AKR Broch 2006 - National Parkinson Foundation

Transcription

ANNUAL
REPORT | 2007
50 YEARS OF COMMITMENT
TO RESEARCH, CARE, AND HOPE
WORLDWIDE.
NATIONAL PARKINSON FOUNDATION
OUR MISSION:
To find the cause of and the cure for Parkinson disease through research.
To improve the quality of life for persons with
Parkinson disease and their caregivers.
To educate persons with Parkinson disease, their caregivers,
healthcare professionals,
and the general public about Parkinson
disease and its treatment.
“Water Lilies VIII (1963)” – an original painting by Jose Bernal,
whose PD has never limited his artistry. Or his generosity to NPF.
| ANNUAL REPORT 2007
Table of Contents
3
Joint Message
4
NPF History
6
Honorary Board of Governors
7
Officers and Directors
8
Research & Grants
14
Scientific Advisory Board
15
Centers Review Board
16
Editorial Committee
18
NPF Centers of Excellence
19
NPF Care Centers
19
NPF Outreach Centers
20
NPF Chapters
23
Programs and Services
26
Events and Activities
28
NPF Donor Honor Roll
35
NPF Financial Report
Annual Report
2006-07
1
Are
you with
us?
his year of 2007, we observe the 50th anniversary
of the founding of the National Parkinson
Foundation. In 1957, little was known about
Parkinson disease. In those days there was no levodopa, no
specific medications, no deep-brain stimulation, no
professional referrals, and very little knowledge about the
disease itself. The basic care consisted of not much more
than physical therapy – mostly massages – and loving
care. That, therefore, was the original function of the
Foundation that Mrs. Levey created for the benefit of her
husband, who had Parkinson disease, and for all others
similarly situated in and around Miami, Florida.
T
For the next 22 years, until her death at age 92, Jeanne
Levey nurtured NPF and watched it grow, as more and
more people became involved with and benefited from
the work of the Foundation. In just a few years the
annual budget grew to a whopping $50,000.
Today NPF is the largest and
oldest national Parkinson
foundation in the United
States. NPF supports
Parkinson-related research,
patient care, education,
training, and outreach. Our
Educational pamphlets, listed
elsewhere in this Annual
Report, cover a variety of
t o p i c s o f i n t e re s t t o t h e
Parkinson community, are
unique in their genre, and are
distributed free of charge to
anyone that requests them.
persons with Parkinson disease, and our Community
Partners Program (CPP) seeks to identify underserved
communities, forge alliances with health-care providers,
and make available resources not otherwise known or
accessible to thousands of persons needing help.
NPF sponsors a biennial International Symposium on
Parkinson Research, assembling pre-eminent researchers
worldwide to present and discuss the latest investigative
developments in the field of Parkinson disease. Our
website, www.parkinson.org, is the most visited website
of its kind and includes such interactive features as Ask
the Doctor, Ask the Surgeon, and Ask the Parkinson
Dietician. This is, in short, a holistic, worldwide
organization that Mrs. Levey probably never dared to
dream of when, half a century ago, she took the first steps
to create the National Parkinson Foundation.
Yet the observance of our
50th anniversary brings
mixed feelings, as our pride
in the work that has
been done is tempered by
t h e re a l i z a t i o n t h a t –
notwithstanding the huge
strides made in understanding the disease –
the cause of and cure for
Parkinson disease has not
yet been found. We remain
committed to finding the
cure and to continuing to
help those who must deal
with the disease every day
of their lives: people with Parkinson disease, their families,
and their caregivers. As we enter a new year, our most
fervent hope is that one day soon, we will literally have put
ourselves out of business, because our work will have been
done. That, of course, could never be possible without the
continued support of our donors, for which we will always
be grateful. But for the generosity of our donors, the
National Parkinson Foundation could not maintain its
tradition of service to the Parkinson community. On this
occasion we would therefore like to acknowledge our
donors and thank them for their loyalty and support.
Joint Message
There are now 46 affiliated Chapters of NPF throughout
the United States, Puerto Rico, and the Bahamas. We
have 38 NPF Centers of Excellence in the United States,
including 11 in four continents around the world;
11 NPF Care Centers; and 9 NPF Outreach Centers.
Our Chapters and Centers work with hundreds of
persons in Support Groups throughout the United States,
which Support Groups are listed on our website. Our
Allied Team Training for Parkinson (ATTP) Program
has trained over 300 professionals in more than one
dozen venues around the country in the proper care of
Paul F. Oreffice, Chairman
Nathan Slewett, Chairman Emeritus
3
50 Years of
Research, Care, and
Hope Worldwide
A BRIEF HISTORY OF THE NATIONAL PARKINSON FOUNDATION
In 1817 London physician James
Parkinson first described Parkinson
disease when he published "An Essay
on the Shaking Palsy." Since that time,
scientists the world over have struggled
to unravel the many mysteries of this
condition. Although a cure has not been
found, it is important to note the many
significant advances in treatment and
care for persons with Parkinson disease.
When Mrs. Jeanne C. Levey founded
the National Parkinson Foundation in
1957, very little was known about the
disease itself. Basic care and treatment
options were limited. Even levodopa,
the first Parkinson medication, would
not be available for another ten years.
In the course of the past 50 years, NPF has invested
more than $150 million dollars in research and care
initiatives.
The Foundation is equally committed to basic
research for the cure and clinical research, designed
to develop the most effective strategies for bringing
the accumulating knowledge from the laboratory
and clinical studies to the hands of care providers
and people living with Parkinson disease.
NPF’s Scientific Advisory and Centers Review
Boards are made up of leading researchers,
prominent physicians and experts in healthcare
delivery, who oversee a rigorous
process by which every funded
project is reviewed. The result has
been the funding of innovative
research and the development
of a worldwide network of 58
Designated NPF Centers, setting
new standards of excellence in:
research, comprehensive care,
and outreach.
Together with ongoing funding for and support of
leading-edge research efforts, NPF’s many programs &
services are at the forefront of fighting back and moving
forward. From training healthcare providers and allied
health professionals to better initiate and integrate care,
to providing an exceptional range of public information, to fostering innovative outreach efforts in the
community, NPF brings tools, talent & inspiration to
all those living with and striving against Parkinson:
• Chapter & Support Group Network a grassroots coalition of 45 affiliated Chapters
and over 900 support groups listed on the NPF
website.
• Allied Team Training for Parkinson (ATTP) a team-based national training initiative for
health professionals designed to improve
interdisciplinary care in Parkinson disease.
• Community Partners for Parkinson Care (CPP) a national outreach initiative, focused on the
development of partnerships to create innovative
strategies for overcoming the cultural, language,
geographic and health barriers that limit access
to education, support and comprehensive care
in Parkinson disease.
• Young-Onset Parkinson Network Conference an annual event coordinated by and for people
living with young-onset Parkinson disease. The
2007 conference was held in Chicago on July
5th -7th, visit www.parkinson.org/yopn for details.
Information and Education for
the Parkinson Community
NPF is committed to providing the most current
and accurate information about Parkinson disease
and its treatment and expends over $1,000,000
annually on its information and education services,
all of which information is provided free of charge
to the public. Services include:
• The NPF Website: www.parkinson.org is the
centerpiece of NPF information services, receiving
as many as 100,000 visitors each month. Online
forums including the very popular Ask the Doctor
enable users to have questions answered by leading
professionals in each specialty area.
• The Parkinson Report is an informative and
inspirational quarterly magazine featuring articles
written by Parkinson researchers, medical practitioners and caregivers. The Foundation distributes
over 100,000 copies of each issue, with a readership of some 400,000 individuals. Current and
prior issues dating back to the fourth quarter of
2001 are available on the website.
• The Parkinson Education Series encompasses
the most complete body of literature on all
aspects of the disease written by noted clinical
experts, specifically for people with Parkinson
disease and their families. The 12-volume series
is available in both English and Spanish.
200,000 copies are distributed annually.
• International Symposium on Parkinson Research a biennial conference devoted to the latest
scientific and clinical advances.
• Collaboration for Care an annual meeting of the medical directors and
coordinators of NPF’s network of Centers
• Patient Symposia live and/or webcast educational events designed
for persons with Parkinson and their carepartners
and presented by leading experts in the field
NPF is proud of its history and its
contributions to improving the lives
of those affected by Parkinson disease.
While much has been accomplished
during the past 50 years, it is clear
that much more remains to be done.
NPF is poised to lead the effort.
5
Honorary Board of Governors
NPF has been fortunate to benefit from the longtime service and dedication of the members of its
Honorary Board of Governors and its late Chairman, Bob Hope. Upon Bob Hope’s passing,
his daughter, Linda Hope, graciously agreed to serve as Vice Chair of the Honorary Board of Governors,
and Mr. Dick Clark, a longtime friend and generous supporter of NPF, agreed to become chair.
The NPF Honorary Board of Governors is composed of the following outstanding individuals,
to each of whom the Foundation owes a debt of gratitude:
Dick Clark, Chair
Edwin A. Levy
Wall Street Financier
Linda Hope, Vice Chair
Dr. Sidney L. Olson*
Henry Backus*
Robert A. M. Coppenrath
former Vice-Chairman of AGFA Corporation
Paul F. Oreffice former Chairman
of the Dow Chemical Company
U.S. Senator Claiborne Pell
Phyllis Diller
Eric Emanuel*
Betty Ford
President Gerald Ford*
Kenneth O. Gilmore
former Editor-in-Chief, Readers’ Digest, Inc.
David B. Golub
Managing Director of Centre Partners
Management LLC
Bob Hope*
David Laventhol
Editor-At-Large, Times Mirror
Sylvia Sack
Publisher
Professor Erich Segal
Author
Richard B. Stolley
Senior Editorial Adviser, Time, Inc.
Nicholas L. Teti
President and CEO, INAMED Corporation
Martin Tuchman
Chairman and CEO of Interpool, Inc.
Norma G. Udall
U.S. Congressman Henry Waxman
U.S. Senator Paul D. Wellstone*
*Deceased
Officers and Directors
The National Parkinson Foundation is privileged to have an outstanding and dedicated group
of volunteers who donate their time and talents by serving as Officers and Directors of the Foundation.
Without their selfless efforts, the work of the Foundation would not be possible.
CHAIRMAN
Paul F. Oreffice*
ASSISTANT SECRETARY
W. James Orovitz*
CHAIRMAN EMERITUS
Nathan Slewett, Esq.*
HONORARY DIRECTOR
Mr. Carol Greenberg
VICE CHAIRMAN
Daniel Arty, CPA*
MEMBERS AT LARGE
A. Jeffrey Barash, Esq.
Marshall R. Burack, Esq.*
Carmen Cartaya, Esq.
Bernard Fogel, MD
Honorable Shelley Kravitz
Edward Pazicky*
Clarence Pittman
Enrique Sosa
Javier Talamo, Esq.
Robert H. Traurig, Esq.
Bruce Wisnicki
PRESIDENT & CEO
Jose Garcia-Pedrosa, Esq.
PRESIDENT EMERITUS
Harold P. Kravitz, Esq.*
EXECUTIVE VICE-PRESIDENTS
E. Richard Alhadeff, Esq.*
Edythe Kay-Marsa*
VICE-PRESIDENTS
JoAnn Pepper Oreffice
Martin Gelb*
TREASURER
Senator Paul B. Steinberg*
SECRETARY
Alan M. Slewett*
HONORARY MEMBERS
Harold Beck
James T. Cordy
Michael Landa
Ira Levenshon
Harriet Rubens
Dennis C. Wallach
*Member of the Executive Committee
NPF Senior Professionals
Jose Garcia-Pedrosa, Esq.
President and CEO
Pamela Olmo
Director of Finance & Administration
Michael S. Okun, MD
National Medical Director
Rhonda Roseman-Seriani
Director of Development
Ruth Hagestuen, RN MA
Director of Field Services
7
$
4,641,388
NPF Grants Approved in 2007
NPF Center Grants . . . . . . . . . . .$ 3,641,596
- Research (18) . . . . . . . . . . . . . 1,027,855
- Care (22) . . . . . . . . . . . . . . . . . . 962,139
- Outreach (39) . . . . . . . . . . . . . . 1,651,602
Individual Research
Grants (8) . . . . . . . . . . . . . . . . . . .
320,000
University of Miami Parkinson
Project and Brain Bank . . . . . . . .
450,000
NPF Chapter Grants (4) . . . . . . . .
29,792
Parkinson Action Network
(PAN) – Advocacy . . . . . . . . . . . .
200,000
GRAND TOTAL . . . . . . . . . . . . . . .$ 4,641,388
NPF 2007 Grants by Type:
Research
& Grants
The National Parkinson
Foundation supports laboratory and clinical research
throughout the world through
designated NPF Centers of
Excellence – as well as by
providing grants to individual
investigators to develop new
and promising ideas that
may help find the cure for
Parkinson disease.
NPF is equally committed
to laboratory and clinical
research, which together
deliver accumulating knowledge from the laboratory
and clinical studies into
the hands of care providers
and people living with
Parkinson disease.
Outreach
Advocacy
12%
5%
36%
26%
39%
4%
30%
34%
14%
Comprehensive
Care
Research
NPF also collaborated with
the University of Miami Miller
School of Medicine in creating
one of the world’s first brain
banks and continues to
support the NPF/UM Brain
Endowment Bank. Tissue
collected from both healthy
and diseased brains is
available to researchers
anywhere in the world.
CENTER GRANT RECIPIENTS 2007-2008
NPF DOLLARS AT WORK
Research:
The National Parkinson Foundation values
its partnership with Centers and works in
close collaboration with them to improve
the quality and accessibility of care, provide
professional and community education
about Parkinson disease.
• Toronto Western Hospital established a
multicentre, international collaboration examining
the role of environmental/dietary exposures in
modifying the age of onset of Parkinson's disease
associated with LRRK2 mutations. Fourteen centers
from 10 countries are participating, collectively
having identified over 240 subjects with Parkinson's
disease due to LRRK2 mutations.
In 2007, the National Parkinson Foundation
received more applications for designation as
an NPF Center than ever before, from both
University-based and community Parkinson
Centers. With well-defined designation criteria established in the Charter for Centers,
NPF was pleased to grant designation to a
total of 58 Centers: 38 Centers of Excellence,
11 Care Centers and 9 Outreach Centers.
Nine of the 58 designations were new partnerships which expand our network in the
U.S. and around the world.
• At the University of North Carolina, a study is
ongoing to evaluate cognitive changes and wordfinding problems associated with deep brain
stimulation.
A major goal of the NPF Center grant process
is to develop hypothesis-driven models of best
practice in research, care and outreach. NPF
Centers demonstrate consistent productivity,
creativity and innovation, whether in the
research laboratory, enhancing comprehensive
clinical care and/or partnering with community agencies to extend outreach services to
diverse communities. A sample of Center
grants is listed below in the three areas of
research, care and outreach:
• At Northwestern University: A study to increase
understanding of behavioral and neural deficits in
impulse control disorders in persons with Parkinson
disease. Findings will have important implications
for guiding patient management and therapeutic
interventions.
• At Pacific Parkinson’s Research Centre, the
Falls Prevention study helps identify new variables
for screening persons with Parkinson disease at risk
for falling, and help to focus rehabilitation efforts to
reduce the current risk of falls.
• At Tel Aviv Sourasky Medical Center, an ongoing
study looking at the “Nicotine protection effect in
Parkinson disease: Do genetic alterations in nicotinic
acetylcholine receptor subunit genes confer risk or
prevent the disease?”
• A Baylor College of Medicine pilot study to
determine if the medication, acamprosate, can
alleviate compulsive behaviors in persons with
Parkinson disease without the need for adjusting
current PD therapy.
9
CENTER GRANT RECIPIENTS 2007-2008
Comprehensive,
Interdisciplinary Care:
• The ParkNet trial demonstrated the effectiveness
and feasibility of training allied health professionals
in community settings with specialized skills to
benefit people with Parkinson disease. ParkNet has
been awarded with the “Zorgen voor Morgen”
award for the best and most innovative health care
project in the Netherlands in 2006. Nijmegen
Parkinson Center, the Netherlands
• The TULIPS program was designed to describe the
special needs of people with Parkinson's disease, for
staff training in assisted living and long term care
facilities. The TULIPS core training video won a
Silver Telly Award, the top honor for outstanding
local, regional and cable TV commercials and
programs, plus video and film productions.
Struthers Parkinson’s Center, Minnesota
• Two NPF Centers in Oregon collaborated
to develop a critical information form,“Caring
for the Hospitalized Parkinson's Patient.”
This form acknowledges individual
differences and fosters personalized
care planning for the person with
Parkinson disease. The Oregon
Centers have received calls of
interest from other PD
Centers throughout the U.S.
Parkinson's Resources of
Oregon and Oregon
Health & Science
University
(continued)
• At the Tel Aviv Sourasky Medical Center in Israel,
interdisciplinary care has been expanded to address
caregivers’ needs. Also, to support the genetic
research in the laboratory, the Center has developed
a genetic program and counseling in regards to
LRRK2 G20195 mutation.
• PD Pilates program was piloted and launched,
receiving press coverage in 27 articles nationwide.
Program inquiries prompted website information on
program for others wishing to develop in their own
area. Oregon Health & Science University
• FOCUS - Finding Opportunities for Care and
Support – is a year-long program for recently
diagnosed patients with emphasis on individual
choice, patient empowerment, and education on use
of an interdisciplinary team. Variety of information
sheets created on topics relevant to living well with
Parkinson disease. Struthers Parkinson’s Center, MN
Outreach:
• The creativity and commitment displayed in
developing outreach services for the underserved
contributes to our ever-expanding goals of
improving access to well-informed care for
everyone with Parkinson disease.
• Beth Israel Deaconess Medical Center
established videoconferencing capability with
rural Outer Cape Health Services community
health center to facilitate participation in team
meetings; to offer provider education for primary
care physicians and to offer educational programs
for geographically isolated patients and care
partners. The University of Kansas and
Markham Stouffville Hospital in Ontario
also have well-developed telemedicine
programs for their rural communities.
• Bellevue Hospital provides comprehensive
healthcare and social services to people with
Parkinson's and their caregivers in Spanish and
English, with interpreters available for all other
major languages. The Muhammad Ali Center
Parkinson has a dedicated Hispanic outreach
coordinator.
• Harvard Medical School/ Massachusetts General
Hospital is developing outreach services in the
Boston Chinatown community.
• The "Falls Prevention Workbook" was developed
at the Lee Parkinson’s Outreach Center in Fort
Myers, Florida and distributed to older adult
communities and families with Parkinson's disease.
The Fort Myers group also co-produced four video
segments that supplement the "Falls Prevention
Book.”
• At Johns Hopkins University, “A Parkinson
Disease Depression Detection Study in Community
Based Neurology Practices” is increasing knowledge
of optimal methods of screening for depression
within this population.
GRANTS
• University of California, San Francisco
neurologists provide on-site consultation to
community agencies as a strategy for working with
minority communities. UCSF has also developed
web site modules for patients/caregivers and
professionals in various aspects of treatment and
management of PD. Several modules have been
translated into Spanish, Chinese and Japanese.
• In some cases, NPF designation has contributed to
Centers’ abilities to attract additional grant awards
from outside funding sources. Two examples are:
• Kings County Hospital,
Brooklyn Outreach program
has received widespread
recognition from other PD
groups, researchers and
movement disorders
specialists for the
Brooklyn Parkinson
Group Dance for PD
program, developed in
collaboration with Mark
Morris Dance Group.
11
Individual Research Grant
Recipients 2007-08
Melissa Geddie, Ph.D.
Whitehead Institute for Biomedical Research
“Metal Ion Transport in Parkinson's Disease”
Parkinson's Disease (PD) is the second most common
neurodegenerative disease, affecting approximately 1%
of the population older than 65. Although the majority
of PD cases have unexplained causes, mutations (changes
in the DNA) in several genes have been linked to familial
PD. Recently, a genetic procedure to discover new genes
called linkage analysis identified ATP13A2 (Park9), a metal
ion transporter as being important to PD. This new gene,
when mutated (undergoes a change in its DNA or genetic
information), seems to be responsible for an early-onset
PD. Investigators at the Whitehead Institute have found
that the yeast version of this protein, YOR291wp,
suppresses the toxicity of another important PD protein,
alpha-synuclein. YOR291wp (the yeast protein) is one of
three metal ion transporters (transporters that carry metals
such as iron that may be important to the development
of neurodegenerative diseases) that affects alpha-synuclein
toxicity, which is a toxicity that seems to be important to
the development of PD. The goal of this project is to
understand the biological function of Park9/YOR291w
and the role that metal ion transport plays in alphasynuclein toxicity. Ultimately, it is hoped that from this
research that novel brain targets will emerge that can
be used for PD therapy.
Kangning Liu, Ph.D.
University of Pennsylvania
“Understanding the Role of LRRK2
Protein in Parkinson’s Disease”
The Leucine Rich Repeat Kinase 2 (LRRK2) gene contains
the most frequent PD-causing mutations (changes in DNA
that may lead to the development of PD) identified to
date. How these LRRK2 mutations induce PD remains
unknown. Researchers at the University of Pennsylvania
are generating transgenic flies that will express wild type
(normal) human LRRK2 and mutant forms (forms with
abnormal DNA that may impact the cause of PD). These
researchers will test the hypothesis that the mutant forms
with disrupted DNA sequences in their genome will
selectively affect the dopamine cell integrity and ultimately
brain dopamine levels. The investigators will further examine the interaction between LRRK2 and environmental
toxins that may be at least partially responsible for PD.
The UPENN investigators hope that the flies from their
experiments will provide clues to help discover genetic
modifiers of LRRK2, which in turn may shed light on
the causes of PD.
Roy M. Smeal, Ph.D.
University of Utah
“Characterization of NMDA receptor subtypes in
the cortical and thalamic afferents to the striatum”
The motor symptoms of PD are primarily the result of the
death of dopamine-producing cells in the midbrain. In the
striatum, the main input nucleus of the basal ganglia (the
group of structures that seem to be abnormal in PD),
dopamine interacts with another major brain chemical,
glutamate which is used by the the brain regions referred to
as the cerebral cortex and the thalamus. Abnormal brain
firing by cells in the basal ganglia referred to as neuronal
oscillations and synchrony are observed in both PD patients
and in animal models of PD. This abnormal firing seems to
be correlated with changes in the distribution of subtypes of
the brain chemical glutamate’s NMDA receptors. These
changes in the subunit composition of NMDA receptors
for glutamate may contribute to the pathological electrical
behavior of brain cells, and contribute to the symptoms
observed in PD. Molecules interacting with the brain
chemical glutamate’s NMDA receptor have shown promise
as potential drug therapies for animal models of PD, but the
reasons for this important function remain unknown. There
seems to be a dominant role for the brain structures called
the thalamus and the cerebral cortex in orchestrating brain
firing patterns. This team at the University of Utah will try
to better understand NMDA receptor subunit composition
between the striatum (an important basal ganglia brain
region) and the thalamus/cerebral cortex. These investigators
have developed a novel rat brain slice preparation to examine
glutamate receptor subtypes in these regions in both the
normal and the PD brain. Understanding these receptors,
their location, and their function may help to develop
focused therapies for PD symptoms.
Nutan Sharma, M.D., Ph.D.
Massachusetts General Hospital
Carla Verstappen, Ph.D.
Parkinson Center Nijmegen
“Mitochondrial dysfunction in genetic parkinsonism:
what muscles can tell us about the brain”
Optimized treatment strategies for PD are urgently
needed, in particular approaches that delay or perhaps
even prevent the disease altogether. Recent evidence
suggests a relationship between dysfunction of mitochondrial pathways (dysfunction in the energy supply
part of the cells) and PD. In particular, animal models of
genetic forms of PD display these mitochondrial defects.
These investigators from the Netherlands speculate that
the mitochondrial dysfunction will be observed in muscle
biopsies of patients with genetic forms of PD. This
investigative team will be taking small biopsies from
muscles in one leg of patients with a genetic form of PD
Edward A. Fon, M.D.
McGill University
“Analysis of parkin-mediated ubiquitination
by quantitative mass spectrometry”
Important advances have been made using molecular
and genetic approaches to studying PD, and in recent
years, several genes have been identified which may cause
familial forms of PD. Of these genes, "parkin" accounts
for a large proportion of cases. These investigators from
McGill University are interested in understanding the
normal function of parkin and how defects may lead to
PD. Parkin is a key enzyme in the “ubiquitin” system.
It functions by attaching a small protein called ubiquitin
onto other proteins, thereby changing their makeup and
ultimately promoting their destruction. Ubiquitination
can be thought of as tagging proteins for disposal by
brain cells. Loss of parkin activity is believed to result
in the death of susceptible brain cells. Remarkably, the
majority of parkin mutations (changes in the DNA
genetic material) do not abolish parkin activity. How
then do they lead to disease? These investigators believe
that many of the parkin mutations modify the types of
linkages that attach ubiquitin (the tagging protein) to
other proteins. As the type of ubiquitin attachments may
alter the fate and function of the tagged protein, they
propose that these changes may explain how most parkin
mutations lead to PD. Until recently, it has not been
possible to accurately assess the types of ubiquitin attachments to proteins. This group from McGill University
will use Absolute Quantification of Ub (AQUA), a novel
mass spectrometry technique, to characterize how parkin
attaches ubiquitin onto target proteins. It is hoped that
by characterizing such a fundamental aspect of parkin
function it will point researchers towards better
treatments for PD.
13
GRANTS
“TorsinA: Critical for Dopamine Neuron Survival”
Apoptosis, a potentially normal process of programmed
cell death in the brain, is thought to play a role in the
pathogenesis of PD. Thus, in order to slow or halt the
progression of PD, it is essential to understand the factors
that affect apoptosis. Investigators at the Massachusetts
General Hospital have identified the protein, torsinA,
as essential to the survival of dopamine brain cells in a
transgenic mouse model (a genetic model of a mouse
with PD). TorsinA was first identified because of research
into a similar disease known as early-onset generalized
dystonia or DYT-1 dystonia. The function of torsinA is
unknown. These investigators have found, in a genetically
engineered mouse model, that expression of mutant
torsinA results in a 60% reduction in dopamine cells in
the substantia nigra, which is the brain region that shows
the most loss of cells in PD. These investigators found
that in a transgenic mouse model expressing normal
torsinA there was a 90% increase in dopamine cell
survival in the substantia nigra. These data indicated that
torsinA is crucial for dopamine cell survival. This
investigative team will determine the intracellular role of
torsinA in promoting the survival of dopamine neurons.
Results may help us to develop techniques to improve
survival of these cells in PD.
and they will be comparing them to biopsies of patients
with a sporadic (unknown cause) form of PD. Results
will also be compared to muscle samples from a large
group of healthy persons. This project may clarify the
possible role of mitochondrial dysfunction in genetic
versus sporadic forms of PD, and define the molecular
mechanisms underlying mitochondrial dysfunction in
PD. The results may aid the future development of
disease modifying agents for PD.
Scientific Advisory Board
The NPF Scientific Advisory Board (SAB) is comprised of leading researchers and prominent physicians
who specialize in movement disorders. This group, which is independent of the Foundation, serves in an advisory capacity
by reviewing the scientific and medical grant applications submitted annually to NPF for consideration
by the NPF Board of Directors. Following established procedures, the SAB evaluates all applications and recommends
to the NPF Board of Directors those grants that the SAB believes should be funded.
The current SAB members, all of whom donate their time and talents without charge, are the following:
Ariel Y. Deutch, Ph.D. (Chair)
Franz F. Hefti, Ph.D.
Vanderbilt University School of Medicine
Nashville, Tennessee
Avid Radiopharmaceuticals, Inc.
Philadelphia, Pennsylvania
Pradeep Bhide, Ph.D.
Irwin J. Kopin, M.D.
Harvard Medical School
Cambridge, Massachusetts
National Institute of Neurological Disorders
and Stroke, National Institutes of Health
Bethesda, Maryland
Donald Calne, D.M., F.R.C.P. (Emeritus)
George Paulson, M.D., F.A.A.N.(Emeritus)
University of British Columbia
Health Sciences Centre Hospital
Vancouver, Canada
The Ohio State University Hospital
Columbus, Ohio
Ian J. Reynolds, Ph.D.
David F. Clayton, Ph.D.
University of Illinois
Urbana, Illinois
University of Pittsburgh
Pittsburgh, Pennsylvania
David Robert Sibley, Ph.D.
Robert H. Edwards, M.D.
University of California, San Francisco
San Francisco, California
Bethesda, Maryland
Julia George, Ph.D.
A. Jon Stoessl, M.D., F.R.C.P.C.
University of Illinois
Urbana, Illinois
Health Sciences Centre Hospital
Vancouver, Canada
Ann M. Graybiel, Ph.D.
Massachusetts Institute of Technology
Stella E. Tsirka, Ph.D.
University Medical Center at Stony Brook
Stony Brook, NY
Mark Guttman, M.D., F.R.C.P.C.
Markham-Stouffville Health Centre
Toronto, Canada
Mark Hallett, M.D.
Anne B. Young, M.D., Ph.D.
Bethesda, Maryland
NPF Centers Review Board
The Board of Directors of the National Parkinson Foundation has approved a Charter for Centers of Excellence (COEs),
NPF Care Centers, and NPF Outreach Centers. The Charter outlines the standards required of Centers,
describes the relationship between the Centers and the Foundation, and sets forth the procedures applicable to
applying for and obtaining both designation as a Center and grants to designated Centers.
Appointments are made by the NPF Board of Directors for three-year periods, renewable as may be warranted.
The following persons have been appointed to serve on the NPF Centers Review Board:
Ruth Hagestuen, R.N., M.A., (Chair)
Jean Hubble, M.D.
National Parkinson Foundation
Miami, Florida
Executive Director, Global Medical
Strategy Leader – Neurology
Johnson & Johnson Pharmaceutical Services, LLC
Raritan, New Jersey
Lisette K. Bunting-Perry, M.Sc.N., R.N.
Assistant Clinical Director, Parkinson’s Disease
Research, Education and Clinical Center
Philadelphia VA Medical Center
Ricky Joseph, Ph.D. OTR/L
Assistant Professor, Department of Occupational
Therapy, School of Allied Health Sciences,
Medical College of Georgia
Augusta, Georgia
Eugene Chi-ho Lai, M.D., Ph.D.
Professor, Department of Neurology
Baylor College of Medicine
Houston, Texas
Ron Pfeiffer, M.D.
Professor and Vice-Chair of Neurology
University of Tennessee Health Science Center
Memphis, Tennessee
Elaine Cohen, Ph.D.
Consultant in Research/Evaluation and
Program Development, Field Services
New York, New York
Robert L. Rodnitzky, M.D.
Marge F. Gibbons, Ph.D.
Roger P. Rossi, D.O.
Consultant / Clinician
American Retirement Community, Inc.
Holiday, Florida
Assistant Professor
Physical Medicine and Rehabilitation
JFK Johnson Rehabilitation Institute
Edison, New Jersey
Chairman, Department of Neurology
University of Iowa
Iowa City, Iowa
Gladys González-Ramos, Ph.D.
Associate Professor of Social Work
New York University
Consultant to Field Services
New York, New York
Barbara G. Vickrey, M.D., M.P.H.
Professor and Vice Chair
Department of Neurology
University of California, Los Angeles
Mark Hallett, M.D.
Clinical Director, Section of Neurology
and Stroke (NINDS)
Bethesda, Maryland
15
Editorial Committee
The NPF Editorial Committee is responsible for the Parkinson Report, in both electronic and print formats.
Committee members oversee the form and quality of the materials published, set standards to be observed,
and see to it that the information provided in the Report is presented fairly and accurately.
The members of the Editorial Committee are the following:
Adolfo Diaz
Michael S. Okun, MD
Field Services Manager
National Medical Director
Ruth Hagesteun, R.N., M.A.
Rhonda Roseman-Seriani
Director of Development
Sharon Metz, R.N., M.P.H.
Centers Manager
50 Years On:
NPF’s Network of Centers
Spans the Globe
Based at leading medical and research institutions,
CENTERS
NPF’s international network of 58 designated
Centers serves people with Parkinson disease, their
families and communities, and healthcare professionals
worldwide. The Centers continually set new
standards of excellence and innovation in NPF’s
core interests: research, comprehensive care and outreach.
The designation of NPF Center of Excellence
requires the highest quality comprehensive care and
most advanced research in Parkinson disease.
Its hallmarks are the inspiration, motivation and commitment
that lead to the best practices, the most
appropriate outreach to all families affected by
Parkinson disease, and the latest groundbreaking
research that will ultimately lead to a cure for
this challenging disease.
17
NPF CENTERS OF EXCELLENCE
Muhammad Ali Parkinson Center
Barrow Neurological Institute
Phoenix, Arizona
Victorian Comprehensive Parkinson's Program
Cheltenham, Victoria, Australia
University of Southern California, Parkinson's
Disease and Other Movement Disorders Center
Los Angeles, California
University of California, San Francisco
Parkinson's Disease Clinic and Research Center
San Francisco, California
The Parkinson's Institute and Clinical Center
Sunnyvale, California
University of Calgary/Calgary Health Region
Calgary, Alberta, Canada
Georgetown University Hospital
Washington, DC
King's College London
London, England
University of Florida Parkinson's Disease
& Movement Disorders Center
Gainesville, Florida
Miller School of Medicine
University of Miami, Parkinson's Disease
and Movement Disorders Center
Miami, Florida
University of South Florida Parkinson's Disease
Tampa, Florida
University of Alberta
Edmonton, Alberta, Canada
Medical College of Georgia
Movement Disorders Program
Augusta, Georgia
Markham Stouffville Hospital
Centre for Movement Disorders
Markham, Ontario, Canada
Phillipps University
Dept. of Neurology, Faculty of Medicine
Marburg, Hessen, Germany
Toronto Western Hospital Movement
Disorders Center
Toronto, Ontario, Canada
Hawaii Parkinson Disease Center of Excellence
University of Hawaii
Honolulu, Hawaii
Pacific Parkinson's Research Centre
Vancouver, BC, Canada
Northwestern University Parkinson's Disease
Chicago, Illinois
Indiana University/Clarion
Indianapolis, Indiana
Mount Sinai School of Medicine
New York, New York
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
The Movement Disorders Center
at Beth Israel Medical Center
New York, New York
University of Kansas Medical Center Parkinson's
Disease and Movement Disorder Center
Kansas City, Kansas
University of Louisville
Division of Movement Disorders
Frazier Rehab Neuroscience Institute
Louisville, Kentucky
Johns Hopkins Parkinson's Disease
Baltimore, Maryland
Beth Israel Deaconess Medical Center, Parkinson's
Disease & Movement Disorders Center
Boston, Massachusetts
Boston, Massachusetts
Struthers Parkinson's Center
Golden Valley, Minnesota
Nijmegen Parkinson Center
Nijmegen, Netherlands
University of Rochester Medical Center
Rochester, New York
University of North Carolina at Chapel Hill
School of Medicine
Chapel Hill, North Carolina
Oregon Health & Science University
Parkinson Center of Oregon
Portland, Oregon
University of Pennsylvania, Parkinson’s Disease
Parkinson's Disease and Movement Disorders
Centre, National Neuroscience Institute
Singapore, Singapore
Vanderbilt University Medical Center
Nashville, Tennessee
Baylor College of Medicine, Parkinson's Disease
Center & Movement Disorders Clinic
Houston, Texas
Kings County Hospital /
SUNY Downstate Medical Center
Brooklyn, New York
19
NPF CARE CENTERS
The Parkinson Center at Hoag
Hospital Presbyterian
Newport Beach, California
Health South Rehabilitation
National Parkinson Foundation Care Center
Albuquerque, New Mexico
Movement Disorder Clinic - Deer Lodge Centre
Winnipeg, Manitoba, Canada
Bellevue Center for Parkinson
and Other Movement Disorders
New York, New York
Colorado Neurological Institute
Movement Disorders Center
Englewood, Colorado
Parkinson’s Disease and Movement
Disorders Center of Boca Raton
Boca Raton, Florida
Notre Dame des Secour Hospital, Parkinson
Memory & Movement Disorders Center
Byblos, Jbeil, Lebanon
Plummer Movement Disorders Center
Scott & White Clinic /
Texas A&M Health Science Center
Temple, Texas
Booth Gardner Parkinson's Care Center
Kirkland, Washington
Regional Parkinson Center
at Aurora Sinai Medical Center
Milwaukee, Wisconsin
Parkinson's Clinic of the Ozarks
Springfield, Missouri
NPF OUTREACH CENTERS
The National Parkinson Outreach Center
at Florida Atlantic University
Boca Raton, Florida
Lee Memorial National Parkinson
Foundation Outreach Center
Fort Myers, Florida
Parkinson Association of Southwest Florida
Naples, Florida
Florida Hospital Neuroscience Institute
Parkinson Outreach Center
Orlando, Florida
Tallahassee Memorial Parkinson's Outreach Center
Tallahassee, Florida
Nevada Neuroscience Foundation
Henderson, Nevada
The Comprehensive Movement Disorders
Center, University at Buffalo
Depts. Of Neurology/Neurosurgery
Buffalo, New York
Parkinson's Resources of Oregon
Portland, Oregon
Parkinson Foundation of
the National Capital Area
McLean, Virginia
NPF Chapters
NPF seeks to be a uniting force in the Parkinson community, one in which the organization at large, its Centers, and a grassroots
Chapter network form an integrated system. Chapters have an important role as local and regional partners of NPF in identifying
needs and helping deliver access to the right care, information, and support. NPF seeks to assist Chapters in increasing their
capacity to serve their communities, thereby maximizing quality of life as needs change throughout the course of the disease.
Arizona Chapter of
the National Parkinson Foundation
Phoenix, Arizona
Parkinson Network of Arizona
Phoenix, Arizona
Kingdor National Parkinson Foundation
Nassau, Bahamas
Los Angeles Alliance Against Parkinson's Disease
Los Angeles, California
National Parkinson Foundation –
Orange County Chapter
Newport Beach, California
Parkinson Association of Northern California
Sacramento, California
Parkinson Network of Mount Diablo
Walnut Creek, California
Colorado Parkinson Foundation
Colorado Springs, Colorado
Northeast Parkinson’s and Caregivers
Middletown, Connecticut
South Palm Beach County Chapter of the NPF
Boca Raton, Florida
The Park Optimists
Coral Gables, Florida
Norcal NPF Chapter
Redding, California
21
NPF Chapters
(continued)
Parkinson Association of Southwest Florida
Naples, Florida
Parkinson Association of Minnesota
Plymouth, Minnesota
Southeast Parkinson Disease Association
Orlando, Florida
Parkinson's Group of the Ozarks
Springfield, Missouri
Parkinson Association of Greater Daytona Beach
Ormond Beach, Florida
Brooklyn Parkinson Group
Brooklyn, New York
St. Augustine Parkinson's Disease Support Group
St. Augustine, Florida
Parkinson’s Support Group of Syracuse New York
Clay, New York
North Florida Parkinson Awareness Group
Tallahassee, Florida
Parkinson’s Association of Western New York
Depew, New York
Alzheimer/Parkinson Association
of Indian River County
Vero Beach, Florida
Parkinson's Support Group of Upstate New York
Rochester, New York
Midwest Parkinson's Awareness of Northeast Ohio
Alliance, Ohio
Central Savannah River Area (CSRA)
Parkinson Support Group – Augusta Chapter
Grovetown, Georgia
Parkinson's Resources of Oregon
Portland, Oregon
Northwest Georgia Parkinson Disease Association
Rome, Georgia
The Parkinson Council - Philadelphia Chapter
Bala Cynwyd, Pennsylvania
Parkinson’s in the Park
Springfield, Georgia
Lehigh Valley Parkinson Support Group
Bethlehem, Pennsylvania
Hawaii Parkinson Association
Honolulu, Hawaii
The Parkinson Chapter of Greater Pittsburgh
Pittsburgh, Pennsylvania
Parkinson Association of Illinois
Chicago, Illinois
Asociacion Puertorriqueña de Parkinson
Carolina, Puerto Rico
Parkinson Foundation of the Heartland
Overland Park, Kansas
Fundacion Puertorriqueña de Parkinson
San Juan, Puerto Rico
Northeast Kansas Parkinson Association
Topeka, Kansas
Eljay Foundation for Parkinson Syndrome Awareness
Lake Charles, Louisiana
Cape Cod Chapter of the National
Parkinson Foundation
East Dennis, Massachusetts
Parkinson's Association of West Michigan
Grand Rapids, Michigan
Parkinson Association of South Dakota
Sioux Falls, South Dakota
Parkinson Foundation of the National Capital Area
McLean, Virginia
Parkinson Educational Society of Puget Sound
Olympia, Washington
Wisconsin Parkinson Association
Milwaukee, Wisconsin
Together with ongoing funding for and support of leading-edge
research efforts, our many programs and services are the
forefront of fighting back and moving forward.
From training health providers and allied health professionals to
better initiate and integrate care, to providing an exceptional
range of public information, to fostering innovative outreach
efforts in the community, NPF brings tools, talent and inspiration
to all those living with and striving against Parkinson.
NPF PROGRAMS
and SERVICES
PROFESSIONAL EDUCATION
ALLIED TEAM
TRAINING FOR
PARKINSON (ATTP)
Charting a new course in
quality health care delivery
Allied Team Training for Parkinson (ATTP) is an
intensive four-day, team-based national training
initiative for allied health professionals – designed to
improve interdisciplinary care in Parkinson disease.
ATTP has been recognized by the U.S. Department
of Health and Human Services as a “stellar program”.
23
COMMUNITY
OUTREACH
A commitment to developing appropriate services
for all communities is evidenced by NPF’s requirement that every designated Center be actively
involved in facilitating access to education, support
and comprehensive care. NPF believes in “access
for all,” so that every family affected by Parkinson
disease is able to find the right services at the right
time – services that are meaningful to the individual
and the community at large. Outreach strategies
include thoughtful and active collaboration with
diverse, underserved urban and rural communities.
COMMUNITY
PARTNERS FOR
PARKINSON CARE
(CPP)
CPP, partially
funded through
a grant from
the Medtronic
Foundation, is
NPF's "learning
lab" for how to
most effectively
build partnerships for outreach to diverse and rural communities.
CPP is a national outreach initiative, focused on
the development of partnerships to create innovative
strategies for overcoming the cultural, language,
geographic and health barriers that limit access to
education, support and comprehensive care in
Parkinson disease.
Regional coalitions are established between NPF
Centers and affiliate Chapters as well as local agencies
and community leaders; there are seven coalitions
operating in cities and rural areas across the country.
TEXAS VOICE
PROJECT FOR
PARKINSON DISEASE
This Dallas-based non-profit organization operates under the
auspices of the National Parkinson Foundation and is dedicated
to helping people with Parkinson disease regain and maintain
their ability to communicate.
The Texas Voice Project represents the "gold standard" in the
treatment of Parkinson-related voice disorders. Its certified
speech-language pathologists employ the Lee Silverman Voice
Treatment LSVT®, a four-week, intensive speech therapy
program. Patients are subsequently enrolled in an on-going
maintenance program called The LOUD Crowd, which includes
monthly group sessions, 6-month re-evaluations, a singing
program and special events, such as speech contest, parties and
excursions where patients practice the communication skills they
have regained. The Project’s emphasis on maintenance activities
is unique in the country. No Parkinson patient in Texas is
turned away because of an inability to pay.
INFORMATION SERVICES
Access to the latest information on Parkinson disease, its treatment,
and access to care is critical for affected families. e National Parkinson
Foundation stands as the major clearinghouse for information regarding
all aspects of the disease. e sheer volume of inquiries and requests is
evidence of the high value that the greater Parkinson community places
on these services. Information is provided through many
channels, from print to the Internet.
The Parkinson
Education Series –
over 200,000
copies distributed
annually free of
charge.
CENTER AND
CHAPTER LEADERSHIP
CONFERENCES
CONFERENCES
Center Leadership We look forward,
each year, to meeting with our NPF
network of medical directors, center
coordinators and other health care
professionals at our Center Leadership
Conference. In 2006, our “Collaboration for Care” Conference was held
in Chicago. We discussed the latest
research findings in Parkinson care;
non-motor dysfunction and the issues
and challenges of interdisciplinary
team development. The meeting
was attended by 105 health care
professionals and leaders from the
U.S. and Canada.
5TH ANNUAL YOUNG-ONSET
PARKINSON NETWORK CONFERENCE
Chapter Leadership The Chapter
Leadership Conference was held in
Orlando, Florida, at which 67 representatives from the NPF Chapter
network gathered to share and learn
from each others experiences. Attending to requests received from several
Chapters, we emphasized the topics of
Board development and fundraising,
in order to help chapters meet local,
regional, and national needs.
An excellent program provided education and networking
opportunities for all who attended. Topics ranged from groundbreaking recent scientific research, to legal workplace and financial
issues, to sessions on yoga, music and pet therapy. Breakout sessions
were divided into dedicated tracks, including one designed to
address carepartner needs and concerns.
July 5-7, 2007 | Chicago, Illinois
This year, the Windy City stirred up the largest YOPN conference
to date, with over 400 in attendance. This annual conference has
become the “must attend” event for all those affected by YoungOnset Parkinson disease.
The creative conference committee was led by Chair Mark Rubin
(Chicago), and included Jackie Bodie, (Calgary, AB, Canada);
Todd Bischoff (California); past co-chairs Angela and Karl Robb
(Virginia); James Trussell (Georgia); Diane Breslow, Center
Coordinator at Northwestern Memorial Hospital, (Chicago, IL)
and Adolfo Diaz, NPF Field Services Manager (Miami FL).
Lonnie Ali, wife and care partner of three-time world heavyweight
champion Muhammad Ali delivered the keynote address, further
emphasizing the importance of caregiving. Lonnie also participated
in a breakout session, where she candidly and graciously discussed
the challenges faced by care partners and persons with Parkinson.
Her advice was “to learn everything you can about the disease...
and keep a positive attitude.”
Key portions of the conference may be viewed by visiting NPF
online at www.parkinson.org. Look for the link titled: 5th Annual
YOPN Webcast.
25
2006-2007 Events
Another year of
fabulous ideas for
raising funds for
Parkinson research,
from communities
across the country
Many people raise money and awareness
for the National Parkinson Foundation
through innovative community and
special event fundraisers, as well as gifts
of proceeds from products. We are always
grateful for this support, and always
impressed with the energy and creativity
that fuels it. Here are just a few examples:
MATT
LANGAN’S
TREK KIN
FUNDRAISER
BRENNAN DATES
SHAKES, RATTLES,
AND ROLLS TO
FIND THE CURE
February 17-21, 2007
November 2006–October 2007
While many of his classmates were sunning on a
beach or at the very least sleeping late, Matt Langan –
an 18 year old freshman at Washington and Lee
University – was pedaling almost 400 miles into a
cold breeze to raise money and awareness for the
National Parkinson Foundation. Matt conceived of
this fundraiser after learning that a close family friend
had recently been diagnosed with Parkinson disease.
He ended up raising $12,000 to support the cause.
Some people will go to extremes to make a point.
When Brennan Dates learned that a close family
member was diagnosed with Parkinson disease, he
made the decision to Shake, Rattle, and Roll from
Miami to Argentina – and back – on his trusty
BMW motorcycle to attract people’s attention to
the seriousness of this disease and the urgent need
to find a cure. Brennan says that the adventure was
life-affirming. It also raised $43,735 for PD research.
THE 50TH ANNUAL
INTERNATIONAL GALA FOR HOPE:
ALL THAT GLITTERS IS GOLD
National Parkinson Foundation celebrated its
50th Annual International Gala for Hope on
February 10, 2007 at the JW Marriott in Miami.
The ballroom was transformed into an All That
Glitters is Gold themed evening as more than
385 guests enjoyed great music, dancing, delicious
food, and a silent and live auction. Attendees
included members of NPF Chapters and Centers
of Excellence from all over the country including
the Bahamas and Canada.
May 12, 2007
EVENTS
A SPRING
WEDDING
HONORS
FAMILY
MEMBERS
DAUGHTER &
FRIENDS RUN
WILD TO RAISE
FUNDS IN THE
NAME OF A
SPECIAL NPF
VOLUNTEER
April, 2007
Californian newlyweds Heather Brandt and
Steve Paolo marked their special day by
making a contribution to National Parkinson
Foundation in honor of several relatives who
are living with Parkinson disease.
Their message to their guests: “Neurological
diseases, including Parkinson, have unfortunately had a huge effect on both of our families.
As we take this step together to start our own
family, we know that such diseases will
continue to affect us. We decided it would be
fitting to include NPF in our wedding
celebration to help those who are dedicated
to helping families like ours.”
After years of selfless volunteer work for NPF,
Laura Yazdian’s father, Marty Ardman, was
himself diagnosed with PD. And all those who
love him were motivated to help – somehow.
Laura decided to organize a team to run the
Nashville Half-Marathon, using the tools in
the “Community Fundraising” section of
NPF’s toolsite to manage their fundraising
efforts. The result was nothing short of
spectacular: to her great amazement – and
satisfaction – Team “Running Wild” raised
almost $13,000 for National Parkinson
Foundation. Not to mention raising Marty’s
spirits immeasurably.
“If you haven’t any charity in your heart,
you have the worst kind of heart trouble.”
BOB HOPE
27
Honor Roll
2007
Thank
You!
NPF AMBASSADORS
The Ambassadors represent cumulative
giving of $100,000 and above. All of
our Ambassadors are recognized with
a gift of a hand-blown glass caduceus
designed especially by the noted artist,
Frabel. It represents the ancient Greek
symbol of the medical profession and
exemplifies our goal to fund the most
innovative research worldwide, in order
to find the cure for Parkinson disease.
“Learn from yesterday,
live for today, hope for
tomorrow. The important
thing is not to
stop questioning.”
ALBERT EINSTEIN
Harriet Rubens
Sam J. Sanfilipo
B. J. Shortridge
Sven Siemen
Alan M. Slewett
Nathan Slewett
Sheila Slewett
SmithKline Beecham
Donald Soffer
South Palm Beach County
Chapter of NPF
Southern Illinois University
Estelle Stern Spiegel
State of Florida
Stearns Weaver Miller Weissler
Alhadeff & Sitterson, P.A.
Senator Paul B. Steinberg
Martin Tuchman
Norma Gilbert Udall
University of Kansas
Medical Center
Robert Van De Wetering
Jack Weiss
Wisconsin Parkinson Association
Bruce & Kathy Wisnicki
Mitchell Wolfson
Gladys Wollowick Foundation
Monty Yokel Charitable Lead Trust
Phillip Youtie
Herbert C. Zemel, Esq.
The William Zimmerman Foundation
Margot Zobel
29
HONOR ROLL
E. Richard Alhadeff, Esq.
Allied Signal Foundation
Leo Amoroso
Beth Israel Medical Center
Edna Boddy
Boehringer Ingelheim
Pharmaceuticals Inc.
James Cayne
Ruth Niggel Chinowth
Kari Clark
Richard Clark
Robert Collins
Community Health Charities
of California
of Florida
Dorothy Coogan
Hon. Irving & Hazel Cypen
Lynn Diamond
Dow Chemical Company
Dupont Merck Pharmaceuticals
Company
Elan Pharmaceuticals, Inc.
Donald Fine
The Five Millers Family Foundation,
Inc.
Charles H. Gehret
Rollin M. Gerstacker Foundation
GlaxoSmithKline Foundation
Dr. Moses & Beatrice Goodman Fund
The Greenburg-May Foundation, Inc.
Albert Greenfield
Harold and Jean Grossman
Family Foundation
Health Resources and Services
Administration
Abel Holtz
Dolores Hope
The Don A. Hunziker
Family Foundation, Inc.
Edythe Kay-Marsa
Barry Kaye Associates, Inc.
Bawa and Kamal Khindri
Eugene and Rose Kleiner
Family Foundation
Heinrich Kolbel
Marjorie & Irvin Korach
Harold P. Kravitz
Charlotte La Posea Foundation
Ira M. Levenshon
Roger Levin
Edwin Levy
Janet Malamud
Neil Mangot
Stanley W. Marion
Isabel May
Erna Mayer
Medtronic
Medtronic Foundation
Alan B. Mirken
Alan B. & Barbara Mirken
Foundation
Manuel & Mercedes Mosteiro
Novartis Pharmaceuticals Corporation
NPF Orange County Chapter
Jo Ann Pepper Oreffice
Paul F. Oreffice
The Oreffice Foundation
W. James Orovitz
The Parkinson Alliance
Parkinson Chapter of
Greater Pittsburgh
The Parkinson Council
Parkinson Disease Foundation
Parkinson Foundation of the National
Capital Area
Parkinson’s Unity Walk
Vivienne Parness
Pharmacia Corporation
Roche Laboratories
Marion A. Roletti Foundation, Inc.
Norman Rothman
The Rothman Foundation
NPF FOUNDERS
HONOR ROLL
The Founders represent cumulative
giving of $50,000 to $99,999. All of
our Founders are recognized with a gift
of an authentic, scientific microscope
encased in glass. This is a symbol of our
continuous quest to find the cause of
and cure for Parkinson disease.
Allstate Giving Campaign
Carlos Arboleya
A. Jeffrey Barash
Harold Beck
Stephen & Mary Birch
Foundation, Inc.
The Braeside Foundation
Daniel D. & Erhla Cantor
Caruthers Foundation, Inc.
Harry Wayne Casey
J. Doreen Chadbourne
Colorado Parkinson Foundation, Inc.
Community Foundation for Palm
Beach and Martin Counties
Community Health Charities of
Maryland
the National Capital Area
Community Health Charities of NY
Pennsylvania
Community Health Charities of Texas
Robert A. M. Coppenrath
Robert M. Cornfeld, D.M.D.
Millard M. Cummins
Ann Degraff
Selma Denburg
Diamond Creek Vineyards
Ralph & Barbara Edwards Family
Foundation
Gail Epstein
ESSAR Family Foundation
The Evenor-Armington Fund
Fabre Kramer Holdings, Inc.
Stecia Feldman
Fidelity Charitable Gift Fund
Vain & Harry Fish Foundation, Inc.
Doree Fromberg
Ronald Galowich
Gladys Gelb
Martin J. Gelb
Irene Goldman
Carol Greenberg
Alice Greenberg Memorial
Philanthropic Fund
Jerry Haar
Richard Hacker
Edward F. Harris
Mel Harris
Hello Shops
Elmer Hurwitz
IBM Corporation
Lieba Ingber
Deane Jacques
John & Evelyn Kossak
Foundation, Inc.
Carol Landa
Michael L. Landa
William Landa
Abraham Lieberman, M.D.
Jerry Lindzon
Lois Marcus
Merck
David Meyer
Robert Mitchell
Michael Mulroy
National Voluntary Health
Calvin & Flavia Oak Foundation Inc.
Park Foundation, Inc.
Parkinson Association of
South Dakota
Parkinson Education Group
Parkinson Foundation of
the Heartland
Paxson Communications Corporation
Pfizer Inc
The Pratt Family Foundation
The Ridgefield Foundation
Ralph B. Rogers Foundation
Billy Rose Foundation, Inc.
Quiet Harbor Trust Agency
Arthur Rosewall
Carolyn Roskin
The Roth Fund
SE Pennsylvania United Way
Savage Trichter Ink, Inc.
Lawrence Schine
The Schwarz Pharma Foundation
Louella Shapiro
George Simon
Carol Soffer
Rita Soffer
Somerset Pharmaceuticals Inc
Jerry & Emily Spiegel
Family Foundation
Ruby Stevens
Richard B. Stolley
Amancio Suarez
Betty Taylor
Teva Neuroscience
Phillip Traub
United Way of Miami-Dade County
Vanguard Charitable Endowment
Program
Harry Vermeer Family Foundation
Vernalis Pharmaceuticals, Inc.
Dennis C. Wallach
James H. Warsaw
Harry Weinberg Family
Foundation, Inc.
Michael L. & Antoinette H. Wilkerson
Charitable Remainder Unitrust
Allan Yarkin
Isaac Zelcer
THE PRESIDENT’S
SOCIETY
The President’s Society represents
cumulative giving of $25,000 to
$49,999. The President’s Society
recognizes the philanthropic efforts
of individuals, foundations,
corporations and affiliate chapters.
Rene & Irene Abel
The AME Foundation, Inc.
Anonymous
Acadia Pharmaceuticals
American Fence Corporation
Amgen
Eugene M. Bane Charitable Trust
Ronald Barnette
Virginia Barrett
David & Joan Bartholomew
Rhoda Bernstein
Hollis Hall
Mary Hampton
Hawaii Parkinson Association
Chapter of NPF
Lawrence Hoffheimer
Illinois Council of Voluntary
Health Agencies
J.A.M. Anonymous Foundation, Inc.
Jewish Communal Fund
S. Johns
Beulah Jones-Mitchell
Nina & Stephen Joyce
Eleanor Kass
Walter Kirk
Robert Koch
Ronald Krancer
Kyowa Pharmaceutical, Inc
James Annenberg La Vea
Charitable Foundation
David Laventhol
Laurence W. Levine Foundation, Inc.
Philip B. Lowy
Mastronardi Foundation
Robert Matthews
Mellon Private Trust Company
Merriman Family Foundation
Elizabeth Miedema
Nancy Mulheren
Anna Nalbandian
National Health Agencies
Agencies of Ohio
Neurim Pharmaceuticals
Northern Trust Bank
Paul Novelly
The Ohio State University
Sylvia Orkin
Parkinson Association of Minnesota
Parkinson Association of
Northern California
Parkinson Association of Southwest
Florida, Inc.
Parkinson's Support Group
of Upstate NY, Inc.
Lowell W. Paxson
Peacock Foundation, Inc.
People Drug Store
David & Kelli Phillips
Margot & Thomas J. Pritzker
Family Foundation
Albert Quentel
Mirta Reina
Josephine Resch
Emma Rovelli
Sacramento Area United Way
St. Joseph’s Hospital and
Medical Center
Irwin Samuels
A. J. Schlossman Foundation Trust
Schwarz Pharma, Inc.
Elizabeth Scrivner
Erich Segal
William Shepherd
Irving S. Sherr
Lisa Shulman
Harry S. Sloane Foundation
Margaret Smartt
Gary Smolin
Joan Stanton
C. Stegink
Lucille Stephens
The Studley Family Foundation
Brad Sympson
T.D. Waterhouse
Marjorie Tallman Educational
Foundation Trust
Vincent Tese
The Thoresen Foundation
Titan Pharmaceuticals, Inc.
Jacqueline and Robert H. Traurig
UCB, Inc.
United Way of Southeastern
Pennsylvania
University of Miami Leonard M.
Miller School of Medicine
Alberto Vadia
Sarah Vanderweele
Wang Associates
H.E. and Helen R. Warren
Foundation
Shirley Weaver
Wellness Health Pharmaceuticals
The Dr. Jack Widrich
Foundation, Inc.
James B. Williams
Louis G. Zimmerman
31
HONOR ROLL
Chaikovsky Charitable Fund
Hannah S. and Samuel A. Cohn
Memorial Foundation
Community Foundation for the Fox
Valley Region
Community Foundation of the
National Capital Region
Alabama, Inc.
Georgia
Kansas
Massachusetts
Missouri
Tennessee
Virginia
Cortex Pharmaceuticals, Inc.
Robert & Joanne Crown
Income Charitable Fund
CSRA PD Support Group
M. Dalitz
DEARS Foundation, Inc.
Hedy Des Jardins
Stella Drullinger
Harry S. Dube Foundation
Pauline Dunning
Robert & Charlotte Dyment
Family Trust
Eisenhower Medical Center
Walter & Anita Farrell
Ruth Featherstone
FedEx Services
Elaine Fellowes
Merrill Fenner
Rose Forman
Gaines Unitrust
Jacques Gale
Gardens Parkinson's Support Group
Georgetown University Hospital
Alvin Gibbs
Pauline Allen Gill Foundation
GlaxoSmithKline
David B. Golub
Rhoda Goodman
Ana-Maria Fernandez Haar
THE GUARDIAN SOCIETY
HONOR ROLL
The Guardian Society represents
cumulative giving of $10,000 to
$24,999. The Guardian Society
recognizes the philanthropic efforts
of individuals, foundations,
corporations and affiliate chapters.
Acacia Charitable Foundation
Herbert Adair
Adorno & Zeder Community
Care Fund
AK Steel Foundation
Larry & Anne Alexander
Edward Allen
Allen & Company LLC
Don Allen Foundation
Rick Alterman
Jack & Sylvia Altman Foundation,
Inc.
Associate Member Council
Athletes With Heart
Atlas Welding Boiler Repair
Avanir Pharmaceuticals
Juana Avila
Ruby Bacardi
Dorothy Ball
John E. & Nellie J. Bastien
Memorial Foundation
The Batchelor Foudation, Inc.
Baylor College of Medicine
Benevolent & Protective Order
of Elks
Moises Berezdivin
Norma Berman
Ivalee Berry
Leonard Bielski
Thomas E. Blackburn
Eugene Blankenship
Joaquin Blaya
Albert Blenderman, M.D.
The T & M Bollt Family Foundation
Jimmie Bonbright
Braman Family Foundation, Inc.
Lois Brounell
Nina & Joe Brown
The Brunetti Foundation
Buehler Family Foundation
Marshall Burack
Lottie Burch
Burfeind Foundation
Burgess Snyder Industries
Franco Burini
CT Management
Jean Cadieux
Mardelle Cagen
The Callans Family Foundation
Bernard Caplan
Leonard Cargan
Carmen Cartaya
Dorothy Cassett
Cast North America Inc
Rosa Castillo
Chartwell Foundation
Daniel Chiodo
Warren G. & Theresa L. Christianson
Coastal American Corporation
Mary Cofrin
The Manny & Ruthy Cohen
Foundation, Inc.
Toby Cohn
James & Margaret Coleman
George Collins
Communities Foundation of Texas
The Community Foundation of
Sarasota County
Colorado
Community Health Charities Of
Michigan
New Jersey
North Carolina
New Mexico
Community Health Charities of Ohio
South Carolina
Utah
Washington
Continental Co.
Coopers & Lybrand
D D Dunlap Companies
Dade Community Foundation, Inc.
Greg Decoteau
Deloitte & Touche
Angeline Dent
Bill Desser
Carl & Roberta Deutsch Foundation
Fred Diamond
Roderick Dickinson
The Diller-Von Furstenberg Family
Foundation
F. Dixon
Fred Doolittle
Paul Dunn
Dupont De Nemours
Dyson Foundation
Eaton Foundation
Eli Lilly
Eljay Foundation for Parkinson
Awareness, Inc.
Equitable Holding
Ross Evans
Frank Evarone
Libby Fain
Gerry Fantle
Mary J. Fay
FedEx Freight East, Inc.
Judith Feldman
Ferkauf Foundation
Robert P. Fetch
Dorothy Fink
Fireman's Fund Insurance Company
Robert Fiske
Bernard J. Fogel. M.D.
Arnold Frank
The Harry and Flora D. Freund
Memorial Foundation
Friars National Association
Foundation
Alice E. Fulop
Charles Ganz
Gap Foundation Gift Match Program
James J. and Joan A. Gardner Family
Foundation
Gateway Care, Inc. Foundation
Genzyme Tissue Repair
Raymond Gertz
Marilyn & Myers Girsh
Robert Glaze
Isabelle Goldenson Association
“There is hope in dreams, imagination,
and in the courage of those who wish
to make those dreams a reality.”
JONAS SALK
William Hill
Gordon Hoerauf
James Holmes
Daniel Holtz
Dennis Honzay
The Bob and Dolores Hope
Charitable Foundation
B. Hopper
David C. Horn
The Laura or Walter Hudson
Foundation
Independent Charities of America
Industrial Bowling Corporation
Bill Ingram
Barry Jackson
Jewish Community Foundation
of Metrowest
Milton Jimenez
Johnson & Johnson
Charles Jones
Donald and Sally Jones
Robert C. Kagle
Gabriel Kain
The Sidney & Pearl Kalikow
Foundation
The Kaltman Family Foundation
Keenan Antiques
Bernard Keeshan
Eugene Kessler
Martha McCarty Kimmerling
Eugene C. Kincaid Living Trust
Kingdor NPF Bahamas Chapter
Elmer Kinnamon
Kintera, Inc.
Kitsap County United Way
Lawrence & Arlene Klainer
Mildred Klindworth
33
HONOR ROLL
Arlene & Arnold Goldstein
Family Foundation
Lawrence Golub
Martha Gordon
Gloria Gorelik
Julianne Grabert
Great Western Bank
Greater Cincinatti Foundation
Greater Miami Jewish Federation
The Alan C. Greenberg
Foundation, Inc.
Greystone Foundation
Reuben A. & Lizzie Grossman
Foundation
Laura Gruy
Bill Guthy
Tom Hacker
Ruth Hagestuen
HPC Incorporated
Margaret Hahn
Fred Hallman
Stacey Halpern
David Hamburger
Sydney L. Hammer Living Trust
Gary N. Handis
Frances Handler
Monness Hardt
Michael Harkins
Harmony Baptist Church
Fran Harris
The Healthfund of Minnesota
Florence Hecht
Monnica Heftler
Susan Henry
Robert Herzog
Herbert Hess
Hialeah Hospital
Gesley Knickerbocker
Harry Korman
Irwin Kott
Harry Kramer Memorial Fund
Mysak Kravitz
Rod Kvamme
Lawrence County Parkinson’s
Association
Bruce Layne
Yvonne Lenart
Sachiko M. Lenk
The Lennar Foundation, Inc.
Polly Annenberg Levee
Charitable Trust
A. S. Levendosky Living Trust
Shayla Shabot Levy Foundation
Marilyn Lewis
Michael and Kathy Lewis
Douglas Liebhafsky
Lorber Family Foundation
Arthur Loux
Robert Love
Craig N. Lowe
James Lyons
Marathon Sports
Ruben Matz
Bernard Mayers
Manuel Medina
Millicent Medvied
Luis Mendoza
Julia and Gilbert Merrill Foundation
Sara S. Meyer
Miami Jewish Home & Hospital
for the Aged
Microsoft Giving Campaign Program
Gail Milhous
Dora Miller
Lester Miller
Michael Miller
Joseph Millimet
Harvey Mininberg
Nicholas Minnucci
Robert Moffett
Sarah Moreno
Morgan Stanley UK Group
HONOR ROLL
Morrison, Brown, Argiz & Farra, LLP
Mother Lode Parkinson Foundation
Mt. Vernon Knights of Columbus
Club, Inc.
Helen Murin Foundation
G. Murray
Stephen Muss Foundation
Mylan Bertek Pharmaceuticals Inc.
N.E. Kansas Parkinson Foundation
National Philanthropic Trust
National Voluntary Health of
Arkansas
National Voluntary Health of
Colorado
National Voluntary Health Illinois
National Voluntary Health Michigan
Pennsylvania
Morton Neufeld Foundation
New River Communications
Rosalyn Newman Foundation
Julia Newton
The Niewig Foundation
North Carolina National Voluntary
Health
North Ridge Medical Center
Northwest Pipe Company
Onan Family Foundation
Aggi Oschin
Ostern Foundation
The Oxley Foundation
Pacific Coast Cutting Horse
Association
The Beatrix & Martin Padway
Foundation
Palm Desert Travel
Chris Papazickos
Golda Peterson
Lanny Peterson
Pipevine, Inc.
Martin Polonsky
John Pope
Victor Posner
George Powell
R Foundation
William Ray
Margaret Rella
Greg & Stacey Renker
Dane Reynolds
Judith Richard
Richard Riddell
Riverside Medical Foundation
Robert T. Rolfs Foundation
Roseland Post #49,
American Legion Corporation
Cecil Rosen Foundation
Rosenthal Foundation
Hubert Rosomoff
Martin Ross
Regina Rubenstein
John Russo
Thomas A. Ryan
Cynthia Sandusky
Eric Schaffer
Liz Schaub
Jeffrey H. Schecter
Meryl Schwartz
Sherwood Schwartz
Robert Schweitzer
Joelle E. Scott
Harriette Secrest
Alan L. Seely
Karen Segal Foundation
Kimberly & Matthew Seidman
Patricia Shapiro
Everett Sharp
Donald A. & Virginia D. Sillers
Marty & Dorothy Silverman
Foundation
Leon Simkins
James Sloss
Edward W. Smith Jr. Foundation
Smurfit Latin America
Solomon Family Foundation
Enrique Sosa
Linda Sotnick
Southern Wine & Spirits
Dale Speck
Fritz Sperling
Daniel J. Spiegel Family Foundation
Sam Spiegel Foundation
Sprint
John Spurlino
Albert Staton
Norman Stein
Gary Stevens
W. L. Strelow
Franklin Surnamer
Nancy Swenson
Marian L. Tansky
Melvin S. Taub
Avis Taylor
John Taylor
Tenet
Nina N. Thayer
Bill Torrance
Tristar Martial Arts Academy, Inc.
Tuchman Foundation
Ueberroth Family Foundation
Union Planters Bank
United Way of the Bay Area
United Way of Kitsap County
United Way of Tri-State
University of Colorado
University of Pittsburgh
Valeant Pharmaceuticals International
Jay & Betty Van Andel Foundation
Ben Van De Bunt
Helen Vanderhoff
Jenni Vigar
Millie Viqueira
Arleen Wahrman
James H. Warsaw Foundation to
Cure Parkinson’s Disease at
The Giving Back Fund
Watson Laboratories
Marvin Weber
William Weiner
Bernice Weinstein
Millicent Weinstein
Irving J. Weiss Revocable Living Trust
Dotha Welbourn
Jean L. West
Dan C. Whitehurst
S. Z. Wiener
Edwin Willinger Charitable Trust
Richard Worsley
John Wright
Wynanda Ltd
Clarence Youngren
Tanya Zallea
Gregg Zaun Charitable Foundation
ARGIZ & FARRA, LLP
MORRISON, BROWN,
c Accountants
Certified Publi
LIC
NDENT CERTIFIED PUB
REPORT OF INDEPE
ACCOUNTANTS
s
To the Board of Director
ion, Inc.
National Parkinson Foundat
of the National Parkinson
ments of financial position
nying consolidated state
consolidated statements
mpa
ted
acco
rela
the
the
ted
and
audi
6,
We have
2007 and 200
l
undation”) as of June 30,
se consolidated financia
“Fo
The
d.
(the
ende
Inc.
ion,
then
s
ndat
year
Fou
for the
ess an
and functional expenses
responsibility is to expr
Our
ent.
agem
of activities, cash flows
man
s
bility of the Foundation’
statements are the responsi
based on our audits.
ated financial statements
opinion on these consolid
United States of
s generally accepted in the
ce with auditing standard
assurance about
rdan
le
acco
onab
in
ts
reas
in
audi
obta
our
to
d
t
We conducte
orm the audi
ire that we plan and perf
An audit includes
requ
ent.
s
dard
tatem
stan
miss
se
l
eria
Tho
a.
Americ
free of mat
l
financial statements are
in the consolidated financia
whether the consolidated
amounts and disclosures
e
s, evidence supporting the
significant estimates mad
and
used
es
cipl
prin
ng
examining, on a test basi
unti
eve
includes assessing the acco
ment presentation. We beli
statements. An audit also
consolidated financial state
as evaluating the overall
by management, as well
ion.
opin
reasonable basis for our
that our audits provide a
all material respects,
to above present fairly, in
financial statements referred
its net assets and its
in
ated
ges
olid
chan
cons
the
the
and
ion,
and 2006
In our opin
ndation as of June 30, 2007
rally accepted in the
Fou
gene
the
of
es
cipl
tion
prin
posi
l
ng
ncia
unti
the fina
with acco
then ended in conformity
cash flows for the years
a.
United States of Americ
, 9th floor
1001 Brickell Bay Drive
Miami, Florida 33131
00
73-55
305-3
Tel:
Fax: 305-373-0056
The following pages
were extracted from
the audited financial
report of the National
Parkinson Foundation.
The complete accompanying notes are an
integral part of those
financial statements.
A copy of the full audit
report is available from
the Finance Department,
1501 NW 9th Ave.,Miami,
FL 33136.
Miami, Florida
September 13, 2007
www.mbafcpa.com
Financial
Report
, 5th floor
301 East Las Olas Blvd.
33301
Ft. Lauderdale, Florida
00
60-90
954-7
Tel:
Fax: 954-760-4476
502
1113 Spruce Street, Suite
2
Boulder, Colorado 8030
50
81-25
303-3
Tel:
Fax: 303-381-2551
145
151 Southhall Lane, Suite
Maitland, Florida 32751
80
60-60
Tel: 407-6
Fax: 407-660-6079
NPF 2007 Spending by Category:
Fundraising
Research
Management
& General
12%
5%
39%
Patient
Care
30%
14%
Public
Education
As illustrated by this chart,
directed more than 83% of its
2007 spending on areas related
to its core mission (research,
patient care, and public
education) – and less than 17%
on fundraising and management/general combined.
35
NATIONAL PARKINSON FOUNDATION, INC.
CONSOLIDATED STATEMENTS OF FINANCIAL POSITION
June 30, 2007 and 2006
ASSETS
2007
$
Cash and cash equivalents
FINANCIALS
1,220,974
556,621
227,260
133,938
388,028
240,205
1,000,000
262,036
86,057
22,309,685
537,240
86,088
25,392,655
606,658
$
27,188,164
TOTAL ASSETS
$
3,337,363
Receivables:
Pledges, net of allowance and unamortized discount of
$386,508 and $343,477 for 2007 and 2006, respectively
Charitable trusts
Estate receivable
Other receivables
Prepaid expenses and other assets
Investments
Property and equipment, net
2006
$
29,196,644
LIABILITIES AND NET ASSETS
$
Accounts payable and accrued expenses
Grants payable
Annuities payable
$
411,802
124,210
856,674
376,400
87,225
846,126
1,392,686
1,309,751
Net assets:
Unrestricted
Temporarily restricted
Permanently restricted
18,589,299
5,428,789
1,777,390
21,695,143
4,414,360
1,777,390
TOTAL NET ASSETS
25,795,478
27,886,893
TOTAL LIABILITIES
COMMITMENTS AND CONTINGENCIES
TOTAL LIABILITIES AND NET ASSETS
$
27,188,164
$
29,196,644
CONSOLIDATED STATEMENT OF ACTIVITIES
Year Ended June 30, 2007
----
Temporarily
Restricted
Permanently
Restricted
1,649,644
117,515
-
-
481,137
274,740
721,692
2,130,357
821,151
72,250
(3,829)
(821,151)
-
481,137
274,740
793,942
2,126,528
-
11,580,460
1,014,429
-
12,594,889
Expenses and losses:
Program services:
Research
Public education
Patient care services
4,397,630
2,035,833
5,753,889
-
-
4,397,630
2,035,833
5,753,889
Total program services
12,187,352
-
-
12,187,352
Supporting services:
Management and general expenses
Fund raising
706,134
1,777,896
-
-
706,134
1,777,896
Total support services
2,484,030
-
-
2,484,030
14,671,382
-
-
14,671,382
14,922
-
-
14,922
14,686,304
-
-
14,686,304
Change in net assets
(3,105,844)
1,014,429
-
(2,091,415)
Net assets, beginning of year
21,695,143
4,414,360
1,777,390
27,886,893
Unrestricted
Revenue and public support:
Contributions:
Private individuals, corporations
and private foundations
Legacies and bequests
Public support
Special events (less direct costs
of $206,925)
In-kind rent income
Interest income
Net appreciation on investments
Net assets released from restrictions
$
Total revenue and public support
Change in value of annuities
and split interest agreements
Total expenses and losses
Net assets, end of year
$
18,589,299
$
$
5,428,789 $1,777,390
$
6,888,949
2,027,593
2,000
$
25,795,478
37
FINANCIALS
Total expenses
5,239,305
1,910,078
2,000
Total
CONSOLIDATED STATEMENT OF ACTIVITIES
Temporarily
Restricted
Unrestricted
Revenue and public support:
Contributions:
Private individuals, corporations
and private foundations
Legacies and bequests
Public support
Special events (less direct costs
of $200,458)
In-kind rent income
Interest income
Net appreciation on investments
Net assets released from restrictions
$
FINANCIALS
Total revenue and public support
$
4,682,467
2,178,945
-
Permanently
Restricted
Total
$
717,520
380,082
147,494
-
5,399,987
2,559,027
147,494
397,666
274,740
710,900
68,647
974,307
(59,038)
1,017,424 (1,017,424)
-
397,666
274,740
779,557
915,269
-
10,236,459
237,281
-
10,473,740
Expenses and losses:
Program services:
Research
Public education
Patient care services
3,107,199
2,086,782
4,698,506
-
-
3,107,199
2,086,782
4,698,506
Total program services
9,892,487
-
-
9,892,487
Supporting services:
Management and general expenses
Fund raising
723,135
1,543,635
-
-
723,135
1,543,635
Total support services
2,266,770
-
-
2,266,770
12,159,257
-
-
12,159,257
120,675
-
-
120,675
12,279,932
-
-
12,279,932
Change in net assets
(2,043,473)
237,281
-
(1,806,192)
Net assets, beginning of year
23,738,616
4,177,079
1,777,390
29,693,085
Total expenses
Change in value of annuities
and split interest agreements
Total expenses and losses
Net assets, end of year
$
21,695,143
$
4,414,360 $1,777,390
$
27,886,893
CONSOLIDATED STATEMENT OF FUNCTIONAL EXPENSES
FUNCTIONAL
EXPENSES
Public
Education
Patient Care
Services
Management
and General
Fund
Raising
Totals
128,625
390,582
458,304
304,790
472,581
1,754,882
Payroll taxes and benefits
30,348
96,074
84,884
82,913
156,537
450,756
Total salaries and benefits
158,973
486,656
543,188
387,703
629,118
2,205,638
4,079,342
287,500
4,139,880
-
-
8,506,722
Research symposium
6,277
101
-
945
7,323
Legal and accounting
-
-
-
86,193
287
86,480
Outside services
5,183
378,125
455,561
2,955
624,981
1,466,805
Printing and publications
2,280
397,379
35,189
3,582
31,925
470,355
-
124,299
24,025
-
-
148,324
880
118,659
39,072
6,230
230,680
395,521
Food, beverages and meetings
6,804
17,787
118,563
12,669
4
155,827
Telephone
2,855
16,743
13,546
14,748
11,429
59,321
-
794
-
45,926
8,309
55,029
1,558
2,687
21,263
13,239
31,306
70,053
17,360
29,557
41,411
12,150
23,147
123,625
-
-
-
69,938
-
69,938
Travel and transportaion
40,989
63,819
176,806
5,660
25,527
312,801
Lease and rentals
52,887
77,495
99,157
29,168
63,090
321,797
Bank and brokerage fees
-
-
-
1,139
51,545
52,684
Miscellaneous
-
1,200
2,116
-
6,775
10,091
4,216,415
1,516,145
5,166,589
22,242
33,032
44,112
$
Salaries
Grants
Public relations
Postage, freight and
courier services
Repairs and maintenance
Office supplies
General insurance
Interest paid to annuitants
Subtotal
Building and equipment
depreciation
TOTAL FUNCTIONAL
EXPENSES
$
4,397,630
$
2,035,833
$
5,753,889
-
303,597 1,109,950 12,312,696
14,834
38,828
153,048
$
706,134 $1,777,896 $14,671,382
39
FINANCIALS
Research
CONSOLIDATED STATEMENT OF FUNCTIONAL EXPENSES
FUNCTIONAL
EXPENSES
$
Salaries
$
123,487
410,346
Patient Care
Services
Management
and General
$
$
448,380
Fund
Raising
$
292,359
Totals
456,941
$
1,731,513
Payroll taxes and benefits
27,481
109,010
80,229
98,940
119,945
435,605
Total salaries and benefits
150,968
519,356
528,609
391,299
576,886
2,167,118
2,733,906
321,616
3,384,270
-
6,439,792
Research symposium
-
12,467
9,603
1,865
228
24,163
Legal and accounting
-
-
241
75,013
4,381
79,635
Outside services
9,211
362,244
264,992
231
461,894
1,098,572
Printing and publications
3,983
340,007
25,198
7,609
20,446
397,243
-
51,500
4,364
300
6,879
63,043
873
96,327
46,095
4,222
251,509
399,026
17,732
91,374
52,963
16,892
113
179,074
4,698
16,508
12,613
17,832
11,968
63,619
416
1,111
416
48,600
1,702
52,245
5,103
3,340
6,659
12,000
29,340
56,442
18,690
31,151
43,626
15,226
24,921
133,614
-
-
-
74,977
-
74,977
Travel and transportaion
85,900
121,038
189,520
8,540
23,456
428,454
Lease and rentals
52,930
81,237
84,508
30,059
66,729
315,463
Bank and brokerage fees
-
-
-
3,642
19,075
22,717
Miscellaneous
-
3,764
1,806
4,698
10,268
2,933,442
1,533,684
4,126,874
317,008
927,339
9,838,347
22,789
33,742
43,023
14,828
39,410
153,792
Grants
FINANCIALS
Public
Education
Research
Public relations
Postage, freight and
courier services
Food, beverages and meetings
Telephone
Repairs and maintenance
Office supplies
General insurance
Interest paid to annuitants
Subtotal
Building and equipment
depreciation
TOTAL FUNCTIONAL
EXPENSES
$
3,107,199
$
2,086,782
$
4,698,506
-
-
$
723,135 $1,543,635 $12,159,257
40
In 2008,
the fight
goes on.
INSIDE BACK COVER
artwork goes here
Are you with us?
1501 Northwest 9th Avenue/Bob Hope Road | Miami, FL 33136-1494
305.243.6666 | tollfree 800.327.4545 | fax 305.243.5595
email: [email protected] | visit us online: www.parkinson.org

AKR Broch 2006 - National Parkinson Foundation

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