Poster Programme

Poster Programme
P1
Effects of fermentation scales on biomass development and yeast cell viability
under beer fermentation conditions
X. Zhao, S. Procopio, T. Becker, TU München, Freising/D
P2
INOSIM process: simulation based scale-up of bioprocesses
K. Sulzbacher, INOSIM Consulting GmbH, Dortmund/D; G. Schembecker, TU
Dortmund/D
P3
Development of a new training simulator for bio-ethanol plants and its
application for ressource efficiency studies
V. Hass, Hochschule Furtwangen, Villingen-Schwenningen/D; S. Kuntzsch,
Hochschule Bremen/D; K.-M. Schoop, Ingenieurbüro Schoop GmbH,
Hamburg/D; M. Winterhalter, Universität Bremen/D; R. Pörtner, TU HamburgHarburg/D
P4
Multiple and directed integration of recombinant protein expression cassettes
into the genome of Pichia pastoris
J-P. Schwarzhans, D. Wibberg, J. Kalinowski, K. Friehs, Universität Bielefeld/D
P5
Oligosaccharide synthesis by use of ß-galactosidase in a variety of organic
solvents and a ionic liquid
R. Brakowski, K. Pontius, J. Hübner, M. Franzreb, Karlsruhe Institute of
Technology (KIT), Eggenstein-Leopoldshafen/D
P6
Enzymatic carboxylation of phenolics utilizing CO2 as starting material
L. Pesci, P. Gurikov, I. Smirnova, TU Hamburg-Harburg/D; K. Faber, University of
Graz/A; A. Liese, TU Hamburg-Harburg/D
P7
Specific power input in orbitally shaken bag bioreactors: an engineering
parameter for scale-up and scale-down
S. Werner, D. Eibl, Zurich University of Applied Sciences, Wädenswil/CH
P8
Parallel cultivation of microorganisms using bench scale and small scale rigidwall single-use bioreactors
S. Kleebank, DASGIP GmbH, Jülich/D; A. Niehus, Eppendorf AG, Jülich/D
P9
Characterization of an E.coli production process using a scale down model
K. Miehe, N. Zagler, D. Hädicke, S. Martens, T. Kaiser, B. Krampe, H. Tebbe,
Roche Diagnostics GmbH, Penzberg/D
P 10
Scale-down of a HGMS filter unit for lab scale implementation of separation and
reaction procedures in integrated processes
H. Al-Kaidy, R. Ulber, N. Tippkötter, TU Kaiserslautern/D
P 11
An automated magnetic platform for controlled enzymatic reactions of lab-in-adrop systems
H. Al-Kaidy, R. Ulber, N. Tippkötter, TU Kaiserslautern/D
P 12
Model-based strategy for cell culture seed train layout verified at lab scale
S. Kern, O. Platas, M. Schaletzky, R. Pörtner, TU Hamburg-Harburg/D; B. Frahm,
Hochschule Ostwestfalen-Lippe, Lemgo/D; V. Sandig, ProBioGen AG, Berlin/D
P 13
Metabolic engineering of Corynebacterium glutamicum for increasing lysine
production using a lysine riboswitch
L.B. Zhou, R.R. Bommareddy, A.P. Zeng, TU Hamburg-Harburg/D
P 14
Characterization of continuous nisin-production by Lactococcus lactis biofilms
on microstructured surfaces
M. Huster, C. Schlegel, R. Ulber, TU Kaiserslautern/D
P 15
Automated small-scale enzymatic membrane reactor: design, control and its
applications
A. Sitanggang, TU Berlin/D; A. Drews, Hochschule für Technik und Wirtschaft
Berlin/D; M. Kraume, TU Berlin/D
P 16
The cell cycle as a process parameter in mammalian cell culture
G. Fuge, TU Hamburg-Harburg/D; K. Riecken, Universitätsklinikum HamburgEppendorf/D; A. E. Castillo, U. Jandt, A. P. Zeng, TU Hamburg-Harburg/D
P 17
Production of the antibody fragment D1.3scFv in Bacillus sp.
A. Lakowitz, R. Biedendieck, R. Krull, TU Braunschweig/D
P 18
In situ purification of his-tagged products using functionalized super
paramagnetic iron oxide nanoparticles in Bacillus megaterium
J. Gädke, R. Biedendieck, R. Krull, TU Braunschweig/D
P 19
Production of high value food products by fermentation of biogenic waste
streams
N. Wolters, G. Schembecker, J. Merz, TU Dortmund/D
P 20
Production of recombinant proteins with E. coli from shake flask to industrial
scale
K. Friehs, R.S. Velur Selvamani, M. Telaar, E. Flaschel, Bielefeld University/D
P 21
Effective L-tryptophan production in Escherichia coli created by rational and
integrative molecular engineering
L. Chen, A.P. Zeng, TU Hamburg-Harburg/D
P 22
Production of fusicoccadiene by Saccharomyces cerevisiae
L. Halka, M. Freder, R. Wichmann, TU Dortmund/D
P 23
Gas-fermentation with Acetobacterium woodii in a membrane reactor
C. Kantzow, A. Mayer, D. Weuster-Botz, TU München, Garching b. München/D
P 24
Scale-up / scale-down studies of fermentation processes with Komagataella
pastoris
A. Schmideder, TU München, Garching b. München/D; A. Stratmann, W42
Industrial Biotechnology GmbH, Marl/D; D. Weuster-Botz, TU München,
Garching b. München/D
P 25
Tunable aqueous polymer-phase impregnated resins-technology - a technology
for downstream processing of biomolecules
I. Kaplanow, G. Schembecker, J. Merz, TU Dortmund/D
P 26
3D-printed individual labware in biosciences by rapid prototyping
T. Lücking, F. Sambale, D. Bulnes-Abundis, C. Busse, S. Beutel, T. Scheper,
Universität Hannover/D
P 27
Inertial based fast media exchange in a microfluidic spiral cell separator for
metabolomic analysis of microorganisms
E. Hans, S. Bohne, A.-P. Zeng, TU Hamburg-Harburg/D
P 28
iHCDC - improved high cell-density cultivation process for E. coli
E. Sanders, B. Beckmann, S. Kaul, P. Derr, Hochschule für Angewandte
Wissenschaften Hamburg/D
P 29
New perspectives in shake flask monitoring using a multisensory platform for
scale up process improvement
C. Ude, Universität Hannover/D; M. Findeis, G.T. John, PreSens Precision
Sensing GmbH, Regensburg/D; T. Scheper, S. Beutel, Universität Hannover/D
P 30
New high capacity chromatography resins for antibody purification
M. Frhr. v. Roman, S. Berensmeier, TU München, Garching b. München/D
P 31
Bench-top lab automation systems for a faster scale up of bioprocesses - current
solutions and future prospects
F. Lenk, M. Vogel, C. Otto, P. Labudde, P. Oberthür, T. Bley, E. Boschke, TU
Dresden/D
P 32
100 years of fed-batch technology - scaling experiences and implications for
further developments
P. Neubauer, S. Junne, TU Berlin/D
P 33
Quasi-continuous bioprocessing with Pichia pastoris - scale-up productivity in a
scale-down production plant
S.-O. Borchert, F. Aupert, M. Huettemann, S. Weyand, C. Kober, R. Luttmann, TU
Hamburg-Harburg/D
P 34
Systems biology approach for determining the physiology of an oleaginous yeast
R.R. Bommareddy, W. Sabra, A.P. Zeng, TU Hamburg-Harburg/D
P 35
Multiscale cytokine purification using membrane chromatography
G. Brockmeier, I. Pepelanova, S. Beutel, U. Rinas, Universität Hannover/D; L.
Villain, Sartorius Stedim Biotech GmbH, Göttingen/D; T. Scheper, Universität
Hannover/D
P 36
Scale down of bioprocesses - the "pipe based bioreactors" concept
G. Gastrock, Institut für Bioprozess- und Analysenmesstechnik e.V., Heilbad
Heiligenstadt/D
P 37
Enzymatic production of acetylated cello-oligomers from water-soluble cellulose
acetate
S. Kluge, A.C. Spiess, RWTH Aachen/D
P 38
Scale-up of fermentative lactic acid production from renewable feedstocks
D. Pleissner, Leibniz-Institute for Agricultural Engineering, Potsdam/D; J. Venus,
Leibniz-Institute of Agricultural Engineering, Potsdam/D
P 39
Scalability of marine cultivations of the heterotrophic algae Crypthecodinium
cohnii in single-use bioreactors
A. Marbà-Ardébol, F. Hillig, O. Zakrzewski, TU Berlin/D; J. Emmerich, SOPAT
GmbH, Berlin/D; P. Neubauer, S. Junne, TU Berlin/D
P 40
The importance of local mass transfer phenomena in scale-up processes
S. Heithoff, N. Räbiger, Universität Bremen/D
P 41
Seamless scale-up of an antibody upstream process from early process
development to 2500L pilot scale supported by PAT
J. Dietrich, Bayer Healthcare Pharma, Wuppertal/D; C. Knappe, Bayer
Technology Services GmbH, Leverkusen/D; T. Thuete, Bayer Healthcare Pharma,
Wuppertal/D; J. Traenkle, Bayer Technology Services GmbH, Leverkusen/D; A.
Jockwer, Bayer Healthcare Pharma, Wuppertal/D
P 42
Decision tree for selection of suitable cultivation parameters for mammalian
cell culture processes
R. Pörtner, S. Kern, TU Hamburg-Harburg, Hamburg/D; D. Eibl, Zürcher
Hochschule für Angewandte Wissenschaften, Wädenswil/CH
P 43
Novel two compartment setup enables faster scale-up study: a tribute to the
robustness of C. glutamicum
M. Limberg, T. Aryani, W. Wiechert, M. Oldiges, Forschungszentrum Jülich
GmbH/D
P 44
Scale-down approach: tools for the understanding of cellulase production for
2G-bioethanol
N. Hardy, IFP Energies nouvelles, Rueil-Malmaison/F; C. Béal, UMR 782
AgroParisTech INRA, Thiverval-Grignon/F; F. Augier, H. Gonzalez Penas, M.
Moreaud, IFP Energies nouvelles, Solaize/F; F. Ben Chaabane, IFP Energies
nouvelles, Rueil-Malmaison/F; A. W. Nienow, University of Birmingham/UK
P 45
Bioprocess automation for fast microbial strain selection and detailed
quantitative phenotyping
A. Radek, S. Unthan, M. Oldiges, S. Noack, Forschungszentrum Jülich GmbH/D
P 46
5-Hydroxytryptophan and serotonin production by synthetic pathways of
engineered Escherichia coli strains
J.A. Mora-Villalobos, TU Hamburg-Harburg/D
P 47
On-line monitoring and control of a production process with Pichia pastoris
based on spectroscopic measurements and MVDA
J.-P. Voss, N.E. Mittelheuser, R. Lemke, J. Hirsch, R. Luttmann, Hochschule für
Angewandte Wissenschaften Hamburg/D
P 48
Simulating large scale conditions in a scale-down bioreactor: impacts on cell
physiology of recombinant Escherichia coli
C. Reitz, L. Ping, S. Junne, P. Neubauer, TU Berlin/D
P 49
Scale up and scale down of truly continuous bioprocesses
K. Bühler, R. Karande, B. Halan, A. Schmid, Helmholtz Zentrum für
Umweltforschung UFZ, Leipzig/D
P 50
In silico scale-down/scale-up of column liquid chromatography using a
generalized porous media equation
T. Hahn, T.C. Huuk, Karlsruhe Institute of Technology (KIT), Karlsruhe/D; V.
Heuveline, Universität Heidelberg/D; J. Hubbuch, Karlsruhe Institute of
Technology (KIT), Karlsruhe/D
P 51
Implementation of an alternative concept for process integration in USP and
DSP of antibody manufacturing
P. Gronemeyer, R. Ditz, J. Strube, TU Clausthal/D
P 52
Internal illumination of a 15 L - airlift photobioreactor via wireless light
emitters
M. Heining, A. Sutor, R. Buchholz, Universität Erlangen-Nürnberg/D
P 53
In situ reactive extraction of itaconic acid from Aspergillus terreus fermentation
broth
D. Kreyenschulte, R. Kossack, L. Regestein, J. Büchs, RWTH Aachen/D
P 54
Scalability of mechanistic models for ion exchange chromatography
T. Huuk, T. Hahn, Karlsruhe Institute of Technology (KIT)/D; J. Griesbach, S.
Hepbildikler, Roche Diagnostics GmbH, Penzberg/D; J. Hubbuch, Karlsruhe
Institute of Technology (KIT)/D
P 55
Basidiomycetous enzymes for flavour transformation reactions
B. Fuchs, V. Esparan, U. Krings, R.G. Berger, Universität Hannover/D
P 56
A multi-fixed-bed fermenter system as a powerful tool for bioprocess
development applied for immobilized lactic acid bacteria
R. Faschian, S. De, TU Hamburg-Harburg/D; C. Zenneck, medorex e.K., NörtenHardenberg/D; R. Pörtner, TU Hamburg-Harburg/D
P 57
Bioactive metabolites from Myxobacetria - process characterization and
development towards increased productivity
A. Beckmann, S. Bernecker, K. Bohle, M. Stadler, Helmholtz Centre for Infection
Research, Braunschweig/D
P 58
Perspectives for the production of ethyl acetate by yeasts based on renewable
raw material
C. Löser, TU Dresden/D; T. Urit, Nakhon Sawan Rajabhat University/T; T. Bley,
TU Dresden/D
P 59
Model-based scale-up in membrane chromatography
P. Ghosh, E. Velali, E. von Lieres, Forschungszentrum Jüllich GmbH/D
P 60
Die Zentrifugalverteilungschromatographie als Reaktor zur enzymatischen
Hydrolyse in wässrig/organischen Zweiphasensystemen
J. Krause, G. Schembecker, J. Merz, TU Dortmund/D
P 61
Miniaturization of purification strategies for systematic downstream process
development
F. Thygs, J. Merz, G. Schembecker, TU Dortmund/D
P 63
Production of the tryptophan based antibiotic rebeccamycin
J. Blotenberg, R. Krull, TU Braunschweig/D
P 64
Considerations for cell passaging in cell culture seed trains
T. Hernández Rodríguez, Ostwestfalen-Lippe University of Applied Sciences,
Lemgo/D; R. Pörtner, TU Hamburg-Harburg/D; B. Frahm, Ostwestfalen-Lippe
University of Applied Sciences, Lemgo/D
P 65
Making predictions for systems metabolic engineering of E. coli using a "real
cell" model
L. Song, A.P. Zeng, TU Hamburg-Harburg/D
P 66
Optimization of AMDase catalyzed profene synthesis
M. Aßmann, TU Hamburg-Harburg/D; S. Gaßmeyer, R. Kourist, Ruhr-Universität
Bochum/D; A. Liese, TU Hamburg-Harburg/D
P 67
Fast transcriptional responses of Corynebacterium glutamicum facing CO2
gradients
M. Graf, Universität Stuttgart/D; J. Buchholz, Universität Stuttgart/D and Sandoz
GmbH, Kundl/A; A. Freund, T. Busche, J. Kalinowski, Center for Biotechnology
(CeBiTec), Bielefeld/D; B. Blombach, R. Takors, Universität Stuttgart/D
P 68
Rational design of riboswitch with expanded response range of small molecules
for metabolic flux control
C. Ma, L. Zhou, A.-P. Zeng, TU Hamburg-Harburg/D
P 69
Manipulation of multi-enzyme complex: computational and experimental
analyses of structure and function
U. Jandt, S. Hezaveh, J. Guo, A.P. Zeng, TU Hamburg-Harburg/D
P 70
Transcription profiling of scale-up dependent regulatory phenomena
J. Simen, M. Löffler, A. Freund, Universität Stuttgart/D; G. Jäger, Universität
Tübingen/D; R. Takors, Universität Stuttgart/D
P 71
Modelling of local behavior of the gas phase in stirred tank bioreactors with
CFD: an Euler-Lagrange approach for scale-up predictions
J. Wutz, A. Lapin, Universität Stuttgart/D; M. Berger, Boehringer Ingelheim
Pharma GmbH & Co. KG, Biberach an der Riss/D; R. Takors, Universität
Stuttgart/D
P 72
Electricity driven synthesis in bioreactors: upgrading conventional
infrastructure
C. Stang, L. Rosa, S. Hunger, C. Gimkiewicz, T.R. dos Santos, A. Zehnsdorf, F.
Harnisch, Helmholtz Centre for Environmental Research, Leipzig/D
P 73
Improved method for the screening and sizing of depth and sterile filters in-line
M. Hannappel, Merck Chemicals GmbH - Merck Millipore, Schwalbach/D
P 74
Modeling mass transfer in small scale reactors using Computational Fluid
Dynamics
H. Larsson, K. V. Gernaey, U. Krühne, Technical University of Denmark/DK
P 75
The trail to the industrial scale
S. Briechle, M. –H. Kopf, S. Freyer, BASF SE, Ludwigshafen/D
P 76
Scale up of a Salvia suspension culture from shake flask to bioreactor systems
of several litres
C. Haas, HTW Dresden/D and TU Dresden/D; Mario Opitz, HTW Dresden/D;
Thomas Bley, TU Dresden/D; Jörg-Uwe Ackermann, HTW Dresden/D
P 77
Transient physiologic states: friend or foe?
W.N. Reichelt, M. Brillmann, P. Thurrold, C. Herwig, Vienna University of
Technology/A
P 78
Natural elicitors enhancing triterpene production
S. Kümmritz, M. Louis, S. Gantz, H. Delenk, TU Dresden/D; C. Haas, TU
Dresden/D and Hochschule für Technik und Wirtschaft Dresden/D; T. Bley, J.
Steingoewer, TU Dresden/D
P 79
BioSpeckle: development of a non-invasive sensor for determination of biomass
in biotechnological processes by Laser-Speckle-Photometry
C. Schott, T. Bley, J. Steingroewer, TU Dresden/D; B. Bendjus, U. Cikalova,
Fraunhofer IKTS/D; T. Werner, Werner industrial electronics, Kreischa/D
P 80
Determination of the volumetric mass transfer coefficient (kLa) using the
dynamic Na2 SO3 -method: Analysis with offgas-sensors
D.Bittner, Westfälische Hochschule Recklinghausen/D; H. Müller, Blue Sens gas
sensor GmbH, Herten/D; F. Eiden, Westfälische Hochschule Recklinghausen/D