med. and VA Med. Ctr.
B533 1005.3 Infusion of Losartan Into the 4th Ventricle
Reduced Cardiac Sympathoexcitation in Heart Failure. Y.
Abukar, C.N. May. Florey Inst. of Neurosci. and Ment. Hlth.,
Parkville, Australia.
B534 1005.4 Enhanced Expression of Renal AQP2 and
ENaC in Rats with Chronic Heart Failure: A Role for Renal
Nerves. H. Zheng, J. Fleecs, X. Liu, K.P. Patel. Univ. of
Nebraska Med. Ctr.
B535 1005.5 HCN Channel Blockers Act Pre- and PostSynaptically to Inhibit Synaptic Transmission and Gain in the
Rat Superior Cervical Sympathetic Ganglion. J.P. Horn, P.H.M.
Kullmann. Univ. of Pittsburgh.
B536 1005.6 Regulation of Protein Inhibitor of Neuronal Nitric
Oxide Synthase in the Paraventricular Nucleus during Chronic
Heart Failure: Role for Angiotensin II- AT1R. N.M. Sharma, X.
Liu, H. Zheng, K.P. Patel. Univ. of Nebraska Med. Ctr.
B537 1005.7 Renal Denervation in Male Rats Attenuates
Changes in Cardiac Sympathetic Innervation in Post-infarction
Heart Failure. M.I. Pinkham, M. Loftus, S. Amirapu, C.J.
Barrett. Univ. of Auckland.
1006.SYMPATHETIC REGULATION
IN HYPERTENSION
Poster
Exhibit Halls A-D
B538 1006.1 High Inorganic Phosphate Diet Augments the
Sympathetic Response to Exercise Pressor Reflex Activation
in Rats. M. Mizuno, S. Crawford, C. Carnahan, J.H. Mitchell,
S.A. Smith, W. Vongpatanasin. Univ. of Texas Southwestern
Med. Ctr.
B539 1006.2 Renal Denervation Improves Baroreflex and
GABA System Normalization in Chronic Kidney DiseaseAssociated Hypertension. H-H. Chen, C-J. Tseng. Natl. Yang
Ming Univ. and Kaohsiung Veterans Gen. Hosp., Taiwan.
B540 1006.3 Effect of B-Type Natriuretic Peptide and
Phosphodiesterase 2A Is Coupled to Neurotransmitter Release
in Pro-hypertensive Rats. K. Liu, L. Woodward, D. Ioannides,
C-J. Lu, D. Li, D. Paterson. Univ. of Oxford.
B541 1006.4 The Central Deacetylase Sirtuin1 Decreases
Sympathetic Hyperactivity by Anti-oxidative Stress in
Hypertensive Rats. W. Wang, Z. Wu, C. Ren, Y. Wang. Second
Military Med. Univ., Shanghai.
B542 1006.5 Impaired Cyclic Nucleotide Signalling in Prehypertensive Spontaneously Hypertensive Rats: A Dichotomy
of Pathways? E. Bardsley, D.J. Paterson. Univ. of Oxford.
B543 1006.6 The Connectome of Rostral Ventrolateral
Medulla C1 Neurons. S. Le, B. Dempsey, A. Turner, A. Allen,
A. Goodchild, S. McMullan. Macquarie Univ., Sydney and
Univ. of Melbourne.
B544 1006.7 Dysregulation of Cardiac cAMP in Nicotine
Stimulated Sympathetic Neuronal-Myocyte Co-cultures
from Hypertensive Rats: Are Sympathetic Neurons the
Primary Driver of Autonomic Hypertension? H.E. Larsen, K.
Lefkimmiatis, D.J. Paterson. Univ. of Oxford.
B545 1006.8 Increased
Respiratory-Sympathetic
Coupling via C1 Neurons Contributes to the Development
of Hypertension in the Spontaneously Hypertensive Rat. C.
Menuet, N. Jancovski, J.K. Bassi, A.A. Connelly, A.M. Allen.
Univ. of Melbourne.
B546 1006.9 Are C1 Neurons Involved in the Sympathetic
Overactivity Induced by Chronic Intermittent Hypoxia? D.J.A.
Moraes, L.G.H. Bonagamba, J.F.R. Paton, B.H. Machado.
Sch. of Med. of Ribeirão Preto, Univ. of São Paulo and Sch. of
Physiol. and Pharmacol., Univ. of Bristol.
333
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B547 1006.10 High Fat Diet Induced Hypertension and
Impaired Glucose Tolerance in the Obesity-Prone Sprague
Dawley Rat: Effect of Increased Salt Intake and Renal
Denervation. R. Han, C.T. Banek, N. Asirvatham-Jeyaraj, X.
Wang, J. Osborn. Univ. of Minnesota, Minneapolis.
B548 1006.11 The Role of G Protein-Coupled Estrogen
Receptor in the PVN of Renovascular Hypertensive Rats. N.
Oliveira Maruyama, H. Frank Estrela, T.F. Lucas, C. Segreti
Porto, C. Toledo Bergamaschi, R. Ribeiro de Campos; Jr.
Fed. Univ. of São Paulo.
B549 1006.12 Roles of Central α2 and AT1 Signal Transduction
via Gαi2 Proteins in Blood Pressure Regulation in Response to
an Acute Sodium Challenge. J.W. Shim, R.D. Wainford, C.Y.
Carmichael. Boston Univ.
B550 1006.13 Effect of Renal Denervation and Celiac
Ganglionectomy on Mean Arterial Pressure in the
Hypertensive Schlager (BPH/2J) Mice. M.M. Gauthier, C.
Breitenstein, N. Asirvatham-Jeyaraj, J.W. Osborn. Univ. of
B551 1006.14 Role of Renal Nerves in Cardiovascular Nuclei
and Kidneys in Renovascular Hypertensive Rats. E.E. Nishi,
G.N. Gomes, J.C. Perry, A.Y. Simões, C.T. Bergamaschi,
R.R. Campos. Fed. Univ. of São Paulo.
1007.ALTITUDE AND HYPOXIA
Poster
Exhibit Halls A-D
B552 1007.1 PETCO2 in Women at Sea-Level and upon Acute
Exposure to Normobaric Hypoxic Environments Simulating
3,500 m. K. Kambis, M. Yasukawa, T. Moran, A. Pleasant, G.
Hafner, V. Barbour, C. Duckworth, S. Muza, R. Looft-Wilson.
Col. of William & Mary, Chuo Univ., Tokyo and U.S. Army Res.
Inst. of Envrn. Med., Natick, MA.
B553 1007.2 Handgrip Training with Chronic Concomitant
Exposure to Moderate Altitude Improves Blood Pressure
Responses and Delays the Onset of Fatigue. S.S. Jarvis. No.
Arizona Univ.
B554 1007.3 Aerosolized
Perfluorochemical
Rescue
against Acute Altitude-Induced Pulmonary Compromise. M.R.
Wolfson, J. Wu, S.T. Baker, C. Gill, J. Johnson, L. Poole, T.H.
Shaffer. Katz Sch. of Med. at Temple Univ.
B555 1007.4 Maximum Blood Lactate Responses Acutely
and after Two Weeks of Moderate Altitude Exposure in a Large
Multi-year Study J. Davis. Alma Col., MI.
B556 1007.5 Three Hours of Intermittent Hypoxia in Young
Healthy Humans Induces Electrocardiographic Changes. S.E.
Baker, L.P. Newhouse, M.J. Joyner, T.B. Curry, J.K. Limberg.
Mayo Clin.
B557 1007.6 The Number of Nitrogen Breathing Epochs
Influences the Heart Rate and Blood Pressure Response
to Hypoxia. J.R. Sackett, S. Sarker, G.L. Coleman, C.L.
Chapman, Z.J. Schlader, B.D. Johnson. Univ. at Buffalo.
B558 1007.7 VO2max Is Restored after Prolonged Exposure
to Moderate Altitude. K. Heinicke, I. Heinicke, W. Jelkmann,
P. Rawlings, C. Behn, M. Gassmann. Univ. of Bayreuth,
Germany, Univ. of Zurich, Univ. of Luebeck, Germany, Fac. of
Med., Univ. of Chile, Intl. Ctr. for Andean Studies, Santiago and
Univ. Peruana Cayetano Heredia, Peru.
334
B559 1007.8 Highland Andean Populations Show Reduced
Variation in the Hypoxic Ventilatory Response. E.C. Heinrich,
E. Gaio, F.L. Powell, J.L. Macarlupú, C. Anza-Ramirez,
N. Corante, G. Vizcardo-Galindo, F.C. Villafuerte, T.S.
Simonson. UCSD, Univ. of Brasília and Univ. Peruana
Cayetano Heredia, Peru.
B560 1007.9 Therapeutic Role of Ambrisentan for the
Treatment of Hypoxic Pulmonary Vasoconstriction: Impact of
Intrapulmonary Delivery. S. Ferguson, Z. Loomis, J. Harral, K.
Redinius, K. Dixon, M. Anderson, D. Irwin. Univ. of Colorado
Denver, Aurora.
1008.METABOLISM AND ENEREGETICS OF MUSCLE
AND RELATED TISSUES
Poster
Exhibit Halls A-D
B561 1008.1 mdx Mice Are Protected from Diet-Induced
Obesity Possibly Due to Increased Skeletal Muscle Energy
Expenditure. F. Kwon, D. Gamu, A.R. Tupling. Univ. of
Waterloo, Canada.
B562 1008.2 Phospholamban Is a Potential Regulator of
Skeletal Muscle and Whole-Body Metabolism. D. Gamu, S.
Mazereeuw, A.R. Tupling. Univ. of Waterloo, Canada.
B563 1008.3 Novel Insight Regarding the Trajectory and
Time-Course of Immobilisation-Induced Impairment of Limb
Glucose Uptake in Healthy Volunteers. A. Burns, A. Nixon,
F. Stephens, S. Francis, P. Gowland, P. Greenhaff. Univ.
of Nottingham.
B564 1008.4 Dysregulation of the Energy-Sensing AMPK
Pathway in Skeletal Muscle-Specific ERRα-/- Mice. J. Huss,
M. McDonald, A. Hamilton. City of Hope, Duarte, CA.
B565 1008.5 IL-15 Promotes Mitochondrial Activity through
an ERK1/2-PPAR&Δ Signaling Axis in C2C12 Skeletal Muscle
Cells. M.J. Abbott, J.E. Krolopp, T. Nakamoto. Schmid Col. of
Sci. and Technol., Chapman Univ.
B566 1008.6 Enhanced Gastrocnemii Aerobmic Metabolism
in Aged Male Rats following Postnatal Hyperoxia. L.H. Tetri,
R.K. Braun, K. Haraldsdottir, D.F. Pegelow, K.N. Gross, M.W.
Eldridge. Univ. of Wisconsin-Madison.
B567 1008.7 Regulation of Metabolism by Estrogen
Receptor Alpha. A.E. Archer, R.S. Rogers, J.L. Wheatley,
K. White, M.A.K. Rumi, M.J. Soares, P.C. Geiger. Univ. of
Kansas Med. Ctr.
B568 1008.8 Beta-Aminoisobutyrate,
a
Circulating
Metabolite Which Regulates Beta-Cell Insulin Secretory
Function. T.P. Solomon, M. Gillum. Univ. of Birmingham, U.K.
and Univ. of Copenhagen.
MONDAYPHYSIOLOGY
1009.MUSCLE ATROPHY AND HYPERTROPHY
Poster
Exhibit Halls A-D
B569 1009.1 Massage Induces an Increase in DNA
Synthesis and Satellite Cell Number in Rat Muscle Recovering
from Atrophy. A.M. Hayek, A.L. Confides, S.M. Abshire,
B. Miller, K. Hamilton, K.A. Baeverstad, F. Peelor, T.A.
Butterfield, E.E. Dupont-Versteegden. Univ. of Kentucky and
Colorado State Univ.
B570 1009.2 Low-Frequency Electrical Stimulation (AcuLFES) Attenuates Denervation-Induced Muscle Atrophy by
Increasing Muscle Regeneration. X.H. Wang, J.D. Klein, H.
Wang. Emory Univ.
B571 1009.3 REDD1 Alters the Rate of Muscle Hypertrophy
following Functional Overload. B.S. Gordon, G. Nader, J.L.
Steiner, L.S. Jefferson, S.R. Kimball. Univ. of Central Florida,
Penn State and Penn State Col. of Med.
B572 1009.4 The Role of Denervation in Cytokine-Mediated
Muscle Dysfunction in Muscles of Old Mice. C.A. Staunton,
N. Pollock, A. Lightfoot, A. Vasilaki, R. Barrett-Jolley, A.
McArdle, M. Jackson. Univ. of Liverpool.
B573 1009.5 Mechanically Overloaded Plantaris Muscles
Display Ectopic Sarcolipin Expression That Is Required for
Myofiber Hypertrophy and Remodelling. V.A. Fajardo, B.A.
Rietze, P.J. Chambers, J. Quadrilatero, A.R. Tupling. Univ. of
Waterloo, Canada.
B574 1009.6 Sarcolipin Is Upregulated in Response
to Soleus Unloading Caused by Tenotomy and Opposes
Muscle Atrophy. V.A. Fajardo, B.A. Rietze, P.J. Chambers, J.
Quadrilatero, A.R. Tupling. Univ. of Waterloo, Canada.
B575 1009.7 Repeated Bouts of Resistance Training with
Short Interval Activate Akt-mTOR Signaling, but Not Protein
Synthesis in Mouse Skeletal Muscle. J. Takegaki, Y. Arihara,
R. Ogasawara, A. Tsutaki, K. Nakazato, N. Ishii. Univ. of
Tokyo, Nagoya Inst. of Technol. and Nippon Sport Sci. Univ.
B576 1009.8 TRB3 Regulates Denervation-Induced Muscle
Atrophy and Insulin Resistance in Mouse Skeletal Muscle.
R.H. Choi, H-W. Jeong, A. McConahay, M.F. Hirshman,
L.J. Goodyear, H-J. Koh. Univ. of South Carolina and Joslin
Diabetes Ctr.. Boston.
B577 1009.9 Mouse Cachectic Skeletal Muscle mTORC1
Signaling in Response to Acute Eccentric Contractions. J.P.
Hardee, S. Gao, B.N. VanderVeen, D.K. Fix, K.L. Hetzler, J.A.
Carson. Univ. of South Carolina.
B578 1009.10 Maternal Protein Intake as a Determinant of
the Total Number of Motor Units and Muscle Fibres in Mice. A.
Vasilaki, I. Giakoumaki, N. Pollock, K. Goljanek-Whysall, A.
McArdle, A.A. Sayer. Univ. of Liverpool and Newcastle Univ.
B579 1009.11 The Sirtuin SIRT6 Represses Expression of
Cachexia-Associated Cytokine Myostatin by Blocking Its NFκB-Dependent Gene Transcription. M. Gupta, S. Samant, R.
Bao, V. Pillai. Univ. of Chiacgo.
B580 1009.12 Transcriptional Regulation of Skeletal Muscle
Atrophy-Induced Gene Expression by Muscle-Specific Ring
Finger 1 K. Kakareka, D. Waddell. Univ. of North Florida.
B581 1009.13 Effect of Nox2 Inhibition Unloading-Induced
Changes in Morphology and nNOSµ Translocation in the Rat
Soleus. J.M. Lawler, J.M. Hord, D.A. Rodriquez, Y. Lee, V.
Guzzoni, E.E. Garcia-Villatoro, M. Garcia, J.M. Kuczmarski,
M.S. Lawler. Texas A&M Univ., Fed. Univ. of São Carlos, Brazil,
Penn State Col. of Med. and Georgia Tech.
B582 1009.14 Identification and Characterization of Allograft
Inflammatory Factor 1-Like in Skeletal Muscle. K. Tran, D.
Waddell. Univ. of North Florida.
B583 1009.15 K (Lysine) Acetyltransferase 6B Is Upregulated
during Neurogenic Skeletal Muscle Atrophy and Is Differentially
Expressed in MuRF1-Null Mice. R. West, D. Waddell. Univ. of
North Florida.
B584 1009.16 FGGY
Carbohydrate
Kinase
Domain
Containing Is Upregulated during Neurogenic Skeletal Muscle
Atrophy. B. De Las Casas, D. Waddell. Univ. of North Florida.
B585 1009.17 Basal and Stretch-Induced Myotube Protein
Synthesis Regulation by gp130 Signaling. S. Gao, J.A. Carson.
1010.MUSCLE PLASTICITY AND
GENE REGULATION/EXPRESSION
Poster
Exhibit Halls A-D
B586 1010.1 Chronology of Early Heat Stress Mediated
Changes in Oxidative Skeletal Muscle. O. Volodina, S.
Ganesan, S. Pearce, N. Gabler, L. Baumgard, R. Rhoads, J.
Selsby. Iowa State Univ. and VPI and State Univ.
B587 1010.2 Acute Expression of PGC-1α Isoforms
in Skeletal Muscle of Postmenopausal Women following
Resistance Exercise. J.L. Kiwata, C. Tuzon, J.C. Rice, E.T.
Schroeder, C.M. Dieli-Conwright. Univ. of So. California.
B588 1010.3 Transcriptome Analysis Reveals Regulation of
Novel lncRNAs Transcribed Near Contractile Protein-Coding
Genes during Skeletal Muscle Unloading. J.D. Resnick,
A.J. Lowrey, R.G. Akers, L.A. Theodore, A.M. Wiles, C.E.
Pandorf. Mercer Univ.
B589 1010.4 Regulation of Skeletal Muscle Protein
Translation during Energetic Stress. C.A. Wolff, F.F. Peelor
III, E.B. Petrilli, R.M. Casey, J.T. Allison, K.L. Hamilton, B.F.
Miller. Colorado State Univ.
B590 1010.5 Long-Term Quercetin Treatment Is Unable
to Sustain Elevated PGC-1α Pathway Activity in the mdx
Diaphragm. H. Spaulding, C. Ballmann, J. Quindry, J. Selsby.
Iowa State Univ. and Auburn Univ.
B591 1010.6 Expression of the Dystrophin-Associated
Protein Complex in the Absence of Skeletal Muscle AMPK.
A.G. Dial, J.S. Lally, A.L. Bujak, G.R. Steinberg, V. Ljubicic.
B592 1010.7 The Correlation between Tfeb and PGC-1α in
Skeletal Muscle. A.T. Erlich, A. Vainshtein, D. Hood. Sch. of
Kinesiol. and Hlth. Sci., York Univ., Canada.
B593 1010.8 The Aging Muscle Milieu and Transcription
of PGC-1α: A Role for Contractile Activity? H.N. Carter, M.
Shuen, K. Gavendo, D.A. Hood. York Univ. and Muscle Hlth.
Res. Ctr., Toronto.
335
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PHYSIOLOGYMONDAY
B594 1010.9 Glial Cell Line-Derived Neurotrophic Factor
Protein Secretion by Skeletal Muscles Is Altered by Activity of
L-Type Calcium Channels. A.M. Boynton, J.M. Spitsbergen.
Western Michigan Univ.
B595 1010.10 Deficits in Excitation-Contraction Coupling in
Aged Mice. H. Li, D.A.G. Mázala, E.R. Chin. Univ. of Maryland
College Park.
1011.CARDIAC MUSCLE
Poster
Exhibit Halls A-D
B596 1011.1 The Use of an Adenine Diet to Induce Uremic
Cardiac Hypertrophy in Mice. E.M. Adamic, A. Von Schulze,
C. Amat-Fernandez, H. Lee, D. Daniel, M.J. Wacker, C.D.
Touchberry. Sch. of Hlth. Sci., Univ. of Memphis and Sch. of
Med., Univ. of Missouri- Kansas City.
B597 1011.2 Organ Perfusion during Voluntary Pulmonary
Hyperinflation: A Magnetic Resonance Imaging Study. K. Kyhl,
I. Drvis, O. Barak, T. Mijacika, N.H. Secher, Z. Dujic, A. Buca,
P.L. Madsen. Rigshosp., Copenhagen, Univ. of Zagreb Sch.
of Kinesiol., Croatia, Univ. of Split Sch. of Med., Denmark,
Univ. of Copenhagen, Clin. Hosp. Ctr., Split and Herlev
Hosp., Copenhagen.
B598 1011.3 Downregulation of Myocardial Pigment
Epithelium-Derived Factor in Mice Exposed to Cigarette Smoke:
A Possible Mechanism for Smoking-Related Cardiovascular
Disease. J. McHowat, H. Kuenzel, S. Kispert, J. Marentette,
G. Kolar. Saint Louis Univ.
B599 1011.4 Renin Overexpression Leads to Increased
Titin-Based Stiffness Contributing to Diastolic Dysfunction in
Hypertensive mRen2 Rats. T. Csipo, A. Kovacs, G.A. Fulop,
A. Kovacs, B. Bodi, B. Juhasz, D. Priksz, H. Granzier, I.
Edes, Z. Papp, J. Barta, A. Toth. Univ. of Debrecen Fac. of
Med., Hungary and Univ. of Arizona.
B600 1011.5 Striatin Expression Is Altered during Cardiac
Remodeling and It Regulates Cardiomyocyte Response to
Adrenergic Stimuli. S. Alotaibi, E. Alsolme, R. Alsomali, P.
Kvietys, N. Dzimiri, M. Nader. Alfaisal Univ. Med. Sch. and
King Faisal Spec. Hosp. and Res. Ctr., Saudi Arabia.
B601 1011.6 Regional Gradients in Tissue Anisotropy during
Pressure Overload Hypertrophy in the Rat Left Ventricle. E.D.
Carruth, A.D. McCulloch, J.H. Omens. UCSD.
336
1012.CONTRACTILE AND REGULATORY PROTEINS
Poster
Exhibit Halls A-D
B602 1012.1 Regulation of Actin Dynamics by WNT-5A:
Implications for Human Airway Smooth Muscle Contraction. T.
Koopmans, K. Kumawat, M. Menzen, A. Halayko, R. Gosens.
Univ. of Groningen and Univ. of Manitoba.
B603 1012.2 Phosphorylation and Calcium Antagonistically
Tune Myosin-Binding Protein C’s Molecular Structure and
Function. M.J. Previs, J.Y. Mun, A.J. Michalek, S.B. Previs, J.
Gulick, J. Robbins, D.M. Warshaw, R. Craig. Univ. of Vermont,
Univ. of Massachusetts Med. Sch., Eulji Univ., South Korea,
Clarkson Univ. and Cincinnati Children’s Hosp. Med. Ctr.
B604 1012.3 Effect of Hypertrophic CardiomyopathyAssociated R282W Mutation of MYBPC3 on M-Domain
Phosphorylation In Vitro. A.M. Giuffre, T.L. Lynch IV, N.
Sadagopan, S. Sadayappan. Loyola Univ. Chicago.
B605 1012.4 A Role for the Transient Receptor Potential
Vanilloid 4 Channel in Modulating Uterine Tone during
Pregnancy. L. Ying, C.M. Alvira, D.N. Cornfield. Stanford Univ.
1013.SMOOTH MUSCLE
Poster
Exhibit Halls A-D
B606 1013.1 Pharmacological Opening of Kv7 Channels
by the Novel Activator ML-213: Role in Guinea Pig Urinary
Bladder Smooth Muscle Function. A. Provence, K.L. Hristov,
G.V. Petkov. Univ. of South Carolina.
B607 1013.2 Testosterone Regulates Urinary Bladder
Smooth Muscle Function through a Signaling Mechanism
Involving Direct Activation of Large Conductance Voltage- and
Ca2+-Activated K+ Channels. K.L. Hristov, S.P. Parajuli, G.V.
Petkov. Univ. of South Carolina.
B608 1013.3 Transient Receptor Potential Melastatin 4
Channel Regulation by Inositol Trisphosphate Receptor in
Human Urinary Bladder Smooth Muscle. A. Provence, K.L.
Hristov, E.S. Rovner, G.V. Petkov. Univ. of South Carolina and
Med. Univ. of South Carolina.
B609 1013.4 High-Throughput Contractile Force Screening
for Discovery of Novel Bronchodilators. C. Park, S. Burger,
E. Watts, M. Frykenberg, D. Tambe, E. Zhou, R. Krishinan,
A. Marinkovic, D. Tschumperlin, J. Butler, J. Solway, J.
Fredberg. Harvard T.H.Chan Sch. of Publ. Hlth., Univ. of South
Alabama, Beth Israel Deaconess Med. Ctr., Mayo Clin. and
Univ. of Chicago.
B610 1013.5 Ablation of the Semaphorin 3F-Neuropilin 2
Axis Increases Contractility in Bladder Smooth Muscle. D.R.
Bielenberg, E. Vasquez, C. Doyle, S. Lukianov, V. Cristofaro,
M.P. Sullivan, R.M. Adam. Harvard Med. Sch., Boston
Children’s Hosp. and VA Boston Healthcare Syst.
B611 1013.6 Essential Roles of ANO1 in Mouse Urethral
Smooth Muscle Contraction and Urinary Continence. M. Feng,
D. Liu, P. Lu, K. Bellve, L.M. Lifshitz, K. Fogarty, R. ZhuGe.
Univ. of Massachusetts Med. Sch.
MONDAYPHYSIOLOGY
1014.EXERCISE, MUSCLE, AND BONE
1015.MITOCHONDRIAL FUNCTION
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
B612 1014.1 HIF-1α Regulates a Single Bout of ExerciseInduced Hepatic Expression of Glucose and Lipid Metabolism
Related Genes. B. Luo, D. Xiang, P. Chen, Y. Hu. Second
Military Med. Univ., Shanghai, Shanghai Univ. of Sport and
Naval Med. Res. Inst., Shanghai.
B613 1014.2 Exercise Mitigates Cognitive Functions
through Mitochondrial Remodeling in Type-2 Diabetes. A.
Kalani, P. Chaturvedi, L.J. Winchester, S.C. Tyagi, N. Tyagi.
B614 1014.3 Roux-en-Y Gastric Bypass Surgery Enhances
Contraction-Mediated Glucose Metabolism in Primary Human
Myotubes. J.M. Hinkley, K. Zou, S. Park, K. Turner, D. Zheng,
J.A. Houmard. East Carolina Univ.
B615 1014.4 Defective Autophagy Causes a Maladaptive
Cardiac Phenotype to Exercise That Leads to Premature
Death and FGF21-Mediated Protection against Obesity and
Insulin Resistance. V.A. Lira, A. Kronemberger, J.A. Call,
H.M. Caster, R.O. Pereira, R.C. Laker, M. Zhang, Z. Yan.
Carver Col. of Med., Univ. of Iowa, Univ. of Georgia and Univ.
of Virginia.
B616 1014.5 Air Puffs as Refinement of Electric Shocks
for Stimulation during Treadmill Exercise Test. S. Lamy, C.
Cartoni, A. Bichat, R. Combe, R. Doenlen, X. Warot. Ecole
Polytech Fed. de Lausanne.
B617 1014.6 Musclin – A Novel Exercise Factor. E.
Subbotina, A. Sierra, Z. Zhu, Z. Gao, S. Koganti, E. Stepniak,
D. Hodgson-Zingman, L. Zingman. Univ. of Iowa and Univ.
of Chicago.
B618 1014.7 Myostatin Protein and Muscle Fiber CrossSectional Area Are Associated with Increased Muscle Satellite
Cell Number in 10 Month Old Fisher 344 Rats Treated with
Testosterone and Trenbolone Enanthate. D.T. Beck, V.J.
Dalbo, C.B. Mobley, C. Ballmann, W.C. Kephart, C.D. Fox,
V.A. Santucci, L.A. Beggs, A. Balaez, F.J. Hoerr, J.F. Yarrow,
S.E. Borst, M.D. Roberts. Edward Via Col. of Osteo. Med.Auburn Campus, Auburn Univ., Central Queensland Univ.,
Univ. of Florida, Malcom Randall VA Med. Ctr., Gainesville, FL
and Vet. Diagnostic Pathol. LLC, Auburn.
B619 1014.8 3D Virtual Histology of Trabecular and Cortical
Architecture in Living Human Vertebrae. H. Tanioka, K. Kaga.
Tanioka Clin. and Natl. Inst. of Sensory Organs, Tokyo.
B620 1014.9 The Activation on Serotonin 2B Receptor
Is Essential for Osteoclastogenesis. Y-C. Huang, S-Y. Lin,
T-S. Lu, B. Huang, C-L. Lin, Y-S. Fu. Kaohsiung Med. Univ.,
Taiwan, Brigham and Women’s Hosp., Harvard Med. Sch. and
Kaohsiung Med. Univ. Hosp.
B621 1014.10 Integrin-Linked Kinase Enhances Skeletal
Muscle Fatty Acid Metabolism In Vivo. D.S. Lark, E. Trefts, M.
James, R. Zent, A. Pozzi, D.H. Wasserman. Vanderbilt Univ.
Med. Ctr. and Mouse Metab. Phenotyping Ctr.
B622 1015.1 Time-Dependent Differential Effects of
Fasting on Cardiac Autophagy and Mitophagy. U. Aslam, S.
Kobayashi, Q. Liang, M. Gerdes. New York Inst. of Technol.
Col. of Osteo. Med.
B623 1015.2 The Role of Mitophagy in Doxorubicin-Induced
Cardiomyocyte Death. A. Weiner, A. Kaminaris, S. Kobayashi,
M. Gerdes, Q. Liang. NYIT Col. of Osteo. Med.
B624 1015.3 Overexpression of Muscle Ring Finger 1
Reduces Mitochondrial Volume in Cardiomyocytes. C. Parikh,
S. Kobayashi, M. Gerdes, M.S. Willis, Q. Liang. NYIT Col. of
Osteo. Med. and Univ. of North Carolina at Chapel Hill.
B625 1015.4 Mitochondrial Dynamics in Auditory Sensory
Cells. A.L. Nuttall, S. Foster, T. Wilson. Oregon Hlth. &
Sci. Univ.
B626 1015.5 The Requirement of Cytochrome c Oxidase
for Mitochondrial Fusion in Copper-Induced Regression of
Cardiomyocyte Hypertrophy. W. Yin, R. Li, X. Feng, Y.J. Kang.
West China Hosp., Sichuan Univ., China.
B627 1015.6 Chronic Binge Alcohol Administration Impairs
Skeletal Muscle Mitochondrial Gene Expression in Simian
Immunodeficiency Virus-Infected Rhesus Macaques. A.A.
Duplanty, K. Song, L. Simon, P.E. Molina. LSU Hlth. Sci. Ctr.,
New Orleans.
B628 1015.7 Skeletal Muscle Mitochondrial Function in
High-Fat Diet Fed Mice with Genetically Modified Myostatin
Expression. A.V. Khamoui, A. Abraham, S. Reisz-Porszasz,
H.B. Rossiter. LA BioMed Res. Inst. at Harbor-UCLA Med. Ctr.
and Charles R. Drew Univ. of Med. and Sci.
B629 1015.8 Altering Buffer Ca2+ and pH Stimulates
Activation of Mitochondrial Ca2+/H+ Exchanger. M.R. Boswell,
A.K.S. Camara, J.S. Heisner, M. Aldakkak, C.A. Blomeyer, M.
Yang, D.F. Stowe. Med. Col. of Wisconsin, Univ. of Wuerzburg
and Marquette Univ. and Zablocki VA Med. Ctr.
B630 1015.9 Sodium Nitrate Supplementation Does Not
Alter Mitochondrial Bioenergetics in the Heart. C.M.F. Monaco,
P.M. Miotto, G.P. Holloway. Univ. of Guelph, Canada.
B631 1015.10 Human Energy Expenditure Is in Control of
Cytochrome C Oxidase Subunit IV-2 T.A. Schiffer, B. Ekblom,
M.L. Sundqvist, J.O. Lundberg, E. Weitzberg, F.J. Larsen.
Uppsala Univ., Karolinska Inst., Swedish Sch. of Sports and
Hlth. Sci. and Karolinska Univ. Hosp., Stockholm.
B632 1015.11 Heat Shock Protein 72 Regulates Mitochondrial
Integrity and Function in the Prevention of Hepatic Insulin
Resistance. R.S. Rogers, J.L. Wheatley, A.E. Archer, J.P.
Thyfault, P.C. Geiger. Univ. of Kansas Med. Ctr.
B633 1015.12 An Investigation of the Suitability of Using
Octanoylcarnitine Together with Malate as a Substrate
Combination for Assessing Beta-Oxidation Using High
Resolution Respirometry. P.O. Osiki, E.O. Ojuka, G.J.
Maarman. Univ. of Cape Town.
B634 1015.13 Cardiac Aging Concurs with Abnormal
Mitochondrial Metabolism, Calcium Handling and Disrupted
Levels of Mitochondrial Calcium Uniporter Complex Member
Proteins. J. Suarez, J. Diaz-Juarez, B.T. Scott, A. Dai, W.H.
Dillmann. UCSD and Natl. Inst. of Cardiol., Mexico City.
337
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PHYSIOLOGYMONDAY
B635 1015.14 Effect of KATP Channel Activators and Inhibitors
on Skeletal Muscle Mitochondrial Function. E. SanchezDuarte, X. Trujillo, M. Huerta, O. Ortiz-Avila, C. Cortes-Rojo,
A. Saavedra-Molina, A. Rodriguez-Orozco, R. MontoyaPerez. Univ. of Colima, Inst. of Biochem. Res. and Fac. of
Med., Michoacana Univ. San Nicolas de Hidalgo, Mexico.
1016.NUTRITION AND NUTRIENT METABOLISM
Poster
Exhibit Halls A-D
B636 1016.1 A High Methionine, Low Folate and Low
Vitamin B6/B12 Diet Causes Neurovascular Dysfunction and
Subsequent Short-Term Memory Loss. M. Nuru, A. Kalani, N.
Muradashvili, D. Lominadze, N. Tyagi. Univ. of Louisville.
B637 1016.2 Distribution Pattern of Dietary Protein Intake
Does Not Affect Anabolic Response, Lean Body Mass, Muscle
Strength or Function Over 8 Weeks in Older Adults. I-Y. Kim, S.
Schutzler, G. Azhar, R. Wolfe, A. Ferrando. Univ. of Arkansas
for Med. Sci.
B638 1016.3 Diet Restriction Exacerbates Memory Loss in
Alzheimer’s Disease Drosophila melanogaster Model Flies.
D.J. Damschroder, B. Paddock. Arcadia Univ., PA.
B639 1016.4 Altered Metabolism in RGS2 KO Mice. K. Lee,
R. Gros, P. Chidiac. Univ. of Western Ontario.
B640 1016.5 Nutritional Status Affects Expression of AMPK
mRNA in a Tissue and Subunit-Specific Manner in Channel
Catfish. P. Evans, M. Vides, B. Teel, Y. Kobayashi. Fort Hays
State Univ.
B641 1016.6 Hypolipidemic Effects of Tomato in Rats Fed
a High-Fat Diet. M.C. Alfaro-Olivera, M.R. Calla-Pampa, L.J.
Fernández-Rodríguez. Antenor Orrego Private Univ., Peru.
B642 1016.7 Effect of Canary Grass (Phalaris canariensis)
Seed Extract on the Lipid Profile of Rats with Induced
Hyperlipidemia. A.P. Vizconde-Rodríguez, M.L. SalazarCastillo, I.M. Rodríguez-Haro, A.A. Calderón-Peña, L.J.
Fernández-Rodríguez. Antenor Orrego Private Univ., Trujillo
and Natl. Univ. of Trujillo, Peru.
B643 1016.8 The Effects of Anti-fibroblast Growth Factor
23-Peptides Antibodies on Excreta Phosphate of Chicks. Z.
Ren, D.E. Butz, M. Ebrahimi, M.E. Cook. Sichuan Agr. Univ.,
China, Univ. of Wisconsin-Madison and Univ. of Tabriz, Iran.
1017.INNATE IMMUNE FUNCTIONS OF INTESTINAL
EPITHELIAL CELLS
Poster
Exhibit Halls A-D
B644 1017.1 Loss of PTPN2 in Intestinal Epithelial Cells
Upregulates a Novel STAT-Dependent Mechanism of
Claudin-2 Expression. M. Krishnan, D.F. McCole. Univ. of
B645 1017.2 ErbB3 Negatively Regulates Homeostatic
Paneth Cell Numbers. D. Almohazey, J.J. Hsieh, C.V. Vossler,
M.R. Frey. Children’s Hosp. Los Angeles, Univ. of So. California.
338
B646 1017.3 Stressor-Enhanced Infectious Colitis Is Due
to Aberrant Colonic Epithelial Cell Signaling. A. Mackos, M.T.
Bailey. Nationwide Children’s Hosp. Res. Inst. and The Ohio
State Univ.
B647 1017.4 Intestinal Mucus Acts Is a Maturation Factor
for Dendritic Cells. M.A. Engevik, R.S. Fultz, B.P. Ganesh, J.
Versalovic. Baylor Col. of Med.
B648 1017.5 The Effect of JAK-Inhibitor Tofacitinib on
Intestinal Epithelial Barrier Function. A. Sayoc, M. Krishnan,
D.F. McCole. Univ. of California, Riverside.
B649 1017.6 Intestinal Epithelial IL-15 Overexpression
Enhances γΔ T Cell Mucosal Surveillance. K.L. Edelblum, B.
Jabri, J.R. Turner. Rutgers New Jersey Med. Sch. and Univ.
of Chicago.
1018.EFFECTS OF DIET AND METABOLITES ON
MUCOSAL IMMUNOLOGY
Poster
Exhibit Halls A-D
B650 1018.1 hdcA+ L. reuteri 6475 Inhibits H1R Downstream
Signaling via dagK and Causes Immunosuppression of
Intestinal Epithelium in Gnotobiotic Mice. B.P. Ganesh, A. Hall,
R. Fultz, M. Engevik, M. Whary, J. Fox, J. Versalovic. Baylor
Col. of Med. and MIT.
1019.GASTROINTESTINAL CANCER
AND METASTASIS
Poster
Exhibit Halls A-D
B651 1019.1 Emerging Regulatory Roles of Wnt1 In HostPathogen Interactions in Inflammation and Colon Cancer. X.
Liu, H. Chen, Y. Zhang, R. Lu, Q. Liu, J. Sun. Nanjing Med.
Univ., China, Albert Einstein Col. of Med. and Univ. of Illinois
at Chicago.
1020.GASTROINTESTINAL NUTRIENT SENSORS
Poster
Exhibit Halls A-D
B652 1020.1 FFA3
Activation
Stimulates
Duodenal
Bicarbonate Secretion and Prevents NSAID-Induced
Enteropathy via the GLP-2 Pathway in Rats. H. Said, Y. Akiba,
I. Kaji, J.D. Kaunitz. UCLA and West Los Angeles VA Med. Ctr.
B653 1020.2 Nutrient Sensing in Atlantic Salmon – Exploring
the Sensory Systems for Amino Acids in the Gastrointestinal
Tract. I. Ronnestad, A-E.O. Jordal, A.S. Gomes. Univ. of
Bergen, Norway.
MONDAYPHYSIOLOGY
B654 1020.3 Butyrate Enhances MCT1 Association with
CD147 via GPR109A Activation-Dependent Mechanisms. I.
Chatterjee, A. Kumar, A.N. Anbazhagan, W.A. Alrefai, A.
Borthakur, P.K. Dudeja. Univ. of Illinois at Chicago and Jesse
Brown VA Med. Ctr.
1021.GI HORMONES, PEPTIDES AND RECEPTORS
Poster
Exhibit Halls A-D
B655 1021.1 Serotonin Type 3 Receptor B Subunit and
Corticotropin-Releasing Hormone Expression in the Serotonin
Transporter Knockout Rat Model of Visceral Hypersensitivity.
A. Mecca, N. El-Ayache, J. Galligan. Michigan State Univ.
B656 1021.2 Elucidating Interactions between Human MasRelated G-Protein Coupled Receptors. S. Van Remoortel,
R. Arora, A.J. Labro, D.J. Snyders, R. Buckinx, J-P.
Timmermans. Univ. of Antwerp.
B657 1021.3 A GLP-1 Mimetic Alleviates Irritable Bowel
Syndrome-Like Symptoms in the Wistar Kyoto Rat. R. O’Brien,
M.M. Buckley, K.D. O’Halloran, D. O’Malley. University Col.
of Cork.
1022.IMMUNOLOGY AND MICROBIOLOGY OF
THE GUT
Poster
Exhibit Halls A-D
B658 1022.1 Lactobacillus rhamnosus Isolated from
“amabere amaruranu” Cultured Milk Modulated the Production
of Inflammatory Cytokines in Caco-2 Cells. B. Ngeny, E.M.
Onyango. East Tennessee State Univ.
B659 1022.2 Modulation of CD4+ T Cell Differentiation by
the Probiotic Lactobacillus reuteri F. Collins, R.A. Britton, L.R.
McCabe, N. Parameswaran. Michigan State Univ. and Baylor
Col. of Med.
1023.INTESTINAL INFLAMMATION
AND PATHOPHYSIOLOGY
Poster
Exhibit Halls A-D
B660 1023.1 Heightened Anaphylaxis Reaction in Female
Mice Is Associated with Increased Synthesis of Mast Cell
Secretory Granule-Associated Immune Mediators. E. Mackey,
S. D’Costa, C. Pohl, S. Ayyadurai, S. Laster, A.J. Moeser.
North Carolina State Univ., GI Stress Biol. Lab., East Lansing,
Univ. of North Carolina at Chapel Hill and Michigan State Univ.
B661 1023.2 Elevated D-2-Hydroxyglutarate during Colitis
Drives Progression to Colorectal Cancer. A. Theiss, J. Han,
R. Genta, L. Sweetman. Baylor Res. Inst. and Univ. of Texas
Southwestern Dallas VA Med. Ctr.
B662 1023.3 Tachykinin Activation on Enteric Glia: A Novel
Mechanism of Enteric Nervous System Dysfunction in Irritable
Bowel Syndrome. N.M. Delvalle-Dorta, G. Rivera-Lopez, B.
Gulbransen. Michigan State Univ. and Univ. of Puerto Rico
at Humacao.
B663 1023.4 Estrogen Receptor Beta Activation Plays a
Therapeutic Role in Murine Models of Inflammatory Bowel
Disease via Inhibiting P2X3 and P2X7 Receptors. B. Ma, Q.
Jiang, W. Li, Z. Li. Second Military Med. Univ. and Changhai
Hosp., Shanghai.
B664 1023.5 Suppressive Effect of Nicotine on Expression
of MAdCAM-1 in Colitis. K. Maruta, C. Kurihara, H.
Furuhashi, T. Takajo, Y. Yasutake, Y. Okada, K. Yoshikawa, M.
Higashiyama, C. Watanabe, S. Komoto, K. Tomita, S. Nagao,
S. Miura, R. Hokari. Natl. Defense Med. Col., Japan.
B665 1023.6 Blocking NF-κB Activation in Intestinal
Lysozyme M Positive Cells Prevents the NEC-Induced
Decrease in Ly6C Positive Cells in the Neonatal Intestine.
E. Managlia, X. Yan, X. Liu, J. Mangrum, I. De Plaen. Ann &
Robert H. Lurie Children’s Hosp. of Chicago and Northwestern
Univ., Chicago.
B666 1023.7 Regulation of the Antioxidant Glutathione
by Enteric Glia during Inflammation. I.A.M. Brown, B.D.
Gulbransen. Michigan State Univ.
B667 1023.8 Bile Acids Regulate Intestinal Epithelial
Restitution: Implications for Pathogenesis and Therapy of IBD.
N.K. Lajczak, M.S. Mroz, V. Saint-Criq, S. Keely. Royal Col. of
Surgeons in Ireland.
B668 1023.9 Transfection of Rat Intestinal Epithelial Cells
with a Stable Mitogen-Activated Protein Kinase Phosphatase-1
Mutant. M.M. Talavera, S. Crowell, L.D. Nelin, Y. Liu.
Nationwide Children’s Hosp., Columbus.
B669 1023.10 Protective Actions of 5-HT4 Receptors in
the Colonic Epithelium. S.N. Spohn, R. Scott, C. O’Neill, C.
MacNaughton, M. Dicay, F. Bianco, E. Bonora, B. Lavoie,
R.L. Wilcox, R. De Giorgio, W. MacNaughton, K.A. Sharkey,
G.M. Mawe. Univ. of Vermont, Danbury Hosp., CT, Univ. of
Calgary, Canada and Univ. of Bologna.
B670 1023.11 17β-Estradiol and Bisphenol-A Exacerbate
Symptoms of Dextran Sodium Sulfate-Induced Colitis in Mice.
J.A.A. DeLuca, K.F. Allred, A. Jayaraman, C.D. Allred. Texas
A&M Univ.
B671 1023.12 Dexamethasone
Upregulates
Human
SLC26A3 Transporter Expression in Intestinal Epithelial
Cells. A. Kumar, S. Priyamvada, I. Chatterjee, A. Natarajan
Anbazhagan, M. Singhal, A. Borthakur, S. Saksena, R. Gill,
W. Alrefai, P.K. Dudeja. Univ. of illinois at Chicago and Jesse
Brown VA Med. Ctr.
B672 1023.13 Analysis of Inflammatory Modulation on Term
and Preterm Neonatal Gastrointestinal Non-human Primate
Explants. N.B. Alana, S.J. Acevedo, N.J. Carr, S.B. Mustafa,
C.L. Blanco, J.M. King. Trinity Univ., San Antonio Military Med.
Ctr. and Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
B673 1023.14 ErbB4 Signaling Restricts Pro-inflammatory
Macrophage Numbers through an ADAN17/γ-Secretase
Dependent Mechanism. M.A. Schumacher, J.K. Bernard, J.J.
Hsieh, S. Punit, M.R. Frey. Children’s Hosp. Los Angeles and
Univ. of So. California.
B674 1023.15 Metformin Enhances Intestinal Epithelial
Health through Activation of AMPK. Y. Xue, X. Sun, M-J. Zhu.
Washington State Univ. and Univ. of Idaho.
339
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1024.LIVER PHYSIOLOGY AND PATHOPHYSIOLOGY
Poster
Exhibit Halls A-D
B675 1024.1 Activation of Nlrp3 Inflammasomes in Mouse
Hepatic Stellate Cells during Schistosoma J. Infection. N. Meng,
M. Xia, P-L. Li, W-X. Tang. Virginia Commonwealth Univ. and
Tongji Med. Col., Huazhong Univ. of Sci. and Technol., China.
B676 1024.2 Zinc Deficiency Contributes to Alcohol
Consumption-Induced Defect of Mitochondrial Electron
Transport Chain and Overproduction of Reactive Oxygen
Species in the Live of Rats. Q. Sun, W. Zhong, W. Zhang, X. Sun,
Z. Zhou. Univ. of North Carolina at Greensboro, Kannapolis.
1025.METABOLIC DISEASE: GI AND
LIVER FUNCTION
Poster
Exhibit Halls A-D
B677 1025.1 Liver-Directed Knockout and Transgene
Delivery of Arginase-1 in Mice. C.D. Funk, L. Ballantyne,
A. Schulze. Queen’s Univ., Canada and The Hosp. for Sick
Children, Toronto.
B678 1025.2 Live Imaging of Hepatic and Intestinal
Intracellular ApoA-I in Zebrafish. J.P. Otis, B.A. Caldwell,
P.N. Howles, S.A. Farber. Carnegie Instn., Baltimore, Univ. of
Cincinnati and Johns Hopkins Univ.
B679 1025.3 Long-Term Adaptations in Hepatic Substrate
Utilization in 1 Year Old Rat Model of Bronchopulmonary
Dysplasia. T.S. Levin, L. Tetri, K. Haraldsdottir, D.F.
Pegelow, R.K. Braun, K.N. Gross, M.W. Eldridge. Univ.
1026.METAL ION TRANSPORT
Poster
Exhibit Halls A-D
B680 1026.1 Mechanism
of
Copper
Uptake
from
Ceruloplasmin by Cells and the Involvement of an Additional
Copper Uptake Transporter. L. Dinh, J. Juarez, R. Vargas,
D. Ramos, D. Mar, M. Ishida, M.C. Linder. California State
Univ. Fullerton.
B681 1026.2 Purification and Characterization of a Small
Copper Carrier Found in Mammalian Blood Plasma and in the
Urine of Mice and Dogs with Copper Overload. M. Tellez, T.
Alsky, M. Dalphin, S. Flynn, A. Munoz, D. Ibarra, H. Truong,
M.C. Linder, S. Lutsenko, S. Weldy. California State Univ.
Fullerton, Johns Hopkins Univ. and Serrano Animal and Bird
Hosp., Lake Forest, CA.
340
B682 1026.3 Arsenic and Copper Serve as Cofactors to
Produce Hepatotoxicity with Mitochondrial Damage, Double
Strand DNA Breaks and Disruption of ATM Signaling. T.
Chinnasamy, Y. Sharma, P. Gupta, S. Gupta. Albert Einstein
Col. of Med. and Pondicherry Univ., India.
1027.MICROBIOME OF THE GI TRACT
Poster
Exhibit Halls A-D
B683 1027.1 Bifidobacterium
dentium
Modulates
Expression of Genes Important to Synaptic Plasticity and
Neurodevelopment in the Cerebellum of Germ-Free Mice. B.
Luk, M. Engevik, A. Hall, J. Versalovic. Baylor Col. of Med.
and Texas Children’s Hosp.
B684 1027.2 Alterations in the Gut Microbiome Can Elicit
Hypertension in WKY Rats. S. Adnan, J.W. Nelson, D.J.
Durgan, R.M. Bryan. Baylor Col. of Med.
B685 1027.3 Repeated Antibiotic Treatment Affects Social
Behaviors in Siberian Hamsters (Phodopus sungorus) K.E.
Sylvia, N.M. Rendon, E.A. St. John, G.E. Demas. Indiana Univ.
B686 1027.4 Effects of a Broad-Spectrum Antibiotic on the
Siberian Hamster (Phodopus sungorus ) Gut Microbiome. E.A.
St. John, K.E. Sylvia, G.E. Demas. Indiana Univ.
B687 1027.5 Cardiorespiratory Fitness as a Predictor
of Intestinal Microbial Diversity and Distinct Metagenomic
Functions. M. Estaki, J. Pither, P. Baumeister, J.P. Little, S.
Gill, S. Ghosh, Z. Ahmadi-Vand, K.R. Marsden, D.L. Gibson.
Univ. of British Columbia Okanagan.
B688 1027.6 Depletion of Murine Microbiota with BroadSpectrum Antibiotics Alters Intestinal Motility, Secretion, and
Mucosal Barrier Function. J. Lendrum, B. Seebach, S. Liu.
Univ. of Wisconsin-La Crosse.
B689 1027.7 Amoxicillin Decreases Intestinal Microbial
Diversity and Increases Stress-Associated Behaviors in
Zebrafish. K.L. Deprey, J.K. Uno. Elon Univ.
B690 1027.8 IBS-Induced Constipation Alters Gut Microbiota
Stability Leading to Intestinal Transit Time Changes in the Host.
K. Touw, A. Nadimpalli, N. Hubert, V. Leone, P. Kashyap, E.
Chang. Univ. of Chicago and Mayo Clin.
1028.GENE EDITING, NON-CODING RNA, AND
SYSTEMS BIOLOGY
Poster
Exhibit Halls A-D
B691 1028.1 The Baylor KOMP2 Program and BaSH
Consortium: A Resource for Producing and Phenotyping
Knockout Mice. C.L. Reynolds, A. Beaudet, M. Dickinson, J.
Seavitt, J. Heaney. Baylor Col. of Med.
B692 1028.2 Variation in Exercise Capacity and Responses
to Training in Inbred Mouse Strains. M.P. Massett, J.J. Avila,
S.K. Kim. Texas A&M Univ.
MONDAYPHYSIOLOGY
B693 1028.3 Vitamin D Supplementation and DNA
Methylation Patterns during Pregnancy and Lactation in
Mothers and Infants. C.M. Anderson, D.K. Thiele, J.L. Ralph,
D. Perley, J.E. Ohm. Col. of Nursing, The Ohio State Univ.,
Sch. of Nursing, Oregon Hlth. & Sci. Univ. and Col. of Nursing
and Prof. Disc. and Sch. of Med. and Hlth. Sci., Univ. of
North Dakota.
B694 1028.4 Comparative Analysis of Methods to Profile
mRNA Expression of G-Protein Coupled Receptors. K. Sriram,
S. Zhou, A.M. Lowy, P.A. Insel. UCSD and UCSD Sch. of Med.
B695 1028.5 The Essence of Quiescence: Understanding
the Roles of Histone Modification H4K20me3 and the Histone
Modifying Enzyme Suv4-20h2 in Cellular Quiescence. A.Z.
Corvalan, A.G. Evertts, W.E. Lowry, H.A. Coller. UCLA and
Princeton Univ.
B696 1028.6 Survey on microRNAs Targeting MuRF1 and
MuRF2 in Regenerating Skeletal Muscle. W.J. Silva, I.L.
Baptista, J.G. Silvestre, C.I. Yan, A.S. Moriscot. Inst. of
Biomed. Sci., Univ. of São Paulo.
B697 1028.7 LncRNA H19
Inhibits
Gut
Epithelial
Regeneration via Wnt Co-receptor LRP6 by Interacting with
RNA-Binding Protein HuR. G. Chen, J.N. Rao, T. Zou, L. Xiao,
H.K. Chung, M. Gorospe, J-Y. Wang. Univ. of Maryland Sch.
of Med. and NIA, NIH, Baltimore.
B698 1028.8 miR-145 Targets the 3′ UTR of Cited2 and Is
Reduced by Myostatin in C2C12 Cells. Z.A. Graham, R. de
Gasperi, W.A. Bauman, C.P. Cardozo. James J. Peters VA
Med. Ctr., Bronx and Icahn Sch. of Med. at Mt. Sinai.
B699 1028.9 Role of lncRNAs in Regulating Endothelial
Function. T-S. Huang, K-C. Wang, J.Y-S. Li, T-Y. Chang, S.
Subramaniam, J. Shyy, H-W. Wang, S. Chien. Sch. of Med.,
UCSD and Natl. Yang-Ming Univ., Taiwan.
B700 1028.10 The MicroRNA let-7f Regulates Expression
of the Voltage-Gated Mechanosensitive Ion Channel NaV1.5
in Human Gastrointestinal Smooth Muscle. A. Mazzone, P.R.
Strege, C.E. Bernard, R.R. Cima, D.W. Larson, E.J. Dozois,
Y. Hayashi, T. Ordog, S.J. Gibbons, A. Beyder, G. Farrugia.
Mayo Clin.
B701 1028.11 MiR9 Is Increased in Rheumatoid Arthritis
Monocytes and Regulates Monocyte Migration. J. Gaudette,
W.A. Stinson, D.A. Fox, M.A. Amin, B.J. Rabquer. Albion Col.
and Univ. of Michigan.
B702 1028.12 MicroRNA Profiling and Regulation in
Hypertensive Kidney. G. Weber, S. Pushpakumar, M.
Mukhopadhyay, U. Sen. Univ. of Louisville.
B703 1028.13 miR429 Is Upregulated in Inflammatory
Monocytes and Regulates Monocyte Migration. Z.R. Barry,
R.W. Kynast, W.A. Stinson, D.A. Fox, M.A. Amin, B.J.
Rabquer. Albion Col., MI and Univ. of Michigan.
B704 1028.14 MicroRNAs Target Decidual Angiogenic
Factors during Early Pregnancy in BPH/5, a Spontaneous
Mouse Model of Preeclampsia. J. Xia, S. Baxter, J. Grenier,
R.L. Davisson, J.L. Sones. Cornell Univ.
M
O
N
341
TUESDAY, APRIL 5
Anatomy
1029.DEVELOPMENT AND GROWTH: NEURAL
CREST AND PLACODES
1031.DEVELOPMENT AND
GROWTH: ORGANOGENESIS
Poster
Poster
Tue. 9:00 am—San Diego Convention Center,
Exhibit Halls A-D
Exhibit Halls A-D
A259 1029.1 Molecular Changes Leading to the Abnormal
Migration of Sacral Neural Crest Cells in the Dominant
megacolon Mutant, a Mouse Model of Hirschsprung’s Disease.
T. Huang, Y. Hou, W.Y. Chan. Sch. of Biomed. Sci., The
Chinese Univ. of Hong Kong.
A260 1029.2 The Effect of Phenylalanine Exposure on Cell
Migration. M.B. Vaughan, N.J. Alkadhem, N.J. Seagraves.
Univ. of Central Oklahoma and Al Nahrain Univ.
A261 1029.3 Cranial Neural Crest Migration Sculpts
Endothelial Patterning in Avians with Anti-angiogenic Factors.
M.C. McKinney, P. Kulesa. Stowers Inst. for Med. Res.,
Kansas City, MO. (83.2)
1030.DEVELOPMENT AND GROWTH: CRANIOFACIAL
A266 1031.1 Deletion of Notch Signaling in the Developing
Mouse Kidney Results in a Disruption of Planar Cell Polarity in
Tubule Epithelial Cells. D. Kearns, S. Livingston, R. Baybutt,
G. Vanden Heuvel. Wheaton Col., IL and Western Michigan
Univ. Sch. of Med.
A267 1031.2 Mechanics of Cell Motility within Stratified
Epithelia. A. Czirok, D.G. Isai, Z. Neufeld. Univ. of Kansas
Med. Ctr. and Queensland Univ., Australia.
A268 1031.3 An Active Microrheological Approach to
Determine Material Properties of Early Avian Embryos. E.
Kosa, Z. Akos, M. Filla, D.G. Isai, S. Ghazvini, P. Dhar, A.
Czirok. Univ. of Kansas Med. Ctr., Children’s Hosp. Los
Angeles and Univ. of Kansas.
1032.DEVELOPMENT AND GROWTH: LIMBS
Poster
Exhibit Halls A-D
A262 1030.1 Role of Skeletal Muscle in Inner Ear
Development. I. Rot, B. Kablar. Dalhousie Univ., Canada.
A263 1030.2 The Otolithic Membrane Mediates Otolith
Organization. K.L. Kramer, K.D. Thiessen. Creighton Univ.
A264 1030.3 Inner Ear Volume in Craniosynostotic Mice.
E.A. Heitman, M.A. Holmes, M.A. McNulty, V.B. DeLeon, J.C.
Mussell. Sch. of Med., LSU Hlth. Sci. Ctr., New Orleans, Duke
Univ. Sch. of Med., LSU Sch. of Vet. Med., Baton Rouge and
Univ. of Florida.
A265 1030.4 Ontogeny and Microanatomy of the Nasal
Turbinals in Four Genera of Lemuriformes. T.D. Smith, M.C.
Martell, J.B. Rossie, V.B. DeLeon. Sch. of Phys. Therapy,
Slippery Rock Univ., Univ. of Pittsburgh, Univ. of Florida and
SUNY Stony Brook.
342
Poster
Exhibit Halls A-D
A269 1032.1 Low Dose IGF-I Augments the BoneLengthening Effect of Targeted Heat in the Mouse Hindlimb.
M.A. Serrat, H.L. Racine, G. Ion, J.C. Kerby, C.A. Meadows.
Marshall Univ. Joan C. Edwards Sch. of Med.
A270 1032.2 Thermal Imaging Reveals Temperature
Retention in Hindlimbs of Mice Up to 4 Hours after Targeted
Intermittent Limb Heating. H.L. Racine, G. Ion, J.C. Kerby,
M.X. Gray, C.A. Meadows, M.A. Serrat. Marshall Univ. Joan
C. Edwards Sch. of Med.
A271 1032.3 Co-incident Upregulation of Shh and Hoxa 13
by Fgf in the Developing Limb Bud. D. Real, B.A. Watson, J.M.
Feenstra, C.U. Pira, K.C. Oberg. Loma Linda Univ. Sch. of
Med. and Loma Linda Univ.
A272 1032.4 Lmx1b Binds to a Gdf5-Associated Enhancer
Element Active during Limb Dorsalization. E. Haro, L. Pernu,
C.U. Pira, K.C. Oberg. Loma Linda Univ. and Walla Walla Univ.
A273 1032.5 Lmx1b-Mediated
Limb
Dorsalization:
Identification of a Potential Regulatory Sequence for Keratocan,
Lumican, and Decorin. R.N. Spady, E. Haro, C.U. Pira, J.M.
Feenstra, K.C. Oberg. Loma Linda Univ.
TUESDAYANATOMY
1033.DEVELOPMENT AND
GROWTH: REPRODUCTION
Poster
Exhibit Halls A-D
A274 1033.1 Musculoskeletal and Neural Comparison of
Normal and Abnormal Development in Humans and Broader
Medical Implications. M. Alghamdi, C. Smith, J. Ziermann, R.
Diogo. Howard Univ.
A275 1033.2 Uterine Endometrial Reprogramming during
Early Pregnancy Is Accompanied by Distinct Spatiotemporal
Expression Patterns of Basement Membrane Components.
C.R. Jones-Paris, S. Paria, T. Berg, J. Saus, G. Bhave, B.C.
Paria, B. Hudson. Vanderbilt Univ. Med. Ctr. and Valencia
Univ. Med. Sch.
A276 1033.3 Differential Changes in Trophoblast Lineage
Allocation in Rats Deficient in Uterine Natural Killer Cells.
S.J. Renaud, R.L. Scott, D. Chakraborty, M.A.K. Rumi, M.J.
Soares. Univ. of Western Ontario and Univ. of Kansas Med. Ctr.
A277 1033.4 Receptors for Advanced Glycation EndProducts (Rage) Inhibition Protects from Intrauterine Growth
Restriction (Iugr) during Second Hand Smoke (Shs) in Mice.
C.J. Jordan, J.B. Lewis, J.S. Bodine, A.L. Lewis, T.M.
Dunaway, K.M. Egbert, T.D. Monson, C. Ogden, T.J. Wright,
C.A. Mejia, P.R. Reynolds, J.A. Arroyo. Brigham Young Univ.
1034.CELL BIOLOGY: MEMBRANES,
CYTOSKELETON, CELL ADHESION
AND SIGNALING
Poster
Exhibit Halls A-D
Cell Biology
A278 1034.1 Identification and Characterization of a Novel
Actin-Associated Protein Recruited to Structures at the
Plasma Membrane. M.D. Chua, J.A. Guttman. Simon Fraser
Univ., Canada.
A279 1034.2 Functional Characterization of SM22 during
Listeria monocytogenes Infections. K.J. Hipolito, M.D. Chua,
J. Solway, J.A. Guttman. Simon Fraser Univ., Canada and
Univ. of Chicago.
A280 1034.3 Cell Contractility-Driven Multicellular Nodule
Formation. D.G. Isai, J. Zach, E. Mehes, S. Paku, B. Hegedus,
B. Dome, A. Czirok. Univ. of Kansas Med. Ctr, Eotvos Univ. and
Semmelweis Med. Univ., Hungary and Med. Univ. of Vienna.
A281 1034.4 The Non-receptor Tyrosine Kinase, Src, and
Its Regulator PTP1B Are Present at Tubulobulbar Complexes.
C.D. Ho, K.R.P. Lyon, A.W. Vogl. Univ. of British Columbia.
A282 1034.5 Sarco/Endoplasmic Reticulum Ca2+-ATPase
2 Is Present at Tubulobulbar Complexes. K.R.P. Lyon, A.W.
Vogl. Univ. of British Columbia.
A283 1034.6 Immunoelectron Microscopy of Endocytosis
and Junction Proteins at Tubulobulbar Complexes in
the Mammalian Testis. A. Adams, A.W. Vogl. Univ. of
British Columbia.
A284 1034.7 The Role of Nanoscale Roughness on Cell
Attachment following Titanium-Based Instrumentation of
Titanium, Titanium-Zirconium, and Zirconia Surfaces. D.R.
Cerutis, N.G. Fischer, R. Gnabasik, M.S. Lang, A. Baruth.
Creighton Univ.
A285 1034.8 Evidence That Epithelial Tight Junctions Are
Altered during Edwardsiella Infections. P. Aggarwal, K.Y.
Leung, J.A. Guttman. Simon Fraser Univ. and Trinity Western
Univ., Canada.
A286 1034.9 The Effects of Staphylococcus aureus Biofilm
Conditioned Medium on Fibroblast Tension Generation and
Migration. P. Kshetri, R.E. Brennan, M.B. Vaughan. Univ. of
Central Oklahoma.
A287 1034.10 Effects of Staphylococcus aureus Biofilm
and Planktonic Secreted Products on Myofibroblast
Differentiation. P.M. Hall, R.E. Brennan, M.B. Vaughan. Univ.
of Central Oklahoma.
A288 1034.11 The Effect of n-Acetylcysteine on the Migration
of Myofibroblasts. M.D. Nichols, M.B. Vaughan. Univ. of
Central Oklahoma.
A289 1034.12 Caffeine Inhibits Dupuytren’s Fibroblast Form
and Function In Vitro. J.C. Pantoja, M. Bryson, N. Alkadhem,
M.B. Vaughan. Univ. of Central Oklahoma.
A290 1034.13 Phenformin
Inhibits
Myofibroblast
Differentiation in Dupuytren’s Contracture Cells Treated
with TGF-β1 R.A. McNamar, M.B. Vaughan. Univ. of
Central Oklahoma.
A291 1034.14 Effect of ADAM17 on EMMPRIN Expression
after Vesicant Injury to the Cornea. M.K. Gordon, A. DeSantisRodrigues, Y. Chang, R.A. Hahn, P. Zhou, N.D. Heindel, D.R.
Gerecke, K.K.H. Svoboda. Ernest Mario Sch. of Pharm.,
Rutgers Univ., Lehigh Univ. and Texas A&M Baylor Col. of Dent.
A292 1034.15 Bcl-xL-c-FLIPpL Anti-apoptotic Interaction
in Microvascular Endothelial Cells. D.A. Sawant. Alderson
Broaddus Univ. Col. of Med. Sci.
A293 1034.16 The Role of HFE in Macrophages. A. Nixon, E.
Neely, J. Connor. Penn State Col. of Med.
A294 1034.17 Impact of BMP-7 on Cell Migration in the
Meniscus. V. Taylor II, I. Hutchinson, K. Danelson, C.
Ferguson. Wake Forest Med. Ctr. and Hosp. for Spec. Surg.,
NY. (9.3)
1035.MUSCLE: ANATOMY DEVELOPMENT
AND EVOLUTION
Poster
Exhibit Halls A-D
Bones/Muscle/Connective Tissue
A295 1035.1 Development of the Epaxial Muscles in
the Human Embryo. H.K. Mekonen, J.P.J.M. Hikspoors,
G. Mommen, S.E. Köhler, W.H. Lamers. Maastricht
Univ., Netherlands.
343
T
U
E
ANATOMYTUESDAY
A296 1035.2 Hindlimb Muscles of 17.5-18.5 dpc Mice
Double Null for MyoD and Trp53 Appear Indistinguishable from
Muscles of Mice Null for Either Gene. C.H. Im, K. Chau, M.
Lopez, X.Z. Sun, J. Tran, S. Cuya, S.B. Sharp. Cal State LA.
A297 1035.3 The Cardiopharyngeal Field and Associated
Syndromes in Humans. A. Forrester, F. Fahimuddin, S.
Singh, J.M. Ziermann. Howard Univ. Col. of Med.
A298 1035.4 Evaluation of the Relationships between
Anatomical Variations of the Pronator Teres and Pronator
Quadratus. L. Trimble, C. Lewis. Samuel Merritt Univ.
A299 1035.5 The Ligamentous Connection between the
Anterior Belly of the Digastric Muscle and the Mylohyoid. J.V.
Swearingen, K.D. Miller, M.J. Zdilla, H.W. Lambert. West
Virginia Univ. Sch. of Med. and West Liberty Univ.
1036.STEM CELLS, TISSUE ENGINEERING, WOUND
HEALING AND REGENERATION
Poster
Exhibit Halls A-D
Stem Cells/ Regeneration
Regenerative Medicine (Stem Cells, Tissue
Regeneration, Biomaterials)
A300 1036.1 Therapeutic Potential of Mesenchymal Stem
Cells on Chemically-Induced Arthritis in Rats: Role of Proinflammatory and Pain-Mediating Cytokines. H. Atta, A.
Noorwali, T. Bashah, A. Ganem. King Abdulaziz Univ., Saudi
Arabia and Fac. of Med., Cairo Univ.
A301 1036.2 Premature Ovarian Failure Patient-Specific
Induced Pluripotent Stem Cells Show Compromised Potential
to Develop to Germ Cells and Granulosa Cells. C-Y. Lu,
Y-A. Chen, F-C. Wu, N-S. Chang, H-N. Ho, H-F. Chen. Natl.
Taiwan Univ. Col. of Med. Grad., Taipei and Natl. Cheng Kung
Univ., Tainan.
A302 1036.3 Investigation of Anterior Cruciate Ligament
Fibroblast Biomarkers for Cell Characterization by
Immunohistochemistry. T. Lerma, G.D. Guttmann. Univ. of
North Texas Hlth. Sci. Ctr.
A303 1036.4 Mustard Injured Skin: Are Matricellular Proteins
Involved in the Delay of Wound Repair? Y-C. Chang, R.
Hahn, H-Y. Chang, P. Zhou, K.K.H. Svoboda, M. Gordon, D.
Gerecke. Rutgers Univ., Piscataway and Texas A&M Univ.,
Baylor Col. of Dent.
A304 1036.5 Olive Oil Administration Improves Cutaneous
Wound Healing of Pressure Ulcers in Mice. A. Monte Alto
Costa, A. Donnato-Trancoso, B. Romana-Souza. Rio de
Janeiro State Univ.
A305 1036.6 Using Rabbit Umbilical Cord Stem Cells as
Vehicle to Deliver Anti-cancer Drugs to Treat Pancreatic
Cancer. C. Marolt, R.S. Rachakatla. Kirksville Col. of Osteo.
Med., A.T. Still Univ.
A306 1036.7 Investigation of Blood Cell Populations in the
Development and Regeneration of a Colonial Ascidian. T.
Houck, M. Boyd, E. Balde, E. Keeling. Cal Poly State Univ.,
San Luis Obispo.
344
A307 1036.8 An In Silico Model of Xenobiotic Distribution
and Metabolism in a Simulated Mouse Hepatic Lobule. X. Fu,
J.P. Sluka, S. Clendenon, J.A. Glazier, Z. Wang, J. Klaunig,
J. Ryan, K. Dunn. Indiana Univ. Bloomington and Indiana
Univ. Indianapolis.
A308 1036.9 Potential Mechanisms of Action for Exogenous
Ketone Enhancement of Ischemic Wound Healing in Young
and Aged Fischer Rats. S.L. Kesl, M. Wu, L.J. Gould, D.P.
D’Agostino. Morsani Col. of Med., Univ. of South Florida. (9.4)
1037.BONES, CARTILAGE AND TEETH: ANATOMY
AND MORPHOLOGY
Poster
Exhibit Halls A-D
A309 1037.1 An Anatomical Study of the Trabecular Bone
Density Distribution in the Scapula Adjacent to the Glenoid
Fossa. M. Daalder, G. Venne, M. Rainbow, T. Bryant, R.T.
Bicknell, L. MacKenzie. Queen’s Univ., Canada.
A310 1037.2 Trabecular Mapping of the Human Distal
Femur: Leveraging Geometric Morphometrics for Studies of
Bone Microstructure. A.D. Sylvester. Johns Hopkins Univ.
Sch. of Med.
A311 1037.3 Quantification of the 3D Orientation of Vascular
Canals in Cortical Bone. I.V. Pratt, D.M.L. Cooper. Univ.
of Saskatchewan.
A312 1037.4 Comparative
Examination
of
Forelimb
Skeletons of Deer in South Korea. D. Ahn, J. Sim, B-Y. Park,
I-S. Kim. Col. of Vet. Med., Chonbuk Natl. Univ. and Col. of
Med. Sci., Jeonju Univ., South Korea.
A313 1037.5 Thoracic Vertebral Morphology and Locomotor
Adaptation in Anthropoid Primates. B.D. Sarrazin, E.R.
A314 1037.6 Sternum
Morphology
and
Locomotor
Adaptation in Anthropoid Primates. M.T. Alwell, E.R.
A315 1037.7 Havers-Halberg Rhythms in Canis familiaris R.
Hogg, T. Bromage, B. Hu. Florida Gulf Coast Univ. and New
York Univ. Col. of Dent.
1038.BONES, CARTILAGE AND
TEETH: CRANIOFACIAL
Poster
Exhibit Halls A-D
A316 1038.1 Cranial Index and Pattern of Head Shapes
in Children Aged 0 - 36 Months from Sokoto, Nigeria. M.A.
Musa, A.D. Zagga, M. Danfulani, A. Hamid, J.D. Usman,
A. Abdulhameed, M. Dahiru. Usmanu Danfodiyo Univ.,
Sokoto, Nigeria.
TUESDAYANATOMY
A317 1038.2 Ontogenetic Shape Change in the Human
Cranial Base and Its Relationship to Positional Behavior. F.R.
McGechie. Univ. of Missouri-Columbia.
A318 1038.3 Phylogenetic Signals in the Primate Sphenoid
Bone at Birth. V.B. DeLeon, T.D. Smith. Univ. of Florida and
Slippery Rock Univ. Sch. of Phys. Therapy.
A319 1038.4 Prevalence, Size, and Shape of the Accessory
Optic Canal. H.W. Lambert, A.M. Cusick, M.J. Zdilla. West
Virginia Univ. Sch. of Med., Bellaire H.S., OH and West
Liberty Univ.
A320 1038.5 Factors Affecting Craniofacial Development
in a Mouse Model of Crouzon Syndrome. K. Brakora, C.J.
Percival, R. Green, S-G. Gong, B. Hallgrimsson, R. Marcucio.
UCSF, Univ. of Calgary, Canada and Univ. of Toronto.
A321 1038.6 Functional Cranial Joint Histology in Anas
platyrhynchos: A Window to Understand Avian Cranial Kinesis.
A.M. Bailleul, C.M. Holliday. Univ. of Missouri-Columbia.
1039.BONES, CARTILAGE AND TEETH: EVOLUTION,
DEVELOPMENT, DISEASE AND REPAIR
Poster
Exhibit Halls A-D
A322 1039.1 Evolvability and the Diversification of the
Craniofacial Skeleton in the Domesticated Pigeon (Columba
livia) M. Linde-Medina, J. Fondon, R. Marcucio, B.
Hallgrímsson, N.M. Young. UCSF, Univ. of Texas at Arlington
and Univ. of Calgary, Canada.
A323 1039.2 Expression of CGRP, Osteopontin and VEGF
in Embryonic Mouse Mandible. I. Sato, Y. Azuma, Y. Miwa, S.
Hara, M. Sunohara. The Nippon Dent. Univ. and Nippon Dent.
Univ. Hosp.
A324 1039.3 Bat Development: Interspecies Differences in
Baculum Ossification Patterns. A.N. Herdina, T.P. Nugraha, G.
Semiadi, P.H.C. Lina, L. Godlevska, B.D. Metscher. Univ. of
Vienna, Indonesian Inst. of Sci., Cibinong, Naturalis Biodiversity
Ctr., Netherlands and Natl. Acad. of Sci. of Ukraine, Kiev.
A325 1039.4 The Dual Function of Osteocytes in Both
Demineralization and Remineralization Processes during Bone
Remodeling. Y. Hui, R. Zhang, Y. Ren, Y. Liu, J. Wang, J. Feng.
Baylor Col. of Dent. and Duke Univ. Sch. of Med.
A326 1039.5 Mechanically-Induced
Osteocyte/Th17
Cell Signaling and Subsequent Osteoclast Recruitment. T.
McCumber, K. Drescher, D. Cullen. Creighton Univ.
A327 1039.6 The Effects of Body Weight Supported Physical
Activity on Joint Pain, Function and Thigh Muscle Strength in
Overweight Patients with Mild – Moderate Knee Osteoarthritis.
J. Peeler, J. Leiter, P. MacDonald. Univ. of Manitoba and Pan
Am Clin. Fndn., Winnipeg, Canada.
A328 1039.7 Production of Interleukin 1 Beta in Primary,
Serum-Free Cultures of Human Osteoarthritic Chondrocytes.
X. Lozano-Torres, A.L. Buckley, L. Miller, G. Bundens, V.
Datillo, L. Milton, K. Behling, S. Chmielewski, E. Cho, A.
Selim, M. George-Weinstein, M. D’Angelo. Philadelphia Col.
of Osteo. Med., Cooper Univ. Hosp. and Cooper Sch. of Med.
of Rowan Univ., NJ.
A329 1039.8 Extracellular Matrix Protection Factor 1, a Novel
Inhibitor of Matrix Metalloprotease 13 Is Chondroprotective
in a Serum-Free Culture Model of Primary Human Articular
Chondrocytes. A.L. Buckley, M. George-Weinstein, L. Milton,
V. Datillo, S. Goswami, X. Lozano-Torres, K. Behling, E. Cho,
S. Chmielewski, A. Selim, L. Miller, M. D’Angelo. Philadelphia
Col. of Osteo. Med., Cooper Sch. of Med. of Rowan Univ. and
Cooper Univ. Hosp., Camden, NJ.
A330 1039.9 The Effects of Genistein Treatment on the
Proximal Femur of Obese Diabetic Mice. B. Odle, N. Dennison,
L. Al-Nakash, T.L. Broderick, J.H. Plochocki. Midwestern
Univ., AZ.
A331 1039.10 Genistein Treatment Increases Resistance
to Fracture in Obese Diabetic Mice. N. Dennison, B. Odle,
L. Al-Nakash, T.L. Broderick, J.H. Plochocki. Col. of Med.,
A332 1039.11 Transdifferentiation of Chondrocytes to
Osteoblasts during Endochondral Ossification in the Healing
Mandible. S.A. Wong, D. Hu, T. Miclau, C. Bahney, R.
Marcucio. UCSF, Sch. of Dent. and Orthopaed. Trauma Inst.
A333 1039.12 Developmental and Injury-Induced EphB3
Expression in Bone. R.A.D. Kamath, M. Szczerba, L. Xiang,
M.D. Benson. Texas A&M Univ. Baylor Col. of Dent.
A334 1039.13 Effects of Zoledronate Regimen on the
Induction of BRONJ in Rats. M. Elsalanty, A. Daoudi, N.
Howie, A. Panos, Z. Kurago. Georgia Regents Univ. and Med.
A335 1039.14 Morphometric Characterization of Maxillary
and Mandibular Interdental Spaces at the Mucogingival
Junction: Implications for Safe Orthodontic Miniscrew Insertion.
J. Yang, A. Tassi, T.D. Wilson, Y. Hosein, K. Galil. Western
Univ., Canada.
A336 1039.15 Stronger Composite Dental Restoration Results
from Inclusion of Extracellular Matrix Protection Factor-2, a
New Class of Matrix Metalloprotease 8 Inhibitor. D.W. Persky,
N. Tuloglu, H. Ghanta, K. Kitagaito, H. Ciccarelli, G. Clauss,
V. Datillo, A. Selim, F. Ozer, M. D’Angelo. Philadelphia
Col. of Osteo. Med., Osman Gazi Univ., Turkey and Univ.
of Pennsylvania.
A337 1039.16 Determination of Palatal Bone Density to Aid
in Oral Mini-implant Surgical Success. A. Flores, J.C. Reed.
Grand Valley State Univ.
A338 1039.17 Secondary Chondrogenesis on the Coronoid
Process of the Mandible Requires Both FGF and TGFβ
Signaling. K.C. Woronowicz, D.Z. Jaul, S.T. Herfat, A.J.
Fields, J.C. Lotz, R.A. Schneider. UCSF.
1040.ANATOMY
Poster
Exhibit Halls A-D
A339 1040.1 The Birth and Evolution of Modern Anatomy.
C. Barbieri, C. Lugar, G. Nusse, O. Summers. San Francisco
State Univ.
A340 1040.2 A Medium-Sized, Enlarged Anatomical Model
of Human Ear in Plaster (First Middle of the 20th Century) P.P.
Le Floch-Prigent, V. Fromager, J-B. Gillot. Versailles-Saint
Quentin Univ., France.
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A341 1040.3 A Very Large-Sized Enlarged Anatomical Model
of Human Ear in Plaster (First Middle of the 20th Century) P.P.
Le Floch-Prigent, M. Fromanger, J-B. Gillot. Versailles-St.
Quentin Univ. and Librairie Alain Brieux, Paris.
A342 1040.4 An Enlarged Anatomical Model of Ear in Wax
(Tramond, Paris), Late 19th Century. P.P. Le Floch-Prigent,
M. Fromanger, J-B. Gillot, S. Verdeille. Versailles-St. Quentin
Univ. and Librairie Alain Brieux, Paris and CIMOP.
A343 1040.5 Does Sinus Surgery Increase the Risk of Orbital
Fractures in Patients? R. Joshi, M. Johnson, K. Willmore, K.
Galil, T. Jenkyn, L. Sowerby, C. Moore. Western Univ. and St.
Joseph’s Hosp., London, Canada.
A344 1040.6 Dissection of a New Born: A Visceral Model in
Wax by C. Kellner, Early 20th Century. P.P. Le Floch-Prigent,
M. Fromanger, J-B. Gillot, P. Barbet. Versailles-Saint Quentin
Univ., Librairie Sci. Brieux, Paris and Descartes Univ., France.
A345 1040.7 A Sample of the Tabulae Sceleti et Musculorum
Corporis Humani by Albinus and Wandelaar, Leyden, 1747 P.P.
Le Floch-Prigent, M. Fromanger, J-B. Gillot. Versailles-Saint
Quentin Univ. and Librairie Sci. Brieux, Paris.
A346 1040.8 An Original Letter of Georges Cuvier to
Charles Bell: 1832, January 24th about the Models of Anatomy
in “Papier Mâché” by the Dr. Auzoux. P.P. Le Floch-Prigent,
M. Fromanger, J-B. Gillot. Versailles-Saint Quentin Univ. and
Librairie Sci. Brieux, Paris.
A347 1040.9 Gautier d’Agoty, 1746, Paris: A Coloured Plate
of Six Dissections of the Upper Limb. P.P. Le Floch-Prigent,
M. Fromanger, J-B. Gillot. Versailles-Saint Quentin Univ. and
Librairie Sci. Brieux, Paris.
A348 1040.10 Laterality of Pancreatic Metastases from
Renal Cell Carcinoma: An Anatomical Perspective from
the Left Kidney and Tail of the Pancreas. A.J. Raffoul, C.K.
Hartley, M. Johnson, J.A. Gomez, S. Pautler, V. McAlister.
Western Univ., London Hlth. Sci. Ctr. and St. Joseph’s Hosp.,
London, Canada.
A349 1040.11 Ultrastructural Changes and Nestin Expression
Accompanying Compensatory Renal Growth after Unilateral
Nephrectomy in Adult Rats. M.A. Eladl, M. El-Sherbiny, W.M.
Elsaed, H. Atef, M. Guimei. Univ. of Sharjah, United Arab
Emirates, Univ. of Mansoura, Egypt, and ALMaarefa Col.,
Saudi Arabia.
A350 1040.12 Laterality and Locality of Metastatic Renal
Cell Carcinoma to Pancreatic Position: Right Kidney RCC
Mechanism of Dissemination to Pancreatic Position. C.K.
Hartley, A. Raffoul, M. Johnson, J.A. Gomez, S. Pautler, V.
McAlister. Western Univ., Univ. Hosp. London and St. Josephs
Hosp., London, Canada.
A351 1040.13 Marked Individual Differences in the Propensity
to Select Methamphetamine Over Food Reinforcement in a Rat
Preclinical Model. M. Purpura. Univ. California Santa Barbara.
1041.ANATOMY: ANIMAL MODELS
Poster
Exhibit Halls A-D
A352 1041.1 An Animal Series of Embryological Models
in Plaster by Meusel in Germany, Circa 1900, Probably
Representing the Amphioxus. P.P. Le Floch-Prigent.
Versailles-Saint Quentin Univ., France.
346
A353 1041.2 is Diabetic Glomerular Basement Membrane
Thickening Hyperglycemia Driven or Is It a Part of the Normal
Aging Process? E. Carlson, J. Bleth, C. Miller, D. Laturnus,
L.K. Young, E. Schaff. Univ. of North Dakota.
A354 1041.3 Pig (Sus suis): A Half-Sized, Dismantabled,
“Ecorché” Anatomical Model of the First Part of the 20th
Century. P.P. LE FLOCH-PRIGENT, J-B. GILLOT. VersaillesSaint Quentin Univ. and Librairie Sci. Brieux, Paris.
A355 1041.4 The Lumbar Facet Joint Capsule Thickens
following
Spinal
Segmental
Hypomobility-Induced
Osteoarthritis. A.N. Benckendorf, J.A. Merlo, G.D. Cramer,
J.W. Little. Saint Louis Univ. Sch. of Med. and Doisy Col. of
Hlth. Sci. and Natl. Univ. of Hlth. Sci., Lombard, IL.
A356 1041.5 Lumbar Spinal Segmental HypomobilityInduced Osteoarthritis Is Associated with Early Regression of
Facet Joint Synovial Folds. J.A. McDowell, J.A. Merlo, G.D.
Cramer, J.W. Little. Saint Louis Univ. Sch. of Med. and Doisy
Col. of Hlth. Sci. and Natl. Univ. of Hlth. Sci., Lombard, IL.
1042.ANATOMY: RESPIRATORY
Poster
Exhibit Halls A-D
A357 1042.1 Respiratory Complications with Coincident
Kyphoscoliosis and Type Iv Hiatal Hernia. D. Hutchinson, S.
Worku. Ross Univ. Sch. of Med.
A358 1042.2 Post-pneumonectomy Compensatory Lung
Growth Is Associated with Spatially Dependent Blood-Borne
Myofibroblast Recruitment. A. Ysasi, B. Gibney, K. Chamoto,
C. Valenzuela, R. Bennett, W. Wagner, M. Ackermann, A.
Tsuda, S. Mentzer. Brigham and Women’s Hosp., Harvard
Med. Sch., Johannes Gutenberg Univ., Mainz and Harvard
Sch. of Publ. Hlth.
1043.ANATOMY: MUSCULOSKELETAL
Poster
Exhibit Halls A-D
A359 1043.1 Review of Anatomical Changes in the
Musculature of the Foot as Seen in the Cadavers Study with
Hallux Valgus. P-W. Kim. Indiana Wesleyan Univ. Sch. of
Hlth. Sci.
A360 1043.2 The Morphological and Biomechanical
Characteristics of the Ligamentum Mucosum and Its Potential
Role in Anterior Knee Pain. M.E. Norris, T. Burkhart, M.
Johnson, M. Sandig,T. Smallman, A. Getgood. Western Univ.,
Canada and Melbourne Orthopaed. Gp., Windsor, Australia.
A361 1043.3 An Expansion of the Anatomy of the
Anterolateral Ligament of the Knee: Morphological Variation
and an Alternate Dissection Approach. M.F. Parker, H.F. Smith.
Arizona Col. of Osteo. Med., Midwestern Univ. and Arizona
State Univ. Sch. of Human Evol. and Social Change.
TUESDAYANATOMY
A362 1043.4 Hindlimb Anatomy of Three Anole Lizards:
Anolis equestris, A. frenatus and A. Biporcatus L.E. Johnson,
J. Robertson, B. Garns, S. Gilpin, M. Jordan, M. Elkins, K.
Kusumi, R. Fisher. Univ. of Arizona Col. of Med., Phoenix and
Arizona State Univ. Sch. of Life Sci., Tempe.
A363 1043.5 Expression of Myostatin in Postnatal Mouse
Head and Leg Muscles. Y. Miwa, H. Takada, I. Sato, M.
Sunohara. The Nippon Dent. Univ.
A364 1043.6 Cadaveric Study of the Anatomical and
Histological Relationships between the Achilles and Plantaris
Tendons. J. Goral, S.E. Inouye, Z. Belford, E. Leland, B.
Ferrel, A. Cheung, A. Meyer, N. Fanter. Midwestern Univ.,
Chicago Col. of Osteo. Med. and Edward Hines Jr. VA Hosp., IL.
A365 1043.7 Cadaveric
Study
of Anatomical
and
Histological Characteristics of Flexor Hallucis Longus Tendon
at Possible Sites of Tendon Rupture. J. Goral, S.E. Inouye, B.
Ferrel, A. Cheung, Z. Belford, E. Leland, A. Meyer, N. Fanter.
Midwestern Univ., Chicago Col. of Osteo. Med. and Edward
Hines Jr. VA Hosp., IL.
A366 1043.8 Using Ultrasound to Prevent Iatrogenic Injury
to the Dorsomedial Cutaneous Nerve of the Hallux. K.D. Miller,
J.V. Swearingen, M.J. Zdilla, H.W. Lambert. West Virginia
Univ. Sch. of Med. and West Liberty Univ.
A367 1043.9 Mapping the Intersection Point of the
Dorsomedial Cutaneous Nerve of the Hallux and the Extensor
Hallucis Longus Tendon to Prevent Iatrogenic Injury during
Foot Operative Procedures. K.D. Miller, J.V. Swearingen, D.T.
Burns, M.J. Zdilla, H.W. Lambert. West Virginia Univ. Sch. of
Med. and West Liberty Univ.
A368 1043.10 Long-Term Muscle Involvement after Neonatal
Pain. J.A. Alves, A.L.B. Simões, F.J. Dias, E.C. Carmo, N.B.
Machado, L.S. Sanada, V.P.S. Fazan. Sch. of Med. of Ribeirão
Preto, Brazil.
A369 1043.11 The Presence of a Variant Leg Muscle,
Flexor Digitorum Accessorius Longus, Causing Tarsal Tunnel
Syndrome, or Posterior Tibial Neuralgia. J.V. Swearingen, P.M.
Kennedy, K.P. Whipp, K.D. Miller, M.J. Zdilla, H.W. Lambert.
West Virginia Univ. Sch. of Med. and West Liberty Univ.
A370 1043.12 The Anatomy of Pediatric Laparoscopic and
Thoracoscopic Procedures – Newer Concepts and Procedures.
T. Ghosh. ndian Inst. of Morphol., Kolkata.
1044.ANATOMY: GASTROINTESTINAL
Poster
Exhibit Halls A-D
A371 1044.1 Japanese Herbal Medicine, Juzentaihoto,
Suppress the Lymphocyte Infiltration in the Aging Mouse
Salivary Glands. N. Nonaka, M. Nakamura. Showa
Univ., Japan.
A372 1044.2 Accessory Quadrate of Liver and Its
Implications. C. Chandrasekaran. So. Med. Univ., China.
A373 1044.3 Maternal High Fat Diet Alters Expression
of Myenteric Ganglia and Glia Prior to the Development of
Obesity. C.A. McMenamin, K. Browning. Penn State Col.
of Med.
A374 1044.4 Human Hepatic Progenitor Cells in Hepatic
Fibrosis of Elderly Cadavers: Lobular Distribution of Cytokeratin
7 and 19 Expressing Hepatic Progenitor Cells. C.Y.M. Png,
K.M. Mark. Icahn Sch. of Med. at Mount Sinai.
A375 1044.5 Human Hepatic Progenitor Cells in Hepatic
Fibrosis of Elderly Cadavers: Cytokeratin 7 Marks Intermediate
Hepatocyte-Like Cells. K.M. Mak, C.Y.M. Png. Icahn Sch. of
Med. at Mount Sinai.
A376 1044.6 You Are What You Eat or You Eat What You
Are? Comparative Mammalian Gastrointestinal Anatomy.
B.J. Ramalanjaona, C. Sorrento, A.S. Pagano, S. Marquez.
SUNY Downstate Med. Ctr. and NYU Sch. of Med.
A377 1044.7 The Development of the Hepatic Venous
System in Man. J. Hikspoors, M. Peeters, H. Mekonen, G.
Mommen, E. Köhler,W. Lamers. Maastricht Univ., Netherlands.
1045.ANATOMY: UROGENITAL
Poster
Exhibit Halls A-D
A378 1045.1 Computer-Assisted Anatomical Dissection of
the Renal Plexus to Refine Renal Denervation in the Treatment
of Refractory Hypertension. T. Bessede, C. Lebacle, K.
Nyangoh Timoh, J. Martinovic, D. Diallo, M. Zaitouna, G.
Benoit. Paris Sud Univ., Le Kremlin Bicetre, Paris Sud Univ.
Hosp. of Bicetre and Hosp. Antoine Beclere, Clamart, France.
A379 1045.2 Uro-genital Development in Juvenile SpragueDawley Rats: A Histomorphologic and Immunohistochemical
Study. V. Vrolyk, A. Apreutese, C. Gordon, R. Forster, A.
Graham, B. Palate, J. Haruna, M-O. Benoit-Biancamano.
Fac. of Vet. Med., Univ. of Montreal, St.-Hyacinthe, CiToxLAB,
Laval and CiToxLAB France, Evreux.
A380 1045.3 Innervation of the Female Levator Ani Muscle
and Consequences in Pelvic Floor Dysfunctions. T. Bessede,
K. Nyangoh Timoh, C. Lebacle, J. Martinovic, M. Zaitouna, D.
Diallo, M. Creze, G. Benoit, D. Moszkowicz. Paris Sud Univ.,
Hosp. of Bicetre and Hosp. Antoine Beclere, Clamart, France.
A381 1045.4 The Anatomy of the Human Myometrium:
A Stereological Approach. P. Dockery, E.M. Sweeney, C.J.
Denis, M.J. John. Anat. Sch. of Med. NUIGalway, Ireland and
A382 1045.5 Standardization of Nodal Counting in the
Obturator Fossa of Cadaveric Specimens. T.S. Beveridge, M.
Johnson, N. Power, B.L. Allman. Schulich Sch. of Med. and
Dent., Western Univ. and London Hlth. Sci. Ctr., Canada.
A383 1045.6 Optical Clearing and 3D-Histology of Murine
Testis. J.A. Kaufman, M.J. Castro, J.R. Rodriguez-Sosa.
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1046.ANATOMY: FORM AND VARIATION
Poster
Exhibit Halls A-D
A384 1046.1 The Branching and Innervation Pattern of the
Radial Nerve in the Forearm: A Study to Clarify the Literature.
F.K. Sawyer, R. Lufler. Tufts Univ. Sch. of Med.
A385 1046.2 3D Modeling of Geometric Structure and
Tissue Composition of Human Laryngeal Anatomy via HighResolution MRI Segmentation and Histological Analysis. N.L.
Mason, H. Wang, B. Heldt, B. Long, A. Nazaran, R. Reid,
N.K. Bangerter, J.J. Wisco. California Northstate Univ. Col. of
Med., Brigham Young Univ. and Univ. of Utah Sch. of Med.
A386 1046.3 Studies of Bilateral Asymmetry of the Upper
Limb in Adult Males in Ilorin Metropolis, Nigeria. A.O. Oyewopo,
I. Gbadamosi, L. Ezra, T. Arogundade, R. Jaji-Sulaimon.
Univ. of Ilorin, Nigeria.
A387 1046.4 Nerve-Muscle Perforation Variations in
the Upper Limb: A Review with a Description of Three New
Variants. J.M.A. Miller, R. Trelease. UCLA David Geffen Sch.
of Med.
A388 1046.5 Prevalence of Pathology in the Cadaveric
Heart, Lungs, Liver and Kidneys. M. Pontiff, G. Rae. LSU Hlth.
Sci. Ctr., New Orleans.
A389 1046.6 Peno-Scrotal Raphe Absence and Its
Herniation. K.D. Dokiparty. So. Med. Univ., China.
A390 1046.7 A Rare Case of Bilateral Supra-Piriformis Pelvic
Exit of the Common Fibular Nerve and Its Clinical Relevance.
C. Vasan, E. Goldman, N. Vasan. Cooper Med. Sch. of Rowan
Univ., NJ.
A391 1046.8 Accessory Slip of Latissimus Dorsi. H.M.
Beyea, M.I. Hurley, M.P. Olivieri, T. Stevens. D’Youville
Col., NY.
348
A392 1046.9 The Facial Nerve: The Path of Its Branches to
the Muscles of the Infraorbital Region That Lift the Upper Lip
in Relation to the Deep Fascia of the Midface. C. Andretto
Amodeo, V. Delmas, A. Casasco, G.S. Keller. Casa di Cura
La Madonnina, Milan, Univ. Paris Descartes, Univ. of Pavia and
David Geffen Sch. of Med., UCLA.
A393 1046.10 Hemorrhage Secondary to Interforamina
Implant Surgery: Anatomical Considerations. P. Gill, K.
Willmore, T. Wilson, H. Perinpanayagam, K. Galil. Western
Univ., Canada.
A394 1046.11 Case Report of a Bilateral Absence of the
Semimembranosus Muscle. N. Morrison, S. Hervey, J.
Runyeon. Univ. of Oregon.
A395 1046.12 Anatomical Variation and Morphological
Relationships of the Human Pharyngeal Recess: Clinical
Implications. C.M. Sorrento, B. Ramalanjaona, A. Pagano,
W. Lawson, S. Márquez. SUNY Downstate Med. Ctr., NYU
Sch. of Med., Langone Med. Ctr. and Icahn Sch. of Med. at
Mount Sinai.
A396 1046.13 Prevalence of the Anterolateral Ligament. J.
Hinkley, P. Lampert, C. Canby. Des Moines Univ.
A397 1046.14 Clinical Implications and Embryological
Explanation for Unilateral Variation in Formation of Sciatic
Nerve in Relation to Piriformis Muscle – A Case Report.
A.R,J. Nayakanti, K.R. Srinivasan, S.D. Velichety. Vinayaka
Missions Univ. and Med. Ctr., Salem, India, Avalon Univ. Sch.
of Med., Netherlands Antilles and Sri Padmavathi Med. Col.
and Hosp., Tirupati, India.
A398 1046.15 The Relationship between the Parotid Fascia
and the Deep Fascia of the Infraorbital Region: A New Concept
in Descriptive and Applied Anatomy. C. Andretto Amodeo, V.
Delmas, A. Casasco, G.S. Keller. Casa di Cura La Madonnina,
Milan, Univ. Paris Descartes, Univ. of Pavia and David Geffen
Sch. of Med., UCLA.
A399 1046.16 Subcutaneous Tissue Depth over Intraosseous
Infusion Sites in a Cadaveric Model. M. Glazier, J.C. Reed.
Grand Valley State Univ.
A400 1046.17 Pelvic Incidence in Children and Adolescents
Predicts Mature Lumbar Lordosis. J.F. Bailey, S. Shefi, M.
Soudack, P.A. Kramer, E. Been. Univ. of Washington, UCSF
and Ono Acad. Col., Edmond and Lily Safra Children’s Hosp.,
Tel Hashomer and Tel Aviv Univ.
TUESDAYBIOCHEMISTRY
1047.DOUBLE-STRAND BREAK AND REPAIR
1050.STRUCTURAL INSIGHTS INTO DNA REPAIR
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C1
1047.1 Multiple Alternative End-Joining Mechanisms
Exhibit Varying Dynamics in Double Strand Break Repair. M.L.
Woods, A. Lewis, C. Barnes. University Col. London.
C2
1047.2 Olive Leaf Metabolites as Covalent Human
Topoisomerase II Poisons. K.R. Vann, C.A. Sedgeman, J.
Gopas, A. Golan-Goldhirsh, N. Osheroff. Vanderbilt Univ.
Sch. of Med., Ben-Gurion Univ. of Negev, Soroka Univ. Med.
Ctr., Beer Sheva, Ben-Gurion Univ. of Negev (Sede Boqer
Campus) and VA Tennessee Valley Healthcare Syst.
1048.FANCONI ANEMIA
C8
1050.1 Crystal Structure of the Cancer Genomic
DNA Mutator APOBEC3B Catalytic Domain. H. Aihara, K.
Shi, M.A. Carpenter, K. Kurahashi, R.S. Harris. Univ. of
C9
1050.2 Chemical and Biochemical Stability of Guanine
Lysine Crosslinks Formed by Guanine Oxidation. D. Esparza,
J. Mincitar, N. Tran, A. Ramos, K. Miller, E. Stemp. Mount
Saint Mary’s Univ.
1051.TELOMERES AND TELOMERASE
Poster
Poster
Exhibit Halls A-D
C3
1048.1 A Nucleolar Role for the Fanconi Anemia
Pathway Protein, FANCI, in rDNA Transcription. S.B. Sondalle,
S. Longerich, P. Sung, S.J. Baserga. Yale Univ.
1049.REPAIR DURING DNA REPLICATION
Poster
Exhibit Halls A-D
C4
1049.1 Mitochondrial DNA Damage Persistence Due
to DNA Polymerase Gamma Disease Mutations. R. Krasich,
W.C. Copeland. NIEHS, NIH, Research Triangle Park.
C5
1049.2 A Genome Wide Screen to Identify Genes That
Prevent the Accumulation of Mutations. H.W. Hombauer, T.
Schmidt, G.X. Reyes Cava, U. Ceylan, K. Gries, M. Meurer,
M. Knop. DKFZ and Univ. of Heidelberg, Germany.
C6
1049.3 Participation of Distal RRRY Motif in Strand
Displacement DNA Synthesis by A-Family DNA Polymerases.
M.J. Modak, A. Ketkar, K. Singh. Rutgers Univ., Newark, Univ.
of Arkansas for Med. Sci. and Univ. of Missouri-Columbia.
C7
1049.4 Rad18 Regulates BRCA2, FANCD2, and
Rad51 to Repair Topoisomerase 1 Inhibitor-Induced DNA
Lesions through Homologous Recombination. K. Palle, K.
Tripathi, D.W. Clark, C. Mani. USA Mitchell Cancer Inst.,
Mobile, AL.
Exhibit Halls A-D
C10 1051.1 Transcription by the Telomeric Shelterin
Protein TRF2 Is Telomere-Length Dependent – Telomeric
Partitioning and Global Transcription. S. Chowdhury. CSIR
Inst. of Genomics and Integrat. Biol., New Delhi.
C11
1051.2 The Roles of Telomerase in Regeneration
during Aging and the Telomeric DNA Sequence Identification in
Aeolosoma viride C.F. Chen. Natl. Taiwan Univ.
C12 1051.3 Quantification of Telomerase Activity in
Colonial Ascidians. M. Durham, C. Beck, E. Keeling. Cal Poly
State Univ., San Luis Obispo.
C13 1051.4 TERT Promoter Mutations and Cancer. R.
Nwumeh, J. Stern, T.R. Cech. Univ. of Colorado Boulder and
Washington Univ. in St. Louis.
C14 1051.5 Expression and Assembly of Active Human
Telomerase in Escherichia coli J.L. Hansen, T. Thiyagarajan,
A.K. Larson, A. Rideout, D.T. Hansen. A.T. Still Univ., Barrow
Neurol. Inst., Phoenix and Med. Univ. of South Carolina.
C15 1051.6 Sphingosine
Kinase-2/Sphingosine
1-Phosphate Signaling Regulates Telomere Dysfunction
through GADD45 and TCF21 Mediated Tumor Suppressor
Mechanisms in Lung Cancer. S. Panneer Selvam, E. GarrettMayer, C.D. Smith, B. Ogretmen. Med. Univ. of South Carolina.
1052.TRANSLESION AND ERROR-PRONE
DNA POLYMERASES
Poster
Exhibit Halls A-D
C16 1052.1 Human Y-Family DNA Polymerase Kappa Is
More Tolerant of Amino Acid Substitutions in the Active Site
Loop Region Than Its E. coli Ortholog Dinb. N.M. Antczak, P.
Ippoliti, J. Walsh, M. Packer, P. Beuning. Northeastern Univ.
349
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C17 1052.2 Specificity and Activity of DNA Polymerase
DinB and Polκ Loop Swap Variants. M.R. Packer, N. Antczak,
P. Beuning. Campbell Univ. and Northeastern Univ.
C18 1052.3 Investigation of Structure-Activity Relationships
for Small-Molecule Inhibitors of Human DNA Polymerase Eta.
M.K. Zafar, L. Maddukuri, S. Eddy, A. Ketkar, N.R. Penthala,
P.A. Crooks, R.L. Eoff. Univ. of Arkansas for Med. Sci.
C19 1052.4 Biochemical and Biological Investigation of
Human Polymerase Kappa Activity on G-Quadruplex DNA. S.
Eddy, L. Maddukuri, M. Tillman, R. Smith, A. Ketkar, M.K.
Zafar, R.L. Eoff. Univ. of Arkansas for Med. Sci.
C20 1052.5 Aberrant Activation of the Kynurenine Pathway
in Gliomas Increases Polymerase Kappa Expression and
Promotes Genomic Instability and Chemoresistance. A.
Bostian, L. Maddukuri, M. Reed, T. Savenka, J. Hartman, L.
Davis, D. Pouncey, G. Miller, R. Eoff. Univ. of Arkansas for
Med. Sci.
C21 1052.6 Identifying
Y-Family
DNA
Polymerase
Inhibitors to Improve Anti-Cancer Drugs L. Maddukuri, M.K.
Zafar, N. Penthala, P.A. Crooks, R.L. Eoff. Univ. of Arkansas
for Med. Sci.
C22 1052.7 Investigating the Mechanism of Trans-lesion
Synthesis by Human DNA Polymerase Kappa. Z.W. Younger,
T. Allen, B. Sampoli Benitez. Marymount Manhattan Col.
C23 1052.8 In Silico Exploration of the Mechanism of
Translesion Synthesis by DinB. E. Perez, B. Sampoli Benitez.
Marymount Manhattan Col.
1053.CHROMATIN REMODELING AND EPIGENETICS
Poster
Exhibit Halls A-D
C24 1053.1 NURF Localizes in Gene Bodies to Regulate
mRNA Processing. J. Landry, A. Alhazmi, M. Mack, A.
Petencin, H. Nelson, J. Hiegel, V. Koparde, N. Scarsdale, C.
Lyons, M. Dozmorov. Virginia Commonwealth Univ.
C25 1053.2 Endocrine Disrupting Chemical, Bisphenol-A,
Induces Breast Cancer Associated Homeobox Containing
Gene HOXB9 Expression In Vitro and In Vivo. P. Deb, A. Bhan,
I. Hussain, K.I. Ansari, S.A. Bobzean, D. Saha, L.I. Perrotti,
S.S. Mandal. Univ. of Texas at Arlington and Univ. of Texas
C26 1053.3 Effect of Inflammatory Cytokines on DNA
Methylation and Demethylation. J. Winfield, A. Esbitt, S.F.
Seutter, B. Desai, M. Abdo, M. Vasconez, W. Laidlaw, K.
Green, S.M. Shamseddin, R.C. Borghaei. Philadelphia Col. of
Osteo Med., Temple Univ. Kornberg Sch. of Med. and Kennett
Square, PA.
C27 1053.4 Implications for 4-Oxo-2-Nonenal-Derived
Histone Adducts in Mediating Gene Expression. J.M.
Camarillo, J.J. Galligan, L.J. Marnett. Vanderbilt Univ.
C28 1053.5 Age-Related
Epigenetic
Modifications
Contribute to Dysfunction of Male Germline Progenitor Cells.
T-L. Lee, J. Liao, W-Y. Chan. The Chinese Univ. of Hong Kong.
C29 1053.6 Sphingosine Kinase 2 Generated Nuclear S1P
Is an Epigenetic Co-regulator of Pseudomonas aeruginosaInduced Lung Inflammation. D.L. Ebenezer, P. Fu, E.
Berdyshev, V. Natarajan. Univ. of Illinois at Chicago.
350
C30 1053.7 Methylation Correlates with Suppressed
Expression of Immunomodulatory Genes in the Tumor-Adjacent
Stroma of African American Prostate Cancer Compared
Patients of European American Ancestory. F. Rahmatpanah, Z.
Jia, B. Men, P. Rahmatpanah, S. Madahian, M. McClelland,
D. Mercola. Univ. of California, Irvine.
1054.NON-CODING RNA AND GENE REGULATION
Poster
Exhibit Halls A-D
C31 1054.1 Interactions among rsm ncRNAs and Rsm
RNA-Binding Proteins in the Plant Pathogen Pseudomonas
syringae D. C3000 C.J. Rous, M. Fishman, M.J. Filiatrault.
St. Mary’s Col. of Maryland and Cornell Univ.
C32 1054.2 Regulation of kcnd2 by microRNA-30e in Rat
Trigeminal Ganglions following Chronic Constriction Injury of
Infraorbital Nerve. Y. Dong. Nanjing Stomatol. Hosp., Med.
Sch. of Nanjing Univ., China.
C33 1054.3 Reduced Expression of MicroRNA-200
Family Members Lead to Epithelial-Mesenchymal Transition
of a Chemoresistant Colorectal Cancer Cell Line. K. San, A.
Martino, U. Ezekiel. Sch. of Med., Saint Louis Univ.
C34 1054.4 The Critical Role of MAF1 in Repression of
RNA Polymerase III Impacts Metabolic Efficiency in Mice.
I.M. Willis, N. Bonhoure, R.D. Moir, A. Byrnes, W. Hodroj,
V. Praz, F. Preitner, G. Marcelin, S. Chua;Jr., N. MartinezLopez, R. Singh, J. Auwerx, G. Willemin, H. Shah, K. Hartil,
B. Vaitheesvaran, I. Kurland, N. Hernandez. Albert Einstein
Col. of Med., Univ. of Lausanne and Fed. Polytech Sch. of
Lausanne (EPFL)
C35 1054.5 Transfer RNA Fragments: A Novel Class of
Non-micro Short RNAs That Uses Ago1, 3 and 4 to Repress
Specific Target RNAs through 5’ Seed Sequences. A. Dutta, P.
Kumar, M. Kiran, C. Kuscu. Univ. of Virginia.
C36 1054.6 A Specialized Mechanism of MicroRNAMediated Translation in Quiescence. S. Vasudevan, S.I.A.
Bukhari, S.S. Truesdell, S. Lee, S. Kollu, A. Classon, M.
Boukhali, E. Jain, A. Yanagiya, R. Sadyrev, W. Haas. MGHHarvard Med. Sch. and McGill Univ.
C37 1054.7 ACA11, a Small Nucleolar RNA Activated in
Multiple Myeloma, Stimulates Proliferation by Inactivating
NRF2 and Increasing Redox Signaling. N. Mahajan, J.D.
Weber, L.B. Maggi, M.H. Tomasson. Washington Univ. in
St Louis.
C38 1054.8 Characterizing the Functional Roles of miR1017 M. de Cruz, A. Flynt. Univ. of So. Mississippi.
1055.TRANSCRIPTIONAL REGULATION
Poster
Exhibit Halls A-D
C39 1055.1 DNA Distortions Imposed by the Transcriptional
Regulator PecS from Pectobacterium atrosepticum Are
Attenuated on Protein Oxidation. D.K. Deochand, A. Grove.
LSU, Baton Rouge.
TUESDAYBIOCHEMISTRY
C40 1055.2 The Role of the Actin-Binding Protein, Alpha
Actinin 4, in Transcriptional Regulation by Glucocorticoid
Receptors in Glomerular Podocytes. X. Zhao, S. Khurana, L.
Bruggeman, H-y. Kao. Case Western Reserve Univ.
C41 1055.3 Transcriptional and Translational Regulation of
CCAAT/Enhancer Binding Protein β Expression by. P53 B. Hu,
Z. Wu, D. Bai, S. Sheng, S.H. Phan. Univ. of Michigan.
C42 1055.4 Functional Role of UPF2 Phosphorylated
Regions in Translation Termination in Yeast. L.A. Haddock III,
E.M. Colón-Morales, C. Lasalde, Q. Lin, C.I. González. Univ.
of Puerto Rico, Rio Piedras Campus, Univ. of Puerto Rico at
Bayamón, Univ. at Albany, SUNY and UPR-Med. Sci. Campus,
San Juan.
C43 1055.5 CTEN Is a Novel ΔNp63α Target for the
Regulation of Prostate Cell Adhesion and Is Associated
with Prostate Cancer Progression. Y-C. Liao, W-M. Wu, K.
Yang, Y-C. Chen, S.H. Lo. Natl. Taiwan Univ. and Univ. of
California, Davis.
C44 1055.6 Systematic Studies of Effects of the
Discriminator on Stabilization of the Open Complex and
Abortive and Productive Initiation. L. Felth, C. Molzahn, S.
Wang, K. Henderson, E. Ruff, M. Poulos, M. Chhabra, L.
Bieter, I. Artsimovitch, M.T. Record; Jr. Univ. of WisconsinMadison and The Ohio State Univ.
C45 1055.7 Characterization of Marr Family Transcriptional
Regulator (BTH_i0021) from Burkholderia thailandensis A.
Sabrin, A. Gupta, A. Grove. LSU, Baton Rouge.
C46 1055.8 Tumor Suppressor Phosphatase PHLPP
Regulates Gene Expression through Suppression of
Transcription Factor Activation. K. Cohen Katsenelson, J.D.
Stender, C. Glass, A.C. Newton. UCSD.
C47 1055.9 Biochemical
Characterization
of
ZincResponsive Transcription Factors Zur and ZntR in Klebsiella
oxytoca K. Crawford. Midwestern Univ., AZ.
C48 1055.10 The Role of the Nucleoid-Associated Protein
HU in E. coli Transcription. S. Bugliosi, E. Jessen, R. Landick.
C49 1055.11 Regulation of RAP1A and RAP1B by Estrogen
in Human Breast and Ovarian Cancer Cell Lines. N. Elder.
Univ. of St Thomas, MN.
C50 1055.12 Expression Analysis and Characterization
of Tetratricopeptide Repeat Doman 39c (Ttc39c) in Skeletal
Muscle. D. Waddell, J. Menke. Univ. of North Florida.
C51 1055.13 Untethering Glucocorticoid Receptor-Mediated
Transcriptional Repression. E.R. Weikum, W. Hudson, E.
Ortlund. Emory Univ.
C52 1055.14 Characterization and Expression Analysis
of Zinc Finger Protein 593 in Skeletal Muscle. H. Orsech, D.
Waddell. Univ. of North Florida.
C53 1055.15 Characterization of Mn(II) Homeostasis within
Bacillus subtilis M. Baertlein, C. Vos, W. Jeffries, E. Isaacson,
S. Gabriel. Viterbo Univ. and Med. Col. of Wisconsin.
C54 1055.16 Testing for Combinatorial Activity of 5′ and 3′
MyoD Binding Regions in Mouse Acta1 Gene Expression. S.
Esaian, C.M. Gonsalez, H. Vu, G. DeSalvo, J. Morales, G.
Manjurr, B. Wold, S. Sharp. Cal State LA and Caltech.
C55 1055.17 The RexA Protein of λ Phage: A New Member
of a Classic Genetic Switch. C. Schiltz, L. Thomason, C.
Hosford, V. Johnson, H. Pan, D. Court, J. Chappie. Cornell
Univ. and Frederick Natl. Lab. for Cancer Res., MD.
C56 1055.18 Molecular Genetic Response in Xiphophorus
maculatus Skin upon Exposure to Various Wavebands of Light.
J. Chang, Y. Lu, W. Boswell, M. Boswell, K. Caballero, R.
Walter. Texas State Univ.
C57 1055.19 Structure of the Bacterial Transcription
Termination Factor Rho in Complex with the Regulatory Factor
NusG. M. Lawson, J. Berger. Univ. of California, Berkeley and
Johns Hopkins Med. Inst.
1056.RNA STRUCTURE AND TRANSLATION
Poster
Exhibit Halls A-D
C58 1056.1 Eukaryotic Translation Initiation Factor eIF4G
Utilizes Different Domains to Coordinate with eIF4A, eIF4B
and eIF4E In binding 3’ Cap-Independent Translation Element
of Barley Yellow Dwarf Virus. P. Zhao, D. Goss. Hunter
Col., CUNY.
C59 1056.2 Characterization of Maize Necrotic Streak
Virus mRNA 3’ Cap Independent Translation Enhancers
Binding with Eukaryotic Initiation Factors. Q. Liu, D.J. Goss.
Hunter Col. and Grad. Ctr., CUNY.
C60 1056.3 Ribosomal Frameshifting of Trichomonas
vaginalis Virus 2, 3, and 4 Isolates. L. Ai. Millsaps Col., MS.
C61 1056.4 Most Stable G-Quadruplex Structures Are
Selectively Avoided at the Codon Level. S. Basu, G.M.
Arachchilage, H. Piontkivska. Kent State Univ.
1057.RNA STRUCTURE AND DYNAMICS
Poster
Exhibit Halls A-D
C62 1057.1 Thermodynamic Examination of the U6 RNA
and DNA Constructs. J.A. Hanson. Colorado Col.
C63 1057.2 Characterization of the HIV-1 5′UTR
Dimerization Mechanism. J.L.C. Santos, H. Frank, S.
McCowin, C. Sciandra, S.C. Keane, M.F. Summers. Univ. of
Maryland Baltimore County.
C64 1057.3 2-Aminopurine Is a Reporter for the
Formation of the C&·A+Ÿ Wobble Base Pair in U6 snNA. M.
Grossenbacher. Colorado Col.
C65 1057.4 Ethylene Glycol Linkers in Nucleic Acids. A.M.
Ortega. Colorado Col.
1058.RNA STRUCTURE, FUNCTION,
AND REGULATION
Poster
Exhibit Halls A-D
C66 1058.1 Molecular Characterization of Two Human
Lens Epithelial Cell Lines and Their Suitability to Study Function
of Cataract Genes. J. Barton, A.D. Siddam, D. Anand, S.
Lachke. Univ. of Delaware.
351
T
U
E
BIOCHEMISTRYTUESDAY
1059.NUCLEAR ARCHITECTURE AND
CHROMATIN ORGANIZATION
Poster
Exhibit Halls A-D
C67 1059.1 An Old Dog’s New Tricks: iMMP-3 Processes
Nuclear Matrix and Converts Heterochromatin Proteins
Leading to Transcriptional Promotion of HSP Genes. T.
Eguchi, A. Mino, B.J. Lang, S.K. Calderwood. Beth Israel
Deaconess Med. Ctr., Harvard Med. Sch., Natl. Inst. for Geriat.
and Gerontol, Obu-shi, Japan and Joslin Diabetes Ctr., Boston.
1060.RNA-BASED GENE REGULATION
Poster
Exhibit Halls A-D
C68 1060.1 The JAK-STAT Pathway Is Regulated by
miRNA Mediated Ribosomal Frameshifting. J.D. Dinman,
Y.A. Khan, V.M. Advani, Z.R. Flickenger. Univ. of Maryland
College Park.
C69 1060.2 MicroRNA miR-1207-5p-Repression of ATRA
Receptors Determine Retinoid-Resistance in Breast Cancer.
G. Chaudhuri, S. Misra. Meharry Med. Col.
C70 1060.3 Exploration of the Role of the CCR4-NOT
Deadenylase Complex Subunit Regena/NOT2 in MicroRNAMediated Gene Silencing. J. Knox, K. Rees, T. Zbornik, M.
Morin, S. Bowden. Linfield Col., OR.
1061.SMALL RNAS
Poster
Exhibit Halls A-D
C71 1061.1 Effect of 5-Azacytidine on MicroRNA Levels in
the HL-60 Cell Line. M. Gillard, N. Stafford, K. Militello, R.W.
O’Donnell. SUNY Geneseo.
1062.AUTOPHAGY
Poster
Exhibit Halls A-D
C72 1062.1 Autophagy Controls Exosomal Release of
Prions and Lateral Prion Infection. B.A. Abdulrahman, D.H.
Abdelaziz, S. Nishikawa, H. Schatzl. Univ. of Calgary, Canada.
C73 1062.2 Pro-Inflammatory
Cytokines
Induce
Mesenchymal Stem Cell Secretory Phenotype by Increasing
Autophagosomes and Lysosomes. Y-C. Hsueh, H-L. Chen,
T-C. Chang, K.K-Y. Wu. China Med. Univ., Natl. Hlth. Res.
Insts., Zhunan and Natl. Tsing-hua Univ., Taiwan.
352
C74 1062.3 Depletion of BMI1 Induces AutophagyMediated Necroptosis. A. Dey, S. Banerjee, S. Saha, S.
Dwivedi, P. Mukherjee, R. Bhattacharya. Univ. of Oklahoma
Hlth. Sci. Ctr.
C75 1062.4 PGC-1alpha a Novel Regulator of Autophagy.
G. Salazar, J. Huang, Y. Zhao. Florida State Univ.
C76 1062.5 Antitumor DNA-Damaging C-1748 Is a
New Inhibitor of Autophagy That Triggers Apoptosis in
Human Pancreatic Cancer Cell Lines. B. Borowa-Mazgaj,
A. Skwarska, E. Augustin, A. Radomińska-Pandya, Z.
Mazerska. Gda?sk Univ. of Technol. and Univ. of Arkansas for
Med. Sci.
C77 1062.6 Conformational Flexibility Enables Function
of a BECN1 Region Essential for Starvation-Mediated
Autophagy. S. Sinha, Y. Mei, A. Ramanathan, K. Glover, Z.
Yang, C. Colbert. North Dakota State Univ. and Oak Ridge
Natl. Lab., TN.
C78 1062.7 GSK3β Modulates Excess Nutrient-Induced
Autophagy Impairment in Human Aortic Endothelial Cells via
FOX. O1 K. Weikel, N. Ruderman, Y. Ido. Boston Univ. Sch.
of Med.
C79 1062.8 IP3 Receptor Determines Increased Basal
Mitochondrial Calcium and Autophagy Regulation in Mdx
Skeletal Muscle. D. Valladares, Y. Utreras-Mendoza, C.
Morales, C. Campos, F. Westermeier, S. Lavandero, E.
Jaimovich. Univ. of Chile.
C80 1062.9 ULK1-Mediated Autophagy Is Required for
Skeletal Muscle Recovery from Acute Ischemia-Reperfusion
Injury. R.J. Wilson, J.C. Drake, M. Zhang, Z. Yan. Univ.
of Virginia.
1063.NEW FRONTIERS IN PROTEIN
QUALITY CONTROL
Poster
Exhibit Halls A-D
C81 1063.1 Role of the CHIP/Hsp70 Protein Quality Control
Complex as an Information Processor. R.C. Page. Miami Univ.
C82 1063.2 The
Degradation
Requirements
for
Topologically Distinct Quality Control Substrates in the Yeast
Endoplasmic Reticulum. C.J. Guerriero, K.R. Reutter, A.
Augustine, J.L. Brodsky. Univ. of Pittsburgh.
C83 1063.3 A High-Content RNAi Screen to Elucidate
Novel Effectors of Cardiac Proteotoxicity. P.M. McLendon,
G. Davis, J. Gulick, K. Shay-Winkler, J.D. Molkentin, J.
Robbins. Cincinnati Children’s Hosp. Med. Ctr.
C84 1063.4 Variant-Specific and Reciprocal Hsp40
Functions in Hsp104-Mediated Prion Elimination: A Potential
Role for the Anti-prion J-Protein 1 J.K. Hines, Z.A. Sporn, M.T.
Astor, E. Kamiya. Lafayette Col., PA.
TUESDAYBIOCHEMISTRY
1064.PROTEIN DEGRADATION IN HEALTH
AND DISEASE
1067.STRUCTURE AND ASSEMBLY OF
MOLECULAR COMPLEXES
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C85 1064.1 Cholesterol-Mediated
Degradation
of
7-Dehydrocholesterol Reductase Switches the Balance from
Cholesterol to Vitamin D Synthesis. L.J. Sharpe, A.V. Prabhu,
W. Luu, A.J. Brown. Univ. of New South Wales.
C86 1064.2 An Inherited Developmental Disorder Reveals
Functions for WHAMM and the Actin Nucleation Machinery in
Early Stages of Autophagy. K. Campellone, A. Mathiowetz, A.
Russo, E. Baple, A. Crosby. Univ. of Connecticut and Univ. of
Exeter Med. Sch.
C87 1064.3 The Interplay between S-Palmitoylation
and Gamma-COP Binding of MAN1B1 Manages Alpha-1Antitrypsin Quality Control. E. Young, R.N. Sifers. Baylor Col.
of Med.
1065.REGULATION OF PROTEIN SYNTHESIS
Poster
Exhibit Halls A-D
C88 1065.1 Translational Recoding in Human Disease.
V.M. Advani, R.C. Kobylarz, J.D. Dinman. Univ. of Maryland
College Park.
C89 1065.2 lternative Ribosomes Synthesize Alternative
Proteins. A. Dow, S. Prisic, Univ. of Hawaii.
1066.RIBOSOME AND TRANSLATION
Poster
C95 1067.1 Assembly of Human Translational Elongation
Factor 1B Is Based on the Interaction of the Glutathione
Transferase-Like Domains from Alpha and Gamma Subunits.
Y.S. Choi, H.J. Lee, B.S. Kang. Kyungpook Natl. Univ.,
South Korea.
C96 1067.2 Knockdown of Axonemal Inner Arm Dynein
Protein IC138 Trypanosoma brucei Causes Flagellar
Detachment and Defects in Motility. A. Marchese, C. Wilson,
A.L. Springer. Siena Col., NY.
C97 1067.3 Assessing Species-Specific Determinants of
DNA Binding in McrB Homologs. C.J. Hosford, V.M. Johnson,
J. Chappie. Cornell Univ.
C98 1067.4 The Role of the C1q Domain of Zebrafish
Otolin1a in Otolith Morphogenesis. O. Das. SUNY Downstate
Med. Ctr.
1068.TRNA SYNTHETASES: STRUCTURE,
MECHANISM AND EVOLUTION
Poster
Exhibit Halls A-D
C99 1068.1 Altering the Enantioselectivity of Tyrosyl-tRNA
Synthetase by Insertion of a Stereospecific Editing Domain.
E.A. First, C. Richardson. LSU Hlth. Sci. Ctr. in Shreveport
and Univ. of Virginia.
1069.UBIQUITIN PATHWAY AND TARGETING
Exhibit Halls A-D
Poster
Exhibit Halls A-D
C90 1066.1 Tyrosine Phosphorylation of BipA and Its
Effect on the Binding Affinity of BipA. G. Blaha, A. Conn,
H. Fan, J. Hahm, S. Diggs, W. Preston, Y. Wang. Univ. of
C91 1066.2 Development of Glutaminyl-tRNA Synthetase
from Pseudomonas aeruginosa as a Platform to Screen for
Inhibitors of Protein Synthesis. Y. Escamilla, C. Hughes, Y. Hu,
J.M. Bullard. Univ. of Texas Rio Grande Valley.
C92 1066.3 Development of Prolyl-tRNA Synthetase
Inhibitors of Protein Synthesis. N. Pena, Y. Hu, J.M. Bullard.
Univ. of Texas Rio Grande Valley.
C93 1066.4 Development of Methionyl-tRNA Synthetase
Inhibitors of Protein Synthesis. S. Robles, Y. Hu, J.M. Bullard.
Univ. of Texas Rio Grande Valley.
C94 1066.5 Development of Arginyl-tRNA Synthetase from
Pseudomonas aeruginosa as a Platform to Screen for Inhibitors
of Protein Synthesis. D. Cantu, H. Salazar, J.M. Bullard. Univ.
of Texas Rio Grande Valley.
C100 1069.1 APOBEC3F-Vif Binding Interface Elucidated
by Multiple Experimental Approaches. R. Harris, C. Richards,
N. Shaban, B. Anderson, O. Demir, R. Amaro. Univ. of
Minnesota and HHMI, Minneapolis and UCSD.
C101 1069.2 Using Proteomics and Biochemical Approaches
to Evaluate the Function of SAKS1 in p97-Associated Process.
S. Li, T-F. Chou. Harbor-UCLA Med. Ctr. and LA Biomed. Res.
Inst. and Capital Med. Univ., Beijing.
C102 1069.3 Glucose
and
Calcium-Responsive
Phosphatases Mediate Crosstalk between Organelle and
Plasma Membrane Proton Pumps. S.D. Velivela, P.M. Kane.
SUNY Upstate Med. Univ.
C103 1069.4 Characterization of the HECT Domain Ubiquitin
Ligase Nedd4-2 D. Todaro, A. Augustus-Wallace, J. Klein, A.
Haas. LSU Hlth. Sci. Ctr., New Orleans.
353
T
U
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BIOCHEMISTRYTUESDAY
C104 1069.5 The HECTt Domain and RCC1-Like Domain
5/Herc5 Protein Exhibits Intrinsic Ubiquitin Ligase Activity. V.P.
Ronchi, J. Klein, F. Streich, A. Haas. LSU Hlth. Sci. Ctr., New
Orleans and Mem. Sloan-Kettereing Cancer Ctr.
C105 1069.6 The Role of Dictyostelium UbpA in Nutrient
Sensing and the Growth-to-Development Transition. M.R.
Behrens, V.J. Burghart, D.F. Lindsey. Walla Walla Univ.
C106 1069.7 A Novel Lysosomal GPCR Sorting Pathway
Regulated by Alpha-Arrestins and ALIX. M.R. Dores, H. Lin, J.
Trejo. UCSD.
C107 1069.8 Functional Analysis of DUF1 in Saccharomyces
cerevesiae R. Keuls, B. Lozzi, P. Anderson, F.L. Erickson.
Salisbury Univ.
C108 1069.9 Phenotypic Characterization of LRS1-2
Knockout Mutants in Arabidopsis thaliana B. Lozzi, R. Keuls,
P. Erickson, F.L. Erickson. Salisbury Univ.
C109 1069.10 Post-burn Regulation of Cardiac Protein
Synthesis and Degradation by IL-6 A. El Ayadi, A. Guillory,
A. Prasai, Y. Wang, C. Porter, D.N. Herndon, C.C.
Finnerty. Univ. of Texas Med. Branch and Shiners Hosp. for
Children, Galveston.
1070.RECENT ADVANCES IN
PROTEIN ENGINEERING
1071.CLINICAL PROTEOMICS
Poster
Exhibit Halls A-D
C119 1071.1 Digitoxin Treatment Reduces Nasal Epithelial
Cytokines in CF Subjects. S. Lee, D. Walker, P.L. Zeitlin.
Johns Hopkins Univ. and Sch. of Med.
1072.COMPUTATIONAL AND
ALGORITHMIC BIOLOGY
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C110 1070.1 A Novel Thermotolerant β-Glucosidase from
Aspergillus nidulans Has Activity across a Broad pH Profile and
a Likely Bacterial Origin. R. Auta, I. Radecka, P. Hooley. Univ.
of Wolverhampton, U.K. and Kaduna State Univ., Nigeria.
C111 1070.2 Assessment of CCN2 Independent Modules
Regenerative Capacity on Osteoarthritis and Further Selecting
the Most Suitable among Them as a Potential Therapeutic
Drug. T. Abdelkader, E. Aoyama, T. Nishida, T. Hattori, D.
Janune, E.S. Hara, M. Ono, Y. Tabata, T. Kuboki, S. Kubota,
M. Takigawa. Okayama Univ. and Kyoto Univ.
C112 1070.3 Hepatitis B Immunoglobulin Produced from
Long-Term Expansion of B Lymphocytes from Donors with
High Titer HBsAb. Y. Yang, C. Jie, J. Xu, X. Cai. Nanjing Red
Cross Blood Ctr., China.
C113 1070.4 Engineered
Mannose-Binding
Lectin
(FcMBL) Decreases Macrophage Phagocytosis. A. Chen, A.
Waterhouse, M. Rodas, G. Cuneo, A. Watters, M. Super,
D. Ingber. Simmons Col. and Wyss Inst. for Biol. Inspired
Engin., Boston.
C114 1070.5 Bioengineering of Human Heparin: A Next
Generation Anti-coagulant. J. Whitelock, B. Cheng, F. Tang,
G. Lyons, M. Lord. Grad. Sch. of Biomed. Engin., Univ. of New
South Wales, Sydney Med. Sch. and Royal Prince Alfred Hosp.
C115 1070.6 Uptake
and
Lysosomal
Delivery
of
Recombinant Human Alpha-N-Acetylglucosamine-6-Sulfatase
to Mucopolysaccharidosis IIID Fibroblasts. D.R. Moen, D.M.
Wang, X. Zhang, S-h. Kan, J. Wood, S. Ekins, T-F. Chou, P.I.
Dickson. LA BioMed at Harbor-UCLA and Phoenix Nest Inc.
and Jonah’s Just Begun, Brooklyn.
C116 1070.7 Investigating the DNA Binding Constraints of
the I-Sob2593 Meganuclease. R. Ruff, B. Kaiser. Seattle Univ.
354
C117 1070.8 Generation
of
Chimeric
High-Affinity
Monoclonal Antibody against DYKDDDDK Peptide (FLAG) K.
Ikeda, F. Sasaki, K. Saeki, T. Okuno, T. Koga, T. Yokomizo.
Juntendo Univ., Japan.
C118 1070.9 Aplip1 Regulates Dynein-Dependent but Not
Kinesin-Dependent Nuclear Movement in Muscle. J. Camuglia,
A. Auld, C. Murphy, E. Folker. Boston Col.
C120 1072.1 Comparative Genomics and Functional Analysis
of Carbohydrate Utilization Networks in Unicyanobacterial
Consortia Derived from Hypersaline Lake Microbial Mats. S.A.
Leyn, Y. Maezato, M. Romine, D.A. Rodionov. Inst. for Info.
Transmission Problems, Moscow, Sanford-Burnham-Prebys
Med. Discovery Inst., La Jolla and Pacific Northwest Natl. Lab.,
Richland, WA.
C121 1072.2 A Robust Computational Pipeline to Identify
Phenotype-Controlling Candidate Genes within a Quantitative
Trait Loci. A. Winnett, T. Gulick, S. Morey, R. Kesseli. Univ. of
Massachusetts Boston.
1073.COMPUTATIONAL APPROACHES IN
SYSTEMS BIOLOGY
Poster
Exhibit Halls A-D
C122 1073.1 Visualization Explorer for Classification and
Functional Enrichment of Fecal Microbiome to Metabolites. R.
Kumar, R. Yang, A. Gautam, R. Hammamieh, U. Mudunuri,
M. Jett-Tilton. Leidos Biomed Inc. NCI/Frederick and U.S.
Army Ctr. for Envrn. Hlth. Res., Fort Detrick, MD.
TUESDAYBIOCHEMISTRY
1074.EXPERIMENTAL AND COMPUTATIONAL
APPROACHES TO SYSTEMS
Poster
Exhibit Halls A-D
C123 1074.1 Integrating
Reductive
and
Synthetic
Approaches in Biology Using Man-Made Cell-Like
Compartments. W. Aoki, S. Komura, E. Tamiya, M. Ueda.
Kyoto Univ. and Osaka Univ.
C124 1074.2 Examining FOXO1 and DNA Interactions
through Computational and Direct Methods. B. McDaniel, T.
Cherlin, R. Haynes, M. Mottamal, D. Anderson, K. Johanson.
1075.FUNCTIONAL PROTEOMIC STUDIES
Poster
Exhibit Halls A-D
C125 1075.1 Sicpin, a Multifunctional Immunomodulatory
Salivary Protein from Black Flies Significantly Reduced T and B
Cell Proliferation and Directly Binds to Soluble CD4 Receptor.
E. Calvo, A.C. Chagas, J. Ribeiro. NIAID, NIH, Rockville, MD.
C126 1075.2 Proteomics-Enabled Hypothesis Generation
in Eosinophils: The Cases of LOC100996504, ARHGEF18
and NHS. L2 K. Turton, E. Wilkerson, F. Botros, J. Coon, D.
Mosher. Univ. of Wisconsin-Madison.
C127 1075.3 Purification and Expression of Rhodobacter
sphaeroides: A Predicted Dioxygenase. S.M. Neumann, C.
Nichols, B. Selinsky. Villanova Univ.
C128 1075.4 Characterization of Bacterial Homologs of
Prostaglandin H2 Synthase Using GC/MS. C. Nichols, M.
Butchy, B. Selinsky. Villanova Univ.
C129 1075.5 Characterization of a New Ferritin Protein
from the Polychaete Chaetopterus sp. N. Hamlish, E. De
Meulenaere, D. Deheyn. Wesleyan Univ.,CT, Scripps Instn. of
Oceanography and UCSD.
C130 1075.6 Functional Analysis of Suppressor of IKK&ε
in Migration and Phagocytosis. S.M. Fahey, F.A. Slykas, N.D.
DiChristofano, M.K. Dawood, J.K. Bell. Univ. of San Diego.
C131 1075.7 Characterization of Glycine Rich Proteins
in Amblyomma americanum R. Bullard, S. Karim. Univ. of
So. Mississippi.
1076.GENOMICS
Poster
Exhibit Halls A-D
C132 1076.1 Gene Expression Profiles of Various Rat Brain
Regions following Exposure to Soman. A. Gautam, B. Sowe,
D. Donohue, S-A. Miller, R. Hammamieh, J. Meyerhoff, M.
Pham, L. Lumley, M. Jett. Geneva Fndn., Tacoma, WA, U.S.
Army Ctr. for Envrn. Hlth. Res., Fort Detrick, MD and U.S.
Army Med. Res. Inst. of Chem. Defense, Aberdeen Proving
Ground, MD.
C133 1076.2 Genomic Characterization of Novel Genes
in the Novel Mycobacterium Phage Butters. M.C. Juarez, M.
Grajales, C.M. Mageeney, M.A. Kenna, V.C. Ware. Lehigh
Univ.
C134 1076.3 Signaling Regulators of TGF Cleavage Predict
Mechanisms for RTK Re-activation and Therapeutic Resistance
in Gastric Cancer. C. Harrison, J.L. Wilson, E. Fraenkel, A.
Herrlich, D. Lauffenburger. Univ. of Massachusetts Boston,
MIT and Harvard Insts. of Med.
C135 1076.4 Transcriptomic Analysis of Host Response
to the Karp Strain of Orientia tsutsugamushi in Inbred Mice
Blood. S-A. Miller, C-C. Chao, R. Yang, T-C. Chan, Z. Zhang,
H-W. Chen, W-M. Ching, R. Hammamieh, M. Jett-Tilton. U.S.
Army Ctr. for Envrn. Hlth. Res., Fort Detrick, Naval Med. Res.
Ctr., Silver Spring and Uniformed Svcs. Univ. of Hlth. Sci.,
Bethesda and NCI-Frederick Adv. Biomed. Computing Ctr.,
Fort Detrick, MD.
C136 1076.5 Characterization
of
YML020W
in
Saccharomyces cerevisiae K. Shoemaker, J. Keeney. Juniata
Col., PA.
C137 1076.6 Gene Expression Patterns in Trauma Patients:
A Systems Biology Approach. S. Srinivasan, D.E. Donohue,
A. Gautam, A.S. Conroy, M.F. Nelson, M.J. Cohen, R.
Hammamieh, M. Jett. The Geneva Fndn., Tacoma, San
Francisco Gen. Hosp. and U.S. Army Ctr. for Envrn. Hlth. Res.,
Fort Detrick, MD.
C138 1076.7 Comparative Genomics of Novel Phage
Leo1 Reveal a Promiscuous Cluster of Phage. S. Badran,
N. Morales, P. Schick, B. Jacoby, A. Geiger, S. Geiger, A.
Thummel, T.C. Lorenz. Univ. of La Verne.
C139 1076.8 Transcriptome Profiles of Porcine Skin
Dyschromia after Wound Injury. A. Alkhalil, S. Muhie, B.
Carney, T.E. Travis, L. Moffatt, L. Johnson, J. RamellaRoman, J. Shupp. MedStar Hlth. Res. Inst., Washington, DC,
Geneva Fndn., Frederick, MD, Georgetown Univ., MedStar
Washington Hosp. Ctr. and Florida intl. Univ.
1077.GLOBAL ANALYSIS OF PROTEIN FUNCTION
Poster
Exhibit Halls A-D
C140 1077.1 Refinement of the ProMOL Algorithm and
Determination of Function Based on Homology. S. Madha, M.
Lambrecht, J.L. Mills, H.J. Bernstein, P.A. Craig. Rochester
Inst. of Technol. Schs. of Life Sci. and Chem. & Materials Sci.
355
T
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BIOCHEMISTRYTUESDAY
1078.INTEGRATIVE PROTEOMICS OF
PROTEIN COMPLEXES
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C141 1078.1 Mapping Tyrosine Phosphorylation Networks
by Chemical Proteomics. W.E. Rogers, M. Ghassemian. San
Diego State Univ. and UCSD.
C142 1078.2 Purification and Biophysical Characterization
of the Photosystem I Complex from Botryococcus braunii
F.M. Joaquín Ovalle, G. Guihurt, Z. Torres-Martínez, Y.
Morales-Lozada, K. Griebenow. Univ. of Puerto Rico-Río
Piedras Campus.
1079.MICROARRAYS
Poster
Exhibit Halls A-D
C143 1079.1 Evaluation of the Gut Resistome and
Microbiome on Healthy Adults Receiving Antibiotic and a Multistrain Probiotic. C. MacPherson, O. Mathieu, V. Richard, A.
Nantel, T. Tompkins, S-A. Girard, P. Burguière. Lallemand
Hlth. Solutions Inc., Montreal, Sherbrooke Univ., Canada and
Natl. Res. Council Canada, Montreal.
1080.POSTTRANSLATIONAL MODIFICATIONS
(SYSTEMS BIOLOGY AND PROTEOMICS)
Poster
Exhibit Halls A-D
C144 1080.1 Comprehensive
Characterization
of
Glycosylation and Hydroxylation of Basement Membrane
Collagen IV by High-Resolution Mass Spectrometry. T. Basak,
L. Vega-Montoto, L. Zimmerman, D.L. Tabb, B.G. Hudson,
R.M. Vanacore. Vanderbilt Univ. Med. Ctr.
C145 1080.2 The Molecular Model of PKC Life Cycle
Explained through Systems Biology Approach. N. Aslam, F.
Alvi. BioSystOmics, Houston and COMSAT, Lahore.
C146 1080.3 Phosphorylation of Neuronal Proteins in
Drosophila melanogaster Changes with Age. A. Thomas, A.
Haberman. Univ. of San Diego.
356
1081.PROTEIN PROFILING IN NORMAL AND
DISEASE STATES
C147 1081.1 Proteomic Profiles of Vulvar Squamous Cell
Carcinoma Variants. E.R. Holthoff, S. Byrum, T. Kelly, A.
Tackett, C.M. Quick, S.R. Post. Univ. of Arkansas for Med. Sci.
C148 1081.2 Effect of over the Counter Teeth Bleaching
Products on the Proteins of Human Teeth. D. Swanson, K.
Keenan. Stockton Univ., NJ.
C149 1081.3 Electrochemical-Aptamer Biosensor against
ENOX2 for Cancer Diagnostics. L.C. Fetter, A.J. Bonham.
Metropolitan State Univ. of Denver.
C150 1081.4 Analysis of the Expression of the Basigin
Subset of the Immunoglobulin Superfamily in Mouse Brain.
T.N. Hall, J.D. Ochrietor. Univ. of North Florida.
C151 1081.5 Mass Spectrometry-Based Proteomics of
Human Breast Milk to Assess Breast Cancer Risk. R. Aslebagh,
D. Channaveerappa, K.F. Arcaro, C.C. Darie. Clarkson Univ.
and Univ. of Massachusetts Amherst.
C152 1081.6 Host Urinary Proteins Changed Significantly in
Mice Infected with Malaria. X. Li, W. Deng, H. Wang, Y. Gao.
Inst. of Basic Med. Sci., Chinese Acad. of Med. Sci. and Beijing
Normal Univ.
C153 1081.7 Proteomic Analysis of Ewing’s Sarcoma Cell
Lines. R. Thompson, A. Kruchten. Linfield Col., OR.
1082.METHODS
Poster
Exhibit Halls A-D
C154 1082.1 Integrin β1 and ICAM-1; Enrich Markers for
Isolating Rat Mesenchymal Stem Cells from Bone Marrow.
E.G. Suto, Y. Mabuchi, N. Suzuki, Y. Ogata, C. Akazawa.
Grad. Sch. of Hlth. Care Sci., Tokyo Med. and Dent. Univ.
C155 1082.2 Are Enzymes Required for the Extraction
and Isolation of DNA in Conjunction with Mechanical
Homogenization? B.A. Easparro, S. Garrett, J. Atwood. Omni
Intl., Kennesaw, GA.
C156 1082.3 Evaluating the Extraction Efficiency of Food
Borne Pathogens on Automated Homogenizer Platforms. S.
Garrett, J. Atwood, B. Easparro. Omni Intl., Kennesaw, GA.
C157 1082.4 Development of an Easy, Inexpensive,
and Precise Method to Identify Hemoglobin C for Use in
Underdeveloped Countries. C.D. Ohiri, T.R. Randolph. Saint
Louis Univ.
C158 1082.5 Optimization of Falling Drop Copper Sulfate
Method to Quantify Hemoglobin Concentration. R.K. Sinha,
T.R. Randolph. Saint Louis Univ.
C159 1082.6 High Throughput Single Cell Gene Expression
Profiling by Multiplex qPCR. S. Okino, M. Kong, J. Ma, J.
Fenrich, Y. Jouvenot, Y. Wang. Bio-Rad Labs., Hercules, CA.
TUESDAYBIOCHEMISTRY
C160 1082.7 Accurate Quantification of Choline and
Ethanolamine Plasmalogen Molecular Species by Liquid
Chromatography Coupled with Tandem Mass Spectrometry.
Y. Otoki, S. Kato, F. Kimura, K. Furukawa, H. Arai, K.
Nakagawa, T. Miyazawa. Tohoku Univ., Univ. of California,
Davis and Nippon Med. Sch.
C161 1082.8 Quantifying HbF Using a Modified KleihauerBetke Assay. R. Singh, T.R. Randolph. Saint Louis Univ.
C162 1082.9 a New Approach to Characterize the
Molecular Interactions between Tio2 Nanoparticles and Dietary
Flavonoids Using Surface-Enhanced Raman Spectroscopy. X.
Cao, Z. Gao, J. Zheng, L. He, H. Xiao. Univ. of Massachusetts
Amherst and Chinese Acad. of Agr. Sci., Beijing.
C163 1082.10 Diet Alters Age-Related Remodeling of Aortic
Extracellular Matrix in Mice Susceptible to Atherosclerosis.
S.R. Watson, P. Liu, E.A. Pena, S.M. Han, S.M. Lessner. Univ.
of South Carolina Sch. of Med. and Univ. of South Carolina.
C164 1082.11 Using Polymerase Chain Reaction Inhibition
to Study Small Molecule Binding to DNA. R. Ghannam, S.R.
Smith, M.A. Benore. Univ. of Michigan-Dearborn.
C165 1082.12 Purification and Characterization of DNA from
Fresh versus Frozen Chicken Embryos. J. Byk, S.R. Smith,
M.A. Benore. Univ. of Michigan-Dearborn.
C166 1082.13 Characterizing Heterogeneity of Cancer Stem
Cells Using Raman Microscopy. H. Zhang, F. Xu, L. He, H.
Xiao. Univ. of Massachusetts Amherst.
1083.ENZYME MECHANISM
Poster
Exhibit Halls A-D
C167 1083.1 Histone Deacetylase 6: Structure, Mechanism,
and Inhibitor Selectivity. Y. Hai, D. Christianson. Univ.
of Pennsylvania.
C168 1083.2 Relating Intein Flexibility to the Temperature
Dependence of Activity. A.E. Yakely, A.A. Bonano, M.V.
Jaramillo, J.E. Williams, J.N. Reitter, K.V. Mills. Col. of the
Holy Cross, MA.
C169 1083.3 Influence of Intein Flexibility on Temperature
Dependence of Protein Splicing. J.D. Long, I. Pierre, J. Reitter,
K.V. Mills. Col. of the Holy Cross, MA.
C170 1083.4 An Investigation of Salt-Dependent Protein
Splicing. C.E. Cousin, J.N. Reitter, M. Nicastri, M.S. Jaramillo,
C171 1083.5 A Biophysical Analysis of Aspartic Acid
Cyclization Coupled to Peptide Bond Cleavage. M.
Koulopoulos, Z. Giaccone, J. Reitter, K. Mills. Col. of the
Holy Cross, MA.
C172 1083.6 The Influence of Conserved Residues
and Structural Elements on the Stability and Activity of a
Thermophilic Intein. C.J. Minteer, K.M. Colelli, J.N. Reitter,
C173 1083.7 Dissection of DNA Synthesis In Crystallo
Reveals a Third Mg2+ in the Transition State. Y. Gao, W. Yang.
NIDDK, NIH.
C174 1083.8 The Tale of Two Inteins: Similar Inteins with
Different C-Termini. C.K. Ramsoomair, Z.T. Giaccone, J.N.
Reitter, K.V. Mills. Col. of the Holy Cross, MA.
C175 1083.9 9(Z),12(Z)-Eicosadienoic Acid as a Probe
for Substrate Binding by Soybean Lipoxygenase-1 D.J.
Hinnenkamp, C.H. Clapp. Bucknell Univ.
C176 1083.10 Phenotypic
Studies
of
PHO13Δ
in
Saccharomyces cerevisiae C. Kellogg, K.J. Mills, S.
O’Handley, A.U. Gehret. Sch. of Chem. and Mat. Sci. and
Natl. Tech Inst. for Deaf, Rochester Inst. of Technol.
C177 1083.11 Flavin-N5-Oxide: A New Redox State in Flavin
Enzymology. A. Sapra, B. Palfey. Univ. of Michigan.
C178 1083.12 Comparison of Enzymatic Activities of
Pokeweed Antiviral Protein Isoforms toward RNA from the
Tobacco Etch Virus. V.R. Aitbakieva, A.V. Domashevskiy.
John Jay Col. of Criminal Justice, NY.
C179 1083.13 Deciphering the Metal Dependency of Novel
Nicotinate Hydroxylase from Bacillus niacini J.A. Meek, L.A.
Sherer, M.J. Snider. The Col. of Wooster.
C180 1083.14 Identification and Purification of a Serine
Protease Involved in Cell-Mediated Immunity in Fish. Y.
Matsuura, T. Yabu, H. Shiba, T. Nakanishi. Nihon Univ., Japan.
C181 1083.15 Effects of Mutation at Position 557 on the
Catalytic Properties of Soybean Lipoxygenase-1 N.F. Bassett,
C.H. Clapp. Bucknell Univ.
C182 1083.16 Protein-Protein Interactions Reduce Ca2+Requirements for Transglutaminase 2 Mediated Posttranslational Modifications of α-Synuclein. T.N. Zeczycki, J.S.
Viscomi. Brody Sch. of Med. at East Carolina Univ.
C183 1083.17 Using Mutagenesis and Synthetic Substrates
to Explore Regiochemical Control by Soybean-Lipoxygenase-1
C.H. Clapp, K.M. Kahler, P. Plumeri, F. Karaisz, C.R. Dodson.
Bucknell Univ.
C184 1083.18 Investigating
the
GCN5
Histone
Acetyltransferase Chemical Mechanism. B.H. Young, C.E.
Berndsen. James Madison Univ.
C185 1083.19 Spectroscopic
and
Electrochemical
Characterization of a Unique Radical S-Adenosylmethionine
Methylase. A.J. Blaszczyk, A. Silakov, B. Zhang, S.J.
Maiocco, N.D. Lanz, W.L. Kelly, S.J. Elliott, C. Krebs, S.J.
Booker. HHMI, Penn State, Boston Univ. and Georgia Tech.
C186 1083.20 Avoiding the Carbapenem Trap: KPC-2
β-Lactamase Sequence Requirements for Carbapenem
Hydrolysis. S.C. Mehta, M. Samanta, D-C. Chow, T. Palzkill.
Baylor Col. of Med.
C187 1083.21 Identification of Mechanistic Targets for
Optimization of a Cyanobacterial Hydrocarbon Production
Bioprocess. E. Beardsley, L. Rajakovich, M-E. Pandelia, C.
Krebs, M. Bolinger, S.J. Booker. Univ. of Mount Union, OH
and Penn State.
C188 1083.22 The Role of Lys42 on the Catalytic Efficiency
of the ADP-Glucose Pyrophosphorylase from Escherichia coli
A.L. Mahaffey, S. Aiyash, M.A. Ballicora. Loyola Univ. Chicago
and Stritch Sch. of Med. Loyola Univ. Chicago, Maywood.
C189 1083.23 Substrate-Induced Structural Changes in the
Mevalonate Diphosphate Decarboxylase from Enterococcus
faecalis. C-L. Chen. Purdue Univ.
357
T
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BIOCHEMISTRYTUESDAY
1084.RADICALS IN CATALYSIS
Poster
Exhibit Halls A-D
C190 1084.1 New Function of Enzyme Involved in the
Formation of a Carbon-Nitrogen Triple Bond. M. Kobayashi.
Grad. Sch. of Life and Envrn. Sci., Univ. of Tsukuba.
C191 1084.2 Radical SAM Enzyme-Catalyzed Formation
of Thioether Crosslinks in Ribosomal-Produced Peptides:
Formation of the RiPP Natural Product Thuricin CD by the
Radical Sam Enzymes TrnC and TrnD. J.T. Jarrett, C.E.
Holjencin. Univ. of Hawaii at Manoa.
1085.STRUCTURAL STUDIES OF COMPLEX SYSTEM
Poster
Exhibit Halls A-D
C197 1087.2 Comparison of Stability and Kinetic Properties
of DszB from N. asteroides A3H1 and R. erythropolis IGT. S8
A. Hutchinson-Lundy, A. Crithary, J.M. Schmitz, L. Watkins.
James Madison Univ.
1088.CHEMICAL COMMUNICATION AND
SIGNAL TRANSDUCTION
Poster
Exhibit Halls A-D
C198 1088.1 Precise Redox Responses Imprinted by OnDemand Redox Targeting. Y. Aye. Cornell Univ. and Weill
Cornell Med., Ithaca.
C199 1088.2 A Spatiotemporal-Controlled Targeting Tool
for Understanding the Roles of Redox Signals on Bacterial
Growth. V.N. Pham. Cornell Univ.
C200 1088.3 Entamoeba spp. as Models for the Effects
of Environmental Stress in Protists. M. Hackey, J. Leitao, A.
Espinosa. Roger Williams Univ., RI
C192 1085.1 Structure of a Key Intermediate in the Reaction
Catalyzed by the Dual Specificity Methylase RlmN. E.L.
Schwalm, T. Grove, A. Boal, S. Booker. Penn State and HHMI.
C193 1085.2 UV Mutagenesis Enhance Function of
Cellobiohydrolase I Gene of Aspergillus niger M.O. Babalola,
O.A. Magbagbeola, A.O. Ebuehi, V.I. Okochi. Univ. of
Lagos, Nigeria.
C194 1085.3 The NMR Model of the 39-kDa Tri-Domain IsdH
Protein from Staphylococcus aureus Suggests That It Uses
Inter-domain Motions to Recognize Human Hemoglobin and
Promote Heme Release. M. Sjodt, R. Macdonald, D.A. Gell,
J.S. Olson, R.T. Clubb. UCLA, Univ. of Tasmania, Australia
and Rice Univ.
1086.ROLE OF DYNAMICS IN ENZYME CATALYSIS
Poster
Exhibit Halls A-D
C195 1086.1 Sifting through the Haystack to Find the Needle:
Spatial Identification of a Structural Conduit for Transfer of
Thermal Activation Energy in the Course of C-H Cleavage in
Soybean Lipoxygenase. A. Offenbacher, S. Hu, A. Nguy, A.
Iavarone, J. Klinman. Univ. of California, Berkeley.
1087.CHEMICAL BIOLOGY OF SUSTAINABILITY
Poster
Exhibit Halls A-D
C196 1087.1 Effect of Immobilization on the Stability and
Specificity of Choline Oxidase. J.M. Schmitz, L. Watkins.
James Madison Univ.
358
1089.CHEMICAL PROBES AND THEIR USE IN
IDENTIFYING NEW THERAPEUTIC TARGETS
Poster
Exhibit Halls A-D
C201 1089.1 Concentration
Effects
in
Identifying
Unclumping Reagents. G. Zem, E. Mikaelian, L. Quinones,
C. Nwokochah, F. Osadi, D. Arana, S. Barsigian, J. Dugyawi,
B. Alvarado, G. Hovakemian, J. Lam, M. Eskander, M.
Voldiner, S. Garcia, D. Nair, J. Song, G. Tashdjian, S. Nazer,
S. Rashidizand, G. Constantino, N. Pilikian, A. Faretta, H.
Gekchyan, L. Corscadden, M. Kelvani, K. DeGuzman, R.
Canta, S. Korkounian, A. Strelnicova, M. Turdjian, M. Lay,
A. Darmali, N. Memarian, K. Simonyan, L. Oghlian, S.B.
Oppenheimer. California State Univ., Northridge.
C202 1089.2 Statistical Analysis of Kinetic Profiles of
Anti-clumping Agents. G. Zem, H. Hakobyan, S. Terteryan,
T. Baronian, E. Mikaelian, E. Vozovoy, T. Baum, S.B.
Oppenheimer. California State Univ., Northridge.
C204 1089.4 Sensitive Serologic Detection of Pathogenic
Mycoplasma via Electrochemical Biosensor. J. Jacobs, A.J.
Bonham. Metropolitan State Univ. of Denver.
C205 1089.5 The Synthesis and Characterization of
Potential Covalent Probes for Chronic Lymphocytic Leukemic
B-Cell Receptors Using Sulfonyl Fluoride. P. Rohweder, T.
Kodadek, M. Sarkar, C. Dreyer, H. Park. The Col. of Wooster
and The Scripps Res. Inst.
TUESDAYBIOCHEMISTRY
1090.MODE OF ACTION OF BIOACTIVE
NATURAL PRODUCTS
Poster
Exhibit Halls A-D
C206 1090.1 Anti-microbial Properties of Plants Native to
the Philippines and to Minnesota. B.M. Pethke. Saint Mary’s
Univ. of Minnesota.
C207 1090.2 The Effect of Phytochemicals on a
Chemoresistant,
Epithelial-Mesenchymal
Transitioned,
Colorectal Cancer Cell Line. K. Murden, K. San, A. Martino,
U. Ezekiel. Saint Louis Univ.
C208 1090.3 Anonna squamosa Leaves Ethanolic Extract
Mediates Apoptosis through Heat Shock Protein Mitigation and
G2/M Cell Cycle Arrest in Human Hepatocellular Carcinoma
(SK-Hep1) Cells. W.M.L. Lumbera, E.J.S. Vergara, Y.S. Kim,
J.F. dela Cruz, S.G. Hwang. Hankyong Natl. Univ., Korea and
Univ. of the Philippines Los Banos.
C209 1090.4 Chemotherapeutic Potential of Averrhoa
bililmbi Leaves Ethanolic Extracts against Human Colorectal
Carcinoma through Anti-inflammatory Activity in Murine RAW
264.7 Macrophage Cells and Anti-proliferative Activities against
HT-29 Human Colorectal Carcinoma. E.J.S. Vergara, Y.S. Kim,
W.M.L. Lumbera, T.L. Nguyen, J.F. dela Cruz, S.G. Hwang.
Hankyong Natl. Univ., South Korea and Col. of Vet. Med., Univ.
of the Philippines Los Baños.
C210 1090.5 The Peptide Ixosin Uses an ATCUN Motif for
Its Oxidative Antimicrobial Activity and Its Synergy with Ixosin
B. M.D.J. Libardo, V.Y. Gorbatyuk, A.M. Angeles-Boza. Univ.
of Connecticut.
C211 1090.6 The Anti-proliferative Effects of Curcumin
Derivatives, Dimethoxycurcumin, Bisdemethoxycurcumin
and Tetrahydrocurcumin, on DLD-1 Colon Cancer Cells. N.
Khatwani, T. Adeyeni, U. Ezekiel. Saint Louis Univ.
C212 1090.7 Characterization of the Role of Phenolic
Compounds in the Inhibition of α-Amylase by Kombucha
Tea. S.R. Armando, R.A. Schneider, F.M. Mann. Winona
State Univ.
C213 1090.8 In Vitro Evaluation of Cytotoxic and Antioxidant
Activity of Essential Oil and Terpenes of Satureja macrostema
R. Salgado-Garciglia, R. Torres-Martínez, A. HernándezGarcía, A. Saavedra-Molina, J.E. López-Meza, A. OchoaZarzosa. Univ. Michoacana de San Nicolás de Hidalgo, Mexico.
C214 1090.9 In Vivo Activity of Ethanolic Extracts of Leaves
and Stems Bark of Alstonia boonei against Plasmodium
berghei in Female Albino Mice. O.F. Onifade, N.V. Atasie, I.U.
Fakankun, V. Maganda. Bells Univ. of Technol., Nigeria.
C215 1090.10 Induction of Apoptosis in DLD-1 Colorectal
Cancer Cells Using Water Soluble Compounds from Rumex
crispus M. Bhandari, H. Lockwood, B. Clack. Stephen F
Austin State Univ.
C216 1090.11 Antiproliferative Effect of Resveratrol and
Oxaliplatin on Colon Cancer Cells. N.P. Daniel, U. Ezekiel.
Saint Louis Univ.
1091.OMICS APPROACHES IN CHEMICAL BIOLOGY
Poster
Exhibit Halls A-D
C217 1091.1 A Chemical Glycoproteomics Platform to Study
the Human Prostate Secretome. D.R. Spiciarich, S. Purcell,
S.L. Maund, D.M. Peehl, C.R. Bertozzi. Univ. of California,
Berkeley and Stanford Univ. Sch. of Med.
1092.PROTEIN-SMALL MOLECULE INTERACTIONS
Poster
Exhibit Halls A-D
C218 1092.1 Stabilin-Mediated Cellular Internalization of
Phosphorothioate-Modified Antisense Oligonucleotides. C.M.
Miller, A.J. Donner, E.K. Blank, A. Eggar, B. Kellar, P.P. Seth,
E.N. Harris. Univ. of Nebraska-Lincoln and ISIS Pharmaceuts.
Inc., Carlsbad.
C219 1092.2 Synthesis
of
Effective
Water-Soluble
Fluorescein Dibenzyl Ether Cytochrome P450 Substrates.
C.M. Stepler, M.A. Gallivan, L.M. Wysocki. Wabash Col., IN.
C220 1092.3 Influence of NSAID Flurbiprofen on Protein
Helix-Helix Interactions. N. Gugala, R.J. Turner. Univ. of
Calgary, Canada.
C221 1092.4 Mechanism of SAMT Analog Inactivation of
HIV-1 Gag Polyprotein. E.L. Paine, K.M. George Rosenker,
M.T. Scerba, L. Deshmukh, D.H. Appella, L.M. Miller Jenkins.
NCI, NIH and NIDDK, NIH.
C222 1092.5 New Tricks for an Old Drug: Inhibition
of
Glyceraldehyde-3-Phosphate
Dehydrogenase
by
Dithiolethiones to Suppress Cancer Cell Proliferation. M.R.
White, T.W. Miller, C. Switzer, J. Chavis, P. Xu, D. Roberts,
D. Wink, E.D. Garcin. Univ. of Maryland Baltimore County and
NCI, NIH.
C223 1092.6 Small Molecule Binding Sites Explored in
Variable Heavy Chain Antibodies. B.R. White, S.J. Gee, B.J.
Hammock, C.R. Brooks. California State Univ., Fresno and
Univ. of California, Davis.
C224 1092.7 Determination of HNO-Derived Modifications
on the Cardiac Protein Phospholamban. G. Keceli, A.
Majumdar, C.N. Thorpe, J.E. Mahaney, N. Paolocci, J.P.
Toscano. Johns Hopkins Univ., Edward Via Col. of Osteo.
Med., VA and Johns Hopkins Med. Instns.
1093.BACTERIAL GLYCOSYLATION AND
THE MICROBIOME
Poster
Exhibit Halls A-D
C225 1093.1 Chemoenzymatic Synthesis of a Novel Sugar
Scaffold for Targeting Ligand Development. K.M. Erickson,
J.M. Hazel, J.M. Troutman. Univ. of North Carolina at Charlotte.
359
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BIOCHEMISTRYTUESDAY
1094.CARBOHYDRATE ACTIVE ENZYMES
Poster
Exhibit Halls A-D
C226 1094.1 Reversible Glucan Phosphorylation Requires
Unique Carbohydrate Binding Platforms. M. Gentry, C.
Vander Kooi, M. Raththagala, D. Meekins, K. Brewer. Univ.
of Kentucky.
1095.CHEMICAL BIOLOGY APPROACHES TO
UNDERSTAND GLYCAN-RELATED DISEASES
Poster
Exhibit Halls A-D
C227 1095.1 The Lack of Cardiomyocyte Complex and
Hybrid N-Glycans Result in Arrhythmic Dilated Cardiomyopathy,
Heart Failure, and Premature Death. A.R. Ednie, L.N. Darville,
W. Deng, E.S. Bennett. Univ. of South Florida.
C228 1095.2 Glycome Sequencing; Are We There Yet? V.N.
Reinhold. Univ. of New Hampshire.
C229 1095.3 Bacterial Cell Wall Remodeling to Study the
Production of Immunoactivating Fragments. H. Liang, K.E.
DeMeester, C-W. Hou, C.L. Grimes. Univ. of Delaware.
C230 1095.4 Human-Specific Derived Alleles of CD33 and
Other Genes Protect against Post-reproductive Cognitive
Decline. S.A. Springer, F. Schwarz, T. Altheide, N.A. Varki, P.
Gagneux, A. Varki. UCSD.
C231 1095.5 ABO Blood Type Correlates with Survival
on Prostate Cancer Vaccine Therapy. J. Gildersleeve. NCI
at Frederick.
1096.PROTEIN-CAROHYDRATE INTERACTIONS
1097.STRUCTURAL BIOLOGY OF CARBOHYDRATEPROTEIN INTERACTIONS
Poster
Exhibit Halls A-D
C235 1097.1 Introducing Glycans to Molecular Visualization
Software. D.F. Thieker, J. Hadden, J. Stone, R. Woods. Univ.
of Georgia and Univ. of Illinois at Urbana Champaign.
C236 1097.2 Carbohydrate-Protein Interactions with Polyamido-saccharides as Unique Carbohydrate-Inspired Polymer
Structures. S.L. Chin, M.W. Grinstaff. Boston Univ.
C237 1097.3 High Affinity Binding of a MUC1 Specific
Antibody to a Glycopeptide Mediated by Conformational
Selection. C.L. Brooks, R. Movahedin, T.M. Brooks, N.
Supekar, G-J. Boons. California State Univ., Fresno and Univ.
of Georgia.
C238 1097.4 Glycosylation Alters Oligomerization Status
of the Human CEACAM1-IgV Domain. J.H. Prestegard, K.
Moremen, Y. Zhuo, J-Y. Yang. Univ. of Georgia.
1098.BIOCHEMICALLY-INFORMED IMAGING IN
DRUG DISCOVERY
Poster
Exhibit Halls A-D
C239 1098.1 Longitudinal Monitoring of Nanoparticle
Accumulation in PC-3 Tumors. J.C. Nneji, C.A. Gharagouzloo.
Northeastern Univ.
C240 1098.2 Targeting
Peptide
Bound
to
Major
Histocompatibility Complex Allows Visualization of Insulin
Secreting Beta Cells In Vivo. K.R. Miller, J. Taft, A. Koide, M.
Johnson, R. Tisch, S. Koide, E. Collins. Univ. of Mount Union,
Univ. of Chicago and Univ. of North Carolina at Chapel Hill.
Poster
Exhibit Halls A-D
C232 1096.1 Location and Partners of Polysialic Acid
in the Dorsal Horn and Trigeminal Nucleus of Adult Rat. S.
Shahbazian, A. Lee, A. Everest-Dass, P. Bokiniec, N.
Packer, A. Goodchild. Macquarie Univ., Australia.
C233 1096.2 Probing the Interactions between α-1,
4-Mannobiose Molecules, Using AFM. K.H. Perera, S. Basu,
P. Chandran. Howard Univ.
C234 1096.3 The C. albicans Adenylyl Cyclase, CYR1p,
Binds Bacterial Cell Wall Fragments via Its LRR Domain. J.
Burch, A. Schaefer, M. Lauro, J. Melnyk, J. Glowala, D.
Wykoff, C.L. Grimes. Univ. of Delaware and Villanova Univ.
360
1099.METABOLISM AND CANCER
Poster
Exhibit Halls A-D
C241 1099.1 Novel Small Molecule, WZB117, Competitively
Inhibit GLUT1-Mediated Glucose Transport to Halt Cancer
Growth. O. Ojelabi, J. DeZutter, K. Lloyd, A. Carruthers.
Univ. of Massachusetts Med. Sch.
C242 1099.2 Activation of LXR Inhibits the Development of
Pulmonary Carcinomas Induced by 3-Methylcholanthrene and
Butylated Hydroxytoluene. Y. Liu, Q. Wang, X. Ma, Y. Chen, L.
Sun, Y. Duan, J. Han. Nankai Univ., China.
TUESDAYBIOCHEMISTRY
C243 1099.3 Axin Is Localized within Mitochondria and
Regulates Energy Metabolism through Alterations of Oxidative
Phosphorylation and Glycolysis. J-H. Shin, S-H. Kee.
Korea Univ.
C244 1099.4 Calcium Sulfide Nanostructure Treatment on
Non-small Cell Lung Cancer. K. Muñoz Forti, M. Figueroa, B.
Torres, F. Bernard, D. Rivera, M.E. Castro, E.B. Suarez. Univ.
of Puerto Rico at Ponce and Univ. of Puerto Rico at Mayaguez.
C245 1099.5 MboII Restriction Fragment Length Analysis of
Estrogen Receptor 1 Gene. M.G. Saibu, J. Ayorinde, O. Adu,
F. Faduyile, D. Wusu, O. Iyapo, M. Kazeem, S. Soyemi, S.
Izuagie. Lagos State Univ., Univ. of Lagos Akoka, University
Col. Hosp., Ibadan and Caleb Univ., Nigeria.
C246 1099.6 Claudin-7 Regulates Survival and Glucose
Metabolism of Human Lung Cancer Cells. D.H. Kim, S.M.
Jackson, Y-H. Chen, Q. Lu. East Carolina Univ.
C247 1099.7 A Novel Role for the Extracellular Matrix
in Regulation of Hepcidin in Breast Cancer Spheroids. N.
Blanchette, L. Tesfay, D. Kita, K.P. Claffey, F.M. Torti, S.V.
Torti. Univ. of Connecticut Hlth.
C248 1099.8 Upregulated Expression of GRP78 Supports
ER Stress-Induced Apoptosis in Tunicamycin-Treated Triple
Negative Breast Tumor. D.K. Banerjee, A. Banerjee, Z.
Zhang, J.E. Serrano, E.C. Romero, N. Sanchez, K. Baksi.
Univ. of Puerto Rico, San Juan and Univ. Central del Caribe,
Bayamon, PR.
C249 1099.9 The Bioactive Properties of Acetone Extract of
Cola acuminata in Breast Cancer Cells. J. McGovern, W. Gray.
Southern Univ. A&M Col.
C250 1099.10 Common Jamaican Herbal Medicine, Bizzy
Nut, Inhibits Cell Cycle in Prostate Cancer Cells. W. Gray, A.
Chumbow, O. Phillips. Southern Univ. A&M Col., LA.
C251 1099.11 Analysis of the Calyces from the Jamaica
Species of Hibiscus sabdariffa for Adrogenic Compounds. L.Y.
Butler, M. Morgan, W. Gray, K. Chin, J. Snowden.
Southern Univ. A&M Col.
C252 1099.12 Level of Polycyclic Aromatic Hydrocarbons
and Heavy Metals in Selected Facial Makeup Cosmetics
Commonly Used in Lagos, Nigeria. M.N. Igwo-Ezikpe, F.O.
Taiwo, O.T. Sotinala. Col. of Med., Univ. of Lagos.
C253 1099.13 Novel Role for Lysocardiolipin Acyltransferase
in Non-small Cell Lung Cancer. S.R. Kotha, L. Huang, M.M.
Van Scoyk, S. Avasarala, R.A. Winn, R.K. Bikkavilli, V.
Natarajan. Univ. of Illinois at Chicago.
C254 1099.14 Experimentally-Induced Melanoma Has an
Heterogeneous Oxidative Metabolism and Induces Peritumoral Innervation Remodeling. R. Noriega-Cisneros, F.X.
Rosas-Plaza, J. Ramírez-Santos, G. Gutierrez-Ospina. Fac,
of Vet Med. and Animal Husbandry and Inst. of Biomed. Res.,
Natl. Autonomous Univ. of Mexico.
C255 1099.15 Enzymes Running in Reverse: Catalytic
Studies on Isocitrate Dehydrogenase Mutations Implicated in
Cancer. C. Sohl, D.A. Matteo, A. Grunseth, S. Anselmo, E.
Gonzalez, M. Kennedy. San Diego State Univ.
C256 1099.16 Multiple Glutamine Transporters Sustain
the Growth of Glutamine Synthetase-Negative Human
Oligodedroglioma Cells. M. Chiu, C. Sabino, M. Allegri, M.G.
Bianchi, O. Bussolati. Univ. of Parma.
C257 1099.17 Metformin Modulation of DichloroacetateInduced Oxidative Stress and Its Impact on Mitochondrial
Integrity in VM-M3 Glioblastoma Cells. N.P. Ward, A.M. Poff,
A.P. Koutnik, D.P. D’Agostino. Univ. of South Florida.
C258 1099.18 Differential Regulation of mTORC1 by Amino
Acids. J.L. Jewell, K-L. Guan. Univ. of Texas Southwestern
Med. Ctr. and UCSD.
C259 1099.19 PDK2 Mediated Alternative Splicing Switches
Bnip3 from Cell Death to Cell Survival. L. Kirshenbaum, H.
Gang, R. Dhingra, J. Lin, Y. Hai, V. Margulets. St-Boniface
Hosp. Res., Winnipeg, Canada.
C260 1099.20 Expression of Folate Transport Proteins Are
Decreased in Head and Neck Squamous Cell Carcinoma.
J.M. Green, K. Cuadros, J. Goral, B. Jham, E.P. Guimaraes,
J.A.C. Hanneman. Midwestern Univ., IL and Fed. Univ. of
Alfenas, Brazil.
C261 1099.21 Self Activation of IGF1R Signaling by Cancer
Cells Confers a Paracrine Metabolic Advantage. G. Lenz, A.
Hamilton, J. Huss, S. Kane. City of Hope Natl. Med. Ctr.,
Pasadena and Duarte.
C262 1099.22 Physiological Role of DAB2IP in Regulating
the Activity of Glycolysis in Prostate Cancer. Y. Li, J. Jea, R-C.
Pong, J.Yang, G. Xiao, D.A. Boothman, J-T. Hsieh. Kaohsiung
Med. Univ., Taiwan and Univ. of Texas and Southwestern
Med. Ctr.
C263 1099.23 Treadmill Exercise Decreases Aberrant Crypt
Foci Lymph Associated in the Large Intestine of Obese Mice.
A. Kriska, R. Emmons, P. Jung, B. Xu, M. De Lisio, Y-X. Pan,
H. Chen. Univ. of Illinois at Urbana-Champaign.
C264 1099.24 CD44+/CD25-/CD100+ Cells Contribute to
the Development of Basal Epithelial-Like Metaplastic Breast
Cancer in Adiponectin-Deficient MMTV-PyVT Mice. J. Chen,
H. Cao, J. Liu, W.C. Tse, I-K. Lee, P.M. Vanhoutte, A. Xu, W.
Yu. The Univ. of Hong Kong and Kyungpook Natl. Univ. Sch. of
Med., South Korea.
1100.MITOCHONDRIA IN HEALTH AND DISEASE
Poster
Exhibit Halls A-D
C265 1100.1 A Model for the Function of CoQ9: The
Isoprenoid-Precursor Presenter. M.S. Stefely, D.C. Lohman,
D.J. Pagliarini. Univ. of Wisconsin-Madison and Morgridge
Inst. for Res., Madison.
C266 1100.2 Mitochondria as Signaling Organelles in Aging.
V. Titorenko, A. Leonov, A. Arlia-Ciommo, Y. Medkour, V.
Svistkova. Concordia Univ., Canada.
C267 1100.3 Mitochondrial Transfer by Photothermal
Nanoblade Restores Respiration in Mammalian Cells with
Dysfunctional Mitochondria. A.N. Patananan, T-H. Wu, E.
Sagullo, D. Case, X. Zheng, Y. Li, J. Hong, T. TeSlaa, J.M.
McCaffery, K. Niazi, D. Braas, C. Koehler, T. Graeber, P-Y.
Chiou, M. Teitell. UCLA, Johns Hopkins Univ. and NantWorks,
Culver City, CA.
C268 1100.4 Mitochondrial Protein Functions Revealed
by Global Protein-Lipid-Metabolite Profiles. D.J. Pagliarini,
J.A. Stefely, N. Kwiecien, A. Hebert, M. Veling, A. Richards,
A. Ulbrich, A. Jochem, M. Rush, E. Freiburger, H. Marx,
M. Westphall, J. Coon. Morgridge Inst. for Res. and Univ.
C269 1100.5 Methylene Blue Alleviates Nuclear and
Mitochondrial Abnormalities in Hutchinson-Gilford Progeria
Syndrome. Z. Xiong, J.Y. Choi, K. Wang, H. Zhang, Z. Tariq,
D. Wu, K. Cao. Univ. of Maryland College Park.
361
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BIOCHEMISTRYTUESDAY
C270 1100.6 Combined BH3 and Metabolic Profiling as a
Method to Define Therapeutic Response and Resistance in
Grade IV Astrocytomas. M. Rodriguez Silva, S. GonzalezArias, J.W. Chambers. Herbert Wertheim Col. of Med., Florida
Intl. Univ.
C271 1100.7 TCA Cycle Defects in Barth Syndrome. W.
Lou, Y. Li, A.S. Joshi, J.L. DeLeeuw, N. Saadat, C. Reynolds,
S.V. Gupta, S. Trimpin, M.L. Greenberg. Wayne State Univ.
C272 1100.8 Effects of Turnera diffusa Will over Blood
Glucose and Oxidative Stress in Kidney Mitochondria DiabeticSTZ Rats. E.R. Esquivel-Gutiérrez, A. Saavedra-Molina, L.
Alcaraz-Meléndez. CIBNOR S.C., La Paz, BCS., Mexico and
UMSNH, Morelia, Mexico.
C273 1100.9 Hypoxic Adaptation by a Unique Mechanism of
Reprogramming Mitochondrial Metabolism. R.T. Tessman, H.
Chavan, G. Du, D. Sun, J. Schuetz, P. Krishnamurthy. Univ.
of Kansas Med. Ctr. and St. Jude Children’s Res. Hosp.
C274 1100.10 Avocado Oil Improves Renal Vasorelaxation in
Hypertensive Rats: Probable Role of Decreased Mitochondrial
ROS Generation and Enhanced Antioxidant Capacity. J.L.
Hernandez De La Paz, C. Marquez-Ramirez, R. Aguilar-Toral,
M. Moreno-Jimenez, A. Raya-Farias, R. Salgado-Garciglia,
D. Godinez-Hernandez, A. Saavedra-Molina, C. CortesRojo. Univ. Michoacana de San Nicolas de Hidalgo, Mexico.
C275 1100.11 Differential Effects of Diets Rich in Fats,
Carbohydrates And/or Fructose on the Development of
Hepatic Steatosis and Mitochondrial Dysfunction. C.I. GarciaBerumen, A. Alejandre-Buitron, R. Montoya-Perez, A.R.
Rodriguez-Orozco, E. Calderon-Cortes, R. Piña-Zentella, M.
Ramos-Gomez, A. Saavedra-Molina, C. Cortes-Rojo. Univ.
Michoacana of San Nicolas de Hidalgo and Autonomous Univ.
of Queretaro, Mexico.
C276 1100.12 Mitochondrial
Calcium
Entry
Induces
Mitochondrial Reactive Oxygen Species Production by ATP
Synthase-Uncoupled, but Proton Leak-Coupled Mechanism
– a New System of How Atherogenic Stimuli Activate Aortic
Endothelial Cells without Compromising Endothelial Cell
Survival. X. Li, H. Fu, P. Fang, W.J. Koch, H. Wang, X-F. Yang.
Temple Univ. Sch. of Med.
C277 1100.13 Avocado Oil Improves Mitochondrial Function
and Decreases Oxidative Stress in Kidney Mitochondria of
Type-2 Diabetic Rats. O. Ortiz-Avila, M. Figueroa-Garcia,
R. Mejia-Zepeda, F. Cabrera-Nuñez, C.G. Flores-Ledesma,
M.J. Hernandez-Esparza, A. Saavedra-Molina, C. CortesRojo. Univ. Michoacana de San Nicolas de Hidalgo and
UNAM, Tlalnepantla, Mexico.
C278 1100.14 Effects of Uric Acid and Melatonin Exposure
on Mitochondrial Complex-I Respiration, Triglyceride
Accumulation and Aconitase Activity in Skeletal Muscle Cells.
G.J. Maarman, B.M. Andrew, D. Blackhurst, E. Ojuka. Univ.
of Cape Town.
C279 1100.15 Insulin-Dependent
Glucose
Uptake
Is
Regulated by Mitochondrial Ca2+ Handling in Skeletal Muscle
Fibers. A.E. Contreras-Ferrat, A. Díaz-Vegas, C. Campos, Y.
Utreras, D. Valladares, G. Rosales, P. Llanos, M. Arias, E.
Jaimovich. Univ. de Chile.
C280 1100.16 Excitation-Metabolism Coupling: Role of
Membrane Depolarization on the Mitochondrial Function. A.
Díaz-Vegas, A. Cordova, Y. Utreras, G. Rosales, P. Llanos,
C. Hidalgo, M. Arias, E. Jaimovich, A.E. Contreras-Ferrat.
Univ. of Chile.
362
C281 1100.17 Caveolin-1 Regulates Mitochondrial Dynamics
by Suppressing Mfn-2 and Drp-1 Recruitment. Y. Jiang, P.
Toth, S. Oliveira, Y. Liu, P. Hart, J. Rehman, M. Bonini, R.D.
Minshall. Iniv. of Illinois at Chicago and Univ. of Electron. Sci.
and Technol. of China, Chengdu.
1101.NATURAL PRODUCT BIOSYNTHESIS FOR NEW
DRUG LEADS
Poster
Exhibit Halls A-D
C282 1101.1 Effect of Aqueous Leaf Extract of Pennisetum
purpurem in Alloxan-Induced Diabetic Wistar Rats. S.I.
Omeodu, B.M. Onyegeme-Okerenta. Univ. of Port
Harcourt, Nigeria.
C283 1101.2 The Biosynthesis of the Indolic Acid Moiety
from the Antibiotic Nosiheptide. E. Badding, S. Booker. Penns
State Univ. and HHMI.
C284 1101.3 Hypoglycaemic Activity of the Aqueous
Extract of Costus Afer Stems Alone and in Combination with
Metformin. C. Monago, F.C. Anacletus, T.K. Nwauche. Univ.
of Port Harcourt, Nigeria.
C285 1101.4 Quantification of Ethanolic Dandelion Root
Extract on the Growth Inhibition of Saccharomyces cerevisiae
H.M. Samuelson, T. Villari, R. Dunkley, F.M. Mann. Winona
State Univ.
C286 1101.5 Sub-acute Administration of Ethanol Extracts
of Erythrophloem suavolens Induced Hepatotoxicity and
Oxidative Stress in Wistar Strain Albino Rats. R.A. Adisa, C.U.
Nwalioba, S. Akujobi, J. Oribabor.
Univ. of Lagos, Nigeria and Univ. of Greenwich, U.K.
1102.INTERMICROBIAL INTERACTIONS
Poster
Exhibit Halls A-D
C287 1102.1 Interspecies Hydrogen Transfer and Its
Effects on Global Transcript Abundance in Ruminococcus
albus, a Predominant Fiber-Degrading Species in the Rumen.
R.R. Geier, I.H. Kwon, I.K. Cann, R.I. Mackie. Univ. of
Illinois, Urbana.
C288 1102.2 Investigating Mycobacteriohage-Host Protein
Interactions. A. Neevel, G. Chang, W. VandenBergh, V.
McDonough, J. Stukey. Hope Col., MI
TUESDAYBIOCHEMISTRY
1103.MICROBE-HOST INTERACTION
1105.MICROBIOME CHEMISTRY
Poster
Poster
Exhibit Halls A-D
Exhibit Halls A-D
C289 1103.1 The Role of Semen-Derived Exosomes
on Acute HIV Infection in T Lymphocytes. B. Moricz, M.N.
Madison, J. Welch, C. Okeoma. Lawrence Technol. Univ., MI
and Univ. of Iowa.
C290 1103.2 Mapping
Epitopes
of
Pan-Ebolavirus
Antibodies from Human Survivors. J.A. David, C.D. Murin, A.
Flyak, H.L. Turner, M.L. Fusco, E.O. Saphire, J.E. Crowe; Jr.,
A.B. Ward. The Scripps Res. Inst., Virginia Commonwealth
Univ., Vanderbilt Univ. and Vanderbilt Vaccine Ctr.
C291 1103.3 The Polyamine Pathway of Leishmania
donovani as a Potential Therapeutic Target. S. Roberts, D.
Paradis, J. Perdeh, J. Harrelson, B. Jan, P. Yates, B. Ullman.
Pacific Univ. and Oregon Hlth. & Sci. Univ.
C292 1103.4 Uncovering the Mechanism of Trogocytosis
in Entamoeba histolytica S.E. Feeney, K.S. Ralston. Univ. of
California, Davis.
C293 1103.5 Regulation of T Cell Activation by Herpes
Simplex Virus 1 Protein U. s3 S. Pan, S. Wu, Y. Liu, L. Zhang,
Q. Leng, D. Chen, M. Yang, J. Wang, B. He, C. Zhang, Y.
Cao. Sch. of Life Sci., Nankai Univ., China and Univ. of Illinois
at Chicago.
C294 1103.6 A Role for Underlying Glycan Structure in
Influenza Binding: Extending the Species Specificity Paradigm.
R.J. Woods, O.C. Grant, J.A. Hadden, H.M.K. Smith, W. Peng,
R. De Vries, R. McBride, J.C. Paulson. Univ. of Georgia, Natl.
Univ. of Ireland, Galway, Univ. of Illinois at Urbana-Champaign
and The Scripps Res. Inst.
C295 1103.7 Biological Activity of Outer Membrane Vesicles
from Clinical Isolates of Escherichia coli Y. Morales-Lozada,
G. Báez-Bravo, Y. Ferrer-Acosta, R. Gómez-Moreno, A.
Baerga-Ortiz. Univ. of Puerto Rico, Rio Piedras Campus and
Med. Sci. Campus.
1104.MICROBIAL ROLES IN DISEASE
Poster
Exhibit Halls A-D
C296 1104.1 Culture of Urine Sediment Reveals Differences
between Patients with Overactive Bladder (OAB) and Controls:
Are Changes in the Bladder Microbiome Responsible for
Symptoms of OAB? L. Krska, A. Balachandran, N. Caballero,
N. Curtiss, C. Peppiatt-Wildman, M. Strutt, J. Duckett, S.S.P.
Wildman. Medway Sch. of Pharm., Univ. of Kent, Medway
Maritime Hosp. and William Harvey Hosp., Ashford, U.K.
C297 1104.2 Determining Kinetics of Reversible and
Irreversible Biofilm Formation by Staphylococcus aur

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