UNIVERSITY OF MIAMI TISSUE BANK ALLOGRAFT TISSUE

Transcription

UNIVERSITY OF MIAMI TISSUE BANK
ALLOGRAFT TISSUE CATALOGUE
first in
Quality
first in
Service
1-888-684-7783
[email protected]
Table of Contents
Allograft Information………………………………………………………………………………………….3
General Information…………………………………………………………………………………….3
Statement from UMTB’s Medical Director ………………………………………………………………..4
University of Miami Tissue Bank (UMTB) ………………………………………………………………...4
Not for Profit Organization …………………………………………………………………………….6
Medical Personnel ……………………………………………………………………………………...6
Licenses and Accreditations …………………………………………………………………………..6
Laboratory Screening ………………………………………………………………………………………..7
Human Immunodeficiency Virus (HIV) ……………………………………………………………….7
Hepatitis B (HBV) and Hepatitis C Virus (HCV) ………………………………………………….....7
Human T Cell Lymphotrophic Virus I/II ………………………………………………………………7
Syphilis ………………………………………………………………………………………………….7
Tissue Preservation, Storage, Transit and Reconstitution ……………………………………………7
Fresh …………………………………………………………………………………………………….7
Fresh Frozen ……………………………………………………………………………………………8
Cryopreservation ……………………………………………………………………………………….9
Freeze Dried/ Lyophilized ……………………………………………………………………………10
General Orthopedics – Trauma and Reconstruction ……………………………………………...11-37
Radius…………………………………………………………………………………………………..11
Ulna……………………………………………………………………………………………………..12
Tibia Plate/Strut………………………………………………………………………………………..13
Proximal Tibia………………………………………………………………………………………….14
Tibia Segment/Tibia Shaft…………………………………………………………………………….15
Femur Condyle w/o Cartilage………………………………………………………………………...16
Distal Femur w/ Condyles .…………………………………………………………………………...17
Femur Head …………………………………………………………………………………………...18
Femur Plate (Strut) ……………………………………………………………………………………19
Proximal Femur ……………………………………………………………………………………….20
Femur Shafts & Segments …………………………………………………………………………...21
Fibular Shafts & Segments …………………………………………………………………………..22
Humerus Shafts & Segment………………………………………………………………………… 23
Proximal Humerus w/ Soft Tissue …………………………………………………………………..24
Cancellous Crushed 2-10mm………………………………………………………………………...25
Cancellous Cubes 4-10mm ………………………………………………………………………….26
Cancellous Powder 100-200m ………………………………………………………………………27
Cancellous Morselized 1-4mm……………………………………………………………………….28
Cortical Morselized 1-4mm....………………………………………………………………………...29
Cortical Cancellous Morselized ……………………………………………………………………..30
Cortical Powder 100-200m …………………………………………………………………………..31
Femur Head ……………………………………………………………………………………………32
Osteotomy Wedge …………………………………………………………………………………….33
Metacarpal ……………………………………………………………………………………………..34
Metatarsal ……………………………………………………………………………………………...35
Rib Cartilage …………………………………………………………………………………………..36
Fascia …………………………………………………………………………………………………..37
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Sports Medicine…………………………………………………………………………………………..38-50
Meniscus w/ Block …………………………………………………………………………………….38
Meniscus w/ Plateau ………………………………………………………………………………….39
Femur Condyle ………………………………………………………………………………………..40
Achilles …………………………………………………………………………………………………41
Anterior Tibialis Tendon ………………………………………………………………………………42
Posterior Tibialis Tendon …………………………………………………………………………….43
Peroneus Longus Tendon ……………………………………………………………………………44
Semitendinosus & Gracilis …………………………………………………………………………...45
Patellar Bone Tendon Bone – Half ………………………………………………………………….46
Patellar Bone Tendon Bone – Whole………………………………………………………………..47
Extensor & Flexor Tendon …………………………………………………………………………...48
Rotator Cuff ……………………………………………………………………………………………49
Spine – Neuro……………………………………………………………………………………………..50-56
Iliac Crest Strip ………………………………………………………………………………………..50
Fibula …………………………………………………………………………………………………...51
Iliac Crest Block ……………………………………………………………………………………….52
Iliac Crest Wedge ……………………………………………………………………………………..53
Bone Plug w/ Cortical End …………………………………………………………………………...54
Patella Wedge …………………………………………………………………………………………55
Dura Mater……………………………………………………………………………………………...56
OsteoArticular – Oncology Division Total Joints…………………………………………………..57-60
Elbow …………………………………………………………………………………………………...57
Distal Femur .…………………………………………………………………………………………..58
Hemipelvis ……………………………………………………………………………………………..59
Scapula ………………………………………………………………………………………………...60
Oral & Maxillofacial………………………………………………………………………………………61-63
Rib ………………………………………………………………………………………………………61
Mandible ……………………………………………………………………………………………….62
Mandibular & Maxilla (M&M) Blocks ………………………………………………………………..63
Fresh………………………………………………………………………………………………………..64-66
Femur Condyle ………………………………………………………………………………………..64
Meniscus w/ Plateau ………………………………………………………………………………….65
Ankle en Bloc & Talus…………………………………………………………………………………66
UMTB Safety Letter from Dr. H. Thomas Temple...…………………………………………………….67
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Allograft Information
General Information:
What is an allograft?
An allograft is soft tissue or bone that is removed from a human donor and used to surgically repair
damaged bones, joints and tendons. Over 1,000,000 allografts are implanted each year. In
orthopedics, an allograft is commonly used during ACL/PCL reconstructions, primary revision
knee/hip reconstruction and massive defects following tumor surgery.
Why is an allograft used?
Because of inadequate amounts of autograft (a person’s own bone or soft tissue) and the limited size
and shape of a person’s own bone, allograft is commonly used in reconstructive surgery of the hip,
knee and long bones, as well as in cases of bone loss due to trauma or tumors. Using allograft tissue
from another person will eliminate the need for a second operative site to remove autograft bone or
tendon, reduce the risk of infection at a separate surgical site, and safeguard against pain and loss of
function at or near the secondary site.
Where does an allograft come from?
A person has a choice regarding whether or not to donate their organs and tissues. These donors are
otherwise healthy people who have experienced a sudden illness or accident which ultimately led to
death.
What types of screening/safety measures are taken?
Before donation, all potential donors must undergo strict screening scrutiny that includes physical
examination, comprehensive medical history and social risk review. A detailed medical history that
includes social background and medical issues is obtained. The information collected on potential
donors is compared against criteria established by the United States Public Health Service to identify
and exclude individuals with high-risk behaviors. Furthermore, all tissue is held in quarantine until
microbiological and blood tests are completed. These tests are required by the American Association
of Tissue Banks (AATB) and the U.S. Food & Drug Administration (FDA) and include an analysis of
infectious diseases such as HIV, hepatitis B and C and syphilis. All of the information is evaluated by
a team of medical specialists in the fields of microbiology, orthopaedic surgery, pathology and tissue
banking. No allograft can be released until the tissue bank’s medical director determines the tissue to
be safe after review of the clinical and laboratory data.
How safe is an allograft?
Preparing the tissue for transplant begins with the removal of debris and organic matter. The allograft
is then soaked in various solutions to prevent the transmission of bacteria and viruses. Processing
and packaging are performed using aseptic techniques in clean room conditions to maintain biological
integrity. On occasion, low dose radiation is used to aid in sterilization. Final processed tissues are
tested for microbiological contamination in accordance with United States Pharmacopeia (USP)
guidelines to ensure compliance with regulatory requirements. Although there is a theoretical risk for
disease transmission, allograft transmitted infections are rare. The FDA has regulated this field very
closely since 1993 to ensure allograft transplant safety. Over the past decade, more than five million
musculoskeletal allografts have been distributed to surgeons for transplant into patients with a
remarkable record of safety.
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Statement from UMTB’s Medical Director
The University of Miami Tissue Bank is the first full-service civilian musculoskeletal tissue bank in the
United States. This not-for-profit organization is accredited by the American Association of Tissue
Banks and is registered with the Food and Drug Administration (FDA) it is licensed by State of Florida
Agency for Health Administration, the State of New York Department of Health, the State of California
Department of Health, the State of Maryland Department of Health, and the State of Delaware
Department of Health. The tissue bank performs the tissue procurement and performs processing in
accordance with existing professional standards and according to the FDA Good Manufacturing
Practice Guidelines (GMP) and Good Tissue Practices (GTP). A detailed outline of the donor
selection criteria and quality assurance procedures performed by the tissue bank in processing
allografts is described on the following pages.
H. Thomas Temple, MD
Director, Tissue Bank
Department of Orthopaedics
University of Miami Miller School of Medicine
University of Miami Tissue Bank (UMTB)
Transplantation of tissues touches the lives of many people in two ways; on one hand, it affects the
families of donors; on the other hand, it benefits the recipients. Transplanting bone into patients is
probably the most common form of transplantation today. The other most frequent is the
transplantation of corneas, skin and dura mater. Were it not for the understanding and generosity of
the nearest relatives of donors from whom the allografts were obtained, this would not be possible.
The advances in medical science and technology, plus the clinical experience gained during the last
few decades, allow for the increasing utilization of tissue transplants in surgery. To make this possible
and practical constitutes a major challenge, which requires the dedication of surgeons, pathologists,
nurses, microbiologists, technicians and other support personnel.
It also calls for a continuous effort on the part of researchers in both basic and applied sciences. The
present brochure describes briefly and in general terms the way in which the Tissue Bank and the
University of Miami Miller School of Medicine meet this challenge.
The University of Miami Tissue Bank was founded in 1970 as the U.S. Navy Tissue Bank curtailed its
service to civilian patients. These protocols and techniques were modified to keep pace with
technology and to improve safety. The technical personnel employed by the University of Miami
Tissue Bank during the first years of its operation were technicians trained by the U.S. Navy Tissue
Bank.
In its inception, bone and tissue allografts excised in Miami were freeze-dried by the U.S. Navy
Tissue Bank on a sharing basis. Tissue allografts preserved by freezing in mechanical freezers or in
the vapor phase of liquid nitrogen were processed locally. Since the activities of the Tissue Bank
have increased, the staff has expanded. So too has the scope of processing.
The past faculty members of the Department of Orthopaedics and Rehabilitation participate in the
activities of the Tissue Bank. Originally the Tissue Bank was housed in a three room operating room
suite and an office. Now the Tissue Bank has a separate, dedicated O.R. suite for procurement,
extensive aseptic processing rooms and other facilities used for the storage and preparation of
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human tissue allografts under optimal conditions. In the early years, the number of donors from whom
allografts were obtained varied from 20 to 40 yearly. The Tissue Bank now has over 500 multipletissue donors annually. It provides a full spectrum of services for the reconstructive surgery of the
musculoskeletal system and for skin banking.
In 1988, the University of Miami Tissue Bank acquired new facilities for the excision of tissues. A
specially designed operating room suite reserved exclusively for the excision of tissues for
transplantation was constructed in the Dr. Joseph H. Davis Center for Forensic Pathology. This was
made possible by a grant from the Rotary Foundation of Miami.
Currently the University of Miami Tissue Bank provides a wide range of services with emphasis on
allografts used for the reconstruction of the musculoskeletal system. The first massive osteoarticular
allograft prepared by the University of Miami Tissue Bank was transplanted in 1978; the first massive
intercalary allograft in 1974. To date, the Tissue Bank has supplied over 10,000 massive allografts
(osteoarticular, intercalary and structural prosthetic composite) to surgeons nationally and
internationally. Massive osteoarticular allografts are cryopreserved and stored in the vapor phase of
liquid nitrogen. Intercalary allografts are either quick-frozen or stored in the vapor phase of liquid
nitrogen or are freeze-dried. Frozen and freeze-dried allografts used for reconstructive procedures of
the axial skeleton as well as filling of smaller defects of bone and for arthrodesis have been supplied
to surgeons on a routine basis since 1972. Skin allografts have also been distributed since that time.
With few exceptions, all allografts distributed by the University of Miami Tissue Bank are excised and
processed aseptically. Allografts are prepared and processed in accordance with the U.S. Food and
Drug Administration’s regulations, as specified under Good Manufacturing Practices. In addition, the
Tissue Bank prepares other secondarily sterilized bone allografts when specifically requested by the
surgeon.
The possibility of transmission of disease with transplanted allografts has been a major concern to the
University of Miami Tissue Bank. This was heightened by the onset of the AIDS epidemic. To forestall
this possibility, the biology and epidemiology of HIV has been the subject of study by University of
Miami researchers. Some of these findings resulted in recommendations for quality control measures
adopted by SEOPF and by the American Academy of Orthopaedic Surgeons.
In an effort to improve the quality of life and to make transplants readily available to patients, the
University of Miami Tissue Bank has assisted in the organization of new tissue banks in the United
States and abroad. It has also provided training for personnel from other tissue banks from the U.S.
and foreign countries and for surgeons interested in bone transplantation and tissue banking.
Staff members of the University of Miami Tissue Bank have been particularly active in the clinical
application of bone allografts in the reconstruction of failed total hip arthroplasties, reconstruction of
the extremities following resection of tumors and in spinal surgery. As a result, the University of Miami
has one of the largest orthopaedic oncology services in the world. In addition, transplantation of dura
mater allografts for the closure of pachymeningeal defects has been primarily developed at this
institution. The personnel of the Tissue Bank can view the accomplishments of the Tissue Bank with
pride. These have been achieved only through the participation and collaboration of personnel on all
levels. We look forward to the continuation of our activities and service to patients.
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Not for Profit Organization
The University of Miami Tissue Bank has not, does not and will not engage in the sale of human
tissue. The sale of human tissue for financial compensation is illegal under Public Law 98-507, s.301;
42 United States Code s.274e; and Chapter 873, F.S. 59A1.005(11), F.A.C. The fees imposed on the
recipients of allografts are for the recovery of direct expenses associated with the excision,
preparation, storage, distribution and quality assurance studies of allografts. Financial records are
audited periodically in keeping with University of Miami and State of Florida policies.
Medical personnel fully trained in tissue banking and tissue transplantation:
•
H. Thomas Temple, M.D. (Director Tissue Bank, Department of Orthopaedics,
University of Miami Miller School of Medicine)
•
Theodore I. Malinin, M.D. (Research, Tissue Bank, Department of Orthopaedics,
•
Bill B. Buck, M.D. (Associate Director, Tissue Bank, Department of Orthopaedics,
•
Paul Morris, M.D. (Associate Director, Tissue Bank, Department of Orthopaedics,
•
Octavio V. Martinez, Ph.D. (Director, Microbiology Laboratory, Tissue Bank, Department
of Orthopaedics, University of Miami Miller School of Medicine)
All of the tissue bank physicians constitute the Medical Review Board.
Safety and quality is the University of Miami Tissue Bank’s first priority
•
Not-for-profit organization
•
The first civilian (spin off from the U.S. Navy tissue bank) tissue bank in the industry
•
Multifunctional tissue bank
•
Performs the tissue excision and processing
•
Operational procedures exceeds AATB and FDA standards
•
Surgeon-to-surgeon consultations available
•
Physician participation in donor screening, prior to recovery, processing, and distribution
•
Post mortem examinations (autopsy) on all donors
•
Allograft transplantation by University of Miami School of Medicine surgeons serves as
internal quality control
•
Follows Good Tissue Practices and Good Manufacturing Practice Guidelines
•
State of the art testing
•
Physicians (directors of the tissue bank) evaluate all information including tests results
before release of tissue for clinical use.
Licenses and Accreditations
•
Accredited by the American Association of Tissue Banks
•
Registered with the Food and Drug Administration
•
Certified by the State of Florida Agency for Health Care Administration
•
Licensed by the State of New York Department of Health
•
Licensed by the State of California Department of Health
•
Permitted by the State of Maryland Agency for Health Care Administration
•
Licensed by the State of Delaware Department of Health & Safety
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Tracking of the Donor
The University of Miami Tissue Bank’s records management system:
•
Permits tracing of a tissue from the donor to the consignee and from the consignee to
the donor
•
Permits donor identification of a tissue at any phase of the operation
•
Indicates the dates and staff involved in each significant step of the operation from the
time of retrieval through final disposition of the tissue as well as the tissue identification
number(s)
•
Allows for laboratory and QC specimens related to a donor or tissue to be traceable to
the donor
Laboratory Screening
The following mandatory tests are performed using approved methods by a certified laboratory:
Tissues shall not be released for transplantation if blood results are reactive.
The blood and/or tissue(s) of the donors were tested for/by the following and all the tests were found
to be negative.
TEST
SYMBOL
-Human Immunodeficiency Virus (HIV)
HIV-1/2 Antibodies
HIV-1/2-Ab
Nucleic Acid Test for HIV-1 RNA
HIV-1 NAT
-Hepatitis B Virus (HBV)
HBV Surface Antigen
HBsAg
HBV Core Antibody (IgG & IgM)
HBcAb
Nucleic Acid Test for HBV DNA (if applicable) HBV NAT
-Hepatitis C Virus (HCV)
HCV Antibody
HCVAb
Nucleic Acid Test for HCV RNA
HCV NAT
-Human T Cell Lymphotrophic Virus I/II (if applicable)
HTLV-I/II Antibody
HTLV-I/II-Ab
-Syphilis – Rapid Plasma Reagin Screen
RPR*
Or
T. Pallidum IgG
T. pallidum IgG
Tissue Preservation, Storage, Transit and Reconstitution
Fresh (Refrigerated Temperature)
Allografts:
Femoral condyles, talus, patella, humerus head
Preservation:
Simple hypothermia is the storage of tissues at or about 1 ˚C to 10˚C that are usually immersed in
nutrient culture media (examples: RPMI 1640- Roswell Park Memorial Institute, LR-Lactated Ringers,
etc.) with antibiotics. This method of preservation is used for short-term storage only and is intended
to preserve viable cells. The limitations of this preservation technique are evident in the short shelf-life
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of the tissue graft. Hypothermia reduces the oxygen consumption of the viable cells, thereby slowing
cellular metabolism and allowing the recovery of the maximum number of viable cells.
Storage:
The individual allografts are submerged in nutrient culture media with antibiotics. Upon arrival,
allograft should have the appearance of floating in solution. If the liquid appears frozen, the graft
should be treated as useless to its application. The cells have died and are not viable. The sterile
packaging may be in plastic jars or pouches. Whatever the packaging, it is always sterile and in
twofold. The circulator handles the outer packaging while handing the inner container to the scrubbed
personnel.
Transit:
Pre-frozen foam refrigerant (ice packs/blue ice/wet ice) is packed around the fresh tissue in wellinsulated styrofoam boxes. Upon arrival to the hospital, if surgery is not immediate, remove allograft
contained in its packaging from styrofoam box and place in the refrigerator compartment (not freezer!)
until surgery.
Reconstitution:
Suitable thawing procedures for the fresh allograft, submerge into refrigerated 1˚C to 10˚C sterile
lactated ringer’s bath with or without antibiotics. From recovery, processing, storage and shipment,
the allograft has been kept at hypothermia. It is logical to reconstitute the graft in solutions at that
temperature.
Fresh Frozen
Allografts:
Bone-Patellar Tendon-Bone, Achilles Tendon with Bone Strut (Calcaneous), Semitendinosus/Gracilis
Tendons, Tibialis Tendon, Peroneous Longus Tendon
Preservation:
The freezing of tissues at temperatures below -70˚C is routinely used for the long-term storage of
musculoskeletal tissues. Storage at these temperatures is thought to inhibit enzymatic degradation of
tissues, most notably collagenase and protease activity. An uncontrolled freeze of tissues at these
temperatures does not aid in the preservation of viable cells; therefore, this technique is reserved for
tissues in which cellular viability is not crucial to the clinical performance of the allografts. Many
mechanical refrigeration devices are capable of attaining these temperatures. In addition, liquid
nitrogen storage containers are quite suitable for the storage of these tissues, attaining temperatures
as low as -196˚C.
Storage:
The individual allografts are frozen with little or no solution. The sterile packaging may be in plastic
jars or pouches. Whatever the packaging, it is always aseptic and in twofold. The circulator handles
the outer packaging while handing the inner container to the scrubbed personnel.
Transit:
Dry ice packed around the frozen tissue in well-insulated styrofoam or similar boxes has proven
effective for maintaining frozen bone during transport to the user institution. Dry Ice (solid carbon
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dioxide, temperatures about -76˚C) is acceptable for storage. The only drawback is that it is a
logistical problem of checking the quantity levels of dry ice and restocking on a daily basis, depending
on the size of the container. For suppliers of dry ice in your area—most supermarkets carry dry ice for
sale or their own storage use—check the yellow pages under dry ice or carbonics. Standard
mechanical freezers were manufactured to mimic the temperatures of dry ice to reduce logistical
problems. However, for reliable long-term storage, it is necessary to reduce the temperature further.
Cryopreservation
Allografts:
Distal Femurs, Proximal Tibias, Meniscal grafts, Hemipelvis, Proximal Humerus
Preservation:
Cryopreservation is the freezing of tissues at a controlled rate, usually 1 to 2 ˚C per minute, in the
presence of a cryoprotectant solution (glycerol). This method is intended to preserve viable cells
when their viability is thought to play an important role in the success of the allograft. Accurate
controlled-rate freezing is usually computer controlled, with liquid nitrogen vapor as the coolant.
Subsequent storage of these cryopreserved tissues is usually at liquid nitrogen vapor phase
temperatures.
Storage:
The individual allografts are frozen with little or no solution. The sterile packaging is in plastic
pouches and is always sterile and in twofold. The circulator handles the outer packaging while
handing the inner container to the scrubbed personnel.
Transit:
Dry ice packed around the cryopreserved frozen tissue in well-insulated styrofoam or similar boxes
has proven effective for maintaining frozen bone during transport to the user institution. Dry Ice (solid
carbon dioxide, temperatures about -76˚C) is acceptable for storage. The only drawback is that it is a
logistical problem of checking the quantity levels of dry ice and restocking on a daily basis, depending
on the size of the container. For suppliers of dry ice in your area—most supermarkets carry dry ice for
sale or their own storage use—check the yellow pages under dry ice or carbonics. Standard
mechanical freezers were manufactured to mimic the temperatures of dry ice to reduce logistical
problems. However, for reliable long-term storage, it is necessary to reduce the temperature still
further.
Liquid nitrogen:
Only at about -120˚C does gradual growth of ice crystals completely cease.
Liquid nitrogen provides a range of cryogenic temperatures. A property of major importance in liquid
nitrogen is its chemical inertness. Unlike carbon dioxide or other solvents used, it does not react with
the materials with which it comes in contact. It has no effect on the pH of frozen tissue and vaporizes
without leaving a residue. Temperatures range from -130˚C to -196˚C. Tissues should be placed in
the vapor phase above liquid nitrogen because the packaging of allograft may not withstand the
incredibly ultra cold characteristic of the liquid.
Reconstitution: Suitable thawing procedures
Submerge the cryopreserved frozen allograft into a 22-37˚C sterile lactated ringer or similar solution
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with or without antibiotics.
Note: Overly heated solutions will denature the tissues and render them useless.
Short Term Storage—Frozen Graft
Storage of bone in conventional freezers (about -20˚C) is popular because it requires only easily
obtainable, generally available freezers. However, at this temperature ice crystals grow and
eventually destroy the bone. In addition to a mechanical disruption by ice crystals, injury from freezing
is caused by factors which may include dehydration, metabolic aberrations resulting from storage at
temperatures at which some enzymes may continue to function and direct chemical injury.
Freeze Dried / Lyophilized
Preservation:
Freeze-drying is the removal of water from a substance under vacuum, transforming the water in its
crystalline form to water vapor without its ever passing through the liquid phase. This phenomenon is
termed sublimation. This means of preserving tissue was first implemented by the U.S. Navy Tissue
Bank. Lyophilization is quite useful in the long-term preservation and storage tissues when other
means are impractical. Once tissue is freeze-dried, it can be maintained at room temperatures
without the need for special handling and can be distributed over long distances. Freeze drying is
purported to alter the biomechanical properties of tissues; therefore, rehydration of the tissue prior to
use is required to restore these properties.
Storage:
The individual allografts packaging may be in glass jars or plastic pouches. Whatever the packaging,
it is always aseptic. The circulator handles the outer packaging while handing the inner container to
the scrubbed personnel.
Transit:
Freeze dried tissue is placed to avoid breakage and is shipped at ambient temperatures.
Reconstitution: Suitable thawing procedures
Submerge the freeze-dried allograft into a 22 ˚C–37˚C sterile saline baths (0.9% sodium chloride) with
or without antibiotics. This should be done as the surgery is beginning. By the time the surgical site is
prepared to receive the allograft, the tissue will be thawed.
Note: Overly heated solutions will denature the tissues and render them useless.
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General Orthopedics – Trauma and Reconstruction
RADIUS
Product Code
Product Description
Preservation
Sterilization
Category
0363
1181
0729
1817
Radius Segment
Radius Segment
Radius Shaft
Radius Shaft
Freeze Dried
Fresh Frozen
Freeze Dried
Fresh Frozen
Aseptic
Aseptic
Aseptic
Aseptic
Base Bone
Base Bone
Base Bone
Base Bone
Common Graft Utilization:
Tumor Resection, Fracture Management, Spine
Features / Benefits:
Segment: < 15cm
Shaft: > 15cm
 The University of Miami Tissue Bank (UMTB) has distributed tissue for transplantation for over 40
years. Since 1970, there have been no reports or observations of disease transmission.
 UMTB’s aseptic processing technique provides a minimally manipulated allograft which does not affect
the biomechanical or osteoinductive properties of the tissue – the closest to an autograft.
 All data has been reviewed by a Medical Director or Associate Medical Director (licensed physician)
and the allograft has been deemed suitable for transplantation.
Page 12 of 68
ULNA
Product Code
Product Description
Preservation
Sterilization
Category
0165
Ulna Segment
Freeze Dried
Aseptic
Base Bone
1239
Ulna Shaft
Freeze Dried
Aseptic
Base Bone
Tumor Resection, Fracture Management, Total Joint Augmentation
Segment: L < 15cm
Shaft: L > 15cm
Page 13 of 68
TIBIA PLATE/STRUT
Product Code
Product Description
Preservation
Sterilization
Category
0723
Tibia Plate Small <15cm
Tibia Plate Medium
≥15cm <20cm
Freeze Dried
Aseptic
Base Bone
Freeze Dried
Aseptic
Base Bone
Tibia Plate Large ≥20cm
Freeze Dried
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Freeze Dried
Aseptic
Base Bone
0139
0509
0321
0520
1898
Tibia Plate Medium
≥15cm <20cm
Tibia Plate Large ≥20cm
Tibia Plate Flat
W = 2.2 - 2.7cm, L = 14.9 - 18cm
Tumor Resection, Fracture Management
Tibia Plate Flat width and thickness is consistent throughout graft.
Page 14 of 68
PROXIMAL TIBIA
Product Code
Product Description
Preservation
Sterilization
Category
0084
Distal Tibia – Left
Cryopreserved
Aseptic
OsteoArticular
0083
Distal Tibia – Right
Proximal Tibia w/
Patella - Right
Proximal Tibia w/
Patella – Left
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoAritcular
0188
0189
Tumor Resection, Fracture Management, Joint Replacement
Key Features & Benefits:
Sizes may be patient matched
Page 15 of 68
TIBIA SEGMENT/TIBIA SHAFT
Product Code
0073
0074
0448
0011
Product Description
Tibia Segment <15cm
Tibia Shaft ≥15cm
Tibia Segment <15cm
Tibia Shaft ≥15cm
Preservation
Freeze Dried
Freeze Dried
Fresh Frozen
Fresh Frozen
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Category
Base Bone
Base Bone
Base Bone
Base Bone
Tumor Resection, Fracture Management, Total Joint Augmentation
Multiple lengths available
Page 16 of 68
FEMUR CONDYLE W/O CARTILAGE
Product Code
Product Description
Preservation
Sterilization
Category
0067
Femur Condyle Hemi
Femur Condyle
Lateral
Femur Condyle
Medial
Freeze Dried
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
0417
0418
Tumor Resection, Trauma Cases, Joint Arthroplasty, Fracture Management, Filling Osseous
Defects/Voids
Page 17 of 68
DISTAL FEMUR W/ CONDYLES
Product Code
Product Description
Preservation
Sterilization
Category
0144
Distal Femur - Left
Fresh Frozen
Aseptic
Base Bone
0124
Distal Femur - Right
Distal Femur w/ ligaments Left
Distal Femur w/ ligaments Right
Fresh Frozen
Aseptic
Base Bone
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoArticular
0082
0081
Tumor Resection, Fracture Management, Joint Revision & Replacement
Shaft L = 15cm
Page 18 of 68
FEMUR HEAD
Product Code
Product Description
Preservation
Sterilization
Category
0039
0495
0038
1290
Femur Head
Femur Head
Femur Head
Femur Head
Freeze Dried
Freeze Dried
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Aseptic
Irradiated
Base Bone
Base Bone
Base Bone
Base Bone
Total Hip Revisions and Osteoplasties, Tumor Resection, Joint Arthroplasty, Fracture Management,
Filling Osseous Defects/Voids,
Various sizes available
Page 19 of 68
FEMUR PLATE (STRUT)
Product Code
0138
0191
0519
0522
Product Description
Femur Plate Medium
≥ 15cm <20cm
Femur Plate Medium
≥ 15cm <20cm
Femur Plate Large
≥ 20cm
Femur Plate Large ≥
20cm
Preservation
Sterilization
Category
Freeze Dried
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Freeze Dried
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Page 20 of 68
PROXIMAL FEMUR
Product Code
0449
0726
0730
0248
Product Description
Proximal Femur w/Head Left
Proximal Femur w/ Head –
Right
Proximal Femur w/
Ligaments - Left
Proximal Femur w/
Ligaments - Right
Preservation
Sterilization
Category
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoArticular
Fresh Frozen
Aseptic
Base Bone
Fresh Frozen
Aseptic
Base Bone
Tumor Resection, Fracture Management, Joint Revision
Various sizes available
May be patient matched
Page 21 of 68
FEMUR SHAFTS & SEGMENTS
Product Code
Product Description
Preservation
Sterilization
Category
0035
0037
0034
0036
Femur Segment <15cm
Femur Shaft ≥15cm
Femur Segment <15cm
Femur Shaft ≥15cm
Freeze Dried
Freeze Dried
Fresh Frozen
Fresh Frozen
Aseptic
Aseptic
Aseptic
Aseptic
Base Bone
Base Bone
Base Bone
Base Bone
Page 22 of 68
FIBULA SHAFTS & SEGMENTS
Product Code
3029
3029r
0047
0486
3030
3030r
0049
0048
Product Description
Fibula Segment 2.0 – 4.9cm
Fibula Shaft ≥15cm
Fibula Shaft ≥15cm
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Fresh Frozen
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Aseptic
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Tumor Resection, Fracture Management, Spine Surgery
Page 23 of 68
HUMERUS SHAFTS & SEGMENTS
Product Code
Product Description
Preservation
Sterilization
Category
0050
0052
Humerus Segment
Humerus Shaft
Freeze Dried
Freeze Dried
Aseptic
Aseptic
Base Bone
Base Bone
0053
Humerus Shaft
Fresh Frozen
Aseptic
Base Bone
Segment: L <15cm
Shaft: L > 15cm
Page 24 of 68
PROXIMAL HUMERUS W/ SOFT TISSUE
Product Code
1799
1497
1800
1498
0095
0094
0098
0099
Product Description
Proximal Humerus w/
Ligaments – Left
Proximal Humerus – Left
Proximal Humerus w/
Ligaments - Right
Proximal Humerus - Right
Proximal Humerus w/ Head
& Ligaments – Left
Proximal Humerus w/ Head
& Ligaments - Right
Whole Humerus – Left
Whole Humerus – Right
Preservation
Sterilization
Category
Fresh Frozen
Aseptic
Base Bone
Fresh Frozen
Irradiated
Base Bone
Fresh Frozen
Aseptic
Base Bone
Fresh Frozen
Irradiated
Base Bone
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Cyropreserved
Aseptic
Aseptic
OsteoArticular
OsteoArticular
Tumor Resection, Fracture Management, Total Joint Replacement
Total L= ≥15cm
The rotator cuff and surrounding tissue attachments are L = min 2cm
Page 25 of 68
CANCELLOUS CRUSHED 2-10MM
Product Code
1612
1615
0033
1500
1404
1592
0545
1383
1405
1481
0027
1499
Product Description
Cancellous Crushed 05cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Spinal Fusion, Space Filling, Sinus Augmentation
Fresh Frozen may be stocked upon request
Larger volume may be stocked upon request
Page 26 of 68
CANCELLOUS CUBES 4-10MM
Product Code
1521
1625
0580
1136
0560
1545
0567
0488
0559
1549
0566
0485
Product Description
Cancellous Cubes 05cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Page 27 of 68
CANCELLOUS POWDER 100-200M
Product Code
3013
3013r
1454
1628
1455
1667
1456
1704
Product Description
Cancellous Powder 05cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Page 28 of 68
CANCELLOUS MORSELIZED 1-4MM
Product Code
3039
3039r
0847
1133
1842
1783
0691
1134
1843
1844
0690
1135
Product Description
Cancellous Morselized 05cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Space filling
Larger sizes may be stocked upon request.
Page 29 of 68
CORTICAL MORSELIZED 1-4MM
Product Code
0505
1744
0692
1145
0409
1146
Product Description
Cortical Morselized 10cc
Coritcal Morselized 10cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Space filing
Page 30 of 68
CORTICAL CANCELLOUS MORSELIZED 1-4MM
Product Code
1258
1376
1257
1377
1256
1378
Product Description
Cortical Cancellous Morselized 30cc
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Space filing
Page 31 of 68
CORTICAL POWDER 100-200m
Product Code
Product Description
Preservation
Sterilization
Category
1631
1458
1138
1459
1139
1460
1140
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Particulate
Page 32 of 68
FEMUR HEAD
Product Code
Product Description
Preservation
Sterilization
Category
1493
0707
Femur Head - Left
Femur Head - Right
Cryopreserved
Cryopreserved
Aseptic
Aseptic
OsteoArticular
OsteoArticular
Cartilage Replacement, Articular Resurfacing
Page 33 of 68
OSTEOTOMY WEDGE
Product Code
Product Description
Preservation
Sterilization
Category
0809
1178
0779
1177
Osteotomy Wedge (2 Piece)
Osteotomy Wedge (2 Piece)
Osteotomy Wedge
Osteotomy Wedge
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Aseptic
Irradiated
Base Bone
Base Bone
Base Bone
Base Bone
High Tibial Osteotomy
2 per package: W = min 2cm X L = 5cm X H = min 1.75cm
1 per package: W = min 3cm X L = 6cm X H = min 1.75cm
Page 34 of 68
METACARPAL
Product Code
0360
0410
0228
0225
0229
0226
0230
0227
0231
0232
Product Description
Metacarpal/Phalanx #1- Left
Metacarpal/Phalanx #1 –Right
Metacarpal/Phalanx #2 - Left
Metacarpal/Phalanx #2 - Right
Metacarpal/Phalanx #3 –Left
Metacarpal/Phalanx #3 – Right
Metacarpal/Phalanx #4 – Left
Metacarpal/Phalanx #5 – Left
Preservation
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Category
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
Joint replacement, Trauma
Features /Benefits:
Page 35 of 68
METARSAL
Product Code
Product Description
Preservation
Sterilization
Category
0462
0461
0539
0538
0540
0240
0541
0241
0696
0242
Metatarsal #1 – Left
Metatarsal #1 – Right
Metatarsal #2 - Left
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
OsteoArticular
OsteoAritcular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
Tumor resection, Joint replacement, Trauma
Page 36 of 68
RIB CARTILAGE
Product Code
Product Description
Preservation
Sterilization
Category
0155
1518
0160
1420
Rib Cartilage
Rib Cartilage
Rib Cartilage
Rib Cartilage
Freeze Dried
Freeze Dried
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Aseptic
Irradiated
Base Bone
Base Bone
Base Bone
Base Bone
Plastic Surgery, Reconstructive Surgery
L > min 3cm
W = min 1cm
Various lengths and widths
Page 37 of 68
FASCIA
Product Code
0006
0428
0716
0759
1194
0763
0154
1317
1316
1827
Product Description
Fascia Lata
Fascia Lata
Fascia Lata – Patch
Fascia Lata – Sling
Fascia Lata – Sling
Fascia Lata – Strip
Fascia Lata
Fascia Lata
Fascia Lata - Sling
UM Fanfold Fascia
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Sterilization
Aseptic
Irradiated
Aseptic
Aseptic
Irradiated
Aseptic
Aseptic
Irradiated
Irradiated
Aseptic
Category
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Soft Tissue
Pubovaginal Sling/Urinary Stress Incontinence, Periodontal and Ridge Defects, Membrane Barrier
when primary closure cannot be obtained
Patch: 20cm2 or 4cm x 5cm; Sling: W≥4.0cm, L = min 15cm; Strip: W = 0.5cm - 1.0 cm, L= min 20cm;
Large Freeze Dried: W = min 8.0cm, L = min 18cm; Large Frozen: W = min. 10 cm, L = min 20cm
 Large graft: W=10cm L=20cm The University of Miami Tissue Bank (UMTB) has distributed tissue
for transplantation for over 40 years. Since 1970, there have been no reports or observations of
disease transmission.
Page 38 of 68
Sports Medicine
MENISCUS W/ BLOCK
Product Code
0775
0781
0818
0808
1555
1559
1554
1558
1553
1557
1552
1556
Product Description
Meniscus Medial w/ Block – Left
Meniscus Medial w/ Block – Right
Meniscus Lateral w/ Block – Left
Meniscus Lateral w/ Block – Right
Meniscus Lateral w/ Block - Left
Meniscus Lateral w/ Block – Left
Meniscus Medial w/ Block – Right
Meniscus Medial w/ Block –Right
Preservation Sterilization
Cryopreserved
Aseptic
Cryopreserved
Aseptic
Cryopreserved
Aseptic
Cryopreserved
Aseptic
Fresh Frozen
Aseptic
Fresh Frozen
Irradiated
Fresh Frozen
Aseptic
Fresh Frozen
Irradiated
Fresh Frozen
Aseptic
Fresh Frozen
Irradiated
Fresh Frozen
Aseptic
Fresh Frozen
Irradiated
Category
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Meniscus Replacement, Glenoid Resurfacing
LB = Length of Bone Block, measured at widest point
TB = Thickness of Bone Block; min 1.5cm
WB = Width of Bone Block, measured at widest point
Page 39 of 68
Sports Medicine
MENISCUS W/ PLATEAU
Product Code
0193
0126
0427
1632
1581
1644
Product Description
Meniscus w/ Plateau – Left
Meniscus w/ Plateau – Right
Preservation
Cryopreserved
Cryopreserved
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Sterilization
Aseptic
Aseptic
Aseptic
Irradiated
Aseptic
Irradiated
Category
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Meniscus Replacement, Glenoid Resurfacing
Whole available
Page 40 of 68
Sports Medicine
FEMUR CONDYLE
Product Code
0440
0439
0728
0704
0727
0423
Product Description
Whole Femur Condyle – Left
Whole Femur Condyle – Right
Lateral Femur Condyle – Left
Lateral Femur Condyle – Right
Medial Femur Condyle – Left
Medial Femur Condyle - Right
Preservation
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Category
OsteoArticulatar
OsteoArticulatar
OsteoArticulatar
OsteoArticulatar
OsteoArticulatar
OsteoArticulatar
Page 41 of 68
Sports Medicine
ACHILLES
Product Code
Product Description
Preservation
Sterilization
Category
0009
0765
1288
1532
Achilles Tendon w/ Bone Block
Achilles Tendon w/ Bone Block
Achilles Tendon w/o Bone Block
Achilles Tendon w/o Bone Block
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Aseptic
Irradiated
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Anterior/posterior cruciate ligament replacement, Reconstruction, Extensor Mechanism Replacement
Available in variable dimensions. Call UMTB for sizes
Bone Block L = min 25mm
Tendon L ≥ 200 mm
LB = Length of Bone Block
WB = Width of Bone Block
LT =Length of Tendon
WT = Width of Tendon
Page 42 of 68
Sports Medicine
ANTERIOR TIBIALIS TENDON
Product Code
Product Description
Preservation
Sterilization
Category
0332
1198
Anterior Tibialis Tendon
Anterior Tibialis Tendon
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Sports Medicine
Sports Medicine
Anterior/Posterior Cruciate Ligament Replacement and Reconstruction, Tendon Repair
Call UMTB for sizes
D = Double Loop; W ≥ 7mm
DL measured in linear < 7mm
L = min 240mm
Page 43 of 68
Sports Medicine
POSTERIOR TIBIALIS TENDON
Product Code
0333
1199
Product Description
Posterior Tibialis Tendon
Posterior Tibialis Tendon
Preservation
Fresh Frozen
Fresh Frozen
Sterilization
Aseptic
Irradiated
Category
Sports Medicine
Sports Medicine
Anterior/Posterior Cruciate Ligament Replacement and Reconstruction, Tendon Repair, Rotator Cuff
Repair
Call UMTB for sizes
L = min 240mm
DL measured in linear; W < 7mm
Page 44 of 68
Sports Medicine
PERONEUS LONGUS TENDON
Product Code
Product Description
Preservation
Sterilization
Category
0336
1201
Peroneus Longus Tendon
Peroneus Longus Tendon
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Sports Medicine
Sports Medicine
Call UMTB for sizes
L = min 240mm
Page 45 of 68
Sports Medicine
SEMITENDINOSUS & GRACILIS
Product Code
Product Description
Preservation
Sterilization
Category
1746
1748
Gracilis Tendon
Gracilis Tendon
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Sports Medicine
Sports Medicine
1745
1747
0783
1200
SemiT Tendon
SemiT Tendon
SemiT Gracilis Tendon
SemiT Gracilis Tendon
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Aseptic
Irradiated
Aseptic
Irradiated
Sports Medicine
Sports Medicine
Sports Medicine
Sports Medicine
Call UMTB for sizes
L = min 240mm
LG = Length of Gracilis
LST =Length of SemiTendinosus
Page 46 of 68
Sports Medicine
PATELLAR BONE TENDON BONE – HALF
Product Code
0008
0414
Product Description
Patella Tendon w/ Bone Block
- Half
Patella Tendon w/ Bone Block
- Half
Preservation
Sterilization
Category
Fresh Frozen
Aseptic
Sports Medicine
Fresh Frozen
Irradiated
Sports Medicine
Anterior/posterior cruciate ligament replacement and reconstruction and extensor mechanism
replacement
Bone Block tibia tubercle; L = min 20mm, W = min 12mm
LP = Length of patella
LPL = Length of patella ligament
LTS = Length of tibia bone
LQT = Length of quad tendon
WT = Width of tendon
WB = Width of bone
TB = Thickness of bone
Page 47 of 68
Sports Medicine
PATELLAR BONE TENDON BONE - WHOLE
Product Code
0264
0766
0263
0550
Product Description
Patella Tendon w/ Bone Block –
Left
Left
Right
Right
Preservation
Sterilization
Category
Fresh Frozen
Aseptic
Sports Medicine
Fresh Frozen
Irradiated
Sports Medicine
Fresh Frozen
Aseptic
Sports Medicine
Fresh Frozen
Irradiated
Sports Medicine
Anterior/Post Cruciate Ligament Replacement/Reconstruction, Extensor Mechanism Replacement
Bone Block: L = min 25mm, W ≥ 10 mm
LP = Length of patella
LPL = Length of patella ligament
LPB = Length of tibia bone
LQT = Length of quad tendon
WT = Width of tendon
WB = Width of bone
TB = Thickness of bone
WC = Width of Patella
Page 48 of 68
Sports Medicine
EXTENSOR & FLEXOR TENDON
Product Code
0799
Product Description
Extensor Tendon (Arm)
Preservation
Cryopreserved
Sterilization
Aseptic
Category
Sports Medicine
0800
Flexor Tendon (Arm)
Cryopreserved
Aseptic
Sports Medicine
Call UMTB for sizes
Page 49 of 68
Sports Medicine
ROTATOR CUFF
Product Code
Product Description
Preservation
Sterilization
Category
0014
Rotator Cuff
Fresh Frozen
Aseptic
Sports Medicine
Rotator Cuff Repair
Call UMTB for sizes
Rotator W = min 2cm
Page 50 of 68
Spine - Neuro
ILIAC CREST STRIP
Product Code
Product Description
Preservation
Sterilization
Category
0055
1189
0473
1190
0056
1191
Iliac Crest Strip Small
Iliac Crest Strip Small
Iliac Crest Strip Medium
Iliac Crest Strip Medium
Iliac Crest Strip Large
Iliac Crest Strip Large
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Spinal Surgery
Small: W < 70mm
Medium: W= 70-90mm
Large: W > 90mm
Page 51 of 68
Spine – Neuro
FIBULA
Product Code
3029
3029r
0047
0486
3030
3030r
0049
Product Description
Fibular Segment 2cm – 4.9cm
Fibular Segment 2cm – 4.9cm
Fibula Segment 5cm – 9.9cm
Fibula Shaft ≥ 15cm
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Anterior Cervical Fusion
Page 52 of 68
Spine – Neuro
ILIAC CREST BLOCK
Product Code
0064
0499
Product Description
Iliac Crest Block
Iliac Crest Block
Preservation
Sterilization
Category
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Base Bone
Base Bone
Spinal Fusion, Tibial Wedge Osteotomy, Ankle Fusion
L = 7 cm
W = min 2cm
Page 53 of 68
Spine - Neuro
ILIAC CREST WEDGE
Product Code
1329
1329r
1330
1330r
1331
1331r
1332
1332r
1333
1333r
0054
0497
0848
1192
1250
1328
Product Description
Iliac Crest Wedge 6mm x 12mm
Iliac Crest Wedge
Iliac Crest Wedge
Iliac Crest Wedge – Lumbar Fusion
Iliac Crest Wedge - Lumbar Fusion
*Thick Tricortical Wedge
*Thick Tricortical Wedge
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiate
Aseptic
Irradiated
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Spinal Surgery
Various Sizes Available
* W > 2cm, H > 2cm, L > 2.5cm
Page 54 of 68
Spine – Neuro
BONE PLUG W/ CORTICAL END
Product Code
1243
1639
0527
1149
0023
1150
0683
1153
0024
0489
0025
0490
0266
1151
Product Description
Bone Plug 8mm
Bone Plug 8mm
Bone Plug 10mm
Bone Plug 10mm
Bone Plug 12mm
Bone Plug 12mm
Bone Plug 13mm
Bone Plug 13mm
Bone Plug 14mm
Bone Plug 14mm
Bone Plug 16mm
Bone Plug 16mm
Bone Plug 18mm
Bone Plug 18mm
Preservation
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Sterilization
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Category
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Base Bone
Anterior Cervical Fusion
Various lengths available
Page 55 of 68
Spine - Neuro
PATELLA WEDGE
Product Code
1606
1607
Product Description
Patella Wedge
Patella Wedge
Preservation
Sterilization
Category
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Base Bone
Base Bone
Spine Surgery
W = 13-15mm, L = 22-30mm
Page 56 of 68
Spine - Neuro
DURA MATER
Product Code
Product Description
Preservation
Sterilization
Category
0001
0002
0003
0004
0655
Dura Mater – Small
Dura Mater – Medium
Dura Mater – Large
Dura Mater – Whole
Dura Mater – Patch
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Ethylene Oxide
Ethylene Oxide
Ethylene Oxide
Ethylene Oxide
Ethylene Oxide
Dura
Dura
Dura
Dura
Dura
Craniotomy/Duraplasty, Dural Replacement, Hernia Repair, Spine
Small: 31 - 50 cm2
Medium: 51 - 99 cm2
Large: ≥100 cm2
Whole: >120 cm2
Patch: 8-30 cm2
Page 57 of 68
OsteoArticular – Oncology Division Total Joints
ELBOW
Product Code
Product Description
Preservation
Sterilization
Category
0280
0080
Whole Elbow – Left
Whole Elbow – Right
Cryopreserved
Cryopreserved
Aseptic
Aseptic
OsteoArticular
OsteoArticular
Joint Replacement
Page 58 of 68
DISTAL FEMUR
Product Code
0082
0081
Product Description
Distal Femur w/ Ligaments –
Left
Distal Femur w/ Ligaments –
Right
Preservation
Sterilization
Category
Cryopreserved
Aseptic
OsteoArticular
Cryopreserved
Aseptic
OsteoArticular
Joint replacements, Joint revision
May be patient matched.
Soft tissue attachments L = min 2cm
Page 59 of 68
HEMIPELVIS
Product Code
Product Description
Preservation
Sterilization
Category
0101
0100
0325
3031r
0324
*Hemi-Pelvis – Left
*Hemi-Pelvis – Right
Hemi-Pelvis – Left
Hemi-Pelvis – Left
Hemi-Pelvis – Right
Cryopreserved
Cryopreserved
Fresh Frozen
Fresh Frozen
Fresh Frozen
Aseptic
Aseptic
Aseptic
Irradiated
Aseptic
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
Tumor resection, Joint replacement
May be patient Matched
*Soft tissue attachments L = min 2cm
Page 60 of 68
SCAPULA
Product Code
0331
0636
0089
0635
1241
1431
1242
1432
1538
1486
Product Description
Scapula – Left
Scapula w/ Humerus – Left
Scapula – Right
Scapula w/ Humerus – Right
Scapula – Right
Scapula – Right
Scapula – Left
Scapula – Left
Scapula w/ Humerus – Left
Scapula w/ Humerus – Right
Preservation
Cryopreserved
Cryopreserved
Cryopreserved
Cryopreserved
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Fresh Frozen
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Irradiated
Aseptic
Irradiated
Irradiated
Irradiated
Category
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoArticular
OsteoAritcular
OsteoArticular
Tumor resection, joint replacement
Features /Benefits:
Page 61 of 68
Oral & Maxillofacial
RIB
Product Code
Product Description
Preservation
Sterilization
Category
0158
1193
0129
Rib
Rib
Rib - Demineralized
Freeze Dried
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Aseptic
Base Bone
Base Bone
Base Bone
Plastic Surgery, Reconstructive Surgery
L > 8cm
W = min 1cm
Page 62 of 68
MANDIBLE
Product Code
Product Description
Preservation
0632
Mandible ETO
Freeze Dried
0630
0631
Hemi-Mandible ETO –
Right
Hemi-mandible ETO –
Left
Freeze Dried
Freeze Dried
Sterilization
Ethylene
Oxide
Ethylene
Oxide
Ethylene
Oxide
Category
Oral-Maxillofacial
Oral-Maxillofacial
Oral-Maxillofacial
Correction of Ridge Defects, Facial Reconstruction, Mandible Replacement
Page 63 of 68
MANDIBULAR & MAXILLA (M&M) BLOCKS
Product Code
Product Description
Preservation
Sterilization
Category
1507
1523
1491
1522
1508
1565
M&M Block – Small
M&M Block – Small
M&M Block – Medium
M&M Block – Medium
M&M Block – Large
M&M Block – Large
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Freeze Dried
Aseptic
Irradiated
Aseptic
Irradiated
Aseptic
Irradiated
Oral-Maxillofacial
Oral-Maxillofacial
Oral-Maxillofacial
Oral-Maxillofacial
Oral-Maxillofacial
Oral-Maxillofacial
Correction of Ridge Defects
Small: W = 10-12mm, L = 15-20mm, H= 8-10mm
Medium: W = 16-18mm, L = 15-20mm, H = 8-10mm
Large: W = 20-22mm, L= 20-25mm, H = 8-10mm
Page 64 of 68
Fresh
FEMUR CONDYLE
Product Code
0776
0772
0760
0771
0774
0815
Product Description
Lateral Femur Condyle – Left
Lateral Femur Condyle – Right
Medial Femur Condyle – Left
Medial Femur Condyle – Right
Whole Femur Condyle – Left
Whole Femur Condyle – Right
Preservation
Fresh
Fresh
Fresh
Fresh
Fresh
Fresh
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Category
Fresh
Fresh
Fresh
Fresh
Fresh
Fresh
Page 65 of 68
Fresh
MENISCUS W/ PLATEAU
Product Code
Product Description
Preservation
Sterilization
Category
0326
Fresh
Aseptic
Fresh
0782
Meniscus w/ Plateau –
Right
Fresh
Aseptic
Fresh
Page 66 of 68
Fresh
ANKLE EN BLOC & TALUS
Product Code
1283
1282
0805
0798
0702
0701
Product Description
Ankle en bloc- Left
Ankle en bloc - Right
Talus – Left
Talus – Right
Talus – Left
Talus – Right
Preservation
Fresh
Fresh
Fresh
Fresh
Cryopreserved
Cryopreserved
Sterilization
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Aseptic
Category
Fresh
Fresh
Fresh
Fresh
OsteoArticular
OsteoArticular
Cartilage Replacement, Articular Resurfacing, Joint Replacement
Total L =12cm including talus, calcaneous, tibia and fibula
Page 67 of 68
UMTB provides the safest and most effective allografts:
The University of Miami Tissue Bank was established in the early 1970’s and has provided safe
and effective musculoskeletal grafts and skin for transplantation without interruption or significant
incident since its inception. The University of Miami Tissue Bank has never felt compelled to treat
tissues with chemicals or irradiation because we make extraordinary efforts to ensure aseptic
procurement and processing to protect the biologic activity of the graft. We always ask the question,
is secondary sterilization of biologic tissue progressive or regressive? Does the margin of “safety” that
it provides make up for the decrement in biologic activity? Does it substitute for poor donor selection
or sloppy procurement? We believe that the American Association of Tissue Banks (AATB) has
adopted appropriate guidelines for Tissue Banking in the United States and the University of Miami is
a proud member of this organization. Does your tissue come from an AATB accredited tissue bank?
We believe that a careful medical and social history is vitally important in identifying suitable
donors and preventing potential disease transmission. University of Miami retrievals are done under
the supervision of a licensed physician who performs a careful examination of the donor and assures
aseptic tissue handling. Bacteriologic surveillance begins with tissue procurement and continues
throughout every component of processing and packaging.
While others may feel compelled to pre treat grafts in detergents and peroxides then terminally
sterilize them for whatever reason, we do not. The use of detergents and peroxides may reduce
bacterial contamination in retrieved tissues however; we have demonstrated diminished biologic
activity in tissues exposed to chemicals such as peroxide. A whiter graft is not a better graft and a
sterile graft may not be biologically active. For this reason, we maintain that appropriate donor
selection, careful medical supervision and aseptic processing are vital to ensure both graft safety and
clinical efficacy.
We fervently believe that the combination of careful donor selection, supervised procurement and
aseptic processing produces ideal safe and effective tissue for transplantation. Our reputation and
record support this.
H. Thomas Temple, M.D.
Director, University of Miami Tissue Bank
Page 68 of 68

UNIVERSITY OF MIAMI TISSUE BANK ALLOGRAFT TISSUE

Transcription

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