Pages 5 - Cornea Research Foundation of America

Transcription

Pages 5 - Cornea Research Foundation of America
Annual Report
Fiscal Year Ending June 30, 2011
www.cornea.org
Table of Contents
Page 3 - 4
Message from Marianne Price,
PhD Executive Director &
Francis W. Price, Jr., MD, Founder
and Chairman
Pages 5 - 6
Treasurer’s Report
Page 7 - 12
Donor Acknowledgement
Page 13 - 14
Featured Research
Page 15 - 16
Award Winning Research
Page 17 - 18
Special Events
Page 19 - 22
Publications and Meetings
OUR MISSION:
TO B E A
WO R L D -
CLASS
RESEARCH
A N D E D U C AT I O N A L
O R G A N I Z AT I O N ,
D E D I C AT E D TO T H E
P R E S E RVAT I O N
About this Report
The achievements featured within this report, along
with the goals outlined for the future growth showcase the dynamic research strategies underway at the
Foundation. We work to develop and refine
cutting-edge procedures and techniques to restore
sight and faith for individuals around the world.
A N D R E S TO R AT I O N
OF
VISION.
Your donations help restore sight.
About the Foundation
As a 501(c)3 not for profit founded in 1988, the Cornea Research Foundation of America,
is an award winning, internationally recognized research and educational organization,
dedicated to the preservation and restoration of vision and known for conducting clinical
studies to evaluate new drugs, lasers, devices and treatments. We measure our success
based on four pillars: Research, Innovation, Service to Humanity, and Education, summarized
in the acronym RISE. Our goal is to continually find new and better ways to give people
back the use of their eyes so they can attend school, make a living, and support their family. We share our findings through frequent presentations, publications and medical educa-
W W W. C O R N E A . O R G
tion courses so that patients throughout the world can benefit from our findings.
A Message from the Executive
Director
What an exciting year! Our work has attracted international recognition - we were invited to share our cornea transplant findings at major
eye meetings in Europe, Asia and South America. We were fortunate to
have two gifted cornea specialists, from leading eye centers in Brazil and
Singapore, join us for one-year research fellowships. Dr. Guerra and Dr.
Anshu were incredibly productive and their work on improved cornea
transplant techniques resulted in 12 publications in leading eye journals.
In addition, we were honored to receive the prestigious Santa Caterina
d’Oro award for excellence in medical research, at a lovely ceremony
held annually in the historic town of Siena, Italy.
We envision a future where corneal problems are detected and treated early, before leading to serious vision loss. We are making steady progress toward this goal by identifying the underlying genetic
causes of Fuchs dystrophy. This work should ultimately lead to early detection and innovative treatments. In addition, we are having good results with an investigational corneal strengthening treatment that can help preserve the vision of teenagers and young adults who have a condition known
as keratoconus.
Collaborating with other centers around the country, we detected a surprisingly high incidence of
antibiotic-resistant bacteria on the surface of the eye and eyelids of patients scheduled for cataract
surgery, clearly demonstrating the need for new and improved antibiotics. To help address this
need, we are among a select group of centers pioneering the use of an innovative light treatment to
kill organisms that cause eye infections. Some of the most serious eye infections occur in young
people who wear contact lenses for extended periods of time, and we are finding this treatment to
be very helpful for these young folks.
We are proud that Working Vision, the fledgling organization we helped nurture the past several
years, has recently taken flight and achieved independent non-profit status. Working Vision is the
brainchild of Grant Moore, one of our former summer interns who later spent a summer working
at a large eye clinic in Kathmandu, Nepal. While there, he was amazed at the number of patients
with serious eye injuries that could have been prevented with proper eyewear. So he initiated a program to collect new and gently used safety eyewear in the USA for distribution in Nepal. Working
Vision continues to expand in scope and now provides eye safety programs and vision screenings, in
addition to distributing safety eyewear. It’s been an honor for us to support these efforts.
Helping people regain vision and resume daily activities is an immensely rewarding endeavor.
We appreciate the generous support of our donors and the dedication of our staff that makes this
possible.
Sincerely,
Marianne O. Price, Ph.D.
Executive Director
This last year represented the 22nd year of the Cornea Research Foundation of
America, and it was a year of major achievements. Achievements ranged from
discovering that a new ultra-thin corneal transplant has 15 to 20 times less risk of
developing a rejection episode than earlier types of corneal transplants, to for the
first time, describing the proteins in the anterior part of the eye which may be
responsible for causing corneas to turn cloudy after glaucoma surgery. We also
were able to accumulate more revenue through donations and study-related income to fund our research activities. Since our foundation does not receive
funding from the federal government, these contributions are essential for what
we do.
An often used saying is that with great gifts come great responsibility, and we
take our gifts very seriously. The Foundation is embarking on an ambitious research path that has the potential to dramatically change the way we approach vision correction, transplant
treatments, and management of those with complicated glaucoma problems.
Because of our ongoing corneal transplant data base, the largest one in the Western Hemisphere, we can
compare rejection rates between standard full thickness corneal transplants, DSEK transplants, and the new
ultra-thin DMEK grafts. We recently found that the chance of having a rejection episode is15 times less for
DMEK than DSEK, and 20 less in comparison to a full thickness transplant. Topical corticosteroids, the antirejection drops we use after corneal transplants cause about 1/3 of patients to develop glaucoma in the first
year after receiving a transplant. Since DMEK appears to have a significantly reduced rate of rejection, the
Foundation is sponsoring a multi-center, international study to evaluate two different corticosteroid dosing
regimens to see if we can reduce the rate of developing glaucoma without increasing the rejection rate. No
one has ever done a prospective study evaluating different topical corticosteroid dosing regimens for corneal
transplants even though it is the most common tissue transplant in the U.S. for over 60 years. And like all
medications used with corneal transplants, it is an ―off label‖ use of the drops – so the FDA told us we had to
file for investigational drug exemption (IDE) study with them – which we have.
The Foundation is sponsoring a prospective, 3-year study with both national and international study sites evaluating patient satisfaction and visual difficulties with different vision correction methods. Other than glasses,
contact lenses and Lasik are the two most common ways to correct vision. No one has ever taken on a study
to evaluate how satisfied patients are with these means of visual correction and what their visual difficulties
might be. Industry is reticent to do this I suspect due to liability and regulatory concerns. The government,
well, they seem preoccupied with other things right now. From a public health standpoint and planning for future correction of vision, this study is very important and should lead to identification of areas of improvement
for both contact lenses and Lasik. We hope to enroll between 2 and 5 thousand patients. Funding will determine the number we can enroll.
Finally, our third major area will be looking at fluid taken from the front part of the eye to help determine why
some patients, like those with glaucoma filters, have damage to the endothelial cells on the inside of the cornea and to see what is happening in eyes with rejection episodes. Our hope is to develop focused, more effective treatments for both of these problems
Each of these three studies are major undertakings, and each has the potential to make landmark changes in
the way we treat diseases of the eye. Your gifts and support make all of this possible. Thank you!
Francis W. Price, Jr., MD
Founder and Chairman
A Message from the Chairman
Treasurer’s Report
by Walter C. Gross, Jr.
The Cornea Research Foundation of America had a great
year. Total revenue for the
fiscal year ended June 30, 2011
was $742,510. In comparison
to 2010, we saw an increase
due to substantial growth in
clinical study earned income.
Our In-Kind Contributions
were also much higher than in
years’ past, thanks to services
generously donated by many
doctors.
We are careful with our
expenses, and for that reason
89% of our operating budget
directly funds research and education programs.
Revenue
Expenses
1%
Guidestar and the Better Business Bureau’s Wise Giving
Alliance have certified that the
Foundation meets their Charity
Accountability Standards.
5%
5%
27%
24%
6%
Contributions
Research and
Education
Service Related Income
Development
In-Kind Contributions
Special Events
Administrative
Interest and Other
Walter C. Gross, Jr.
Treasurer
43%
89%
We thank our generous supporters.
John C. and Bette B. Miller
Charitable Foundation
Marilou L. Dickey
Anonymous
Jack and Jane Donadee
Wayne and Linda Adams
Essilor of America, Inc.
Rider Insurance Agency
Fairfield Engineered Drive Solutions
Akers Tire Company, Inc.
Michael and Jeanette Garvey
Mohammed Al Marar
Chloe Alyce Hughes
Applied Engineering Services Inc.
Audrey Ingram
Joseph and Barbara Barker
Joe Kack
Canfield Lions Club, Inc.
Richard and Barbara Justice
Ryan Cole
Harold Laut
Melvin and Frances Davis
M&I Bank
Bud DeCleene, OD
Marco
Frank and Beverly Deramo
Carl Zeiss Meditec, Inc.
John Devine
Oasis Medical, Inc.
George and Alpha Dinkel
Craig Olson
EAH-JJK Properties, LLC
LensTech Optical, Inc.
Philip and Patricia Gibson
Jeffrey and Laurie Potrzebowski
Robert and Cynthia Grimm
Marijke Raju
Stephen J. Hackman
Cheryl Sokoll
Jeffrey King
STAAR Surgical Company
Richard King
Partners
Schwarz Partners, LP
Lewis Liggett
Stanley and Barbara Schwartz
Gifts from $500 to $999
Holly and Dennis Lewton
Shirley and Erwin Zimmerman
Doug and Carol Moore
The Semler Family Foundation
Gem-Young Insurance & Financial
Service, Inc.
Goelzer Investment Management
Founder
Lehmann Eye Center
Anonymous
Gaughan Family Foundation
The O’Conner-Campion Family
Charitable Fund
Bill Grube
Tom D. Kievit
Joseph and Geraldine La Motta
W.H. Voll
Gifts from $5,000 to $9,999
Fredric and Myrna Gershon
Walter and Janet Gross
Limberg LASIK Institute
Milauskas Eye Institute
Jewish Communal Fund
LaserVue
Frederic and Frances Nathan
Price Vision Group
Dr. Francis W. Price, Sr.
Schneider Vision
San Antonio Eye Specialists
Kenneth Swedo
Bluestein Custom Vision
Wilton J. Johnson
Fellows
Gifts from $1,000 to $2,499
Kenneth Anderson
Huntington National Bank
Benefactors
Gifts from $2,500 to $4,999
Transplant Bank
Gordon & Weiss Vision Institute
Bucci Vision
Patrons
Indiana Lions Eye and Tissue
Buckley Chang Eye Institute
Joseph M. & Barbara Cohen Foundation, Inc.
Gifts from $10,000 to $24,999
Homewood Suites—Keystone
Eye Center of North Colorado
Gifts $25,000 or greater
Humanitarians
Jerry Grage
Calumet Lubricant
“Thank you so much
for all your time, effort
and professionalism
during all my
questions, phone calls
and visits. You were
awesome!
It would have been
impossible to decide on
crosslinking without
your knowledge and
information you shared
with me. You have a
great team!”
Joseph Benitez Jr., MD
Lenore Anderson Endowment
Kathryn Lumb
Shirley Mitchell
William and Margaret O’Conner
Ron Roach
Synergeyes
The UPS Foundation, Inc.
Norwood A. Whitfield
Joseph and Kay Wiley
Donald and Janet Baumgartner
Peter Burchanowski
Roland and Pat Chastain
Friends
Gifts from $250 to $499
Michael Mullen
Marsha Murman
Gregory and Robin Pemberton
Joseph and Deborah DeRanieri
Sherry and Douglass Abney
Adam Reising, OD
Michael Dickerson
Accenture
Ronald G. Salatich
- Donna L.
Marvin Cave
David and Laurie Hill Chapman
Carter Eye Center
Sidney and Lois Eskenazi
Katzen Eyecare and Laser Center
Eye Physicians, Inc.
Without you, we could not do what we do.
We thank our generous supporters.
Vincent Wagner
Rick Bruno
Garry and Diane Warner
Phillip & Shirley Buchanan
Roy Michael Whetstine
Theodora Callas
Carolyn Mock
Marcus and Marylou Winslow
Claire Cartmell
James and Doris Morton
Thelma J. Woodring
Susan Cassudakis
Christine and Edward Muransky
Jack and Florence Wright
Harold Chambers
Friends (continued)
Gifts from $100 to $249
Friends (continued)
Thomas Boone
Steven and Leslie Gordon
Frederic and Jane Nott
Paul Wussow
Timothy and Susan Cianciola
Gifts from $250 to $499
Fred and Ellen Boso
Wayne and Marilyn Greve
John and Toula Oberlies
Connie Zambelli
Linda Cline
Scheid Realty
Fred and Sandra Brown
Maurice Hahn
Elizabeth Pasut
Noha Khouri
James and Pearlie Corbitt
Jay and Mary Sue Schwartz
Michael Bruno
James and Jean Harrington
Edwena Payne
Joumana Seifeddine
Vera Cox
Harold A. Sherline
Carmen Bullock, OD
Robert and Amy Hendricks
Albert and Audrey Pekelney
Joseph and Chery Crum
Bob Smelser
Timothy Buren
Diane Hido
John Peters, MD
William Stifle
James and Charlotte Butler
Robert and Elizabeth Hiller
Angela and Francis Pierce
Friends
Billy and Natalie Cupler
Janet and Gary Taylor
Robert and Mary Ann Campbell
David Huse, DVM
Larry and Jessie Rash
Gifts up to $99
James Daprile
Temp Control Service
Laverne and Ruth Ann Clingenpeel
Linda and Richard Hutchinson
Judith A. Ratliff
Carmela Abraham
Kimberly Davis
Jeffrey Thacker
Bopp-Busch Manufacturing Company
Jack Frisch & Associates
Reddington Christian Church
John Arditi
Chris and Cheryl DeHoff
Trendy Trousseau LLC
Mary Conners
Jostad Enterprises
Roger Reichmuth
Peter and Sharon Asimakopoulos
Susan Domer
Marie Cormican
Kathy Kelley, OD
Jack and Joetta Riggin
Neal and Suha Atway
Linda Eyer
Friends
Patricia Cowan
Betty and Robert King
Salem Women’s Care, Inc.
Mr. and Mrs. Jack J. Baker
Samuel Faccioben
Baker and Daniels
Fred and Vicky Kline
Harry W. Scheid
Lucina Barnum-Steggerda
James and Martha Fairfield
Gifts from $100 to $249
Joseph Daprile
Seneca One Realty, LLC
Larry Sebeckis
John and Mary Battaglia
Gerald Fallon
Dr. Keely Allen
Victor Daprile
Dr. Alfons Landwehr
Deborah Shepherd
Howard and Carla Beeson
Drew Fasseas
Mary Alice Andrews
David and Linda Daringer
Jack and Joan Lane
James and Mary Shepherd
Lester Beisner
John Fazzone
Anna Mae Lane
Ted and Janet DeGarmo
Judith Lasky, PhD
Helaine Simon
Virginia Belcher
Timothy and Ruth Franklin
Donald and Michele Argay
Myron and Nancy Dickerson
Eli (Ted) Lilly II
Howard Steiner
Betty Belschwender
Margaret Freeman
Leland and Carol Ballard
Steven Doi, OD
Guy and Arleen Lucci
John and Eileen Takach
Stephen and Cynthia Bennett
Tonya and Brian Frost
Richard and Karen Banning
Harry Donovan
James and Theresa Maciver
Patricia Thomas
Julie Benson
Royce Garrett
Sadie Barger
Robin Felkins
Gayle Mason
Sherill and Delbert Thornburg
Mark and Michelle Billy
Cecelia Gastelum
Jeffrey Barnaby
Sheila Fiala
Robert and Alana Mauzy
David and Joyce Thurman
Daniel and Rosemary Blilicki
Karen Giorgetti
Duane and Nancy Bassett
Timothy M. Fischer
Alan and Margaret McCall
George and Angela Tzakis
Paul and Jayne Boucherle
Sydelle Golub
Beckwith, Daprile & Co.
JP Morgan Chase Foundation
Rue and Carolyn McFarland
Michael and Rebecca Unfried
William W. and P.A. Bromer
William P. Goodman, III
Larry and Sue Bennett
John Frank
Ralph Michalec
Colleen Vella
Brent Brown
Brian and Melinda Governor
Jeffrey Boller
William Golfsmith
Wendy Mickler
Earl and Martha Vogt
Susan Taracuk Brown
Dorothy Grainger
Anthony and Amy Daprile
We thank our generous supporters.
Friends (continued)
Gifts up to $99
Steven and Sally Warden
Lisa and Andrew Weiss
Phillip and Jacquelyn Weybrant
Friends (continued)
Lucinda Barnum-Steggerda in honor of Robert Barnum
Seneca One Realty, LLC in honor of Jane Kelsch
Mary Lynn McIntyre in memory of Charlie Anne Newton
Paul Whitehead
Michael Kovatch
Stepheny and James Pisciuneri
Mark and Georgia Wilson
Matthrew Kusy
William and Debra Pisciuneri
Thomas Green
Barbara Woerner
Joseph and Mary Jo Lenefonte
Richard Preske
Donna Griesmer
James Wood
Amanda Lopez
James and Julie Rafoth
Joan Hackler
John Yerian
Anne-Marie and Mark Luchansky
Lee Rasamny
David and Traci Hardy
Jaime and John Yohman
Steven and Palan Lussier
Glendolyn Rhymer
Jennifer and Paul Harris
Anthony and Concetta Young
Neva Maloy
Bessie and Melissa Rice
Max and Eldred Hauk
Lynn Scarnati Zvara
Dawn Marzano
Mark and Nancy Sabol
Michael and Marsha Hile
Michael Thomson
George and Beverly Mattox
Michael Schaub
Carol Hinkle
Annabelle Willett
Donnalou and Patrick McVay
Kurt Schwant
Dale and Jo Ann Hoepf
Virginia L. Merillat
Daniel Schwartz
Sarah Hoover
Jemilla Kidanu Michael
Connie Shepherd
Marceda Hosted
Helen Miller
Charles and Shirley Shoppell
Robert Hotchkiss
Norman T. Mills
Rita Sibert
Pamela Hudson
Annabella and Dominador Miranda
Robert D. Sipress
Dorothy Ann Hummel
Toby and Janet Mirto
Catherine Slovan
John W. Hussey
Richard and Cherie Mize
Marlyse Spicer
Samuel Jacobs
Kamel Muakkassa
Erwin F. Springer
David and Michelle Jakovina
Joyce Nevil
Stanich SCP
Greg Jansen
Elaine and Donald Newman
Pamela Steinhauser
Jaime Jarvis
David and Candice Niederhaus
Phil Stuart, OD
Doris M. Johmann
Richard and Nancy Novotny
Marilyn Sullivan
Myron and Rose Jane Kaiser
Vilma Ortiz
Doris Szijj
Megan and Roland Kaleel
Asha and Sushil Pandhi
Joseph and Debbie Thomas
Carol Kalp
Martin and Teresa Papai
Judith Thomas
Julie Kamenitsa
Richard and Phyliss Paul
Tunno Insurance Agendy
Roger and Ellen Kinsey
Patricia A. Peters
Nancy and Michael Vince
Gifts up to $99
Honor and Memorial Contributions
Study Related Income
Alcon Laboratories
ISTA Pharmaceuticals
Allergan
Jaeb Center for Health Research, Inc
Avedro
Patient Education Concepts/CRM
Case Western Reserve University
Trial Runners, LLC
Cook Pharmaceuticals
University of Illinois– Chicago
Inc Research, Inc.
You help make better
vision possible.
Key Research Areas
Preventing Cornea Transplant Rejection
DMEK—The Latest Advancement
in Cornea Transplants
One of the biggest risks transplant recipients face is
that immunologic graft rejection will cause the new
Exciting News
donor cornea to fail. Corticosteroid eye drops are
Decreased risk of rejection from 12 percent to less than 1 percent!
typically used for months or even years to prevent
cornea transplant rejection. Unfortunately, these eye
drops have some serious side effects. Surprisingly, no
prospective randomized studies have been done to
determine the best corticosteroid-dosing regimen, so
solid evidence on what is the best dosing for transplant
patients is lacking. We have found that the new,
minimally invasive transplant procedure called DMEK
has a very low risk of rejection. So we have initiated a
large study to see if we can reduce the topical
corticosteroid strength, and avoid some of the steroid
side effects, while maintaining a low risk of rejection
after DMEK. We will enroll 440 patients in the study
Corneas are about the thickness of a credit card and are comprised of three distinct layers. Although
corneal problems are usually localized to just one or two layers, the traditional approach was to replace
them all. In Figure 1 below, the arrow is pointing to a single line—this is the thickness of a cornea
transplant using the DMEK technique. In Figure 2, the overall length of the red arrow represents the
thickness of a full thickness transplant.
Dr. Price helped pioneer cornea transplant techniques that replace only the diseased portion of the
cornea, leaving healthy layers intact. Only the ultra-thin cell layer lining the inner surface of the cornea
is diseased in about half the patients who need a transplant. According to Dr. Price, ―Replacement of
the inner cell layer with a single cell layer from a donor cornea (a technique known as DMEK) provides
much better and faster visual recovery than earlier methods.‖
The reason cornea transplants fail is because the recipient’s body can recognize the donor tissue as foreign and mount an attack against it. Our research has found that single layer DMEK grafts are 15- to 20
-times less likely to be rejected than earlier techniques that include two or more layers of the cornea.
According to Dr. Price, ―99% of our DMEK recipients remain rejection-free at two years and beyond.
Having a transplant technique that can better elude rejection is a huge breakthrough for cornea transplant recipients.‖
and follow each patient for one year. This landmark
study will provide valuable new information to help
cornea transplant recipients maintain newly restored
vision.
FIGURE 1
DMEK
FIGURE 2
Full Thickness Transplant
Each year approximately 42,000 Americans need a
transplant to replace the cornea, the clear window on the
front surface of the eye. Cornea transplants usually remain
clear for at least 10 years, but in some patients they fail
much sooner. We are working to figure out why transplants
sometimes fail early and to develop innovative treatments
to extend transplant survival. We are doing this by
removing and analyzing fluid from inside the eye, called
the aqueous humor. The fluid bathes the back surface of the
cornea and provides key nutrients that help maintain the
health of the cornea. In this study we will identify the
changes that occur in this fluid when a cornea transplant
starts to fail. This study will provide key information
needed to help maximize cornea transplant survival.
We’re evaluating up to 360 subjects.
Key Research Areas
Key Research Areas
Improving Cornea Transplant Survival
In earlier studies, we found that patients who have had
glaucoma surgery are at particularly high risk for early
cornea transplant failure, and we identified some intriguing
changes that occur in the fluid inside the eye after glaucoma
surgery. We are following up on these promising
discoveries by collecting and analyzing aqueous humor
samples from cornea transplant recipients who are at
increased risk of graft failure either because they had prior
glaucoma surgery, they had an acute immunologic graft
rejection episode, or they experienced a sudden loss of
cells from the back surface of the cornea for unknown
reasons. Fluid samples collected from uncomplicated eyes
with a previous corneal transplant serve as controls.
Vision Correction Method Study—
LASIK/Contact Lenses
The Foundation is conducting a national clinical survey study
comparing visual results, patient satisfaction and quality of life
issues as they relate to LASIK and contact lenses. This is the first
prospective study to follow these two popular methods of vision
correction for nearsightedness, astigmatism, and farsightedness
simultaneously.
Patient consents and surveys are conducted over the internet
using a HIPAA compliant web portal that will automatically
coordinate future patient surveys at the one, two and three-year
anniversaries of the study date of entry.
Our goal of the study is to enroll between 2 and 5 thousand
patients - both those undergoing LASIK, and patients who will
continue to wear contact lenses. We will determine if visual
satisfaction, visual complaints and safety – as reported by
participants – are similar or different between the two groups.
Study sites throughout the United States are currently enrolling
patients in the study.
For a complete listing of our
current studies,
please visit www.cornea.org and click on
Research and then Current Studies.
Foundation Staff
Award Winning Research
Board of Directors
Marianne O. Price, Ph.D.
Drs. Price receive Santa Catarina Award in Sienna, Italy
Francis W. Price, Jr., MD
Founder and Chairman
Executive Director
Jessica Dingledy
Development Director
Clorissa Quillin
Research Coordinator
Kelly Fairchild
Research Coordinator
Maraya Baumanis
Research Intern
Lauren Gunderson
Research Intern
Francis W. Price, Jr. , MD and wife
Marianne Price, PhD were presented with
the ―Santa Caterina Oro Città di Siena‖
International Prize on February 27, 2011
in Siena, Italy. Drs. Price traveled to Siena
and were honored at the ceremony receiving the Santa Caterina gilded statue at
the Teatro dei Rozzi in Siena.
Francis W. Price Jr., MD of Price Vision
Group is the founder and president of the Cornea Research Foundation of America,
and his wife, Marianne is the Foundation’s executive director. Together they were chosen as recipients of the Santa Caterina prize as their research has led to significant improvements in cornea transplant surgery and treatment of eye diseases around the
world.
Each year, ten recipients from different areas of expertise all over the world are selected to receive this prestigious award. The Prices commented, ―We feel blessed to have
found better ways to give people back the use of their eyes and to have had the opportunity to share improved techniques with eye care professionals nationally and internationally.‖ For more information, visit http://www.cornea.org.
F. W. (Bill) Grube
Vice President
Trischa L. Zorn-Hudson
Secretary
Walter C. Gross., Jr.
Treasurer
Jim Butler
Frank Clifford
Michael W. Dickerson
Phil Gibson
Robert Grimm
David C. Huse
Toula Oberlies
Jerry D. Semler
Events
Focus on Education Optometrist Seminar
November 2010
Each year the Foundation sponsors an all-day seminar for
optometrists that features programming on the latest
treatments and surgeries available for the anterior segment
of the eye and cornea. Attendees earn approved continuing
education credits while learning about the newest ophthalmic
medical devices, pharmaceuticals, and practice management
techniques.
The Foundation would like to thank all of
those who served on our Cornea
Classic Golf Committee for organizing a successful golf outing on June 2,
2011 at Wood Wind Golf Club in Westfield, Indiana. The event raised nearly
$28,000 to fund our mission to provide
research and education to preserve and
restore vision. Thanks to all who donated,
sponsored and participated in the event.
The outing will be held on June 21,
2012 next year. If you would like to
receive the registration form in February,
give us a call at 317-814-2993.
Golf Committee
Harry W. Scheid
Chairman
Vern Rensing
Vice Chairman
Pat Chastain
Mike Dickerson
Phil Gibson
Walter C. Gross, Jr.
Mark Horton
Joe Kack
Francis W. Price, Jr.,
June 2011
Cornea Classic Golf Outing a Success
PUBLICATIONS
Guerra FP, Price MO, Price FW. Is central pachymetry asymmetry between eyes an independent risk factor for ectasia after LASIK? J Cataract Refract Surg 2010;11:2016-7.
Letko E, Price DA, Lindoso EM, Price MO, Price FW. Secondary
Between July 1, 2010 and June 30, 2011
graft failure and
repeat endothelial keratoplasty after Descemet's stripping automated
endothelial keratoplasty. Ophthalmol 2011;118:310-4.
Hayes DD, Shih CY, Shamie N, Terry MA, Price FW Jr, Price MO, Ritterband DC, Hannush SB,
Gorovoy MS, Weisenthal RW, Ritch R, Liebmann JM, Udell IJ. Spontaneous reattach-
Click on the blue hyperlinks to read each publication.
Price FW, Price MO, Arundhati A. Descemet
stripping automated endothelial keratoplasty under failed penetrating keratoplasty: how to avoid complications. Am
J Ophthalmol 2011;151:187-8.
Olson R, Donnenfeld D, Bucci FA, Price FW, et al. Methicillin
resistance of Staphylococcus species among health care and nonhealth care workers undergoing cataract surgery. Clin Ophthalmol 2010;4:1505-1514.
Da Reitz Pereira C, Guerra FP, Price FW Jr, Price MO. Descemet's
membrane automated endothelial keratoplasty (DMAEK): visual outcomes and visual quality. Br J
Ophthalmol 2011;95:951-4.
Richardson MR, Segu ZM, Price MO, Lai X, Witzmann FA, Mechref Y,Yoder MC, Price FW. Al-
terations in the aqueous humor proteome in patients with Fuchs endothelial
corneal dystrophy. Molecular Vision 2010; 16:2376-2383 http://www.molvis.org/molvis/
ment of Descemet stripping automated endothelial keratoplasty lenticles:
a case series of 12 patients. Am J Ophthalmol 2010;150:790-7.
Price MO, Price FW. Deep
thalmol 2010;94:1275-6
anterior lamellar keratoplasty: coming of age. Br J Oph-
Price MO, Price FW. Descemet
mol Clin 2010;50:137-47.
membrane endothelial keratoplasty. Int Ophthal-
Price MO, Price DA, Fairchild KM, Price FW. Rate
and risk factors for cataract formation and extraction after Descemet stripping endothelial keratoplasty.
Br J Ophthalmol 2010;94:1468-71
Kwon RO, Price MO, Price FW, Ambrosio R, Belin MW. Pentacam characterization of corneas with Fuchs dystrophy treated with Descemet membrane endothelial keratoplasty. J
Refract Surg 2010;26:972-9.
v16/a255
McCauley MB, Price MO, Fairchild KM, Price DA, Price FW. Prospective
study of visual
outcomes and endothelial survival with Descemet membrane automated
endothelial keratoplasty. Cornea 2011;30:315-9.
Price MO, Fairchild KM, Price DA, Price FW. Descemet's
stripping endothelial keratoplasty five-year graft survival and endothelial cell loss. Ophthalmology 2011;
118:725-9.
For a complete listing of our publications,
please visit www.cornea.org and click on
Research and then Publications.
MEETING PRESENTATIONS
Between July 1, 2010 and June 30, 2011
Eye Bank Association of American Annual Meeting,
Tucson, AZ, June 2011.
Price MO, Gorovoy M, Benetz BA, Price FW, Washington K, Debanne S, Menegay H, Lass J. DSAEK outcomes at three
years compared with penetrating keratoplasty from the Cornea Donor Study. Eye Bank Association of America
Scientific Session, June 25, 2011, Tucson, AZ.
Soper M, Price MO. Eye bank preparation of DMAEK tissue (DMEK with stromal ring).
West Virginia Academy of Eye Physicians & Surgeons annual meeting,
White Sulfur Springs, WV. June 2011
Price FW, Price MO. The current state of the art in corneal crosslinking.
Price FW, Price MO. Anterior lamellar keratoplasty..
Price FW, Price MO. Evolving surgical techniques in endothelial keratoplasty.
Price MO, Price FW. Glaucoma/IOP control, topical corticosteroid use, and immunologic graft rejection with endothelial keratoplasty.
Price MO, Price FW. Management of cataracts in patients with Fuchs’ dystrophy.
Price MO, Price FW. Long term endothelial keratoplasty survival and risk factors for graft failure.
Association for Research in Vision and Ophthalmology annual meeting,
Ft. Lauderdale, FL. May 2011
Price MO, Anshu A., Price FW. Outcomes of endothelial keratoplasty under failed penetrating
keratoplasty.
American Society of Cataract and Refractive Surgery annual meeting,
San Diego CA, March 2011
Guerra F, Price MO, Price FW. Fellow eye comparison of DSAEK and DMEK. (Best Cornea poster award).
Arundhati, A, Price MO, Price, FW. Descemet-stripping endothelial keratoplasty survival outcomes in eyes with preexisting glaucoma.
Guerra F, Ambrosio, R, Price MO, Price FW. Preliminary results of enhanced ectasia screening of refractive surgery
patients based on corneal tomography.
Arundhati A, Price MO, Price FW. Outcomes of endothelial keratoplasty under penetrating keratoplasty.
Planchard B, Price MO, Price FW. Retained viscosurgical device as cause of interface haze after Descemet-stripping endothelial keratoplasty.
Price FW, Price MO. Setting new benchmark for LASIK.
Societa Italiana Trapianto di Cornea annual meeting,
Bologna, Italy, February 2011
Price FW, Price MO. Ten years experience with endothelial keratoplasty. (Keynote lecture).
Price MO, Price FW. Long term visual outcomes and graft survival after DSAEK. (Keynote lecture).
International Innovation Technology Meeting,
Mendoza Argentina, December 2010
Price FW, Price MO. New indications for corneal collagen cross linking.
Price FW, Price MO. Endothelial keratoplasty under failed penetrating keratoplasty: how to minimize
complications.
Price FW, Price MO. DMEK and DMAEK: patient selection and how to optimize visual results with
endothelial
keratoplasty. (Keynote lecture).
Price MO, Price FW. DSAEK long-term graft survival and comparison with PKP. (Keynote lecture).
Price MO, Price FW. Impact of glaucoma on DSAEK: is it different from PKP?
Price MO, Price FW. What has been learned about graft rejection?
Asian Cornea Society Bi-annual Meeting,
Kyoto, Japan, December 2010.
Price FW, Price MO. Endothelial Keratoplasty Overview: where are we now and where are we going?
(Keynote lecture).
Price FW, Price MO. Long-term Outcomes of DSEK/DSAEK. (Keynote lecture).
Price FW, Price MO. Surgical tips for DMEK and DMAEK.
Price MO, Price FW. What have we learned about IOP control and outcomes in DSEK/DSAEK eyes with
and without glaucoma?
Price MO, Price FW. Outcomes of DMEK, DMAEK, and eye bank prepared DMAEK grafts.
Cornea Society/EBAA Fall Educational Symposium,
Chicago, IL, October 2010.
Price MO, Soper M, Price FW. Use of eye bank-prepared donor tissue for Descemet membrane
automated endothelial keratoplasty (DMAEK).
Price FW, Price MO, Guerra F, Schrier A. Prospective randomized trial of cross-linking for infectious
keratitis.
Guerra F, Price MO, Price FW. Fellow eyes comparison of DSAEK and DMEK.
American Academy of Ophthalmology annual meeting,
Chicago, IL, October 2010.
Price MO, Price FW. Do Larger Descemet Stripping Endothelial Keratoplasty Grafts have Better
Long-term Endothelial Cell Density? (Best poster award).
European Society of Cataract and Refractive Surgery
annual meeting,
Sept 5, 2010, Paris, France.
Price FW. Outcomes with Femtosecond laser assisted corneal transplants over a 4.5 year period.
Price MO, Price FW. Five year graft survival of Descemet stripping endothelial keratoplasty.
Price FW, Price MO. Prospective multi-center analysis of 1-year outcomes with DMEK.
Price FW. Cross linking for the treatment of corneal infections.
Price FW, Price MO. DSAEK: five-year results.
Aegean Cornea Congress,
Crete, Greece, July 2010.
Price FW. Current Status of Posterior Corneal Transplantation.
Thank you for taking the time to review our
2011 Annual Report.
If you have any questions regarding the
information inside, or would like to speak with
someone about making a gift or volunteering in
our office, please call us at 317-814-2993.
Do you receive our Focus E-Newsletter?
If you do not, and you would like to be kept up to date on our research,
please email [email protected] to be added to the mailing list.
Interested in volunteering?
No one understands the importance of
better vision more than we do.
9002 N. Meridian St. Suite 212
Indianapolis, IN 46260
Conducting research today
for brighter futures tomorrow.
W W W. C O R N E A . O R G

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