CV (March 2015) - Christopher Ing

Transcription

CV (March 2015) - Christopher Ing
University of Toronto,
Department of Biochemistry //
Molecular Structure and Function
The Hospital for Sick Children
686 Bay St.
Toronto, Ontario, M5G 0A4
(416)-813-6855
[email protected]
[email protected]
http://www.cing.net
CHRISTOPHER EDWARD ING
Education
Ph.D., Biochemistry. University of Toronto. 2012 – 2017.
Advisor: Dr. Régis Pomès
Thesis: Molecular basis of permeation and selectivity in voltage-gated sodium channels using
microsecond-scale molecular dynamics.
M.Sc., Physics. University of Waterloo. 2009 – 2011.
Advisor: Dr. Wing-Ki Liu and Dr. Pierre-Nicholas Roy
Thesis: Path integral Langevin dynamics of complex molecular systems: from low-temperature
quantum clusters to biomolecules
Hon.B.Sc., Computational Science. Co-Op. University of Waterloo. 2004 – 2009.
Specialization: Physics, Advisor: Dr. Jeffrey X.Y. Chen
Thesis: Mathematical Analysis of the Adhesion of Cylindrical Colloids in the Helfrich Model.
Contributions
Journal Articles
1. J. Little, G. Li, C. Ing, B. R. DiFrancesco, N. C. Bamford, H. Robinson, M. Nitz, R. Pomès, P.
L. Howell, “Modification and periplasmic translocation of the biofilm exopolysaccharide polyβ-1,6-N-acetyl-D-glucosamine” Proc. Natl. Acad. Sci., 111, 30 (2014).
2. M. Schmidt , S. Constable, C. Ing, P.-N. Roy, “Inclusion of trial functions in the Langevin
equation Path Integral Ground State method: application to parahydrogen clusters and their
isotopologues” J. Chem. Phys., 140, 234101 (2014)
3. N. Chakrabarti, C. Ing, J. Payandeh, N. Zheng, W.A. Catterall, R. Pomès, “Catalysis of Na+
Permeation in Bacterial Sodium Channel NaVAb” Proc. Natl. Acad. Sci., 110, 28 (2013).
4. S. Constable, M. Schmidt, C. Ing, T. Zeng, P.-N. Roy,
“Langevin Equation Path Integral Ground State”, J. Phys. Chem. A, 117, 32 (2013).
5. C. Ing, K. Hinsen, J. Yang, T. Zeng, H. Li, P.-N. Roy, “A path-integral Langevin equation
treatment of low-temperature doped helium clusters”, J. Chem. Phys., 136, 224309 (2012).
6. S. Mkrtchyan, C. Ing, and J.Z.Y. Chen, “Adhesion of cylindrical colloids on the surface of a
membrane”, Phys. Rev. E, 81, 1 (2010).
Supervision
2015 - Sanofi Biogenius Regional Competitors (two highschool students)
Directed research on the molecular simulation of intrinsically disordered peptides using
supercomputers, in accordance with a published protocol.
2015 – Biochemistry Undergraduate Research Project (undergraduate student)
Supervised research on the voltage-sensing domain of voltage-gated sodium channel using
MDAnalysis on multi-terabyte molecular dynamics datasets.
2014 – SickKids Summer Volunteers (two undergraduate students)
Utilized agile project management (PivotalTracker) to direct the tutorials, readings, research
summaries, software development, and scientific analysis using entirely iPython Notebooks. Original
contribution was prepared for Wikipedia.
Posters/Presentations
2015 – Nanometer-scale Pandas: A Data Science Approach to Structural Biology. PyCon 2015.
Montréal, QC, Canada. (poster),
2015 – Coupling of Channel Fluctuations in Ion Permeation and Selectivity in Bacterial Sodium
Channel NavAb. 59th Annual Meeting - Biophysical Society. Baltimore, MD, USA. (poster),
2014 – Catalysis and Selectivity of Na+ Permeation in the Bacterial Sodium Channel NavAb.
58th Annual Meeting - Biophysical Society. San Francisco, CA, USA. (poster),
2013 – Molecular Dynamics Simulations of Calcium Release Activated Channel Orai1.
Biochemistry Research Day, Toronto, ON, Canada (poster).
2012 – Ionic Diffusion in the Selectivity Filter of a NaV Channel. SickKids Research Institute
Retreat, Toronto, ON, Canada (poster).
2012 – Internal Hydration and Conformational Gating in Cytochrome c Oxidase. 56th Annual
Meeting - Biophysical Society. San Diego, CA, USA. (poster), 11th Chemical Biophysics
Symposium. Toronto, ON, Canada (poster).
2011 – Efficient Sampling of Quantum Systems Using Path Integral Molecular Dynamics:
Applications to Weakly Bound Systems and Biomolecules. 66th International Symposium on
Molecular Spectroscopy. Columbus, OH, USA (oral), 11th CERMM Symposium. Montreal, QC,
Canada. (oral). 27th Annual Symposium on Chemical Physics. Waterloo, ON, Canada. (poster).
2011 – Applications of Ring-Polymer Molecular Dynamics and Path Integral Ground State
Methods to He-CO2 and Biomolecules. 94th Canadian Chemistry Conference. Montreal, QC,
Canada (oral). Matrix 2011, Vancouver, BC, Canada (oral).
2011 – Sampling of Quantum Systems with Path Integral Langevin Dynamics: Applications to
Weakly Bound Clusters and Biomolecules. 10th Chemical Biophysics Symposium. Toronto, ON,
Canada. (oral), 17th Canadian Symposium on Theoretical Chemistry. Edmonton, AB, Canada.
(poster).
2010 – Path Integral Implementation in MMTK. Sharcnet Research Day 2010, Toronto, ON,
Canada. 10th CERMM Symposium. Montreal, QC, Canada. (oral).
Awards
2013 – University of Toronto Travel Scholarship, to deliver presentation at Biophysical Society 2014
2011 – MITACS Travel Scholarship, to deliver oral presentation at Matrix 2011
2010 – French Consulate Scholarship, to perform research at Synchrotron Soleil
Work
Experience
Action Potential Lab, Toronto, Canada
2014-Present – Lecturer, Course Content Creator, Demonstrator
Developed original art and science courses/workshops for children to adults on topics like “Cow
Eyeball Dissection”, “Sew-Your-Own-Cells”, and the “Science of Sound”. Acted as instructor for
multiple events, filmed for segment on YTV during Toronto Mini-Maker Faire 2014 during
“Oobleck on Speaker” demonstration, and prepared original scientific art to help lessons.
General Electric / SmallGirlsPR, New York, USA
2014 – Fashion Reporter
Photographed runway shoots and wrote technical scientific content at New York Fashion Week on
the General Electric Tumblr blog. All 16 articles received 3.5M+ impressions with 20,000 likes.
Department of Biochemistry, University of Toronto, Canada
2013/2014 – Exam Invigilator
Proctored final examinations of undergraduate Biochemistry courses.
Department of Physics and Astronomy, University of Waterloo, Canada
2011 – Teaching Assistant and Laboratory Instructor.
Lead weekly tutorials for first year Calculus students (>50 students). Acted as a lab demonstrator for
general physics and teaching assistant for first-year scientific computing. Marked assignments
upper-level undergraduate and graduate physics courses.
Synchrotron Soleil, Saint-Aubin, France
2010 – Scientific Programmer. Supervisor: Dr. Konrad Hinsen.
Implemented normal mode path integral molecular dynamics in MMTK, an open-source molecular
dynamics package. Benchmark study submitted as a peer-reviewed manuscript. Utilized Cython.
KDE / Google, Online
2009 – Google Summer of Code Developer. Supervisor: Vladimir Kuznetsov.
Implemented a real-time smoothed particle hydrodynamics algorithm in Step, an open-source
physics sandbox in the KDE education packages. Written in C++/Qt.
Radiation Laboratory, University of Notre Dame, U.S.A.
2008 – Computational Chemist. Supervisor: Dr. Daniel Chipman, Dr. Paulo R.C Couto.
Analyzed the many-body effects of hydroxyl-water clusters using a many-body decomposition
scheme with Gaussian/Fortran workflow. Compared many-body effects of pure water clusters to
those containing hydroxyl radicals.
Cardiac Imaging Group, Sunnybrook Hospital, Canada
2007 – Medical Imaging Developer. Supervisor Dr. Bonny Biswas, Dr. Graham Wright.
Contributed to C++ project for real-time MR imaging by adding new catheter tracking functionality.
Bioinformatics Group, Microarray Centre, Canada
2007 – Research Intern. Supervisor: Carl Virtanen.
Developed a statistical research tool in C# for visualizing gene ontology in expression data sets.
Wrote Perl scripts for sequence alignment, annotation of genes, and MySQL database integration.
Volunteering
2015 – Mozilla Science Lab, project lead for open-source web application development
2014 – Subtle Technologies Festival, gallery attendant and auditorium assistant
2014 – The Nepali Children's Education Project, charity event sports photographer
2011/2013/2014 – TEDxWaterloo, TEDxToronto, social media representative and floor volunteer
2013-2014 – Le Milieu, web administrator
2012/2013 – PyCon Canada, speaker liaison and introducer
2012 – Hacking Health Conference, reception DJ using Ableton Live
2011 – Graduate Student Research Conference, chemistry session chair
2010/2013 – Science Rendezvous, oobleck, interactive molecular dynamics demonstrator.
2009-2015 – Fresh Photons, image blogger (http://www.freshphotons.com)