Graduate School of Interdisciplinary New Science Toyo University

Graduate School of Interdisciplinary New Science Toyo University

Global Excellence in Action Graduate School of Interdisciplinary New Science Toyo University Graduate School of Interdisciplinary New Science Toyo University 2100, Kujirai, Kawagoe, Saitama 350-­‐8585, Japan Tel: +81 49 239 1313 Fax: +81 49 231 5117 E-­‐mail: [email protected] URL: http://www.toyo.ac.jp/site/english-­‐glns/ Course of Bio-­‐Nano Science Fusion Graduate School of Interdisciplinary New Science Toyo University Foreword Following the great success of the Doctoral Course, which was opened in April 2007, the Graduate School of Interdisciplinary New Science, Toyo University, started the Bio-­‐Nano Science Fusion Master Course in April 2011. Its aim is to surge ahead in bio and nanotechnology research, creating new interdisciplinary realms. We provide a unique curriculum such as Workshops on advanced equipment and Web educational programmes as well as lectures. The Graduate School also organises international symposia and seminars for young researchers. The students carry out advanced research on nanoscience/nanotechnology, bioscience/biotechnology and bio-­‐nano fusion in collaboration with the Bio-­‐Nano Electronics Research Centre, Toyo University. Supervisors Tatsuro Hanajiri Design and fabrication of Hisao Morimoto Self-­‐organisation/nonlinear dynamics of nano/micro materials nanoscale electron devices I am currently studying the physics of nanoscale electron devices and am interested in its application to nanoelectronics. I have studied the electric properties of thin SOI films and the structures of SOI MOSFETs with decanano scale gates. I propose fully inverted (FI) SOI MOSFETs with ultra-­‐thin SOI films and novel fully depleted (FD) SOI MOSFETs. Sakthi Kumar Bio-­‐nano fusion/nanotechnology/ biomaterials I am interested in the research work based on fusion of different science fields, namely physics, chemistry and biotechnology. I focus on research themes such as (a) Nano drug delivery, aptamer (DNA and RNA based) sensors and bio/chemical sensors. (b) Carbon nanotubes, nano particles and quantum dots for solar cell applications and plasma processing thin films. I am interested in self-­‐organisations, phase transitions, and non-­‐linear dynamics of nano/micro materials disperse systems such as suspensions, in which nano/micro particles, carbon nanotubes, fullerenes or biological cells are dispersed. I am also interested in bio-­‐nano fusion technologies utilising the above phenomena induced in nano/micro materials disperse systems. Yoshikata Nakajima Nanotechnology/Nanomaterials Bio-­‐nano fusion I am interested in advanced materials for future electron devices such as silicon-­‐on-­‐insulator (SOI) wafers, silicon-­‐on-­‐quartz (SOQ) and silicon nano dots, and micro-­‐particles and biological cells dispersed in solution. My study also focuses on the design and fabrication of high-­‐resolution bio-­‐nano analytical systems by utilising the advanced materials. Toru Mizuki Bio-­‐nano fusion/Biotechnology I am interested in the interactions between biomolecules such as protein, peptide and DNA, and nano/micro materials such as CNTs, fullerenes and magnetic materials. I am currently focusing on bio-­‐nano fusion research such as analysis of the function of proteins immobilised on nano/micro materials and acceleration of the enzyme activity using a rotational magnetic field. Global Excellence in Action Graduate School of Interdisciplinary New Science Toyo University Admission policy The Graduate School of Interdisciplinary New Science, Toyo University, accepts motivated Master and Doctor Course students from all over the world and creates internationally advanced researchers in the fields of bioscience, nanotechnology and bio-­‐nano fusion science and technology, the latter being one of the most important subjects in the 21st Century. Supervisors Takashi Uchida Akira Inoue Growth and application of carbon-­‐based nanostructures Extremophiles Fusion of biomolecules/nanoparticles I am interested in the research work related to carbon-­‐based nanostructures such as carbon nanotubes, carbon nanowalls and endohedral fullerenes. I focus on research themes such as (a) Equipment development-­‐chemical vapour deposition systems, electron cyclotron resonance ion source. (b) Growth-­‐carbon nanotubes, carbon nanowalls, endohedral fullerenes. I am interested in microorganisms (extremophiles) living under extreme environments such as high temperature, alkaline pH, organic solvents etc. These microorganisms have high potential activities producing new enzymes and decomposing chemical substances. I am also focusing on the fusion of biotechnology and nanotechnology. Usami Ron Screening and application of Toru Maekawa Extremophiles are microorganisms which grow in extreme environments where other organisms are difficult to survive. A great attention has recently been paid to extremophiles extremophiles. I am developing several new methodologies for isolating valuable microorganisms and carrying out analysis of their functions and genes. Self-­‐organisation/self-­‐assembly in nano/micro systems I am very much interested in pattern formations, synchronisation and chaos created via self-­‐organisation/self-­‐assembly, which are induced in nano/micro systems. Fluctuations, surface effects and quantum effects, in particular, become significant on nanometre scales, which makes nano systems completely different from our macroscopic world. Visiting Professors Sir Harry Kroto Florida State University Daniel Morse UCSB Sir John Walker Régine Perzynski University of Cambridge Université Paris 6 Raymond Whitby Nicole Grobert University of Oxford University of Brighton P.V. Mohanan Sree Chitra Tirunal Institute for Medical Sciences and Technology Leonid Kalachev University of Montana Yoshio Bando NIMS Toru Kobayashi JAMSTEC Shigeru Deguchi JAMSTEC Course of Bio-­‐Nano Science Fusion Graduate School of Interdisciplinary New Science Toyo University Curriculum (Master Course) Year Type Lectures 1 Workshops Web programme Research Web programme 2 Research Title Units Introduction to bio-­‐nano science fusion 2 English for science and technology 2 Fundamental mathematics 2 Fundamental physics 2 Fundamental chemistry 2 Fundamental biotechnology 2 Extremophiles 2 Nanoelectronics 2 Nano materials 2 Bio materials and nanotechnology 2 Microbiology 2 Bio nano science 2 Advanced nano science and nanotechnology 2 Workshop on advanced equipment I 2 Workshop on advanced equipment II 2 Workshop on advanced equipment III 2 Workshop on advanced equipment IV 2 Web education I 2 Bio-­‐nano science fusion seminar I and II 4 Bio-­‐nano science fusion research I and II 4 Web education II 2 Bio-­‐nano science fusion seminar III and IV 4 Bio-­‐nano science fusion research III and IV 4 Web educational programmes: GEOSET TOYO We produce in collaboration with Sir Harry Kroto web educational programmes named “Global Educational Outreach for Science, Engineering and Technology, Toyo University” abbreviated to “GEOSET TOYO”. Students also participate in the production of GEOSET TOYO programmes. Some typical programmes are listed below; Type
Programmes Level Lecture + ppt + video Lecture + ppt + video Lecture + ppt + video Lecture + ppt Experiment + ppt + video Experiment + ppt + video Seminar + ppt + video Seminar + ppt + video Video Video Video Fundamental science: Classical mechanics (Outline, philosophy, history) Fundamental science: Classical mechanics (Experimental verification) Fundamental science: Electromagnetism (Outline, philosophy, history) Fundamental science: Electromagnetism (Maxwell equation) Observation of nanostructures by electron microscopes Observation of nanostructures by scanning probe microscopes Room temperature growth of compound semiconductors learning from sea creatures Professor Daniel Morse Sir Harry Kroto’s International Seminar for Young Scientists Introduction to California NanoSystems Facilities and equipment Visit to the Royal Society Great scientists Sir Harry Kroto’s Seminar for Junior Students Undergraduate (UG) Graduate (Grad) UG, Grad UG, Grad UG, Grad, PD UG, Grad, PD UG, Grad, PD UG, Grad, PD, Researchers (R) UG, Grad, PD, R UG, Grad, PD, R UG, Grad, PD, R Primary, Junior-­‐high and High School Global Excellence in Action Graduate School of Interdisciplinary New Science Toyo University Facilities and equipment State-­‐of-­‐the-­‐art facilities and equipment are installed at the Bio-­‐Nano Electronics Research Centre, which Master and Doctor Course students can use for their research. A unique course such as “Workshops on advanced equipment” is included in the curriculum for Master Course students.
Nanostructures Processing Room Lithography Room Nanoelectronics Super Clean Rooms Incubation Laboratory Transmission Electron Microscope SQUID Biotechnology Clean Rooms DNA Sequencer Scanning Electron Microscopes Scanning Probe Microscope Course of Bio-­‐Nano Science Fusion Graduate School of Interdisciplinary New Science Toyo University Events The Graduate School organises and holds international symposia, seminars, workshops, etc. for the students. The students also participate in the events; e.g., they present their latest results at international symposia and seminars.
International Symposia on Bioscience and Nanotechnology International Seminars for Young Scientists (overseas) International Seminars for Young Scientists (Kawagoe Campus) Global Excellence in Action Graduate School of Interdisciplinary New Science Toyo University Sir Harry Kroto’s Seminars for Young Scientists (Kawagoe Campus) Recent publications Nanoscience/nanotechnology
A.C. Poulose, S. Veeranarayanan, M.S. Mohamed, Y. Nagaoka, R.R. Aburto, T. Mitcham, P.M. Ajayan, R.R. Bouchard, Y. Sakamoto, Y. Yoshida, T. Maekawa and D.S. Kumar, Multi-­‐stimuli responsive Cu2S nanocrystals as trimodal imaging and synergistic chemo-­‐photothermal therapy agents, Nanoscale 7, 8378-­‐8388 (2015). DOI: 10.1039/C4NR07139E N. Chauhan, V. Palaninathan, S. Raveendran, A.C. Poulose, T. Nakajima, T. Hasaumra, T. Uchida, T. Hanajiri, T. Maekawa and D.S. Kumar, N2-­‐plasma assisted one-­‐step alignment and patterning of graphene oxide on SiO2/Si substrate via Langmuir-­‐Blodgett technique, Adv. Mater. Interfaces 2, 1400515 (2015). DOI: 10.1002/admi.201400515 A. Baliyan, Y. Nakajima, T. Fukuda, T. Uchida, T. Hanajiri and T. Maekawa, Synthesis of an ultradense forest of vertically aligned triple-­‐walled carbon nanotubes of uniform diameter and length using hollow catalytic nanoparticles, J. Am. Chem. Soc. 136, 1047-­‐1053 (2014). DOI: 10.1021/ja410794p T. Yamada, T. Hanajiri and T. Toyabe, Modeling of drain electric flux passing through the BOX layer in SOI MOSFETs -­‐ Part I: Preparation for modeling based on conformal mapping, IEEE Trans. Electron Devices 61, 3023–3029 (2014). DOI: 10.1109/TED.2014.2325595 Bioscience/biotechnology H. Shimoshige, H. Kobayashi, T. Mizuki, Y. Nagaoka, A. Inoue and T. Maekawa, Effect of polyethylene glycol on the formation of magnetic nanoparticles synthesized by Magnetospirillum magnetotacticum MS-­‐1, PLoS One 10, e0127481 (2015). DOI: 10.1371/journal.pone.0127481 N. Doukyu, S. Nihei. Cholesterol oxidase with high catalytic activity from Pseudomonas aeruginosa: Screening, molecular genetic analysis, expression and characterization, J. Biosci. Bioeng. (2015), at press. DOI: 10.1016/j.jbiosc.2014.12.003 R. Watanabe and N. Doukyu, Improvement of organic solvent tolerance by disruption of the lon gene in Escherichia coli, J. Biosci. Bioeng. 118, 139-­‐144 (2014). DOI: 10.1016/j.jbiosc.2014.01.011 Bio-­‐nano fusion science/technology B. Sivakumar, R.G. Aswathy, Y. Nagaoka, T. Fukuda, S. Iwai, K. Venugopal, K. Kato, T. Maekawa and D.S. Kumar, An ‘all in one’ approach for simultaneous chemotherapeutic, photothermal and magnetic hyperthermia mediated by hybrid magnetic nanoparticles, RSC Adv. 5, 25066-­‐25078 (2015). DOI: 10.1039/C5RA00168D M.S. Mohamed, S. Veeranarayanan, H. Minegishi, Y. Sakamoto, Y. Shimane, Y. Nagaoka, A. Aki, A.C. Poulose, A. Echigo, Y. Yoshida, T. Maekawa and D.S. Kumar, Cytological and subcellular response of cells exposed to the type-­‐1 RIP curcin and its hemocompatibility analysis, Sci. Rep. 4, 5747 (2014). DOI: 10.1038/srep05747 S. Raveendran, A.R. Girija, S. Balasubramanian, T. Ukai, Y. Yoshida, T. Maekawa and D.S. Kumar, Green approach for augmenting biocompatibility to quantum dots by extremophilic polysaccharide conjugation and nontoxic bioimaging, ACS Sustainable Chem. Eng. 2, 1551–1558 (2014). DOI: 10.1021/sc500002g S. Balasubramanian, A.R. Girija, R. Sreejith, Y. Nagaoka, S. Iwai, M. Suzuki, T. Fukuda, T. Hasumura, Y. Yoshida, T. Maekawa and D.S. Kumar, Bacterial exopolysaccharide based magnetic nanoparticles: A versatile nanotool for cancer cell imaging, targeted drug delivery and synergistic effect of drug and hyperthermia mediated cancer therapy, J. Biomed. Nanotechnol. 10, 885-­‐899 (2014). DOI: 10.1166/jbn.2014.1820 Course of Bio-­‐Nano Science Fusion Graduate School of Interdisciplinary New Science Toyo University Awards and prizes ✓ Best Poster Award (2014) S. Raveendran, N. Chauhan, V. Palaninathan, T. Maekawa and D.S. Kumar, Cancer therapy based on shape dependent biocompatible gold hybrid nanostructures, The 9th International Conference on Surfaces, Coatings and Nanostructured Materials (NANOSMAT 2014) (2014), Dublin, Ireland. ✓ IUPAC Young Researcher Award (2013) S. Veeranarayanan, M.S. Mohamed, A.C. Poulose, N. Hirosawa, Y. Sakamoto, Y. Yoshida, T. Maekawa and D.S Kumar, Synergistic targeting of cancer and associated angiogenesis In vivo using triple-­‐targeted drug loaded silica nanoformulations for theragnosticst, International Conference on Frontiers of Polymers and Advanced Materials (ICFPAM-­‐2013) (2013), Auckland, New Zealand. ✓ IUPAC Young Researcher Award (2013) M.S. Mohamed, S. Veeranarayanan, A.C. Poulose, Y. Nagaoka, Y. Yoshida, T. Maekawa and D.S Kumar, Fe3O4 core-­‐silica shell nanoclusters based multimodal treatment strategy for drug resistant breast cancers, International Conference on Frontiers of Polymers and Advanced Materials (ICFPAM-­‐2013) (2013), Auckland, New Zealand. ✓ Tasilo Prnka Prize (2012) S. Veeranarayanan, A.C. Poulose, M.S. Mohamed, Y. Nagaoka, S. Kashiwada, Y. Yoshida, T. Maekawa and D.S. Kumar, Nanoformulation facilitated disruption of vasculogenesis: Approach towards neo-­‐angiogenic treatment, Nanocon 2012, C13 (2012), Brno, Czech Republic. Highlighted papers ✓ ACS Editors’ Choice, American Chemical Society (2014) A. Baliyan, Y. Nakajima, T. Fukuda, T. Uchida, T. Hanajiri and T. Maekawa, Synthesis of an ultradense forest of vertically aligned triple-­‐walled carbon nanotubes of uniform diameter and length using hollow catalytic nanoparticles, J. Am. Chem. Soc. 136, 1047-­‐1053 (2014). DOI: 10.1021/ja410794p ✓ Spotlights on Recent JACS Publications, American Chemical Society (2014). A. Baliyan, Y. Nakajima, T. Fukuda, T. Uchida, T. Hanajiri and T. Maekawa, Hollow Spheres Lend Control to Carbon Nanotube Growth, J. Am. Chem. Soc. 136, 1157 (2014). DOI: 10.1021/ja500664b ✓ Institute of Physics (2012) S. Veeranarayanan, A.C. Poulose, S. Mohamed, A. Aravind, Y. Nagaoka, Y. Yoshida, T. Maekawa and D.S. Kumar, FITC labeled silica nanoparticles as efficient cell tags: Uptake and photostability study in endothelial cells, J. Fluoresc. 22, 537–548 (2012). DOI: 10.1007/s10895-­‐011-­‐0991-­‐3 Secretariat of the Graduate School of Interdisciplinary New Science, Toyo University Yuko Tsuburaya
Katsumi
Funato Narutoshi Fukushima Natsue Takahashi
Secretariat of the Bio-­‐Nano Electronics Research Centre, Toyo University Minako Hardy
Mikiko Koizumi
Sachiko Takahashi
Hiroshi Akasu
Akiko Tanaka
Enquiries concerning the graduate school Graduate School of Interdisciplinary New Science Education and Student Affairs Section, Kawagoe Campus, Toyo University 2100, Kujirai, Kawagoe, Saitama 350-­‐8585, Japan +81-­‐49-­‐239-­‐1313, Fax: +81-­‐49-­‐231-­‐5117, E-­‐mail: [email protected] Tel: URL: http://www.toyo.ac.jp/site/english-­‐glns/ Enquiries concerning research projects Bio-­‐Nano Electronics Research Centre, Toyo University Research Promotion Section 2100, Kujirai, Kawagoe, Saitama 350-­‐8585, Japan Tel: +81-­‐49-­‐239-­‐1375, Fax: +81-­‐49-­‐234-­‐2502, E-­‐mail: [email protected] URL: http://www.toyo.ac.jp/site/bionano/