for your Pharma-Biotech project

for your
Pharma-Biotech
project
Benefits of the Alsace Region for your project... Come and join us!
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A unique ecosystem for Pharma-Biotech companies
A dynamic and innovative business environment
A world-renowned research and training base
Easy access to the European markets
An international region by its very nature
State-of-the-art infrastructure
Real estate solutions adapted to your needs
An outstanding quality of life
The best of France, in the heart of Europe
and much more...
Access
Business & Tourism
Development Agency
Alsace, a winning location
Alsace
Your gateway to the
European Pharmaceutical
and Biotech market!
for your project
Outstanding skills
in 6 fields:
Welcome to Alsace, in the heart of the wellknown Franco-German-Swiss BioValley!
In this trinational area you will find a
concentration of highly talented Pharma
and Biotech leaders, research and training
centers, all within a radius of 145 km.
 Neurosciences
 Drug Discovery
 Structural biology
 Diagnostics
More than 40% of the global
pharmaceutical leaders are based
 Chemistry
 Oncology
here, benefiting from an outstanding trinational ecosystem open to Europe and
the rest of the world:
 Key players in the Pharma-Biotech
sector, ranging from the Big Pharmas
to state-of-the-art start-ups as well as
renowned CROs and CMOs.
 Numerous foreign companies
established here for their R&D, clinical
trials, manufacturing, their head offices
and/or the marketing of their products or
services.
A tri-national
Pharma-Biotech hub
A closer look at the
Pharma Biotech
industry
International excellence:
 600 Life Sciences companies, including
Europe
 Market: €100 billion
 25,000 companies,
95% of which are SMEs
Lilly’s largest manufacturing site is based in Alsace.
Internationally
scientific experts.

renowned
numerous
top-level technology platforms
 Excellent infrastructure,
and a significant network of teaching hospitals to carry out your clinical trials.
 Alsace is among the larger scientific
hubs in France and it ranks first in
chemistry.
 The presence of the European Pharmacopoeia and the European Science Foundation in Strasbourg.
World
Sources : Eucomed, BPI
France
A culture of excellence
Europe’s third most competitive country for R&D, France is the
As
leading European nation when it comes to
R&D investments in the biotechs and is in
third place for patent registration in this
field.
Some 80% of the workforce in the French
pharmaceutical industry is concentrated
in companies which are members of competitive clusters.
(source LEEM/IMS)
A fast changing market
In 2020, the world market for the pharma
industry should reach $1.3 trillion.
In 2014, Europe accounted for 23%
France : The most attractive R&D Tax Credit in Europe!
of the global market.
France ranks first for corporate taxation relating to R & D activities. The tax credit
(source IMS)
amounts to 30 % of annual R & D expenses. The credit basis considers all R & D expenses
(salaries, payroll taxes, depreciation, patents, etc ...) The cost of subcontracting to
French or European public organizations is accounted for at 200%.
 50, 000 employees in the Life Sciences
 5 out of 10 pharma world leaders
Alsace, in addition to being a business and scientific hub…
is an international and vibrant region
which has always attracted new talent :
 Alsace, the North-Eastern region of France bordering Germany
and Switzerland: a favorite choice for foreign companies and
individuals seeking a dynamic and welcoming
their activities on the European continent.
location for
 With its long standing multi-cultural and multilingual assets,
Alsace is the first international region in France, with the
seat of the European Parliament, Council of Europe and other
international organizations, as well as with a large foreign
community of professionals and students.
 9 Prizes (Nobel, Lasker, Leibnitz…)
 15,000 scientists
 3 universities listed
in the world’s top 100
(Shanghai Ranking – 2014)
Source : Alsace BioValley, Eurométropole
 With two European airports in Alsace, offering more than 100
direct regular flights and three international hubs within 2.5
hours, Alsace offers full access to Europe and the world. It is also
at the crossroads of major European road and rail connections,
including two High Speed TGV lines. Strasbourg : 1h46mn from
Paris (4/16).
An exceptional quality of life with an outstanding
concentration of historic and cultural sites, diversity of lively
cities and quaint villages, beautiful mountains allowing multiple
outdoor activities, the best white wine in the world … and the
highest concentration of Michelin-starred restaurants!
© Istock
France
 The second-largest European market
after Germany
350 Pharma-Biotech companies
Source: Business France
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Highly concentrated R&D
and innovation
Real Estate solutions
adapted to your needs
Scientific
excellence:
 3 Nobel Prizes: Martin Karplus,
chimie (2013) - Jules Hoffmann, physiologie - médecine (2011) - Jean-Marie
Lehn, chimie (1987)
 1 Kavli Prize: Thomas Ebbesen,
nanosciences (2014)
 3 CNRS Gold Medals
 1 Fields Medal
 27 European Research Council (ERC)
With business and innovation parks, business incubators and
more, Alsace has the infrastructure to help you make your
setting up and expansion project a success.
Internationally
Neurex
One of the largest European networks for
research in the neuroscience field.
1,000 Franco-German-Swiss researchers I 100 research laboratories.
www.neurex.org
* Shangaï Ranking 2015
L’ESBS - Ecole Supérieure de
Biotechnologie de Strasbourg :
L’IEEPI
The European Institute for Enterprise
and Intellectual Property
l'IEEPI proposes training in the strategic and offensive aspects of
intellectual property rights, intended for companies in particular.
SATT Conectus Alsace, entry point to
Alsatian research for industrial R&D
The first French tech transfer acceleration
company, Conectus Alsace brings public
lab innovations closer to market through
investing in proof of concept and licensing. SATT Conectus also initiates
and manages public-private research partnerships.
www.conectus.fr/en
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With its comprehensive and high performance training system,
Alsace attracts 67,000 students at the Université de Strasbourg
(listed among world’s top 100 universities*) and the Université de
Haute Alsace/UHA. Alsace also benefits from a dense network of
engineering schools covering many scientific fields : biomedical,
mecatronics, biotechnology, chemistry, physics, polymers and
materials, etc.
www.unistra.fr-www.uha.fr
www.alsacetech.org
One of the seven leading French centres devoted to cancer research.
1,400 researchers and clinicians I 400 research teams
www.canceropole-ge.org
a scientific school with an
international vision
In partnership with the universities of Strasbourg, Basel and
Karlsruhe, the ESBS proposes engineering and biotechnology
training for French, German and Swiss students. The trilingual
teaching focuses on genetic engineering, microbiology, bioinformatics, bio-manufacturing, and modelling, etc.
Numerous Swiss and German R&D centres
complete this impressive list and add
further dynamism to this sector: FMI,
Friederich Miescher Institut for Biomedical
Research (Basel –Switzerland) - BioZentrum,
focused on molecular and biomedical research
and teaching (Basel–Switzerland) - ZBSA, Centre
for the analysis of biological systems/(Freiburg –
Germany) - Max Planck Institute for immunology
and Epigenetics (Freiburg – Germany).
© Istock
L’ISIS
Institute of Supramolecular Engineering and Science
A multidisciplinary research institute in the physics/biology/
chemistry fields .
12 laboratories I 155 employees
www.isis.unistra.fr
Le Cancéropole Grand-Est
EASE - A training centre
unique in its kind in Europe,
devoted to production in
clean room environments
© Vialet Architecture
L’IGBMC
Institute of Genetics and of Molecular and Cellular
Biology
One of Europe’s most prestigious centres for biomedical research.
750 researchers I 47 research teams I 45 nationalities I 45,000 m2
of laboratories
www.igbmc.fr
www.parc-innovation-strasbourg.eu
Outstanding training, suited
to the requirements of health companies
renowned Institutes
Genetics, molecular and cellular biology, chemistry and the neurosciences are all areas of excellence developed by the institutes and laboratories in Alsace belonging to the CNRS (national
centre for scientific research), the Inserm (national institute for
health and medical research) and the universities, including:
Discover for example, the Parc de la Mer Rouge in Mulhouse
which focuses on high technology activities, including life
sciences.
The Strasbourg Innovation Park (170 hectare) is home to
more than 50 key life science players, covering industry,
research and training. It offers numerous services dedicated
to the success of innovative businesses and state of the art
real-estate such as the Bioparc facility.
© Th. Suzan
Located in the «Golden Triangle» for R&D between Baden-Wurtemberg
(Germany) and Northwest Switzerland, Alsace boasts an impressive
concentration of scientific skill. This cross border region has one
of the highest densities of laboratories and researchers in Europe.
Winners of scientific prizes, internationally renowned institutes and
thematic experts apply their highly specialised skills there, enhancing
the area’s reputation far beyond its borders. Alsace has 2 universities,
12 advanced graduate schools, 250 laboratories and more than
4,300 researchers in addition to a University Hospital and numerous
specialised research institutes.
EASE training center
Based near Strasbourg, the EASE production/educational
unit provides students undergoing basic training or interns
with ongoing training in the various aspects of production
in clean room environments, operating under real-life industrial conditions.
www.ease.unistra.fr
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Alsace is home to many talented companies…
Join over 600 Life Science Companies
that have chosen the UpperRhine Valley to set up shop!
Karlsruhe
Catalent France SA
FRANCE
A unique environment to
support our development
High tech production
enabled by research
institutes and talents
At the heart of the
European Pharma
network
Innovating and creating the future
in Alsace! CellProthera develops a
technology to treat patients with
acute myocardial infarct. It is based
on autologous peripheral blood
stem cells which allows the structural and functional regeneration of
myocardial tissue.
Novartis regularly invests in its
Biotechnology Center based in
Huningue, Alsace.
A Contract Research Organization
(CRO) specialized in pharmaceuticals and biotechnologies, Quintiles
is present in Alsace at the Innovation Park in Illkirch.
Deeply rooted in the Alsatian landscape, Cellprothera is nurtured by a
wide regional network of scientific,
financial and industrial partners. Indeed, it was created in 2008 based
on research done in Mulhouse at
the “Institut de Recherche en Hématologie et Transplantation” and
benefits from regional public and
private funding. Local industrial
partners also support the design
and production of CellProthera
equipment.
Professeur Philippe HENON
President & CSO
«These investments enable us to
follow technological innovations
and increase our production capacity. The Biotechnology Centre ensures the production of 5 biopharmaceuticals. A department of thirty
experts supports the development
and technical transfer of new production processes.
Nearly 70 new jobs, mostly highly
technical, have been created since
2010.
Thanks to the dynamism of the region in our domain, we benefit from
a network of experts and research
institutes to assist us in our development.»
Dirk Böhm
Site Head
Alcon S.A.
Capsugel
including :
CellProthera
Nicolas Schaltenbrand
Country Manager France
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An incubator to create your business
more smoothly.
SEMIA , the incubator of innovative
companies in Alsace, helps project
especially in the life science and
health sector by providing human,
financial and technical support.
Mulhouse
Daiichi Sankyo
including :
Novartis Pharma SAS
Weleda SA
Endress & Hauser
Firalis
Konstanz
Basel
SWITZERLAND Zurich
Non-exhaustive map
Alsace BioValley is a world-renowned health cluster enjoying
established connections with American, Canadian, Japanese, German,
Swiss and Belgian clusters. Its Pharma-Biotech experts will identify
new growth, financing and innovation opportunities for your company.
Access unique business solutions (collaborative R&D projects, tailored
introductions to new partners and clients, financial engeneering, etc.)
and take advantage of their established networks in the heart of
Europe!
www.alsace-biovalley.com/en/
www.biovalley.com
Colmar
Freiburg
= Main company locations
A successful health cluster
to help your company grow!
Strasbourg
GERMANY
“Our firm assists laboratories in
the development and registration
of pharmaceutical and biotechnological products (Management of
Clinical Projects, Clinical Operations, Biometry, Medical Affairs
and Quality). At the heart of a
European network for the pharmaceutical industry, the site in Strasbourg benefits from a high-quality
scientific and technological environment, thus contributing to the
development of the bio-pharmaceutical sector in Alsace.”
In Alsace:
everything you need
to innovate !
Stuttgart
including :
Boiron
Lilly
Quintiles Strasbourg
Octapharma
Sanofi R&D
Transgene
11km
Alsace has a world-class
life science environment!
To ensure the successful expansion of
your business, a combination of key
players cover the whole value chain for
Pharma-Biotech.
Discover our Pharma-Biotech companies
online: you may well find your future
clients, partners and suppliers here!
http://www.biovalley.com/industry/excellence-in-companies-2#database
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Access Alsace
your premium partner
The Alsace Business & Tourism Development Agency promotes the
region’s industry, innovation, research & education, arts & culture, and
tourism. It contributes to the region’s growth and global outreach by
attracting companies, entrepreneurs, visitors, scientists, and students.
Our team provides a wide range of free and fully confidential services
to assist and inform interested foreign companies about doing business in
Alsace. Our multilingual experts provide a step by step assistance to companies
setting up and developing operations in Alsace.
5 steps to success
Access Alsace adds value to your project
STEP 1
PLANNING
Optimize a European market
strategy for your operation.
We have been working for
60 years with international
companies on these key
planning elements.
STEP 2
INFORMATION
Finalize your business plan. We
provide accurate information
on costs, support, human
resources, regulations, utilities,
real estate, and suppliers, to
help you build set-up options.
STEP 4
INFRASTRUCTURE
STEP 3
VALUE CHAIN
Access to strategic networks,
partners and providers. FrancoGerman tax adviser?
English-speaking accountant?
Pick’n’pack logistics provider?
We will find them for you!
Get your business up and
running smoothly. We find
land, buildings, offices,
incubators; apply for public
support programs; help
expats find housing, work
permits, education, ...
Fast track your project. Creating
the company; getting power,
telecom, broadband, permits;
hiring local staff; ... and much
more, until your subsidiary is up
and running
Access
Agence d’Attractivité de l’Alsace / Access Alsace • Château Kiener • 24 rue de Verdun F-68000 Colmar
Tel : + 33 (0)3 89 29 81 00 - Fax. +33 (0) 89 29 81 01 • [email protected]
Business & Tourism
Development Agency
Document édité par l’Agence d’Attractivité de l’Alsace
novembre 2015
STEP 5
IMPLEMENTATION