CURRICULUM VITAE
Transcription
CURRICULUM VITAE
Chow L.W.C. CURRI CULUM VIT A E PERSONAL PARTICULARS NAME: SEX: Louis Wing-Cheong CHOW Male QUALIFICATIONS Basic Qualification: Postgraduate Qualifications: M.B.B.S. (HK) F.R.C.S. (Glasgow) F.C.S. (HK) F.H.K.A.M.(Surgery) M.S. (HKU) F.A.C.S. May 1984 May 1988 December 1990 December 1993 December 1999 October 2004 SABBATICAL TRAINING Breast Service Jul – Nov 1994 Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA Division of Surgical Oncology Jan 1993 Department of Surgery, University of Southern California, Los Angeles, USA Division of Surgical Oncology Oct – Dec 1992 Department of Surgery, Yale University, USA Gastric & Mixed Tumors Service Jul – Sep 1992 Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA PRESENT APPOINTMENTS Visiting Professor Oct 2008 – present Wuhan University of Science and Technology P.R. China Honorary Consultant Feb 2008 – present Kiang Wu Hospital, Macau SAR Honorary Professor Dec 2007 - present Ningxia Medical College School of Clinical Medicine , Ningxia, P.R. China Medical Director Jan 2006 – present Comprehensive Centre for Breast Diseases UNIMED Medical Institute, Hong Kong SAR Honorary Professor Apr 2004 – present Tohoku University, Sendai, Japan 1 Chow L.W.C. PRESENT APPOINTMENTS IN PROFESSIONAL ASSOCIATIONS Editorial Board Member Sep 2011 – present Breast Case Editorial Board Member Aug 2010 – present Chinese Journal of Clinicians (CJC) Executive Board Member Jun 2010 – present European-Asian Society for Breast Disease (EURAMA) Editorial Board Member May 2010 – present Journal of Angiogenesis Research Editorial Board Member Jan 2010 – present Chinese Journal of Cancer Research Executive Committee Member Oct 2009 – present Chinese Society of Clinical Oncology Deputy Editor-in-Chief Oct 2008 – present Editorial Board, Chinese Journal of Breast Disease (Electronic Edition) Vice-Chairman Oct 2008 – present Breast Group, Oncology Branch, Chinese Medical Association Executive Chief Editor Jul 2007 – present Editorial Board, Chinese Journal of Traditional and Western Medicine Executive Director Dec 2002 – present Organisation for Oncology and Translational Research Executive Member Apr 1999 – present Asian Breast Cancer Society PREVIOUS APPOINTMENTS Honorary Secretary Dec 2008 – 2012 The Hong Kong Academy of Medicine, Hong Kong SAR Honorary Clinical Professor Nov 2008 – 2012 Clinical Trials Centre, Li Ka Shing Faculty of Medicine The University of Hong Kong, Hong Kong SAR Member Jul 2007 – 2012 Steering Committee on e-Health Record Sharing Food and Health Bureau, Government Secretariat, Hong Kong SAR Member Mar 2002 – 2004 Task Group on Breast Cancer Management Hospital Authority, Hong Kong SAR Member Jul 2001 – Dec 2001 Task Group on Re-development of Li Shu Fan Building The University of Hong Kong, Hong Kong SAR 2 Chow L.W.C. Honorary Secretary Feb 2001 – Dec 2004 Hong Kong Association for Integration of Chinese -Western Medicine Director Jan 2001 – Dec 2005 Hung Chao Hong Integrated Centre for Breast Diseases Tung Wah Hospital, Hong Kong SAR Editor Jun 2000 – Dec 2005 Medical Faculty News, Faculty of Medicine The University of Hong Kong, Hong Kong SAR Associate Dean (Community Relations) Jan 2000 – Mar 2001 Faculty of Medicine The University of Hong Kong, Hong Kong SAR Member Sep 1999 – Dec 2005 Board of Studies, School of Chinese Medicine The University of Hong Kong, Hong Kong SAR Deputy Director Jun 1999 – Dec 2005 Centre of Education and Training, Department of Surgery The University of Hong Kong, Hong Kong SAR Board Member Jan 1999 – Jun 1999 Steering Committee, Clinical Trial Centre The University of Hong Kong, Hong Kong SAR Fellow, Centre of Endocrinology and Diabetes Sep 1998 – Dec 2005 The University of Hong Kong, Hong Kong SAR Fellow, Cancer Research Centre Sep 1998 – Dec 2005 The University of Hong Kong, Hong Kong SAR Chairman Jun 1998 – Dec 2005 Clinical Skills Planning Group New Medical Curriculum Associate Professor Mar 1997 – Dec 2005 Department of Surgery The University of Hong Kong, Hong Kong SAR Honorary Consultant Jul 1996 – Dec 2005 Department of Surgery, Tung Wah Hospital, Hong Kong SAR Honorary Consultant Jul 1996 – Dec 2005 Department of Surgery, Queen Mary Hospital, Hong Kong SAR Chief, Division of Breast Surgery Jul 1995 – Dec 2005 The University of Hong Kong, Hong Kong SAR Assistant Professor Apr 1993 – Mar 1997 Department of Surgery, The University of Hong Kong, Hong Kong SAR 3 Chow L.W.C. PREVIOUS APPOINTMENTS IN PROFESSIONAL ASSOCIATIONS President (Asia-Africa) 2008 – 2009 Senologic International Society (SIS) Vice-President Jun 2000 – 2011 Hong Kong Day Surgery Association President Oct 1999 – Sep 2000 Asian Breast Cancer Society Honorary Secretary Jul 1995 – Jun 1997 Hong Kong Day Surgery Association Honorary Secretary Jul 1995 – Jun 1997 University Medical Doctors’ Association Council Member Jul 1995 – Jun 1997 Public Doctor Association, Hong Kong SAR PROFESSIONAL MEMBERSHIP Hong Kong: Hong Kong Medical Association International: International Society of Surgery American Association of Cancer Research Asian Surgical Association American Society of Breast Disease Breast Surgery International American Society of Breast Surgeons TEACHING DUTIES AND EXPERIENCE Courses Attended Breast Sonography Program Jun 2004 Institute of Ultrasound, St Peterburg, Florida, USA Radioguided Surgery and Minimally Invasive Breast Biopsy Jun 2001 H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA Program for Advanced Medical Education Dec 1999 Harvard Medical School, Boston, USA Courses Taught Radioguided Surgery Course, Chengdu Nov 2003 Department of Surgery Xua Shi Medical School, P.R. China Breast Cancer Understanding Cancer Broadening Courses in Culture and Value Studies and Theme Studies The University of Hong Kong 4 1999 – present Chow L.W.C. Principles of Surgical Treatment of Cancer Understanding Cancer Broadening Courses in Culture and Value Studies and Theme Studies The University of Hong Kong Management of Advanced Stage Breast Cancer 1999 – present Dec 1998 Diploma in Oncology & Palliative Care for Health Care Professionals School of Professional & Continuing Education, The University of Hong Kong Breast Cancer – Screening & Surgical Treatment Jul 1997 Diploma in Oncology & Palliative Care for Health Care Professionals School of Professional & Continuing Education, The University of Hong Kong Mock Viva on Breast Diseases Jul 1997 Advanced Course in Surgery Department of Surgery, The University of Hong Kong Management of Breast Cancer Jul 1997 Advanced Course in Surgery Department of Surgery, The University of Hong Kong Breast Cancer Apr 1997 Certificate Course in Clinical Oncology Department of Nursing Studies, The University of Hong Kong Surgery and Breast Cancer Aug 1996 Advanced Course in Breast Cancer Nursing, Hong Kong SAR Classification and Staging of Breast Cancer Aug 1996 Advanced Course in Breast Cancer Nursing, Hong Kong SAR Seminars and Interactive Teaching Tutor, Health Care Project for Phase I Students Faculty of Medicine, The University of Hong Kong, 2001 – present Lecturer, whole class session on “Breast Mass” Phase I Department of Surgery, The University of Hong Kong, Chief Co-ordinator of Teaching in Network Hospitals Phase II, Block B, Department of Surgery, The University of Hong Kong, Chief Co-ordinator of Teaching Clinic Phase I, Block B, Department of Surgery, The University of Hong Kong, PBL Tutor Phase I, Block B Department of Surgery, The University of Hong Kong, PBL – Case Writer of Breast Cancer 1998 – present 1998 – present 1997 – present Phase I, Block B, Department of Surgery, The University of Hong Kong, 1997 – present Interactive Teaching on Breast Diseases 1996 – 1999 Junior Clinical Clerkship Department of Surgery, The University of Hong Kong, 5 Chow L.W.C. Clinical Demonstration on Breast Examination Introductory Clinical Course Department of Surgery, The University of Hong Kong, Seminars and Tutorials 1995 – present 1995 – 1999 Special Clinical Clerkship Department of Surgery, The University of Hong Kong, Course Director Minimally Invasive Breast Biopsy Course Nov 2004 Department of Surgery, The University of Hong Kong, Radioguided Surgery Course for Breast Cancer Jun 2004 Department of Surgery, The University of Hong Kong, Radioguided Surgery Course for Breast Cancer Nov 2003 Department of Surgery, The University of Hong Kong, Radioguided Surgery Course for Breast Cancer Nov 2002 Department of Surgery, The University of Hong Kong, Radioguided Surgery Course for Breast Cancer Mar 2002 Department of Surgery, The University of Hong Kong, Summer Broadening Course 2001 Faculty of Medicine, The University of Hong Kong, Summer Broadening Course 2000 Faculty of Medicine, The University of Hong Kong, RESEARCH ACTIVITIES Thesis Master of Surgery Modification of acute inflammatory response phase response caused by surgical trauma in a mastectomy model Degree conferred in December 1999 Journal Articles Published 1. Case report: postradiation chondrosarcoma with a short latency period of 6 months Yang S, Tang W, Tang XF, Xuan M, Guo LJ, Wang XY, Loo WT, Liu Q, Chow LW, Cheung MN, Tsang W Int J Biol Markers 2014 Nov 8:0 2. Outcomes of adjuvant endocrine therapy and hormone receptor status change following neoadjuvant chemotherapy in breast cancer patients Wu JY, Chen WG, Chen XS, Huang O, He JR, Zhu L, Li Y, Shen KW, Chow LW, Loo WT, Chow CY, Tsang W Int J Biol Markers 2014 Nov 5:0 3. Suppression of C6 gliomas via application of rat hyperplasia gene. Gao P, Wang Z, Zhang B, Zou Y, Guo H, Liu H, Yang Q, Fang Z, Jiang S, Shen B, Chow LW, Loo WT, Ng EL, Tsang WW. Int J Biol Markers. 2014 Oct 8:0. doi: 10.5301/jbm.5000114. 6 Chow L.W.C. 4. 5. Epigenetic changes of TIMP-3, GSTP-1 and 14-3-3 sigma genes as indication of status of chronic inflammation and cancer. Wang YJ, He L, Yuan M, Tsang WW, Hao L, Wang M, Chow LW, Cheung MN, Liu Q, Ng EL, Loo WT, Chow CY, Bai LJ, Yang Z. Int J Biol Markers. 2014 Sep 30;29(3):e208-14. doi: 10.5301/jbm.5000104. Correlation of tumor-infiltrative lymphocyte subtypes alteration with neoangiogenesis before and after neoadjuvant chemotherapy treatment in breast cancer patients Chan MS, Chen SF, Felizola SJ, Wang L, Nemoto N, Tamaki K, Ishida T, Chow LW, Ohuchi N, Sasano H Int J Biol Markers 2014 Sep 30;29(3):e193-203 6. Challenges to effective cancer control in China, India, and Russia Goss PE, Strasser-Weippl K, Lee-Bychkovsky BL, Fan L, Li J, Chavarri-Guerra Y, Liedke PE, Pramesh CS, Badovinac-Crnjevic T, Sheikine Y, Chen Z, Qiao YL, Shao Z, Wu YL, Fan D, Chow LW, Wang J, Zhang Q, Yu S, Shen G, He J, Purushotham A, Sullivan R, Badwe R, Banavali SD, Nair R, Kumar L, Parikh P, Subramanian S, Chaturvedi P, Iyer S, Shastri SS, Digumarti R, Soto-Perez-de-Celis E, Adilbay D, Semiglazov V, Orlov S, Kaidarova D, Tsimafeyeu I, Tatishchev S, Danishevskiy KD, Hurlbert M, Vail C, St Louis J, Chan A Lancet Oncol 2014 Apr;15(5):489-538 7. Bosutinib in combination with the aromatase inhibitor letrozole: a phase II trial in postmenopausal women evaluating first-line endocrine therapy in locally advanced or metastatic hormone receptor-positive/HER2-negative breast cancer Moy B, Neven P, Lebrun F, Bellet M, Xu B, Sarosiek T, Chow L, Goss P, Zacharchuk C, Leip E, Turnbull K, Bardy-Bouxin N, Duvillié L, Láng I Oncologist 2014 Apr;19(4):348-9 8. Bosutinib in combination with the aromatase inhibitor exemestane: a phase II trial in postmenopausal women with previously treated locally advanced or metastatic hormone receptor-positive/HER2-negative breast cancer Moy B, Neven P, Lebrun F, Bellet M, Xu B, Sarosiek T, Chow L, Goss P, Zacharchuk C, Leip E, Turnbull K, Bardy-Bouxin N, Duvillié L, Láng I Oncologist 2014 Apr;19(4):346-7 9. Angiotensin II induces mitochondrial dysfunction and promotes apoptosis via JNK signalling pathway in primary mouse calvaria osteoblast. Li G, Wang M, Hao L, Loo WT, Jin L, Cheung MN, Chow LW, Ng EL. Arch Oral Biol. 2014 May;59(5):513-23. doi: 10.1016/j.archoralbio.2014.02.015. Epub 2014 Mar 4. 10. A pilot study: application of hemoglobin and cortisol levels, and a memory test to evaluate the quality of life of breast cancer patients on chemotherapy. Loo WT, Yip MC, Chow LW, Liu Q, Ng EL, Wang M, Chen J. Int J Biol Markers. 2013 Dec 17;28(4):e348-56. doi: 10.5301/jbm.5000053. 11. Randomized trial of preoperative docetaxel with or without capecitabine after 4 cycles of 5-fluorouracil– epirubicin–cyclophosphamide (FEC) in early-stage breast cancer: exploratory analyses identify Ki67 as a predictive biomarker for response to neoadjuvant chemotherapy Ohno S, Chow LW, Sato N, Masuda N, Sasano H, Takahashi F, Bando H, Iwata H, Morimoto T, Kamigaki S, Nakayama T, Nakamura S, Kuroi K, Aogi K, Kashiwaba M, Yamashita H, Hisamatsu K, Ito Y, Yamamoto Y, Ueno T, Fakhrejahani E, Yoshida N, Toi M Breast Cancer Res Treat 2013 Nov;142(1):69-80 7 Chow L.W.C. 12. Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2positive metastatic breast cancer Chow LW, Xu B, Gupta S, Freyman A, Zhao Y, Abbas R, Vo Van ML, Bondarenko I Br J Cancer 2013 May 28;108(10):1985-93 13. Comparative evaluation of cytokines in gingival crevicular fluid and saliva of patients with aggressive periodontitis Yue Y, Liu Q, Xu C, Loo WT, Wang M, Wen G, Cheung MN, Bai LJ, Dou YD, Chow LW, Hao L, Tian Y, Li JL, Yip AY, Ng EL Int J Biol Markers 2013 Apr 23;28(1):108-12 14. New developments in breast cancer prognosis: molecular predictors of treatment response and survival Foo EM, Boost MV, Wong AS, Loo WT, Chow LW, Chow CY Int J Biol Markers 2013 Jun 28;28(2):e131-40 15. Status of oral ulcerative mucositis and biomarkers to monitor posttraumatic stress disorder effects in breast cancer patients Loo WTY, Liu Q, Yip MCW, Wang M, Chow LWC, Cheung MNB, Yip AYS, Ng ELY Int J Biol Markers 2013 Jun 28;28(2):e168-73 16. Acceptable cardiac safety profile of neoadjuvant 5 -fluorouracil, epirubicin, cyclophosphamide and celecoxib (FEC-C) for breast cancer: a subanalysis of biomarkers for cardiac injury Chow LWC, Loo WTY, Yip AYS, Ng ELY Int J Biol Markers 2013 Apr 23;28(1):e92-9 17. Application of interleukin-1 genes and proteins to monitor the status of chronic periodontitis Hao L, Li JL, Yue Y, Tian Y, Wang M, Loo WTY, Cheung MNB, Chow LWC, Liu Q, Yip AYS, Ng ELY Int J Biol Markers 2013 Apr 23;28(1):e92-9 18. Application of biomarkers to sentinel lymph node biopsy for the management of breast cancer Liu Q, Loo WTY, Yip AYS, Chow LWC, Ng ELY, Cheung MNB Chinese Journal of Breast Disease 2013 Mar 21 19. Association of cytokines, high sensitive C -reactive protein, VEGF and beta defensin-1 gene polymorphisms and their protein expressions with chronic periodontitis in the Chinese population Tian Y, Li JL, Hao L, Yue Y, Wang M, Loo WTY, Cheung MNB, Chow LWC, Liu Q, Yip AYS, Ng ELY, Chow CY Int J Biol Markers 2013 Apr 23;28(1):e100-e107 20. Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study Chow LWC, Tung SY, Ng TY, Im SA, Lee MH, Yip AYS, Toi M, Glück S Expert Opin Investig Drugs 2013 Mar;22(3):299-307 8 Chow L.W.C. 21. Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer Wolff AC, Lazar AA, Bondarenko I, Garin AM, Brincat S, Chow LWC, Sun Y, Neskovic-Konstantinovic Z, Guimaraes RC, Fumoleau P, Chan A, Hachemi S, Strahs A, Cincotta M, Berkenblit A, Krygowski M, Kang LL, Moore L, Hayes DF J Clin Oncol 2012 Dec 10 22. Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients - an immunohistochemical study of cd8+ and foxp3+ using double immunostaining with correlation to the pathobiological response of the patients Chan MSM, Wang L, Felizola SJA, Ueno T, Toi M, Loo WTY, Chow LWC, Suzuki T, Sasano H Int J Biol Markers 2012 Dec 27;27(4):e295-304 23. Evaluation of the psychological and biological changes of patients diagnosed with benign and malignant breast tumors. Bai LJ, Liu Q, Wang M, Loo WTY, Cheng RWY, Chow LWC, Cheung MNB, Wei KYR, Yip AYS, Ng ELY Int J Biol Markers 2012 Dec 27;27(4):e322-30 24. Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis Xu C, Zhao J, Loo WT, Hao L, Wang M, Cheung MNB, Dou Y, Yip AYS, Ng ELY, Chow LWC, Liu Q Int J Biol Markers 2012 Dec 27;27(4):e314-21 25. The clinical trials of the Organisation for Oncology and Translational Research (OOTR) Chow LWC, Toi M Int J Biol Markers 2012 Dec 27;27(4):e353-6 26. Prevention of oncological diseases: primary and secondary prevention Chow LWC, Yip AYS, Ng ELY Int J Biol Markers 2012 Dec 27;27(4):e337-43 27. Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference Toi M, Benson JR, Winer EP, Forbes JF, von Minckwitz G, Golshan M, Robertson JF, Sasano H, Cole BF, Chow LWC, Pegram MD, Han W, Huang CS, Ikeda T, Kanao S, Lee ES, Noguchi S, Ohno S, Partridge AH, Rouzier R, Tozaki M, Sugie T, Yamauchi A, Inamoto T Breast Cancer Res Treat 2012 Dec;136(3):919-26 28. 具抗药性乳腺癌病人的组合性用药治疗方案及其疗效和监察的探讨 Chow LWC, Yip AYS, Liu Q, Loo WTY The 15th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book, People’s Medical Publishing House, 243-242 29. Minimally invasive video-assisted thyroidectomy for the early-stage differential thyroid carcinoma Yu JJ, Bao SL, Yu SL, Zhang DQ, Loo WTY, Chow LWC, Su L, Cui Z, Chen K, Ma LQ, Zhang N, Yu H, Yang WZ, Dong Y, Yip AYS, Ng ELY J of Translational Medicine 2012, 10 Suppl 1: S13 9 Chow L.W.C. 30. Using association rules mining to explore pattern of Chinese medicinal formulae (prescription) in treating and preventing breast cancer recurrence and metastasis He Y, Zheng X, Sit C, Loo WTY, Wang ZY, Xie T, Jia B, Ye QB, Tsui KC, Chow LWC, Chen JP J of Translational Medicine 2012, 10 Suppl 1: S12 31. Mouse model of plasma cell mastitis Yu JJ, Bao SL, Yu SL, Zhang DQ, Loo WTY, Chow LWC, Su L, Cui Z, Chen K, Ma L Q, Zhang N, Yu H, Yang YZ, Dong Y, Yip AYS, Ng ELY J of Translational Medicine 2012, 10 Suppl 1: S11 32. Clinical application of human β-defensin and CD14 gene polymorphism in evaluating the status of chronic inflammation Loo WTY, Bai LJ, Fan CB, Yue Y, Dou YD, Wang M, Liang H, Cheung MNB, Chow LWC, Li JL, Tian Y, Qing L J of Translational Medicine 2012, 10 Suppl 1: S9 33. Gene polymorphism and protein of human pro - and anti-inflammatory cytokines in Chinese healthy subjects and chronic periodontitis patients Loo WTY, Fan CB, Bai LJ, Yue Y, Dou YD, Wang M, Liang H, Cheung MNB, Chow LWC, Li JL, Tian Y, Qing L J of Translational Medicine 2012, 10 Suppl 1: S8 34. Emodin affects ERCC1 expression in breast cancer cells Fu JM, Zhou J, Shi J, Xie JS, Huang L, Yip AYS, Loo WTY, Chow LWC, Ng ELY J of Translational Medicine 2012, 10 Suppl 1: S7 35. Relationship of CD44+CD24-/low breast cancer stem cells and axillary lymph node metastasis Wei W, Hu H, Tan HS, Chow LWC, Yip AYS, Loo WTY J of Translational Medicine 2012, 10 Suppl 1: S6 36. Comparing serum levels of cardiac biomarkers in cancer patients receiving chemotherapy and subjects with chronic periodontitis Loo WTY, Yue Y, Fan CB, Bai LJ, Dou YD, Wang M, Liang H, Cheung MNB, Chow LWC, Li J, Tian Y, Qing L J of Translational Medicine 2012, 10 Suppl 1: S5 37. Overexpression of epithelial growth factor receptor (EGFR) predict better response to neo-adjuvant chemotherapy in patients with triple-negative breast cancer Tang YQ, Zhu L, Li YF, Ji J, Li JF, Yuan F, Wang DB, Chen WG, Huang O, Chen XS, Wu JY, Shen KW, Loo WTY, Chow LWC J of Tranlsational Medicine 2012 10 Suppl 1: S4 38. Decreased Expression of C-erbB-2 and CXCR4 in Breast Cancer after Primary Chemotherapy Yang SX, Loo WTY, Chow LWC, Yang XH, Zhan Y, Fan LJ, Zhang F, Li C, Wang QL, Xiao HL, Wu JL, Bian XW, Jiang J J of Tranlsational Medicine 2012 10 Suppl 1: S3 39. LMTK3 is implicated in endocrine resistance via multiple signaling pathways Stebbing J, Filipovic A, Lit LC, Blighe K, Grothey A, Xu Y, Miki Y, Chow LWC, Coombes RC, Sasano H, Shaw JA, Giamas G Oncogene 2012 Aug 6 10 Chow L.W.C. 40. Association of matrix metalloproteinase (MMP) -1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chronic periodontitis in a Chinese population Li GY, Yue Y, Tian Y, Li JL, Wang M, Liang H, Liao P X, Loo WTY, Cheung MNB, Chow LWC Cytokine 2012 Nov;60(2):552-60 41. New therapies in HER2-positive breast cancer: a major step towards a cure of the disease? Awada A, Bozovic-Spasojevic I, Chow LWC Cancer Treat Rev 2012; 38: 494-504 42. Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique Takada M, Sugimoto M, Ohno S, Kuroi K, Sato N, Bando H, Masuda N, Iwata H, Kondo M, Sasano H, Chow LWC, Inamoto T, Naito Y, Tomita M, Toi M Breast Cancer Res Treat 2012; 134: 661-670 43. Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1 Shibahara Y, Miki Y, Onodera Y, Hata S, Chan MS M, Yiu CCP, Loo WTY, Nakamura Y, Akahira JI, Ishida T, Abe K, Hirakawa H, Chow LWC, Suzuki T, Ouchi N, Sasano H J Pathol 2012; 227: 357-366 44. Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis Wang ZY, Loo WTY, Wang N, Chow LWC, Wang DM, Han F, Zheng X, Chen JP Expert Opin Ther Targets 2012; 16 Suppl 1: S79-89 45. Effects of estrogen depletion on angiogenesis in estrogen -receptor-positive breast carcinoma--an immunohistochemical study of vasohibin -1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy Chan MS, Wang L, Chanplakorn N, Tamaki K, Ueno T, Toi M, Loo WTY, Chow LWC, Suzuki T, Sasano H Expert Opin Ther Targets 2012; 16 Suppl 1: S69-78 46. Translational research to realize the full potential of novel agents --an opportunity for vinflunine? Yip AY, Ong EY, Chow LW Expert Opin Drug Saf 2012; 11 Suppl 1: S5-8 47. Increased 5α-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: the correlation with decreased tumor cell proliferation Chanplakorn N, Chanplakorn P, Suzuki T, Ono K, Wang L, Chan MS, Wing L, Yiu CC, Chow LWC, Sasano H Horm Cancer 2011; 2: 73-81 48. Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: sub -analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial Chow LWC, Yip AYS, Chu WP, Loo WT, Toi M J Steroid Biochem Mol Biol 2011; 125(1-2): 112-119 11 Chow L.W.C. 49. Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint Wang ZY, Wang DM, Loo TY, Cheng Y, Chen LL, Shen JG, Yang DP, Chow LWC, Guan XY, Chen JP J Ethnopharmacol 2011; 133: 751-1780 50. Year in review in Asia - The major Asian trials published in 2011 on Breast Cancer Chow LWC, Yip AYS, Chu WP, Ong EYY The Journal of Japan Society of Clinical Oncology 2011; 46: 1176-1181 51. Racial differences in acute toxicities of neoadjuvant or adjuvant chemotherapy in patients with early-stage breast cancer Han HS, Reis IM, Zhao W, Kuroi K, Toi M, Suzuki E, Syme R, Chow LWC, Yip AYS, Glück S Eur J Cancer 2011; 47: 2537-45 52. Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: Sub -analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial Chow LWC, Yip AYS, Chu WP, Loo WTY, Toi M J Steroid Biochem Mol Biol 2011; 125 (1-2) : 112-9 53. Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis Loo WTY, Jin L, Cheung MNB, Wang M, Chow LWC J Transl Med 2010; 8: 110 54. Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients Yiu CC, Chanplakorn N, Chan MS, Loo WT, Chow LW C, Toi M, Sasano H Anticancer Res 2010; 30: 3465-3472 55. The Breast Cancer Working Group presentation was divided into three sections: the epidemiology, pathology and treatment of breast cancer Toi M, Ohashi Y, Seow A, Moriya T, Tse G, Sasano H, Park BW, Chow LW, Laudico AV, Yip CH, Ueno E, Ishiguro H, Bando H Jpn J Clin Oncol 2010; 40 Suppl 1: i13-18 56. Rhodiola algida improves chemotherapy -induced oral mucositis in breast cancer patients Loo WTY, Jin LJ, Chow LWC, Cheung MNB, Wang M Expert Opin Investig Drugs 2010; 19 Suppl 1: S91-S100 57. Changes in protein expression after neoadjuvant use of aromatase inhibitors in primary breast cancer: a proteomic approach to search for potential biomarkers to predict response or resistance Yiu CCP, Sasano H, Ono K, Chow LWC Expert Opin Investig Drugs 2010; 19 Suppl 1: S79-S89 58. Combat against cancer with science and medicine Chow LWC, Toi M Expert Opin Investig Drugs 2010; 19 Suppl 1: S3-S4 12 Chow L.W.C. 59. Gene expression profiles as an additional tool to conventional predictive factors to assist in management of early endocrine responsive breast cancer Chow LWC Expert Opin Investig Drugs 2010; 19 Suppl 1: S13-S17 60. Combination of radiological and biochemical methods to assess bone mineral density of mandible in fully edentulous patients after chemotherapy: a 5-year prospective study Loo WTY, Jin LJ, Cheung MNB, Chow LWC, Wang M Expert Opin Investig Drugs 2010; 19 Suppl 1: S109-S115 61. Expression of CD44V6 in parotid pleomorphic adenoma and carcinoma ex pleomorphic adenoma Yang S, Wang HP, Wang XY, Guo LJ, Tang XF, Gao QH, Xuan M, Loo WTY, Chow LWC Expert Opin Investig Drugs 2010; 19 Suppl 1: S101-S108 62. Survival benefits from lapatinib therapy in women with HER2 -overexpressing breast cancer: a systematic review Yip AYS, Tse LA, Ong EYY, Chow LWC Anticancer Drugs 2010; 21: 487-493 63. Neratinib (HKI-272) 聯合紫杉醇治 ErbB2+ 中國轉移性乳腺癌患者的安全性及有 效性 江澤飛, 徐兵河, 楊俊蘭, Epstein R, Coughlin CM, Freyman A, Zhao Y, 孫強, 李維 廉, Kwong A, 周永昌 Linchuang Zhongliuxue Zazhi 2009; 60-61 64. 乳腺癌新輔助化療 Yip AYS, Ong EYY, Yiu CCP, Chow LWC th The 12 Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book. Chinese Peking Union Medical College Press 2009; pp525-529 65. Breast cancer management: the way forward Yip AYS, Chow LWC Hong Kong Med J 2009; 15: 244-245 66. Expression of thymidine phosphorylase and dihydropyrimidine dehydrogenase in human breast carcinoma cells and tissues Loo WTY, Chow LWC, Suzuki T, Ono K, Ishida T, Hirakawa H, Ohuchi N, Sasano H Anticancer Res 2009; 29: 2525-2530 67. Presence of extensive intraductal component in patients undergoing breast conservative surgery predicts presence of residual disease in subsequent completion mastectomy Yiu CCP, Loo WTY, Lam CK, Chow LWC Chin Med J (Engl) 2009; 122: 900-905 68. Increased expression of annexin I is associated with drug -resistance in nasopharyngeal carcinoma and other solid tumors Chow BH, Chua DT, Sham JS, Zhang MY, Chow LW C, Bi J, Ma NF, Xie D, Loo WT, Fung JM, Fu L, Guan XY Proteomics Clin Appl 2009; 3: 654-662 69. Latest world development in breast cancer treatment [Article in Chinese] Yip AYS, Chow LWC Chinese Journal of Breast Disease (Electronic Edition) 2009; 3:215-222 13 Chow L.W.C. 70. Novel therapeutic strategy for breast cancer: mammalian target of rapamycin inhibition Yip AYS, Ong EYY, Chow LWC Expert Opin Drug Discov 2009; 4:457-466 71. Current treatment of locally advanced and metastatic breast cancer in the Asia – Pacific region: Challenges and limitations Chow LWC, Im YH Asia Pac J Clin Oncol 2009; 4:S14-S23 72. Breast-conserving surgery in Hong Kong Chinese women Suen D, Chow LWC, Kwong A World J Surg 2008; 32: 2549-2553 73. Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer Chow LWC, Yip AYS, Loo WTY, Lam CK, Toi M J Steroid Biochem Mol Biol 2008; 111: 13-17 74. Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer Gomez HL, Doval DC, Chavez MA, Ang PC, Aziz Z, Nag S, Ng C, Franco SX, Chow LWC, Arbushites MC, Casey MA, Berger MS, Stein SH, Sledge GW. J Clin Oncol 2008; 26: 2999-3005 75. Evaluation of neoadjuvant inhibition of aromatase activity and signal transduction in breast cancer Chow LWC, Yip AYS, Loo WTY, Toi M Cancer Lett 2008; 262: 232-238 76. Vinflunine: Clinical perspectives of an emerging anticancer agent Yip AYS, Ong EYY, Chow LWC Expert Opin Investig Drugs 2008; 17: 583-591 77. Factors predicting seroma formation after mastectomy for Chinese breast cancer patients Loo WTY, Chow LWC Indian J Cancer 2007; 44: 99-103 78. PTEN and VEGF: possible predictors for sentinel lymph node mi cro-metastasis in breast cancer Zhu L, Loo WT, Chow LWC Biomed Pharmacother 2007; 61: 558-561 79. Fructus Schisandrae (Wuweizi) containing compound in modulating human lymphatic system – a Phase I minimization clinical trial Yip AYS, Loo WTY, Chow LWC Biomed Pharmacother 2007; 61: 588-590 80. Neoadjuvant chemotherapy for breast cancer determined by chemosensitivity assay achieves better tumor response Lau GI, Loo WT, Chow LWC Biomed Pharmacother 2007; 61: 562-565 14 Chow L.W.C. 81. Effects of Shugansanjie Tang on matrix metalloproteinases 1, 3 and 9 and telomerase reverse transcriptase expression in human breast cells in vitro Loo WTY Chen JP, Chow LWC, Chou JW Biomed Pharmacother 2007; 61: 601-605 82. Evaluation of therapeutic efficacy of capecitabine on human breast carcinoma tissues and cell lines in vitro Loo WTY, Sasano H, Chow LWC Biomed Pharmacother 2007; 61: 553-557 83. Fructus schisandrae (Wuweizi) containing compound inhibits secretion of HBsAg and HBeAg in hepatocellular carcinoma cell line. Loo WTY, Cheung MNB, Chow LWC Biomed Pharmacother 2007; 61: 606-610 84. Effects of capecitabine and vinorelbine on cell proliferation, metabolism and COX2 and p16 expression in breast cancer cell lines and solid tumour tissues. Loo WTY, Sasano H, Chow LWC Biomed Pharmacother 2007; 61: 596-600 85. Pro-inflammatory cytokine, matrix metalloproteinases and TIMP-1 are involved in wound healing after mastectomy in invasive breast cancer patients. Loo WTY, Sasano H, Chow LWC Biomed Pharmacother 2007; 61: 548-552 86. Chrysomya bezziana: a rare infestation of the breast Kwong A, Yiu WK, Chow LWC, Wong S Breast J 2007; 13: 297-301 87. A phase II trial of vinorelbine and pegylated liposomal doxorubicin in patients with pretreated metastatic breast cancer Chow LWC, Yip AYS, Lang BHH Am J Clin Oncol 2007; 30: 133-138 88. A randomized controlled trial of psychosocial interventions using the psychophysiological framework for Chinese breast cancer patients Chan CL, Ho RT, Lee PW, Cheng JY, Leung PP, Foo W, Chow LW C, Sham JS, Spiegel D J Psychosoc Oncol 2006; 24: 3-26 89. Breast cancer in limited-resource countries: an overview of the Breast Health Global Initiative 2005 guidelines Anderson BO, Shyyan R, Eniu A, Smith RA, Yip CH, Bese NS, Chow LW C, Masood S, Ramsey SD, Carlson RW Breast J 2006; 12 Suppl 1:S3-S15 90. A new predictive and prognostic marker (ATP bioluminescence and positron emission tomography) in vivo and in vitro for delivering adjuvant treatment plan to invasive breast tumor patient Loo WTY, Tong JM, Cheung MN, Chow LWC Biomed Pharmacother 2006; 60: 285-288 91. Prognostic contribution of the HER-2 oncogene overexpression to the Nottingham Prognostic Index in breast cancer Suen D, Chow LWC Biomed Pharmacother 2006; 60: 293-297 15 Chow L.W.C. 92. Increase in circulating VEGF levels during COX-2 inhibitor treatment in breast cancer patients Ueno T, Chow LWC, Toi M Biomed Pharmacother 2006; 60: 277-279 93. Clinical experience with docetaxel for Chinese breast cancer patients: hematological toxicity profiles Yip AYS, Chow LWC Breast Cancer 2006; 13: 192-196 94. Possible predictive markers related to micro-metastasis in breast cancer patients Zhu L, Loo WTY, Cheng CW, Chow LWC Oncol Rep 2006; 15:1217-1223 95. Cyclooxygenase-2 and Angiogenesis in Oncology (Editorial) Chow LWC, Toi M Biomed Pharmacother 2005; 59 Suppl 2: S263 96. The efficacy of Paclitaxel on solid tumor analysed by ATP bioluminescence assay and VEGF expression: A translational research study Loo WTY, Fong JHM, Cheung MNB, Chow LWC Biomed and Pharmacother 2005; 59 Suppl 2: S337-S339 97. The value of bone marrow aspirates culture for detection of bone marrow micrometastasis in breast cancer Loo WTY, Fong JHM, Zhu L, Cheung MNB, Chow LWC Biomed and Pharmacother 2005; 59 Suppl 2: S384-S386 98. Study of COX-2, Ki67 and p53 are used to predict the chances of successful chemotherapy treatment in breast cancer patients Chow LWC, Loo WTY, Wai CCY, Lui ELH, Zhu L, Toi M Biomed and Pharmacother 2005; 59 Suppl 2: S298-S301 99. DNA Hypermethylation of TIMP3 gene in invasive breast carcinoma affect the outcome of the treatment Lui ELH, Loo WTY, Zhu L, Cheung MNB, Chow LWC Biomed and Pharmacother 2005; 59 Suppl 2: S363-S365 100. Current Directions for COX-2 Inhibition in Breast Cancer Chow LWC, Toi M Biomed and Pharmacother 2005; 59 Suppl 2: S281-S284 101. Aberrant methylation of cyclooxygenase-2 in breast cancer patients Chow LWC, Zhu L, Loo TY, Lui ELH Biomed and Pharmacother 2005; 59 Suppl 2: S264-S267 102. Circulating tumor cells in patients with breast cancer: predictor of micrometastasis in bone marrow but not in sentinel lymph nodes Zhu L, Loo TYW, Chow LWC Biomed and Pharmacother 2005; 59 Suppl 2: S355-S358 103. Serum lipid profiles in patients receiving endocrine treatment for breast cancer - the results from the Celecoxib Anti-Aromatase Neuoadjuvant (CAAN)Trial Chow LWC, Cheng CWN, Wong JLN, Toi M Biomed and Pharmacother 2005; 59 Suppl 2: S302-S305 16 Chow L.W.C. 104. Trastuzumab: updates and future issues Toi M, Horiguchi K, Bando H, Saji S, Chow LW C Cancer Chemother Pharmacol 2005; 56 Suppl 1: S94-S99 105. The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer Cheng CK, Chow LWC, Loo WTY, Chan TK, Chan V Cancer Res 2005; 65: 8646-8654 106. Phase II study on an “all oral” regimen of capecitabine, idarubicin and cyclophosphamide of metastatic breast cancer: safety, efficacy and quality of life Tong DKH, Cheng CW, Chan SC, Wong LNJ, Chow LWC Oncology 2005; 68: 520-525 107. Association between body mass index and the risk of formation of breast cancer in Chinese women Chow LWC, Lui KL, Chan JC, Chan TC, Ho PK, Lee WY, Leung LH, Sy WM, Yeung CC, Yung AK Asian J Surg 2005; 28: 179-184 108. The Chinese Medical Interview Satisfaction Scale -revised development and validation Lam WW, Fielding R, Chow LW, Chan M, Leung GM, Ho EY. Qual Life Res 2005; 14:1187-1192 109. Translational Research in Breast Cancer Toi M, Takebayashi Y, Chow LWC Breast Cancer 2005; 12: 86-90 110. Thymidine phosphorylase (platelet-derived endothelial-cell growth factor) in cancer biology and treatment. Toi M, Rahman MA, Bando H, Chow LWC Lancet Oncol 2005; 6:158-166 111. Gambling with your life: The process of breast cancer treatment decision making in Chinese women Lam WW, Fielding R, Chan M, Chow L, Or A Psychooncology 2005; 14: 1-15 112. Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence Tse EYT, Chow LWC, Loo WTY, Cheng CW Life Sci 2004; 76: 827-834 113. Production of matrix metalloproteinase in specific subpopulations of human patient breast cancer invading in 3-dimensional culture system Loo TYW, Chow LWC, Cheung MB Life Sci 2004; 76 :743-752 114. Novel insights in clinical trials with preoperative systemic therapy for primary breast cancer Toi M, Bando H, Chow LWC Biomed Pharmacother 2004; 58: 531-535 115. The inhibitory effects of a herbal formula comprising ginseng and carthamus tinctorius on breast cancer Loo WTY, Chow LWC, Sham JST Life Sci 2004; 76: 191-200 17 (C-MISS-R): Chow L.W.C. 116. Sentinel lymph node biopsy – here to stay (Editorial) Chow LWC Asian J Surg 2004; 27: 255 117. Sentinel lymph node biopsy or detection of micrometastasis in bone marrow: Which might be an alternative to axillary local lymph node dissection in breast cancer patients? Zhu L, Lam CK, Chow LWC Asian J Surg 2004; 27: 279-283 118. Radix bupleuri containing compound (KY88 liver -livo) induces apoptosis and production of interleukin-4 and tumor necrosis factor-α in liver cancer cells in vitro Chow LWC, Loo WTY, Sham JST, Cheung MNB Am J Chin Med 2004; 32: 185-193 119. Her2/neu expression predicts the response to antiaAromatase neoadjuvant therapy in advanced breast cancer: subgroup analysis from CAAN Trial Zhu L, Chow LWC, Loo WTY, Guan XY, Toi M Clin Cancer Res 2004; 10: 4639-4644 120. Sentinel lymph node technique for breast cancer: Radiation safety issues for radioguided surgery Law M, Chow LWC, Lam CK, Kwong A, Yiu CCP Semin Oncol 2004; 31:298-303 121. Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer: preliminary report Chow LWC, Wong LNJ, Toi M J Steroid Biochem Mol Biol 2003; 86:443-447 122. Patient effective dose of sentinel lymph node lymphoscintigraphy in breast cancer: a study using female humanoid phantom and thermoluminescent dosimeters Law M, Cheng KC, Wu PM, Ho WY, Chow LWC Br J Radiol 2003; 76: 818-823 123. Pattern of alternative medicine usage among the Chinese breast cancer patients: implication for service integration Abdullah ASM, Lau Y, Chow LWC Am J Chin Med 2003; 31: 649-658 124. Tumor-derived aberrant methylation in plasma of invasive ductal breast cancer patients: clinical implications Hu XC, Wong I, Chow LWC Oncol Rep 2003; 10: 1811-1815 125. Participation and satisfaction with surgical treatment decision -making in breast cancer among Chinese women Lam W, Fielding R, Chan M, Chow L, Ho E Breast Cancer Res Treat 2003; 80: 171-180 126. Prospective pilot study of the preoperative use of celecoxib and FEC for locally advanced breast cancer Chow LWC, Toi M Breast 2003; 12 Suppl 1:S40 18 Chow L.W.C. 127. The study of cytokine dynamics at the operation site after mastectomy Chow LWC, Loo WTY, Yuen KY, Cheng C Wound Repair Regen 2003; 11: 326-330 128. The differential effects of cyclophosphamide, epirubicin and 5-fluorouracil on apoptotic marker (CPP-32), pro-apoptotic protein (p21WAF-1) and antiapoptotic protein (bcl-2) in breast cancer cells Chow LWC, Loo TYW Breast Cancer Res Treat 2003; 80: 239-244 129. A rat cell line derived from DMBA-induced mammary carcinoma Chow LWC, Cheung MNB, Loo WTY, Guan XY Life Sci 2003; 73: 27-40 130. Polysaccharide peptide mediates apoptosis by up -regulating p21 gene and down-regulating cyclin D1 gene Chow LWC, Lo CS, Loo WT, Hu XC, Sham JST Am J Chin Med 2003; 31: 1-9 131. Breast sentinel lymph node biopsy using radioisotope injection: is one -day better than two-day protocol? Chok SH, Chow LWC, Wong KH, Cheng KC, Ho WY Am Surg 2003; 69: 358-361 132. Surgery-related shedding of breast cancer cells as determined by RT -PCR assay Hu XC, Loo TY, Chow LWC J Surg Oncol 2003; 82: 228-232 133. Immunomagnetic tumor cell enrichment is promising in detecting circulating breast cancer cells Hu XC, Wang Y, Shi DR, Loo TY, Chow LWC Oncology 2003; 64: 160-165 134. Cytokine production by human lymphocytes stimulated by a herbal compound containing Bupleurum (KY88 LIVER LIVO) Chow LWC, Loo TYW, Sham JST Acta Pharmacol Sinica 2003; 24: 140-144 135. Application of image-guided biopsy for impalpable breast lesions in Chinese women Tsang FHF, Lo JJ, Wong JLN, Lee FCW, Chow LWC ANZ J Surg 2003; 73: 23-25 136. Comparison of TPS with CEA and CA 15.3 in follow -up of Chinese breast cancer patients Hu XC, Day W, Jones B, Loo TY, Chow LWC Anticancer Res 2002; 22: 1865-1868 137. E-cadherin promoter methylation can regulate its expression in invasive ductal breast cancer tissue in Chinese woman Hu XC, Loo WTY, Chow LWC Life Sci 2002; 71: 1397-1404 138. Early introduction of clinical skills teaching in a medical curriculum —factors affecting students' learning Lam TP, Irwin M, Chow LWC, Chan P Med Educ 2002; 36: 233-240 19 Chow L.W.C. 139. Effects of a herbal compound containing bupleurum on human lymphocytes Chow LWC, Loo WTY, Sham JST Hong Kong Med J 2001; 7: 408-413 140. Clinical value of serum tumor markers in breast cancer patients Hu XC, Loo WTY, Chow LWC Chin Med J 2001; 114: 6 141. Sentinel lymph node biopsy for breast cancer Ng KKC, Chow LWC Ann Coll Surg HK 2001; 5: 116-120 142. Neoadjuvant chemotherapy for Chinese women with locally advanced breast cancer Chow LWC, Day W, Ng KCK Am Surg 2001; 67: 412-416 143. Detection of circulating breast cancer cells with multiple -marker RT-PCR assay Hu XC, Chow LWC Anticancer Res 2001; 21: 421-424 144. The use of focus group interviews in Asian medical education evaluative research Lam TP, Irwin M, Chow LWC, Chan P Med Educ 2001; 35: 510-513 145. The impact of postoperative nausea and vomiting on the practice of day surgery for Chinese women with breast diseases Choi HK, Chow LWC, Goh LC, Tsui SL, Lee F Ambul Surg 2001; 9: 29-32 146. Clarithromycin attenuates mastectomy-induced acute inflammatory response Chow LWC, Yuen KY, Woo PCY, Wei WI Clin Diagn Lab Immunol 2000; 7: 925-931 147. Fine needle aspiration may shed breast cells into peripheral blood as determined by RT-PCR Hu XC, Chow LWC Oncology 2000; 59: 217-222 148. Hormonal receptor determination of 1,052 Chinese breast cancers Chow LWC, Ho P J Surg Oncol 2000; 75: 172-175 149. Practice of breast self-examination among high risk Chinese women in Hong Kong Ng KKC, Fung SY, Chow LWC Chin Med J 2000; 113: 1110-1113 150. Detection of circulating breast cancer cells by reverse transcriptase polymerase chain reaction (RT-PCR) Hu XC, Chow LWC Eur J Surg Oncol 2000; 26: 530-535 151. MR appearance of metastatic melanotic melanoma in the breast Ho LWC, Wong KP, Chan JH, Chow LWC, Leung EYF, Leong L Clin Radiol 2000; 55: 572-573 20 Chow L.W.C. 152. Comparison of tamoxifen with danazol in the management of idiopathic gynecomastia Ting ACW, Chow LWC, Leung YF Am Surg 2000; 66: 38-40 153. Acute myeloid leukemia relapsing as gynecomastia Au WY, Ma ESK, Kwong YL, Lie AKW, Shek WH, Chow LWC, Liang R Leuk Lymphoma 1999; 36: 191-194 154. Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer Khoo US, Ozcelik H, Cheung ANY, Chow LWC, Ngan HYS, Au GKH, Man EPS, Chan V, Ng WF, Poon CSP, Leung YF, Loong F, Ip P, Chan GSW, Andrulis IL, Ho FCS Oncogene 1999; 18: 4643-4646 155. Clarithromycin attenuates the inflammatory response induced by surgical trauma in a guinea pig model Woo PCY, Chow LWC, Ma ESK, Yuen KY Pharmacol Res 1999; 39: 49-54 156. Bleeding peptic ulcer: an evolving role for surgical intervention Branicki FJ, Ting ACW, Gertsch P, Tuen HH, Chu KM, Chow LWC, Wong J J Gastroenterol Hepatol 1998; 13 Suppl: S227-S231 157. Comparison of antiemetic efficacy of granisetron and ondansetron in Chinese patients receiving chemotherapy for breast cancer: a randomised crossover study Poon RTP, Chow LWC Br J Cancer 1998; 77: 1683-1685 158. Bleeding peptic ulcer in the very elderly: risk factors for re-bleeding and mortality Chow LWC, Gertsch P, Poon RTP, Branicki FJ Br J Surg 1998; 85: 121-124 159. Lymphoma of the breast in Hong Kong Chinese Au WY, Chan ACL, Chow LWC, Liang R Haem Oncol 1997; 15: 33-38 160. p53 expression in recurrent nodal metastases from nasopharyngeal carcinoma Chow LWC, Khoo US, Yuen APW, Wei WI Eur J Surg Oncol 1997; 23: 415-418 161. Wide margin excision and brachytherapy for post -radiation breast cancer recurrence Chow LWC, Cheng ACK, Lam LK, Ho CM, Au GKH J Surg Oncol 1997; 65: 55-56 162. Breast conservative therapy for invasive breast cancer in Hong Kong: factors affecting recurrence and survival in Chinese women Chow LWC, Au GKH, Poon RTP Aust NZ J Surg 1997; 67: 94-97 163. Immunohistochemical analysis of antimeatstatic gene NM23 in human breast carcinoma Khoo US, Loong F, Chow LWC, Cheung KL, Ng WF, Cheung ANY Pathol Int 1997; 47: A7 21 Chow L.W.C. 164. Bleeding peptic ulcer in Hong Kong: stratification of risk factors in 1441 patients Chow LWC, Ting ACW, Gertsch P, Branicki FJ Asian J Surg 1997; 20: 279-282 165. Current status of breast cancer in Hong Kong Chow LWC, Ting ACW, Cheung KL, Au GKH, Alargaratnam TT Chin Med J 1997; 110: 474-478 166. Thoracoscopic vagotomy for the treatment of recurrent peptic ulcer after surgery Poon RTP, Chow LWC, Lim BH, Gertsch P Aust NZ J Surg 1997; 67: 177-180 167. Laparoscopic Taylor’s procedure in Chinese patients Gertsch P, Chow LWC, Lim BH Gastrointest Endosc 1996; 43: 243-247 168. Long term survival time after gastrectomy for advanced bleeding or perforated gastric carcinoma Gertsch P, Chow LWC, Yuen ST, Chau KY, Lauder IJ Eur J Surg 1996; 162: 723-727 169. Update article – conservative breast surgery for breast cancer Poon RTP, Chow LWC, Au GKH Hong Kong Practitioner 1996; 18: 68-72 170. Intrapancreatic avulsion of the common bile duct after blunt abdominal trauma Chow LWC, Gertsch P, Cheung KL, Leung SYL Eur J Surg 1996; 162: 519-521 171. Atrophy of hand muscles and gastric cancer – coincidence or a paraneoplastic manifestation Chow LWC South Med J 1995; 88: 961-963 172. Gastric cancer with synchronous liver metastasis: palliative gastrectomy or not? Chow LWC, Lim BH, Leung SYL, Branicki FJ, Gertsch P Aust NZ J Surg 1995; 65: 719-723 173. Pyogenic hepatic abscess and carcinoma of colon Chow LWC, Lo CY, Ng WK, Gertsch P Illustrated Case Reports in Gastroenterol 1995; 2: 5-10 174. A pregnant woman with a rapidly growing breast lump Khoo US, Chow LWC, Ho LWC, Tam R, Alagaratnam TT, Cheung ANY Hong Kong Med J 1995; 1: 253-257 175. Free perforation of gastric carcinoma: results of surgical treatment Gertsch P, Yip SKH, Chow LWC, Lauder IJ Arch Surg 1995; 130: 177-181 176. Efficacy of leucocyte count and neutrophil percentage in the clinical diagnosis of acute appendicitis Chow LWC, Loh TKS, Ong CL, Png DJC Asian J Surg 1994; 17: 49-52 22 Chow L.W.C. 177. Retroperitoneal perforation complicating through -the-scope pyloric dilatation Chow LWC, Ong CL Gastrointest Endosc 1994; 40: 122-123 178. Fournier’s gangrene Chow LWC, Ong CL, Png DJC, Loh TKS, Rajagopalan R Br J Clin Pract 1993; 47: 277-278 179. Gallbladder empyema – another good reason for early cholecystectomy Chow WC, Ong CL, Png DJC, Rauff A J R Coll Surg Edinb 1993; 38: 213-215 180. Massive per rectal bleeding from an ulceration in a jejunal diverticulum Chow LWC, Ong CL, Png DJC J Clin Gastroenterol 1993; 17: 85-86 181. Role of sequential leucocyte counts and c-reactive protein measurements in acute appendicitis Chow LWC, Loh TKS, Ong CL Brit J Surg 1993; 80: 673 182. Necrotizing fasciitis revisited Chow LWC, Ong CL, Png DJC, Loh TKS, Rajagopalan R Contemp Surg 1993; 42: 181-184 183. Percutaneous fine needle aspiration cytology for solid pulmonary lesions Chow WC, Yip WC, Cheng CS, Lam HS, Chan NK, Gwi E, Nandi PL Asian J Surg 1993; 16: 67-70 184. Technical modification to laparoscopic appendectomy Goh P, Tekant Y, Kum CK, Chow L, Ngoi SS Dis Colon and Rectum 1992; 35: 999-1000 185. Intracranial meningioma with metastatic breast carcinoma Chow WC, Ho KH, Fong CM Ann Oncol 1992; 3: 409-410 186. Mirrzi syndrome with cholecystocholedochal fistula: preoperative diagnosis and management Yip WC, Chow WC, Chan J, Lam KH Surgery 1992; 111: 335-338 187. Tension pneumoperitoneum after colonoscopic polypectomy Yip WC, Chow WC, Chan J Endoscopy 1991; 23: 241 188. Plea for selective operative cholangiography Yip WC, Ng WS, Chow WC, Choi TK, Lam KH J R Coll Surg Edinb 1991; 36: 21-24 189. Interpostion drafting for femoral venous injury Nandi PL, Chow WC, Yip WC Asian J Surg 1990; 13: 222-225 190. Removal of intrahepatic stone Ng SK, Yip WC, Chow WC, Choi TK Gastrointest Endosc 1990; 36: 402-404 23 Chow L.W.C. Book Chapter 1. Chow LWC. Combination Anti-aromatase therapy. In “Anti-Aromatase therapy for Breast Cancer - New Developments”. Sasano H and Toi M Eds. Ch5; pp227 -235 2. 周永昌, 鲁慶榮. 實用乳腺病學. In “国际乳腺癌临床研究现状及展望 Practice of Breast Diseases”. 崔维奇, 雷秋模, 左文迷, 张凤春, 漆幼珊, 彭成华. Ch1; pp5-24 Patent A mouse cell line derived from human malignant cystosarcoma phylloides Prizes 1. 第七届全国乳腺癌重庆论坛, Chongqing, China, December 21-23, 2012 (中华医学会金显宅乳腺癌研究纪念奖 / Kim Hyun-Jib Breast Cancer Research Memorial Award) 2. Cyclooxygenase-2: Possible Predictor Related to Micro -metastasis in Breast Cancer Patients Zhu L, Chow LWC 1st Annual Scientific Conference, Organisation for Oncology and Translational Research, October 2004, Hong Kong (Young Investigator Award) The Correlation of Tumor Markers CEA and CA15.3 with the extent of breast cancer using 18-flouro-2-deoxy-D-glucose positron emission tomography 18 ( FDG-PET) Kwong AK, Cheng CW, Yeung D, Lam CK, Chow LWC Annual Congress, Asian Surgical Association, Kota Kinabalu, December 2003 (1st prize award for poster) 3. 4. The use of Nottingham Prognostic index and c -erb-B2 status as prognostic indicators of Chinese breast can cer Kwong A, Chow LWC 1st Roche Asia Oncology Forum, Shanghai, China, September 2002 (1st prize award) Research Supervision Experience 1. Supervision of Ph.D. Student Dr XC Hu: Detection of micrometastasis of breast cancer by RT -PCR 2. Supervision of M MedSci Student Dr Chung Pui Yi, Rebecca: Breast care module 3. Supervision of MPhil Student Dr Zhu Li: Detection of bone micrometastasis from breast cancer 4. Supervision of MMedSci Student Mr Eric Lui: TBC Examiners for Postgraduate Examinations 1. Internal Examiner for Dr K.C. Ng, Ph D Candidate, The University of Hong Kong, 2004 Local and systemic effects of hepatic radiofrequency ablation in animal models 24 Chow L.W.C. 2. Additional Examiner for Professor ST Fan, PhD Candidate, The University of Hong Kong, 2003 Adult-to-adult live donor liver transplantation using right lobe graft 3. Internal Examiner for Ms Leung Wai Ching Wa, Gina, PhD candidate, The University of Hong Kong, 2002 The influence of flutamide, tamoxifen and dietary fat on hormone-induced mammary carcinogenesis 4. Internal Examiner for Ms Mable Wu, MMedSci candidate, The University of Hong Kong, 2002 5. Internal Examiner for Mr Xi Chun Hu, PhD candidate, The University of Hong Kong, 2001 Study on the Use of Potential Prognostic Parameters in Breast Cancer Patients International Research Collaboration Project Tumour invasion and histoculture drug response assay (HDRA) Collaborator Dr Robert M. Hoffman President, AntiCancer Inc, San Diego and Professor, Department of Surgery, University of California, San Diego Project Collaborator Changes in angiogenesis markers after neoadjuvant treatment of breast cancer Dr Masakazu Toi Director, Department of Surgery, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan Research/Professional Grants Awarded 1. Chemosensitivity Testing Service for Selection of Chemotherapy in Breast Cancer Patients (Project no.: 204217) 2. 3. Source: SK Yee Medical Foundation Grant 2004 Amount: HK$1,158,753.20 The effects of psychosocial intervention on the psychosocial and neuroendocrine outcomes: a prospective 3-group randomised trial with Chinese breast cancer patients (as co-investigator) Source: RGC Competitive Earmarked Research Grant Award 2003 -2004 Amount: HK$282,100 Radioguided Surgery and Breast Cancer Management Course and Seminars (Ref: 2002-2-27) 4. Source: Professional Services Development and Assistance Scheme 2003 Duration: 2002-2004 Amount: HK$249,000 Status: stat Project completed Source: CRCG Research Grant Duration: September 2002 to April 2004 Amount: HK$120,000 Status: stat Project completed Methylation changes during longitudinal follow-up of breast cancer patients 25 Chow L.W.C. 5. Collaborative Laboratory Research on KY88 Liver Livo Source: Innovation and Technology Fund; University -Industry Collaboration Programme Duration: April 2000 to March 2002 Amount: HK$ 670,000 Status: stat Publications Project completed i. Chow LWC, Loo WTY, Sham JST. Effects of Bupleurum containing herbal compound on human lymphocytes. Hong Kong Med J. 2001; 7: 408-413 ii. Chow LWC, Loo WTY, Sham JST, et al. Radix bupleuri containing compound (KY88 liverlivo) induces apoptosis and production of interleukin-4 and tumor necrosis factor-α in liver cancer cells in vitro. Am J Chin Med. 2004; 32: 185-193 iii. Chow WCL, Loo TY, Sham STJ Cytokine production by human lymphocytes stimulated by a herbal compound containing Bupleurum (KY88 LIVER LIVO). Acta Pharmacol Sinica 2003; 24: 140-144 Donations A total of HK$2,500,000 was donated from personal/company accounts to the Division of Breast Surgery for research purposes Applied/Translational Research Co-investigator of International Clinical Trials (as listed in Clinical Trials Centre of HKU) Protocol HERA: A randomised three-arm multi-centre comparison of 1 year and 2 years of Herceptin® versus no Herceptin® in women with HER2 -positive primary breast cancer who have completed adjuvant chemotherapy Protocol No.: BIG01-01/BO16348B, Sponsored by Roche Remarks: Completed patient enrolment Protocol A multicenter phase III randomized trial comparing Docetaxel in combination with Doxorubicin and Cyclophosphamide (TAC) versus Doxorubicin and Cyclophosphamide followed by Docetaxel (AC T) as adjuvant treatment of operable breast cancer HER2/neu negative patients with positive axillary lymph nodes. BCIRG 005 Protocol No.: BCIRG 005, Sponsored by Adventis Remarks: Completed patient enrolment Protocol Multicenter Phase III Randomized Trial Comparing Doxorubicin and Cyclophosphamide followed by Docetaxel (ACT) with Doxorubicin and Cyclophosphamide followed by Docetaxel and Trastuzumab (Herceptin®) (ACTH) and with Docetaxel, Carboplatin and Trastuzumab (TCH) in the Adjuvant Treatment of Node Positive and High Risk Node Negative Patients with Operable Breast Cancer containing the HER2 Alteration Protocol No.: BCIRG 006, Sponsored by Adventis Remarks: Completed patient enrolment Protocol Amonafide: Individual phenotype-adjusted chemotherapy for women with metastatic breast cancer who have progressed despite prior chemotherapy Protocol No.: 0001A1-200-GL, Sponsored by Xanthus, CRO: Orion Remarks: Completed patient enrolment Protocol An Open-Label, Randomized, Multicenter Study to Evaluate the Use of Zoledronic Acid in the Prevention of Cancer Treatment -Related Bone Loss in Postmenopausal Women with ER+ and/or PgR+Breast Cancer Receiving Letrozole as Adjuvant Therapy Protocol No.: CFEM345D2405, Sponsored by Novartis 26 Chow L.W.C. Protocol A Phase II, Open-Label, Randomized, Parallel-Group Multicenter Trial Comparing Two Schedules of GW572016 as First -Line Monotherapy in Patients with Advanced or Metastatic Breast Cancer. Protocol No.: EGF 20009, Sponsored by GSK Remarks: Completed patient enrolment Principal Investigator of International Clinical Trials 1. Prospective Randomized Celebrex Anti -Aromatase Neoadjuvant (CAAN) trial on Locally Advanced Breast Cancer 2. Phase II Study on the Neoadjuvant Use of Chemotherapy and Celecoxib Therapy in Patients with Invasive Breast Cancer 3. Evaluation of the Neoadjuvant Inhibition of Armoatase Activity and Signal Transduction in Breast Cancer: The Femara/Glivec Study 4. Randomized Trial of Docetaxel (T) with or without Capecitabine (X) as Neoadjuvant Chemotherapy in Female Patients with Operable Breast Cancer Who were not Observed Disease Progression after 4 cycles of 5-Fluorouracil, Epirubicin and Cyclophosphamide (FEC) Editorial Board Membership 1. Member, International Editorial Committee, The Journal of Breast Cancer 2. Member, Editorial Board, Chinese Journal of Surgical Therapy 3. Member, Editorial Board, BMJ (Chinese) 4. Member, Editorial Board, Update in Breast Cancer Therapy 5. Guest Editor, Breast Cancer Symposium Asian Journal of Surgery 6. Member of Editorial Board, The Chinese Journal of Surgical Oncology February 2004 – present 7. Corresponding Editor, Chinese Medical Journal (Beijing) Chinese Medical Association, China, June 2000 to present 8. Editor, Faculty Newsletter Faculty of Medicine, University of Hong Kong, April 2000 to present Guest Editor Symposium on Sentinel Lymph Node Biopsy, October Issue, 2004, Asian Journal of Surgery Journal Reviewer 1. Annals of Hong Kong College of Surgeons 2. Hong Kong Medical Journal 3. Asian Journal of Surgery 27 Chow L.W.C. 4. Journal of Pharmacology and Experimental Therapeutics 5. Clinical Cancer Research 6. Journal of Clinical Chemistry 7. International Immunopharmacology 8. Journal Biologia, Bratislava 9. Journal of Breast Cancer (External Peer Reviewer) 10. Chinese Journal of Traditional and Western Medicine (Executive Chief Editor) 11. Cancer Epidemiology, Biomarkers & Prevention (External Reviewer) 12. Journal of Cancer Research and Therapeutics (External Reviewer) 13. Annals of Oncology (External Reviewer) Invited / Plenary Lectures 1. 乳腺癌手术:实践与研究 2013 年西南医院乳腺外科学术年会, Chongqing, China, December 14, 2013 2. 乳腺癌的治疗 第 一 届 深 港 肿 瘤 防 治 论 坛 暨 深 圳 市 抗 癌 协 会 学 术 年 会 , Shenzhen, China, December 7, 2013 3. 乳腺癌轉化研究之晚期乳腺癌復發、轉移治療方法 第五屆江西乳腺疾病高層論壇, Jiangxi, China, November 22-23, 2013 4. Refining Clinical Approach to HER2 -Positive Early Breast Cancer Roche Korea Breast Cancer Forum, Gwangju, Korea, October 26-27, 2013 5. The role of mTOR inhibitors in the management of advanced breast cancer Philippines Breast Cancer Society Meeting, Manila, Philippines, October 23 -24, 2013 6. Understanding Intratumor Heterogeneity 第 十 六 届 全 国 临 床 肿 瘤 学 大 会 暨 2013 年 CSCO 学 术 年 会 , Xiamen, China, September 25-29, 2013 7. 乳腺癌肿瘤异质性 第五届全国乳腺微创外科大会, Chongqing, China, September 13-16, 2013 8. 早期乳腺癌的分子诊断与治疗 中国乳腺病论坛, Beijing, China, September 13-15, 2013 9. 香港年轻乳腺癌治疗现状 中国年轻乳腺癌南北高峰论坛, Wuyishan, China, August 10-11, 2013 10. 复发转移乳腺癌的治疗进展 甲状腺、乳腺疾病诊治新视觉学习班, Shenzhen, China, August 2, 2013 11. New Strategies for an Evolving Disease Breast Cancer Tour, Beijing & Shanghai, June 22-23, 2013 28 Chow L.W.C. 12. 乳腺癌个体化治疗的发展及挑战 第二届海峡乳腺论坛暨第四届福建省乳腺论坛, Xiamen, China, June 15-16, 2013 13. How could we select patients for IORT after B reast Conservation Surgery IORT in Breast Cancer Symposium, Hong Kong, China, May 27, 2013 14. The Feasibility of IORT for Asian Breast Cancer Patients with Median Size Breasts (Indications of IORT in Asian Breast Cancer Patients) New Frontier in Breast Cancer Surgery - Trans-Asia Symposium of IntraOperative Radiotherapy & Surgical Techniques, Taipei, Taiwan, May 25, 2013 15. Achieving Best Outcome of Conserving Breast Surgery New Frontier in Breast Cancer Surgery - Trans-Asia Symposium of IntraOperative Radiotherapy & Surgical Techniques, Taipei, Taiwan, May 25, 2013 16. HER2 陽性乳腺癌治療新進展 Macau Oncology Association Exchange Symposium, Macau, China, May 18, 2013 17. 乳腺癌治疗新突破 第 5 届广东乳腺病研讨会, Guangzhou, China, May 17-18, 2013 18. A multimodality approach to neoadjuvant therapy for breast cancer The 9th Annual Conference of the Organisation for Oncology and Translational Research (OOTR) in conjunction with The Asian Oncology Summit (AOS) 2013, Bangkok, Thailand, March 22-24, 2013 19. Racial differences in breast cancer treatment The 9th Annual Conference of the Organisation for Oncology and Translational Research (OOTR) in conjunction with The Asian Oncology Summit (AOS) 2013, Bangkok, Thailand, March 22-24, 2013 20. 从临床获益向乳腺癌个体化治疗的转变 The 5th Harbin Breast Cancer Forum, Harbin, China, January 5, 2013 21. 乳腺癌手术治疗之最新进展 第七届全国乳腺癌重庆论坛, Chongqing, China, December 21-23, 2012 22. 崭新靶向药物治疗耐药性乳腺癌 第五届粤港澳肿瘤大会暨第九届全国肿瘤综合治疗新进班, Zhongshan, China, October 13-14, 2012 23. 乳腺癌外科的微创理念与进展 第三屆中國腫瘤外科微創學術研討會, Yinchuna, China, September 28-30, 2012 24. What is Adequate Margin in Chinese Small or Medium Size Breast 2012 Taipei International Breast Cancer Symposium (TIBCS), Taipei, Taiwan, September 21-23, 2012 25. 具抗药性乳腺癌病人的组合性用药治疗方案及其疗效和监察的探讨 The 15th Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Beijing, China, September 19-23, 2012 26. 探讨具抗药性乳腺癌病人临床组合性药物治疗的新方案及疗效的监察 江西南昌国际论坛, Nanchang, China, September 7-9, 2012 27. Basal Subtype Breast Cancer - Therapeutic Implication 10th Asian Breast Diseases Association (ABDA) Teaching Course and Workshop, Hong Kong, June 22-24, 2012 28. Personalized Medicine in Breast Cancer 10th International Conference of Asian Clinical Oncology Society (ACOS), Seoul, Korea, June 13-15, 2012 29 Chow L.W.C. 29. Prevention of oncological diseases th The 8 Annual Conference of Organisation for Oncology and Translational Research (OOTR), Kyoto, Japan, April 20 -21, 2012 30. Research into new targeting agents Asian Oncology Summit (AOS) 2012, Singapore, April 13-15, 2012 31. Prospective strategies to treat drug resistant cancers Asian Oncology Summit (AOS) 2012, Singapore, April 13 -15, 2012 32. 乳腺癌的术前治疗策略 Chang Gung Memorial Hospital Breast Cancer Conference 2011, Taipei, Taiwan, December 17, 2011 33. Private Health Care Sector as an Alternative Study Site Provider Clinical Trial Magnifier Conference 2011, Taipei, Taiwan, November 18 -20, 2011 34. Current Status and Clinical Development of BC Stream APECHO-LEAD Summit, Seoul, Korea, October 28-29, 2011 35. Year in review in Asia 49th Annual Meeting of the Japanese Society of Clinical Oncology (JSCO), Aichi, Japan, October 27-29, 2011 36. 乳腺癌的术前治疗策略 恶性肿瘤诊治新进展专题讨论会, Shenzhen, China, October 2 - 5, 2011 37. 乳腺癌新辅助治疗与耐药机制的探索 第四届全国乳腺微创治疗研讨会, Chongqing, China, September 23 – 26, 2011 38. 个体化新辅助治疗和辅助手段的应用 The 14th Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Xiamen, China, September 14 – 18, 2011 39. Breast Cancer Therapy 9th Asia Pacific Oncology Summit (APOS), Bangkok, Thailand, August 19 – 20, 2011 40. Personalizing Neoadjuvant Therapy and Applications Toward Adjuvant Approaches Asian Pacific Oncology Conference (APOC), Nanjing, China, July 15 – 17, 2011 41. 内分泌药物治疗对绝经后乳腺癌病人骨质疏松的影响 中国抗癌协会乳腺癌诊治指南与规范(2011 版)全国巡讲(江西站)暨第三届 江西乳腺疾病高层论坛, Nanchang, China, July 2 – 3, 2011 42. Optimal use and future perspective of neoadjuvant therapy in breast cancer Kyoto Breast Cancer Consensus Conference (KBCCC), Kyoto, Japan, April 14 – 16, 2011 43. Expectations with Expertise: Practical Management Forum Asian Oncology Summit (AOS) 2011, Hong Kong, April 8 – 10, 2011 44. Application of biomarkers to sentinel lymph node biopsy for the management of breast cancer Asian Oncology Summit (AOS) 2011, Hong Kong, April 8 – 10, 2011 45. Hormone therapy for metastatic breast cancer Asian Oncology Summit (AOS) 2011, Hong Kong, April 8 - 10 2011 46. Breast Reconstruction after Breast Conservative Surgery with Autologous Tissue 3rd International Oncoplastic Breast Surgery Symposium, Tokyo, Japan, November 25 – 26, 2010 30 Chow L.W.C. 47. 初期乳癌的診斷方法 第二届粵港澳檢驗醫學學術大會檢驗新進展國際研討會, Macau, November 5 -7, 2010 48. Inter-disciplinary Expert Panel Discussion II N.O.T.E.S. - Chairman 2nd World (20th Chinese) Endoscopy Doctors Conference & 2nd Macau-Hong Kong Surgical Scientific Meeting, Macau, October 29 – November 1, 2010 49. 國際乳腺癌臨床研究現狀和展望 第六届全国乳腺癌重庆论坛, Chongqing, China, September 24 – 26, 2010 50. 转化性研究与个人化治疗 The 13th Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Beijing, China, September 16 – 19, 2010 51. Update Adjuvant Chemotherapy Focus on Triple -Negative Breast Cancer Taipei International Breast Cancer Symposium, Taiwan, September 3 – 5, 2010 52. Global and Asian consensus in breast cancer managements – case presenter 9th International Conference of The Asian Clinical Oncology Society (ACOS), Gifu, Japan, August 25 – 27, 2010 53. Do we need to perform lymphadenectomy if sentinel node is positive? UICC World Cancer Congress, Shenzhen, China , August 18 – 21, 2010 54. Investigator Breast Cancer Trial Network in China and Asia Clinical Trial Magnifier 2009 Conference (CTC), Hong Kong, November 13-15, 2009 55. General Situation of Breast Cancer and Screening in Hong Kong and Macao The Second Asia Pacific Health Symposium, Tainan, Taiwan, November 8, 2009 56. 乳腺癌 HER2 信号传导研究进展 The 12th Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Xiamen, China, October 2009 57. 乳腺癌新辅助化疗 th The 12 Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Xiamen, China, October 2009 58. Towards Anthracycline-free in Adjuvant Setting th Global Breast Cancer Conference 2009 with the 7 Biennial Meeting of the Asian Breast Cancer Society (ABCS), Seoul, Korea, October 2009 59. Introduction of Breast Cancer Breast Cancer Nurse Workshop, St. Teresa Hospital, Hong Kong, September 2009 60. Breast Cancer Treatment Developments by Clinical Trials in Asia International Surgical Week 2009, Adelaide, Australia, September 2009 61. Progress in Preoperative Therapy in Breast Cancer nd The 2 International Symposium on the Prevention of Breast Cancers, Taiwan, August 2009 62. 乳癌近十年之治療進展 癌症治療講座, Hong Kong, July 2009 31 Chow L.W.C. 63. Insights Into Evolving Breast Cancer Practice Patterns in China Breast Cancer Congress, Maui, Hawaii, United States of America, July 2009 64. Progress in Preoperative Therapy Breast Cancer Congress, Maui, Hawaii, United States of America, July 2009 65. 亚洲乳腺癌筛查现状 早期诊断专题研討會, Shenzhen, China, July 2009 66. Network Formation for Sharing of Clinical Data 2009 년 한국유방암학회 춘계학술대회, Jeju, Korea, June 2009 67. Breast Cancer Screening – Biofield Diagnostic System Manila, April 2009 68. Sentinel Lymph Node Biopsy: Before or After Preoperative Chemotherapy Asian Oncology Summit (AOS), Singapore, April 2009 69. Surgeon’s Consideration of Image Guided Biopsy for Impalpable Breast Lesions Taiwan, April 2009 70. New Trials and Chemoprevention in Asia th 5 Annual Scientific Conference of Organisation for Oncology and Translational Research, Macau SAR, February 2009 71. Multidisciplinary Management of Early Breast Cancer in China: Current Challenges th 5 Annual Scientific Conference of Organisation for Oncology and Translational Research, Macau SAR, February 2009 72. Bevacizumab: A Blend into Traditional Chemotherapy with Translational Research th 7 Roche Asia Oncology Forum 2008, Bangkok, November 2008 73. 香港乳腺癌篩查和早期診斷的經驗 早期乳腺癌研討會, Shenzhen, China, November 2008 74. Case Presentation th The 6 Asia Pacific Oncology Summit, Xian, October 2008 75. Make Right Decisions for Patients – The Progress on The Hormonal Therapy in Breast Cancer AstraZeneca satellite meeting, Shanghai, China, Oct ober 2008 76. Satellite Symposium – Breast Cancer Surgery th 15 World Congress on breast disease, Shanghai, October 2008 77. Neoadjuvant Trials in Asia th 15 World Congress on beast disease Shanghai, October 2008 78. A New Era of Hormonal Therapy in Breast Cancer Treatment IX International Aromatase Conference, Shanghai, Oct ober 2008 79. 國際乳腺癌治療新動態 2008 第五屆乳腺癌重慶論壇, Chongqing, China, October 2008 80. Neoadjuvant Hormonal Therapy for Breast Cancer 2008 廣 州 乳 腺 癌 臨 床 診 治 論 壇 暨 第 二 屆 中 大 一 哈 佛 乳 腺 癌 學 術 研 討 會 , Guangzhou, September 2008 32 Chow L.W.C. 81. 賀爾蒙週期變化與乳腺癌的關係 Macau, September 2008 82. Tailoring and expanding the role of erbB2 targeted agents in breast cancer Annual meeting of the Taiwan Breast Cancer Society, Taipei, September 2008 83. Future Potential of ErbB2 Targeted Therapy in Early BC Chinese Society of Clinical Oncology Annual Meeting, Shanghai, Aug ust 2008 84. Satellite Symposium th The 9 Annual conference of Korean Breast Cancer Society, South Korea, June 2008 85. Overview of targeted therapy in breast cancer 國際乳腺癌臨床及病理診斷及治療標準化研討會, 中國銀川, 5 月 2008 年 86. International clinical practice guidelines for breast cancer 國際乳腺癌臨床及病理診斷及治療標準化研討會, 中國銀川, 5 月 2008 年 87. Current Treatment of Locally Advanced Breast Cancer in the Asia-Pacific Region, Including Neoadjuvent Therapy – Challenges and Limitations Scientific and Clinical Expert Panel Meeting, Singapore, March 2008 88. Tyrosine Kinase Inhibitors in Breast Cancer – Current Experience and Future Perspectives st Industry Satellite Symposium, 1 Asian Breast Cancer Congress, India, February 2008 89. Breast Cancer Management in Hong Kong 21 世紀亞太乳房健康管理研討會, December 2007 90. Lapatinib as A First-line Treatment in Patients with ErbB2 Positive Advanced or Metastatic Breast Cancer and Biomarkers Analysis Global Breast Cancer Conference, October 2007 91. Neoadjuvant Hormonal Therapy for Breast Cancer Global Breast Cancer Conference, October 2007 92. Clinical Trial in Asian th 6 Asian Breast Cancer Conference, September 2007 93. 乳腺癌手術治療新進展 澳門腫瘤醫學會第二屆學術年會, Macau, September 2007 94. 乳癌之外物及藥物治療 澳門中華醫學會持續醫學教育課程, Macau, September 2007 95. Timing and Translational aspects in Trastuzumab therapy th 6 Roche Asian Oncology Forum (RAOF), Malaysia, August 2007 96. 乳腺癌生物靶向治療 2007 中國普外科焦點問題學術論壇, China, August 2007 97. Phase 3 Study of Temsirolimus with Letrozole or Letrozole Alone in Postmenopausal Women with Locally Advanced or Metastatic Breast Cancer Sendai, Japan, February 2007 98. Lapatinib Single Agent in First line Metastatic Breast Cancer Asiapac Breast Cancer Experts Meeting, Singapore November 2006 33 Chow L.W.C. 99. Future Directions : Clinical Research and New Medicine for Women ’s Cancer Beijing Women’s Health Summit, Beijing, China, November 2006 100. Creating New Strategies for Cancer Therapy and Prevention nd 2 Annual Conference of the Organisation for Oncology and Translational Research, Tokyo, Japan, November 2005 101. Paradigm Shift in The Management of Breast Cancer Special Lecture, Shanghai Cancer Hospital, Shanghai, China, October 2004 102. Clinical Experience on COX-2 Inhibition in Breast Cancer st 1 Annual Conference, Organisation for Oncology and Translational Research Hong Kong, October 2004 103. Keynote Lecture: Current Direction of COX -2 Inhibition in Breast Cancer Second Asia Pacific Oncology Summit: Commitment to Advancing the Treatment of Solid Tumors, Suzhou, China, October 2004 104. New Paradigm in the Treatment of Breast Cancer 2004 National Congress on the Diagnosis and Management of Breast Cancer The Breast Society of the Chinese Medical Association , Chongqing, China, September 2004 105. Neoadjuvant Therapy for Breast Cancer Tohoku University Faculty of Medicine, Sendai, Japan, July 2004 106. Neoadjuvant Therapy for Breast Cancer Inaugural Stanford-Hong Kong Oncology Teleconference and Seminar – Update in Breast Cancer Investigation and Treatment , Hong Kong, April 2004 107. Neoadjuvant Hormonal Therapy Key Advances in the Treatment of Breast Cancer, Hong Kong, February 2004 108. Clinical Management of Women with BRCA1 or BRCA2 Asian Breast Cancer Conference, Taipei, February 2004 109. To Screen or Not To Screen: The Evidences th 10 Hong Kong International Cancer Congress, Hong Kong, November 2003 110. Stereotatic Breast Biopsy with Vacuum Assisted Minimally Invasive Biopsy Technology First Mammotome Asia Pacific Summit Meeting, Shanghai, China November 2003 111. Celecoxib Anti-aromatase Neoadjuvant (CAAN) Trial for Locally Advanced Breast Cancer: Preliminary Report First Asia Pacific Oncology Summit, Hanoi, China, October 2003 112. Phase II Study on An “All-oral” Regimen of Capecitabine, Idarubicin and Cyclophosphamide in Metastatic Breast Cancer; -Possibility and EfficacyThe 2nd Roche Asia Oncology Forum, Taipei, October 2003 113. Introduction to Breast Mapping Radioguided Breast Cancer Surgery Symposium, The Breast Cancer Society of Taiwan, November 2002 34 Chow L.W.C. 114. Celebrex Anti-aromatase Neoadjuvant Trial for Locally Advanced Breast Cancer VI International Aromatase Conference - Aromatase 2002: The new millennium, Kyoto, October 2002 115. All-oral Combination Therapy and Practical Patient Management with Xeloda st 1 Roche Asia Oncology Symposium, Shanghai, China, September 2002 116. Current Treatment of Breast Cancer Making the Difference in the Management of Breast Cancer, Pharmacia Symposium, Xian, China, June 2002 117. Radioguided Surgery for Breast Cancer Chinese Medical Association, Breast Cancer Group, Beijing, China, March 2002 118. Sentinel Biopsy for Breast Cancer Hong Kong Surgical Forum, Hong Kong, January 2002 119. Sentinel Biopsy for Breast Cancer Eight Joint Shanghai/Hong Kong Surgical Convention, Shanghai, January 2002 120. Breast Cancer in Hong Kong th The 5 Symposium of the Shanghai Anti-Cancer Association, Yangzhou, November 2001 121. Locally Advanced Breast Cancer th The 13 Biennial Congress of the Asian Surgical Association, Singapore, November 2001 122. Sentinel Lymph Node Biopsy in Breast Cancer Management th 8 Hong Kong International Cancer Congress, Hong Kong, September 2001 123. Debate on Breast Cancer Screening th 8 Hong Kong International Cancer Congress, Hong Kong, September 2001 124. Sentinel Lymph Node Biopsy in BC Management – Theory and Practice st 1 Meeting of the Chinese Breast Cancer Society, Chongqing, China, September 2001 125. Management of Breast Cancer Hong Kong Medical Association CME Program 2001, , Hong Kong, July 2001 126. The Epidemiology of Breast Cancer in Hong Kong rd The 3 Biennial Meeting of the Asian Breast Cancer Society, Seoul, Korea, June 2001 127. Epirubicin-Based Neoadjuvant and Adjuvant Treatment of Breast Cancer th 5 International Conference of the Asian Clinical Oncology Society & the 6th Taiwan Joint Cancer Conference, Taipei, April 2001 128. Management of Impalpable Breast Cancer nd The 2 Cross-Strait & World Chinese General Surgical Congress, Chinese Surgical Society, Wuhan, China, November 2000 129. Management of Locally Advanced Breast Cancer in Hong Kong Taipei International Breast Cancer Symposium, Taipei, October 2000 130. Breast Cancer Screening – an Overview Symposium on Molecular Medicine for the Practising Clinicians, Centre of Endocrinology & Diabetes, University of Hong Kong, May 2000 35 Chow L.W.C. 131. Local Experience in the Use of Xeloda in the Management of Metastatic Breast Cancer Scientific Symposium, Hong Kong Anticancer Society, April 2000 132. Tamoxifen in Prevention of Breast Cancer th 6 Hong Kong International Cancer Congress, November 1999 133. Breast Conservation Surgery th 6 Hong Kong International Cancer Congress, November 1999 134. Mechanism of Actions of TCM: Laboratory Studies th 6 Hong Kong International Cancer Congress, November 1999 135. Tumour Markers in the Management of Breast Cancer th 12 Biennial Congress, Asian Surgical Association and Royal Australasian College of Surgeons, Brisbane, Australia, March 1999 136. Critical Evaluation and Practical Application of Prognostic Factors Advanced Workshop in Breast Cancer Management, European School of Oncology and Kwong Wah Hospital, Hong Kong, November 1998 137. The effect of Polysaccharide Peptide (PSP) in breast cancer Symposium on Advances in Traditional Chinese Medicine, University of Hong Kong, June 1998 138. Application of Chemosensitivity Testing in Breast Cancer th th 14 Asian Pacific Cancer Congress and 4 Hong Kong International Cancer Congress, Hong Kong, November 1997 139. Management of Ductal Carcinoma In-Situ th th 14 Asian Pacific Cancer Congress and 4 Hong Kong International Cancer Congress, Hong Kong, November 1997 140. Prognostic Factors of Breast Cancer th 110 Anniversary & Medical Congress, University of Hong Kong, Hong Kong, October 1997 141. Predictors of Response of Breast Cancer th 11 Biennial Congress, Asian Surgical Association, Hong Kong, March 1997 142. The Management of Recurrent Breast Cancer th 11 Biennial Congress, Asian Surgical Association, Hong Kong, March 1997 143. Surgical Treatment of Invasive Breast Cancer in Hon g Kong Breast Cancer Symposium, 16th Annual Meeting, Chinese Medical Association, Taiwan, June 1996 144. Treatment of Breast Cancer in Hong Kong Japanese Breast Cancer Society, Osaka, 1996 145. Use of Prognostic Factors in Patient Management - Clinician’s Point of View Workshop on Breast Diseases, Hong Kong Pathology Society, May 1995 146. Extent and Limits of Surgery - Breast Cancer Surgical Forum, The University of Hong Kong, July 1994 36