Transition Research Faculty

Transcription

Transition Research Faculty
meet the faculty
Research Faculty
continued from page 4
NeurOSurGerY At MOuNt SINAI
A Newsletter Published for Colleagues and Friends of the Department of Neurosurgery
Fall 2008
Fatima Sehba, PhD
Marat Avshalumov, PhD
Yuangen Chen, PhD
Luni Emdad, MBBS, PhD
Associate Professor
Assistant Professor
Assistant Professor
Assistant Professor
Chairman’s message continued from page 1
develop original NIH-funded research laboratories and evolve the different neurosurgical subspecialties. We are fortunate that Dr. Post
remains an active member of the department, continuing his clinical, academic and educational activities at full pitch.
It is on the shoulders of these giants in neurosurgery that I take over as chair, with hopes to bring the department to even greater
achievements in the years to come. As you will see from the pages that follow, the department is richly endowed with talented surgeons,
physicians, and researchers all dedicated to advancing the field of neurosurgery. Our residency, the subject of our next newsletter, has
never been stronger, and our alumni are achieving great things. Over the coming months this newsletter will feature many of the
remarkable individuals that make up the neurosurgical community at Mount Sinai. As always, we invite our friends, guests, alumni,
and collaborators to participate in our numerous educational offerings, which can be found near the end of each newsletter.
Joshua B. Bederson, MD
Professor and Chairman
Neurosurgery at Mount Sinai
Department of Neurosurgery
One Gustave L. Levy Place
Box 1136
New York, NY 10029-6574
Neurosurgery at Mount Sinai
is published for colleagues
and friends of the Department
of Neurosurgery at The Mount Sinai
Medical Center.
Please contact Debbie Winn
[email protected]
for submissions, suggestions
or questions. Visit our website,
www.mssm.edu/neurosurgery
index.html.
Message from the Chairman
It is a great honor to take over
the reigns of chairman of the
Department of Neurosurgery
at Mount Sinai, which has a
long and illustrious history
stemming from Mount Sinai’s founding in
1852. Our neurosurgery service was established in 1914 under Charles elsberg,
cofounder of the Society of Neurological
Surgeons. He was succeeded by Dr. Harold
Neuhof and in 1932 by Dr. Ira Cohen who
formed the Department of Neurosurgery,
established the residency training Program
in 1947 and remained its head to 1950. Dr.
Leo M. Davidoff became chair in 1951. A
prolific writer, he was also President of the
Society of Neurosurgical Surgeons and was
succeeded by Dr. Sidney Gross who was
chair from 1956 to 1970. under Dr. Gross’
leadership the AMA and ABMS approved
our neurosurgery residency in 1956. Dr.
Leonard Malis was chair of the department
from 1970 to 1991. Among many firsts
attributed to Dr. Malis was the first microneurosurgical operation in 1965, Mount
Sinai’s first practical course in 1968, and
numerous technological advances including
creation of the first automatic angiographic
cassette changer, full-column myelography,
the first description of Bragg peak radiation
effects in neural tissue and development of
the dedicated bipolar spark-gap. the “Malis”
bipolar is widely cited as the most common
neurosurgical instrument in use throughout
the world today. under our immediate past
chair, Dr. Kalmon Post, the department more
than doubled in size. During Dr. Post’s 17
year tenure from 1991 to 2008 the department
benefited from his world class clinical practice, his numerous contributions to the
neurosurgical literature and his ability to
foster young academic neurosurgeons to
continued on page 12
Transition
Joshua B. Bederson, MD, named
Chair of Neurosurgery
Joshua Bederson, MD, Professor of
Neurosurgery and Director of the
Cerebrovascular Surgery Program, was
named Chair of the Department of
Neurosurgery, effective July 1, 2008.
Dr. Bederson has served as Vice Chairman
of the Department since 2001 and Director
of the Neurosurgery residency Program
since 2002. He succeeds Kalmon D. Post,
MD, who over the past 17 years, led the
department to a position of national
prominence.
“It is an honor for any neurosurgeon to be
named chair of any major academic neurosurgery training program in this country,”
says Dr. Bederson. “to achieve this goal at
Mount Sinai, one of the country’s great
institutions, and the same institution
where I was born, is an honor that carries
much responsibility.”
continued on page 2
Kalmon D. Post, MD, becomes
Chairman Emeritus
Dr. Post succeeded Dr. Leonard Malis as
Chairman of Mount Sinai’s Neurosurgery
Department in 1991. Having trained under
Dr. Joseph ransohoff at New York
university, Dr. Post came to Mount Sinai
from Columbia, where he had been Vice
Chairman of the Department of
Neurological Surgery.
During his tenure, Dr. Post significantly
expanded the department, in personnel,
areas of clinical, academic and research
expertise, resources and physical space.
under his leadership, the faculty grew to 12
full-time and 13 voluntary neurosurgeons,
four basic scientists, and seven more faculty
with joint appointments in Neurology,
radiology, endocrinology and Anesthesia.
Dr. Post added specialists in Functional,
Skull Base, endovascular and Spine. this
more specialized faculty pioneered
advances in frameless stereotactic cranial
surgery, computer-assisted image-guided
continued on page 2
Dr. Bederson named chair
continued from page 1
Dr. Post steps down
continued from page 1
Dr. Bederson’s career at Mount Sinai began in 1992 as the Director
of the Cerebrovascular Surgery Program. He established the first
basic science lab in the Department of Neurosurgery, developing
models of stroke and subarachnoid hemorrhage. His laboratory
has been continuously funded by the National Institutes of Health
(NIH) since 1997.
minimally invasive surgery, endoscopic neurosurgery, microsurgery, physiologic monitoring in the operating room, spinal
disease, management of neurovascular abnormalities and tumors
of the nervous system, and the surgery of epilepsy. the number of
operations performed in microvascular neurosurgery, pituitary
and acoustic surgery, epilepsy and movement disorder surgery,
and spine surgery dramatically increased. He recruited two
neurointensivists, neurologists with a joint appointment in
Neurosurgery, to work with the neurosurgeons in the ICu. In
terms of its physical resources, the department remodeled the
eighth floor of Annenberg to accommodate 19 academic offices,
four operating rooms, an additional waiting room, and a neurosurgical ICu that was expanded from 12 to 16 beds. Dr. Post
created a Clinical Center for Skull Base Surgery at Mount Sinai in
conjunction with the Department of Otolaryngology and recruited
a scientist who organized the department’s intraoperative neurophysiological monitoring team. He also facilitated the purchase
of the Novalis system, at the time one of the most sophisticated
approaches to stereotactic radiosurgery and radiotherapy. In
2002, Dr. Joshua Bederson was appointed Vice Chairman and
residency Program Director, and in 2003, Dr. H. richard Winn
joined the faculty as Director of research. the number of NIH
grants increased to two rO1s and one rO3.
In 2002, Dr. Bederson was the first neurosurgeon at Mount Sinai
to receive an NIH rO1 as a principal investigator. He developed
one of the first interdisciplinary clinical programs with the
Department of Neurology Stroke Program, and continues his
collaborative efforts with the Departments of Otolaryngology, the
Cancer Institute, and the translational Neuroscience Center. Dr.
Bederson has served as Chair of the American Association of
Neurological Surgeons/ Congress of Neurological Surgeons
Cerebrovascular Section. He is Chair of the American Heart
Association’s writing group on Subarachnoid Hemorrhage and
serves on numerous neurosurgical societies.
“Neurosurgery is a vibrant field that attracts talented individuals
committed to understanding the complexities of surgical problems
of the nervous system,” Dr. Bederson says. “By collaborating with
the many accomplished physicians and scientists at Mount Sinai, I
hope we will continue to advance the field and develop treatments
for the challenging problems our patients face.”
under Dr. Post’s Chairmanship, the department created the
Leonard. I. Malis, MD/Corinne and Joseph Graber endowed
Chair in Neurosurgery, as well as four annual lectureships: the
Sidney A. Hollin, MD, endowed Lecture; the Jeannette and
Bernard S. Post, MD, endowed Lecture; the Ved P. Sachdev,
MD, endowed Lecture; and the Leonard I. Malis, MD, endowed
Lecture. the Kalmon D. Post resident research Prize, which
acknowledges and promotes excellence in scholarship, was
established to be awarded annually for the best peer-reviewed
manuscript by a resident that has been published or accepted for
publication during the preceding year.
Dr. Bederson earned his medical degree and completed a residency
in neurosurgery at the university of California, San Francisco.
During residency he completed advanced study programs in
neuropathology at the university of torino in Italy, as well as
microvascular and skull base neurosurgery at the university
Hospitals of Zurich, Switzerland, and the university Medical
Center in Ljubljana, Slovenia. He completed a fellowship in
cerebrovascular surgery at the Barrow Neurological Institute.
Dr. Bederson specializes in the treatment of complex intracranial
and spinal pathology such as meningiomas, schwannomas, craniopharyngiomas, pituitary tumors, giant intracranial aneurysms,
acoustic neuromas, neurovascular compression syndromes like
trigeminal neuralgia, Chiari malformations, as well as treatment
of cervical and lumbar spine disease. His vascular practice
includes the treatment of aneurysms, arteriovenous malformations,
cavernous malformations, cartoid artery disease, moyamoya
disease and extracranial-intracranial bypass procedures. Dr.
Bederson has performed more than 2500 neurosurgical operations
at Mount Sinai.
Dr. Post trained 38 residents, including more women neurosurgeons than have been trained in any other department in the
country. He built one of the country’s largest neurosurgical
practices, specializing in acoustics with hearing preservation,
pituitary and other skull base tumors. In addition to his busy
surgical schedule, he chaired or served on many boards and committees at Mount Sinai, including the leadership of searches for
the chairs of Otolaryngolgy and Surgery, the chairmanship of the
executive Board, and, for four years, the presidency of the Faculty
Practice Association. Dr. Post inherited a strong department with
robust potential, continued the tradition of excellence and vision,
and leaves an extraordinary legacy at the Mount Sinai Hospital.
Rising in the Rankings
U.S. News analyzed data on 5,453 medical centers to produce this year’s specialty rankings. Mount Sinai’s Neurology and Neurosurgery ranked 16,
up from 21 in 2007. “This is a remarkable achievement,” says Dean Kenneth Davis, MD. These specialties are fiercely competitive.”
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Meet the Faculty
Full Time Neurosurgery Faculty
Joshua B. Bederson, MD
Kalmon D. Post, MD
Isabelle M. Germano, MD
H. Richard Winn, MD
Professor and Chairman
Professor and Chairman Emeritus
Professor
Professor
Cerebrovascular and Skull Base Surgery
Pituitary Tumors, Acoustic Neuroma
Radiosurgery, Stereotactic Neurosurgery
Cerebrovascular, Tumors
212-241-2377
212-241-0933
212-241-9638
212-241-9128
Ron L. Alterman, MD
Aman Patel, MD
Chun S. Chen, MD
Tanvir Choudhri, MD
Associate Professor
Associate Professor
Assistant Professor
Assistant Professor
Functional Neurosurgery
Endovascular Treatment of
Cerebrovascular Disorders
Skull Base Tumors
Complex Spine Disorders
212-241-0050
212-241-3457
212-241-8480
212-241-8560
Arthur L. Jenkins III, MD
Nirit Weiss, MD
Errol Gordon, MD
Jennifer Frontera, MD
Assistant Professor
Assistant Professor
Assistant Professor, Neurologist
Assistant Professor, Neurologist
Complex Spine Disorders
Complex Spine, General Neurosurgery
Neurointensivist
Neurointensivist
212-241-8175
212-241-6820
212-241-2114
212-241-9512
continued on page 4
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New Faculty
meet the faculty continued
Jamie Ullman, MD, ELMHURST FACULTY
Hang Byun, MD, ELMHURST FACULTY
Associate Professor
Associate Professor
Assistant Professor
Cerebrovascular therapy, spine interventions
Intraoperative Monitoring
Neurotrauma, Neurosurgical Critical Care
General Neurosurgery, Neurotrauma
212-241-3457
212-241-9543
718-334-2772
718-334-2772
Don Weisz, PhD
David M. Johnson, MD
Assistant Professor
Neurointerventional Radiology:
Voluntary Clinical Faculty
Marc S. Arginteanu, MD
Martin Camins, MD
Frank M. Moore, MD
Alfred A. Steinberger, MD
Associate Clinical Professor
Clinical Professor
Associate Clinical Professor
Assistant Clinical Professor
Complex Spine and General Neurosurgery
Complex Spine and General Neurosurgery
Complex Spine and General Neurosurgery
Complex Spine and General Neurosurgery
212-570-0100
212-410-6990
212-410-6990
212-410-6990
Faculty with Secondary Appointments
Robert Aiken, MD
Eliza B. Geer, MD
Eu-Meng Law, MD
Thomas Naidich, MD
Irene P. Osborn, MD
Associate Professor
Assistant Professor
Associate Professor
Professor
Associate Professor
Neuro-Oncology, Brain Tumors
Endocrinology, Pituitary Diseases
Neuroradiology
Neuroradiology
Anesthesiology
212-241-4503
212-241-7975
212-241-4261
212-241-3423
212-241-7467
Resident Graduation
Dr. errol Gordon, MD, came to Mount Sinai
in July 2008 as an assistant professor with a joint
appointment in Neurology and Neurosurgery
after spending two years at Columbia university
Medical Center as a Post Doctoral Fellow and
Clinical Instructor in Neurocritical Care. After
earning a BS at Sophie Davis City College, Dr.
Gordon attended SuNY Downstate Medical
College and did his residency at the Medical College of Wisconsin.
He will be working in the Neurosurgical ICu.
Drs. Joshua Bederson, Harlan Bruner, Alex Post and Kalmon Post
Luni emdad, MBBS, PhD, joined the Department
of Neurosurgery in June 2008 as an Assistant
Professor on the research track, coming from
Virginia Commonwealth university in
richmond, Virginia, where she was an Assistant
Professor in the Department of Human Genetics.
Prior to that, she served as a Postdoctoral
research Scientist (12/2002-5/2006) and an
Associate research Scientist (5/2006-12/2007) in the Department
of Pathology and urology at Columbia university, College of
Physicians and Surgeons. She will be working in the laboratory of
Isabelle Germano, MD, investigating the effects of mouse and
human embryonic stem cells-derived astrocytes conditionally
expressing pro-apoptotic genes on human malignant glioma.
the annual neurosurgery farewell to the chief resident dinner
was held at tavern on the Green on June 19. Parents and family
members of Harlan Bruner and Alex Post joined other residents,
faculty, nurses and staff of the department and were touched to
hear the heartfelt tributes to both chiefs whose year of leadership
was especially successful. Harlan and his wife Kathleen Converse
are heading to Milwaukee, Wisconsin, where Harlan will be doing
a spine fellowship at Froedtert Memorial Lutheran Hospital of the
Medical College of Wisconsin. Alex Post, Lauren and son Hayden
(who visited the offices in the department regularly and will be
missed!) will be in Chicago where Alex is doing a fellowship in
Pediatric Neurosurgery at Children’s Memorial Hospital, and
Lauren will continue her work as an emergency room physician.
We wish them all the very best in their new adventures.
New Residents
Sharona Ben-Haim, MD
MD: University of California, San Diego
BA: University of California, Berkeley, Molecular Biology
While in medical school, Sharona was honored by the San Diego Medical Society with the robert e. Hertzka Student
Leadership Award. Some of her leadership positions included Medical Student Board representative for the San Diego
Medical Society Foundation, Medical Student Director of the San Diego County Medical Society, Vice President of the
American Medical Student Association at uCSD and Student Coordinator of the student–run free clinic at uCSD. She
also was editor-in-Chief of The Human Condition, uSCD’s Art and Literary Magazine, as well as a food critic for the San
Diego Community Newspaper Group. During a one-year research fellowship at Harvard Medical School under emad eskandar, MD,
Director of Functional and Stereotactic Neurosurgery at MGH, Sharona studied the role of the globus pallidus in the inhibition of motor
programs using microelectrode recordings in a primate model.
Madhu Jannapureddy, MD
MD: Baylor College of Medicine
BS: Johns Hopkins University, Biomedical Engineering
In addition to his outstanding academic record, Madhu exhibited his leadership skills while in medical school: he was
a health careers mentor in the National Youth Leadership Forum, a peer resource network mentor, as well as a Baylor
College of Medicine representative to the texas Political Action Committee and a charter officer of the school’s
Professionalism Committee. He served on the Medical ethics Curriculum review Committee and the Compassion in
the Art of Medicine Curriculum Advisory Committee, and found time to volunteer for Habitat for Humanity. His
biomedical engineering background is helpful in his hobby of building computer hardware and learning about new technologies. the
Department is looking forward to his contributions to our baseball team next year!
Research Faculty continued on page 12
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5
News Briefs
Dr. Isabelle Germano was awarded an rO1 from the NIH/NCI.
the $1,700,000 five year grant is for Transgenic in vivo delivery of
mda-7/Il-24 for malignant glioma therapy. At the AANS meeting in
Chicago in April, Dr. Germano participated on the faculty of a
practical course on brain mapping and epilepsy. On September 13
she spoke at a Medical education Oncology Seminar on “treatment
of neurological malignancy including surgical treatment.”
A Grand Tribute to Kalmon D. Post, MD
on aneurysms and next on stroke and carotid stenosis. In April, he
was a visiting professor at the Department of Neurological Surgery
at the university of California in Los Angeles. the following
month, he spoke to basic scientists at Shinshu university School
of Medicine in Matsumoto City, Japan, and was also a Special
Lecturer in the Department of Neurosurgery there. Dr. Winn was
the Mayfield Lecturer and Graduation Speaker for the Department
of Neurosurgery at the university of Cincinnati in May and the
Grand rounds Lecturer and Graduation Speaker at Penn State
university Medical School in Hershey, Pennsylvania, in June.
As Chair of the AANS/CNS Cerebrovascular Section, Dr. Joshua B.
Bederson gave a “State of the Section” presidential address at the
AANS meeting in April in Chicago. He also oversaw the annual
Cerebrovascular Section meeting in New Orleans in February.
Associate Professor Fatima A. Sehba, PhD, lectured on
Mechanisms of cerebral injury after subarachnoid hemorrhage to the
Loma Linda university Neuroscience research Consortium on
April 4, 2008. Dr. Sehba leads research of early brain injury after
subarachnoid hemorrhage.
Dr. Arthur Jenkins III, participated as a faculty member in a course
titled, the Aging Spine, held May 8 and 9 in New York City. Dr.
Jenkins lectured on Influence of bone cement to the blood supply of
vertebrae and the adjacent discs in the course section, the uses of
Cement in the Aging Spine. Dr. Jenkins has been awarded a two
year grant as co-investigator for promoting recovery of spinal cord
function after injury by treating with microbeam radiation therapy.
the Department fielded a
team to participate in the Fifth
Annual Neurosurgery
Charity Softball tournament
sponsored by George M.
Steinbrenner III and the New
York Yankees on Saturday,
June 7 in Central Park. Mayor
Michael Bloomberg threw out
the honorary first pitch, as this
date has been declared “Neurosurgery Charity Softball
tournament Day” in the City of New York. Competition was
very stiff this year with 16 teams competing, and Sinai did not
repeat its high finish of the past two years. everyone had a good
time, however, and will practice harder for next year’s event!
Dr. Jamie ullman was elected to the executive Committee of the
Congress of Neurological Surgeons as Member-At-Large to
serve a three-year term. She is an Associate editor for the
Congress Quarterly.
Marat Avshalumov, PhD, received a two year grant from the
NIH/NINDS. His study is focused on the effect of unbalanced
formation of reactive oxygen species on physiological properties
of dopaminergic neurons in substantia nigra.
ronit Gilad, MD, PGY 6, won the $2,000
Kalmon D. Post Neurosurgery Resident
Research Award for the paper, Uncorrected
sagittal plane imbalance predisposes to
symptomatic instrumentation failure, published in the December 12, 2007, Spine
Journal. Authors are ronit Gilad, Chirag
Gandhi, Marc Arginteanu, Frank Moore,
AA Steinberger and Martin Camins.
Dr. and Mrs. Kalmon Post
hosted three residents, erin Biro,
Harshpal Singh and Alex Post,
who attended Neurosurgery in
the rockies in February. each
resident gave a talk and also
had time to enjoy the wonderful
snow conditions.
Congratulations to PGY2 Jake Gologorsky, MD,
who was nominated by the Mount Sinai School of
Medicine Class of 2009 for a special award from the
Arnold P. Gold Foundation. Presented on June 30
at the Student Clinician Ceremony, Jake’s certificate
reads: “the Gold Foundation Humanism and excellence in
teaching Award to an Outstanding resident role Model.”
NSICu news: Jennifer Frontera, MD, and the NSICu have received
IrB approval for the IHOP study (Intracranial Hemorrhage
Outcomes Project) which will be enrolling patients with ICH, SAH
and SDH and following their outcomes at three months and one
year. Dr. Frontera is also launching a subarachnoid hemorrhage
MrI project where she will be looking at DWI/PWI changes from
admission through the vasospasm period and correlating these
findings to angiographic and clinical findings and outcomes. She
lectured at the 5th New York Symposium on Neurological
emergencies & Neurocritical Care meeting in June, passed the first
offered Neurocritical Care boards and is editor of the Patients and
Family Section of a new website launched by the Neurocritical
Care Society.
Scott Meyer, MD, PGY 5, has been selected as a “physician leader”
to serve on a committee regarding improving physician/patient
communication at Mount Sinai.
Dr. H. richard Winn was interviewed and answered callers’
questions in two separate sessions on the Greek radio station, first
6
On June 2, members of the Department of Neurosurgery and the Mount Sinai community, as well as friends,
colleagues and former faculty and residents from near and far, joined to honor Kalmon D. Post, MD, for his 17 years
as Chair of the Department of Neurosurgery at Mount Sinai. the tribute was in anticipation of Dr. Post’s stepping
down as Chair on July 1, 2008. Happily for the department, he will be staying on the faculty, continuing his active
surgical, teaching, and research schedule. the tribute included a scientific session during the day at the New York
Academy of Medicine and a gala dinner at the Yale Club in the evening. the morning’s scientific session featured
speakers who had worked with Dr. Post, who presently work with him and who had trained with him. the afternoon
session included three named lectureships as well as comments from Dean Kenneth Davis.
Morning speakers from Mount Sinai were Isabelle M. Germano, MD: The Mount Sinai Bench to Bedside Approaches to Primary Brain
Tumors; Aman B. Patel, MD: The Mount Sinai Experience in Carotid Artery Stenting; eliza B. Geer, MD: Body Composition in Cushing’s
Disease; ron L. Alterman, MD: Deep Brain Stimulation for Torsion Dystonia; H. richard Winn, MD: The Academic Legacy of Kalmon D.
Post, MD. Dr. Pamela Freda, Assistant Professor of Clinical Medicine at Columbia, who has been collaborating with Dr. Post since
1994 on patients with pituitary tumors of different types, spoke about Biochemical Criteria for Diagnosis and Remission of Acromegaly.
r. Michael Scott, MD, and Dr. Post were faculty members together at tufts in the 1970s. Dr. Scott, now a Professor and Director of
Clinical Pediatric Neurosurgery at the Boston Children’s Hospital, spoke about Cavernous Malformations in Children. Paul C.
McCormick, MD, Professor of Clinical Neurosurgery at Columbia university College of Physicians and Surgeons, was a resident at that
institution when Dr. Post was on the faculty there and discussed Dr. Post’s influence in his talk, Hemangioblastomas: What I Learned from
Kal Post. A faculty member at Mount Sinai from 1991 until 2000, Dr. Chandranath Sen is presently Chair of the Departments of
Neurosurgery at St. Luke’s-roosevelt Hospital Center and Beth Israel Medical Center. the title of his talk was Clival Chordomas: Clinical
Results and Complications.
In the afternoon, edward Laws, MD, who shares Dr. Post’s interest and expertise in neuroendocrine disorders, delivered the Ved P.
Sachdev, MD, Memorial Lecture, The Evolution of Pituitary Surgery. Dr. Laws recently joined the Department of Neurosurgery at
Brigham and Women’s Hospital in Boston. Following Dr. Laws, Peter J. Jannetta, MD, was the Leonard I. Malis, MD, Memorial
Lecturer. A pioneer in cranial nerve disorders and trigeminal neuralgia treatment, Dr. Jannetta is a Professor of Neurosurgery at
Allegheny General Hospital in Pittsburgh, Pennsylvania. His talk was titled Vascular Brainstem Compression: Changing Perceptions,
Changing Therapies. the last speaker of the day, rudolf Fahlbusch, MD, had traveled from Germany to honor his friend. Dr. Fahlbusch
presented the Jeannette and Bernard Post, MD, Memorial Lecture, Intraoperative Visualization of Brain Tumors.
Dr. Post and Dr. Ed Laws,
Dr. Peter Jannetta, Leonard I. Malis, MD, Memorial Lecturer,
Dr. Post and Dr. Rudolf Fahlbusch, Jeannette and
Ved P. Sachdev, MD, Memorial Lecturer
and Drs. Joshua Bederson, Kalmon Post, and Rudolf Fahlbusch
Bernard Post, MD, Memorial Lecturer
Drs. Kristjan Ragnarsson and Kal Post
Former resident Joseph Queenan, MD, Former resident Emily Friedman, MD,
and Dr. Isabelle Germano
and Linda Post
7
Drs. H. Richard Winn, Russel Patterson, Ed Laws
continued on page 8
Celebrating Career and Friendships
Recent Publications
Gandhi CD, Gilad r, Patel AB, Haridas A, Bederson JB. treatment of ruptured lenticulostriate artery aneurysms. J Neurosurg. 2008
Jul;109(1):28-37.
eloy JA, Carai A, Patel AB, Genden eM, Bederson JB. Combined endoscopic-assisted transclival clipping and endovascular stenting of a
basilar trunk aneurysm: case report. Neurosurgery. 2008 Mar;63(3 Suppl 1):142-3.
reis C, Genden eM, Bederson JB, Som PM. A rare spontaneous osteosarcoma of the calvarium in a patient with long-standing fibrous
dysplasia: Ct and Mr findings. Br J radiol. 2008 Feb;81(962):e31-4.
Bederson JB, Chair, Batjer HH, Conolly eS, Dacey rG, Duldner J, Diringer M, Harbaugh re, Dion JJ, Patel AB, rosenwasser rH,
Members. Guidelines for the management of aneurysmal subarachnoid hemorrhage. A statement for healthcare professionals from a
special writing group of the Stroke Council. American Heart Association. Stroke, 2008. In Press.
Post KD. Commentary. Surg Neurology. 2008 May 13.
Gandhi CD, Meyer SA, Patel AB, Johnson DM, Post KD. Neurologic complications of inferior petrosal sinus sampling. AJNr Am J
Neuroradiol. 2008 Apr;29(4)760-5.
Snyder, BJ, Naidich, tP, Post, KD. Cystic Lesions of the Sella. In: Swearingen, B, Biller, BMK (eds), Diagnosis and Management of
Pituitary Disorders. Humana Press, totowa, New Jersey, pp445-466, 2008.
Germano IM, uzzaman M, Keller G. Gene delivery by embryonic stem cells for malignant glioma therapy: Hype or hope? Cancer Biol
ther. 2008 Sept 11;7(9).[epub ahead of print]
uzzaman M, Keller G, Germano IM. In vivo Gene Delivery by embryonic stem cell-derived astrocytes for malignant gliomas. Neuro
Oncol. 2008 Aug 1. [epub ahead of print]
WINS White Paper Committee: Benzil DL, Abosch A, Germano I, Gilmer H, Maraire JN, Muraszko K, Pannullo S, rosseau G,
Schwartz L, todor r, ullman J, Zusman e. the future of neurosurgery: a white paper ono the recruitment and retention of women
in neurosurgery. J Neurosurg. 2008 Seep;109(3):378-386.
Britz G, Winn Hr. Assessing the constancy of intracranial aneurysm growth rates. J Neurosurg. 2008 Aug;109(2):173-4.
Miekisiak G, Kulik t, Kusano Y, Kung D, Chen JF, Winn Hr. Cerebral blood flow response on adenosine 2a receptor knockout mice
during transient hypoxic hypoxia. J Cereb Blood Flow Metab. 2008 June 11. [epub ahead of print]
Kulik t, Kusano Y, Aronhime S, Sandler AL, Winn Hr. regulation of cerebral vasculature in normal and ischemic brain.
Neuropharmacology. 2008 Sept;55(3):281-8.
Winn Hr. Brain abscess. Neurosurgery Focus. 2008;24(6)e1.
Dumitriu D, Collins K, Alterman r, Mathew SJ. Neurostimulatory therapeutics in management of treatment-resistant depression with
focus on deep brain stimulation. Mt. Sinai J Med. 2008 May-June;75(3):263-75.
Isaias Iu, Alterman rL, tagliati M. Outcome predictors of pallidal stimulation in patients with primary dystonia: the role of disease
duration. Brain. 2008 Jul;131(pt 7):1895-902.
Brozova H, Barnaure I, Alterman rL, tagliati M. the effect of 60Hz StN-DBS on gait and speech in patients with Parkinson’s Disease.
Movement Disorders 23(Suppl 1): S109, 2008.
tagliati M, Martin Ce, Alterman rL. Optimal pallidal stimulation frequency for dystonia may vary with age. Movement Disorders
23(Suppl 1):S113, 2008.
Alterman rL, tagliati M. Preparation for Movement Disorder Surgery. In Bakay rAe (ed). Movement Disorder Surgery- the essentials,
thieme, New York, 2008, pp58-69.
June 2, 2008, Yale Club, New York City
8
Gupta F, Chan N, Alterman rL, Walker r, tagliati M. DBS frequency screening for programming optimization in a patient with
chorea-acanthocytosis. Movement Disorders 23(Suppl 1):S384, 2008.
continued on page 10
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Recent Publications
continued from page 9
Alterman rL. Outcome measures for functional neurosurgery. Congress of Neurological Surgeons Quarterly, Spring 2008, pp31-34.
Gilad r, Gandhi CD, Johnson DM, Patel AB. Hyperfusion syndrome after external carotid artery stent placement in a case of bilateral
internal carotid occlusion and external carotid stenosis. J Vasc Interv radiol. 2008 Sep;19(9):1373-7.
Frontera JA, Parra A, Shimbo D, Fernandez A, Schmidt JM, Peter P, Claassen J, Wartenberg Ke, rincon F, Badjatia N, Naidich A,
Connolly eS, Mayer SA. Cardiac arrhythmias after subarachnoid hemorrhage: risk factors and impact on outcome. Cerebrovasc Dis.
2008;26(1):71-8.
Frontera JA, Fernandez A, Schmidt JM, Claassen J, Wartenberg Ke, Badjatia N, Parra A, Connolly eS, Mayer SA. Impact of nosocomial
infectious complications after subarachnoid hemorrhage. Neurosurgery. 2008 Jan;62(1):80-7.
Starke rM, Komotar rJ, Otten ML, Schmidt JM, Fernandez LD, rincon F, Gordon e, Badjatia N, Mayer SA, Connolly eS. Predicting
Long term Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage Patients utilizing the Glasgow Coma Scale (Accepted
Journal of Clinical Neuroscience)
Ohara S, Crone Ne, Weiss N, Kim JH, Lenz FA. Analysis of synchrony demonstrates that the presence of “pain networks” prior to a
noxious stimulus can enable the perception of pain in response to that stimulus. exp Brain res. 2008 Feb;185(2):353-8.
Freda Pu, Shen W, Heymsfield SB, reyes-Vidal CM, Geer eB, Bruce JN, Gallagher D. Lower visceral and subcutaneous but higher
intermuscular adipose tissue depots on patients with growth hormone and insulin-like growth factor I excess due to acromegaly. J Clin
endocrinol Metab. 2008 Jun;93(6):2334-43.
etz CD, Homann tM, Luehr M, Kari FA, Weisz DJ, Kleinman G, Plestis KA, Griepp rB. Spinal cord blood flow and ischemic injury after
experimental sacrifice of thoracic and abdominal segmental arteries.eur J Cardiothorac Surg. 2008 Apr 10. [epub ahead of print]
Halstead JC, Meier M, Wurm M, Zhang N, Spielvogel D, Weisz D, Bodian C, Griepp rB. Optimizing selective cerebral perfusion:
deleterious effects of high perfusion pressures.J thorac Cardiovasc Surg. 2008 Apr;135(4):784-91.
Gracies M, Lugassy M, Weisz DJ, Vecchio M, Flanagan S, Simpson DM. Botulinum toxin Dilution and endplate targeting in spasticity: A
double-blind controlled study. Archives of Physical Medicine and rehabilitation, accepted for publication.
Som PM, Park ee, Naidich tP, Lawson W. Crista galli pneumatization is an extension of the adjacent frontal sinuses. AJNr Am J
Neuroradiol. 2008 Sep 3 [epub ahead of print]
Delman BN, Fatterpekar GM, Law M, Naidich tP. Neuroimaging for the pediatric endocrinologist. Pediatr endocrinol rev. 2008 Feb;5
Suppl 2:708-19.
Zacharia tt, Law M, Naidich tP, Leeds Ne. Central nervous system lymphoma characterization by diffusion-weighted imaging and
Mr spectroscopy. J Neuroimaging. 2008 May 19. [epub ahead of print]
Lu H, Pollack e, Young r, Babb JS, Johnson G, Zagzag D, Carson r, Jensen JH, Helpern JA, Law M. Predicting Grade of cerebral glioma
using vascular-space occupancy Mr imaging. AJNr. 2008 Feb; 29(2):373-78.
Lui Y, Law M, Babb J, Johnson G, Gruber M, Chacko J, Allen J. Correlation of Diffusion tensor Metrics with Clinical Outcome in
Brainstem Gliomas. Neurosurgery 2008.
Lin K, Law M, Babb J, Pramanik NBK. Accuracy of the Alberta Stroke Program early Ct Score during the first 3-hours of middle cerebral artery stroke: comparison of noncontrast Ct, Ct angiography source images, and Ct perfusion. AJNr. 2008 Mar; 29(5):931-936.
Law M, Young r, Babb J, Peccerelli N, Chheang S, Gruber M, Golfinos J, Miller D, Zagzag D, Johnson G. Predicting time to progression
or survival in gliomas with cerebral blood volume measurements using dynamic susceptibility. radiology 2008 247:490-498.
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Announcements
Chen S. Chen, MD, and Martin Camins, MD, were selected for the recent
New York Magazine Castle Connolly Guide to Best Doctors in New York City.
Save the Dates
Radiosurgery Spine Symposium for
Patients and Caregivers
Spine Radiosurgery: New Hope for Cancer
Sidney A. Hollin, MD, Endowed Lecture
Wednesday, October 22, 2008
October 28, 2008
Brain AVMs: Endovascular Nidal Occulsion
Mount Sinai Hospital Goldwurm Auditorium
1480 Madison Avenue
and Paradigm Shift
in Multi-Modality Treatment
For more information on this event, call
Kathleen Maloney-Lutz, 212-241-5052
Aman Patel, MD, Associate Professor
Mount Sinai School of Medicine
Isabelle M. Germano, MD, Director
Annenberg 5 Boardroom
7:30 AM
October Grand Rounds
October 8: 7-8:50 AM: Quality Assurance: Mount Sinai Hospital
ron Alterman, MD, Department of Neurosurgery, Mount Sinai School of Medicine
October 15: 7-7:50 AM: Quality Assurance: elmhurst Queens Hospital
Jamie ullman, MD, Department of Neurosurgery, elmhurst Queens Hospital
8-8:50 AM: Practicing Excellence in Patient Care
Deborah Marin, MD, Medical Director, Physician Access Services, Mount Sinai School of Medicine
October 22: Sidney A. Hollin, MD, Memorial Lecture (see Save-the-Date on this page)
October 29: 7-7:50 AM: Clinical and Radiographic Comparison of Mini-Open TLIF to Open TLIF in 42 Patients with Long-Term
Follow Up
Sanjay Dhall, MD, Chief resident, Department of Neurosurgery, emory university School of Medicine
8-8:50 AM: Mount Sinai School of Medicine Master of Public Health Degree: Options for Resident and Fellow Physicians
emily Senay, MD, MPH, Master of Public Health Program, Mount Sinai School of Medicine
New Clinical Trial: Phase I trial of MPC-6827 and Carboplatin for the Management of relapsed Glioblastoma Multiforme
MPC-6827 is a drug that has a novel mechanism of action and is being studied here in patients who have relapsed or progressive glioblastoma.
this unique drug reaches a concentration 20-fold greater in brain tumor tissue than in blood and appears to be unusually effective in
shrinking tumors in experimental animals. When used with a platinum based drug like carboplatin, there appears to be a synergetic
response promoting an anti-tumor response. Appropriate patients for this protocol are individuals with glioblastoma who have not responded
to temodar and radiation. Prospective patients do not require further surgery but need to meet certain performance and health minima.
If you think that you may have an appropriate patient, please call robert Aiken, M.D. at 212-241-4503.
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