onsite programme
Transcription
onsite programme
ONSITE PROGRAMME 13TH INTERNATIONAL CONFERENCE OF THE INTERNATIONAL MESOTHELIOMA INTEREST GROUP Follow us on Twitter @iMig_meso for updates during the Conference! iMig 2016 wishes to warmly thank the following organizations for their generous support of the Conference: GOLD SPONSORS SILVER SPONSORS BRONZE SPONSORS SUPPORTERS EDUCATIONAL GRANT PROVIDER This meeting is supported by an unrestricted educational grant from Roche Products Ltd. who have had no input into the meeting agenda or content. This meeting is supported by an unrestricted educational grant from Concordia Laboratories Inc. who have had no input into the meeting agenda or content. GENERAL SUPPORT iMig 2016 would like to thank the following organizations for their support of the Conference: Cancer Research UK Leicester Centre MRC Toxicology Unit TABLE OF CONTENTS SCIENTIFIC INFORMATION CONFERENCE INFORMATION Welcome Message 2 International Mesothelioma Interest Group 3 Committees 3 Scientific Programme Programme at a Glance 4 Monday, May 2, 2016 6 Tuesday, May 3, 2016 18 Wednesday, May 4, 2016 30 Information for Invited Speakers and Abstract Presenters 32 Conference Information 37 37 Floor Plans General Information from A to Z 38 Awards 44 iMig Wagner Medal 44 iMig Medal 44 iMig Award 44 Best Investigator Award 45 Young Investigator Awards 45 Developing Nations Travel Grants 45 Special Workshop: Mesothelioma Nurse Meeting 46 Industry-Supported Symposia 49 Exhibition Information Location, Hours and Highlights 50 Exhibitor Listing 54 Exhibition Floor Plan 55 Exhibitor Biographies 56 GENERAL SUPPORT iMig 2016 is organized under the auspices of the iMig2016.ORG iMig 2016 is endorsed by the 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 1 WELCOME MESSAGE It is a great pleasure and an honour to extend you a warm invitation to attend the 13th International Conference of the International Mesothelioma Interest Group (iMig 2016), to be held May 1–4, 2016 at the International Conference Centre in Birmingham, UK. Building on the success of preceding meetings in Boston in 2012 and Cape Town in 2014, the Conference will feature a highly interactive, stimulating and multidisciplinary Programme including workshops, plenary sessions as well as oral abstract and poster sessions. Under the theme of ‘Towards Personalized Care’ the meeting will address the entire patient pathway and look beyond the scientific topics alone. The Conference will provide the ideal forum to stimulate ideas and establish collaborations as well as to initiate intense discussions. Extended networking opportunities will foster communications between delegates. It is an exciting time for mesothelioma research and we hope to see you in Birmingham in 2016 for the iMig 2016 Conference. With best wishes,   David Waller Glenfield Hospital 2 Dean A. Fennell University of Leicester 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG INTERNATIONAL MESOTHELIOMA INTEREST GROUP WWW.IMIG.ORG The International Mesothelioma Interest Group (iMig) is an independent international group of scientists and clinicians working to understand, cure and prevent Mesothelioma. We invite you to become a member of iMig to strengthen our international voice and to improve the scientific exchange and knowledge about this malignancy. WHY JOIN IMIG? Membership is about communication and participation. Members will have access to all features of the iMig website (iMig.org) and opportunities to contribute content there. Via email, members will receive notices of updates to the website such as those involving upcoming meetings, funding or career opportunities, new presentations and research breakthroughs. Although no membership dues are requested at this time, members are asked to participate in iMig by contributing to the website and/or participating in the biannual international meetings. Finally, members help iMig by being part of our international community and showing their interest in understanding and ultimately preventing and defeating Mesothelioma. iMig2016.ORG iMig OFFICERS 2014 – 2016 President: Dean Fennell, PhD, MRCP, Leicester, United Kingdom Secretary: Jeremy Steele, MD, MRCP, London, United Kingdom Treasurer: Paul Baas, MD, PhD, Amsterdam, The Netherlands iMig BOARD MEMBERS 2014 – 2016 Steve Albelda, MD, Philadelphia, USA Samuel Armato, PhD, Chicago, USA Paul Baas, MD, PhD, Amsterdam, The Netherlands Courtney Broaddus, MD, San Francisco, USA Dean Fennell, MD, PhD, Leicester, United Kingdom Rabab Gaafar, MD, Cairo, Egypt Marie-Claude Jaurand, PhD, Paris, France Hedy Lee Kindler, MD, Chicago, USA Steven Mutsaers, MD, PhD, Perth, Australia Luciano Mutti, MD, PhD, Vercelli, Italy Takashi Nakano, MD, PhD, Hyogo, Japan Bruce Robinson, MD, Perth, Australia Arnaud Scherpereel, MD, PhD, Lille, France Jeremy Steele, MD, London, United Kingdom Daniel Sterman, MD, Philadelphia, USA Jim teWaterNaude, MBChb, Cape Town, South Africa Walter Weder, MD, Zurich, Switzerland LOCAL ORGANIZING COMMITTEE Co-Chairs: David Waller, MD, Leicester, United Kingdom Dean Fennell, PhD, MRCP, Leicester, United Kingdom Samuel Armato, PhD, Chicago, USA Sara Busacca, Leicester, United Kingdom Liz Darlison, Leicester, United Kingdom Laurie Kazan-Allen, London, United Kingdom Marion MacFarlane, PhD, Leicester, United Kingdom Luciano Mutti, MD, PhD, Vercelli, Italy Mick Peake, MD, Leicester, United Kingdom Sanjay Popat, BSc, PhD, FRCP, London, United Kingdom Annabel Sharkey, Leicester, United Kingdom Jeremy Steele, MD, London, United Kingdom Lynne Squibb, Southampton, United Kingdom Ian Woolhouse, Birmingham, United Kingdom 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 3 PROGRAMME AT A GLANCE MONDAY | MAY 2 08:00 08:30 09:00 09:30 Plenary Session I: Origins of Mesothelioma [08:25 – 10:25] 10:00 10:30 11:00 11:30 12:00 12:30 13:00 13:30 14:00 14:30 15:00 15:30 16:00 16:30 Networking Break and Poster Viewing Plenary Session II: Predicting the Outcome [11:15 – 12: 45] Networking Break and Poster Viewing [12: 45 – 14:15] Lunchtime Session [13:15 – 14:15] Parallel Mini Symposia 1–4 [14:15 – 15: 45] Networking Break and Poster Viewing 17:00 Parallel Mini Symposia 5–8 17:30 [16: 30 – 18: 00] 18:00 18:30 19:00 Poster Mixer with Poster Discussions [18: 00 – 19: 30] 19:30 20:00 20:30 21:00 4 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG TUESDAY | MAY 3 WEDNESDAY | MAY 4 Industry-Supported Symposium Industry-Supported Symposium 08:00 [08: 00 – 08: 45] [08: 00 – 08: 45] 08:30 Plenary Session III: The Knife or the Needle? Plenary Session V: What is in the Locker Now? [09: 00 – 10: 30] [09: 00 – 10: 30] Networking Break and Poster Viewing Networking Break and Poster Viewing Plenary Session IV: From Genetics to Therapy Plenary Session VI: The “Immune War” on Mesothelioma [11:15 – 12: 45] [11:15 – 12: 45] 09:00 09:30 10:00 10:30 Networking Break and Poster Viewing [12: 45 – 14:15] Parallel Mini Symposia 9–12 11:30 12:00 12:30 Presidential Closing and Invitation to iMig 2018 Industry-Supported Symposium [13:15 – 14:15] 11:00 13:00 13:30 Young Investigator’s Session [13: 30 – 15: 30] 14:00 14:30 15:00 [14:15 – 15: 45] 15:30 16:00 Networking Break and Poster Viewing 16:30 Parallel Mini Symposia 13–16 17:00 [16: 30 – 18: 00] 17:30 18:00 18:30 Poster Mixer with Poster Discussions [18: 00 – 19: 30] 19:00 19:30 20:00 20:30 21:00 *subject to change iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 5 MONDAY, MAY 2, 2016 INITIATION AND DETECTION OF MESOTHELIOMA 08:25 – 10:25 PL01: Plenary Session I: Origins of Mesothelioma Chairs: Jim teWaterNaude, South Africa & Dean Fennell, United Kingdom & Daniel Sterman, USA Hall 1 08:25 PL01.01: Welcome Address Dean Fennell, University of Leicester, United Kingdom 08:30 PL01.02: The Global Meso Epidemic Julian Peto, London School of Hygiene and Tropical Medicine, United Kingdom 08:50 PL01.03: Chrysotile and Cancer Julian Peto, London School of Hygiene and Tropical Medicine, United Kingdom & David Egilman, Brown University, USA 09:10 PL01.07: The Genomic Landscape of Mesothelioma Patrick Tarpey, Wellcome Trust Sanger Institute, United Kingdom 10:00 PL01.08: How the Genome Affects Outcome Raphael Bueno, Brigham and Women’s Hospital and Harvard Medical School, USA 10:15 PL01.09: Constitutive YAP Activation Induces Malignant Phenotypes of Immortalized Mesothelial Cells Yoshitaka Sekido, Aichi Cancer Center Research Institute, Japan 10:30 – 11:15 Networking Break and Poster Viewing Hall 3 PL01.04: Pleural Mesothelioma and Asbestos Exposure: A CaseControl Study with Quantitative Risk Assessment 11:15 – 12:45 Daniela Ferrante, University of Eastern Piedmont, Italy PL02: Plenary Session II: Predicting the Outcome 09:20 PL01.05: Mechanisms of Asbestos Carcinogenesis and HMGB1 Haining Yang, University of Hawaii Cancer Center, USA Chairs: Steve Mutsaers, Australia & John Edwards, United Kingdom & Sam Armato, USA 09:35 PL01.06: Long-Fibre Carbon Nanotubes Induce Pleural Mesothelioma via Silencing and/ or Loss of Key Tumour Suppressor Genes 6 09:45 Hall 1 11:15 PL02.01: “The Bad Macrophage Story” Lisa Coussens, Oregon Health & Science University, USA Tatyana Chernova, MRC Toxicology Unit, United Kingdom 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 PL02.02: Clinico-Pathological Staging - the New IASLC System Valerie Rusch, Memorial Sloan Kettering Cancer Center, USA 11:55 PL02.03: Impact of Tumor Thickness on Survival after Accelerated Hemithoracic Radiation Followed by Extrapleural Pneumonectomy Marc De Perrot, Toronto General Hospital and Princess Margaret Cancer Center, Canada 12:05 PL02.04: “Bio Staging” - the Future Kenneth O’Byrne, Queensland University of Technology, Australia 12:25 PL02.05: Mutation Profiles of Malignant Pleural Mesotheliomas According to Molecular Classification Lisa Quetel, INSERM U.1162, France 12:35 PL02.06: Final Q & A 14:15 – 15:45 PARALLEL MINI SYMPOSIA 1 - 4 MS01: Mini Symposium 1: MARF International Meso UK Mini Symposium Chairs: Mary Hesdorffer, USA & Liz Darlison, United Kingdom & Judy Rafferty, Australia Hall 10a 14:15 MS01.01: Welcome Liz Darlison, Mesothelioma UK, United Kingdom 14:20 MS01.02: Managing Toxicities & Supporting Patients through Radical Radiotherapy Anastasia Bykova, University Health Network, Canada 14:40 MS01.03: Surgical Panel Joseph Friedberg, University of Maryland School of Medicine, USA & Walter Weder, University Hospital Zurich, Switzerland & John Edwards, Northern General Hospital, United Kingdom & Melissa Culligan, University of Maryland, USA 15:10 MS01.04: Programme for Nurses to Improve Communication Skills in the Care of People With Mesothelioma in Japan Yasuko Nagamatsu, St. Luke’s International University, Japan 15:20 MS01.05: Mesothelioma Patients’ and Carers’ Concerns about Their Diagnosis, Treatment, and Care Kate Hill, Leeds Institute of Health Sciences, United Kingdom 12:45 – 14:15 Networking Break and Poster Viewing Hall 3 13:00 – 14:00 SS02: Lunchtime Session: How Much Cancer Does Chrysotile Cause? Chairs: Jim teWaterNaude, South Africa & Laurie Kazan-Allen, United Kingdom Hall 1 13:15 SS02.01: How Much Cancer Does Chrysotile Cause? Julian Peto, London School of Hygiene and Tropical Medicine, United Kingdom, David Egilman, Brown University, USA iMig2016.ORG MONDAY, MAY 2 11:35 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 7 MONDAY, MAY 2 MS01.06: Asbestos-Related Disease Support Groups: A Survey of Their Organisational Structures and Activities 15:00 MS02.05: Tissue Transglutaminase (TG2): A Potential Novel Target for Human Malignant Pleural Mesothelioma Treatment Helen Clayson, Glasgow Caledonian University, United Kingdom Giulia Pinton, University of Piemonte Orientale, Italy 15:40 MS01.07: Close 15:10 Liz Darlison, Mesothelioma UK, United Kingdom MS02.06: Autophagy Inhibition Sensitizes Primary Malignant Mesothelioma to a Dual PI3K/mTOR Inhibitor Sara Galavotti, MRC Toxicology Unit, United Kingdom MS02: Mini Symposium 2: Cell Death Mechanisms 15:20 MS02.07: Autophagy Correlates with Patient Outcome in Mesothelioma Chairs: Courtney Broaddus, USA & Marion MacFarlane, United Kingdom Carlo Follo, University of California San Francisco, USA 15:30 MS02.08: What Have We Learned? Marion Macfarlane, MRC Toxicology Unit / Cancer Research UK Centre, United Kingdom MONDAY, MAY 2 15:30 8 14:15 – 15:45 Hall 10b 14:15 MS02.01: Setting the Stage for Cell Death Courtney Broaddus, University of California San Francisco, USA 14:30 MS02.02: Signalling Pathways Involved in Upregulation of MCL1 in MM; Metabolic Reprogramming Provides a Novel Approach to Sensitise MM Xiao-Ming Sun, MRC Toxicology Unit, United Kingdom 14:40 MS02.03: Monoamine Oxydase A as a Potential New Target to Treat Malignant Pleural Mesothelioma Christophe Blanquart, University of Nantes, France 14:50 MS02.04: EGFR Tyrosine Kinase Inhibitors Overcome Resistance to Chemotherapy in Malignant Pleural Mesothelioma Ludovic Dhont, Interdisciplinary Cluster for Applied Genoproteomics (GIGA) of University of Liège, Belgium 14:15 – 15:45 MS03: Mini Symposium 3: Imaging and Endpoint Evaluation Chairs: Samuel Armato, USA & Anna Nowak, Australia Hall 6 14:15 MS03.01: Indocyanine Green and Intraoperative Imaging Detects Residual Disease Following Resection of Malignant Pleural Mesothelioma Jane Keating, University of Pennsylvania, USA 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 MS03.02: The Value of Delayed Phase Enhancement for Magnetic Resonance Imaging of Malignant Pleural Mesothelioma Sharyn Katz, University of Pennsylvania Perelman School of Medicine, USA 14:35 MS03.03: Optimisation of the Methods for Early Contrast Enhancement (ECE)-Magnetic Resonance Imaging in Patients with Mesothelioma Selina Tsim, Queen Elizabeth University Hospital, United Kingdom 14:45 MS03.04: Histogram Analysis of DWMRI Data during Early Chemotherapy Response Predicts Outcome of Inoperable MPM Patients Johan Coolen, University Hospitals of Leuven, Belgium 14:55 MS03.05: Correlation of CT Scan Based Tumor Volume Measurement to Actual Resected Tumor Weight: A New T-Factor? Isabelle Opitz, University Hospital Zürich, Switzerland 15:05 MS03.06: Dynamic ContrastEnhanced CT for the Assessment of Tumor Response in Malignant Pleural Mesothelioma: A Pilot Study Eyjolfur Gudmundsson, University of Chicago, USA 15:15 MS03.07: Modified RECIST for Mesothelioma: Lessons Learned and Gaps in Application Anna Nowak, University of Western Australia, Australia 15:25 MS03.08: Toward Modified RECIST 1.1 for Mesothelioma: Closing the Gaps and Meeting Present-Day Needs Sam Armato, University of Chicago, USA iMig2016.ORG 15:35 MS03.09: Final Q & A 14:15 – 15:45 MS 04: Mini Symposium 4: Cell and Vaccine Based Therapy Chairs: Bruce Robinson, Australia & Steve Albelda, USA Hall 9 14:15 MS04.01: Introduction MONDAY, MAY 2 14:25 14:25 MS04.02: Experimental Models of Human Malignant Mesothelioma in NOD SCID Mice and Nude Rats for Evaluation of in Vivo Virotherapy Joëlle Nader, UMR 892 INSERM / 6299 CNRS, France 14:35 MS04.03: Tumour Suppressor microRNAs Regulate PD-L1 Expression in Malignant Pleural Mesothelioma Marissa Williams, Asbestos Diseases Research Institute, Australia 14:45 MS04.04: PD-1+ T Cells in Mesothelioma Effusions Induce Tumor PD-L1 Expression Making Them Susceptible to Avelumab Mediated ADCC Raffit Hassan, National Cancer Institute, USA 14:55 MS04.05: Harnessing the Immune System-Adjuvant Immunotherapy for Mesothelioma Jarrod Predina, University of Pennsylvania School of Medicine, USA 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 9 MONDAY, MAY 2 MS04.06: Intrapleural Modified Vaccine Strain Measles Virus Therapy for Patients with Malignant Pleural Mesothelioma - A Phase I Trial Tobias Peikert, Mayo Clinic, USA 15:15 MS04.07: Nivolumab in Malignant Pleural Mesothelioma (NivoMes): An Interim Analysis Josine Quispel-Janssen, Netherlands Cancer Institute, Netherlands MONDAY, MAY 2 15:05 16:40 MS05.02: Haptoglobin Phenotype Is a Risk Factor for Malignant Pleural Mesothelioma Kevin Lamote, Ghent University Hospital, Belgium 16:50 MS05.03: HMGB1 and Its Isoform Are Sensitive and Specific Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients Haining Yang, University of Hawaii Cancer Center, USA 17:00 MS05.04: Expression of microRNAs in MPM as Tool to Identify Novel Therapeutic Targets and Diagnostic/ Prognostic Biomarkers 15:25 MS04.08: Immune Responses following Intrapleural Administration of Oncolytic HSV1716 in Patients with Malignant Pleural Mesothelioma Kevin Blyth, Queen Elizabeth University Hospital, United Kingdom Chiara De Santi, University of Pisa, Italy MS04.09: Final Q & A 17:10 MS05.05: The Role of Multidisciplinary Diagnostic/ Therapeutic Pathway in the CaseManagement of Suspected Pleural Mesothelioma Cristian Rapicetta, Arcispedale Santa Maria Nuova-IRCCS, Italy 17:20 MS05.06: Launching the North West Regional Mesothelioma MDT; Defining the Patient Pathway Lorraine Creech, University Hospital of South Manchester, United Kingdom 17:30 MS05.07: Final Q & A 15:35 15:45 – 16:30 Networking Break and Poster Viewing Hall 3 16:30 – 18:00 PARALLEL MINI SYMPOSIA 5 - 8 MS05: Mini Symposium 5: Optimum Diagnostic Pathway for Suspected Mesothelioma Chairs: Takashi Nakano, Japan & Robert Rintoul, United Kingdom Hall 6 10 16:30 MS05.01: MesobanK - Today’s Biospecimens for Tomorrow’s Medicine Robert Rintoul, Papworth Hospital NHS Foundation Trust, United Kingdom 16:30 – 18:00 MS06: Mini Symposium 6: Asbestos Control Chairs: Jim teWaterNaude, South Africa & Laurie Kazan-Allen, United Kingdom Hall 9 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 MS06.01: Turkey National Mesothelioma Surveillance Program and Asbestos Control Muzaffer Metintas, Eskisehir Osmangazi University, Turkey 16:40 MS06.02: Mesothelioma Mortality At 10-year Follow-up In The Atom 002 Screening Study Ornella Belvedere, York Hospital, United Kingdom 16:50 MS06.03: Factors Influencing the Asbestos Bodies among Pleural Mesotheliomas and Lung Cancers Examined for Retained Asbestos Fibres Enzo Merler, Venetian Mesothelioma Registry, Italy 17:00 MS06.04: An Ecological Analysis of Cohorts with Environmental and Occupational Mineral Fiber Exposure Selma Metintas, Eskisehir Osmangazi University, Turkey 17:10 MS06.05: The Impact of Geographic and Socioeconomic Factors on Prognosis and Treatment Provision in Malignant Pleural Mesothelioma 16:30 – 18:00 MS07: Mini Symposium 7: BAP1 and Genetics Chairs: Michele Carbone, USA & Marc Ladanyi, USA Hall 10a 16:30 MS07.01: Association of BAP1 Gene Expression with Protein Localization and Survival in Epithelioid MPM Assunta De Rienzo, Brigham and Women’s Hospital and Harvard Medical School, USA 16:40 MS07.02: Somatic BAP1 and NF2 Mutations in Pleural Malignant Mesothelioma and Their Correlation with Clinical Phenotypes Spyridon Gennatas, Imperial College London, United Kingdom 16:50 MS07.03: Families with Multiple Cases of Pleural Malignant Mesothelioma without Inheritance of a BAP1 Predisposing Mutation Valeria Ascoli, Sapienza University, Italy 17:00 MS07.04: BAP1 and Mesothelioma Michele Carbone, University of Hawaii Cancer Center, USA 17:10 MS07.05: BAP-1 Cancer Syndrome Associated Malignancies Were Not Detected among 558 Danish Patients with Malignant Mesothelioma Anthony Linton, Asbestos Diseases Research Institute, Australia 17:20 MS06.06: Risk of Second Primary Cancers after Malignant Mesothelioma and Vice Versa Tianhui Chen, Zhejiang Academy of Medical Sciences, China Vasiliki Panou, Aalborg University Hospital & Aalborg University, Denmark 17:30 MS06.07: Mesothelioma Incidence in Sweden - Why Does It Not Go Down? 17:20 MS07.06: Final Q & A Gunnar Hillerdal, Gävle Hospital, Sweden 17:40 MS06.08: Final Q & A iMig2016.ORG MONDAY, MAY 2 16:30 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 11 MONDAY, MAY 2 16:30 – 18:00 17:30 MS08.07: The Crucial Clinicopathological Approach in Superficial Mesothelial Proliferations; MESOPATH Experience Francoise Galateau Salle, Cancer Center Leon Berard, France 17:40 MS08.08: Multi-Omics Integration for Malignant Pleural Mesothelioma Subtypes Characterization Yuna Blum, Ligue Nationale Contre Le Cancer, France 17:50 MS08.09: Final Q & A MS08: Mini Symposium 8: Pathology MONDAY, MAY 2 Chairs: Marie-Claude Jaurand, France & Doris Rassl, United Kingdom 12 Hall 10b 16:30 MS08.01: Immunohistochemical Detection of MTAP or BAP1 Protein Loss for Mesothelioma Diagnosis: Comparison with p16 FISH Kazuki Nabeshima, Fukuoka University School of Medicine, Japan 16:40 MS08.02: Utility of BAP1 Immunohistochemistry and FISH in the Differential Diagnosis of Malignant Mesothelioma Kenzo Hiroshima, Tokyo Women’s Medical University, Japan 16:50 MS08.03: Histological Evaluation of Mesotheliomas Gregor Vlacic, University Clinic Golnik, Slovenia 17:00 MS08.04: A Gene Panel to Differentiate Malignant Pleural Mesotheliomas from Benign Pleural Lesions Rossella Bruno, University of Pisa, Italy 17:10 MS08.05: Necrosis and Solid Growth Pattern Augment Nuclear Grading in Predicting Survival in Epithelioid Malignant Mesothelioma Aliya Husain, University of Chicago, USA 17:20 MS08.06: Peritoneal Mesothelioma: Evaluation on Pathology Reporting Valeria Ascoli, Sapienza University, Italy 18:00 – 19:30 PP01 Poster Mixer and Poster Discussion Session 1 Moderators: Michael Peake, United Kingdom & Sam Armato, USA & Kevin Blyth, United Kingdom & Marie Claude Jaurand, France & Faheez Mohamed, United Kingdom & Courtney Broaddus, USA & Marion MacFarlane, United Kingdom Hall 3 PP01.01: Systemic Inflammation Consistently Predicts Adverse Outcome Based on Multiple Biomarkers in Patients with Mesothelioma Michael McGettrick, Queen Elizabeth University Hospital, United Kingdom PP01.02: An Update on DIAPHRAGM: A Prospective, Multi-Centre Study of Fibulin-3 and SOMAscan as Biomarkers in Mesothelioma Selina Tsim, Queen Elizabeth University Hospital, United Kingdom 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 Taiichiro Otsuki, Hyogo College of Medicine, Japan PP01.04: PI3-Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma PP01.10: Prognostic Significance of Mitotic Arrest Deficient 2-Like Protein 1 in Malignant Mesothelioma Aaron Mansfield, Mayo Clinic, USA PP01.11: Brain-Derived Neurotrophic Factor (BDNF) and Fibulin-3 as Biomarkers for Diagnosis of Malignant Pleural Mesothelioma (MPM) Rajani Kanteti, University of Chicago, USA Sarah Benziane, Hospital of the University (CHU) of Lille, France PP01.12: Target Trial PP01.05: Early Diagnosis by Cytology Improves Survival Anders Hjerpe, Karolinska University Hospital, Sweden PP01.06: Low Merlin Expression and High Survivin Staining Index are Indicators for Poor Prognosis of Malignant Mesothelioma Patients Mayura Meerang, University Hospital Zürich, Switzerland PP01.07: MicroRNAs in Blood as Biomarker of Pleural Malignant Mesothelioma Dario Consonni, Fondazione IRCCS Ca’ Granda - Ospedale Maggiore Policlinico, Italy Duneesha De Fonseka, North Bristol NHS Trust, United Kingdom PP01.13: Ex Vivo Effects of Pemetrexed and Carboplatin on Malignant Mesothelioma Cells Carl-Olof Hillerdal, Karolinska Institutet, Sweden PP01.14: Diagnosing Mesothelioma via Chest Wall Motion Analysis Technology Ghazi Elshafie, Heartlands Hospital, United Kingdom PP01.15: Circulating Level of the Complement Component 4d (C4d) Correlates with Chemotherapeutic Response and Survival in MPM Patients PP01.08: Septin-7, Lipoma Preferred Partner and Transaldolase Discriminate Neoplastic From Preneoplastic Mesothelial Cells PP01.16: VOC Analysis in Headspace Air of Mesothelioma and Lung Cancer Cell Lines: A Comparative Literature Study Daniel Pouliquen, UMR 892 INSERM / 6299 CNRS, France PP01.09: Col3A1, a New Potential Immunohistological Marker for the Diagnosis of Malignant Pleural Mesothelioma Christophe Blanquart, INSERM UMR 892 / CNRS 6299, France Thomas Klikovits, Medical University of Vienna, Austria Sabrina Lagniau, Ghent University, Belgium PP01.17: Prognostic Biomarkers in a Large Cohort of Patients with Malignant Pleural Mesothelioma - a Retrospective TwoCenter Study iMig2016.ORG MONDAY, MAY 2 PP01.03: Examination of the Serum Soluble Mesothelin-Related Peptide (SMRP) Level in Patients with Malignant Pleural Mesothelioma Thomas Klikovits, Medical University of Vienna, Austria 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 13 MONDAY, MAY 2 PP01.18: Changes in Monocyte Count and Lymphocyte-To-Monocyte Ratio during Induction Chemotherapy Correlate with Clinical Outcome MONDAY, MAY 2 Jens Sørensen, Finsen Centre/National University Hospital, Denmark PP01.28: Phase I Trial of Lentiviral CART-Meso Cells in Progressive Malignant Pleural Mesothelioma (MPM) Luca Ampollini, University Hospital of Parma, Italy Steven Albelda, University of Pennsylvania, USA PP01.21: Serum Biomarkers in Mesothelioma 1-3 Years before Diagnosis: A Pilot Study PP01.29: Does Malignant Pleural Mesothelioma with Metastases at First Presentation Really Benefit from Chemotherapy? Oluf Røe, Norwegian University of Science and Technology, Norway PP01.22: Role of EPHA2 in Malignant Mesothelioma Yi-Hung Carol Tan, University of Chicago, USA Bruce Robinson, University of Western Australia, Australia PP01.24: Prognostic microRNAs in Tissues from Malignant Pleural Mesothelioma Patients Receiving Multimodality Therapy Michaela Kirschner, University Hospital Zurich, Switzerland Guntulu Ak, Eskisehir Osmangazi University, Turkey Nicholas De Klerk, University of Western Australia, Australia PP01.31: Preliminary Report of an Observational Clinical Registry on Malignant Pleural Mesothelioma (MPM) in Italy (REGCLIN) Federica Grosso, SS. Antonio e Biagio e C. Arrigo, Hospital, Italy PP01.32: Slowly Progressive Malignant Pleural Mesothelioma in Aged Patients PP01.25: Chemotherapy and Chemotherapy Plus Talc Pleurodesis In Treatment of Malignant Pleural Mesothelioma: A Retrospective Analysis Hala Aziz Shokralla, National Cancer Institute, Egypt PP01.30: Mesothelioma Mortality in Australian and Italian-Born Workers Exposed to Blue Asbestos at Wittenoom, Western Australia PP01.23: ENOX2-Based Early Detection of Malignant Mesothelioma Mizue Hasegawa, Tokyo Women’s Medical University, Japan PP01.33: A Cohort of Malignant Pleural Mesothelioma Treated and Followed in the Last Ten Years at Instituto OncolóGico Henry Moore 14 Hasan Batirel, Marmara University, Turkey PP01.27: Fourth Line Chemotherapy with Docetaxel for Malignant Pleural Mesothelioma (MPM) Michaela Kirschner, University Hospital Zurich, Switzerland PP01.20: Tumor-Infiltrating Lymphocytes and BAP-1, VEGFR-2, IGF-1R Expression in Malignant Pleural Mesothelioma Mir Hoda, Medical University of Vienna, Austria PP01.19: Combining Cell-Free microRNAs and SMRP: A Multi-Biomarker Signature with Improved Diagnostic Accuracy PP01.26: Initial Results of the Multicentric Turkish Malignant Pleural Mesothelioma Database* Mariana Abal, Instituto Oncologico Henry Moore, Argentina 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 Nobukazu Fujimoto, Okayama Rosai Hospital, Japan PP01.35: Malignant Pleural Mesothelioma in Patients Older than 45 Years Fatma Aou El-Kasem, National Cancer Institute, Egypt PP01.36: A Mesothelioma Cluster Amongst Experimental Physicists Steven Kazan, Kazan McClain Satterley & Greenwood, USA PP01.37: Survival in Good Performance Malignant Pleural Mesothelioma Patients; Prognostic Factors and Predictors of Response Hala Aziz Shokralla, National Cancer Institute, Egypt PP01.38: Non-Epithelial Pleural Mesothelioma; Criteria, Prognostic Factors and Predictors of Response Hala Aziz Shokralla, National Cancer Institute, Egypt PP01.39: Does Pretreatment Body Weight Have Any Significant Impact on Survival in Pleural Mesothelioma in Young Age Group? Hala Aziz Shokralla, National Cancer Institute, Egypt PP01.40: Malignant Pleural Mesotheliom: A Single-Center Experience in Croatia Marko Jakopovic, University Hospital Center Zagreb, Croatia PP01.41: Mesothelioma Incidence in Lombardy, Italy: Time Patterns and Future Projections PP01.42: Clinico Pathological Characteristics of Young Egyptian Malignant Pleural Mesothelioma Patients Fatma Aou El-Kasem, National Cancer Institute, Egypt PP01.43: Increasing Age at Diagnosis in the Australian Malignant Pleural Mesothelioma Population: What Are the Potential Implications? Matthew Soeberg, Asbestos Diseases Research Institute, Australia PP01.44: Study on the Evolution over Time of the Risk of Mesothelioma and Lung Cancer among Former Asbestos-Exposed Workers Corrado Magnani, University Eastern Medicine, Italy PP01.46: Mortality/Hospitalization From Pleural Mesothelioma Associated With Environmental Exposure to FluoroEdenite in Biancavilla MONDAY, MAY 2 PP01.34: Brain Metastases in Malignant Pleural Mesothelioma Susanna Conti, Istituto Superiore di Sanità, Italy PP01.47: Survival and Expected Years of Life Lost of Malignant Mesothelioma: Analysis of 105 Cases in Taiwan, 1977-2015 Lukas Lee, National Health Research Institutes, Taiwan PP01.50: Investigating Palygorskite’s Role in the Development of Mesothelioma in Southern Nevada Michele Carbone, University of Hawaii Cancer Center, USA PP01.51: Mesothelioma Mortality in Poland Between 1999 and 2013 Anna Minkiewicz, Medical University of Warsaw, Poland Dario Consonni, Fondazione IRCCS Ca’ Granda - Ospedale Maggiore Policlinico, Italy iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 15 MONDAY, MAY 2 PP01.62: Malignant Pleural Mesothelioma in Austria: Data from the Austrian Mesothelioma Interest Group Database MONDAY, MAY 2 PP01.52: Relationship between Histological Type and Pleural Effusion in Malignant Pleural Mesothelioma Koji Mikami, Hyogo College of Medicine, Japan PP01.53: Pattern Of Malignant Pleural Mesothelioma in Egyptian Patients PP01.63: Histopathological Reporting of Mesothelioma Resection Specimens Fatma Aou El-Kasem, National Cancer Institute, Egypt PP01.54: Asbestos Consumption and Pleural Mesothelioma Mortality in Poland in Comparison with Other European Countries David Moore, University Hopsitals Leicester NHS Trust, United Kingdom PP01.64: Inherited Predisposition to Malignant Mesothelioma Anna Minkiewicz, Medical University of Warsaw, Poland Irma Dianzani, Interdepartmental Center for Studies on Asbestos and other Toxic Particulates “G. Scansetti”, Italy PP01.56: Blood DNA Methylation Changes in Malignant Pleural Mesothelioma PP01.65: Characterization of Intertumor Heterogeneity in Malignant Mesothelioma Elisabetta Casalone, Human Genetics Foundation and University of Turin, Italy PP01.57: Malignant Pleural Mesothelioma in Africa Gill Nelson, University of Witwaterrand, South Africa Noushin Nabavi, Vancouver Prostate Centre, Canada PP01.66: Pathology Analysis for Mesothelioma Study in the United Kingdom: Current Practice and Historical Development Bruce Case, McGill University, Canada PP01.59: Malignant Pleural Mesothelioma Long Term Survivors: A Population Based Study (LUME Study) PP01.67: Variations in Copy Number in the Malignant Pleural Mesothelioma Genome Valeria Ascoli, Oncological and AnatomoPathological Sciences, Sapienza University, Italy PP01.60: Epidemiology of Mesothelioma in Southern Brazil: A Reality Still to Be Studied Dario Consonni, Fondazione IRCCS Ca’ Granda - Ospedale Maggiore Policlinico, Italy PP01.61: Malignant Pleural Mesothelioma in Young People Ahmed El Bastawisy, National Cancer Institute, Egypt Marieke Hylebos, Center for Oncological Research, University of Antwerp, Belgium PP01.68: Homozygous 9p21 (p16/CDKN2A) Deletion in Mesothelioma–5 Year Retrospective Specialist Diagnostic Pleural Pathology Audit Lauren Harries, University Hospital of South Manchester, United Kingdom PP01.69: Mutation Status and Expression of the microRNA-Processing RibonucleaseIII Dicer1 in Malignant Pleural Mesothelioma 16 Mir Hoda, Medical University of Vienna, Austria Eric Santoni-Rugiu, Copenhagen University Hospital, Denmark 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG MONDAY, MAY 2 Sophie Sneddon, National Centre for Asbestos Related Diseases, The University of Western Australia, Australia PP01.71: Mutational Burden and CDKN2A Status as a Robust Outcome Predictor for Radical Surgery in Mesothelioma Annabel Sharkey, University of Leicester, United Kingdom PP01.72: Whole-Genome Dna Methylation and Transcriptome Changes in Asbestos Exposed met5a Cells Elisabetta Casalone, Human Genetics Foundation and University of Turin, Italy PP01.73: Genomic Interrogation of a Clonal Recurrence of Pleural Mesothelioma 12.5 Years After Radical Surgery Annabel Sharkey, University of Leicester, United Kingdom PP01.77: A Systematic Investigation of the Maximum Tolerated Dose of Cytotoxic Chemotherapy with Supportive Care in Mice Willem Lesterhuis, National Centre for Asbestos Related Diseases, The University of Western Australia, Australia PP01.78: Cancer Chemo Immunotherapy Exploiting the Immunogenic Potential of Cyclophosphamide MONDAY, MAY 2 PP01.70: A Comparison of the Genetic Characteristics of Murine and Human Malignant Mesothelioma Willem Lesterhuis, National Centre for Asbestos Related Diseases, The University of Western Australia, Australia PP01.79: Identification of Repurposed Drugs That Increase Immune Checkpoint Blockade Efficacy in Mesothelioma Using Network Analysis of Responding Tumours Willem Lesterhuis, National Centre for Asbestos Related Diseases, The University of Western Australia, Australia PP01.74: CDKN2A Deletion: A Clonal Mutation in Malignant Pleural Mesothelioma Development? Luke Martinson, University of Leicester, United Kingdom PP01.75: Update: Recent Studies Examining Impact of BAP1 Mutation on Mesothelioma Risk and Implications for Mesothelioma Litigation Steven Kazan, Kazan McClain Satterley & Greenwood, USA PP01.76: BAP1 Value in Diagnosis Michele Carbone, University of Hawaii Cancer Center, USA iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 17 TUESDAY, MAY 3, 2016 EARLY INTERVENTIONS 08:00 – 08:45 10:20 PL03.04: Final Q & A ISS01: Industry-Supported Symposium Hall 9 For the detailed programme please refer to page 49. 10:30 – 11:15 Networking Break and Poster Viewing Hall 3 09:00 – 10:30 PL03: Plenary Session III: The Knife or the Needle? Chairs: Najib Rahman, United Kingdom & David Waller, United Kingdom & Seiki Hasegawa, Japan Hall 1 18 09:00 PL03.01: The Evidence for Surgery Joseph Friedberg, University of Maryland School of Medicine, USA 11:15 – 12:45 PL04: Plenary Session IV: From Genetics to Therapy Chairs: Richard Lake, Australia & Harvey Pass, USA & Paul Baas, Netherlands Hall 1 11:15 PL04.01: Matching Drugs with Genes Ultan McDermott, Wellcome Trust Sanger Institute, United Kingdom 11:35 PL04.02: The Therapeutic Link Between BAP1 and EZH2 Lindsay Lafave, Memorial Sloan Kettering Cancer Center, USA 11:55 PL04.03: Phase 1 Study of Tazemetostat (EPZ-6438), an Inhibitor of EZH2, in Patients with NonHodgkin Lymphoma and Solid Tumors 09:20 PL03.02: The Evidence for Chemotherapy Jan Van Meerbeeck, University Hospital Antwerp, Belgium 09:40 PL03.03: Debate: What Would You Do First in Early Stage MPM Surgery or Chemotherapy? Isabelle Opitz, University Hospital Zürich, Switzerland David Rice, MD Anderson Cancer Center, USA Peter Ho, Epizyme Inc., USA Raja Flores, Mount Sinai Health System, USA 12:05 Peter Szlosarek, Barts Cancer Institute & St. Bartholomew’s Hospital, United Kingdom PL04.04: From Chaotic to Specific Genomic Alterations Sakari Knuutila, University of Helsinki, Finland Rolf Stahel, University Hospital Zürich, Switzerland Arnaud Scherpereel, Hospital of the University (CHU) of Lille, France 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG TUESDAY, MAY 3 PL04.05: Differential Response of Malignant Pleural Mesothelioma Cells to Yap Targeted Therapy According to Molecular Classification 14:25 MS09.02: A New Prognostic Score for Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma - An Update Robin Tranchant, INSERM U.1162, France Isabelle Opitz, University Hospital Zürich, Switzerland 12:35 PL04.06: Novel Synergistic Cell Therapies for the Treatment of Malignant Pleural Mesothelioma 14:35 MS09.03: Group Discussion Consensus on Patient Selection Krishna Kolluri, University College London, United Kingdom 14:45 MS09.04: It’s Never Too Late To Operate - An Analysis Of Salvage Surgery For Progressing Malignant Pleural Mesothelioma Annabel Sharkey, University Hospitals of Leicester, United Kingdom 14:55 MS09.05: Group Discussion Consensus on Timing of Surgery 15:05 MS09.06: Evolution of Surgical Approach in Malignant Pleural Mesothelioma Seiki Hasegawa, Hyogo College of Medicine, Japan 15:15 MS09.07: When Is Extrapleural Pneumonectomy Necessary? Walter Weder, University Hospital Zürich, Switzerland 15:25 MS09.08: The Role of Pleurectomy/ Decortication in the Mesothelioma Risk-Benefit Equation Raja Flores, Mount Sinai Health System, USA 15:35 MS09.09: Group Discussion Technical Points of Importance to Obtain a Macroscopic Complete Resection 12:45 – 14:15 Networking Break and Poster Viewing Hall 3 13:15 – 14:15 ISS02: Industry-Supported Symposium Hall 9 For the detailed programme please refer to page 49. 14:15 – 15:45 MS09: Mini Symposium 9: Surgery (Technical Aspects) Chairs: Walter Weder, Switzerland & David Waller, United Kingdom Hall 6 14:15 MS09.01: Extended PleurectomyDecortication for Pleural Mesothelioma in the Elderly - the Need for an Inclusive yet Selective Approach TUESDAY, MAY 3 12:25 Annabel Sharkey, University Hospitals of Leicester, United Kingdom iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 19 TUESDAY, MAY 3 14:15 – 15:45 TUESDAY, MAY 3 MS10: Mini Symposium 10: Novel Targets – Entering in the Clinic Chairs: Hedy Kindler, USA & Sanjay Popat, United Kingdom 14:15 20 Hall 9 MS10.01: Phase I Study of AntiMesothelin Antibody Drug Conjugate Anetumab Ravtansine in Patients with Metastatic Mesothelioma Raffit Hassan, National Cancer Institute, USA 14:25 MS10.02: Phase 1 Dose Expansion Experience of ADI-PEG20, Pemetrexed and Cisplatin in Patients with Malignant Mesothelioma (TRAP Study) Peter Szlosarek, Barts Cancer Institute, United Kingdom 14:35 MS10.03: Tremelimumab and Durvalumab Combination for First and Second-Line Treatment of Mesothelioma Patients: The NIBITMESO-1 Study 15:05 MS10.06: Oncolytic Herpesvirus Therapy for Mesothelioma - a Phase I/IIa Trial of Intrapleural HSV1716 (NCT01721018) Kevin Blyth, Queen Elizabeth University Hospital, United Kingdom 15:15 MS10.07: A Phase I Clinical Trial of HVJ-Derived Nanoparticle for Chemotherapy-Resistant Malignant Pleural Mesothelioma Chunman Lee, Osaka University, Japan 15:25 MS10.08: Discussion 14:15 – 15:45 MS11: Mini Symposium 11: Critical Signaling Pathway Chairs: Yoshitaka Sekido, Japan & Daniel Murphy, United Kingdom & Anne Tsao, USA Hall 10a 14:15 MS11.01: Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth in Vivo by Affecting Stroma Luana Calabro, University Hospital of Siena, Italy Mayura Meerang, University Hospital Zurich, Switzerland 14:45 MS10.04: Phase 2 Neoadjuvant Study of VS-6063, a FAK Inhibitor, in Subjects with Surgically Resectable Malignant Pleural Mesothelioma 14:25 MS11.02: SIRT1 at the Crossroads of AKT1 and ERβ in Malignant Pleural Mesothelioma Cells Raphael Bueno, Brigham and Women’s Hospital and Harvard Medical School, USA Laura Moro, University of Piemonte Orientale, Italy 14:35 MS11.03: Evaluation of Sensitivity to PI3K/mTOR and FAK Inhibition in Pre-Clinical Models of Malignant Mesothelioma Ian Powley, MRC Toxicology Unit, United Kingdom 14:55 MS10.05: Phase I Experience with TargomiRs in Malignant Pleural Mesothelioma Nico Van Zandwijk, Asbestos Diseases Research Institute, Australia 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG 14:45 MS11.04: Identifying MicroRNAs With Therapeutic Potential in Malignant Pleural Mesothelioma Glen Reid, Asbestos Diseases Research Institute, Australia 14:55 MS11.05: MicroRNA-31 Regulates Chemosensitivity in Malignant Pleural Mesothelioma via Altered Intracellular Drug Localisation Hannah Moody, Hull York Medical School, United Kingdom 15:05 MS11.06: Targeting the Rate-Limiting Step of Protein Synthesis Overcomes Chemoresistance in Malignant Mesothelioma Stefano Grosso, MRC Toxicology Unit, United Kingdom 15:15 MS11.07: The Role of Monocyte Chemotactic Protein-1 (MCP-1) in Mesothelioma-Induced Malignant Pleural Effusion Formation Sally Lansley, Institute for Respiratory Health, Australia 15:25 MS11.08: Final Q & A 14:25 MS12.02: Simultaneous Care (SimC) in Mesothelioma (MM): A Dedicated Team to Prevent Urgent and Unplanned Hospital Admissions Federica Grosso, SS. Antonio e Biagio e C. Arrigo, Hospital, Italy 14:35 MS12.03: Open Discussion Session 15:10 MS12.04: Final Q & A 15:45 – 16:30 Networking Break and Poster Viewing Hall 3 16:30 – 18:00 MS13: Mini Symposium 13: Genomics and Drug Sensitivity Chairs: Ultan McDermott, United Kingdom & Marc Ladanyi, USA TUESDAY, MAY 3 TUESDAY, MAY 3 Hall 10a 16:30 MS13.01: The MexTAg Collaborative Cross: Identifying the Genetic Basis of Mesothelioma MS12: Mini Symposium 12: Treatment Advances in Peritoneal Mesothelioma / Palliative Care for All Mesothelioma Scott Fisher, National Centre for Asbestos Related Diseases, Australia 16:40 Chairs: Jeremy Steele, United Kingdom & Helen Clayson, United Kingdom MS13.02: Translational Control of MPM: Role of eIf6 and MicroRNAs in Metabolism Stefania Oliveto, INGM - Fondazione Istituto Nazionale Genetica Molecolare “Romeo ed Enrica Invernizzi”, Italy 16:50 MS13.03: BAP1 Knockout by CRISPRCas9 Genome Editing in Malignant Pleural Mesothelioma Cell Lines for Isogenic Functional Studies Julija Hmeljak, Memorial Sloan Kettering Cancer Center, USA 14:15 – 15:45 Hall 10b 14:15 MS12.01: Gender and Menopausal Status: Survival in Peritoneal Mesothelioma Gleneara Bates, Columbia University Medical Center, USA iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 21 TUESDAY, MAY 3 MS13.04: BAP1 Expression and Impact on Treatment Outcomes in Malignant Pleural Mesothelioma in a Prospective UK Based Clinical Trial 16:50 MS14.03: Overcoming Radiation Resistance of Mesothelioma by Activating Tumour Specific Cell Death Neelam Kumar, University College London, United Kingdom Lesley Gilmour, University of Glasgow, United Kingdom 17:10 MS13.05: Relationship of PD-L1 Expression and Prognosis in Epithelioid Mesothelioma 17:00 MS14.04: Synergistic Effect of Local Radiation Therapy and Immunotherapy in a Mouse Model of MPM Tohru Tsujimura, Hyogo College of Medicine, Japan Luis De La Maza-Borja, University Health Network, Canada 17:20 MS13.06: Systems Biology Approaches Towards Developing Personalized Cancer Therapies for Malignant Pleural Mesothelioma (MPM) 17:10 MS14.05: The SMART Trial - an RCT of Prophylactic Radiotherapy in Preventing Procedure Tract Metastases in Mesothelioma Marija Krstic-Demonacos, University of Salford, United Kingdom Nick Maskell, University of Bristol, United Kingdom 17:30 MS13.07: Final Q & A 17:20 MS14.06: Final Q & A TUESDAY, MAY 3 17:00 16:30 – 18:00 MS14: Mini Symposium 14: Radiotherapy Chairs: Noelle O’Rourke, United Kingdom & Andreas Rimner, USA 16:30 – 18:00 MS15: Mini Symposium 15: Multimodality Chairs: Paul Baas, Netherlands & Raphael Bueno, USA Hall 6 Hall 10b 22 16:30 MS15.01: Combined Modality Treatment Using Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma: A Single Centre Experience Keith Cengel, University of Pennsylvania, USA Philippe Nafteux, KU Leuven-University of Leuven, Belgium 16:40 MS14.02: SYSTEMS-2:Randomised Phase II Trial of Standard versus Dose Escalated Radiotherapy for Pain in Malignant Pleural Mesothelioma 16:40 MS15.02: Outcome of Trimodality Therapy including Intracavitary Hydrogen Peroxide Treatment in Malignant Pleural Mesothelioma Miranda Ashton, Beatson West of Scotland Cancer Centre, United Kingdom Mir Hoda, Medical University of Vienna, Austria 16:30 MS14.01: Examining Signaling Pathway Crosstalk in Mesothelioma PDT and RT Sensitivity Using 2D and Novel 3D Tissue Culture Models 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG TUESDAY, MAY 3 MS15.03: Cytoreductive Surgery and Hyperthermic Intrathoracic Chemotherapy for Treatment of Pleural Mesothelioma: A 10-Year Experience 16:30 MS16.01: Blockade of Protein Kinase A (PKA) Localization Augments Trafficking And Anti-Tumor Efficacy Of CAR T cells Pietro Bertoglio, U.O. Chirurgia Toracica, Italy Edmund Moon, University of Pennsylvania, USA 17:00 MS15.04: Radical Pleurectomy and Hyperthermic Intrathoracic Chemoperfusion for the Treatment of Malignant Pleural Mesothelioma 16:40 MS16.02: Characterising T-Cell Responses against Mutated Mesothelioma Neo-Antigens Bruce Robinson, University of Western Australia, Australia Laura Klotz, Center for Thoracic Surgery Munich, Germany 16:50 17:10 MS15.05: Intracavitary CisplatinFibrin Application Following Resection of Mesothelioma MS16.03: CSF1R-Blockade Synergizes with Dendritic Cell Immunotherapy in a Mesothelioma Preclinical Model Isabelle Opitz, University Hospital Zürich, Switzerland Floris Dammeijer, Erasmus Medical Center, Netherlands 17:20 MS15.06: Pleurectomy / Decortication and Intraoperative Intrapleural Hyperthermic CDDP Perfusion for Malignant Pleural Mesothelioma 17:00 MS16.04: Prostaglandin E2-cAMPAdenosine Nexus in Mesothelioma; Self Amplifying Immunosuppression? Zsuzsanna Tabi, Cardiff University, United Kingdom 17:10 MS16.05: Heterotypic 3D Spheroid Tumour Modeling of Mesothelioma to Determine Immune Resistance Saly Al-Taei, Cardiff University, United Kingdom 17:20 MS16.06: Immune Escape Correlates Strongly with an Inflamed Phenotype in Malignant Mesothelioma Yi-Hung Carol Tan, University of Chicago, USA 17:30 MS16.07: Exploiting Immune Checkpoint Blockade to Develop Effective Therapy for Malignant Mesothelioma Scott Fisher, National Centre for Asbestos Related Diseases, Australia 17:40 MS16.08: Final Q & A Kenichi Okubo, Tokyo Medical and Dental University, Japan 17:30 MS15.07: HIPEC as a Treatment for Malignant Peritoneal Mesothelioma: Are We There Yet? Gleneara Bates, Columbia University Medical Center, USA 17:40 MS15.08: Final Q & A 16:30 – 18:00 MS16: Mini Symposium 16: Novel Immune Strategies Chairs: Bruce Robinson, Australia & Joachim Aerts, Netherlands & Dan Sterman (USA) Hall 9 iMig2016.ORG TUESDAY, MAY 3 16:50 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 23 TUESDAY, MAY 3 18:00 – 19:30 PP02: Poster Mixer with Poster Discussions 2 TUESDAY, MAY 3 Moderators: David Waller, United Kingdom & Noelle O’Rourke, United Kingdom & Takashi Nakano, Japan & Peter Szlosarek, United Kingdom & Paul Baas, Netherlands & Ian Woolhouse, United Kingdom & Rabab Gaafar, Egypt & Mary Hesdorffer, USA & Robert Rintoul, United Kingdom & Sanjay Popat, United Kingdom & Gary Middleton, United Kingdom Hall 3 PP02.01: Art and Science: Relationship with Human Anatomy from Aesthetic and Scientific Perspectives Guillermo Villamizar, FundClas, Colombia PP02.02: Localized Splenic Reoccurrence in Malignant Peritoneal Mesothelioma Yaakov Bressler, Columbia University Medical Center, USA PP02.03: Radiological Features of Pleural Mesothelioma Compared with Cases Diagnosed before and after 2008 in Japan Katsuya Kato, Kawasaki Medical School, Japan PP02.05: Asbestos Body and Pleural Plaque of Patients with Malignant Pleural Mesothelioma Who Underwent Extrapleural Pneumonectomy 24 Kazunori Okabe, Yamaguchi Ube Medical Center, Japan Vincent Lam, University Hospitals of Leicester, United Kingdom PP02.07: Patterns of Detectable Tumor Progression in Patients with Malignant Pleural Mesothelioma with an FDG-PETNegative T1a Tumor Kozo Kuribayashi, Hyogo College of Medicine, Japan PP02.08: Lymphangitic Carcinomatosis: A Common Form of Progression in Malignant Pleural Mesothelioma Following Radical Pleurectomy Ian Berger, University of Pennsylvania, USA PP02.09: Malignant Pleural Mesothelioma, Demographic Data and Clinical Staging of 193 Consecutive Patients Amr Eldemery, National Cancer Institute, Egypt PP02.10: Into the Deep: Closer Look at Immune Cells and Immune Checkpoint Expression in Human Malignant Pleural Mesothelioma Takumi Kishimoto, Okayama Rosai Hospital, Japan PP02.04: CT Findings of Malignant Pleural Mesothelioma and Correlation with the Survival Period PP02.06: The Imaging Journey of a Patient with Malignant Mesothelioma Elly Marcq, Center for Oncological Research, University of Antwerp, Belgium PP02.11: Development of Novel Therapeutics Targeting Malignant Pleural Mesothelioma Perry Devo, University of Greenwich, United Kingdom PP02.12: Inhibition of Methyltransferase EZH2 Improves Tumoricidal Activity of Macrophages against Mesothelioma Cells Malik Hamaidia, Interdisciplinary Cluster for Applied Genoproteomics (GIGA) of University of Liège, Belgium 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG TUESDAY, MAY 3 PP02.21: Focal Adhesion Kinase Inhibition Targets Macrophages in vitro and in vivo in a Mesothelioma Mouse Model Carmelina Iannuzzi, University of Siena, Italy PP02.14: Characterising CTL Responses against Mesothelioma Neo-Antigens Bruce Robinson, University of Western Australia, Australia PP02.22: Pleural Effusion of Patients with Malignant Mesothelioma Induces Macrophage-Mediated T Cell Suppression PP02.15: Gene Profile of Mesothelioma Tumorigenesis and Initiation after Chemoradiation Treatment in vitro and in vivo Models Licun Wu, Toronto General Hospital and Princess Margaret Cancer Center, Canada PP02.16: The Elevated Levels of G-MDSC in Mesothelioma Patients Inhibit T Cell Proliferation and Function by ROS Generation Licun Wu, Toronto General Hospital and Princess Margaret Cancer Center, Canada Scott Fisher, National Centre for Asbestos Related Diseases. The University of Western Australia, Australia PP02.27: Legal Claims for Asbestosis in the Netherlands Possible since 2014: How It Works Wanda Hagmolen Of Ten Have, Radboudumc, Netherlands PP02.28: Evaluation of Curcumin i.p. For the Treatment of Sarcomatoid Mesothelioma, Experimental Study on a Rat Model Daniel Pouliquen, UMR 892 INSERM / 6299 CNRS, France PP02.29: Biphasic Pleural Mesothelioma: Unusual Clinical Behavior Abdulhadi Almutairi, King Fahad Specialist Hospital, Saudi Arabia PP02.30: MARS 2: A Feasibility Study Comparing (Extended) Pleurectomy Decortication versus No Pleurectomy Decortication iMig2016.ORG Alistair Cook, The University of Western Australia, Australia PP02.26: Targeted Depletion of Regulatory T Cells in Mesothelioma Matthew Wu, University Health Network, Canada PP02.19: Immunophenotype of a Novel Murine Mesothelioma Cell Line RN5 and Specific Immunity Generated by Pulsation with Cell Lysate Adrian Dobbs, University of Greenwich, United Kingdom PP02.18: HMGB-1 Release and the CD8+ T Cell Response Elicited by Radiation Treatment in Malignant Pleural Mesothelioma Lysanne Lievense, Erasmus MC Cancer Institute, Netherlands PP02.23: The Abscopal Effect of Radiotherapy in the Context of Checkpoint Blockade in a Mouse Mesothelioma Model Raffit Hassan, National Cancer Institute, USA PP02.17: Novel Medicinal Chemistry Approaches in Mesothelioma: The Role of Natural Products Lysanne Lievense, Erasmus MC Cancer Institute, Netherlands TUESDAY, MAY 3 PP02.13: The Dl 922-947 Oncolytic Virus as a New Possible Therapeutic Tool against Mesothelioma Eric Lim, Royal Brompton Hospital, United Kingdom 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 25 TUESDAY, MAY 3 PP02.39: Does Open Access Expert Phone Triage Based on 2012 IMiG Guidelines for Veterans Receiving Care within the VA, Alter Therapy? TUESDAY, MAY 3 PP02.31: MesoTRAP: A Feasibility Study of Indwelling Pleural Catheter versus VAT Pleurectomy for Trapped Lung in Mesothelioma Robert Rintoul, Papworth Hospital NHS Foundation Trust, United Kingdom PP02.32: LUME-Meso: A Placebo-Controlled Phase II/III Study of Nintedanib + Pemetrexed/Cisplatin Followed by Maintenance Nintedanib Sanjay Popat, Royal Marsden Hospital NHS Foundation Trust, United Kingdom PP02.33: Autologous Dendritic Cell Immunotherapy Loaded with an Allogenic Tumor Cell Lysate in Patients with Mesothelioma Joachim Aerts, Erasmus MC Cancer Institute, Netherlands PP02.34: Randomised Phase II Trial of Vinorelbine as 2nd-Line Therapy for Patients with Malignant Pleural Mesothelioma - VIM Trial Lisette Nixon, Cardiff University, United Kingdom PP02.35: A Randomized Study of Amatuximab with Pemetrexed and Cisplatin as FrontLine Therapy for Subjects with Pleural Mesothelioma Bruce Wallin, Morphotek, Inc, USA PP02.36: Switch-Maintenance with Gemcitabine for Patients with Malignant Mesothelioma: Feasibility of a Randomized Phase II Study Josine Quispel-Janssen, Netherlands Cancer Institute, Netherlands PP02.37: MESOCLIN: A French National Network of Expert Centers for the Management of MPM Patients and for Research Promotion 26 Abraham Lebenthal, Brigham and Women’s Hospital, USA PP02.41: MINE PROJECT - Mesothelioma Information Network in Europe Corrado Magnani, University Eastern Medicine, Italy PP02.42: Personalised Support for Patients with Malignant Pleural Mesothelioma (MPM) in New South Wales, Australia Jocelyn McLean, Asbestos Diseases Research Institute, Australia PP02.43: Surgical Cytoreduction and Hyperthermic Intrathoracic Chemotherapy (HITHOC) for Malignant Pleural Mesothelioma Michael Ried, University Medical Center Regensburg, Germany PP02.44: Diode-Pumped Nd:YAG Laser for LungSparing Surgical Treatment of Malignant Pleural Mesothelioma - First Experience Servet Bölükbas, Helios Klinikum Wuppertal, Germany PP02.45: Pathological Evaluation of the Visceral Pleura Stamp in the Radical Pleurectomy/Decortication for MPM Patients Masashi Kobayashi, Tokyo Medical and Dental University, Japan PP02.46: Clinical and Immunologic Impact of Surgery for Malignant Pleural Mesothelioma Vincenzo Ambrogi, Tor Vergata University, Italy Arnaud Scherpereel, Hospital of the University (CHU) of Lille, France 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG PP02.47: Who Benefits From Macroscopic Complete Resection In Malignant Pleural Mesothelioma? PP02.54: Analysis of Gene-Expression Changes in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma Hasan Batirel, Marmara University Faculty of Medicine, Turkey PP02.48: Is Surgery For Mesothelioma In The UK A Dying Modality In The Management Of Malignant Mesothelioma? Update on our Experience PP02.55: Myosin II-Dependent Cell Contractility Drives Spontaneous Nodule Formation of Mesothelioma Cells Mohammed Khalil, Castle Hill Hospital, United Kingdom PP02.49: The Analysis of the Recurrence of the Patients Who Underwent Surgical Resection for Malignant Pleural Mesothelioma Nobuyuki Kondo, Hyogo College of Medicine, Japan Courtney Broaddus, University of California San Francisco, USA Julia Tarnoki-Zach, Eotvos Lorand University, Hungary PP02.56: Post-Transcriptional Regulation of Calretinin Expression Jelena Kresoja-Rakic, University of Zürich, Switzerland PP02.57: Identification of Cis- and TransActing Elements Regulating Calretinin Expression in Mesothelioma Cells PP02.50: Ipsilateral Pneumonectomy after Pleurectomy/Decortication in a Patient with Malignant Pleural Mesothelioma PP02.58: Decreased Proliferation and Cell Migration of Primary Mesothelial Cells from Calretinin-Deficient (CR-/-) Mice Toru Nakamichi, Hyogo College of Medicine, Japan Jelena Kresoja-Rakic, University of Zürich, Switzerland PP02.51: Induction Chemotherapy Followed by Surgery for Malignant Pleural Mesothelioma PP02.59: KCNMA1 Is Targeted by miR-17-5p and Modulates Cell Migration in Malignant Pleural Mesothelioma Nobuyuki Kondo, Hyogo College of Medicine, Japan Walter Blum, University of Fribourg, Switzerland PP02.52: Anti-Tumor Effects of Metformin and Nutlin-3a in Malignant Pleural Mesothelioma PP02.60: Engineered, Light-Controlled Growth Factor Receptors for Mesothelioma Research Yuji Tada, School of Medicine Chiba University, Japan Yuen Yee Cheng, Asbestos Diseases Research Institute, Australia PP02.53: Compared High-Resolution Whole Genome Screening of Mesothelioma and Benign Asbestos Pleurisy PP02.61: Preclinical Investigation of the Therapeutic Potential of Nintedanib in Malignant Pleural Mesothelioma Tunç Tuncel, Eskisehir Osmangazi University, Turkey iMig2016.ORG TUESDAY, MAY 3 TUESDAY, MAY 3 Michael Grusch, Medical University of Vienna, Austria Viktoria Laszlo, Medical University of Vienna, Austria 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 27 TUESDAY, MAY 3 PP02.69: Trabectedin Is Active as Single Agent and Synergizes with Chemotherapy and Bcl-2 Inhibition in Malignant Pleural Mesothelioma TUESDAY, MAY 3 PP02.62: Comparative Analysis of 4 Experimental Mesotheliomas in F344 Rats: A Preliminary Study of Their Tumor Biology Features Joëlle Nader, UMR 892 INSERM / 6299 CNRS, France PP02.63: THBS2, a Novel Gene Involved in the Malignant Progression of Pleural Mesothelioma PP02.70: Live Cells Mesothelioma Biobank to Explore Mechanisms of Tumor Progression Elisa Barone, University of Pisa, Italy PP02.64: Growth Factor-Induced Morphology and Expression Changes in Cell Models Reflecting the Histological Mesothelioma Subtypes Masatoshi Tagawa, Chiba Cancer Center Research Institite, Japan PP02.67: Shed Syndecan-1 Alters Angiogenesis in Malignant Mesothelioma Katalin Dobra, Karolinska Institutet, Sweden PP02.68: Utilising MicroRNAs to Sensitise Mesothelioma to Cisplatin and Gemcitabine Antonios Sideris, Brigham and Women’s Hospital and Harvard Medical School, USA PP02.72: Cell Assays and SAXS Indicate That BAMLET Is a Potential Treatment for Chemotherapy-Resistant Mesothelioma Giulia Pinton, University of Piemonte Orientale, Italy PP02.66: Combination of Nutlin-3a and HSP90 Inhibitors Produces Synergistic Cytotoxicity on Mesothelioma with the Wild-Type p53 Emanuela Felley-Bosco, Zürich University Hospital, Switzerland PP02.71: Analysis of Novel RHOA Mutations in Malignant Pleural Mesothelioma Michael Grusch, Medical University of Vienna, Austria PP02.65: The H3K27me3 Demethylase KDM6B as an Epigenetic Regulator of ER? Expression in Human Malignant Pleural Mesothelioma 28 Mir Hoda, Medical University of Vienna, Austria Glen Reid, Asbestos Diseases Research Institute, Australia PP02.73: Tumour Suppressor microRNA-137-3p Targets Onco-Protein YB-1 in Malignant Pleural Mesothelioma Thomas Johnson, Asbestos Diseases Research Institute, Australia PP02.74: IFN Regulatory Factor 9 Play Key Role in Mesothelioma Growth Yidan Zhao, University Health Network, Canada PP02.75: Pro-Oncogenic Effects of Pathogenic Fibres on Mesothelial Cells Joaquin Zacarias-Cabeza, MRC Toxicology Unit, United Kingdom Yuen Yee Cheng, Asbestos Diseases Research Institute, Australia 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG TUESDAY, MAY 3 Hannah Ball, Oxford University Hospitals NHS Foundation Trust, United Kingdom PP02.77: “Around Australia in 80 Days” Judy Rafferty, Canberra Hospital/Lung Foundation Australia, Australia iMig2016.ORG TUESDAY, MAY 3 PP02.76: ‘Are the Psychological Needs of Patients with Mesothelioma the Same as Those with Advanced Lung Cancer?’ 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 29 WEDNESDAY, MAY 4, 2016 NOVEL TREATMENT STRATEGIES & PALLIATION 08:00 – 08:45 10:00 PL05.05: Randomized Phase II Study of Adjuvant WT1 Vaccine for Malignant Pleural Mesothelioma (MPM) After Multimodality Therapy Marjorie Zauderer, Memorial Sloan Kettering Cancer Center, USA 10:10 PL05.06: Improved Quality of Life in Patients Undergoing Pleurectomy and Decortication for Malignant Pleural Mesothelioma Wickii Vigneswaran, Loyola University Medical Center, USA 10:20 PL05.07: Final Q & A ISS03: Industry-Supported Symposium Hall 6 For the detailed programme please refer to page 49. 09:00 – 10:30 PL05: Plenary Session V: What is in the Locker Now? Chairs: Craig Stevens, USA & Takashi Nakano, Japan & Hedy Kindler, USA Hall 1 09:00 Andreas Rimner, Memorial Sloan Kettering Cancer Center, USA 09:10 PL05.02: Pneumonitis Predictors in Intensity Modulated Radiation Treatment of Mesothelioma Patients with Two Lungs 30 PL05.01: Phase II Study on Intensity Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma: Final Results Andrew Jackson, Memorial Sloan Kettering Cancer Center, USA 09:20 PL05.03: Novel Combinations plus Chemotherapy Arnaud Scherpereel, Hospital of the University (CHU) of Lille, France 09:40 PL05.04: State of the Art Approach to Fluid Management Nick Maskell, University of Bristol, United Kingdom 10:30 – 11:15 Networking Break and Poster Viewing Hall 3 11:15 – 12:45 PL06: Plenary Session VI: The “Immune War” on Mesothelioma Chairs: Ken O’Byrne, Australia & Luciano Mutti, United Kingdom & Rabab Gaafar, Egypt Hall 1 11:15 PL06.01: Targeting Mesothelin Raffit Hassan, National Cancer Institute, USA 11:30 PL06.02: “Programmed to Kill” (CellBased Therapy) Joachim Aerts, Erasmus Medical Center, Netherlands 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG WEDNESDAY, MAY 4 PL06.03: Tartgeting Mutations to Penetrate the Immune Shield 14:10 SS03.03: Career Opportunities: Mentoring New Investigators Bruce Robinson, University of Western Australia, Australia Marie-Claude Jaurand, INSERM UMR-S 1162, France 12:00 PL06.04: “Checking It Out” (Immune Checkpoint Blockade) 14:30 Hedy Kindler, University of Chicago Medical Center, USA SS03.04: Open Discussion: New Approaches to Translational Research Discussants: Marion MacFarlane, United Kingdom & Annabel Sharkey, United Kingdom • Current and Future Directions of Mesothelioma Research Bench to Bedside and Back Again • Practical Challenges: e.g. Preclinical Models- in vivo/ex vivo Models, Access to Patient Samples, Bioinformatic Analysis 12:15 PL06.05: The Immune Landscape of Human Mesothelioma to Predict Response to anti-PD1 Therapy Astero Klabatsa, University of Pennsylvania, USA WEDNESDAY, MAY 4 11:45 12:25 PL06.06: Maximizing the “Immune Attack” Anna Nowak, University of Western Australia, Australia • Priority Research Areas for Funders in the Mesothelioma Domain 12:40 PL06.07: Final Q & A 15:00 SS03.05: Networking for Development of New Collaborations and Visits between Labs** Introducing Opportunities Available for up to 3 Months at These Institutions • University of Eastern Piedmont Amedeo Avogadro Laura Moro, Italy • MRC Toxicology Unit Marion MacFarlane, United Kingdom • The University of Western Australia - Anna Novak, Australia • University of California San Francisco - Courtney Broaddus, USA • University of Leicester, CRUK Leicester Centre 12:45 – 13:15 Presidential Closing and Invitation to iMig 2018 Hall 1 13:30 – 15:30 SS03: Young Investigator’s Session* Chair: Sara Busacca, United Kingdom Hall 9 13:30 SS03.01: Career Opportunities: Industry Nikki Roebuck, Clovis Oncology, United Kingdom • INSERM UMR-S 1162, Paris Didier Jean, France • INSERM UMR 892, Nantes Marc Grégoire, France 13:50 SS03.02: Career Opportunities: Clinic & Research Aaron Mansfield, Mayo Clinic, USA *The Scientific Committee welcomes all Young Investigators with a maximum of 10 years of experience. **Visitors should be self-funded. iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 31 INFORMATION FOR INVITED SPEAKERS AND ABSTRACT PRESENTERS SPEAKER READY ROOM The Media Suite at the ICC is the designated Speaker Ready Room. All presenters are required to submit and/or preview their slides at least 3 hours prior to their scheduled presentation to ensure compatibility with the Conference AV Equipment. Computers are available to upload and preview presentations. Speakers are required to report to the Speaker Ready Room at least 3 hours prior to their scheduled presentations. Changes can be made until 90 minutes prior to your presentation. Presenters should make sure all fonts appear as expected and all sound/video clips are working properly. The final version must be submitted to the Speaker Ready Room, no file submissions are accepted in the Session Rooms. Speaker Ready Room Opening Hours Sunday, May 1 16:00 – 19:30 Monday, May 2 07:30 – 17:00 Tuesday, May 3 07:30 – 17:00 Wednesday, May 4 07:30 – 11:00 ORAL ABSTRACT PRESENTERS Oral Abstract Presenters are required to prepare a PowerPoint Presentation for their 10 minute didactic presentation (max. 10 slides including title, author and disclosure slides). Please make sure that you stick to your allocated time. The Conference chair will cut you off after your allocated 10 minutes time slot! 32 POSTER PRESENTERS All Poster Presentations/Boards are located in Hall 3 at the ICC. A sign identifies each Poster Board with the assigned Poster Number and the Presenter’s Name. The Poster Board Number corresponds with the pre-assigned Final Presentation Number provided in your confirmation letter and used in the Abstract Book and this Onsite Programme. Poster Presenters are required to provide a 2 minute presentation of their poster to the invited Poster Moderators during the Poster Mixer and Poster Discussion Session. 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG Please note that Poster Presenters will not be asked to prepare a PowerPoint Presentation. POSTER PRINTING Poster Presenters are able print their posters onsite in the Graphics Studio (around the corner from the Media Suite/Speaker Ready Room). The cost of poster printing is £30.00 per poster plus VAT. Delegates must bring a USB stick with their presentation saved as a print quality PDF. Poster Set-Up Time Sunday, May 1, 2016 16:00 – 18:00 Poster Take-Down Time Wednesday, Monday 4, 2016 12:00 – 14:30 Any posters not removed after Take-Down Time will be removed and discarded by management. Poster Session 1 Monday, Monday 2, 2016 Poster Display Hours: 10:30 – 19:30 Meet the Author: 10:30 – 11:15 12:45 – 14:15 15:45 – 16:30 Mixer and Discussion: 18:00 – 19:30 Poster Session 2 Tuesday, Monday 3, 2016 Poster Display Hours: 10:30 – 19:30 Meet the Author: 10:30 – 11:15 12:45 – 14:15 15:45 – 16:30 Mixer and Discussion: 18:00 – 19:30 Poster Session 3 Wednesday, Monday 4, 2016 Poster Display Hours: Meet the Author: iMig2016.ORG 10:30 – 12:00 10:30 – 11:15 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 33 iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 35 CONFERENCE VENUE CONFERENCE INFORMATION The International Convention Centre (ICC) Broad Street, Birmingham, B1 2EA United Kingdom www.theicc.co.uk FLOOR PLANS All iMig 2016 Conference Session Rooms as well as Exhibits, Posters and Registration are located in the International Convention Centre (ICC) which is linked directly to The Hyatt Regency Birmingham via a covered, secured bridge link walkway. LEVEL 5 EXECUTIVE ROOM 1 iMig BOARDROOM EXECUTIVE ROOM 2 MEETING ROOM LEVEL 4 HALL 3 HALL 1 PLENARY HALL EXHIBITS & POSTERS LUNCH & NETWORKING BREAKS REGISTRATION MEDIA SUITE SPEAKER READY ROOM & MEDIA OFFICE LEVEL 3 HALL 6 SESSION ROOM LEVEL 2 HALL 10A / 10B HALL 9 SESSION ROOMS SESSION ROOM iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 37 GENERAL INFORMATION FROM A TO Z Abstract Book (USB Stick) All accepted and confirmed abstracts are available on the Conference website at www.iMig2016.org and on a USB Stick handed out with your registration materials. International Attendees can request and pick up a ‘Certificate of Attendance’ at Registration during regular registration hours. Please note that registration closes at 11:00 on Wednesday, May 4. SUPPORTED BY Charging Stations Badges Your personalised badge is your admission card to the congress. For organisational and security reasons, badges must be worn at the congress venue at all times. A lanyard will be given to you with the congress bag. In case of loss, a replacement badge will be provided at an administrative charge of £25.00. LANYARDS/BADGE HOLDERS SUPPORTED BY Birmingham Information Maps and a brochure of Birmingham are available at Registration. Cameras and Cell Phones No cameras or video cameras are allowed in any event during iMig 2016. As a courtesy to fellow delegates, please turn off cell phones during scientific sessions. Certificate of Attendance To complete the session evaluation and obtain credits for your attendance at iMig 2016, please use the online evaluation system at iMig2016.org. 38 Charging Stations will be available in the Exhibit Hall (Hall 3) to allow you to take a break while powering your mobile devices. SUPPORTED BY CME Credit Allowance The International Mesothelioma Interest Group (iMig) is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net. iMig 2016 will be accredited with 15 European CME credits (ECMEC) by the European Accreditation Council for Continuing Medical Education (EACCME). Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/ internationalcme. 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG Delegate Help Desk If you require assistance or any information regarding the Conference, see the staff at the Delegate Help Desk located in the Registration area of the ICC. SUPPORTED BY Monday, May 2 Networking Break 10:30 – 11:15 Lunch LUNCH SUPPORTED BY 12:45 – 14:15 Networking Break 15:45 – 16:30 Exhibition The Exhibition is located in Hall 3 at the International Convention Centre (ICC). Please find a floor plan of the exhibition and a detailed list of all exhibitors on page 54. Tuesday, May 3 Networking Break 10:30 – 11:15 Exhibition Opening Hours Lunch 12:45 – 14:15 Sunday, May 1 18:30 – 21:30 (Opening Networking Reception) Networking Break 15:45 – 16:30 Monday, May 2 10:30 – 19:30 Tuesday, May 3 10:30 – 19:30 Wednesday, May 4 10:30 – 12:00 Wednesday, May 4 Networking Break 10:30 – 11:15 Onsite Mobile Application Lost and Found Lost and Found items should be returned/ claimed at the Registration and Foyer Area at the ICC. Networking Breaks & Lunches – Hall 3 (Exhibition & Posters) During the Conference, refreshments and snacks will be provided for registered delegates in Hall 3. iMig2016.ORG Plan your personalized iMig 2016 Conference schedule. Browse sessions by track, date, and time. The mobile application includes all abstracts submitted and accepted for the iMig 2016 Conference. Sync with your Outlook calendar and many more. Get local information and the weather forecast for the next 5 days. Available for iPhone, iPad, Android. Download the app from www.iMig2016.org. SUPPORTED BY 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 39 Parking The nearest car parks to the ICC are located at the Barclaycard Arena. Current charges are from £2.30 for up to 2 hours to £8.00 for 24 hours. Payment can be made by coin or card at the Pay and Display machines. Alternative parking is located at Brindleyplace or Paradise Circus. Poster Session 3 Wednesday, Monday 4, 2016 Poster Display Hours: Meet the Author: 10:30 – 12:00 10:30 – 11:15 Press & Media Room Poster Sessions The Poster Sessions will be held in the Exhibit Area. For detailed information on Posters displayed please refer to the Programme pages. Poster Session 1 Monday, Monday 2, 2016 Poster Display Hours: 10:30 – 19:30 Meet the Author: 10:30 – 11:15 12:45 – 14:15 15:45 – 16:30 Mixer and Discussion: 18:00 – 19:30 Poster Session 2 Tuesday, Monday 3, 2016 SUPPORTED BY Poster Display Hours: 10:30 – 19:30 Meet the Author: 10:30 – 11:15 12:45 – 14:15 15:45 – 16:30 Mixer and Discussion: 18:00 – 19:30 iMig2016.ORG The Media Suite on Level 4 at the ICC is the designated Press & Media Room. Press and Media passes are issued to individuals representing a recognized news organization, including freelancers who contribute to such organizations. Individuals involved with public relations, marketing sales, circulation, advertising, or any other non-editorial function are NOT eligible for press passes. Press and Media representatives are required to check in at the Registration Counter. Media Press credential is required to receive a Press/ Media Badge. Press & Media Room Opening Hours Monday, May 2 07:30 – 17:00 Tuesday, May 3 07:30 – 17:00 Wednesday, May 4 07:30 – 11:00 Internet access and a printer are available in the Media Room to assist credentialed media representatives. Public Transportation By Public Transit Network West Midlands provides city transit for tourists and residents seven days a week via Bus, Train and Metro. 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 41 By Car Birmingham’s city centre is partially pedestrianised and has several unintuitive one-way systems. Expect to pay £1 – £1.50 per hour in Pay & Display areas and more on street meters. Parking attendants patrol popular areas regularly, so expect a fine if you return late or a clamp if you’re parked illegally. By Taxi Birmingham has an abundance of taxi ranks all over the city, the best-served being New Street Station. Both hackney carriages and private hire vehicles are easy to find, but you should exercise caution and not get into an unmarked car or one you haven’t booked. By Train Birmingham has a single metro line, running between Snow Hill Station and Wolverhampton, via the Jewellery Quarter, West Bromwich, Wednesbury and Bilston. The Metro runs from roughly 06:30 – 23:30 Monday to Saturday, and 08:00 – 23:00 Sunday and bank holidays. Fares vary with distance, but expect to pay around £2 for a single, £3.50 for a return and £4.50 for a day pass. By Foot Birmingham’s City Centre is partially pedestrianised, and most things to see and do can be reached on foot. Registration Counter Hours iMig 2016 Registration is located on the Registration and Foyer Area at the ICC. Sunday, May 1 16:00 – 21:00 Monday, May 2 07:30 – 17:00 Tuesday, May 3 07:30 – 17:00 Wednesday, May 4 07:30 – 11:00 Smoking Smoking is prohibited in all areas of the Hyatt Regency Birmingham and the ICC. Speaker Ready Room The Media Suite at the ICC is the designated Speaker Ready Room. All presenters are required to submit and/or preview their slides at least 3 hours prior to their scheduled presentation to ensure compatibility with the Conference AV Equipment. Staff and Volunteers Volunteers are happy to assist with any questions delegates may have regarding the Conference or the International Convention Centre. Delegates can easily locate them by their staff/volunteer shirts. SUPPORTED BY Wireless Internet Wireless Internet is available throughout the ICC. GENEROUSLY SUPPORTED BY DISCLAIMER The organizers have made every attempt to ensure that all information in this publication is correct. The organizers take no responsibility for changes of the Programme or any loss that may occur as a result of changes of the Programme. Some of the information provided in this publication has been provided by external sources. Although every effort has been made to ensure the accuracy, currency and reliability of the content, the organizers accept no responsibility in that regard. 42 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG AWARDS 44 IMIG WAGNER MEDAL IMIG RESEARCH AWARD The iMig Wagner Medal will be awarded during the Gala Dinner. The iMig Research Award will be awarded during the Gala Dinner. J. Christopher Wagner was a leader in the field of Mesothelioma who made major contributions to the understanding of Mesothelioma, its cause and the goals for prevention. By his clinical observations and animal studies, he was the first to establish that Mesothelioma was caused by asbestos. Inspired by this example, the International Mesothelioma Interest Group presents the Wagner Medal every two years to an individual who has made major original contributions to the understanding of Mesothelioma, either in basic or applied research. It is the highest honour presented by the International Mesothelioma Interest Group to a leader in the field. The iMig Research Awards will be awarded every two years to recognize the potential significance and impact on the field of novel mesothelioma research (basic, translational, or clinical) that has been published or presented since the prior International Conference of the International Mesothelioma Interest Group. Research to be presented during the current Conference would qualify an investigator for the iMig Research Awards. 2002 Marie-Claude Jaurand PhD, France 2004 Bruce Robinson, MD, Australia The iMig Service Award may be awarded every two years to an individual who has made significant and sustained contributions of service to the mission of the International Mesothelioma Interest Group. 2006 Harvey Pass, MD, USA 2008 Brooke Mossman, PhD, USA 2010 Steven Albelda, MD, USA 2012 Joseph R. Testa, PhD. USA 2014 Raffit Hassan, MD, USA IMIG SERVICE AWARD The iMig Service Award will be awarded during the Gala Dinner. 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG BEST INVESTIGATOR AWARDS The Best Investigator Award Recipient will receive their award during the Presidential Closing. Edmund Moon, USA MS16.01:Blockade of Protein Kinase A (PKA) Localization Augments Trafficking And Anti-Tumor Efficacy Of CAR T Cells YOUNG INVESTIGATOR AWARDS SUPPORTED BY Young Investigator Award Recipients will receive their awards during the Presidential Closing. Hannah Moody, United Kingdom Floris Dammeijer, Netherlands MS11.05: MicroRNA-31 Regulates Chemosensitivity in Malignant Pleural Mesothelioma via Altered Intracellular Drug Localisation MS16.03: CSF1R-Blockade Synergizes with Dendritic Cell Immunotherapy in a Mesothelioma Preclinical Model Rossella Bruno, Italy Kevin Lamote, Belgium MS08.04: Digital Gene Expression Profiling to Separate Malignant Pleural Mesothelioma from Benign Reactive Mesothelial Hyperplasia MS05.02: Haptoglobin Phenotype Is a Risk Factor for Malignant Pleural Mesothelioma Marissa Williams, Australia MS04.03: Tumour Suppressor microRNAs Regulate PD-L1 Expression in Malignant Pleural Mesothelioma DEVELOPING NATIONS TRAVEL GRANTS SUPPORTED BY Developing Nations Travel Grant Recipients will receive their awards during the Presidential Closing. Ahmed El Bastawisy, Egypt PP01.61: Malignant Pleural Mesothelioma in Young People iMig2016.ORG Hala Aziz Shokralla, Egypt PP01.29: Does Malignant Pleural Mesothelioma with Metastases at First Presentation Really Benefit from Chemotherapy? 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 45 SPECIAL WORKSHOP SPECIAL WORKSHOP Sunday, May 1 12:30 – 18:00 14:45 SS01.06: The Difference between the Psychological Care Needs for Those with Lung Cancer and Mesothelioma A Review of the Literature Hannah Ball, Oxford University Hospitals NHS Foundation Trust, United Kingdom 15:15 SS01.07: Afternoon Tea 16:00 SS01.08: Top Tips for Symptom Management in Mesothelioma Karen Lord, University Hospitals of Leicester, United Kingdom 16:30 SS01.09: A Global Overview of Clinical Trials in Mesothelioma (Pleural and Peritoneal) Mary Hesdorffer, Mesothelioma Applied Research Foundation, USA 17:00 SS01.10: Taking Mesothelioma ‘On the Road’ Judy Rafferty, Lung Foundation Australia, Australia 17:30 SS01.11: Key Messages and Campaigns Melinda Kotzian, Mesothelioma Applied Research Foundation, USA & Laurie Kazan-Allen, British Asbestos Newsletter, United Kingdom Mesothelioma Nurse Meeting Location: The Sonata Room, Hyatt Regency Birmingham 12:30 SS01.01: Networking Opportunity 13:00 SS01.02: Welcome Liz Darlison, Mesothelioma UK, United Kingdom & Vanessa Beattie, Aintree University Hospital, United Kingdom 13:15 SS01.03: Nursing Care for Mesothelioma Patients Receiving Immunotherapy Michelle Turner, Maryland Proton Therapy Center, USA 13:45 SS01.04: What is in a ‘Living with Meso’ Toolkit Natalie Doyle, Royal Marsden, United Kingdom 14:15 SS01.05: A Coordinated Approach to Setting up and Managing a Comprehensive Mesothelioma Service Melissa Culligan, University of Maryland, USA THIS WORKSHOP IS SUPPORTED BY 46 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG Together, We’ll Find a Cure At Kazan Law, we fight for justice and financial compensation for mesothelioma victims and their families. But our commitment doesn’t end there: We also seek to better understand this fatal illness and, ultimately, help you find a cure. That’s why the Kazan McClain Partners’ Foundation has steadfastly invested in supporting the research behind many of today’s mesothelioma medical insights and breakthroughs. To the right are some of our Foundation’s most recent endeavors. Over $6,000,000 for Research The Kazan McClain Partners’ Foundation helps support mesothelioma research at leading medical facilities and has supported iMig since 2006 at meetings all over the world. We partner with esteemed learning institutions to find a cure for asbestos diseases. A Few of the Research Studies Supported by Kazan Law • Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas (Hio Chung Kang, et al, University of California San Francisco) Oncotarget, Advanced Publications 2016 • miR-1 Induces Growth Arrest and Apoptosis in Malignant Mesothelioma (Yue Xu, et al, Stanford University) Chest 2013 • Radiologic–pathologic correlation of mesothelioma tumor volume (Samuel G. Armato III, et al, University of Chicago) Lung Cancer, Elsevier 2014 $100,000 to Honor iMig Attendees At iMig 2014 in Cape Town we offered $100,000 in micro grants to support research conducted by iMig attendees. This year in Birmingham, we again invite iMig attendees to apply for grants from $1,000 up to $25,000.* iMig Young Investigator Awards Since 2006, Kazan Law has been a proud and major financial supporter of iMig. We proposed the Young Investigator Awards program, which we helped to fund in 2008 and have funded it ever since, and have committed to continue funding in the years ahead. *Please send a brief email to [email protected] explaining how much money you need, what you will spend it on, and what publishable goals you hope to accomplish. For more information, visit www.kazanlaw.com/iMig-2016 to learn more about what we do. INDUSTRY-SUPPORTED SYMPOSIA Tuesday, May 3 Mesothelioma: Moving Forward 08:00 – 08:45 “Surgical Innovations in Thoracic Surgery” Hedy Kindler, University of Chicago Medical Center, USA 13:50 ISS02.03: The Promise of ImmunoOncology in the Treatment of Malignant Mesothelioma Michele Maio, Istituto Toscano Tumori, Italy Hall 9 Chair: Raja Flores, Mount Sinai Health System, USA 08:00 ISS01.01: The Use of Permacol™ Surgical Implant in EPD Surgery David Waller, Glenfield Hospital, United Kingdom 08:15 ISS01.02: The Use of Biological Mesh in Chest Wall Reconstruction Marco Scarci, Papworth Hospital NHS Foundation Trust, United Kingdom 08:30 ISS01.03: The Use of Buttressing in Emphysematic Lung States Walter Weder, University Hospital Zürich, Switzerland SUPPORTED BY Wednesday, May 4 08:00 – 08:45 “Future Directions: Enhancing Therapies through Immuno-Oncology Combinations” Hall 6 Moderator: Daniel H. Sterman, NYU Langone Medical Center, USA SUPPORTED BY 8:00 ISS03.01: Introductions 8:05 ISS03.02: Rational Combinations in Immuno-Oncology (IO) Evan W. Alley, Penn Presbyterian Medical Center, USA 8:25 ISS03.03: Immunotherapy Combinations in Mesothelioma Chair: Michele Maio, Istituto Toscano Tumori, Italy Dean Fennell, University of Leicester & Leicester University Hospitals 13:20 ISS02.01: The Role of Surgery in the Treatment of Malignant Mesothelioma RSVP at https://imig2016symposium-immunooncology-combinations.eventbrite.com Raphael Bueno, Brigham and Women’s Hospital, USA 13:35 ISS02.02: Systemic Therapy for Tuesday, May 3 13:15 – 14:15 “State of the Art Treatment of Malignant Mesothelioma” Hall 9 iMig2016.ORG SUPPORTED BY 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 49 EXHIBITION INFORMATION Exhibition Location and Hours Exhibition Highlights The iMig 2016 Exhibition is located in Hall 3 of the ICC. Welcome Networking Reception Sunday, May 1 Exhibition Opening Hours Sunday, May 1 18:30 – 21:30 (Opening Networking Reception) Monday, May 2 10:30 – 19:30 Tuesday, May 3 10:30 – 19:30 Wednesday, May 4 10:30 – 12:00 18:30 – 21:30 Included with full Conference Registration, not included in Single-Day Registration Additional tickets for family and friends can be purchased for £40 at Registration The iMig 2016 Exhibition will open with the Welcome Networking Reception, allowing you the opportunity to mix and mingle with exhibitors, colleagues and friends. SUPPORTED BY d w ed V .u ic is ni at it te ed o le w ur ga e ls bs er it vi e: ce s. or g w w Free, expert legal support from Unite Legal Services Unite members and their families get free legal support for mesothelioma claims, and will always keep 100% compensation. Contact Unite Legal Services first and get: Free representation for any asbestos-related disease claim, including mesothelioma Expert legal advice from highly experienced asbestos disease solicitors 100% compensation within the union scheme “ Unite Legal Servic was fantastic. sat down with me and went through my emplment history. I worked out actly en I had been in contact with asbtos and th pursued a compensation claim on my behalf. Charlie, Unite member For expert mesothelioma legal support call Unite Legal Services on: 0800 709 007 www.unitelegalservices.org @UniteLegal ” EXHIBITOR LISTING ALPHABETICAL Company Asbestos Disease Awareness Organization Asbestos Victims Support Groups Forum Bayer HealthCare Pharmaceuticals, Inc. Boyes Turner LLP British Thoracic Oncology Group (BTOG) CareFusion Fieldfisher - Mesothelioma Claims Specialists Fujirebio Hope Foundation for Cancer Research Hugh James IBAS, International Ban Asbestos Secretariat International Thoracic Oncology Nursing Forum Irwin Mitchell June Hancock Mesothelioma Research Fund Leigh Day Lawyers Lilly Oncology Macmillan Cancer Support Medtronic Mesothelioma UK Charitable Trust MesobanK Mesothelioma Applied Research Foundation MSD Oncology Novum Law Rocket Medical Slater & Gordon Tissuemed Ltd. 54 NUMERICAL Booth # TT6 TT8 15 9 TT2 10 16 5 TT9 13 14 TT3 18 TT5 8 1 TT7 11 TT1 4 TT4 12 19 7 17 6 Booth # 1 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 TT1 TT2 TT3 TT4 TT5 TT6 TT7 TT8 TT9 Company Lilly Oncology MesobanK Fujirebio Tissuemed Ltd. Rocket Medical Leigh Day Lawyers Boyes Turner LLP CareFusion Medtronic MSD Oncology Hugh James IBAS, International Ban Asbestos Secretariat Bayer HealthCare Pharmaceuticals, Inc. Fieldfisher - Mesothelioma Claims Specialists Slater & Gordon Irwin Mitchell Novum Law Mesothelioma UK Charitable Trust British Thoracic Oncology Group (BTOG) International Thoracic Oncology Nursing Forum Mesothelioma Applied Research Foundation June Hancock Mesothelioma Research Fund Asbestos Disease Awareness Organization Macmillan Cancer Support Asbestos Victims Support Groups Forum Hope Foundation for Cancer Research 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG EXHIBITION FLOOR PLAN iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 55 EXHIBITOR BIOGRAPHIES Asbestos Disease Awareness Organization Table # TT6 Asbestos Disease Awareness Organization (ADAO), an independent nonprofit, was founded by the Reinstein and Larkin families in 2004. ADAO remains dedicated to raising public awareness about the dangers of asbestos exposure, advocating for an asbestos ban, and protecting asbestos victims’ civil rights through our education, advocacy, and community initiatives. (www.adao.us) Asbestos Victims Support Groups Forum Table # TT8 The Asbestos Victims Support Groups Forum UK is the umbrella organisation for asbestos victims support groups in the UK. We work collectively to provide one voice for asbestos victims nationwide. We provide advice and support for people diagnosed with asbestos diseases and their families and campaign for justice for all asbestos victims. (www.asbestosforum.org.uk) Bayer HealthCare Pharmaceuticals, Inc. Booth # 15 Bayer is committed to delivering SCIENCE FOR A BETTER LIFE by advancing a portfolio of innovative treatments. Bayer’s oncology franchise now includes three oncology products and several other compounds in various stages of clinical development. (www.bayer.com) Boyes Turner Booth # 9 Boyes Turner’s asbestos team, dedicated to campaigning for the rights of asbestos victims, working to secure justice for those diagnosed with asbestos conditions and committed to assisting asbestos disease sufferers with the consequences of their illness, is delighted and proud to support iMig 2016. (www.boyesturner.com) British Thoracic Oncology Group (BTOG) Table # TT2 The British Thoracic Oncology Group (BTOG) is the multi-disciplinary group for professionals involved with thoracic malignancies. BTOG aims to improve the care of patients with thoracic malignancies through multidisciplinary education, developing and advising on guidelines for patient care and facilitating and nurturing clinical trial ideas into full protocols. (www.btog.org) CareFusion Booth # 10 The PleurX® catheter system is the easy-to-use and effective choice for managing recurrent malignant pleural effusions and malignant ascites. PleurX® has been used to treat more than 300,000 patients since 1997 and could help your patients take control by enabling them to manage symptoms associated with fluid build-up at home. (www.carefusion.com) 56 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG Fieldfisher - Mesothelioma Claims Specialists Booth # 16 Fieldfisher is one of the UK’s foremost mesothelioma claims practice. We are renowned for our success and commitment in asbestos and mesothelioma claims. We visit clients at home and act on a ‘no win, no fee’ basis. Legal 500, describe us as being ‘in a league of their own nationally’ and ‘head and shoulders above the rest in terms of skills, experience and quality’. (www. fieldfisher.com) Fujirebio Booth # 5 Fujirebio is a leading international healthcare company and world-wide leader in Oncology who develops and markets high quality and robust IVD solutions. Utilising the Lumipulse G series automated CLEIA analysers, the product portfolio includes both routine and unique immunoassays, including Soluble Mesothelin Related Peptide (SMRP) and KL-6. (www.fujirebio-europe.com) Hope Foundation for Cancer Research Table # TT9 Hope Against Cancer is Leicestershire and Rutland’s local cancer research charity. We were established in 2003 to bring cutting-edge research to our area and make clinical trials available to local people. Since 2003 we have raised almost £4m and funded 40 research projects tackling many different forms of cancer. (www.hfcr.org) Hugh James Booth # 13 Hugh James’s industrial disease team represents individuals and their families who are suffering from respiratory illnesses acquired through employment. The firm’s expert solicitors make the claims process simple and straightforward and offer free, no obligation, initial advice as well as arranging home visits across England and Wales. (www.hughjames.com) IASLC Booth # TT10 The International Association for the Study of Lung Cancer (IASLC) is the only global organization dedicated to the study of lung cancer. Founded in 1974, the association’s membership includes more than 5,000 lung cancer specialists in over 100 countries. IASLC members work to enhance the understanding of lung cancer among scientists, members of the medical community and the public. (www.iaslc.org) IBAS, International Ban Asbestos Secretariat Booth # 14 The International Ban Asbestos Secretariat (IBAS), established in 2000, provides a conduit for the exchange of information between groups and individuals working to achieve a global asbestos ban and alleviate the damage caused by widespread asbestos use. IBAS channels the views of a network of victims’ groups, medical and legal professionals and concerned individuals to raise awareness of asbestos hazards and provide informed comment on current developments. (www.ibasecretariat.org) iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 57 International Thoracic Oncology Nursing Forum Table # TT3 The ITONF is an organisation for Nurses who are directly caring for people with lung cancer or mesothelioma and who have a common focus of improving patient care, health care delivery and outcomes for patients. This network provides an opportunity for debate, education and knowledge transfer. Membership is free. (www.itonf.com) Irwin Mitchell Booth # 18 Irwin Mitchell LLP has over 30 years’ experience in successfully recovering compensation for clients whose lives are affected by mesothelioma and other asbestos-related illnesses. Our specialist solicitors, based in 11 Regional Offices, have helped and supported several thousand clients after exposure to asbestos through their work, domestic or environmental circumstances. (www.irwinmitchell.com) June Hancock Mesothelioma Research Fund Table # TT5 The June Hancock Mesothelioma Research Fund (JHMRF) is an independent UK-based charity dedicated to funding high quality research and providing information and support to patients and their families. The charity was founded in 1997 and has raised over £1.5m. JHMRF has funded several major research projects, PhD and travel fellowships. (www.junehancockfund.org) Leigh Day Lawyers Booth # 8 Leigh Day is a law firm with a formidable reputation in asbestos litigation as a consequence of representing victims for over 25 years in the UK and abroad. Our cases set precedents. We have good relationships with medical practitioners. We give lectures on asbestos disease. One of our lawyers has raised over £60,000 to help fund research into a cure for mesothelioma. (www.asbestos.leighday.co.uk) Lilly Oncology Booth # 1 For more than fifty years, Lilly has been dedicated to delivering life-changing medicines and support to people living with cancer and those who care for them. Lilly is determined to build on this heritage and continue making life better for all those affected by cancer around the world. (www.lilly.co.uk) Macmillan Cancer Support Table # TT7 The Health and Social Care team from Macmillan Cancer Support covers a wide range of services. They influence policy and opinion leaders, support service improvement and work with partner organisations to implement new service models. The team has four Programmes supporting the cancer care pathway; prevention and diagnosis; treatment and recovery; workforce (including carers); and end of life care. (www.macmillan.org.uk) 58 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP iMig2016.ORG Medtronic Booth # 11 As a global leader in medical technology, services and solutions, Medtronic improves the lives and health of millions of people each year. We use our deep clinical, therapeutic, and economic expertise to address the complex challenges faced by healthcare systems today. Let’s take healthcare Further, Together. (Medtronic.com) Mesothelioma UK Charitable Trust Table # TT1 Mesothelioma UK Charitable Trust is a national charity, hosted by University Hospitals of Leicester. The charity provides support to all those affected by mesothelioma, providing impartial, up-to-date information and advice, access to specialist advice through the free phone helpline, the website and printed patient information. (www.mesothelioma.uk.com) MesobanK Booth # 4 MesobanK is the UK’s largest unique collection of high-quality tissue, cell, blood samples and data from mesothelioma patients. Novel cell lines and a TMA of >800 patients also available. MesobanK is dedicated to the study of mesothelioma by providing samples for research. (www.mesobank.com) Mesothelioma Applied Research Foundation Table # TT4 The Mesothelioma Applied Research Foundation is the only 501(c)(3) nonprofit organization dedicated to eradicating mesothelioma and the suffering caused by this cancer. The organization: • Funds mesothelioma research and has awarded over $9.3 million to date; • Provides patient support services and education; • Advocates Congress for increased federal funding for mesothelioma research. (www.curemeso.org) MSD Oncology Booth # 12 Our goal is to translate breakthrough science into innovative oncology medicines to help people with cancer worldwide. At MSD Oncology, helping people fight cancer is our passion and supporting accessibility to our cancer medicines is our commitment. Our focus is on pursuing research in immuno-oncology and we are accelerating every step in the journey – from lab to clinic – to potentially bring new hope to people with cancer. (www.msd-uk.com) Novum Law Booth # 19 At Novum Law, we are experts in dealing with mesothelioma and asbestos-related diseases. Our specialist asbestos team have substantial experience in dealing with these highly complex cases and have recovered millions of pounds of compensation for hundreds of clients. We cannot change the diagnosis but we can help to get financial compensation that can bring some peace of mind for the future. (www.novumlaw.com) iMig2016.ORG 13TH INTERNATIONAL CONFERENCE OF THE I NTERNATIONAL MESOTHELIOMA INTEREST GROUP 59 Rocket Medical Booth # 7 Rocket Medical UK manufacturers of Indwelling Pleural and Peritoneal Catheters and their associated consumables. We have over 8 years experience of caring for patients with Pleural Effusions and abdominal ascites associated with Mesothelioma. We will have all the products for you to handle on our stand and will be available to demonstrate the products and answer any queries. (www.rocketmedical.com) Slater & Gordon Booth # 17 Slater and Gordon have many years’ experience representing people exposed to asbestos who develop mesothelioma. With offices throughout Australia and the UK, our specialist lawyers have been involved in some of the most important and ground-breaking asbestos cases. (www.slatergordon.co.uk) Tissuemed Ltd. Booth # 6 Tissuemed is a UK company that develops, manufactures and supplies TissuePatch™, a synthetic, self-adhesive, absorbable surgical reinforcement and sealant film. TissuePatch™ requires zero preparation, is easy to apply, and is a functionally and economically effective method of managing persistent air leaks in both open and VATS procedures. (www.tissuemed.com) Understanding that mesothelioma also affects those closest to you. With a dedicated team of solicitors we make every effort to tailor the support and advice you and your family need, because we know the impact of your condition is unique and affects each person differently. Irwin Mitchell, standing by you. 0370 1500 100 www.irwinmitchell.com @irwinmitchell For a list of our offices visit our website . Irwin Mitchell LLP is a limited liability partnership registered in England & Wales, with number OC343897, and is authorised and regulated by the Solicitors Regulation Authority. All Scottish cases will be handled a separate Scottish legal practice, Irwin Mitchell Scotland LLP, which is regulated Law Society of Scotland. 13TH INTERNATIONAL CONFERENCE OFbyTHE I NTERNATIONAL MESOTHELIOMA INTEREST GROUPby theiMig2016.ORG 60 Like You, We Provide Personalized Care As a clinician or research scientist, you look beyond the science to provide compassionate and personalized care for mesothelioma patients. At Kazan Law, we too provide a full range of services for those suffering from mesothelioma. For 42 years we have provided patients with access to resources and information and a voice in court, along with a commitment to supporting the research that will, someday, lead us to a cure. Our patient pathway offers multiple levels of care, including: • Research funding— The Kazan McClain Partners’ Foundation has proudly contributed more than $6 million to mesothelioma awareness and research, and will continue to do so until there is a cure. • Ban Asbestos— The firm and its Foundation has been a major financial supporter of the International Ban Asbestos movement for over 20 years. • Top verdicts and settlements— Won on behalf of mesothelioma patients exposed to asbestos by unfeeling corporations. While money cannot replace a patient’s life, it can prevent additional, undue suffering of family members by paying the bills. • Mesothelioma Circle—A website devoted to mesothelioma patients and their loved ones, filled with resources and information on medical treatments, clinical trials, legal rights, and more. Let’s work together to ensure that mesothelioma patients get the personalized health care and financial support they need during an emotional and painful time in their lives. Visit www.kazanlaw.com/iMig-2016 to learn more about our services.