elmex® SENSITIVE PROFESSIONAL™ toothpaste with Pro

elmex® SENSITIVE PROFESSIONAL™ toothpaste
with Pro-Argin™ Technology
For the at-home treatment of dentine hypersensitivity
Active ingredients:
8% arginine and calcium carbonate
Fluoride content:
1450 ppm FFormulation:
Silica-based toothpaste
pH 9.0
Indication:
For daily oral care of patients with pain due to dentine hypersensitivity
Product benefits:
Open dentine tubules caused by exposed dental necks or enamel loss lead to dentine
hypersensitivity. In patients with sensitive teeth cold or sweet food and liquids or
touch can trigger short, sharp pain sensations. The Pro-Argin™ Technology in elmex®
SENSITIVE PROFESSIONAL™ toothpaste deeply occludes the open dentine tubules
and thereby eliminates the cause of pain.
Instant relief with direct application: When applied directly to the sensitive tooth with
a fingertip and gently massaged for 1 minute elmex® SENSITIVE PROFESSIONAL™
toothpaste provides instant pain relief from dentine hypersensitivity.
Lasting relief with regular brushing: Regular use of elmex® SENSITIVE PROFESSIONAL™
toothpaste in daily oral care achieves progressive and lasting sensitivity relief.
Application:
• The product is applied to a gentle toothbrush and teeth are brushed twice daily,
making sure to include all sensitive areas.
• For instant relief the product is applied directly to the sensitive tooth with a fingertip
and gently massaged for 1 minute, once a week or less frequently.
• Children of 6 years and younger: use a pea sized amount for supervised brushing to
minimise swallowing. Consult a dentist or doctor if fluoride is consumed from other
sources.
Package size:
75 ml
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Scientific evidence
Instant dentine hypersensitivity relief with direct application for 1 minute
In a double-blind, parallel group study, 120 subjects applied elmex® SENSITIVE
PROFESSIONAL™ toothpaste, a commercially available desensitising toothpaste
with 2% potassium ion, or a daily use fluoride toothpaste (MFP) directly to sensitive
teeth with a fingertip and gently massaged for 1 minute. Subjects then brushed with
their assigned product and a soft bristled toothbrush twice daily for 3 days. The test
group experienced statistically significant improvements compared to the control
pastes in both air blast and tactile sensitivity score (Fig. 1) immediately and after
3 days of use.
Instant tactile sensitivity relief in vivo with direct application
for 1 minute
Tactile sensitivity
as applied force [g]
Ayad et al. 2009b,
Mississauga, Canada
45
40
*U
Sensitivity relief
*U
35
30
25
20
*
15
*
*
*
10
5
References
Ayad F, Ayad N, Delgado E, Zhang YP,
0
DeVizio W, Cummins D, Mateo LR: ComparBaseline
Immediately
Control 1 with
KNO3 and NaF
Control 2
with MFP
* p < 0.05 compared to baseline
3 days
ing the efficacy in providing instant relief of
®
elmex SENSITIVE PROFESSIONAL™
toothpaste
dentin hypersensitivity of a new toothpaste
containing 8.0% arginine, calcium carbonate,
U p < 0.05 compared to controls
and 1450 ppm fluoride to a benchmark desenFig. 1: Improvement of tactile sensitivity was significantly higher with elmex® SENSITIVE PROFESSIONAL™
toothpaste than with control toothpastes. A higher tactile sensitivity score indicates less hypersensitivity.
sitizing toothpaste containing 2% potassium
ion and 1450 ppm fluoride, and to a control
toothpaste with 1450 ppm fluoride: a threeday clinical study in Mississauga, Canada.
Progressive and lasting dentine hypersensitivity relief with daily oral care
J Clin Dent 20 (2009b), special issue, 115-122
In two double-blind, parallel group studies with similar design, a total of 157 subjects
Ayad F, Ayad N, Zhang YP, DeVizio W, Cum-
with established dentine hypersensitivity were instructed to brush their teeth each
mins D, Mateo LR: Comparing the efficacy
morning and evening for 1 minute with elmex® SENSITIVE PROFESSIONAL™
toothpaste containing 8.0% arginine, calcium
toothpaste or a commercially available desensitising toothpaste with 2% potassium
ion. elmex® SENSITIVE PROFESSIONAL™ toothpaste was significantly (p < 0.05) more
effective in improving hypersensitivity scores (tactile and air blast stimuli) after 2, 4, and
8 weeks (Fig. 2).
in reducing dentin hypersensitivity of a new
carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2%
potassium ion: an eight-week clinical study
on Canadian adults. J Clin Dent 20 (2009a),
special issue, 10-16
Docimo R, Montesani L, Maturo P, Bartolino
M, Zhang YP, DeVizio W, Delgado E, Cummins D, Dibart S, Mateo LR: Comparing the
Progressive and lasting hypersensitivity relief in vivo
Docimo et al. 2009,
Rome, Italy
3.0
3.0
2.5
2.5
Sensitivity relief
*
2.0
*U
1.5
*
*U
1.0
*
*U
0.5
0
Baseline
2
4
weeks
®
8
elmex SENSITIVE PROFESSIONAL™
toothpaste
* p < 0.05 compared to baseline
efficacy in reducing dentin hypersensitivity of
Ayad et al. 2009a,
Mississauga, Canada
Air blast
sensitivity score
a new toothpaste containing 8.0% arginine,
calcium carbonate, and 1450 ppm fluoride
to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical
*
Sensitivity relief
Air blast
sensitivity score
*U
2.0
*
1.5
*U
1.0
*
0.5
study in Rome, Italy. J Clin Dent 20 (2009),
special issue, 17-22
*U
0
Baseline
2
4
weeks
8
Control: Commercially available
desensitising toothpaste
U p < 0.05 compared to control
GABA International AG
Grabetsmattweg
CH-4106 Therwil, Switzerland
www.gaba.com
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Fig. 2: Both studies showed a reduction in air blast sensitivity that was significantly higher with elmex® SENSITIVE
PROFESSIONAL™ toothpaste than with the control toothpaste containing 2% potassium ion.
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