Newsletter - Society for the Study of Reproduction
Transcription
Newsletter - Society for the Study of Reproduction
JAN 24 1990 Society for the Study of Reproduction Newsletter January 1990 Vol. 7, Number 1 Notes from the President The committees for the current year are exceptionally active and strong as evidenced by the several excellent contributions to this newsletter. This is the stuff of which successful organizations are made! To volunteerfor next year's committees, contact President-elect Dr, Anita Payne at the Department of Ob/Gyn, 21221 Woman's Hospital, University of Michigan, Ann Arbor, MI48109-G278. Plans for the 1990 meeting in Knoxville are well underway under the capable leadership of Local Arrangements Chairman, Dr. Tom Chen, and Program Chairman, Dr. David Garbers. The Symposium and State-of-the-Art Presentations are highlighted elsewhere in this newsletter. In the Spring Newsletter, I want to add my thoughts to those which have previously been so well-stated in this space vis a vis some major, difficult problems which have faced us for a long time: What can we do about the funding crisis? How can we achieve more contributions to our annual meeting and to our journal in those areas considered to be exciting, rapidly moving frontiers of contemporary reproductive biology? In the meantime, if you have thoughts about these issues, I would be grateful if you would communicate them to me. David W. Schomberg Notes from Knoxville, TNSite of the 1990 Annual Meeting V Members of the Local Arrangements Committee and the UniverSity ofTennessee, Knoxville would like to extend a warm invitation to all SSR members to join us for the 23rd annual meeting. Knoxville is known for being the gateway to the Great Smokies and the host of the World's Fair eight years ago. Less known to people outside of the region is that the city has consistently ranked high among America'S ~most livable cities· because of its attractive location, friendly environment, and rich cultural heritages. Knoxville was founded by James White who built the James White Fort in 1786 and named in honor of General Henry Knox, Secretary of War in President Washington's cabinet. Here the first frame house west of the Alleghenies was built in 1792 for William Blount, Governor of the Territory of the United States south of the River Ohio, and his family. Today both structures still stand and are among Knoxville's most famous landmarks. Knoxville sits in a valley surrounded by the Great Smokies to the south, the Cumberland Plateau to the .Llorth and west and the Blue Ridge Mountains to the northeast. The Great Smoky Mountains National Park, with its half a million acres of protected wilderness land, is the most visited park in our nation. If you enjoy water sports, you will find lakes for boating, fishing, etc. within a half-hour drive in all four directions. You Ovarian WorkshopJuly 12-14, 1990 The eighth biennial Ovarian Workshop sponsored by Serono Symposia will be held on July 12-14, 1990 In Maryville, TN. We are compiling a list of people who would be Interested In receiving announcements regarding the workshop. If you wish to be Included on this list please send your name and permanent address to: Dr. Geula Glbort Department of Physiology and Biophysics University of Illinois 835 South Wolcott Avenue (m/c 901) Chicago, IL 60612 Telephone: 312/996-6077 Forge with dozens of amusement parks including Dollywood, outlet malls, crafts and variety shops is just a half-hour drive toward the Smokies. Gatlinburg, a small, attractive foothill resort, gives you a taste of the '-../ Alpine and breathtaking views on top of Ober Gatlinburg. A note of warning, if you plan a trip to the Smoky Mountains area on your way to the SSR meeting, try not to come on the Fourth of July weekend because you will find yourself caught in a traffic jam that backs up for miles in the Pigeon Forge-Gatlinburg area . You can, of course, stay in town. Knoxville with its nearby neighbors-Oak Ridge and Maryville/ Alcoa-are a metropOlitan area with a population of about half a million. With its newly renovated downtown area, you will have plenty of selections for fine dining, exciting entertainment, and festivities in the evening. In fact, the National Quiltter's Association (anticipated attendance: 3,000) will have their national meeting and exhibits on the World's Fair site at the same time of our meeting. Therefore, if you plan to stay in downtown hotels, we urge you to make reseNations early. If you are not down-regulated by all the Signal transductions occurring at the meeting and crave for more science and technology, you may want to explore Oak Ridge, the "city behind the fence" and one of America's best-kept secrets during World War II. Oak Ridge is best known for its part in the Manhattan project and is home of the Oak Ridge National Lab and one of the largest energy exhibits In the world. Maryville, the center stage of the recent frozen-embryo trail, provides another incentive for SSR and the Ovarian Workshop to meet here. Knoxville is within a day's drive of half the US population, if you decide to drive, we suggest that you plan ahead or stop by a Welcome Center to pick up a brochure on "The Tennessee Scenic Parkway System" and leisurely follow the Mockingbird signs. You will be delighted to find Tennessee's varied and beautiful landscape and historical sites. Finally, the local members promise to provide you with a hospitable stay and hope that "y' all come. " Third Annual Techniques in Reproductive Biology Workshop Knoxville TN-July 15, 1989 Topic: Methods for Separating and Culturing Cells In Vitro • Cell separation and isolation techniques applied to the mammalian testes" Clarke F. Millette, Ph.D. Department of Anatomy University of South Carolina Columbia, SC • Use of extracellular matrices In epithelial cell cultures" Charfes StreulI, Ph.D. Laboratory of Cell Biology Lawrence Berkeley Laboratory Berkeley, CA 'Sterolds and growth factors In cell and organ culture" John Mclachlan, Ph.D. NIH/NIEHS Research Triangle Park, NC For more Information please contact: Asgi T. FazJeabas Chair, SSR Education Committee Department of Obstetrfcs and Gynecology Unlverfsty of Illinois 840 South Wood Street (m/c 808) Chicago, IL 60612 Telephone 312/996-0994 Financial assistance for this workshop Is provided by Serno Symposia, U.S.A. Meeting Site for the 1992 SSR Meeting may also want to drive 40 minutes down to the Ocoee for an afternoon of white-water rafting. If you prefer a quiet afternoon away from the traffic and heat, go to the Lost Sea, the largest underground lake with attractive cave flowers and rock formations, or wander through natural trails under tall woods in the scenic Norris Dam State Park where the first TVA dam was built. For family activities, we recommend the Museum of Appalachia in Norris where some forty log structures containing pioneers' artifacts are carefully preseNed and displayed. For joy rides and fun, Pigeon The University of British Columbia has been selected by the Board of Directors for the 1991 SSR Meeting. We are accepting bids for the 1992 meeting.lfyou are interested in hosting the 1992 SSR Meeting, please contact Mary Hunzicker-Dunn, Future Meetings Chairperson, Northwestern University Medical School, Department of Molecular Biology, 303 East Chicago Avenue, Chicago, IL 60611. You will be sent a questionnaire which identifies facility require- 2 "--'" ments, costs, etc. Location choice is based, in part, on regional location with respect to previous meetings, meeting facilities, costs, and access by air. 1990 SSR Meeting Knoxville, TN-July 16-18, 1990 Symposium: Mechanisms of Cellular Signal TransducHon Changes in the Bylaws -Multlple Roles of G Portlens In Transmembrane Signal Transductlon The 1988-89 Bylaws Committee of the Society for the Study of Reproduction made several recommendations to the Board of Directors which were acted upon by the Directors at their summer meeting. The following are the changes approved by the Board of Directors and which have been or will be voted upon by the membership. Lutz Blrnbaumer, Ph.D. Department of Cell Biology Baylor College of Medicine Houston, TX -Catecholamine Receptors: Structure, Functlon, and Regulatlon· Article XIX. Distribution on Dissolution. Marc G. Caron, Ph.D. Departments of Cell Biology and Medicine Duke University Medical Center Durham,NC Previous wording: Upon dissolution of the society, the Board of Directors shall distribute the assets and accrued income to one or more organizations which shall meet the limitations prescribed in Sections 1 to 6 inclusive of Article XVIII. -The Molecular Basis of Signalling In the Spermatozoon· Present wording: Upon dissolution of the Society, the Board of Directors shall, after paying or making provisions for the payment of liabilities of the SOCiety, dispose of all assets of the Society, to one or more organizations, organized and operating exclusively for charitable, educational, religious or scientific purposes, and shall at the time quality as an exempt organization or organizations under Section SOl(c) (3) of the I.R.S. of 1954 (or corresponding provisions of any future U.S. Internal Revenue Code), and which shall meet the limitations prescribed in Sections 1 to 6 inclusive of Article XVIII. David L. Garbers, Ph.D. Department of Physiology Vanderbilt Medical Center Nashville, TN (a) Regular Member: Any individual who has demonstrated professional competence in and made scientific contributions to the field of reproductive biology shall be eligible for Regular membership in the Society. (b) Member Emeritus: Regular Members who reach normal retirement age or who retire early for medical reasons shall be eligible to petition the Executive Secretary to have the Board of Directors approve a waiver of their annual dues. Such Members shall otherwise by synonymous with Regular Members. (c) Associate Member: Any individual or institution with a scientific interest in the field of reproductive biology shall be eligible for Associate Membership. (d) Trainee Member: Any individual in predoctoral or postdoctoral training in the field of reproductive biology and who has been recommended by a Regular member shall be eligible for Trainee Membership. (e) Sustaining Associates: Any philanthropic individual. organization, corporation, or foundation which contributes substantially to the support of the SOCiety may, by action of the Board of Directors, be admitted to membership as a Sustaining Associate. Regular Members, Members Emeritus, As- Rationale: This important proposal allows our Society to acquire a tax exempt status with the Internal Revenue. Previously, the SOCiety was a "notfor profir organization. This meant that, when a contribution was made to the Society, the donor could not legally claim the contribution as a tax deduction with the I.R.S. The changes in wording in Article XIX were approved unanimously by the membership at the meeting of the SSR in August, 1989 in Columbia, Missouri and, thus, are now part of the Bylaws of the SSR. Two other changes in the Bylaws were approved by the Board of Directors. These changes are: V Article V Membership, Section 1. Categories of Membership Present wording: The categories of membership in the Society shall be: 3 philanthropic individual. organization, corporation, or foundation which contributes substantially to the support of the Society may, by action of the Board of Directors, be admitted to membership as a Sustaining '-../ Associate. Regular Members, Members Emeritus, Honorary Members, Associate Members, Trainee Members and Sustaining Associates shall hereinafter be referred to as "Members: exc~pt where specifically identified. State-of-the-Art Lectures -Molecular Mechanisms Underlying Hormonal Regulation and Tissue-Specific Expression of the Gonadotropin Genes" John H. Nilson, Ph.D. Department of Pharmacology Case Western Reserve University Cleveland, OH Elizabeth Robertson, Ph.D. Department of Genetics and Development Columbia University NewYork,NY Rationale: In the past there have been Hartman awardees who have not been members of the SSR. It is believed that the most important cFiteria for selection of a Hartman awardee is his/her overall impact in science, and should not be restricted to current membership of the Society. However, if the Society so honors an individual. that individual should be made an honorary member of the SSR. - How the Egg Regulates Sperm Function During Gamete Interaction" Article XI Committees, Section 2. Appointments of Members . . - Using Embryonic Stem Cells (ES Cells) to Introduce Mutations Into the Mouse Germ Line" P. M. Saling, Ph.D. Departments of Obstetrics nd Gynecology and Ceil Biology Duke University Medical Center Durham, NC Present wording: New Members of standing committees and Members of ad hoc committees shall be appointed by recommendation of the President-Elect, with the approval of the Executive Council. At least one-third, but not more than two-thirds, of the Members of the standing '-.../ committees shall be replaced each year. The Chairpersons-Elect of the respective standing committees shall be chosen by the President-Elect of the Society from the eligible Members of the pre-existing committees. sociate Members, Trainee Members and Sustaining Associates shall hereinafter be referred to as "Members: except where specifically identified. Proposed wording: New Members of standing committees and Members of ad hoc committees shall be appointed by recommendation of the President-Elect. with the approval of the Executive Council. At least one-third, but not more than two-thirds, of the Members of the standing committees shall be replaced each year. The Chairpersons-Elect of the respective standing committees shall be chosen by the President-Elect of the Society from the eligible Members of the pre-existing committees, where possible. Proposed wording: The categories of· membership in the Society shall be: (a) Regular Member: Any individual who has demonstrated professional competence in and made scientific contributions to the field of reproductive biology shall be eligible for Regular membership in the Society. (b) Member Emeritus: Regular Members who reach normal retirement age or who retire early for medical reasons shall be eligible to petition the Executive Secretary to have the Board of Directors approve a waiver of their annual dues. Such Members shall otherwise by synonymous with Regular Members. (c) Honorary Member: An individual who, based on his/her overall impact on science is a Hartman awardee. (d) Associate Member: Any individual or institution with a scientific interest in the field of reproductive biology shall be eligible for Associate Membership. (e) Trainee Member: Any individual in predoctoral or postdoctorql training in the field of reproductive biology and who has been recommended by a Regular member shall be eligible for Trainee Membership. (f) Sustaining Associates: Any Rationale: This change has been included to reflect more accurately the workings of the Society. Sometimes an eligible Member of the pre-existing committee cannot seNe as chairperson either for personal or for professional reasons. The above is notice of the proposed changes to Articles XI, section 2 and V, section 1 which will be presented at the 1990 annual business meeting for vote by the membership. 4 minireviews and exceptional papers. Minireviews are intended to provide concise information about topics of current importance and/or controversy and are limited to five printed pages. Page charges are waived for minireviews. although authors must pay for any reprints ordered. Exceptional papers are full papers that have received an ~outstanding· rating by two reviewers. Both minireviews and exceptional papers are identified as such in the Table of Contents and are assigned priority status for publication. Authors of exceptional papers are responsible for page charges. As of July 1. 1989 we will send new manuscripts to three referees for critical review rather than to two. Disposition of a manuscript will be made on the basis of two concurring reviews. This policy is expected to facilitate and accelerate the review process. To encourage broader partiCipation and to increase the visibility of BOR internationally. we will recruit more international scientists as referees and as members of the Editorial Board. FAX and BITNET will ensure prompt communications in these cases. We welcome input from the membership. especially with regard to recommendations for new referees. minireviews and suggestions for improving the journal. Also. we ask that the membership' keep in mind that BOR is a peer-reviewed journal. Therefore. decisions of the referees. not members of the Editorial Office. decide which papers will make ~solid contributions· to BOR. We look forward to serving the membership of BOR and to maintaining high standards for publications in BOR. In addition to the above changes in the Bylaws. the Bylaws committee is considering several other changes which we will report in the next newsletter. If any member has any questions or suggestions. please contact me at: Department of Medicine. Peptide Research. Tulane University Medical Center. 1430 Tulane Avenue. New Orleans. LA 70112. (504/588-5847). Mary V. Nekola. PhD. Chairperson. Bylaws Committee Notes from the Editorial Office Dr. Fuller Bazer has taken over as Editor-in-Chief of Biology of Reproduction and the editorial office is in full operation in Gainesville at the University of Florida. Dr. William ~Bill· Thatcher is Associate Editor and Drs. John Davis and David Garbers are serving as Assistant Editors. Patrick Tolley is the new Editorial Coordinator and Judith Jansen is continuing as the Editorial Assistant. All submissions and all correspondence and inquiries should be directed to: Dr. Fuller W. Bazer. Editor-in-Chief Animal Science Department Building 459-Shealy Drive University of Florida Gainesville. FL 32611-0691 Telephone: 904/392-7641 FAX: 904/392-7652 Electronic mail: [email protected] Authors and reviewers are requested to use BITNET for emergency messages and immediate responses to questions. For questions and messages relative to proofs or technical editing please direct those questions to: Public Affairs CommiHee Appropriations for FY 1990 Disappointing and discouraging is the information emanating from Washington regarding the funding of the National Institutes of Health (NIH) including the National Institute of Child Health and Human Development (NICHD) for fiscal year (FY) 1990. Congress initially failed to pass an appropriations bill prior to the October 1. 1989. deadline. thereby necessitating the passage of continuing resolutions to finance the daily activities of the federal government. A joint House/Senate Conference Committee subsequently approved a compromise appropriations bill which included appropriations for the NIH/NICHD for FY 1990. However. that bill (H.R. 2990) was vetoed on October 21. 1989. by President Bush due to his objection to a provision which would have expanded the Medicaid funding for abortions. As a consequence. beginning on October 1. 1989. and continuing until just recently. the funding of the NIH including the Ms. Judith Jansen. Editorial Assistant 1526 Jefferson Street Madison. WI 53711 Telephone: 608/256-3348 FAX: 608/256-3348 Recent Changes and New Policies In our continuing effort to publish the results of important work in reproductive biology as expeditiously as possible. we have enacted a number of new procedures and policies. Beginning with Volume 40. twelve issues of BORwill be published each year (two volumes per year. six issues per volume). The number of issues was in\.J creased to reduce the time than an accepted manuscript is in production. BOR now publishes two new categories of papers: 5 Fig . I 600 Fig- 2 40 35 sso 30 500 25 .50 20 15 400 10 3SO 300 L-,-~--,-- t!S4 0 0 t'85 t9ft6 tlJft7 0 0 o· H88 tm (Est) t!'O (Est) 1985 1986 1981 1988 19" ((stl 1990 (Est) fhcal 'fear NICHD has been by continuing resolutions. Also, since Congress and the President failed to reduce the projected federal deficit for FY 1990 to $110 billion by October 15, 1989, the sequestration provisions (automatic budget cuts) of the Gramm-Rudman-Hollings Budget Reduction Act of 1985 became effective on October 16,1989. The continuing resolutions froze FY 1990 spending levels atthe lower of the House and Senate mark-ups, and sequestration imposed a mandatory 5.3% across-the-board reduction (4.3% reduction for defense spending) below the spending levels required by the continuing resolutions. In terms of the NICHD, the continuing resolutions and sequestration temporarily decreased the FY 1990 budget of the NICHD from the initial Conference agreement of $451 million down to $426 million. During the week of November 20, 1989, and immediately prior to the Thanksgiving Holiday, Congress and the President resolved their differences. An appropriations bill, which included the appropriations for the NIH including the NICHD for FY 1990, was approved and signed into law. As a result, the rescissions resulting from the continuing resolutions and sequestration were alleviated. Although the longterm implications of sequestration for FY 1990 are currently unknown, it is nevertheless clear that the budget for the support of biomedical research by all of the Institutes of the NIH including the NICHD will be extremely tight during FY 1990. In fact, the projections as of this date (December 1, 1989) are that FY 1990 will be one of the worst funding years for biomedical research by the NIH in over a decade. As anticipated, the funding of new and competing renewal grants by the NICHD during FY 1990 continues on a serious decline (Fig. 1). The NICHD will fund only approximately 350 new and competing renewal grants during FY 1990. Last year (FY 1989) the NICHD funded 439 new and competing renewal grants, and during FY 1988 the NICHD funded 450 new and com- peting renewal grants. However, in FY 1987 the NICHD funded a decade-high number of 545 new and competing renewal grants. The decline from FY 1987 (545 grants) to FY 1990 (350 estimated grants) represents a loss of 195 (nearly 36%) in new and competing renewal grant support. However, it is important to remember that only approximately one-third of all research grants funded annually by the NICHD supports research in the reproductive sciences. The remaining grants are distributed among other investigators in the pediatric, biochemical and behavioral sciences. In addition to the decline in the number of new and competing renewal grants which will be funded during FY 1990, there will also be a substantial decrease in the funding rate (Fig. 2). The funding rate (%) for the NICHD for FY 1990 will decrease to approximately 20% of approved grants which will be funded. Since the percentile level of funding is generally 3 to 4 percentage points below the funding rate, the projected funding rate of approximately 20% translates into a percentile funding level at only the 16 to 17th percentile for the NICHD for FY 1990. However, based on recent data from FY 1989, I personally doubt whether the 16 to 17th percentile will be attained by the NICHD during FY 1990. During FY 1989 the NICHD was projected to have a funding rate of 25.3%, which would have resulted in a funding level up to the 21 to 22nd percentile. However, during all of FY 1989 the funding level for the NICHD never exceeded the 17th percentile, and during the last round of funding for FY 1989 the NICHD funded up to only the 13th percentile. Therefore, if FY 1989 seNes as an accurate predictor of FY 1990, I antiCipate that the NICHD will fund at substantially lower percentiles during FY 1990 than were funded during FY 1989. In addition to the anticipated lower number of new and competing renewal grants funded and the lower percentile level of funding, there will also be substantial negotiated reductions for both com pet- 6 \....J ' 1990 the NIH funding rate is prOjected to further decrease to only approximately 24.3% of approved grants which will be funded. Despite all of the disturbing information regarding the prOjected funding of new and competing renewal grants. at the present time the NIH including the NICHD continues to fund a relatively large total number of research grants including both competing and non-competing grants. During FY 1989 the NIH funded approximately 20.600 competing and noncompeting research grants. and during FY 1990 the number of grants funded is prOjected to decrease to approximately 19)00 competing and non-competing grants. However. it is important to realize that the reason for the relatively smaller decrease in the total number of grants funded compared to the total number of new and competing renewal grants which will be funded is due to the large number of non-competing grants which are currently in the pipeline and are still receiving support. There are two primary reasons for the large number of non-competing grants which are currently funded. The mean duration of funding for each funded grant has been increasing through the years. and currently is approximately 4.3 years. Also. a large number of new and competing renewal grants were funded by the NIH during FY 1987 and FY 1988 and are still receiving support. However. all non-competing grants will eventually come up for competing renewal. Therefore. as the total number of competing renewal awards continue to decrease. the number of non-competing grants which will be funded upon competing renewal will also inevitably decrease. The long-term effect will be that if current funding trends continue. in time the total number of research grants funded by the NIH will be considerably reduced. When we examine the bleak outlook for the funding of not only the reproductive sciences by the NICHD during FY 1990. but also the funding of all biomedical research by the NIH. we must ask ourselves how such deteriorated funding situation ever developed. Although the_answers are complex and far-reaching. I believe that I can provide somewhat of a brief inSight. During the Reagan years (1981-1989) there was a substqntial build-up of the United States military. which was the largest build-up ever in peacetime. In addition to a build-up of conventional forces. there also were several extremely expensive defense initiatives funded including the Strategic Defense Initiative (SDI. or "Star Wars") and the B-2 Stealth Bomber. At the same time there were increased outlays for Social Security and other entitlement programs such as Medicare and veterans benefits. All of these were being financed while individual and corporate income taxes were decreasing due to the vqrious Tax Reform Acts of the 1980' s which resulted in de- Membership for SSR Our Society needs your help! Our membership Is growing-but too slowly. The challenge for this year Is for each member to invite one fellow scientist to become a member. Just think. our membershIp would double in one year! Many people never Join an organization because they are never asked/ Janis Bahr ing and non-competing grants for the NICHD during FY 1990. For competing grants the negotiated reductions will be approximately 10%. and for non-competing grants the negotiated reductions will be approximately 14%. In contrast with the serious problems which exists for the funding of individual research grants by the NICHD. Congress was much more generous in its support of research centers. In addition to "get-well* money for NICHD centers. Congress also appropriated funds for one new center in learning disabilities. along with several new child health care centers. The number of centers in the reproductive sciences will remain at 16. while the total number of NICHD centers will increase from 46 to 53. The funds for these centers are contingent upon a non-sequestration budget of approximately $451 million for the NICHD for FY 1990. Although Congress approved a budget of $7.68 billion for the NIH for FY 1990. which is an increase of $539 million over the FY 1989 budget of $7.141 billion. the additional funds are earmarked primarily for specific line items. New buildings and facilities at NIH. and a new supercomputer for the National Cancer Institute. are among the top recipients of the additional funds. No relief was provided for research grants. and as a result the number of new and competing renewal grants which will be funded by the overall NIH will decrease from approximately 5.325 funded during FY 1989 to less than 4)00 funded during FY 1990. In FY 1988 the NIH funded 6213 new and competing renewal grants. and during FY 1987 the NIH funded a decade-high number of 6.447 new and competing renewal grants. The decline in support from FY 1987 to FY 1990 represents a loss of approximately 27% in competing grant support from the NIH since FY 1987. The funding rate (%) for the overall NIH also continues to decline. During FY·1987 the funding rate for the NIH was 38.3% of approved new and competing renewal grants which were funded. during FY 1988 the funding rate was 36.6%. and during FY 1989 the funding rate for the NIH decreased to 29.2%. For FY 7 research activities by writing to speCific members of the House and Senate Appropriations Subcommittees. In the spring of 1989 SSR members sent approximately 1,500 letters to the House and Senate I.....J Appropriations Subcommittees, and in the spring of 1988 approximately 1,100 letters were sent to Congress by members of the SSR. If you have not previously participated in this SSR Congressional mail-in campaign but would like to participate this year, please fill out the enclosed card and return it to me at your earliest convenience. If you previously filled out and returned a card and you were included in our last mail-in campaign, please do not return the enclosed card since you are already included on our mailing list and will automatically receive the necessary materials. creased revenues. The primary consequence of the interaction of these events has been the largest budget deficit ever accumulated in the history of the United States. In order to attempt to address the budget deficit, the Gramm-Rudman-Hollings Budget Deficit Reduction Act of 1985 mandated specific cuts in spending levels to decrease the deficit according to an annual formula. However, approximately 80% of the federal budget cannot be rescinded since it is protected from rescission by federal lows. These protected outlays include outlays for Social Security, military programs already in the acquisition pipeline, Medicare, various entitlement programs such as veterans retirement benefits, and payment on the national debt. In fact, one third of the entire federal budget is currently earmarked for payment of the interest on the national debt. Unfortunately, the NIH budget including that of the NICHD are included in the approximately 20% of federal appropriations which are not protected from the budget-rescission process. The effects of this vulnerability to Congressional rescission are painfully evident when examining the current serious decline in the funding of research grants by the NIH. Public Affairs Activities at the 1989 Annual Meeting in Columbia The Public Affairs activities at our annual meeting in Columbia, MO, were very intense. One of the highlights of our Public Affairs program was the ~Forum on the Federal Funding of Research in the Reproductive Sciences" which was co-sponsored by the Public Affairs Committee and the Student Affairs Committee. A highlight of the Forum was a discussion of the funding of research in the reproductive sciences by Dr. Duane F. Alexander, the Director of the NICHD. Dr. Rosemary R. Grady of the U.S. Department of Agriculture (USDA) discussed the funding program for reproductive research which she administers for the USDA, and Dr. Gary C. Ellis of the Institute of Medicine in Washington, D.C .. provided a stimulating discussion of the interaction of political processes and the funding for reproductive research. I personally provided an update of the continuing decline in the funding for the reproductive sciences through the NICHD. The Forum was co-hosted by Student Representative Anne Miller and myself. We have received excellent feedback from SSR members regarding the Forum, and encouragement to present similar forums in future annual meetings of the SOCiety. There was also extensive media coverage at our annual meeting in Columbia. We had a total of four television interviews and three newspaper interviews. This was byfarthe most extensive media coverage at any of our annual meetings in quite some time. Also, I presented an update on the Public Affairs activities of the SOCiety to the membership at our annual business meeting. Plans are currently underway for another active public affairs program at our 1990 annual meeting in Knoxville. More information will be forthcoming in future newsletters and in public affairs updates. SSR Congressional Efforts The SSR has been among the most active of all scientific societies in attempting to increase the support for biomedical research by the NIH, particularly the support for research in the reproductive sciences by the NICHD. I testified before the House Appropriations Subcommittee on Labor, Health and Human Services, Education and Related Agencies on behalf of the SSR on April 27, 1989. I have also personally made numerous trips to Capitol Hill to meet with Congressional Staff on behalf of the SSR and the reproductive sciences. We are also working in conjunction with other scientific societies to attempt to increase the Congressional support of our research. During this year we will continue to expand our network to include additional scientific societies, and we will also attempt to enlist the support of constituent lay groups in our efforts. As you can see, much has already been accomplished, but very obviously much more still remains to be done. Although the NICHD budget for reproductive research for FY 1990 is disappointing, it would have been much worse without these intensive and extremely time-consuming Congressional efforts. Congressional Mail-in Campaign In April of 1990 we will once again conduct our SSR Congressional Mail-in Campaign. This is an effective mechanism whereby the individual members of our SOCiety have an opportunity to become involved in our grass roots efforts to increase the funding for our Schroeder/Snowe Bill A new bill has been introduced which may be of 8 '-.J r would like to know about new and competing renewals which were not funded. the number of revisions required before a grant was funded. -and any loss of positions or disruption of research activities and careers due to the loss of a grant or due to an inability to obtain grant funding. Include any other information which you feel will be helpful. Also. if you believe that it is appropriqte. please relay the problems which any of your colleagues may have experienced who may not be members of the SSR. Conversely. if-you have been successful in obtaining funding and have experienced little or no difficulties in obtaining funding. please let me know since this information is also of importance. Information which I receive from any individual investigator will be strictly confidential. All information will be tabulated and a general analysis will be made and provided to the membership of our SOCiety. This information will also be very useful to me when I discuss with the House and Senate Appropriations Subcommittees th~ impact which the declining federal support for the funding 'of r~search in the reproductive sciences is having on the members of our SOCiety. This decreased support may not have only current implications. but the effects may also be manifest well into the twenty-first century as young investigators may be discouraged from selecting biomedical research as a career. including research in the reproductive sciences. I will keep you updated regarding the funding situation for FY 1990 in future Public Affairs Updates. In the meantime. please let me know'if you have any questions regarding any of the above items which I have discussed. James P. Preslock. PhD. Chairman. Public Affairs Committee Deportment of Obstetrics. Gynecology and Reproductive Sciences The University of Texas Medical School at Houston 6431 Fannin. Suite 3.204 Houston. TX 77030 713/792-5360 increasing interest to the members of our Society. On July 27. 1989. Representatives Patricia Schroeder (DColorado) and Olympia Snowe (R-Maine) introduced a bill into the House of Representatives (H.R. 2956) entitled the "Birth Control and Infertility Research Centers Act of 1989.· This Bill. if approved and funded by Congress. will establish five new centers within the NICHD. which will include three new centers in contraceptive (birth control) research. and two new centers in infertility research. The first year of funding would be $20 million. with the funding varying during the following four years of support. It is important to note that the funds for these centers would come from supplementary funds provided by Congress to the NICHD and not from other programs currently funded by the NICHD including existing centers. individual research grants (R01·s). or training. The Public Affairs Committee and the Board of Directors of our Society are currently developing an official position for our SOCiety regarding this important legislation. Although the bill appears very attractive since it focuses Congressional attention on two very critical problems important to the reproductive sciences. there are still several serious concerns which the SOCiety must address before taking an 'official position. One important consideration is the inclusion of basic research as an integral part of the centers. A second concern is whether the centers will have any negative impact on the overall Congressional funding of individual research grants (R01's) in the reproductive sciences through the NICHD. However. each individual member of our Society at his or her own discretion may contact his representative in Washington and urge support for this legislation. If you are interested in supporting this legislation and you would like additional information. please contact me at your earliest convenience. Funding Information/Data Base As the Congressional support of research in the sciences through the NIH including the NICHD continues to decline. the negative impact upon the members of our SOCiety continues to increase. I receive frequent reports from the members of the SSR regarding the loss of competing renewal grants. the inability to fund new grants. and the problems which are encountered due to negotiated reductions of funded grants. I would therefore like to initiate a unique program for our Society in which a data base will be established and maintained which will document the impact which the decline in federal research support is having on the members of our SOCiety. If you have been unable to secure funding for your research through the NIHjNICHD despite reasonably high priority scores (Le .• 200 or better) and high percentiles (Le .. 4Oth percentile or better). please let me know. I reproductiv~ Awards Committee The call for nominations for the 1990 Carl G. Hartman Award. the SSR Research Award and the SSR Distinguished Service Award was sent to the membership in early November. The deadline for submission of the appropriate documents in support of each nominee is January 15.1990. It is antiCipated that the membership will nominate several individuals for each of these prestigious awards. The Carl G. Hartman Award is the highest award given by the SOCiety and is in recognition of a career 9 in research and scholarly activities in the field of reproductive biology. The SSR Research Award is given to an individual that is an active. regular member of the Society for outstanding research published during the past six years. regardless of the age of the recipient. The SSR Distinguished SeNice Award recognizes a person who has given unselfish seNice and leadership to reproductive biology. Young investigators are encouraged to apply for the Young Investigator Award if they intend to present a paper at the annual meeting. The application procedure for the Young Investigator Award is explained in the materials for submission of abstracts for the 1990 Annual Meeting of the Society for the Study of Reproduction. Anthony J. Zeleznik. Ph.D. Chairperson. SSR Awards Committee have demonstrations of equipment by manufacturers during the lunch break: i.e .• hPLC. cell sorters and so forth. We need your feedback as to whether this would be of interest to you and what kind of demos \...../ you would like to see. Please contact: Report and Request From the Development Committee Trainee Affairs Jan P. Roser Department of Animal Sdence Meyer Hall University of California Davis. CA 95616 Telephone: 916/752-2918 Thank you. Jan F. Roser. Chair Development Committee Trainee Sponsored Forum This year's forum will be to discuss the topic of industrial vs. academic careers. This topic should be particularly timely. as many of us are facing career decisions. In light of today's problems. including limited funding and the difficulty of finding a permanent position. we owe it to ourselves to be well informed '-....J about alternatives. The Trainee Affairs Committee is currently contacting a variety of prominent partiCipants for this forum. We look forward to seeing you at the Forum in Knoxville! The Development Committee. an ad hoc committee composed of members both from industry and academia is responsible for maintaining a core group of sustaining members and fund contributors. The committee recommends to the Board of Directors steps needed to raise funds for the Society in terms of jOint activities with our industry friends. The committee helps bridge the gap between industry and academia by providing (both) appropriate information concerning jOint activities of the Society or of other events of special interest. Recently. the Development Committee has established exhibitor space for companies who would like to attend our meetings. For the last two years. various companies have exhibited at our annual meetings. In 1988 we hosted 7 companies in Seattle: Baxter Scientific. Hamilton Thorn. Waters. Cryo Resources. Meridian Instruments and Bartels and Stout. Inc. In 1989 we hosted 11 companies in Columbia. MO: T. S. Scientific. W. B. Saunders. Research Products International Corp .. Hitshfel Optical Instruments. Research Triangle Institute. Cryomed. Freyer Co .• Inc .. Emcal Technical Sales. Hamilton Thorn. BTX. and Bio Quaint. We try to place exhibitors in accessible areas such as the poster hall so that those who attend the meetings have a chance to visit with our industry friends. The Development Committee feels that having exhibitors at our annual meetings is not only a good source of revenue for the SOCiety ($300 per exhibitor) but provides us with an opportunity to learn about new technologies and interact with industry supporters. During our last annual meeting. a suggestion was made at the Board of Directors meeting to poll the membership as to whether they would like to Trainee Travel Fund The Trainee Travel Fund. due to the generosity of our members. has money available for travel awards to attend this year's annual meeting in Knoxville. Travel funds are available on a competitive basis to trainees who are presenting abstracts and .demonstrate financial need. In 1988. we gave partial funding to 12 trainee members to attend the meeting in Columbia. and this year we hope to support even more. For further information. contact: Kyle Kramer University of Missouri 158 ASRC Columbia. MO 65211 Telephone: 314/882-7793 Faculty Trainee Luncheon Once again. the Trainee Affairs Committee plans to sponsor the Faculty-Trainee Luncheon. This is an excellent opportunity for students and post-docs to meet with faculty that are working at the cutting edge of our field. in an informal and relaxed 10 r atmosphere. Stay tuned for further information in upcoming mailings. animals, and is sent to individuals who become Associate Sponsors by the contribution of $25.00 (Foundation for Biomedical Research, 818 Connecticut Avenue, N.W., Suite 303, Washington, DC 20006, phone 202/457-0654). The foundation is also a responsible source of videotapes, brochures, books and educational material on the use of animals in research. SSR members should be aware of current proposed federal legislation affecting use of animals in research, and should write appropriate letters to their congressmen and senators. Two bills introduced into the House of Representatives (HR560 and HR3223) post major threats to the future of biomedical research in this country. HR560, the Information Dissemination and Research Accountability Act (Rep. Robert Torricelli, DNJ) would establish a National Center for Research Accountability. The center will determine if any research use of live animals proposed for federal funding is duplicative of any other completed or ongoing research. A determination of duplication would prevent funding. A full text data base of all animal research would also be established. The Torricelli Bill would have high costs that would detract from already limited research funds and is itself duplicative in that it fails to recognize the NIH peer review already safeguards against unnecessary redundancy in animal research._Ple.ase write_a lett.er urging your congressional representative not to co-sponsor the Torricelli Bill (HR560), for the reasons mentioned. HR3223, introduced to the House by Rep. Charlie Rose, D-NC, is called the "Animal Welfare Improvements Act of 1989,· is a new Rose Bill which incorporates all the language of the "standing" bill previously introduced by Rose (HR2345), and would grant any person, on behalf of any animal, the legal standing to sue the federal government to compel enforcement of the Animal Welfare Act. In addition, the new Rose Bill appears to condone research faCility breakins and animal theft. It would legalize acts causing only temporary loss of research animals, and permits many other disruptive acts if any violation of the Animal Welfare Act by the faCility can be proven, no matter how trivial. HR3223 also calls for a study of duplication in animal research, use of alternative methods, establishment of alternative enforcement agencies, and other animal rights oriented goals. The study would be by cabinet officers and leaders of animal rights organizations, without representation from the research community. You should urge your congressional representative not to endorse the new Rose Bill (HR3223). Bill HR2766 from Rep. Edolphus Towns, D-NY, is a bill to "amend the Animal Welfare Act to include mice, rats, and birds: i.e., species not currently covered. The animals currently covered by the act are dogs, SSR Placement Committee We would like to thank everyone that used the Placement Service at the annual meeting in Columbia. Many candidates and employers were brought together, and a number of individuals obtained pOSitions as a result of their participation. The Placement Service will be in operation at Knoxville this summer, and would like to help you find the position or candidate that you need. Look for our announcement in the March or April edition of Biology of Reproduction. Teresa McShane, Trainee Representative, will be running the Placement Committee in 1990. Justin C. Lamsa, Ph.D. Trainee Representative Note From the Animal Care and Use CommiHee The committee continues to view as its primary concern the threat to biomedical research presented by animal rights activists. Of further concern is the apparent lack of awareness and failure to respond on the part of individual reseerchers aAd-educators. The single, major reliable source of information on developments affecting the use of animals in research is NABR-the National Association for Biomedical Research, operating in conjunction with its companion organization, the Federation for Biomedical Research (FBR). We, therefore, urge every SSR member to arrange to obtain copies of NABR mailings through their home institutions, and to also consider individual memberships in FBR. The NABR is supported only by institutional members, including major research universities, professional organizations and biomedical researchrelated companies. It is actively involved in government and congressional relations, and in actively representing member institutions in national policy making affecting the use of animals in research. If your institution is a member, a core group of administrators routinely receives the brief. timely one-page publications-NABR Updates and Alerts. You should contact your administration and arrange to have copies of these resources sent to you on a regular basis. The FRB is supported by individuals as well as institutional sponsors, sponsoring contributions are tax deductible, and the group's role, mission and services are dedicated to public education and distribution , of information on the importance of the use of animals in research. The FBR quarterly Newsletter summarizes news and legislation on research use of 11 or to disrupt or damage the faCility or its activities. This House companion to Senator Heflin's bill is a major advance in the advocacy of the necessary contribution of animals to human welfare and biomedical '-./ research. The co-sponsorship of the Agriculture Committee leaders is particularly favorable. You should urge your representatives in Congress to support the Stenholm Bill (HR3270). House Bill HR334 introduced by Rep Henry Waxman , D-CA, has a similar intention, but it amends the Public Health Service Act ,and its provisions would apply only to animal facilities receiving PHS funds. It would make it a federal crime to threaten, damage or steal from a PHS-funded animal research facility. You should also urge your representatives to support and co-sponsor the Waxman Bill (HR334). Letters to your representatives and senators should, if possible, use the correct office building address and zip code extension, which are available from the representative's local office listed in your phone book or from your local library. They should also be written on letterhead paper, mention your particular situation, the potential harm animal activists can cause in your district, and your willingness to personally assist the legislator's staff on this topiC. The NABR and FBR will provide you with useful information. There is no reason why you cannot send a letter today, right now (samples enclosed). Copies can be sent to the following addresses. Rep. Kika de la Garza , Rep. Edward R. Madigan and Rep. Charles Stenholm, the House Committee on Agriculture, 1301 Longworth House Office Building, Washington , DC 20515; Rep. John D. Dingel. Chairman, House Energy and Commerce Committee, 2125 Rayburn House Office Building, Washington, DC 20515; Rep. Henry Waxman, Chairman, Energy and Commerce Subcommittee on Health, 2415 Rayburn House Office Building, Washington, DC 20515. Letters to your two senators in support of Senator Heflin's S727 can be similarly prepared. The Committee would appreCiate proposals or suggestions from members on topics and speakers for an Animal Care and Experimentation Forum at the 1990 Annual Meeting. These should be forwarded to any of the committee members-Patrick Concannon, Mary Buhr, Kerry Foresman, David Hess, Babetta Marrone, Bruce Moulton, Jan Roser, George Stabenfeldt, Richard Steger and Larry Katz. The committee would also appreCiate any suggestions or information that you wish to have announced in the next note to the members. Patrick W. Concannon Chairman, SSR Animal Cace and Experimentation Committee cats, monkeys, guinea pigs, hamsters, and rabbits , and others as the Secretary of Agriculture may determine. Rats, mice, and blrds are not currently covered , ostensibly because of lack of resources to regulate and inspect the faCilities involved. Most biomedical research organizations have taken a neutral position on this bill. The inclusion of these species will require an extensive increase in funding for the USDA's existing animal welfare program which is managed by the Animal and Plant Health Inspection Service (APHIS) branch of the USDA. Unfortunately, the Towns Bill (HR2766) does not provide the budget authority for including the additional species in the Animal Welfare Act. Interestingly, the USDA has stated that it is now considering developing regulations and standards for rats, mice and birds. House Bill HR2596 (Rep. Robert Smith, R-NH) would order the Secretary of Health and Human Services to transfer the Silver Springs monkeys to non-federal facilities. NIH has already transferred most of the control animals to the San Diego Zoo but legal efforts of animal rights groups are currently preventing NIH from arranging appropriate resocialization programs and euthanasia for the remaining animals. Members of Congress should be urged not to co-sponsor HR2596. The most encouraging developments in p roposed federal legislation affecting research use of animals are the bills introduced to protect animal research facilities, including S727 introduced in the Senate by Senator Heflin, and in the House by Congressmen Waxman (HR3349) and Stenholm (HR3270). Hopefully, such legislation will become enacted and deter animal rights groups from causing major disruptions to research program and gaining undeserved publicity. Senate Bill S727 , sponsored by Senator Howell Heflin (D-AL), is entitled ~The Animal Research Facility Protection Act- and would amend the Animal Welfare Act (AWA) , and apply to facilities covered by the AWA. The amendment would make it a federal crime to steal. destroy, or make unauthorized use of research animals, equipment or data. This appreciation of the need for animals in research is a landmark, and you should urge both your senators to support the Heflin Bill. HR3270, introduced in the House by Rep. Charles Stenholm (D-TX) is entitled the ~Farm Animal and Research Facilities Protection Act of 1989: It was referred to the House Agriculture Committee with 44 co-sponsors, including the Agriculture Committee's Chairman K. de la Garza (D-TX) , and its ranking minority member, Edward Madigan (R-IL). The Stenholm Bill would amend the Food Security Act and protect all animal research facilities and farm animal facilities, and would make it a federal crime to take an animal 12