Measuring modulation transfer function of the Alcon
Transcription
Measuring modulation transfer function of the Alcon
www.eyeworld.org Achieving Success with Cataract and Refractive Technology The News Magazine of the American Society of Cataract & Refractive Surgery Supplement to EyeWorld June 2008 • Reprinted from the 2008 ASCRS Chicago Show Daily Supported by an unrestricted educational grant from Alcon, Inc. Measuring modulation transfer function of the Alcon aspheric apodized diffractive multifocal IOL and clinical outcomes phthalmologists are often concerned about contrast sensitivity among the elderly to ensure those patients can perform dayto-day tasks like walking down steps in low light conditions. Contrast sensitivity as measured by modulation transfer function looks at the quality of an image through the lens optics and really is the first step to achieving better contrast sensitivity. Clearly, modulation transfer function is better with the aspheric AcrySof ReSTOR IOL (Alcon, Fort Worth, Texas) compared with the standard ReSTOR lens, according to Jim Schwiegerling, Ph.D., Depart-ment of Ophthalmology & Vision Sciences, University of Arizona, Tucson. O An ETDRS letter chart imaged through an eye model (6-mm aperture) containing four different multifocal IOLs; the AcrySof ReSTOR aspheric IOL produces the highest quality image with the fewest stray light effects That means “patients will have slightly better contrast for distance vision, slightly sharper images, and fewer side effects especially at night in terms of halos and glare,” Dr. Schwiegerling said. “We see a bit of a distance boost with the Table of Contents Measuring modulation transfer function of the Alcon aspheric apodized diffractive multifocal IOL and clinical outcomes ............................1 ReSTOR aspheric, premium results for demanding patients ......................2 High energy blue light filtration: An evidence-based assessment ....................3 A new tool to analyze how much the cataract incision influences the refractive outcome ................................4 Early experience with the AcrySof Toric IOL ..................................5 Silo Scheduling: Proactive templates deliver the practice you desire ......................6 Are lifestyle IOLs worth it? Establishing realistic financial goals for upgraded lenses ............................7 aspheric design, without giving up anything to obtain it.” Dr. Schwiegerling’s study involved a benchtop test, with a model eye that has a simulated cornea with clinical levels of spherical aberration and chromatic aberration. The different IOLs were then inserted into the eye model, and the images were analyzed to objectively measure the different designs’ relative performance. The methodology is very standard, having been used over the last 20 years in modulation transfer function testing, he said. Dr. Schwiegerling noted that the standard ReSTOR lens design ignored the impact of spherical aberration on a patient’s vision while the ReSTOR aspheric design took it into account. “The aspheric design works in conjunction with the cornea to cancel out these aberrations,” Dr. Schwiegerling said. “That’s where the performance enhancement comes from.” The Tecnis MF (Advanced Medical Optics, AMO, Santa Ana, Calif.) lens is a similar design to the ReSTOR aspheric, as it has both aspheric and multifocal properties. “The advantage of the ReSTOR is that the apodized diffractive portion turns into a pure refractive lens in the periphery, and that tends to suppress halos and glare,” Dr. Schwiegerling said. “The Tecnis design’s diffractive nature goes all the way out to the periphery so for large pupils you get halos. The ReSTOR turns into a purely refractive lens in the periphery, so in comparison it reduces the out-offocus stray light. Asphericity alone is not enough to overcome the diffractive effects produced by the design of the Tecnis lens.” continued to page 7 “[With the ReSTOR aspheric] patients will have slightly better contrast for distance vision, slightly sharper images, and fewer side effects especially at night in terms of halos and glare.” Jim Schwiegerling, Ph.D. 2 Achieving Success with Cataract and Refractive Technology ReSTOR aspheric, premium results for demanding patients ret L. Fisher, M.D., in private practice, The Eye Center of North Florida, Panama City, Fla., began implanting patients with the AcrySof ReSTOR aspheric IOL (Alcon, Fort Worth, Texas) in April 2007, and since has found visual acuity, contrast sensitivity, and even intermediate vision to be exceedingly good. “Patient satisfaction was substantially better subjectively and objectively,” than with the standard AcrySof ReSTOR IOL, Dr. Fisher said. “The patients function much better.” Dr. Fisher performed a study of 33 patients implanted with the aspheric IOL and 35 patients with the standard ReSTOR lens. Average visual acuity for distance vision was 20/25 with the ReSTOR aspheric. For preferred reading distance (at near), it was 20/20. Intermediate vision was even a little better than 20/20. “That was in contrast to some of the published data, including what Alcon published themselves for Food and Drug Administration approval,” Dr. Fisher said. Dr. Fisher explained the difference in results by saying he measured patients in “more of a real-world way” at preferred near, rather than B “With the ReSTOR, because of the design and different steps and zones, it gives you the most light for the situation that you’re using, whether reading or distance.” Bret L. Fisher, M.D. Results Contrast sensitivity in normal subjects; compared to these patients, those implanted with the AcrySof ReSTOR aspheric IOL achieved nearly identical contrast sensitivity results using a phoropter. The ReSTOR has been criticized for yielding plenty of reading and distance vision, but not as much intermediate, Dr. Fisher said. “That is what was discussed, but it was never really clinically experienced,” Dr. Fisher said. “When I look at my patients, [intermediate] is very good.” Contrast sensitivity results clearly set the ReSTOR aspheric IOL ahead of the standard one. When asked how satisfied they are with vision after surgery, on a scale from 0 to 10 (10 being most satisfied), ReSTOR aspheric patients scored their vision a 9, while standard ReSTOR patients gave their vision a 7.5. Further, Dr. Fisher said in photopic conditions, aspheric patients performed as well as agematched controls with healthy eyes in another study. “Even though this is a multifocal implant and you can expect some loss of contrast sensitivity, the results are virtually identical between ReSTOR aspheric patients and patients with the natural crystalline lens,” Dr. Fisher said. One sizable concern related to multifocal lenses has been the potential loss of contrast sensitivity. “When you’re taking light and splitting it to different focus points, that process is not 100% effective,” Dr. Fisher said. “If you lose light transfer in the process, you lose contrast sensitivity. But with the ReSTOR aspheric, because of the design, it gives you the most light for the situation that you’re using, whether reading or distance.” Now, Dr. Fisher uses the ReSTOR aspheric as the lens of choice on any cataract patient who wants to be less dependent on glasses. He said he achieved a rate of 87.5% spectacle independence with the ReSTOR aspheric. “There’s not another lens on the market that I’m aware of that can show this type of consistency,” Dr. Fisher said. Dr. Fisher said the AcrySof ReSTOR aspheric IOL provides surgeons with added benefits as well. “The designers of the implant were able to move to a proprietary biconvex shape, which makes the effective lens position more constant across the entire dioptric range of the lens. This can also improve predictability in calculating implant power and achieving the desired refractive outcome.” The excellent contrast sensitivity results are a “nice confirmation that the underlying technology in the lens really does work,” Dr. Fisher said. “We’re not seeing a degradation of contrast sensitivity compared to normal individuals.” Dr. Fisher has no financial interests related to this supplement. He can be contacted at 850-784-3937 or bfisher@eyecarenow. com. Results Of AcrySof ReSTOR aspheric IOL patients, 87.5% achieve spectacle independence Source: Bret L. Fisher, M.D. Achieving Success with Cataract and Refractive Technology 3 High energy blue light filtration: An evidence-based assessment nnovations in IOLs are seemingly endless. Whether you chart the progress from monofocal to multifocal technology or silicone to acrylic material, we live in a world in which cataract patients are better off today than yesterday. Without a doubt, that progress continues with adding a protective chromophore to the lens to achieve wonderful health benefits, according to Miguel N. Burnier Jr., M.D., professor of ophthalmology, pathology, medicine, and oncology, McGill University, Montreal, Canada. I “Yellow is the gold standard,” Dr. Burnier said. Yellow is the color that prevents blue light toxicity and concomitant problems, he said. If cataract patients don’t get a yellow lens, such as the AcrySof IQ IOL (Alcon, Fort Worth, Texas) or the AcrySof Natural IOL (Alcon), their eye health – and much more – is in jeopardy, Dr. Burnier said. “Over the lifetime of each patient, the retinal pigment epithelium [RPE] accumulates the fluorescent material called lipofuscin,” Dr. Burnier explained. “Blue light absorption by the lipofuscin IOL Monofocal Technology Advances 1949 PMMA 1983 SILICONE 2005 + 1994 HYDROPHOBIC ACRYLIC Aspheric Optic UV only UV and Blue Light Filtering Sir Harold Ridley UV and blue light filtering IOLs (pictured above), like the AcrySof Natural and AcrySof IQ, may prevent visual diseases like macular degeneration, but could also prevent life-threatening diseases like uveal melanoma High emission of blue-light in arc welding There is growing evidence implicating welding as a possible risk factor for uveal melanoma. The major culprit is high-energy blue light exposure (only UV-light is filtered by protective eyewear) Source: Miguel N. Burnier Jr., M.D. generates substances which are toxic to the RPE. As a result, RPE cells die and no longer nourish the retina, affecting vision.” Age-related macular degeneration clearly could result under such circumstances, he said. Putting excellent vision aside for the moment, consider life-threatening consequences of blue light toxicity, like uveal melanoma. “Laboratory rats exposed to long-term blue light develop intraocular masses, pathologically diagnosed as ocular melanoma,” Dr. Burnier said. Further, Dr. Burnier cited a study linking high energy light emitted from commercial welding to uveal melanoma. “There was evidence implicating welding as a risk factor for uveal melanoma,” Dr. Burnier said. But he added that there is a high emission of blue light in arc welding. In a letter to the journal Ophthalmology, Dr. Burnier wrote, “There is evidence suggesting that the major culprit is not ultraviolet light but blue light exposure. Okuno et al evaluated various light sources for blue light hazard. Among these sources, arc welding was found to have extremely high effective radiance, with corresponding permissible exposure times of only 0.6 to 40 seconds, suggesting that viewing this light source is very hazardous to the retina.” Dr. Burnier added that using UV and blue light filtering IOLs should be preferred for all adult patients undergoing cataract surgery, as it could be a preventative measure against possible blue light-induced malignant transformation. Critics of the AcrySof Natural IOLs have incorrectly suggested that the AcrySof Natural “blocks” blue light. They have suggested that blocking blue light could interfere with natural circadian rhythms regulated by melatonin and negatively impact sleep patterns and mood levels. The AcrySof Natural IOLs filter only a specific range of very highenergy blue light. A patient satisfaction questionnaire used at McGill, under the oversight of Dr. Burnier’s research team, found some enlightening results that all ophthalmologists need to know. Of 360 AcrySof Natural patients answering questions related to quality of vision after cataract surgery, none said they experienced insomnia or depression after cataract surgery. There is no definitive evidence to justify statements that the AcrySof Natural chromophore causes alleged problems with visual acuity, color perception, contrast sensitivity, circadian rhythms, or sleep pattern. These and other criticisms are shallow, Dr. Burnier said, such as those related to glistenings. The bottom line is that the AcrySof blue light filtering technology is not only beneficial to vision, but can prevent serious life-threatening conditions, Dr. Burnier said. There are strong indications that blue light filtering IOLs may play an important part in preserving vision for the long term. “For all these reasons, surgeons must use the gold standard in cataract surgery: Alcon blue light filtering IOLs,” Dr. Burnier said. Dr. Burnier has no financial interests related to this supplement. He can be contacted at 514-843-1544 or [email protected]. “Yellow is the gold standard. Yellow is the color that prevents blue light toxicity and concomitant problems.” Miguel N. Burnier Jr., M.D. 4 Achieving Success with Cataract and Refractive Technology A new tool to analyze how much the cataract incision influences the refractive outcome imbal relaxing incisions (LRIs) and other methods to address astigmatism have been around the ophthalmology block for a while, but as cataract surgery becomes more like refractive surgery, surgeons are looking for new ways to optimize outcomes. In this era of premium IOLs, surgeons have shifted their attention to surgically induced astigmatism (SIA), said Robert P. Lehmann, M.D., clinical associate professor of ophthalmology, Baylor College of Medicine, Houston, Texas. Surgeons now understand that whether they are implanting multifocal lenses, accommodating lenses or doing an LRI, to get more precise refractive results they must take SIA into account. Enter the Surgically Induced Astigmatism Calculator, designed by Warren E. Hill, M.D., available from his website, www.DoctorHill.com. “It’s an excellent fit with both the [AcrySof] Toric lens (Alcon, Fort Worth, Texas) and LRIs,” Dr. Lehmann said. “That’s the obvious place where you would first think of using it, as surgically induced astigmatism is a key element in the AcrySof Toric Calculator.” The AcrySof Toric Calculator (Alcon,www.AcrySofToricCalculator. com) takes into L “The Toric really allowed me to achieve a level of precision and success I never came close to with LRIs. It’s a precise and easy way for surgeons to transition into premium IOLs.” Robert Lehmann, M.D. account how much astigmatism you induce during surgery so that it can be compensated for in lens calculations. “It’s very applicable to toric lenses,” Dr. Lehmann said. “The calculator provides a default value but your results will be improved if your own SIA is used.” While there are a number of astigmatism calculators available, Dr. Lehmann said the SIA Calculator is the only one he would use because of Dr. Hill’s reputation and contributions to ophthalmology. “Warren Hill’s work has been second to none,” Dr. Lehmann said. Dr. Lehmann noted that smaller incisions cause less induced astigmatism. The range of possible induced astigmatism, for example, is greater with 3.0-mm incisions. “In that light, this [SIA Calculator] is going to be incredibly valuable, too,” he said, especially for surgeons who have had trouble optimizing results with some of the latest IOL technology. A tool like this [SIA Calculator] is going to enable a surgeon who has had an up and down love affair with premium implants to hone in and do a better job to get more precise refractive results, which is what it takes to make patients happy.” Dr. Lehmann added that surgeons cannot have more than half a diopter of uncorrected residual astigmatism in patients and expect to be successful with premium lenses. “These people want to function if at all possible with reduced dependence on glasses,” he said. Dr. Lehmann added that his surgically induced astigmatism with vector analysis is between 0.3 and 0.4 D, and he has excellent results with Toric IOLs. “The AcrySof Toric IOL really allowed me to achieve a level of precision and success I never came close to with LRIs. It’s a precise and easy way for all surgeons to transition into premium IOLs,” Dr. Lehmann said. “In my hands, I thought I was doing a good job [with LRIs]. With LRIs, patients might see really well on day one, but after the eye heals, residual astigmatism comes back. I don’t think I came close in 20 years to achieving the kind of results I have in two years with the Alcon Toric lens. On day one, 20/20 is not unusual now. LRIs now are a very poor second to Toric.” Dr. Lehmann is a consultant for Alcon, but states that he holds no financial interest in the products mentioned herein. He can be contacted at 936-569-8278 or [email protected]. A surgeon readies to implant an AcrySof Toric IOL Final alignment of the AcrySof Toric IOL Please visit www.Doctor-Hill.com and www.AcrySofToricCalculator.com for more information. Achieving Success with Cataract and Refractive Technology 5 Early experience with the AcrySof Toric IOL n ocular surgery, there are plenty of ways to manage astigmatism. One method is emerging as supremely advantageous: the AcrySof Toric IOL (Alcon, Fort Worth, Texas), according to Johnny Gayton, M.D., Eyesight Associates, Warner Robins, Ga. Incisions to correct astigmatism lack precision. They also lead to unpredictable outcomes and potential regression, not to mention their limited treatment range, I Dr. Gayton said. Lasers, meanwhile, can weaken the cornea. The ideal astigmatism treatment is precise and accurate with predictable outcomes; it is permanent, safe, and convenient. The AcrySof Toric IOL has proven to be an option that can meet these criteria. So who are the candidates for surgery? Patients who are “able to have lens surgery and also have significant regular corneal astigmatism, More than 60% of Toric patients achieved less than or equal to 0.5 D of absolute residual refractive cylinder at six months compared to about 20% of controls Of patients with bilateral implantation, 97% were spectacle-free Source: Johnny Gayton, M.D. whether or not it is asymmetric” are ideal, Dr. Gayton said. What’s more, he said, none of the multifocal contraindications apply, such as diabetic retinopathy, macular disease, or even “personality difficulties.” The Toric can also be combined with other more traditional astigmatism correcting procedures. A Toric and LRI at the time of surgery is one possible solution, as is a Toric and LRI post-op, and a Toric and laser vision correction. Conceivably, a surgeon could even employ all three methods. Dr. Gayton recommends that between 1.0 and 2.75 D of againstthe-rule astigmatism, a Toric IOL should be used. With 2.75 or greater against-the-rule astigmatism, a Toric and LRI could be used, correcting residual astigmatism with a laser. Between 0.5 and 2.25 D with-the-rule astigmatism is also suitable ground to employ the Toric only. For 2.25 or greater with-the-rule astigmatism, he suggested a Toric and LRI once again, correcting residual astigmatism with a laser. Don’t take Dr. Gayton’s word about the clinical benefits of Toric IOLs. The results speak for themselves in one multicenter clinical investigation in which 211 AcrySof Toric IOL eyes were compared to 210 control eyes. In the study, patients were three times more likely to achieve less than or equal to 0.5 D of residual refractive cylinder with the AcrySof Toric IOL than with the control group. More than 60% of Toric patients achieved less than or equal to 0.5 D of absolute residual refractive cylinder at six months compared to about 20% of controls. Further, the mean absolute residual refractive cylinder was 0.55 D for all AcrySof Toric IOL patients compared to 1.22 D for controls. Importantly, 97% of the 37 patients who were implanted bilaterally were spectacle-free for distance viewing. “The AcrySof Toric IOL demonstrates excellent rotational stability within the capsular bag,” Dr. Gayton said. The unique properties of the AcrySof material make it the optimal IOL to address astigmatism. Implantation of the Toric lens requires only minor variations from a standard cataract procedure. Surgeons determine the required spherical power using their preferred method. They then use the AcrySof Toric IOL Calculator (Alcon, www.acrysoftoriccalculator.com) to determine the correct IOL model and optimal axis location of the IOL in the capsular bag. The eye is marked on the limbus pre-op in three locations 90 degrees apart (3, 6, and 9 o’clock). Later, during the procedure, axis marks are placed on the eye using the pre-op reference marks. “Axis marks identify the optimal axis of IOL placement as determined by the AcrySof Toric IOL Calculator,” Dr. Gayton said. The lens is then rotated to its proper alignment. It’s that simple. This IOL technology has turned out to be a huge benefit for patients and surgeons. It’s an easy way for all surgeons to get involved in elective IOLs. Patients understand that they have astigmatism. They know they need it corrected in their glasses, in their contact lens, and now in their IOLs. Dr. Gayton has no financial interests related to this supplement. He can be contacted at 478-922-2994 or jlgayton@ aol.com. “The ideal astigmatism treatment is precise and accurate with predictable outcomes; it is permanent, safe, and convenient. The AcrySof Toric IOL has proven to be an option that can meet these criteria.” Johnny Gayton, M.D. 6 Achieving Success with Cataract and Refractive Technology Silo Scheduling: Proactive templates deliver the practice you desire magine a world in which more patients need to be cared for by your practice, but your practice nonetheless suffers more financial pressure as fees drop. Stop imagining because without making some changes, this will likely be the future. The baby boomer population is aging, bringing with it a tremendous amount of patients who need more “interactive, collaborative care from their medical provider,” said Kay Coulson, president, Elective Medical Marketing, Boulder, Colo. Specifically, in the next 20 years, the number of patients with cataracts are slated to increase 60%, and glaucoma patients will increase by 46%, Ms. Coulson said. Meanwhile, reimbursements have been and will continue to decline. “We’re at a critical threshold where efficiency alone cannot carve any additional time from a surgeon’s day,” Ms. Coulson said. Instead, ophthalmologists first need to revisit the services they provide. “We are rapidly moving into a period where further specialization of ophthalmologists will be required,” Ms. Coulson said. “The comprehensive practice that continues to schedule and treat patients simply as the phone rings will be overwhelmed within glaucoma and lens surgery requests.” Second, special scheduling help could ensure a practice’s I “Silo Scheduling allows a practice to create definition in its appointment calendar to deliver the right mix of patients.” Kay Coulson financial well-being. “Now is the time to revisit your appointment template and provide the visit type definition that reflects the type of practice and mix of patients you desire,” Ms. Coulson said. Silo Scheduling, a technique developed by Elective Medical Marketing, “allows a practice to create definition in its appointment calendar to deliver the right mix of patients, and more importantly, restrict visit types that threaten to overwhelm the practice,” Ms. Coulson said. See Figure A for an example of Silo Scheduling. So why can’t a practice simply analyze how to better optimize its own scheduling? “Adjusting the schedule template cannot be undertaken in isolation, as each practice must understand how visit types relate to diagnosis codes and revenue; there is not a one-to-one correlation,” Ms. Coulson said. Elective Medical Marketing has years of experience perfecting unique scheduling to find just the right financial solutions for practices. The way Ms. Coulson speaks about it, scheduling sounds like a science. “What Elective Medical Marketing has done for several of our clients is develop an appointment mix summary by silo and revenue realized per appointment type, correlating diagnosis codes to silos,” Ms. Coulson said. “This determines an event-to-appointment billing ratio.” Using the example worksheet shown in Figure B, a practice can perform a scenario analysis that indicates, for example, ‘If I reduce the glaucoma and pathology portions of my practice and concentrate on growing lens and LASIK surgery, how will my bottom line be affected?’” In that example, revenue was increased by 13% by revising the appointment mix. “These appointment mix percentages can then be built into the schedule template with reassurance that schedule changes will result in a positive bottom-line impact,” Ms. Coulson said. This way, ophthalmologists no longer have to feel overwhelmed caring for more patients as their practice suffers financially. By working smarter – with a little help from Silo Scheduling – they can put their worries behind them. Ms. Coulson is a consultant for Alcon. She can be contacted at 303-994-0014 or [email protected]. Figure A: An example of Silo Scheduling Figure B: Scenario analysis can be performed to determine how changing practice workloads will affect the bottom line This supplement was produced by EyeWorld under an educational grant from Alcon, Inc. Copyright 2008 ASCRS Ophthalmic Corporation. All rights reserved. The views expressed here do not necessarily reflect those of the editor, editorial board, or the publisher and in no way imply endorsement by EyeWorld or ASCRS. Achieving Success with Cataract and Refractive Technology 7 Are lifestyle IOLs worth it? Establishing realistic financial goals for upgraded lenses Before After Our hypothetical practice sees 40 cataract Exams per week evaluations per week, which include known cataracts, either from your diagnosis of patients presenting for a recheck, or referred in from ODs/non-surgical MDs. The number of evaluations is based on a weekly average over the prior 90 days. This practice performs 12 cataract surgeries Surgeries per week for a conversion rate of 15%. In our per week experience, we’ve found practices dramatically overestimate their surgical conversion, with 15 to 20% being the industry average. This practice implemented Silo Scheduling, blocking the same 40 weekly consultations into two mornings per week, separate from all other appointment types, rather than dispersing them throughout the schedule. Blocking all cataract evaluations into two days and ensuring all staff are geared on those mornings toward evaluating and educating patients about lens surgery options increased surgical conversions to 25%, resulting in 20 surgical eyes per week versus 12 from the same 40 exams. Lens mix This practice was dabbling in presbyopic IOLs and had not begun implanting toric IOLs. They perform LRIs, but did not charge for them as they considered results too unpredictable. All cataract evaluation patients were mailed educational materials one week ahead of their visit. These materials covered all lens options, procedure costs, and patient testimonials. In addition, each patient filled out the Vision Preferences Checklist, and all were shown a multifocal testimonial DVD while dilating. Conversion to lifestyle IOLs increased from 5% to 35%. Fees This practice charged $3,000 per eye for a presbyopic IOL, and as part-owner of its ASC, paid $745 incrementally for multifocal lenses (above the $150 ASC reimbursement). Realizing the $3,000 fee was preventing adoption by many interested patients, this practice lowered its presbyopic IOL fee to $1,975 per eye, and added an astigmatism management service at $975 per eye. o-called “lifestyle IOLs” – that is, multifocal or pseudoaccommodative ones – clearly have more potential for profit as associated fees are higher than with standard IOLs. But before offering them in your practice, wouldn’t it be good to know the likely financial outcome of doing so? Other businesses carefully study the advantages of new product lines before they offer them. Why shouldn’t you? The Lifestyle IOL Financial Calculator, a method developed by Elective Medical Marketing (Boulder, Colo.), allows ophthalmologists to “evaluate current practice performance and set targets for specific areas of improvement that can be continually monitored as your practice expands,” said Kay Coulson, the company’s president. S The chart above shows beforeand-after scenarios of one hypothetical practice, which with the help of some of the method’s implementation steps, dramatically increased revenue by more than 75%. The chart was provided by Elective Medical Marketing. As a result of the practice changes made, revenue increased from $476,000 to $835,000 annually without having to do any more cataract evaluations. “This revenue increase of more than $350,000 is the result of increased practice focus on the patient experience through Silo Scheduling and pre-exam education,” Ms. Coulson said. Ms. Coulson is a consultant for Alcon. She can be contacted at 303-994-0014 or [email protected] Schwiegerling from page 1 Overall, it is wise for all IOLs to move to the aspheric platform, Dr. Schwiegerling said. While today’s IOL technology is excellent, any small improvement will still make a difference, he said. Dr. Schwiegerling did note that the aspheric design had no impact on near vision in ReSTOR patients. “I think that’s fairly predictable,” Dr. Schwiegerling said. “Most aspheric effects only account for large pupil conditions.” In the ReSTOR lens, the peripheral part of the IOL – through which light would pass in large pupil conditions – is strictly for distance vision. So the fact that Dr. Schwiegerling said most aspheric effects are noted in large pupil conditions means they are notable for distance vision, and not particularly for near vision. Near vision in the ReSTOR, Dr. Schwiegerling said, is achieved with the central 3.6 mm of the lens. Meanwhile, Dr. Schwiegerling said, intermediate vision is probably the same in both the aspheric and standard ReSTOR IOLs. “It was difficult from our findings to see any differences one way or another,” Dr. Schwiegerling said. Of course, modulation transfer function testing does not gauge any neuroadaptivity that occurs related to quality of vision. After some time, symptomatic patients may not notice halos and glare even with the standard ReSTOR IOL in larger pupil conditions because their brains have adapted to screen them out. Nonetheless, a better optical system, like the aspheric design, can only help to lessen these effects further. Dr. Schwiegerling receives travel, honoraria, and research grants from Alcon. He can be contacted at 520-3223800 x210 or [email protected]. Unlike IOLs that do not closely match the light-transmission spectrum of the human crystalline lens*, the patented chromophore in the AcrySof® Natural IOL is designed to filter UV wavelength and blue light in the 400 –475nm range. “Objective, peer-reviewed studies have shown that “Having participated in the clinical investigation of the blue-light filtering IOLs have no significant effect on color Natural chromophore and seeing for myself real-life patient perception. There are strong indications that blue-light benefits, I am gratified by the increasing worldwide acceptance of the AcrySof® Natural platform. This lens is filtering IOLs may play an important role for patients quickly becoming the standard of care as more companies in the long-term. In my experience, the potential benefits are attempting to copy this technology and following suit. outweigh unsubstantiated claims of altered circadian ” rhythms and other marketing hype. James McCulley, MD Founder and Director of Lehmann Eye Center Professor and Chairman, Department of Ophthalmology UT Southwestern Medical Center at Dallas (USA) “I have implanted the AcrySof ® ” Robert Lehmann, MD Clinical Associate Professor, Baylor College of Medicine (USA) “Over the last five years I have implanted more than Natural IOL for ten years, and it possesses a long-term track record of excellent 10,000 blue-light filtering lenses, I also implanted this lens in clinical performance. The AcrySof® design, material and my wife and both my parents. There is no definitive evidence Natural chromophore combine to provide great benefits to to justify statements that the AcrySof® Natural chromophore causes alleged problems with visual acuity, color perception, my patients. This is the IOL I would want if I were a patient. As a surgeon concerned with my patient’s best interests, using it allows me to sleep soundly each night. Stephen Lane, MD ” Adjunct Clinical Professor, ” contrast sensitivity, circadian rhythms or sleep pattern. Richard Mackool, MD Founder and Director of The Mackool Eye Institute Assistant Clinical Professor, University of Minnesota, St. Paul (USA) “Although it may take years to determine every benefit associated with the Natural lens, there have certainly been many clinical studies done that strongly support its safe use. Excellent clinical performance provided me the confidence to implant AcrySof Natural IOLs in my wife ® ” and my sister. Samuel Masket, MD Clinical Professor, UCLA, Jules Stein Eye Institute, Los Angeles (USA) New York Medical College, New York (USA) “I believe very strongly that the AcrySof ® blue-light filtering IOLs should be the standard of care for all patients. In my peer-reviewed studies, we have presented laboratory evidence that clear and/or violet IOLs do not have the ” qualities of the Natural chromophore. Miguel Burnier, Jr., MD Thomas Hecht Family Chair of Ophthalmology and Director of the Henry C. Witelson Eye Pathology Laboratory, McGill University, Montreal (Canada) References; (*) Alcon, Inc. Data on File and Human lens data from Boettner and Wolter, 1962 © 2008, Alcon, Inc. ACR586
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