Key Ingredients in the QV Range Moisturise all over

Moisturise all over
•P
atients with large areas of dry or sensitive skin will also benefit from bathing with
QV Bath Oil.
•Q
V Bath Oil contains light liquid paraffin, which has better skin adsorption than vegetable
oils or oatmeal baths.6
•T
he water dispersible formula ensures that the skin is uniformly hydrated and as a result helps
restore the skin’s natural suppleness and healthy glow.
• QV Bath Oil is an ideal cleanser for infants and the elderly.
Key Ingredients in the QV Range
•G
lycerin
- An effective humectant that is capable of attracting and holding water.
- It is an effective skin plasticiser.8
- It is non-toxic, non-allergic and non-irritating to the skin.
- Cases of sensitisation to glycerin (glycerol) are rare.
•L
ight liquid paraffin
- As an emollient, it promotes rehydration and suppleness of the skin.6,9
- It is adsorbed on the skin6 and provides an emollient film which reduces transepidermal water loss from the
stratum corneum to the environment.10
•S
oft white paraffin
- Also known as petroleum jelly, soft white paraffin is an occlusive agent with excellent emoliency.12
- It is non-toxic, non-irritating and non-carcinogenic.11,12
- The hydrocarbon mix in petroleum jelly interacts directly with the lamellar lipid layers to produce its effects.13
INNOVATION
It’s part of our DNA
eTHICS
From its inception as a family business in 1953, Ego has consistently delivered
effective, high-quality and innovative products. We are committed to creating the best possible skin
therapies for our customers. Ego’s heritage stems from a strong medical and ethical background.
We operate with honesty and integrity across all aspects of our business and value the relationships
we build with health professionals, customers and our staff.
eNVIRONMENT
Still proudly Australian-owned, Ego has led the way in the
development, manufacture and marketing of innovative skin care products. We take our responsibility
to the community and the environment seriously. Our aim is to improve people’s wellbeing; each year
we provide significant support to many charities and community organisations and invest in
dermatological education and research.
eVERYBODY
Ego has grown to become a world leader, producing a comprehensive
skin and health care range for Australia and the world. From our very first batch of Pinetarsol to our very
latest innovative skin care product, we always have your skin health in mind. That’s why millions of people
trust Ego to help care for their skin every day.
1. Campbell M.A., “Investigations into the pH of Various Soaps and Skin Products available in New Zealand,” Pharm Jour of NZ 1979.
2.White M.I., Jenkinson D.M., Lloyd D.H., “The effect of washing on the thickness of the stratum corneum in normal and atopic individuals,”
Br Jour of Derm, Vol 116, No. 4, April 1987, pp. 116, 525-530.
3. Cork M.J., “The importance of skin barrier function,” J Derma Treat 1997, 8:S7-13.
4. Fleischer A.B., Fleischer Jr. A.B., “The clinical management of itching: Therapeutic Protocols for Pruritis,” Informa Health Care, 2000, pp. 77.
5.Lucky A.W., Leach A.D., Laskarzewiski P., Wenck H., “Use of an Emollients as a Steroid – Sparing Agent in the Treatment of Mild to Moderate Atopic
Dermatitis in Children,” Paedi Derm, 1997, 4:321-324.
6.Taylor E.A., “Cutaneous Adsorption of Bath Oils,” Arch Dermat 1963, pp. 87:369.
7. Hunting ALL, Encyclopedia of shampoo ingredients. Micelle Press, England. 1983, pp. 238.
8. Fishor A.A., Contact Dermatitis, (3rd ed.) Lea & Febiger, Philadelphia. 1986, pp. 249.
9. Taylor, E.A., “Oil Adsorption,” J. Invest. Dermatol., 1961, pp. 37, 69-72.
10. Blank, I.H., “Emollients” in The Chemistry and Manufacture of Cosmetics, (2nd ed.) The Continental Press, Florida. 1975, Vol. 3, Chpt. 3, pp. 15-24.
11. Hunting ALL, Encyclopedia of shampoo ingredients. Micelle Press, England. 1983, pp. 317.
12. H
and book of Pharmaceuticals Excipients. A joint publication of the American Pharmaceutical Association and the Pharmaceutical Society of great
Britain, The Pharmaceutical Press, 1986, pp. 195.
13. Umbach W., “Cosmeceuticals – The future of cosmetics?” Cosmetics and Toiletries. 110(11):33-40, 1995.
14. Brewster B. Aquaporins: Stimulating AQP3, Cosmetics and Toiletries, 123:6. p20-26. June 2008
15. Brander J.M. Pores in the epidermis: aquaproins and tight junctions (Review). Int J Cosmet Sci. 29:413-422. 2007.
Always read the label and use only as directed.
EGO PHARMACEUTICALS PTY LTD, 21-31 Malcolm Road, Braeside, 3195, Australia
australia +61 3 9586 8800 toll free 1800 033 706 dubai +971 4258 8433
singapore +65 6562 7755 malaysia +60 3 7956 8868 new zealand toll free 0800 368 452
‘Ego’ and ‘QV’ are trademarks of Ego Pharmaceuticals Pty Ltd in Australia and other countries. ©2010 Ego.
[email protected]
www.egopharm.com
80955
www.qvskincare.com.au
Gently cleanse and
moisturise.
A LITTLE
Ego EVERY DAY.
QV emollient therapy for dry or sensitive skin conditions.
Remind your patients to avoid soap.
• Even ‘mild’ soap can be highly alkaline and can strip away the skin’s natural layer of protective oils.1
•S
oap also reduces the thickness and number of cell layers in the stratum corneum leaving the skin
dry and potentially susceptible to infection.2
Corneocytes
Corneocytes
Lipids
DRY SKIN
HEALTHY SKIN
Remind your patients to moisturise
frequently and all over.
Environmental
triggers
Factors impairing
epidermal barrier
•E
mollients have an indirect anti-inflammatory
action and may have a direct anti-proliferative
effect on the skin.3
•E
mollients help to decrease the severity
of atopic dermatitis and are important
in preventing recurrence.3
• Emollient
therapy also has a steroid
sparing effect.3,5
Emollients restore
epidermal barrier
IL-1
Scratch
Itch
Secondary
Cytokines
Eczematous
Lesions
Inflammatory
Mediators
Itch Scratch Cycle - adapted from Cork MJ.3
The QV range is ideal for patients with dry or sensitive skin.
•T
he QV range consists of products which are pH balanced. This helps prevent disruption of the skin’s acid mantle
thereby reducing the chance of irritation.
• QV contains gentle surfactants to provide effective cleansing without irritation.
• QV products contain high levels of emollients and gentle humectants.
• QV products have been dermatologically tested and found to be non-irritating to the skin.
•T
he QV range is free from colour, fragrance, propylene glycol, lanolin and its derivatives making it ideal
for sensitive skin types.
•Q
V products feel great on the skin which in turn can help to increase compliance and therefore efficacy of
emollient therapy.
•A
ll products in the QV range are non-comedogenic (won’t block pores), and suitable for daily use.
Glycerin transportation and skin hydration.
AQP3
Water
transport
Glycerin
transport
Glycerin content
Lipid synthesis
Cell
proliferation
Cell
migration
• SC hydration
• Skin elasticity
• Barrier recovery
Wound
healing
Proposed mechanism of AQP3 - adapted from Brewster B.14
Aquaporins (specifically aquaglyceroporins) are a family of proteins that form channels to facilitate water
transportation across cell membranes.15
AQP3 co-transports water and glycerin into and out of the epidermis15
– Glycerin is an humectant
– Where glycerin goes, water will follow
Glycerin transportation, both topically and systemically through stimulated AQP3 (Aquaporin)
channels has a direct impact on improved skin hydration, elasticity and barrier function recovery.14
• AQP3 are pH sensitive15
• At a pH of ~5, skin pH, AQP3 are inhibited
• If the pH of the stratum corneum increases AQP3 become permeable. For example, if you use soap
that has a high pH, the AQP3 will become permeable and water loss from the stratum corneum will
increase. Thus causing the skin to dry out.
•U
se of a pH balanced soap alternative such as QV will help to increase glycerin transportation whilst
not promoting water loss through the stratum corneum.
Stratum corneum, pH ~ 5
AQP3
Epidermis, pH ~ 7
Dermis
AQP3 - Glycerin transportation
There’s a QV product specially tailored to cleanse and moisturise
different levels of dry skin.
It’s important for patients to realise that a complete cleanse and moisturise routine is the best way to help with
sensitive skin. If they are using a soap alternative as a cleanser, then they should also make sure to moisturise
afterwards. There are many QV products designed to suit varying skin types and severity of conditions.
INGREDIENTS
MOISTURISING
CLEANSING
RATING
RATING
HHH
HHHH
INDICATIONS
CLEANSERS
QV WASH
Glycerin 10%
Lightly foaming cleanser
Moisturising
pH balanced
For normal or sensitive skin
QV BAR
HHH
HHHH
Lightly foaming cleansing bar
pH balanced
For normal or sensitive skin
QV GENTLE
Glycerin 15%
HHHH
HHHH
Medium foaming cleanser
Gentle blend of mild surfactants
WASH
Moisturising
pH balanced
For dry or sensitive skin
QV BATH OIL
Light Liquid Paraffin 85%
HHHH
HH
Water dispersible bath oil
Ideal for moisturising large areas
Non-greasy
Mild cleanser
Suitable for infants and the elderly
For dry or sensitive skin
QV INTENSIVE
Glycerin 60%
HHHHH
HHHH
Highly moisturising
Medium foaming cleanser
MOISTURISING
Gentle blend of mild surfactants
CLEANSER
Preservative free
pH balanced
For chronically dry skin
MOISTURISERS
QV SKIN
Soft White Paraffin 5%
HHH
Light moisturising lotion
Easy to apply
LOTION
All over body moisturiser
For normal or sensitive skin
QV CREAM
Glycerin 10%, Light Liquid Paraffin
10%, Soft White Paraffin 5%
HHHH
Highly concentrated moisturising cream
Ideal for areas that need extra hydration
For dry or sensitive skin
QV INTENSIVE
BODY
Light Liquid Paraffin 50.5%, Soft
White Paraffin 20%
HHHHH
Preservative free
Water free
MOISTURISER
QV LIP BALM
Highly emollient balm
For chronically dry skin
Light Liquid Paraffin 42.5%,
Soft White Paraffin 21%,
Ricinus Communis (castor)
seed oil 12.5%,
Methoxycinnamate 4%, Butyl
methoxydibenzoylmethane 2.5%
HHHHH
Soft soothing gel
Protects and moisturises
Unique applicator
Suitable for daily use
Cleansing and moisturising ratings have been developed based on the amount of moisturisers and cleansers in each product.
Ratings are relative to products within the same category.