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WINTER 2006-07 Biofuels T H E S TAT E O F RENEWABLE ENERGY RESEARCH AT THE UNIVERSITY PUTS MINNESOTA AT AN ADVANTAGE, BUT WILL THE STATE REMAIN COMPETITIVE? SEE STORY ON PAGE 8. RESEARCH NEWS CLASS NOTES DONOR HONOR ROLL F R O M T H E D E A N What are you DRIVEN TO DISCOVER? THIS FALL THE UNIVERSITY LAUNCHED A PROMOTIONAL CAMPAIGN CALLED DRIVEN TO DISCOVER TO HELP PEOPLE UNDERSTAND HOW WE, AS THE ONLY PUBLIC RESEARCH INSTITUTION IN THE STATE, CONTRIBUTE TO QUALITY OF LIFE IN MINNESOTA, AND JUST HOW RELEVANT AND INTERESTING RESEARCH CAN BE. THE CAMPAIGN, WHICH GREW OUT OF THE STRATEGIC POSITIONING PROCESS, ALSO SERVES TO RALLY MINNESOTANS AROUND THE UNIVERSITY’S GOAL OF BECOMING A LEADING RESEARCH INSTITUTION. I can’t imagine a more fitting slogan for the University of Minnesota. “Driven” captures the passionate Robert Elde, Dean pursuit of science and “Discover” is so much more tantalizing and evocative than its cousin, “Research.” There’s a reason why the Discovery Channel isn’t called the Research Channel … WINTER 2006-07 Vol. 5 No. 2 Robert Elde Dean Huber Warner Associate Dean Robin Wright Associate Dean Elizabeth Wroblewski Chief Administrative Officer Peggy Rinard Communications Director Stephanie Xenos Editor Jack El-Hai Mary Hoff Peggy Rinard Stephanie Xenos Writers Shawn Welch I like the interactive nature of the campaign because it opens the door to the academy and invites people in for a friendly chat and look around the place. It makes it clear that all visitors and all questions are welcome. It captures the unique combination of our Minnesota work ethic and creativity. It would have worked 100 years ago as well as it does today. And I suspect it will make sense as long as discoveries remain to be made. In short, to borrow another brand, it’s the real thing. The campaign began by featuring people asking their “single greatest questions,” which were fielded by University researchers. In the first round, David Tilman addressed the question “Can we end our dependence on foreign oil?” and Daniel Bond responded to “What’s the next alternative energy source?” You may have seen the print ads and TV commercials. I am pleased that two CBS faculty were invited to help launch the campaign and I see this as the beginning of a long and productive relationship. “Driven to Discover” is more than a slogan. It’s a new way of talking about ourselves and interacting with our stakeholders. It will be part of the identity and life of the University for a long time to come. The campaign couldn’t be a better vehicle for communicating about CBS research and education to the public. This issue of BIO provides many examples of our drive to discover, from faculty pursuing sustainable ways to provide energy to recent graduate Mohamed Abdihalim, whose quest led him from a refugee camp in Kenya to the University’s Medical School. Graphic Designer Tim Rummelhoff Photographer Laurie Hennen Development Director Jean Marie Lindquist Administrative Assistant Robert Elde, Dean College of Biological Sciences [email protected] U of M Printing Services Printing Visit our Web site at www.cbs.umn.edu. For address changes, please contact Jean Marie Lindquist at [email protected] or 612-625-7705. COLLEGE OF BIOLOGICAL SCIENCES T A B L E O F C O N T E N T S In this issue WINTER 2006-07 In Every Issue 2 ABSTRACTS Fungi study gives insights into evolution… ecologist wins Packard prize… plant diversity boosts bug diversity… a genetic cause for hyperactivity 4 CBS NEWS Cedar Creek makeover… new Norwegian chair… $1 million for grad education… a fitting memorial 16 6 THE ROLE OF ROT 8 POWER FROM THE PRAIRIE GIVING BACK Making your contributions count 17 ALUMNI NEWS Class Notes… Calendar 22 BACK PAGE Fill your tank with prairie grass Cover Story 8 THE STATE OF BIOFUELS Research supported by the University of Minnesota’s Initiative for Renewable Energy and the Environment has helped the state position itself as a biofuels leader. But will Minnesota stay ahead of the curve? Features 6 7 13 14 15 18 FIELD NOTES— Decomposition PLANT BIOLOGY— Plant evolution and global warming GENETICS— Yeasty inquiries STRUCTURAL BIOLOGY— Seeing proteins STUDENT LIFE— Refugee to medical student DONOR HONOR ROLL The University of Minnesota is committed to the policy that all persons shall have equal access to its programs, facilities, and employment without regard to race, color, creed, religion, national origin, sex, age, marital status, disability, public assistance status, veteran status, or sexual orientation. Printed on elementally chlorine-free recycled paper containing 20 percent post-consumer waste. Cover photo by G. Arnell Williams 15 A SENSE OF RESPONSIBILITY BIO is published two times a year by the University of Minnesota College of Biological Sciences for alumni, faculty, staff, and friends of the College. It is available in alternative formats upon request; please call 612-624-8723 or fax 612-624-2785. BIO ❚ WINTER 2006-07 a b s t r a c t s ecology and evolution New glimpse into EVOLUTION OF LIFE ON EARTH s early fungi made the evolutionary journey from water to land and branched off from animals, they shed tail-like flagella that propelled them through their aquatic environment and evolved new mechanisms (including explosive volleys and fragrances) to disperse spores and multiply. “What’s particularly interesting is that species retained their flagella for different lengths of time and developed different mechanisms of spore dispersal,” says David McLaughlin, professor of plant biology and co-author of a paper published in the October 19 issue of Nature describing how fungi adapted to life on land. The discovery provides a new glimpse into the evolution of life on Earth. It also helps scientists better under- stand this unusual group of organisms and learn how to develop uses for their unique properties in medicine, agriculture, conservation and industry. The discovery is the latest installment in an international effort to learn the origins of species. McLaughlin is one of five principal investigators leading a team of 70 researchers at 35 institutions. The group analyzed information from six key genetic regions in almost 200 contemporary species to reconstruct the earliest days of fungi and their various relations. The work is funded by a $2.65 million “Assembling the Tree of Life” grant from the National Science Foundation that was awarded to Duke University, the University of Minnesota, Oregon State University and Clark University in January 2003. TIM RUMMELHOFF A David McLaughlin was co-author of a paper in Nature describing how mushrooms adapted to life on land. In 1998, scientists discovered that fungi split from animals nine million years after plants did, which means that fungi are actually more closely related to animals than to plants. ECOLOGIST’S WINNING WORK ON MECHANISMS THAT CONTROL BIODIVERSITY Helene Muller-Landau, assistant professor of Earlier this year, Muller-Landau and colleagues ecology, evolution and behavior, has been awarded a $625,000 fellowship from the Packard Foundation to study mechanisms that control biodiversity in tropical forests, and how human impact—including global climate change—affects those mechanisms. published a pair of papers presenting new theories for tropical tree growth, mortality and forest structure that she developed and tested on more than two million trees from 14 sites around the world. Muller-Landau is one of 20 scientists and engineers selected for the 2006 awards, which recognize the most promising young faculty in the United States. The Packard Foundation solicited the nominations from 50 leading U.S. research universities. Helene Muller-Landau is the third CBS faculty member to receive a Packard Fellowship, which recognizes the nation’s most promising young scientists. 2 COLLEGE OF BIOLOGICAL SCIENCES She is the third College of Biological Sciences faculty member to receive a Packard Fellowship in the past several years. Others are George Weiblen, plant biology, and Claudia Schmidt-Dannert, biochemistry, molecular biology and biophysics. “According to these studies, there is no one-sizefits-all approach for tropical forests,” says MullerLandau. “The observed patterns not only deviate substantially from the supposedly universal rules predicted by current ecological theory, but also differ significantly among sites.” The David and Lucile Packard Foundation was created in 1964 by David Packard, the co-founder of the Hewlett-Packard Company, and his wife, Lucile Salter Packard. MORE PLANTS, MORE BUGS Since Darwin landed in the Galapagos, biologists have wondered why there are so many different kinds of bugs in the tropics. But now a team of researchers from the University of Minnesota, the University of South Bohemia and the Smithsonian Institute for Tropical Research has ended the speculation. Simply put, it’s because there are so many kinds of plants. The team disproved a more complex explanation, which suggested that tropical bugs dined on fewer plants (were more host specific) than their temperate-zone cousins. In fact, the researchers showed that tropical and temperate bug species feed on the same number of plant species, despite the smorgasbord of choices in the tropics. George Weiblen, associate professor of plant biology, was principal investigator of the National Science Foundation grant that funded the study, which was carried out in the Czech Republic, Slovakia and Papua New Guinea. The research was published in the August 25 issue of Science. EVOLUTIONARY HISTORY MAY GUIDE ECOSYSTEM RESTORATION Evolutionary history plays an important role in determining community structure, according to a recent study led by Jeannine Cavender-Bares, Department of Ecology, Evolution and Behavior. “This has important implications for ecological restoration,” Cavender-Bares says. ”If species show deterministic patterns of assembly into communities, this provides guidelines for how to restore communities that have been disturbed by humans.” The study, “Phylogenetic structure of Floridian plant communities depends on taxonomic and spatial scale,” was published in the July issue of Ecology. h u m a n h ea lt h RESEARCHER DEVELOPS MOUSE MODEL FOR MUSCLE DISEASE James Ervasti and his team have identified the importance of a gene critical to normal muscle function. The researchers “knocked out” the gene in mice that encodes the protein gamma actin found in normal muscle cells. The result: a mouse model for centronuclear myopathy, a poorly understood muscle disease similar to muscular dystrophy. The finding is published in the September issue of Developmental Cell. Ervasti is professor of biochemistry, molecular biology and biophysics. POSSIBLE GENETIC CAUSE FOR HYPERACTIVITY DISCOVERED In a first-of-its-kind, large-scale screening for disease traits, University researchers used a genetic tool called the Sleeping Beauty Transposon system to randomly mutate genes in mice and then pinpoint a possible genetic cause of hyperactivity. “It is our hope that similar research could lead to advances in understanding human behavior and the development of medications that target the genetic causes of many diseases,” says David Largaespada, associate professor of genetics, cell biology and development, who is lead author of the study. The finding is published in the September issue of Public Library of Science Genetics. MOLECULAR STRUCTURE OF FLAGELLA NOW SHOWING IN 3-D Mary Porter, professor of genetics, cell biology and development, is co-author of a paper in the August 18 issue of Science describing a new technique that provides a 3-D glimpse of the molecular structure of the flagellum, a tail-like organelle that enables cell motility and signaling. Defective flagella have been linked to infertility, chronic respiratory disease and polycystic kidney disease, among other conditions. Consequently, getting a close look at how the organelle is assembled will help scientists understand how these diseases occur. The researchers used cryopreservation and high-resolution tomography to obtain exceptionally clear and detailed images. The title of the paper is “The molecular architecture of axonemes revealed by cryo-electron tomography.” BIO ❚ WINTER 2006-07 3 c b s n e w s CEDAR CREEK MAKEOVER UNDERWAY Cedar Creek Natural History Area is busier than usual with construction on a new interpretive center and housing for students and visiting faculty. Construction workers broke ground at the field station September 21. The new Norwegian chair facilities will make it possible “to show people what we’re doing and why it’s important,” says The new Science and Professor David Tilman, Interpretive Center will provide who has conducted labs, classrooms, an exhibit hall and a biodiversity garden. groundbreaking research at Cedar Creek for more than two decades. The $7 million expansion will add 22,000 square feet of space. Construction will be completed in spring 2007. CBS is also exploring opportunities to take advantage of advances in field Architects Rafferty Rafferty and Tollefson designed the Visitors Center at the Landscape Arboretum. research technology that are creating multiinvestigator research opportunities spanning the physical, biological and computational sciences and engineering. These include climate, microbial biology, biofuels, eco-informatics and environmental observatories. Judd Sheridan and Odd Jarle Skejlhaugen will share the Norway chair. IN BIOENERGY AND FOOD SAFETY ANNOUNCED J udson Sheridan, College of Biological Sciences, and Odd Jarle Skjelhaugen, Norwegian University for Life Sciences, will share the Norwegian Centennial Interdisciplinary Chair and oversee an international research collaboration. Sheridan is director of international programs and professor of genetics, cell biology and development. Skjelhaugen is director of research and professor of environmental engineering. The chair was created with a $750,000 gift from Norway, presented by Crown Prince Haakon when he visited the University of Minnesota to celebrate Norway’s centennial last fall. The University of Minnesota matched the gift with $750,000 from the Permanent University Fund. CBS will raise funds for graduate fellowships. “THE RESEARCH FOCUSES ON SOME OF THE MOST PRESSING ISSUES FACING THE WORLD.” —Judson Sheridan According to Sheridan: “The research projects currently underway and soon to be initiated focus on some of the most pressing issues facing Norway, Minnesota and, in fact, the world. We expect the results from the research to advance our basic knowledge at the frontiers while developing practical and economical approaches to dealing with these problems. Advances in using biofuels, developing bio-based products and applying functional genomics can have a huge impact on our environment, the cost of energy and even the safety of our food.” Sheridan and Skjelhaugen will use the endowment earnings to support faculty and student exchanges and to develop new research collaborations. U AWARDS CBS $1 MILLION FOR GRADUATE EDUCATION Provost Tom Sullivan has awarded CBS $920,000 in recurring funds to support graduate programs affiliated with the college’s four departments. Funds will be used to pay teaching assistant salaries, increase stipends for some graduate programs to 4 COLLEGE OF BIOLOGICAL SCIENCES make them more competitive and provide fellowship funds for foreign students. This complements investments made by the state and University to recruit new faculty and build new research facilities. Graduate students, who work in faculty labs and assist faculty in carrying out their research, are a key component of the research enterprise, says Dean Robert Elde. “We are very grateful to the University for this support.” “Driven to Discover” SPOTLIGHTS CBS FACULTY D avid Tilman, Regents Professor of Ecology, and Daniel Bond, assistant professor in the BioTechnology Institute, were among several faculty selected to launch the University’s new marketing campaign, “Driven to Discover.” The campaign, which invites Minnesotans to submit their single greatest question, is designed to strengthen public appreciation of the University’s role as a research institution. Tilman addressed the question “Can we end our dependence on foreign oil?” and Bond replied to “What’s the next alternative energy source?” Their answers were featured in print ads and TV commercials. Go to www.discover.umn.edu for their responses. Daniel Bond, BioTechnology Institute, believes bacteria that transform mud into electricity are a promising source of renewable energy. He was featured in a recent TV commercial. TAKE A WALK DOWN MEMORY LANE CBS luminaries on the Wall of Discovery include botanist Alexander Anderson, who in the 1890s invented the process for puffed cereal; botanist Josephine Tilden, who studied algae in the early 1900s; Nobel Laureates Paul Boyer (biochemistry) and Ed Lewis (genetics); Raymond Lindeman, who discovered how energy moves through an ecosystem; Eville Gorham, who described acid rain; and Gary Nelsestuen, who in 1974 identified proteins that promote and inhibit blood coagulation. Gary Nelsestuen at his spot on the Wall of Discovery. Nelsestuen was recognized for his discovery of proteins involved in blood clotting, which are being used to treat clotting disorders. T he new Scholars Walk, which stretches from Walnut Street near the McNamara Alumni Center west to Appleby Hall and Pleasant Street, and the Wall of Discovery, on the north side of the Electrical Engineering and Computer Science Building, include some familiar names. These tributes to major research and classroom accomplishments by University faculty and students highlight a number of CBS faculty and alumni. The Scholars Walk includes CBS faculty and alumni who have been recognized by the National Academy of Science, the American Academy of Arts and Sciences, as Regents Professors, McKnight Professors, Distinguished Teachers, and Rhodes, Marshall and Truman scholars. BIO ❚ WINTER 2006-07 5 I E L D N O T E S TIM RUMMELHOFF F Sarah Hobbie studies the role of decomposition in nutrient recycling and global climate change. The rotten truth IN A CHANGING WORLD, DECOMPOSITION IS A HOT TOPIC W HAT HAPPENS TO LIVING THINGS WHEN THEY’RE NO LONGER ALIVE MAY SEEM A RATHER AFTER-THE-FACT MATTER FOR A BIOLOGIST. BUT Sarah Hobbie KNOWS OTHERWISE. ASSOCIATE PROFESSOR IN THE DEPARTMENT OF ECOLOGY, EVOLUTION AND BEHAVIOR (EEB), HOBBIE STUDIES THE ROLE THAT DEGRADATION OF ORGANIC MATTER PLAYS IN THE CYCLES OF CARBON AND NUTRIENTS THAT ULTIMATELY SUSTAIN ALL OF LIFE. “I joke with my classes, it’s hard to go tell your grandparents you work on decomposition,” she says. But once she explains how pertinent it is to everything from growing prize tomatoes to global warming, the laughs subside. Decomposition, she says, is critical to recycling plant nutrients. It’s the main pathway by which carbon dioxide fixed by plants is returned to the atmosphere. And it’s the source of organic matter needed for healthy soil. Hobbie, who EEB head Claudia Neuhauser calls “one of the [department’s] leading researchers” in the field of biogeochemistry, began studying decomposition as a graduate student looking at nutrient cycling on the Arctic tundra. She soon realized that it’s a key—and often neglected— variable linked to human-caused global changes such as increases in atmospheric carbon dioxide and fixed nitrogen. Since then she has led a number of studies aimed at understanding the impacts of decomposition and global change on each other. In one project, Hobbie is looking at nutrient cycling in monoculture stands of 14 tree species 6 COLLEGE OF BIOLOGICAL SCIENCES that were planted in Poland three decades ago. When she started the study, she thought the amount of lignin and nitrogen in the leaf litter, shown that the higher the nitrogen in plant material, the faster it rots. “That suggests that humans increasing the input of nitrogen should speed up the rate,” she says. But when she added nitrogen fertilizer to her “DECOMPOSITION IS CRITICAL TO RECYCLING research plots, decompoPLANT NUTRIENTS. IT’S THE MAIN PATHWAY BY sition accelerated on only a few—and even WHICH CARBON DIOXIDE FIXED BY PLANTS IS slowed on some. RETURNED TO THE ATMOSPHERE.” “I still don’t understand those results,” she says. —Sarah Hobbie Because of the prevalence of fertilizer use, she which affects soil microorganisms’ ability to plans to conduct additional experiments until break it down, would control the decomposition she does. rate. “We found out we were completely wrong,” When all is said and done, Hobbie says, she she says. The wrench in the hypothesis turned out to be nightcrawlers, which prefer leaves with hopes to have “contributed some understanding of the basic ecological response to humanlots of calcium. This same nightcrawler species caused global change.” is now invading Minnesota forests, so the research “helps us understand what’s currently going on in Minnesota,” Hobbie says. Hobbie is also studying decomposition at Cedar Creek Natural History Area. Past research has And, she adds, “It would be nice if that information actually related to societal decisions about global change.” —MARY K. HOFF TIM RUMMELHOFF P L A N T B I O L O G Y Peter Tiffin studies the molecular evolution of plants. Evolving with the climate U N D E R S TA N D I N G H O W P L A N T S E V O LV E C O U L D S U G G E S T W A Y S T O H E L P T H E M A D A P T T O G L O B A L C L I M AT E C H A N G E . A T FIRST GLANCE IT MAY SEEM LIKE A CHARMED LIFE. BUT IN REALITY IT’S NOT ALL THAT EASY BEING A PLANT. Anchored firmly by your roots, you can’t out- corn. By comparing the DNA that codes for “There are suggestions that carbon dioxide run, dodge or hide from organisms that aim to eat you. So instead you develop defenses: tough tissue, toxins, thorns, spines. And what do your nemeses do in turn? Develop ways to outsmart them. defenses such as digestion-inhibiting and antifungal proteins in different populations, he’s been able to gain insights into a variety of evolutionary strategies for staying alive in a world replete with plant-eaters. changes the evolutionary trajectory,” he says. “We hope to test this idea as well as identify chromosomal regions contributing to differences among genotypes’ response to carbon dioxide.” This evolutionary pas de deux holds plenty of intrigue for Peter Tiffin, assistant profes- “We consider Peter Tiffin one of the top young stars in the plant molecular evolution field,” says Peter Snustad, acting head of the Department of Plant Biology. “His work on the evolution of plant defense genes and host-parasite interactions is cutting edge.” sor in the Department of Plant Biology. Tiffin started his scientific career studying plants from the perspective of crop production. But he soon found himself captivated not so much by the organisms themselves, but by the molecular changes in their genes that allow them to endure in and adapt to a changing world. Among the most fascinating genetic characteristics Tiffin has studied so far are those that help plants hold their own against herbivores and other enemies. “I want to understand how biotic interactions shape the evolution of organisms,” Tiffin says. “As far as a strong evolutionary force, being eaten is pretty strong.” Tiffin has been looking at molecular genetic differences in two species of teosinte, a Central American grass that is the ancestor of modern “I WANT TO UNDERSTAND HOW BIOTIC INTERACTIONS SHAPE THE EVOLUTION OF ORGANISMS.” —Peter Tiffin Tiffin is also investigating the genetic implications for genetic variation and selection of increasing atmospheric carbon dioxide. To study that, he planted 6,000 Arabidopsis thaliana plants (the botanical equivalent of white mice) in research plots exposed to higher-than-normal carbon dioxide at the College of Biological Sciences’ Cedar Creek Natural History Area research facility. In another study, Tiffin is looking at the relationship between molecular genetic variation and growth range in Clarkia xantiana, a purplepetaled flower found in the Sierra Nevada of California. “With global climate change, there’s a lot of evidence that species ranges will shift,” he says. Improved understanding of the link between genetics and range, he says, may prove valuable to predicting—and potentially boosting—plants’ ability to adapt to such change. —MARY K. HOFF BIO ❚ WINTER 2006-07 7 8 COLLEGE OF BIOLOGICAL SCIENCES INVESTMENT IN RENEWABLE ENERGY AND BIOFUELS RESEARCH I S Y I E L D I N G G R O U N D B R E A K I N G R E S U LT S W I T H B I G T IMPLICATIONS FOR THE STATE hree years ago, when the Initiative for Renewable Energy and the Environment (IREE) was launched, bio-based fuels hadn’t yet entered the mainstream. Gas prices, the war in Iraq and global warming have since propelled bio-based fuels from the back pages to the headlines. And IREE has become a magnet, attracting experts and advocates from academic, government, business and nonprofit sectors to shape Minnesota’s future in the emerging renewable energy industry. “We’ve built a lot of momentum in just a few years. Now Minnesota needs to make a serious commitment to maintaining a competitive edge in biofuels research and production,” says Robert Elde, dean of the College of Biological Sciences, executive director of IREE and the driving force behind the planned National Center for Biofuels Research at the University of Minnesota. Elde has observed firsthand what can result from collaborative, interdisciplinary research. He played a critical role in bringing together researchers and faculty with expertise in the biological sciences, public policy, economics and technology to form IREE. “We have already moved on to the next generation of biofuels,” says Dick Hemmingsen, IREE’s director. “From alternative crops like mixed prairie grasses and wood pulp as well as algae and microorganisms you can grow in a Petri dish.” One example: A recent discovery by David Tilman, Regents Professor of Ecology, that prairie grass is a more efficient and viable source of biomass for producing biofuel on a large scale. The research is happening, but future investment will determine whether Minnesota stakes its claim as a biofuels hub. ALL ABOUT IREE IREE was launched in 2003 when the Minnesota Legislature directed $20 million in funds, set aside by Xcel Energy for alternative energy development, to the initiative (a $10 million lump sum followed by $2 million a year through 2007). IREE draws on the intellectual resources of six colleges and professional schools including the College of Biological Sciences. Its mission: to promote statewide economic development, sustainable, healthy and diverse ecosystems, and national energy security through development of bio-based and other renewable resources and processes. A big goal, and one IREE is already delivering on. BIO ❚ WINTER 2006-07 9 “WE’VE BEEN ABLE TO COALESCE UNIVERSITY OF MINNESOTA RESEARCHERS INTO A REAL FORCE.” —Robert Elde Robert Elde, Executive Director of IREE In three years, IREE has evolved from an idea to a hub for renewable energy—especially biofuels—research in the region. The initiative has funded 110 renewable energy projects involving more than 275 faculty, research scientists and students at the University of Minnesota. Biofuel projects go way beyond headline-grabbing crop-based ethanol to cuttingedge inquiry into the potential for hydrogen, wind power and even bacteria to produce energy efficiently and cost-effectively. Despite the progress made, Hemmingsen’s optimistic outlook is tempered by a sense of urgency about maintaining a foothold in the fastmoving world of biofuels development. “We’ve done a good job starting out, but we’re already in danger of falling behind,” he says, pointing to proposals in other states—not to mention tremendous investments in other countries—as an indication of what Minnesota and the University are up against in keeping ahead of the curve. “Many states are committing much more,” adds Elde, “and the reality is that we are competing with them to establish our niche in the renewable energy economy.” RIGHT HERE, RIGHT NOW Ethanol is a billion-dollar business in Minnesota, literally. The BioBusiness Alliance of Minnesota’s 2006 Statewide Biobusiness Assessment notes that Minnesota is the second largest producer of ethanol in the country with an annual production value approaching an estimated $1 billion. The state’s leadership in biofuels makes sense for a variety of reasons. For one, there’s a unique convergence of an agriculture base matched with a strong biobusiness sector. State support is also strong. “The state has embraced biotechnology and research in renewable energy with its policy,” points out Darren McBeth, executive director of the Minnesota Agri-Growth Council. “There are more ethanol plants in Minnesota than almost anywhere else. Minnesota was the first state to mandate 10 percent [ethanol content in gasoline], which then doubled to 20 percent two years ago, and it’s the first state to mandate 2 percent for biodiesel.” Those policies have set the stage for the growing demand for better, more cost-effective biofuels such as cellulosic ethanol. The rising price USING ALGAE TO MAKE HYDROGEN FUEL Hydrogen is all around us, but it’s almost always bound to other elements. Isolating hydrogen for emission-free, renewable fuel is challenging. Paul Lefebvre and Carolyn Silflow, Department of Plant Biology, are collaborating with Michael Flickinger at the BioTechnology Institute to amplify the capacity of Chlamydomonas reinhardtii, a one-celled algae, to produce hydrogen. They received a $405,000 grant from IREE to carry out the research. 10 COLLEGE OF BIOLOGICAL SCIENCES PUTTING CARBON IN ITS PLACE BIONIC PLASTIC Wetlands store carbon, which keeps it from entering the atmosphere and adding to global warming. James Cotner and Shinya Sugita, Department of Ecology, Evolution and Behavior, are exploring how this process works in order to identify ways to manage wetlands to maximize carbon storage. They are also analyzing sediment to learn how human impact has altered this system over the past few hundred years. Their research is funded by a $333,000 grant from IREE. Bio-based plastics may be more than a replacement for oil-based plastics because they can be engineered to provide useful functions. Romas Kazlauskas and Claudia SchmidtDannert, Department of Biochemistry, Molecular Biology and Biophysics, and the BioTechnology Institute’s Friedrich Srienc are developing a polymer that conducts electricity and can be used in electronic devices. IREE awarded the team a $405,000 grant to support this research. and inevitable decline in supply of fossil fuels coupled with the limitations of corn- and grain-based ethanol, which compete with food production, has spurred innovation. And IREE has taken the ball and run with it by funding cutting-edge research and creating a vital bridge between academia and the business community. So far, IREE has collaborated with more than 40 business and industry partners, 12 universities and higher education institutions, and an additional 50-plus outside organizations including state and federal agencies and departments, national laboratories, trade organizations, foundations and non-governmental organizations. “Minnesota is unique because it has got the best of both worlds—urban and rural,” McBeth points out. That balance of agricultural resources and technical and business capability puts the state at an advantage over other states that lean more heavily toward one or the other. In other words, Minnesota has the benefit of both biomass and biotech. Fresh Energy’s Michael Noble makes the case that Minnesota should use those advantages aggressively to stake a claim to alternative energy. “Minnesota should be as ferociously devoted to promoting energy efficiency and technology as Alaska is to exporting oil or Oklahoma is to the natural gas industry.” EARLY RETURNS “You need to have people like [University of Minnesota’s] David Tilman, Lanny Schmidt and Ken Keller having these discussions,” says Edward Garvey, deputy commissioner for energy and telecommunications at the Minnesota Department of Commerce and an early supporter of IREE. “You need these folks [from diverse disciplines] to be in the game cross-pollinating each other. And that’s what IREE is starting to do.” In recent years, similar undertakings have sprouted up at universities across the country. “The difference with this initiative is just how comprehensive it is. … Integrating policy, economics and ecosystems research is unique to IREE,” says Hemmingsen. So in addition to biofuels research, IREE provides a framework for analysis. This is key, Hemmingsen notes, since inventions or new discoveries should be coupled with an understanding of costs involved in bringing them to market, the policies needed to make their use widespread and an understanding of the environmental impacts. IREE brings together faculty and researchers from across disciplines as different as biochemistry and public policy to make that happen. “We’ve been able to coalesce this group into a real force,” adds Elde, “which is something that advances the University’s leadership in this area.” Some of the early returns on that $20 million investment include: ❚ The first large-scale wind turbine at a public university in the country at the West Central Research and Outreach Center near the University of Minnesota’s Morris campus; ❚ research on ways of making hydrogen from biological materials such as Lanny Schmidt's development of a reactor that converts ethanol to hydrogen. ❚ development of an innovative biomass gasification system, and; ❚ the potential to produce a type of nitrogen fertilizer from wind power. BIO ❚ WINTER 2006-07 11 “THE EASIEST MISTAKE WE COULD MAKE WOULD BE A FAILURE TO THINK BIG… THE BIGGEST MISTAKE WOULD BE TO UNDER-INVEST.” —Michael Noble Fresh Energy’s Michael Noble IREE research has even resulted in the launch of a biotech start-up based on a process developed by Larry Wackett, head of microbial chemistry, which uses bacteria to transform common renewable resources into fuel hydrocarbons. Progress has been made on the economics and policy fronts, too. Stephen Polasky, who specializes in applied economics, and David Tilman developed a full-cost accounting of energy use to objectively compare the costs of renewable and conventional energy sources; an important step toward making renewable energy sources competitive. Elde wants to take biofuels research to the next level by establishing the National Biofuels Research Center (NCBR) to capture and feed the momentum created so far by IREE. The NCBR would bring together everything needed to conduct cutting-edge biofuels research, teaching and technology development in a single facility on the St. Paul campus. The idea to create a hub for biofuels research at the University of Minnesota follows logically on IREE’s record of innovation. “Taking bold steps will move the University and Minnesota closer to realizing our goal of being a leader in biofuel production,” Elde says. “The University and the state are depending on us for leadership in areas that are critically THE COMPETITION HEATS UP important to the future of Minnesota and the planet.” In laying out the University’s budget request for 2008-09, University of Minnesota President Robert Bruininks articulated the return on invest- JUST GETTING STARTED ment possible with some forward thinking. “From renewable energy to Ultimately, says Hemmingsen, biofuels research isn’t optional. It’s a the biosciences, these are critical investments in Minnesota’s future. necessity; a national and global imperative. “We have to do it,” he says. Tomorrow’s jobs are being invented today by our researchers, faculty and “We have no choice.” students,” says Bruininks. “This plan is not just about holding our own— it’s about gaining ground in an increasingly competitive world.” The BioBusiness Alliance report emphasizes just how seriously the state needs to take that competition: “Minnesota has no grounds for being complacent regarding its future position in research and development within the life sciences.” Fresh Energy’s Noble concurs. Noble agrees. “The easiest mistake we could make would be a failure to think big, to not realize that energy issues are at the root of our global security issues,” he says. “Energy issues are at the root of economic prosperity. And energy issues are at the root of our global environmental problems. The biggest mistake would be to under-invest.” Noble adds that the potential for Minnesota to remain competitive is very real, even with more and more intense competition. “There’s no reason why Minnesota and its neighboring states can’t be the nation’s top producer of cellulosic biofuels, wind energy, even hydrogen and solar electricity,” he says. “But the idea that it’s going to fall in “Minnesota has a reputation as a national leader [in biofuels], but I think there’s so much more we could do,” he says. “It’s easy to be proud of our accomplishments but it’s more important to challenge ourselves to do better.” But funding is critical. “We’re starting to see a lot of really big companies investing significant money at universities,” notes Hemmingsen. Two recent examples: a $12 million research partnership between Chevron and the Georgia Institute of Technology launched earlier this year and a $500 million grant to be awarded by BP to a single university in early 2007. our laps is false.” State funding is also on the rise. Michigan is proposing $200 million and California $1 billion for renewable energy research at their respective university systems. “Minnesota hasn’t made that kind of commitment yet,” notes Hemmingsen. To make good on IREE’s mission and, at the same time, advance Minnesota’s standing as a leader in biofuels research will require an ongoing investment. 12 COLLEGE OF BIOLOGICAL SCIENCES And the most direct path to keeping that edge starts with ensuring ongoing support at the state and federal level for IREE and NCBR. “The University has repeatedly proven its ability to develop new ideas and new technologies that enable Minnesotans to be better off,” notes Sen. Steve Kelley, another critical early supporter of IREE. “Given that track record, [investing in IREE] is the right thing to do.” State Senator Steve Kelley —STEPHANIE XENOS G E N E T I C S Yeast raises good questions Y EAST—FROM THE KIND USED IN BEER AND BREAD TO THE KIND THAT CAUSES DEADLY INFECTIONS—HAS PROVIDED YEARS OF INTERESTING QUESTIONS FOR ONE RESEARCHER. a flat surface of silicon or glass, Berman has discovered that when exposed to antifungal who clings to a single focus of study for an drugs, C. albicans pulls the amazing trick of entire career. “Biology is so wide open a field— modifying one of its chromosomes. It copies that’s what appeals to me,” says the professor one arm of chromosome 5 so that it can carry of genetics, cell biology and development. “My two copies of this chromosome arm on a strength is in having a broad understanding of new, rearranged chromosome. The altered yeasts. And I like to use chromosome is called that strength to find an isochromosome. interesting questions.” BERMAN RECENTLY DISCOVShe is currently harBerman and her nessing her expertise ERED THAT C. ALBICANS research team pubin yeasts—singlelished an article in a ALTERS A CHROMOSOME TO celled fungi—to explore recent issue of the several pioneering journal Science RESIST ANTI-FUNGAL DRUGS. paths of research. describing this THE FINDING COULD LEAD TO discovery. “This major One of her avenues of genome rearrangeBETTER TREATMENTS. investigation spotlights ment occurs in 20 perCandida albicans, a cent of the Candida yeast that can cause albicans strains that infections in humans. In healthy people, this become resistant to antifungal drugs,” she yeast often exists harmlessly in the mouth and says. Her findings suggest that pairing antigastrointestinal tract. Sometimes it produces fungal treatment with a companion drug that troublesome oral or vaginal infections. But in blocks the genetic rearrangement offers people with a weakened immune system, such hope for extending the usefulness of the curas those who have AIDS or have undergone rently available antifungal drugs. Her next chemotherapy, these infections can blossom step: “We’re now trying to understand the into life-threatening episodes. Berman’s mechanism of how the extra chromosome arm research focuses on a consequence of medical is gained and lost,” she says. treatment intended to control serious infections of C. albicans: the organism’s unusual method Berman began her study of yeasts years ago of developing resistance to drugs. with research on a more prosaic organism, Because many agents toxic to yeasts are also toxic to humans, most yeast-fighting drugs have been designed to control the growth of yeast populations rather than wipe them out. Using microarrays, segments of DNA affixed to Saccharomyces cerevisiae, which is responsible for the rising of bread and the fermentation of beer. She has not abandoned her old laboratory companion. For the past two years, she has collaborated with a researcher at the Weizmann TIM RUMMELHOFF Judith Berman is not the kind of scientist Judith Berman studies several varieties of yeast, a one-celled fungi that provides insights into human genetics. Institute of Science in Israel in a comparison of the ways in which S. cerevisiae and C. albicans convert their DNA sequence into cellular functions. This process is called gene expression. “We’re interested in finding out how patterns of controlling genes have evolved over time,” Berman says. Another question, another course of research. —JACK EL-HAI BIO ❚ WINTER 2006-07 13 B I O L O G Y TIM RUMMELHOFF S T R U C T U R A L Crystal clear STRUCTURAL BIOLOGIST CARRIE WILMOT USES X-RAY CRYSTALLOGRAPHY TO “SEE” THE STRUCTURE OF PROTEINS THAT AFFECT HUMAN HEALTH T HE WORLD OF STRUCTURAL BIOLOGY HAS BEEN BETTER OFF SINCE Veterinary medicine was an early career choice for Wilmot, assistant professor in the Department of Biochemistry, Molecular Biology and Biophysics. “Then I became allergic to cats and dogs,” she says. Instead of treating animals, Wilmot transferred her interests to crystallography—the technique of determining the 3D structural arrangement of molecules by hitting crystalline samples with a beam of X-rays and studying the patterns of diffraction that result. Because of her expertise in crystallography and spectroscopy, the U.K.native has gained wide recognition as an authority in the difficult task of successfully preparing samples of protein enzymes for analysis. “She’s world-famous for developing the techniques to catch enzymes in their different structural states as they go through the steps of their enzymatic reactions, and to trap them in a crystal so she can determine the structure,” says David Thomas, who heads the structural biology group. Wilmot has focused her attention on several protein enzymes in particular. One, copper-containing amine oxidase, is implicated in such human health problems as congestive heart disease and inflammatory diseases, such as rheumatoid arthritis. When present in the blood, the enzyme 14 COLLEGE OF BIOLOGICAL SCIENCES Carrie Wilmot DECIDED NOT TO BECOME A VET. can produce inflammation by drawing into sursoluble form of a protein fragment is largely rounding tissues the cells that help fight off responsible for memory loss in Alzheimer’s pathogens. The enzyme also produces formaldedementia. Ashe has succeeded in purifying this hyde and hydrogen peroxide, chemicals that can protein assembly, and Wilmot is going to solve damage hearts already weakened by cardiac disits structure to understand why this particular ease or diabetes. form of the protein has “Here is a single such devastating effects in enzyme that reprehumans. “Carrie does very “WE’RE TRYING TO PROVIDE A sents a key step in the well researching in collabPLATFORM OF KNOWLEDGE FOR inflammatory oration with other investiresponse,” Wilmot gators,” Thomas says. “Her PEOPLE WHO WANT TO DESIGN says. contribution is valuable DRUGS AIMED AT ENZYMES.” because she’s a world And because the expert in determining proenzyme acts alone, —Carrie Wilmot tein structures.” Wilmot has found it an attractive target for This year the American investigation. Her hope is that examination of the Crystallographic Association gave Wilmot its enzyme’s structure will suggest pharmaceutical Margaret C. Etter Early Career Award, and she approaches to inhibiting its effects. “What we’re earlier received the Paul D. Saltman Memorial trying to do is to provide a platform of knowledge Award from the Gordon Research Conferences. for people who want to go on and design drugs “I’m motivated by the beauty of protein strucaimed at the enzyme,” she says. tures,” she says. “I’ve been doing this for over a Also in her investigative sights are various decade, but I still get such a thrill the first time I molecular assemblies connected to Alzheimer’s look at one. They provide the answers to so many disease. In this research she collaborates with questions, and open up so many more.” Karen Ashe, professor of neurology and neuro—JACK EL-HAI science, who has discovered that a particular S T U D E N T L I F E Refugee camp TO MEDICAL SCHOOL N A KENYAN REFUGEE CAMP, MOHAMED ABDIHALIM DIDN’T HAVE TO WORRY ABOUT THE WAR IN SOMALIA, SO HE COULD CONCENTRATE ON SCHOOL. they moved again, just across the Kenyan bor- being asked, ‘What tribe are you from?’ by a gunman. If you’re from the wrong tribe, in the wrong city, you would get robbed or killed. Tribe was everything.” der. “After the first two years, even that place An aunt brought Abdihalim to the United Mohamed Abdihalim was nine when he and his family fled their home in Mogadishu, Somalia because of civil war. Months later, became too dangerous, because the militia would make “THE DOCTORS TREATED States. After graduating from high school in Minneapolis, he attend- raids,” Abdihalim recalls. “It was a PEOPLE NO MATTER WHAT ing in biochemistry. He scary time.” So the family moved again, TRIBE THEY BELONGED TO— graduated from CBS to a United Nations THEY DIDN’T EVEN ASK. FOR A summa cum laude in the spring of 2005 and started at the University refugee camp deeper inside Kenya. Abdihalim came to ed the University, major- SOMALI TEENAGER, IT WAS AN of Minnesota Medical EYE-OPENING EXPERIENCE.” Minnesota in 1999, at —Mohamed 17. Despite spending almost half his childhood in refugee camps, he says, “I consider myself lucky.” In the camp, Abdihalim explains, “I didn’t have to worry about the war. I could concentrate on school.” At school—a tent without chairs, tables or electricity—he learned among other things to speak English. For a time, the camp had one hospital and one physician. When physicians from the organization Doctors Without Borders arrived, the Somali doctor suggested that Abdihalim work as a translator. The doctors treated people no matter what tribe they belonged to—they didn’t even ask. For a Somali teenager, it was, Abdihalim recalls, “an eye-opening experience.” The contrast to Somalia was striking. “The war [in Somalia] is a tribal war, Abdihalim says. “What got me to the camp was tribal warfare. You could not walk in a Somali city without Abdihalim School in fall 2005. Soon afterwards, Abdihalim became the first University of Minnesota student ever awarded a scholarship from the Jack Kent Cooke Foundation, which was started by the real estate, media and sports mogul, who died in 1997. A high school dropout, Cooke once described himself as an “indomitable optimist.” TIM RUMMELHOFF I Competition for the scholarships is intense. More than 1,200 individuals from across the United States applied for graduate school assistance last year, with about 75 receiving awards of as much as $50,000 annually. For Abdihalim, who has another small scholarship, that amounts to about $40,000 per year. Abdihalim just started his second year of medical school, after a summer of helping a researcher at the Mayo Clinic. His dream is to spend several months of each year working in Somalia. He is still inspired by the physician who first took an interest in him more than a When he completes his medical education, Mohamed Abdihalim hopes to practice in the United States and Somalia. decade ago, and started him working as a medical translator. “I feel this sense of responsibility, to patients and to my community,” Abdihalim says, “to give back.” —FRANK CLANCY BIO ❚ WINTER 2006-07 15 G I V I N G B A C K What matters to you? MAKING YOUR GIFT MEANINGFUL ❚ The new Science and Interpretive Center at Cedar Creek Natural History Area ❚ The planned National Center for Biofuels Research ❚ Habitat for Biologists or the planned Campus Center at Itasca Biological Station and Laboratories ❚ Graduate fellowships to support “YOU SHOULD FEEL AS GOOD ABOUT YOUR GIFT AS THE RECIPIENT DOES.” —Laurie Hennen undergraduate students who conduct research in molecular biology. the Norwegian Centennial Laurie Hennen, CBS director of development, works with donors to help them identify giving opportunities that suit their personal needs and interests. Interdisciplinary Chair in Biofuels DAVID GRANTHAM BURBEE and Food Safety MEMORIAL SCHOLARSHIP ❚ Scholarships and fellowships Dr. Clark Burbee made a gift of $25,000 to honor the memory of his son, David Grantham Burbee (B.S. biochemistry, 1977). David continued his education at Cornell University and went on to a career in biochemistry and genetics. He attributed the development of his interests to faculty and friends at the University of Minnesota. David Burbee passed away in October 2005. Clark Burbee’s gift has been matched by the President’s Scholarship Fund. for deserving students in all areas of biology I DON’T FOCUS ON RAISING MONEY AS DEVELOPMENT DIRECTOR FOR THE COLLEGE OF BIOLOGICAL SCIENCES. I focus on helping friends of the college identify opportunities that match their needs and interests. To do that, I need to get to know them so that I can point to the options— big or small—that are best. This is the most enjoyable part of my job. You may be thinking about giving to a scholarship, research or educational program, buildings or all of the above. You may be reflecting on how you benefited from someone else’s generosity, the impact of a professor on your life, or research that is particularly meaningful to you. For every interest or inclination, there is a need you can help fill. Here are some of the ways that you can give back to the College of Biological Sciences. 16 COLLEGE OF BIOLOGICAL SCIENCES Please send an e-mail or give me a call if you would like to learn more about any of these opportunities. I look forward to meeting you, learning about your connection to CBS and telling you about the important work that’s going on here. Contact me at [email protected] or 612-624-9460. Here are some examples of recent scholarship gifts. Each comes with a unique personal story. JULIAMARIE ANDREEN GRILLY SCHOLARSHIP Juliamarie Andreen Grilly earned a B.S. in bacteriology from the University of Minnesota in 1946. She worked her entire professional career as a research scientist at Los Alamos National Laboratory. She was also an accomplished cellist and golfer. After Juliamarie died in November 2005, her husband, Edward Grilly, established this scholarship in her memory with a gift of $150,000. The gift supports WALLACE ARMSTRONG/ VENKATESWARLU POTHAPRAGADA GRADUATE FELLOWSHIP This fellowship honors Walllace Armstrong, a biochemistry faculty member from 1934-74, who discovered the protective effects of fluoride. It was created with a $25,000 gift from Venkateswarlu Pothapragada (Ph.D. physiological chemistry, 1962) and his employer, 3M. The gift has been matched by the University of Minnesota 21st Century Graduate Fellowship Endowment. Preference will be given to applicants who have a connection to or strong interest in India. —LAURIE HENNEN A L U M N I Calendar N E W S Class notes BEHIND THE SCENES TOUR OF THE SCIENCE MUSEUM’S EXHIBIT ON RACE January 20, 2007 | 5:30-8 p.m. Enjoy a private reception and an exclusive after-hours tour of the Science Museum’s exhibit, RACE, with Dean Robert Elde. RACE combines human experience, history and science to explore the concept of race and its role in our world. www.smm.org DEAN’S BOOK CLUB Matthew P. Finke (B.S. Biochemistry, 1997). After graduating from CBS, Matthew completed a Master of Public Health (MPH) degree at the University of Minnesota in 2000 and earned his M.D. degree at the University of South Dakota School of Medicine in 2006. While in medical school he initiated Public Health Week in South Dakota, for which he received the South Dakota State Medical Association’s Past Presidents’ Leadership award. He began a residency in emergency medicine at University of Iowa Hospitals and Clinics in July. Minali Gala (B.S. Genetics, Cell Biology and February 22, 2007 | 6-8 p.m. Enjoy hors d’oeuvres and discussion about Michael Pollan’s best-selling book Omnivore’s Dilemma, which explores connections between food, energy and the environment. www.michaelpollan.com VANCOUVER ISLAND STUDY TOUR June 2007 Spend five days exploring Vancouver Island in British Columbia with Dean Elde and fellow alumni from the College of Biological Sciences. Learn about Seaside Station, a UM field study outpost established by botany professor Josephine Tilden at Botanical Beach in the early 1900s. Vancouver Island offers pristine coastlines and an abundance of flora and fauna. www.vancouverisland.travel Space at these events is limited. Please contact Jean Marie Lindquist at [email protected] or 612-625-7705 for more information. Making Connections Bill Diekman (B.S. Biology, 1987) is 2006-07 president of the Biological Sciences Alumni Society. Under his leadership, the board is working to build relationships with alumni, raise money for the college, and support Dean Elde's research and education goals. BSAS activities include the Mentor Program, which matches undergraduates with alumni working in careers they plan to pursue; the Dean's Book Club; and the Vancouver Island Study tour. www.cbs.umn.edu Click on Alumni & Friends Development, 2005). Minali has been working at PDL Biopharma, Inc., where she had previously done an internship, since July 2005. She hopes to go back to school to get an MBA in the near future. A native of India, she returns home once a year to spend time with her family. Imee Cambronero (B.S. Biology, 2003). Imee has held several different positions in the Minnesota and Washington, D.C. offices of Congresswoman Betty McCollum since graduation. She maintains her Minnesota connections through involvement with the Philippine Center of Minnesota Board, the University of Minnesota Alumni Association and the CBS Alumni Board of Directors. Karen Dallas (B.S. Microbiology, 2001). Karen received her M.D. degree from McGill University in Montreal, Quebec. She is completing a residency in hematopathology at the University of Toronto. Paul A. Rebers (Ph.D. Biochemistry, 1953) died on May 31 at the age of 83. A retired chemist at the National Animal Disease Center in Ames, Iowa, Rebers’ research focused on lipopolysaccharide antigens found in Pastuerella multocida, which is responsible for fowl cholera. He co-edited the book Radon, Radium and Uranium in Drinking Water, which was published in 1990. Rebers was preceded in death by his son Joseph, and is survived by his wife, E. Louise, two sons and two grandchildren. Joe Novak (Ph.D, Science Education and Biology, 1958) recently received an honorary doctorate and a gold medal from the University of Urbino for contributions to science education. Joe also has received honorary doctorates from the Universidad Publica de Navarra, Pamplona, Spain and the Universidad Nacional del Comahue, Neuquen, Argentina. Julie Constable (Ph.D Ecology, Evolution and Behavior, 2000) has been living in Fresno, California for the better part of four years. She is a part-time lecturer in the biology department at California State University (CSU), Fresno, as well as an adjunct faculty member at CSU Stanislaus. Julie is also employed fulltime as a wildlife ecologist by the Endangered Species Recovery Program, studying the endangered San Joaquin Kit Fox in the Central Valley of California. Please take a couple minutes to update us about your career and personal life. Let your fellow alumni know about your new job, awards, publications, current research, family changes and travel experiences. E-mail to [email protected]. BIO ❚ WINTER 2006-07 17 D O N O R H O N O R R O L L Donor honor roll EVERY GIFT MAKES A DIFFERENCE T HE COLLEGE OF BIOLOGICAL SCIENCES GRATEFULLY ACKNOWLEDGES THE FOLLOWING DONORS, WHO HAVE GENEROUSLY PROVIDED SUPPORT FOR STUDENT SCHOLARSHIPS AND FELLOWSHIPS, RESEARCH AND A VARIETY OF SPECIAL INITIATIVES DURING FISCAL YEAR 2005-06. EVERY GIFT MAKES A DIFFERENCE. IF YOUR NAME IS MISSING OR LISTED INCORRECTLY, PLEASE CALL 612-625-7705 OR E-MAIL [email protected]. $5,000+ $1,000 – $4,999 3M Company 3M Foundation Inc. Athena Diagnostics Inc. C. Robert Binger M John G. Brittingham Clark R. Burbee M Jonathan C. Burbee Care for the Wild International Cargill Inc. The Cleveland Foundation Edward J. and Carolyn Cushing E I Du Pont De Nemours & Co. T. Dan and Debra Friedkin Thomas H. Friedkin General Mills Inc. Loren L. Bahls M Carl V. Barnes Judith G. Berman Marcia F. Birney Joanne J. Brooks Robert J. Buck and Cheryl L. Quinn M Richard S. and Lucille P. Caldecott M Cortec Corporation Douglas and Wendy Dayton Denneth C. and Joan L. Dvergsten M Robert P. Elde Leroy W. Gardner M Charles M. Goethe Estate Margherita Gale Harris John J. Jackson III Jane E. Johnson Johnson & Johnson Kaufman Family Foundation Carol F. Kirkwood Erika E. Lauffer and Max A. Lauffer Jr. M Mary E. and David W. Loveless John S. and Theresa R. Mc Keon Meadowood Foundation J. Emory Morris Claudia M. Neuhauser Kien T. Nguyen and Julie A. Warren Jean M. Parmelee M John F. and Mary F. Pelton The Pfizer Foundation Bernard O. and Jean S. Phinney M James R. and Patricia M. Pray M Kipling Thacker and Kevyn K. Riley M Jeffrey A. Simon and Ann E. Rougvie Patricia B. and James B. Swan M G. David and Catherine E. Tilman Nancy Wilson The Windibrow Foundation Robin L. Wright M Shye-Ren Yeh M Freshman at Nature of Life E. R. Grilly Harris Rebar Stan T. Jensen Mary C. Kemen and Brian C. Randall M Legendary Adventures Inc. Lincoln Park Zoological Society Metabolix Inc. National Ataxia Foundation John G. Ordway Jr. M Nora S. Plesofsky Richard E. and Meredith B. Poppele Venkateswarlu Pothapragada M Clare and Jerome Ritter Elizabeth Burbee Seaton Jocelyn E. Shaw $500 – $999 Advanced Telemetry Systems Inc. Patrick J. and Ann W. Antonelli David and Suzanne Bernlohr Boston Scientific Corporation Eric W. Burton Cargill Foundation John E. and Ting L. Carlson Con Edison M membership in the University of Minnesota Alumni Association/Biological Sciences Alumni Society 18 COLLEGE OF BIOLOGICAL SCIENCES Timothy J. and Rita A. Ebner David R. Edwards Maxine A. Enfield M Guidant Corporation Nancy and Robert J. Haight M Roy H. and Susan A. Hammerstedt Thomas R. Jacques James C. Underhill Scholarship-Study Natural History Fund Sandra L. Johnson M Martha K. and Arthur A. Johnson Patricia R. Lewis Pamela H. Lewis Nancy G. Lillehei May So-Ying and Alec Y. Lui M David J. and Esther G. Mc Laughlin Medtronic Inc. Haile Mehansho M Dan and Mical Middaugh M Monsanto Fund Gary L. and Mary Nelsestuen M Mary H. Nett M Corbett M. Peterson The Pharmacia Foundation Inc. William and Margaret Pilacinski Carol H. and Wayne A. Pletcher M Russell J. and Nina M. Rothman M Gloria T. and Orlando R. Ruschmeyer M Penny and Robert S. Sikes Jr. Smiths Medical MD Inc. St. Jude Medical Inc. Clifford J. Steer M SurModics Inc. Ruth R. Thiel Louise and Ben Thoma M Steven J. Thompson Katherine M. Walstrom Agnes M. Walz $250 – $499 Jeffrey J. Anderson John S. and Rebecca H. Anderson M Robert A. Arntsen Charles Barthold Allan Baumgarten and Marilyn LeviBaumgarten M W. David Benton Daniel D. Billadeau Ross A. Bjella M David E. Blockstein John E. and Terri L.Brandt * deceased 2006 graduate Vera E. Cooke Robert R. and Barbara L. De La Vega M Gary L. Dillehay M Mark S. and Patricia J. Ellinger M Daniel R. Engstrom and Barbara A. Coffin James M. Fitzpatrick M William R. Fraser M Jeffrey D. Gabe GlaxoSmithKline Foundation James P. Grover Kathryn L. Hanna M David A. Hanych M Paul E. Huepenbecker M George L. Jacobson Thorkil Jensen Patti Jo Jukich Andrew R. and Mary Ellen Klemer Betty V. and James F. Koerner L E Phillips Family Foundation Judith L. Maccanelli The Medtronic Foundation Cheryl L. and George G. I. Moore Bradly J. and Terry L. Narr M Richard E. and Elaine E. Phillips Sandra K. Rosenberg and James E. 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Woolard Judith L. Wulff Brent L. Wyrick Zhaohui Xu James J. Youngblom Jeffrey Y. Yung M BOLD Membership in University of Minnesota President’s Club BIO ❚ WINTER 2006-07 21 Nonprofit Org. U.S. Postage PAID Mpls., MN. Permit No. 155 123 Snyder Hall 1475 Gortner Avenue St. Paul, MN 55108 B I O F U E L S Prairie grass biofuel is the best choice FO R T H E E C O N O M Y A N D T H E E N V I R O N M E N T H IGH-DIVERSITY MIXTURES OF NATIVE PRAIRIE PLANT SPECIES HAVE EMERGED AS THE LEADER IN THE QUEST TO IDENTIFY THE BEST SOURCE OF BIOMASS FOR PRODUCING SUSTAINABLE, BIO-BASED FUEL TO REPLACE PETROLEUM. A new study led by David Tilman, Regents Professor of Ecology in the University of Minnesota’s College of Biological Sciences, shows that mixtures of native perennial grasses and other flowering plants provide more usable energy Tilman and two colleagues, postdoctoral researcher Jason Hill and research associate Clarence Lehman, estimate that fuel made from prairie biomass would yield 51 percent more energy per acre than per acre than corn-grain ethanol or soybean biodiesel, and are far better for the environment. ethanol from corn grown on fertile land. This is because prairie plants, which are perennials, require little energy to grow “Biofuels made from diverse mixtures of prairie and all parts of the plant above ground plants can reduce global warming by removing carbon dioxide from the atmosphere, meet a substantial portion of global energy needs, and leave fertile land for food production,” Tilman said. are usable. The findings were published in the Dec. 8 issue of the journal Science and featured on the cover. Based on 10 years of research at Cedar Creek Natural History Area, the study shows that land planted with highly diverse mixtures of prairie grasses and other flowering plants produces more than twice the amount of bioenergy than the same land planted with any single prairie plant species, including switchgrass. Research plots at Cedar Creek Natural History Area were used to study the potential of native prairie plants as a source of bio-based fuel. Fuels made from prairie biomass are “carbon negative,” which means that they reduce the amount of carbon dioxide (a greenhouse gas) in the atmosphere. This is because perennials store more carbon dioxide in roots and soil than is released when fuels made from them are burned. Using prairie biomass to make fuel would remove and store from 1.2 to 1.8 U.S. tons of carbon dioxide per acre per year. In contrast, corn ethanol and soybean biodiesel are “carbon positive,”meaning they add carbon dioxide to the atmosphere, although less than fossil fuels. The researchers estimate that growing mixed prairie grasses on all of the world’s degraded land could produce enough bioenergy to replace 13 percent of global petroleum consumption and 19 percent of global electricity consumption. The research was supported by the University of Minnesota Initiative for Renewable Energy and the Environment and by the National Science Foundation (NSF). Cedar Creek Natural History Area has been an NSF Long-Term Ecological Research (www.lter.umn.edu) since 1982.