1 HORIZON SCANNING:ORTHOPAEDIC

Transcription

HORIZON SCANNING: ORTHOPAEDIC SURGERY
APRIL 2012
The object of these Horizon Scanning reports is to highlight recently completed and ongoing
clinical trials, research recommendations and new and emerging health technologies. After
feedback from pilot Horizon Scanning exercises and following consultation with the Arthritis
Research UK Orthopaedic Surgery lead, this first Horizon Scanning report only highlights ongoing
clinical trials or those completed since January 2010: follow up reports will also include research
recommendations from clinical guidelines.
Details of all material included in this report are shown in the appendix, sorted according to
anatomical region involved. Further details of each study can be obtained via the links given to the
relevant webpage.
CONTENTS
SEARCH METHODOLOGY
RESULTS
ABBREVIATIONS
APPENDIX: CLINICAL TRIALS
A1 Head …………………………………………………………………………………………
A2 Neck & Cervical Spine ……………………………………………………………….
A3 Spine (Thoracic, Lumbar & Sacral) …………………..……………………….
A3a
Paediatrics
17
A3b
Fracture & Injury
20
A3c
Other
36
A4 Thorax ……………………………………………………………………………………...
A5 Shoulder (including clavicle) ……………..……………………………………..
A5a
Paediatrics
88
A5b
Fracture & Injury
88
A5c
Rotator cuff pathologies
95
A5d
Other
104
A6 Hand & Wrist …………..……………………………………………………………….
A6a
Paediatrics
116
A6b
Fracture & Injury
117
A6c
Other
124
Written by Nadia Corp for: © Arthritis Research UK 2012
1
2
3
4
5
5
7
17
85
88
116
A7
Upper limb (including elbow) ……………………………………………………
A7a
Paediatrics
134
A7b
Fracture & Injury
135
A7c
Other
139
A8 Hip ……….…………………………..……………………………………………………...
A8a
Paediatrics
143
A8b
Fracture & Injury
144
A8c
Arthroplasty
161
A8d
Other
199
A9 Knee ………………………………….………………………………………………………
A9a
Paediatrics
213
A9b
Fracture & Injury
214
A9c
Arthroscopy
214
A9d
Cruciate ligament pathologies
219
A9e
Meniscus/cartilage pathologies
229
A9f
Arthroplasty
235
A9g
Other
288
A10 Foot & Ankle ……….…………………………………………………………………….
A10a
Paediatrics
301
A10b
Fracture & Injury
303
A10c
Arthroplasty
311
A10d
Other
315
A11 Lower Limb…………….……………………………………………………………......
A11a
Paediatrics
324
A11b
Fracture & Injury
327
A11c
Other
337
A12 General ………………….………………………………………………………………...
A12a
Paediatrics
346
A12b
Fracture & Injury
348
A12c
Other
350
134
143
213
301
324
346
SEARCH METHODOLOGY
Clinical Trials Databases Searched
 ClinicalTrials.gov, US
 ISRCTN Register, UK
Keywords searched
Keywords and phrases were used separately or in combination; truncation was used where
possible/applicable.



Orthop[a]edic
Surgery AND bone, spine/spinal, tendon[s], foot/feet, hand[s], joint[s], ligament[s];
Transplant AND bone, cartilage, periosteum;
2
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



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



cementoplasty; vertebroplasty; kyphoplasty;
tenodesis; tenotomy; tendon transfer;
arthroplasty; arthroscopy; arthrodesis;
Bone AND resection, lengthening, graft;
amputation; disarticulation; hemipelvectomy;
discectomy; osteotomy; fasciotomy;
Muscle AND resection, transposition;
Fracture AND fixation, treatment;
anterior cruciate ligament reconstruction;
intervertebral disc chemolysis;
viscosupplementation;
lizarov;
spine/spinal fusion;
traction;
limb salvage;
joint capsule release;
distraction osteogenesis
Date limits
This report includes trials that were completed or ongoing between January 2010 and April 2012.
Age limits
None
RESULTS
A total of 1,630 completed or ongoing clinical trials were identified with orthopaedics: these are
tabulated in the appendix divided into anatomically distinct sections:
 A1: Head (n = 9);
 A2: Neck & Cervical spine (n = 54);
 A3: Spine (Thoracic, Lumbar & Sacral) (n = 416);
 A4: Thorax (n = 15);
 A5: Shoulder (including clavicle) (n = 162);
 A6: Hand & Wrist (n = 115);
 A7: Upper limb (including elbow) (n = 52);
 A8: Hip (n = 436);
 A9: Knee (n = 524);
 A10: Foot & Ankle (n = 140);
 A11: Lower limb (n = 122);
 A12: General (n = 163).
For clarity some sections have been further divided into sub-sections including paediatrics (studies
solely of individuals ≤18 years old), fracture and injury, arthroplasty, specific pathologies or groups
of pathologies, and other. These are further arranged according to type of intervention:
behavioural; device; dietary supplements; drug including biologics; procedure; other and
3
miscellaneous observational studies. (Trials where the end date was not specified are included
based update the last update status e.g. recruitment complete etc, and follow-up time points if
applicable.)
Unless otherwise stated in the table trials involve participants of both genders. Each clinical study
has a weblink which can be followed for further details. Where there was uncertainty regarding
whether a study should be included or not (usually due to its focus), the decision aired on the side
of caution and the trial was included in the feedback.
ABBREVIATIONS
Adult
Child
Comp
CT
CT ID
F-only
Grp
Invite
M-only
n
N/K
NR
RCT
Rec
Recruit
Senior
Susp
Term
Wdrwn
Adult (18-65 years)
Child (birth-17 years)
Completed
Controlled trial
Clinical Trials Identifier
Females only
Group
Enrolling by invitation
Males only
Enrollement
Not known
NR
Randomized controlled trial.
Recruiting
Recruitment
Senior (66+ years)
Suspended
Terminated
Withdrawn
4
FULL TEXT APPENDIX
SECTION B: CLINICAL TRIALS
Clinical trials identity number (CT ID): Prefix of ACTRN denotes Australian New Zealand Clinical Trials Registry; ChiCTR - Chinese Clinical Trial Register; CTRI Clinical Trials Registry, India; DRK – German clinical Trials Register; NCT - National Clinical Trials Identifier; IRCT - Iranian Registry of Clinical Trials; ISRCTN International Standard Randomized Controlled Trial Number; JapicCTI - Japan Pharmaceutical Information Center Clinical Trials; JMA - Japan Medical Association
Center for Clinical Trials Register; KCT - Clinical Research Information Service (CRiS), Republic of Korea; NTR – Nederland Trial Register; PACTR - Pan African
Clinical Trial Registry; RPCEC - Cuban Public Registry of Clinical Trials; SLCTR - Sri Lanka Clinical Trials Registry; UKCRN – UK Clinical Research Network; UMIN –
University Hospital Medical Information Network. Note: Where no end date was given the following were used: completion date for primary outcome measure –
italics; last update – preceeded with a ?; start date + final timepoint of outcomes – preceeded with a >.
A1. HEAD
Title
Phases: trial design (control)
CT ID
Behavioural
Biofeedback-Based Cognitive
Behavioral Treatment for
Temporomandibular Disorders
Phase II/III: RCT, safety/efficacy
study
NCT00769561
Device
Conservative Treatment of
Patients With Temporomandibular
Disorders
RCT, efficacy study
NCT01021306
Interventions
Conditions
Behavioral:
Temporomandibular
Biofeedback-Based Disorders
Cognitive Behavioral
Treatment; Device:
Interocclusal splint
therapy
Recruit
n
Rec
100
Adt Jun-08 Jul-10 Philipps
http://ClinicalTrials.gov/show/NCT00769561
Sen
University
Marburg Medical
Center;
PsychotherapieAmbulanz
Marburg e.V.
80
Adt Jan-10 Apr-12 Palmer College http://ClinicalTrials.gov/show/NCT01021306
Sen
of Chiropractic;
National Center
for
Complementary
and Alternative
Medicine
(NCCAM);
University of
Iowa; Schaeffer
Chiropractic
Device: Chiropractic Temporomandibular Active,
w/Activator & Self
Disorders
NR
Care; Device: Dental
Care & Self Care;
Other: Sham AMCT;
Other: Self-Care
Only Group
5
Age Start
(Grp) Date
End Sponsors
Date
URL
Drugs including biologics
The Use of PET/CT to Evaluate
Synovitis in the
Temporomandibular Joint (TMJ)
Phase II: Non-randomized,
parallel assignment
NCT01471418
Drug: PET/CT with
18-FDG
Temporomandibular
Joint; Conservative
Treatment Therapy
Rec
Procedure
The New Serial Treatment of
Temporomandibular Disorders
RCT
NCT00932594
Procedure: Adjust
Temporomandibular
Rec
the TMJ Pressure to Disorder
Normal Value; Other:
Do not adjust the
pressure of TMJ
Evaluation of Navigation Assisted Procedure:
Zygomatic Fractures Rec
Reconstruction of Posttraumatic
Navigation Surgery;
Zygomatic Deformity
Procedure:
Phase III: RCT, efficacy study
Traditional Surgery
NCT01487018
Hyperbaric Oxygen Treatment of Procedure:
Osteoradionecrosis
Rec
Mandibular Osteoradionecrosis. A Hyperbaric oxygen
Randomized Clinical Study
Phase II: RCT, efficacy study
NCT00760682
A Comparison of Arthrocentesis, Procedure:
Temporomandibular Active,
Arthroscopy and Arthroplasty in
arthrocentesis;
Joint Dysfunction
NR
the Treatment of
Procedure:
Temporomandibular Joint
arthroscopy;
Dysfunction
Procedure:
Non-randomised, parallel
arthroplasty
assignment, efficacy study
NCT00636727
Miscellaneous observational studies
Craniofacial Surgery Perioperative
Registry
Prospective study
NCT00658242
Craniotomy
Rec
20
Adt Dec-11 Oct-12 University of
Sen
Pennsylvania
4
Child Jan-06 Dec-16 Sun Yat-sen
Adt
University
78
Child Dec-11 Jun-15 Peking
Adt
University
114
Adt Jun-08 Apr-11 Rigshospitalet,
Sen
Denmark
100
Adt Jan-07 Feb-10 Emory University http://ClinicalTrials.gov/show/NCT00636727
Sen
600 Child Mar-08 Jun-13 Children's
Adt
Hospital of
Philadelphia;
Children's
Anesthesiology
Associates, Ltd.
6
An Evaluation of Psychological
Parameters That May Influence
the Outcome Following
Arthroscopy and Arthroplasty for
Temporomandibular Joint Surgery
Prospective, cohort study
NCT01396694
Psychological
Predictors
Rec
105
Recruit
n
Rec
250
Adt Jun-09 Dec-11 Emory University http://ClinicalTrials.gov/show/NCT01396694
Sen
A2. NECK AND CERVICAL SPINE
Title
CT ID
Behavioural
Collar Immobilization Following a
Posterior Cervical Laminectomy
and Fusion
RCT, efficacy study
NCT01383876
Device
GRANVIA®-C Cervical Disc
Prosthesis Multicenter Pilot Study
NCT01518582
NuNEC™ disc prosthesis versus
Prestige® artificial cervical disc
replacement: a pilot study
RCT
ISRCTN63878911
Comparison of DISCOVER™
Artificial Cervical Disc and ACDF
for Treatment of Cervical DDD
(IDE Study)
RCT, safety/efficacy study
NCT00432159
Interventions
Conditions
Behavioral: Collar; Cervical Spondylosis
Behavioral: No Collar With Symptomatic
Neurological
Compression
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt Jun-11 Jun-14 Brigham and
Sen
Women's
Hospital;
Massachusetts
General Hospital
Device: Cervical
Cervicobrachial
arthroplasty surgery Neuralgia; Cervical
with Granvia-C
Discopathy
Not yet 100
Rec
NuNEC™ cervical
disc replacement;
Prestige® cervical
disc replacement
Active
60
Child May-10 May-16 North Tees and http://www.controlledAdt
Hartlepool NHS trials.com/ISRCTN63878911
Sen
Foundation Trust
(UK)
Active,
NR
550
Adt Jul-06 Dec-15 DePuy Spine
Sen
Cervical
degenerative disc
disease
Device: Arthroplasty Cervical
(DISCOVER™
Degenerative Disc
Artificial Cervical
Disease
Disc); Device: ACDF
(allograft with SLIM
LOC® Anterior
Cervical Plate
System)
7
Adt Feb-12 Mar-17 Medicrea
International
Study to Investigate the
Performance of Cervical
Arthroplasty for the Treatment of
Cervical Degenerative Disc
Disease
Phase IV: Prospective, cohort
study
NCT00700739
Interbody Fusion Devices in the
Treatment of Cervicobrachial
Syndrome
NCT01511445
Device: Arthroplasty Cervical
(DISCOVER™)
Degenerative Disc
Disease
Term
Device: Anterior
Radiating Pain;
Rec
cervical discectomy Myelopathy;
and fusion (ACDF) Cervicobrachial
with PEEK Cage;
Syndrome
Device: Anterior
cervical discectomy
and fusion (ACDF)
with a Valeo CSC
Cage
Study of Safety & Effectiveness of Device: PRESTIGE® Cervical
Active,
PRESTIGE® LP Cervical Disc vs. LP Cervical Disc;
Degenerative Disc
NR
Anterior Cervical Fusion in
Device: ATLANTIS Disease
Cervical DDD
Anterior Cervical
Phase III: Single group
Plate
assignment, safety/efficacy
study
NCT00667459
Pivotal IDE Study of the
Device: ATLANTIS™ Radiculopathy;
Active,
BRYAN(R) Cervical Disc
Cervical Plate
Myelopathy; Cervical NR
Prosthesis in the Treatment of
System and allograft; Degenerative Disc
DDD Versus ACDF
Device: BRYAN
Disease
Cervical Disc
NCT00437190
Prosthesis
A Clinical Trial Evaluating a Total Device: CerPass® Cervical Disc
Invite
Disc Replacement in Patients With Total Disc
Disease
Cervical Disc Disease
Replacement
NCT01433367
An Assessment of P-15 Bone
Device: P-15
Cervical
Rec
Putty in Anterior Cervical Fusion Synthetic
Degenerative Disc
With Instrumentation
osteoconductive
Disease (DDD)
Phase III: RCT, safety/efficacy
bone substitute;
study
Other: Autologous
NCT00310440
bone
43
Adt May-08 May-15 DePuy
International
100
Adt Dec-11 Dec-14 Amedica
Sen
Corporation
280
Adt Jan-05 Nov-14 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00667459
Sen
and Biologics
494
Adt Jun-03 Oct-14 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00437190
Sen
and Biologics
30
Adt May-10 Dec-13 NuVasive
180
Adt Jan-06 Aug-13 AO Clinical
Sen
Investigation and
Documentation;
CeraPedics, Inc
8
PRESTIGE® Cervical Disc Study
Phase IV: RCT, safety/efficacy
study
NCT00642876
Device: Allograft
Fusion and
ATLANTIS™
Cervical Plate
System; Device:
PRESTIGE®
Cervical Disc
Study of the Safety and
Device: PRESTIGE
Effectiveness of the Artificial
LP device at two
Cervical Disc - Low Profile Device adjacent levels;
at Two Adjacent Levels
Device: Bi-level
fusion with
study
ATLANTIS Cervical
NCT00637156
Plate System
Advent™ Cervical Disc Versus
Device: Cervical
Anterior Cervical Discectomy and Artificial Disc
Fusion(ACDF) for Treatment of
(Advent™ Cervical
One Level Degenerative Disc
Disc); Device: ACDF
Disease (IDE Study)
(Hallmark™ Anterior
Cervical Plate
NCT00637312
System with
corticocancellous
allograft bone)
Clinical Outcomes Study
Device: ACDF
Evaluating the Zero-P PEEK
Single group assignment
NCT00945243
Porous Coated Motion (PCM)
Device: Anterior
Artificial Disc
Cervical Discectomy
and Fusion; Device:
study
Porous Coated
NCT00578812
Motion Artificial Disc
Arthroplasty Versus Fusion in
Device: cervical disc
Anterior Cervical Surgery:
prosthesis with a
Prospective Study of the Impact on mobile insert named
the Adjacent Level
Mobi-C; Procedure:
Phase IV: RCT, efficacy study
arthrodesis - cervical
NCT00554528
disk surgery
Degenerative
Cervical Disc
Disease
Active,
NR
541
Adt Oct-02 Jun-13 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00642876
Sen
and Biologics
Cervical
Degenerative Disc
Disease;
Radiculopathy;
Myelopathy
Active,
NR
397
Adt Jun-06 Mar-13 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00637156
Sen
and Biologics
Cervical
Degenerative Disc
Disease
Term
450
Adt Mar-08 Jul-12 Orthofix Inc.;
Sen
Blackstone
Medical dba
Orthofix Spinal
Implants
Cervical Disc
Disease
Active,
NR
14
Adt Jul-09 Jun-12 Synthes USA
Sen
HQ, Inc.
Radiculopathy;
Myelopathy
Active,
NR
494
Adt Jan-05 Jun-12 NuVasive
Rec
220
Adt May-07 May-12 Centre
Hospitalier
Universitaire de
Nice
Clinical
Radiculopathy;
Myelopathy Due to a
Cervical Disk
Disease
9
Evaluating The Safety and
Device: NeoDisc
Effectiveness of The NeoDisc™
Versus ACDF in Subjects With
Single-Level Cervical Disc Disease
NCT00478088
SECURE®-C Cervical Artificial
Device: SECURE-C
Disc Clinical Study
Cervical Artificial
Disc; Procedure:
study
Anterior Cervical
NCT00882661
Discectomy and
Fusion (ACDF)
Comparison of Foley Balloon With Device: foley balloon
or Without Traction for the Cervical only; Device: foley
Ripening
balloon with weight
Phase III: RCT, safety study;
attached
NCT01063244
Study on cervical resorbable
interbody cages
RCT
ISRCTN57772706
Cervical Disc
Degenerative
Disorder
Active,
NR
488
Adt Sep-06 Mar-12 NuVasive
Symptomatic
Cervical Disc
Disease
Active,
NR
380
Adt
Cervical Ripening
Solis (non-resorbable Degenerative disc
PEEK) interbody
disease of the
cage device (no
cervical spine
internal fixation);
Solis RS
(bioresorbable PLLA)
interbody cage
device (no internal
fixation)
Pilot Study to Assess the Efficacy Device: Lubo cervical Elective Surgical
and Safety of the Lubo Cervical
collar
Procedure
Collar
Phase I: Single group
assignment, safety study
NCT00355173
Prospective International
Stand-alone
Cervical
multicentre Evaluation of
polyetheretherketone degenerative disc
Radiological and Clinical Effects of (PEEK) intervertebral disease
stand-alone polyetheretherketone spacers
(PEEK) intervertebral spacers for
anterior cervical discectomy and
fusion (ACDF)
Observational study
ISRCTN42774128
Rec
Comp
Jul-05 Mar-12 Globus Medical
Inc
Adt Jan-09 Jan-11 St. Luke's
Hospital,
FPennsylvania; St
only
Luke's Hopsital
OB/Residency
program
113 Adt Aug-07 Dec-10 Stryker SA
http://www.controlledSen
(Switzerland)
trials.com/ISRCTN57772706
70
Comp
50
Adt May-06 Nov-10 Hadassah
Medical
Organization
Comp
200
Adt Sep-06 Jan-10 Deutsche
Sen
Arthrose Hilfe
e.V. (Germany)
http://www.controlledtrials.com/ISRCTN42774128
10
Efficacy of Riluzole in Surgical
Treatment for Cervical Spondylotic
Myelopathy (CSM-Protect)
NCT01257828
Study Comparing Short Term
Efficacy of Dysport® and Dysport
RU® to Placebo, and to Assess
Efficacy and Safety of Dysport
RU® of Subjects With Cervical
Dystonia
NCT01261611
PureGen: A Radiographic Analysis
of Rate and Quality of Fusion in
Patients Undergoing Anterior
Cervical Discectomy and Fusion
(ACDF)
NCT01291134
Safety and Efficacy of Cethrin® in
Adult Subjects With Acute Cervical
Spinal Cord Injury
Phase II: RCT, safety/efficacy
study
NCT00610337
Procedure
Anterior Vs Posterior Procedures
for Cervical Spondylotic
Myelopathy: Prospective
Randomized Clinical Trial
NCT00876603
Drug: riluzole; Drug: Cervical Spondylotic
Placebo medication Myelopathy
Rec
270
Adt Dec-11 Jul-13 SpineNet
Sen
Drug: Botulinum type Cervical Dystonia
A toxin (Dysport
RU®); Drug:
Botulinum type A
toxin (Dysport®);
Drug: Placebo
Rec
350
Adt Apr-11 Mar-13 Ipsen
Sen
Biological: PureGen Cervical
Osteoprogenitor Cell Degenerative Disc
Allograft
Disease
Rec
50
Adt Feb-11 Oct-11 Alphatec Spine,
Sen
Inc.
Drug: Cethrin® (BA- Acute Cervical
210); Procedure:
Spinal Cord Injury
placebo
Term
200
Adt
Procedure: ACDF; Cervical Spondylotic
Procedure: Cervical Myelopathy
laminoplasty
Rec
100
Adt May-01 Dec-20 The University of http://ClinicalTrials.gov/show/NCT00876603
Sen
Hong Kong
11
Feb-10 Alseres
Pharmaceuticals,
Inc
Treatment of Cervical
Radiculopathy With Arthroplasty
Compared With Discectomy With
Fusion and Cage (ACDF)
RCT, efficacy study
NCT00735176
Procedure: Cervical Radiculopathy,
arthroplasty;
Cervical
Procedure: Anterior
cervical discectomy
and fusion (ACDF)
Conservative or Operative
Procedure: Bouquet Fractures of the
Treatment of Fractures in the Neck pinning of the 5th
Neck
of the 5th Metacarpal Bone
metacarpal bone
RCT, efficacy study
NCT01139528
Safety and Efficacy Study of
NeoFuse in Subjects Undergoing
Multi-Level Anterior Cervical
Discectomy and Fusion
study
NCT01106417
Safety and Preliminary Efficacy
Study of NeoFuse in Subjects
Undergoing Multi-Level Anterior
Cervical Discectomy
study
NCT01097486
Improvement of Trans-operatory
X-ray Visualization During Anterior
Cervical Surgery
Single group assignment,
safety/efficacy study
NCT01342575
Procedure: Anterior Cervical
Cervical Discectomy Degenerative Disc
and Fusion with
Disease;
NeoFuse; Procedure: Degenerative
Anterior Cervical
Spondylolisthesis;
Discectomy and
Spinal Stenosis
Fusion with Granules
Procedure: Anterior Cervical
Cervical Discectomy Degenerative Disc
and Fusion with
Disease;
NeoFuse; Procedure: Degenerative
Anterior Cervical
Spondylolisthesis;
Discectomy and
Spinal Stenosis
Fusion with Allograft
Procedure: IntraVisualization During
operative exposure Cervical Spine
maneuvers
Surgery
Rec
146
Rec
120
Active,
NR
12
Rec
24
Adt Jun-10 Dec-12 Mesoblast, Ltd.
Sen
Rec
50
Adt Dec-10 Apr-12 American British http://ClinicalTrials.gov/show/NCT01342575
Sen
Cowdray Medical
Center
12
Adt Sep-08 Sep-18 Norwegian
University of
Science and
Technology;
Rikshospitalet
University
Hospital;
Haukeland
University
Hospital; Ullevaal
University
Hospital;
University
Hospital of North
Norway; St.
Olavs Hospital
Adt May-10 Dec-13 Oslo University http://ClinicalTrials.gov/show/NCT01139528
Sen
Hospital;
University
Hospital,
Akershus; Asker
& Baerum
Hospital
Adt Jun-10 Jun-13 Mesoblast, Ltd. http://ClinicalTrials.gov/show/NCT01106417
Sen
Surgical Treatment of Cervical
Spondylotic Myelopathy
Phase IV: Single group
NCT00565734
Comparing Surgical to
Conservative Management in the
Treatment of Type II Odontoid
Fractures Among the Elderly
study
NCT00283998
Reducing Dysphagia Associated
With Anterior Cervical Spine
Surgery by Maintaining Low
Endotracheal Tube Cuff Pressure
RCT, efficacy study
NCT00332683
Procedure: standard Cervical Spondylotic Active,
surgical care for
Myelopathy
NR
CSM treatment
375
Procedure: surgical Odontoid Fractures
versus conservative Type II
treatment
166
Rec
Procedure:
Deglutition Disorders Rec
Maintaining low
(15mmHg) ETT cuff
pressure; Procedure:
Maintaining a normal
pressure in the ETT
cuff
Cervical Restorations Placed
Procedure: Relative Non-carious Cervical Active,
Under Two Isolation Methods
isolation with cotton Lesions
NR
Phase II/III: RCT, efficacy study rolls; Procedure:
NCT01506830
Absolute isolation
with rubber dam
Treatment of Type II Odontoid
Procedure: surgical; Neck Injuries; Spinal Comp
Fractures Among the Elderly
Procedure:
Injuries
conservative
treatment
study
NCT00266929
The CSM Trial: A Multicenter
Procedure: Ventral Cervical Spondylotic Active,
Study Comparing Ventral to Dorsal Surgical
Myelopathy
NR
Surgery for Cervical Spondylotic Decompression with
Myelopathy
Instrumented Fusion;
Phase III: Non-randomized,
Procedure: Dorsal
parallel assignment,
Decompression With
or Without Fusion
NCT00506558
Adt Nov-07 Apr-12 AO Clinical
Sen
Investigation and
Documentation;
AOSpine
International
Adt Jan-06 Mar-12 AO Clinical
Sen
Investigation and
Documentation;
AOSpine North
America
40
Adt Sep-06 Dec-11 Lawson Health
Research
Institute
30
Adt Jul-09 Jul-11 Federal
Sen
University of
Pelotas
166
Adt Dec-05 Mar-11 AO Clinical
Sen
Investigation and
Documentation;
AOSpine North
America
100
Adt Nov-06 Feb-11 Greenwich
Sen
Hospital; Yale
University
13
A Clinical Trial Evaluating a Total Cervical spinal
Disc Replacement in Patients with reconstruction
Cervical Disc Disease
Non-randomized (historical),
efficacy study
ISRCTN83445469
Safety Study of Preservon-Treated Procedure: Anterior
Bone Implants for Cervical Fusion Cervical Discectomy
in the Treatment of Cervical
and Fusion
Radiculopathy or Myelopathy
NCT00344890
Laminectomy without or with
Laminectomy;
dorsal Fusion for cervical
laminectomy and
myeloradiculopathy: a randomised fusion.
trial
RCT
ISRCTN72800446
Other
Outcome of Physiotherapy After
Surgery for Cervical Disc Disease:
a Prospective Multi-Centre Trial
RCT, efficacy study
NCT01547611
Shi-style Cervical Manipulations
for Cervical Radiculopathy
NCT01500967
Degenerative Disc
Disease
Cervical
Radiculopathy;
Myelopathy
Comp
30
Adt May-10 Dec-10 Nuvasive Inc.
Sen
(USA)
Rec
120
Adt Sep-06 Dec-10 LifeNet Health
60
Adt Jan-07 Jan-10 Radboud
Sen
University
Nijmegen (The
Netherlands)
Adt Jan-09 Dec-17 Linkoeping
Sen
University;
University
Hospital,
Linkoeping;
Karolinska
University
Hospital; Ryhov
County Hospital;
Lund University
Hospital
Adt Dec-11 May-14 Shanghai
University of
Traditional
Chinese
Medicine; Tianjin
University of
Traditional
Chinese Medicine
Cervical myelopathy Comp
due to cervical spinal
stenosis
Other: Customary
Radiculopathy
treatment; Other:
Structured
behavioural medicine
program
Rec
200
Other: Shi-style
Cervical
cervical
Radiculopathy
manipulations; Other:
Cervical Traction
control
Rec
648
14
Comparison of Outcomes Between Other: early physical
Early Physical Therapy
therapy intervention;
Intervention and Usual Care
Other: usual care
Following Anterior Cervical Fusion
Surgery
RCT, efficacy study
NCT01519115
The Value of Traction in the
Other: Physical
Treatment of Cervical
therapy
Radiculopathy
rehabilitation; Other:
Phase III: RCT
Physical therapy
NCT00979108
Physical therapy
rehabilitation
Effectiveness of Manual Therapy
in Patients With Neck Pain.
RCT, efficacy study
NCT00713843
Other: Manual
Therapy Utrecht;
Other: Physical
Therapy
Effects of Gua Sha and
Other: Gua Sha;
Thermotherapy on Chronic Neck Device:
Pain
Thermotherapy
RCT
NCT01233180
Safety Study of Preservon-Treated Procedure: Anterior
Bone Implants for Cervical Fusion Cervical Discectomy
in the Treatment of Cervical
and Fusion
Radiculopathy or Myelopathy
NCT00344890
Evaluation of the Nursing C-Spine Other: Clinical
(Phase IV)
decision rule Phase IV: Single group
clearing the c-spine
assignment
NCT01353352
Cervical Spine
Degenerative Disc
Disease; Fusion of
Spine, Cervical
Region
Not yet
Rec
40
Radiculopathy; Neck Rec
Pain; Spinal
Diseases;
Musculoskeletal
Diseases;
Neuromuscular
Diseases;
Intervertebral Disk
Displacement
Neck Pain
Active,
NR
192
Neck Pain
Comp
50
Rec
120
Cervical
Radiculopathy;
Myelopathy
Fracture of Cervical
Spine; Fracture
Dislocation of
Cervical Spine
180
Adt Jan-12 Dec-12 Texas Woman's http://ClinicalTrials.gov/show/NCT01519115
Sen
University; Texas
Society of Allied
Health
Professions;
Texas Spine and
Joint Hospital
Adt Jul-09 Jul-12 Intermountain
Sen
Health Care, Inc.;
University of
Utah; Wilford Hall
Medical Center;
Empi, A DJO
Company
Adt Sep-08 Feb-12 Radboud
Sen
University;
Stichting
Garantiefonds
Spaarneland, The
Netherlands
Adt Sep-10 Feb-11 Universität
Sen
Duisburg-Essen
Adt Sep-06 Dec-10 LifeNet Health
Comp 3633 Child Jan-08 Aug-10 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01353352
Adt
Research
Sen
Institute;
Canadian
Institutes of
Health Research
15
MaxAn Post Market Surveillance
Validation
Prospective, case-only study
NCT01343693
Comparing Outcomes of Elbow
Extension Tendon Transfers
Retrospective, cohort study
NCT01204736
Comparison of Cage Versus Plate
in One Level Cervical Disc
Disease
NCT01011569
PRESTIGE Observational Study
Prospective study
NCT00875810
Trinity Evolution in Anterior
Cervical Disectomy and Fusion
(ACDF)
NCT00951938
DDD; Deformity;
Tumor; Fracture
Rec
200
Adt Jun-11 Feb-15 Biomet, Inc.
Sen
Cervical Spinal Cord
Injury
Rec
45
Cervical Disc
Disease
Rec
80
Adt Aug-11 Sep-14 Department of
Veterans Affairs;
Rehabilitation
Institute of
Chicago;
Northwestern
University; Case
Western Reserve
University; Loyola
University
Adt Apr-04 Mar-13 Seoul National
Sen
University
Hospital
Active,
NR
225
Adt Apr-08 Jan-13 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00875810
Sen
& Biologics ECA
Active,
NR
200
Adt Aug-09 Apr-12 Orthofix Inc.
Sen
Degenerative
Cervical Disc
Disease
Degenerative Disc
Disease
16
A3. SPINE (Thoracic, Lumbar & Sacral)
A3A: PAEDIATRICS
Title
CT ID
Behavioural
Study of the Effects of Hypnosis
Before Undergoing Surgery, on
Anxiety in Children Aged 10 to 18
Years
RCT, efficacy study
NCT01320956
Device
Bracing in Adolescent Idiopathic
Scoliosis Trial (BrAIST)
Phase III: RCT
NCT00448448
Dietary supplements
Growth Hormone Therapy and
Bone Quality in Pediatric
Osteoporosis
NCT00757393
Interventions
Conditions
Behavioral: Pre
Osteotomy and
operative nurse
Spinal Column
consultation and
Surgery
Hypnosis; Other: Pre
operative nurse
consultation
Device: Brace;
Other: Watchful
waiting
Adolescent
Idiopathic Scoliosis
Dietary Supplement: Osteoporosis
Vitamin D + Calcium
+ Exercise program;
Drug: Vitamin D +
Calcium + Exercise
program +
Humatrope
Recruit
Rec
n
Age Start
(Grp) Date
End Sponsors
Date
120 Child Mar-11 Sep-13 Assistance
Publique Hôpitaux de
Paris
URL
Active,
NR
500 Child Feb-07 Aug-12 University of
Iowa; National
Institute of
Arthritis and
Musculoskeletal
and Skin
Diseases;
Canadian
Institutes of
Health
Research;
Shriners
Hospitals for
Children;
Children's Mercy
Hospital Kansas
City; University
of Rochester
Not yet
Rec
28
17
Child Sep-08 Jan-12 The Hospital for http://ClinicalTrials.gov/show/NCT00757393
Sick Children
Autologous Stem Cells for Spinal
Cord Injury (SCI) in Children
study
NCT01328860
Non-Idiopathic Scoliosis Treated
With Tranexamic Acid
NCT01089140
Biological: bone
marrow progenitor
cells (BMPC)
autologous
transplantation
Spinal Cord Injury
Drug: Tranexamic
Non-idiopathic
acid 10mg/kg/hr;
Scoliosis
Drug: Tranexamic
acid 100 mg/kg/h
infusion; Drug: Saline
solution
An Efficacy and Safety Trial of
Drug: Zoledronic
Osteoporosis
Intravenous Zoledronic Acid Twice acid; Drug: Placebo
Yearly in Osteoporotic Children
Treated With Glucocorticoids for
Chronic Inflammatory Conditions
study
NCT00799266
The Use of Intraoperative
Drug: DepoDur™
Pain Management;
Intrathecal Morphine Versus
Spinal Fusion;
Epidural Extended Release
Scoliosis
Morphine for Postoperative Pain
Control in Pediatric Patients
Undergoing Posterior Spinal
Fusion
study
NCT00880607
Rec
Rec
10
Child Apr-11 Oct-14 Memorial
Hermann
Healthcare
System; Institute
for Rehabilitaion
and Research
Foundation; The
University of
Texas; Anderson
Cancer Center;
Baylor College
of Medicine;
Methodist
Hospital System
Research
Institute,
Houston
120 Child Nov-09 Nov-12 The Hospital for http://ClinicalTrials.gov/show/NCT01089140
Sick Children
Rec
92
Child Dec-08 Oct-12 Novartis
Rec
80
Child Dec-08 Dec-11 Children's
Hospital
Colorad;
University of
Colorado,
Denver
18
Peri-operative pain management in Epidural infusion of Post-operative pain
children and adolescents
bupivacine,
after scoliosis
undergoing scoliosis surgery: pain, epinephrine and
surgery
nausea and psychological impact fentanyl + patient
RCT, efficacy study
controlled extra
ISRCTN12885779
boluses; intravenous
infusion of (S)ketaminehydrochlorid
Alendronate in Juvenile
Drug: Alendronate
Juvenile
Osteoporosis
(Fosamax)
Osteoporosis; Low
NCT00920075
Bone Density;
Fractures
Other
Prospective Study of Scoliosis in
Children With Cerebral Palsy
Prospective, case control study
NCT00680264
Dexmedetomidine on
Intraoperative Somatosensory and
Motor Evoked Potential Monitoring
During Neurosurgery in Pediatric
Patients
Single group assignment, safety
study
NCT01512147
Effect of High-Calcium Milk and
Weight-Bearing Exercise on Bone
Mineral Status of Pre-Pubertal
Girls
RCT
NCT00979511
Comp
38
Child Apr-09 Apr-11 University
http://www.controlledHospital of
Nothern Sweden
(Sweden)
Comp
11
Child Jul-09 Oct-10 Medical
Adt
University of
South Carolina;
FDA Office of
Orphan Products
Development;
Merck
Cerebral Palsy;
Scoliosis
Rec
Other: Isoflurane,
Propofol,
Dexmedetomidine
Tethered Spinal
Cord; Brain Tumor;
Cranio Cervical
Compression
Rec
Other: milk and
exercise
Osteoporosis
Shilla Growth Permitting Spinal
Instrumentation System for
Treatment of Scoliosis in the
Immature Spine
Prospective study
NCT00577226
Scoliosis
Active,
NR
Term
402 Child Jun-08 Dec-15 Harms Study
Adt
Group
Foundation;
DePuy Spine
20 Child Dec-11 Dec-12 Oregon Health
and Science
University
120 Child Feb-09 Dec-10 Nutrition Center http://ClinicalTrials.gov/show/NCT00979511
of the
FPhilippines;
only
Nestlé
Foundation
50
19
Child Apr-05 Apr-15 Arkansas
Children's
Hospital
Research
Institute
Study of the Surgical Treatment of
Early Onset Scoliosis Using a Noninvasive Growing Rod
NCT01362881
Risk Factors for Psychiatric
Disorders Associated With
Adolescent Idiopathic Scoliosis
NCT00958373
Scoliosis
Rec
50
Child Jan-12 Jan-15 Surgi C Limited http://ClinicalTrials.gov/show/NCT01362881
Adolescent
Term
0
Child Oct-06 Mar-11 University of
British Columbia
Recruit
n
Age Start
(Grp) Date
Rec
150
Adt Apr-11 Dec-14 Department of http://ClinicalTrials.gov/show/NCT01093014
Sen
Veterans Affairs;
University of
Iowa
Rec
160
Adt Sep-09 Jan-13 University of
Sen
Washington
Rec
72
Adt Aug-10 Dec-12 University of
British Columbia;
Canadian
Institutes of
Health Research
A3B: FRACTURE & INJURY
Title
CT ID
Behavioural
Novel Intervention to Influence
Muscle Plasticity in Veterans
efficacy study
NCT01093014
Telephone Intervention for Pain
Study (TIPS)
RCT, efficacy study
NCT00663663
Interventions
Conditions
Behavioral: Active
Resisted Standing
Spinal Cord Injuries
Behavioral:
Chronic Pain;
Telephone-Delivered Multiple Sclerosis;
Intervention 1;
Amputation; Spinal
Behavioral:
Cord Injury
Telephone-Delivered
Intervention 2
Spinal Cord Injury Energy
Behavioral: Energy Spinal Cord Injury
Management Program
Management
Phase II/III: RCT, efficacy study Program; Behavioral:
NCT01184365
Energy Management
Program
20
End Sponsors
Date
URL
Addressing Vertebral Osteoporosis Behavioral:
Osteoporosis
Incidentally Detected to Prevent
Reminders and
Future Fractures
opinion leader
Non-randomized, parallel
generated guidelines
+/- leaflets and
study
counselling; Other:
NCT00388908
Usual Care
Active,
NR
240
Adt Nov-06 May-11 University of
Sen
Alberta;
Canadian
Institutes of
Health Research
Spinal Cord Injuries;
Stroke; Paralysis;
Tetraplegia;
Paraplegia
Rec
25
Device: Lokomat
treadmill training;
Other: Aquatic
exercise therapy
Spinal Cord Injury
Rec
36
Device: Vertebral
Augmentation
(STABILIT); Other:
Non-operative
Management
Painful Osteoporotic
Vertebral
Compression
Fractures (VCF)
Rec
130
Adt May-05 Jun-15 Case Western http://ClinicalTrials.gov/show/NCT00623389
Sen
Reserve
University;
National
Institutes of
Health;
Department of
Veterans Affairs
Adt Apr-11 Dec-14 University of
Maryland;
Shepherd
Center, Virginia
C. Crawford
Research
Institute
Adt Nov-11 Nov-14 DFINE Inc.
Sen
Device: Vertebral
Augmentation
(STABILIT); Other:
Non-operative
Management
Painful Osteoporotic
Vertebral
Compression
Fractures (VCF)
Rec
130
Adt Nov-11 Nov-14 DFINE Inc.
Sen
Rec
10
Adt
Sen
Device
Evaluation of an Advanced Lower Device: IST-16 (16Extremity Neuroprostheses
channel implanted
stimulator-telemeter)
NCT00623389
Comparison of Lokomat and
Aquatic Exercise for Individuals
With Chronic Incomplete Spinal
Cord Injury
Phase I: RCT, safety/efficacy
study
NCT01407354
The PRIORi-T Trial--Prospective
Randomized Investigation of
Radiofrequency Targeted
Vertebral Augmentation
NCT01480167
The PRIORi-T Trial--Prospective
Randomized Investigation of
Radiofrequency Targeted
Vertebral Augmentation
NCT01480167
A Neuroprosthesis for Seated
Posture and Balance
study
NCT01474148
Device: IRS-8 (8Spinal Cord Injury;
Channel implanted Paralysis;
stimulator-telemeter) Tetraplegia;
Paraplegia
21
Jul-11 Jan-14 Case Western http://ClinicalTrials.gov/show/NCT01474148
Reserve
University;
Department of
Veterans Affairs
Evaluation of safety and
Osseofix Spinal
effectiveness of the Osseofix
Fracture Reduction
Spinal Fracture Reduction System System
in treating spinal compression
fractures
ISRCTN26909676
OsseoFix™ Spinal Fracture
Device: OsseoFix
Reduction System in Treating
Spinal Fracture
Spinal Compression Fracture
Reduction System
Phase II/III: Non-randomized,
NCT00961714
Comparison of Balloon
Device: balloon
Kyphoplasty and Vertebroplasty in kyphoplasty;
Subacute Osteoporotic Vertebral Procedure:
Fractures
vertebroplasty
study
NCT00749086
Device: balloon
Kyphoplasty and Vertebroplasty in kyphoplasty;
Subacute Osteoporotic Vertebral Procedure:
Fractures
vertebroplasty
study
NCT00749086
Clinical Evaluation of the
Device: Crosstrees
Crosstrees Pod™ in the Treatment Pod system for PVA
of Pathologic Fracture of the
Vertebral Body (Levels T4 - L5) in
Adult Patients
NCT00933036
Vertebral fractures
Active
150
Adt Nov-11 Nov-13 Alphatec Spine
Sen
(UK)
Vertebral
Compression
Fractures
Rec
125
Adt Aug-09 Jul-13 Alphatec Spine, http://ClinicalTrials.gov/show/NCT00961714
Sen
Inc.
Osteoporotic
Vertebral Fracture;
Between T5 and L5;
Chronic Arthritis,
Longer Than Six
Weeks Duration
Rec
200
Adt Dec-07 Dec-12 Assistance
Sen
Paris; Ministry of
Health, France
Osteoporotic
Vertebral Fracture;
Between T5 and L5;
Chronic Arthritis,
Longer Than Six
Weeks Duration
Rec
200
Sen
Paris; Ministry of
Health, France
Pathologic Fracture
of the Vertebra Due
to Osteoporosis
Rec
118
Adt Jun-09 Dec-12 Crosstrees
Sen
Medical Inc.
22
http://www.controlledtrials.com/ISRCTN26909676/
Clinical Evaluation of the
Device: Crosstrees
Crosstrees Pod™ in the Treatment Pod system for PVA
of Pathologic Fracture of the
Vertebral Body (Levels T4 - L5) in
Adult Patients
NCT00933036
The Kiva® System as a Vertebral Device: Vertebral
Augmentation Treatment
augmentation
study
NCT01123512
DuraGen Plus® Adhesion Barrier Device: DuraGen
for Use in Spinal Surgery
Plus Adhesion
Barrier Matrix
NCT00387829
Influence of Bone Strength
Device: DensiProbe
Measured by DensiProbe on Bone Hip
Related Fixation Failure
NCT00822159
Unipedicular vs. Bipedicular
Device: Kyphon®
Kyphoplasty for the Treatment of Balloon Kyphoplasty
Osteoporotic Vertebral Fractures (Kyphon Inc;
Phase IV: RCT, safety/efficacy Sunnydale, CA)
study
NCT01383616
Unipedicular vs. Bipedicular
Device: Kyphon®
Kyphoplasty for the Treatment of Balloon Kyphoplasty
Osteoporotic Vertebral Fractures (Kyphon Inc;
Phase IV: RCT, safety/efficacy Sunnydale, CA)
study
NCT01383616
Monopolar Electrosurgery Versus Device: ultrasound
Ultrasound Scissors in
scissors - Harmonic
Thoracoscopic Ventral
ACE; Device:
Spondylodesis
electroscalpel (Erbe
Phase IV: RCT, safety/efficacy Vio 300; Aesculap
study
AG)
NCT00941213
Pathologic Fracture
of the Vertebra Due
to Osteoporosis
Rec
118
Adt Jun-09 Dec-12 Crosstrees
Sen
Medical Inc.
Spinal Fractures;
Fractures,
Compression; Back
Injuries
Rec
425
Adt
Sen
Jul-10 Aug-12 Benvenue
Medical, Inc.
Spinal Injuries;
Adhesions
Term
500
Adt Oct-06 Dec-11 Integra
Sen
LifeSciences
Corporation
Femoral Fractures;
Hip Fractures;
Osteoporosis; Bone
Density
Term
198
Adt Nov-08 Sep-11 AO Clinical
Sen
Investigation and
Documentation
Vertebral
Compression
Fracture
Active,
NR
45
Adt
Sen
Jul-06 Sep-11 Hospital for
Special Surgery,
New York
Vertebral
Compression
Fracture
Active,
NR
45
Adt
Sen
Jul-06 Sep-11 Hospital for
Special Surgery,
New York
Rec
40
Adt Dec-09 Aug-11 University of
Sen
Cologne;
Ethicon EndoSurgery
(Europe) GmbH
Fractures of
Vertebral Bodies
23
Cardiovascular Fitness for
Robotically Assisted Treadmill
Training in Persons With Chronic
Incomplete Spinal Cord Injury
RCT, efficacy study
NCT00385918
Device: Lokomat
Training; Other:
Home stretching
protocol
Feasibility Study of Balloon
Device: balloon
Kyphoplasty in Traumatic Vertebral kyphoplasty
Fractures Needing Surgical
Fixation
assignement, safety/efficacy
study
NCT00749229
Treatment of Malignant Vertebral Device: balloon
Fractures With Percutaneous
kyphoplasty
Balloon Kyphoplasty.
NCT00748631
Medtronic SCORE Study - Study Device: Kyphon®
of Curette Use for Obtaining
Curette
Restoration of Vertebral Body
Anatomy in Balloon Kyphoplasty
study
NCT00810043
Medico-Economical Impact of the Device: Brindley
Brindley Neurosurgical Technique technique (bladder
in France
system)
study
NCT00221767
The Effect of AposTherapy on the Device:
Level of Pain, Function and Quality AposTherapy
of Life in Patients With Neuromuscular and Neurological
Disorders
NCT01266382
Paraplegia;
Quadriplegia; Spinal
Cord Injury;
Tetraplegia
Comp
40
One or Two
Traumatic Vertebral
Fractures; Located
Between T11 and
L5,; Balloon
Kyphoplasty
Term
17
Vertebral Fracture;
Multiple Myeloma;
Osteolytic
Metastases
Term
60
Adt Oct-07 Nov-10 Assistance
Sen
Paris
Vertebral Body
Compression
Fractures (VCFs)
Comp
120
Adt Feb-09 Oct-10 Medtronic Spine http://ClinicalTrials.gov/show/NCT00810043
Sen
LLC
Spinal Cord Injuries; Active,
Neurogenic Bladder
NR
Disorder;
Paraplegia;
Quadriplegia
53
Adt Jun-05 Apr-10 University
Sen
Hospital,
Bordeaux;
Ministry of
Health, France
Osteoarthritis; Spinal
Diseases; Ligament
Rupture; Lower
Extremity Fracture;
Neurological
Disorders
N/K
Adt
Sen
Rec
24
Adt Oct-06 Jun-11 Department of http://ClinicalTrials.gov/show/NCT00385918
Sen
Veterans Affairs;
University of
Maryland;
Kernan
Orthopaedics &
Rehabilitation
Hospital
Adt Dec-07 Mar-11 Assistance
Sen
Paris; Ministry of
Health, France
N/K
Jul-09 Assaf-Harofeh http://ClinicalTrials.gov/show/NCT01266382
Medical Center;
Apos Medical
and Sports
Technology Ltd.
Dietary supplements
Analgesic Effects of the Gastrolith, Dietary Supplement: Osteoporosis
in Osteoporotic Patients Suffering Gastrolith; Other:
From Recent Skeletal Pain
Placebo
Caused by Vertebral Fractures
study
NCT01482858
Comparison of the Effect of an
Ongoing Treatment With
Alendronate or a Drug Holiday on
the Fracture Risk in Osteoporotic
Patients With Bisphosphonate
Long Term Therapy
study
NCT01512446
Mesenchymal Stem Cells
Transplantation to Patients With
Spinal Cord Injury
Phase I/II: Single group
study
NCT01446640
Safety Study of GRNOPC1 in
Spinal Cord Injury
NCT01217008
Denosumab Fracture Intervention
Randomized Placebo Controlled
Trial in Japanese Patients With
Osteoporosis
study
NCT00680953
Not yet
Rec
80
Drug: Alendronate;
Drug: Placebo
Osteoporosis
Biological: bone
marrow derived
mesenchymal stem
cells
Spinal Cord Injury
Rec
20
Biological:
GRNOPC1
Spinal Cord Injury
Active,
NR
10
Drug: Denosumab; Osteoporosis
Drug: Placebo; Drug:
Alendronate sodium
hydrate
Adt Dec-11 Aug-12 Amorphical Ltd. http://ClinicalTrials.gov/show/NCT01482858
Sen
Not yet 7000 Adt Jan-12 Mar-15 Evangelisches http://ClinicalTrials.gov/show/NCT01512446
Rec
Sen
Krankenhaus
Lutherhaus
gGmbH;
German Federal
Ministry of
Education and
Research
Child Oct-11 Jun-14 Guangzhou
Adt
General Hospital
of Guangzhou
Military
Command
Adt
Oct-10 Oct-12 Geron
Corporation
Active, 1100 Adt May-08 Sep-12 Daiichi Sankyo
NR
Sen
Co., Ltd.
25
Impact of Pre-surgical Nasal
Bacterial Reduction on
Postoperative Surgical Site
Infections
assignment
NCT01148030
An Open-Label Long-Term Study
Of Pregabalin For The Treatment
Of Central Neuropathic Pain
study
NCT01202227
Single Injection of
REGN475/SAR164877 in
Treatment of Vertebral Fracture
Pain
NCT01001715
Minocycline and Perfusion
Pressure Augmentation in Acute
Spinal Cord Injury
Phase I/II: RCT, safety/efficacy
study
NCT00559494
Drug: 3M Skin and
Nasal Antiseptic
Surgical Site
Infection; displaced
hip fractures; spinal
instability/fractures
Drug: pregabalin
Spinal Cord
Diseases; Spinal
Cord Injuries;
Neuralgia; Pain
Do Aromatase Inhibitors (AIs)
Decrease Intestinal Calcium
Absorption?
NCT00766532
Rec
400 Child Jun-10 Jul-12 3M
Adt
Sen
Active,
NR
100
Adt Sep-10 Mar-12 Pfizer
Sen
Drug:
Back Pain
REGN475/SAR1648
77; Drug: Placebo
Term
41
Adt Nov-09 Jan-11 Sanofi-Aventis; http://ClinicalTrials.gov/show/NCT01001715
Sen
Regeneron
Pharmaceuticals
Drug: Minocycline;
Drug: placebo;
Procedure: SCPP
augmentation;
Procedure: SCPP
control
Rec
60
Drug: Aromatase
Inhibitor
Breast Cancer;
Osteoporosis;
Osteopenia;
Fracture; Fall
Comp
11
Child Jun-04 Nov-10 University of
Adt
Calgary;
Sen
Paralyzed
Veterans of
America;
American
Association of
Neurological
Surgeons;
Hotchkiss Brain
Institute,
University of
Calgary
Child Jan-09 Oct-10 University of
Adt
Wisconsin,
Sen
Madison
Fonly
26
Efficacy in Reducing Fractures and Drug: Zoledronic acid Male Osteoporosis
Safety of Zoledronic Acid in Men 5 mg iv; Drug:
With Osteoporosis
Placebo
study
NCT00439647
The Effect of PTH(1-84) or
Drug: Parathyroid
Back Pain
Alendronate on Reduction of Back hormone (PTH) (1Pain in Postmenopausal Women 84); Drug:
With an Osteoporosis Related
Alendronate
Vertebral Fracture(s) (FP-005-IM)
study
NCT00713258
The Effect of PTH(1-84) or
Drug: Parathyroid
Back Pain
Alendronate on Reduction of Back hormone (PTH) (1Pain in Postmenopausal Women 84); Drug:
With an Osteoporosis Related
Alendronate
Vertebral Fracture(s) (FP-005-IM)
study
NCT00713258
Effect of Teriparatide Compared to Drug: teriparatide;
Osteoporosis,
Risedronate on Back Pain in
Drug: risedronate;
Postmenopausal;
Women With a Spine Fracture
Drug: placebo; Drug: Back Pain; Spinal
Caused by Osteoporosis
placebo
Fracture
NCT00343252
Effect of Teriparatide Compared to Drug: teriparatide;
Osteoporosis,
Risedronate on Back Pain in
Drug: risedronate;
Postmenopausal;
Women With a Spine Fracture
Drug: placebo; Drug: Back Pain; Spinal
Caused by Osteoporosis
placebo
Fracture
NCT00343252
Procedure
Comparing Surgical
Decompression Versus
Conservative Treatment in
Incomplete Spinal Cord Injury
RCT, efficacy study
NCT01367405
Procedure: Surgical Central Spinal Cord
decompression;
Syndrome
Procedure:
Conservative
treatment
Comp 1199 Adt Dec-06 Oct-10 Novartis
Sen
Pharmaceuticals
Term
75
Adt Apr-08 Sep-10 Nycomed
Sen
Fonly
Term
75
Adt Apr-08 Sep-10 Nycomed
Sen
Fonly
Comp
712
Adt Jun-06 Jun-10 Eli Lilly and
Sen
Company
Fonly
Comp
712
Adt Jun-06 Jun-10 Eli Lilly and
Sen
Company
Fonly
Not yet
Rec
72
27
Adt Jan-12 Jan-16 Radboud
Sen
University;
Radboud
University
Medical Centre
Optimal Treatment for Spinal Cord Procedure: Early
Spinal Cord Injury
Injury Associated With Cervical
surgery; Procedure:
Canal Stenosis (OSCIS) Study
Delayed surgery
study
NCT01485458
Evaluating Vertebroplasty and
Procedure:
Vertebral Body
Kyphoplasty for Reducing Trauma- Kyphoplasty;
Compression
related Fractures
Procedure:
Fractures
RCT, efficacy study
Vertebroplasty
NCT01402167
Vertebroplasty Compared With a Procedure:
Osteoporotic
Sham-procedure for Painful Acute Percutaneous
Fractures
Osteoporotic Vertebral Fractures vertebroplasty;
Procedure: Lidocaine
NCT01537770
injection
Vertebroplasty Compared With a Procedure:
Osteoporotic
Sham-procedure for Painful Acute Percutaneous
Fractures
Osteoporotic Vertebral Fractures vertebroplasty;
Procedure: Lidocaine
NCT01537770
injection
A Trial of Vertebroplasty for Painful Procedure:
Osteoporosis;
Acute Osteoporotic Vertebral
percutaneous
Vertebral Fracture
Fractures
vertebroplasty;
Procedure: sham
NCT01200277
procedure
A Trial of Vertebroplasty for Painful Procedure:
Osteoporosis;
percutaneous
Vertebral Fracture
Fractures
vertebroplasty;
Procedure: sham
NCT01200277
procedure
Surgical Versus Nonoperative
Procedure: Surgical Metastatic Epidural
Treatment of Metastatic Epidural excision of the
Spinal Cord
Spinal Cord Compression
metastatic process; Compression
Radiation:
study
Radiotherapy of the
NCT00634426
metastatic spine
process
Rec
100
Adt Dec-11 Dec-14 Tokyo University http://ClinicalTrials.gov/show/NCT01485458
Sen
Not yet
Rec
30
Adt Mar-12 Mar-14 Centre
Sen
Hospitalier
Universitaire de
Nīmes
Rec
80
Rec
80
Rec
80
Adt Feb-12 Jan-14 Sygehus
Sen
Lillebaelt;
Odense
University
Hospital
Adt Feb-12 Jan-14 Sygehus
Sen
Lillebaelt;
Odense
University
Hospital
Adt Jan-11 Jan-14 St. Elisabeth
Sen
Hospital, Tilburg,
Netherlands
Rec
80
Adt Jan-11 Jan-14 St. Elisabeth
Sen
Hospital, Tilburg,
Netherlands
Rec
432
Adt Mar-08 Oct-13 AO Clinical
Sen
Investigation and
Documentation;
AOSpine North
America
28
The role of early surgery in
patients paralysed following injury
RCT
ISRCTN61263382
Surgical
Spinal Cord Injury
decompression of
compressed spinal
cord and
stabilisation: late vs
early
Procedure:
Spinal Cord Injury
Somatosensory
reflex arch (Xiao
Procedure)
Somato-sensory Reflex Arch in
Spinal Cord Injury - Effect on
Clinical Outcome
NCT01241630
A Controlled Trial of Vertebroplasty Procedure:
for Acute Painful Osteoporotic
Vertebroplasty
Fractures
RCT, efficacy study
NCT01482793
A Controlled Trial of Vertebroplasty Procedure:
for Acute Painful Osteoporotic
Vertebroplasty
Fractures
RCT, efficacy study
NCT01482793
Somato-sensory Reflex Arch in
Spinal Cord Injury - Effect on
Colorectal Transport
NCT01274312
Evaluation of Wire Electrodes to
Activate the Expiratory Muscles to
Restore Cough
NCT00995215
Procedure: Xiao
procedure
Procedure: Spinal
Cord Stimulation
Active
328
Adt May-09 May-13 Sina Trauma
and Surgery
Research Centre
(Iran)
Rec
20
Adt Nov-09 Apr-13 University of
Sen
Aarhus;
Lundbeck
Foundation
Vertebral
Compression
Fractures;
Osteoporotic
Vertebral
Compression
Fractures; Acute
Vertebral Fractures
Vertebral
Compression
Fractures;
Osteoporotic
Vertebral
Compression
Fractures; Acute
Vertebral Fractures
Rec
120
Adt Nov-11 Apr-13 Optimus Clinical http://ClinicalTrials.gov/show/NCT01482793
Sen
Research; Care
Fusion
Rec
120
Adt Nov-11 Apr-13 Optimus Clinical http://ClinicalTrials.gov/show/NCT01482793
Sen
Research; Care
Fusion
Rec
20
Sen
Aarhus;
Lundbeck
Foundation
Spinal Cord
Diseases; Paralysis;
Central Nervous
System Diseases;
Cough
Rec
6
Adt Oct-09 Mar-13 Case Western http://ClinicalTrials.gov/show/NCT00995215
Sen
Reserve
University;
National Institute
of Neurological
Disorders and
Stroke (NINDS)
29
Spinal Cord Stimulation to Restore Procedure: Spinal
Cough
Cord Stimulation
NCT00116337
18
Adt Sep-04 Mar-13 Case Western http://ClinicalTrials.gov/show/NCT00116337
Sen
Reserve
University;
National Institute
of Neurological
Disorders and
Stroke (NINDS)
Autologous Bone Marrow Stem
Cell Transplantation in Patients
With Spinal Cord Injury
study
NCT01325103
Rec
Spinal Cord
Diseases; Paralysis;
Central Nervous
System Diseases;
Cough; Trauma,
Nervous System;
Wounds and Injuries
Procedure: Stem Cell Spinal Cord Injury
Active,
Transplantation
NR
20
Adt
Procedure:
Conventional
Treatment; Drug:
Lithium Carbonate;
Biological: Cord
Blood Cell; Other:
Placebo
Procedure: Mantis;
Procedure: XIA
Spinal Cord Injury
Rec
60
Vertebral Fracture
Rec
100
Dorsal or dorsoventral stabilisation
of spine fractures
Spine fractures
active
60
Adt Sep-09 Sep-12 Centre for Spinal http://www.controlledSurgery and
Brain Trauma,
Germany
Procedure:
Discectomy with
anular repair
Diskectomy
750
Adt Mar-07 Jan-12 Anulex
Sen
Technologies,
Inc.
Lithium, Cord Blood Cells and the
Combination in the Treatment of
Acute & Sub-acute Spinal Cord
Injury
study
NCT01471613
Identification of Microcirculation
and Inflammation After Posterior
Stabilization of the Spine
RCT
NCT01266200
Treatment of incomplete burst
fractures (AO Type A3.1) with
dorsal or dorso-ventral proceeding
RCT, case-control
ISRCTN92182348
Randomized Study of Anular
Repair With the Xclose Tissue
Repair System
NCT00760799
Active,
NR
30
Jul-10 Jan-13 Hospital Sao
Rafael; Oswaldo
Cruz
Foundation; Irep
Sociedade de
Ensino Superior
Médio e
Fundamental
Limitada;
Hospital
Espanhol
Adt Sep-11 Dec-12 China Spinal
Cord Injury
Network;
Chengdu PLA
General
Hospital;
StemCyte, Inc.
Adt Dec-10 Dec-12 RWTH Aachen http://ClinicalTrials.gov/show/NCT01266200
Sen
University
Evaluation of a Tongue Operated Procedure: Tongue Quadriplegia; Spinal
Assistive Technology for
Piercing; Device:
Cord Injury; ALS
Individuals With Severe Paralysis Usability assessment
Phase I: Non-randomized,
NCT01124292
Cost Effectiveness and Efficacy of
Kyphoplasty and Vertebroplasty
Trial
study
NCT00279877
Cost Effectiveness and Efficacy of
Kyphoplasty and Vertebroplasty
Trial
study
NCT00279877
KAVIAR Study - Kyphoplasty And
Vertebroplasty In the
Augmentation and Restoration of
Vertebral Body Compression
Fractures
study
NCT00323609
Transplantation of Autologous
Olfactory Ensheathing Cells in
Complete Human Spinal Cord
Injury
Phase I: Non-randomized,
NCT01231893
Rec
70
Adt May-10 Dec-11 Georgia Institute http://ClinicalTrials.gov/show/NCT01124292
of Technology;
Shepherd
Center;
Northwestern
University;
Rehabilitation
Institute of
Chicago;
University of
Arizona
Adt May-05 Aug-11 Mayo Clinic;
Sen
Cardinal;
ArthroCare
Corporation;
Cook
Procedure:
Kyphoplasty
Osteoporotic
Vertebral
Compression
Fractures
Active,
NR
112
Procedure:
Kyphoplasty
Osteoporotic
Vertebral
Compression
Fractures
Active,
NR
112
Adt May-05 Aug-11 Mayo Clinic;
Sen
Cardinal;
ArthroCare
Corporation;
Cook
Procedure:
Vertebroplasty;
Procedure:
Kyphoplasty
Vertebral Body
Compression
Fractures
Term
404
Adt Aug-06 Jul-11 Medtronic Spine http://ClinicalTrials.gov/show/NCT00323609
Sen
LLC
Rec
10
Child May-08 Oct-10 Wroclaw Medical http://ClinicalTrials.gov/show/NCT01231893
Adt
University;
Institute of
Immunology and
Experimental
Therapy of the
Polish Academy
of Sciences;
Department of
Rehabilitation in
Spinal Cord
Injuries Akson
Procedure: olfactory Complete Spinal
mucosa ensheathing Cord Injuries
cell grafting,
rehabilitation
31
Safety and Efficacy of Autologous
Bone Marrow Stem Cells in
Treating Spinal Cord Injury
Phase I/II: Non-randomized,
NCT01186679
Quality of Life After Vertebroplasty
Versus Conservative Treatment in
Patients With Painful Osteoporotic
Vertebral Fractures
RCT, efficacy study
NCT00994032
Quality of Life After Vertebroplasty
Versus Conservative Treatment in
Patients With Painful Osteoporotic
Vertebral Fractures
RCT, efficacy study
NCT00994032
Surgical Management of Spinal
Cord Injuries In Neck
study
NCT00475748
Procedure:
laminectomy;
Procedure:
Intrathecal
Anderson Circulating Tumor Cell
Burden (CTCB) Study
study
NCT00819832
Treatment for Acute Spinal Cord
Injury
study
NCT00695149
Functional Electrical Stimulation
for Production of Artificial Cough
NCT00589199
Comp
12
Adt
Procedure:
Spinal Fracture;
percutaneous
Osteoporosis; Back
injection of cement Pain
into the vertebral
body; Other: Medical
treatment
Procedure:
Spinal Fracture;
percutaneous
Osteoporosis; Back
injection of cement Pain
into the vertebral
body; Other: Medical
treatment
Procedure: Early and Central Cord
late surgery for
Syndrome; Spinal
traumatic central
Cord Injury;
cord syndrome
Quadriparesis
Active,
NR
100
Active,
NR
100
Active,
NR
30
Procedure:
Cancer; Spinal
Kyphoplasty;
Disease; Vertebral
Procedure:
Compression
Vertebroplasty;
Fractures
Device: Cavity
SpineWand
Procedure:
Spinal Cord Injury
Transplantation of
bone marrow stromal
cell
Term
3
Adt Mar-06 Jun-10 Hospital Clinic of
Sen
Barcelona;
Sociedad
Española de
Radiologia
Medica
Adt Mar-06 Jun-10 Hospital Clinic of
Sen
Barcelona;
Sociedad
Española de
Radiologia
Medica
Adt May-07 May-10 Maryland
Sen
Department of
Health and
Mental Hygiene;
University of
Maryland
Adt Dec-08 May-10 M.D. Anderson
Sen
Cancer Center;
ArthroCare
Corporation
Term
5
Child Jul-05 Mar-10 Translational
Adt
Research
Informatics
Center, Kobe,
Hyogo, Japan
Procedure:
Placement and use
of the device
Comp
5
Paralysis
32
Jan-08 Aug-10 International
Stemcell
Services Limited
Adt Dec-93 Jan-10 Case Western
Reserve
University;
MetroHealth
Medical Center
Other
C-STOP Fracture Trial
study
NCT01401556
Other: case
Osteoporosis
management; Other:
Multifaceted quality
improvement
intervention
To Study the Safety and Efficacy Other: Autologous
Spinal Cord Injury
of Autologous Bone Marrow Stem Bone Marrow derived
Cells in Patients With Spinal Cord Stem Cells
Injury
study
NCT01490242
Nuclear MRI(NMR)in Women at
Radiation: Virtual
Osteoporosis,
Risk of Fracture Receiving Either Bone Biopsy by
Osteopenia
Zoledronic Acid or Teriparatide
Magnetic Resonance
RCT, efficacy study
Imaging
NCT01153425
Kyphoplasty, Vertebroplasty and
Conservative Management in
Fractures
NCT00749060
Comparative Study of Balloon
Kyphoplasty and Conservative
Treatment
study
NCT00749242
Other: conventional
treatment;
Procedure:
kyphoplasty with
balloons; Procedure:
vertebroplasty
Osteoporotic
Vertebral Fracture;
Between T5 and L5;
of Less Than 6
Weeks Duration
Other: orthopedic
SPINAL Fracture
corset; Device:
balloon kyphoplasty
Not yet 220
Rec
Adt
Sen
Jul-11
Jul-15 University of
Alberta
Oct-11 Oct-13 TotipotentRX
Cell Therapy
Pvt. Ltd.; Fortis
Healthcare
Rec
15
Adt
Active,
NR
56
Adt
Sen
200
Sen
Paris; Ministry of
Health, France
Rec
Rec
Jul-08 Jun-13 University of
Pennsylvania;
Eli Lilly and
FCompany;
only
Novartis
Pharmaceuticals
300 Adt Dec-07 Dec-12 Assistance
Sen
Paris; Ministry of
Health, France
33
The Effects of Two Functional
Other: Cycling with
Electrical Stimulation Cycling
functional electrical
Paradigms
stimulation
Phase II/III: RCT, efficacy study
NCT01244594
Spinal Cord Injury
Rec
20
Adt
Jul-10
Jul-12 University of the http://ClinicalTrials.gov/show/NCT01244594
Sciences in
Philadelphia;
The Craig H.
Neilsen
Foundation;
Thomas
Jefferson
University;
Magee
Rehabilitation
Hospital; Temple
University;
University of
Delaware
Active, 2000 Adt Jun-08 Dec-11 University of
NR
Sen
Manitoba; The
Manitoba Patient
Access Network
Steering
Committee; The
Manitoba Bone
Density Program
Committee
Active, 180 Adt May-08 Jul-11 University of
NR
Kansas
Closing The Post Fracture Care
Gap In Manitoba
RCT
NCT00594789
Other: Information
letters
Osteoporosis
A Randomized Exercise Trial for
Wheelchair Users
RCT, efficacy study
NCT00866112
Other: Educational
session to promote
physical activity;
Other: Minimal
contact
The Prevalence of Osteoporotic
Vertebral Compression Fractures
(OVCF) in Korean Post
Menopausal Women
Cross-sectional study
NCT01381588
Radiological Biological Genetic
and Micro-architectural Bone
Determinants of Fractures in Men
With Low Bone Mineral Density
assignment
NCT01250314
Other: Fracture
evaluation
Spinal Cord Injury;
Multiple Sclerosis;
Muscular Dystrophy;
Cerebral Palsy;
Spina Bifida;
Amputation; Arthritis;
Stroke
Osteoporosis,
Comp 1136 Adt Oct-10 Feb-11 GlaxoSmithKline http://ClinicalTrials.gov/show/NCT01381588
Postmenopausal
Sen
Fonly
Other: Radiology;
Other: Biological,
biochemical and
genetic samples
Osteoporosis
Rec
200
34
Adt Feb-08 Feb-11 Assistance
Sen
Paris; Ministry of
Health, France
Study of Sacral Fractures Using
Patient Based and Objective
Outcomes
NCT00798733
Utility of CT Fluoroscopy Guidance
During Percutaneous Sacroplasty
With Quality of Life Assessment
NCT00765258
Characterization of At-risk
Population for Pre-sacral Tumor in
CURRARINO Syndrome
NCT00780117
High-Resolution Diffusion Tensor
Imaging (DTI) of the Cervical
Spinal Cord in the Setting of Spinal
Cord Injury (SCI)
NCT01407705
The Natural History of Traumatic
Spinal Cord Injury Using fMRI,
MRS and DTI
NCT00790361
Evaluation of Circulating
Osteogenic Factors in Trauma
Patients
Cross-sectional, cohort study
NCT01433536
Sacrum Fracture
Rec
Sacro-Iliac
Insufficiency
Fractures
Rec
1000 Adt Oct-08 Dec-14 Boston Medical http://ClinicalTrials.gov/show/NCT00798733
Sen
Center;
Foundation of
Orthopedic
Trauma
100 Adt Jan-08 Dec-14 Medical College http://ClinicalTrials.gov/show/NCT00765258
Sen
of Wisconsin;
Montefiore
Medical Center
CURRARINO
Rec
Syndrome;
Sacrococcygeal
Teratoma; Presacral
Mass
Spinal Cord Injury;
Invite
Cervical Spondylosis
With Myelopathy;
Degenerative
Disorder
80
Child Jun-08 Sep-14 Assistance
Adt
Publique Sen
Hôpitaux de
Paris
70
Adt May-07 Feb-13 University of
Sen
Utah
Central Cord
Syndrome
Not yet
Rec
20
Rec
60
Adt Jan-12 Jan-13 Lawson Health http://ClinicalTrials.gov/show/NCT00790361
Sen
Research
Institute; The
Physicians'
Services
Incorporated
Foundation
Adt Dec-10 Sep-11 Centre
Hospitalier
Universitaire de
Sherbrooke;
Universitaire de
Sherbrooke;
Canadian
Institutes of
Health Research
Healthy; High
Velocity Fracture;
Cranial Trauma;
Spinal Trauma
35
A3C: OTHER
Title
CT ID
Behavioural
Short Versus Long Post-Operative
Restrictions Following Lumbar
Discectomy
RCT, efficacy study
NCT01363830
Interventions
Cognitive-Behavioral Physical
Therapy Intervention
Phase I/II: RCT, efficacy study
NCT01131611
Helping Patients With Spinal
Stenosis Make a Treatment
Decision: A Randomized Study
Assessing The Benefits of Health
Coaching
RCT
NCT01263678
Function After Spinal Treatment,
Exercise and Rehabilitation:
Improving the functional outcome
of spinal surgery
RCT
ISRCTN46782945
Behavioral: CBPT;
Other: Physical
Therapy
Device
Evaluate Initial Safety of the
HemiBridge™ System in Guided
Spinal Growth Treatment of
Progressive Idiopathic Scoliosis
study
NCT01465295
Conditions
Recruit
n
Rec
420
Not yet
Rec
70
Behavioral: Post DA Spinal Stenosis
viewing coaching;
Other: Usual Care
Invite
Rehabilitation
Programme;
Exercise booklet
Behavioral: TwoLumbar Disc
Week Post-Operative Herniation
Restriction;
Behavioral: SixWeek Post-Operative
Restriction
Spinal Stenosis
Spinal lateral root
stenosis and
discectomy
Device: Mechanical Scoliosis
hemiepiphysiodesis
using the
HemiBridge System
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt Aug-09 Dec-13 Brigham and
Sen
Women's
Hospital;
Massachusetts
General
Hospital; Beth
Israel
Deaconess
Medical Center
Adt Jan-12 Aug-13 Vanderbilt
Sen
University
200
Adt Nov-10 Nov-11 DartmouthSen
Hitchcock
Medical Center
Comp
344
Adt Apr-05 Mar-10 Arthritis
Sen
Research
Campaign
(ARC) (UK)
Rec
6
36
Child Aug-11 Jan-21 SpineForm LLC; http://ClinicalTrials.gov/show/NCT01465295
Adt
Children's
Sen
Hospital Medical
Center,
Cincinnati;
University
Hospital Case
Medical Center
Safety and Performance of the
Elaspine System in the Treatment
of the Lumbar Spine
NCT01323543
Minuteman Spinal Fusion Implant
Versus Surgical Decompression
for Lumbar Spinal Stenosis
study
NCT01455805
Condition of Approval Study
study
NCT00517751
INFUSE®Bone Graft in
Transforaminal Lumbar Interbody
Fusion for Degenerative Disease
of Lumbosacral Spine
NCT01415908
Intra-Operative Dural
Brachytherapy With Yttrium-90
Plaque Applicators
NCT00706485
Device: Elaspine™
Lower Back Pain
Rec
40
Device: Minuteman
Interspinous
Interlaminar Fusion
Implant; Procedure:
surgical
decompression
Device: X-STOP
PEEK
Lumbar Spinal
Stenosis;
Spondylolisthesis;
Degenerative Disc
Disease
Lumbar Spinal
Stenosis
Rec
240
Adt Aug-07 Dec-18 Medtronic Spine http://ClinicalTrials.gov/show/NCT00517751
Sen
LLC
Device: INFUSE
Bone Graft; Other:
Iliac Crest Bone
Graft
Lumbar Spine
Degeneration
Rec
534
Adt
Sen
Jul-11
Device: Yttrium-90
Plaque Applicator
Spinal Neoplasms
Susp
10
Adt
Sen
Jul-07
Spinal Cord Stimulation With
Precision® SCS System Versus
Reoperation for Failed Back
Surgery Syndrome
NCT01036529
Device: Precision
Spinal Cord
Stimulation;
Procedure: Back
Surgery
Failed Back Surgery
Syndrome; Leg Pain;
Back Pain; Spinal
Cord Stimulation
Rec
132
Not yet 180
Rec
37
Adt Aug-10 Dec-20 Spinelab AG;
Sen
MDT Medical
Device Testing
GmbH
Adt Jan-12 Dec-19 Spinal Simplicity http://ClinicalTrials.gov/show/NCT01455805
Sen
LLC; The Leeds
Teaching
Hospitals NHS
Trust
Jul-17 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01415908
and Biologics
Jul-17 Massachusetts http://ClinicalTrials.gov/show/NCT00706485
General
Hospital;
National
Institutes of
Health; Implant
Sciences
Adt Feb-10 Mar-17 Boston Scientific http://ClinicalTrials.gov/show/NCT01036529
Sen
Corporation
Effect of Human Thrombin With
Gelatin Matrix on Perioperative
Blood Loss in Scoliosis Surgery
NCT01451788
Device: Gelatin
matrix with human
derived thrombin
(Floseal, Baxter)
Adolescent
Dynesys Spinal System Post
Market 522 Study
Efficacy study
NCT01528072
A Clinical Study of the Dynesys(R)
Spinal System
study
NCT00759057
DuraSeal Exact Spine Sealant
System Post-Approval Study
Phase IV: Cohort study
NCT01410864
Kineflex/C Artificial Disc System to
Treat Cervical Degenerative Disc
Disease (DDD)
NCT00374413
Comparison of the Aspen Device
Versus Pedicle Screws for
Supplemental Posterior Fixation in
Lumbar Interbody Fusion
NCT01549366
Kineflex Artificial Disc System to
Treat Degenerative Disc Disease
(DDD)
NCT00292292
Device: Dynesys
Spinal System
Degenerative
Spondylolisthesis;
Pseudoarthrosis
Rec
60
Child Nov-11 Dec-16 Turku University http://ClinicalTrials.gov/show/NCT01451788
Adt
Hospital;
Tampere
University
Hospital;
Helsinki
University
Central Hospital
Not yet 168 Adt Mar-12 Mar-16 Zimmer, Inc.
Rec
Sen
Device: Posterior
Pedicle Screw
System
Degenerative
Active, 399
Spondylolisthesis or
NR
Retrolisthesis; Spinal
Stenosis; Stenosing
Lesion.
Device: DuraSeal
Dural Sealing
Not yet 1044
Exact Spine Sealant
Rec
System; Other:
Control
Device: Artificial disk; Degenerative Disc
Active, 343
Device: Artificial disc Disease (DDD)
NR
Adt Mar-03 Dec-15 Zimmer, Inc.
Sen
Adt Aug-11 Sep-15 Covidien
Sen
Adt
Device: Aspen
Spinous Process
Fixation Device;
Device: Pedicle
Screw Fixation
Degenerative Disc
Disease (DDD)
Rec
144
Adt Feb-12 May-15 Lanx, Inc.
Sen
Device: Lumbar
Artificial Disc;
Device: Charite
Artificial Disc
Degenerative Disc
Disease
Active,
NR
514
Adt
38
Jul-05 Aug-15 SpinalMotion
Jan-05 Mar-15 SpinalMotion
Device: DIAM™
Effectiveness of DIAM™ Spinal
Spinal Stabilization
Stabilization System Versus
System; Procedure:
Conservative Care
Conservative care
study
NCT00456378
The iO-Flex® Study: Evaluation of Device: Baxano iOthe Baxano iO-Flex® System for Flex® System
Decompressive Lumbar Surgery
NCT01067014
Performance of Inductigraft in
Device: Inductigraft
Spinal Fusion
study
NCT01452022
Trial Assessing Cooled
Device: Sinergy;
Radiofrequency Denervation as a Device: Placebo
Treatment for Sacroiliac Joint Pain sham
Using the Sinergy System
RCT, efficacy study
NCT00802997
Wallis Stabilization System for Low Interspinous process
Back Pain
& dynamic
stabilization (Wallis
study
System); Total Disc
NCT00484458
Replacement
Proximal Junctional Kyphosis
Device: Semi rigid
Following Long Instrumented
rod; Device: Rigid
Spinal Fusion: The Effect of
Rod
Implant Selection
NCT01441999
A Postmarket Surveillance Study Device: Dynamic
of the Paradigm Spine Dynamic
Stabilization System
Stabilization System (DSS)
(DSS)
study
NCT01461005
Rec
306
Adt Dec-06 Feb-15 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00456378
Sen
and Biologics
Invite
75
Adt Feb-10 Dec-14 Baxano, Inc.
Sen
Degenerative Disk
Disease; Spinal
Stenosis of Lumbar
Region
Rec
230
Adt Oct-11 Dec-14 Apatech, Inc.
Sen
Sacroiliac Pain
Rec
51
Adt Jun-08 Dec-14 Coastal
Sen
Orthopedics &
Sports Medicine
Low Back Pain
Active,
NR
340
Adt
Junctional Kyphosis Not yet
Rec
24
Adt Oct-11 Sep-14 Globus Medical http://ClinicalTrials.gov/show/NCT01441999
Sen
Inc (US)
Spondylolisthesis;
Neurologic Deficits;
Kyphosis;
Pseudarthrosis
150
Adt Sep-11 Jul-14 Paradigm Spine; http://ClinicalTrials.gov/show/NCT01461005
Sen
Musculoskeletal
Clinical
Regulatory
Advisers LLC
Lumbar
Degenerative Disc
Disease
Lumbar Spinal
Stenosis
Rec
39
Jan-07 Nov-14 Zimmer Spine;
Zimmer, Inc.
A Prospective, Randomized,
Multicenter Study to Demonstrate
the Superiority of the Barricaid to
Discectomy for Primary Lumbar
Disc Herniation
Phase IV: RCT
NCT01283438
Clinical Trial Comparing
Decompression With and Without
Coflex™ Treating Lumbar Spinal
Stenosis
NCT01316211
SMART Clinical Study: Surgical
Multi-center Assessment of RF
Ablation for the Treatment of
Vertebrogenic Back Pain
NCT01446419
Scoliosis Surgery Using the
PASS® LP System
study
NCT01019109
Trial Evaluating the Safety and
Effectiveness of NUBAC™ Disc
Arthroplasty
NCT00931515
Bone Graft Materials
Observational Registry
NCT00974623
Device: Barricaid;
Lumbar Disc
Device: Standard of Herniation
Care
Rec
400
Adt Dec-10 May-14 Intrinsic
Sen
Therapeutics
Device: Implantation Spinal Stenosis
of coflex™ after
surgical
decompression;
Procedure: Surgical
decompression
Device: Intracept
Low Back Pain
Treatment; Device:
Intracept Treatment
Rec
230
Adt Jun-07 May-14 Paradigm Spine; http://ClinicalTrials.gov/show/NCT01316211
Sen
MDT Medical
Device Testing
GmbH
Rec
200
Adt Oct-11 Apr-14 Relievant
Sen
Medsystems,
Inc.
Device: Posterior
Spinal Fusion Device
Rec
120 Child May-10 Mar-14 Medicrea, USA
Adt
Corp.
Sen
Device: NUBAC™ vs Degenerative Disc
ProDisc™
Disease
Active,
NR
400
Adt Feb-09 Feb-14 Pioneer Surgical http://ClinicalTrials.gov/show/NCT00931515
Sen
Technology, Inc.
Rec
300
Adt Sep-09 Dec-13 Apatech, Inc.
Sen
Device: Bone graft Degenerative Disc
substitute, autograft Disease; Herniated
or allograft
Disc; Spinal
Stenosis;
Spondylolithesis;
Spinal Deformity;
Cervical Myelopathy;
Failed Back Surgery
Syndrome; Spinal
Cord Neoplasms
40
Efficacy and Safety of Accell Evo3
DBM in Instrumented
Posterolateral Lumbar Spine
Fusion
NCT01430299
Investigating Superion™ In Spinal
Stenosis [ISISS]
NCT00692276
Device: Integra
Accell Evo3
Stenosis;
Spondylosis;
Degenerative
Changes
Rec
30
Adt Jun-11 Dec-13 Integra
Sen
LifeSciences
Corporation
Device: Superion™
Interspinous Spacer;
Device: X-STOP®
IPD® Device
Lumbar Spinal
Stenosis;
Neurogenic
Intermittent
Claudication
Lumbar Spinal
Stenosis
Rec
400
Adt Jun-08 Dec-13 VertiFlex,
Sen
Incorporated
Rec
300
Adt Oct-06 Oct-13 Facet Solutions, http://ClinicalTrials.gov/show/NCT00401518
Sen
Inc.
Active,
NR
45
Adt Apr-09 Aug-13 Intrinsic
Sen
Therapeutics
A Pivotal Study of a Facet
Device: Facet
Replacement System to Treat
Arthroplasty
Spinal Stenosis
study
NCT00401518
Barricaid EU Post Market Study for Device: Barricaid
Lumbar Disc
Primary Lumbar Disc Herniation
Herniation
assignment
NCT01534065
Prospective, Multi-Center Clinical Device: chronOS
Degenerative Disc
Outcomes Study Evaluating the
strip
Disease With or
chronOS Strip Combined With
Without Stenosis
Bone Marrow Aspirate
NCT00943384
Study Of The Efficacy Of
Device: Neurotome Low Back Pain
Neurolysis In Functional Recovery OFF; Procedure:
From Chronic Nonspecific Low
neurolysis
Back Pain
RCT, efficacy study
NCT01190033
Study of Bioactive Glass-ceramic Device: 4 CIS one- Degenerative Disk
Intervertebral Spacer (Bonglass- touch titanium cage; Disease
SS) in Posterior Lumbar Interbody Device: Bonglass-SS
Fusion
SSLPB
RCT, efficacy study
NCT01439464
Active,
NR
Monly
102 Adt Jul-09
Sen
Jul-13 Synthes USA
HQ, Inc.
Rec
40
Adt Aug-10 Jul-13 University of Sao http://ClinicalTrials.gov/show/NCT01190033
Paulo
Rec
86
Adt Oct-10 Jun-13 BioAlpha Inc.
Sen
41
Post-Operative Colonization Rates
of Femoral Nerve Catheters
Treated With ChlorhexidineImpregnated Patch
Phase IV: RCT, safety study
NCT01411891
Device:
Chlorhexidine
impregnated patch
(Biopatch)
Spine Reference Parameters on Device: EOS™
EOS Imaging
Acquisition
NCT01406743
Safety and Efficacy of the
Device: TransDiscal
TransDiscal System Versus
System; Other:
Medical Management in Treating Medical
Chronic Discogenic Low Back Pain Management
study
NCT01263054
Salient Aquamantys Spine Trial
Device: Bipolar
Sealer
NCT01331499
(Aquamantys);
Procedure: Standard
of Care
Herniectomy Versus Herniectomy Device: DIAM™
With a Spinal Stabilization System Spinal Stabilization
for the Treatment of Complex Disc System; Procedure:
Disease
Herniectomy
NCT00749996
LDR Spine USA Mobi-C(R)
Device: Cervical
Cervical Disc Prosthesis IDE
Artificial Disc
study
NCT00389597
Evaluation of an 3D Imaging
Device: Navigation
Intensifier Coupled to a Navigation station coupled with
Station in the Surgery of the Spine a 3D fluoroscopy
and Pelvis
study
NCT01335841
Catheter Infections;
Spinal Catheter
(Epidural)
(Subdural);
Complications,
Infection or
Inflammation
Healthy Volunteers
Rec
100
Adt Aug-11 Jun-13 University of
Sen
Wisconsin,
Madison
Rec
204
Adt May-11 May-13 University
Sen
Hospital,
Bordeaux
Back Pain
Rec
136
Adt Dec-10 May-13 Kimberly-Clark
Sen
Corporation
Blood Loss
Rec
128
Adt Apr-11 Apr-13 Salient Surgical http://ClinicalTrials.gov/show/NCT01331499
Sen
Technologies
Sciatica; Lumbar
Degenerative Disc
Disease
Active,
NR
165
Adt Nov-06 Apr-13 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00749996
& Biologics ECA
Degenerative Disc
Disease
Active,
NR
600
Adt Apr-06 Mar-13 LDR Spine USA http://ClinicalTrials.gov/show/NCT00389597
Sen
Rec
150
Adt Mar-11 Mar-13 AdministrateurCI http://ClinicalTrials.gov/show/NCT01335841
Sen
C; PRAXIM
company
Surgical Procedure,
Unspecified
42
Clinical Outcomes of the Trinica(R) Device: Trinica
Degenerative Disc
Anterior Lumbar Plate: Fixed
Anterior Lumbar
Disease; Spinal
Screws vs. Variable Screws
Plate System
Stenosis;
RCT
Spondylolisthesis
NCT00762723
Senza™ spinal cord stimulation
Senza™ spinal cord Chronic back and
system for the treatment of chronic stimulation system leg pain in failed
back and leg pain in failed back
back surgery
surgery syndrome (FBSS) patients
syndrome (FBSS)
RCT
patients
ISRCTN33292457 SS) patients
The Use of Dermabond Versus
Device: 2Wounds
Standard Staple for Wound
octylcyanoacrylate
Closure in Children With
(Dermabond)
Neuromuscular Scoliosis
closure; Device:
Undergoing Spinal Deformity
Standard staple
Correction Surgery
closure
study
NCT01135940
Freedom Lumbar Disc in the
Device: FLD; Device: Degenerative Disc
Treatment of Lumbar Degenerative Control
Disease (DDD)
Disc Disease
NCT00775801
INFUSE® Bone Graft/ PEEK
Device: INFUSE®
Degenerative Disc
Interbody Spacer/ Anterior Cervical Bone Graft/PEEK
Disease
Plate Pivotal Clinical Trial
Spacer/Anterior
Cervical Plate
study
NCT00485173
Efficacy of the Aspen Spinous
Device: Aspen
Degenerative Disc
Process System in Anterior
Spinous Process
Disease
Lumbar Interbody Fusion (ALIF)
System; Device:
Phase IV: RCT
Pedicle Screw
NCT01016314
Fixation
Active,
NR
120 Child Feb-08 Feb-13 Zimmer, Inc.
Adt
Sen
Active
20
Adt Apr-11 Dec-12 Nevro
Sen
Corporation
(USA)
Rec
80
Child May-10 Dec-12 University of
Adt
British Columbia;
BCCH Telethon
Grant
Rec
300
Adt Sep-08 Dec-12 AxioMed Spine
Corporation
Active,
NR
225
Adt Jun-07 Dec-12 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00485173
Sen
and Biologics
Rec
156
Adt Nov-09 Nov-12 Lanx, Inc.
Sen
43
Safety and Effectiveness Study of Device: AO-1000
Disk, Herniated
the AO-1000 Device to Treat
Contained Herniated Discs
study
NCT01339377
Pilot Study to Assess
Device: Prefix
Degenerative Disc
Safety/Preliminary Effectiveness of (AMPLEX) B2A
Disease;
Prefix in Subjects With
Peptide Enhanced Spondylolisthesis
Degenerative Disc Disease (DDD) Ceramic Granules;
Undergoing Spine Fusion Surgery Other: Iliac crest
Phase I/II: RCT, safety/efficacy autograft
study
NCT00798902
Comparison of Standard Fusion
Device: Topping off Spondylolisthesis;
With “Topping Off”-System in
system; Device:
Erosive
Lumbar Spine"
monosegmental PLIF Osteochondrosis in
L2-S1
NCT01224379
Mild® Decompression Alternative Device: mild®
Lumbar Spinal
to Open Surgery Epidural Steroid Lumbar
Stenosis
Injection Comparative Outcomes Decompression;
Study
Drug: Epidural
RCT
Steroid Injection
NCT01315145
Adjunctive Biofeedback
Device: StressEraser Post-traumatic
Intervention for Operation Iraqi
Stress Disorder
Freedom/Operation Enduring
Freedom (OIF-OEF) Post
Traumatic Stress Disorder (PTSD)
RCT, efficacy study
NCT00920036
Cervical Spine; Movement Before Device: Activ C disc Diskectomy;
and After Anterior Cervical
prosthesis;
Intervertebral Disk
Discectomy, With or Without a
Procedure: Anterior Displacement
Cervical Disc Prosthesis
cervical discectomy
RCT, efficacy study
NCT00868335
Rec
40
Adt Aug-11 Oct-12 ActiveO Inc.
Sen
Active,
NR
22
Adt Nov-08 Oct-12 BioSurface
Sen
Engineering
Technologies,
Inc
Not yet
Rec
30
Adt Jan-11 Oct-12 University of
Sen
Cologne
Rec
200
Adt Mar-11 Sep-12 Vertos Medical, http://ClinicalTrials.gov/show/NCT01315145
Sen
Inc.
Active,
NR
30
Adt Feb-10 Sep-12 Department of http://ClinicalTrials.gov/show/NCT00920036
Sen
Veterans Affairs
Rec
24
Adt Dec-07 Aug-12 Maastricht
University
Medical Center;
B. Braun/
Aesculap Spine
44
Efficacy Study of the Octapolar
Device: Octad® lead
Lead in Patients With Failed Back (Spinal cord
Surgery Syndrome (FBSS) With
stimulation)
Chronic Pain
study
NCT01096147
Blue Light Device for Pain Therapy Device: Pain Relief
Patch; Device:
NCT01528332
Control PRP device
Pilot Study to Assess
Safety/Prelimary Effectiveness of
Prefix in Subjects With
Degenerative Disc Disease (DDD)
Undergoing Spine Fusion Surgery
study
NCT00798239
Failed Back Surgery
Syndrome
Rec
Low Back Pain; Low Rec
Back Pain,
Recurrent;
Musculoskeletal
Pain; Chronic Pain
Degenerative Disc
Active,
Disease;
NR
Spondylolisthesis
Device: Prefix
(AMPLEX) B2A
Peptide Enhanced
Ceramic Granules;
Other: Iliac crest
autograft; Device:
Prefix (AMPLEX)
B2A Peptide
Enhanced Ceramic
Granules
XL TDR® eXtreme Lateral Total Device: XL TDR;
Degenerative Disc
Disc Replacement for the
Other: Lumbar fusion Disease
Treatment of Lumbar Degenerative surgery
Disc Disease (DDD)
study
NCT00927238
PSU Lumbar Support for
Device: PSU lumbar Low Back Pain
Prevention of Low Back Pain in
back support
Rubber Tapper
NCT01017588
CNAP™ Monitor Study
Device: CNAP
Cardiac Surgery;
Spinal Surgery
NCT01356082
300
Adt Feb-10 Aug-12 Medtronic
Sen
Neuromodulation
Europe
170
Adt Feb-12 Aug-12 Light and Health http://ClinicalTrials.gov/show/NCT01528332
Venture
24
Adt Nov-08 Jul-12 BioSurface
Sen
Engineering
Technologies,
Inc
300
Adt
Sen
Jul-12 NuVasive
Not yet 200 Child Jan-10 Jun-12 Prince of
Rec
Adt
Songkla
University
Rec
Invite
Jul-09
100 Child May-11 Apr-12 Nationwide
Adt
Children's
Hospital
45
Wallis Mechanical Normalization Device: Interspinous Low Back Pain
System for Low Back Pain
process and dynamic
stabilization; Device:
study
Conservative Care
NCT00134537
Masimo Radical-7 Monitor a Useful Device: Masimo
Major Spine Surgery
Adjuvant During Major Spine
Radical-7
Procedure
Surgery
Prospective study
NCT01221961
MiDAS II (Mild® Decompression Device: mild®
Lumbar Spinal
Alternative to Open Surgery):
Interlaminar
Stenosis
Vertos Mild Patient Evaluation
Decompression
Study
assignment
NCT01082159
Safety and Efficacy of MRgFUS for Device: Exablate
Lower Back Pain,
the Treatment of Low Back Pain treatment
Facets Joints
Phase II: Single group
Osteoarthritis
study
NCT01232582
MiDAS I (Mild® Decompression
Device: MILD®
Lumbar Spinal
Alternative to Open Surgery):
Interlaminar
Stenosis
Vertos Mild Patient Evaluation
Decompression
Study
assignment
NCT00956631
Ultrasound as Adjunct Therapy for Device: Exogen
Lumbar
Increasing Fusion Success After Bone Healing
Degenerative Disc
Lumbar Surgery
System; Device:
Disease
Exogen Bone
study
Healing System
NCT00744861
Clinical Trial to Evaluate Safety
Device: Hyalospine Degenerative Spinal
and Efficacy of Hyalospine® in
Stenosis; Disk
Lumbar Laminectomy or
Herniation
Laminotomy
study
NCT00939406
Active,
NR
300
Adt Nov-04 Apr-12 Zimmer Spine;
Zimmer, Inc.
Rec
100
Adt Oct-10 Apr-12 Cedars-Sinai
Sen
Medical Center;
Masimo
Corporation
Active,
NR
55
Adt Feb-10 Apr-12 Vertos Medical, http://ClinicalTrials.gov/show/NCT01082159
Sen
Inc.
Comp
50
Adt Oct-09 Feb-12 InSightec
Sen
Active,
NR
78
Adt
Sen
Rec
400
Adt Sep-08 Dec-11 Smith &
Sen
Nephew, Inc.
Rec
50
Adt Nov-09 Dec-11 AO Clinical
Sen
Investigation and
Documentation
46
Jul-08 Jan-12 Vertos Medical, http://ClinicalTrials.gov/show/NCT00956631
Inc.
A Study of the In-Space Device for
Treatment of Moderate Spinal
Stenosis
study
NCT00697827
Comparison Between Return and
Wastage of Your Own Blood,
Collected During Spinal Surgery,
for Verification of Safety When
Returning Blood
RCT, safety study;
NCT01251042
Safety and Effectiveness Study of
Prodisc to Spinal Fusion Surgery
NCT00295009
Spine Research With Roentgen
Stereophotogrammetric Analysis
NCT00493558
Effects of X-STOP® Versus
Laminectomy Study
study
NCT00558129
Predicting Outcome of
Transcutaneous Electrical Nerve
Stimulator (TENS) in Failed Back
Surgery Syndrome
NCT01185665
Device: Interspinous Spinal Stenosis
Spacer device;
Device: Interspinous
Process Distraction
Device
Active,
NR
500
Adt Jun-08 Dec-11 Synthes USA
Sen
HQ, Inc.
Device: Sangvia
Spinal Surgery
Comp
51
Adt Oct-10 Dec-11 Astra Tech AB
Sen
Device: Total disc
replacement
Spinal Diseases
Active,
NR
510
Adt Sep-01 Dec-11 Synthes USA
HQ, Inc.
Active,
NR
25
Adt
Sen
Wdrwn
0
Adt Nov-07 Nov-11 Medtronic Spine http://ClinicalTrials.gov/show/NCT00558129
Sen
LLC
Device: TENS;
Failed Back Surgery Not yet
Device: Sham-TENS Syndrome
Rec
40
Adt Sep-10 Sep-11 Universitair
Sen
Ziekenhuis
Brussel;
Evenepoel
Kristof; De
Rudder Marc;
Dokter Moens
Maarten
(primary
investigator);
Prof. dr.
Cattrysse Eric;
Prof. Dr.
D'Haens Jean
Device: Trabecular Spondylolisthesis;
Metal Intervertebral Degeneration of
Cage with Roentgen Lumbar
Stereophotogrammet Intervertebral Disc;
ric Analysis beads
Spinal Stenosis
Device: X-STOP®; Lumbar Spinal
Procedure:
Stenosis
Laminectomy
47
Jul-07 Dec-11 Capital District http://ClinicalTrials.gov/show/NCT00493558
Health Authority,
Canada;
Zimmer, Inc.
GO-LIF With Percutaneous Facet
Fusion
NCT01269398
Pilot Study to Evaluate Feasibility
of DensiProbe Spine Assessing
Bone Strength in Spinal Surgery
NCT01126385
Device: GO-LIF and Lumbar Fusion
SpineAssist
SYSTEMS
Safety and Efficacy Study
Comparing ProDisc-C to ACDF
Surgery to Treat SCDD
NCT00291018
Study of Epidural Steroid Injection
(ESI) Versus Minimally Invasive
Lumbar Decompression (MILD®)
in Patients With Symptomatic
Lumbar Central Canal Stenosis
study
NCT00995371
Outcome Study of Patients
Treated With Translational
Cervical Plate Used to Treat
Degenerative Disc Disease
assignment
NCT00443547
TissueLink Study During MultiLevel Spine Surgery
NCT01300559
Clinical Outcomes of Lumbar
Degenerative Disc Disease in
Active-Duty U.S. Service
Personnel
NCT01028300
Device: Total Disc
Replacement
Device: MILD®
(Minimally Invasive
Lumbar
Decompression);
Drug: Epidural
Steroid Injection
Device: DensiProbe Spinal Diseases
Spine
Not yet N/K
Rec
Adt
Sen
N/K
Aug-11
Hadassah
Medical
Organization
Adt Aug-10 Jul-11 AO Clinical
Sen
Investigation and
Documentation;
University
Hospital
Inselspital,
Berne
Adt
N/K Jul-11 Synthes USA
HQ, Inc.
Rec
30
Diskectomy; Spinal
Fusion; Prostheses
and Implants
Active,
NR
228
Lumbar Spinal
Stenosis
Active,
NR
40
Adt Aug-09 Jun-11 Coastal
Sen
Orthopedics &
Sports Medicine;
Vertos Medical,
Inc.
Device: Anterior
Degenerative Disc
Cervical Discectomy Disease
and Fusion (ACDF)
Comp
231
Adt Mar-06 Apr-11 Synthes USA
Sen
HQ, Inc.
Device: Tissuelink
device
Active,
NR
60
Adt Apr-06 Apr-11 Duke University; http://ClinicalTrials.gov/show/NCT01300559
Sen
Salient Surgical
Technologies
Term
4
Adt
Low Back Pain
Device: ProDisc™-L Degenerative Disc
Total Disc
Disease
Replacement (TDR)
48
Apr-10 Mar-11 Synthes USA
HQ, Inc.
Lumbar Degenerative Disc
Disease Treated With Anterior
Tension Band System (ATB) With
ALIF/FRA Spacer
NCT01323387
Surgical Outcomes Using Variable
Rod Diameters in the Treatment of
study
NCT00510575
Device to Reduce Surgery Site
Contamination - Spine
NCT01262105
Spine Fusion Instrumented With
BMP-2 vs Uninstrumented With
Infuse BMP-2 Alone
NCT00405600
Assessment of Low Level Laser
Therapy for Late Postoperative
Pain After Lumbar Fusion Surgery
RCT
NCT00422045
Evaluation of the PediGuard™ for
Pedicle Screw Insertion
RCT
NCT00549627
Dynamic Stabilization for Lumbar
Spinal Stenosis With Stabilimax
NZ® Dynamic Spine Stabilization
System
NCT00529997
Comparison of Cervical
Laminectomy to Laminoplasty
RCT
NCT01324622
Device: Interbody
Fusion
Lumbar
Degenerative Disc
Disease
Comp
150
Device: Spinal rod
Scoliosis
Comp
300 Child May-07 Jan-11 Shriners
Adt
Hospitals for
Children
Device: Air Barrier
System Device
Surgery
Comp
23
Child Nov-09 Dec-10 Nimbic Systems, http://ClinicalTrials.gov/show/NCT01262105
Adt
LLC
Sen
Device: Infuse Bone Degenerative
Graft BMP-2, Large Lumbar Disc
Kit
Disease;
Spondylolisthesis;
Spinal Stenosis
Device: Low Level
Surgery
Laser Therapy
Comp
50
Adt Nov-06 Dec-10 Capital District http://ClinicalTrials.gov/show/NCT00405600
Sen
Health Authority,
Canada
Comp
50
Adt Dec-06 Dec-10 University of
Sen
Toledo Health
Science Campus
Device: Pediguard
Susp
108 Child Aug-05 Dec-10 Shriners
Adt
Hospitals for
Sen
Children
Device: Stabilimax Lumbar Spinal
NZ® Dynamic Spine Stenosis
Stabilization System
Term
480
Adt Feb-07 Dec-10 Applied Spine
Sen
Technologies
Device: Laminoplasty Spinal Cord
(ARCH Fixation
Diseases
System); Procedure:
laminectomy
Term
24
Adt Jan-06 Nov-10 Synthes USA
Sen
HQ, Inc.
Posterior Spinal
Fusion
49
Adt Apr-04 Feb-11 Synthes USA
Sen
HQ, Inc.
MAVERICK™ Total Disc
Replacement- Pivotal Study
study
NCT00635843
Device:
Spinal Diseases
MAVERICK™ Disc;
Device: LT-CAGE®
Lumbar Tapered
Fusion Device and
INFUSE® Bone Graft
Device: rhBMPDegenerative Disc
2/CRM/CD
Disease
HORIZON® Spinal
System
rhBMP-2/CRM/CD HORIZON®
Spinal System Pilot Study (2Level)
NCT01491568
Comprehensive Cohort Study of Device: Brace
Bracing for Adolescent Idiopathic
Scoliosis (AIS): A Feasibility Study
NCT00989495
A Post-Market Study of Transfacet Device: PERPOS™
Lumbar Spine Fixation and Fusion PLS
Utilizing the PERPOS™ PLS
System
efficacy study
NCT00887835
Activ-L™ Artificial Disc Treatment Device: Activ-L
of Degenerative Disc Disease in Artificial Disc;
the Treatment of Degenerative
Device: ProDisc
Disc Disease
Total Disc
Replacement or
study
Charite Atifical Disc
NCT00589797
Is Pleth Variability Index (PVI) a
Device: Masimo
Surrogate for Pulse Pressure
multi-wavelength
Variations (PPV) in Pediatric Spine pulse co-oximeter
Fusion (SF) Surgery?
NCT00994656
Safety and Performance Study of Device: CAdisc™-L
the CAdiscTM-L Lumbar Spinal
(Total Disc
Disc Replacement Device For CE Replacement)
Marking
NCT00949936
Comp
577
Adt Apr-03 Nov-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00635843
Sen
and Biologics
Comp
29
Adt
Sen
Active,
NR
40
Lumbar Facet
Disease
Child Oct-08 Oct-10 The University of http://ClinicalTrials.gov/show/NCT00989495
Adt
Hong Kong;
Sen
Scoliosis
Research
Society
Not yet 100 Adt Apr-09 Oct-10 Interventional
Rec
Sen
Spine, Inc.
Degenerative Disc
Disease
Active,
NR
414
Scoliosis; Spinal
Fusion
Comp
24
Chronic Low Back
Pain; Lumbar
Degenerative Disc
Disease
Comp
Adolescent
Adt
Jul-05 Nov-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01491568
and Biologics
Jan-07 Jul-10 Aesculap
Implant Systems
Child Oct-09 Jul-10 Children's
Adt
Hospital of
Philadelphia;
Children's
Anesthesiology
Associates, Ltd.
N/K Adt Oct-09 Jun-10 Ranier
Technology
Limited
50
Percutaneous Dynamic
Device: PDS
Lumbar
Stabilization (PDS) System Versus System; Device:
Degenerative Disc
Fusion for Treating Degenerative Fusion
Disease
Disc Disease
study
NCT00878579
Long-Term Outcomes for Lumbar Device: X STOP®
Lumbar Spinal
Spinal Stenosis Patients Treated Interspinous Process Stenosis
With X STOP®
Decompression
Phase IV: Cohort study
System
NCT00534092
A-MAV™ Anterior Motion Segment Device: A-MAV™
Spinal Diseases
Replacement
disc
study
NCT00635934
Phase IV Comparing Rods of Yield Device: titanium rod; Scoliosis
Strengths to Correct Adolescent
Device: ultra strength
Idiopathic Scoliosis.
stainless steel rod
NCT00768313
Intermittent Neurogenic
Device: Aperius®
Spinal Stenosis
Claudication Treatment With
Percutaneous
APERIUS®
Interspinous Spacer
study
NCT00887744
A Pilot Study to Evaluate an OP-1 Device: TLIF with a Degenerative Disc
Putty Spinal System and an
PEEK Spacer
Disease
Autograft Spinal System
System and XIA
RCT, efficacy study
Spinal System
NCT00678171
rhBMP-2/CRM/CD HORIZON®
Device: rhBMPDegenerative Disc
Spinal System Pivotal Study
2/CRM/CD
Disease
HORIZON® Spinal
study
System; Device:
NCT00707265
Autograft/CD
HORIZON® Spinal
System
Rec
292
Adt Mar-09 Jun-10 Interventional
Sen
Spine, Inc.
Comp
69
Adt Dec-06 Jun-10 Medtronic Spine http://ClinicalTrials.gov/show/NCT00534092
Sen
LLC
Comp
53
Adt Dec-05 May-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00635934
Sen
and Biologics
Term
0
Comp
Child Sep-08 Apr-10 Queen's
Adt
University;
Johnson &
Johnson; DePuy
Orthopaedics
162 Adt Nov-06 Mar-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00887744
Sen
& Biologics ECA
Comp
30
Adt Feb-07 Mar-10 Olympus Biotech http://ClinicalTrials.gov/show/NCT00678171
Sen
Corporation
Comp
463
Adt Mar-02 Feb-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00707265
Sen
and Biologics
51
the TOPS System, a Total
Posterior Arthroplasty Implant
Designed to Alleviate Pain
Resulting From Moderate to
Severe Lumbar Stenosis
study
NCT00405691
Healos as a Bone Replacement to
Treat Degenerative Disc Disease
study
NCT00316121
Dietary supplements
Bone Mineral Density in
Postmenopausal Women With
Primary Breast Cancer Who Are
Receiving Treatment on Clinical
Trial CAN-NCIC-MA27
assignment
NCT00354302
Dexamethasone Versus Depo
Medrol in Lumbar Epidurals
RCT, efficacy study
NCT01397552
Device: “TOPS
System” - Total
Posterior
Arthroplasty Implant"
Comp
450
Adt Sep-06 Jan-10 Impliant, Ltd.
Sen
Device: HEALOS
Degenerative Disc
and Leopard Cage; Disease
Device: Leopard
Cage and Autograft
Comp
138
Adt Apr-06 Jan-10 Advanced
Sen
Technologies
and
Regenerative
Medicine, LLC
(ATRM); DePuy
Spine
Dietary Supplement: Breast Cancer;
calcium carbonate; Osteoporosis
Dietary Supplement:
calcium citrate;
Dietary Supplement:
cholecalciferol; Drug:
alendronate sodium;
Drug: calcium
gluconate; Drug:
risedronate sodium;
Other: laboratory
biomarker analysis;
Procedure: dual xray absorptometry
Comp
497
Adt Apr-06 Mar-11 NCIC Clinical
Sen
Trials Group;
National Cancer
FInstitute (NCI);
only
North Central
Cancer
Treatment
Group;
Southwest
Oncology Group
Drug:
Dexamethasone;
Drug:
methylprednisolone
acetate
Invite
100
Adt Sep-09 Dec-15 State University http://ClinicalTrials.gov/show/NCT01397552
Sen
of New York Upstate Medical
University
Low Back Pain; Leg
Pain;
Spondylolisthesis;
Lumbar Spinal
Stenosis
Lumbar Spine Disc
Herniation; Lumbar
Radiculitis; Lumbar
Back Pain
52
The Effect of Prolonged
Postoperative Antibiotics
Administration on Rate of Infection
in Patients Undergoing Posterior
Spine Surgery Requiring a
Hemovac Drain
NCT01458223
Study of Mesenchymal Precursor
Cells (MPCs) in Subjects With
Chronic Discogenic Lumbar Back
Pain
study
NCT01290367
Drug: Antibiotic;
Drug: Antibiotic
Postoperative
Infection
Rec
600 Child Oct-11 Oct-15 The London
Adt
Spine Centre
Sen
Biological: Single
Dose MPCs
Injection; Biological:
Single Dose MPCs
Injection; Procedure:
Single injection of
saline solution;
Procedure: Single
injection of
hyaluronic acid
Biological:
teriparatide
Degenerative Disc
Disease
Rec
100
Adt Aug-11 Jul-15 Mesoblast, Ltd.
Sen
Lumbar Spondylosis;
Lumbar
Spondylolisthesis;
Adult Degenerative
Lumbar Scoliosis
Postoperative Pain;
spine, hip or knee
replacement.
Rec
90
Rec
312
Adt Aug-11 Nov-14 University of
Sen
California, San
Francisco; Eli
Lilly and
Company
Adt Aug-05 Sep-14 University of
Sen
California, San
Francisco
Back Pain; Chronic
Low Back Pain;
Internal Disc
Disruption;
Degenerative Disc
Disease
Back Pain
Rec
260
Adt Mar-10 Jun-14 Spinal
Sen
Restoration, Inc.
Susp
100
Adt Jan-12 Mar-14 University of
Sen
Alabama at
Birmingham
Use of Forteo (Teriparatide) in
Posterolateral Lumbar Spine
Fusion
RCT, efficacy study
NCT01292252
Clinical Trial of Gabapentin to
Drug: Gabapentin
Improve Postoperative Pain in
Surgical Patients
study
NCT00221338
Treatment of Symptomatic Lumbar Biological: Biostat
Internal Disc Disruption (IDD) With System; Drug:
the Biostat® System
Sodium Chloride
Injection
study
NCT01011816
Analgesic Efficacy of Intravenous Drug: Lidocaine
Lidocaine for Postoperative Pain Hydrochoride
Following Adult Spine Surgery
Injection, without
RCT, efficacy study
epinephrine; Drug:
NCT01043211
Normal Saline; Drug:
Normal Saline
53
Evaluation of the Effectiveness of
Transforaminal Epidural Injections
in Lumbar Disc Herniation or
Radiculitis
NCT01052571
A Study of Oxycodone/Naloxone
Controlled-release Tablets (OXN)
to Assess the Analgesic Efficacy
and the Management of Opioidinduced Constipation (OIC) in
Opioid-experienced Subjects With
Controlled Moderate to Severe
Chronic Low Back Pain
NCT01427283
Umbilical Cord/Placenta-Derived
Mesenchymal Stem Cells to Treat
Ankylosing Spondylitis (AS)
study
NCT01420432
Analgesic Efficacy and
Management of Opioid-induced
Constipation (OIC) for
Uncontrolled Moderate - Severe
Low Back Pain
NCT01427270
Work Productivity in Active
Ankylosing Spondylitis (AS)
Patients Treated With Enbrel.
study
NCT01421303
Comparison of Two Naloxone
Infusion Rates on the
Postoperative Recovery of
Patients Undergoing Spine Fusion
Surgery
RCT, efficacy study
NCT01531439
Drug: lumbar
transforaminal
epidural injections
Low Back Pain
Invite
120
Adt Feb-10 Jan-14 Pain
Sen
Management
Center of
Paducah
Drug:
Low Back Pain
Oxycodone/Naloxon
e controlled-release;
Drug: Oxycodone
HCl controlledrelease; Drug:
Placebo
Rec
900
Adt Aug-11 Jan-14 Purdue Pharma http://ClinicalTrials.gov/show/NCT01427283
Sen
LP
Biological: Human
umbilical cordderived MSCs
Rec
10
Adt
Rec
900
Adt Aug-11 Dec-13 Purdue Pharma http://ClinicalTrials.gov/show/NCT01427270
Sen
LP
Active,
NR
120
Adt Nov-09 Nov-13 Pfizer
Sen
Rec
80
Child Jun-11 Sep-13 Children's Mercy http://ClinicalTrials.gov/show/NCT01531439
Adt
Hospital Kansas
City
Ankylosing
Spondylitis
Drug: Oxycodone/
Low Back Pain
Naloxone controlledrelease; Drug:
Oxycodone HCl
controlled-release;
Drug: Placebo
Drug: Enbrel
Ankylosing
Spondylitis
Drug: Naloxone;
Drug: Naloxone
Pain, Postoperative;
Postoperative
Nausea and
Vomiting; Scoliosis
54
Jan-11 Dec-13 Shandong
University
Comparison of Three Methods of
Hemoglobin Monitoring
NCT01284296
Phase 3 Study of Fibrocaps™ in
Surgical Bleeding
NCT01527357
Drug: Lidocaine
digital block
Digital Block; spinal
surgery
Active,
NR
20
Adt Aug-10 Aug-13 University of
Sen
California, San
Francisco
Biological: Fibrocaps; Mild or Moderate
Not yet 500 Adt May-12
Device: Gelatin
Surgical Bleeding;
Rec
Sen
spine, liver, vascular
sponge
or soft tissue
surgery.
Efficacy of Pregabalin in Patients Drug: Pregabalin;
Lumbar Radicular
Rec
38
Adt May-09
With Radicular Pain
Drug: Sugar Pill
Pain; Failed Back
Surgery Syndrome;
NCT00908375
Spinal Stenosis;
Herniated Disc
A Multicenter, Randomized,
Drug: Intradiscal
Degenerative Disc
Active, 30
Adt Jan-10
Double-blind, Placebo Controlled, rhGDF-5; Other:
Disease
NR
Sen
Clinical Trial to Evaluate the
Water for injection
Safety, Tolerability and Preliminary
Effectiveness of 2 Doses of
Intradiscal rhGDF-5 (Single
Administration) for the Treatment
of Early Stage Lumbar Disc
Degeneration
study
NCT01124006
Anesthesia During
Drug: propofol; Drug: Idiopathic Scoliosis
Invite
20 Child Jan-12
Neurophysiologic Monitoring in
Desflurane
Adt
Scoliosis Patients
Sen
RCT, efficacy study
NCT01549873
Methadone Versus Placebo in
Drug: Methadone;
Postoperative Pain
Invite
80
Adt May-10
Spine Fusion
Drug: Saline
Sen
NCT01125059
Safety and Efficacy of DepoDur in Drug: DepoDur
Lumbar Spine Surgery Patients
NCT00335517
Lumbar Spine
Surgery
Active,
NR
98
55
May-13 ProFibrix, Inc.
May-13 Northwestern
University
Apr-13 Advanced
Technologies
and
Regenerative
Medicine, LLC
(ATRM); DePuy
Spine
Jan-13 Nationwide
Children's
Hospital
Dec-12 Northwestern
University;
Feinberg School
of Medicine,
Northwestern
University
Adt Jun-06 Nov-12 University of
Sen
Rochester; EKR
Therapeutics,
Inc
Study Evaluating The Use Of
Drug: Etanercept
Etanercept In Patients With
Ankylosing Spondylitis
NCT00544557
Osteocel® Plus in Anterior
Biological: Biologic Cervical Discectomy and Fusion Osteocel Plus
(ACDF)
NCT00942045
Osteocel® Plus in eXtreme Lateral Biological: biologic,
Interbody Fusion (XLIF®)
Osteocel Plus
efficacy study
NCT00948532
Osteocel® Plus in Anterior Lumbar Biological: Osteocel
Interbody Fusion (ALIF)
Plus
NCT00948831
Radiographic Analysis Using
Biological: PureGen
PureGen Versus Autologous Bone Osteoprogenitor Cell
in Posterolateral Fusion (PLF)
Allograft; Procedure:
RCT
Autograft bone
NCT01294007
Efficacy and Safety of
Drug:
Oxycodone/Naloxone Controlled- Oxycodone/Naloxon
release Tablets (OXN) Compared e Controlled-release;
to Placebo in Opioid-experienced Drug: Placebo
Subjects With Moderate to Severe
Chronic Low Back Pain
study
NCT01358526
Impact of Tranexamic Acid on Red Drug: Tranexamic
Blood Cell Transfusion in Spinal
Acid; Drug: Placebo
Surgery
NCT01258010
Ankylosing
Spondylitis
Rec
1800 Adt Nov-07 Oct-12 Pfizer
Sen
Degenerative Disc
Disease in Cervical
Spine
Active,
NR
175
Adt Feb-09 Aug-12 NuVasive
Sen
Degenerative Disc
Disease; Back Pain
Active,
NR
150
Adt Mar-09 Aug-12 NuVasive
Sen
Degenerative Disc
Disease, Lumbar
Active,
NR
70
Adt Apr-09 Aug-12 NuVasive
Sen
Lumbar
Degenerative Disc
Disease
Rec
50
Adt Feb-11 Aug-12 Alphatec Spine, http://ClinicalTrials.gov/show/NCT01294007
Sen
Inc.
Low Back Pain
Rec
600
Adt May-11 Aug-12 Purdue Pharma http://ClinicalTrials.gov/show/NCT01358526
Sen
LP
Neurosurgery;
Orthopedic Surgery;
Red Blood Cell
Transfusion
Rec
128
Adt Apr-11 Aug-12 Centre
Sen
hospitalier de
l'Université de
Montréal
(CHUM)
56
Pain Relief at Iliac Crest Bone
Harvest Sites in Spine Surgery
Using Bupivacaine
RCT, efficacy study
NCT01087931
The Use of Intrathecal Morphine in
the Management of Acute Pain
Following Decompressive Lumbar
Spinal Surgery
NCT01053039
Multicenter, Randomized Placebocontrolled Clinical Trial to Evaluate
the Effect of Perioperative Use of
Tranexamic Acid on Transfusion
Requirements and Surgical
Bleeding in Major Spine Surgery
NCT01136590
Drug: Bupivacaine; Pain
Other: Normal Saline
Rec
100
Drug: Intrathecal
Morphine; Drug:
Intrathecal Saline
Rec
150 Child Jan-10 Jul-12 University of
Adt
Calgary
Sen
Drug: Tranexamic
Spinal Fusion;
Acid; Drug: fisiologic Antifibrinolytic
serum
Agents;
Hemorrhage; Blood
Transfusion
Rec
130
Osteocel® Plus in Posterior
Lumbar Interbody Fusion (PLIF)
NCT00941980
Analgesic Efficacy of Repeated
Doses of Intravenous (IV)
Acetaminophen in Post-operative
Pediatric Spine Fusion Patients
NCT01394718
Osteocel® Plus in Transforaminal
Lumbar Interbody Fusion (TLIF)
NCT00947583
Biological: Osteocel Degenerative Disc
Plus
Disease
Active,
NR
70
Drug: Intravenous
Acetaminophen
Acute Pain Following
Decompressive
Lumbar Spinal
Surgery
Pain, Postoperative
Biological: Osteocel Degenerative Disc
Plus
Disease
Rec
60
Active,
NR
50
57
Adt Apr-10 Jul-12 Vanderbilt
Sen
University
Adt Sep-10 Jul-12 Hospital
Sen
Universitari Vall
d'Hebron
Research
Institute;
Hospital Vall
d'Hebron;
Hospital Clinic of
Barcelona;
Hospital
Universitari de
Bellvitge;
Hospital de
Getafe.
Jun-12
Adt Jun-09
NuVasive
Sen
Fonly
Child Jul-11 Jun-12 Children's
Adt
Hospital of
Philadelphia
Adt May-09 May-12 NuVasive
Sen
Perioperative Pain Management In Drug: 150% Oral
Pain
Spine Surgery Patients: Part I
Morphine Equivalent
RCT, efficacy study
(OME); Other:
NCT01447888
Clinical Judgment
Rec
200
Effect of Ketamine Added to
Drug: Ketamine;
Intravenous Patient-controlled
Drug: Saline
Analgesia on Postoperative Pain,
Nausea and Vomiting in Patients
Undergoing Lumbar Spinal
Surgery
NCT01394406
Perioperative Intravenous
Drug: Lidocaine;
Lidocaine or Epidural Anesthesia Other: placebo;
on Outcomes in Complex Spine
Other: Morphine
Surgery
sulfate
NCT00840996
The Effect of Zoledronic Acid to
Drug: zoledronic
Bone Fusion and Bone Metabolism acid; Drug: sodium
of Patients With Lumbar
chloride
Degenerative Disease After
Lumbar Interbody Fusion
NCT01310465
The Effect of Intravenous
Drug: Intravenous
Lidocaine on Pain After Lumbar
lidocaine injection;
Spinal Fusion
Drug: Intravenous
normal saline
NCT01319682
injection
Intradiscal rhGDF-5 Phase I/II
Drug: Intradiscal
Clinical Trial
rhGDF-5
study
NCT00813813
Postoperative
Nausea and
Vomiting
Rec
50
Spine Surgery;
Intraocular Pressure
Rec
Image Changes of
Lumbar Fusion;
Bone Turnover
Markers; Bone
Mineral Density
Low Dose Ketamine Study on
Opioid Tolerance and
Hyperalgesia
NCT01325493
Adt Sep-11 May-12 Abbott
Sen
Northwestern
Hospital; Allina
Hospitals and
Clinics
Adt Jan-10 May-12 Yonsei
University
200
Adt May-08 May-12 Outcomes
Sen
Research
Consortium
Rec
50
Adt Jan-11 Apr-12 Fudan University http://ClinicalTrials.gov/show/NCT01310465
Sen
Postoperative Pain
Not yet
Rec
54
Adt Mar-11 Feb-12 Chung-Ang
Sen
Univerisity
Hospital
Degenerative Disc
Disease
Active,
NR
48
Rec
50
Adt Jun-08 Jan-12 Advanced
Sen
Technologies
and
Regenerative
Medicine, LLC
(ATRM); DePuy
Spine
Child Jan-10 Jan-12 Children's
Adt
Research
Institute
Drug: Ketamine;
Idiopathic Scoliosis;
Drug: Normal Saline Spondylolisthesis
58
Pregabalin for the Treatment of
Drug: Pregabalin 150 Lumbar Spinal
Pain After Posterior Spinal Fusions mg; Drug: Placebo Fusions
study
NCT01366196
Intraoperative Infusion of Precedex Drug: Intravenous
Spinal Fusion
to Reduce Length of Stay After
infusion of
Acquired; Spinal
Lumbar Spine Fusion
Dexmedetomidine or Stenosis; Lesion of
Phase IV: RCT,
0.9% Saline
Lumbosacral
pharmacodynamics study
Intervertebral Disc;
NCT00808665
Spinal Diseases
The Effect of Perioperative
Drug: Placebo; Drug: Postoperative Pain
Ketamine on Acute and Chronic
Ketamine
Pain After Major Back Surgery
study
NCT00618423
Extension Study for Long Term
Drug: SAR153191
Ankylosing
Evaluation of SAR153191
(REGN 88)
Spondylitis
(REGN88) in Patients With
NCT01118728
The Analgesic Effect of Combined Drug: s-ketamine & Analgesia, PatientTreatment With Intranasal Smidazolam; Drug:
controlled; Spinal
ketamine and Intranasal
Morphine PCA
Stenosis
Midazolam
study
NCT01275547
A Clinical Trial to Study the Effects Drug: Eperisone
Acute
of a Fixed Dose Combination of
hydrochloride and
Musculoskeletal
Diclofenac and Eperisone
Diclofenac sodium; Spasm Due to Low
Hydrochloride With Plain
Drug: Eperisone
Back Pain
Eperisone Hydrochloride in
hydrochloride
Patients With Low Back Pain
study
NCT01300312
Rec
80
Adt Oct-08 Jan-12 Hospital for
Sen
Special Surgery,
New York; Pfizer
Rec
60
Adt Jun-09 Dec-11 Vanderbilt
Sen
University
Rec
180
Adt Oct-07 Dec-11 University
Sen
Hospital,
Geneva
Term
223
Adt Jun-10 Dec-11 Sanofi-Aventis; http://ClinicalTrials.gov/show/NCT01118728
Sen
Regeneron
Pharmaceuticals
Rec
36
Adt Jan-11 Dec-11 University
Sen
Hospital, Basel,
Switzerland
Rec
240
Adt Feb-11 Nov-11 Eisai Co., Ltd.
59
Radiographic and Clinical
Biological: PureGen Lumbar
Rec
Outcomes of PureGen in Posterior Osteoprogenitor Cell Degenerative Disc
Lumbar (PLIF) and Transforaminal Allograft
Disease
Interbody Fusion (TLIF)
NCT01293981
Intraarticular Lumbar Joint
Drug: Intra-articular Low Back Pain
Rec
Corticosteroid Injection(s) as a
corticosteroid
Treatment of Chronic Low Back
injection; Drug: IntraPain in a Selected Population
articular saline
injection
NCT01382771
The Optimal Effect Site
Drug: propofol
Conscious Sedation
Rec
Concentration of Propofol for
Under Spinal
Conscious Sedation in Elderly
Anesthesia
Male Patients Undergoing Urologic
Surgery Under Spinal Anesthesia
With or Without Intrathecal
Fentanyl
RCT, efficacy study
NCT01232270
Study of Whether 15 mg Dose of Drug: Ketorolac
Pain; Pain,
Rec
Ketorolac IV is as Effective as a 30 Tromethamine; Drug: Postoperative; spinal
surgery
mg Dose.
Ketorolac
RCT, efficacy study
Tromethamine
NCT01230463
Memantine for Post-Operative
Drug: Memantine;
Pain, Post-operative; Rec
THR; TKR; lumbar
Pain Control
Drug: Placebo
spinal fusion
study
NCT01041313
Study to Evaluate the Efficacy and Drug: Hydrocodone; Pain
Comp
Safety of Hydrocodone Bitartrate Drug: Placebo
Extended-Release Tablets (CEP33237) for Relief of Moderate to
Severe Pain in Patients With
Osteoarthritis or Low Back Pain
Who Require Opioid Treatment for
an Extended Period of Time
Phase III: RCT
NCT01240863
150
Adt Feb-11 Oct-11 Alphatec Spine, http://ClinicalTrials.gov/show/NCT01293981
Sen
Inc.
120
Adt Oct-10 Oct-11 University of
Sen
Florida
50
Adt Oct-10 Oct-11 Yonsei
Sen
University
Monly
50
Adt Sep-10 Sep-11 University of
Calgary
120
Adt Jan-10 Sep-11 University of
Sen
Washington;
Forest
Laboratories
391
Adt Nov-10 Aug-11 Cephalon
Sen
60
Clinical Trial to Assess Safety of
SI-6603 in Patients With Lumbar
Disc Herniation
study
NCT01282606
The Bupivacaine Dose Sparing
Effect of Intrathecal Epinephrine
NCT01261078
Drug: SI-6603
Lumbar Vertebra
Hernia
Drug: Placebo; Drug: Spinal Anesthesia
epinephrine 25;
Drug: Epinephrine
50; Drug:
epinephrine 100;
Drug: Epi 200
Dose Ranging Study to Evaluate Drug: SAR153191
Ankylosing
the Efficacy and Safety of
(REGN88); Drug:
Spondylitis
SAR153191 (REGN88) in Patients placebo
With Ankylosing Spondylitis
NCT01061723
A Preemptive Epidural
Drug: Placebo (one Postoperative Pain
Ropivacaine for Postoperative
of medication); Drug:
Pain Relief in Degenerative
Ropivacaine
Lumbar Spine Surgery
(epidural injection)
NCT01117610
The Effect of Pregabalin and
Drug: Pregabalin;
Pain
Dexamethasone on Acute and
Drug:
Chronic Pain After Lumbar Spinal dexamethasone;
Surgery
Drug: placebo
NCT01168531
Efficacy of Ropivacaine
Drug: Ropivacaine Postoperative Pain
Continuous Wound Instillation
Versus Single Shot After Spine
Fusion Surgery
NCT00823576
Continuous Local Infusion of
Drug: Bupivacaine; Scoliosis
Anesthetic at the Incisional Site for Drug: Normal Saline
Scoliosis Surgery
study
NCT00508066
Active,
NR
18
Adt Dec-07 Aug-11 Seikagaku
Sen
Corporation
Comp
75
Adt Dec-10 Jul-11 Seoul Medical
Sen
Center
Comp
300
Adt Feb-10 Jun-11 Sanofi-Aventis; http://ClinicalTrials.gov/show/NCT01061723
Sen
Regeneron
Pharmaceuticals
Not yet
Rec
60
Adt May-10 Apr-11 Chung-Ang
Univerisity
Hospital
Comp
108
Adt Dec-09 Mar-11 Yonsei
Sen
University
Term
64
Adt Dec-08 Mar-11 Centre
Sen
Hospitalier
Universitaire de
Nice
Comp
60
Child May-07 Jan-11 Shriners
Adt
Hospitals for
Children
61
The Effect of Magnesium Sulfate Drug: Magnesium
Scoliosis
on Motor and Somatosensory
Evoked Potentials in Children
Undergoing Scoliosis Surgery
Phase II: RCT, efficacy study;
NCT01148888
Tranexamic Acid (TXA) Versus
Drug: Tranexamic
Scoliosis
Epsilon Aminocaproic Acid (EACA) Acid; Drug: Normal
Versus Placebo for Spine Surgery Saline; Drug: Epsilon
aminocaproic acid
NCT00958581
Gabapentin for Prophylaxis
Drug: Gabapentin
Intrathecal
Intrathecal Morphine-Induced
Morphine; Spinal
Pruritus
Anesthesia;
Orthopedic Surgery
NCT01236859
Ephedrine vs Phenylephrine - ECG Drug: Phenylephrine; Spinal Anesthesia;
Changes
Drug: Ephedrine
Pregnancy
NCT01243970
The Darbepoetin Alfa for Ischemic Drug: Darbepoetin
Surgical Complications (DISC)
alfa
Dose Finding Trial
assignment
NCT00647998
IRB-HSR# 14145 R,S Methadone: Drug: methadone
Analgesia and Pharmacokinetics in
Adolescents Undergoing Scoliosis
Correction
Phase III: RCT,
pharmacokinetics study
NCT01205256
Local Anesthetic Infiltration to
Drug: Ropivacaine /
Prevent Postoperative Pain After Placebo
Lumbar Surgery
study
NCT00825422
Rec
15
Child Apr-10 Dec-10 The Hospital for http://ClinicalTrials.gov/show/NCT01148888
Adt
Sick Children
Rec
390 Child Dec-08 Dec-10 New York
Adt
University
Sen
Comp
180 Child Sep-09 Nov-10 Prince of
Adt
Songkla
Sen
University
Nov-10 University
College London
Hospitals;
Obstetric
FAnaesthetists'
only
Association
Sen
Pennsylvania
Not yet 220 Child
Rec
Adt
Sen
N/K
Spinal Ischemia;
Stroke;
Neuroprotection
Susp
40
Scoliosis
Invite
11
Child Mar-09 Sep-10 University of
Adt
Virginia
Hyperalgesia
Comp
50
Adt Jan-09 Aug-10 University
Sen
Hospital,
Bordeaux
62
SI-6603 Versus Placebo in
Patients With Lumbar Disc
Herniation
study
NCT00634946
Immunogenicity and Safety Study
of rThrombin in Surgical
Hemostasis
NCT00813904
Analgetic and Anxiolytic Effect of
Preoperative Pregabalin
NCT00353704
Influence of Dexmedetomidine on
the Evoked Potentials During
Spine Surgery
NCT00494832
Anesthesia Induction in Patients
Undergoing Surgery for Cervical
Myelopathy
study
NCT01052337
Post-operative Epidural Analgesia
After Minimally Invasive Lumbar
Decompression and Fusion
RCT
NCT00644111
Drug: SI-6603; Drug: Lumbar Vertebra
Placebo
Hernia
Comp
195
Adt Jan-08 Aug-10 Seikagaku
Sen
Corporation
Biological:
rThrombin, 1000
IU/mL
Blood Loss,
Surgical; spine,
arteriovenous graft
formation, or
peripheral artery
bypass surgical
procedure
Drug: pregabalin;
Intervertebral Disk
Drug: Placebo; Drug: Displacement; Disk
morphine
Prolapse
Comp
31
Adt Jan-09 Jul-10 ZymoGenetics
Sen
Comp
50
Adt Nov-05 Jun-10 Asker & Baerum http://ClinicalTrials.gov/show/NCT00353704
Sen
Hospital
Drug:
Spine Surgery
Dexmedetomidine;
Drug: Normal Saline
Active,
NR
40
Adt Feb-08 May-10 University of
Sen
Washington;
Hospira, Inc.
Drug: anaesthetics: Spinal Cord
sevofluorane
Diseases
Rec
116
Adt Apr-09 Mar-10 University of
Sen
Roma La
Sapienza
Drug: Bupivicaine,
Low Back Pain
Hydromorphone;
Drug: Saline Placebo
Rec
32
Adt Feb-08 Mar-10 University Health http://ClinicalTrials.gov/show/NCT00644111
Sen
Network,
Toronto
63
Effectiveness of Caudal Epidural
Injections in Treatment of Chronic
Low Back and Lower Extremity
Pain
NCT00370799
Efficacy of Gabapentin or
Amitriptyline to Reduce
Postoperative Pain After Lumbar
Laminectomy and Diskectomy
NCT01014520
The Effects of Potassium Citrate
on Bone Metabolism
NCT00357331
Procedure
'Acupuncture Therapy' for Pain
and Function Recovery in Spine
Surgery Patients
NCT01304979
Lumbar Disc Herniation Outcome
Measures
NCT01041391
Magnetic Resonance Imaging
(MRI) Interpretations for Lumbar
Spinal Stenosis (LSS)
NCT01017692
Drug: Caudal
epidural injection;
Drug: Caudal
Epidural Injection
with generic
Celestone; Drug:
Caudal Epidural
Injection with
Celestone; Drug:
Caudal Epidural
Injection with
DepoMedrol
Drug: Gabapentin ,
Amitriptyline
Low Back Pain
Active,
NR
240
Adt Jan-06 Mar-10 Pain
Sen
Management
Center of
Paducah
Drug: potassium
citrate
Herniated Disc;
Intervertebral Disc
Displacement
Rec
120
Adt May-09 Mar-10 Tabriz University http://ClinicalTrials.gov/show/NCT01014520
Bone Diseases,
Metabolic;
Osteoporosis,
Postmenopausal
Rec
75
Adt
Sen
Procedure:
Acupuncture
therapies;
Procedure: Control
Pain; Low Back
'Spine Fusion'
Surgery
Invite
114
Adt Sep-10 Nov-00 Beth Israel
Sen
Medical Center
Procedure:
Discectomy-lumbar
spine
Lumbar
Intervertebral Disc
Herniation
Invite
200
Procedure: MRI
Lumbar Spinal
Stenosis
Invite
100
Adt May-09 Dec-20 State University http://ClinicalTrials.gov/show/NCT01041391
Sen
University
Adt Jun-09 Dec-20 State University http://ClinicalTrials.gov/show/NCT01017692
Sen
University
Fonly
64
Jul-06 Dec-09 Weill Medical
College of
Cornell
University
Neurogenic Intermittent
Claudication Evaluation Study
NCT00905359
Procedure:
Aperius™ PercLID™
System and
Standalone
Decompressive
Surgery
Conservative Versus Aggressive Procedure:
Discectomy for Primary Disc
conservative
Herniation With Radiculopathy
discectomy;
Procedure:
NCT01204008
aggressive
discectomy
A Multicenter Prospective Study of Procedure: Surgical
Quality of Life in Adult Scoliosis
intervention; Other:
Non operative
NCT00854828
intervention
Surgery Versus Standardized Non- Procedure: Lumbar
operative Care for the Treatment Microdiscectomy;
of Lumbar Disc Herniations: A
Other:
Canadian Trial
Physiotherapy,
Phase III: RCT
Epidural injections,
NCT01335646
Education, Pain
Medications, Antiinflammatories
Spinal Stenosis
Rec
280
Adt Jan-10 Dec-15 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00905359
Sen
& Biologics ECA
Herniated Disc
Rec
100
Adt Sep-09 Dec-15 Sun Yat-sen
University
Scoliosis
Rec
300
Adt Jan-10 Dec-15 Washington
Sen
University (US)
Lumbar Spine Disc
Herniation; Lumbar
Radiculopathy
Rec
140
Endoscopic discectomy versus
microdiscectomy
RCT
ISRCTN11556571
An Evaluation of Interlaminar
Lumbar Instrumented (ILIF™)
NCT01019057
Spondylolisthesis Treated With an
iO-Flex® System Enabled
Decompression
efficacy study
NCT01338766
Microdiscectomy;
Endoscopic
discectomy
Single level disease, Active
L3/4, L4/5, L5/S1
140
Adt Feb-10 Mar-15 The London
Spine Centre;
The Physicians'
Services
Incorporated
Foundation;
Lawson Health
Research
Institute
Adt May-06 Jan-15 Joimax GmbH http://www.controlled(Germany)
Procedure: ILIF
Degenerative Disc
Disease
Active,
NR
100
Adt Nov-09 Dec-14 NuVasive
Sen
Procedure:
Decompression
using the iO-Flex™
system
Radiculopathy;
Spondylolisthesis;
Lumbar Spinal
Stenosis
Invite
150
Adt Apr-11 Nov-14 Baxano, Inc.
Sen
65
Study of NeoFuse in Subjects
Requiring Lumbar Interbody
Fusion
study
NCT00996073
Procedure: Lumbar Degenerative Disc
Active, 24
Interbody Fusion with Disease;
NR
Autograft; Procedure: Degenerative
Lumbar Interbody
Spondylolisthesis;
Fusion with
Spinal Stenosis
NeoFuse; Procedure:
Lumbar Interbody
Fusion with NeoFuse
Greenwich Lumbar Stenosis SLIP Procedure: Lumbar Spinal Stenosis;
Active, 64
Study
Laminectomy with
Spondylolisthesis
NR
Instrumented Pedicle
NCT00109213
Screw Fusion;
Procedure: Lumbar
Laminectomy
PEEK and Allograft Spacers
Procedure:
Degenerative Disc
Rec
240
Evaluation in Spinal Fusion
Posterior/Transforam Disease
Surgeries
inal Lumbar
Prospective, case control study Interbody Fusion
NCT01406405
(P/TLIF), Anterior
Cervical Discectomy
and Fusion (ACDF)
Efficacy and Safety Study of
Procedure: The
Degenerative
Rec
82
Lumbar Interbody Fusion With
Transforaminal
Osteoarthritis;
MatriTMBONE Associated With
Lumbar Interbody
Degenerative
Autologous Bone Marrow
Fusion (TLIF)
Lumbar Vertebra
surgery
NCT01335243
Minimally Invasive Surgery in
Procedure:
Adult Spinal Cord
Not yet 30
Treating Patients With Spinal
therapeutic
Neoplasm;
Rec
Tumors
conventional surgery; Childhood Spinal
RCT, efficacy study
Procedure:
Cord Neoplasm;
NCT01308489
therapeutic
Recurrent Adult
conventional surgery; Spinal Cord
Procedure: quality- Neoplasm;
of-life assessment
Recurrent Childhood
Spinal Cord
Neoplasm; Spinal
Bone Metastases;
Spinal Cord
Metastases
66
Adt Sep-09 Jul-14 Mesoblast, Ltd.
Sen
Adt May-02 Jul-14 Greenwich
Sen
Hospital
Adt
Sen
Jul-11
Jul-14 Justin Parker
Neurological
Institute; Boulder
Neurosurgical
Associates
Adt May-11 May-14 University
Hospital,
Bordeaux;
Biom'up
Adt Dec-11 Mar-14 City of Hope
Sen
Medical Center;
National Cancer
Institute (NCI)
Value of Functional Anesthetic and Procedure:
Discogenic Pain;
Provocative Discography in the
Functional anesthetic Low Back Pain
Surgical Treatment of Discogenic discography;
Pain
Procedure:
Provocative
NCT01077947
Discography
A Randomized, Equivalence Trial Procedure: Caudal Low Back Pain
of Percutaneous Lumbar
Epidural Injection;
Adhesiolysis and Caudal Epidural Procedure:
Steroid Injections
percutaneous
adhesiolysis
NCT01053273
The Effect of Ozone Therapy for Procedure:
Lumbar Herniated
Lumbar Herniated Disc
Discectomy/ micro Disc
discectomy; Drug:
NCT00566007
Ozone therapy;
Drug: Oxygen
therapy
Surgical Treatment for
Procedure: Surgical Scoliosis;
Degenerative Scoliosis
correction of the
Kyphoscoliosis
deformity
NCT01439906
Management of Myelomeningocele Procedure: Prenatal Meningomyelocele;
Study (MOMS)
Myelomeningocele Spinal Dysraphism
Repair Surgery;
NCT00060606
Procedure: Postnatal
Myelomeningocele
Repair Surgery
Cost Effectiveness and Clinical
Procedure: Cell
Low Back Pain
Utility of Cell Saver Use for Two to Saver; Procedure:
Unresponsive to
Three Level Lumbar Fusions
No Cell Saver
Non-surgical Care
RCT, efficacy study
NCT01453309
Effectiveness of Lumbar Fusion
Procedure: NanOss Degenerative Disc
When NanOss Bioactive Is Used Bioactive bone void Disease; Spinal
With Posterolateral Gutter Fusions filler used in
Stenosis;
posterolateral gutter Spondylolisthesis
NCT01452516
fusions
Wdrwn 224
Adt Feb-10 Feb-14 Northwestern
University;
Medtronic Spine
LLC
Invite
120
Adt Feb-10 Jan-14 Pain
Sen
Management
Center of
Paducah
Rec
156
Rec
60
Adt Dec-08 Jan-14 Kovacs
Sen
Foundation;
Fondo de
Investigacion
Sanitaria;
Hospital Negrín;
Hospital Son
Llatzer; Servicio
de Salud de las
Islas Baleares
Adt Jan-10 Dec-13 Istituto
Sen
Ortopedico
Rizzoli
Active,
NR
183
Rec
100
Adt Feb-03 Nov-13 Eunice Kennedy http://ClinicalTrials.gov/show/NCT00060606
Sen
Shriver National
Institute of Child
FHealth and
only
Human
Development
Not yet 240 Adt Oct-11 Oct-13 Norton
Rec
Sen
Leatherman
Spine Center
67
Adt
Sen
Jul-10 Sep-13 Pioneer Surgical http://ClinicalTrials.gov/show/NCT01452516
Technology, Inc.
A Post Market Surveillance
Procedure: Surgery Spinal Deformity
Validation to Evaluate the
Effectiveness of the Following
System: Polaris Deformity Spinal
System
Phase IV: Prospective, caseonly study
NCT01220505
Prospective Study of Cerebral
Procedure: Surgical Cerebral Palsy;
Palsy Scoliosis
fusion
Scoliosis
RCT, efficacy study
NCT00958542
SPONGIT: Comparison of Two
Procedure:
Degenerative
Surgical Approaches in the
Circumferential
Spondylolisthesis
Treatment of Degenerative
arthrodesis;
Spondylolysthesis
Procedure:
RCT, efficacy study
Posterolateral fusion
NCT00869882
with instrumentation
Beta-Tricalcium Phosphate Bone Procedure:
Adult Spinal Cord
Graft in Treating Patients
musculoskeletal
Neoplasm; Spinal
Undergoing Surgery For Metastatic complications
Bone Metastases;
Spine Cancer
management/prevent Spinal Cord
ion; Procedure: bone Compression
efficacy study
graft; Procedure:
NCT01407341
quality-of-life
assessment; Other:
questionnaire
administration
Robotic-Assisted Surgery in
Procedure:
Adult Spinal Cord
Treating Patients With Spine
therapeutic
Neoplasm; Spinal
Tumors
conventional surgery Bone Metastases;
Spinal Cord
efficacy study
Metastases
NCT01345903
Neurologic Complications in Spinal Procedure: Routinely Adult Spinal
Deformity Surgery
performed surgical Deformity
correction of spinal
NCT01305343
deformity
Rec
200 Child Sep-10 Sep-13 Biomet, Inc.
Adt
Sen
Rec
45
Child Mar-09 Jul-13 University of
Adt
British Columbia
Rec
70
Adt Jun-09 Jun-13 University
Sen
Hospital,
Bordeaux
Rec
20
Child Jun-11 Jun-13 USC/Norris
Adt
Comprehensive
Sen
Cancer Center;
National Cancer
Institute (NCI)
Not yet
Rec
10
Adt May-12 Jun-13 City of Hope
Sen
Medical Center;
National Cancer
Institute (NCI)
Not yet 240
Rec
68
Adt
Sen
Jul-11 May-13 AOSpine
International;
Scoliosis
Research
Society (SRS)
Actifuse ABX Versus INFUSE in
Posterolateral Instrumented
Lumbar Fusion
RCT
NCT01018771
Reorganization of Brain Functions
in Patients With Cervical
Myelopathy Using fMRI and MRS
NCT00447343
Procedure: Actifuse Degenerative Disc
ABX; Procedure:
Disease
INFUSE, plus
Mastergraft granules
Actifuse ABX Versus INFUSE in
Posterolateral Instrumented
Lumbar Fusion (PLIF) With
Interbody Fusion
RCT
NCT01013389
Evaluation of Minimally Invasive
Microdiscectomy Versus
Conventional Open
Microdiscectomy For Lumbar
Herniated Disc
RCT
NCT00927056
Preoperative Embolization in
Surgical Treatment of Spinal
Metastases.
RCT, efficacy study
NCT01365715
Study on the Treatment of
Degenerative Lumbar Spine
Stenosis With a Percutaneous
Interspinous Implant
NCT01057641
Procedure: Actifuse Degenerative Disc
ABX; Procedure:
Disease
INFUSE, plus master
granules (MGG)
Procedure:
Spinal Cord
Decompressive
Diseases
cervical spine
surgery; Procedure:
fMRI and MRS scan
Active,
NR
100
Adt
Sen
Jul-09 Dec-12 Apatech, Inc.
Rec
35
Active,
NR
100
Adt Sep-08 Aug-12 Lawson Health
Sen
Research
Institute; The
Physicians'
Services
Incorporated
Foundation;
American
Association of
Neurological
Surgeons
Adt Jun-07 Jul-12 Apatech, Inc.
Sen
Procedure:
Microdiscectomy
Lumbar Herniated
Disc
Invite
50
Adt Jun-09 Jun-12 University of
Sen
Manitoba
Procedure:
Preoperative
embolization;
Procedure: Control
group
Procedure: Spacer
implantation;
Procedure:
physiotherapy
Spinal Metastases
Rec
64
Adt May-11 Jun-12 Rigshospitalet,
Sen
Denmark
Lumbar Spinal
Stenosis
Rec
22
Adt Mar-11 Jun-12 University of
Sen
Cologne
69
Accuracy of Lumbar Pedicle Screw Procedure: Electric Spine Pedicle Screw
Placement Assisted With
pulse train
Placement
Continuous Pulse-train Stimulation stimulation
NCT01342588
Evaluating the Accuracy of
Procedure:
Pedicle Screw of
Navigation Assisted Pedicle Screw navigation assisted Fixation
Placement of Spine Surgery
spine surgery;
Procedure: traditional
NCT01247948
spine surgery
Treatment of Lumbar Spinal
Procedure: Minimal Lumbar Spinal
Stenosis; Comparison of Two
invasive
Stenosis;
Different Surgical Methods; Mini- decompression;
Radiculopathy;
invasive Decompression to X-stop Procedure:
Decompression,
RCT, efficacy study
Interspinous Process Surgical
NCT00546949
Decompression
(IPD)
Gait and Postural Stability
Procedure: posterior Scoliosis
Assessment in Children With
spine fusion
Idiopathic Scoliosis Undergoing
Posterior Spine Instrumentation
NCT01109082
SOLAS® Spinal Surgery Registry Procedure: Surgery Vertebra;
Degeneration; Spinal
NCT01372592
Trauma; Spinal
Deformity
Procedure: PLF with Degenerative Disc
NeoFuse in Subjects Requiring
autograft; Genetic: Disease;
Posterolateral Lumbar Fusion
PLF with NeoFuse; Degenerative
Phase I/II: RCT, safety study
Genetic: PLF with
Spondylolisthesis;
NCT00810212
NeoFuse; Genetic: Spinal Stenosis
PLF with NeoFuse
Real-time Ultrasound-guided
Procedure: Real-time Ultrasound Spinal
Spinal Anesthesia:A Feasibility
ultrasound guided
Anesthesia
Study
spinal anesthesia
NCT01326988
Rec
60
Adt Jan-11 May-12 American British http://ClinicalTrials.gov/show/NCT01342588
Sen
Cowdray
Medical Center
Not yet 656
Rec
Adt Feb-11 Feb-12 Beijing Jishuitan http://ClinicalTrials.gov/show/NCT01247948
Sen
Hospital
Rec
180
Adt Mar-07 Dec-11 Norwegian
Sen
University of
Science and
Technology
Rec
33
Child Dec-07 Dec-11 Shriners
Adt
Hospitals for
Children; Hainer
Foundation;
DePuy Spine
Invite 10000 Child Mar-11 Dec-11 NuVasive
Adt
Sen
Active,
NR
24
Adt Nov-08 Nov-11 Mesoblast, Ltd.
Sen
Comp
100
Adt Apr-11 Oct-11 Sunnybrook
Sen
Health Sciences
Centre
70
A Clinical Study of the GO-LIF®
Approach for Lumbar Spinal
Fixation
NCT00810433
Vertos Mild - Post Market Patient
Outcomes
NCT01076244
Percutaneous Diskectomy
SpineJet x Open Microdiskectomy
in Treatment of Lumbar
Radiculopathy
study
NCT01367860
Evaluation of Radiographic and
Patient Outcomes Following
Lumbar Spine Fusion Using
Demineralized Bone Matrix (DBM)
Mixed With Autograft
NCT00254852
Robotic Assisted Vertebral Body
Augmentation - a Radiation
Reduction Tool
NCT01269359
Fusion Assessment Clinical Trial
NCT00736398
Procedure: GO-LIF - Lower Back Pain
Guided Oblique
Lumbar Interbody
Fusion
Rec
40
Adt Feb-09 Aug-11 Mazor Surgical
Sen
Technologies,
Ltd.
Procedure: Minimally Lumbar Spinal
Invasive Lumbar
Stenosis
Decompression
Active,
NR
50
Adt Feb-10 Aug-11 The Center for http://ClinicalTrials.gov/show/NCT01076244
Sen
Pain Relief, Inc.;
Vertos Medical,
Inc.
Procedure: Open
Radiculopathy;
microdiscectomy;
Herniated Disk
Procedure:
Percutaneous
Diskectomy SpineJet
Rec
60
Adt Jan-11 Aug-11 University of Sao http://ClinicalTrials.gov/show/NCT01367860
Sen
Paulo
Active,
NR
94
Adt Oct-05 Aug-11 Exactech
Sen
Procedure: Posterior Stenosis;
Lateral Fusion (PLF); Spondylolisthesis;
Procedure: Anterior Degenerative Disc
Lumbar Interbody
Disease
Fusion (ALIF);
Procedure:
Transforaminal
lumbar interbody
fusion (TLIF);
Procedure: Posterior
lumbar interbody
fusion (PLIF);
Procedure: Extreme
lateral interbody
fusion (XLIF)
Procedure: robotic Vertebral Body
assisted surgery
Augmentation
Procedure: Spinal
fusion
Degenerative Disc
Disease
Not yet 100
Rec
Rec
50
71
Adt
Sen
N/K
Aug-11 Hadassah
Medical
Organization
Adt Aug-08 Jun-11 Flexuspine, Inc. http://ClinicalTrials.gov/show/NCT00736398
Sen
Cost effectiveness and quality of X-STOP®
Neurogenic
life after treatment of lumbar spinal interspinous
intermittent
stenosis with the X-STOP®
distractor; Lumbar
claudication
Interspinous Process Distraction laminectomy
secondary to lumbar
(IPD) device or laminectomy: a
spinal stenosis
prospective randomised trial
RCT
ISRCTN88702314
Incidence of Proximal Junctional Procedure:
Scoliosis; Kyphosis
Kyphosis (PJK) in Long Posterior Traditional
Spinal Fusion: A Study Comparing technique;
Traditional Open Surgery to
Procedure: Minimally
Minimally Invasive Percutaneous invasive technique
Technique at the Proximal Fusion
Levels
RCT, efficacy study
NCT00890227
Effectiveness of Percutaneous
Procedure:
Chronic Low Back
Lumbar Epidural Adhesiolysis and Percutaneous
Pain
Neurolysis on Low Back Pain
adhesiolysis with
hypertonic saline
NCT00370994
neurolysis; Device:
RK needle and Racz
catheter system;
Drug: local
anesthetic, steroid,
10% sodium chloride
solution
Dynamic Stabilization Versus
Procedure: standard; Degeneration of
Fusion
Procedure: new
Lumbar
Intervertebral Disc
NCT01365754
Pilot study on the effect of
Intradiscal Pulsed
Discogenic low back
Intradiscal Pulsed RadioFrequency RadioFrequency
pain
treatment for the management of treatment
low back pain and ischialgia of
discogenic origin
Observational study
ISRCTN46778702
Comp
110
College London trials.com/ISRCTN88702314
Hospitals NHS
Foundation Trust
(UK)
Not yet
Rec
68
Adt Jun-09 May-11 Johns Hopkins
Sen
University
Active,
NR
320
Adt Jan-06 Apr-11 Pain
Sen
Management
Center of
Paducah
Rec
440
Adt Sep-11 Apr-11 Technische
Sen
Universität
München
Comp
50
Adt Mar-08 Feb-11 Orbis Medical
Sen
Centre SittardGeleen
(Netherlands)
72
Evaluation of the Prosthetic Disc
Replacement
RCT, efficacy study
NCT00640029
Procedure:
Arthrodesis; Device:
Arthroplasty
(PRODISC-C® ,
PRODISC-L®, MobiC®, Mobidisc®,
PrestigeLP®, AMav®, O-Mav®,
DISCOCERV®)
Efficacy and Safety Study of Non- Procedure: non
percutaneous Vertebroplasty With percutaneous
Macroporous Calcium Phosphate vertebroplasty
Cement (MCPC)
NCT00931333
The Effect of Pressure Controlled Procedure: volume
Ventilation on the Pulmonary
control; Procedure:
Mechanics in Prone Position Using pressure control
the Wilson Frame: A Comparison
With Volume Controlled Ventilation
RCT, efficacy study
NCT01272700
The Effect of Epiduroscopy and
Procedure:
Ozone Therapy in Patients With
Epiduroscopy with
Failed Back Surgery Syndrome
oxygen therapy;
Procedure:
study
Epiduroscopy with
NCT01172457
ozone therapy
Procedure: SingleEffectiveness of DIAM™ Spinal
Level Posterior
Stabilization System vs.
Decompression;
Decompression, Formerly vs.
Device: DIAM Spinal
Posterolateral Fusion
Stabilization
study
NCT00627497
Lumbar
Degenerative Disc
Disease; Cervical
Degenerative Disc
Disease; Kyphosis
Term
301
Adt Feb-08 Feb-11 Assistance
Paris
Vertebra Trauma
Comp
4
Adt
Jul-09 Feb-11 University
Hospital,
Bordeaux
Herniation of Lumbar Comp
Vertebral Disc
40
Adt Aug-10 Jan-11 Yonsei
University
Low Back Pain;
Failed Back Surgery
Syndrome
Rec
30
Adt May-09 Dec-10 University of Sao http://ClinicalTrials.gov/show/NCT01172457
Sen
Paulo
Degenerative
Lumbar Spinal
Stenosis
Term
26
Adt Feb-08 Dec-10 Medtronic Spinal http://ClinicalTrials.gov/show/NCT00627497
Sen
and Biologics
73
Intravenous Fentanyl or Local
Anesthetic Infiltration for Pain
Reducing During Spinal Needle
Insertion
NCT01157247
Ultrasound-assisted Spinal
Anaesthesia in Patients With
Difficult Anatomical Landmarks
RCT, efficacy study
NCT00956137
VERTOS-II. Percutaneous
Vertebroplasty Versus
Conservative Therapy
NCT00232466
Procedure:
Anesthesia; Spinal
Comparison of
Puncture
intravenous fentanyl
and local anesthetic
infiltration in pain
reducing during
spinal needle
puncture
Procedure:
Spinal Anesthesia
Ultrasound guidance;
Procedure: Manual
palpation
Comp
88
Adt
Rec
180
Adt May-09 Jun-10 University Health http://ClinicalTrials.gov/show/NCT00956137
Sen
Network,
Toronto
Procedure:
Vertebroplasty
Osteoporosis; Back
Pain
Active,
NR
200
Vertebral
metastases of
Multiple Myeloma
Comp
104
Adt Oct-05 May-10 UMC Utrecht;
Sen
ZonMw: The
Netherlands
Organisation for
Health Research
and
Development
Adt Jun-07 Mar-10 Erasmus
Medical Centre trials.com/ISRCTN48083859
(The
Netherlands)
Patients With
Paraspinal or
Paraspinal
Metastases
Rec
90
Adt Jun-11 Sep-16 University Health http://ClinicalTrials.gov/show/NCT01290562
Sen
Network,
Toronto
Spinal Metastases;
Vertebral
Metastases; Benign
Spinal Tumors;
Chordoma;
Meningioma;
Schwannoma;
Neurofibroma;
Paragangliomas;
Arteriovenous
Malformations
Rec
50
Adt Sep-08 Sep-15 St. John's Mercy http://ClinicalTrials.gov/show/NCT01347307
Sen
Research
Institute, St.
Louis
VErtebroplasty versus
Vertebroplasty;
Radiotherapy As palliative
Radiotherapy
treatment of vertebral metastases
of Multiple Myeloma (M. Kahler)
Other
Stereotactic Body Radiotherapy
(SBRT) for Spinal/Para-Spinal
Metastases (Spine SBRT)
NCT01290562
Radiation:
Stereotactic Body
Radiotherapy
(SBRT); Radiation:
Stereotactic Body
Radiotherapy
(SBRT)
Stereotactic Body Radiotherapy for Radiation:
Spine Tumors
stereotactic body
radiotherapy;
Radiation:
study
stereotactic body
NCT01347307
radiotherapy
74
Apr-09 Jul-10 Croatian Society http://ClinicalTrials.gov/show/NCT01157247
of Regional
Anesthesia and
Analgesia
Image-Guided Radiosurgery or
Stereotactic Body Radiation
Therapy in Treating Patients With
Localized Spine Metastasis
Phase II/III: RCT
NCT00922974
Intervertebral Disc Augmentation
With Minimally Invasive Surgical
Procedure
NCT01442922
Isometric Muscle Training in
Patients With Spinal Bony
Metastases Under Radiation
Therapy
study
NCT01409720
High Dose Intensity Modulated
Proton Radiation Treatment +/Surgical Resection of Sarcomas of
the Spine, Sacrum and Base of
Skull
study
NCT01346124
Epidural Steroid Injection Versus
Epidural Steroid Injection and
Manual Physical Therapy and
Exercise in the Management of
Lumbar Spinal Stenosis
RCT
NCT00786981
Radiation: external
beam radiation
therapy; Radiation:
image-guided
radiation therapy;
Radiation:
radiosurgery;
Radiation:
stereotactic body
radiation therapy
Other: completion of
the (VAS) for level of
back pain; Other:
completion of the
(OLBPQ) for
assessment of
function
Other: exercise
Metastatic Cancer;
Pain
Rec
283
Adt Nov-09 Jul-15 Radiation
Sen
Therapy
Oncology Group;
National Cancer
Institute (NCI)
Degenerative Disc
Disease
Rec
25
Adt Mar-11 Mar-15 University of
Florida
Not yet
Rec
60
Sen
Heidelberg; Dept
of Radiation
Oncology,
University of
Heidelberg,
Germany
Adt Jul-11 Sep-14 Massachusetts http://ClinicalTrials.gov/show/NCT01346124
Sen
General
Hospital; M.D.
Anderson
Cancer Center;
National Cancer
Institute (NCI)
Vertebral Bony
Metastases
Radiation: High Dose Chordoma of Spine; Not yet 120
Intensity Modulated Chordoma of
Rec
Proton Radiation
Sacrum; Chordoma
of Base of Skull;
Chondrosarcoma of
the Spine;
Chondrosarcoma of
the Sacrum
Other: Epidural
Lumbar Spinal
steroid injection plus Stenosis
physical therapy;
Other: Epidural
steroid injection
Rec
80
75
Adt Apr-09 May-14 Franklin Pierce
Sen
University;
University of
Colorado,
Denver
AttraX® Putty in spinal interbody
fusion: Evaluation of radiographic
and clinical outcomes
assignment
ISRCTN38726728
This Study is to Determine if
Degenerative Spinal Pain and
Disorders Cause the Levels of
Substance P to Change in a
Patients Saliva, Blood and/or
Cerebrospinal Fluid.
NCT01458938
Patient Positioning in Lumbar
Fusion Surgery and Its Impact on
Spinal Sagittal Balance and
Surgeon Satisfaction
RCT, efficacy study
NCT01326091
Voice and Swallowing Outcomes
Following Revision Anterior
Cervical Spine Surgery
NCT01017055
Collecting Bone Graft During
Spinal Decompression and
Posterolateral Lumbar Fusion to
Better Define Bone Making Cells
NCT01409954
Low Back Study to Compare
Traditional Physical Therapy With
Combined Therapy Protocol
RCT, efficacy study
NCT01236092
Anterior Approach
Persistent back
Cervical Interbody
and/or leg pain
Fusion; Anterior
unresponsive to
Approach Lumbar
conservative
Interbody Fusion;
treatment
Posterior Approach
Lumbar Interbody
Fusion
Other: treatment plan Spinal Disease,;
Spinal
Radiculopathy,;
Myelopathy;
Neurogenic
Claudication
Active
150
Adt Dec-11 Dec-13 NuVasive, Inc.
Sen
(USA)
Invite
40
Adt
Other: Hyperlordotic Intervertebral Disk
Positioning
Degeneration
Rec
52
Adt Mar-11 Mar-13 Duke University http://ClinicalTrials.gov/show/NCT01326091
Other: Voice and
Swallowing
evaluations
Rec
50
Adt Oct-09 Mar-13 University of
Sen
Alabama at
Birmingham
Genetic: Autologous Pseudarthrosis After
Bone Harvest
Fusion or
Arthrodesis
Invite
60
Adt Oct-11 Jan-13 University of
Sen
Utah
Other: conservative Radiculopathy; Low
therapy - traction,
Back Pain
vibration, exercise
Not yet
Rec
36
Adt
Dysphagia;
Dysphonia
76
Jul-09 Oct-13 Carolina
Neurosurgery &
Spine
Associates
Jan-11 Dec-12 Legend
Healthcare
Spinal Fusion and Rehabilitation
Study
NCT00834015
Other: Outcome of
lumbar spinal fusion
patients and
significance of
postoperative
exercise therapy:
RCT
The Value of Traction in Treatment Other: Physical
of Lumbar Radiculopathy
therapy
NCT00942227
Physical therapy
rehabilitation
Resistance Exercise Effects on
Fear Avoidance and Physical
Function in Obese Older Adults
With Low Back Pain
RCT, efficacy study
NCT01250262
Spondylolisthesis,
Degenerative;
Spondylolisthesis,
Isthmic
Rec
100
Sciatica;
Radiculopathy;
Spinal Diseases;
Musculoskeletal
Diseases;
Neuromuscular
Diseases;
Intervertebral Disk
Displacement
Low Back Pain;
Obesity
Rec
120
Other: normal
Rec
medical care and
follow up; Other:
Isolated Lumbar
Resistance Exercise
Program; Other:
Total Body
Resistance Exercise
Program
Effects of a Walking Program on Other: Walking
Lumbar Spinal
Invite
Functional Status of Post-Surgical program
Stenosis
Lumbar Spinal Stenosis Patients
RCT
NCT00958490
Strategy for Maintaining Partial
Other: TOF count
Brain Surgery With
Rec
Neuromuscular Blocking Adequate guided adjustment; Motor Evoked
for Motor Evoked Potential During Other: T1/ T0 guided Potential Monitoring;
Neurosurgery
adjustment; Other: Spine Surgery With
RCT, safety study
T2/ T0 guided
Motor Evoked
NCT01388868
adjustment
Potential Monitoring
Arterial Pulse Waveform Contour Other: goal directed Surgical Procedures, Rec
Analysis for Intraoperative Goal
therapy
Operative
Directed Therapy in Major Spine
Surgery
RCT, efficacy study
NCT01124474
Adt May-10 Dec-12 Jyväskylä
Sen
Central Hospital;
Tampere
University
Hospital;
University of
Tampere
Adt Jul-09 Dec-12 Intermountain
Health Care,
Inc.; University
of Utah; Wilford
Hall Medical
Center; Empi, A
DJO Company
60
Adt Nov-10 Nov-12 University of
Sen
Florida
50
Sen
Manitoba
90
Adt Jun-11 May-12 Samsung
Sen
Medical Center
60
Adt Dec-10 Apr-12 Loma Linda
Sen
University
77
Rehabilitation Following Lumbar Other: Rehabilitation
Disc Surgery
following lumbar disc
RCT, efficacy study
surgery (discectomy)
NCT00894972
Study of 3 Doses of NeoFuse
Genetic: NeoFuse;
Combined With MasterGraft
Procedure:
Granules in Subjects Requiring
posterolateral spinal
Posterolateral Lumbar Fusion
fusion with
(PLF)
instrumentation
Phase I/II: RCT, safety study;
NCT00549913
Do Lower Spine Injections Improve Other: Observation
Outcomes for Lower Back Pain
of biomechanical
Patients
effects post injection
NCT01381224
Intraocular Pressure During Prone Other: table tilt
Spinal Surgery
Phase II: Prospective study
NCT00176722
Lumbar Disc
Herniation;
Radiculopathy
Rec
70
Adt
Active,
NR
40
Adt Oct-07 Mar-12 Mesoblast, Ltd.
Sen
Low Back Pain
Rec
30
Adt Jan-11 Jan-12 University of
Sen
Florida
Spine Surgery;
Vision Impairment
Term
7
Adt
Post Market Study of the
Other: Physical
Electrophysiological Course of Low Therapy
Back Pain Using CERSR
Technology
NCT01403870
Evaluation of the Brain Activity
Other: fMRI and
During Spinal Cord Stimulation in MRS
Failed Back Surgery Syndrome
Using Functional MRI and MRS
NCT01181817
Low Back Pain
Term
6
Failed Back Surgery
Syndrome
Rec
40
Degenerative Disc
Disease;
Spondylolisthesis;
Spinal Stenosis
78
Apr-09 Apr-12 University of
Utah
Jun-06 Jan-12 University of
Medicine and
Dentistry New
Jersey;
Foundation for
Anesthesia
Education and
Research; New
Jersey Eye
Institute
Adt Apr-11 Nov-11 Verium
Sen
Diagnostics, Inc.
Adt Sep-08 Sep-11 Universitair
Sen
Ziekenhuis
Brussel; Maarten
Moens
Establishment of Optimal
Transfusion Threshold During
Spine Surgery
RCT, efficacy study
NCT00967109
Other: Allowed drop Anemia; Spine
Comp 60
in hemoglobin to
Surgery
level between 4,5-5,6
mmol/L; Other:
Allowed drop in
hemoglobin to level
between 5,6-6,5
mmol/L
A Study on the Use of Educational Other: Educational Decompression,
Not yet 70
Programs Prior to Lumbar Spinal program
Surgical
Rec
Surgery
RCT
NCT00719485
Stereotactic Body Radiation
Radiation:
Metastatic Cancer;
Rec
42
Therapy and Vertebroplasty in
stereotactic body
Pain; Unspecified
Treating Patients With Localized radiation therapy
Adult Solid Tumor,
Spinal Metastasis
Protocol Specific
Phase II
NCT00855803
Efficacy of Surgical Preparations in Other: DuraPrep;
Infection
Comp 100
Lumbar Spine Surgery
Other: ChloraPrep
RCT, efficacy study
NCT01105195
Study Evaluating the Safety of
Other: There is no
Ankylosing
Term 880
Etanercept in Rheumatoid Arthritis, Intervention. The
Spondylitis; Arthritis,
Ankylosing Spondylitis and
study is
Psoriatic; Arthritis,
Psoriatic Arthritis
observational.
Rheumatoid;
Spondylitis,
NCT00273858
Ankylosing
Neurological Surgery & Affiliated
Services De-Identified Clinical
Outcomes Database
NCT00593411
Cognitive Dysfunction in
Hypertensive Patients Having
Spine Surgery
NCT01140854
Central Nervous
System Disorder;
Spinal Diseases;
Peripheral
Neuropathy
Hypertension
Rec
Adt Sep-09 Feb-11 Rigshospitalet,
Sen
Denmark;
TrygFonden,
Denmark
Adt Apr-09 Feb-11 Sunnybrook
Sen
Health Sciences
Centre
Adt Feb-09 Feb-11 Simmons
Sen
Cancer Center
Adt Jan-10 Nov-10 Northwestern
Sen
University; 3M
Adt Mar-06 Jul-10 Wyeth is now a
Sen
wholly owned
subsidiary of
Pfizer
10000 Child Jun-05 Jun-15 University of
Adt
Sen
Rec
150
79
California, Irvine
Adt Jan-09 Dec-14 Columbia
Sen
University;
Mount Sinai
School of
Medicine; Weill
Medical College
of Cornell
University
XLIF® vs. MAS®TLIF for the
Treatment of Symptomatic Lumbar
Degenerative Spondylolisthesis
With or Without Central Stenosis.
NCT01024699
CopiOs Posterolateral Fusion
Procedure
NCT01123850
Direct Stimulation Of Spinal Nerve
Roots To Determine Sensory And
Motor Innervation Patterns
NCT00696501
Transfusion Requirements During
Spinal Surgery for Severe
Scoliosis
NCT01490164
Effect of HIV Infection and Highly
Active Antiretroviral Treatment
(HAART) on Bone Homeostasis
NCT01020045
Spondylolisthesis
Rec
110
Adt Nov-09 Dec-14 NuVasive
Sen
Spondylolisthesis;
Stenosis
Rec
85
Adt Jun-10 Jun-14 Zimmer, Inc.
Sen
Spine Surgery;
Neuromuscular
Mapping;
Neurodiagnostics
Rec
1000 Adt May-06 May-14 Lahey Clinic
Sen
Scoliosis
Rec
50
HIV Infection;
Osteopenia;
Osteoporosis
Rec
120
Trinity Evolution in Posterior or
Transforaminal Lumbar Interbody
Fusion (PLIF/TLIF)
NCT00965380
Lumbar Spinal Fusion System
Prospective study
NCT00758719
Maverick Total Disc Replacement
in a 'Real World' Patient
Population
NCT01338493
Degenerative Disc
Disease
Active,
NR
200
Degenerative Disc
Disease
Active,
NR
53
Degenerative Disc
Disease
Active,
NR
150 Child Feb-09 Feb-13 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01338493
Adt
& Biologics ECA
Sen
80
Child Aug-09 Mar-14 University of
Adt
Medicine and
Dentistry New
Jersey
Adt
Oct-10 Jan-14 Emory
University;
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Adt Sep-09 Nov-13 Orthofix Inc.
Sen
Adt Sep-08 Jul-13 Biomet, Inc.
Sen
Analysis of Tokuhashi Score
NCT01210508
Cancer; Metastases;
Spinal metastases
Invite
Prospective Study of
Scheuermann's Kyphosis
NCT00738309
Multi-Center Prospective
Evaluation of Operative Versus
Nonoperative Treatment for Adult
Spinal Deformity
NCT00738439
Center Blade Study
NCT01499680
A Prospective, Multicenter
Observational Study on MAST™
(Minimal Access Spinal
Technologies) Fusion Procedures
for the Treatment of the
Degenerative Lumbar Spine
NCT01143324
Prospective Study of Minimally
Invasive Spine Surgery
Prospective study
NCT01045473
Scheuermann's
Kyphosis
Invite
Spinal Deformity
Invite
Assessment of Central Pain in
Patients Who Undergo Spinal
Surgery and Influence in Surgery
Outcome
NCT01299818
Degeneration of
Invite
Lumbar
Intervertebral Disc
Degenerative
Active,
Lumbar Spine
NR
Causing Back and/or
Leg Pain;
Degenerative
Lumbar Spine
Pathology
167 Child Mar-09 Dec-12 State University http://ClinicalTrials.gov/show/NCT01210508
Adt
of New York Sen
Upstate Medical
University;
Cleveland Clinic
Florida
240 Child May-06 Dec-12 Children's
Adt
Specialists
Foundation;
DePuy Spine
936 Adt Oct-08 Dec-12 Children's
Sen
Specialists
Foundation;
DePuy Spine
300
Adt Oct-11 Oct-12 NuVasive
Sen
250
Adt Jun-10 Oct-12 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01143324
Sen
& Biologics ECA
Degenerative Disk
Not yet 450
Disease;
Rec
Spondylolisthesis;
Spinal Stenosis;
Degenerative
Scoliosis
Spinal Surgery; Pain Not yet 50
Rec
81
Adt Jan-10 Jun-12 Society for
Sen
Minimally
Invasive Spine
Surgery
Adt Mar-11 Apr-12 Tel-Aviv
Sen
Sourasky
Medical Center
Stabilimax Investigational Device
Exemption (IDE) Clinical
Investigation Patient Followup
Study
NCT01485289
NeuroVision® Dynamic Screw
Test Study
Prospective study
NCT01232517
Antiplatelet Therapy Continuation
in Spine Surgery - Its Effect on
Postoperative Morbidity and
Mortality
NCT01006083
Satellite™ PEEK Nucleus
Replacement Retrospective
Analysis
NCT01110967
Physical Capability Outcomes
After Single-Level PD-L vs SingleLevel ALIF: a Multi-Center Clinical
Trial
NCT01055574
Progression of Spinal Fusion in
NCT00085995
Use of ROTEM for Multi-level
Spine Surgery
NCT00839995
Pilot Study on the Effect of
Dexmedetomidine on Inflammatory
Responses in Patients Undergoing
Lumbar Spinal Fusion
NCT01377623
Spinal Stenosis
Rec
25
Adt Aug-11 Mar-12 Rachiotek LLC
Sen
Comp
60
Adt Mar-09 Feb-12 NuVasive
Sen
Hemorrhage;
Not yet 200
Cerebrovascular
Rec
Accident; Myocardial
Infarction;
Pulmonary
Embolism; Deep
Vein Thrombosis
Degenerative Disc
Active, 95
Disease, Lumbar;
NR
Disc Herniation,
Lumbar
Adt Jan-10 Feb-12 Tel-Aviv
Sen
Sourasky
Medical Center
Physical Capability
Outcomes
Term
45
Adt
Spondylitis,
Ankylosing
Rec
65
Adt
Sen
Coagulation
Comp
41
Adt
Sen
Rec
56
Adt
Sen
Degenerative Spinal
Conditions
Spinal Stenosis;
Inflammation
82
Adt Apr-10 Feb-12 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01110967
Sen
& Biologics ECA
Oct-09 Jan-12 Gundersen
Lutheran
Medical
Foundation;
Synthes USA
HQ, Inc.
Jun-04 Jan-12 National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Feb-09 Dec-11 Weill Medical
College of
Cornell
University
Sep-10 Dec-11 New York
University
School of
Medicine;
Hospira, Inc.
Pharmacokinetics of Aminocaproic
Acid in Scoliosis Surgery
NCT01408823
Scoliosis
Comp
20
Radiofrequency Nerve Ablation
Versus Sham to Treat Chronic Low
Back Pain Caused by Sacroiliac
Joint Dysfunction
Prospective, case-crossover
study
NCT01104051
Prevalence of Inadvertent
Hyperventilation During
Intraoperative Anesthetic Care
Retrospective, case-only study
NCT01235650
Study and Surgical Treatment of
Syringomyelia
NCT00011245
Sacroiliac Joint
Dysfunction
Comp
39
Spinal Fusion
Comp
160 Child Sep-10 Jul-11 Nationwide
Adt
Children's
Sen
Hospital
Syringomyelia
Comp
50
Evaluation of Radiculitis Following
Use of Bone Morphogenetic
Protein-2 for Interbody Arthrodesis
in Spinal Surgery
NCT00984672
A Prospective Natural History
Study of Patients With
Syringomyelia
Prospective study
NCT01150708
Establishing the Physiology of
Syringomyelia
NCT00001327
Lumbar
Degenerative
Disease
Rec
240
Syringomyelia;
Arnold Chiari
Deformity
Rec
120
Adt Jun-10 Apr-11 National Institute http://ClinicalTrials.gov/show/NCT01150708
Sen
of Neurological
Disorders and
Stroke (NINDS)
Comp
120
Adt
Sen
Comp
38
Posterior Lateral Fusion (PLF)
With Dynesys
NCT00791180
Arnold Chiari
Deformity;
Hydrocephalus;
Syringomyelia
Spondylolisthesis
83
Child Jul-11 Oct-11 Children's
Adt
Hospital of
Philadelphia;
Children's
Anesthesiology
Associates, Ltd.
Adt Apr-10 Sep-11 Coastal
Sen
Orthopedics &
Sports Medicine
Adt Feb-01 May-11 National Institute http://ClinicalTrials.gov/show/NCT00011245
Sen
of Neurological
Disorders and
Stroke (NINDS)
Adt Mar-09 Apr-11 Mayo Clinic
Sen
Jul-92 Mar-11 National Institute http://ClinicalTrials.gov/show/NCT00001327
of Neurological
Disorders and
Stroke (NINDS)
Adt Mar-06 Mar-11 Zimmer, Inc.
Sen
Drug Use Survey (DUS) of Triple
Therapy (Methycobal (MBL)+
Myonal (MYO)+ Non-steroidal Antiinflammatory Drags (NSAID)) on
the Symptom Relief of Lumbar
DDD in China
NCT01299077
Prospective Clinical Evaluation of
the New Aegis Plate for Anterior
Interbody Fusions
NCT00555659
Genetic Determinants of
Ankylosing Spondylitis Severity
NCT00056849
Lumbar Disc
Degenerative
Disease
Comp
478
Adt Jun-10 Nov-10 Eisai China Inc. http://ClinicalTrials.gov/show/NCT01299077
Sen
Degeneration;
Spondylosis;
Spondylolithesis;
Stenosis
Active,
NR
104
Adt Sep-07 Sep-10 Columbia
Sen
Orthopaedic
Group, LLP;
DePuy Spine
Ankylosing
Spondylitis
Minimal Access Surgical
Technique (MAST) in Obese
Patients in Degenerative Lumbar
Disease
NCT01195584
Intraocular Pressure During Spine
Surgery
NCT00593359
Degenerative
Lumbar Disease
2000 Adt Mar-03 Jul-10 National Institute http://ClinicalTrials.gov/show/NCT00056849
Sen
of Arthritis and
Musculoskeletal
and Skin
Diseases
Comp 72
Adt May-10 Jul-10 General Hospital http://ClinicalTrials.gov/show/NCT01195584
Sen
Amstetten
Intraocular Pressure
Comp
Rec
60
84
Adt Dec-07 Feb-10 Outcomes
Sen
Research
Consortium
A4. THORAX
Title
CT ID
Device
Sternal Closure With
STERNUMFIX in Patients With
High Risk
study
NCT01408745
Infection Rate of Vertical
Expandable Prosthetic Titanium
Rib Implants (VEPTR)
NCT01085669
Interventions
Flail Chest - Rib Fixation Study
study
NCT01147471
Evaluation of Surgical Treatment
on Pain and Disability for Chronic,
Non-healing Rib Fracture
NCT00774618
Device: operative rib Flail Chest
fixation
Evaluation of Primary Plating in
Sternotomy Patients for
Osteosynthesis and Pain
study
NCT00819286
Conditions
Recruit
n
Age Start
(Grp) Date
End Sponsors
Date
Device: Sternumfix; Sternum Wound
Procedure: steel wire Infection; Nonunion
of Fracture of
Sternum
Rec
415 Child Jun-08 Nov-12 Aesculap AG
Adt
Sen
Device:
Microbiological
analysis of retained
VEPTR Implants
Rec
50
Infection
Device: RibLoc ® Rib Rib Fracture
Fracture Plating
System,
BioBridge™Bioresor
bable Bone Fracture
Plate System Other:
Operative
management without
a device.
Device: SternaLock Sternal Wound
Rigid Fixation
Infection; Sternal
System; Device:
Non-union; Pain;
Wire (control)
Mediastinitis
Rec
Active,
NR
Active,
NR
URL
Child Sep-09 May-12 Centre
Adt
Hospitalier
Universitaire
Vaudois;
University
Children's
Hospital Basel
100 Adt Sep-10 Mar-12 Virginia
Sen
Commonwealth
University;
Synthes Inc.
50
Adt Oct-08 Dec-11 Oregon Health http://ClinicalTrials.gov/show/NCT00774618
Sen
and Science
University;
ACUTE
Innovations, LLC
141
85
Adt Dec-08 Dec-11 Biomet, Inc.
Sen
MatrixRIB Implants for Surgical
Stabilization of Flail Chest Injuries:
A Registry
study
NCT00810251
Pain Relief for Ventilated Patients
With Multiple Rib Fractures Using
the ON-Q Pain Relief System
NCT00880529
Improvement of Hemostasis
Techniques After Median
Sternotomy
study
NCT01134471
Comp
20
Adt Dec-08 May-11 Legacy
Sen
Biomechanics
Laboratory;
Synthes Inc.
Term
48
Adt Feb-09 May-11 Cooper
Sen
University
Hospital
Invite
75
Adt Apr-09 May-11 Aarhus
Sen
University
Hospital;
MCeremed, Inc.
only
Drug: Epidural
Postoperative Pain
Analgesia; Drug:
Patient-Controlled IV
Analgesia
Comp
110 Child Oct-06 Oct-10 Children's Mercy http://ClinicalTrials.gov/show/NCT00413582
Adt
Hospital Kansas
City
Procedure
Delayed Primary Versus Late
Secondary Wound Closure in
Sternum Infections
NCT01473979
Procedure: Surgical Mediastinitis
closure of the
poststernotomy
wound infection
Not yet 100
Rec
Treatment of Acute, Unstable
Chest Wall Injuries
RCT
NCT01367951
Procedure: Surgical
fixation; Procedure:
conservative
treatment
Pain Management for Pectus
Excavatum Repair
RCT, efficacy study
NCT00413582
Flail Chest: A Randomized
Controlled Study
RCT, efficacy study
NCT01308697
Device: MatrixRIB
(FDA Approval #
K081623)
Flail Chest
Device: ON-Q
Rib Fractures
bupivicaine
administration; Drug:
IV opioid
administration
Device: Ostene;
Sternal Dehiscence;
Device: Bonewax
Sternal Infection;
Sternal Pain
Blunt Injury of
Thorax; Flail Chest;
Chest Wall Injury
Trauma; Rib
Fracture
Procedure: Operative Flail Chest
fixation of flail chest;
Other: Non Operative
management
Rec
80
Rec
20
86
Adt Jan-12 Jul-14 University of
Sen
Lausanne
Hospitals;
University
Hospital
Olomouc
Child Jul-11 Dec-13 St. Michael's
Adt
Hospital,
Sen
Toronto
Adt Apr-11 Jul-12 University of
Sen
British Columbia
Trial of Operative Fixation of
Fractured Ribs in Patients With
Flail Chest
study
NCT00298259
Procedure: operative Flail Chest;
fixation of fractured Ventilation
ribs
Other
Prediction and Characterization of Other: Conditioned
Acute and Chronic Postoperative pain modulation
Pain
NCT01308385
VEPTR Implantation to Treat
Children With Early Onset
Scoliosis Without Rib
Abnormalities
NCT00689533
Pain; Pain,
Postoperative;
Funnel Chest;
minimally invasive
repair of pectus
excavatum
Congenital
Progressive
Scoliosis; Infantile
Rec
60
Adt Jan-07 Feb-12 The Alfred
Sen
Not yet 100 Child Apr-11 Oct-12 University of
Rec
Adt
Aarhus
Sen
Rec
250 Child Jan-08 Jan-16 Shriners
Hospitals for
Children; Chest
Wall and Spine
Deformity
Research
Foundation
87
A5. SHOULDER (including clavicle)
A5A: PAEDIATRICS
Title
Interventions
CT ID
Elastic Stable Intramedullary
Nailing of Dislocated Clavicle
Fractures in Children
NCT01325129
Youth Throwers Respond to
Stretching
NCT01065181
Conditions
Recruit
n
Age Start
(Grp) Date
End Sponsors
Date
URL
Dislocated Clavicular Invite
20 Child Apr-11 Dec-11 University of
Fracture Treated
Luebeck
With Elastic Stable
Intramedullary
Nailing
Shoulder Posterior
Active, 1261 Child Jan-08 Dec-10 Metzger,
Capsular
NR
Charles, M.D.
Contracture
Monly
Conditions
URL
Title
CT ID
Device
Outcomes Study of the TM
Humeral Stem Used in Primary,
Total or Hemi Shoulder
Arthroplasty
NCT01480453
Interventions
Device: Trabecular Osteoarthritis;
Metal Humeral Stem Rheumatoid Arthritis;
Post-traumatic
Arthritis; Ununited
Humeral Head
Fracture; Irreducible
3- and 4-part
Proximal Humeral
Fractures; Avascular
Necrosis
Recruit
n
Rec
200
88
Age Start
(Grp) Date
End Sponsors
Date
Adt Jan-11 Dec-24 Zimmer, Inc.
Sen
Outcomes Study of the TM
Device: Trabecular
Reverse Shoulder System Used in Metal Reverse
Primary or Revision Reverse Total Shoulder System
Shoulder Arthroplasty
NCT01480440
Osteoarthritis;
Rheumatoid Arthritis;
Post-traumatic
Arthritis; Ununited
Humeral Head
Fracture; Irreducible
3-and 4-part
Proximal Humeral
Fractures; Avascular
Necrosis; Gross
Rotator Cuff
Deficiency; Failed
Total Shoulder
Arthroplasty (Both
Glenoid and
Humeral
Components
Require Revision)
Humeral Fractures,
Proximal
Treatment of Proximal Humeral
Fractures
study
NCT01246167
Device: Philos;
Device: Epoca;
Other: Control group
Non-Operative Versus Operative
Treatment for High-Energy
Midshaft Clavicle Fractures
RCT
NCT00590850
Device: ORIF with
High Energy
Plate and Screws;
Midshaft Clavicle
Device: Pin Fixation Fractures
Rec
200
Adt Jan-11 Dec-24 Zimmer, Inc.
Sen
Rec
290
Invite
480
Adt Jan-11 Sep-16 Tampere
Sen
University
Hospital; Oulu
University
Hospital; Kuopio
University
Hospital;
University of
Tampere;
Helsinki
University
Adt Oct-03 Dec-13 Greenville
Sen
Hospital System
University
Medical Center;
Orthopaedic
Trauma
Association;
University of
Tennessee;
Vanderbilt
University;
Indiana
University
89
Effectiveness of Intensive
Rehabilitation on Shoulder
Function After Proximal Humerus
Fracture
RCT, efficacy study
NCT01113411
Device: PHILOS™
locked plate system
by Synthes
Canada®; Other:
Early and intensive
exercise program;
Other: Standard
rehabilitation
program
Intramedullary Fixation of Humerus Device: Quantum
Fractures Without Intramedullary
Reaming
NCT01087463
Intramedullary Fixation of Humerus Device: Quantum
Fractures
NCT01017289
Does Teriparatide (rhPTH 1-34)
Drug: Teriparatide
Promote Fracture Healing in
Proximal Humeral Fractures?
NCT01105832
Effect of PTH(1-34) Treatment on Drug: rhPTH(1-34)
Fracture Healing in Vivo
NCT00741182
Fracture of Proximal
Humerus
Rec
80
Adt Dec-09 Oct-13 Hopital de
Sen
l'Enfant-Jesus
Humeral Fractures;
Pathological
Fractures
Not yet
Rec
20
Adt Apr-10 Apr-12 N.M.B. Medical http://ClinicalTrials.gov/show/NCT01087463
Sen
Applications Ltd
Humeral Fractures;
Pathological
Fractures
Not yet
Rec
20
Adt Dec-09 Dec-11 N.M.B. Medical http://ClinicalTrials.gov/show/NCT01017289
Sen
Applications Ltd
Humeral Fracture
Rec
40
Shoulder Fractures;
Trochanteric
Fractures
Rec
A Study of rhBMP-2/CPM in
Drug: rhBMP-2/CPM Fractures, Humerus
(proximal,
Closed Fractures of the Humerus
diaphyseal)
study
NCT00384852
Comp
Adt Apr-10 Sep-11 University
Sen
Hospital,
Linkoeping
Fonly
96
Adt Oct-08 Sep-10 Glostrup
Sen
University
Hospital,
FCopenhagen;
only
The Danish
Medical
Research
Council
139 Adt Jan-07 Feb-10 Wyeth is now a
Sen
wholly owned
subsidiary of
Pfizer
90
Procedure
The Effect of the Timing of
Postoperative Mobilisation After
Locking Plate Osteosynthesis of
Fractures of the Surgical Neck of
the Humerus
NCT01524965
Treatment of Comminuted
Fractures of the Proximal
Humerus. A Randomised,
Controlled Study
study
NCT00999193
Conservative Treatment Versus
the Surgical Treatment of
Diaphyseal Fractures of Humerus
Non-randomized, efficacy study
NCT01116349
Treatment of Displaced, Midshaft
Clavicle Fractures. Sling or Plate?
RCT
NCT01483482
Procedure:
Humeral Fracture
Immediate
mobilisation after
locking-plate
osteosynthesis;
Procedure: Standard
mobilisation after
locking plate
osteosynthesis;
Device:
Osteosynthesis with
a locking plate
(Philos)
Procedure: locking Humeral Fracture
plate, ORIF;
Procedure:
Hemiarthroplasty;
Other: Conservative
treatment
Rec
100
Adt May-11 Dec-15 Helsinki
Sen
University;
National Institute
for Health and
Welfare, Finland
Rec
150
Adt Nov-10 Nov-14 Helsinki
Sen
University;
Helsinki
University
Central Hospital;
National Institute
for Health and
Welfare, Finland
Adt Jan-11 Jul-14 Hopital de
Sen
l'Enfant-Jesus
Procedure: Plate and Humeral Diaphysis
Rec
screws or nailing;
Fracture
Device: Hanging
Support System
(HSS) brace
Procedure:
Acute, Displaced
Rec
Conservative
Midshaft Clavicle
Treatment;
Fractures
Procedure: Surgical
treatment
Multi-centre randomised trial
Surgery (fixation or Displaced fracture of Active
evaluating surgery for displaced
joint replacement); the proximal
fractures of the proximal humerus Non-surgical
humerus
RCT
management (sling
ISRCTN50850043
immobilisation)
70
120
Adt
Apr-11 Apr-14 Hvidovre
University
Hospital
250 Child Oct-08 Feb-14 University of
Adt
Teesside (UK)
Sen
91
Fixation of Midshaft Fractures of
the Clavicle With Plate and
Intramedullary Flexible Nail
study
NCT01410032
Plating Clavicle Fractures
RCT, efficacy study
NCT00871468
Management of Displaced
Supracondylar Fractures of the
Humerus Using Lateral vs.
Crossed K-wires
NCT00358787
Procedure: Fracture Fracture of Shaft of
fixation with Plate.; Clavicle
Procedure: Fracture
fixation with
intramedullar nailing
Rec
40
Procedure: superior Clavicle Fracture,
plate; Procedure:
Non Union/Malunion
anterior-inferior plate
Rec
90
Rec
42
Rec
89
Child Mar-09 Mar-13 St. Michael's
Adt
Hospital,
Toronto
Rec
30
Adt Dec-09 Jan-13 University of
Sen
Aarhus
Rec
140
Adt
Crossed K-wiring of Humeral Fractures
supracondylar
fracture of the
humerus; Lateral Kwiring of
supracondylar
fracture of the
humerus
Conservative Treatment Versus
Procedure: NonClavicle Fracture;
Operative Plate Fixation for Acute, operative Treatment; Fractures
Displaced Fractures of the Distal Procedure: Operative
Clavicle
Treatment
RCT
NCT00872105
Evaluation of Treatment of
Procedure: Winsta Fracture
Fractures of the Humerus With a PH osteosynthesis
Plate.
device
NCT00408291
Conservative Treatment
Operation using a
Displaced Midshaft
Compared to Osteosynthesis in
precontoured
Fracture of the
Patients With a Fractured Collar
titanium plate and
Collar Bone
Bone
screws; Displaced
RCT, efficacy study
midshaft fracture of
NCT01078480
the collar bone
treated with an arm
sling
92
Child Jul-10
Adt
Jul-13 University of Sao http://ClinicalTrials.gov/show/NCT01410032
Paulo
Adt
Oct-08 Jun-13 United States
Army Institute of
Surgical
Research;
William
Beaumont Army
Medical Center
Child Jul-08 Apr-13 University of
British Columbia
Apr-10 Dec-12 Northern
Orthopaedic
Division,
Denmark
Simple Decompression Versus
Anterior Transposition of the Ulnar
Nerve
RCT
NCT01051869
Treatment of midshaft clavicle
fractures: plate fixation versus
figure-of-eight bandage.
RCT
ISRCTN66495030
Lateral Mini Approach vs Anterior
Approach for Plating of Proximal
Humerus Fracture
NCT00612391
Procedure: Simple
decompression;
Procedure: anterior
subcutaneous
transposition
Plate fixation;
Bandage (figure of
eight)
Humeral Fractures;
Ulnar Nerve
Compression
Clavicle fractures
Procedure: Lateral Proximal Humerus
minimally invasive
Fracture
approach (plate
fixation); Procedure:
Deltopectoral
approach (plate
fixation)
Plate Osteosynthesis Versus ESIN Procedure: plate
Clavicular Fractures
of Displaced Midclavicular
osteosynthesis;
Fractures
Procedure: ESIN
study
NCT01015924
The Treatment of Clavicular
Procedure:
Displaced, Midshaft
Fractures
osteosynthesis;
Clavicular Fractures
RCT, efficacy study
Other: sling
NCT00642265
Comparison of Nailing, Plate
Fixation and Non-operative
Treatment of Midshaft Clavicle
Fractures
RCT, efficacy study
NCT01307670
Procedure: Operative Fracture of Clavicle
treatment with
intramedullary
nailing; Procedure:
Operative treatment
with plate fixation.
Other
Percutaneous Versus Open Plate Other: xrays
Fixation of Diaphyseal Clavicle
Fractures
NCT01405703
Clavicle Fracture
Rec
54
Child Sep-10 May-12 St. Michael's
Adt
Hospital,
Toronto
Comp
120
Rec
90
Rec
90
Rec
100
Adt
Invite
30
Adt
Sen
Adt
Jan-08 Jan-12 Universidade
http://www.controlledFederal de Sao trials.com/ISRCTN66495030
Paulo
(UNIFESP)
(Brazil)
Adt Nov-07 Jan-12 University of
Sen
Montreal
Child Jul-09 Dec-11 University
Adt
Hospital,
Akershus
Apr-08 Aug-11 University
Hospital, Ghent;
Bart Berghs, MD
- AZ Sint-Jan
Brugge, Belgium
Wdrwn 400 Child Apr-08 Mar-10 University of
Adt
MissouriSen
Columbia
93
Jul-11
Utah
Study Comparing Intramedullary
Nailing, Plate Fixation, and Nonoperative Treatment of Clavicle
Fractures
RCT, efficacy study
NCT01311219
Other: Non-operative Fracture of Clavicle
Treatment;
Procedure: Operative
Treatment-Plate
Fixation; Procedure:
Operative TreatmentIntramedullary
Pinning
A Clinical Investigation of the
Copeland™ Humeral Resurfacing
Head
NCT00698750
Clinical Outcomes Following
Glenoid Neck Fracture as
Correlated With Quantitative
Assessment of Osseous Injury
NCT00644813
Validation of a Kinematic
Functional Shoulder Score
Including Only Essential
Movements
NCT01431417
Comparison of Early and Late
Therapy for Adults With NonOperatively Treated Proximal
Humerus Fractures
NCT00438633
Operative Versus Non-Operative
Treatment of Clavicle Fracture in
PolyTrauma
study
NCT01133769
Operative Versus Nonoperative
Treatment for Scapula Fractures
NCT00849771
Wdrwn 480 Child May-09 May-11 University of
Adt
MissouriSen
Columbia
Osteoarthritis;
Term
Avascular Necrosis;
Humeral Fractures
160
Adt Apr-04 Apr-15 Biomet
Sen
Orthopedics,
LLC
Scapula
Rec
50
Adt Mar-08 Dec-14 Boston Medical http://ClinicalTrials.gov/show/NCT00644813
Sen
Center
Rotator Cuff,
Syndrome; Frozen
Shoulder; Humerus,
Fracture; Other
Instability of Joint,
Shoulder Region
Proximal Humeral
Fractures
Rec
100
Adt
Sen
Rec
60
Fracture of Clavicle;
Chest Injury
Rec
88
Sen
Kentucky;
Synthes Inc.
Fracture of Scapula;
Fracture of Clavicle
Rec
80
Adt Mar-08 Jan-13 Vanderbilt
Sen
University
94
Jul-11 Feb-14 Haute Ecole
Cantonale
Vaudoise de
Santé; Swiss
National Science
Foundation
Adt Feb-05 Dec-13 Massachusetts http://ClinicalTrials.gov/show/NCT00438633
Sen
General Hospital
Clinical Outcome Comparison
Between Medial and Lateral Offset
Reverse Shoulder Arthroplasty
NCT01086202
An Algorithm for Intra-operative
Goal-directed Haemodynamic
Management in Non-cardiac
Surgery
NCT01384097
Rotator Cuff Injury in Antegrade
Locked Nailing for Humeral
Fractures
NCT00772850
Influence of Local Bone Status on
Complications After Surgical
Treatment of Proximal Humerus
Fractures
NCT01143675
Rotator Cuff Tear;
Proximal Humerus
Fractures;
Malunions; Chronic
Proximal Humerus
Dislocations
Fracture of Surgical
Neck of Humerus;
Colonic Tumor;
Stage IIIB Ovarian
Carcinoma;
Neoplasm of Head
of Pancreas
Humeral Fractures
Proximal Humeral
Fractures; Poor
Bone Quality;
Treatment
Complications
Rec
40
Adt May-10 Apr-12 Loma Linda
Sen
University
Comp
774
Adt Sep-07 Jun-11 Charite
Sen
University,
Berlin, Germany
Comp
50
Child Oct-08 Jun-10 National Taiwan http://ClinicalTrials.gov/show/NCT00772850
Adt
University
Sen
Hospital
Comp
148
Adt Mar-07 Apr-10 AO Clinical
Sen
Investigation and
Documentation
Recruit
n
Comp
100
A5C: ROTATOR CUFF PATHOLOGIES
Title
Interventions
CT ID
Behavioural
Progressive Exercise After
Behavioral:
Operation of Rotator Cuff Rupture Progressive exercise
and Anterior Labrum Rupture
RCT, efficacy study
NCT00624117
Conditions
Rotator Cuff
Disease; Shoulder
Joint
95
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt May-06 Feb-10 Jyväskylä
Central Hospital
Device
Long-term Clinical Effectiveness of Device: Delta Xtend
the Delta Xtend Reverse Total
Reverse Total
Shoulder
Shoulder
study
NCT00737087
RSP® Prospective Multi-Center
Study
study
NCT01005446
Prospective Study for Safety and
Efficacy of SpaceGuard™ in
Rotator Cuff Tear Subjects
NCT00916994
Outcomes in Rotator Cuff Repair
Using Graft Reinforcement
NCT01025037
Post-Operative Quality of Life
Evaluation for Different Anesthesia
Techniques for Arthroscopic
Shoulder Surgery
RCT, efficacy study
NCT01355757
Effectiveness of the Ivivi Torino II,
Pulsed Radio Frequency Device,
on Narcotic Use, Pain and Quality
of Life Following Shoulder
Arthroscopic Rotator Cuff Repair.
NCT01507818
Cuff Tear
Arthropathy;
Osteoarthritis With
Cuff Deficiency;
Post Traumatic
Injury to Shoulder;
Revision Surgery of
a Failed Anatomic
Shoulder Prosthesis
Device: Encore
Rotator Cuff
Reverse Shoulder
Deficiency; Shoulder
Prosthesis (RSP®) Arthropathy; Failed
Shoulder
Replacement
Device: SpaceGuard Rotator Cuff Tear
Balloon
Rec
250
Adt Oct-07 Mar-19 DePuy
Sen
International
Rec
224
Adt Dec-09 Jan-18 Encore Medical, http://ClinicalTrials.gov/show/NCT01005446
Sen
L.P.
Rec
70
Adt
Sen
Device: Conexa
Reconstructive
Tissue Matrix
Rotator Cuff Tear
Rec
65
Adt Oct-09 Oct-13 Tornier; LifeCell http://ClinicalTrials.gov/show/NCT01025037
Sen
Device: Baxter
INFUSOR System
Rotator Cuff Injury
Not yet 100
Rec
Device: Ivivi Torino
II; Device: Inactive
Sham device
Rotator Cuff Tear
Adt Jun-11 Jun-12 St. Luke'shttp://ClinicalTrials.gov/show/NCT01355757
Sen
Roosevelt
Hospital Center;
Baxter
Healthcare
Corporation
Adt Dec-11 May-12 Amp
Sen
Orthopedics, Inc.
Rec
102
96
Jul-09 Dec-14 BioProtect
Rotator Cuff Repair (RCR) With
and Without OrthoADAPT
Augmentation
efficacy study
NCT00957255
Pilot Study of Augment Rotator
Cuff for Surgical Treatment of Full
Thickness Rotator Cuff Tears
Phase I: RCT, safety study
NCT01256242
Use of Graft Jacket for Rotator
Cuff Repair
study
NCT00456781
The Influence of Growth Factors
(PDGF), Applied as Autologous
Thrombocyte Concentrate, on
Functional Recovery
NCT01510639
A Safety Study Of BMP-655/ACS
As An Adjuvant Therapy For
Treatment Of Rotator Cuff Tears
NCT01122498
Plasma Glucose Levels With
Dexamethasone as Adjuvant to
Interscalene Block
Phase III: RCT,
NCT01538459
Device:
Rotator Cuff Tear
OrthoADAPT;
Procedure: Standard
of care
Term
90
Adt Mar-09 Jan-12 Synovis Surgical http://ClinicalTrials.gov/show/NCT00957255
Sen
Innovations
Device: Augment
Full Thickness
Rotator Cuff;
Rotator Cuff Tear
Procedure: Standard
Suture Repair
Active,
NR
30
Adt Nov-10 Dec-11 BioMimetic
Sen
Therapeutics
Device:
Augmentation;
Procedure: Rotator
Cuff Repair without
augmentation
Rotator Cuff Tear
Active,
NR
160
Adt Apr-07 Jul-10 Fowler Kennedy http://ClinicalTrials.gov/show/NCT00456781
Sen
Sport Medicine
Clinic; Wright
Medical
Technology
Biological: Platelet
Rich Plasma
Rotator Cuff
Rupture;
Subacromial
Impingement
Rec
104
Adt
Sen
Biological: BMP655/ACS+Standard
of care or Standard
of care; Biological:
BMP655/ACS+Standard
of care or Standard
of care; Biological:
BMP655/ACS+Standard
of care or Standard
of care
Drug:
Dexamethasone;
Drug: Bupivacaine
Rotator Cuff Tear
Active,
NR
42
Adt Jun-10 Apr-13 Pfizer
Sen
Shoulder Pain; Injury Not yet 100
of Shoulder Region;
Rec
Disorder of
Shoulder; Disorder
of Rotator Cuff;
Disorder of Tendon
of Biceps
97
Jul-10 Dec-13 St. Antonius
Hospital
Adt Apr-12 Apr-13 Lifespan; Tufts http://ClinicalTrials.gov/show/NCT01538459
Sen
Medical Center;
United States
Naval Medical
Center,
Portsmouth
Ropivacaine Block Alone or With
Perineural or Systemic
Dexamethasone for Pain in
Shoulder Surgery
NCT01450007
Platelet rich plasma and rotator
cuff tendons
RCT
ISRCTN10464365
Drug: Ropivacaine;
Drug:
Dexamethasone;
Drug:
Dexamethasone;
Drug: Normal saline;
Drug: Normal saline
Subacromial
decompression;
Subacromial
decompression and
platelet-rich plasma
Biological: Plateletrich plasma (PRP)
therapy
Interscalene
Not yet 120
Blockade in Elective
Rec
Arthroscopic Rotator
Cuff Repair
Adt Nov-11 Feb-13 Mayo Clinic
Sen
Rotator cuff
impingement and
tears
Platelet-Rich Plasma Therapy for
Shoulder Pain;
Shoulder Pain in Persons With
Rotator Cuff
Spinal Cord Injury
Tendinitis; Rotator
Cuff Syndrome;
Spinal Cord Injury
study
NCT01355549
Treatment of the Rotator Cuff
Biological: platelet
Subacromial
Disease With Platelet Rich Plasma rich plasma injection; Impingement
Injection
Drug: corticosteroid Syndrome; Partial
RCT, efficacy study
injection
Thickness Rotator
NCT01123889
Cuff Tear
The use of platelet-leukocyte
Arthroscopic rotator Large Rotator cuff
membrane in arthroscopic repair of cuff repair ± platelet- tear
large rotator cuff tear
leukocyte membrane
RCT
ISRCTN93082180
Hyaluronic acid versus
Hyaluronic acid;
Subacromial
corticosteroids compared to a
corticosteroids;
impingement
placebo in subacromial injections placebo
syndrome.
for shoulder cuff impingement
RCT, efficacy study
ISRCTN51511455
Post-Op Rotator Cuff Pain Study Drug: 0.5%
Rotator Cuff Tear
With Subacromial Bupivacaine
bupivacaine; Drug:
Infusion
Normal Saline
RCT, efficacy study
NCT01126593
Active
34
Adt Oct-10 Sep-12 University of
Sen
Oxford (UK)
Rec
6
Adt May-11 Jul-12 Kessler
Foundation
Comp
12
Adt May-10 May-11 Loma Linda
Sen
University
Comp
80
Comp
159
Adt May-08 Oct-10 Orthopaedic
Sen
Clinic University
of Rome
"Sapienza"
(Italy)
Adt Oct-04 Mar-10 Care and Public
Sen
Health Research
Institute
(CAPHRI) (The
Netherlands)
Comp
89
98
Adt Dec-08 Feb-10 Orlando Health, http://ClinicalTrials.gov/show/NCT01126593
Sen
Inc.
Procedure
Early Mobilization Following
Arthroscopic Rotator Cuff Repair
NCT01333527
Latissimus Dorsi Tendon Transfer
or Partial Arthroscopic Repair of
Massive Rotator Cuff Tears
RCT
NCT01481480
United Kingdom Rotator Cuff Trial
RCT
ISRCTN97804283
Comparison of Tendon Repair and
Physiotherapy in the Treatment of
Small and Medium-sized Tears of
the Rotator Cuff
RCT
NCT00852657
Incidence of Brachial Plexus Injury
After Rotator Cuff Repair With
Continuous Interscalene Block
RCT, safety study
NCT01334632
With Platelet-Rich Plasma (PRP)
in Medium to Large Rotator Cuff
Tears
RCT, efficacy study
NCT01458665
Procedure: No Sling; Rotator Cuff Tear
Procedure: Sling
Procedure:
Latissimus dorsi
tendon transfer;
Procedure:
Arthroscopic repair
Full Thickness
Rotator Cuff Tear
Open/mini-open
Rotator cuff tear
surgery; Arthroscopic
surgery
Procedure: Tendon Rotator Cuff Tear
repair with
acromioplasty;
Procedure:
Physiotherapy
Procedure:
Brachial Plexus
Continuous
Injury
interscalene block;
Procedure: PCA
morphine
Procedure:
Rotator Cuff Tear
Conventional
arthroscopic rotator
cuff repair;
Procedure:
Arthroscopic rotator
cuff repair with PRP
Rec
200
Not yet 108
Rec
Active
690
Active,
NR
103
Adt Apr-11 Dec-16 Shoulder &
Sen
Upper Extremity
Research Group
of Edmonton
Adt May-12 Jan-14 St. Michael's
Hospital,
Toronto;
University Health
Network,
Toronto;
Sunnybrook
Health Sciences
Centre
Adt Jul-07 Dec-13 University of
Oxford (UK)
Adt Sep-04 Dec-13 Martina
Sen
Hansen's
Hospital
Rec
120 Child Apr-11 Nov-13 Centre
Adt
Hospitalier
Sen
Universitaire
Vaudois
Rec
74
99
Adt Oct-11 Oct-13 Seoul National
Sen
University
Hospital
Subacromial impingement
syndrome and pain: a randomised
controlled trial of exercise and
injection (the SUPPORT trial)
RCT
ISRCTN42399123
Ultrasound-guided
corticosteroid
injection OR
Unguided
corticosteroid
injection WITH
EITHER
physiotherapist-led
individualised,
supervised &
progressed exercise
OR an advice &
exercise leaflet
Study of 25% Dextrose Injections Procedure: shoulder
in Shoulder Ligaments and
injections
Tendons to Promote Their Healing
RCT, efficacy study
NCT01402011
The Clinical Efficacy of Belting
Procedure:
Stabilization for Shoulder Pain
Stabilization belt;
Phase I: RCT, efficacy study
Procedure:
NCT00826293
Stabilization belt
Arthroscopic Rotator Cuff Repair Procedure:
With Platelet-Rich Plasma(PRP) in Conventional
Large to Massive Tears
arthroscopic rotator
RCT, efficacy study
cuff repair;
NCT01238302
Procedure:
cuff repair with PRP
Distal Clavicle Resection With
Procedure: distal
Rotator Cuff Repair
clavicle resection
NCT01040065
All-Arthroscopic Versus Mini-Open Procedure: AllRepair of Small or Moderate
Arthroscopic repair;
Rotator Cuff Tears
Procedure: MiniPhase III: RCT, efficacy study
open repair
NCT00128076
Subacromial
impingement
syndrome
Active
252
Adt Mar-11 Sep-13 Keele University http://www.controlledSen
(UK)
Rotator Cuff
Tendinitis
Rec
75
Adt Nov-10 Jun-13 University of
Sen
British Columbia
Rotator Cuff
Impingement
Syndrome
Invite
64
Adt
Rotator Cuff Tear
Rec
48
Adt Nov-10 Dec-12 Seoul National
Sen
University
Hospital
Acromioclavicular
Joint Arthritis
Rec
60
Child Jun-08 Mar-12 Samsung
Adt
Medical Center
Sen
Shoulder Pain;
Rotator Cuff Tear
Rec
225
Adt Aug-06 Dec-11 McMaster
Sen
University;
Canadian
Institutes of
Health
Research; The
Physicians'
Services
Incorporated
Foundation
100
Jan-09 Feb-13 Sunnybrook
Health Sciences
Centre
Types of Fixation in Arthroscopic Procedure: single
Rotator Cuff Tear
Rotator Cuff Repair
row; Procedure:
RCT, efficacy study
double row fixation
NCT00508183
Rotator Cuff Repair With
Procedure: without Shoulder Injuries
Arthroscopic Acromioplasty
acromioplasty;
(Shaving the Acromion Bone)
Procedure: with
Versus Repair Without
acromioplasty
Acromioplasty
NCT00664794
Arthroscopic Rotator Cuff Repair of Procedure:
Rotator Cuff
Full Thickness Tears With and
Acromioplasty
Syndrome; Shoulder
Without Arthroscopic
Impingement
Acromioplasty
Syndrome
RCT, efficacy study
NCT00290888
Arthroscopic Rotator Cuff Repair Procedure:
Rotator Cuff Tear
With Multimodal Analgesia(MMA) Arthroscopic rotator
RCT, efficacy study
cuff repair with
NCT01204606
intraoperative
periarticular injection;
Procedure:
cuff repair with noninjection of MMA
drugs
Accuracy of Needle Placement
Procedure: Injection Rotator Cuff
Into The Subacromial Space of
of Subacromial
Tendonitis
The Shoulder
Bursa
RCT, efficacy study
NCT01330641
Other
The Effect of Systemic or
Perineural Dexamethasone on the
Duration of Interscalene Nerve
Blocks With Ropivacaine
RCT, efficacy study
NCT01495624
Other: ropivacaine
plus dexamethasone
anesthetic; Other:
ropivacaine plus
saline plus
dexamethasone
anesthetic
Duration of
Interscalene Block;
Rotator cuff repair or
subacromial
decompressio
Comp
80
Child Apr-07 Jul-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00508183
Adt
Research
Sen
Institute
Comp
48
Adt Oct-06 Apr-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00664794
Sen
Research
Institute
Comp
86
Adt Apr-04 Mar-11 Panam Clinic
Sen
Comp
54
Adt Sep-10 Mar-11 Seoul National
Sen
University
Hospital
Comp
75
Adt Sep-08 Mar-11 University of
Sen
California, Davis
Rec
438
Adt Dec-11 Jan-15 The Cleveland
Sen
Clinic
101
Does Autologous Conditioned
Plasma Enhance Rotator Cuff
Tendon Healing After Surgery?
Phase III: RCT
NCT01414764
Impact of Autologous Platelet Rich
Plasma on Healing of Rotator Cuff
Repairs
study
NCT01000935
Other: Autologous
Supraspinatus Tear
conditioned plasma
(ACP); Drug:
Placebo
Invite
60
Adt May-11 Apr-13 The University of http://ClinicalTrials.gov/show/NCT01414764
Sen
Western
Australia;
Arthrex, Inc.
Other: Platelet Rich Rotator Cuff
Plasma; Other:
Pathology
Platelet Rich plasma
Rec
80
Other: Platelet rich
plasma
Rec
40
Adt Mar-11 Mar-13 Sunnybrook
Sen
Health Sciences
Centre; Hand
and Upper Limb
Clinic, Canada;
St. Joseph's
Health Care
London
Adt Sep-08 Sep-12 University of Sao http://ClinicalTrials.gov/show/NCT01029574
Sen
Paulo;
Criogenesis
Platelet Rich Plasma on Rotator
Cuff Repair
NCT01029574
Arthroscopic Surgical Outcome
Study In Subjects With Rotator
Cuff Tears
Phase I: Prospective, cohort
study
NCT00739947
Post-op Rehabilitation's Influence
on Tendon Healing & Clinical
Outcomes Following Arthroscopic
Rotator Cuff Repair
NCT00756015
Rotator Cuff Lesions
Other: Observational Rotator Cuff;
Comp
study of the surgical Arthroscopic Surgery
outcome
162
Adt Oct-08 Jul-11 Pfizer
Sen
Other: Early Motion
Protocol; Other:
Immobilization
Results of Rotator Cuff Repair
Retrospective, case control
study
NCT01549912
Features to Predict Success With
Nonoperative Treatment of
Patients With Rotator Cuff Tears
NCT00762580
Rotator Cuff Tear
Invite
140
Adt Nov-07 Dec-10 Washington
University
School of
Medicine;
Barnes-Jewish
Hospital
Foundation
Acute Shoulder
Dislocation
Invite
40
Adt Feb-12 Feb-15 University of
Sen
Utah
Active,
NR
380
Adt Jan-06 Jan-14 Vanderbilt
Sen
University (US)
Rotator Cuff Tear
102
Validation of the Western Ontario
Rotator Cuff Index in Patients With
NCT01532492
Results of Shoulder Arthroscopic
Surgery for Rotator Cuff, Biceps
Tendon, Labrum and Capsule
Retrospective study
NCT01401738
Functional Outcomes Following
Shoulder Surgery: A Prospective
Database
Prospective study
NCT00253864
The Effects of Platelet Rich
Plasma on the Integrity of Rotator
Cuff Repair
NCT01424969
Assessment of Muscle Function
and Size in Older Adults With
Rotator Cuff Tear
NCT01459536
Follow Up Study of Tear in the
Rotator Culf
Cross-sectional, case-crossover
study
NCT00589433
Analysis of Proinflammatory
Factors in the Synovial Fluid In
Patients With Rotator Cuff Disease
NCT01069224
Outcomes After Repair of Acute
Rotator Cuff Tears
NCT01140230
Rotator Cuff Lesion;
Disorder of Rotator
Cuff; Other
Instability, Shoulder
Rec
90
Adt Nov-11 Jun-13 St. Antonius
Sen
Hospital
Shoulder
Active,
Arthroscopic Surgery NR
170
Adt May-11 May-13 Taipei Medical
Sen
University
WanFang
Hospital
Rotator Cuff Tear;
Osteoarthritis;
Shoulder Instability
2500 Adt Nov-04 Jan-13 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00253864
Sen
Research
Institute
Rec
Rotator Cuff Tear
Arthropathy
Active,
NR
50
Sen
Utah
Rotator Cuff Tear
Rec
50
Adt Sep-11 Feb-12 Wake Forest
Sen
University
Rotator Culf Tear
Not yet
Rec
50
Adt
Jun-11 Dec-11 Hadassah
Medical
Organization
Rotator Cuff Disease Not yet
Rec
40
Adt Mar-10 Mar-11 Tel-Aviv
Sourasky
Medical Center
Rotator Cuff Tear
42
Adt Aug-09 May-10 University
Sen
Hospital,
Linkoeping
Comp
103
A5D: OTHER
Title
Interventions
CT ID
Behavioural
Biopsychosocial Factors' Influence Behavioral: pain
on Shoulder Pain
perception
NCT00187863
Device
Clinical Experience With the
Zimmer Trabecular Metal (TM)
Glenoid in Total Shoulder
Arthroplasty
RCT
NCT01539122
Humeral Resurfacing
Hemiarthroplasty
efficacy study
NCT00477360
Open-Label Study for Shoulder
Dislocation Using MG-1
study
NCT01528319
Global® AP™ Total Shoulder
Arthroplasty
efficacy study
NCT00719771
Pulsed Electromagnetic Fields
(PEMF) and Post-Axillary Surgery
Morbidity
NCT01255631
Conditions
Recruit
n
Pain Assessment
Active,
NR
350
Adt May-05 May-11 University of
Sen
Florida
Device: Zimmer TM Osteoarthritis of the
Glenoid; Device:
Shoulder
Cemented Glenoid
Not yet
Rec
80
Adt Feb-12 Feb-20 Joint
Sen
Preservation
Centre of BC
Device: Humeral
Advanced
surface replacement Glenohumeral
hemiarthroplasty
Arthritis
(CAP)
Active,
NR
30
Invite
24
Child Jan-07 Feb-13 University of
Adt
Calgary; DePuy
Sen
International;
Johnson &
Johnson
Adt Dec-11 Jan-13 Johnson &
Johnson K.K.
Medical
Company
Device: Total
Osteoarthritis
shoulder arthroplasty
(Global® AP™
Shoulder)
Rec
120
Adt Jan-08 Dec-12 DePuy
Sen
Orthopaedics
Device: PEMF
Shoulder Symptoms
Device; Device:
After Lymph Node
Sham PEMF Device Dissection
Rec
60
Adt Nov-10 Aug-12 Columbia
Sen
University; Ivivi
Health Sciences,
FLLC
only
Device: MG-1
Shoulder Dislocation
104
Age Start
(Grp) Date
End Sponsors
Date
URL
This is a 2 Year Follow up Clinical Device: Shoulder
and Radiographic Analysis of a
arthroplasty with
Novel All Polyethelene Glenoid
anchor peg glenoid
Component in Standard Total
Shoulder Arthroplasty.
study
NCT01313741
Columbia Shoulder Study (CSS) Device:
Bigliani/Flatow
Shoulder System
study
NCT01488006
Splintage In External Rotation For Current practice
Anterior Glenohumeral Dislocation: (Sling); external
A Prospective, Randomised &
rotation splint
Controlled Study
RCT
ISRCTN41070054
Conform and non conform glenoid Conform glenoid
components in total shoulder
component; nonreplacements
conform glenoid
RCT, efficacy study
component
ISRCTN42881741
ORTHOVISC Shoulder RCT
Device:
ORTHOVISC
study
NCT00436969
AA4500 for the Treatment of
Adhesive Capsulitis of the
Shoulder
study
NCT01483963
Can Parecoxib Reduce Postoperative Ipsilateral Shoulder
Pain?
study
NCT01288924
The Primary Disease Not yet 200
Process Being
Rec
Studied is Shoulder
OA and the Effect of
an All Polyethelene
Glenoid Component
on Shoulder
Arthroplasty
Adt Apr-11 Apr-12 Knoxville
Sen
Orthopedic
Clinic
Glenohumeral
Osteoarthritis
Comp
207
Adt Apr-01 Dec-11 Columbia
Sen
University;
Zimmer, Inc.
Anterior shoulder
dislocation
Comp
50
Child Nov-05 Nov-11 Department of
Adt
Health (UK)
Shoulder disorders
due to osteoarthritis
or rheumatoid
arthritis.
Comp
20
Glenohumeral
Osteoarthritis
Comp
270
N/K Nov-06 Nov-10 Leiden
University
Medical Center
(LUMC) (The
Netherlands)
Adt Dec-06 Aug-11 DePuy Mitek
Sen
Biological:
collagenase
clostridium
histolyticum; Other:
Shoulder exercises
Adhesive Capsulitis;
Frozen Shoulder
Rec
50
Adt Nov-11 Feb-13 Auxilium
Sen
Pharmaceuticals
Drug: Parecoxib;
Drug: Placebo
Shoulder Pain; Postoperative Pain
Rec
160
Adt Feb-11 Jan-13 Chiang Mai
University
105
Dexamethasone for Pain After
Shoulder Surgery
NCT01414569
Drug:
Dexamethasone
Shoulder
Impingement
Syndrome; Arthritis
Rec
75
Partial Tear of Supraspinatus
Biological: PRGF;
Partial
(SSP) and Treatment With Plasma Other: NACL
Supraspinatus Tear
Rich in Growth Factors (PRGF)
NCT01152658
Colchicine Treatment for Chronic Drug: Colchicine;
Calcific Tendonitis
Shoulder Pain Related to Calcific Drug: lactose
Tendonitis
RCT, efficacy study
NCT00983177
Oral Clonidine & Gabapentin:
Drug: Sugar pill;
Shoulder
Improving Recovery and Pain
Drug: Gabapentin; Arthroscopy; Knee
Management After Outpatient With Drug: Clonidine
Arthroscopy
Major Orthopedic Surgery
NCT01112878
A Phase 2a Study to Evaluate the Drug: AZX100 Drug Scar Prevention;
Safety and Efficacy of AZX100
Product; Drug: Saline Scar Reduction
Drug Product in Trocar Sites of
placebo
Arthroscopic Shoulder Surgery
Patients
study
NCT00811577
Pre-operative Preparation Using Drug: 2%
Post-operative
2% Chlorhexidine Cloth For
Chlorhexidine cloth Surgical Site
Shoulder Surgery
Infections
RCT, efficacy study
NCT01090479
Continuous Subacromial
Drug: bupivacaine
Shoulder
Bupivacaine
Arthroscopy
RCT, efficacy study
NCT01377415
Rec
40
Rec
80
Adt Mar-10 Oct-11 Bnai Zion
Sen
Medical Center
Invite
180
Adt Sep-09 Jun-11 Cedars-Sinai
Sen
Medical Center
Comp
153
Adt Jan-09 Dec-10 Capstone
Sen
Therapeutics
Comp
100
Adt Jan-10 Oct-10 Northwestern
Sen
University; Sage
Products
Comp
90
Adt Jan-09 Jun-10 Turku University http://ClinicalTrials.gov/show/NCT01377415
Sen
Hospital
106
Sen
Aarhus; Horsens
Hospital; Central
Denmark
Region; The
Family Hede
Nielsens Fund;
The Danish
Rheumatism
Association
Adt Apr-10 Jun-12 Meir Medical
Center
The Effect of Interscalene
Peripheral Nerve Block With
0.25% Bupivacaine vs 0.125%
Bupivacaine on Lung Function
NCT01429584
Drug: interscalene
nerve block
Diaphragm Paralysis Comp
30
Adt May-08 Feb-10 University of
Sen
Utah
Active
60
Adt Mar-12 Mar-24 Paracelsus
Medical
University
(Austria)
Active,
NR
70
Adt Mar-97 May-20 University of
Sen
Florida
Not yet
Rec
94
Adt Sep-11 Sep-18 AO Clinical
Sen
Investigation and
Documentation;
Synthes GmbH
Rec
100
Procedure: Copeland Osteoarthritis
or Global CAP
resurfacing
prosthesis
Rec
60
Adt Jun-08 Dec-17 Central Finland http://ClinicalTrials.gov/show/NCT00637013
Sen
Hospital District;
Academy of
Finland; National
Istitute For
Health and
Welfare, Finland
Sen
Aarhus
Procedure: Bankart Other Instability,
repair and
Shoulder; Hill-Sachs
remplissage;
Lesion
Procedure: Bankart
repair
Rec
150
Procedure
J-bone graft versus Latarjet
RCT
ISRCTN85886529
Latarjet procedure; J- Post-traumatic
bone graft procedure recurrent anterior
shoulder instability
with significant
glenoid defect
Arthroscopy and Manipulation vs a Procedure:
Adhesive Capsulitis
Home Therapy Program in the
Arthroscopy;
of the Shoulder
Treatment of Adhesive Capsulitis Procedure:
Arthroscopic
NCT00160784
manipulation; Other:
Home therapy
Effectiveness of Hemi- Versus
Procedure:
Osteoarthritis
Total Shoulder Arthroplasty Using Hemiarthroplasty;
Implants of the “Epoca” System" Procedure: Total
RCT, efficacy study
arthroplasty
NCT01288066
Operative Versus Non-operative Procedure: Surgery Subacromial
Management of Subacromial
(Subacromial
Impingement
Impingement
decompression);
Syndrome
RCT, efficacy study
Procedure: NonNCT00637013
operative treatment
(Physical therapy)
Comparison of Two Resurfacing
Prostheses in the Treatment of
Osteoarthritis of the Shoulder
RCT, efficacy study
NCT00408096
Arthroscopic Bankart Repair With
and Without Remplissage in
Anterior Shoulder Instability
NCT01324531
107
Adt Mar-11 Mar-15 Panam Clinic;
Sen
University of
Ottawa;
University of
Western Ontario,
Canada;
University of
British Columbia
A Comparison of Indirect and
Direct MR Arthrography of the
Shoulder Using Arthroscopic
Correlation
efficacy study
NCT01416740
Pain Management After Shoulder
Prosthesis: A Clinical Trial of
Nerve Block and Local Infiltration
RCT, efficacy study
NCT01362075
Procedure: Indirect Shoulder Pain
MRA of shoulder;
Drug: Gadopentetate
Dimeglumine
Rec
40
Adt Dec-09 Dec-13 Milton S.
Sen
Hershey Medical
Center
Procedure: Local
Pain, Postoperative
infiltration analgesia;
Procedure:
Interscalene catheter
Rec
80
Adt
Sen
New Prophylactic Maneuver: the
“Pushing” Maneuver Aiming to
Reduce the Risk for Shoulder
Dystocia"
RCT, efficacy study
NCT01297439
Comparison of Two Methods of
Subscapularis Management in
Shoulder Arthroplasty: Tenotomy
Versus Peel
RCT, efficacy study
NCT01404143
Non-operative Versus Operative
Treatment of Acute
Acromioclavicular Joint Dislocation
RCT
NCT00594841
Procedure:
suctioning of fetal
nose and mouth
during delivery;
Procedure: Pushing
maneuver
Procedure:
Subscapularis
Tenotomy;
Procedure:
subscapularis peel
Rec
80
Adt Aug-11 Aug-13 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01404143
Sen
Research
Institute
Shoulder Dystocia,;
Brachial Plexus
Injury; Asphyxia,;
Hematoma,; Clavicle
Fracture,; Humerus
Fracture.
Subscapularis Injury
Rec
Procedure: Open
Shoulder Dislocation Active,
Reduction Internal
NR
Fixation of AC joint
dislocation; Other:
Non operative
treatment of AC joint
dislocation (sling)
Jul-11 Dec-13 Horsens
Hospital;
University of
Aarhus; Aarhus
University
Hospital; The
Family Hede
Nielsens Fund;
Central Denmark
Region; The
Danish
Rheumatism
Association
3700 Adt Mar-11 Nov-13 Assistance
Publique FHôpitaux de
only
Paris
122 Child Jan-08 Jan-13 St. Michael's
Adt
Hospital,
Toronto;
Orthopaedic
Trauma
Association;
Osteosynthesis
& Trauma Care
108
Intra-articular Injection of
Allogeneic Platelet Rich Plasma
(PRP) for Adhesive Capsulitis
RCT, efficacy study
NCT01458691
Procedure: Isotonic Adhesive Capsulitis
saline injection into
the glenohumeral
joint; Procedure:
Allogenic PRP
injection into the
glenohumeral joint
SLAP Lesions; a Comparison of
Procedure: labral
SLAP Lesions
Conservative and Operative
repair; Procedure:
Treatment. A Prospective,
biceps tenodesis;
Randomized Study
Procedure:
RCT
diagnostic
NCT00586742
arthroscopy
Decreasing Upper and Shoulder Procedure:
Shoulder Pain;
Pain After Laparoscopic Surgery Pulmonary
Nausea
recruitment
study;
maneuver;
NCT01433874
Procedure:
Intraperitoneal
normal saline
infusion; Procedure:
combined group;
Procedure: Control
group
Tightrope Fixation of
Procedure: Tightrope Acromioclavicular
Acromioclavicular Joint Dislocation fixation
Joint Dislocation
- a Prospective Series
efficacy study
NCT01274884
Changes of Body Temperature
Procedure: heated Hypothermia
During Shoulder Arthroscopy
circuit; Procedure:
control
NCT01493700
Physical Therapy Versus Steroid Procedure: Manual Shoulder
Injection for Shoulder Impingement Physical Therapy;
Impingement
Syndrome
Procedure:
Syndrome
RCT, efficacy study
Corticosteroid
NCT01190891
Injection
Rec
54
Adt Nov-11 Dec-12 Seoul National
Sen
University
Hospital
Rec
120
Adt
Rec
200
Adt Feb-11 Dec-12 Taipei Veterans http://ClinicalTrials.gov/show/NCT01433874
Sen
General
Hospital,Taiwan;
FNational Yang
only
Ming University
Rec
25
Adt Mar-10 Dec-12 Sykehuset Asker http://ClinicalTrials.gov/show/NCT01274884
Sen
og Baerum
Not yet
Rec
50
Adt Dec-11 Nov-12 Gachon
University Gil
Medical Center
Rec
104
Adt May-10 Sep-12 Madigan Army http://ClinicalTrials.gov/show/NCT01190891
Sen
Medical Center;
University of
Puget Sound;
Franklin Pierce
University
109
Jan-08 Dec-12 Lovisenberg
Diakonale
Hospital
Surgery or Capsular Distention
With Steroid in the Treatment of
Primary Frozen Shoulder?
RCT
NCT01029600
Procedure:
Arthroscopic
capsular release;
Procedure:
Distention with
steroid
Adhesive Capsulitis
Rec
100
Effects of Interscalene Brachial
Plexus Nerve Blocks on the Hand
and Forearm
NCT01229683
Comparative Analysis of Intraarticular Injection of Steroid and/or
Sodium Hyaluronate in Adhesive
Capsulitis
RCT, efficacy study
NCT01144533
Procedure:
Interscalene Nerve
Block
Shoulder Surgery;
Interscalene Nerve
Block
Comp
62
Adhesive Capsulitis
Rec
60
Adt Jun-10 Dec-11 Seoul National
Sen
University
Hospital
Tenotomy;
Morselized
Osteotomy
Active,
NR
80
Adt Nov-06 Dec-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00508105
Sen
Research
Institute
Total Shoulder
Arthroplasty
Active,
NR
34
Child Aug-10 Nov-11 The Cleveland
Adt
Clinic
Sen
Procedure: isotonic
saline injection into
the glenohumeral
joint; Procedure:
steroid injection into
the glenohumeral
joint; Procedure:
sodium hyaluronate
injection into the
glenohumeral joint;
Procedure: steroid
and hyaluronate
injection into the
glenohumeral joint;
Procedure: intraarticular injection of
the glenohumeral
joint
Comparing Two Surgical Methods Procedure:
of Fixation of Subscapularis During tenotomy;
Shoulder Arthroplasty
Procedure:
RCT, efficacy study
osteotomy
NCT00508105
Patient Specific Instruments
Procedure: Glenoid
Versus Standard Surgical
Positioning System
Instruments
NCT01430468
110
Adt Dec-09 Apr-12 Bergen Surgical http://ClinicalTrials.gov/show/NCT01029600
Sen
Hospital;
Haraldsplass
Deaconess
Hospital;
Haukeland
University
Hospital
Adt Oct-10 Mar-12 University of
Sen
California, San
Diego
Followup of Glenoid Fix Utilizing
Auto Bone Graft in Shoulder
Replacement
study
NCT00670852
Subacromial Impingement - The
Need of Arthroscopic Subacromial
Decompression After Eccentric
Physical Therapy Exercises
RCT, efficacy study
NCT01037673
Arthroscopic Rotator Interval
Closure in Shoulder Instability
Repair
RCT, efficacy study
NCT00901797
Analysis of the Fixation of the
Proximal Biceps Tendon
NCT01317771
Concomitant Biceps Tenodesis in
Primary Shoulder Arthroplasty for
Primary Osteoarthritis - A
Randomised Controlled Study
RCT
ISRCTN71203361
Arthroscopic Versus Open
Stabilization for Traumatic
Shoulder Instability
RCT, efficacy study
NCT00251264
Procedure: X-rays
and CT scan
Arthritis
Procedure: Exercise Subacromial
program; Procedure: Impingement
Movement exercises Syndrome
Rec
70
Adt Apr-08 Sep-11 University of
Sen
Nebraska
Comp
102
Adt Jan-08 Jun-11 Linkoeping
Sen
University
Procedure:
Recurrent Shoulder
Arthroscopic Bankart Dislocations
repair; Procedure:
ABR+ARIC
Rec
Procedure: Open
Disorder of Tendon
proximal biceps
of Biceps
tendon tenodesis
with an EndoButton
Biceps tenodesis + Osteoarthritis
primary shoulder
arthroplasty; primary
shoulder arthroplasty
alone
Not yet
Rec
10
Adt
Comp
50
Adt Feb-06 Feb-11 Department of
Sen
Health (UK)
Procedure: Open
stabilization;
Procedure:
Arthroscopic
stabilization
Joint Instability;
Active,
Shoulder Dislocation
NR
100 Child May-09 May-11 Tel-Aviv
Adt
Sourasky
Medical Center
N/K
Mar-11 West Penn
Allegheny Health
System
194 Child Nov-01 Dec-10 University of
Adt
Calgary; Alberta
Sen
Health Services;
Calgary
Orthopaedic
Research and
Education Fund;
Canadian
Orthopaedic
Foundation
111
Reducing Shoulder Tip Pain
Following Laparoscopic Surgery
study
NCT01135836
Procedure:
Pulmonary
recruitment
maneuver;
Procedure:
Intraperitoneal
normal saline;
Procedure: Control
group
Electrothermal Arthroscopic
Procedure:
Capsulorrhaphy (ETAC) and Open Electrothermal
Inferior Capsular Shift in Patients arthroscopic
With Shoulder Instability
capsulorrhaphy
RCT, efficacy study
(ETAC); Procedure:
NCT00251160
Open inferior
capsular shift (ICS)
Other
Acromio-clavicular Dislocation
Type III - Conservative Treatment
Versus Surgical Hook Plate
Treatment
RCT, efficacy study
NCT01110304
Shoulder Pain;
Laparoscopic
Surgery
Rec
Shoulder Dislocation Comp
Other: Conservative Acromio-clavicular
treatment - brace;
Joint Dislocation
Device: Hook plate (Type III)
by Synthes
Rec
180
Adt Aug-09 Sep-10 Taipei Veterans http://ClinicalTrials.gov/show/NCT01135836
Sen
General
Hospital,Taiwan;
FNational Yang
only
Ming University
58
Child Dec-99 Feb-10 University of
Adt
Calgary;
Sen
Canadian
Institutes of
Health
Research; The
Arthritis Society,
Canada; Smith
and Nephew
(formerly Oratec
Interventions)
56
112
Adt May-07 Feb-14 Hopital de
l'Enfant-Jesus
Rehabilitation and return to work
after shoulder surgery: the
Shoulder Intervention Project
RCT
ISRCTN55768749
The effect of cost information on
patient outcomes
RCT
ISRCTN84082441
MRI Findings in Throwing
Shoulders of Waterpolo Players
assignment
NCT00959543
Occupational case Shoulder surgery
Active
management with
workplace oriented
advice (+usual
advice);
Standardised
physiotherapy with
graded exercises (+
usual advice);
Occupational case
management with
workplace oriented
advice and
standardised
physiotherapy with
graded exercises;
usual training and
advice
No information
Primary arthroscopic Comp
regarding the cost of shoulder
treatment;
decompression
Information regarding
the cost of the
surgery; Information
regarding cost of the
information specific
to the study site
Other: MRI
Waterpolo Players;
Comp
Non Throwing
Shoulders
Patient Benefit From the New
Modular Shoulder Prosthesis
PROMOS
NCT00925496
TESS Shoulder Arthroplasty Data
Collection
NCT00751673
Primary or
Secondary
Omarthrosis of the
Shoulder Joint
Shoulder
Replacement
400
Adt Nov-10 Oct-12 Danish
Ramazzini
Center
(Denmark)
180
N/K
Jul-10
45
Adt
Jul-09 Oct-10 Cantonal
Hospital of St.
Gallen
Monly
Jul-11 Imperial College http://www.controlledLondon (UK)
Rec
240
Adt Jun-09 Dec-20 Smith & Nephew http://ClinicalTrials.gov/show/NCT00925496
Sen
Orthopaedics
AG
Active,
NR
600
Adt Jan-06 Oct-20 Biomet, Inc.;
Sen
Biomet France
SARL
113
Hospital for Special Surgery
Shoulder Arthroplasty Cohort
Cohort study
NCT00527839
S.E.S Shoulder Arthroplasty Data
Collection
NCT00754416
Functional and Radiographic
Outcomes After Shoulder Surgery
Cohort study
NCT01405781
Comparison of Pain Relief After
Non Stimulating Interscalene
Catheter Placement vs Stimulating
Catheter Placement in Total
Shoulder Arthroplasty.
Prospective study
NCT01122732
Burden of Shoulder Disorders in
Primary Health Care
NCT01300091
Assessing Cerebral Blood Flow
Autoregulation During Surgery in
the Head-up Position
NCT01225185
Daptomycin With Rifampin for
Treatment of Staphylococcal
Prosthetic Joint Infection
NCT01144000
Shoulder
Arthroplasty
Shoulder Joint
Arthroplasty
Shoulder Pain;
Osteoarthritis of
Glenohumeral Joint;
Reverse Total
Shoulder
Arthroplasty
Pain; Shoulder;
Arthroplasty
Shoulder Pain;
Shoulder Mobility
Impairment
Patients Undergoing
Shoulder Surgery
Rec
250
Adt Apr-07 Apr-17 Hospital for
Sen
Special Surgery,
New York
Active,
NR
100
Adt Mar-03 Sep-16 Biomet, Inc.;
Sen
Biomet France
SARL
Invite
550
Sen
Utah
Rec
80
Sen
Chicago
Active,
NR
Rec
Staphylococcal
Not yet
Infections;
Rec
Prosthesis; hip, knee
and shoulder
Prosthetic Joint
Infection (PJI)
128 Child Oct-07 Aug-12 Central Finland http://ClinicalTrials.gov/show/NCT01300091
Adt
Hospital District
Sen
240
60
114
Adt
Sen
Jul-10 Jun-12 National Heart, http://ClinicalTrials.gov/show/NCT01225185
Lung, and Blood
Institute
(NHLBI);
Anesthesia
Patient Safety
Foundation
Adt Sep-10 Jun-11 Centre
Sen
Hospitalier
Universitaire
Vaudois;
University of
Lausanne
Hospitals;
Kantonsspital
Liestal;
Schulthess Klinik
NCT01144000
Staphylococcal
Not yet
Infections;
Rec
and shoulder
Prosthetic Joint
Infection (PJI)
60
Assessment of Weber Humeral
Derotational Osteotomy Using CT
Scan
NCT00358904
Validation of a Score for Shoulder
Function Evaluation Based on
Movement Analysis
Prospective study
NCT01281085
Hill Sachs
Comp
20
Shoulder Pain
Comp
16
115
Sen
Hospitalier
Universitaire
Vaudois;
University of
Lausanne
Hospitals;
Kantonsspital
Liestal;
Schulthess Klinik
Child May-06 Apr-11 University of
Adt
British Columbia
Sen
Adt Oct-10 Apr-11 Haute Ecole
Sen
Cantonale
Vaudoise de
Santé; Réseau
d'études
appliquées des
pratiques de
Santé de
Réadapation
(ré)insertion
A6. HAND & WRIST
A6A: PAEDIATRICS
Title
Interventions
CT ID
Procedure
A Comparison of Casting and
Procedure: Volar
Splinting in Pediatric Radial Buckle Splint; Procedure:
Fractures
Cast
Phase II: RCT
NCT01010347
Closed Reduction of Distal
Procedure: Distal
Forearm Fractures by Pediatric
Forearm Fracture
Emergency Medicine Physicians: Reduction
A Prospective Study
RCT, efficacy study
NCT01101607
Accuracy of common radiological
methods to diagnose scapholunar
dissociation: a prospective
diagnostic efficacy study
ISRCTN57744239
The Natural History of Congenital
Trigger Thumbs
NCT01424995
Conditions
Recruit
n
Age Start
(Grp) Date
End Sponsors
Date
URL
Distal Radial Buckle
Fractures
Comp
100 Child Dec-05 Apr-11 Washington
University
School of
Medicine
Pediatric Distal
Forearm Fractures
Comp
104 Child Apr-08 Apr-10 InMotion
Adt
Orthopaedic
Research
Center;
University of
Tennessee
Health Science
Center; Le
Bonheur
Children's
Medical Center;
Campbell Clinic
Wrist injury; Wrist
pain; Traumatic
scapholunar (SL)
dissociation
Comp
230
Congenital Trigger
Thumb;
Tenosynovitis
Invite
100 Child Dec-10 Dec-15 University of
Utah
116
Adt
Jan-09 Jan-11 Deutsche
http://www.controlledArthrose-Hilfe
e.V. (Germany)
Title
Interventions
CT ID
Behavioural
Effects of Motor Cognitive Training Behavioral: motor
on Functional Loss After
cognitive therapies
Osteoporotic Wrist Fractures
RCT, efficacy study
NCT01394809
Device
Use of Compression Glove to
Prevent Complications After Distal
Radius Fractures: a Randomized
Controlled Trial
RCT, efficacy study
NCT01118715
Compression Gloves for Distal
Radius Fracture
NCT01518179
Conditions
Osteoporotic Distal
Radius Fracture
Device: Compression Post-traumatic
glove
Carpal Tunnel
Syndrome; Complex
Regional Pain
Syndrome; Edema
Recruit
n
Age Start
(Grp) Date
Rec
36
Sen
Stuttgart;
German Federal
FMinistry of
only
Education and
Research
Rec
460
Adt Apr-10 Apr-14 J&M Shuler
Sen
Adt Mar-12 Mar-14 Clalit Health
Sen
Services;
University of
Haifa
Device: Made-toDistal Radius
Not yet 120
Measure
Fractures; Fracture
Rec
Compression Gloves of Lower End of
Radius; Colles'
Fracture; Smith's
Fracture
2.4 mm Variable Angle LCP Two- Device: Variable
Distal Radius
Rec
74
Column Volar Distal Radius
Angle Distal Radius Fractures
Plate ® (Surgery)
NCT01103297
Metaphyseal Distal Radius
Device: - locking
Metaphyseal Radius Rec
90
Fractures
anterior plate
Fractures (AO Type
RCT, efficacy study
A2, A3, C1 et C2)
NCT01156766
Safety Study on a Wood-plastic
Device: Omnicast
Composite Cast
study
NCT01340391
Distal Radius
Fracture
Invite
33
117
End Sponsors
Date
URL
Adt Jun-10 Nov-12 AO Clinical
Sen
Investigation and
Documentation
Sen
Hospital,
ClermontFerrand; Stryker
SA; Polyclinique
du Parc Rambot
Child Aug-09 Jun-11 Helsinki
Adt
University
Sen
Central Hospital
Fixation of Unstable Distal Radius Device: Micronail;
Fractures
Procedure: Volar
Plate Fixation
efficacy study
NCT00654615
Long Term Follow up of the DVR-A Device: ORIF with
Locking Plate
DVR-A locking plate
NCT01122628
Dynasplint for Distal Radius
Fracture
efficacy study
NCT01032356
Fractures and Bisphosphonates:
does osteoporosis treatment affect
fracture healing?
RCT
ISRCTN62133820
Effect of treatment with L0006CP
on the time of fracture-healing
RCT (placebo)
ISRCTN71678602
Efficacy of Baby Talcum in
Prevention of Pruritus Assosiated
With Cast
study
NCT01017315
SOLID-Effect of Risedronate
Sodium at Distal Radius in Colle's
Fracture.
study
NCT00460733
Distal Radius
Fractures
Distal Radial
Fractures Treated
With a DVR-A
Locking Plate
Device: Wrist
Distal Radius
Extension Dynasplint Fracture
Alendronic acid;
placebo
Distal radial fracture
Rec
64
Adt May-08 Apr-11 Wake Forest
Sen
University;
Wright Medical
Technology
250 Child May-10 Dec-10 Norfolk and
Adt
Norwich
Sen
University
Hospitals NHS
Foundation
Trust; De Puy;
Global
Diagnostics
Not yet 50
Adt Jan-10 Jun-10 Dynasplint
Rec
Sen
Systems, Inc.
Invite
Active
500
Edinburgh (UK) trials.com/ISRCTN62133820
L0006CP film-coated Wrist fracture
tablets; placebo
Comp
90
Adt Mar-11 Oct-11 Pierre Fabre
Sen
(France)
Drug: Baby talcum
Invite
50
Child Jul-09 Oct-11 Prince of
Adt
Songkla
Sen
University
Comp
141 Child Mar-07 Sep-11 Sanofi-Aventis;
Adt
Procter and
Sen
Gamble
Fracture Distal
Radius
Drug: Risedronate
Colles' Fracture
sodium; Drug:
Calcium & Vitamine
D3
Fonly
118
Procedure
Subcapital and Shaft Fractures of
the 5. Metacarpal
RCT, efficacy study
NCT01242982
Procedure: Closed Fracture
Rec
reduction and fixation
with 2 pins;
Procedure:
Reduction and
Plaster of Paris
Unstable Dorsally Displaced
Procedure: open
Fracture of the Distal Rec
Fractures of the Distal Radius in reduction and
Radius; Wrist
the Elderly
internal fixation with Fracture
RCT
a volar plate;
NCT01268397
Procedure: closed
reduction and plaster
treatment
Intraarticular Distal Radius
Procedure: External Dorsally Displaced
Rec
Fractures, X-fix or Volar Fixation fixation; Procedure: Intraarticular Distal
Volar plate
Radius Fractures;
NCT01035359
Age 50 - 74 for
Females or 60-74 for
Males; Low Energy
Trauma
Extraarticular Distal Radius
Procedure: External Dorsally Displaced
Rec
Fractures, X-fix or Volar Fixation fixation; Procedure: Intraarticular Distal
Volar plate
Radius Fractures;
NCT01034943
Age 50 - 74 for
Females or 60-74 for
Males; Low Energy
Trauma
Volar Locking Plate vs Fragment Procedure: Open
Distal Radius
Rec
Specific Fixation in Wrist Fractures reduction and fixation Fractures
RCT, efficacy study
with TriMed
NCT01311531
fragment-specific
system; Procedure:
Open reduction and
fixation with TriMed
volar locking plate
External fixation or volar plating for Volar plating;
Deviated distal
Active
treating deviated distal radius
external fixation
radius fracture
fracture
RCT
ISRCTN09599740
200
Jan-11 Dec-14 St. Olavs
Hospital;
Norwegian
University of
Science and
Technology
Sen Dec-09 Dec-14 Danderyd
Hospital
160
Adt Aug-09 Aug-14 Karolinska
Sen
Institutet
160
Adt Aug-09 Aug-14 Karolinska
Sen
Institutet
50
Adt Dec-10 May-14 Region Skane
Sen
72
Adt Mar-12 Mar-14 Federal
University of São trials.com/ISRCTN09599740
Paulo (Brazil)
80
119
Adt
Assessing Volar Locking Plates in Procedure: Surgical Distal Radius
Patients Under 65 With a Distal
Repair of Distal
Fracture
Radius Fracture
Radius Fracture
RCT
NCT01333371
Comparison of Three Fixation
Techniques for Displaced Distal
Radius Fractures
NCT00524719
Procedure: Open
Distal Radius
Reduction and
Fractures
Internal Fixation;
Procedure: NonSpanning External
Fixation; Procedure:
Closed Reduction
with Percutaneous
Fixation
Unstable Fractures of the Distal
Procedure: Volar
Distal Radius
Radius: Trial of Volar Plate Versus plate; Procedure:
Fractures
Dorsal Nail Plate Fixation
Dorsal nail plate
RCT, efficacy study
NCT00848263
Comparison of surgical procedures K-wire Fixation; Volar Dorsally displaced
for patients with a fracture of the locking plate
fracture of the distal
wrist
radius
RCT
ISRCTN31379280
Functional Outcome Following
Procedure: Kirschner Distal Radius
Fracture of the Distal Radius
wire fixation;
Fractures
Procedure: Volar
NCT01435070
Locking Plate fixation
Hyperbaric Oxygen Therapy in
Distal Radius Fractures: Can it
Shorten Recovery Time and
Increase Fracture Healing?
RCT, efficacy study
NCT01365780
Procedure:
Hyperbaric Oxygen
Therapy
Hyperbaric Oxygen
Therapy; Recovery
Time; Contrast
Media; Sonography
Not yet
Rec
64
Rec
324
Rec
120
Adt Feb-09 Dec-13 Sykehuset Asker http://ClinicalTrials.gov/show/NCT00848263
Sen
og Baerum
Active
390
Adt
Sen
Rec
50
Sen
Warwick;
University
Hospitals
Coventry and
Warwickshire
NHS Trust;
DePuy
International
Adt Jun-11 May-13 RWTH Aachen
Sen
University
Not yet 100
Rec
120
Adt
Apr-11 Mar-14 Hand and Upper http://ClinicalTrials.gov/show/NCT01333371
Limb Clinic,
Canada;
Canadian
Orthopaedic
Foundation
Adt Jan-07 Dec-13 McGill University http://ClinicalTrials.gov/show/NCT00524719
Sen
Health Center;
Orthopaedic
Trauma
Association
Jul-10 Dec-13 University of
Warwick (UK)
Volar Locking Plate Versus
External Fixator/Cast Fixation for
the Treatment of Distal Radius
Fractures
RCT, efficacy study
NCT00809861
Colles Fracture Brace prospective
randomised Study
RCT
ISRCTN45883421
CoNCReTe-trial: Colles Fractures,
Determining the Norm in Closed
Reduction Techniques
RCT, safety/efficacy study;
NCT00631267
Outcome Study of Complex Distal
Radius Fractures
Phase IV: Case-only study
NCT00160810
Procedure: volar
Distal Radius
locking plating;
Fractures
Procedure: external
immobilisation
Rec
60
Adt Aug-08 Sep-12 Mackay Base
Sen
Hospital; James
Cook University,
Queensland,
Australia
340
Adt Nov-09 May-12 NHS Grampian
Sen
(UK)
Plaster of paris
(POP) cast; Brace;
Surgery.
Colles fracture
Active
Procedure: Manual
Manipulation;
Procedure: Finger
Trap Traction
Colles' Fracture
Rec
300 Child Jul-08 May-12 Rijnstate
Adt
Hospital
Sen
Rec
120
Adt Apr-01 Apr-12 University of
Sen
Florida
Term
6
Adt Feb-11 Jan-12 Mayo Clinic
Sen
Comp
68
Adt Oct-10 Oct-11 Barnsley
Hospital NHS
Foundation Trust
(UK)
Procedure: ORIF
All Distal Radius
with a Volar Fixed
Fractures
Angled Plate;
Procedure: ORIF
with Distal Radius
Volar (DRV) Plate;
Procedure: External
Fixation
WRx Distal Radius Wrist Fracture Procedure: Surgical Wrist Fracture
Study
treatment of distal
RCT, efficacy study
radius fractures
NCT01293227
Ultrasound guided supraclavicular Intravenous regional Closed fracture of
brachial plexus block versus
anaesthesia;
the distal third of the
intravenous regional anaesthesia Supraclavicular
radius
for the manipulation of fractures of brachial plexus block
the distal radius
RCT, efficacy study
ISRCTN08332539
Osteoporosis and Colles Fracture Procedure: DEXA
Previous or Actual
Retrospective
scan
Colles Fracture
NCT00225004
Term
5000 Adt
Sen
Fonly
121
Jul-04 Aug-11 Northern
Orthopaedic
Division,
Denmark
Exploration of Wrist Soft Tissue
Injuries Associated With Wrist
Fractures
NCT01145716
Conservative Versus Operative
Treatment of Displaced Neck
Fractures of the Fifth Metacarpal
RCT
NCT00704002
Procedure:
Triangular
Arthroscopy, surgery Fibrocartilage
Complex Injuries
Procedure:
antegrade
intramedullary
splinting; Procedure:
conservative
treatment
A Randomized Controlled Trial of Procedure:
the Treatment of Mallet Fractures Biodegradable
RCT, efficacy study
Meniscus Arrow®;
NCT01232426
Device: Mallet splint
Comparison of Two Methods for Procedure:
Treatment of CollesÂ´s Fracture Osteosynthesis
RCT
NCT00609479
Range of Motion and Patients With Procedure: Physical
Distal Radius Fractures
therapy; Procedure:
RCT, efficacy study
Physical Therapy
NCT00816998
Other
Early Motion After Volar Fixation
for Distal Radius Fractures
NCT00955734
Vestibular Rehabilitation for
Patients With Fall-related Wrist
Fractures
RCT, efficacy study
NCT00988572
Contribution of ESAOTE™ Low
Field MRI for Diagnosis of
Scaphoid Fractures
efficacy study
NCT01235806
Comp
20
Adt Aug-09 May-11 Linkoeping
University
Fifth Metacarpal
Neck Fracture
Rec
80
Adt Dec-06 Dec-10 Heinrich-Heine
Sen
University,
Duesseldorf
Mallet Fracture
Active,
NR
84
Adt
Sen
Distal Radius
Fracture; ColleÂ´s
Fracture
Comp
60
Adt Jan-08 Feb-10 University of
Sen
Aarhus
Radius Fractures
Comp
39
Adt Oct-06 Feb-10 Mayo Clinic;
Sen
DePuy
Orthopaedics
Invite
80
Adt Jun-09 Jun-12 Washington
Sen
University
School of
Medicine
Adt Mar-09 Mar-12 Lund University http://ClinicalTrials.gov/show/NCT00988572
Sen
Other: Early motion; Radius Fracture
Other: Immobilization
Other: Vestibular
rehabilitation
Wrist Fractures;
Dizziness
Rec
100
Radiation: MRI
Scaphoid Bone
Fracture Suspicion
Rec
50
122
N/K
Oct-10 Conmed
Linvatec
Benelux
Adt Mar-09 Jan-12 Centre
Sen
Hospitalier
Universitaire de
Nice
Mirror Therapy and Hand
Rehabilitation
RCT
NCT01503762
Other: Mirror
therapy; Other:
Classical
rehabilitation
techniques
Distal Radius Fracture Prospective
Database 50-80 Years Old
NCT01497080
Volar Locked Plating Versus
Bridging External Fixation
NCT01062997
Swelling or Malrotation of
Metacarpal Shaft Fractures in the
Evaluation of Rotational Deformity
NCT00934869
The Treatment and Intra-operative
Imaging of Scaphoid Fracture
Reduction and Fixation
NCT01249898
Comparison of Occupational
Therapy and Home Exercises for
Adults With Operatively Treated
Distal Radius Fractures
NCT00438750
The Influence of Local Bone Status
on Complications After Surgical
Treatment of Distal Radius
Fractures
study
NCT01144208
Hand Fractures
Comp
23
Radius Fracture
Distal
Not yet 195
Rec
Adt
Jan-09 Dec-11 Ahvaz
Jundishapur
University of
Medical
Sciences
Adt Jan-12 Jan-15 Lawson Health
Sen
Research
Institute
Distal Radius
Fracture
Rec
140
Metacarpal Shaft
Fractures
Rec
N/K
Scaphoid Fractures
Rec
N/K
Adt
Sen
Distal Radius
Fractures
Active,
NR
60
Adt Aug-06 Feb-11 Massachusetts http://ClinicalTrials.gov/show/NCT00438750
Sen
General Hospital
Distal Radius
Fractures; Poor
Bone Quality;
Treatment
Complications
Comp
244
Adt Feb-07 Apr-10 AO Clinical
Sen
Investigation and
Documentation
123
Adt Sep-09 Mar-14 University
Sen
Hospital,
Akershus;
University of
Oslo; Haukeland
University
Hospital
Adt Aug-09 Dec-11 Hadassah
Sen
Medical
Organization
N/K
Aug-11 Hadassah
Medical
Organization
A6C: OTHER
Title
CT ID
Behavioural
Early Motion Following Carpal
Tunnel Release
RCT, efficacy study
NCT00845325
Device
Ascension® MCP Post-Approval
Study
NCT01398735
Interventions
Conditions
Behavioral: early
motion; Behavioral:
Control group
Carpal Tunnel
Syndrome
Recruit
Rec
Device: Ascension Rheumatoid Arthritis; Rec
MCP Finger Implant Systemic Lupus
Erythematosus;
Osteoarthritis; Posttraumatic Arthritis
Dupuytren's Disease and
Device: Intervention - Dupuytren
Rec
Extracorporeal Shockwave
ESWT Storz Duolith Contracture
Therapy (DupuyShock-2010)
high energy; Device:
CONTROL SHAMNCT01184586
ESWT Storz Duolith
[0.01mJ/mm2]
Evaluation of the MANOS Carpal Device: MANOS
Carpal Tunnel
Invite
Tunnel Release System in Patients CTR™
Syndrome
With Carpal Tunnel Syndrome
NCT01450735
IMS-treatment and Canalis Carpi Device: Needle in
Carpal Tunnel
Comp
Syndrome
acupuncture point
Syndrome
RCT, bio-equivalence study
Li11; Device: IMS of
NCT01102868
the musculus
pronator teres
Using HandTutor With Traumatic Device: HandTutor Hand Injuries.
Rec
Hand Injuries: Characterizing the System
System
assignment
NCT01210833
n
Age Start
(Grp) Date
End Sponsors
Date
100 Child Dec-08 Dec-11 University of
Adt
MissouriSen
Columbia
URL
100
Adt Feb-02 Dec-13 Ascension
Sen
Orthopedics, Inc.
60
Adt Nov-11 Dec-12 Hannover
Sen
Medical School
100
Adt Oct-11 Sep-12 Thayer
Sen
Intellectual
Property, Inc.
75
Adt Apr-09 Jan-12 UNIFOB A/S
Sen
40
Adult Oct-10 Dec-11 Meir Medical
Center
124
Adaprev in Digital Flexor Tendon Device: Adaprev
Tendon Injuries
Repair
NCT01014494
Prospective clinical trial comparing C-Trac™ splint;
Carpal tunnel
C-Trac™ splint with conventional Conventional resting syndrome
resting splint for treatment of
splint
carpal tunnel syndrome
Effect of orthoses in hand
Prefabricated
Osteoarthritis of the
osteoarthritis
orthosis + Exercise; carpometacarpal
RCT
Exercise only
joint
ISRCTN40357804
An RSA and DEXA Study on
Device: Avanta (PIP Osteoarthritis
Migration of Proximal
joint implant with a
Interphalangeal (PIP) Joint
titanium porous
Prostheses of the Hand
coating)
NCT00175188
Splinting after Contracture Release Surgery for
Dupuytren’s
for Dupuytren's
contracture release + Contracture
RCT
usual post-operative
ISRCT57079614
hand therapy ± static
night splint
Rec
44
Adt Sep-09 Dec-11 Renovo
Sen
Comp
50
Adt
Comp
60
Adt Nov-08 Dec-10 Diakonhjemmet http://www.controlledSen
Hospital
(Norway)
Comp
30
Adt Jun-04 Oct-10 University of
Sen
Aarhus; Aarhus
University
Hospital; Biomet,
Inc.; Avanta
Comp
128
Adt Oct-07 Apr-10 University of
East Anglia (UK) trials.com/ISRCTN57079614
Post Approval Commitment Study Drug: Xiapex;
Dupuytren's
Not yet
Phase IV: Prospective study
Procedure: surgery Contracture
Rec
NCT01444729
Assessment of Efficacy and Safety Drug: co.don
Large Articular
Rec
of 3 Different Doses of co.Don
chondrosphere®
Cartilage Lesions of
Chondrosphere to Treat Large
the Femoral;
Cartilage Defects
Condyle, Trochlea,
Tibia or Retropatellar
study
NCT01225575
Injectable Collagenase and
Drug: Xiapex;
Dupuytrens
Rec
Percutaneous Needle Fasciotomy Procedure:
Contracture
for Dupuytren's Contracture
Percutaneous needle
fasciotomy
NCT01538017
Jun-06 Jun-11 Derby Hospitals http://www.controlledNHS Foundation trials.com/ISRCTN26618585
Trust (UK)
0
Adt Jan-12 Mar-18 Pfizer
Sen
75
Adt
50
Adt Feb-12 Jan-15 Jeppe Lange,
Sen
MD
125
Oct-10 Jul-16 co.don AG
Botulism Toxin Injection as a
Treatment for Arthritis of the Basal
Thumb Joint
study
NCT01045694
Drug: Botulinum
Toxin Type A; Drug:
Triamcinolone
Acetonide; Drug:
Lidocaine
Basilar Joint
Rec
45
Arthritis; Basal
Thumb Joint
Arthritis;
Trapeziometacarpal
Arthritis;
Carpometacarpal
Arthritis
Biological: XIAFLEX / Dupuytren's Disease Not yet 100
XIAPEX
Rec
Retreatment of Recurrent
Dupuytren's Contractures
study
NCT01498640
Study of PXL01 Versus Placebo to Drug: PXL01; Drug: Surgical Adhesions
Inhibit Adhesion Formation After Placebo
Flexor Tendon Surgery
study
NCT01022242
Administration of Two Injections for Biological: AA4500 Dupuytren's
Multiple Dupuytren's Contractures collagenase
Contracture
clostridium
histolyticum
study
NCT01407068
Steroid Injection Treatment of
Drug:
Carpal Tunnel
Carpal Tunnel Syndrome
Methylprednisolone Syndrome
Phase II/III: RCT, safety/efficacy 40 mg; Drug:
study
Methylprednisolone
NCT00806871
80 mg; Drug: Sodium
chloride
The effect of dexmedetomidine in Levobupivacaine + Forearm and hand
addition to local anaesthetic on the dexmedetomidine + surgery patients
block of nerves in the arm
isotonic sodium
RCT
chloride;
ISRCTN67622282
Levobupivacaine +
isotonic sodium
chloride
Rec
Adt Mar-11 Nov-13 University of
Sen
MissouriColumbia
Adt Mar-12 Sep-13 Auxilium
Sen
Pharmaceuticals
138 Child Dec-09 Jun-12 PharmaSurgics http://ClinicalTrials.gov/show/NCT01022242
Adt
AB
Active,
NR
60
Adt Sep-11 Apr-12 Auxilium
Sen
Pharmaceuticals
Rec
120
Adt Nov-08 Mar-12 Region Skane
Sen
Comp
64
Adt Nov-11 Feb-12 Cumhuriyet
Sen
University
(Turkey)
126
MRI Results in Dupuytren's
Biological: XIAFLEX Dupuytren's Disease Active,
Contracture Before and After
NR
Injection With Xiaflex
assignment
NCT01450397
Study Comparing One Versus Two Drug: One cortisone Stenosing
Rec
Cortisone Injections for Trigger
injection; Drug: Two Tenosynovitis;
Finger
cortisone Injections Trigger Finger
Parallel assignment, efficacy
study
NCT00951236
ED95 bupivacaine and
Bupivacaine for
Routine hand,
Comp
supraclavicular block
supraclavicular
forearm or upper
brachial plexus block limb surgery
ISRCTN63230740
A Study of Hyaluronan for the
Drug: Synvisc (Hylan Osteoarthritis
Rec
Treatment of Osteoarthritis in the G-F20; hyaluronan
Thumb
injection); Drug:
Phase III: RCT
Bupivicaine (local
NCT00398866
anesthesia injection);
Drug: Kenalog
(triamcinolone;
corticosteroid
injection)
Procedure
Hand Transplantation for the
Procedure: Hand
Amputation;
Reconstruction of Below the Elbow transplantation
Transplantation
Amputations
NCT00778856
Follow-up of Patients After 4-row Procedure:
Wrist Surgery
Arthrodesis or Proximal Row
Anamnesis and
Carpectomy
clinical examination
efficacy study
NCT00284310
5
Adt Mar-11 Feb-12 Scott Wolfe;
Sen
Auxilium
Pharmaceuticals
, Inc
392
Adt May-09 Nov-11 Rothman
Sen
Institute
Orthopaedics
40
Sen
Leeds (UK)
213
Adt Aug-06 Aug-10 Hospital for
Sen
Special Surgery,
New York;
Genzyme
Rec
5
Adt Sep-08 Dec-22 Emory University http://ClinicalTrials.gov/show/NCT00778856
Rec
40
Sen
Hospital, Ghent
127
Human Upper Extremity
Allotransplantation
NCT00722280
Allograft Meniscal Arthroplasty for
the Treatment of Basal Joint
Arthritis of the Thumb
NCT01542515
Allogeneic Hand Transplantation
Composite Tissue
Allotransplantation
NCT00711373
Procedure: Hand
Transplantation
Hand Transplantation for
Treatment of Dominant Hand or
Bilateral Hand Amputees
NCT01293214
Open Surgery Versus
Corticosteroid Injections in
Treatment of Trigger Finger
RCT, efficacy study
NCT01486420
Suture Fixation System Versus
Tendonous Reconstruction in
Carpometacarpal (CMC)
Arthroplasty
RCT, efficacy study
NCT01121874
Procedure: Hand
transplantation
Procedure:
Corticosteroid
injections;
Procedure: Open
surgery
Procedure: Ligament
reconstruction with
suture fixation
system; Procedure:
Ligament
Reconstruction with
Tendon Interposition
Amputation,
Traumatic
Invite
300
Pittsburgh
Active,
NR
20
Adt Mar-09 Sep-16 William
Sen
Beaumont
Hospitals;
LifeNet Health
Rec
10
Adt
Upper Extremity
Amputation; Hand
Amputation
Rec
10
Trigger Finger
Rec
166
Adt Jan-12 Jan-15 Jeppe Lange,
Sen
MD
Thumb
Carpometacarpal
Arthritis
Rec
60
Adt Apr-10 Apr-14 J&M Shuler
Sen
Procedure: Meniscal Arthritis
allograft arthroplasty
of the
carpometacarpal
joint of the thumb
Procedure:
Upper Extremity
Allogeneic hand
Injuries; Amputation
transplantation
128
Jun-98 Jun-15 Christina L.
Kaufman PhD;
Jewish Hospital
and St. Mary's
Healthcare;
Kleinert, Kutz
and Associates;
University of
Louisville; U.S.
Army Medical
Research and
Materiel
Command;
Department of
Defense
Adt Feb-10 Feb-15 Brigham and
Women's
Hospital
The Effects of a Stainless Steel
Procedure: Stainless Zone 2 Flexor
Not yet 24
Adt
Suture MGH Flexor Tendon Repair steel suture;
Tendon Lacerations
Rec
Sen
Coupled With Early Aggressive
Procedure:
of the Hand
Range of Motion Rehabilitation: a Polypropylene
Randomized Controlled Trial
suture; Behavioral:
Aggressive early
study
active range of
NCT01344980
motion rehabilitation;
Behavioral: Early
active range of
motion rehabilitation
Prevention of Phantom Limb and Procedure:
Amputation;
Active, 18
Adt
Stump Pain Using Ambulatory
perineural ropivicaine Phantom Limb Pain;
NR
Sen
Continuous Peripheral Nerve
Stump Pain
Blocks
study
NCT00771862
Axillary Plexus Block in a High
Procedure: Axillary Nerve Block;
Invite
45
Adt
Resolution MRI
plexus block and
Magnetic
Sen
Phase II: RCT, efficacy
MRI
Resonance Imaging
studyNCT01033006
Vascularized Versus NonProcedure:
Scaphoid NonRec
40
Adt
Vascularized Bone Grafts in
Vascularized Bone Unions
Sen
Treating Proximal Pole Scaphoid Graft; Procedure:
Non Unions
Non-Vascularized
RCT, efficacy study
Bone Graft
NCT01419808
PRCT: Comparing Ligament
Procedure: LRTI;
Joint Disease
Rec
130 Adt
Reconstruction and Tendon
Procedure:
Sen
Interposition (LRTI) With a Joint
Ascension PyroDisk
Spacer for Trapeziometacarpal
(TMC) Osteoarthritis (OA)
(TMC/PyroDisk Study)
RCT, efficacy study
NCT00671333
Traumatic Ulnar Translocation of Procedure: Surgery Traumatic Ulnar
Comp 10 Child
the Carpus
or immobilization
Translocation of the
Adt
Carpus
Sen
NCT01258166
129
Jun-11 Jun-13 University of
Manitoba
Oct-08 Dec-12 University of
California, San
Diego; National
Institute of
General Medical
Sciences
(NIGMS)
Jan-09 Oct-12 Diakonhjemmet http://ClinicalTrials.gov/show/NCT01033006
Hospital; Oslo
University
Hospital
Sep-07 Jul-12 Hand and Upper http://ClinicalTrials.gov/show/NCT01419808
Limb Clinic,
Canada
Apr-08 Apr-12 Simon Fraser
Orthopaedic
Fund
Jan-05 Jan-12 Northwestern
University
Ambulatory Continuous Peripheral Procedure:
Nerve Blocks for Treatment of
perineural
Post-Amputation Phantom Limb
ropivacaine
and Stump Pain
RCT, efficacy study
NCT00667264
Proximal Interphalangeal Joint
Arthroplasty Using a Graft From
the Capitate
study
NCT01479738
Hypoalgesic and motor effects of
Kaltenborn mobilization on elderly
patients with secondary thumb
carpometacarpal osteoarthritis
RCT
ISRCTN06361999
Surgical Versus Conservative
Treatment of Acute Mallet Fingers;
a Randomised Controlled Trial
RCT, efficacy study
NCT01016197
Post-operative Mobilization for
Carpal Tunnel Syndrome
RCT
NCT00435149
Comp
7
Procedure: Capitate Recurrent
bone grafting
Dislocation of Hand
Comp
18
Kaltenborn’s
mobilization
technique; Placebo
Comp
26
Sen May-11 Jun-11 Azienda
http://www.controlledSanitaria Locale trials.com/ISRCTN06361999
(ASL) 3 (Italy)
Procedure: extensor Finger Injury
tendon repair
Not yet
Rec
50
Child Jan-10 Jun-11 Mid Cheshire
Adt
Hospitals NHS
Sen
Foundation Trust
Procedure: Carpal
Carpal Tunnel
tunnel release
Syndrome
surgery; Procedure:
Carpal tunnel release
surgery
Percutaneous needle Dupuytren’s disease
fasciotomy; limited
fasciectomy
Comp
100
Adt Dec-06 Feb-11 Vanderbilt
Sen
University
Comp
120
N/K Aug-02 Jan-11 University
Medical Centre
Groningen
(Netherlands)
Invite
60
Percutaneous needle fasciotomy
versus limited fasciectomy in
Dupuytren's disease
RCT
ISRCTN58554745
Carpal Tunnel Syndrome Release Procedure: Limited
Using PSU Retractor
incision using PSU
retractor
study
NCT01017471
Amputation;
Phantom Limb;
Stump Pain
Carpometacarpal
osteoarthritis
Carpal Tunnel
Syndrome
130
Adt Oct-08 Dec-11 University of
Sen
California, San
Diego; Summit
Medical;
National Institute
of General
Medical
Sciences
Adt Jan-05 Oct-11 The Second
Hospital of
Qinhuangdao
Child Sep-09 Dec-10 Prince of
Adt
Songkla
Sen
University
PRCT: Comparing Two
Procedures for Ulno-Carpal
Abutment Syndrome.
RCT, efficacy study
NCT00564980
Medial Versus Lateral Approach in
Ultrasound (US)-Guided
Supraclavicular Block
RCT, efficacy study
NCT00992810
Computer Assisted Planing of
Corrective Osteotomy for Distal
Radius Malunion
RCT
NCT01193010
Other
Postoperative Rehabilitation
Following Trapeziectomy and
Ligament Reconstruction Tendon
Interposition
NCT01425034
Long-term Observational
Evaluation of Subjects Treated
With AA4500 in Studies AUX-CC854, AUX-CC-856, AUX-CC857/AUX-CC-858 and AUX-CC859
NCT00954746
Diagnostic Accuracy of Direct MR
Arthrography Of The Wrist At 1.5,
3.0 And 7.0T
NCT01012271
The Occlusive Dressing
RCT, efficacy study
NCT01002638
Procedure: Wafer
Joint Disease
Procedure;
Procedure: Ulnar
shortening
osteotomy
Procedure: Lateral- Hand or Arm
to-Medial Approach; Surgery
Procedure: Media-toLateral Approach
Term
3
Child Jul-07 Dec-10 Simon Fraser
Adt
Orthopaedic
Sen
Fund
Rec
78
Adt Aug-09 Sep-10 University Health http://ClinicalTrials.gov/show/NCT00992810
Sen
Network,
Toronto
Procedure:
Computer-Assisted
Surgical Planning;
Procedure: distal
radius osteotomy
Rec
40
Adt Aug-10 Aug-10 Massachusetts
Sen
General
Hospital; AO
foundation
Other: casts for the Osteoarthrosis of the Invite
thumb; Other: Motion Carpometacarpal
group
Joint of the Thumb
210
Sen
Utah
Other: No
Intervention
Advanced
Dupuytren's Disease
Invite
600
Adt
Sen
Other: MRI
Wrist Injuries
Not yet
Rec
70
Sen
Zurich
Rec
100
Adt Dec-09 May-12 University
Sen
Hospital,
Strasbourg,
France
Extraarticular Distal
Radius Malunion
Other:
Fingertips Traumatic
TEGADERM®;
Amputations
Procedure: Surgery
131
Jul-09 Mar-13 Auxilium
Pharmaceuticals
Determining the Minimum Effective Other: Bupivacaine
Volume of Local Anesthetic for
0,5%
Ultrasound-guided Axillary Brachial
Plexus Block
efficacy study
NCT01421914
Corticosteroid Injection as a
Other: Corticosteroid
Predictor of Outcome in Carpal
Injection- 1ml of
Tunnel Release
Betamethasone and
1 ml of 1% Lidocaine
NCT00655915
The Role of Antibiotics After
Other: No
Surgical Treatment of Simple Hand intervention
Infections: A Prospective Study
NCT01429571
Length of Post Operative Dressing Other: extended
After Carpal Tunnel Release
postoperative
dressing; Other:
NCT01310218
short postoperative
dressing
Basal Joint Arthritis Prospective
NCT01376024
The Safety of Hand Surgery in the
Anticoagulated Patient
NCT00954928
Carpal Tunnel Release in Diabetic
Patients
NCT01201109
Axillary Brachial
Plexus Block
Active,
NR
25
Adt Dec-10 Aug-11 Federal
University of
SÃ£o Paulo
Carpal Tunnel
Syndrome
Term
200
Adt Dec-07 Mar-11 Vanderbilt
Sen
University
Hand Infections
Comp
90
Adt Aug-09 Dec-10 BG Trauma
Sen
Center
Tuebingen
Carpal Tunnel
Syndrome
Comp
96
Adt May-09 Nov-10 University of
Sen
Connecticut
Health Center
Rec
500
Adt
Sen
Invite
200
Adt
Sen
Carpal Tunnel
Invite
Syndrome; Diabetes;
Nerve Entrapment
66
Adt
Sen
Basal Joint of the
Thumb
Hand Surgery
132
Jul-06 Sep-12 Columbia
University;
Arthritis
Foundation;
American
Society for
Surgery of the
Hand
Jun-09 Jun-12 Washington
University
School of
Medicine
Nov-10 Dec-11 Skane University http://ClinicalTrials.gov/show/NCT01201109
Hospital
Medical Review: Hand Surgery
After Local Block Versus Nonblock
study
NCT01110759
Health-Related Quality of Life in
Patients With Dupuytren's Disease
Phase I: Prospective, cohort
study
NCT00468949
Orthopaedic Hand Service Data
Repository
Cohort study
NCT01393262
Splinting for Dupuytren's
Contracture Release
NCT00575458
Biomechanical Evaluation of Wrist
Ligament Injuries: Diagnostic Tool
to Detect Wrist Instability
NCT00657072
Carpal Tunnel
Syndrome
Active,
NR
200
Dupuytren's
Contracture
Comp
51
Non-traumatic and
Traumatic Health
Issues
Rec
Adt Aug-09 Jul-11 Cedars-Sinai
Sen
Medical Center
Adt May-07 Jul-11 Hamilton Health http://ClinicalTrials.gov/show/NCT00468949
Sen
Sciences
Corporation;
McMaster
University
2000 Adt Nov-09 Jul-11 Massachusetts http://ClinicalTrials.gov/show/NCT01393262
Sen
General Hospital
Dupuytren's Disease Comp
60
Adt Jun-05 Jun-10 Massachusetts http://ClinicalTrials.gov/show/NCT00575458
Sen
General Hospital
Scapholunate
Invite
Interosseous
Ligament; Torn Wrist
Ligaments
50
Child May-03 May-10 State University http://ClinicalTrials.gov/show/NCT00657072
Adt
University;
National
Institutes of
Health
133
A7. UPPER LIMB (including elbow)
A7A: PAEDIATRICS
Title
CT ID
The Post-Operative Pain
Management of Pediatric
Supracondylar Elbow Fractures
RCT, efficacy study
NCT01328782
Interventions
Conditions
Drug: Oxycodone
Elbow Fracture
with Acetaminophen;
Drug: Bupivacaine
0.25%; Drug:
Ropivacaine 0.20%
Procedure
Comparison of Tendon Transfer,
Botox Injections and Ongoing
Treatment in Hemiplegic Cerebral
Palsy
RCT, efficacy study
NCT00250081
Procedure: Upper
Cerebral Palsy
Extremity Tendon
transfer; Procedure:
Botulinum Toxin
injections in Upper
Extremity;
Procedure: Regularly
ongoing therapy
Treatment of Type I Supracondylar Procedure: Cast;
Type I
Fractures of the Humerus
Procedure: Splint;
Supracondylar
Procedure: Tape
Fracture of the
NCT00904137
Humerus
Nurse Reduction of Pulled Elbow Procedure:
Radial Head
Reduction of Radial Subluxation
NCT00993954
Head Subluxation
Other
Effect of Occupational Therapy on Other: Occupational Supracondylar
the Function and Mobility of Elbow therapy
Humerus Fracture
Fractures
RCT, efficacy study
NCT00871793
Recruit
Active,
NR
n
Age Start
(Grp) Date
End Sponsors
Date
URL
124 Child Jun-08 Jun-11 Children's
Hospital Colorad
Rec
78
Child Feb-05 Dec-12 Shriners
Hospitals for
Children
Rec
87
Child May-09 Feb-12 University of
British Columbia
Rec
224 Child Oct-09 Oct-11 Children's
Hospital of
Eastern Ontario;
Ontario Ministry
of Health and
Long Term Care
Rec
128 Child Mar-09 Sep-12 Seattle
Children's
Hospital
134
Randomized Trial of Casting
Techniques for Displaced Forearm
Fractures
RCT, efficacy study
NCT00823823
Self Cast Removal at the Child's
Home
RCT
ISRCTN55089523
Other: Bivalved cast; Displaced Forearm
Other:
Fractures
Circumferential cast
Active,
NR
224 Child Jan-09 Dec-11 Children's
Hospital Boston
Traditional plaster of Upper limb fractures
Paris or fibreglass
in children
rigid cast + fracture
clinic for removal;
Home-removable
flexible cast taken off
at home by the
parent/carer.
Comp
460 Child May08 Mar-11 Oxford Radcliffe http://www.controlledHospitals NHS trials.com/ISRCTN55089523
Trust (UK)
Type II Supracondylar Fractures in
Children
Prospective study
NCT00207870
100 Child Oct-06 Jul-11
Type II
Supracondylar
Fractures
Rec
Interventions
Conditions
Recruit
n
Device: NovaLign
Intramedullary
Fixation System
Fracture
Rec
20
Children's
Healthcare of
Atlanta
Title
CT ID
Device
NovaLign Intramedullary Fixation
System (IFS) for the Treatment of
Humeral Fractures
study
NCT00969839
135
Age Start
(Grp) Date
End Sponsors
Date
Adt Sep-09 Mar-11 NovaLign
Sen
Orthopaedics,
Inc
URL
A Dosing and Efficacy Study of
Drug: sufentanil
Intra-nasal Sufentanil for Moderate
to Severe Pain
NCT01012999
Procedure
Study Comparing Surgical
Treatment Versus Non-surgical
Treatment of Ulnar Fractures
RCT
NCT01123447
Pain; Opiate; upper
or lower extremity
fracture
Term
Procedure: Open
Fracture; Trauma;
Rec
reduction and
Ulna Fracture;
internal fixation;
Orthopedic; Surgery
Procedure: Closed
reduction and shortarm cast
Forearm Shaft Fractures: Plating Procedure:
Fractures of Radius
Rec
of Radius and Ulna Versus Plating intramedullary nailing and Ulna
of Radius and Nailing of Ulna
and plating;
RCT, efficacy study
Procedure: plating
NCT01484366
A Trial of Plate Fixation Versus
Procedure: Tension Displaced Olecranon Rec
Tension Band Wire for Olecranon Band Wiring;
Fractures
Fractures
Procedure: Plate
RCT, efficacy study
fixation
NCT01391936
A Trial of Plate Fixation Versus
Procedure: Tension Displaced Olecranon Rec
Tension Band Wire for Olecranon Band Wiring;
Fractures
Fractures
Procedure: Plate
RCT, efficacy study
fixation
NCT01391936
Conservative versus surgical
Bridging plate
Humeral shaft
Active
interventions for treatment of the osteosynthesis;
fracture
humeral shaft fractures in adults Functional brace
RCT
ISRCTN24835397
Operative and Nonoperative
Procedure: Open
Humeral Mid-shaft
Active,
Treatment of Humeral Shaft
reduction and
Fractures
NR
Fractures
internal fixation
(ORIF); Other: Nonstudy
surgical
NCT00878319
16
Adt Nov-09 Mar-11 University of
Sen
Utah
100
Adt May-10 Dec-15 University of
Sen
Calgary (UK)
90
Adt Sep-10 Sep-13 Florida
Sen
Orthopaedic
Institute
70
Child Sep-10 Sep-13 Royal Infirmary
Adt
of Edinburgh
Sen
70
Child Sep-10 Sep-13 Royal Infirmary
Adt
of Edinburgh
Sen
126
Adt
Sen
180
Adt Aug-09 May-12 McGill University http://ClinicalTrials.gov/show/NCT00878319
Sen
Health Center;
Canadian
Orthopaedic
Trauma Society
136
Jul-10 Dec-12 Federal
http://www.controlledUniversity of Sao trials.com/ISRCTN24835397
Paulo (Brazil)
Effect of Osteosynthesis, Primary Procedure: NonProximal Humeral
Rec
162 Adt Apr-09 Mar-12 Herlev Hospital
Hemi-arthroplasty, and Nonsurgical
Fractures
Sen
(Denmark)
surgical Management for Fractures management;
of the Proximal Humerus
Procedure:
Phase III: RCT
Osteosynthesis;
NCT00835562
Procedure:
Hemiarthroplasty
Open reduction and internal
Open reduction +
Comminuted,
Comp 560 Sen Sep-08 Feb-12 German
fixation versus closed reduction
internal fixation;
intraarticular distal
Research
and casting for highly comminuted, closed reduction + radial fractures
Council
intraarticular fractures of the distal casting
(Germany)
radius
RCT
ISRCTN76120052
Fluid Lavage of Open Wounds
Saline solution
Open fractures,
Comp 2280 Adt Jun-09 Jan-12 McMaster
(FLOW)
gravity pressure (1 - upper or lower
Sen
University
RCT
2 psi); Saline solution extremity
(Canada)
ISRCTN33993149
low pressure (5 - 10
psi); Saline solution
high pressure (>20
psi); Castile soap
solution (80 ml per 3
litres saline) gravity
pressure (1 - 2 psi);
Castile soap solution
low pressure (5 - 10
psi); Castile soap
solution high
pressure (>20 psi)
Clinical study of the volar locking Radial volar locking Distal radius fracture Comp 122 Child Feb-08 Aug-10 Nottingham
plate for distal radial fractures
plate; Conventional
Adt
University
RCT
method involving
Sen
Hospitals NHS
ISRCTN27396017
percutaneous wires
Trust (UK)
+/- external fixator
Management of Bone Defects
Procedure: HMRS
Tumor; Fracture;
Rec
50 Child Dec-08 Jan-10 Medical
Around the Elbow
Cancer
Adt
University of
Sen
Vienna
NCT00873145
137
Other
A Trial of Non-operative Versus
Operative Management of
Olecranon Fractures in the Elderly
RCT, efficacy study
NCT01397643
Reducing Range of Motion Deficits
Post Radial Fracture
RCT
NCT01262807
Operative Versus Non Operative
Treatment of Proximal Humerus
(Shoulder Joint) Fractures
Phase I: RCT, bio-equivalence
study
NCT00818987
Other: Nonoperative; Other:
Operative
Displaced Olecranon
Fractures in Elderly
Patients
Rec
70
Sen Oct-10 Oct-13 Royal Infirmary
of Edinburgh
Other: Exercises
Radius Fractures
Rec
70
Other: Open
reduction internal
fixation; reduction
and immobilization
3 and 4 Part
Proximal Humerus
Fractures
Rec
120
Sen
Manitoba; Pan
Am Minor Injury
Clinic
Sen Nov-10 Oct-11 University of
British Columbia
Discovery™ Elbow System
NCT00698867
Comparison of Two Radial Head
Implants
NCT01269840
Operative Versus Nonoperative
Treatment of Humeral Shaft
Fractures: A Prospective Cohort
Comparison Study
NCT01363518
Osteoarthritis;
Invite
Avascular Necrosis;
Humeral Fractures
Radial Head
Rec
Fractures
120
Adt Jun-02 Jun-15 Biomet
Sen
Orthopedics,
LLC
50
Closed Fracture of
Shaft of Humerus
128
Adt Mar-10 Jul-11 Northwestern
Sen
University; Rush
University; North
Shore University
Hospital
Adt May-10 May-11 St. Louis
University
Invite
138
A7C: OTHER
Title
CT ID
Behavioural
Eccentric Training With or Without
Elbow Brace for Epicondylitis
NCT01273688
Device
Discovery Elbow Long-Term
Survivorship
NCT01308463
Ascension's PyroCarbon Radial
Head Compared to Ascension's
Metal Radial Head
NCT00825409
Discovery Elbow Multi-Center
Prospective Study
NCT00515515
VIBration Training in EpicondylitiS
NCT01269879
ExploR® Modular Radial Head
Data Collection
Prospective study
NCT00533234
Interventions
Conditions
Behavioral: Eccentric Epicondylitis;
training (Flex-Bar); Tendinopathy; Pain
Device: EpiHit elbow
brace
Recruit
n
Not yet
Rec
90
Age Start
(Grp) Date
End Sponsors
Date
Adt Feb-11 Nov-11 Hannover
Sen
Medical School
URL
Device: Discovery
elbow minimally
constrained
Elbow Pain
Rec
120 Child Jan-10 Dec-20 Biomet, Inc.
Adt
Sen
Device: Carbon
Modular Radial
Head; Device: Metal
Radial Head
Degenerative
Arthritis; PostTraumatic Arthritis;
Rheumatoid Arthritis
Rec
203
Adt Jan-09 Jan-12 Ascension
Sen
Orthopedics, Inc.
Device: Discovery
Elbow replacement
Total Elbow
Arthroplasty
Wdrwn
40
Adt May-07 Dec-11 Vanderbilt
Sen
University;
Biomet, Inc.
Not yet
Rec
70
Adt
Term
50
Device: Flexi-Bar
Epicondylitis; Pain;
vibration device only; Tendinopathy
Device: Flexi-Bar +
XCO-Trainer
Device: ExploR®
Degenerative
Modular Radial Head Conditions of the
Radial Head/Neck;
Post-traumatic
Conditions of the
Radial Head/Neck
139
Jan-11 Sep-11 Hannover
Medical School
Child Dec-09 Jun-10 Biomet
Adt
Orthopedics,
Sen
LLC
The effect of dexmedetomidine in
addition to local anaesthetic on the
block of nerves in the arm
RCT
ISRCTN67622282
Levobupivacaine + Forearm and hand
dexmedetomidine + surgery patients
isotonic sodium
chloride;
Levobupivacaine +
isotonic sodium
chloride
Drug: Xylocaine
Forearm and Arm
Surgery
Comparison Between Two
Different Volumes of Anesthesia
Drug in Forearm Surgery
NCT01216488
TENDOSHOCK-2010 Combination Drug: Polidocanol; Tendinopathy;
Therapy for Athletic
Device: Focused
Epicondylitis;
Tendinopathies
extracorporeal shock Achilles, Patella,
wave therapy; Drug: Elbow
Topical NO;
study
Behavioral: Painful
NCT01185951
eccentric training in
Achilles
tendinopathy;
Behavioral: Painful
eccentric training for
patella tendinopathy
on 25° decline board;
Behavioral: Painful
elbow tendinopathy
using Thera-Band
Flex-Bar
ED95 bupivacaine and
Bupivacaine for
Routine hand,
supraclavicular block
supraclavicular
forearm or upper
brachial plexus block limb surgery
ISRCTN63230740
Botulinum Toxin as a Novel
Drug: Botulinum
Post Traumatic
Treatment for Prevention of Post- Toxin Type A; Drug: Stiffness
Traumatic Elbow Stiffness
Saline
NCT01129583
Comp
64
Adt Nov-11 Feb-12 Cumhuriyet
Sen
University
(Turkey)
Comp
72
Adt Jan-10 Jun-11 University
Sen
Hospital, Brest
Active,
NR
114
Adt Jan-07 Dec-10 Hannover
Sen
Medical School
Comp
40
Sen
Leeds (UK)
Comp
18
Adt Nov-03 May-10 Columbia
Sen
University;
Allergan
140
Ultrasound-guided Axillary Plexus
Block - Dose Reduction of
Prilocaine
Phase IV: Non-randomized,
NCT01309360
Procedure
Human Upper Extremity
Allotransplantation
study
NCT01459107
Preservation of Joint Function
Using Postoperative Continuous
Passive Motion (CPM) A Pilot
Study
NCT01420887
Uncemented Total Elbow
Arthroplasty Data Collection
Prospective study
NCT00974298
Early Discharge in Patients
Undergoing Elbow Arthroscopy
RCT
NCT01151241
Prevention of Phantom Limb and
Blocks
study
NCT00771862
Drug: midazolam;
Drug: prilocaine 1%;
Drug: prilocaine 1%;
Drug: prilocaine 1%
Other Surgical
Comp
Procedures; elective
surgery on the distal
forearm or the hand
incl. for carpal tunnel
sydrome
Procedure:
Amputation,
Deceased donor
Traumatic; Wounds
hand transplantation; and Injuries; Hand
Drug: Bone marrow Injuries
cell-based therapy &
single-drug
immunosuppression.
Procedure:
Elbow Injury
Continuous Passive
Motion; Procedure:
Physical Therapy
Procedure: Total
elbow replacement
arthroplasty
Total Elbow
Arthroplasty
120
Adt Sep-09 Apr-10 Helios Research http://ClinicalTrials.gov/show/NCT01309360
Sen
Center
Rec
30
Adt
Sen
Not yet
Rec
50
Child Aug-11 Jul-14 Mayo Clinic
Adt
Sen
Rec
100
Adt Mar-09 Mar-14 Vanderbilt
Sen
University
40
Adt
18
Sen
California, San
Diego; National
Institute of
General Medical
Sciences
(NIGMS)
Procedure: Elbow
Elbow Arthroscopy
Rec
arthroscopy with
Surgery
infraclavicular nerve
block and continuous
local anesthetic
infusion to day 3 post
op.; Other: Early
Discharge; Other:
Normal Discharge
Procedure:
Amputation;
Active,
NR
Stump Pain
141
Jul-11 Jun-21 Johns Hopkins
University
Jul-10 Apr-13 University Health http://ClinicalTrials.gov/show/NCT01151241
Network,
Toronto
perineural
ropivacaine
and Stump Pain
RCT, efficacy study
NCT00667264
Amputation;
Phantom Limb;
Stump Pain
Comp
7
Evaluation the Operative
Procedure: tear of
Procedure Among Patients That the distal tendon in
Suffer From Tear of the Distal
the biceps muscle
Tendon of the Biceps
Retrospective, case-crossover
study
NCT01343875
Prospective Biceps Study
Procedure: Distal
Biceps Re-Insertion
NCT01317719
Surgery
Perineural Catheter Insertion
Procedure: Sciatic
Distance for Continuous Peripheral catheter left 0-1cm
Nerve Blocks
past needle tip vs. 5Phase IV: RCT, safety/efficacy 6cm past needle tip
study
NCT00997867
Elaboration of a Pre-surgery
Procedure: fMRI;
Mapping Protocol of Primary Motor Procedure: mTMS
Cortex, Prior to an Implementation
of a Stimulation of Primary Motor
Cortex for Patients With
Deafferentiation of Brachial Plexus
Pain
assignment
NCT01104506
Trial Comparing Single Versus
Procedure: Distal
Double Incision to Repair Distal
bicep tendon
Bicep Tendon Ruptures
reconstruction
RCT
NCT01322828
Biceps Tendon
Rupture
Not yet N/K
Rec
Sen
California, San
Diego; Summit
Medical;
National Institute
of General
Medical
Sciences
(NIGMS)
Adt
N/K Dec-11 Hadassah
Medical
Organization
Jan-11 West Penn
Allegheny Health
System
Adt Nov-09 Oct-10 University of
Sen
California, San
Diego
Biceps Tendon
Rupture
Invite
N/K
Lower Extremity
Surgery; Upper
Extremity Surgery;
Post-operative Pain
Comp
350
Painful Avulsion of
Brachial Plexus
Term
13
Adt Apr-10 Sep-10 Nantes
Sen
University
Hospital
Distal Bicep Tendon
Rupture
Comp
92
Adt Mar-04 Jan-10 Hand and Upper http://ClinicalTrials.gov/show/NCT01322828
Sen
Limb Clinic,
Canada
142
Adt
Sen
N/K
Optimization of Catheter Insertion
Site for Continuous Peripheral
Nerve Blocks
study
NCT00876746
Procedure:
Supraclavicular vs.
Infraclavicular
ropivicaine infusion
Other
Interface Kinematics of
Other: Socket
Transhumeral Prosthetic Sockets
Using XROMM
study
NCT01546675
Upper-extremity
Surgery; Postoperative Pain
Traumatic
Amputation of Arm
Comp
60
Sen
California, San
Diego
Rec
2
Adt Jan-12 Mar-13 Providence VA http://ClinicalTrials.gov/show/NCT01546675
Sen
Medical Center;
Department of
Veterans Affairs
Recruit
n
Age Start
(Grp) Date
79
Child Jan-09 May-10 Orthopedic
Hospital Vienna
Speising
A8. HIP
A8A: PAEDIATRICS
Title
Interventions
CT ID
Predictive Factors for the
Development of Osteonecrosis
After the Treatment of the
Developmental Dislocated Hip
NCT01133938
Conditions
Predictors of
Comp
Osteonecrosis of the
Femoral Head After
Treatment of the
Dislocated Hip
143
End Sponsors
Date
URL
Title
CT ID
Behavioural
Enhanced Rehabilitation for
Elderly People With a Hip Fracture
and Depression
NCT00951691
Efficacy of a Post-Rehabilitation
Exercise Intervention
RCT
NCT00592813
Interventions
Conditions
Recruit
n
Behavioral:
Enhanced acute
medical
rehabilitation;
Behavioral:
Treatment as usual
Behavioral:
Enhanced Strong for
Life; Behavioral:
cardiovascular
nutrition education
Hip Fracture;
Depression
Rec
40
Adt Aug-09 Dec-12 National Institute http://ClinicalTrials.gov/show/NCT00951691
Sen
of Mental Health
(NIMH)
Hip Fracture;
Disability
Rec
230
Invite
30
Adt Apr-08 Jul-12 Boston
Sen
University;
National Institute
of Nursing
Research;
Spaulding
Rehabilitation
Hospital
Child Nov-10 May-12 Meir Medical
Adt
Center
Sen
The Relationship Between Pet
Behavioral: care of
Therapy and “Well-being” in
guinea pigs;
Geriatric Rehabilitation In-patients" Behavioral: guinea
pigs
NCT01234844
Cerebrovascular
Accident; Hip
Fracture
Device
AMIStem Primary Hip System
Device: AMIStem Hip Osteoarthritis;
Prospective Post-marketing Multi- System
Arthritis; Avascular
centre Surveillance Study
Necrosis; Fracture of
the Femoral Neck or
Head; Congenital
NCT01107340
Hip Dysplasia
Rec
Age Start
(Grp) Date
End Sponsors
Date
URL
500 Child Feb-10 Feb-24 Medacta
Adt
International SA
Sen
144
A Multi-centre Study to Assess the Device: DePuy ASR
Long-term Performance of the
Hip System
DePuy ASR™ System in Primary
Hip Resurfacing Surgery
study
NCT00208377
Rheumatoid Arthritis; Term
Osteoarthritis; Posttraumatic Arthritis;
Collagen Disorders;
Avascular Necrosis;
Nonunion of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis.
Post-Market Study of the Modular Device: Modular
Asceptic Loosening;
Rec
Revision Hip System
Revision Hip System Osteolysis;
Traumatic Fracture;
NCT01464645
Failed Total Hip
Implant
Using Alternative Implants for the Device: Open
Femoral Neck
Rec
Surgical Treatment of Hip
reduction internal
Fractures
Fractures (The FAITH Study)
fixation (ORIF) with
single sliding hip
NCT00761813
screw; Device: ORIF
with multiple
cancellous screws
Post-Operative Delirium in Elderly
Surgical Patients
RCT, efficacy study
NCT00590707
Device: Maintenance Hip Fractures;
of level of awareness Delirium
by use of a BIS
monitor & the OASS;
Device: Maintenance
of level of awareness
by use of a BIS
monitor and the
OASS.
Rec
228
Adt
Jul-03
Jul-20 DePuy
International
200
Adt Jan-12 Dec-17 Encore Medical, http://ClinicalTrials.gov/show/NCT01464645
Sen
L.P.; DJO
Incorporated
1500 Adt Mar-09 Mar-16 National Institute http://ClinicalTrials.gov/show/NCT00761813
Sen
of Arthritis and
Musculoskeletal
and Skin
Diseases;
Canadian
Institutes of
Health
Research;
Stichting Nuts
Ohra (SNO);
Physicians
Services
Incorporated
(PSI) Foundation
210 Adt Jan-05 Dec-15 Johns Hopkins http://ClinicalTrials.gov/show/NCT00590707
Sen
University;
National
Institutes of
Health
145
Proximal Femoral Nail Antirotation
(PFNA) Versus PFNA
Augmentation
NCT01473082
Proximal Femur Locking
Compression Plates Versus
Trochanteric Nails
parallel assignment
NCT01128868
Treatment of Intertrochanteric
Fracture With New Type of
Intramedullary Nail
study
NCT01437176
Treatment of Acetabular Posterior
Wall Fracture With Anatomical
Locking Plate
study
NCT01437150
Cemented vs Non-cemented
Semiendoprosthesis in the
Treatment of Proximal Femoral
Fractures
NCT00859378
Device: PFNA
Augmentation
(Synthes); Device:
PFNA (Synthes)
Hip Fractures;
Closed Fracture of
Hip
Rec
144
Sen Feb-12 Dec-15 AO Clinical
Investigation and
Documentation
Reverse Oblique
Intertrochanteric
Fractures; Reverse
Oblique
Subtrochanteric
Fractures
Device: new type of Intertrochanteric
intramedullary nail; Fracture
Device: The
intramedullary nail of
PFNA
Rec
112
Adt May-11 Sep-13 AO Clinical
Sen
Investigation and
Documentation
Rec
36
Adt Sep-11 Aug-13 Peifu Tang
Sen
Device: Anatomical Fracture of
locking plate;
Acetabulum
Procedure: The
Reconstructive Plate
Rec
36
Adt Aug-11 Jul-13 Peifu Tang
Sen
Device: Cemented Hip Fracture;
semiendoprosthesis; Proximal Femoral
Device: nonFracture
cemented
Rec
400 Child Oct-08 Dec-12 Kuopio
Adt
University
Sen
Hospital; The
Finnish
Foundation of
Orthopedics and
Traumatology
200 Adt Feb-07 Dec-12 McGill University http://ClinicalTrials.gov/show/NCT00597779
Sen
Health Center;
Orthopaedic
Trauma
Association
40
Adt May-07 Dec-12 Chinese
Sen
University of
Hong Kong
Fonly
Randomized Comparison of 2
Fixation Techniques for Unstable
Intertrochanteric Hip Fractures
NCT00597779
Study of Low-Magnitude, HighFrequency Vibration Treatment on
Osteoporotic Hip Fracture Healing
study
NCT01293721
Device: Dynamic Hip Hip Fractures
Screw (DHS);
Trochanteric Fixation
Nail (TFN)
Device: Proximal
femur locking plate;
Device:
Intertrochanteric nail
Device: Lowmagnitude high frequency vibration
treatment
Hip Fracture
Active,
NR
Rec
146
InterTAN IM Nail Versus Sliding
Hip Screw in Geriatric Fractures
RCT
NCT00664950
Device: sliding hip
screw; Device:
IntertAn IM nail
Hip Fractures
Comparing Weight Bearing After
Intramedullary Fixation Devices for
the Proximal Femur Fracture
NCT01509859
Device: PFNA
proximal femur nail
device (Synthes);
Device: INTERTAN
proximal femur nail
device
(Smith&Nephew)
Hip Protector for Prevention of Hip
Fracture
study
NCT01017341
Neck of femur Optimisation
Therapy-Targeted Stroke volume
RCT
ISRCTN88284896
Comparison of Gamma Nail
Versus Dynamic Hip Screw for the
Treatment of Unstable
Intertrochanteric Fractures
RCT, efficacy study
NCT01173744
Role of Vacuum Assisted Closure
(VAC) Device in Postoperative
Management of Pelvic and
Acetabular Fractures
RCT, efficacy study
NCT00635479
Device: PSU hip
protector
Closed Comminuted Rec
100
Oblique
Intertrochanteric
Fracture of Neck of
Right Femur; Closed
Comminuted
Oblique
Intertrochanteric
Fracture of Neck of
Left Femur
Hip Fracture
Not yet 200
Rec
LiDCO machine
Device: Gamma-3
Nail; Device: DHS
Surgical repair of
fracture to neck of
femur under spinal
anaesthesia
Intertrochanteric
Femoral Fractures
Device: Wound Vac; Pelvic Bone
Other: Gauze
Fractures;
dressing
Acetabular Fracture;
Hip Fractures
Rec
240
Active
130
Rec
60
Rec
200
147
Adt Nov-07 Nov-12 Lawson Health
Sen
Research
Institute;
Orthopaedic
Research
Foundation
Adt Dec-11 Sep-12 Rabin Medical
Sen
Center
Adt Jun-10 Sep-12 Prince of
Sen
Songkla
University
Adt Jan-09 Aug-12 Nottingham
University
Hospitals NHS
Trust (UK)
Adt Jul-10 Jul-12 Wolfson Medical http://ClinicalTrials.gov/show/NCT01173744
Sen
Center
Adt Mar-08 Jun-12 University of
Sen
MissouriColumbia;
University of
California, Davis;
University of
Alabama at
Birmingham;
Medical College
of Wisconsin
Treatment of Unstable
Trochanteric Fractures With the
Proximal Femoral Nail Antirotation (PFNA)-Asia
NCT00873548
Comparison Study of 3-4-screwsinternal Fixation With Multi-screwsystem Targon FN for Femoral
Neck Fracture
NCT00829725
Intracapsular Femoral Neck
Fractures Fixation With a Dynamic
Locking Plate and Screw System,
Targon FN
NCT00830687
Comparison Between Gamma 3
Nail and ACE Trochanteric Nail
efficacy study
NCT00367406
Comparison of the Results of
Treatment by Gamma Nail Versus
Dynamic Hip Screw for Unstable
Intertrochanteric Hip Fractures
RCT
NCT01238068
Influence of Bone Strength
Measured by DensiProbe on Bone
Related Fixation Failure
NCT00822159
Device: PFNA-Asia
Trochanteric
Fractures
Active,
NR
298
Adt Nov-07 Mar-12 AO Clinical
Sen
Investigation and
Documentation;
Synthes Inc.
Device: screwsFemoral Neck
internal fixation;
Fractures
Device: TARGON FN
Rec
300
Adt Jan-09 Jan-12 Sheba Medical
Sen
Center
Device: TARGON FN Femoral Neck
Fractures
Rec
100
Adt Jan-09 Jan-12 Sheba Medical
Sen
Center
Device: Gamma 3
nail versus ACE
trochanteric nail
Rec
100
Adt Nov-06 Dec-11 University
Sen
Hospital, Ghent
Device: gamma nail Intertrochanteric
stryker
Fractures of the Hip
Not yet
Rec
60
Adt Nov-10 Nov-11 Tel-Aviv
Sen
Sourasky
Medical Center
Device: DensiProbe Femoral Fractures;
Hip
Hip Fractures;
Osteoporosis; Bone
Density
Term
198
Sen
Investigation and
Documentation
Pertrochanteric and
Subtrochanteric
Femur Fractures
148
A Single Centre Study to Assess Device: DePuy
the Long-term Performance of the ASR™ Hip System
DePuy ASR™ System in Primary
Hip Resurfacing Surgery
study
NCT00872794
Evaluation of the Proximal Femoral Device: Proximal
Nail Antirotation With Cement
Femoral Nail
Augmentation in Osteoporotic
Antirotation(PFNA)
Femoral Neck Fractures
with cement
augmentation
assignment
NCT01235169
Comparison of Treatment
Device: 2 Versus 4
Outcomes in Hip Fractures
Hole DHS
Surgically Fixed With Either a Two
or Four Hole Device.
study
NCT00323232
Retrospective Study of the
Device: Encore
Linear™ Hip
Linear™ Hip System
Phase IV: Retrospective, cohort
study
NCT00764959
Proximal Femoral Nail
Antirotation™ (PFNA) Versus
Gamma Nail 3™ (Gamma3) for
Intramedullary Nailing of Unstable
Trochanteric Fractures
NCT00736684
Device: Proximal
Femoral Nail
Antirotation™
(PFNA); Device:
Gamma Nail 3™
(Gamma3)
Adt Nov-03 Sep-11 DePuy
International
Aug-11 Hadassah
Medical
Organization
Collagen Disorders;
Avascular Necrosis;
Nonunion of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis.
Proximal Femur
Not yet
Fracture
Rec
50
Hip Fracture
Comp
400
Adt Dec-10 Apr-11 University of
Sen
British Columbia
Osteoarthritis;
Term
Femoral Fracture;
Correction of a
Functional
Deformity; Avascular
Necrosis
Unstable
Comp
Trochanteric
Fractures
200
Adt Oct-07 Feb-11 Encore Medical, http://ClinicalTrials.gov/show/NCT00764959
Sen
L.P.
440
Sen
Investigation and
Documentation;
Synthes Inc.
Adt
Sen
149
Clinical Evaluation on HA Coated
Dynamic Hip Screws for
Trochanteric Femoral Fractures
NCT00756431
Device: Hip Fracture Osteoarthritis
reduction Screw
without HA Coating
(Hiploc); Device: Hip
Fracture reduction
Screw with HA
Coating (Hiploc)
Fixation using Alternative Implants Sliding hip screws; Femoral neck
for the Treatment of Hip fractures Cancellous screws fractures
(FAITH): a multi-centre
randomised trial comparing sliding
hip screws and cancellous screws
on revision surgery rates and
quality of life in the treatment of
femoral neck fractures
RCT
ISRCTN25524122
Dietary supplements
Hip Fracture Surgery and Oral
Dietary Supplement: Hip Fracture
Nutritional Supplements
Oral nutritional
Supplement; Dietary
study
Supplement: Placebo
NCT01505985
Hyperprotein Nutritional
Dietary Supplement: Sarcopenia; Hip
Intervention in Elderly Patients
Ensure Plus
Fracture
With Hip Fracture and Sarcopenia Advance
RCT, efficacy study
NCT01404195
Nutritional Intervention for Geriatric Dietary Supplement: Hip Fractures
Hip Fracture Patients
Protein
RCT, efficacy study
supplementation
NCT01088139
Nutritional Intervention in Hip
Dietary Supplement: Hip Fracture;
Fracture Patients
Cubitan
Malnutrition
RCT, efficacy study
NCT00523575
Wdrwn
0
Child Jan-04 Jun-10 Biomet, Inc.;
Adt
Hvidovre
Sen
University
Hospital; Biomet
U.K. Ltd.
Comp
80
Adt Jun-08 Jan-10 McMaster
Sen
University
(Canada)
Rec
192
Sen Jan-12 Jul-14 Nestlé Nutrition http://ClinicalTrials.gov/show/NCT01505985
Corporate
Rec
100
Adt Jan-12 Mar-13 Hospital San
Sen
Juan de Dios,
Spain
Comp
126
Adt Nov-08 Apr-11 Kowloon
Sen
Hospital, Hong
Kong
Comp
210
Adt Aug-07 Jun-10 Maastricht
Sen
University
Medical Center;
ZonMw: The
Netherlands
Organisation for
Health Research
and
Development
150
Effect of Teriparatide on Hip
Fracture Healing
NCT01473589
Second Study of the Effect of
Teriparatide on Hip Fracture
Healing
NCT01473602
A Study That Will Compare the
Effect of Two Drugs on Patients
With Low Bone Mass and a
Recent Hip Fracture
NCT00887354
Statin in Hip Fracture
study
NCT01494090
Postoperative Blood Transfusion
for Frail Elderly With Hip Fracture
NCT01102010
Study To Assess Fracture Healing
With Sclerostin Antibody
study
NCT01081678
Study of the Effect of Tranexamic
Acid Administered to Patients With
Hip Fractures. Can Blood Loss be
Reduced?
NCT01535781
Parathyroid hormone in the
recovery from hip fractures: a pilot
study
RCT, pilot study
ISRCTN03362357
Drug: Teriparatide;
Drug: Placebo
Femur Neck
Fracture
Rec
1220 Adt Feb-12 Oct-15 Eli Lilly and
Sen
Company
Drug: Teriparatide;
Drug: Placebo
Femur Neck
Fracture
Rec
1220 Adt Jan-12 Oct-15 Eli Lilly and
Sen
Company
Drug: Teriparatide;
Drug: Risedronate;
Drug: Placebo,
weekly; Drug:
Placebo, daily
Osteoporosis
Rec
242
Drug: Rosuvastatin; Hip Fracture
Drug: Placebo
Rec
Biological: Blood
transfusion
Rec
1222 Adt Aug-11 Mar-14 University
Sen
Hospital, Brest;
Ministry of
Health, France
284 Adt Jan-10 Dec-13 University of
Sen
Aarhus
Hip Fracture
Drug: Placebo; Drug: Fracture Healing;
AMG 785 140 mg; Hip
Drug: AMG785
70mg; Drug: AMG
785 210mg
Drug: Tranexamic
Hip Fracture;
Acid; Drug: Placebo Anemia
Tereparatide
Hip fracture
(Forsteo®) 20 µg/day
injections; Standard
care
Adt Apr-09 Jul-14 Eli Lilly and
Sen
Company
Rec
330
Adt Jun-10 Dec-13 Amgen
Sen
Rec
120
Adt Sep-11 Sep-13 Hvidovre
Sen
University
Hospital
Active
40
Adt Jan-11 May-13 North Bristol
NHS Trust (UK) trials.com/ISRCTN03362357
151
Preoperative Levosimendan and
Heart Failure
study
NCT01022983
Norspan Versus Oxycontin as
Postoperative Painkiller to
Proximal Extracapsular Fractures
of the Femur
NCT00964808
Efficacy and Safety of Intravenous
Iron Sucrose in Patients With Hip
Fracture to Prevent Perioperative
Anemia
study
NCT01084122
Intravenous Acetaminophen as
Adjuvant Therapy for Pain Control
in Geriatric Hip Fracture Patients
NCT01520298
Effectiveness of Two Types of
Treatment in Restoring Muscle
After Hip or Knee Surgery
NCT00393848
Drug: Levosimendan; Heart Failure; Hip
Drug: Placebo
Fracture
Rec
70
Drug:
Buprenorphine;
Drug: Oxycodone
Pain, Postoperative
Rec
50
Drug: Iron sucrose
Hip Fracture;
Not yet 360
Surgical Intervention Rec
Drug: Essential
amino acid
supplement; Drug:
Ketoconazole; Drug:
Whey protein
Intrathecal Morphine,Femoral
Nerve Block,Periarticular
Bupivacaine Infiltration for Pain
After Intramedullary Hip Screw
NCT01219088
Hip Fracture Surgery in Elderly
Patients
NCT01199276
Drug: Placebo; Drug: Pain; Hip Fracture
Acetaminophen IV
Adt Apr-11 Feb-13 Sykehuset i
Sen
Vestfold HF;
Orion
Corporation,
Orion Pharma
Adt Sep-09 Jan-13 Vejle Hospital; http://ClinicalTrials.gov/show/NCT00964808
Sen
Norpharma A/S
Adt May-10 Dec-12 Hospital Clinic of http://ClinicalTrials.gov/show/NCT01084122
Sen
Barcelona
Rec
46
Adt Dec-11 Dec-12 Lancaster
Sen
General Hospital
Hip Fracture;
Osteoarthritis;
Femur Head
Necrosis
Active,
NR
120
Drug: Bupivacaine,
morphine
Femoral Neck
Fractures
Rec
80
Sen
Arkansas;
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Adt Sep-10 Sep-12 Mahidol
Sen
University
Drug: Xenon; Drug:
Sevoflurane
Delirium
Rec
256
152
Sen Sep-10 Sep-12 Air Liquide
Santé
International; i3
Innovus
Hemostasis in Kocher-Langenbeck Biological: Vitagel
Fracture Fixation;
Approaches for Acetabular
topical surgical
Intra-Articular
Surgery Using a Topical Surgical hemostat
Fractures;
Hemostat (Vitagel)
Acetabulum
NCT01230931
Impact of Pre-surgical Nasal
Drug: 3M Skin and Surgical Site
Infection; displaced
Bacterial Reduction on
Nasal Antiseptic
hip fractures; spinal
Postoperative Surgical Site
instability/fractures
Infections
assignment
NCT01148030
Single Dose of Dexamethasone in Drug:
Fractured Neck of
Femur Fractures
Dexamethasone
Femur
acetate; Drug:
NCT01550146
Placebo
TRAUMEEL for Pain After Fracture Drug: Traumeel S; Pain; Fracture of
of Neck of Femur
Drug: Placebo
Neck of Femur
remedy
NCT00307905
A Non-inferiority Study Comparing Biological: Heparin Hip Fracture Surgery
Two Heparin Sodium Preparations Sodium - Eurofarma;
in Hip Fracture Surgery
Biological: Heparin
Sodium - APP
study
Pharmaceuticals
NCT01352039
Ropivacaine Hypobaric Spinal
Drug: 6 mg of
Femoral Neck
Anaesthesia in Traumatic Hip
ropivacaine; Drug: 8 Fracture
Surgery
mg of ropivacaine;
Phase IV: RCT, safety/efficacy Drug: 10 mg of
study
ropivacaine; Drug: 12
NCT01005550
mg of ropivacaine
Comparing Different Routes and Drug: Phytonadione; Bleeding;
Doses of Phytonadione (Vitamin K) Drug: Phytonadione Complications
for Reversing Warfarin Treated
Patients With Hip Fracture Before
Surgery
RCT, efficacy study
NCT00905229
Rec
50
Rec
400 Child Jun-10 Jul-12 3M
Adt
Sen
Rec
40
Wdrwn 224
Adt
Adt
Sen
Oct-10 Jul-12 The University of http://ClinicalTrials.gov/show/NCT01230931
Texas Health
Science Center,
Houston
Jul-09
Jul-12 Cork University http://ClinicalTrials.gov/show/NCT01550146
Hospital;
University of
Bristol
Adt Jan-11 Jun-12 Shaare Zedek
Sen
Medical Center
Not yet 544
Rec
Adt Oct-11 Mar-12 Eurofarma
Sen
Laboratorios
S.A.
Comp
64
Sen Apr-09 Mar-12 Hospices Civils
de Lyon
Not yet
Rec
60
Adt May-09 Mar-12 HaEmek Medical http://ClinicalTrials.gov/show/NCT00905229
Sen
Center, Israel
153
Efficacy of Ferric Carboxymaltose
With or Without Erythropoietin
Versus Placebo in Reducing Redcell Transfusion Packs in Hip
Fracture Perioperative Period
NCT01154491
A Dose Finding Study for Pain
Relief of a Broken Hip
single group assignement,
NCT00926666
Postoperative Analgesia With
Local Infiltration After Hip Fracture
Of Intertrochanteric Type
NCT01119209
Femoral nerve blockade in hip
fracture patients
RCT
ISRCTN46653818
Does Omeprazole Decrease
Intestinal Calcium Absorption?
assignment
NCT00582972
Drug: Ferric
Hip Fractures
carboxymaltose;
Drug: Ferric
carboxymaltose and
Erythropoetin; Drug:
Placebo
Perioperative Analgesia by
Femoral Perineural Catheter for
Femoral Neck Fracture - Study
KTcol
NCT01052974
Feasibility And Safety Study Of
rhBMP-2/CPM For Hip Fractures
Phase II: RCT, safety study
NCT00384358
Drug: ropivacaine
Rec
306
Adt Jun-10 Jun-11 Fundación
Sen
Pública
Andaluza para la
gestión de la
Investigación en
Sevilla
Adt Oct-09 Apr-11 NHS Greater
Sen
Glasgow and
Clyde; Chief
Scientist Office
of the Scottish
Government
Child Feb-08 Jan-11 Odense
Adt
University
Sen
Hospital
Drug:
Levobupivacaine
Femoral Neck
Fractures
Not yet
Rec
48
Drug: Ropivacaine;
Drug: Saline
Hip Fracture of
Intertrochanteric
Type
Comp
74
Femoral nerve
blockade; Regular
use of opioids
Hip fracture
Comp
250
Sen Mar-09 Dec-10 Umeå University http://www.controlled(Sweden)
Drug: Omeprazole
Osteoporosis;
Comp
Achlorhydria; GERD;
Hip Fracture
21
Child Jan-08 Dec-10 University of
Adt
Wisconsin,
Sen
Madison
Femoral Neck
Fracture
Drug: rhBMP-2/CPM; Fractures
Drug: rhBMP-2/CPM;
Other: surgical
intervention alone
Rec
60
Comp
108
154
Fonly
Adt Mar-09 Sep-10 University
Sen
Hospital, Angers
Adt Dec-06 Jun-10 Wyeth is now a
Sen
wholly owned
subsidiary of
Pfizer
Prevention of Venous
Drug: YM150
Thromboembolism in Subjects
Undergoing Hip Fracture Surgery
or Surgery in the Lower
Extremities
single group assignement,
NCT00937911
Comparison of the post-operative Fascia iliaca
pain relief provided by the
compartment block 1
administration of either a femoral mg/kg OR 1.5 mg/kg
nerve block or fascia iliaca
levobupivacaine;
compartment block at one of two Femoral nerve block
different doses in patients
1 mg/kg OR 1.5
undergoing surgery for hip fracture mg/kg
RCT
levobupivacaine
ISRCTN51569968
Study of DU-176b, Prevention of Drug: DU-176b
Venous Thromboembolism in
(edoxaban); Drug:
Patients After Hip Fracture Surgery Enoxaparin sodium
20mg
study
NCT01181141
Evaluation of AVE5026 as
Drug: Semuloparin
Compared to Placebo for the
sodium (AVE5026);
Extended Prophylaxis of Venous Drug: Placebo
Thromboembolism in Patients
Having Undergone Hip Fracture
Surgery
NCT00709904
Procedure
Intramedullary Nail Versus Sliding
Hip Screw Inter-Trochanteric
Evaluation
RCT
NCT01380444
A Comparison of Two Pain Control
Techniques on Deliruim in Hip
Fracture Patients
RCT, efficacy study
NCT01547468
Procedure: Gamma3
Intramedullary Nails
(Stryker); Procedure:
Sliding Hip Screws
Venous
Thromboembolism
Comp
101
Adt Jun-09 Apr-10 Astellas Pharma http://ClinicalTrials.gov/show/NCT00937911
Sen
Inc
Fractured neck of
femur
Term
120
Adt Aug-09 Feb-10 Belfast Health
and Social Care trials.com/ISRCTN51569968
Trust (UK)
Venous
Thromboembolism
Comp
92
Adt Oct-08 Feb-10 Daiichi Sankyo http://ClinicalTrials.gov/show/NCT01181141
Sen
Inc.; Daiichi
Sankyo, Tokyo,
LTD.
Venous
Thromboembolism
Comp
469
Adt Jun-08 Jan-10 Sanofi-Aventis
Sen
Rec
736
Rec
270
Adt Dec-11 Dec-15 Stryker Trauma http://ClinicalTrials.gov/show/NCT01380444
Sen
GmbH; Stryker
Osteosynthesis;
Global Research
Solutions
Adt Mar-12 Mar-15 Leslie Thomas; http://ClinicalTrials.gov/show/NCT01547468
Sen
American
Society of
Anesthesiologist
s
Femoral Neck
Fractures;
Intertrochanteric
Fracture
Procedure: Femoral Hip Fracture
Nerve
Catheterization;
Procedure:
Intravenous Opioids
155
Eva-Hip, Evaluation of
Rehabilitation After Hip-fracture
Phase I/II: RCT
NCT01379456
Procedure:
physiotherapy
Hip Fracture
Rec
100
Rec
108
Rec
200
Hip Fracture; Aged
Active,
NR
400
Left Ventricular
Dysfunction;
Femoral Fracture
Not yet 200
Rec
On the Impact of Bleeding on Two Procedure: MISS;
Surgical Treatment
Strategies Osteosynthesis of
Procedure: PHS
Trochanteric Fractures
Phase IV: RCT
NCT01427036
Improving Pain and Function in Hip Procedure: Femoral Pain; Hip Fractures
Fracture
Nerve Block
NCT00749489
A New Clinical Pathway for
Procedure: geriatric
Patients With Fractured Neck of
work-up; Procedure:
Femur
Orthopedic
study
NCT00667914
Optimization Study of Cardiac Risk Procedure: Colloids,
Patients With Hip Fracture
dobutamin,
RCT, efficacy study
levosimendan
NCT01219712
Prospective Trial on Trochanteric
Femur Fractures Treated With or
Without a Trochanter Support
Plate
RCT, efficacy study
NCT00626470
Procedure: Addition Femoral Fractures
of TSP to DHS
Rec
100
156
Sen Feb-11 Dec-14 Norwegian
University of
Science and
Technology;
Trondheim
kommune, enhet
for fysioterapi;
Norsk kvinners
sanitetsforening
Sen
Hospital, Tours
Adt Nov-08 Dec-13 Mount Sinai
Sen
School of
Medicine;
National Institute
on Aging (NIA)
Sen Apr-08 Apr-13 Norwegian
University of
Science and
Technology
Adt Jan-11 Feb-13 University
Sen
Hospital,
Linkoeping;
University
Hospital Orebro;
Ryhov County
Hospital
Adt Dec-08 Dec-12 St. Olavs
Sen
Hospital
Blood Loss and Complications of
Internal Fixation of Femoral Neck
Fractures in Patients Treated With
Clopidogrel
study
NCT00749710
Identification of the
Microcirculation of the Caput
Femoris After Fracture of the
Femoral Neck
NCT01483404
Randomised trial of a blood
transfusion policy after fracture of
the proximal femur (hip fracture)
RCT
ISRCTN61328173
Optimal Positioning of Local
Anaesthetic in Femoral Nerve
Block Prior to Hip Surgery
NCT01527812
Haemodynamic protocols in
traumatology
RCT
ISRCTN66123742
The Effect of Loss of Offset After
Pertrochanteric Fracture Treated
With a Intramedullary Nail
NCT01344785
The Warwick Hip Trauma Study
RCT
ISRCTN49197425
Procedure:
clopidogrel;
Procedure: no
antiaggregant
therapy
Femoral Neck
Fractures;
Pertrochanteric
Fractures;
Antiaggregant
Therapy
Not yet 100
Rec
Adt Sep-08 Dec-12 Tel-Aviv
Sen
Sourasky
Medical Center
Procedure:
Measurement with
O2c
Microcirculation of
the Caput Femoris
Not yet
Rec
30
Adt Jun-12 Nov-12 RWTH Aachen
Sen
University
Oral iron
Fracture of the
supplements; Blood proximal femur (hip
transfusion
fracture)
Active
N/K
Adt Aug-02 May-12 Department of
Sen
Health (UK)
Procedure: Femoral Fractured Neck of
nerve block
Femur
Comp
60
Adt Feb-10 Feb-12 Cork University http://ClinicalTrials.gov/show/NCT01527812
Sen
Hospital
Targeted-volume
Hemiarthroplasty of
application guided by femoral neck
oesophageal
fractures
Doppler; Postoperative directives
versus conventional
volume application
Procedure:
Intertrochanteric
Intramedullary nailing Fractures
Comp
40
Adt Jun-08 Dec-11 Charité http://www.controlledSen
University
Medicine Berlin,
Germany
Rec
100
Adt Apr-10 Nov-11 Danderyd
Sen
Hospital
Fixed-angle screw
Intracapsular
and plate fixation;
fractures of the
Standard of care
proximal femur
fixation + placebo
injection; Standard of
care fixation + PRP
injection
Comp
225
Sen Aug-09 Aug-11 University of
Warwick (UK)
157
Stroke Volume Optimisation in
Patients With Hip Fracture
NCT00444262
Procedure:
hemodynamic
optimisation guided
using esophageal
Doppler; Drug:
VOLUVEN and
others solute
Procedure: Intertan
Term
215
Sen Apr-07 Mar-11 Assistance
Paris; Fresenius
Kabi; GAMIDA
Trochanteric and
Comp
Subtrochanteric Hip
Fractures; Treatment
With a New Nail or a
Sliding Hip Screw
500
Adt Feb-08 Mar-10 Haukeland
Sen
University
Hospital
Hip Fracture
Comp
150
Adt Jun-08 Jan-10 AO Clinical
Sen
Investigation and
Documentation
Other: Strength
training
Hip Fracture
Rec
120
Adt Sep-10 Jun-13 Lolland
Sen
Community,
Denmark
Other: Multidisciplinary
management
program
Hip Fracture
Rec
160
Adt Sep-09 Dec-12 Chinese
Sen
University of
Hong Kong;
Queen Elizabeth
Hospital, Hong
Kong
Other: Urine color
Hip Fracture
Rec
200
Adt Jan-11 Dec-12 University
Sen
Hospital,
Linkoeping;
Vrinnevi Hospital
Not yet
Rec
60
Adt Feb-12 Aug-12 Meir Medical
Sen
Center; Clalit
Health Services
A Prospective Randomised
Multicenter Study Comparing the
Sliding Hip Screw and the Intertan
Nail in Trochanteric and
Subtrochanteric Femoral Fractures
RCT
NCT00621088
Accuracy of Navigation in
Procedure:
Placement of Sacroiliac Screw
Navigated;
Phase IV: RCT, safety/efficacy Procedure:
study
Conventional
NCT00955565
Other
Training of Patients With Hip
Fracture
NCT01174589
The Comparison of
Comprehensive Multi-disciplinary
Program and Conventional Care
Program on Fragility Fracture
Elderly
parallel assignement, efficacy
study
NCT01382875
Indicators of Operative and
Postoperative Complications in
Patients Operated for Hip Fracture
NCT01294930
Internal Fixation of Hip Fractures
Using Intraoperative Simultaneous
Two Axis View
NCT01524718
Hip Fractures
Radiation: Imaging Fracture Neck of
with two X-ray image Femur
intensifiers
158
HIP Fracture Accelerated Surgical Other: Accelerated Hip Fractures
TreaTment And Care tracK (HIP surgical hip fracture
ATTACK) Trial
repair
RCT
NCT01344343
Jul-11 May-12 Population
Health Research
Institute;
Hamilton Health
Sciences
Corporation
Strength Training After Hip
Other: training of
Hip Fracture
Not yet 60
Adt Jan-11 Jul-11 Hvidovre
Fracture Surgery
basic mobility; Other:
Rec
Sen
University
RCT
training of kneeHospital; IMK
NCT00848913
extension strength
Fonden; Danish
Physical
Therapy
Organization.
Retrospective Study: Hip Fractures Other: HBA1C
Type 2 Diabetes; Hip Comp 1162 Child Apr-11 Jun-11 Changi General http://ClinicalTrials.gov/show/NCT01379690
in Diabetic Patients
Fractures
Adt
Hospital
Sen
study
NCT01379690
Observation and Progressive
Other: Strength
Hip fracture
Active, 150 Adt Jun-07 Dec-10 Oslo University http://ClinicalTrials.gov/show/NCT01129219
Strength Training After Hip
training
NR
Sen
Hospital;
Fracture
Diakonhjemmet
RCT
Hospital
NCT01129219
Evaluation of home rehabilitation Multidisciplinary
Hip fracture
Comp 200 Sen Aug-08 Aug-10 Umeå University http://www.controlledfor hip fracture patients
home rehabilitation;
(Sweden)
RCT
Conventional
ISRCTN15738119
multidisciplinary
rehabilitation at
hospital
Effect of a Medical Food
Other: Medical Food Hip Fracture
Comp 127 Adt Nov-09 Sep-10 Abbott Nutrition http://ClinicalTrials.gov/show/NCT01011608
Supplement in Hospitalized
Supplement; Other:
Sen
Patients Recovering From Surgery standard hospital
food
NCT01011608
Troponin T Elevation in Patient
Undergoing Hip Fracture Surgery
NCT01352754
Hip Fracture
Rec
50
Adt
Sen
Rec
100
Adt Apr-11 Apr-14 Hadassah
Sen
Medical
Organization
159
Rivaroxaban Safety Profile in the
Prophylaxis of Venous
Thromboembolism After Hip
Fracture Surgery
NCT01509118
Improving Quality of Care for HipFracture Patients: Studies on Fasttrack Surgery
NCT01487772
Validation of Nexfin Cardiac
Output in Elderly Patients With Hip
Fracture
NCT01474824
Open Fracture of Hip
Rec
500
Adt
Sen
Jul-11 Sep-13 Phramonghttp://ClinicalTrials.gov/show/NCT01509118
kutklao College
of Medicine and
Hospital
(Thailand)
Hip Fractures
Rec
1300 Child Apr-10 Apr-13 Danderyd
Adt
Hospital
Sen
Hip Fractures;
Anesthesia
Not yet
Rec
24
Dynamic Internal Fixation of
NCT00779948
INTUIT Hip Fracture Outcome
Study
NCT00595634
Bipolar H.A Versus Trochanteric
Antegrade Nail for Treatment of
Displaced Subcapital Femoral
Fractures
study
NCT01181037
Bisphosphonate Users
Radiographic Characteristics of the
Hip (BURCH) Study
Prospective study
NCT01360099
Femoral Neck
Fracture
Rec
150
Unstable
Intertrochanteric Hip
Fractures
Rec
Displaced Subcapital
Femoral Fracture
Osteoporosis; Bone
Diseases, Metabolic;
Hip Fractures
Sen Jan-12 Jan-13 University of
Nottingham;
Nottingham
University
Hospitals NHS
Trust; Brighton
and Sussex
University
Hospitals NHS
Trust
Adt Dec-08 Dec-12 Aesculap AG
Sen
125
Adt Jan-08 Dec-12 Smith &
Sen
Nephew, Inc.
Rec
200
Adt Jun-10 Apr-12 Meir Medical
Sen
Center
Rec
900
Adt May-11 Jan-12 National Institute http://ClinicalTrials.gov/show/NCT01360099
Sen
of Arthritis and
Musculoskeletal
and Skin
Diseases
160
Waiting Time to Operation for Hipfracture Patients
NCT01488812
Epidemiology of Aeromedical
Evacuation
NCT01071382
Timing of Orthopaedic Surgery in
the Multiply-injured Patient:
Development of a Protocol for
Early Appropriate Care
Prospective study
NCT00888160
Economic Aspects Associated
With the Implementation of an
Orthogeriatric Setting in a General
Hospital
NCT00860132
Hip-fracture
Comp
Apoplexy; Femoral
Comp
Neck Fracture;
Myocardial
Infarction;
Subarachnoid
Hemorrhage;
Polytrauma
Unstable Pelvic Ring Rec
Fracture; Unstable
Acetabulum
Fracture; Femur
Fracture
Hip Fracture
576 Child Jun-10 Dec-10 Danderyd
Adt
Hospital
Sen
504 Child Feb-10 Feb-10 Ruhr University http://ClinicalTrials.gov/show/NCT01071382
Adt
of Bochum;
Sen
Workers'
Samaritan
Federation
Germany
Child Sep-10 Apr-09 MetroHealth
Adt
Medical Center
Sen
Not yet 2000 Adt May-09 Mar-09 Sheba Medical
Rec
Sen
Center
Recruit
n
URL
Active
60
A8C: ARTHROPLASTY
Title
Interventions
Conditions
CT ID
Behavioural
A pilot randomised controlled trial Pre-surgery home
Primary THR
of occupational therapy to optimise based occupational
recovery for patients undergoing intervention; Jospital
primary total hip replacement for based usual care
osteoarthritis
RCT
ISRCTN38381590
161
Age Start
(Grp) Date
End Sponsors
Date
Adt Feb-12 Jan-13 University of
Sen
Birmingham
(UK)
Comparison of Ways to Prepare
Patients for Decisions About Joint
Replacement Surgery
Phase III: RCT
NCT00911638
Device
Cementless New Alumina-zirconia
Ceramic Bearing Total Hip
Arthroplasty (THA) in Asian
Patients
NCT00935519
A Multi-centre Study to Assess the
Silent Hip™ in Primary Total Hip
Replacement Surgery
study
NCT01383824
Zimmer Continuum Metal on
Polyethylene (MoP) PostMarket
Clinical Followup (PMCF) Study
Prospective study
NCT01307384
Behavioral: Patient
decision aid and
referral onward.;
Behavioral: Patient
education and
referral onward
Osteoarthritis;
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Device: 4th
generation ceramic
bearing composite
ceramic bearing
Arthroplasty,
Replacement, Hip
Active,
NR
340 Child May-08 Jan-12 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00911638
Adt
Research
Sen
Institute
(Canada)
Rec
310 Child May-09 Dec-30 Seoul National
Adt
University
Sen
Bundang
Hospital
Device: Silent™ Hip Primary Arthritis;
Secondary Arthritis
Rec
500 Child Jan-11 Jul-27 DePuy
Adt
International
Device:
Continuum(R) Metal
on Polyethylene
Acetabular System
Rec
300
Adt Mar-11 Dec-24 Zimmer, Inc.
Sen
Rec
150
Adt Jan-11 Nov-22 Biomet, Inc.
Sen
Rec
125
Adt Jun-08 Jul-22 Exactech
Sen
Patients Receiving
Primary Hip
Arthroplasty Using
the Continuum Metal
on Polyethylene
Acetabular System
A Multicentre Trial to Compare
Device: Ceramic on Arthroplasty,
Two Articulating Bearing Surfaces metal articulating
Replacement, Hip
as Used in Cementless Primary
bearing surface
Hip Arthroplasty
study
NCT01247038
Post Approval Study: NOVATION Device: Novation
Total Hip
Ceramic Articulation Hip System Ceramic
Replacement (NonPhase IV: Single group
inflammatory)
study
NCT00715143
162
CoMplete™ Acetabular Hip
Device: Total hip
System
replacement
study
NCT01543230
A Study on M2a Magnum Total Hip Device: Metal-onArthroplasty
Metal Articulation;
Device: Metal-onNCT01010763
Metal Acetabular
System
A Study to Assess the Long-term Device: SmartSet®
Performance of SmartSet® HV
HV bone cement;
and SmartSet® GHV Bone
Device: SmartSet®
Cements in Primary Total Hip
GHV bone cement
Replacement
study
NCT00872066
A randomised, prospective, single
blind study comparing a standard
metal on polyethylene cemented
socket in primary hip replacement
versus an uncemented ceramic on
ceramic bearing socket in patients
under 65 years old
RCT
ISRCTN53483743
Joint Disease
Invite
250
Adt Feb-12 Feb-22 DePuy
Sen
Orthopaedics
Active,
NR
184
Adt Nov-09 Dec-21 Biomet, Inc.;
Sen
Biomet Japan,
Inc.
Rheumatoid Arthritis; Active,
Osteoarthritis; PostNR
traumatic Arthritis;
Collagen Disorders;
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
Uncemented ceramic Hip replacement
Active
on ceramic bearing;
cemented socket
with a metal on
polyethylene
243
Adt Mar-06 Nov-21 DePuy
Sen
International
322
Adt Mar-05 Mar-20 Department of
Health (UK)
Degenerative Joint
Disease; Avascular
Necrosis
163
A Multi-centre Study to Assess the Device: Summit
Tapered Hip System
Summit™ Hip in Primary Total Hip
Replacement
study
NCT00208390
ArCom® and ArComXL®
Polyethylene Data Collection
Prospective study
NCT00565786
Trident® Tritanium™ Acetabular
Shell Revision Study
NCT00535626
An Electronic Data Capture Study
to Assess the Long-term
Performance of the DePuy
PROXIMA™ Hip in Primary Total
Hip Replacement
study
NCT01134445
Multi-Centre Study to Assess the
DePuy ASR™ System in
Resurfacing and Primary Total Hip
Replacement
NCT00872547
Adt Mar-03 Dec-18 DePuy
Sen
International
150 Child Jul-04 Mar-17 Biomet
Adt
Orthopedics,
Sen
LLC
Active,
NR
244
Adt Nov-06 Dec-16 Stryker
Sen
Orthopaedics
Rec
300
Adt Feb-10 Dec-15 DePuy
Sen
International
624
Adt Sep-06 Jun-15 DePuy
International
Collagen Disorders;
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
Arthroplasty,
Active,
Replacement, Hip
NR
293
Device: ArCom®
Polyethylene;
Device: ArComXL®
Polyethylene
Device: Trident®
Arthroplasty,
Tritanium™
Replacement, Hip
Acetabular Shell
Device: DePuy
Proxima™ Hip
Avascular Necrosis;
Traumatic Femoral
Fractures;
Congenital Hip
Dysplasia
Device: DePuy
ASR™ Hip System;
Device: DePuy
ASR™ XL Head /
ASR™ Acetabular
Cup System
Collagen Disorders;
Avascular Necrosis;
Nonunion of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
164
A Two Centre Study to Assess the Device: Pinnacle
Acetabular Cup
Pinnacle™ Cup With a Metal-on- System
Metal Bearing in Primary Total Hip
Replacement
study
NCT00208364
Collagen Disorders;
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
Total Hip
Active
Arthroplasty
Periprosthetic bone mineral
Metha short stem
density (BMD) around two different (monoblock with
stems in total hip arthroplasty
130° CCD angle and
Observational, cohort study
0° ante-, retrotorsion)
ISRCTN54967983
or the Bicontact stem
(AESCULAP AG,
Tuttlingen, Germany)
A Two Centre Study to Assess the Device: C-Stem™
Stability and Long-term
AMT Femoral
Osteoarthritis; PostPerformance of the C-Stem™ AMT Component
in a Total Primary Hip
(standard and high Collagen Disorders;
Replacement
off-set variants)
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
study
of Femoral
NCT00872573
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis.
Omnifit Hydroxylapatite (HA) Hip Device: Omnifit HA Arthroplasty,
Active,
Outcomes Study
Hip Stem
Replacement, Hip
NR
NCT00958347
Randomised trial of hip fractures Hemiarthroplasty
Hip fracture; Hip
Active
treated with two different types of method 1;
Replacement
hip replacements
hemiarthroplasty
RCT
method 2
ISRCTN04635269
200
Adt Apr-04 Mar-15 DePuy
Sen
International
50
Adt Jun-06 Dec-14 German
Sen
Research
Council
50
Adt
Sen
262
Adt Oct-87 Dec-14 Stryker
Sen
Orthopaedics
600
Adt Nov-06 Nov-14 Department of
Sen
Health (UK)
165
Jul-06 Dec-14 DePuy
International
Accolade TMZF Hip Stem Study
NCT00957658
RCT of Ceramic Bearing Primary
Total Hip Arthroplasty
study
NCT01522014
Device: Accolade
TMZF Stem
Arthroplasty,
Replacement, Hip
Active,
NR
249
Adt Mar-06 Jun-14 Stryker
Sen
Orthopaedics
Device: Secure-Fit™ Total Hip
Active,
arc-deposited
Replacement
NR
Hydroxylapatite (HA)
shell - surface
ceramic and an
Alumina Bearing
Couple (ABC)
ceramic insert and
Ceramic C-taper
head; Device:
Secure-Fit™ arcdeposited
hydroxylapatite shell,
a Crossfire® insert
and a Ceramic Ctaper head
Encore Revelation Hip Stem
Device: Revelation Osteoarthritis, Hip;
Invite
Hip Stem
Complications;
NCT01514318
(Revelation)
Arthroplasty
A Multi-centre Study to Assess the Device: DePuy
Proxima™ Hip
DePuy PROXIMA™ Hip in Primary
Total Hip Replacement
Avascular Necrosis;
Traumatic Femoral
Fractures;
study
Congenital Hip
NCT00208455
Dysplasia.
Ceramic-on-Ceramic Total Hip
Device: THA with
Hip Arthrosis
Rec
Arthroplasty and Squeaking:
ABG II / Trident;
Influence of Component Design
Device: THA with
RCT
CLS / Trilogy
NCT01420900
The Efficacy and Cost Analysis of Device: Hemovac
Total Joint
Rec
Arthroplasty; Hip,
Reinfusion Drains Versus
drain; Device:
Knee
Tranexamic Acid in Total Joint
OrthoPAT drain;
Arthroplasty
Drug: Tranexamic
acid
NCT01514474
92
Adt Nov-97 Jun-14 University of
Alberta; Stryker
Canada
39
Adt Feb-12 Feb-14 Encore Medical, http://ClinicalTrials.gov/show/NCT01514318
Sen
L.P.
184
Sen
International
204
Adt Sep-11 Oct-13 Vejle Hospital
234
Adt Jan-12 Jun-13 OrthoCarolina
Sen
Research
Institute, Inc.
166
Post-approval Study of the
DURALOC® Option Ceramic-onCeramic Hip Prosthesis System
study
NCT00546598
Efficacy of a New Resurfacing Hip
Prosthesis
study
NCT00391937
A Single Centre Study to Assess
the Long-term Performance of the
Pinnacle™ Cup With a Ceramicon-ceramic Bearing in Primary
study
NCT00872222
Prediction of Pain in Total Hip
Arthroplasty
NCT01324375
Device: Total hip
replacement/arthropl
asty; Device: Hip
replacement/arthropl
asty
Device: Articular
Surface
Replacement (ASR)
hip prosthesis
Device: Pinnacle™
Acetabular System
Non-inflammatory
Joint Disease;
Osteoarthritis;
Avascular Necrosis;
Congenital Hip
Dysplasia; Posttraumatic Arthritis
Osteoarthritis, Hip
Active,
NR
250
Adt Jan-06 May-13 DePuy
Sen
Orthopaedics
Rec
150
Adt
Collagen Disorders;
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
of Femoral
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
Pain, Postoperative
Rec
200
Adt Nov-06 Jan-13 DePuy
Sen
International
60
Adt Mar-11 Dec-12 Hvidovre
Sen
University
Hospital
345
Adt
Sen
Device: heat pain
test (Modular
Sensory Analyzer,
Somedic AB, Horby,
Sweden).
Safety and Effectiveness Study of Device: Reflection
Osteoarthritis
the Reflection Ceramic Acetabular Ceramic-Ceramic
System
Total Hip
Replacement;
Device: Reflection
FSO V Total Hip
NCT00663351
Replacement
Active,
NR
167
Oct-06 Mar-13 Erasmus
Medical Center;
Johnson &
Johnson
38322 Dec-12 Smith &
Nephew, Inc.
Analysis of Crosslinked and
Conventional Polyethylene
Explants
NCT01484002
Device: Total hip
arthroplasty
Osteoarthritis
Invite
60
Unipolar or Bipolar
Device: Unipolar hip
Hemiarthroplasty in the Treatment hemiarthroplasty;
of Displaced Femoral Neck
Device: Bipolar hip
Fractures.
hemiarthroplasty
RCT, efficacy study
NCT00746876
A Prospective Study to Evaluate Device: Vitagel
the Effectiveness of a Haemostatic
Agent in Primary Unilateral Total
Hip Arthroplasty
NCT01285024
Clinical Study Evaluating an
Device: Acetabular
Acetabular Cup System After Total cup
Hip Replacement
NCT00306930
A Five-Year Metal-on-Metal
Device: Metal-onRetrospective Clinical Study
metal primary total
hip arthroplasty
NCT01481896
(DePuy )
Hip Fractures
Active,
NR
30
Rec
110
Osteoarthritis
Invite
131
RCT Comparing Ion Levels and
Device: A Class
Clinical Outcomes of A-Class BFH BFH; Device: Metal
to Metal on Polyethylene Total Hip on Polyethylene
Replacement
Phase IV: RCT
NCT00911599
Hip Joint;
Osteoarthritis;
Arthroplasty
Rec
60
Arthritis
Adt Dec-11 Dec-12 Anderson
Sen
Orthopaedic
Research
Institute;
Orthopaedic
Biomechanics
and Biomaterials
Laboratory at
Massachusetts
General
Hospital; DePuy
Orthopaedics
Sen Sep-09 Dec-12 Sykehuset Asker http://ClinicalTrials.gov/show/NCT00746876
og Baerum;
Ullevaal
University
Hospital
Adt Dec-10 Oct-12 The Cleveland http://ClinicalTrials.gov/show/NCT01285024
Sen
Clinic; Orthovita
Osteoarthritis;
Active, 1500 Child Oct-00 Jun-12 DePuy
Rheumatoid Arthritis; NR
Adt
Orthopaedics
Sen
Necrosis; Acute
Fracture
168
Adt Dec-11 Jun-12 Anderson
Sen
Orthopaedic
Research
Institute; DePuy
Orthopaedics
Adt Aug-06 May-12 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00911599
Sen
Research
Institute; Wright
Medical
Technology
Restoration® Modular Revision
Device: Restoration Arthroplasty,
Hip System Post Market Study
Modular Revision Hip Replacement, Hip
System
NCT00962013
Comparing Total Hip Arthroplasty Device: Total hip
Hip Fractures;
and Hemi-Arthroplasty on Revision arthroplasty; Device: Femoral Neck
Surgery and Quality of Life in
Hemi-arthroplasty
Fractures
Adults With Displaced Hip
Fractures (The HEALTH Study)
NCT00556842
A Comparison of Two Total Hip
Device: ReCap, Hip Osteoarthrosis
Replacements: Hip Resurfacing
resurfacing system,
System Versus MalloryBiomet
Head/Exeter
study
NCT00116948
Trident X3 Polyethylene Insert
Device: Trident X3 Arthroplasty,
Study
Polyethylene Insert Replacement, Hip
NCT00958191
Study Comparing Marathon
Device: Total Hip
Osteoarthritis;
Polyethylene and Enduron
Replacement
Arthritis; Joint
Polyethylene Acetabular Liners
Diseases;
Used in Total Hip Arthroplasty
Musculoskeletal
RCT
Diseases;
NCT01121146
Rheumatic Diseases
Metal-metal Articulations Versus Device: articular
Osteoarthritis, Hip
Standard 28 mm Cementless Total surface replacement
Hip Arthroplasty
ASR, DePuy; Device:
ReCap/Magnum
NCT01113762
modular head,
Biomet; Device:
Bimetric stem,
mallory/head cup, 28
mm ceramic head,
Biomet; Device: 28
mm CrCo head,
Trilogy CH cup,
VerSys Fiber
stem,Zimmer)
Active,
NR
144
Adt Jan-04 Apr-12 Stryker
Sen
Orthopaedics
Rec
306
Adt Mar-09 Mar-12 Boston
Sen
University (US)
Active,
NR
50
Adt
Active,
NR
240
Adt May-05 Jan-12 Stryker
Sen
Orthopaedics
Active,
NR
236 Child Dec-98 Dec-11 Anderson
Adt
Orthopaedic
Sen
Research
Institute; DePuy
Orthopaedics
Active,
NR
71
169
Jan-05 Jan-12 University of
Aarhus
(Denmark)
Adt Feb-07 Nov-11 University of
Southern
Denmark;
Ministry of the
Interior and
Health,
Denmark;
Region Sealand;
Biomet, Inc.;
DePuy
Orthopaedics;
ALS Laboratory
Group
Study to Assess the Stability,
Device: DePuy
Osteoarthritis
Efficacy and Safety of the Silent™ Silent™ Hip femoral
Hip Prosthesis in Primary Total Hip prosthesis
Replacement
study
NCT00894140
Scan Hip Evaluation
Device: Metal on
Hip Arthroplasty
metal hip
NCT01349179
arthroplasty operated
on 2002
A Multi-centre Study to Assess the Device: Pinnacle
Acetabular System Osteoarthritis; PostPinnacle™ Cup With a
Polyethylene-on-metal Bearing in
Collagen Disorders;
Primary Total Hip Replacement
Avascular Necrosis;
Traumatic Femoral
Fractures; Nonunion
study
of Femoral
NCT00208429
Fractures;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis.
A Randomised Single Centre
Device: Smartset HV Osteoarthritis; PostStudy to Compare the Long-term Bone Cement;
Performance of SmartSet® HV
Device: Palacos R Avascular Necrosis
and Palacos® R Bone Cements in
study
NCT00208403
Metal on Metal Versus Ceramic on Device: Total Hip
Joint Diseases
Metal Hip Replacement
Replacement;
Phase IV: RCT, safety/efficacy Device: Total hip
study
replacement
NCT00208494
Active,
NR
41
Adt
Jan-03 Sep-11 DePuy
International;
Johnson and
Johnson Medical
Comp
100 Child Dec-10 Sep-11 University
Adt
Hospital,
Sen
ClermontFerrand
Sep-11 DePuy
Wdrwn 200 Adt
Sen
International
Active,
NR
36
Adt Oct-02 Sep-11 DePuy
Sen
International
Comp
390
Adt Aug-05 Jun-11 DePuy
Sen
Orthopaedics
170
Bimetric-10: Investigation of
Patients Who Have Underwent
Total Hip Arthroplasty With a
Cemented Bi-Metric Stem
NCT00192699
A Short Metaphyseal Fitting Total
Hip Arthroplasty in Young and
Elderly Patients
Phase IV: RCT
NCT01345097
Use of Knotless Suture for Closure
of Total Hip and Knee
Arthroplasties
RCT, efficacy study
NCT00834483
28 mm Ceramic-on-Ceramic
Acetabular Cup Total Hip
Replacement Study
study
NCT00208507
ABC/Trident Ceramic Post
Approval Study
NCT00960206
Prevena™ Incision Management
System Over Primarily Closed Hip
and Knee Incisions in Patients
Immediately Post Total Hip and
Knee Arthroplasty
assignment
NCT01380665
A Clinical Investigation of
Recovery Following Hip
Resurfacing or Total Hip
Arthroplasty
assignment
NCT00585988
Device: Bimetric
femoral stem
Osteoarthrosis
Comp
100
Adt Jan-04 Apr-11 Northern
Sen
Orthopaedic
Division,
Denmark
Device: Total Hip
Arthroplasty
Osteonecrosis;
Osteoarthritis
Comp
200
Adt May-04 Mar-11 Ewha Womans
Sen
University
Device: Knotless
Primary Knee
Active,
suture for wound
Arthroplasty; Primary NR
closure; Device:
Hip Arthroplasty
Layered traditional
wound closure
(monocryl)
Device: 28 mm
Joint Diseases
Comp
ceramic head on
ceramic acetabular
liner.; Device: 28 mm
ceramic head on
polyethylene liner
Device: Ceramic
Arthroplasty,
Comp
Post Approval
Replacement, Hip
200
Adt Feb-09 Jan-11 Rush University http://ClinicalTrials.gov/show/NCT00834483
Sen
Medical Center
264
Adt Apr-03 Dec-10 DePuy
Sen
Orthopaedics
518
Adt Mar-03 Oct-10 Stryker
Sen
Orthopaedics
Device: Prevena
Linear or Emi-linear
Incisional
Incisions; Total Hip
Management System Arthroplasty; Total
Knee Arthroplasty
100
Adt Oct-09 Oct-10 KCI USA, Inc.
Sen
0
Adt Jun-07 Sep-10 Biomet
Sen
Orthopedics,
LLC
Device: Hip
Resurfacing System;
Device: M2aMagnum™ Large
Metal Articulation
Term
Osteoarthritis;
Wdrwn
Arthritis; Traumatic
Arthritis
171
Evaluation of the Efficacy of the
Device: Aquamantys; Blood Loss
Comp
Bipolar Sealer Aquamantys 6.0 in Procedure: Standard
Patients Undergoing Total Hip
Electrocautery
Arthroplasty
NCT01448967
Comparison in Need for Bank
Device: Sangvia®
Arthroplasty,
Comp
Blood Between Patients
System
Replacement, Hip;
Undergoing Total Hip Surgery That
Blood Transfusion;
Either Receive Their Own Blood
Blood Transfusion,
Back or Not
Autologous
RCT, efficacy study
NCT00822588
Total Hip Replacement With the
Device: Answer® hip Osteoarthritis, Hip;
Term
Answer® Hip Stem and
stem; Device:
Traumatic Arthritis of
Ranawat/Burnstein® Shell Using Answer® hip stem Hip
Simplex® or Palacos® Bone
Cement
assignment
NCT00588861
A Comparison of a Resurfacing
Device: Hip
Osteoarthritis
Comp
Hip System to Standard Total Hip Resurfacing System
Arthroplasty
study
NCT00253877
Intravenous Ferric Carboxymaltose Drug: Ferinject 50
(Ferinject) in Patients Undergoing mg/ml; Drug: NaCl
Orthopaedic Surgery
0.9%
study
NCT01345968
Effect of Denosumab on
Drug: Denosumab;
Inflammatory Osteolytic Lesion
Other: Placebo
Activity in Total Hip Arthroplasty
Phase II: RCT
NCT01358669
Anemia; Knee
Replacement; Hip
Replacement
Revision Surgery of
Total Hip
Arthroplasty
140
Adt Nov-06 Jun-10 Salient Surgical http://ClinicalTrials.gov/show/NCT01448967
Sen
Technologies;
The Cleveland
Clinic
227
Adt May-09 Jun-10 Astra Tech AB
Sen
400
Adt Sep-02 May-10 Biomet
Sen
Orthopedics,
LLC
200
Adt
Sen
Rec
140
Adt Jun-11 Oct-15 University
Sen
Hospital
Muenster; Vifor
Pharma
Not yet
Rec
30
Adt Jan-12 Jan-15 Sheffield
Sen
Teaching
Hospitals NHS
Foundation
Trust; Amgen;
NIHR
Musculoskeletal
BRU
172
Jul-03 May-10 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00253877
Research
Institute; Wright
Medical
Technology
Effect of Zoledronic Acid on
Drug: Zoledronic acid Osteoporosis
Femoral Bone Loss Following
study
NCT01267279
Rifampin Combination Therapy
Drug: RifampinProsthesis-related
Versus Monotherapy in Early
combination therapy; Infections;
Staphylococcal Infections After
Drug: Monotherapy Staphylococcal
Total Hip and Knee Arthroplasty
Infections
NCT00423982
Hydroxyethyl Starch and Renal
Drug: Voluven 60
Arthroplasty,
Function After Hip Replacement
mg/ml; Drug: Sodium Replacement, Hip
Surgery
Chloride 9 mg/ml
NCT01486576
Drug: Gabapentin
Postoperative Pain;
spine, hip or knee
replacement.
Surgical Patients
study
NCT00221338
Safety and Efficacy of IM Injections Biological: PLX-PAD Total Hip
of PLX-PAD for the Regeneration low dose; Biological: Arthroplasty; Muscle
of Injured Gluteal Musculature
PLX-PAD high dose; Injury
After Total Hip Arthroplasty
Biological: Placebo
study
NCT01525667
A comparison of the need for
bupivicaine via the Primary hip
opiate pain relief medication after pain pump device
arthroplasty
elective hip replacement surgery into the tissues
between patients given Local
surrounding the new
Anaesthetic Infiltration to the new joint; placebo via the
joint and then an infusion of either pain pump device
local anaesthetic or placebo
into the tissues
around the new joint
surrounding the new
RCT (placebo), efficacy study
joint
ISRCTN24271997
Active,
NR
Rec
66
Child Jan-05 Jan-15 Spokane Joint
Adt
Replacement
Sen
Center
100 Child Apr-06 Dec-14 Oslo University
Adt
Hospital
Sen
Not yet
Rec
40
Adt Dec-11 Dec-14 Holstebro
Sen
Hospital
Rec
312
Sen
California, San
Francisco
Not yet
Rec
18
Adt Apr-12 Dec-13 Pluristem Ltd.
Sen
Active
70
Adt Oct-11 Oct-13 Leeds Teaching http://www.controlledSen
Hospitals NHS trials.com/ISRCTN24271997
Trust (UK)
173
Psoas Compartment Block Versus
Fascia Iliaca Block After Total Hip
Arthroplasty
RCT, efficacy study
NCT01378949
Oxycodone Versus Intravenous
Morphine for Postoperative
Analgesia After Hip Surgery
study
NCT01536301
Study To Investigate The
Effectiveness Of Pregabalin For
Management Of Patients
Undergoing Total Hip
Replacement
study
NCT00905437
A Study of LY2495655 in Older
Patients Undergoing Elective Total
Hip Replacement
study
NCT01369511
An international study to assess
the effects of strontium ranelate in
the reduction of bone loss around
the metal implant, in patients with
hip prosthesis
RCT
ISRCTN15928978
Treatment of Patients Undergoing
Primary Unilateral Elective Total
Knee or Hip Replacement With
Dabigatran Etexilate
Phase IV: RCT,
pharmacokinetics/dynamics
study
NCT01184989
Drug: Bupivacaine;
Drug: Morphine
Pain
Drug: Standard Care Arthroplasty,
morphine
Replacement, Hip
hydrochloride; Drug:
Oxycodone
Not yet
Rec
90
Not yet 246
Rec
Adt Sep-11 Sep-13 Hillel Yaffe
Sen
Medical Center
Adt Mar-12 Sep-13 Centre
Sen
Hospitalier
Universitaire de
Nīmes
Drug: Placebo; Drug: Pain, Perioperative
Pregabalin
Rec
256
Adt Nov-09 Jun-13 Pfizer
Sen
Drug: LY2495655;
Drug: Placebo
Total Hip
Replacement
Rec
340
Adt
Sen
2g of strontium
ranelate; placebo
Total Hip
Replacement
Active
126
Adt May-11 Apr-13 Institut de
Recherche
Internationales
Servier (France)
Drug: Dabigatran
etexilate
Arthroplasty,
Replacement, Knee;
Venous
Thromboembolism
Rec
100
Adt Aug-10 Apr-13 Boehringer
Sen
Ingelheim
Pharmaceuticals
174
Jul-11 May-13 Eli Lilly and
Company
Daptomycin Use for Antimicrobial Drug: Daptomycin;
Prophylaxis in Methicillin Resistant Drug: Vancomycin
Staphylococcus Aureus (MRSA)
Colonized Adult Patients
Undergoing Primary Elective Hip
or Knee Arthroplasty
NCT01196169
Study to Observe Safety of Xarelto Drug: Rivaroxaban
in VTE Prophylaxis After Elective (Xarelto, BAY59TKR or THR
7939)
NCT01523418
Rotational Thromboelstometry
Drug: Pentaspan,
(ROTEM) change_colloid_total Hip voluven, volulyte
Replacement Arthroplasty
RCT
NCT01512628
Russian Non-Interventional Study Drug: Rivaroxaban
on Compliance of Venous
(Xarelto, BAY59Thromboembolism (VTE)
7939)
NCT01444586
Xarelto for VTE Prophylaxis After Drug: Rivaroxaban
Hip or Knee Arthroplasty
(Xarelto, BAY59Prospective, cohort study
7939); Drug:
NCT00831714
Standard care
treatment for VTE
prophylaxis
Effect of Spinal Ketorolac on
Drug: ketorolac
Mechanical Hypersensitivity After a tromethamine
opthalmic solution;
Drug: placebo
NCT00621530
Prophylaxis Against DVTs After
Primary Hip and Knee
Replacement Surgery
NCT00767559
Staphylococcal
Infections;
Methicillin-resistant
Staphylococcus
Aureus
Prophylaxis,
Thromboembolism,
Venous; Total Knee
Replacement; Total
Hip Replacement
Avascular Necrosis
of Hip; Total Hip
Replacement
Arthroplasty
Rec
100
Not yet 500
Rec
Rec
54
Adt Oct-10 Apr-13 Mountain Home http://ClinicalTrials.gov/show/NCT01196169
Sen
Research &
Education
Corporation;
East Tennessee
State University;
Cubist
Pharmaceuticals
Adt Jun-12 Apr-13 Bayer
Sen
Adt Jan-12 Jan-13 Seoul National
Sen
University
Bundang
Hospital
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Rec
2522 Adt Oct-11 Dec-12 Bayer
Sen
Venous
Thromboembolism
Rec
15000 Adt
Hip Arthroplasty
Drug: warfarin; Drug: Pulmonary
Fondaparinux:; Drug: Embolism
warfarin
Feb-09 Nov-12 Bayer
Sen
Active,
NR
100
Active,
NR
330
175
Adt Mar-08 Oct-12 James C.
Sen
Eisenach, M.D.;
National Institute
of General
Medical
Sciences
(NIGMS)
Adt Nov-08 Oct-12 The New
Sen
England Baptist
Hospital
Low Dose Extended-release
Drug: Extended
Hip Arthroplasty
Epidural and Lumbar Plexus Block Release Epidural
Compared to Lumbar Plexus Block Morphine (EREM);
for Total Hip Resurfacing
Drug: Placebo
RCT, efficacy study
NCT00934661
Single IV Administration of TB-402 Drug: TB-402; Drug: Prophylaxis of
for Prophylaxis of Venous
Rivaroxaban; Drug: Venous
Thromboembolic Events (VTE)
TB-402
Thromboembolic
After Total Hip Replacement
Events
Surgery
study
NCT01344954
Total Hip Arthroplasty: Multiple
Drug: Ropivacaine; Pain, Postoperative
Blocks by UltraSound
Drug: Ropivacaine;
RCT, efficacy study
Device: Ultrasound;
NCT01276925
Procedure:
Peripheral nerve
blockade; Drug:
Saline; Procedure:
Total hip
arthroplasty; Drug:
Bupivacaine
Effect of Reversing Muscle
Drug: Sugammadex; Neuromuscular
Relaxation With Sugammadex
Drug: neostigmine Blockade;
Compared With Usual Care on
and glycopyrrolate or Arthroplasty,
Bleeding Risk in Patients on Blood atropine; Drug:
Replacement, Hip;
Thinners Undergoing Major Joint Placebo
Arthroplasty,
Surgery (P07038/MK-8616-059)
Replacement, Knee;
Phase III: RCT, safety study
Blood Coagulation;
NCT01422304
Antithrombotic
Agents
The Effect of Periarticular MultiDrug: periarticular
Femoral Neck
Drug Regimen on Pain After
injection of multidrug Fracture
Partial Hip Replacement
regimen; Drug: none
of medication
NCT01112436
preoperatively and
intraoperatively
Rec
60
Adt
Rec
600
Adt Apr-11 Jul-12 ThromboGenics; http://ClinicalTrials.gov/show/NCT01344954
Sen
BioInvent
International AB
Rec
81
Adt Aug-11 May-12 Bispebjerg
Sen
Hospital
Rec
800
Adt Oct-11 May-12 Schering-Plough http://ClinicalTrials.gov/show/NCT01422304
Sen
Rec
258 Child May-10 Apr-12 Chung-Ang
Adt
Univerisity
Sen
Hospital
176
Jan-10 Jul-12 Wake Forest
University; EKR
Therapeutics,
Inc
Use of Etoricoxib Compared to
Drug: Etoricoxib;
Diclofenac in the Perioperative
Drug: Diclofenac
Treatment of Patients After Total
Hip Arthroplasty
NCT01229774
Prevention of Heterotopic
Drug: Etoricoxib
Ossification With Arcoxia After
(Arcoxia)
NCT01022190
Evaluating the Effectiveness of 2 Drug: Duraprep
Surgical Skin Preparation Methods Surgical Solution
in Reducing Surgical Wound
Drainage After Total Hip or Knee
Replacement
RCT, efficacy study
NCT01097135
Postoperative Pain Relief
Drug: LIA; Drug: I/T
Following Total Hip Arthroplasty. A morphine
Comparison Between Intrathecal
Morphine (IM) and Local Infiltration
Analgesia (LIA)
study
NCT01281891
Topical Application of Tranexamic Drug: Tranexamic
Acid Reduces Postoperative Blood Acid; Drug: normal
Loss in Total Hip Arthroplasty
saline
RCT
NCT01260818
Coxarthrosis;
Arthroplasties Hip
Replacement;
Perioperative Blood
Loss
Rec
100
Sen
Regensburg;
Merck
Osteochondritis;
Ossification,
Heterotopic
Rec
42
Adt Dec-09 Jan-12 Radboud
Sen
University
Drainage
Rec
600
Adt Mar-10 Dec-11 Rothman
Sen
Institute
Orthopaedics;
3M
Primary
Osteoarthritis
Requiring Total Hip
Replacement
Rec
80
Adt Sep-09 Dec-11 University
Sen
Hospital Orebro
Hip Replacement;
Postoperative
Hemorrhage
Rec
100
Pradaxa (Dabigatran Etexilate)
VTE Prevention After Elective
Total Hip or Knee Replacement
Surgery
NCT01153698
Venous
Thromboembolism;
Arthroplasty,
Replacement
Term
167
Adt Dec-10 Dec-11 The First
Sen
Affiliated
Hospital,
Guangzhou
University of
Traditional
Chinese
Medicine
Adt Aug-10 Nov-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Drug: dabigatran
177
Postoperative Pain Control After
Hip Hemiarthroplasty: Intrathecal
Morphine vs Periarticular
Infiltration of Bupivacaine
NCT01219062
Use of Local Infiltration Analgesia
Following Total Hip Arthroplasty
NCT01344395
Use of Local Analgesia With
Epinephrine During Total Hip
Arthroplasty (THA)
NCT00980616
The Analgesic Efficacy of
Periarticular Infiltration of Local
Anaesthetic for Total Hip
Replacement
NCT01312077
Extended Prophylaxis Comparing
low molecular weight heparin
(LMWH) to Aspirin in Total hip
arthroplasty
RCT
ISRCTN11902170
Dabigatran Etexilate Compared
With Enoxaparin in Prevention of
Venous Thromboembolism (VTE)
Following Total Hip Arthroplasty
study
NCT00657150
Morphine COnsumption in Joint
Replacement Patients, With and
Without GaBapentin Treatment, a
RandomIzed ControlLEd Study
RCT, efficacy study
NCT00889148
Drug: Morphine or
Femoral Neck
0.25 % Bupivacaine Fracture
Rec
60
Adt Sep-10 Sep-11 Mahidol
Sen
University
Drug: ropivacaine
and ketorolac; Drug: Pain
Ketorolac
Rec
80
Drug: ropivacaine,
physical serum and
adrenalin
Arthroplasty,
Replacement, Hip
Rec
150
Adt Mar-10 Sep-11 University of
Sen
Aarhus;
Lundbeck
Foundation
Adt Sep-09 Sep-11 University
Sen
Hospital,
ClermontFerrand
Drug:
Levobupivacaine;
Drug: Intrathecal
morphine
Total Hip
Arthroplasty
Rec
50
Aspirin; Dalteparin;
Placebo
Elective total hip
arthroplasty
Comp 2222 Adt Sep-07 Mar-11 Dalhousie
Sen
University
(Canada)
Drug: Enoxaparin;
Drug: Dabigatran
etexilate
Venous
Thromboembolism
Comp 2055 Adt Mar-08 Feb-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Drug: Gabapentin;
Other: Placebo
Postoperative Pain;
Total Hip
Replacement
Comp
103
178
Adt Oct-10 Jun-11 Cork University http://ClinicalTrials.gov/show/NCT01312077
Sen
Hospital
Adt Oct-07 Feb-11 Hamilton Health http://ClinicalTrials.gov/show/NCT00889148
Sen
Sciences
Corporation
Dabigatran Etexilate in Extended Drug: dabigatran
Venous Thromboembolism (VTE) etexilate; Drug:
Prevention After Hip Replacement dabigatran etexilate;
Surgery
Drug: enoxaparin
NCT00168818
Effects of Methylprednisolone After Drug:
Methylprednisolone
NCT00968903
Management of Postoperative
Drug: Bupivacaine;
Pain After Total Hip Arthroplasty Drug: Placebo
Phase II/III: RCT
NCT01040273
Switching Drug Therapy for the
Drug: Rivaroxaban
Prevention of Blood Clot Formation
From Enoxaparin to Rivaroxaban
After Orthopedic Surgery for Either
Total Hip or Total Knee
Replacement
Phase III: RCT,
NCT01094886
Ketamine Associated With
Drug: KetamineMorphine PCA After Total Hip
Morphine; Drug:
Arthroplasty
Morphine; Drug:
RCT, efficacy study
Postoperative PCA
NCT00797264
of Ketamine and
morphine
A randomised controlled trial to
Injection of local
determine if local wound infiltration anaesthethic into
reduces chronic pain after lower
joint during joint
limb arthroplasty
replacement +
RCT
standard
ISRCTN96095682
anaesthetic;
standard anaesthetic
alone
Thromboembolism;
Arthroplasty,
Replacement, Hip
Comp 3494 Adt Nov-04 Jan-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
LOS; Postoperative
Pain; Postoperative
Nausea and
Vomiting; Sleeping
Quality; Fatigue;
Inflammatory
Response
Osteoarthritis of Hip
Comp
48
Not yet
Rec
Adt Apr-10 Jan-11 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Adt Dec-09 Dec-10 Chang Gung
Sen
Memorial
Hospital
Arthritis;
Comp
Osteoarthritis, Knee;
Osteoarthritis, Hip;
Thromboembolism
56
Adt Feb-10 Dec-10 Ortho-McNeil
Sen
Janssen
Scientific Affairs,
LLC
Arthroplasty,
Replacement, Hip
Rec
100
Adt Nov-08 Nov-10 Assistance
Sen
Paris
Hip replacement;
Knee replacement
Comp
600
Adt Nov-09 Sep-10 Southmead
Sen
Hospital (UK)
179
Treatment of Postoperative Pain
After Total Hip Arthroplasty Using
Intravenous Lidocaine Infusion
NCT01108562
Hemorrhage Risk Prescribed
Arixtra
NCT01064362
Drug: Lidocaine;
Postoperative Pain
Other: Normal Saline Management After
Total Hip
Arthroplasty
Drug: Fondaparinux
sodium; Drug: Low
molecular weight
heparin (LMWH)
Effect of Local Infiltration
Drug: Ropivacaine
Analgesia in Total Hip Arthroplasty
NCT00968955
Clinical Trial for Fibrin Sealant in
Knee Surgery
RCT, efficacy study
NCT00440921
A Study Evaluating Efficacy and
Safety of YM150 Compared to
Enoxaparin in Subjects
Undergoing Hip Replacement
Surgery
study
NCT00902928
Can Risedronate Prevent
Periprosthetic Bone Loss After
NCT00772395
Randomised controlled trial to
assess the difference of spinal
anaesthesia versus general
anaesthesia in hip replacement
surgery
RCT
ISRCTN36381516
Drug: Single donor
Allogenous Fibrin
Sealant
Knee Replacement
Surgery;
Haemorrhage;
Thrombosis,
Venous; Hip
Replacement
Surgery; Hip
Fracture Surgery
Post-operative Pain
Total Kneereplacement; Total
Hip-replacement
Drug: YM150; Drug: Venous
enoxaparin
Thromboembolism;
Arthroplasty,
Replacement, Hip
Drug: Risedronate;
Drug: Placebo
Bone Loss
Spinal anaesthesia; Hip fracture; Hip
General anaesthesia Replacement
Adt Feb-08 Sep-10 Loma Linda
Sen
University;
Charles Lee MD;
Michelle Schlunt
MD
Comp 1344 Adt Jan-10 Jun-10 GlaxoSmithKline http://ClinicalTrials.gov/show/NCT01064362
2
Sen
Wdrwn 110
Comp
120
Adt Sep-09 Jun-10 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Wdrwn 578 Adt Dec-08 Jun-10 Sanquin
Sen
Research &
Blood Bank
Divisions; MDM
Comp 1992 Adt Apr-09 Jun-10 Astellas Pharma http://ClinicalTrials.gov/show/NCT00902928
Sen
Inc
Active,
NR
78
Adt Apr-06 May-10 Danderyd
Sen
Hospital; SanofiAventis
Comp
600
Adt Apr-07 Apr-10 Peterborough
and Stamford
Hospitals NHS
Foundation Trust
(UK)
180
A Study of DU-176b, Prevention of
Patients After Total Hip
Arthroplasty
study
NCT01181167
Undergoing Elective Total Hip
Replacement Surgery
study
NCT00913120
Pharmacokinetic Study of the
Penetration of Ceftobiprole in the
Bone
Phase I: RCT, pharmacokinetics
study
NCT00771524
Drug: edoxaban;
Drug: enoxaparin
sodium
Comp
610
Adt May-09 Mar-10 Daiichi Sankyo http://ClinicalTrials.gov/show/NCT01181167
Sen
Inc.; Daiichi
Sankyo, Tokyo,
LTD.
Drug: YM150; Drug: Venous
Placebo; Drug:
Thromboembolism
Enoxaparin
Comp
610
Adt May-09 Mar-10 Astellas Pharma http://ClinicalTrials.gov/show/NCT00913120
Sen
Inc
Drug: Ceftobiprole
Comp
22
Adt May-09 Feb-10 Ortho-McNeil
Sen
Janssen
Scientific Affairs,
LLC
Rec
400
Adt Apr-04 Jun-22 University
Sen
Hospital of North
Norway
Rec
1000 Adt Nov-07 Oct-17 Massachusetts http://ClinicalTrials.gov/show/NCT00545285
Sen
General
Hospital; Biomet,
Inc.
Procedure
Primary Uncemented Partly TiProcedure:
coated Total Hip Prosthesis With Uncemented primary
and Without HA, and Alumina-on- total hip arthroplasty
alumina Articulation
NCT01118247
Prevention; Venous
Thromboembolism
Hip Replacement,
Total
Survival of the
Implants With
Revision as
Endpoint; Clinical
Performance With
HHS; Patients
Satisfaction With the
Hip Implant
Long-Term Multi-center Evaluation Procedure: Total Hip Osteoarthritis of Hip;
of E-Poly and Regenerex
Arthroplasty
Hip
assignment
NCT00545285
Minimal Invasive Surgery in Total Procedure: Total hip Hip Osteoarthritis
Hip Arthroplasty Patients; Short- replacement;
and Long Term Results
Procedure: Total hip
replacement;
NCT01506024
replacement
Rec
60
181
Child Sep-11 Sep-16 Norwegian
Adt
University of
Sen
Science and
Technology; St.
Olavs Hospital
Study of Antibiotic Spacer Design
to Treat Infection After Hip
Replacement
RCT, efficacy study
NCT01373099
Procedure:
Implantation of a
static, nonarticulating cement
spacer.; Procedure:
Implantation of an
articulating spacer.
Hemi Artificial Hipjoint Versus
Procedure: THA
Total Artificial Hipjoint
(Total hip
Phase IV: RCT, safety/efficacy arthroplasty) versus
study
Hemi
NCT01432691
(hemialloplastik)
Minimal Invasive Anterior
Procedure: TransApproach Versus Trans-gluteal
gluteal approach,
Approach for Hemi-arthroplasty in CLAS; Procedure:
Anterior minimal
invasive approach,
NCT01408693
AMIS
Cementless One-stage Revision of Procedure:
the Chronic Infected Hip
Cementless oneArthroplasty
stage surgical
revision
NCT01015365
Safety and Efficacy of the SL
Procedure: primary
PLUS and the SL PLUS MIA Hip total hip arthroplasty
Stem
study
NCT01435850
Anterolateral Versus Posterolateral Procedure:
Approach to the Fractured Hip
Anterolateral
Arthroplasty
approach
NCT01486641
Osteoarthritis; Hip
Infection; Prosthetic
Joint Infection;
Complications;
Arthroplasty,
Infection or
Inflammation;
Complications;
Arthroplasty
Optimized Treatment
Rec
80
Adt Aug-11 Aug-16 Rush University http://ClinicalTrials.gov/show/NCT01373099
Sen
Medical Center;
Thomas
Jefferson
University;
Central DuPage
Hospital
Rec
70
Sen Jun-10 Jun-15 Hvidovre
University
Hospital
Femoral Neck
Fracture
Rec
190
Adt Aug-11 Dec-14 University
Sen
Hospital, Basel,
Switzerland
Infection; Hip
Replacement
Arthroplasty
Rec
100
Sen
Aarhus
Joint Replacement;
Hip
Rec
90
Adt Apr-09 Apr-14 Smith & Nephew http://ClinicalTrials.gov/show/NCT01435850
Sen
Orthopaedics
AG
Femoral Neck
Fracture
Rec
160
Adt Feb-12 Jan-14 Sundsvall
Sen
Hospital
182
Importance of Restoring
Biomechanical Correct Hip
Anatomy During Total Hip
Arthroplasty
RCT, efficacy study
NCT01512550
Periprosthetic Bone Remodeling
Around a Short and a
Conventional Femoral Stem in
RCT, efficacy study
NCT01319227
Evaluation of Four Surgical
Techniques in Primary Total Hip
Arthroplasty
RCT, efficacy study
NCT01031732
Procedure: GF hip Osteoarthritis
guide; Procedure:
Stryker Navigation
System; Device:
ABG II modular
femoral component;
Device: ABG II
femoral component
Procedure: Hip
Hip Arthroplasty
replacement
Procedure: MIS-2
THA; Procedure:
MIS-WJ; Procedure:
MIS-AL THA;
Procedure: MIS-PL
THA
Follow up Study of Patients
Procedure: Total Hip
Undergoing Total Hip Arthroplasty Arthroplasty
CERAFIT® Grafted With Poly
Replacement
Sodium Styrene Sulfonate
NCT01454271
Prospective Randomized
Comparison of Bipolar
arthroplasty;
Hemiarthroplasty and Total Hip
Procedure:
Arthroplasty With Large Femoral Hemiarthroplasty
Heads for the Treatment of
Displaced Intracapsular Femoral
Neck Fractures in the Elderly
study
NCT01109862
A Comparison of Two Different
Procedure: Surgical
Surgical Techniques in Hip
approach (ReCap
Resurfacing Arthroplasty
Hip Resurfacing
RCT, efficacy study
System)
NCT00913679
Arthroplasty,
Replacement, Hip
Hip Arthroplasty
Replacement
Active,
NR
75
Adt Jan-10 Dec-13 Region Skane
Sen
Rec
50
Adt Oct-09 Dec-13 Danderyd
Sen
Hospital;
Johnson &
Johnson
Rec
120 Child Nov-09 Dec-13 Chang Gung
Adt
Memorial
Sen
Hospital;
Zimmer, Inc.
Not yet
Rec
50
Adt Dec-11 Dec-13 Laboratoire
Sen
Ceraver-Osteal
Femoral Neck
Fractures
Rec
80
Sen Apr-10 Dec-13 Wolfson Medical http://ClinicalTrials.gov/show/NCT01109862
Center
Osteonecrosis;
Femoral Neck
Fracture; Implant
Failure
Rec
50
Aarhus; Aarhus
University
Hospital; Biomet,
Inc.
183
A Trial Comparing Mini-posterior
Approach and Direct Anterior
Approach
RCT, efficacy study
NCT01024309
Procedure: MiniOsteoarthritis
Posterior surgical
approach for total hip
arthroplasty;
Procedure: Direct
Anterior surgical
approach for total hip
arthroplasty
Procedure: Hip
Hip Osteoarthritis
arthroplasty
Rec
112
Obesity's Impact on the Effect of
Rec
100
Hip Arthroplasty
NCT01496716
Benefit of Orthopedic Navigation in Procedure: Manual Osteoarthritis, Hip;
Rec
80
the ARThroplasty of the Hip
Intervention;
Arthritis,
Phase IV: RCT
Procedure:
Rheumatoid; Femur
NCT01496300
Navigated
Head Necrosis
Intervention
Study Comparing a Nerve Block Procedure:
Analgesia
Not yet 106
With Spinal Opiate to Provide Pain ultrasound guided
Rec
Relief for Hip Replacement
fascia iliaca block;
Surgery
Procedure: spinal
morphine
NCT01217294
Compaction Total Hip Arthroplasty Procedure: Bone
Coxarthrosis
Active, 20
(THA) Bilateral
preparation
NR
technique:
efficacy study
compaction;
NCT00317889
Procedure: Bone
preparation
technique: broaching
A Randomised Trial Comparing
Procedure: Minimally Osteoarthritis;
Rec
50
Anterior Versus Posterior
Invasive Anterior
Approach in Total Hip
Approach;
Replacement
Procedure: Standard
RCT, efficacy study
postero-lateral
NCT01106560
approach
Gait Analysis of Anterior Versus
Procedure: Anterior Osteoarthritis
Rec
64
Posterior Approach in
Approach;
Performance of Total Hip
Procedure: Posterior
Arthroplasty
Approach
assignment
NCT00951951
184
Adt Nov-09 Jun-13 OrthoCarolina
Sen
Research
Institute, Inc.
Sen
Aarhus
Adt Nov-11 Apr-13 Aesculap AG
Sen
Adt Apr-11 Apr-13 University of
Sen
Glasgow; NHS
Greater Glasgow
and Clyde
Adt Jan-04 Jan-13 Northern
Sen
Orthopaedic
Division,
Denmark
Adt Jan-10 Jan-13 Medacta
Sen
International SA
Adt Jun-09 Dec-12 Medacta USA; http://ClinicalTrials.gov/show/NCT00951951
Sen
Medacta
International SA
Compaction Total Hip Arthroplasty
(THA) Unilateral
RCT, efficacy study
NCT00318396
Procedure: Bone
Coxarthrosis
preparation
technique:
compaction;
Procedure: Bone
preparation
technique: broaching
Comparison of Hip Resurfacing to Procedure: Hip
Osteoarthritis;
Large Femoral Head Total Hip
replacement
Avascular Necrosis
Arthroplasty
efficacy study
NCT00175487
Comparison of Two Minimally
Procedure: hip
Osteoarthritis
Invasive Surgical Techniques for surgery
Hip Replacement
NCT00175461
A Telemedicine Solution for
Procedure: remote Quality of Life;
Remote Support of Rehabilitation, rehabilitation support Anxiety
for Patients Undergoing, Total Hip
Arthroplasty Surgery
NCT00969020
Evaluation of the Wear of Vitamin Procedure: Hip
Osteoarthritis of Hip;
E Treated Polyethylene
replacement
Components in Primary THA Using
Hip
RSA
NCT00551967
A Randomized Controlled Trial of Procedure: Waiting Osteoarthritis
Long Versus Short Wait For
time (access time to
Primary Total Hip and Knee
Total joint
Arthroplasty
replacement)
NCT00138892
Active,
NR
40
Adt
Sen
Active,
NR
108
Adt Sep-07 Dec-12 University of
British Columbia
Active,
NR
156
Sen
British Columbia
Rec
74
Rec
50
Child Sep-09 Nov-12 Regionshospital http://ClinicalTrials.gov/show/NCT00969020
Adt
et Silkeborg;
Sen
Caretech
Innovation;
Lundbeck
Foundation
Adt Oct-07 Oct-12 Massachusetts http://ClinicalTrials.gov/show/NCT00551967
Sen
General
Hospital; Biomet,
Inc.
Active,
NR
236
185
Dec-12 Northern
Orthopaedic
Division,
Denmark
Adt Aug-02 Oct-12 University of
Sen
British Columbia
Periprosthetic Bone Mineral
Density After Total Hip
Arthroplasty Performed Through a
Minimally Invasive Anterior
Approach (AMIS) With Either an
AMIStem or a Quadra Femoral
Component
RCT, efficacy study
NCT01285843
RSA for a Comparison of MIS vs.
Standard Exposure in Total Hip
Arthroplasty
RCT
NCT00405483
Mobility Assessment of Patients
With Total Hip Arthroplasty
assignment
NCT00664508
Procedure: Anterior Osteoarthritis;
Active,
Minimally Invasive
NR
Approach (AMIS)
Necrosis; Fracture of
the Femoral Neck or
Head; Congenital
Hip Dysplasia
40
Procedure: Min
Osteoarthritis
Invasive vs standard
exposure in hip
arthroplasty;
Procedure: Minimally
Invasive
Procedure: Motion Osteoarthritis;
analysis; Procedure: Arthroplasty; Hip
Motion analysis;
Replacement
Procedure: Motion
analysis
Active,
NR
100
Rec
30
Efficacy of Preoperative Education Procedure: Osteoarthritis of the
and Mini-invasive Surgery for Total preoperative
Hip
Hip Replacement
education and total
hip replacement
NCT00449228
Effect of Prophylactic Antibiotics Procedure:
Infection;
Arthroplasty; Hip;
on Intra-Operative Culture Results Prophylactic
Knee
Antibiotics;
NCT01174212
Procedure: Control
Antibiotics
The Influence of Anesthetic
Procedure: spinal
Primary Total Hip
Technique on Post-operative Pain anesthesia vs lumbar Arthroplasty
Scores and Range of Motion in
plexus block with
Primary Total Hip Arthroplasty
general anesthesia
NCT01359865
Child Sep-10 Sep-12 Medacta
Adt
International SA
Sen
Adt
Oct-05 Aug-12 Dalhousie
University;
Wright Medical
Technology
Adt Nov-07 Jul-12 Ottawa Hospital
Sen
Research
Institute;
Canadian
Institutes of
Health Research
Rec
215 Adt Apr-07 Jul-12 Assistance
Sen
Paris; Cochin
Hospital
Rec
200 Adt Jul-10 Jul-12 Rush University
Sen
Medical Center;
Rothman
Institute
Orthopaedics
Not yet 70 Child Jul-11 Jul-12 Milton S.
Rec
Adt
Hershey Medical
Sen
Center
186
Rec
80
Adt Apr-09 Apr-12 Assistance
Sen
Publique
Hopitaux De
Marseille
Rec
100
Procedure: Total hip Primary Arthrosis;
arthroplasty
Osteoarthritis
Active,
NR
50
Procedure: Bipolar
hemiarthroplasty;
Procedure: Internal
fixation
Femoral Neck
Fractures
Active,
NR
222
Hip Arthroplasty
Active,
NR
50
Adt Sep-11 Mar-12 Northern
Sen
Orthopaedic
Division,
Denmark;
Medichanical
Engineering
Adt 39783 Feb-12 Lovisenberg
Diakonale
Hospital; Helse
Sor-Ost; Biomet,
Inc.; Ullevaal
University
Hospital
Adt Oct-02 Dec-11 Ullevaal
Sen
University
Hospital;
Norwegian
Foundation for
Health and
Rehabilitation;
The Research
Council of
Norway
Adt Oct-01 Dec-11 Ottawa Hospital
Sen
Research
Institute; Stryker
Nordic
New Tool of Subjective and
Objective Functional Evaluation
and the Quality of Life After
Arthroplastic Surgery of the Hip
and the Knee Assisted or Not by
Computer and Mini-invasive
Arthroplasty
RCT
NCT00894218
Clinical Evaluation on the Use of
the X-pander Device
NCT01443975
Procedure:
Arthroplasty
Wear Measurements of E-Poly in
an Uncemented THA With Either
32 or 36 mm Caput of Ceramics.
NCT00804388
Hemiarthroplasty or Internal
Fixation for Displaced Femoral
Neck Fractures - 5 Years Follow
up
RCT, efficacy study
NCT00764153
Hip Arthritis; Knee
Arthritis
Procedure: x-pander Osteoarthrosis; Total
Hip Arthroplasty
A Comparison of Two Type of
Procedure: BMD;
Stems in Revision Hip Arthroplasty Procedure: BMD
study
NCT00253838
187
Metal Ion Release From an FDA- Procedure: Total Hip Non-inflammatory
Approved Metal-on-Metal Total Hip Replacement
Degenerative Joint
Replacement Implant
Disease
RCT
NCT00962351
Active,
NR
120
Evaluation of Functional
Procedure: THA
Osteoarthritis, Hip
Comp 104
Rehabilitation in Patients
Physiotherapy;
Undergoing Physiotherapy After
Procedure: No
physiotherapy after
RCT, efficacy study
THA
NCT01491048
A Randomised Multi-centre Study Procedure: DePuy Osteoarthritis(Primar Term
61
to Compare the Short-term
MI System;
y)
Outcomes of Minimally Invasive
Procedure:
and Conventional Surgery in
Conventional
surgical technique
study
NCT00208416
Acupuncture for Pain Management Procedure:
Pain; Postoperative Wdrwn 90
After Hip or Knee Arthroplasty
Acupuncture;
Complications
RCT, efficacy study
Procedure: Sham
NCT00455182
Acupuncture;
Procedure: Standard
medical care
Total Hip Arthroplasty Compared Procedure: Internal Femoral Neck
Active, 100
to Internal Fixation for Displaced fixation; Procedure: Fracture
NR
Intracapsular Fractures of the
Total hip arthroplasty
Femoral Neck
RCT, efficacy study
NCT01344772
A Clinical Evaluation of Metal Ion Procedure: metal on Osteoarthritis;
Term
86
Release From Metal-on-Metal
metal hip
Avascular Necrosis;
Cementless Total Hip Arthroplasty arthroplasty
Traumatic Arthritis;
study
NCT00757354
188
Adt Oct-03 Dec-11 Anderson
Sen
Orthopaedic
Research
Institute;
University of
Western Ontario,
Canada; DePuy
Orthopaedics
Adt Jul-09 Oct-11 Hospital de
Sen
Clinicas de Porto
Alegre
Adt Oct-05 Sep-11 DePuy
Sen
International
Adt Mar-07 Jun-11 HealthEast Care http://ClinicalTrials.gov/show/NCT00455182
Sen
System (US)
Adt Feb-90 Jun-11 Danderyd
Sen
Hospital
Adt Mar-06 Jun-11 Biomet, Inc.;
Sen
Biomet U.K. Ltd.
Local Anesthetic Infiltration and
Infusion for Pain Control After Hip
Replacement
RCT, efficacy study
NCT01409278
Minimally Invasive Surgery of the
Hip Versus Standard Approach
RCT
NCT00261040
Effect of Cemented Stem Design
on Periprosthetic Bone Mass
Following Primary Total Hip
Arthroplasty
NCT00293605
Pelvic Alignment Level (PAL™)
Instrument Evaluation
RCT
NCT01312428
Procedure:
Osteoarthritis
Ropivacaine
infiltration and saline
infusion.; Procedure:
Ropivacaine
infiltration and
infusion.; Procedure:
Normal Saline
Procedure: minimally Hip Arthroplasty;
invasive total hip
Osteoarthritis
arthroplasty;
Procedure: Standard
Procedure: Total Hip Osteoarthritis
Replacement
Comp
105
Adt Aug-09 Jun-11 Saint Francis
Sen
Care
Comp
40
Comp
120
Adt Jun-03 May-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00261040
Sen
Research
Institute;
Zimmer, Inc.
Adt Jan-04 Apr-11 Sheffield
Sen
Teaching
Hospitals NHS
Foundation Trust
Procedure: Pelvic
Arthroplasty,
Alignment Level
Replacement, Hip
(PAL) Instrument;
Procedure: Total Hip
Replacement
Procedure: Mini
Osteoarthritis
Incision Approach;
Procedure: 2 Incision
Approach
Term
60
Adt Feb-11 Mar-11 Stryker
Sen
Orthopaedics
Active,
NR
90
Adt Jun-06 Dec-10 Rush University http://ClinicalTrials.gov/show/NCT00594893
Sen
Medical Center;
Zimmer, Inc.
Femoral Neck
Fractures
Active,
NR
230
Sen Sep-04 Dec-10 Ullevaal
University
Hospital; Asker
& Baerum
Hospital
Femoral Neck
Fractures
Wdrwn 100
Sen Oct-04 Dec-10 Northern
Orthopaedic
Division,
Denmark
Study Comparing Mini-Incision
Versus 2-Incision Approach for
RCT, efficacy study
NCT00594893
A Prospective Randomized Trial of Procedure:
Uncemented Versus Cemented
Uncemented primary
Hemiarthroplasty for Displaced
bipolar
hemiarthroplasty of
RCT, efficacy study
the hip; Procedure:
NCT00491673
Cemented primary
bipolar
hemiarthroplasty of
the hip
Bipolar Versus Unipolar
Procedure: Unipolar
Hemiarthroplasty for Patients With Hemiarthroplasty of
a Hip Fracture
the hip joint;
RCT, efficacy study
Procedure: bipolar
NCT00317837
hemiarthroplasty
189
Study on Cemented Versus Noncemented Hemiarthroplasty in
Elderly With Hip Fractures
NCT00800124
Procedure:
Hip Fracture
cemented Landos
prosthesis vs.
uncemented Landos
prosthesis
Active,
NR
300
Prospective randomised study
comparing the Furlong
uncemented total hip replacement
with the Birmingham resurfacing
prosthesis
RCT, efficacy study
ISRCTN00324631
Can the Femoral Nerve Block be
Improved by Ultrasound
Guidance?
NCT00696150
Furlong uncemented Hip replacement
total hip
replacement;
Birmingham
resurfacing
prosthesis
Comp
100
Procedure:
determination of
method with highest
efficacy (ultrasound
or nerve stimulator);
Procedure: nerve
stimulator;
Procedure: loss of
resistance
Femoral Versus Psoas Continuous Procedure: Femoral
Peripheral Nerve Blocks Following Nerve Block vs.
Hip Arthroplasty
Psoas Compartment
Nerve Block
NCT00967980
The Warwick Arthroplasty Trial
Total Hip
RCT, efficacy study
Arthroplasty; Hip
ISRCTN33354155
Resurfacing
Arthroplasty
Pain; hip
arthroplasty
Not yet 269
Rec
Sen Jun-05 Oct-10 Sykehuset
Innlandet HF;
Rikshospitalet
University
Hospital;
Sykehuset
Buskerud HF
N/K Sep-00 Sep-10 Department of
Health (UK)
Adt
Sen
Jul-08 Aug-10 NHS Greater
Glasgow and
Clyde; Golden
Jubilee National
Hospital
Hip Arthroplasty; Hip Comp
Pain
50
Adt Sep-09 Aug-10 University of
Sen
California, San
Diego
hip joint
Comp
172
Rec
100
Adt Jun-07 May-10 University
Hospitals
Coventry and
Warwickshire
NHS Trust (UK)
Adt Jun-07 Apr-10 Tennessee
Sen
Orthopedic
Alliance
Comp
80
Restoration of Leg Length, Offset, Procedure: Total hip Arthritis
and Center of Rotation in Total Hip replacement
Replacement
NCT00738803
Preheating of Femur Component Procedure: Total hip Osteoarthritis, Hip
in Hybrid Total Hip Arthroplasty
replacement
(Preheating of femur
NCT00319085
stem)
190
Sen May-06 Apr-10 Northern
Orthopaedic
Division,
Denmark
Computer-assisted Minimally
Invasive total hip Surgery (MIS): a
randomised controlled trial into the
effectiveness compared to
traditional total hip arthroplasty
RCT
ISRCTN52538512
Other
Genetics Informatics Trial (GIFT)
of Warfarin to Prevent DVT
study
NCT01006733
Computer-assisted
minimally invasive
total hip surgery;
total hip arthroplasty
Total hip
replacement due to
primary or
secondary
osteoarthritis
Other:
Thromboembolism;
Arthroplasty, Knee;
Pharmacogenetic
Arthroplasty, Hip
Warfarin Initiation;
Other: Clinical
Warfarin Initiation
(nonpharmacogenetic);
Other:
Pharmacogenetic
Other: Clinical
Warfarin Initiation
(nonpharmacogenetic)
Epsilon Aminocaproic Acid (EACA) Other: EACA; Other: Degenerative Joint
for the Reduction of Blood Loss in Placebo arm
Disease;
Total Hip Arthroplasty (THA)
Osteoarthritis
RCT, safety study
NCT01391182
Cell Saver Use in Bilateral Total
Other: Cell Saver
One-stage Bilateral
Hip Arthroplasty (THA)
Total Hip
NCT01468129
Replacement
Total Hip Arthroplasty (THA): Early Other: Early loading; Primary Total Hip
Load Versus Load Late
Other: Late loading Arthroplasty
NCT01495546
Liberal Versus Restrictive
Other: Red blood cell Arthroplasty, Hip
Transfusion During Symptomatic transfusion; Drug:
Moderate Anemia After Hip
Voluven
Arthroplasty
RCT, efficacy study
NCT01452581
Comp
Rec
Rec
132
Adt Jan-07 Jan-10 University
Medical Center trials.com/ISRCTN52538512
Groningen (The
Netherlands)
1600 Adt Mar-11 Aug-15 Washington
Sen
University
School of
Medicine;
Intermountain
Health Care,
Inc.; University
of Utah; Hospital
for Special
Surgery, New
York; National
Heart, Lung, and
Blood Institute
(NHLBI)
120 Adt Jul-11 Jul-13 Mayo Clinic
Sen
Rec
N/K
Rec
40
Rec
70
191
Adt Nov-11 Dec-12 Rothman
Sen
Institute
Orthopaedics
Adt Dec-11 Dec-12 University of Sao http://ClinicalTrials.gov/show/NCT01495546
Paulo
Adt Oct-11 Dec-12 Rigshospitalet,
Sen
Denmark
POMX (Post Operative Morbidity):
Randomized controlled trial of
chewing gum to reduce
postoperative morbidity in elective
orthopaedic surgery
RCT, efficacy study
ISRCTN20301599
Group Exercise After Hip
Replacement Surgery
RCT, efficacy study
NCT01253798
Preoperative Resistance Training
in Patients Scheduled for Total Hip
Arthroplasty
RCT
NCT01164111
Optimising patient function
following elective Total Hip
Replacement (THR) surgery
RCT
ISRCTN13019951
Rehabilitation After Total Hip
Arthroplasty - the Effect of Taskoriented Exercises
RCT, efficacy study
NCT00808483
Prospective Study Deltamotion DAA THA Study
NCT01474031
Preoperative Exercise in Patients
Undergoing Total Hip or Knee
Replacement
RCT
NCT01003756
Chewing gum
Elective orthopaedic
hip and knee
arthroplasty
procedures
Active
106
(UK)
Other: Group training Hip Osteoarthritis;
Exercise;
Hydrotherapy
Rec
54
Other: Preoperative Osteoarthritis; Hip
resistance training
Arthroplasty
Rec
80
Training exercises in Total hip
the pre-assessment replacement
clinic & postoperatively and given
information sheets +
home visit by
physiotherapist;
Routine in- & outpatient physiotherapy
+ standard
information leaflets
Other: Task-oriented Total Hip
exercises
Arthroplasty; Taskoriented Exercises
Comp
50
Child Nov-10 Jul-12 Norwegian
Adt
University of
Sen
Science and
Technology
Adt Oct-10 Jun-12 University of
Sen
Southern
Denmark;
University of
Copenhagen
N/K Mar-10 Mar-12 Bangor
University (UK)
Active,
NR
72
Sen
Oslo
Rec
40
Comp
165
Adt Oct-11 Aug-11 Universitaire
Sen
Ziekenhuizen
Leuven; DePuy
International
Adt Nov-09 Aug-11 University of
Sen
Southern
Denmark;
Odense
University
Hospital
Other: biomechanics Arthroplasty,
Replacement, Hip;
Biomechanics
Other: Preoperative Osteoarthritis
neuromuscular
exercise
192
Time to Total Hip Replacement
After Supervised Exercise and
Patient Education
RCT, efficacy study
NCT01338532
Transfusion Requirements in
Orthopedic Surgery (PHASE 2)
NCT00726349
Wound closure following hip
arthroplasty
RCT, efficacy study
ISRCTN70685656
Cost-Effectiveness of Web-Based
Follow Ups
NCT01079572
Other: A 12 week
Hip Osteoarthritis
supervised exercise
program and patient
education; Other:
Patient education
Other: No
Total Hip or Knee
intervention
Arthroplasty
Active,
NR
109
Adt Mar-05 May-11 Oslo University
Sen
Hospital
Comp
305
Standard absorbent
dressing;
DERMABOND®
tissue adhesive
Other: in-person;
Other: web-based
Comp
219
Sen
hospitalier de
l'Université de
Montréal
Adt Apr-10 Apr-11 NHS Greater
Sen
Glasgow and
Clyde (UK)
Elective Total Hip
Replacemen
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Effects of a Late Phase Exercise Other: home based
Program Following Total Hip
exercise and
Arthroplasty
education program
NCT00896259
Total Hip
Arthroplasty
Prophylactic Anticoagulation for
Other: prophylactic
Preventing Deep Vein Thrombosis anticoagulation
After Total Hip Arthroplasty
study
NCT01446887
Deep Vein
Thrombosis
Restoration® Anatomic Dual
Mobility (ADM) X3® Acetabular
System
NCT01420237
Rejuvenate Modular Outcomes
Study
NCT01257568
Rec
1000 Child Feb-10 Mar-11 University of
Adt
Western Ontario,
Sen
Canada; The
Physicians'
Services
Incorporated
Foundation
Comp 60
Adt Mar-09 Feb-11 Capital District http://ClinicalTrials.gov/show/NCT00896259
Sen
Health Authority,
Canada;
Canadian
Orthopaedic
Foundation
Comp
Adt Jan-07 Feb-11 JIANG Qing
Sen
Arthroplasty,
Replacement, Hip
Rec
350
Adt Jun-11 Aug-24 Stryker
Sen
Orthopaedics
Arthroplasty,
Replacement, Hip
Rec
240
Adt Nov-10 Nov-22 Stryker
Sen
Orthopaedics
193
A Clinical Investigation of
ArComXL® Polyethylene in Total
Hip Replacement
NCT00698152
Hospital for Special Surgery Hip
Arthroplasty Cohort
NCT00454506
Osteoarthritis;
Active,
Avascular Necrosis;
NR
LFIT™ Anatomic CoCr Femoral
Heads With X3® Polyethylene
Insert Study
NCT00510458
Short-Term Clinical Outcome of
Total Hip Arthroplasty Using
Larger Diameter of 4th Generation
Ceramic Bearing
NCT01103882
Vitamin D and Functional
Outcomes After Total Hip
Arthroplasty (THA)
NCT01397383
Length of Stay and Complications
in High-risk Patients Receiving
Fast-track Total Hip (THA) or
Knee- Alloplasty (TKA)
NCT01515670
Alberta Hip Improvement Project
study
NCT00293774
Determination of Metal Ion Serum
Levels and Cytokines in Total Hip
Replacement
NCT01394744
Arthroplasty,
Replacement, Hip
OR Arthroplasty
Hip Arthroplasty
149 Child Jan-06 Apr-18 Biomet
Adt
Orthopedics,
Sen
LLC
Rec
3000 Adt Apr-07 Apr-17 Hospital for
Sen
Special Surgery,
New York;
Agency for
Healthcare
Research and
Quality (AHRQ)
Active, 95
Adt Apr-07 Dec-15 Stryker
NR
Sen
Orthopaedics
Arthropathy of Hip
Rec
277
Adt May-10 May-15 Biomet, Inc.
Sen
Vitamin D Deficiency
Rec
200
Adt Mar-10 Mar-15 Hospital for
Sen
Special Surgery,
New York
Arthroplasty
Complications;
Preoperative Comorbidity;
Postoperative
Morbidity
Arthroplasty,
Replacement, Hip
Rec
3000 Adt Feb-10 Jan-15 Rigshospitalet,
0
Sen
Denmark
Rec
1000 Adt
Total Hip
Replacement
Rec
30
194
Jun-04 Sep-14 Alberta Bone
and Joint Health
Institute
Adt Aug-11 Jan-14 University of
Sen
Munich
(German)
Evaluation of Weight Bearing After
Total Hip and Knee Replacement
NCT01135160
150 mg/q.d. in Patients With
Moderate Renal Impairment After
Hip or Knee Replacement Surgery
NCT00847301
Postoperative Anemia and
Functional Outcomes After Fasttrack Primary Hip Arthroplasty
NCT01514006
Arthroplasty,
Replacement, Hip;
Total Knee
Arthroplasty
Arthroplasty,
Replacement;
Thromboembolism
Not yet 200 Child Aug-12 Dec-13 Kantonsspital
Rec
Adt
Münsterlingen
Sen
Arthroplasty, Hip
Replacement;
Anemia
Not yet 125
Rec
Metal Ions in Ceramic on Metal
NCT01437124
Osteoarthritis;
Not yet
Avascular Necrosis;
Rec
Developmental
Dysplasia of the Hip
Coxarthrosis
Active,
NR
83
Knee Replacement;
Hip Replacement;
Hyperglycemia
Active,
NR
200
Rec
60
Migration Pattern of C-stem AMT
Versus Exeter in Total Hip
Arthroplasty
NCT00722982
Perioperative Hyperglycaemia in
Replacement
NCT01021826
Functional Recovery After Partial
Hip Arthroplasty: Anterior or
Posterolateral Approach?
NCT01520961
Hip Arthroplasty;
Femoral Neck
Fractures
Rec
500
70
195
Adt Apr-09 Apr-13 Boehringer
Sen
Ingelheim
Pharmaceuticals
Adt Jan-12 Feb-13 Rigshospitalet,
Sen
Denmark;
University
Hospital,
Gentofte,
Copenhagen;
Vejle Hospital
Adt Oct-11 Dec-12 Hussain Kazi
Sen
Adt
Sen
Jul-08
Jul-12 Ullevaal
University
Hospital;
Ringerike
hospital HF,
HÃ¸nefoss
Norway;
Ortomedic AS,
Lysaker Norway;
Helse Sor-Ost
Adt Dec-09 Jul-12 Coxa, Hospital http://ClinicalTrials.gov/show/NCT01021826
Sen
for Joint
Replacement;
University of
Tampere
Adt Dec-11 May-12 Hôpital
Sen
Ambroise Paré
Serum Metal Ion Concentrations
Following Primary Hip Arthroplasty
Cross-sectional, case-only
study
NCT00714610
Stem Cells Predicting Orthopedic
Outcomes
Prospective study
NCT01366911
Preoperative Pain, Function, and
Activity for Total Hip and Knee
Arthroplasty Patients
NCT01248039
Thigh Swelling, Hip-muscle
Strength, and Functional
Performance Following Total Hip
Arthroplasty
NCT01246674
Surgical Field Bacterial
Contamination in Primary Total Hip
(THA) and Knee (TKA)
Arthroplasty
NCT01493375
Tissue Culture Versus Swab
Culture in Prosthetic Joint
Infections
NCT01482533
Cognition in Postoperative Total
Hip Arthroplasty and Total Hip
Resurfacing Patients
NCT01079468
Medium and Long Term Outcome
of Total Hip Arthroplasty Using
Accolade TMZF Femoral Stem
Case-only study
NCT00951145
Healthy
Active,
NR
110
Adt Jun-07 May-12 University of
Sen
Utah
Invite
50
Child Apr-11 Apr-12 University of
Adt
Nebraska
Sen
Arthroplasty
Rec
100
Osteoarthrosis
Patients With Total
Hip Arthroplasty
Rec
30
Adt Jan-11 Jan-12 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Sen
University
Hospital;
Lundbeck
Foundation
Comp
60
Adt Jun-10 Dec-11 Northern
Sen
Orthopaedic
Division,
Denmark
Hip Arthroplasty
Prosthetic Infections
Revision Total Hip
Not yet N/K
Arthroplasty;
Rec
Revision Total Knee
Arthroplasty
Adt
Sen
Nov-11 Rothman
Institute
Orthopaedics
Cognition
Comp
100
Adt Jan-10 Nov-11 Rothman
Sen
Institute
Orthopaedics
Hip
Active,
NR
N/K Child
Adt
Sen
Nov-11 Rothman
Institute
Orthopaedics;
Stryker
Orthopaedics
196
N/K
N/K
Postoperative Sleep Disturbances
Role in Cognitive Test Results
After Fast-track Hip and Knee
Arthroplasty
Prospective study
NCT01383369
Pradaxa (Dabigatran Etexilate 220
mg/q.d. in the General Population
After Hip or Knee Replacement
Surgery
NCT00846807
Outcomes Following Anterior
Approach to Total Hip Arthroplasty
NCT01353885
Impact of Spontaneous Breathing
on Ventilation Distribution in
Obese Patients
NCT01382927
Dual Energy X-rayY
Absorptiometry (DXA) Comparison
Hip Resurfacing Versus Total Hip
Arthroplasty (THA)
NCT01359527
Femoral Remodeling Following
Total Hip Arthroplasty With Omni
Apex Modular™, OMNI Apex
ARC™ Stem, and Omni Apex
"Conical Stem" Compared to
Competitive Designs
NCT01359540
Effect of Rivaroxaban on
Coagulation Parameters- an ex
Vivo Study
NCT00986635
Postoperative
Cognitive Abilities
Comp
20
Adt Feb-11 Aug-11 Rigshospitalet,
Sen
Denmark
Arthroplasty,
Replacement;
Thromboembolism
Comp 5476 Adt Feb-09 Jul-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Osteoarthritis, Hip
Not yet 700
Rec
Jul-11 Jul-11 McMaster
University;
DePuy
Orthopaedics
Adt Apr-11 Jun-11 Dresden
Sen
University of
Technology
Adt
Sen
Obesity; Hip
Arthroplasty;
General Anesthesia;
Spinal Anesthesia;
Atelectasis
Total Hip
Replacement;
Osteoarthritis; Bone
Loss
Rec
16
Rec
25
Child Dec-08 May-11 Spokane Joint
Adt
Replacement
Sen
Center
Hip
Rec
75
Child Nov-09 May-11 Spokane Joint
Adt
Replacement
Sen
Center
100
Adt Sep-09 Apr-11 Johann
Sen
Wolfgang
Goethe
University
Hospitals
Hip or knee
Comp
replacement surgery
197
Effect of Dabigatran on
Coagulation parameters-an ex
Vivo Study
NCT01112202
Recovery at the Post Anaesthetic
Care Unit After Hip and Knee
Arthroplasty
NCT01178489
Why in Hospital - Factors
Determining Time to Discharge
Readiness After Arthroplasty
Surgery
NCT01047371
Cardiovascular Changes and
Changes in Tissue Oxygenation
During Early Postoperative
Mobilization in Total Hip
Arthroplasty (THA) Patients
NCT01089946
Physical Functioning Following
NCT00651430
Study to evaluate the safety and
efficacy of pradaxar for the
prevention of venous thromboembolism in the Mexican
population undergoing elective
total hip or knee replacement
surgery
NCT00967447
Hip or knee
Comp
replacement surgery
70
PACU Stay After
THA or TKA Under
Spinal Anaesthesia
Comp
170
Arthroplasty, Hip;
Arthroplasty, Knee
Comp
Arthroplasty
Adt Apr-10 Apr-11 Johann
Sen
Wolfgang
Goethe
University
Hospitals
Adt Aug-10 Jan-11 Hvidovre
Sen
University
Hospital
200
Adt Jan-10 Aug-10 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Comp
26
Adt Mar-10 Jun-10 Rigshospitalet,
Sen
Denmark
Osteoarthrosis,
Comp
Balance Control,
Voluntary Movement
Control
Thromboembolism;
Term
Arthroplasty,
Replacement, Hip
30
Adt Mar-08 May-10 Soroka
Sen
University
Medical Center
N/K
Adt Feb-09 Mar-10 Boehringer
Sen
Ingelheim
Pharmaceuticals
198
A8D: OTHER
Title
CT ID
Behavioural
Supporting Decision Making for
Musculoskeletal PreferenceSensitive Care
RCT
NCT01345123
EMPART - Exercise and Manual
Physiotherapy Arthritis Research
Trial
Phase III: RCT
NCT00709566
Hip Osteoarthritis: Effects of
Exercise Programs on Pain and
Disability
RCT, efficacy study
NCT00682617
Device
10 Year Clinical Evaluation of
Primoris Hip Component
NCT01326832
Tritanium® Primary Acetabular
Shell Study
NCT01063751
Interventions
Conditions
Behavioral: Provision Knee Pain Chronic;
of condition specific Arthritis (Hip);
DVD and Pamphlet Arthritis (Knee);
to support Shared
Back Pain
Decision Making;
Behavioral:
Telephonic outreach
and support by
Health Coach;
Behavioral: No
condition specific
telephonic outreach
Behavioral: Exercise Hip Osteoarthritis
therapy; Behavioral:
Combined exercise
and manual therapy
Recruit
n
Age Start
(Grp) Date
End Sponsors
Date
URL
Active, 18000 Adt Feb-11 Mar-12 Health Dialog;
NR
Sen
Foundation for
Informed
Medical Decision
Making;
University of
Massachusetts,
Boston
Active,
NR
150
Adt Apr-08 Dec-10 Royal College of http://ClinicalTrials.gov/show/NCT00709566
Sen
Surgeons,
Ireland
Behavioral:
Hip Osteoarthritis
Structured exercise
program; Behavioral:
Waitlist, delayed
intervention
Rec
30
Adt Aug-06 Jul-10 Oregon Health
Sen
and Science
University
Device: Primoris
Rec
400
Adt Sep-11 Dec-24 Biomet, Inc.;
Biomet Denmark
A/S
Rec
240
Adt
Sen
Coxarthrosis
Device: Tritanium® Osteoarthritis;
Primary Acetabular Traumatic Arthritis;
Shell; Device:
Avascular Necrosis
Tritanium® Primary
Acetabular Shell with
Periapatite
199
Jul-11
Jul-24 Stryker
Orthopaedics
The Metaphyseal Hip Prosthesis Total Hip
NCT01501955
A Clinical Investigation of the C2aTaper™ Acetabular System
NCT00578851
Device: Metaphyseal
Hip Prosthesis;
Device: Stanmore
hip prosthesis
Device: C2a Taper™ Acetabular
System
Hip
Not yet
Rec
50
Adt Mar-12 Mar-23 Biomet, Inc.
Sen
Osteoarthritis;
Active,
Avascular Necrosis;
NR
Congenital Hip
Dysplasia; Traumatic
Arthritis
Trilogy AB Acetabular Hip System Device: Trilogy AB Osteoarthritis;
Rec
Post Approval Study
Acetabular Ceramic Avascular Necrosis;
Hip System
Congenital Hip
Dysplasia; Traumatic
study
Arthritis
NCT00715026
ReCap Total Hip Resurfacing
Device: ReCap Total Arthritis
Rec
Prospective Data Collection
Hip Resurfacing
NCT00758472
A Safety and Efficacy Study of the Device: Birmingham Arthritis
Rec
Birmingham Hip Resurfacing
Hip Resurfacing
System
System
NCT00611585
Post-PMA Approval Study: 10
Device: Cormet Hip Osteoarthritis;
Invite
Year Follow-Up IDE Subjects
Resurfacing System Avascular Necrosis;
NCT00721994
A Prospective Clinical Study On A Device: ReCap Total Arthritis; Avascular
Rec
Total Hip Resurfacing System
Hip Resurfacing
Necrosis
System
NCT00604734
A Prospective Clinical Study On A Device: ReCap Total Arthritis; Avascular
Active,
Total Hip Resurfacing System
Hip Resurfacing
Necrosis
NR
System
NCT00603395
34
Adt Apr-06 Apr-22 Biomet
Sen
Orthopedics,
LLC
250
Adt Apr-09 Apr-21 Zimmer, Inc.
Sen
500
Adt Mar-05 Mar-20 Biomet, Inc.;
Sen
Biomet U.K. Ltd.
400
Adt Sep-06 Sep-18 Smith &
Sen
Nephew, Inc.
450 Child May-08 May-18 Corin
Adt
Sen
500 Child Oct-04 Oct-17 Biomet, Inc.
Adt
Sen
300 Child Sep-04 Sep-17 Biomet, Inc.;
Adt
Knowledge
Sen
Center for
Orthopedic
Surgery, St.
Anna Hospital,
Geldrop,
Netherlands
200
Cementless Alumina-Alumina
Device:
Total Hip and Hybrid
Alumina/Alumina;
Device: Standard
study
NCT00764530
Evaluation of the Trabecular
Device: Zimmer
Metal™ Revision Hip Cup Using Trabecular Metal
Bone Mineral Density (DEXA)
Revision Cup;
Device: Zimmer
NCT01183260
Modular Cup
A Migration and Bone Density
Device: Hi-Fatigue
Study Comparing Hi-Fatigue Bone Bone Cement;
Cement and Palacos Bone
Device: Palacos
Cement
Bone Cement
study
NCT01289834
Local Gentamicin Application to
Device: CollagenReduce Postoperative Infection
gentamicin sponge
Rate
NCT01287780
Post PMA-Approval Study: New
Device: Cormet Hip
Enrollment Post PMA-Approval
Resurfacing
Study Post-approval Study Group
(New Enrollment)
study
NCT00722007
Study of Low-Magnitude, HighDevice: LowFrequency Vibration Treatment on magnitude high Osteoporotic Hip Fracture Healing frequency vibration
Phase II/III: RCT, safety/efficacy treatment
study
NCT01293721
Comparison of Conventional and Device: Large
Large Diameter Femoral Heads for Diameter Femoral
the Prevention of Hip Dislocation Head
RCT, efficacy study
NCT00175500
Avascular Necrosis
342
Adt Nov-03 Nov-14 Encore Medical, http://ClinicalTrials.gov/show/NCT00764530
Sen
L.P.
Revision, Joint
Rec
20
Adt Aug-10 Aug-14 The Cleveland
Sen
Clinic; Zimmer,
Inc.
Hip Arthritis
Rec
50
Sen Aug-10 Aug-13 University of
Aarhus; Aarhus
University
Hospital;
Zimmer, Inc.
Surgical Wound
Infection
Rec
800 Child Jan-11 Dec-12 Oslo University
Adt
Hospital
Sen
Osteoarthritis;
Avascular Necrosis;
Rec
160 Child Apr-08 Dec-12 Corin
Adt
Sen
Hip Fracture
Rec
40
Adt May-07 Dec-12 Chinese
Sen
University of
Hong Kong
Fonly
Active,
NR
400
Sen
British Columbia
Hip Dislocation
201
Balloon Assisted Hip Arthroscopy Clinical Evaluation of a New Tool
for Hip Arthroscopy
NCT01429805
Multi-Center Comparative Trial of
the ASR™-XL Acetabular Cup
System vs. the Pinnacle™ Metalon- Metal Total Hip System
study
NCT00561600
A Randomised Study to Compare
Metal Ion Release and Long-term
Performance of the Pinnacle™
Cup With a Ceramic-on-Metal or a
Metal-on-Metal Bearing
study
NCT00873444
Study Performance of The Plexur
P™ Bone Void Filler Device in
Patients Undergoing Iliac Crest
Harvesting Procedures
NCT00837473
Clinical Study on BiHapro Total
Hip System With Different Surface
Coatings
NCT00755001
Bone Remodeling Around HAcoated Acetabular Cups.
NCT00159497
Device: HipJack
Balloon Spacer
Hip Arthroscopy
Rec
40
Adt Sep-11 Feb-12 Pivot Medical
Sen
Inc.
Device: ASR™-XL Osteoporosis;
Modular Acetabular Arthritis; Trauma
Cup System; Device:
Pinnacle™
acetabular shell
Comp
300
Adt Aug-06 Jan-12 DePuy
Sen
Orthopaedics
Device: Pinnacle™
Acetabular System;
Device: Pinnacle™
Acetabular System
Term
190
Adt
Sen
Active,
NR
15
Adt Jan-09 Oct-11 Osteotech, Inc
Sen
Term
40
Child May-07 May-11 Biomet, Inc.;
Adt
Biomet Spain
Sen
Orthopaedics
S.L.
Comp
100
Adt Oct-98 Jan-11 Northern
Sen
Orthopaedic
Division,
Denmark
Collagen Disorders;
Avascular Necrosis;
Congenital Hip
Dysplasia; Slipped
Capital Femoral
Epiphysis
Device: Plexur-P
Iliac Crest
used as a Bone Void Harvesting
Filler in Iliac Crest
Procedure-Bone
Harvesting
Void Filler;
Procedures
Device: BiHapro hip Osteoarthritis
stem with PPS
Ti+Plasma HA;
Device: BiHapro hip
stem with PPS
Ti+BoneMaster HA
Device: porous
Coxarthrosis
coated Trilogy®;
Device: Trilogy
Calcicoat®
202
Jul-06 Jan-12 DePuy
International
Metal on Metal Versus Metal on
Highly Crossed Linked
Polyethylene Sytem
study
NCT01422564
Device: Metal on
Metal Hip System;
Device: Highly Cross
Linked Polyethylene
cup System
Osteoarthritis;
Term
Avascular Necrosis;
Congenital
Dysplasia of the Hip;
Ankylosing
Spondylitis; Posttraumatic; Arthrosis;
Injury of Hip and
Thigh
Aortic Diseases;
Active,
Osteoarthritis, Hip
NR
41
Adt Jan-07 Dec-10 Capital District http://ClinicalTrials.gov/show/NCT01422564
Sen
Health Authority,
Canada;
University Health
Network,
Toronto
20
Adt Nov-09 May-10 Sykehuset i
Sen
Vestfold HF;
Oslo University
Hospital; Astra
Tech AB
Comp
150
Adt Feb-09 Jan-10 Hopital de
Sen
l'Enfant-Jesus
Rec
24
Child Aug-09 Aug-15 University of
Adt
Aarhus
Invite
342
Sen
Utah
Drug: Placebo; Drug: Degenerative Joint
Gapabentin
Disease of Hip and
Knee.
Rec
90
Drug: Zoledronic
Osteonecrosis
Acid; Drug: Placebo
Rec
120
Adt Mar-12 Dec-14 University of
Sen
Medicine and
Dentistry New
Jersey
Sen
Sydney; Novartis
Pro-inflammatory Cytokines in
Device: Sangvia
Blood From Orthopedic Surgery
blood sampling
Compared to Abdominal Aneurysm system
Repair
NCT00851149
Evaluation of Three Types of
Device: Dressing of Tape Blisters; Hip
Dressings After Hip Surgery
wound; Device:
Surgery
Dressing of wound;
NCT01469871
Device: Dressing of
wound
Postoperative Pain in Children
With Cerebral Palsy After Pelvic
and Femoral Osteotomies
Phase IV: RCT
NCT00964639
Influence of Naproxen on
Heterotropic Bone Formation
Following Hip Arthroscopy
RCT, efficacy study
NCT01539447
Effect of Gabapentin on
Orthopedic Pain
NCT01546857
Osteonecrosis of the Hip and
Bisphosphonate Treatment
NCT00781261
Drug: Ropivacaine;
Drug: Saline
Postoperative Pain;
Cerebral Palsy
Drug: Naproxen;
Drug: placebo
Hip Arthroscopy
203
Autologous Chondrocyte Intraarticular Implantation in Patients
With Severe Hip Osteoarthritis
NCT01500811
Efficacy of Zoledronic Acid in
Preventing Collapse of the
Osteonecrotic Femoral Head
study
NCT00939900
Evaluate the Effect of Bone
Marrow Derived Cd133+ Cells in
Patient With Osteonecrosis of
Femoral Head
NCT01198080
Bisphosphonates and Impaction
Grafting in Hip Revision
NCT00658268
Efficacy and safety of autologous
conditioned serum
(ACS/Orthokine®) compared with
Triamcinolone in the treatment of
symptomatic hip osteoarthritis.
ISRCTN16719506
Perioperative Pregabalin Use,
Rehabilitation, Pain Outcomes and
Anxiety Following Hip Surgery
Phase IV: RCT
NCT00762099
Transversalis Fascial Plane Nerve
Block in Iliac Crest Bone Graft
RCT, efficacy study
NCT01133730
Biological: cell
injection
Hip Osteoarthritis
Rec
6
Adt Mar-11 Jun-13 Royan Institute
Drug: zoledronic acid Avascular Necrosis
(aclasta)
of Femoral Head
Rec
104
Adt
Jul-09 Dec-12 Seoul National
University
Bundang
Hospital;
Novartis Korea
Ltd.
Adt Aug-09 May-12 Royan Institute
Biological: CD133+
cells
Osteonecrosis
Rec
10
Drug: Clodronate;
Drug: Placebo
Aseptic Loosening of
the Hip Prosthesis
Rec
32
Adt Mar-08 Mar-12 Region Skane
Sen
ACS / Orhtokin®
injection;
Tramcinolone
injection
hip
Comp
130
Adt Mar-10 Dec-11 Orthogen AG
Sen
(Germany)
Drug: Pregabalin;
Drug: Placebo
Anxiety
Rec
184
Adt May-09 Dec-11 Sunnybrook
Sen
Health Sciences
Centre; Pfizer
Drug: Active
treatment; Drug:
Placebo Arm
Upper Limb Surgery; Not yet
Iliac Crest Bone
Rec
Harvest
56
Adt Aug-10 Nov-11 University Health http://ClinicalTrials.gov/show/NCT01133730
Sen
Network,
Toronto
204
Treatment of early stage
osteonecrosis of the femoral head
with implantation of autologous
bone marrow-derived and cultured
mesenchymal stem cells
RCT
ISRCTN18167626
Bone marrowOsteonecrosis of the Comp
derived
femoral head at
mesenchymal stem early stage
cell; utologous bone
marrow mononuclear
cells
100
Adt Mar-04 Sep-11 Dalian University http://www.controlledZhongshan
Hospital (China)
Pain Control
study
NCT01041313
Antiemetic Prophylaxis for
Postdischarge Nausea and
Vomiting After Hip Arthroscopy
NCT00878228
Efficacy of Zoledronic Acid in
Enhancement of Early Stability of
Cementless Primary Hip
Prosthesis
NCT01218035
Mesenchymal Stem Cell
Transplantation in Osteoarthritis of
Hip Joint
NCT01499056
Steroid versus hyaluronic acid
injections for hip arthritis
RCT
ISRCTN04950164
Drug: Memantine;
Drug: Placebo
Rec
120
Sen
Washington;
Forest
Laboratories
Drug: Ondansetron; Nausea and
Drug: Placebo
Vomiting,
Postoperative
Active,
NR
76
Adt
Drug: zoledronic acid Hip Osteoarthritis
Comp
49
Biological: stem cell Hip Osteoarthritis
injection
Comp
6
Adt May-07 Jun-11 Turku University http://ClinicalTrials.gov/show/NCT01218035
Sen
Hospital;
Academy of
FFinland;
only
Novartis; Stryker
Nordic
Adt Jun-10 Mar-11 Royan Institute http://ClinicalTrials.gov/show/NCT01499056
Kenalog®
Hip osteoarthritis
(triamcinolone)
intraarticular
injection; Hyaluronic
acid intraarticular
injection
Comp
Pain, Post-operative;
THR; TKR; lumbar
spinal fusion
Apr-09 Aug-11 Hospital for
Special Surgery,
New York
110 Child Jul-09 Dec-10 Dorset County http://www.controlledAdt
Hospital NHS
Sen
Foundation Trust
(UK)
205
Modulation of the Surgical
Inflammatory Response by
Etoricoxib
Phase II: RCT,
study
NCT00746720
Drug: Etoricoxib 60 Pain; Osteoarthritis,
mg; Drug: Placebo Hip; Analgesia
for Etoricoxib 60 mg;
Drug: Etoricoxib 60
mg; Drug: Placebo
for Etoricoxib 60 mg
Postoperative Analgesia With
Drug: Ropivacaine;
Local Infiltration After
Drug: Placebo
Periacetabular Osteotomy
study
NCT00815503
Effect of Local Administration of
Drug: morphine
Morphine for Analgesia After Iliac
Bone Graft Harvest
Phase IV: RCT
NCT01037335
Procedure
Pivotal, Multicentre, Randomised, Procedure: Core
Double-blind Controlled Study to decompression
Evaluate the Efficacy and Safety of
Autologous Osteoblastic Cells
(PREOB®) Implantation in Early
Stage Non Traumatic
Osteonecrosis of the Femoral
Head
study
NCT01529008
Hip Impingement - Understanding Procedure: MRI,
Cartilage Damage
qCT, motion
analysis; Procedure:
assignment
MRI, qCT, motion
NCT01546493
analysis; Procedure:
MRI, qCT, motion
analysis
Term
52
Periacetabular
Osteotomy; Pain
Comp
70
Autogenous Bone
Grafts
Rec
60
Adt Apr-09 Mar-10 Outcomes
Sen
Research
Consortium; The
Cleveland Clinic;
Haydarpasa
Numune
Training and
Research
Hospital
Avascular Necrosis
of Femur Head
Rec
130
Adt Nov-11 Nov-16 Bone
Therapeutics
S.A
Femoroacetabular
Impingement
Rec
75
Adt Sep-10 Sep-15 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01546493
Sen
Research
Institute;
Canadian
Institutes of
Health Research
206
Sen
ErlangenNürnberg
Medical School;
HELIOS Kliniken
GmbH; Rush
University
Medical Center;
Merck
Adt Jan-09 Dec-10 Odense
Sen
University
Hospital
UK FASHIoN: Feasibility study of a Hip Arthroscopic
Femoroacetabular
Active
trial of Arthroscopic Surgery for Hip Surgery; Nonimpingement (FAI)
Impingement compared with Non- operative care
operative care
RCT
ISRCTN09754699
Efficacy and Patient Satisfaction Procedure: Postop Wound Healing;
Rec
With AQUACEL® Ag Surgical
Dressing; Procedure: TKA; THA
Dressing Compared to Standard Postop Dressing
Surgical Dressing
NCT01258270
Acetabular Labral Tear in
Procedure: labrum Developmental
Rec
Dysplastic Hips
Dysplasia of the Hip;
Labrum
NCT01345838
The Effect of Perthes' Disease on Procedure: MRI
Perthes' Disease
Susp
Hip Cartilage
study
NCT00958464
Movement Pattern in Patients With Procedure: Minimally Hip Dysplasia
Rec
Hip Dysplasia
invasive approach for
Periacetabular
NCT01344421
osteotomy
Dynamic Imaging of the Hip for
Procedure: Motion Femoroacetabular,
Active,
Pre-operative Planning
analysis; Procedure: Impingement
NR
Motion analysis
assignment
NCT00605969
Procedure: PCCP; Level of Pain
Rec
and Inflammation After MinimalProcedure: DHS;
invasive Osteosynthesis of the
Procedure:
Proximal Femur
Osteosynthesis with
RCT
nails
NCT01264172
Local Infiltration Analgesia for Hip Procedure: Infiltration Pain
Rec
Arthroscopy
of local anesthetic;
RCT, efficacy study
Procedure: Normal
NCT01454518
Saline Injection
60
Adt Mar-12 Sep-13 University
Hospitals
Coventry &
Warwickshire
(UK)
300
Adt Dec-10 Aug-13 OrthoCarolina
Sen
Research
Institute, Inc.;
ConvaTec Inc.
100 Child Feb-10 Jun-13 University of
Adt
Aarhus
Sen
20
Child Jan-08 Apr-13 University of
Adt
British Columbia
60
Adt Mar-11 Jan-13 Aarhus
University
Hospital
30
Adt May-07 Dec-12 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00605969
Research
Institute
90
Adt Dec-10 Dec-12 RWTH Aachen
Sen
University
36
Adt Oct-11 Sep-12 Saint Francis
Sen
Care
207
The Effect of a Pre- and
Postoperative Orthogeriatric
Service
RCT, efficacy study
NCT01009268
Procedure:
Orthogeriatric
intervention
Dementia; Delirium
Rec
Osteoarthritis; TKA;
Procedure: PeriRec
articular injection of THA
marcaine/epinephrin
e; Procedure: Periarticular injection of
marcaine alone
Retrospective Follow-up Study
Procedure: Follow-up Congenital Deformity Comp
After Periacetabular Osteotomy in
of Hip Joints
Adults
NCT01348178
Bone Repair Cell (BRC) Treatment Procedure: Core
Osteonecrosis
Active,
of Patients With Osteonecrosis of decompression
NR
the Femoral Head
study
NCT00505219
Lumbar Plexus Block for
Procedure: Lumbar Postoperative Pain
Active,
Postoperative Pain Control After Plexus Blockade;
NR
Hip Arthroscopy. A Randomized Procedure: Control
Controlled Trial
Phase IV: RCT
NCT01286805
Controlled Study of Stage 3
Procedure: core
Non Traumatic
Comp
Osteonecrosis Treatment by Bone decompression with Osteonecrosis of the
Marrow
autologous bone
Femoral Head (Hip)
marrow implantation;
NCT01544712
Procedure: core
decompression of
the femoral head
Local Analgesia in Knee- and
Procedure: Position Rheumatoid Arthritis; Rec
Hipatroplastic Surgery in Patients of catheter
Orthopedic Surgery;
With Rheumatic Disease: ExtraAnalgesia
vs. Intracapsulare Position of
Catheter
RCT, efficacy study
NCT01050738
Study Comparing Peri-articular
Injection of Bupivacaine With and
Without Epinephrine
RCT, efficacy study
NCT00737139
400 Child Sep-09 Sep-12 Ullevaal
Adt
University
Sen
Hospital; The
Research
Council of
Norway
240 Adt Sep-08 Sep-12 Rush University http://ClinicalTrials.gov/show/NCT00737139
Sen
Medical Center
401 Child Mar-10 Nov-11 University of
Adt
Aarhus
Sen
120
Adt Sep-07 Jun-11 Aastrom
Sen
Biosciences
82
Adt May-10 May-11 Hospital for
Special Surgery,
New York; New
York
Presbyterian
Hospital
Adt Aug-04 Sep-10 University
Sen
Hospital of Liege
50
72
208
Child Jan-10 Aug-10 Spenshult
Adt
Hospital
Sen
Other
Shared Decision Making in
Other: Shared
Patients With Osteoarthritis of the Decision Making
Hip and Knee
Intervention
RCT
NCT01492257
Galileo-Hip Whole Body Vibration
/Conventional Physiotherapy
/Coxarthrosis
NCT01279174
Do Hip Injections Improve ShortTerm Biomechanical Outcomes In
Patients With Hip Pain
NCT01390103
Exercise Therapy and Patient
Education for Individuals With Hip
Osteoarthritis. Long-term Followup.
RCT, efficacy study
NCT01063777
Conservative Treatment for Hip
Osteoarthritis
RCT, efficacy study
NCT01039337
Rec
120
Not yet
Rec
40
Rec
Other: A 12 week
Hip Osteoarthritis
exercise therapy
program and patient
education.; Other:
Patient education
Other: Hip School;
Other: Hip School
and Manual
Treatment; Other:
Minimal control
intervention
Other: Conventional Coxarthrosis
physiotherapy
Other: Assessment Hip Pain
following hip injection
A Clinical Investigation of the M2aMagnum™ Hip System
NCT00698347
Outcome in Hip Preservation
Patients
NCT01550263
Hip Osteoarthritis;
Knee Osteoarthritis
Osteoarthritis, Hip
California, San
Francisco;
Stanford
University;
Robert Wood
Johnson
Foundation
Adt Apr-11 Oct-12 University of
Sen
Cologne
30
Sen
Florida
Active,
NR
109
Adt Jan-09 Dec-11 Ullevaal
Sen
University
Hospital
Active,
NR
120
Adt Oct-08 Jun-11 Nordic Institute
Sen
of Chiropractic
and Clinical
Biomechanics
(Denmark)
Active,
Arthritis; Rheumatoid NR
Arthritis; Joint
Disease; Bone
Disease
Hip Pain
Invite
Adt
Sen
Jul-11
249 Child Nov-04 Nov-18 Biomet
Adt
Orthopedics,
Sen
LLC
200
209
Sen
Utah
Mini Stem Radiostereometric
Analysis Study
NCT01064531
Taperloc® Microplasty™ Hip
System
NCT00699309
Mini Stem DEXA (Dual Energy Xray Absorptiometry)
NCT01066936
Discovering the Gene(s) Causing
Developmental Dysplasia of the
Hip
study
NCT01193673
R3® Acetabular System in
Patients With Degenerative Hip
Disease
Prospective study
NCT01407029
Balance® Microplasty™ Hip
System
NCT00699088
Systemic Effects of Chronic Metal
Ion Exposure From Metal-on Metal
Hip Resurfacing
NCT01493141
Osteoarthritis, Hip
4
Child Jun-09 Sep-15 Smith &
Adt
Nephew, Inc.
Sen
Osteoarthritis;
Active,
Avascular Necrosis
98
Adt Aug-05 Jun-15 Biomet
Sen
Orthopedics,
LLC
Osteoarthritis, Hip
20
Child Aug-09 Apr-15 Smith &
Adt
Nephew, Inc.
Sen
Focus on Patients
Who Have Hip
Dysplasia and Their
Family
Rec
Rec
200 Child Jan-10 Jan-15 University of
Adt
Utah
Sen
158
Adt Oct-09 Dec-14 Smith &
Sen
Nephew, Inc.
Active,
Avascular Necrosis
70
Adt Jan-05 Jun-14 Biomet
Sen
Orthopedics,
LLC
Osteoarthritis
70
Adt Nov-09 Apr-14 Sheffield
Sen
Teaching
Hospitals NHS
Foundation
Trust; NIHR
Biomedical
Research Unit
for
Musculoskeletal
Disease
Osteoarthritis
Active,
NR
Rec
Active,
NR
210
Genetic Factors Affecting Risks for
Rotator Cuff Disease
study
NCT01193647
THRA_hematologic Variables
NCT01521858
Studying the Genetic Invite
Relationship of
Rotator Cuff Tears
400
Adt
Sen
Avascular Necrosis
of Hip
Rec
73
Measured Hypocretin Levels and
Recovery After Hip Surgery
NCT01009710
Psychological, Sexually and Social
Consequences of Osteoarthritis
Treatment With THA or TKA and
Joint Preserving Surgery
NCT01305759
Osteoarthritis, Hip
Invite
50
Adt Jan-12 Jan-13 Seoul National
Sen
University
Bundang
Hospital
Adt Jul-09 Nov-12 Stanford
Sen
University
Total Hip Registry
NCT01133249
Osteoarthritis
Study of Brain and Spinal Cord
Tumor Growth and Cyst
Development in Patients With Von
Hippel Lindau Disease
NCT00005902
Avascular Necrosis (AVN) LongTerm Follow-up
NCT00833430
Digital Sizing for Orthopaedic Hip
Implants
NCT00665210
Hemangioblastoma;
Hippel Lindau
Disease
Active,
NR
Avascular Necrosis;
Femoral Head
Collapse
Hip Arthritis
Term
35
Rec
100 Child Oct-07 Oct-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00665210
Adt
Research
Sen
Institute
Osteoarthritis;
Depression; Hip
Dysplasia
Active,
NR
Invite
Jul-09
Utah
250 Child Apr-10 Apr-12 Hvidovre
Adt
University
Hospital;
Frederiksberg
University
Hospital; Aarhus
University
Hospital;
University
Hospital Koge
942 Adt Jul-05 Feb-12 Heekin
Sen
Orthopedic
Research
Institute; Stryker
Orthopaedics;
DePuy
Orthopaedics;
ConforMIS, Inc.
250 Child Jun-00 Jan-12 National Institute http://ClinicalTrials.gov/show/NCT00005902
Adt
of Neurological
Sen
Disorders and
Stroke (NINDS)
211
Adt Jun-06 Dec-11 Zimmer, Inc.
Sen
Clinical Outcome of Birmingham
Hip Resurfacing (BHR) Using
VISIONAIRE Femoral Alignment
Guide
Prospective study
NCT01427361
Osteoarthritis
Rec
25
Mesenchymal Stromal Cells and
Osteoarthritis
NCT01038596
Osteoarthritis
Rec
30
Modified Triple Osteotomy for
Acetabular Dysplasia
NCT01285154
Sharp Angle; Center Rec
Edge Angle;
Femoral Head
Extrusion Index;
Center Head
Distance
Discrepancy
Staphylococcal
Not yet
Infections;
Rec
and shoulder
Prosthetic Joint
Infection (PJI)
NCT01144000
Predictive Factors for the
Development of Osteonecrosis
After the Treatment of the
Developmental Dislocated Hip
NCT01133938
Predictors of
Comp
Osteonecrosis of the
Femoral Head After
Treatment of the
Dislocated Hip
2
60
79
212
Adt Oct-09 Aug-11 Smith &
Sen
Nephew, Inc.;
Jason Jones,
MS, Group
Director, Clinical
Affairs,
Smith&Nephew
Adt Jan-09 Jun-11 Dresden
Sen
University of
Technology;
German Federal
Ministry of
Education and
Research;
Center for
Regenerative
Therapies
Dresden (CRTD)
Child Feb-11 Jun-11 National Taiwan http://ClinicalTrials.gov/show/NCT01285154
Adt
University
Sen
Hospital
Sen
Hospitalier
Universitaire
Vaudois;
University of
Lausanne
Hospitals;
Kantonsspital
Liestal;
Schulthess Klinik
Child Jan-09 May-10 Orthopedic
Hospital Vienna
Speising
A9. KNEE
A9A: PAEDIATRICS
Title
CT ID
Device
Stapling Versus 8plate for
Correction of Genu Valgus
NCT01528553
Efficacy of Instrumental
Chiropractic Treatment Using
Activator Methods for Pain and
Dysfunction in Juvenile Athletes
RCT, efficacy study
NCT01449994
Interventions
Conditions
Recruit
n
Age Start
(Grp) Date
Device: 8plate;
Device: Staples
(Richards, Smith &
Nephew)
Device: Activator IV
(Activator Methods
Int. Phoenix,
Arizona)
Deformity; Genu
Valgus
Active
NR
20
Child Aug-09 Aug-12 University of
Aarhus
Pain in Leg,
Unspecified; Knee
Sprain
Comp
26
Child Jul-10 Feb-12 Medical
University of
Graz
50
Child Dec-10 Apr-13 University of
British Columbia
64
Child Dec-09 Apr-12 Capio Research http://www.controlledFoundation
(Sweden)
Procedure
The Effect of Femoral Nerve Block Procedure:
Pain, Postoperative
Rec
on Postoperative Opioid Use After Administration of a
Anterior Cruciate Ligament (ACL) femoral nerve block
Reconstruction
(bupivacaine HCL)
study
NCT00175630
Conservative versus arthroscopic Conservative
Dislocation of Patella Active
refixation of the Medial
(orthosis) treatment;
PatelloFemoral Ligament (MPFL) arthroscopic
after traumatic first time dislocation refixation of the
of the patella in children
MPFL with the use of
RCT, efficacy study
anchors
ISRCTN39959729
213
End Sponsors
Date
URL
Title
CT ID
Procedure
Effect of Low-Magnitude, High
Frequency Vibration Treatment on
Femoral Shaft Fracture Healing
Phase II/III: RCT, efficacy
studyNCT01386749
Interventions
Conditions
Recruit
n
Rec
50
Adt Feb-11 Dec-13 Chinese
University of
Hong Kong
Intra-articular Knee
Fractures
Active,
NR
40
Adt Dec-06 Mar-12 Greenville
Sen
Hospital System
University
Medical Center;
Orthopaedic
Trauma
Association
Conditions
Recruit
n
Rec
60
Procedure: vibration Fracture, Closed,
platform provide low Comminuted,
magnitude and high Healing
frequency vibration
treatment, which is
self-developed by
our research team
Other
Use of Continuous Passive Motion Other: Continuous
in the Post-Operative Treatment of Passive Motion
Intra-articular Knee Fractures
RCT
NCT00591929
Age Start
(Grp) Date
End Sponsors
Date
URL
A9C: ARTHROSCOPY
Title
CT ID
Device
Intra-articular Hyaluronan After
Arthroscopic Meniscal Surgery
NCT01482624
Interventions
Device: Hyaluronan Arthroscopic
(0.5%, 5 mg/10 ml); Meniscal Surgery
Procedure: Standard
arthroscopic
meniscal surgery
214
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt Dec-11 Jan-13 TRB Chemedica http://ClinicalTrials.gov/show/NCT01482624
Sen
AG
Autologous Chondrocyte
Device: Arthroscopic Tear; Knee,
Transplantation For Articular
matrix encapsulated Cartilage, Articular
Cartilage Regeneration
chondrocyte
implantation
study
NCT01503970
The treatment of medial
KineSpring™
Medial Knee OA
compartmental knee osteoarthritis Unicompartmental
(OA) symptoms with the
Knee Arthroplasty
KineSpring™ Unicompartmental (UKA) System
Knee Arthroplasty (UKA) System
(historical control)
ISRCTN63048529
A Prospective Randomized Study Device: Vanguard
Total Knee
on Vanguard Cruciate Retaining PS Knee; Device:
Arthroplasty
Versus Vanguard High Flex
Vanguard CR Knee
Posterior Stabilized Total Knee
System in the Early Range of
Motion
NCT00763113
Effects of TENS Therapy Following Device: TENS
Meniscus Tear
Arthroscopic Knee Surgery
Treatment with
RCT, efficacy study
functional or disabled
NCT01528228
unit
Temperature Sensitive Release of Device: Cooling and Knee Arthroscopy;
PGE2 and Diminished Energy
compression
Meniscus;
Requirements in Synovial Tissue
Inflammation;
With Postoperative Cryotherapy Hydrops; Cooling
A Prospective Randomised Study
After Knee Arthroscopy
RCT, efficacy study
NCT01247376
Active,
NR
10
Adt Dec-08 Dec-12 Instituto
Nacional de
MRehabilitacion;
only
National Council
of Science and
Technology,
Mexico
Adt Sep-09 Jun-12 Moximed Inc.
(USA)
Active
30
Active,
NR
173 Child Jun-07 Jun-12 Biomet, Inc.
Adt
Sen
Invite
20
Adt
Jul-11 Apr-12 A.T. Still
University of
Health Sciences
Comp
40
Adt
Jan-08 Jun-10 Karolinska
Institutet
215
Comparison of a Pain Pump
Versus Injectable Medication for
Analgesia in Knee Arthroscopy
Phase II: RCT
NCT01242644
Device: pain pump Pain
containing
ropivacaine; Device:
saline pain pump
with injectable
medication; Drug:
ropivacaine,
ketorolac , morphine
sulfate
Pot-Kast: Thrombosis Prophylaxis Drug: LMWH
After Knee Arthroscopy
RCT, efficacy study
NCT01542723
Comp
49
Deep Venous
Thrombosis;
Pulmonary
Embolism
Adt Oct-06 Jun-10 University of
Sen
South Alabama
Not yet 1500 Adt Apr-12 Apr-16 Suzanne C.
Rec
Sen
Cannegieter, MD
PhD; ZonMw:
The Netherlands
Organisation for
Health Research
and
Development
Autologous Tolerogenic Dendritic Drug: TolDC; Drug: Rheumatoid Arthritis Not yet 12
Adt Aug-11 Aug-13 Newcastle
Cells for Rheumatoid Arthritis
Arthroscopy & saline
Rec
Sen
University;
(AutoDECRA)
irrigation alone
Arthritis
Research UK
NCT01352858
(funder);
Newcastle-uponTyne Hospitals
NHS Trust
Safety and Efficacy of
Drug: OMS103HP-S; Meniscal Tear
Rec
330 Adt Aug-11 Jun-12 Omeros
OMS103HP-S Administered in
Drug: Vehicle
Sen
Corporation
Joint Irrigation Solution to Subjects
Undergoing Arthroscopic
Meniscectomy
study
NCT01406561
Safety and Effectiveness of
Drug: extendedPostoperative Pain Not yet 100 Adt Dec-09 Dec-11 Shaare Zedek
Tramadex-OD After Knee
release tramadol;
Rec
Medical Center
Arthroscopy
Drug: paracetamol
NCT01024348
216
Infrapatellar Nerve Block for Postoperative Knee Arthroscopy Pain
Control
NCT01279447
Selective Unilateral Spinal
Anesthesia Versus Selective
Sensory Spinal Anesthesia for
Knee Arthroscopy Surgery
study
NCT01356797
The Analgesic Effect of Intrathecal
Hydromorphone Injection on
Spinal Anesthesia
RCT, efficacy study
NCT01172782
Procedure
Development of Knee
Osteoarthritis After Arthroscopic
Partial Resection of Degenerative
Meniscus Tear
NCT01052233
Surgical or Exercise Therapy on
Patients With Degenerative
Meniscus Tears
NCT01002794
Drug: 0.25%
Bupivacaine; Drug:
Normal Saline
Knee Pain; Knee
Derangement
Syndrome; Knee
Arthroscopy
Rec
70
Adt Jan-11 Oct-11 Northwestern
Sen
University
Drug: hypobaric
Pain
levobupivacaine with
fentanyl; Drug:
hyperbaric
bupivacaine 0,5%
Comp
54
Adt May-11 Sep-11 USP Hospital La http://ClinicalTrials.gov/show/NCT01356797
Sen
Colina
Drug:
Hydromorphone
Pain Measurement;
Visual Analog Pain
Scale; knee
arthroscopic surgery
Comp
60
Adt
Sen
Procedure:
Arthroscopic partial
meniscectomy;
Procedure:
Arthroscopy
(diagnostic)
Knee; Arthroscopy;
Meniscal Tear
Rec
160
Adt
340
Adt May-08 Aug-16 Brigham and
Sen
Women's
Hospital
Procedure:
Degenerative
Arthroscopic partial Meniscus Tear
menisectomy; Other:
Supervised
neuromuscular and
strength training
Comparing Knee Cartilage Surgery Procedure:
Osteoarthritis
Versus Standard Physical Therapy Arthroscopic partial
in Treating People With a Meniscal menisectomy; Other:
Tear and Osteoarthritis
Standard physical
Phase II: RCT
therapy; Other:
NCT00597012
Postoperative
rehabilitative physical
therapy
Rec
Active,
NR
217
Jul-09
Jul-10 Korea University http://ClinicalTrials.gov/show/NCT01172782
Anam Hospital;
Korea University
Jan-10 Jan-24 University of
Tampere;
Helsinki
University
Central Hospital;
Turku University
Hospital; Kuopio
University
Hospital; Central
Finland Hospital
District
Adt Nov-09 Dec-16 Oslo University http://ClinicalTrials.gov/show/NCT01002794
Hospital;
University of
Southern
Denmark
The Benefit of Arthroscopic Partial
Meniscectomy in Middle-Aged
Patients
RCT, efficacy study
NCT01264991
Arthroscopic Debridement for
Chondral Lesions in the Knee
RCT
NCT01527201
Arthroscopy in the Treatment of
Degenerative Medial Meniscus
Tear
NCT00549172
Procedure:
Arthroscopic partial
meniscectomy;
Procedure: Sham
procedure
Procedure:
Arthroscopic
debridement
Degenerative
Meniscus Tear
Rec
150
Meniscal Tear;
Chondromalacia
Rec
190
Active,
NR
140
Rec
150
Rec
72
Adt Nov-10 Apr-12 Glostrup
Sen
University
Hospital,
Copenhagen
Active,
NR
10
Comp
21
Adt Feb-06 Feb-12 State University http://ClinicalTrials.gov/show/NCT00643487
Sen
University
Adt Jun-11 Jan-12 Northern
Sen
Orthopaedic
Division,
Denmark
Procedure: Operative Degenerative Tear
(partial arthroscopy); of the Medial
Procedure:
Meniscus of Knee
Conservative
(diagnostic
arthroscopy)
Is a Knee Arthroscopy of Any
Procedure: Knee
Injury;Meniscus;Chr
Benefit for the Middleaged Patient arthroscopy
onic
With Meniscal Symptoms?
RCT, efficacy study
NCT01288768
The Efficacy of Adductor-CanalProcedure: Adductor- Meniscus Lesion;
Block (ACB) in Patients After Knee Canal-Block,
Pain (Knee);
Arthroscopy
Ropivacain;
Diagnostic Knee
Phase IV: RCT, safety/efficacy Procedure: Adductor Artroscopy; Minor
study
Canal Block, Placebo Knee Surgery
NCT01254825
(saline)
In Vivo Arthroscopic Behavior of Procedure:
Patellofemoral Pain
the Infrapatellar Plica of the Knee observation of the
Syndrome
behavior of the
NCT00643487
infrapatellar plica
Topical Lidocaine After Major
Procedure: Sham
Fracture of Patella;
Arthroscopic Knee Surgery
operation;
Pain
RCT, efficacy study
Procedure: Knee
NCT01509729
arthroscopic surgery
218
Adt Dec-10 Nov-15 Slagelse
Hospital;
University of
Southern
Denmark
Adt Jan-12 Jan-15 State University http://ClinicalTrials.gov/show/NCT01527201
Sen
of New York at
Buffalo
Adt
Oct-07 Jan-14 University of
Tampere;
Helsinki
University
Central Hospital;
Kuopio
University
Hospital; Turku
University
Hospital; Central
Finland Hospital
District
Adt Mar-10 Dec-12 University
Hospital,
Linkoeping
HTO With and Without
Arthroscopy
study
NCT00284622
Evaluation of MRI Diagnosed
Meniscal Lesions
NCT01492855
Procedure:
Arthroscopy
Medial Compartment Not yet
Rec
Knee
98
Adt Dec-09 Dec-11 Fowler Kennedy http://ClinicalTrials.gov/show/NCT00284622
Sen
Sport Medicine
Clinic
Procedure:
Arthroscopy;
Behavioral: Noninvasive treatment
Meniscus Lesion
Comp
324
Adt Jan-08 Dec-10 Northern
Sen
Orthopaedic
Division,
Denmark
Rec
30
Sen
Oulu; Oulu
University
Hospital;
University of
Eastern Finland;
Kuopio
University
Hospital
Term
32
Adt May-08 May-10 National Institute http://ClinicalTrials.gov/show/NCT00752271
Sen
on Aging (NIA)
Other
Clinical Study of Novel Diagnostic Other: Intra-articular Knee Osteoarthritis;
Techniques for Knee Osteoarthritis ultrasound imaging Knee Injuries
of knee joint during
study
arthroscopy; Other:
NCT01359553
Non-invasive
ultrasound imaging
of knee; Other:
Quantitative MRI
imaging of knee;
Other: Contrastenhanced CT
imaging of knee
AMS Study: Inflammatory and
Biomechanical Contributors to
Arthritis Development Following
Arthroscopic Meniscectomy
NCT00752271
Osteoarthritis
219
A9D: CRUCIATE LIGAMENT PATHOLOGIES
Title
Interventions
CT ID
Device
Safety and Efficacy Study of the Z- Device: Z-Lig;
Lig Medical Device Compared to Device: Allograft
Allograft
NCT01245400
Conditions
Recruit
n
Age Start
(Grp) Date
Ruptured Anterior
Cruciate Ligaments
Rec
60
Safety and Efficacy of the Knee-T- Device: Knee-T-Nol Anterior Cruciate
nol Anterior Cruciate Ligament
Ligament Rupture
(ACL) Prosthesis
NCT01450332
Therapeutic Effects of Cryotherapy Device: cryotherapy Anterior Cruciate
and Transcutaneus Nerves
Ligament Injury
Stimulation on Arthrogenic Muscle
Inhibition in Patients With Anterior
Cruciate Ligament Reconstruction
NCT01273649
Evaluation of Biocleanse Allografts Device: ACL
Cruciate Ligament,
For ACL Reconstruction
reconstruction
Anterior; Allograft
NCT00187876
Weight-bearing Measuring Device Device: Smart_Step Weight-bearing
Following Anterior Cruciate
weight bearing insole Deficits
Ligament Reconstruction
NCT01127685
Rec
20
Adt Nov-10 Aug-13 Aperion
Biologics, Inc.;
MedPass
International;
Contract
Research
Organization
Adt Mar-11 Jan-13 Tavor Ltd.
Rec
30
Adt
Monly
End Sponsors
Date
URL
Jan-11 Dec-11 National Taiwan http://ClinicalTrials.gov/show/NCT01273649
University
Hospital
Comp
138
Adt Feb-04 Jul-11 University of
Florida
Comp
30
Adt May-10 Jul-11 Meir Medical
Sen
Center
220
SeriACL™ Device (Gen IB) Trial
for Anterior Cruciate Ligament
(ACL) Repair
study
NCT00775892
Triathlon Cruciate Retaining (CR)
Outcomes Study
NCT00957723
Device: SeriACL
Device ACL
Reconstruction
Anterior Cruciate
Ligament
Reconstruction
Comp
30
Adt Sep-08 May-10 Serica
Technologies,
Inc.
Device: Triathlon
(CR) Total Knee
System
Arthropathy of Knee
Joint; Osteoarthritis,
Knee; Avascular
Necrosis of Bone
Active,
NR
500
Adt Feb-05 Apr-10 Stryker
Sen
Orthopaedics
Anterior Cruciate
Ligament Injury;
Osteoarthritis
Rec
24
Adt Mar-09 Jun-14 Mesoblast, Ltd.
Pain
Rec
120
Adt Feb-09 Apr-13 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01186887
Sen
Research
Institute; Pfizer
Rupture of the
Anterior Cruciate
Ligament With
Instability of the
Knee Joint.
Rec
75
Adt
Sen
Safety and Efficacy Study of MSB- Biological: MSBCAR001 in Subjects 6 Weeks Post CAR001 Combined
an Anterior Cruciate Ligament
With Hyaluronan;
Reconstruction
Drug: Hyaluronan
study
NCT01088191
A Trial Assessing the Outcome of Drug: Celecoxib;
Celecoxib Administration Versus Drug: Placebo
Placebo Following Anterior
Cruciate Ligament (ACL)
Reconstruction
RCT, efficacy study
NCT01186887
Evaluation of Arthroscopic
Drug: injection in the
Reconstruction of the Anterior
knee joint with 20 ml
Cruciate Ligament by One Night of chirocaine
Hospital Stay or by Day Surgery: a 0.125%; Drug:
Randomised, Prospective Clinical injection in the knee
Trial
joint with 20 ml of
Phase IV: RCT
physiological fluid
NCT00620477
Efficacy and Safety of OMS103HP Drug: OMS103HP;
in Patients Undergoing Allograft
Drug: Vehicle
Anterior Cruciate Ligament (ACL)
Reconstruction
study
NCT00226759
Knee Injuries
Comp
Jul-08 Dec-11 University
Hospital, Ghent
280 Child Nov-04 Mar-11 Omeros
Adt
Corporation
221
Efficacy and Safety of OMS103HP
in Patients Undergoing Autograft
Reconstruction
study
NCT00226772
Safety of OMS103HP in Patients
Undergoing Anterior Cruciate
Ligament (ACL) Reconstruction
NCT00245271
Perioperative Administration of
Pregabalin in Patients Undergoing
Arthroscopic Anterior Cruciate
study
NCT01242332
A Randomized, Double Blind,
Placebo-controlled Study to
Assess the the Preemptive Benefit
of Etoricoxib in Patients Receiving
Anterior Cruciate Ligament
Reconstruction
study
NCT00554346
Procedure
Comparison of Three Methods for
Reconstruction
RCT
NCT00529958
Drug: OMS103HP;
Drug: Vehicle
Knee Injuries
Comp
280 Child Jun-05 Mar-11 Omeros
Adt
Corporation
Drug: OMS103HP;
Drug: Vehicle
Anterior Cruciate
Ligament
Reconstruction
Comp
480 Child Oct-04 Mar-11 Omeros
Adt
Corporation
Drug: Pregabalin
Postoperative Pain
Management
Comp
60
Drug: Arcoxia
(Etoricoxib 90
mg/tablet)
Post-operational
Pain
Comp
64
Procedure: Patellar
Tendon; Procedure:
Hamstring Tendon;
Procedure: DoubleBundle
Anterior Cruciate
Ligament Rupture;
Deficiency of
Anterior Cruciate
Ligament; Chronic
Instability of Knee;
Anterior Cruciate
Ligament Injury
Active,
NR
231 Child Sep-07 Dec-20 University of
Adt
Calgary;
Workers'
Compensation
Board - Alberta
222
Adt Aug-09 Oct-10 Prince of
Songkla
University
Child May-08 Jun-10 National Taiwan http://ClinicalTrials.gov/show/NCT00554346
Adt
University
Hospital; Merck
Single- vs. Double-Bundle ACL
Reconstruction
NCT01319409
Procedure: Anatomic Anterior Cruciate
Double-Bundle ACL Ligament Injury
Reconstruction;
Procedure: Anatomic
Single-Bundle ACL
Reconstruction
Rec
Reconstruction: Residual
Rotational Laxity for Single Versus
Double Bundle Techniques
RCT, efficacy study
NCT01377129
Procedure: Single
bundle anterior
cruciate ligament
reconstruction;
Procedure: Double
bundle anterior
cruciate ligament
reconstruction
Procedure: ACL
reconstruction
Anterior Cruciate
Ligament Injury
Rec
Anterior Cruciate
Ligament; Injury
Rec
Comparison of Doubled
Quadrupled Versus Quadrupled
Allograft Tissue Constructs for
Reconstruction
RCT
NCT01148784
Initial Graft Tension and ACL
Surgery
RCT, efficacy study
NCT00434837
Femoral Neuropathy After Anterior
Cruciate Ligament Reconstruction:
Femoral Nerve Block vs Patientcontrolled Analgesia (PCA)
RCT
NCT01321138
Reconstruction Using Different
Grafts and Surgical Techniques
Phase IV: RCT
NCT00300300
160 Child Mar-11 Feb-16 University of
Adt
Pittsburgh;
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
54
Adt Oct-11 Oct-15 Centre
Sen
Hospitalier
Universitaire de
Nīmes
100
Adt Jun-10 Jun-14 Oregon Health
Sen
and Science
University
Procedure: Initial
Anterior Cruciate
Active,
graft tension during Ligament Rupture
NR
ACL reconstruction
surgery
Procedure: Femoral Femoral Neuropathy Rec
nerve block;
Procedure: PCA
morphine
168 Child Feb-04 May-14 Rhode Island
Adt
Hospital (US)
120 Child Apr-11 Nov-13 Centre
Adt
Hospitalier
Universitaire
Vaudois
Procedure:
Computer-assisted
surgery
125
Anterior Cruciate
Ligament
Reconstruction
Susp
223
Adt Sep-09 Sep-13 Queen's
University
Reconstruction: Single Bundle
Versus Double Bundle
Phase IV: RCT
NCT01025895
Procedure: acl
reconstruction double bundle
technique;
Procedure: acle
reconstruction single bundle
technique
Lumbar Plexus Catheter Versus
Procedure: lumbar
Femoral Nerve Catheter for
plexus catheter;
Postoperative Pain After Anterior Procedure: femoral
Cruciate Ligament (ACL) Repair nerve catheter;
RCT, efficacy study
Procedure: singleNCT01068275
shot femoral block
The effect of prehabilitation on the Prehabilitation
outcome of anterior cruciate
exercise group;
ligament reconstruction
standard pre- and
RCT, efficacy study
post-operative care
ISRCTN60779921
Double Bundle Anterior Cruciate Procedure: Single
Bundle; Procedure:
RCT, efficacy study
double bundle
NCT01033188
Pain Evaluation After Anterior
Procedure: “AllCruciate Ligament (ACL)
inside"; Procedure:
Ligamentoplasty
“Classical technique"
Phase IV: RCT
NCT01448278
Single Bundle Anterior Cruciate
Procedure: anterior
Ligament Reconstruction in Active cruciate ligament
Young Men
reconstruction
RCT
NCT01533025
Comparison of Infiltration
Procedure:
Analgesia With Femoral Nerve
applicationsite
Block After Hamstrings Anterior
RCT, efficacy study
NCT01260363
Anterior Cruciate
Ligament Tear
Postoperative Pain
Not yet
Rec
Rec
60
Child Jan-10 Jan-13 Assaf-Harofeh
Adt
Medical Center
114 Child Apr-10 Sep-12 Seattle
Adt
Children's
Hospital
30
Jan-11 Jun-12 Cappagh
National
MOrthopaedic
only
Hospital
(Ireland)
150 Adt Nov-09 Jun-12 Ullevaal
University
Hospital
Anterior cruciate
ligament tear
Active
Knee Instability
Rec
Arthroscopic Anterior
Cruciate Ligament
Reconstruction
Rec
45
Adt Nov-10 May-12 Hôpital
Sen
Ambroise Paré
Anterior Cruciate
Ligament Rupture
Comp
72
Adt Aug-08 Jan-12 National Police
Hospital
Monly
Anterior Cruciate
Ligament
Recontruction
Rec
60
Sen
Aarhus
224
Adt
Reconstruction Using Single
Bundle and Double Bundle
Techniques
RCT, efficacy study
NCT01358656
Procedure: Single
Anterior Cruciate
bundle anterior
Ligament Injury
cruciate ligament
reconstruction;
Procedure: Double
bundle anterior
cruciate ligament
reconstruction
Preservation technique of ruptured Semitendinosus
Ruptured Anterior
anterior cruciate ligament (ACL)
transplant; Dynamic Cruciate Ligament
RCT, efficacy study
intraligamentary
ISRCTN89368687
stabilisation
technique
Use of Graft Tensioner Device in Procedure: ACL
Torn Anterior
ACL (Knee) Repair
surgery
Cruciate Ligament
RCT, efficacy study
(Knee)
NCT00221273
The Efficacy of Adductor-CanalProcedure:
Anterior Cruciate
Block (ACB) in Patients After
Ropivacain;
Ligament
Anterior Cruciate Ligament (ACL) Procedure: Saline
Reconstruction
Reconstruction
NCT01212666
Femoral Tunnel Position on
Transtibial technique; Anterior Cruciate
Conventional MRI After Anterior
Transportal
Ligament Rupture
Cruciate Ligament Reconstruction- technique; anterior
Transtibial Technique Versus
cruciate ligament
Transportal Technique
reconstruction
NCT01513434
Clinical Outcome of Posterior
Procedure: PCL,
Knee Injuries
Cruciate Ligament (PCL)
posterolateral
Posterolateral Reconstruction
reconstruction
NCT00991588
Prospective Evaluation of Femoral Procedure: Sciatic
Anterior Cruciate
Versus Femoral and Sciatic Nerve Block; Procedure:
Ligament
Block for Ambulatory Anterior
Femoral Block only Reconstruction
Cruciate Ligament (ACL)
Reconstruction
RCT, efficacy study
NCT01447277
Rec
40
Adt
Jan-10 Jan-12 Vita Care
Comp
100
Active,
NR
130
Adt Aug-08 Jan-12 Swiss National http://www.controlledSen
Insurance
Association
(SUVA)
(Switzerland)
Sen
British Columbia
Rec
50
Adt May-10 Nov-11 Glostrup
Sen
University
Hospital,
Copenhagen
Comp
64
Child Jul-08 Nov-11 National Police
Adt
Hospital
Monly
Invite
20
Rec
225
Child Oct-09 Oct-11 Cincinnati
Adt
Sportsmedicine
Sen
Research and
Education
Foundation
Sen
California, San
Francisco;
Joshua Cohen
MD
Simultaneous Multiple Cruciate
Procedure: cruciate Rupture of Posterior
Ligament Reconstructions Using a ligament
Cruciate Ligament;
Single Achilles Allograft
reconstruction
Rupture of Anterior
Cruciate Ligament
assignment
NCT01440348
Hamstrings Autograft Versus
Procedure: autograft Rupture of the
Tibialis Allograft for Reconstruction tendon; Procedure: Anterior Cruciate
of Anterior Cruciate Ligament
allograft tendon
Ligament With
RCT, efficacy study
Instability of the
NCT00510848
Knee Joint
Stability of the Knee Joint After
Procedure:
Rupture of Anterior
Single and Double Bundle Anterior 'biomechanic of the Cruciate Ligament
Cruciate Ligament Reconstruction knee'
RCT, efficacy study
NCT01391650
Computer assisted surgery versus Arthroscopic ACL
Rupture, anterior
conventional arthroscopic anterior reconstruction with cruciate ligament
cruciate ligament reconstruction: a computer assisted
prospective randomised clinical
surgery; conventional
trial
Arthroscopic ACL
RCT (active), efficacy study
reconstruction
ISRCTN40231111
Clinical Trial Comparing Three
Procedure: Three
Knee Injuries
anterior cruciate
Reconstructive Procedures
ligament
RCT, efficacy study
reconstructive
NCT00418964
procedures
Evaluation of Tibial and Femoral Procedure: Anterior Anterior Cruciate
Tunnel Position After Arthroscopic cruciate ligament
Ligament Rupture
Reconstruction of the Anterior
reconstruction
Cruciate Ligament
assignment
NCT01267435
Comp
51
Child May-11 Sep-11 National Police
Adt
Hospital
Sen
Monly
Adt Aug-07 Aug-11 University
Sen
Hospital, Ghent
Rec
40
Comp
60
Adt Mar-10 May-11 Hospital Znojmo; http://ClinicalTrials.gov/show/NCT01391650
Masaryk
University
Comp
90
Adt Dec-06 Dec-10 Erasmus
Sen
Medical Centre
(The
Netherlands)
Rec
42
Adt Dec-06 Nov-10 Chinese
University of
Hong Kong
Comp
40
226
Child Oct-08 Mar-10 Isfahan
Adt
University of
Sen
Medical
Sciences (Iran)
Other
Dynamic Stability of the Anterior
Cruciate Ligament (ACL) Deficient
Knee
NCT00696319
Exercise protocol
Knee Injury
with perturbation
exercises; Exercise
protocol with
traditional exercises
for stability and
balance.
Ultrasound Guided Obturator
Other: Sciatic,
Anterior Cruciate
Nerve Block for Anterior Cruciate femoral, obturator
Ligament; Surgery
Ligament Reconstruction (ACL)
nerve blocks; Other:
Sciatic nerve block,
NCT01194505
posterior lumbar
plexus block
BioCleanse Tibialis Tendon
Other: BioCleanse Anterior Cruciate
Anterior Cruciate Ligament (ACL) Tibialis tendon;
Ligament Rupture
Study
Other: Tibialis
Tendon Allograft
NCT00975845
from donor 65-75
years of age
Changes in Muscle Morphology
Other: Autograft STG Isolated Anterior
Resulting From Anterior Cruciate harvest from ACL- Cruciate Ligament
deficient leg; Other: Rupture
RCT
Autograft harvest
NCT01537588
contralateral to ACLdeficient leg
The Effect of Early Whole Body
Other: Whole body Rupture of Anterior
Vibration Therapy After Anterior
vibration therapy;
Cruciate Ligament
Cruciate Ligament Reconstruction Other: Control
RCT, efficacy study
NCT01300182
Proprioceptive Function, Postural Other: conventional Ruptured Anterior
Stability & Clinical Outcome After ACL rehabilitation
Cruciate Ligament;
Stump Preserving Anterior
program
Partial Tear
Ligament
Surgery
RCT
NCT01348945
Susp
150 Child Jan-07 Jun-13 Ullevaal
Adt
University
Hospital;
University of
Delaware
Rec
100
Adt
Rec
40
Adt Dec-09 Apr-13 RTI Biologics
Active,
NR
30
Adt
Rec
48
Active,
NR
48
227
Jun-10 May-13 Larissa
University
Hospital
Jul-09
Jul-12 Panam Clinic
Child Nov-10 Jun-12 Chinese
Adt
University of
Sen
Hong Kong;
Hospital
Authority
Adt May-11 Feb-12 Chinese
Sen
University of
Hong Kong
Quadriceps Function Prior to
Reconstruction
RCT, efficacy study
NCT00971451
Other: cryotherapy;
Other: TENS
Multicenter Orthopaedics
Outcomes Network for ACL
Reconstructions
NCT00463099
Rupture of Anterior
Cruciate Ligament
Rec
Rupture of Anterior
Cruciate Ligament
Invite
Multicenter Orthopaedic Outcomes
Network (MOON) ACL
Reconstruction (ALCR): Onsite
Follow-up
NCT00478894
Rupture of Anterior
Cruciate Ligament;
Osteoarthritis
Results of Knee Arthroscopic
Surgery for Treatment of Cruciate
Ligament and Meniscus
Retrospective
NCT01453673
Multicenter ACL Revision Study
(MARS)
NCT00625885
Reconstruction- Bioabsorbable
Screw
NCT01069588
Knee Arthroscopic
Surgery
50
Child Nov-07 Dec-11 University of
Adt
Virginia
5000 Child Jan-07 Dec-16 Vanderbilt
Adt
University;
National
Institutes of
Health; National
Institute of
Arthritis and
Musculoskeletal
and Skin
Diseases
Invite 400 Child Aug-07 Aug-14 Vanderbilt
Adt
University;
National
Institutes of
Health; National
Institute of
Arthritis and
Musculoskeletal
and Skin
Diseases
Active, 210 Adt May-11 May-13 Taipei Medical http://ClinicalTrials.gov/show/NCT01453673
NR
Sen
University
WanFang
Hospital
Anterior Cruciate
Ligament
Invite
800 Child Feb-07 Nov-12 Vanderbilt
Adt
University
ACL Reconstruction
Invite
100 Child Dec-09 Feb-12 Vanderbilt
Adt
University; Smith
& Nephew, Inc.
228
Follow up of Patients Operated
With Anterior Cruciate Ligament
Reconstruction
Prospective
NCT01279759
Investigation into patient
characteristics and treatment
factors associated with short-term
and medium-term outcome
following Anterior Cruciate
ISRCTN30554985
Normal
management;
Measures to reduce
swelling
Anterior Cruciate
Ligament
Reconstruction
Rec
35
Child Oct-10 Dec-11 Haraldsplass
Adt
Deaconess
Sen
Hospital
Anterior cruciate
ligament
reconstruction
(Arthroscopic)
Comp
100
Adt Apr-06 Mar-10 Department of
Sen
Health (UK)
Recruit
n
Age Start
(Grp) Date
Rec
92
Child Oct-11 Oct-14 Exactech
Adt
Taiwan, Ltd.;
Exactech, Inc.
Rec
40
Adt
Rec
99
Adt Sep-10 Mar-13 The Hawkins
Sen
Foundation;
Ferring
Pharmaceuticals
A9E: MENISCUS/CARTILAGE PATHOLOGIES
Title
CT ID
Device
BiPhasic Cartilage Repair Implant
(BiCRI) IDE Clinical Trial - Taiwan
study
NCT01477008
Interventions
Conditions
Device: BiPhasic
Cartilage Repair
Implant; Procedure:
Marrow Stimulation
Chondral or
Osteochondral
Lesion of Medial
Femoral Condyle;
Chondral or
Osteochondral
Lesion of Lateral
Femoral Condyle;
Chondral or
Osteochondral
Lesion of Trochlea
Device: INSTRUCT Articular Cartilage
Lesion of the Knee
INSTRUCT for Repair of Knee
Cartilage Defects
NCT01041885
Post-op Treatment With Hyaluronic Device: Euflexxa;
Acid Injections
Other: Saline
NCT01256788
Meniscus Tear;
Chondropathy/Dege
nerative Joint
Disease (DJD)
229
End Sponsors
Date
URL
Jan-10 Mar-14 CellCoTec B.V. http://ClinicalTrials.gov/show/NCT01041885
A Prospective, Post-market, Multicenter Feasibility Study of the
BioDuct® Meniscal Repair Device
NCT01270919
ChonDux for Filling Full Thickness
Cartilage Defects in the Femoral
Condyle of the Knee
NCT01110070
Knee Articular Cartilage
Debridement in Conjunction With
Partial Meniscectomy
NCT00613535
Device: BioDuct
Meniscal Repair
Device
Meniscal Repair
Term
35
Adt Nov-10 Jan-13 Stryker
Orthopaedics
Device: ChonDux;
Device: ChonDux
Cartilage Defect
Susp
60
Adt
Jul-10 Jan-13 Biomet, Inc.
Rec
165
Adt
Apr-08 Dec-12 ArthroCare
Corporation
Not yet
Rec
5
Adt
Jul-11 Sep-11 Capital District http://ClinicalTrials.gov/show/NCT01290991
Health Authority,
Canada
Comp
80
Adt Dec-05 May-11 Piramal
Healthcare
Canada Ltd
Rec
76
Adt Aug-10 Dec-13 SK Chemicals
Sen
Co.,Ltd.
Active,
NR
50
Adult Jun-08 Apr-11 Osiris
Therapeutics
Device: Mechanical Torn Meniscus;
debridement; Device: Articular Cartilage
Paragon T2;
Defect
Procedure: Lavage
debridement; Device:
Mechanical
Debridement;
Device: RF- based
Debridement
Device: Augment
Defect of Articular
Bone Graft
Cartilage
A Study to Evaluate the Safety of
Augment™ Bone Graft
study
NCT01290991
Trial Comparing BST-CarGel and Device: BST-CarGel; Knee Injuries
Microfracture in Repair of Articular Device: BST-CarGel
Cartilage Lesions in the Knee
NCT00314236
Assessment of Protective Effect of
JOINS on Cartilage in Knee
Osteoarthritis
study
NCT01293955
Follow-up Study of Chondrogen®
Delivered by Intra-Articular
Injection Following Meniscectomy
study
NCT00702741
Drug: JOINS 200mg; Knee Osteoarthritis
Drug: Placebo
Drug: Chondrogen;
Drug: Chondrogen;
Drug: Placebo
Recovery Following
Partial Medial
Meniscectomy
230
Autologous Transplantation of
Mesenchymal Stem Cells (MSCs)
and Scaffold in Full-thickness
Articular Cartilage
study
NCT00850187
Changes in Knee Articular
Cartilage Volume in Women on
Aromatase Inhibitors
Phase IV: Cross-sectional,
cohort study
NCT00111241
Articular Cartilage Resurfacing
With Mesenchymal Stem Cells In
Osteoarthritis Of Knee Joint
NCT01207661
Procedure
ACI-C Versus AMIC. A
Randomized Trial Comparing Two
Methods for Repair of Cartilage
Defects in the Knee
NCT01458782
Mesenchymal Stem Cells in a
Clinical Trial to Heal Articular
Cartilage Defects
Phase I: RCT
NCT00885729
Cartilage Autograft Implantation
System (CAIS) for the Repair of
Knee Cartilage Through Cartilage
Regeneration
NCT00881023
Biological: Bone
marrow derived
mesenchymal stem
cells
Knee Osteoarthritis
Comp
6
Drug: aromatase
Arthralgia
inhibitors (letrozole,
anastrozole)
Active,
NR
170
Biological:
Mesenchymal
Injection
Osteoarthritis
Comp
Procedure:
Treatment of
cartilage defects in
the knee
Osteochondritis
Dissecans;
Osteoarthritis;
Cartilage Injury;
Osteonecrosis
Procedure: stem
cells; Procedure:
Chondrocytes
Procedure:
Microfracture;
Device: Cartilage
Autograft
Implantation System
Adt Aug-08 Dec-10 Royan Institute; http://ClinicalTrials.gov/show/NCT00850187
Tehran
University of
Medical
Sciences
Adt May-05 Dec-10 Monash
University
Fonly
6
Adt Aug-09 Nov-10 Royan Institute
Rec
80
Adt
Oct-11 Oct-24 University
Hospital of North
Norway;
University of
Tromso
Focal Articular
Fullthickness
Cartilage Defect of
the Knee
Rec
50
Adt
Apr-09 Jul-18 Oslo University
Hospital
Defect of Articular
Cartilage;
Osteochondritis
Dissecans
Rec
364
Adt
Jul-10 Dec-16 DePuy Mitek
231
Efficacy and Safety Study of
co.Don Chondrosphere to Treat
Cartilage Defects
study
NCT01222559
Autologous Chondrocyte
Transplantation/Implantation
Versus Existing treatments
RCT
ISRCTN48911177
Extension Study for Patients Who
Comp Previous Study MACI00206
[NCT00719576] of MACI® Implant
for the Treatment of Symptomatic
Articular Cartilage Defects of the
Femoral Condyle
study
NCT01251588
Confirmatory Study of NeoCart in
Knee Cartilage Repair
study
NCT01066702
Study for the Treatment of Knee
Chondral and Osteochondral
Lesions
NCT01282034
Knee Articular Cartilage Repair:
Cartilage Autograft Implantation
System Versus Conventional
Microfracture
Phase II: RCT
NCT01498029
Procedure:
Articular Cartilage
Microfracture; Drug: Lesion of the
co.don
Femoral Condyle
chondrosphere®
Rec
150
Adt
Oct-10 Jul-16 co.don AG
Autologous
chondrocyte
implantation (ACI);
'conventional'
treatment
(Debridement;
Abrasion; Drilling;
Microfracture;
Mosaicplasty)
Procedure:
Microfracture;
Biological: MatrixInduced Autologous
Chondrocyte Implant
(MACI® Implant)
Symptomatic
chondral defect(s)
on medical or lateral
femoral condyle or
trochlea
Active
660
N/K Dec-04 Mar-16 Keele University http://www.controlled(UK)
trials.com/ISRCTN48911177/
Repair of Articular
Cartilage Defects
Invite
144
Adt Dec-10 May-15 Genzyme
Procedure:
Microfracture;
Biological: NeoCart
Cartilage Defects of
the Femoral Condyle
Rec
245
Adt May-10 Mar-15 Histogenics
Corporation
Procedure: Marrow
stimulation - Drilling
or Microfractures;
Device: MaioRegen
Surgery
Procedure:
Microfracture;
Device: Cartilage
Autograft
Implantation System
(CAIS)
Knee Chondral
Lesion; Knee
Osteochondral
Lesion
Rec
150
Adt
Jan-11 Dec-14 Fin-Ceramica
Faenza Spa
36
Adt
Jan-12 Dec-14 Singapore
General Hospital
Other Articular
Not yet
Cartilage Disorders;
Rec
Osteochondritis
Dissecans
232
Transplantation of Bone Marrow
Stem Cells Stimulated by Proteins
Scaffold to Heal Defects Articular
Cartilage of the Knee
NCT01159899
Peripheral Blood-drived Stem Cell
Trial on Damaged Knee Cartilage
RCT
NCT01076673
Evaluation of the CR Plug
(Allograft) for the Treatment of a
Cartilage Injury in the Knee.
study
NCT00793104
Treatment of Cartilage Lesions in
Flanders Today
RCT, efficacy study
NCT01421290
Assessment of Outcome of
Meniscus Repair With or Without
Platelet Rich Plasma
NCT00961597
Comparison of Microfracture
Treatment and CARTIPATCH®
Chondrocyte Graft Treatment in
Femoral Condyle Lesions
NCT00945399
Procedure:
Transplantation of
Bone Marrow Stem
Cells Activated in
Knee Arthrosis
Osteoarthritis; Knee
Arthrosis;
Osteochondral
Defects;
Osteochondritis
Dissecans;
Osteonecrosis
Genetic: Peripheral Damaged Articular
Blood derived Stem Cartilage
Cell and Hyaluronic
Acid; Genetic:
Hyaluronic Acid
Procedure:
Knee Injury
Placement of
allograft CR Plug in
primary injury site
Rec
50
Adt
Sen
Active,
NR
50
Adt Nov-09 Apr-12 Kuala Lumpur
Sports Medicine
Centre
Active,
NR
20
Adt Nov-08 Mar-12 RTI Biologics
Sen
Procedure: Surgery; Lesion of Joint
Other: Conservative Capsule of Knee
comparator
Region
Not yet
Rec
40
Adt Mar-12 Mar-12 University
Hospital, Ghent
Procedure: Meniscus Cartilage Disease
repair for red/white
tears without PRP;
Procedure: Meniscus
repair with PRP
Procedure:
Knee Chondral;
Microfracture;
Osteochondral
Procedure:
Defect
autologous
chondrocyte
implantation
(CARTIPATCH®
procedure)
Invite
25
Rec
64
Child Sep-09 Dec-11 Cincinnati
Adt
Sportsmedicine
Sen
Research and
Education
Foundation
Adt Oct-08 Dec-11 TBF Genie
Tissulaire
233
Jul-10 Jun-12 University of
Marseille
Study to Compare the Efficacy and Procedure:
Cartilage Injury;
Safety of Cartistem® and
Microfracture
Osteoarthritis
Microfracture in Patients With
treatment; Biological:
Knee Articular Cartilage Injury or Cartistem
Defect
study
NCT01041001
RCT of ChondroCelect® (in an ACI Procedure:
Articular Cartilage
Procedure) vs Microfracture in the Microfracture; Drug: Lesion of the
Repair of Cartilage Defects of the ChondroCelect
Femoral Condyle
Knee
implantation
study
NCT00414700
Rec
104
Adt Feb-09 May-11 Medipost Co Ltd. http://ClinicalTrials.gov/show/NCT01041001
Sen
Comp
118
Adt Feb-02 Jan-10 TiGenix n.v.
Other: DeNovo NT, Degenerative Lesion Rec
Natural Tissue Graft of Articular Cartilage
of Knee;
Osteochondritis
Dissecans
Clinical Application of BioCleanse Other: BioCleanse Damaged Meniscus Active,
Meniscus
Meniscus
NR
NCT00659880
Novel One-step Repair of Knee
Other: No PRF
Meniscal Injuries
Invite
Meniscal Tear Using Platelet-rich
Fibrin
Parallel assignment
NCT01211119
Resistance Exercise and Knee
Other: normal
Knee Osteoarthritis
Rec
Osteoarthritis Pain, Functional
activities and clinical
Impairment and Cartilage Turnover care; Other:
RCT, efficacy study
Concentric Focused
NCT01245283
Resistance Exercise;
Other: Eccentric
Focused Resistance
Exercise
400
Adt Feb-11 Sep-18 Zimmer
Sen
Orthobiologics,
Inc.
10
Adt Apr-08 Sep-13 RTI Biologics
Sen
18
Adt
90
Sen
Florida
Other
DeNovo NT Longitudinal Data
Collection (LDC) Knee Study
Cohort study
NCT01329445
234
Jan-11 Dec-13 Taipei Medical
University
WanFang
Hospital
Autologous Mesenchymal Stem
Cells vs. Chondrocytes for the
Repair of Chondral Knee Defects
study
NCT01399749
Other: Implantation
of autologous cells
Follow-Up Trial Comparing BSTCarGel and Microfracture in Repair
of Articular Cartilage Lesions in the
Knee
NCT01246895
Chondrocyte Maturation and
Cartilage Loss Following Meniscal
Injury
NCT00595803
Effects of Osteotomies Around the
Knee on Cartilage
Glycosaminoglycan Content Using
dGEMRIC Non-invasive Imaging
NCT01269944
Articular Cartilage
Lesion of the
Femoral Condyle
Articular Cartilage
Lesions of the Knee
Meniscal Tear
Not yet
Rec
30
Adt Sep-11 Jun-12 Fundacion para http://ClinicalTrials.gov/show/NCT01399749
la Investigacion
Biomedica del
Hospital
Universitario la
Paz
Rec
80
Adt Dec-10 Mar-14 Piramal
Healthcare
Canada Ltd
Active,
NR
42
Rochester;
National
Institutes of
Health;
VirtualScopics,
Inc.
Adt Jul-07 Feb-11 UMC Utrecht;
Sen
Orthopaedics
department,
University
Medical Center
Utrecht
Medial Compartment Active,
Osteoarthritis of the NR
Knee
10
Conditions
Recruit
n
Rec
100
A9F: ARTHROPLASTY
Title
Interventions
CT ID
Behavioural
Adding Value in Knee Arthroplasty Behavioral: Care
Post-total Knee Replacement
Navigator
(TKR) Care Navigator Trial
RCT, efficacy
studyNCT01540851
Osteoarthritis;
Degenerative Joint
Disease
235
Age Start
(Grp) Date
Adt
Sen
End Sponsors
Date
Jul-11 Sep-13 Brigham and
Women's
Hospital
URL
Weight Loss Intervention Before Behavioral: 8 weeks Osteoarthritis, Knee;
Total Knee Replacement
weight loss program, Obesity
RCT, efficacy study
Cambridge.
NCT01469403
Guided Imagery Response in Total Behavioral: GUIDED Osteoarthritis
Knee Replacement
IMAGERY;
Behavioral:
NCT01491750
PLACEBO
Rec
102
Rec
82
Pre-operative Rehabilitation
Exercise Program for Total Knee
Arthroplasty
RCT, efficacy study
NCT00493142
Behavioral: Exercise Osteoarthritis;
Rec
Comparison of Ways to Prepare
Patients for Decisions About Joint
Replacement Surgery
Phase III: RCT
NCT00911638
Behavioral: Patient
decision aid and
referral onward.;
Behavioral: Patient
education and
referral onward
Behavioral: Exercise
Osteoarthritis;
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Active,
NR
Osteoarthritis, Knee
Comp
38
Adt Sep-09 Dec-11 Helen Hays
Sen
Hospital
Behavioral: Nurse
dispensed oral
morphine.;
Behavioral: Patient
self medication of
oral morphine.
Arthroplasty, Knee
Replacement; Pain
Control
Rec
144
Adt Oct-10 Jun-11 The Royal
Sen
Bournemouth
Hospital; Royal
Bournemouth
and Christchurch
Hospitals NHS
Foundation Trust
A Comparative Analysis of Two
Types of Exercise on Outcomes
Following Total Knee Arthroplasty
RCT, efficacy study
NCT01545986
Self Medication With Oral
Morphine After Total Knee
Arthroplasty.
NCT01226186
Sen
Aarhus
Adt Jun-11 Jan-13 Kent State
Sen
University;
National Center
for
Complementary
and Alternative
Medicine
(NCCAM)
230 Adt Jul-08 Dec-12 University of
Sen
Alberta; Alberta
Heritage
Foundation for
Medical
Research;
Canadian
Institutes of
Health Research
340 Child May-08 Jan-12 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00911638
Adt
Research
Sen
Institute
(Canada)
236
Perioperative Intervention to
Improve Post-TKR Support and
Function
NCT00566826
Device
A Study to Determine the
Performance of the Press Fit
Condylar (P.F.C.) Sigma RP-F
Knee System
study
NCT00761410
A Prospective, Randomized Study
Comparing Cemented and
Cementless Total Knee
Replacement
RCT
NCT01194817
Gender Solutions Natural Knee
Post-Market Study
NCT01463566
LPS Flex Porous Femoral
Components
NCT01462240
Behavioral: Patient
support sessions;
Behavioral:
Treatment as usual
Osteoarthritis;
Arthroplasty,
Replacement, Knee
Device: P.F.C.
Sigma RP-F Total
Knee Replacement
Osteoarthritis
Rec
180
Adt Jun-08 Jun-11 National Institute http://ClinicalTrials.gov/show/NCT00566826
Sen
of Arthritis and
Musculoskeletal
and Skin
Diseases
Active,
NR
150
Adt Oct-04 Jan-29 DePuy
Sen
International
Device: High-Flexion Knee Osteoarthritis
Invite 100 Child Apr-10 Dec-26
Knee Replacement
Adt
System using
Sen
Cemented Fixation;
Device: High-Flexion
Knee Replacement
System using
Cementless Fixation
Device: Zimmer
Osteoarthritis;
Not yet 300 Adt Jan-12 Jan-25
Gender(R)
Inflammatory
Rec
Sen
Solutions(TM)
Arthritis; PostNatural-Knee(R) Flex traumatic Arthritis;
System
Osteonecrosis;
Varus or Valgus
Deformities
Device: LPS Flex
Osteoarthritis;
Not yet 300 Adt Dec-11 Dec-24
Porous Femoral
Rheumatoid Arthritis; Rec
Sen
Components
Poly Arthritis;
Collagen Disorders;
Avascular Necrosis
of Femoral Condyle;
TKA
237
Anderson
Orthopaedic
Research
Institute;
Zimmer, Inc.
Zimmer, Inc.
Zimmer, Inc.
Survivorship of the Press Fit
Condylar (P.F.C.) Sigma Fixed
Bearing Knee With a Cobalt
Chrome Tibial Tray
study
NCT00734019
A Prospective, Clinical
Investigation of the Vanguard 360
Revision Knee
study
NCT01542580
The Press Fit Condylar (P.F.C.)
Sigma Rotating Platform (RP) TC3
Revision Knee in Revision Knee
Arthroplasty
study
NCT00733681
Patello-Femoral Joint Post Market
Clinical Follow-up Within the Knee
Registry
NCT01469806
Long-Term Study of the DePuy
Low Contact Stress (LCS)
Complete Total Knee System
NCT00733915
Sigma CR150 Versus Sigma CR
Knee RCT
NCT01418378
Device: P.F.C.
Sigma Knee
Knee Osteoarthritis
700
Adt Oct-05 Oct-24 DePuy
Sen
International
Device: VANGUARD Osteoarthritis
360
Not yet 255
Rec
Adt Mar-12 Apr-24 Biomet, Inc.
Sen
Device: PFC Sigma Osteoarthritis
RP TC3 Revision
knee system
Active,
NR
181
Sen
International
Device: Zimmer
Primary Partial Knee Not yet 120
Gender Solutions
Arthroplasty;
Rec
PFJ Knee Prosthesis Patellofemoral Joint
Adt Nov-11 Oct-23 Zimmer, Inc.
Sen
250 Child Jan-02 Dec-22 DePuy
Adt
International
Sen
170
Device: L.C.S.
Arthroplasty,
Complete Knee
Replacement, Knee
(DePuy Low Contact
Stress Complete
Knee System)
Device: Sigma
CR150; Device:
Sigma CR
Osteoarthritis
Active,
NR
Active,
NR
Rec
238
Adt
Sen
Jul-11 Sep-22 DePuy
International
PFC Sigma Fixed and Mobile
Knee Study
study
NCT00208325
Study of Knee Replacements for
Patellofemoral Osteoarthritis
study
NCT01326156
Signature Personalised Patient
Care System With the Vanguard
Knee System Study
RCT
NCT01092312
Device: P.F.C Sigma Osteoarthritis, Knee
Fixed Bearing total
knee system; Device:
P.F.C Sigma RP
Mobile Bearing knee
system
Device: Knee
arthroplasty
Device: Vanguard
Knee System with
Signature Knee
Guide; Device:
Vanguard Knee
System with
conventional
Instruments
Postmarketing Study for Determine Device: SIGMA HP
Performance of the SIGMA HP® PARTIAL KNEE
PARTIAL KNEE SYSTEM
NCT01529099
Comparison of haptic assisted
MAKOplasty®
versus non-assisted uniunicondylar knee
compartmental knee arthroplasty arthroplasty;
RCT, efficacy study
OXFORD® Partial
ISRCTN77119437
Knee Arthroplasty
Post-Market Study of the EPIK
Device: EPIK™ uniKnee System
compartmental knee
NCT01464632
Triathlon® PKR Outcomes Study Device: Triathlon
PKR
NCT00966979
Active,
NR
684
Adt May-99 Jul-22 DePuy
Sen
International
Rec
100
Sen
Aarhus; Stryker
Nordic; DePuy
Orthopaedics
Arthroplasty,
Replacement, Knee
Rec
628
Adt Mar-10 May-22 Biomet, Inc.
Sen
Gout; Pseudo-gout
Rec
200
Adt Nov-11 Apr-22 DePuy
Sen
International
Early-mid stage
osteoarthritis of the
knee
Active
150
Adt Apr-10 Oct-21 NHS Greater
Sen
Glasgow and
Clyde (UK)
Osteoarthritis; Post
Traumatic
Degenerative
Disease
Osteoarthritis; Post
Traumatic Arthritis
Rec
100
Adt Nov-11 Dec-20 Encore Medical, http://ClinicalTrials.gov/show/NCT01464632
L.P.
Rec
184
Adt Dec-09 Dec-20 Stryker
Sen
Orthopaedics
239
Device: LCS
Osteoarthritis
Difference in Low Contact Stress Complete Duofix;
(LCS) Duofix Versus Low Contact Device: 2 - LCS
Stress (LCS) Porocoat Knee
Complete Porocoat
Systems
study
NCT00733499
Comparing X-3 To N2vac
Device: X-3
Osteoarthritis
Polyethylene With the Triathlon
polyethylene; Device:
Total Knee System
N2Vac polethylene
Phase IV: RCT
NCT00665964
Functional outcome of the P.F.C. P.F.C.®Sigma RP-F Osteoarthritis of the
Sigma® RP-F knee system and
knee system;
knee
the P.F.C. Sigma® knee system: A P.F.C.®Sigma knee
prospective, randomised controlled system
trial
RCT
ISRCTN64287972
Post-Market Study of the
Device: 3DKnee™ Degenerative Joint
3DKnee™ System
System
Disease;
Osteoarthritis;
study
NCT00819481
Traumatic Arthritis
Device: Oxford®
Osteoarthritis;
Oxford® Meniscal
Meniscal
Avascular Necrosis
Unicompartmental Knee System Unicompartmental
Knee System
NCT00578994
Prophecy Guide Outcomes in Total Device: Prophecy
Knee Replacement Surgery
Technique; Device: Knee; Total Knee
Phase IV: RCT, bio-equivalence Navigation System Replacement
study)
NCT01163708
Total Knee Replacement Using
Device: Simplex®
Osteoarthritis;
Simplex® or Cobalt™ Bone
Bone Cement;
Cement
Device: Cobalt™
Bone Cement
Knee Arthritis
NCT00589485
Active,
NR
204
Adt Jun-07 Nov-20 DePuy
Sen
International
Wdrwn 384
Adt May-08 May-20 Dalhousie
Sen
University;
Stryker Canada
LP
Active
84
Adt Mar-08 Mar-19 South Tees
Sen
Hospitals NHS
Trust (UK)
Active,
NR
300
Adt Feb-09 Dec-17 Encore Medical, http://ClinicalTrials.gov/show/NCT00819481
Sen
L.P.
Active,
NR
388
Adt Mar-06 Dec-17 Biomet
Sen
Orthopedics,
LLC
Not yet 188
Rec
Term
100
240
Adt Aug-10 Dec-17 Global
Sen
Orthopaedic
Technology;
LSS Surgical Pty
Ltd
Adt Nov-06 Nov-17 Biomet, Inc.;
Sen
Lexington Clinic
Oxford Partial Knee Replacement.
A Randomized Clinical Trial of
Three Implant Types
NCT00679120
Device: Oxford Uni Osteoarthritis, Knee
Knee; Device: Oxford
Uni Knee; Device:
Oxford Uni Knee
I-beam and Cruciate Tibial
Components Used in Total Knee
Replacement
NCT00588783
Triathlon Total Stabilizer (TS)
Outcomes Study
NCT00958789
Prospective Multicenter Post
Approval Study of the LPS-Flex
Mobile Bearing Knee
RCT, safety study
NCT00854295
Device: I-beam
design; Device:
Cruciate design
Clinical Outcomes and Costeffectiveness Analysis of
ShapeMatch Technology
NCT01483066
Scorpio Cruciate Retaining (CR)
Outcomes Study
NCT00965146
Serum Metal Ion Concentration
After Total Knee Arthroplasty
(TKA)
RCT
NCT00862511
Biomechanics of Gait Pattern
Adaptation in Patients After Total
Knee Arthroplasty
RCT
NCT01412814
Device: Triathlon
Total Stabilizer
Rec
75
Degenerative
Term
Arthritis;
Osteoarthritis;
Knee Arthritis
Arthroplasty,
Rec
Replacement, Knee
100
Device: NexGen
LPS-Flex Mobile
Bearing Knee
Osteoarthritis;
Avascular Necrosis
of the Femoral
Condyle; Moderate
Varus; Valgus;
Flexion Deformities
Device: ShapeMatch Total Knee
Technology
Arthroplasty
Rec
181
Adt May-09 Oct-17 University of
Sen
Aarhus; Aarhus
University
Hospital; Vejle
Hospital; Biomet,
Inc.
Adt Aug-06 Sep-17 Biomet
Sen
Orthopedics,
LLC; Lexington
Clinic
Adt
Sen
Jul-09
Jul-17 Stryker
Orthopaedics
400 Child Apr-09 Dec-16 Zimmer, Inc.
Adt
Sen
Not yet 150
Rec
Adt Feb-12 Sep-16 Lauren Beaupre; http://ClinicalTrials.gov/show/NCT01483066
Sen
Stryker Canada
LP
Device: Scorpio®
Cruciate Retaining
(CR) Total Knee
System
Device: Total Knee
Arthroplasty (TKA)
Arthroplasty,
Replacement, Knee
Term
228
Adt Jun-01 Jun-16 Stryker
Sen
Orthopaedics
Osteoarthritis; Metal
Ion Levels
Rec
120 Child Mar-09 Dec-15 Dresden
Adt
University of
Sen
Technology;
Aesculap AG
Device:
AposTherapy
Biomechanical
System; Other:
Physical Therapy
Program
Knee Arthroplasty;
Knee Arthritis
Osteoarthritis;
Osteoarthritis;
Musculoskeletal
Diseases
Rec
60
241
Adt
Sen
Jul-11 Sep-15 Tel-Aviv
Sourasky
Medical Center
A Study to Compare the Press Fit
Condylar (P.F.C.) Sigma Rotatingplatform High-flexion (RP-F)
Versus The Press Fit Condylar
(P.F.C.) Sigma Rotating-platform
(RP) Knee Implants
study
NCT00733369
A Study to Evaluate the DePuy
Minimally Invasive
Unicompartmental Knee
study
NCT00734084
A Study to Evaluate the
Performance of the DePuy Low
Contact Stress (LCS®) Complete
Anterior-Posterior Glide (APG)
Mobile Bearing Knee
study
NCT00733486
A prospective imaging study of
cruciate retaining and substituting
knee replacement, in osteoarthritis
and healthy aging - the PICKLeS
study
RCT, efficacy study
ISRCTN75076749
Triathlon Posteriorly Stabilized
(PS) Total Knee System Outcomes Study
assignment
NCT00957021
Device: PFC Sigma Knee Osteoarthritis
RPF; Device: PFC
Sigma RP
Active,
NR
106
Adt Nov-07 Aug-15 DePuy
Sen
International
Device: Preservation Osteoarthritis
Unicompartmental
Knee
Active,
NR
120
Adt Apr-02 Jun-15 DePuy
Sen
International
Device: L.C.S. APG Osteoarthritis
Knee Anterior
Posterior Glide knee
Active,
NR
300
Adt Aug-05 Jan-15 DePuy
Sen
International
Rotating bearing
knee, retaining the
posterior cruciate
ligament; Posterior
stabilised knee that
sacrifices the
posterior cruciate
ligament.
Device: Triathlon
Posterior Stabilized
(PS) Total Knee
System; Device:
Triathlon Posterior
Stabilized (PS) Total
Knee System
Knee osteoarthritis,
awaiting total knee
replacement;
Healthy agematched; Healthy
Active
120
Adt Jan-12 Dec-14 Canberra
Sen
Hospital
(Australia)
Arthroplasty,
Replacement, Knee
Active,
NR
502
Adt Dec-05 Dec-14 Stryker
Sen
Orthopaedics
242
Long-term Study of The Press Fit Device: P.F.C.
Knee Osteoarthritis
Condylar (P.F.C.) Sigma Total
Sigma Total Knee
Knee Replacement System
System
study
NCT00734110
Multi-center, Non-comparative
Device: Total Knee Noninflammatory
Study of Primary Total Knee
Replacement
Degenerative Joint
Arthroplasty (TKA) Functional
Disease
Performance
study
NCT01497730
Roentgen Stereophotogrammetric Device: Trabecular Osteoarthritis
Analysis (RSA) Trial Comparing
Metal Modular Tibial
Trabecular Metal Monoblock and Total Knee
Modular Tibial Components
Component
study
NCT01180595
The Fixed Bearing Lateral
Fixed Bearing Lateral Osteoarthritis or
Stabilised DJO 3D Knee™ versus Stabilised DJO 3D rheumatoid arthritis
the Finsbury Medial Rotation
Knee™; Finsbury
affecting the knee
Knee™ System versus the Stryker Medial Rotation
Triathlon® knee in primary total
Knee™ System;
knee replacement for osteoarthritis Stryker Triathlon®
and rheumatoid arthritis
knee
RCT, efficacy study
ISRCTN60834248
Signature Versus Computer
Device: Signature
Joint Disease
Assisted Surgery Study
Custom Cutting
Guides; Other:
assignment
Computer Assisted
NCT01256216
Surgery
Randomized Trial to Compare
Device: Total Knee Osteoarthritis of the
Axial Alignment in TKA With Use Arthroplasty
Knee
of Standard Instruments or
Visionaire Cutting Block System.
study
NCT01224522
Active,
NR
731 Child Oct-00 Oct-14 DePuy
Adt
International
Sen
Rec
840
Adt Oct-11 Oct-14 DePuy
Sen
Orthopaedics
Rec
50
Adt Feb-11 Sep-14 Dalhousie
Sen
University;
Zimmer, Inc.
Actve
90
Adt Aug-11 Jul-14 Joint
UCL/UCLH/Roy trials.com/ISRCTN60834248
al Free
Biomedical
Research Unit
(UK)
Invite
306
Adt Sep-10 Dec-13 Biomet, Inc.
Sen
Rec
70
Adt Mar-11 Jul-13 Smith & Nephew http://ClinicalTrials.gov/show/NCT01224522
Sen
Orthopaedics
AG
243
The Efficacy and Cost Analysis of Device: Hemovac
Total Joint
Rec
Arthroplasty; Hip,
Reinfusion Drains Versus
drain; Device:
Knee
Tranexamic Acid in Total Joint
OrthoPAT drain;
Arthroplasty
Drug: Tranexamic
acid
NCT01514474
A Comparison Between Signature Device: Signature
Arthroplasty,
Rec
Personalised Patient Care to
Knee Guide; Device: Replacement, Knee
Conventional Total Knee
Conventional
Arthroplasty (TKA) and Computer Instrumentation;
Assisted Navigation
Device: Computer
Assisted Navigation
NCT01145157
Roentgen Stereophotogrammetric Device: Triathlon
Osteoarthritis, Knee Active,
Analysis (RSA) and Dual Energy Periapatite (PA)NR
X-ray Absorptiometry (DEXA) to
coated Tibial
Evaluate Fixation of Periapatite
Component
Coated Triathlon Total Knee
Arthroplasty (TKA) Components
NCT01180582
Compare the Effects of a Standard Device: Kneehab XP; Total Knee
Not yet
Therapy Protocol With a 12-week Device: quadriceps Replacement
Rec
Peri-Operative Program of
TENS (at a minimal
Kneehab XP Neuromuscular
sensory input) using
Electrical Stimulation Compared to Kneehab XP
a Control Treatment in Patients
Undergoing Total Knee
Replacement
NCT01548040
Roentgen Stereophotogrammetric Device: Advance
Osteoarthritis
Active,
Analysis (RSA) to Evaluate
Biofoam porous
NR
Fixation of Biofoam Advance Total metal backed tibial
Knee Arthroplasty Components
component with or
without screw
NCT00657956
augmentation
Long Term Foundation Knee Study Device: cruciateTotal Knee
Invite
retaining Foundation Replacement
NCT01274546
Knee system
234
Adt Jan-12 Jun-13 OrthoCarolina
Sen
Research
Institute, Inc.
150
Adt
Sen
30
Adt Apr-09 Apr-13 Dalhousie
Sen
University;
Stryker
Orthopaedics;
Capital District
Health Authority,
Canada
118
Adt Mar-12 Mar-13 Bio-Medical
Sen
Research, Ltd.
50
Adt Apr-08 Jan-13 Dalhousie
Sen
University;
Wright Medical
Technology
Jul-10 Jun-13 Biomet, Inc.
450 Child Aug-10 Jan-13 Encore Medical, http://ClinicalTrials.gov/show/NCT01274546
Adt
L.P.
Sen
244
Functional Performance of the
Device: Total Knee Knee Arthroplasty
Journey Deuce Bicompartmental Replacement;
Versus the Genesis II Total Knee Device: Deuce
System
study
NCT01140815
Oxford Partial Knee Kinematics
Device: Oxford
Medial Knee
Gait Analysis Study
Partial Knee
Compartment
Arthritis
NCT01454908
Oxford® Partial Knee Kinematics Device: Oxford®
Medial Compartment
Gait Analysis Study
Partial Knee
Arthritis
NCT00576966
A Prospective, Randomized,
Device: The Zimmer Total Knee
Controlled Study Comparing Three NexGen Legacy
Arthroplasty
Tibial Component Designs in Total Knee System,
Knee Arthoplasty
modular cemented
tibia; Device: The
NCT00589147
Zimmer NexGen
Legacy Knee
System, non-modular
cemented tibia.;
Device: The Zimmer
NexGen Legacy
Knee System, nonmodular uncemented
tibia
Investigator Initiated Depuy
PFC sigma and
Knee replacement
Replacement knee In-Vivo
CR150 implants
Evaluation Study
RCT, efficacy study
ISRCTN26541777
Prospective Data Collection on
Device: Cementless Arthroplasty,
Cementless Oxford Partial Knee Oxford Partial Knee Replacement, Knee
NCT00760188
Comparative Outcomes
Device: Otto Bock C- Amputation
Assessment of the C-Leg With a Leg; Device: Otto
New Knee Prosthesis
Bock Genium
NCT01473992
Active,
NR
50
Adt Sep-07 Jan-13 Anderson
Orthopaedic
Research
Institute; Smith &
Nephew, Inc.
Active,
NR
18
Adt Apr-06 Dec-12 The CORE
Sen
Institute
Susp
18
Adt Apr-06 Dec-12 The CORE
Sen
Institute; Biomet,
Inc.
Active,
NR
408
Adt Aug-03 Dec-12 Mayo Clinic;
Sen
Zimmer, Inc.
Active
40
Adt Nov-10 Sep-12 University of
Sen
Leeds (UK)
Wdrwn
0
Adt
Sen
Jul-04 Sep-12 Biomet, Inc.
Rec
25
Adt
Jan-11 Jul-12 University of
South Florida;
Otto Bock
Healthcare;
State of Florida
245
Rehabilitation After Total Knee
Device: P.F.C.
Arthroplasty (TKA) - PFC Rotating Sigma knee
Versus Fixed Bearing
arthroplasty
RCT
NCT01150929
Osteoarthritis
Knee Arthroplasty Performed With Device: Customized
Conventional and Customized
Patient
Instrumentation
Instrumentation;
Phase IV: RCT
Device: Traditional
NCT01124305
Instrumentation
Use of Pulsed Electromagnetic
Device: Active
Fields for Postoperative Knee Pain Device (Torino II);
Device: Sham
NCT01415856
Device (Torino II)
Effect of TENS for Pain and
Device: Placebo
Function After Total Knee
TENS; Device:
Replacement
Intense TENS (EMPI
RCT, efficacy study
Select TENS)
NCT01364870
Impact of Noninvasive Targeted
Device: Ivivi Torino
Pulsed Electromagnetic Field
II; Device: Ivivi
(tPEMF) on Opioid Use, Pain, and Torino II
Joint Function Following Total
Knee Arthroplasty
NCT01475604
Knee Arthroplasty Registry
Device: any knee
joint arthroplasty
NCT01132365
device
Knee Arthroplasty
Uniglide™ Mobile Bearing
Unicondylar Knee System vs the
Uniglide™ Fixed Bearing
Unicondylar Knee System
study
NCT00740376
Rec
50
Active,
NR
52
Osteoarthritis
Rec
40
Unilateral Primary
Osteoarthritis of
Knee; Primary
Osteoarthritis of
Knee Nos
Rec
340
Rec
100
Invite
Device: Uniglide
Osteoarthritis
Mobile Bearing
Unicondylar Knee
System; Device:
Uniglide Fixed
Bearing Unicondylar
Knee System
Rec
Adt Mar-07 Jul-12 University of
Sen
Aarhus;
Regionshospital
et Silkeborg;
Gigtforeningen;
Protesekompagniet
Child May-10 Jun-12 Anderson
Adt
Orthopaedic
Sen
Research
Institute
Adt Oct-10 May-12 Center for Joint http://ClinicalTrials.gov/show/NCT01415856
Sen
Surgery and
Sports Medicine,
Maryland
Sen
Iowa
Adt Nov-11 Apr-12 Amp
Sen
Orthopedics, Inc.
3156 Adt Apr-05 Feb-12 Heekin
Sen
Orthopedic
Research
Institute; DePuy
Orthopaedics;
Stryker
Orthopaedics;
ConforMIS, Inc.
420 Adt Aug-08 Feb-12 Corin
Sen
246
Use of Cold and Compression
Therapy With Total Knee
Replacement Patients
NCT00712816
Computer-Assisted Total Knee
Arthroplasty (TKA) With Zimmer
LPS Flex Knee System
Phase IV: RCT
NCT00300326
Optetrak Posterior Stabilized
Versus Optetrak Hi-Flex
Phase IV: Non-randomised,
parallel assignment, efficacy
study
NCT00808613
Device: Game Ready Osteoarthritis; Total
Injury Treatment
Knee Arthroplasty
System
(CoolSystems Inc.);
Other: Ice with
compressive
bandages
Device: LPS Flex
Total Knee
knee system
Arthroplasty for
Knee Osteoarthritis
Rec
224
Wdrwn
7
Adt Jan-06 Jan-12 Queen's
Sen
University;
Zimmer, Inc.
Device: Optetrak PS; Total Knee
Susp
Device: Optetrak Hi- Replacement Due to
Flex
Osteoarthritis,
Osteonecrosis,
Rheumatoid; Arthritis
and/or Posttraumatic
Degenerative
Problems
Device: Standard
Arthroplasty,
Active,
cutting guide for
Replacement, Knee
NR
TKA; Device:
Otismed MRI
generated cutting
guide for TKA
Device: Total knee Osteoarthritis
Comp
arthroplasty
90
Adt Dec-08 Jan-12 Exactech
Sen
120
Adt Jan-08 Jan-12 Department of http://ClinicalTrials.gov/show/NCT00837772
Sen
Veterans Affairs
80
Adt Jan-06 Jan-12 Heekin
Sen
Orthopedic
Research
Institute; Stryker
Orthopaedics
35
Adt Nov-11 Dec-11 BioPoly LLC
Sen
Total Knee Replacement Study
Using Standard Cutting Guide vs
Otismed MRI Generated Cutting
Guide
NCT00837772
Midvastus Versus Medial
Parapatellar Approach for
Minimally Invasive Total Knee
Arthroplasty
RCT, efficacy study
NCT01132378
BioPoly RS Knee Registry Study Device: BioPoly RS
for Cartilage Defect Replacement Partial Resurfacing
Knee Implant
efficacy study
NCT01473199
Cartilage Injury;
Defect of Articular
Cartilage; Cartilage
Damage
Rec
247
Adt
Sen
Jul-08 Jan-12 CoolSystems,
Inc.
Computer-Assisted Total Knee
Replacement Kinematics: DePuy
Sigma Posterior Cruciate
Substituting Knee and the DePuy
Sigma RP Rotating Platform Knee
NCT00375856
Evaluation of Orthopedic Knee
Measurement Using Lunar iDXA
NCT01348958
Comparison of High Flex and
Standard Rotating Platform Total
Knee Arthroplasty (TKA)
RCT
NCT01176292
Device: DePuy
P.F.C.® Sigma
Rotating Platform
Knee
Device: iDXA knee
software
Device: Rotating
Platform High-Flex
Cruciate Substituting
TKA; Device:
Rotating Platform
TKA
PEAK PlasmaBlade 4.0 Versus
Device: PEAK
Traditional Electrosurgery in Total PlasmaBlade 4.0;
Knee Replacement.
Device: Traditional
RCT
Electrosurgery with
NCT01081886
scalpel
X-3 Polyethylene Survival
Device: Stryker X3
Outcomes Study
crosslink
NCT00493792
The Effectiveness of Antibiotic
Device: Simplex™ P
Cement (ABC) Compared to
with Tobramycin;
Regular Cement in Reducing the Device: Simplex™ P
Rate of Infection Following Total
Knee Arthroplasty: The ABC Trial
NCT01079559
Evaluation of the Safety and
Device: zirconia
Effectiveness of the Kinamed Gem femoral component;
Ceramic Femoral Component for Device: cobalt
chrome femoral
component
study
NCT00743717
Rec
140
Adt Oct-06 Dec-11 Queen's
Sen
University;
DePuy
Orthopaedics
Hemi Knee
Active,
Arthroplasty; Patello- NR
femoral
Osteoarthritis
40
Adt May-11 Dec-11 GE Healthcare
Sen
Knee Osteoarthritis
Active,
NR
142
Adt Aug-07 Dec-11 Anderson
Sen
Orthopaedic
Research
Institute; DePuy
Orthopaedics
Degenerative Joint
Disease;
Osteoarthritis; Total
Knee Arthroplasty
Term
40
Adt Nov-09 Nov-11 Peak Surgical,
Sen
Inc.
Arthroplasty,
Rec
572
Replacement, Knee;
Total Knee
Replacement
Infection;
Not yet 8800
Rec
Knee
Adt Feb-07 Sep-11 Mayo Clinic
Sen
Knee Osteoarthritis
Child Feb-04 Aug-11 Kinamed
Adt
Incorporated
Sen
Active,
NR
10
248
Adt
Sen
Jul-10 Aug-11 University of
Western Ontario,
Canada
Kneehab® pre and post total knee
replacement surgery
RCT
ISRCTN89785408
Kneehab® group: 6 Patients undergoing
weeks pre- & post- total knee
knee replacement
replacement
surgery (30 mins of surgery.
NMES twice a day
for 12 weeks) +
standard
physiotherapy.
Control group: 6
weeks pre & post
surgery standard
physiotherapy.
Do We Need High-Flexing Total
Device: legacy
Osteoarthritis
Knee Arthroplasty to Improve the posterior stabilized
Survivorship and to Decrease the high-flexion (NexGen
Incidence of Osteolysis?
LPS-Flex); Device:
legacy posterior
NCT01422642
stabilized standard
(NexGen LPS)
Comparison of A Mobile-Bearing Device: Sigma Knee Knee
Total Knee System With A Fixed- System; Device:
Bearing Total Knee System In
Sigma Pressfit
Cemented Total Knee Arthroplasty Condylar Posterior
RCT
NCT00589108
System; Device:
Sigma Pressfit
Condylar Posterior
System all
polyethylene tray
Comparison of Total Knee
Device: Zirconium
Osteoarthritis
Arthroplasties With Oxidized
(Zirconium Genesis
Zirconium and Cobalt Chromium II); Device: CobaltFemoral Components
Chrome (Cobalt
Chrome Genesis II)
NCT01336595
Long-Term Comparison of Fixed- Device: anatomic
Osteoarthritis
and Mobile-Bearing Total Knee
modular fixedArthroplasties (TKAs) in Patients bearing; Device: low
With OA â‰¤50 Years Old
contact stress
Phase IV: RCT
rotating platform
NCT01361152
mobile-bearing
Comp
200
Adt Apr-10 Jul-11 The Royal
Sen
Liverpool &
Broadgreen
University
Hospital (UK)
Comp
111
Adt Jan-01 Jun-11 Ewha Womans
Sen
University
Comp
240
Adt Jan-01 May-11 Mayo Clinic
Sen
Comp
331
Adt Jan-03 Apr-11 Ewha Womans
Sen
University
Comp
216
Adt
249
Apr-93 Mar-11 Ewha Womans
University
Total Knee Arthroplasty
Comparing Cementless to
Cemented Fixation
study
NCT01335438
A Study to Determine if Carbon
Dioxide Lavage During Total Knee
Surgery Reduces Intraoperative
Embolic Events
NCT00736125
Foundation Knee Study Retrospective
Phase IV: Retrospective, cohort
study
NCT00764894
Device: Cementless Osteoarthritis
(Nexgen); Device:
Cemented (Nexgen)
Comp
96
Adt Jan-97 Mar-11 Young Hoo Kim http://ClinicalTrials.gov/show/NCT01335438
Sen
Device: pulsatile
saline lavage;
Device: carbon
dioxide lavage
Postoperative
Complications;
Memory Disorders
Comp
40
Adt Dec-07 Mar-11 Kinamed
Sen
Incorporated;
Department of
Veterans Affairs
Device: Foundation
Knee
200
Adt Oct-07 Feb-11 Encore Medical, http://ClinicalTrials.gov/show/NCT00764894
Sen
L.P.
Clinical Investigation of the LCS®
Complete Posterior Stabilized
Mobile-bearing Total Knee System
study
NCT00487565
Use of Knotless Suture for Closure
of Total Hip and Knee
Arthroplasties
RCT, efficacy study
NCT00834483
Device: Total knee
arthroplasty
Osteoarthritis; Post- Term
Inflammatory Tissue
Disorders; Arthritis
Secondary to Other
Diseases; Avascular
Necrosis of the
Femoral Condyles
Osteoarthritis;
Comp
Post-traumatic
Arthritis; Juvenile
Arthritis
250
Adt Sep-06 Feb-11 DePuy
Sen
Orthopaedics
Primary Knee
Active,
Arthroplasty; Primary NR
Hip Arthroplasty
200
Adt Feb-09 Jan-11 Rush University http://ClinicalTrials.gov/show/NCT00834483
Sen
Medical Center
Arthroplasty,
Comp
Replacement, Knee;
Blood Transfusion,
Autologous; Blood
Transfusion
45
Adt Jan-09 Dec-10 Astra Tech AB
Sen
Device: Knotless
suture for wound
closure; Device:
Layered traditional
wound closure
(monocryl)
A Clinical Study to Investigate if
Device: Bellovac
Transfusion of Patients Own Shed ABT; Procedure:
Blood Improves the Immunological Allogenic Blood
Status in Comparison to
Transfusion
Transfusion of Donor Blood (“Bank
Blood”")"
NCT00839241
250
A Comparison of Fixation Method
in Total Knee Arthroplasty - Low
Viscosity Versus High Viscosity
Bone Cement
NCT00175162
NexGen Gender Fixed Bearing
Knee Versus NexGen Legacy
Knee Posterior Stabilized (LPS) Flex Fixed Bearing Knee: A Study
Comparing Two Different Knee
Prostheses
NCT00901329
A Study to Compare the NexGen
CR and CR-Flex Knee Implants
NCT00761956
A randomised controlled trial of
different knee prostheses
RCT
ISRCTN45837371
Device: Osteopal G Osteoarthritis
vs. RefobacinPalacos R bone
cement
Wdrwn
50
Sen Jun-07 Dec-10 University of
Aarhus; Aarhus
University
Hospital; Biomet,
Inc.
Device: NexGen
Total Knee
Gender Fixed
Arthroplasty
Bearing Knee
prosthesis; Device:
NexGen LPS-Flex
Fixed Bearing Knee
prosthesis
Invite
24
Adt May-07 Dec-10 Hvidovre
Sen
University
Hospital;
FZimmer, Inc.
only
Device: NexGen CR- Total Knee
Comp 400 Adt
Flex Fixed Bearing Arthroplasty;
Sen
Knee; Device:
Osteoarthritis
NexGen CR Knee
Metal versus nonPrimary knee
Comp 2450 Child
metal backing of the replacement surgery
Adt
tibial component;
Sen
Resurface the
patella;
Unicompartmental
versus total knee
arthroplasty; Mobile
versus fixed bearing
Comparing Fixed-bearing Versus Device: fixed-bearing Osteoarthritis
Comp 100 Child
Mobile-bearing Prosthesis in Total (P.F.C.® Sigma);
Adt
Knee Arthroplasty: A Prospective Device: mobileSen
Randomized Trial
bearing (P.F.C.®
Phase II: RCT
Sigma)
NCT01312532
The 3DKnee™ System: A PostDevice: 3DKnee
Osteoarthritis;
Comp 71
Adt
Market Study
Sen
Post Traumatic
assignment
Arthritis; Varus
NCT00764673
Deformity; Avascular
Necrosis
251
Sep-04 Dec-10 Zimmer, Inc.
Dec-98 Dec-10 Department of
Health (UK)
Jun-04 Nov-10 Isfahan
University of
Medical
Sciences
Oct-06 Oct-10 Encore Medical, http://ClinicalTrials.gov/show/NCT00764673
L.P.
Prevena™ Incision Management
System Over Primarily Closed Hip
and Knee Incisions in Patients
Immediately Post Total Hip and
Knee Arthroplasty
assignment
NCT01380665
Vanguard Knee Anterior Stabilized
Versus Posterior Stabilized
Bearing Study
RCT
NCT01308515
Device: Prevena
Linear or Emi-linear
Incisional
Incisions; Total Hip
Management System Arthroplasty; Total
Knee Arthroplasty
Device: Vanguard
Osteoarthritis;
Knee System with
Degenerative
AS Bearing; Device: Arthritis
Vanguard Knee
System with PS
Bearing
Device: mobileKnee Arthritis
bearing TKA; Device:
fixed- bearing TKA
Comparison Between FixedVersus Mobile-bearing TKA
RCT, efficacy study
NCT00435357
Evaluation of Triathlon - a New
Device: Triathlon
Total Knee
Total Knee Prosthesis System
Knee System
Arthroplasty
Phase IV: RCT
NCT00436982
Prospective Evaluation of Vitagel Device: Vitagel
Arthritis
for Reduction in Blood Loss and
Pain Following Unilateral Total
Knee Arthroplasty
NCT01027286
Dynamic Splinting After Total Knee Device: Knee
Reduced Knee
Arthroplasty
Extension Dynasplint Flexion
efficacy study
NCT00857701
Oxford Unicompartmental Knee
Device: Oxford
Knee Arthritis
Arthroplasty With and Without
Unicompartmental
Navigational Unit
Knee
NCT00862316
Term
100
Adt Oct-09 Oct-10 KCI USA, Inc.
Sen
Wdrwn
0
Adt Sep-10 Sep-10 Biomet, Inc.
Sen
Active,
NR
160
Adt Feb-07 Jul-10 Hospices Civils
Sen
de Lyon
Rec
420
Adt Dec-05 Jun-10 Stryker Nordic
Sen
Comp
108
Adt
Sen
Rec
50
Adt Jan-09 May-10 Dynasplint
Sen
Systems, Inc.
Comp
48
Child May-09 May-10 Biomet, Inc.;
Adt
Dartmouth
Sen
General Hospital
252
Jul-09 Jun-10 The Cleveland http://ClinicalTrials.gov/show/NCT01027286
Clinic; Orthovita
Unipolar vs. Bipolar Hemostasis in
Total Knee Arthroplasty: A
Prospective Randomized Trial
NCT01003080
Device: Aquamantys
Device; Other:
Standard of care
treatment for
hemostasis during a
total knee
arthroplasty.
A Study to Compare the NexGen Device: NexGen
LPS and LPS-Flex Knee Implants LPS-Flex Fixed
Bearing Knee;
NCT00763386
Device: NexGen
Legacy Posterior
Stabilized Knee
Comparing Clinical Outcome of 2 Device: Nexgen
Different Total Knee Prostheses: LPS-flex and AGC
Nexgen LPS-Flex Versus AGC
NCT00294528
Comparison of Nonposterior- and Device: PFC-Sigma
Posterior-Stabilized MobileRP; Device: LPS RP
Bearing Total Knee Arthroplasty
study
NCT01075620
Dietary supplements
Effect of Fish Oil on Surgery Pain
After Knee Replacement Patients:
Randomized, Prospective, Double
Blind, Placebo Control Trial
RCT, efficacy study
NCT01274910
10% Carbohydrate Drink for
Preventing Post-operative Nausea
and Vomiting (PONV) After Spinal
Morphine
study
NCT01301404
Dietary Supplement:
EPAX 6000 EE
1000mg (0.6 gr
DHA+EPA); Dietary
Supplement:
Capsules (Placebo)
Dietary Supplement:
10% carbohydrate
drink; Other: No
intervention
Knee Arthroplasty
Comp
111
Adt Aug-09 Apr-10 Montefiore
Sen
Medical Center
Total Knee
Arthroplasty;
Osteoarthritis
Comp
331
Adt Jun-01 Mar-10 Zimmer, Inc.
Sen
Rec
100
Sen
University
Hospital
Comp
126
Adt May-02 Jan-10 Ewha Womans
Sen
University
Rheumatoid Arthritis Not yet
Rec
60
Adt Jan-11 Mar-13 Rabin Medical
Sen
Center
Nausea and
Vomiting,
Postoperative; TKR
200
Adt Feb-11 Dec-12 Mahidol
Sen
University
Osteoarthritis
Rec
253
Analgesic Effect of Gabapentin in Drug: Gabapentin;
Total Knee Arthroplasty (TKA)
Drug: Gabapentin;
Phase IV: RCT, safety/efficacy Drug: Placebo
study
NCT01507363
Intravenous Ferric Carboxymaltose Drug: Ferinject 50
(Ferinject) in Patients Undergoing mg/ml; Drug: NaCl
Orthopaedic Surgery
0.9%
study
NCT01345968
Desflurane or Propofol Anesthesia Drug: propofol or
in Elderly Obese Patients
desflurane
Undergoing Total Knee
Replacement
Phase IV: RCT
NCT01270620
Rifampin Combination Therapy
Drug: RifampinVersus Monotherapy in Early
combination therapy;
Staphylococcal Infections After
Drug: Monotherapy
Total Hip and Knee Arthroplasty
NCT00423982
Safety of DAbigatran and
Drug: Dabigatran;
RIvaroxaban Versus NAdroparin in Drug: Rivaroxaban;
the Prevention of Venous
Drug: Nadroparin
Thromboembolism After Knee
NCT01431456
Drug: Gabapentin
Surgical Patients
study
NCT00221338
Analgesic Effect of Escitalopram in Drug: Escitalopram;
Drug: Placebo
NCT01430520
Postoperative Pain;
Postoperative
Sedation
Rec
300
Anemia; Knee
Replacement; Hip
Replacement
Rec
140
Obesity; Arthritis
Rec
100
Prosthesis-related
Infections;
Staphylococcal
Infections
Rec
100 Child Apr-06 Dec-14 Oslo University
Adt
Hospital
Sen
Venous
Thromboembolism
Not yet 150
Rec
Adt Jan-12 Dec-15 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Adt Jun-11 Oct-15 University
Sen
Hospital
Muenster; Vifor
Pharma
Adt Dec-10 Dec-14 Stanford
Sen
University;
Baxter
Healthcare
Corporation
Adt Oct-11 Oct-14 Martini Hospital http://ClinicalTrials.gov/show/NCT01431456
Sen
Groningen
Postoperative Pain;
spine, hip or knee
replacement.
Rec
312
Sen
California, San
Francisco
Postoperative Pain
Rec
120
Adt Sep-11 Dec-13 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
254
Duration of Leg Nerve Blocks With Drug:
Pain; Total Knee
Not yet 70
Dexamethasone Added to Local Dexamethasone;
Arthroplasty
Rec
Anesthetic
Drug: Ropivacaine
NCT01511211
Treatment of Patients Undergoing Drug: Dabigatran
Arthroplasty,
Rec
100
Primary Unilateral Elective Total etexilate
Replacement, Knee;
Knee or Hip Replacement With
Venous
Dabigatran Etexilate
Thromboembolism
Phase IV: RCT,
study
NCT01184989
Daptomycin Use for Antimicrobial Drug: Daptomycin; Staphylococcal
Rec
100
Prophylaxis in Methicillin Resistant Drug: Vancomycin Infections;
Staphylococcus Aureus (MRSA)
Colonized Adult Patients
Staphylococcus
Undergoing Primary Elective Hip
Aureus
or Knee Arthroplasty
NCT01196169
Study to Observe Safety of Xarelto Drug: Rivaroxaban Prophylaxis,
Not yet 500
in VTE Prophylaxis After Elective (Xarelto, BAY59Thromboembolism,
Rec
TKR or THR
7939)
Venous; Total Knee
Replacement; Total
NCT01523418
Hip Replacement
Does a Single Shot Femoral Nerve Drug: Femoral Nerve Post-operative Pain; Not yet 90
Block Alone Produce Appropriate Block; Drug:
TKA
Rec
Pain Relief?
Combined nerve
RCT
blocks; Drug:
NCT01303120
Patient-controlled
analgesia
Effect of Adductor-Canal-Blockade Drug: Ropivacaine; Pain After Total
Rec
50
on High Pain Responders After
Drug: Saline
Knee Arthroplasty
NCT01549704
Epsilon Aminocaproic Acid Vs.
Drug: Tranexamic
Osteoarthritis
Invite
54
Tranexamic Acid Vs. Placebo for Acid; Drug: Epsilon
Prevention of Blood Loss in Total Aminocaproic Acid;
Knee Arthroplasty
Drug: Normal Saline
NCT01527968
255
Adt Apr-12 May-13 University of
Sen
New Mexico
Adt Aug-10 Apr-13 Boehringer
Sen
Ingelheim
Pharmaceuticals
Adt Oct-10 Apr-13 Mountain Home http://ClinicalTrials.gov/show/NCT01196169
Sen
Research &
Education
Corporation;
East Tennessee
State University;
Cubist
Pharmaceuticals
Adt Jun-12 Apr-13 Bayer
Sen
Adt Mar-11 Mar-13 Hillel Yaffe
Sen
Medical Center
Adt Feb-12 Feb-13 University
Sen
Hospital,
Gentofte,
Copenhagen
Adt Jan-12 Jan-13 Heekin
Sen
Orthopedic
Research
Institute
Combination of Peripheral Nerve
Block and DepoDur in Total Knee
Joint Replacement
NCT00895531
Russian Non-Interventional Study
on Compliance of Venous
Thromboembolism (VTE)
NCT01444586
Effectiveness of Analgesia in Total
Knee Arthroplasty
NCT01304212
Drug: Depodur;
Procedure: sciatic
nerve block
Arthroplasty,
Replacement, Knee
Rec
120
Drug: Rivaroxaban
(Xarelto, BAY597939)
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Rec
2522 Adt Oct-11 Dec-12 Bayer
Sen
Drug: several drugs: Pain
morphine
chloride,ropivacaine,
epinephrine,ketorola
c; Drug:
ropivacaine,morphin
e
chloride,epinephrine,
ketorolac; Drug:
ropivacaine; Drug:
morphine ,ketorolac
ChloraPrep Versus Betadine for
Drug: Swab area
Arthroplasty, Knee
Elective Knee Replacement
with Betadine; Drug: Replacement;
Surgery
Swab area with
Replacement, Total
Phase IV: RCT, bio-equivalence ChloraPrep
Knee; Total Knee
study
Replacement
NCT01184196
Local Infiltration Analgesia During Drug: The injectant Pain
mixture consists of
RCT, efficacy study
150 mg
NCT01305733
levobupivacaine
mixed with 30 mg
ketorolac and 0.5 mg
adrenaline; Other:
saline injection
Analgesia After Total Knee
Drug: naropin; Drug: Total Knee
Replacement Surgery
marcaine; Drug:
Arthroplasty
RCT
sufentanil; Drug:
NCT01489631
neurontin
Not yet 156
Rec
Sen
Louisville; EKR
Therapeutics,
Inc
Sen Apr-11 Dec-12 Consorci
Sanitari de
Terrassa
Rec
200
Adt Nov-09 Dec-12 Central DuPage http://ClinicalTrials.gov/show/NCT01184196
Sen
Hospital
Rec
70
Adt Mar-11 Dec-12 Coxa, Hospital
Sen
for Joint
Replacement
Not yet
Rec
60
Adt Mar-12 Nov-12 St. Antonius
Sen
Hospital
256
Xarelto for VTE Prophylaxis After
Hip or Knee Arthroplasty
NCT00831714
Drug: Rivaroxaban Venous
(Xarelto, BAY59Thromboembolism
7939); Drug:
Standard care
treatment for VTE
prophylaxis
Drug: warfarin; Drug: Pulmonary
Fondaparinux:; Drug: Embolism
warfarin
Rec
Prophylaxis Against DVTs After
Active,
Primary Hip and Knee
NR
Replacement Surgery
NCT00767559
The Use of Evicel to Reduce Blood Drug: Evicel fibrin
Patients Age 20-90;
Rec
Loss in Total Knee Replacement sealant
Osteoarthritis
Surgery
NCT01235715
Fibrin Sealant in Bilateral
Drug: Fibrin sealant; Blood Loss
Rec
Simultaneous Total Knee
Drug: Saline water
Arthroplasty With Focus on Blood
Loss, Pain, Swelling and Strength
NCT01472913
Platelet Rich Plasma (PRP) in
Biological: Platelet Osteoarthritis;
Active,
Rich Plasma
Inflammatory
NR
Arthritis
NCT00826098
Can local anaesthetic injection
local infiltration
Undergoing total
Active
reduce pain in knee arthroplasty? analgesia; saline
knee replacement
RCT, efficacy study
surgery
ISRCTN35062232
Effect of Reversing Muscle
Drug: Sugammadex; Neuromuscular
Rec
Relaxation With Sugammadex
Drug: neostigmine Blockade;
Compared With Usual Care on
and glycopyrrolate or Arthroplasty,
Bleeding Risk in Patients on Blood atropine; Drug:
Replacement, Hip;
Thinners Undergoing Major Joint Placebo
Arthroplasty,
Surgery (P07038/MK-8616-059)
Replacement, Knee;
Blood Coagulation;
NCT01422304
Antithrombotic
Agents
1500 Adt Feb-09 Nov-12 Bayer
0
Sen
330
Adt Nov-08 Oct-12 The New
Sen
England Baptist
Hospital
200
Adt Sep-10 Sep-12 Hospital for
Sen
Special Surgery,
New York;
Ethicon, Inc.
48
Adt Aug-10 Aug-12 Hvidovre
Sen
University
Hospital
170 Child Dec-08 Jun-12 Exactech
Adt
Sen
44
Adt Oct-11 May-12 University
Sen
Hospitals of
Leicester (UK)
800
Adt Oct-11 May-12 Schering-Plough http://ClinicalTrials.gov/show/NCT01422304
Sen
257
Topical Tranexamic Acid and
Acute Blood Loss in Total Knee
Arthroplasty
study
NCT01370460
Effects of Pregabalin on Pain After
study
NCT01333956
Re-STOP DVT: Reload of High
Dose Atorvastatin for Preventing
Deep Vein Thrombosis in Statin
Users
study
NCT01063426
The Influence of the Femoral
Nerve Block on Quadriceps
Strength
RCT, efficacy study
NCT01111513
Drug: Tranexamic
Acute Blood Loss
Acid; Drug: Placebo Anemia;
Rec
100
Adt Jun-11 May-12 Henry Ford
Sen
Health System
Drug: Pregabalin
50mg; Drug:
Pregabalin 100mg;
Drug: Pregabalin
150mg; Drug:
Placebo
Drug: High dose
Atorvastatin+enoxap
arin; Drug:
Enoxaparin
Primary Total Knee
Arthroplasty
Rec
120
Adt May-11 Apr-12 Hospital for
Sen
Special Surgery,
New York
Thrombosis;
Prevention; Surgery;
TKA
Rec
180
Adt Nov-09 Mar-12 Hallym
Sen
University
Medical Center
Total Knee
Arthroplasty
Rec
135
Adt Nov-07 Feb-12 Hopital de
Sen
l'Enfant-Jesus;
Sanofi-Aventis
Analgesia
Rec
90
Adt Mar-09 Feb-12 University of
Sen
Manitoba
Drainage
Rec
600
Adt Mar-10 Dec-11 Rothman
Sen
Institute
Orthopaedics;
3M
Drug: 48-hour
ropivacaine
infusions; Drug:
Single dose
ropivacaine; Drug:
Patient controlled
analgesics
Drug: Periarticular
Arthroplasty
Injection; Drug:
CFNB + Posterior
NCT00869037
Capsular Injection
Evaluating the Effectiveness of 2 Drug: Duraprep
Surgical Skin Preparation Methods Surgical Solution
in Reducing Surgical Wound
Drainage After Total Hip or Knee
Replacement
RCT, efficacy study
NCT01097135
258
The Effects of Arixtra on Wound
Drainage Following Total Joint
Arthroplasty
study
NCT00909064
Effect of Oral Pregabalin on Spinal
Neurotransmitters in Patients
Undergoing Knee Replacement
Phase III: RCT, bio-equivalence
study
NCT00729690
Efficacy Study of Pre-emptive
Etoricoxib for Postoperative Pain
and Functional Outcome in Total
Knee Arthroplasty
NCT01246362
VTE Prevention After Elective
Surgery
NCT01153698
Comparison of Levobupivacaine
and Ropivacaine for Femoral
Neural Block
NCT01172197
A Comparison of Naropin and
Ketorolac for Postoperative
Arthroplasty
NCT00868348
Pain Control
study
NCT01041313
Drug: Fondaparinux Total Knee
Sodium (Arixtra)
Replacement
Not yet
Rec
91
Adt Jun-09 Dec-11 University of
Sen
California, Davis
Drug: Pregabalin;
Drug: Pregabalin;
Drug: Placebo
Active,
NR
48
Adt Aug-08 Dec-11 Rush University http://ClinicalTrials.gov/show/NCT00729690
Sen
Medical Center
PAIN
Drug: Control; Drug: Knee Osteoarthritis
Etoricoxib
Not yet 120
Rec
Adt
Sen
Jul-11 Nov-11 Singapore
General
Hospital; Merck
Drug: dabigatran
Venous
Thromboembolism;
Arthroplasty,
Replacement
Term
167
Adt Aug-10 Nov-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Drug:
Levobupivacaine;
Drug: Ropivacaine
Pain; Arthroplasty,
Replacement, Knee
Susp
48
Adt Jan-09 Oct-11 NHS Tayside
Sen
Drug: Ketorolac;
Drug: NaCL
Postoperative Pain
Comp
60
Adt May-09 Sep-11 University of
Sen
Aarhus
Drug: Memantine;
Drug: Placebo
Pain, Post-operative;
THR; TKR; lumbar
spinal fusion
Rec
120
Sen
Washington;
Forest
Laboratories
259
Fibrin Glue or Tranexamic Acid for
study
NCT01306370
Drug: Tranexamic
Arthropathy of Knee
Rec
172 Adt
Acid; Drug: Fibrin
Sen
glue; Biological:
Fibrin glue; Other:
Habitual
haemostasis
Local Infiltration Analgesia or
Drug: ropivacaine,
Osteoarthritis
Rec
50
Adt
Intrathecal Morphine in Total Knee ketorolac and
Sen
Arthroplasty
epinephrine; Drug:
RCT, efficacy study
morphine
NCT00992082
The Analgesic Efficacy of Local
Drug:
Total Knee
Rec
42
Adt
Anaesthetic Wound Infiltration
Levobupivacaine;
Replacement
Sen
Versus Intrathecal Morphine for
Drug: Intrathecal
morphine
NCT01312415
Dose-confirmatory Bridging Study Drug: Rivaroxaban Venous
Comp 302 Adt
in Total Knee Replacement
(BAY59-7939); Drug: Thromboembolism
Sen
Rivaroxaban
study
(BAY59-7939); Drug:
NCT01206972
Rivaroxaban
(BAY59-7939); Drug:
Enoxaparin
Optimizing Local Anesthetic
Drug: 0.1% and 0.4% Total Knee
Comp 48
Adt
Concentration for Continuous
perineural ropivicaine Arthroplasty; Knee
Sen
Femoral Nerve Blocks
Pain
NCT00923598
Dabigatran Etexilate vs
Drug: Dabigatran
Arthroplasty,
Comp 2615 Adt
Enoxaparin in Prevention of
Dose 1 - day 2 to
Replacement, Knee;
Sen
Venous Thromboembolism (VTE) completion; Drug:
Thromboembolism
Post Total Knee Replacement
Dabigatran Dose 1 Phase III: RCT, safety/efficacy
day 1; Drug:
study
Dabigatran Dose 2 NCT00152971
day 2 to completion;
Drug: Dabigatran
Dose 2 - day 1; Drug:
Enoxaparin
260
Jun-10 Sep-11 FundaciÃ³
Institut de
Recerca de
l'Hospital de la
Santa Creu i
Sant Pau
Aug-09 Aug-11 University
Hospital Orebro
Aug-10 Jun-11 Cork University http://ClinicalTrials.gov/show/NCT01312415
Hospital
Oct-10 Jun-11 Bayer
Jun-09 Apr-11 University of
California, San
Diego; The
Cleveland Clinic
Nov-04 Feb-11 Boehringer
Ingelheim
Pharmaceuticals
Morphine Consumption in Joint
Replacement Patients, With or
Without Gabapentin Treatment
RCT, efficacy study
NCT01307202
Steroids in Bilateral Total Knee
Replacement
study
NCT01399268
ED50 and ED95 of Intrathecal
Bupivacaine With or Without
Epinephrine for Total Knee
Replacement Arthroplasty
RCT, efficacy study
NCT01264575
Drug: Gabapentin;
Drug: Placebo
Post Operative Pain; Comp
Total Knee
Replacement
101
Drug:
Hydrocortisone;
Drug: Saline
Postoperative
Inflammatory
Response
Comp
34
Spinal Anesthesia;
Total Knee
Replacement
Arthroplasty
Comp
162
Total Knee
Arthroplasty
Term
90
Drug: intrathecal
bupivacaine 6mg +
100mcg OR 200mcg
epinephrine;
Intrathecal
bupivacaine 7mg +
100mcg OR 200mcg
epinephrine;
Intrathecal
bupivacaine 8mg +
100mcg epinephrine
OR 200mcg;
intrathecal
bupivacaine 9mg +
100mcg epinephrine
OR 200mcg;
intrathecal
bupivacaine 10mg +
100mcg OR 200mcg
epinephrine;
intrathecal
bupivacaine 11mg +
epinephrine 100mcg
OR 200mcg
The Effects of Dexamethasone on Drug: Ropivacaine;
the Duration of Sciatic Nerve
Drug:
Blocks
Dexamethasone;
Drug:
NCT00616603
Dexamethasone;
Drug: Normal Saline
261
Adt Oct-07 Feb-11 McMaster
Sen
University;
Hamilton Health
Sciences
Corporation
Adt Feb-09 Feb-11 Hospital for
Sen
Special Surgery,
New York; Dept.
Anesthesiology,
Hospital for
Special Surgery
Adt Dec-09 Jan-11 Seoul Medical
Sen
Center
Adt Aug-07 Jan-11 Loma Linda
Sen
University
A Study of BIBR 1048 in
Drug: Dabigatran
Arthroplasty,
etexilate; Drug:
Replacement, Knee;
Thromboembolism in Patients With Dabigatran etexilate; Venous Thrombosis
TKR Surgery.
Drug: Dabigatran
Etexilate; Drug:
NCT00246025
placebo
RE-MODEL Dabigatran Etexilate Drug: enoxaparin;
Arthroplasty,
150mg or 220mg Once Daily (o.d.) Drug: dabigatran
Replacement, Knee;
Versus (v.s.) Enoxaparin 40mg
etexilate; Drug:
Thromboembolism
o.d. for Prevention of Thrombosis dabigatran etexilate
After Knee Surgery
study
NCT00168805
Spinal Anaesthesia for Knee
Drug: Lidocaine
Spinal Anesthesia;
Arthroscopy: Does Lignocaine
added to bupivacaine Knee arthroplasty
Shorten the Effect of Bupivacaine for spinal
Phase IV: RCT, safety/efficacy anaesthesia
study
NCT01245868
Double Blind Efficacy and Safety Drug: Flexible dose Postoperative Pain
Study of Flexible-Dose vs LowQ8003 (morphine
Dose Q8003 After Undergoing
sulfate and
Primary Unilateral Total Knee
oxycodone
Arthroplasty
hydrochloride); Drug:
Low dose Q8003
study
(morphine sulfate
NCT01055015
and oxycodone
hydrochloride)
Perioperative Analgesia for Knee Femoral nerve block Elective primary
Arthroplasty (PAKA) - a pilot
(Levobupivicaine);
unilateral total knee
randomised trial
Peri-articular
replacement
RCT
infiltration
ISRCTN29107680
(Levobupivacaine,
Morphine +
Ketorolac)
Comp
512
Adt Oct-05 Jan-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Comp 2101 Adt Nov-04 Jan-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
Comp
60
Adt Nov-09 Dec-10 Hospital of
Frederikssund
Comp
141
Adt Feb-10 Dec-10 QRxPharma Inc. http://ClinicalTrials.gov/show/NCT01055015
Sen
Comp
46
N/K Jan-10 Dec-10 University of
Warwick (UK)
262
Effect of Body-mass Index (BMI) Drug: BPV6NO;
on Median Effective Dose of
Drug: BPV7NO;
Intrathecal Hyperbaric Bupivacaine Drug: BPV8NO;
RCT, efficacy study
Drug: BPV9NO;
NCT01291186
Drug: BPV10NO;
Drug: BPV11NO;
Drug: BPV6O; Drug:
BPV7O; Drug:
BPV8O; Drug:
BPV9O; Drug:
BPV10O; Drug:
BPV11O
Postoperative Patient Controlled Drug:
Epidural Analgesia After Total
Levobupivacaine
Knee Arthroplasty With 2ug/ml
Fentanyl Combine With 0.2%
Ropivacaine or 0.2%
Levobupivcaine
Phase IV: RCT, bio-equivalence
study
NCT01158586
Efficacy of Multimodal
Drug: Periarticular
Perioperative Analgesia With
Injection - Group A;
Periarticular Drug Injection in Total Drug: Periarticular
Knee Arthroplasty(TKA)
Injection - Group B;
RCT, efficacy study
Drug: Periarticular
NCT01042093
Injection - Group C;
Drug: Periarticular
Injection - Group D
Switching Drug Therapy for the
Drug: Rivaroxaban
Prevention of Blood Clot Formation
From Enoxaparin to Rivaroxaban
After Orthopedic Surgery for Either
Total Hip or Total Knee
Replacement
Phase III: RCT,
NCT01094886
Study of Transdermal Fentanyl
Drug: transdermal
Patch to Treat Postoperative Pain fentanyl patch; Drug:
in Total Knee Arthroplasty
placebo patch
study
NCT01348984
Arthroplasty, Knee
Arthroplasty,
Replacement, Knee;
Patient-controlled
Analgesia
Total Knee
Replacement
Comp
108
Adt Jan-10 Dec-10 Seoul Medical
Sen
Center
Rec
60
Adt Apr-10 Dec-10 United Christian http://ClinicalTrials.gov/show/NCT01158586
Sen
Hospital
Not yet 200
Rec
Adt Jan-10 Dec-10 Towson
Sen
Orthopaedic
Associates
Arthritis;
Comp
Thromboembolism
56
Adt Feb-10 Dec-10 Ortho-McNeil
Sen
Janssen
Scientific Affairs,
LLC
Postoperative Pain
40
Adt Apr-10 Dec-10 Khon Kaen
Sen
University
Comp
263
OXN PR Compared to OXY PR in
Subjects With Postoperative Pain
After Knee Arthroplasty
NCT01083485
Pregabalin, Celecoxib, Total Knee
Arthroplasty and Intrathecal
Morphine
NCT01344213
Drug:
Oxycodone/Naloxon
e PR 20/10mg or
10/5mg tablets;
Drug: Oxycodone
Drug: Pregabalin;
Drug: Celecoxib;
Drug: Pregabalin
with celecoxib; Drug:
Placebo
Post Operative Pain
Comp
137
Adt Mar-10 Nov-10 Mundipharma
Sen
Oy
Postoperative Pain
Management; Total
Knee Arthroplasty
Comp
100
Adt
Sen
Local Infiltration With Bupivacaine
to Increase Quality of Postoperative Pain Control in Total
Knee Replacement
NCT01364194
A randomised controlled trial to
determine if local wound infiltration
reduces chronic pain after lower
limb arthroplasty
RCT
ISRCTN96095682
Drug: 0.25%
Bupivacaine; Drug:
0.9% normal saline
Arthropathy of Knee
Joint
Comp
60
Comp
600
Adt Nov-09 Sep-10 Southmead
Sen
Hospital (UK)
Rec
168
Adt May-09 Sep-10 University Health http://ClinicalTrials.gov/show/NCT00803348
Sen
Network,
Toronto
Continuous Femoral Nerve
Blockade and Readiness to
Discharge Following Total Knee
Arthroplasty
RCT, efficacy study
NCT00803348
Injection of local
Hip replacement;
anaesthethic into
Knee replacement
joint during joint
replacement +
standard
anaesthetic;
standard anaesthetic
alone
Drug: Bolus of 0.2% Knee Arthroplasty
ropivicaine 20 mls
followed by 0.2%
ropivicaine at an
infusion rate of
5mls/hr until 0600 on
postoperative day 2;
Drug: Bolus of 0.2%
ropivicaine 20 mls
followed by 0.1%
ropivicaine at an
infusion rate of
10mls/hr until 0600
on post-operative
day 2; Drug: Saline
control
264
Jul-08 Oct-10 Chulalongkorn http://ClinicalTrials.gov/show/NCT01344213
University;
Bhumibol
Adulyadej
Hospital; King
Chulalongkorn
Memorial
Hospital
Adt Mar-10 Sep-10 Mahidol
Sen
University; Siriraj
Hospital
Antibiotic Prophylaxis in Total
Knee Prosthesis
NCT00497341
The Use of FLOSEAL to Reduce
Bleeding in Total Knee
Replacement Surgery
NCT00990288
Drug: cefuroxime;
Drug: placebo
Infection
Drug: Hemostatic
Matrix
Hemorrhage
Hemorrhage Risk Prescribed
Arixtra
NCT01064362
Drug: Fondaparinux
sodium; Drug: Low
molecular weight
heparin (LMWH)
Prospective, Randomized
Controlled Trial on Perioperative
Pregabalin to Reduce Late-onset
CRPS After TKA
NCT00558753
Clinical Trial for Fibrin Sealant in
Knee Surgery
RCT, efficacy study
NCT00440921
Additional Anti-emetic Effect of
Ramosetron Prophylaxis After
NCT01102491
Single Intravenous Administration
of TB-402 for the Prophylaxis of
Venous Thromboembolic Events
(VTE) After Total Knee
Replacement Surgery
study
NCT00793234
Drug: pregabalin;
Drug: Placebo
Knee Replacement
Surgery;
Haemorrhage;
Thrombosis,
Venous; Hip
Replacement
Surgery; Hip
Fracture Surgery
Complex Regional
Pain Syndromes
Drug: Single donor
Allogenous Fibrin
Sealant
Drug: Ramosetron
Rec
1332 Adt Jan-08 Aug-10 Hospital Clinic of http://ClinicalTrials.gov/show/NCT00497341
Sen
Barcelona
196 Child Oct-07 Aug-10 Hospital for
Adt
Special Surgery,
Sen
New York;
Baxter
Healthcare
Corporation
Comp 1344 Adt Jan-10 Jun-10 GlaxoSmithKline http://ClinicalTrials.gov/show/NCT01064362
2
Sen
Comp
240
Adt Apr-06 Jun-10 Rush University http://ClinicalTrials.gov/show/NCT00558753
Sen
Medical Center;
Pfizer
Total Kneereplacement; Total
Hip-replacement
Wdrwn 578
Comp
153
Adt Dec-08 Jun-10 Sanquin
Sen
Research &
Blood Bank
Divisions; MDM
Adt Sep-09 Mar-10 Seoul National http://ClinicalTrials.gov/show/NCT01102491
Sen
University
Hospital
Comp
316
Drug: TB-402; Drug: Total Knee
Enoxaparin
Replacement
Surgery
Comp
265
Adt Dec-08 Mar-10 ThromboGenics; http://ClinicalTrials.gov/show/NCT00793234
Sen
BioInvent
International AB;
Covance
A Phase 3 Study of DU-176b,
study
NCT01181102
Safety and Efficacy Study of KAI1678 to Treat Subjects With
Postoperative Pain
study
NCT01015235
Procedure
Long-Term Multicenter Evaluation
of the E1® Tibial Bearing
NCT01374230
Computer Navigation vs
Conventional Technique in Knee
Arthroplasty
RCT, efficacy study
NCT00782444
Posterior cruciate ligament and
total knee arthroplasty: retain,
sacrifice or substitute? A
prospective, randomised clinical
trial
RCT, efficacy study
ISRCTN82612978
Hospital for Special Surgery Knee
Arthroplasty Cohort
NCT00454467
Drug: edoxaban;
Drug: enoxaparin
sodium
Prevention; Venous
Thromboembolism
Comp
716
Adt Mar-09 Feb-10 Daiichi Sankyo http://ClinicalTrials.gov/show/NCT01181102
Sen
Inc.; Daiichi
Sankyo, Tokyo,
LTD.
Drug: Placebo; Drug: Pain, Postoperative;
THR; TKR
KAI-1678; Drug:
Ketorolac
Tromethamine
Comp
90
Adt Dec-08 Feb-10 KAI
Sen
Pharmaceuticals
; Trident Clinical
Research Pty
Ltd
Procedure: Total
knee arthroplasty
Not yet
Rec
50
Adt Sep-11 Sep-21 Massachusetts http://ClinicalTrials.gov/show/NCT01374230
Sen
General Hospital
Procedure: computer Knee Osteoarthritis; Active,
navigation
NR
200
Total Knee
Arthroplasty (TKA)
with Posterior
Cruciate Ligament
(PCL) retained;
TKA with PCL
excised, but not
replaced; TKA with
PCL excised and
replaced with
posterior stabilised
implant
285
Adt Jan-09 Dec-18 Haukeland
Sen
University
Hospital; The
Research
Council of
Norway
Adt Apr-06 Dec-18 Helsinki
University
Central Hospital
(Finland)
Knee; Traumatic
Arthritis of the Knee
Severe Knee
Osteoarthritis
Knee Arthroplasty
Active
Rec
3000 Adt Apr-07 Apr-17 Hospital for
Sen
Special Surgery,
New York;
Agency for
Healthcare
Research and
Quality (AHRQ)
266
Total or Partial Knee Arthroplasty
Trial
RCT, efficacy study
NCT01352247
Procedure:
Unicompartmental
Knee Replacement;
Procedure: Total
Knee Replacement
Articulating Versus Static Antibiotic Procedure: Static
Loaded Spacers for the Treatment Spacer; Procedure:
of Prosthetic Knee Infection
Articulating Spacer
RCT, efficacy study
NCT01373112
Outcomes After Total Knee Joint
Arthroplasty : A Comparative
Study Using 3 Different Analgesic
Techniques
study
NCT01503528
Motion Analysis of EMP Knee
Versus Posterior Stabilized Knee
Arthroplasty for Osteoarthritis
RCT
NCT00967161
Clinical and Stereoradiological
Comparison of the Results After
Primary Cemented Total Knee
Arthroplasty Inserted With or
Without the Use of a Tourniquet
NCT01488175
Cemented Versus Cementless
Tibial Prosthesis Study
NCT01041937
Knee Osteoarthritis
Rec
500
Adt Jan-10 Dec-16 University of
Sen
Oxford;
University of
Aberdeen
Rec
140
Infection; Prosthetic
Joint Infection;
Complications;
Arthroplasty,
Infection or
Inflammation;
Complications;
Arthroplasty
Knee Joint Arthritis; Not yet 750
Knee Joint
Rec
Arthroplasty
Adt Dec-11 Aug-16 Rush University http://ClinicalTrials.gov/show/NCT01373112
Sen
Medical Center;
Central DuPage
Hospital
50
Adt Jan-12 Jun-15 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00967161
Sen
Research
Institute; Wright
Medical
Technology
Sen
University
Hospital
Procedure: Spinal
anesthesia with
periarticular
infiltration;
Procedure: Femoral
and sciatic nerve
blocks; Procedure:
Periarticular
infusions
Procedure: Total
Arthropathy of Knee Not yet
Knee Arthroplasty; Joint
Rec
Procedure: Motion
analysis
Procedure:
tourniquet;
Procedure: no
tourniquet
Knee
Not yet
Rec
60
Procedure:
Cemented Tibia;
Procedure:
Cementless Tibia
Osteoarthritis; Post- Active,
traumatic
NR
Osteoarthritis;
250
267
Adt Jun-12 Aug-15 Lawson Health
Sen
Research
Institute
Adt Dec-09 Dec-14 Washington
Sen
University
School of
Medicine; Wright
Medical
Technology
Comparison of Three Tourniquet
Application Methods in Primary
Total Knee Arthroplasty Surgery
RCT
NCT01355900
Application of Radiostereometric
Analysis (RSA) to Triathlon Knee
Components Inserted Using the
OtisMed Custom-fit Total Knee
Replacement System
RCT, efficacy study
NCT01262430
Effect of Preop Nutritional Status
on Outcomes of Staged Bilateral
NCT01545362
Patellar Resurfacing in Total Knee
Arthroplasty
RCT, efficacy study
NCT00553982
Adductor-Canal-Blockade Versus
the Femoral Nerve Block Effect on
Muscle Strength, Pain and
Mobilization After Total Knee
Replacement
RCT, efficacy study
NCT01470391
Total Knee Arthroplasty Accelerated Recovery Without
Tourniquet
RCT
NCT01309035
Dilute Betadine Lavage in the
Prevention of Postoperative
Infection
NCT01175044
Procedure: Total
knee arthroplasty
performed under
tourniquet
Knee Osteoarthritis
Procedure: OtisMed; Osteoarthritis
Procedure:
Computer Assisted
Surgery (CAS)
Procedure: Total
knee arthroplasty
Arthritis
Procedure: Patellar Osteoarthritis; Pain
component;
Procedure: No
patellar component
Procedure: Adductor- Total Knee
Canal-Blockade;
Arthroplasty
Procedure: Femoral
Nerve Block
Procedure: Total
Knee Arthroplasty
Osteoarthrosis in
Knee-joint
Procedure: Betadine Prosthesis-Related
Lavage; Procedure: Infections;
Arthroplasty; TKA
Saline Lavage
Rec
120
Adt Jan-10 Dec-14 Vilnius
Sen
University;
Karolinska
Institutet
Rec
50
Adt Apr-11 Apr-14 Dalhousie
Sen
University
Invite
100
Adt Nov-11 Mar-14 Heekin
Sen
Orthopedic
Research
Institute
Active,
NR
110 Child Oct-07 Dec-13 Sykehuset
Adt
Innlandet HF
Sen
Rec
55
Adt Nov-11 Sep-13 Rigshospitalet,
Sen
Denmark
Rec
60
Adt Mar-11 Sep-13 Northern
Sen
Orthopaedic
Division,
Denmark
Rec
600
Adt Aug-10 Aug-13 Rush University http://ClinicalTrials.gov/show/NCT01175044
Sen
Medical Center;
Central DuPage
Hospital
268
Efficacy and Patient Satisfaction
With AQUACEL® Ag Surgical
Dressing Compared to Standard
Surgical Dressing
NCT01258270
Total knee arthroplasty versus
patellofemoral arthroplasty in
patients with severe arthritis of the
patellofemoral joint
RCT
ISRCTN34863373
Minimally Invasive Knee
Replacement Outcomes (MIKRO)
Study
RCT, efficacy study
NCT00633113
Anatomic Reconstruction of the
Patellofemoral Joint
NCT01375231
Procedure: Postop Wound Healing;
Dressing; Procedure: TKA; THA
Postop Dressing
Rec
300
Adt Dec-10 Aug-13 OrthoCarolina
Sen
Research
Institute, Inc.;
ConvaTec Inc.
Total knee
arthroplasty;
Patellofemoral
arthroplasty
Patellofemoral
osteoarthritis
Active
64
Adt Mar-09 Apr-13 University of
Sen
Warwick (UK)
Procedure: MPPA;
Procedure: SV
Knee Osteoarthritis
Active,
NR
128
Adt Nov-07 Mar-13 Dartmouthhttp://ClinicalTrials.gov/show/NCT00633113
Sen
Hitchcock
Medical Center;
Zimmer, Inc.
Procedure:
Knee Replacement Active, 52 Child Jun-11 Jan-13 OrthoCarolina
Measured Resection Surgery
NR
Adt
Research
of patellofemoral
Sen
Institute, Inc.
joint; Procedure:
Measured resection
of patella
Minimally Invasive Versus
Procedure:
Osteoarthritis;
Rec
50 Child Nov-07 Jan-13 Aesculap AG
Conventional Approaches in
Navigated TKA with Rheumatoid Arthritis;
Adt
Navigated Total Knee Arthroplasty a minimally invasive Post-traumatic
Sen
(TKA)
approach;
Arthritis
Procedure:
NCT00839020
Navigated TKA with
a conventional
approach
MR Imaging of Knee Osteoarthritis Procedure: ACL
Osteoarthritis, Knee Active, 145 Adt Aug-06 Dec-12 University of
and Acute Knee Injuries
Reconstruction
NR
Sen
California, San
Prospective, case control study Surgery; Procedure:
Francisco;
NCT00504114
Cartilage
National
Resurfacing Surgery;
Institutes of
Procedure: Total
Health
Knee Replacement
Saphenous Nerve Block vs.
Procedure: Study
Difference Between Not yet 60
Adt Feb-12 Nov-12 Hospital for
Femoral Nerve Block for Total
Technique;
Femoral Nerve Block Rec
Sen
Special Surgery,
Knee Arthroplasty
Procedure: Control and Saphenous
New York
Technique
Block
NCT01505374
269
Perioperative Analgesia After Knee Procedure:
Knee Arthroplasty
Arthroplasty
Continuous femoral
nerve block +
NCT01225484
periarticular
infiltration;
Procedure:
Intraarticular and
periarticular
ropivacaine
A Randomized Controlled Trial of Procedure: Waiting Osteoarthritis
Long Versus Short Wait For
time (access time to
Total joint
Arthroplasty
replacement)
NCT00138892
Early Ambulation After Adductor Procedure: Canal
Pain; Osteoarthritis
Canal Block for Total Knee
Block and Capsular
Arthroplasty
RCT, efficacy study
Femoral Nerve Block
NCT01459861
with Tibial Nerve
Block
Osteoarthritis; TKA;
Study Comparing Peri-articular
Procedure: PeriInjection of Bupivacaine With and articular injection of THA
Without Epinephrine
marcaine/epinephrin
RCT, efficacy study
e; Procedure: PeriNCT00737139
articular injection of
marcaine alone
Effect of Prophylactic Antibiotics Procedure:
Infection;
Arthroplasty; Hip;
on Intra-Operative Culture Results Prophylactic
Knee
Antibiotics;
NCT01174212
Procedure: Control
Antibiotics
Effect of a Sciatic Nerve Block
Procedure:
Postoperative Pain
Combined With a Continuous
Analgesia for knee
Femoral Block on Pain Scores
arthroplasty
After Knee Arthroplasty
RCT, efficacy study
NCT01337115
Preoperative Alignment of Total
Procedure:
Knee Arthritis
Knee Replacement
customized knee
RCT, efficacy study
instruments;
NCT01242085
Procedure: total knee
replacement
Rec
123
Adt Oct-10 Oct-12 Landeskrankenh http://ClinicalTrials.gov/show/NCT01225484
Sen
aus Feldbach;
Medical
University of
Graz
Active,
NR
236
Adt Aug-02 Oct-12 University of
Sen
British Columbia
Rec
56
Adt Oct-11 Sep-12 Saint Francis
Sen
Care
Rec
240
Adt Sep-08 Sep-12 Rush University http://ClinicalTrials.gov/show/NCT00737139
Sen
Medical Center
Rec
200
Adt
Sen
Active,
NR
50
Rec
60
270
Jul-10
Jul-12 Rush University http://ClinicalTrials.gov/show/NCT01174212
Medical Center;
Rothman
Institute
Orthopaedics
Child Apr-11 Jun-12 Centro
Adt
Hospitalar do
Sen
Porto;
Universidade do
Porto
Adt Nov-10 Jun-12 VA Palo Alto
Sen
Health Care
System; DePuy
Orthopaedics
Effectiveness of Minimally Invasive Procedure: Minimally Osteoarthritis
Total Knee Replacement in
Invasive Total Knee
Improving Rehabilitation and
Arthroplasty
Function
[TKA(min)];
Procedure: Total
NCT00710840
Knee Arthroplasty
(TKA)
Standard Total Knee Arthroplasty Procedure: Total
Osteoarthritis
Using Platelet Rich Plasma (PRP) knee arthroplasty
RCT, efficacy study
NCT01075230
Intraoperative Posterior Cruciate Procedure:
Arthroplasty,
Ligament (Transcruciate) Injection transcruciate
Replacement, Knee
injection of 20cc of
(TKA)
normal saline;
Procedure:
NCT01345604
transcruciate
injection of 20 cc of
0.5% Ropivacaine
New Tool of Subjective and
Procedure:
Hip Arthritis; Knee
Objective Functional Evaluation
Arthroplasty
Arthritis
and the Quality of Life After
Arthroplastic Surgery of the Hip
and the Knee Assisted or Not by
Computer and Mini-invasive
Arthroplasty
RCT
NCT00894218
Effectiveness of Acupuncture as Procedure:
Total Knee
an Adjunct to Rehabilitation After Acupuncture;
Replacement
Knee Arthroplasty
Procedure: exercises
NCT00935155
Review on Minimally Invasive Skin Procedure: Incision Gonarthrosis
Incision in Vanguard PS Artificial technique;
Patients Who Need
Knee Joint System
Procedure: Incision Artificial Knee Joint
technique
Total Replacement
NCT01010828
Active,
NR
75
Adt Jun-08 Jun-12 Greg Olender; http://ClinicalTrials.gov/show/NCT00710840
Sen
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Active,
NR
100 Child Feb-10 Jun-12 Exactech
Adt
Sen
Invite
40
Child May-11 May-12 University of
Adt
Saskatchewan;
Sen
Saskatoon
Health Region
Rec
80
Adt Apr-09 Apr-12 Assistance
Sen
Publique
Hopitaux De
Marseille
Rec
170
Adt Jan-09 Mar-12 Back and
Sen
Rehabilitation
Center,
Copenhagen
Rec
72
Child Nov-09 Mar-12 Biomet, Inc.;
Adt
Biomet Japan,
Sen
Inc.
271
The Efficacy of Adductor-CanalBlockade on Pain and Morphine
Consumption After Revision Knee
Arthroplasty
Phase IV: RCT
NCT01191593
The Effect of Ischemic
Preconditioning on Postoperative
Pain After Total Knee Arthroplasty,
a Randomized, Controlled Trial
NCT01333969
Continuous Saphenous Nerve
Block for Total Knee Arthroplasty
RCT, efficacy study
NCT01332045
Procedure: Adductor- Postoperative Pain;
Canal-Blockade with Knee Arthroplasty
Ropivacaine;
Procedure: AdductorCanal-blockade with
saline
Procedure: Ischemic Total Knee
Preconditioning
Arthroplasty;
Ischemic
Preconditioning;
Postoperative Pain
Procedure:
Pain, Postoperative
continuous
saphenous nerve
block; Procedure:
Saline boluses in
nerve catheter
General vs. Intrathecal Anesthesia Procedure: General Arthritis
for Total Knee Arthroplasty
anesthesia;
RCT
Procedure: Regional
NCT01312298
anesthesia
Anterior Referencing Versus
Procedure: Total
Osteoarthritis
Posterior Referencing in Minimally knee
Invasive Total Knee Arthroplasty
RCT, efficacy study
NCT01135030
Continuous Saphenous Block
Procedure:
Total Knee
Versus Continuous Femoral Block continuous femoral Arthroplasty
for Total Knee Arthroplasty
nerve block;
Secondary to
RCT
Procedure:
Osteoarthritis
NCT01250041
continuous
saphenous nerve
block
Do We Need Computer Assistance Procedure: NonOsteoarthritis
To Improve the Survival of Primary Computer Assistance
Total Knee Arthroplasty. A
TKA; Procedure:
Minimum Ten Years Follow-up
Computer Assistance
Phase IV: RCT
TKA
NCT01520571
Rec
36
Adt Sep-10 Feb-12 Rigshospitalet,
Sen
Denmark
Rec
60
Comp
40
Adt Apr-11 Feb-12 Hospital for
Sen
Special Surgery,
New York;
University of
Massachusetts,
Worcester
Adt Apr-11 Jan-12 Henning Lykke http://ClinicalTrials.gov/show/NCT01332045
Sen
Andersen
Not yet 120
Rec
Adt Aug-11 Jan-12 Region Skane
Sen
Comp
100
Not yet
Rec
40
Adt Oct-06 Jan-12 Heekin
Sen
Orthopedic
Research
Institute; Stryker
Orthopaedics
Adt Jan-11 Dec-11 McGill University http://ClinicalTrials.gov/show/NCT01250041
Sen
Health Center
Comp
520
272
Adt Jan-00 Dec-11 Ewha Womans
Sen
University
Early Neuromuscular Electrical
Procedure:
Osteoarthritis
Stimulation For Quadriceps Muscle Neuromuscular
Activation Deficits Following Total Electrical Stimulation
Knee Replacement
(NMES); Behavioral:
Standard
NCT00800254
Rehabilitation
Protocol
Comp
66
Comparing Postoperative
Procedure: Sciatic
Total Knee
Rec
96
Functional Recovery and
Nerve Block;
Arthroplasty; Post
Analgesic Efficacy of a Single Shot Procedure: Posterior Operative Analgesia
Sciatic Nerve Block Versus
capsule infiltration
Posterior Capsule/Fat Pad
with local anesthetic;
Infiltration of Local Anesthetic for Procedure: Sham
sciatic block and
RCT, efficacy study
sham posterior
NCT00677261
infiltration
Saphenous Nerve Block Versus
Procedure: Study
Total Knee
Comp 73
Femoral Nerve Block for Total
Group: Experimental; Arthroplasty
Knee Arthroplasty
Procedure: Control
Phase IV: RCT, safety/efficacy Group
study
NCT01333943
An Efficacy and Safety Study of
Procedure: parecoxib Unilateral Primary
Not yet 125
Periarticular Parecoxib Sodium for sodium; Procedure: Osteoarthritis of
Rec
Pain Management in Total Knee parecoxib sodium
Knee
Arthroplasty
study
NCT01311804
Accuracy of MRI-based Patients Procedure: Patient Osteoarthritis of
Comp 80
Matched Instruments vs Jig-based matched
Knee
Instruments in Total Knee
instruments;
Arthroplasty (TKA)
Procedure: Jig based
RCT, efficacy study
instruments
NCT01449474
273
Adt Oct-08 Nov-11 Greg Olender; http://ClinicalTrials.gov/show/NCT00800254
Sen
National Institute
on Aging (NIA);
University of
Colorado,
Denver;
American
College of
Rheumatology
Research and
Education
Foundation
Adt Jun-08 Nov-11 Sunnybrook
Sen
Health Sciences
Centre
Adt Mar-11 Nov-11 Hospital for
Sen
Special Surgery,
New York
Adt Apr-11 Oct-11 Ministry of
Sen
Health, Malaysia
Adt Apr-11 Oct-11 Mahidol
Sen
University
Prediction of Pain in Total Knee
Arthroplasty
NCT01179204
The Recovery Time of Quadriceps
Strength After Total Knee
Arthroplasty (TKA): The Effect of
Quadriceps Incision Length
RCT, efficacy study
NCT01450904
The Efficacy of Adductor-CanalBlockade on Pain and Morphine
Consumption After Total Knee
Arthroplasty
NCT01261897
Minimal Versus Conventional
Exposure in Unicompartmental
Knee Arthroplasty
RCT, efficacy study
NCT00991445
Minimally Invasive Surgical
Approaches In Total Knee
Arthroplasty
RCT, efficacy study
NCT01461356
Navigated EM Total Knee
Replacement: Accuracy Study
NCT00512421
Arthroplasty: Peri-Articular
Injection Versus Epidural +
Femoral Nerve Blockade
NCT01335542
Patellofemoral Pain After
Unicondylar Knee Arthroplasty
NCT01407042
Procedure:
Preoperative heat
stimulation
Pain, Postoperative
Comp
100
Adt Aug-10 Oct-11 Hvidovre
Sen
University
Hospital
Procedure:
Osteoarthritis of
Quadriceps incision Knee
< 2 cm; Procedure:
Quadriceps incision
2-4 cm; Procedure:
Quadriceps incision
> 4 cm
Procedure: Adductor- Postoperative Pain;
Canal-Blockade with Knee Arthroplasty
Ropivacaine;
saline
Procedure: Minimal Knee Osteoarthritis
Invasive Surgery;
Procedure:
Conventional
exposure
Procedure: Minimally Knee Osteoarthritis
invasive total knee
replacement;
Procedure: Standard
approach total knee
replacement
Procedure:
Total Knee
computer-assisted Replacement
surgery
Comp
60
Adt Apr-11 Oct-11 Mahidol
Sen
University
Comp
40
Adt Jan-11 Sep-11 Rigshospitalet,
Sen
Denmark
Rec
40
Adt May-09 Sep-11 University
Sen
Hospital Orebro
Comp
40
Adt Mar-07 Sep-11 Mayo Clinic
Sen
Term
200
Adt
Sen
Rec
90
Adt Mar-10 Aug-11 Hospital for
Sen
Special Surgery,
New York
Not yet
Rec
20
Adt Sep-11 Jul-11 Medical
Sen
University
Innsbruck
Procedure: PeriReadiness to
Articular Injection;
Discharge
Procedure: Epidural
Pathway
(PCEA+FNB)
Procedure: mobile- Mobile-bearing
bearing unicondylar Unicondylar Knee
knee arthroplasty
Arthroplasty
274
Aug-11 Hadassah
Medical
Organization
Rec
400
Adt Nov-07 Jul-11 Minneapolis
Sen
Veterans Affairs
Medical Center
(VAMC); Depuy,
Inc.
Wdrwn
90
Procedure: Adductor- Total Knee
Canal-Blockade;
Arthroplasty
saline
Comp
70
Adt Mar-07 Jun-11 HealthEast Care http://ClinicalTrials.gov/show/NCT00455182
Sen
System;
University of
Minnesota Clinical and
Translational
Science
Institute;
Northwestern
Health Sciences
University
Adt Aug-10 Mar-11 Rigshospitalet, http://ClinicalTrials.gov/show/NCT01104883
Sen
Denmark
Procedure: Surgical Osteoarthritis
approach for total
knee arthroplasty
Comp
126 Child Jan-05 Mar-11 Capital District http://ClinicalTrials.gov/show/NCT00346788
Adt
Health Authority,
Sen
Canada
Procedure: Total
Knee Arthroplasty
Knee
with Custom Cutting
Blocks; Procedure:
Total Knee
Arthroplasty via
Computer Assisted
Surgery
Comp
60
Comparison of a Metal Backed
Procedure: TKA
Fixed-Bearing Tibial Baseplate and surgery with modular
an All-Polyethylene Tibia in Total polished tibial
Knee Arthroplasty
baseplate/XLK
Phase IV: RCT, safety/efficacy design; Procedure:
study
TKA surgery with the
NCT00979147
nonmodular
APT/GVF design;
Device: P.F.C.®
Sigma Knee System;
Device: P.F.C.®
Sigma Knee System
Acupuncture for Pain Management Procedure:
Pain; Postoperative
After Hip or Knee Arthroplasty
Acupuncture;
Complications
RCT, efficacy study
Procedure: Sham
NCT00455182
Acupuncture;
Procedure: Standard
medical care
The Efficacy of Adductor-CanalBlockade on Morphine
Consumption, Pain and
Mobilisation After Total Knee
Arthroplasty
study
NCT01104883
The Subvastus Approach in Total
Knee Arthroplasty
Phase IV: RCT
NCT00346788
A Comparative Study of Knee
Systems
Phase IV: RCT
NCT01331278
275
Adt Sep-09 Mar-11 Foundation for
Sen
Southwest
Orthopedic
Research
Does intramedullary plugging
Intramedullary
reduce blood transfusion
plugging with
requirements in total knee
retransfusion drains;
replacement?
Retransfusion drains
RCT
only
ISRCTN94713892
Management of Postoperative
Procedure:
Pain Following Total Knee
acupunctureArthroplasty by Using
moxibustion therapy;
Acupuncture-moxibustion Therapy Procedure: Regular
Phase II/III: RCT
therapy
NCT01047384
Short- Versus Long-duration
Procedure: Long
Tourniquet Use During Total Knee duration tourniquet;
Replacement (TKR)
Procedure: Short
duration tourniquet
NCT01162720
Tibial Nerve Versus Sciatic Nerve Procedure: Selective
Block
Tibial Nerve block;
RCT
Procedure: Sciatic
NCT01415193
Nerve Block
A Comparison Between an
Procedure: Limb
Individual Low Tourniquet
occlusion pressure
Pressure Versus a Standard
(LOP); Procedure:
Pressure During Total Knee
conventional
Arthroplasty
measurement
RCT, efficacy study
method
NCT01442298
Effect of Ambulatory Continuous Procedure:
Femoral Nerve Blocks on
Ambulatory
Readiness-for-Discharge Following continuous femoral
nerve block for 100
RCT, efficacy study
hours
NCT00419276
Primary total knee
Comp
replacement surgery
100
Adt Dec-09 Jan-11 Royal Berkshire http://www.controlledSen
NHS Foundation trials.com/ISRCTN9471389
Trust (UK)
Osteoarthritis, Knee Not yet 100
Rec
Adt Jan-10 Jan-11 Chang Gung
Sen
Memorial
Hospital
Arthroplasty,
Replacement, Knee
Term
65
Adt Nov-08 Dec-10 Fairfield
Sen
Hospital,
Australia
Post Operative
Analgesia; TKA
Comp
80
Adt Mar-09 Dec-10 Saint Francis
Sen
Care
Complications;
Arthroplasty
Comp
164 Child Oct-08 Oct-10 Charlotta
Adt
Olivecrona
Sen
Total Knee
Arthroplasty
Comp
81
276
Adt Apr-07 Aug-10 National Institute http://ClinicalTrials.gov/show/NCT00419276
Sen
of General
Medical
Sciences
(NIGMS);
University of
Florida;
University of
California, San
Diego; Stryker
Instruments
Sub-Vastus Versus Mid-Vastus
Arthrotomy for Total Knee
Arthroplasty: a Randomized
Clinical Trial
RCT, efficacy study
NCT00925626
Does Tourniquet Use in Total
Knee Replacement Improve
Fixation
Phase III: RCT
NCT01470482
Procedure: SubVastus arthrotomy;
Procedure: Mid Vastus arthrotomy
Susp
100
Adt Jun-09 Aug-10 University
Sen
Hospital, Ghent
Comp
50
Adt Aug-06 May-10 Per Aspenberg
Sen
Osteoarthritis
Rec
162
Adt
Sen
Thromboembolism;
Arthroplasty, Knee;
Arthroplasty, Hip
Rec
Procedure: No use of Osteoarthritis, Knee
tourniquet;
Procedure:
Tourniquet
Other
Progressive Rehabilitation
Other: Total knee
Following Total Knee Arthroplasty replacement
rehabilitation
study
NCT01537328
Genetics Informatics Trial (GIFT)
of Warfarin to Prevent DVT
study
NCT01006733
Tricompartmental
Gonarthrosis
Other:
Pharmacogenetic
Other: Clinical
Warfarin Initiation
(nonpharmacogenetic);
Other:
Pharmacogenetic
Other: Clinical
Warfarin Initiation
(nonpharmacogenetic)
Jul-11 May-17 University of
Colorado,
Denver; National
Institutes of
Health; Eunice
Kennedy Shriver
National Institute
of Child Health
and Human
Development
1600 Adt Mar-11 Aug-15 Washington
Sen
University
School of
Medicine;
Intermountain
Health Care,
Inc.; University
of Utah; Hospital
for Special
Surgery, New
York; National
Heart, Lung, and
Blood Institute
(NHLBI)
277
Structured Treatment of
Osteoarthritis of the Knee With or
Without Total Knee Replacement
RCT, efficacy study
NCT01410409
Other:
Neuromuscular
Knee
training (NEMEXTJR); Drug:
Paracetamol; Drug:
Burana; Drug:
Pantoprazol;
Behavioral: Dietary
counseling;
Behavioral: Patient
education;
Procedure: TKR;
Other: Insoles
The Difference Between
Other: Rehabilitation Osteoarthritis, Knee
Rehabilitation With or Without
with strength training;
Strength Training After Total Knee Other: Rehabilitation
Replacement
without strength
Phase II/III: RCT, safety/efficacy training
study
NCT01351831
Visionaire™ Versus Standard
Other: Total Knee
Degenerative
Instrumentation Safety and
Arthroplasty; Other: Arthritis of Knee
Efficacy in Total Knee Arthroplasty Total Knee
(TKA)
Arthroplasty
NCT01084772
A Randomized Prospective Trial of Other: Instrument
Total Knee Arthroplasty Options
Comparing Standard Knee Cutting
Guides and MRI Generated
Patient Specific Custom Cutting
Guides
RCT
NCT01072019
Efficacy and Safety of FLOSEAL Other: Standard of Knee Replacement
for Hemostasis in Total Knee
Care; Drug:
Surgery;
Arthroplasty
FLOSEAL
Osteoarthritis
Phase IV: RCT, safety/efficacy Hemostatic Matrix
study
NCT01410240
Rec
100 Child Sep-11 Apr-14 Northern
Adt
Orthopaedic
Sen
Division,
Denmark
Rec
70
Adt Jan-11 Aug-13 Copenhagen
Sen
University
Hospital,
Hvidovre
Rec
196 Child Apr-10 Jun-13 Smith &
Adt
Nephew, Inc.
Sen
Invite
165
Adt Mar-10 Mar-13 Washington
Sen
University
School of
Medicine;
Biomet, Inc.
Rec
138
Adt Sep-11 Jan-13 Baxter
Sen
Healthcare
Corporation
278
Improving Function After Knee
Arthroplasty With Weight-Bearing
Biofeedback
Phase I: RCT
NCT01333189
POMX (Post Operative Morbidity):
Randomized controlled trial of
chewing gum to reduce
postoperative morbidity in elective
orthopaedic surgery
RCT, efficacy study
ISRCTN20301599
A Comparison of Sartorius Vs.
Quadriceps Evoked Motor
Response for Femoral Nerve to
Prevent Secondary Catheter
Failure
NCT01313546
Rehabilitation After Fast-track
RCT
NCT01329081
The Effectiveness of 8-weeks
Progressive Strength Training to
Patients With Unicompartmental
Knee Replacement, Initiated
Within the First Postoperative
Week
Phase III: RCT
NCT01345825
Gamma Vacuum Foil (GVF)
Versus Cross-linked Polyethylene
in Total Knee Arthroplasty Study
study
NCT00289133
Progressive Exercise After Total
Knee Arthroplasty (TKA)
RCT, efficacy study
NCT00605124
Other: WeightArthropathy of Knee
bearing biofeedback Joint
exercise; Other:
Standard of care
exercise
Chewing gum
hip and knee
arthroplasty
procedures
Rec
20
Sen
Colorado,
Denver
Active
106
(UK)
Other: Stimulation of Arthroplasty,
quariceps muscle
Replacement, Knee
Not yet
Rec
40
Adt May-11 Sep-12 Sunnybrook
Sen
Health Sciences
Centre
Other: Postoperative Knee Arthroplasty
rehabilitation after
fast-track TKA;
Other: Postoperative
rehabilitation after
fast-track TKA
Other: Resistance
Knee Osteoarthritis
training
Rec
140
Adt Apr-10 Jul-12 University of
Sen
Aarhus
Rec
60
Adt Mar-11 Jul-12 University of
Sen
Aarhus
Other: total knee
Osteoarthritis, Knee; Active,
arthroplasty; Device: Arthritis, Rheumatoid NR
total knee
arthroplasty
937
Adt Feb-05 Jun-12 DePuy
Sen
Orthopaedics
Other: Knee muscle Osteoarthritis
exercises
120
Adt Jan-08 Apr-12 Jyväskylä
Sen
Central Hospital
Rec
279
Comparison of Surgical Time and
Efficiency of Total Knee
Arthroplasty
NCT01301950
Long Term Follow-up of the
“Stryker Dacron and Trevira
Ligament” for Anterior Cruciate
Ligament (ACL) Repair"
NCT01138696
Effect of Physiotherapy After Total
Knee Replacement
RCT, efficacy study
NCT00807716
Role of Bone in Knee
Osteoarthritis (OA)
NCT00850538
Preoperative Exercise in Patients
Undergoing Total Hip or Knee
Replacement
RCT
NCT01003756
Other: Instrument
Rec
30
Adt May-10 Mar-12 DePuy
Sen
Orthopaedics
Other:
Questionnaires;
Other: RX
ACL Rupture;
Replacement
Rec
80
Adt Feb-10 Dec-11 University
Sen
Hospital, Ghent
Active,
NR
72
Sen
Oslo
Rec
95
Adt
Sen
Comp
165
Other: task oriented Total Knee
exercises
Arthroplasty
Radiation: MRI;
Procedure: Primary
Total Knee
Replacement
Other: Preoperative Osteoarthritis
neuromuscular
exercise
Effectiveness of in-home
telerehabilitation service following
knee arthroplasty
RCT
ISRCTN66285945
Effects of Kneehab 12-week Perioperative Total Knee Arthroplasty
study
NCT01096524
In-home
telerehabilitation;
face-to-face home
rehabilitation
Total knee
arthroplasty
Comp
204
Other: Standard
Physiotherapy;
Device: Kneehab
Knee Osteoarthritis;
Disuse Atrophy
Invite
200
Transfusion Requirements in
Orthopedic Surgery (PHASE 2)
NCT00726349
Other: No
intervention
Total Hip or Knee
Arthroplasty
Comp
305
280
Jul-08 Oct-11
The New
England Baptist
Hospital;
Genzyme
Adt Nov-09 Aug-11 University of
Sen
Southern
Denmark;
Odense
University
Hospital
Adt Sep-09 Aug-11 Laval University
Sen
(Canada)
Adt Mar-10 Jul-11 Bio-Medical
Sen
Research, Ltd.;
Royal Liverpool
and Broadgreen
University
Hospitals NHS
Trust
Sen
hospitalier de
l'Université de
Montréal
(CHUM)
Cost-Effectiveness of Web-Based Other: in-person;
Follow Ups
Other: web-based
NCT01079572
Arthroplasty,
Replacement, Hip;
Arthroplasty,
Replacement, Knee
Manual Lymphatic Drainage
Other: Manual
Total Knee Joint
Following Total Knee Arthroplasty lymphatic drainage; Prosthesis
Surgery
Other: relaxation
RCT, efficacy study
NCT00711711
Rec
1000 Child Feb-10 Mar-11 University of
Adt
Western Ontario,
Sen
Canada; The
Physicians'
Services
Incorporated
Foundation
Comp 60 Child Jun-08 Mar-11 Haute Ecole
Adt
Cantonale
Sen
Vaudoise de
Santé; University
of Applied
Sciences of
Western
Switzerland;
University of
Lausanne
Hospitals
Comp 75
Adt Oct-09 Mar-11 DePuy
Sen
Orthopaedics
Alignment Comparison Between
TruMatch™ Personalized
Solutions and Conventional Total
Knee Replacement
Instrumentation
efficacy study
NCT01108237
Knee Joint Icing and Kneeextension Strength
NCT01249612
Other: TruMatch™
Personalized
Solutions
Other:
Thermotherapy;
Other:
Thermotherapy
Arthroplasty
Active,
NR
20
I-ONE therapy in patients
undergoing total knee arthroplasty
RCT
ISRCTN10526056
The Efficacy of Automated
Intermittent Boluses for
Continuous Femoral Nerve Block:
a Prospective, Randomized
Comparison to Continuous
Infusions
RCT, efficacy study
NCT01226927
I-ONE therapy
(Biophysical
stimulation); usual
care post-operatively
Other: Automated
intermittent bolus
Total knee
arthroplasty
Comp
30
Arthroplasty,
Comp
Replacement, Knee;
Nerve Block
45
281
Adt Apr-10 Dec-10 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Adt Jan-08 Jun-10 IGEA (Italy)
Sen
Adt Apr-09 Apr-10 Medical
Sen
University of
South Carolina
Comparison of Functional
Outcomes of Three Surgical
Approaches in Knee Arthroplasty
NCT00983762
Early Clinical Results of MobileBearing Revision Total Knee
Arthroplasty
NCT01398800
Vanguard™ Complete Knee
System
NCT00698854
DePuy Revision TKA Implant 5yr
Survivorship
NCT01245478
Joint Stiffness Following Knee
Replacement Surgery
study
NCT00664651
Prediction of Outcomes Following
NCT01370421
Length of Stay and Complications
in High-risk Patients Receiving
Fast-track Total Hip (THA) or
Knee- Alloplasty (TKA)
NCT01515670
Knee Osteoarthritis
Term
12
Adt Jun-09 Jan-20 Massachusetts
Sen
General
Hospital;
Zimmer, Inc.
Arthroplasty,
Replacement, Knee
Rec
320 Child Jul-11 Dec-18 Colorado Joint
Adt
Replacement;
Sen
DePuy
Orthopaedics
Osteoarthritis;
Invite
600
Knee Arthroplasty
Active,
NR
0
Joint Contracture
Rec
120
Osteoarthritis
Rec
200
Arthroplasty
Complications;
Preoperative Comorbidity;
Postoperative
Morbidity
Rec
Adt Mar-04 Jan-17 Biomet, Inc.
Sen
Adt Nov-10 Dec-16 The New
Sen
England Baptist
Hospital; Depuy,
Inc.
Adt Dec-06 Dec-15 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00664651
Sen
Research
Institute
Adt Apr-11 Dec-15 Brigham and
Sen
Women's
Hospital
30000 Adt
Sen
282
Feb-10 Jan-15 Rigshospitalet, http://ClinicalTrials.gov/show/NCT01515670
Denmark;
Hvidovre
University
Hospital; Aarhus
University
Hospital; Vejle
Hospital;
Sydvestjysk
Hospital;
Holstebro
Hospital
Why Are so Many Patients
Dissatisfied With Knee
Replacement Surgery? Exploring
Variations of the Patient
Experience
NCT01466920
Analysis of Standard Versus
Barbed Sutures in Primary Total
Knee Arthroplasty.
NCT01320371
Evaluation of Weight Bearing After
Total Hip and Knee Replacement
NCT01135160
Evaluation of Patellar Crepitus
NCT01340144
Feasibility of Outpatient Total Knee
Arthroplasty
NCT01186211
150 mg/q.d. in Patients With
Moderate Renal Impairment After
Hip or Knee Replacement Surgery
NCT00847301
Preopioid Versus Nonopioid in
NCT01323179
Pain and Analgesic Consumption
Compared Between the First and
the Second Surgery in Staged
BTKRA
Prospective study
NCT01457313
Total Knee
Arthroplasty
Arthropathy of Knee
Arthroplasty,
Replacement, Hip;
Total Knee
Arthroplasty
Arthroplasty,
Replacement, Knee
Total Knee
Replacement
Not yet 500
Rec
Invite
200
Sen
British Columbia
Sen
Utah
Not yet 200 Child Aug-12 Dec-13 Kantonsspital
Rec
Adt
Münsterlingen
Sen
Active, 1250 Child Apr-11 Sep-13 Colorado Joint http://ClinicalTrials.gov/show/NCT01340144
NR
Adt
Replacement
Sen
Rec
60
Adt Nov-10 Jul-13 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01186211
Sen
Research
Institute
Arthroplasty,
Replacement;
Thromboembolism
Rec
500
Adt Apr-09 Apr-13 Boehringer
Sen
Ingelheim
Pharmaceuticals
Postoperative Pain
Rec
180
Adt Mar-11 Dec-12 Hvidovre
Sen
University
Hospital
Degenerative
Arthritis
Rec
30
Adt Oct-11 Nov-12 Seoul National
Sen
University
Bundang
Hospital
283
Changes of the Single Limb
Standing Balance After Total Knee
Arthroplasty in Degenerative
Osteoarthritis
NCT01192334
Comparison of Clinical Outcomes
and Performance of Total Knee
Replacement Patients Before and
After Surgery
NCT01379118
Perioperative Hyperglycaemia in
Replacement
NCT01021826
Comparison of Kinematics for
Subjects Implanted With a PFC
Sigma Rotating Platform or Fixed
Bearing Total Condylar III
Prothesis
study
NCT01290640
In Vivo Determination of 3D
Patellofemoral Mechanics
NCT01290627
Prospective Study Measuring
Clinical Outcomes of Knee
Arthroplasty Using the
OrthoSensor Surgical Smart Trial
NCT01469299
Preoperative Pain, Function, and
Activity for Total Hip and Knee
Arthroplasty Patients
NCT01248039
Knee Osteoarthritis
Rec
50
Degenerative Joint Not yet 50
Disease;
Rec
Injury, Trauma;
Connective Tissue
Disorder; Pain; Loss
of Function
Knee Replacement; Active, 200
Hip Replacement;
NR
Hyperglycemia
Knee Prosthesis;
Knee Arthroplasty
Not yet
Rec
30
Arthoplasty
Replacement Knee;
Knee Prosthesis
Not yet
Rec
40
Rec
500
Arthroplasty
Rec
100
284
Child Sep-10 Oct-12 Ulsan University http://ClinicalTrials.gov/show/NCT01192334
Adt
Hospital
Sen
Adt
Sen
Jul-11 Oct-12 Loma Linda
University
Adt Dec-09 Jul-12 Coxa, Hospital http://ClinicalTrials.gov/show/NCT01021826
Sen
for Joint
Replacement;
University of
Tampere
Adt Feb-11 Feb-12 The University of http://ClinicalTrials.gov/show/NCT01290640
Sen
Tennessee
Knoxville; DePuy
Orthopaedics
Adt Feb-11 Feb-12 The University of http://ClinicalTrials.gov/show/NCT01290627
Sen
Tennessee
Knoxville; DePuy
Orthopaedics
Adt Oct-11 Jan-12 Orthosensor,
Sen
Inc.
Sen
University
Hospital;
Lundbeck
Foundation
Study of Surgical Technique With
Use of Single-radius Prosthesis in
NCT01505452
Surgical Field Bacterial
Contamination in Primary Total Hip
(THA) and Knee (TKA)
Arthroplasty
NCT01493375
Arthritis of Knee
Tissue Culture Versus Swab
Culture in Prosthetic Joint
Infections
NCT01482533
Systemic Inflammation Versus
Acute Pain in Total Knee
Arthroplasty (TKA)
NCT01322074
A Comparison of Wear Among
Mobile and Fixed Bearing Knee
Replacements
study
NCT01165957
Postoperative Sleep Disturbances
Role in Cognitive Test Results
After Fast-track Hip and Knee
Arthroplasty
Prospective study
NCT01383369
Comparison of Stability and
Outcomes in Single-radius
Femoral Component for Total
Knee Arthroplasty
NCT01379755
Revision Total Hip
Not yet N/K
Arthroplasty;
Rec
Revision Total Knee
Arthroplasty
Prosthetic Infections
Rec
30
Comp
60
Adt Nov-11 Jan-12 Athens
Sen
Orthopedic
Clinic, P.A.;
Stryker
Orthopaedics
Adt Jun-10 Dec-11 Northern
Sen
Orthopaedic
Division,
Denmark;
Aarhus
University
Hospital;
University of
Aarhus; Aalborg
University
Adt
N/K Nov-11 Rothman
Sen
Institute
Orthopaedics
Other Acute
Comp
Postoperative Pain;
Systemic
Inflammatory
Response Syndrome
Osteoarthritis
Invite
120
Adt Aug-09 Oct-11 Hvidovre
Sen
University
Hospital
26
Adt Jun-10 Oct-11 Anderson
Sen
Orthopaedic
Research
Institute; DePuy
Orthopaedics
Postoperative
Cognitive Abilities
Comp
20
Adt Feb-11 Aug-11 Rigshospitalet,
Sen
Denmark
Osteoarthritis
Active,
NR
213
Adt Aug-10 Jul-11 Chonnam
Sen
National
University
Hospital
285
Comp 5476 Adt Feb-09 Jul-11 Boehringer
Sen
Ingelheim
Pharmaceuticals
220 mg/q.d. in the General
Population After Hip or Knee
Replacement Surgery
NCT00846807
NCT01144000
Arthroplasty,
Replacement;
Thromboembolism
Effect of Rivaroxaban on
Coagulation Parameters- an ex
Vivo Study
NCT00986635
Differences in
Comp 100
Laboratory
Coagulation
Parameters; hip or
knee replacement
surgery
Effect of Dabigatran Comp 70
in Laboratory
Coagulation
Parameters; hip or
knee replacement
surgery
Total Knee
Not yet 40
Replacement
Rec
Effect of Dabigatran on
Coagulation parameters-an ex
Vivo Study
NCT01112202
Biochemical Approach to
Measuring Surgical Trauma
NCT01037400
VISIONAIRE™ Value Study
NCT01107769
Recovery at the Post Anaesthetic
Care Unit After Hip and Knee
Arthroplasty
NCT01178489
Staphylococcal
Not yet
Infections;
Rec
and shoulder
Prosthetic Joint
Infection (PJI)
60
Sen
Hospitalier
Universitaire
Vaudois;
University of
Lausanne
Hospitals;
Kantonsspital
Liestal;
Schulthess Klinik
Adt Sep-09 Apr-11 Johann
Sen
Wolfgang
Goethe
University
Hospitals
Adt Apr-10 Apr-11 Johann
Sen
Wolfgang
Goethe
University
Hospitals
Adt Feb-10 Feb-11 Hamilton Health http://ClinicalTrials.gov/show/NCT01037400
Sen
Sciences
Corporation
Knee
Comp
38
Adt Apr-10 Feb-11 Smith &
Sen
Nephew, Inc.
PACU Stay After
THA Under Spinal
Anaesthesia; PACU
Stay After TKA
Under Spinal
Anaesthesia
Comp
170
Adt Aug-10 Jan-11 Hvidovre
Sen
University
Hospital
286
Why in Hospital - Factors
Determining Time to Discharge
Readiness After Arthroplasty
Surgery
NCT01047371
Early Outcome Assessment of
Revision Total Knee Arthroplasty
Using Metaphyseal Sleeves
NCT01156558
Early Migration in a High
Congruent Rotating Platform Total
Knee Prosthesis Design
NCT01102829
Study to Evaluate the Safety and
Efficacy of Pradaxar for the
Thromboembolism in the Mexican
Population Undergoing Elective
Surgery
NCT00967447
Pain; Nausea;
Comp
Vomiting; Dizzyness;
Fatigue;
Organizational
Concerns; Ect.;
Arthroplasty, Hip;
Arthroplasty, Knee
Revision Total Knee Comp
Replacement
200
Comp
11
Thromboembolism;
Arthroplasty,
Replacement, Hip
Term
Adt Jan-10 Aug-10 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Adt Jun-10 Jul-10 Rothman
Sen
Institute
Orthopaedics;
DePuy
Orthopaedics
Child Sep-07 Apr-10 Leiden
Adt
University
Sen
Medical Center
Adt Feb-09 Mar-10 Boehringer
Sen
Ingelheim
Pharmaceuticals
287
A9G: OTHER
Title
CT ID
Behavioural
Early Intervention for Adolescents
With Patellofemoral Pain
Syndrome
RCT, efficacy study
NCT01438762
Interventions
Conditions
Behavioral: Patient
information and
education; Other:
Information,
education and
physiotherapy
Patellofemoral Pain
Syndrome
Rec
Gait Retraining to Reduce Knee
Osteoarthritis Pain
study
NCT01397981
Supporting Decision Making for
Musculoskeletal PreferenceSensitive Care
RCT
NCT01345123
Behavioral: Gait
retraining
Rec
Behavioral: Provision Knee Pain Chronic;
of condition specific Arthritis (Hip);
DVD and Pamphlet Arthritis (Knee);
to support Shared
Back Pain
Decision Making;
Behavioral:
Telephonic outreach
and support by
Health Coach;
Behavioral: No
condition specific
telephonic outreach
Educational Intervention for Knee Behavioral: Decision Osteoarthritis
Pain
Aid Video;
RCT, efficacy study
Behavioral:
NCT00324857
Motivational
Interviewing
Recruit
n
Age Start
(Grp) Date
End Sponsors
Date
URL
102 Child Jun-11 Sep-14 Michael Skovdal http://ClinicalTrials.gov/show/NCT01438762
Adt
Rathleff;
University of
Southern
Denmark;
Aarhus
University
Hospital
25
Adt Jul-11 May-12 Stanford
Sen
University
Active, 1800 Adt Feb-11 Mar-12 Health Dialog;
NR
0
Sen
Foundation for
Informed
Medical Decision
Making;
University of
Massachusetts,
Boston
Comp
600
288
Adt Sep-06 Sep-11 Department of http://ClinicalTrials.gov/show/NCT00324857
Sen
Veterans Affairs
Device
iUni Foundation Study
study
NCT01117571
Gold Against Pains From
Osteoarthrosis in the Knee
NCT00378339
Study of IN.PACT Amphirion™
Drug Eluting Balloon vs. Standard
PTA for the Treatment of Below
the Knee Critical Limb Ischemia
NCT00941733
Research in Osteoarthritis in
Manchester (ROAM) Brace
RCT
ISRCTN50380458
Hymovis™ Versus Placebo in
Knee Osteoarthritis
study
NCT01372475
Compass Hinge Stabilization of
Knee Dislocations: A Randomized
Trial
RCT, efficacy study
NCT00582517
Device: iUni®
Unicompartmental
Knee Resurfacing
Device
Osteoarthritis
Device: gold berlocks Arthritis
Device: IN.PACT
Amphirion; Device:
Standard PTA
balloon
Chronic Critical Limb
Ischemia
Brace
Patellofemoral pain
Device: Hymovis
Knee Osteoarthritis
Intra-articular
Phosphate Buffered
Saline Injection
Device: Compass
Knee Dislocation
Universal Hinge
External Fixator;
Procedure: Noninvasive External
Knee Brace
Effectiveness Study of the Ivivi
Device: Ivivi
Knee Osteoarthritis
SofPulse for Pain Amelioration in SofPulse; Device:
Adults With Mild to Moderate Knee Ivivi SofPulse
Osteoarthritis
NCT01457742
Rec
200
Adt Apr-10 Dec-20 ConforMIS, Inc. http://ClinicalTrials.gov/show/NCT01117571
Sen
Wdrwn
50
Rec
357
Sen
Orthopaedic
Division,
Denmark;
University of
Aarhus; Aarhus
University
Hospital
Adt Sep-09 Dec-15 Invatec S.p.A.
Sen
Active
144
Adt Aug-09 Mar-13 University of
Manchester (UK) trials.com/ISRCTN50380458
Rec
800
Adt Mar-11 Jan-13 Fidia
Sen
Farmaceutici
s.p.a.
Active,
NR
109
Sen
Alabama at
Birmingham;
Smith &
Nephew, Inc.
Rec
150
Adt Oct-11 Oct-12 Amp
Sen
Orthopedics, Inc.
289
The Efficacy of
Device: Synvisc One Knee Osteoarthritis
Viscosupplementation for Early
Knee Osteoarthritis
RCT
NCT01210742
A Study Comparing
Device: Hylan G-F Osteoarthritis, Knee
Viscosupplementation and
20 (Synvisc One);
Corticosteroid Injections for Knee Drug:
Osteoarthritis
Methylprednisolone
RCT, efficacy study
(Corticosteroid)
NCT01132677
Investigation of Sodium
Device: Sodium
Hyaluronate for Treatmet of Painful Hyaluronate; Device: Knee
Chronic Osteoarthritis of the Knee Buffered Saline
study
NCT00988091
Negative Pressure Wound
Device: V.A.C. by
Surgical Wound
Dressing Study
K.C.I.
Infection
RCT, efficacy study
NCT01366105
The effectiveness of Shoes and
Barefoot walking;
Medial knee OA
Insoles on the Loading at the Knee Mobility shoe
in subjects with knee osteoarthritis designed to mimic
RCT
barefoot walking;
ISRCTN83706683
Control shoe; Control
shoe with
unsupported lateral
wedge; Control shoe
with salford wedge
Position HTO Multicenter NIS
Device: Position
Medial
HTO system
Monocompartmental
NCT00889304
Knee
Safety and Effectiveness Study of Device: MONOVISC Osteoarthritis
Hyaluronic Acid for Osteoarthritis
of the Knee
NCT00653432
Not yet
Rec
60
Adt Dec-10 Oct-12 University of
Sen
Oxford
Invite
78
Adt May-10 Dec-11 LifeMark Health http://ClinicalTrials.gov/show/NCT01132677
Sen
Comp
596
Adt Sep-09 Apr-11 Ferring
Sen
Pharmaceuticals
Comp
106
Adt Aug-08 Oct-10 Georgetown
Sen
University
Comp
50
Sen
Salford (UK)
Comp
221
Adt
Sen
Jul-07 Jun-10 Aesculap AG
Comp
350
Adt Jan-08 Feb-10 Anika
Sen
Therapeutics,
Inc.
290
Dietary supplement
Zurich Multiple Endpoint Vitamin D Dietary Supplement: Knee Osteoarthritis
Trial in Knee OA Patients
Vitamin D3
(cholecalciferol)
NCT00599807
Effect of Gabapentin on
Orthopedic Pain
NCT01546857
Clonidine in Femoral Nerve Block
Surgery in Children
study
NCT01293149
Biological Response of Stage IV
Knee Osteoarthritis to Serial
12.5% Dextrose
Phase II/III: Single group
NCT01210183
Effectiveness of Two Types of
Treatment in Restoring Muscle
After Hip or Knee Surgery
NCT00393848
Safety, Tolerability and
Pharmacokinetics of SAR113945
in Japanese Patients With Knee
Osteoarthritis
NCT01511549
Drug: Placebo; Drug: Degenerative Joint
Gapabentin
Disease of Hip and
Knee.
Drug: Ropivacaine;
Drug: Clonidine
Other
Reconstructive
Surgery
Drug: Dextrose
intraarticularly
administered
Knee Osteoarthritis
Drug: Essential
amino acid
supplement; Drug:
Ketoconazole; Drug:
Whey protein
Hip Fracture;
Osteoarthritis;
Femur Head
Necrosis
Drug: placebo; Drug: Knee Osteoarthritis
SAR113945
Rec
287
Adt Jan-08 May-14 University of
Sen
Zurich; Harvard
School of Public
Health; Tufts
University;
Boston
University
Rec
90
Sen
Medicine and
Dentistry New
Jersey
Not yet 150 Child Apr-11 Mar-13 Nationwide
Rec
Adt
Children's
Hospital
Rec
12
Adt
Sen
Active,
NR
120
Rec
24
Sen
Arkansas;
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Adt Jan-12 Sep-12 Sanofi-Aventis http://ClinicalTrials.gov/show/NCT01511549
Sen
291
Jul-10 Dec-12 Universidad
Nacional de
Rosario
Evaluation of the Effect of Adding Drug: Hylan GF-20
Corticosteroid to
alone; Drug:
Viscosupplementation
Triamcinolone
study
NCT01335321
TArgeting Synovitis in Knee
osteoarthritis (OA)
efficacy study
ISRCTN07329370
Study of Viscosupplementation for
the Treatment of Knee Pain After
Menisectomy
RCT, efficacy study
NCT00971074
The Efficacy and Safety of
Intraarticular Sodium Hyaluronate
(Hyalgan) After Proximal Tibial
Osteotomy in Treatment of Knee
Osteoarthritis Patients
study
NCT01267214
Safety, Tolerability and
Pharmacokinetics of SAR113945
Following Intra-articular
Administration in Patients With
Knee Osteoarthritis
NCT01113333
Osteoarthritis
Aspiration + injection Knee Osteoarthritis
80mg methylprednisolone acetate
(Depo-Medrone).
Drug: Hylan G-F 20; Arthralgia
Drug: Sham Injection
Drug: Sodium
Hyaluronate
(Hyalgan); Other:
Osteotomy alone
Knee Osteoarthritis
Drug: placebo; Drug: Osteoarthritis
SAR113945
Rec
108
Active
120
Rec
252
Adt Dec-09 Dec-11 Ohio State
University;
Genzyme
Comp
40
Adt Feb-09 Jul-11 TRB Chemedica http://ClinicalTrials.gov/show/NCT01267214
Comp
40
Adt Apr-10 Feb-11 Sanofi-Aventis
Sen
292
Adt Mar-11 Jul-12 University of Sao http://ClinicalTrials.gov/show/NCT01335321
Sen
Paulo General
Hospital;
FundaÃ§Ã£o de
Amparo Ã
Pesquisa do
Estado de SÃ£o
Paulo
Adt May-10 May-12 Salford Royal
NHS Foundation trials.com/ISRCTN07329370
Trust (UK)
Device: Focused
Epicondylitis;
Tendinopathies
Topical NO;
study
Behavioral: Painful
NCT01185951
Achilles
tendinopathy;
Behavioral: Painful
on 25° decline board;
Behavioral: Painful
elbow tendinopathy
using Thera-Band
Flex-Bar
Procedure
Oxford Partial Knee Comparative
Instrument Pilot Study
assignment
NCT01410786
Optimisation of the Treatment of
Infectious Bursitis
study
NCT01406652
A Comparison of Manual Physical
Therapy and Corticosteroid
Injections for Knee Osteoarthritis
RCT, efficacy study
NCT01427153
Active,
NR
114
Procedure:
Conventional
Rec
Instrumentation;
Procedure: Signature
Custom Guides
Procedure: TwoOlecranon Bursitis;
Rec
240
stage bursectomy
Patellar Bursitis
Procedure:
Orthopaedic manual
physical therapy;
Procedure:
Corticosteroid
Injection
Comparison of Autologous
Procedure:
Chondrocyte Implantation Versus Autologous
Mosaicoplasty: a Randomized Trial chondrocytes
transplantation;
NCT00560664
Procedure:
Mosaicoplasty
Knee Osteoarthritis
Not yet 156
Rec
Knee Chondral or
Osteochondral
Defect
Active,
NR
76
293
Sen
Medical School
Adt Apr-12 Oct-14 Biomet, Inc.
Sen
Adt May-11 Jun-14 University
Sen
Hospital,
Geneva
Adt Aug-11 Sep-13 Madigan Army http://ClinicalTrials.gov/show/NCT01427153
Sen
Medical Center;
Brooke Army
Medical Center;
Wilford Hall
Medical Center
Adt Apr-07 Dec-12 University
Hospital, Brest;
Institut National
de la Santé Et
de la Recherche
Médicale,
France
Randomized Control Trial on
Postoperative Weight Bearing
After High Tibial Osteotomy (HTO)
NCT00799370
Allogeneic Vascularized Knee
Transplantation
NCT01133145
Procedure: Early
weight bearing;
Procedure: Delayed
weight bearing
Procedure: knee joint Osteitis; Limb
transplantation
Salvage; Joint
Deformities,
Acquired; Skin
Transplantation;
Bone
Transplantation
Evaluation of Optimal Dose of
Procedure: PC-FNB Arthropathy of Knee
Local Anesthetics for Patient
with basal
Joint
Controlled Continuous Femoral
administration of
Nerve Block
local anesthetics;
RCT, efficacy study
Procedure: PC-FNB
NCT01198340
without basal local
anesthetics
Follow-up of Patients After Knee Procedure: History Knee Arthrodesis
Arthrodesis With an Intramedullary taken and clinical
With Intramedullary
Nail
examination
Nail
efficacy study
NCT00284297
Restricted vs. Free Knee Range Of Procedure: Locked Patellar Dislocation
Motion For Primary Traumatic
knee brace;
Patellar Dislocation
Procedure: Locked
RCT
knee brace
NCT01344915
A Prospective Randomized Study Procedure:
Patella-Dislocation;
of Medial Patellofemoral Ligament Patellofemoral
Patellofemoral
(MPFL) Reconstruction
stabilizing surgery
Osteoarthritis;
RCT
Patellar Instability
NCT00816647
Rec
136
Adt Nov-08 Nov-12 Hospices Civils
de Lyon
Invite
6
Adt
Rec
60
Adt Sep-10 Jun-12 Okayama
Sen
University
Rec
20
Adt Sep-05 Aug-11 University
Sen
Hospital, Ghent
Active,
NR
Term
Jun-12 University of
Jena
Adt Dec-05 Jun-11 Tampere
University
Hospital
50
294
Adt Dec-08 Jun-11 Finnish Defense http://ClinicalTrials.gov/show/NCT00816647
Forces;
Tampere
University
Hospital,
Department of
Musculosceletal
Diseases
Patellar Tendon Regeneration
With Platelet-rich Plasma
NCT01111747
Procedure: Platelet- Knee Instability
rich plasma;
Procedure: Control
group
Active,
NR
27
Hyperpronation and Foot-pains
NCT00736138
Procedure: training
and pellots
Comp
50
Rec
72
Active,
NR
20
Comp
43
Comp
40
Active,
NR
76
Arthrosis in Knee
Local Analgesia in Knee- and
Procedure: Position Rheumatoid Arthritis;
Hipatroplastic Surgery in Patients of catheter
Orthopedic Surgery;
With Rheumatic Disease: ExtraAnalgesia
vs. Intracapsulare Position of
Catheter
RCT, efficacy study
NCT01050738
Weightbearing After High Tibial
Procedure: Unlimited Osteoarthritis, Knee
Osteotomy
postoperative
weightbearing
NCT00426907
Outcome After Soft Tissue
Procedure:
Patella Dislocation
Realignment of the Tibial Insertion Medialising insertion
of the Patella Tendon
of patella tendon
NCT01059721
Results of Opening-wedge High
Procedure: Iliac crest Genovarum
Tibial Osteotomy Using Iliac Crest allograft; Procedure:
Allograft Compared to Iliac Crest Iliac crest autograft
Autograft
Phase III: RCT
NCT00595712
Comparison of Autologous
Procedure:
Knee Chondral or
Chondrocyte Implantation Versus Autologous
Osteochondral
Mosaicoplasty: a Randomized Trial chondrocytes
Defect
transplantation;
NCT00560664
Procedure:
Mosaicoplasty
295
Child Nov-08 Dec-10 University of Sao http://ClinicalTrials.gov/show/NCT01111747
Adt
Paulo General
Hospital;
Instituto de
Ortopedia e
Traumatologia HCFMUSP SÃ£o Paulo,
Brazil
Sen
Orthopaedic
Division,
Denmark
Child Jan-10 Aug-10 Spenshult
Adt
Hospital
Sen
Adt
Jan-07 Aug-10 Northern
Orthopaedic
Division,
Denmark
Child Jan-10 Jul-10 Medical
Adt
University of
Graz
Child Sep-07 Feb-10 Tehran
Adt
University of
Medical
Sciences
Adt
Apr-07 Dec-12 University
Hospital, Brest;
Institut National
de la Santé Et
de la Recherche
Médicale,
France
Oxford Partial Knee Comparative
Instrument Pilot Study
assignment
NCT01410786
Optimisation of the Treatment of
Infectious Bursitis
study
NCT01406652
Other
Functional and Quality of Life
Outcomes Following
Viscosupplementation for Knee
Osteoarthritis
NCT01447303
Shared Decision Making in
Patients With Osteoarthritis of the
Hip and Knee
RCT
NCT01492257
Structured Non-operative
Treatment of Knee Osteoarthritis
RCT, efficacy study
NCT01535001
Procedure:
Conventional
Rec
Instrumentation;
Procedure: Signature
Custom Guides
Procedure: TwoOlecranon Bursitis;
Rec
240
stage bursectomy
Patellar Bursitis
Adt Apr-12 Oct-14 Biomet, Inc.
Sen
Adt May-11 Jun-14 University
Sen
Hospital,
Geneva
Other: Subject
Knee Osteoarthritis
outcomes following
viscosupplementatio
n of the knee
Rec
500
Sen
Florida
Other: Shared
Decision Making
Intervention
Hip Osteoarthritis;
Knee Osteoarthritis
Rec
120
Adt
Sen
Other:
Neuromuscular
training (NEMEXTJR); Behavioral:
Information; Drug:
Paracetamol; Drug:
Burana; Drug:
Pantoprazole;
Behavioral: Dietary
counseling;
Behavioral: Patient
education; Other:
Insoles
Knee
Not yet 100
Rec
296
Jul-11
California, San
Francisco;
Stanford
University;
Robert Wood
Johnson
Foundation
Adt Feb-12 Mar-14 Northern
Sen
Orthopaedic
Division,
Denmark
Effectiveness of a Knee Brace
When Combined With
Viscosupplementation in the
Treatment of Knee Osteoarthritis
RCT, efficacy study
NCT01478386
Rec
150
Adt Dec-11 Jan-14 OAD
Sen
Orthopaedics
Not yet
Rec
70
Adt Jun-11 Sep-13 St. Michael's
Sen
Hospital,
Toronto
Knee Osteoarthritis
Rec
284
Adt Feb-12 Sep-13 Central Hospital, http://ClinicalTrials.gov/show/NCT01544647
Sen
Nancy, France
Knee Degenerative
Disease; Knee
Arthrosis; Knee
Osteoarthritis;
Rec
12
Adt May-10 Jun-13 Red de Terapia http://ClinicalTrials.gov/show/NCT01183728
Sen
Celular, Spain
Knee Osteoarthritis
Rec
80
Active,
NR
15
Sen
Zurich;
Kantonsspital
Olten;
Kantonsspital
Aarau; Lund
University;
Maastricht
University
Adult Jan-09 Aug-12 RTI Biologics
Other: Orthovisc;
Knee Osteoarthritis
Device: DonJoy HA
lite knee brace;
Device: Orthovisc
injections and
DonJoy HA lite knee
brace
Other: Early
Traumatic Knee
Physiotherapy start Dislocation
Late Compared to Early
Physiotherapy Following Knee
Dislocation
Phase III: RCT
NCT01296750
Spa Therapy in Knee
Other: Usual spa
Osteoarthritis (OA): Nancy-thermal protocol; Other:
RCT, efficacy study
Active spa protocol
NCT01544647
Treatment of Knee Osteoarthritis Other: Autologous
With Autologous Mesenchymal
bone marrow
Stem Cells
mesenchymal stem
cells (MSV)
study
NCT01183728
Effect of Pre-surgery
Other: preoperative
Neuromuscular Physiotherapy
neuromuscular
(PT)
training; Behavioral:
knee OA School
NCT00913575
Evaluation of the CR Plug for
Other: CR Plug
Repair of Defects Created at the
Harvest Site From an Autograft in
the Knee.
NCT00821873
Knee Injury
297
An Analysis of Potential Sex
Other:
Differences in Knee Osteoarthritis musculoskeletal
NCT01403207
Degenerative Joint
Disease;
Osteoarthritis
Evaluation of the Composite of
Other: Primary injury Knee Injury
Cancellous and Demineralized
site; Other: Backfill
Bone Plug (CR-Plug) for Repair of site
Osteochondral Defects in the Knee
study
NCT00984594
Comparing Manipulation,
Other: Full Kinetic
Rehabilitation and Combination of Chain Manipulative
the Two in the Treatment of Knee Therapy; Other: Full
Osteoarthritis
Kinetic Chain
Rehabilitation; Other:
NCT01188837
Full Kinetic Chain
Manipulative
Therapy with
Rehabilitation
Moxibustion for Knee
Other: Moxibustion Idiopathic
Osteoarthritis
treatment plus usual Osteoarthritis
Phase I/II: RCT, safety/efficacy care; Other: Usual
study
care alone group
NCT01354860
The Effects of Topical Calcium
Other: Topical
Wound Healing;
Glycerophosphate on Surgical
calcium
Scarring
Wound Healing and Residual
glycerophosphate
Scarring
lotion
RCT, efficacy study
NCT01264588
Rec
20
Active,
NR
20
Rec
144
Adt Sep-10 Oct-11 Cleveland
Sen
Chiropractic
College; Durban
University of
Technology
South Africa;
Murdoch
University
Comp
40
Adt Dec-10 May-11 Korea Institute of http://ClinicalTrials.gov/show/NCT01354860
Sen
Oriental
Medicine
Comp
20
Adt Apr-08 Dec-10 AkPharma Inc.; http://ClinicalTrials.gov/show/NCT01264588
Sen
Rothman
Institute
Orthopaedics;
Texas Tech
University Health
Sciences
Center;
cyberDERM
Clinical Studies;
Bacharach
Institute for
Rehabilitation
298
Adt Aug-11 Jul-12 Mary O'Connor; http://ClinicalTrials.gov/show/NCT01403207
Sen
Society of
Women's Health
Research;
University of
Calgary; Florida
State University;
Georgia Institute
of Technology
Adult Jan-09 May-12 RTI Biologics
Enhancing the Effectiveness of
Physical Therapy for People With
Knee Osteoarthritis
NCT01314183
Effect of Mobilization on Acute
Postoperative Pain and
Nociceptive Function
study
NCT01018277
Osteoarthritis
Not yet 300
Rec
Adt
Sen
Other: Mobilization
(walking)
Pain Sensitivity,
Postoperative
Comp
26
Adt Dec-09 Jun-10 Hvidovre
Sen
University
Hospital;
Lundbeck
Foundation
Joint Disease
Wdrwn
0
Adt Dec-09 Jun-23
Sen
OA Knee
Rec
5000 Adt Sep-01 Dec-20 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00261066
Sen
Research
Institute
Pain; Arthritis
Invite
200
Adt Mar-09 Dec-18
Sen
Osteoarthritis, Knee; Rec
Osteonecrosis
148
Adt
Sen
Healthy; Medial
Patellofemoral
Ligament
Reconstruction
50
Adt May-10 May-15
Sen
Microplasty Tibial Tray Data
Collection
NCT00754637
Outcome Following Orthopaedic
Surgery
NCT00261066
Regenerex Tibial Tray Multi-Center
Data Collection
NCT00859963
Treatment of Medial
Compartmental Osteoarthritis
Grade 1-4 (According to KellgrenLawrence) or Osteonecrosis With
TomoFix™ Small or
Conservatively
NCT01048710
Medial Patellofemoral Ligament
Reconstruction: A Review of
Technique, Accuracy, and
Outcome
NCT01405729
Invite
299
N/K
Nov-10 Agency for
Healthcare
Research and
Quality (AHRQ)
Other: Exercise;
Other: manual
therapy
Jul-09 Feb-16
Biomet, Inc.
Biomet, Inc.
AO Clinical
Investigation and
Documentation;
Synthes Inc.
University of
Utah
Creating a Tissue Bank of Knee
Capsules
NCT01320124
Osteoarthritis; Knee Rec
Joint Contractures
Monitoring of Acute Knee Injuries
to Understand Osteoarthritis
Development
NCT01382173
Chronic Knee Pain Study
NCT00776932
Traumatic Knee
Injury; Knee
Osteoarthritis
Knee Osteoarthritis Active,
NR
522
Assessment of Blood Loss With a
Point Of Care Device
NCT01430273
Acute Arthropathy of Rec
Knee, Patella, Tibia,
or Fibula
200
The Parapatellar Approach to
Intramedullary Tibial Nailing
NCT01407718
Efficiency of Patellar Taping in
Treatment of Patellofemoral Pain
Syndrome
NCT01504100
Characterizing Knee Pain and
Response to Surgery Using Local
Biomarkers
NCT00961623
Validation of an Online Knee Pain
Map and Questionnaire: A
Probabilistic Diagnostic Tool
NCT01492244
Knee Pain
Intermittent
60
Not yet
Rec
Active,
NR
1500 Adt Mar-11 Dec-14 Ottawa Hospital http://ClinicalTrials.gov/show/NCT01320124
Sen
Research
Institute;
Canadian
Institutes of
Health Research
600 Child Sep-11 Jan-14 Lund University http://ClinicalTrials.gov/show/NCT01382173
Adt
Adt Jun-07 Jun-13
Sen
University of http://ClinicalTrials.gov/show/NCT00776932
Pittsburgh;
National
Institutes of
Health
Adt Jul-11 Aug-12
Assistance
Sen
Paris; Ministry of
Health, France
Adt Jun-10 Jul-12
University of http://ClinicalTrials.gov/show/NCT01407718
Sen
Utah
Patellofemoral Pain Rec
Syndrome
100
Adt May-11 May-12 National Taiwan http://ClinicalTrials.gov/show/NCT01504100
University
Hospital
Inflammation
Rec
150
Adt
Sen
Knee Pain
Rec
1000 Adt Dec-11 Dec-11
Sen
300
Jul-09 Dec-11
Stanford
University
Brock Foster;
TMT Medical
Incorporated
The Effects of Bariatric Surgery
Weight Loss on Knee Pain in
Patients With Osteoarthritis of the
Knee
NCT00752765
Evaluation of Ultrasonic Neuroma
Size With Residual Limb Pain in
Above-Knee Amputees
Cross-sectional, case-only study
NCT00686764
Knee Pain; Knee
Osteoarthritis
Rec
30
Adt Sep-08 Sep-10
Sen
Penn State
University
Neuroma
Amputation
Comp
7
Adt May-08 Feb-10 Oregon Health
Sen
and Science
University
Interventions
Conditions
Recruit
n
Drug: Botulinum
Toxin (Type A)
injection (10 U/Kg)
Clubfoot
Drug: Botox
Idiopathic Clubfoot
(Talipes
Equinovarus)
Active,
NR
36
Child Sep-05 Feb-13 University of
British Columbia
Drug: Botox
Idiopathic Clubfoot
(Talipes
Equinovarus)
Active,
NR
50
Child Sep-05 Dec-12 University of
British Columbia
6764
A10. FOOT AND ANKLE
A10A: PAEDIATRICS
Title
CT ID
Using Botox to Treat Patients With
Idiopathic Clubfoot
efficacy study
NCT00474032
A Double-Blind, Randomized
Control Trial Comparing Botulinum
Toxin Type A (Botox) and Placebo
in the Treatment of Idiopathic
Clubfoot
RCT, efficacy study
NCT00152347
Efficacy of Botox in Patients With
Idiopathic Clubfoot
efficacy study
NCT00152334
Rec
Age Start
(Grp) Date
End Sponsors
Date
URL
2000 Child Mar-03 Mar-23 University of
British Columbia
301
Pharmacokinetic of
levobupivacaïne After Sciatic
Nerve Block in Children
assignment, pharmacokinetics
study
NCT00682344
CLONidine and ROPivacaine in
peripheral nerve blocks in children
RCT, efficacy study
ISRCTN90832436
Botox Clinical Trial
Phase IV: RCT
NCT00624299
Botulinum toxin: an adjunct in limb
reconstruction - Can it reduce pain
and joint complications in the
lengthening phase?
RCT
ISRCTN35609758
Drug:
Levobupivacaïne
Surgical Pathology
of the Leg or the
Foot.
Rec
27
Child Jan-08 Jul-12 Assistance
Publique
Hopitaux de
Marseille
Isotonic saline;
Clonidine; Clonidine
plus 0.2%
Ropivacaine
Drug: Botox; Other:
Saline
Disturbances of
Achilles tendon and
club foot
Comp
77
Leg Length
Inequality; Foot
Deformities
Limb reconstruction
surgery; femoral or
tibial deformity;
congenital talipes
equinovarus
Not yet
Rec
36
Comp
36
Child Jan-09 May-10 General
http://www.controlledChildren's
Hospital
(Greeece)
Child Mar-08 May-10 Sheffield
Children's NHS
Foundation Trust
Child Apr-08 Apr-10 Sheffield
http://www.controlledChildren's NHS trials.com/ISRCTN35609758
Foundation Trust
(UK)
Botulinum toxin
intramuscular
injections; Saline
injections
Economic Evaluation of Clubfoot
Treatment: One Centre's
Experience
NCT00475631
Pedobarographic Assessments of
Clubfoot Treated Patients
NCT00175708
Outcomes of Compliance With
Brace Wear in Clubfoot
NCT01481324
Clubfoot
Rec
600 Child Oct-03 Dec-23 University of
British Columbia
Clubfoot
Rec
100 Child Sep-05 Dec-11 University of
British Columbia
Clubfoot
Rec
70
302
Child Oct-09 Nov-11 Shriners
Hospitals for
Children; Kosair
Charities, Inc.
Title
CT ID
Behavioural
A trial comparing weight bearing to
non-weight bearing following ankle
fracture fixation
RCT
ISRCTN33416471
Early Weightbearing and
Mobilization Versus NonWeightbearing and Mobilization in
Unstable Ankle Fractures
RCT, efficacy study
NCT01196338
Device
Tightrope or Screw Fixation of
Acute Tibiofibular Syndesmotic
Injury
RCT, efficacy study
NCT01275924
Foot and Ankle Range of Motion
(Stretching) Apparatus
RCT, efficacy study
NCT00527748
Foot and Ankle Range of Motion
(Stretching) Apparatus
RCT, efficacy study
NCT00527748
Interventions
Conditions
Weight-bearing; non- Closed ankle
weight-bearing
fractures
Behavioral: Early
weight-bearing and
range of motion
exercises;
Behavioral: nonweight bearing, no
range of motion
Ankle Injuries
Recruit
n
Active
76
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt Jan-11 Dec-13 St George's
Healthcare NHS trials.com/ISRCTN33416471
Trust (UK)
Rec
110 Child Sep-10 Jun-12 University of
Adt
Toronto;
Sen
Orthopaedic
Trauma
Association;
Canadian
Orthopaedic
Foundation;
Künzli
SwissSchuh
Device: Tightrope
Syndesmotic Injury
Syndesmosis Repair of the Ankle
Kit; Device:
Syndesmotic screw
Rec
100
Adt Jan-11 Dec-14 Sykehuset Asker http://ClinicalTrials.gov/show/NCT01275924
Sen
og Baerum; Oslo
University
Hospital
Device: NonMeasuring Ankle
Exerciser (Ankle
Recovery
Mechanism)
Device: NonMeasuring Ankle
Exerciser (Ankle
Recovery
Mechanism)
Plantar Fasciitis;
Flatfoot; Calcaneus
Fractures
Rec
100
Sen
MissouriColumbia
Plantar Fasciitis;
Flatfoot; Calcaneus
Fractures
Rec
100
Sen
MissouriColumbia
303
Prospective Study on Artelon®
Device: Artelon
Tissue Reinforcement in Repair of
Chronic Ruptures and Re-ruptures
of the Achilles Tendon
NCT01237613
Compression Treatment Effects on Device: Intermittent
Complications and Healing of
pneumatic
Achilles Tendon Rupture
compression
RCT, efficacy study
(VenaFlow Elite
NCT01317160
system)
A Multicenter Randomized Trial
Comparing Antiglide and Lateral
Plate Fixation in Ankle Fractures
NCT00718302
Lateral Ankle Sprain Study
RCT
NCT00761865
A Double Blind Randomized Study
on Adjunctive Use of Pulsed
Electromagnetic Fields in the
Treatment of 5th Metatarsal NonUnion Fracture
RCT, efficacy study
NCT00586170
Comparison of Biodegradable &
Metal Plates for Fixing Ankle
Fracture
Safety/efficacy study
NCT00864877
Bi-trimalleolar Fracture and APOS
System Treatment
Phase I: RCT
NCT01127776
Tape versus brace treatment of
ankle distortion
RCT, efficacy study
ISRCTN58932628
Achilles Tendon
Rupture
Rec
10
Adt Nov-10 Jul-13 Orthopedic Foot http://ClinicalTrials.gov/show/NCT01237613
Sen
and Ankle
Center, Ohio;
Artimplant AB
Rupture; Venous
Thromboembolism;
Venous Thrombosis;
Surgical Wound
Infection
Rec
100
Active,
NR
249
Adt Mar-11 Jun-13 Karolinska
Sen
University
Hospital;
Stockholm
County Council,
Sweden; DJO
Incorporated
Adt Jun-08 Dec-12 Boston Medical http://ClinicalTrials.gov/show/NCT00718302
Sen
Center
Rec
100
Term
9
Device: Antiglide
Ankle Injuries
Plate; Device: Lateral
Plate
Device: Air Cast
Later Ankle Sprain
Stirrup Brace & High
Tide Fracture Boot
Device: EBI Bone
5th Metatarsal Non
Healing System
Union Fracture
Adt Oct-08 Aug-12 University of
Sen
Rochester
Adt Nov-07 Aug-12 EBI, LLC dba
Sen
Biomet Spine,
Biomet Trauma,
Biomet
Osteobiologics
and Biomet
Bracing
Adt May-09 Apr-12
Inion Oy
Device:
Distal Fibular
Not yet
biodegradable
Fracture; Bimalleolar Rec
fixation system (Inion Fracture;
OTPS
Trimalleolar Fracture
FreedomPlateTM)
Device: APOS
Bi-trimalleolar
Rec
60 Adult Oct-10 Mar-12 Meir Medical
SYSTEM; Other:
Fracture of Ankle
Center
APOS SYSTEM
without
biomechanics units.
Tape treatment;
Ankle distortion,
Comp 100 Child Jan-08 Dec-11 Maastricht
semi-rigid brace
ankle ligament
Adt
University
(AirLoc® Bauerfeind, rupture
Medical Center
Germany)
(Netherlands)
304
Tape Versus Semirigid Versus
Lace-up Ankle Support in the
Treatment of Acute Lateral Ankle
Ligament Injury.
study
NCT01126242
Outcomes of Operative Treatment
of Unstable Ankle Fracture Comparison Between Metallic and
Biodegradable Implants
NCT01431560
A Comparison of Steel and
Bioabsorbable Screw Fixation of
Lisfranc Foot Injuries
Phase IV: RCT
NCT00689962
Acute Achilles Repair With or
Without OrthADAPT Augmentation
RCT, efficacy study
NCT00962143
Device: Tape;
Grade II and III
Device: Semi rigid
Acute Lateral Ankle
brace; Device: Lace- Ligament Injuries
up brace
Device: fixation of
Ankle Fracture
the ankle fracture
(Solco ); Device:
fixation of the ankle
fracture (Freedom)
Comp
Device: Linvatec 4.5 Joint Instability
mm Smart Screw;
Device: Synthes 4.0
mm steel screw
Device: Achilles
repair with
OrthADAPT
augmentation;
Procedure: Achilles
repair without
OrthADAPT
Augmentation
Achilles Tendon
Tear
Dietary supplement
The Effect of Vitamin c on
Dietary Supplement: Ankle Fracture
Preventing Complex Regional Pain vitamin c; Drug:
Syndrome (CRPS Type I)
placebo
Following Ankle Fracture
RCT, efficacy study
NCT01338129
The Use of Teriparatide as an
Adjunctive Therapy for the
Treatment of Jones Fractures
NCT01173081
Rec
Drug: Teriparatide;
Drug: Placebo
Fractures
182
Adt May-10 Nov-11 Gelre Hospitals http://ClinicalTrials.gov/show/NCT01126242
Sen
109 Child Jun-08 Aug-11 National Police
Adt
Hospital
Sen
Rec
60
Adt
Sen
Term
55
Adt Jun-08 Jan-11 Synovis Surgical http://ClinicalTrials.gov/show/NCT00962143
Sen
Innovations
Not yet 100
Rec
Rec
38
305
Jul-08
Jul-11 Rothman
Institute
Orthopaedics
Adt Apr-11 Feb-14 Rabin Medical
Sen
Center
Adt
Sen
Jul-10 Apr-14 Ohio Orthopedic http://ClinicalTrials.gov/show/NCT01173081
Center of
Excellence; Eli
Lilly and
Company
Low-Molecular-Weight Heparin
(LMWH) for Deep Venous
Thrombosis (DVT) Prophylaxis
study
NCT01029821
Lymphomyosot for Ankle Edema
Following Fracture
study
NCT00884988
Platelet rich plasma in Accelerated
Tendo-achilles Healing
RCT, efficacy study
ISRCTN93608625
Drug: LowMolecular-Weight
Heparin
Deep Venous
Thrombosis; Ankle
fractures
Rec
100
Adt Feb-10 Dec-13 University of
Sen
Tennessee
Drug:
Lymphomyosot;
Drug: Placebo
remedy
Ankle Injuries;
Fracture
Susp
60
Adt Feb-10 Dec-12 Shaare Zedek
Sen
Medical Center
Standard cast
immobilisation group
± Platelet rich
plasma; Standard
surgical repair ±
Platelet rich plasma
Drug: Nadroparin;
Drug: Fondaparinux
Acute achilles
tendon rupture
Active
360
Oxford (UK)
Rec
669
Adt Apr-09 Apr-11 Red Cross
Sen
Hospital
Beverwijk
Rec
669
Adt Apr-09 Apr-11 Red Cross
Sen
Hospital
Beverwijk
Prophylaxis of Thromboembolic
Deep Vein
Complications Trial:
Thrombosis;
Thromboprophylaxis Needed in
Pulmonary
Below Knee Plaster Cast
Embolism
Immobilization for Ankle and Foot
Fractures
study
NCT00881088
Prophylaxis of Thromboembolic
Drug: Nadroparin;
Deep Vein
Complications Trial:
Drug: Fondaparinux Thrombosis;
Thromboprophylaxis Needed in
Pulmonary
Below Knee Plaster Cast
Embolism
Immobilization for Ankle and Foot
Fractures
study
NCT00881088
306
Procedure
Combined Randomised and
Observational Study of Type B
Ankle Fracture Treatment
NCT01134094
Procedure: Open
Ankle Fractures
reduction internal
fixation of the ankle;
Procedure: Non
Operative
Arthrodesis Versus Extra-articular Procedure:
Lisfranc Injuries
Platefixation in Lisfranc Injury
Temporary
RCT, efficacy study
extraarticular plate
NCT01448941
fixation
Comparison of close contact cast Close contact casting Displaced unstable
(CCC) technique to open surgical technique; Open
fracture of the ankle
reduction and internal fixation
surgical reduction +
(ORIF) in the treatment of unstable internal fixation
ankle fractures in patients over 60
years
RCT
ISRCTN04180738
Hyperbaric Oxygen Therapy in
Procedure: HBOT; Microcirculation;
Calcaneal Intraarticular Fractures: Procedure: Placebo Wound Healing
Can it Decrease the Soft-tissue
(Sham)
Complication Rate?
NCT01264146
Non-operative Treatment of Acute Procedure: Early
Acute Achilles
Achilles Tendon Rupture Using
weight-bearing
Tendon Rupture
Dynamic Rehabilitation. Influence
of Early Weight-bearing Compared
With Non-weight-bearing
RCT, efficacy study
NCT01470833
Aspiration for Pain Relief Following Procedure: Ankle
Ankle Fracture
Ankle Fracture
Aspiration;
Procedure: Ankle
NCT01484535
aspiration Standard
Anterolateral
Rec
160
Rec
50
Active
620
Sen
Oxford (UK)
Rec
160
Adt Jan-11 Jul-14 RWTH Aachen
Sen
University
Rec
60
Adt
Invite
120
Adt Sep-11 Dec-13 Mayo Clinic
Sen
307
Adt Aug-10 Dec-16 The University of http://ClinicalTrials.gov/show/NCT01134094
New South
Wales; Whitlam
Orthopaedic
Research
Centre;
CROSSBAT
Investigators
Adt Oct-11 Dec-15 Oslo University http://ClinicalTrials.gov/show/NCT01448941
Hospital
Apr-11 Apr-14 Hvidovre
University
Hospital; DJO
Incorporated
Comparative Study of Fixation or
Fusion of Calcaneal Fractures
RCT
NCT00679393
Procedure: Open
reduction internal
fixation; Procedure:
Fusion
Fractures,
Comminuted;
Fracture Fixation,
Internal
Closed Reduction versus Open
reduction and internal fixation
versus Non-Operative Study of
intra-articular calcaneal fractures
RCT
ISRCTN67665340
Vacuum Assisted Closure as a
Treatment for Soft Tissue Injuries
RCT, efficacy study
NCT00582998
Treatment for Soft Tissue Injuries
RCT, efficacy study
NCT00582998
After Surgical Treatment of
Rupture of the Achilles Tendon
NCT01265004
A Comparison of Stainless Steel
and Bioabsorbable Screw Fixation
of Lisfranc Foot Injuries
Phase IV: RCT
NCT00985023
Closed reduction;
open reduction +
internal fixation;
conservation
treatment
Intraarticular
calcaneal fractures
Active
Procedure: Standard Fracture of
Wound Dressing;
Calcaneus, Pilon or
Device: VAC
Tibial Plateau
Active,
NR
189
Procedure: Standard Fracture of
Wound Dressing;
Calcaneus, Pilon or
Device: VAC
Tibial Plateau
Active,
NR
189
Microcirculation;
Achilles Tendon
Rupture
Rec
90
Unstable Lisfranc
Fracture-dislocations
of the Midfoot
Rec
60
Adt Aug-08 Aug-12 Rothman
Sen
Institute
Orthopaedics
Comp
20
Sen
Warwick (UK)
Procedure: Stitches;
Procedure: Fibringlue; Procedure:
Stitches and Fibringlue
Procedure: Steel
screw fixation of
Lisfranc fracturedislocation.;
Procedure:
Absorbable screw
fixation of Lisfranc
fracture-dislocations.
Achilles Tendinopathy
Plasma-rich plasma;
Management: platelet-rich plasma Eccentric loading
versus eccentric loading
programme.
programme
RCT
Achilles
tendinopathy
Rec
66
Child Feb-04 Dec-13 University of
Adt
Calgary;
Orthopaedic
Trauma
Association; AO
North America
150 Adt Jul-06 Jul-13 Erasmus
Medical Center, trials.com/ISRCTN67665340
Department of
Surgery (The
Netherlands)
ISRCTN95369715
308
Sen
Alabama at
Birmingham; KCI
USA, Inc.
Sen
Alabama at
Birmingham; KCI
USA, Inc.
Adt Dec-10 Dec-12 RWTH Aachen http://ClinicalTrials.gov/show/NCT01265004
Sen
University
Static Implant Versus Dynamic
Implant in the Surgical Treatment
on Ankle Syndesmosis Rupture
RCT, efficacy study
NCT01109303
Procedure:
TightRope SystemArthrex® / Dynamic
Implant; Procedure:
Screw fixation Synthes® / Static
Implant
UK heel fracture trial: surgical
Open reduction +
treatment versus non-operative
internal fixation;
care
conservation with
RCT
elevation + ice +
ISRCTN37188541
spintage + early
mobilisation
Syndesmotic Injury and Fixation in Procedure: fixation
Supination-External (SE) Ankle
Fractures
NCT01234493
Operative Versus Non Operative Procedure: non
Treatment for Unstable Ankle
operative treatment;
Fractures
Procedure: operative
RCT
vs non operative
NCT00336752
treatment
Open Reduction Internal Fixation Procedure: ORIF of
of Calcaneus Fractures With and Calcaneus with bone
Without Bone Graft
grafting; Procedure:
RCT, efficacy study
ORIF of Calcaneus
NCT00582686
without bone grafting
AS04 Ankle study of fracture
Surgical open
treatment in the older patient
reduction & internal
RCT
fixation (metal plates
ISRCTN81174170
and screws); closed
manipulation of the
fracture & close
contact cast.
Trauma Expectation Factor
Procedure: ankle or
Trauma Outcome Measure
distal tibia surgery
NCT01126398
Ankle Syndesmosis
Rupture
Active,
NR
70
Closed displaced
intra-articular
fractures of the
calcaneus
Comop 150
Trauma
Comp
140 Child Jun-07 Aug-10 University of
Adt
Oulu
Sen
Ankle Injuries
Comp
80
Adt
Calcaneus Fractures Active,
NR
49
Adt May-00 Aug-10 University of
Sen
Alabama at
Birmingham
Unstable ankle
fracture
Comp
120
Adt May-04 Jul-10 Oxford Radcliffe http://www.controlledSen
Hospitals NHS trials.com/ISRCTN81174170
Trust (UK)
Ankle Fracture; Pilon Comp
Fracture
204
Adt Feb-07 Feb-10 AO Clinical
Sen
Investigation and
Documentation
309
Adt
Oct-08 Jan-12 Hopital de
l'Enfant-Jesus;
Arthrex, Inc.
Adt Jun-06 Nov-10 University
Hospitals
Coventry and
Warwickshire
NHS Trust (UK)
Jun-03 Aug-10 Lawson Health
Research
Institute
Rest Easy: Is Bed Rest Really
Necessary After Surgical Repair of
an Ankle Fracture?
NCT00690651
Other
Alcohol Intervention in an Acute
Surgical Setting
RCT, efficacy study
NCT00986791
Ankle Fracture Treatment in the
Elderly
NCT01444144
Ankle Sprain Rehabilitation With
the Wii Balance Board
NCT01449760
Ankle Manual Therapy for Ankle
Sprains
study
NCT00888498
Procedure: Early
Ankle Injuries;
mobilization;
Fracture
Procedure: Standard
mobilization
Comp
104
Adt
Sen
Other: Postoperative Acute Surgery;
alcohol cessation
Alcohol Intervention;
intervention
Postoperative
programme; Other: Morbidity; Infection;
Standard treatment Ankle Injuries
Other: Fracture union Ankle Fracture
Rec
160
Adt Nov-09 Dec-15 Bispebjerg
Sen
Hospital,
Denmark
Rec
150
Sen
Florida
Other: Physical
Ankle Sprain
Therapy; Other: Wii
Balance Board
Rec
300
Hospital,
Geneva
Other: Passive
Sprains and Strains
Positioning; Other:
High-Velocity, LowAmplitude Stretch;
Other: Slow,
Mobilization Stretch
Rec
189 Child Jan-09 Dec-12 University of the http://ClinicalTrials.gov/show/NCT00888498
Adt
Pacific;
University of
Southern
California;
American
Physical
Therapy
Association
50 Child Jun-10 Dec-11 Rhode Island
Adt
Hospital
Bedside Ultrasound in the
Other: Ultrasound
Ankle Fracture
Diagnosis of Ankle Fractures in
Children
efficacy study
NCT01341015
A Comparison of Early Mobilization Other: Jump Stretch Acute; Ankle; Sprain
Versus Traditional Treatment for
Acute Ankle Sprains.
RCT
NCT01134653
Rec
Rec
60
310
Jul-08 Jan-10 The Alfred;
National Trauma
Research
Institute
Child Jan-10 Jun-11 Nationwide
Adt
Children's
Hospital
Comparative Results of
Conservatively and Surgically
Treated Adolescents With Triplane
and Juvenile Tillaux Ankle
Fractures After Skeletal Maturity
NCT00541580
Intraoperative Three Dimensional
Fluoroscopy Compared to
Standard Fluoroscopy for the
Assessment of Reduction of Ankle
Fractures With Syndesmosis
Disruption
NCT00556010
Adt
Sep-11 Hadassah
Medical
Organization
Adt
Jan-09 Jul-11 Hadassah
Medical
Organization
Ankle Injuries
Term
Ankle Injuries
Active,
NR
40
Conditions
Recruit
n
Ankle Arthritis
Rec
200
Adt Jun-02 Jan-10 St. Michael's
Sen
Hospital,
Toronto;
Johnson &
Johnson
Primary Arthrosis;
Post Traumatic
Arthritis; Rheumatoid
Arthritis;
Osteoarthritis
Rec
98
Adt Nov-10 Jun-14 Small Bone
Sen
Innovations, Inc.
A10C: ARTHROPLASTY
Title
Interventions
CT ID
Behavioural
Gait Analysis of Ankle Arthroplasty Behavioral: Gait
and Arthrodesis
Analysis
assignment
NCT00921076
Device
2-Year Post-Approval Study to
Investigate the Scandinavian Total
Ankle Replacement System
(STAR) Ankle Under Actual
Conditions of Use
efficacy study
NCT01284283
Device:
Scandinavian Total
Ankle Replacement
System (STAR
Ankle)
311
Age Start
(Grp) Date
End Sponsors
Date
URL
Post-Approval Study to Investigate
the Long Term (8 Year)
Survivorship of STAR Ankle
Among Continued Access Study
Patients
NCT01288586
A Study to Evaluate the
Effectiveness and Safety of an
Implant in the Treatment of
Osteoarthritis of the Great Toe
Phase III: RCT
NCT00969969
A randomised trial of ankle joint
replacements
RCT
ISRCTN66721986
Evaluation of Trinity Evolution in
Patients Undergoing Foot and
Ankle Fusion
NCT00988338
ACP for Local Application in Ankle
Arthrodesis
assignment
NCT01131455
Device:
Primary Arthrosis
Scandinavian Total
Ankle Replacement
System (STAR
Ankle)
Rec
125
Adt Jan-11 May-14 Small Bone
Sen
Innovations, Inc.
Device: Arthrodesis; First MTP Joint
Device: Cartiva
Osteoarthritis
Rec
230
Adt Aug-09 Aug-11 Carticept
Sen
Medical, Inc
Comp
N/K
N/K Jan-00 Jan-10 Department of
Health (UK)
Tibiotalar
Active,
Arthrodesis; Subtalar NR
Arthrodesis;
Calcaneocuboid
Arthrodesis;
Talonavicular
Arthrodesis; Double
Arthrodesis (i.e.
Calcaneocuboid and
Talonavicular); Triple
Arthrodesis (i.e.
Subtalar,
Calcaneocuboid,
and Talonavicular)
Ankle Arthritis
Term
100
Adt Sep-09 Aug-12 Orthofix Inc.
Sen
10
Adt Oct-09 Jul-10 Columbia
Sen
Orthopaedic
Group, LLP
Scandinavian Total Total Ankle
Ankle Replacement replacement
(STAR); BuechelPappas (BP) total
ankle replacements
Biological: Trinity
Evolution
Biological:
Autologous
Concentrated
Plasma
312
Procedure
Canadian Orthopaedic Foot and
Ankle Society Surgical Treatment
of Ankle Arthritis Outcome Study
Phase IV: RCT
NCT00552136
Procedure: Ankle
Arthroplasty;
Procedure: Ankle
Arthrodesis
Total Ankle Replacement Versus
Ankle Arthrodesis Trial
RCT, efficacy study
NCT01518361
Procedure: Total
End-stage Ankle
Ankle Replacement; Osteoarthritis
Procedure: Ankle
Arthrodesis
Ankle Arthritis
Rec
Not yet 188
Rec
Study of Subtalar Arthrodesis
Using AlloStem® Versus
Autologous Bone Graft
NCT01413061
Procedure: Subtalar Degenerative
Active,
Arthrodesis
traumatic; Arthrosis;
and Other
Inflammatory
Polyarthropathies;
of Subtalar Joint
Efficacy of a physical therapy
Usual care +
Ankle sprain
Comp
intervention for the early treatment standardised
of acute ankle sprains identified in physical therapy
the emergency department: a
intervention; Usual
randomised controlled trial
care
RCT
ISRCTN74033088
INBONE Total Ankle
Arthroplasty(TAA)Using Calcaneal
Stem Fixation
NCT01366989
Arthrodesis;
Degenerative
Arthritis; Rheumatoid
Arthritis;
Complications;
Arthroplasty,
Mechanical
Rec
136
Adt Feb-05 Apr-20 Capital District http://ClinicalTrials.gov/show/NCT00552136
Sen
Health Authority,
Canada;
Canadian
Orthopaedic
Foot and Ankle
Society;
Johnson &
Johnson
Adt May-12 Jul-15 Razi Zaidi;
Sen
University
College, London;
Medical
Research
Council
Adt Jun-10 Dec-14 AlloSource
Sen
512 Child Sep-09 Aug-11 Queen’s
Adt
University
Sen
(Canada)
95
313
Adt Oct-10 Dec-13 Wright Medical http://ClinicalTrials.gov/show/NCT01366989
Sen
Technology;
Duke University
Short Term Follow-up of Patient
Implanted With the MetatarsoPhalangeal Prosthesis METIS®
NCT01284985
Short Term Follow-up of Patient
Implanted With the Proximal
Interphalangeal Implant
NCT01285011
Follow-up of Patient Implanted
With the Staple ASTUS®
NCT01518543
Agility LP Ankle Arthroplasty
Outcomes
NCT01366872
Arthroscopic Ankle Arthrodesis:
Measuring Post-operative Pain to
Assess the Potential for Outpatient
Surgery.
NCT01370252
Clinical Experience With the
Hindfoot Arthrodesis Nail for the
Surgical Treatment of Ankle and
Hindfoot Pathologies
NCT00942032
HINTEGRA Total Ankle Prosthesis
Follow-up
Case-only study
NCT01284972
Hallux Rigidus;
Active,
Hallux Limitus;
NR
Hallux Valgus;
Osteoarthritis;
- Ankle and/or Foot
Hammer Toe; Claw Active,
Toe; Shortening 2nd
NR
Toe; Revision of
Arthrodesis or
Arthroplasty Failure
Arthrodesis
Term
115
Adt Feb-09 Jun-13 Integra
Sen
LifeSciences
Services
153
Adt Apr-09 Jul-12 Integra
Sen
LifeSciences
Services
5
Adt Apr-10 Mar-12 Integra
Sen
LifeSciences
Services
of Ankle;
Osteoarthritis of
Ankle; Traumatic
Arthritis of Ankle
Osteoarthritis
Rec
50
Adt Dec-10 Dec-11 Orthopaedic
Sen
Associates of
Michigan, PC
Rec
40
Child Jun-11 Jun-11 Hammond,
Adt
Allan, M.D.
Sen
Hindfoot Arthrodesis; Comp
Hindfoot Pathologies
39
Child May-09 Apr-11 AO Clinical
Adt
Investigation and
Sen
Documentation;
Synthes Inc.
Total Ankle
Prosthesis
225
Adt Feb-09 Dec-10 Integra
Sen
LifeSciences
Services
Comp
314
A10D: OTHER
Title
CT ID
Device
Augment™ Injectable Bone Graft
Compared to Autologous Bone
Graft as a Bone Regeneration
Device in Hindfoot Fusions
study
NCT01305356
Comparison Between Implanted
Functional Electrical Stimulation
and Foot Orthosis
RCT
NCT01415700
Measures of Gait Efficiency of
Three Multi-Axial, Vertical Shock
and Energy Storing-Return
Prosthetic Feet During Simple &
Complex Mobility Activities
NCT01404559
Evaluation of a Pro-Active
Dynamic Accommodating Socket
study
NCT01546311
Interventions
Ankle Joint Replacement
Outcomes Study
NCT00503438
Device: ankle joint
replacement
Conditions
Recruit
n
Device: Augment(tm) Degenerative Joint
Injectable Bone
Disease; Congenital
Graft; Procedure:
Deformity; Arthritis;
Autologous bone
Osteoarthritis;
graft
Rec
201
Adt Mar-11 Mar-14 BioMimetic
Sen
Therapeutics
Device: Functional Hysterical Simulation
electrical stimulator; of Disease
Device: feet orthosis
Rec
50
Adt Oct-10 Jan-14 Assistance
Sen
Paris
Not yet
Rec
28
Adt
Rec
5
Rec
200
Adt Jan-12 Dec-12 Infoscitex
Sen
Corporation;
Liberating
Technologies,
Inc;
Telemedicine
and Advanced
Technology
Research Center
(TATRC)
Adt Jul-07 Jun-12 Tornier
Sen
Device: Ossur
Amputation
Ceterus prosthetic
foot; Device: Ossur
Variflex prosthetic
foot; Device:
Freedom Innovations
Silhouette VS
Device: Pro Active Amputation
Dynamic
Accommodating
Socket
Osteoarthritis;
Post-Traumatic
Arthritis; Septic
Arthritis; Prior Ankle
Fusion
315
Age Start
(Grp) Date
End Sponsors
Date
Oct-11 Sep-13 University of
South Florida
URL
A Study Evaluating Amplex
Compared To Autograft Bone In
Foot and Ankle Fusion Surgery
study
NCT01224119
Heel Cushion for Plantar Fasciitis
NCT01017406
Device: Amplex;
Arthritis
Procedure: Autograft
bone
Device: PSU heel
cushion and plantar
fascia specific
stretching exercise
Comparative Study of
Device: Fracture
Osteosynthesis for Chevron
compressing screw
Osteotomy of Hallux Valgus Using ZfW 102 Königsee
Degradable Versus NonImplantate GmbH;
degradable Metallic Device
Device: Fracture
RCT, efficacy study
compressing screw
NCT01535144
titanium Königsee
Implantate GmbH
Comparative Study of
Device: Fracture
Osteosynthesis for Chevron
compressing screw
Osteotomy of Hallux Valgus Using ZfW 102 Königsee
Degradable Versus NonImplantate GmbH;
degradable Metallic Device
Device: Fracture
RCT, efficacy study
compressing screw
NCT01535144
titanium Königsee
Implantate GmbH
PISCES: Pressure and pain In
Pressure relieving
SCleroderma an Evaluation of a
insole; Placebo
Simple intervention
insole
RCT
ISRCTN02824122
Artelon Metatarsophalangeal
Device: Artelon MTP
(MTP) Spacer
Spacer
assignment
NCT01028469
Augment™ Injectable Bone Graft Device: Augment™
Injectable;
Graft in Foot and Ankle Fusions
Procedure: Standard
of care
NCT01008891
Active,
NR
24
Adt Jan-11 Apr-12 BioSurface
Sen
Engineering
Technologies,
Inc
Plantar Fasciitis
Invite
160 Child Jan-10 Apr-12 Prince of
Adt
Songkla
University
Hallux Valgus
Comp
26
Adt Feb-10 Feb-12 Syntellix AG
Sen
Hallux Valgus
Comp
26
Adt Feb-10 Feb-12 Syntellix AG
Sen
Scleroderma
Comp
140
Adt
Sen
Rec
15
Child Dec-09 Dec-11 Artimplant AB
Adt
Sen
Active,
NR
180
Adt Sep-09 Sep-11 BioMimetic
Sen
Therapeutics
Osteoarthritis; Hallux
Rigidus
Ankle/Hindfoot
Fusion
316
Leeds (UK)
Wdrwn
90
Adt
Jun-07 Jul-11 ArthroCare
Corporation
Term
60
Amputation
Active,
NR
20
Orthopedic Surgery
Not yet
Rec
75
Functional foot
Foot pain; Healthy
orthoses; Inert
cushioning orthoses
Comp
120
Adt Mar-09 Jun-11 OrthoCarolina
Sen
Research
Institute, Inc.;
Wright Medical
Technology
Adt Mar-09 Jun-11 Department of
Veterans Affairs;
Massachusetts
Institute of
Technology
Adt Feb-10 Apr-11 Nottingham
Sen
University
Hospitals NHS
Trust
Adt May-09 Jan-11 University of
Sen
Leeds (UK)
Device: Iceman®
Narcotic
Cold Therapy unit
Consumption; Pain;
(djOrtho); Other: Ice Wound Healing;
Patient Satisfaction
Term
82
Child Feb-07 Dec-10 OrthoCarolina
Adt
Research
Sen
Institute, Inc.;
DJO
Incorporated
Device: V.A.C. by
K.C.I.
Comp
106
Sen
University
Comp
69
Adt Oct-09 Sep-10 Henry DeGroot, http://ClinicalTrials.gov/show/NCT01243814
Sen
M.D.
Clinical Evaluation of Placement of Device: TOPAZ
Radiofrequency-based Plasma
MicroDebrider
Microdebridement in the Treatment
Algorithm for Foot and Ankle
Tendinosis and Plantar Fasciosis
NCT00420875
Comparison Study of Biofoam
Device: Biofoam;
Porous Metal Versus Allograft to Other: Iliac Crest
Treat Adult Acquired Flatfoot
Allograft with locked
plate
NCT00949897
Effects of Wearing a Powered
Device: Powered
Ankle-Foot Prosthesis on Amputee ankle-foot prosthesis
Walking
Efficacy study
NCT00869947
Pain Relief After Forefoot Surgery Device: Catheter
NCT01019005
Causes and treatments in
mechanically induced foot pain
RCT
ISRCTN77862746
Motorized Continuous Cold
Therapy Versus Standard Post-op
Icing Protocol for Two Foot and
Ankle Procedures
NCT00950183
Dressing Study
RCT, efficacy study
NCT01366105
A Double-blind RCT of a Single
Dose of Hyaluronan in the
Treatment of Osteoarthritis of the
Ankle
RCT, efficacy study
NCT01243814
Plantar Fasciosis,
Achilles Tendinosis
Adult Acquired
Flatfoot
Surgical Wound
Infection
Device: hyaluronate Osteoarthritis
intra-articular
injection; Device:
placebo injection
317
Achilles Tendinosis Study;
Comparison of Radiofrequency to
Surgical MicroDebridement
NCT00534781
Stability and 3D Motion Study of
an Experimental Prosthetic Foot
Phase III: RCT
NCT00968292
Assessment of the Ability of Ionic
Foot Bath (IonCleanse®) to
Remove Heavy Metals Through
the Feet and Its Potential Impact
on Body Burden of Heavy Metals
efficacy study
NCT01125592
Clinical Trial of Tensegrity
Prosthetics K3 Promoter Foot
Prosthesis
NCT00888199
Evaluation of the Efficiency of the
Echelon Foot in Traumatic Trans
Tibial Amputees
assignment
NCT01004926
GEM OS™1 Bone Graft
Graft in Foot and Ankle Fusions
NCT00583375
Ketorolac Effects on Postoperative Pain and Bone Healing
RCT, efficacy study
NCT01133639
Device: plasma
Achilles Pain;
Wdrwn
microdebrider;
Achilles Tendinosis;
Procedure:
Heel Pain
Mechanical Surgical
Debridement
Device: Experimental Amputation
Not yet
prosthetics foot (K3
Rec
Promoter)
60
Adt Sep-07 Sep-10 ArthroCare
Sen
Corporation
50
Adt May-10 Aug-10 Tensegrity
Sen
Prosthetics
Device: IonCLeanse Healthy
Footbath
Comp
6
Child May-10 Jul-10 The Canadian
Adt
College of
Sen
Naturopathic
Medicine
Device: Experimental Amputation
prosthetic foot (K3
Promoter)
Not yet
Rec
80
Device: Echelon foot Unilateral Trans
Tibial Amputation
Not yet
Rec
10
Adt Jan-10 Jun-10 Tensegrity
Sen
Prosthetics;
National
Institutes of
Health
Adt Oct-09 Mar-10 Sheba Medical
Sen
Center
Device: GEM OS1; Foot Fusion
Procedure: Standard
of Care
Comp
396
Adt Apr-07 Feb-10 BioMimetic
Sen
Therapeutics
Rec
88
Adt May-10 May-13 Beth Israel
Deaconess
Medical Center;
American
College of Foot
and Ankle
Surgeons
Drug: Ketorolac;
Drug: Placebo
Bunion
318
Regional Anesthesia for Major
Drug:
Nerve Block
Surgery of the Foot.
levobupivacaïne 0,5
Levobupivacaïne Ropivacaine
%; Drug: ropivacaïne
0.5% Versus 0.5% in the Sciatic
0,5 %
Block Through médiofémorale
NCT00956709
Side Effects of Autologous
Biological:
Osteoarthritis
Mesenchymal Stem Cell
mesenchymal stem
Transplantation in Ankle Joint
cell
Osteoartritis
NCT01436058
Treatment of Plantar Fasciitis With Biological: platelet
Plantar Fasciitis
Platelet Rich Plasma
rich plasma; Drug:
RCT, efficacy study
corticosteroid
NCT01127672
injection
Device: Focused
Epicondylitis;
Tendinopathies
Topical NO;
study
Behavioral: Painful
NCT01185951
Achilles
tendinopathy;
Behavioral: Painful
on 25Â° decline
board; Behavioral:
Painful eccentric
training for elbow
tendinopathy using
Thera-Band Flex-Bar
A Study Comparing Etoricoxib and Drug: etoricoxib;
Hallux Valgus;
Diclofenac Sodium in Post Hallux Drug: Diclofenac
Postoperative Pain
Valgus Surgery Pain
study
NCT01190722
Rec
42
Adt Dec-08 Oct-11 Nantes
University
Hospital
Comp
6
Adt Sep-10 Sep-11 Royan Institute
Not yet
Rec
50
Adt May-10 May-11 Loma Linda
Sen
University
Active,
NR
114
Sen
Medical School
Adt Nov-10 Jul-10 Karolinska
Institutet
Wdrwn 200
319
Procedure
Treatment Outcomes for Ankle
Arthritis
NCT00391365
Procedure: Gait
analysis
Osteoarthritis
Ultrasound Guided Ankle Block
Procedure:
Pain Relief After
Versus Medial Forefoot Block for Ultrasound guided
Forefoot Surgery
Forefoot Surgery
ankle block;
RCT, efficacy study
Procedure: Medial
NCT01386320
forefoot block
A Randomized Trial to Evaluate
Procedure: Flexor
Achilles
the Effectiveness of Transferring Hallucis Longus
Tendinopathy
the Flexor Hallucis Longus Tendon Tendon transfer;
Phase IV: RCT, safety/efficacy Procedure: Transfer
study
of the Flexor Hallucis
NCT01341509
Longus Tendon;
Procedure: No
transfer of Flexor
Hallucis Longus
tendon
Placement of Perineural Catheters Procedure:
Foot Surgery
in the Popliteal Region
Placement of
Phase IV: RCT, safety/efficacy perineural catheters
study
with
NCT01546077
Hydrolocalization
technique using
Rec
500
Rec
60
Rec
20
Adt Apr-11 Apr-14 OAD
Sen
Orthopaedics
Rec
40
Adt Jan-12 Mar-13 Attikon Hospital http://ClinicalTrials.gov/show/NCT01546077
Sen
320
Adt Oct-06 Sep-15 Department of http://ClinicalTrials.gov/show/NCT00391365
Sen
Veterans Affairs;
Orthopaedic
Associates of
Michigan, PC;
Orthopedic &
Fracture Clinic;
Minnesota
Orthopedic
Sports Medicine
Institute Twin
Cities
Orthopedics
Adt Feb-11 Oct-14 Hull and East
Sen
Yorkshire
Hospitals NHS
Trust
Continuous Popliteal Nerve
Blocks: Effect of Perineural
Catheter Tip Location Relative to
the Sciatic Nerve Bifurcation on
Postoperative Analgesia
study
NCT01229696
Ankle Block Versus Popliteal
Fossa Block as Primary
Anesthesia for Forefoot Surgical
Procedures
NCT01376960
Blocks
study
NCT00771862
Popliteal Sciatic Nerve Block
Catheter Placement for Foot
Surgery
RCT
NCT01049906
Ultrasound-Guided Continuous
Sciatic Nerve Blocks: Popliteal
Versus Subgluteal Catheters
Phase IV: RCT,
NCT01325012
Saphenous Nerve Block: Single
Shot Versus Continuous Infusion
to Supplement a Continuous
Sciatic Nerve Block After Major
Ankle Surgery
RCT, efficacy study
NCT01445210
Procedure: Catheter
Placed At
Bifurcation;
Procedure: Catheter
Placed 5cm Above
Bifurcation
Popliteal Nerve
Block; Foot Surgery;
Ankle Surgery;
Popliteal Bifurcation
Rec
150
Sen
California, San
Diego
Procedure: elective
forefoot surgery
Anesthesia; Forefoot
Surgery
Rec
101 Child Jun-11 Dec-12 OrthoCarolina
Adt
Research
Sen
Institute, Inc.
Procedure:
Amputation;
Active,
NR
Stump Pain
18
Procedure:
Foot Surgery; Ankle
Placement of nerve Surgery
block catheter;
Procedure:
Placement of nerve
block catheter
Procedure:
Foot Surgery
Subgluteal Sciatic
Nerve Block;
Procedure: Popliteal
Sciatic Nerve Block
Active,
NR
124
Rec
40
Sen
California, San
Diego
Rec
50
Adt Sep-11 Jul-12 University of
Sen
Aarhus; Aarhus
University
Hospital
Procedure:
Continuous
saphenous nerve
block; Procedure:
Placebo
Major Ankle Surgery
321
Sen
California, San
Diego; National
Institute of
General Medical
Sciences
(NIGMS)
Adt Oct-09 Dec-12 Mayo Clinic
Sen
Chronic Insertional Achilles
Procedure: Achilles
Tendonitis Treated With or Without decompression &
Flexor Hallucis Longus Tendon
debridement;
Transfer
Procedure: Achilles
decompression and
NCT00950053
debridement with
FHL transfer
perineural
ropivacaine
and Stump Pain
RCT, efficacy study
NCT00667264
Effectiveness of extracorporeal
shock wave therapy in patients
with proximal plantar fasciitis
RCT
ISRCTN49594569
Eccentric Exercise for Chronic
Mid-portion Achilles Tendinopathy
RCT, efficacy study
NCT01225497
Chronic Insertional
Achilles Tendonitis
Active,
NR
52
Adt Dec-08 Jun-12 OrthoCarolina
Sen
Research
Institute, Inc.
Amputation;
Phantom Limb;
Stump Pain
Comp
7
Radial extracorporeal Chronic plantar
shock wave therapy; fasciitis
No active treatment
Comp
68
Sen
California, San
Diego; Summit
Medical;
National Institute
of General
Medical
Sciences
Adt Sep-09 Sep-11 The Hong Kong http://www.controlledPolytechnic
University
(China)
Achilles Tendon;
Tendinopathy
Not yet
Rec
52
Adt Nov-10 Feb-11 Queen Margaret http://ClinicalTrials.gov/show/NCT01225497
Sen
University
Sciatic Nerve
Blockade for
Foot/Ankle Surgery
Comp
64
Adt May-09 Dec-10 University Health http://ClinicalTrials.gov/show/NCT00802581
Sen
Network,
Toronto
Hallux Valgus
Invite
40
Adt Sep-08 Dec-10 Frederiksberg
Sen
University
Hospital
Procedure: Standard
eccentric exercise;
Procedure: Eccentric
exerciseExperimental group
Circumferential Spread of
Procedure:
Anesthetic and Success in Sciatic Circumferential
Nerve Blockade
spread of local
RCT, efficacy study
anesthetic;
NCT00802581
Procedure: Noncircumferential
spread of local
anesthetic
Home Infusors for Analgesia After Procedure:
Foot Surgery
elastomeric pump
with reservoir of 500
NCT00600899
ml, infusion rate of 8
ml/h; Procedure:
elastomeric pump
with reservoir of 275
ml, infusion rate of 5
ml/h
322
The CARROT trial: CAllus
Reduction Reinforcing Orthotic
Therapy
RCT, efficacy study
ISRCTN05190231
Effectiveness of radial shock wave
treatment or tissue-specific plantar
fascia-stretching in patients with
chronic plantar heel pain
RCT
ISRCTN11644582
Other
DeNovo NT Ankle LDC Study
Cohort study
NCT01347892
Prospective Randomized
Evaluation of a Two and Three
Piece Total Ankle Replacement
Phase IV: RCT
NCT01504438
Study of the Effect of Weight
Bearing Status on Patient
Outcomes After Surgery for
Osteochondral Defects of the
Ankle
RCT
NCT01405664
Sensory-Targeted Ankle
Rehabilitation Strategies (STARS)
NCT01541657
Callus debridement + Rheumatoid arthritis
usual longterm
therapies; usual
longterm therapies
only
Plantar fasciaPlantar fasciopathy
specific stretching
(PFSS); Radial
shock wave therapy
(RSWT); PFSS +
RSWT
Comp
64
Child Oct-07 Oct-10 Leeds Teaching http://www.controlledAdt
Hospital NHS
Sen
Trust (UK)
Comp
250
Adt
Sen
Other: DeNovo NT Articular Cartilage
Natural Tissue Graft Lesions or Defects;
Osteochondral
Lesions;
Osteochondritis
Dissicans
Other: Total Ankle
Ankle Osteoarthritis
Replacement
Surgery
Rec
250
Adt Mar-11 Sep-18 Zimmer
Sen
Orthobiologics,
Inc.
Rec
50
Adt Oct-11 Feb-16 Duke University http://ClinicalTrials.gov/show/NCT01504438
Sen
Other: WeightOsteochondritis
Bearing as Tolerated Dissecans of Ankle
and Joints of Foot
Not yet
Rec
68
Child Sep-11 Sep-13 Capital District http://ClinicalTrials.gov/show/NCT01405664
Adt
Health Authority,
Canada
Rec
80
Adt Dec-11 Apr-13 University of
Kentucky;
University of
North Carolina,
Charlotte;
National Institute
of Arthritis and
Musculoskeletal
and Skin
Diseases
Other: Ankle Joint
Mobilization; Other:
Foot Massage;
Other: Calf
Stretching
Chronic Ankle
Instability
323
Jul-07 Jan-10 OrthoTrauma
Evaluation
Center
(Germany)
Surgical Treatment for Hallux
Rigidus
Non-randomized, efficacy study
NCT01048450
Radiation: Joint
Resection- Keller
Procedure;
Procedure: Joint
Fusion; Procedure:
Hemi-metallic Joint
Implant
Neuro-orthopaedic Surgery in the
Treatment of the Spastic
Equinovarus Foot
NCT01265238
Short Term Follow-up of Patent
Implanted With the B-BOP Lock
Plate
NCT01284998
Microcirculatory Mapping of the
Aging Hand and Foot
NCT01235312
Hallux Limitus;
Hallux Rigidus
Comp
158
Adt
Sen
Rec
50
Adt Dec-09 Dec-12 University
Sen
Hospital of MontGodinne
Hallux Valgus;
Active,
Hallux Varus;
NR
Vicious Callus on M1
80
Adt Jun-09 Jul-12 Integra
Sen
LifeSciences
Services
Cutaneous
Microcirculation in
Vascular Diseases
Comp
120
Adt Sep-10 May-11 Hannover
Sen
Medical School
Conditions
Recruit
n
Age Start
(Grp) Date
Femur Fracture
Active,
NR
33
Child Nov-07 Dec-13 Biomet, Inc.
Muscle Spasticity;
Spastic Foot
(Finding); Stroke
Jul-09 Jun-11 American
College of Foot
and Ankle
Surgeons
A11. LOWER LIMB
A11A: PAEDIATRICS
Title
Interventions
CT ID
Device
Pediatric Locking Nail for the
Device: Pediatric
Treatment of Femoral Fractures in Locking Nail
Children
NCT00725894
324
End Sponsors
Date
URL
Efficacy Study of Femoral Nerve
Block in Children With a Femur
Fracture
RCT
NCT01294098
Spinal anaesthesia in adolescent
population with 2-chloroprocaine
1% for lower limb procedures of
short duration: a prospective,
randomised, blind-observer, dosefinding study
ISRCTN57987506
Botulinum toxin: an adjunct in limb
reconstruction - Can it reduce pain
lengthening phase?
RCT
ISRCTN35609758
Drug: Marcaine
Femoral Fractures;
Pain, Postoperative
Invite
180 Child Feb-11 Feb-13 Washington
University
School of
Medicine
2-chloroprocaine
Short duration (less
hydrochloride at 1% than 40 minutes)
concentration: 0.206 lower limb surgery
mg/cm; 0.235
mg/cm; 0.265
mg/cm.
Active
96
Child Mar-11 Oct-12 Sintetica S.A.
(Switzerland)
Botulinum toxin
intramuscular
injections; Saline
injections
Limb reconstruction
surgery; femoral or
tibial deformity;
congenital talipes
equinovarus
Comp
36
Foundation Trust
(UK)
Femoral Fractures
Invite
145 Child Jun-09 Jun-13 Washington
University
School of
Medicine;
University of
MissouriColumbia;
Children's Mercy
Hospital-Kansas
City, MO
25 Child Aug-07 Jun-11 University of
British Columbia
Procedure
Pediatric Femur Research Project Procedure: femur
fracture repair
NCT00943332
The Effect of Femoral Nerve Block
on Opioid Requirements After
Surgery for a Femur Fracture in
Children
study
NCT00175591
Procedure:
Pain, Postoperative
Administration of a
femoral nerve block
(bupivacaine HCL)
Term
325
Distal Rectus Femoris Transfer as
a Part of Multilevel Surgery in
Children With Spastic Diplegia
RCT
NCT01381198
Simultaneous Lengthening of
Bilateral Femora and Tibiae in
Achondroplastic Patients
efficacy study
NCT01328418
Study of Tibial Shaft Fractures in
Children
RCT
NCT01238523
Procedure: Distal
rectus femoris
transfer
Cerebral Palsy
Comp
36
Child Jun-07 May-11 University of
Heidelberg
Procedure:
Lengthening over
nail
SHOX Gene With
Short Stature
Comp
22
Child Apr-02 Mar-11 Bilen, Fikri Erkal, http://ClinicalTrials.gov/show/NCT01328418
M.D.
Procedure: Long leg Tibial Shaft
Comp
cast in full extension; Fractures in Children
Procedure: Long leg
cast with 45 degrees
of flexion
81
Child May-07 May-10 University of
California, Los
Angeles; Los
Angeles
Orthopaedic
Hospital
Foundation Trust
(UK)
Botulinum toxin: an adjunct in limb Botulinum toxin
reconstruction - Can it reduce pain intramuscular
injections; Placebo
lengthening phase?
RCT
ISRCTN35609758
Titanium Elastic Nailing Versus Hip Procedure: titanium
Spica Cast in Treatment of
elastic nailing;
Femoral Fractures in Children
Device: Hip spica
Phase II: Non-randomized,
casting
efficacy study
NCT01190696
Evaluation of the Change in
Length of the Leg in Children After
Treatment of Femur Fractures.
Phase II: Prospective, cohort
study
NCT00355420
Femoral or tibial
deformity;
Congenital talipes
equinovarus.
Comp
36
Femoral Shaft
Fracture
Comp
46
Fractures
Active,
NR
Child Feb-09 Jan-10 Isfahan
University of
Medical
Sciences
N/K Child Oct-06 Sep-11 Hadassah
Medical
Organization
326
Title
CT ID
Device
Comparing IM Nails and Plate
Fixation in Proximal Tibial
Fractures
RCT, efficacy study
NCT00429585
Comparing IM Nails and Plate
Fixation in Distal Femur Fractures
RCT, efficacy study
NCT00429663
rhBMP-2 Versus Autograft in
Critical Size Tibial Defects
study
NCT00853489
Interventions
Conditions
Device: reamed,
interlocking
intramedullary nail;
Device: locking
periarticular plate
Tibial Fractures
TRial to Evaluate UltraSound in
the Treatment of Tibial Fractures
RCT, efficacy study
NCT00667849
Device: Exogen
Bone Healing
System
Device: reamed,
Femoral Fractures
interlocking
intramedullary nail;
Device: locking
periarticular plate
Device: recombinant Tibial Fractures
human bone
morphogenetic
protein 2 (rhBMP-2)
(INFUSE);
Procedure:
Autogenous iliac
crest bone graft
Tibial Fractures
Recruit
n
Rec
160
Rec
160 Child Feb-07 Dec-14 Boston Medical http://ClinicalTrials.gov/show/NCT00429663
Adt
Center
Sen
Not yet
Rec
50
Rec
500
327
Age Start
(Grp) Date
End Sponsors
Date
URL
Adt Feb-07 Dec-14 Boston Medical http://ClinicalTrials.gov/show/NCT00429585
Sen
Center
Adt Aug-11 Aug-14 St. Louis
University;
Department of
Defense,
Orthopaedic
Extremity
Trauma
Research
Program
(OETRP); Major
Extremity
Trauma
Research
Consortium
Adt Sep-08 Dec-12 Smith &
Sen
Nephew, Inc.;
Canadian
Institutes of
Health Research
The Efficacy and Cost
Device: Cryotherapy; Proximal Tibia
Effectiveness of Preoperative and Device: Room
Fracture
Postoperative Cryotherapy in
temperature cuff
Proximal Tibia Fractures
NCT01104831
Trial to Evaluate the Effectiveness
of Angular Stable Locking System
(ASLS) in Patients With Distal
Tibial Fractures
RCT, efficacy study
NCT00875992
TRIGEN SURESHOT™ Distal
Targeting System Study
study
NCT01327508
Device: ETN with
Tibial Fractures
ASLS; Device: ETN
locked with
conventional locking
bolts
Device: TRIGEN
Femoral Shaft
SURESHOT Distal Fracture
Targeting
Instrumentation.;
Other: Free hand
Technique
Lateral Versus Anterior Spanning Device: Anterior pin Fractures, Closed
External Fixator for Tibial Plateau placement; Device:
Fractures
Lateral pin
RCT, efficacy study
placement
NCT00610701
Use of a Reinforced Injectable
Device: Norian
Tibial Fractures
Calcium Phosphate Bone Cement Drillable Bone Void
in the Treatment of Tibial Plateau Filler
Fractures
NCT01132508
The Development of a Surgical
Device: Target Tape Femoral Fracture;
Localizing Aid Medical Device
Tibial Fracture
NCT01300520
New Method for Distal Interlocking Device: The Guiding Fracture; tibia
of Cannulated Intramedullary Nails Star; Device:
Phase I/II: RCT, safety/efficacy fluoroscopy (OEC
study
9800 - General
NCT00648479
Electric)
Rec
Active,
NR
110 Child Apr-10 Nov-12 University of
Adt
Manitoba;
Sen
Orthopedic
Research and
Education
Foundation;
Orthopedic
Trauma
Association
140 Adt Jun-09 Nov-12 AO Clinical
Sen
Investigation and
Documentation;
Synthes Inc.
Rec
140
Adt Apr-11 Apr-12 Smith &
Sen
Nephew, Inc.
Rec
100
Sen
MissouriColumbia
Rec
30
Adt Sep-08 Mar-12 Synthes GmbH; http://ClinicalTrials.gov/show/NCT01132508
Sen
Synthes Asia
Pacific
Not yet 250 Child Mar-11 Dec-11 Aeos Biomedical http://ClinicalTrials.gov/show/NCT01300520
Rec
Adt
Inc.
Sen
Term
10
328
Adt
N/K
Dec-11 Hadassah
Medical
Organization
Plate Fixation of Distal Femur
Device: 95-degree Femoral Fractures
Fractures: A Protocol for a Study Angled Blade Plate;
of Two Plate Options
Device: 4.5mm
Condylar Locking
NCT00644397
Plate
Functional Outcome and MRI of
Device: Femoral
Femoral Shaft
Muscle Damage Following Nailing Nailing with Different Fracture
Procedure in Femur (Thigh)
Entry Points
Fractures Using Different Entry
Points
efficacy study
NCT00471913
Intramedullary Nailing of the
Device: Antegrade Femur Fracture
Femur:Trochanteric vs Piriformis Intramedullary Nail;
Starting Portals
Device: Trigen
RCT, efficacy study
Trochanteric Femoral
NCT00593333
Nail
Randomized, Prospective
Device: Synthes
Femur Fracture
Comparison of Two Femoral
Reamer-IrrigatorReaming Systems
Aspirator (RIA);
RCT, efficacy study
Device: Zimmer
NCT00594438
Sentinel Reamer
Pulsed Ultrasound to Speed-up
Pulsed, lowClosed or I° open
Healing after Intramedullary nailing energetic ultrasound fractures of the tibia
of Tibia fractures
(Exogen, Smith &
RCT, efficacy study
Nephew); usual care
ISRCTN90844675
Continuous Pressure Monitoring In
Lower Leg Fractures
RCT, efficacy study
NCT00358514
Natural History of Anterior
Compartment Pressures of the
Thigh Following Femur Fracture
NCT00919464
Rec
Comp
60
Adt
Active,
NR
116
Active,
NR
20
Sen
Alabama at
Birmingham;
Smith &
Nephew, Inc.
Alabama at
Birmingham;
Synthes Inc.
Comp
250
Device: Continuous Compartment
Compartment
Syndrome
Pressure Monitoring
Term
Device: Pressure
monitoring device
Term
Femur Fracture
100 Child May-06 Jul-11 MetroHealth
Adt
Medical Center
Sen
Apr-07 Apr-11 University of
British Columbia
Adt Oct-08 Oct-10 German
Employer's
Liability
Insurance for the
Administrative
Professions
(Germany)
250 Child Sep-08 Mar-10 University of
Adt
British Columbia
Sen
7
329
Adt Apr-06 Jan-10 CAMC Health
Sen
System
Effect of C1-esterase Inhibitor on Drug: C1-esterase Trauma;
Systemic Inflammation in Trauma inhibitor; Other:
Inflammation;
Patients With a Femur Fracture
Saline 0.9%
Sepsis; Multiple
Phase III: RCT
Organ Dysfunction
NCT01275976
Syndrome
Study of AMG 785 in Tibial
Drug: AMG 785
Fracture Healing
Diaphyseal Fractures Status Post 210mg; Drug: AMG
Intramedullary Nailing
785 70mg; Drug:
AMG 785 140 mg;
study
Drug: Placebo
NCT00907296
Efficacy of strontium ranelate in
Strontium ranelate Lower limb fracture,
the management of limb fractures
osteoporosis
in osteoporotic patients
efficacy study
ISRCTN60251236
Safety and Efficacy of I 0401 in the Drug: I-0401 (a new Tibia Plateau
Treatment of Tibial Plateau
bone graft substitute) Fractures
Fractures Requiring Grafting
study
NCT00409799
Pain; Opiate; upper
A Dosing and Efficacy Study of
Drug: sufentanil
or lower extremity
Intra-nasal Sufentanil for Moderate
fracture
to Severe Pain
NCT01012999
Study Of Tranexamic Acid For The Drug: Tranexamic
Femoral Fractures
Reduction Of Blood Loss In
Acid plus standard of
Patients Undergoing Surgery For care; Procedure:
Long Bone Fracture
Standard of care
NCT00824564
Not yet
Rec
70
Adt May-11 Oct-14 UMC Utrecht;
Sen
Sanquin
Rec
400
Adt Sep-09 Oct-13 Amgen
Sen
Comp
40
Adt Jun-10 Dec-11 Institut de
Recherches
Internationales
Servier (France)
Active,
NR
180
Adt Nov-06 Sep-11 Kuros
Sen
Biosurgery AG
Term
16
Adt Nov-09 Mar-11 University of
Sen
Utah
Comp
82
Adt
330
Apr-09 Jun-10 Pfizer
ACTiF- Assessment of Closed
Tibial Fractures
NCT00533377
Drug: CP-533, 536; Tibial Fractures
Drug: Placebo;
Procedure: Standard
of Care; Drug: CP533,536; Drug: CP533,536; Drug: CP533,536
A Phase 2/3 Multicenter,
Drug: rhBMP-2/CPM; Fractures,
Controlled Trial Of rhBMP-2/CPM Drug: rhBMP-2/CPM; diaphyseal tibial
In Tibial Fractures
Drug: rhBMP-2/CPM; fracture
Phase II/III: RCT, safety study
Drug: rhBMP-2/CPM
NCT00387686
Procedure
Wound management of Open
Lower Limb Fractures (WOLLF)
RCT
ISRCTN33756652
Comparison of BioCart™II With
Microfracture for Treatment of
Cartilage Defects of the Femoral
Condyle
study
NCT00729716
Femoral Bone Metastases
NCT01428895
Comp
276 Child Jan-08 May-10 Pfizer
Adt
Sen
Term
367
Active
460 Child Mar-12 Mar-17 University of
Adt
Warwick (UK)
Sen
Adt Nov-06 Mar-10 Wyeth is now a
Sen
wholly owned
subsidiary of
Pfizer
Negative-pressure
wound therapy;
Standard dressing
Open fractures of
the lower limb
Procedure:
BioCart™II;
Procedure:
Microfracture
Symptomatic
Cartilage Defects of
the Femoral Condyle
Rec
40
Child May-08 May-15 ProChon Biotech http://ClinicalTrials.gov/show/NCT00729716
Adt
Ltd
Procedure: Surgery Cancer; Metastatic
Alone; Other:
Malignant Neoplasm
Combined Surgery to Femur; Risk of
and Radiation
Fracture
therapy
M.I.P.O. vs Intramedullary Nailing Procedure: Minimally Tibia Fracture
in Tibia Fractures
Invasive Plate
RCT
Osteosynthesis;
NCT01047826
Procedure:
intramedullary tibial
Nailing
Standard Reaming Versus
Procedure: Standard Femoral Fractures
Reaming/Irrigating/Aspirating for Reaming; Procedure:
Intramedullary Nailing of Femoral Reaming/Irrigating/A
Shaft Fractures
spirating
RCT
NCT00534326
Rec
180
Adt Mar-09 Mar-15 University Health http://ClinicalTrials.gov/show/NCT01428895
Sen
Network,
Toronto
Rec
180
Adt Dec-10 Dec-14 King Abdullah
International
Medical
Research Center
Invite
550
Adt Dec-06 Dec-14 Greenville
Sen
Hospital System
University
Medical Center
331
Assessment of Fixation Strategies
for Severe Open Tibia Fractures
Phase III: RCT
NCT01494519
Nails Versus Plates for Femur
Fractures in Dar es Salaam,
Tanzania
NCT01548456
Procedure: Surgery
with an external ring
fixator; Procedure:
Definitive fixation
with a locked IM nail
or plate
Procedure:
Intramedullary
Nailing; Procedure:
Open Reduction
Internal Fixation
Severe Open
Fractures of the
Tibia (Shin) Bone
Femoral Fractures
Rec
624
Not yet 333
Rec
Types of Fixation of Vancouver B1
Periprosthetic Fractures
RCT
NCT01354535
Adt
Jul-11 Oct-14 Major Extremity http://ClinicalTrials.gov/show/NCT01494519
Trauma
Research
Consortium;
Department of
Defense
Adt Jul-12 Jul-14 University of
California, San
Francisco;
Orthopaedic
Research
Foundation;
Orthopaedic
Trauma
Association;
Muhimbili
Orthopaedic
Institute
Adt Jun-12 Jun-14 St. Michael's
Sen
Hospital,
Toronto
Procedure: Isolated Femur Fractures
Not yet 89
Locked Compression
Rec
Plate; Procedure:
Cable Plating and
Strut Allograft with
Cerclage Wiring
Hyperbaric Oxygen in Lower Leg Procedure:
Tibial Fracture; Soft
Rec
120 Adt Feb-06 Dec-13 Bayside Health
Trauma
Hyperbaric
Tissue Injury
Sen
Phase II/III: RCT, efficacy study Oxygenation
NCT00264511
Using autologous mesenchymal
mesenchymal stem Tibial Fracture, non- Active 60
Adt Jan-10 Dec-13 Joint UCLH and
stem cells (MSC) to treat human cells; bone marrow union
Sen
UCL Biomedical
fractures
Research Unit
RCT
(UK)
ISRCTN09755245
Percutaneous Autologous Bone- Procedure:
Tibial Fractures;
Rec
186 Child Sep-07 Sep-13 University
marrow Grafting for Open Tibial
Osteosynthesis
Fractures, Open;
Adt
Hospital, Tours
Shaft Fracture
Bone Marrow
Sen
RCT, efficacy study
Transplantation
NCT00512434
332
Efficacy Study of Surgical
Technique in Intramedullary Tibia
Nailing, Using Trigen META Tibia
Nails
study
NCT01358292
Anterolateral Versus Posterior
Approach for Total Hip
Arthroplasty After Displaced
Femoral Neck Fracture
RCT, efficacy study
NCT01484405
Suprapatellar Versus Infrapatellar
Nailing in Tibial Fractures: A Pilot
Study
RCT, efficacy study
NCT01341418
Distal Locking Using an
Electromagnetic Field Guided
Computer Based Real Time
System for Orthopaedic Trauma
Patients
RCT, efficacy study
NCT01183078
(FLOW)
RCT
ISRCTN33993149
Procedure: Semiextended Surgical
Technique
Tibial Fractures
Rec
200
Adt Feb-11 Jul-13 Smith & Nephew http://ClinicalTrials.gov/show/NCT01358292
Sen
Orthopaedics
AG
Procedure: posterior Femur Fracture
approach;
Procedure:
anterolateral
approach
Rec
64
Procedure:
Suprapatellar
approach;
Procedure:
Infrapatellar
approach
Procedure: freehand; Procedure:
Wand technique
Rec
40
Active,
NR
48
Adt Jun-10 Jun-13 Florida
Sen
Orthopaedic
Institute;
Orthopaedic
Trauma
Association
Adt Apr-11 Sep-12 Florida
Sen
Orthopaedic
Institute;
Orthopaedic
Trauma
Association
Adt Aug-10 Feb-12 Wake Forest
Sen
University; Smith
& Nephew, Inc.
Tibial Fractures.
Tibial Fractures;
Femoral Fractures
Saline solution at
Open fractures,
gravity pressure (1-2 upper or lower
psi); Saline solution extremity
at low pressure (5-10
psi); Saline solution
at high pressure (>20
psi); Castile soap
solution (80ml per 3
litres saline) at
gravity pressure (1 2 psi); Castile soap
solution at low
pressure (5-10 psi);
Castile soap solution
at high pressure (>20
psi)
Comp 2280 Adt Jun-09 Jan-12 McMaster
Sen
University
(Canada)
333
Comparing Surgical Techniques
for CRIF of Pertrochanteric
Fractures
NCT00686023
Procedure: internal
fixation (DHS richard nail);
Procedure: internal
fixation (inflatable
PFN by DISCOTEC)
A Prospective Randomized
Procedure: BMP-7 in
Controlled Trial on the Use of
adjunct to fresh
Bone Morphogenetic 7 (BMP-7)
frozen allograft;
(OP-1®) and Demineralized Bone Procedure: allograft
Matrix in Tibial Non-union
together with DBM
NCT00551941
Adjunctive Therapy to Treat Tibial Procedure: open
Shaft Fractures
fracture reduction
study
NCT00533793
Pre-drilling or Self Drilling External Procedure:
Fixation Pins
Placement of
external fixation pins
efficacy study
NCT01046747
Autologous Implantation of
Procedure:
Mesenchymal Stem Cells for the autologous
Treatment of Distal Tibial
mesenchymal stem
Fractures
cells implantation
study
NCT00250302
A Study of Immediate and Delayed Procedure: delayed
Closure of Type II and IIIa Open closure; Procedure:
Tibia Fractures
immediate wound
Parallel assignment, efficacy
closure
study
NCT01315392
Femur Fracture
Non-union
Diaphysary Tibial
Fractures
Trauma
Fracture; Dislocation
Tibial Fracture
Not yet 100
Rec
Adt Jun-08 Jan-12 Tel-Aviv
Sen
Sourasky
Medical Center
Rec
30
Sen
Hospital, Ghent
Active,
NR
200
Adt Apr-07 Sep-11 Kuros
Sen
Biosurgery AG;
Baxter
BioScience
Rec
100
Adt
Sen
Jul-09 Aug-11 Temple
University
Comp
24
Adt
Apr-09 Apr-11 Hadassah
Medical
Organization;
Teva
Pharmaceutical
Industries
Type II and IIa Open Comp
Tibia Fractures
451 Child Jul-00 Mar-11 Carolinas
Adt
Healthcare
Sen
System;
Orthopaedic
Trauma
Association;
Orthopaedic
Research and
Education Fund
334
A randomised clinical pilot trial
comparing intramedullary nailing
with plate and screw fixation in the
treatment of patients with an acute
fracture of the distal tibia
RCT
ISRCTN08249684
Comparison Between LISS Plating
and Intramedullary (IM) Nailing for
Supracondylar Femur Fractures
RCT, efficacy study
NCT00578019
Skeletal Versus Cutaneous
Traction For Treatment of Femur
Fractures
RCT, efficacy study
NCT00916136
Intramedullary
nailing; Screw and
plate fixation
Distal tibia fractures
Comp
24
N/K Mar-08 Sep-10 University of
Warwick (UK)
Procedure: IM
Nailing; Procedure:
LISS
Supracondylar
Femur Fracture
Active,
NR
80
Adt Dec-99 Sep-10 University of
Sen
Alabama at
Birmingham
Rec
150
Adt May-09 May-10 Vanderbilt
Sen
University
Rec
460
Sen Mar-10 Jun-15 Karolinska
Institutet
Not yet
Rec
32
Child Apr-08 Apr-11 Imperial College http://ClinicalTrials.gov/show/NCT00632034
Adt
London
Sen
Rec
20
Sen
MissouriColumbia;
Medtronic
Procedure: Femoral Femur Fracture
Traction
Other
Goal Directed Haemodynamic
Other: fluid and
Therapy for Patients With Proximal inotropic support
Femoral Fracture
RCT, efficacy study
NCT01141894
Stem Cells and Tibial Fractures
Other: CD34+
Phase I/II: RCT, safety/efficacy haemopoietic stem
study
cells
NCT00632034
Incisional Vacuum Assisted
Other: 75 mmHg
Closure (IVAC) Device and Its
suction; Other: 125
Effect on Implanted Bone
mmHg
Morphogenic Protein (BMP-2)
RCT
NCT00829621
Pilon Fracture Reduction and
Functional Outcome
NCT01316289
Femoral Fracture
Tibial Fractures
Fractures, Closed;
BMP-2; Incisional
Vacuum Assisted
Closure (IVAC);
Tibial fracture
Pilon Fracture of
Tibia
Not yet 109
Rec
335
Sen
Investigation and
Documentation
A Comparison of Two Injection
Locations in Obese Patients
Having Lower Leg/Foot Surgery
NCT01550094
Onset Time of Nerve Block: A
Comparison of Two Injection
Locations in Patients Having
Lower Leg/ Foot Surgery
NCT01542840
Inflammatory Response Following
Intraarticular Fracture
NCT01514643
Assessment of Severe Extremity
Wound Bioburden at the Time of
Definitive Wound Closure or
Coverage
NCT01496014
Strain of Muscle &/or Rec
Tendon of Lower
Leg; Fracture of
Lower Leg; Crushing
Injury of Lower Leg;
Fracture Malunion
(Ankle &/or Foot);
Complete Tear,
Ankle &/or Foot
Ligament;
Pathological
Fracture (Ankle &/or
Foot); Loose Body in
Joint of Ankle &/or
Foot
Strain of Muscle
Not yet
and/or Tendon of
Rec
Lower Leg; Fracture
of Lower Leg;
Crushing Injury of
Lower Leg; Fracture
Malunion - Ankle
and/or Foot;
Disorder of Joint of
Ankle and/or Foot;
Complete Tear,
Ankle and/or Foot
Ligament;
Pathological
Fracture - Ankle
and/or Foot; Loose
Body in Joint of
Ankle and/or Foot
Tibial Plateau
Active,
Fracture
NR
80
Adt Mar-12 Mar-14 Jose Soberon,
Sen
MD
76
Adt Mar-12 Mar-14 Ochsner Health http://ClinicalTrials.gov/show/NCT01542840
Sen
System
60
Utah
Open Fracture; tibial
fracture
600
Adt Sep-11 Dec-13 Major Extremity http://ClinicalTrials.gov/show/NCT01496014
Trauma
Research
Consortium;
Department of
Defense
Rec
336
The Role of Patient Expectations
in Traumatic Orthopedic
Outcomes-TEFTOM EURASIA
Prospective study
NCT01134354
Early Standardized Weight Bearing
Utilizing Immersion Therapy
Following Periarticular Lower
Extremity Fractures
NCT01457326
Pilon Fracture Reduction and
Functional Outcome
NCT01316289
Tibia Fracture
(Isolated); Ankle
Fracture (Isolated)
Lower Extremity
Periarticular
Fractures
Rec
200
Adt Jun-10 Oct-13 AO Clinical
Sen
Investigation and
Documentation
Invite
130
Adt Jun-09 May-13 University of
Sen
Utah
Pilon Fracture of
Tibia
Not yet 109
Rec
Sen
Investigation and
Documentation
Interventions
Conditions
Recruit
n
Device: Open
implantation of
INFUSE Bone Graft
(rh BMP-2);
Procedure: Open
implantation of ICBG
Device: C leg
compared to
subject's mechanical
leg (Otto Bock);
Device: C leg
compared to
subject's mechanical
leg (Otto Bock)
Tibial Delayed
Healing
Rec
360
Adt Nov-10 Nov-15 Medtronic Spinal http://ClinicalTrials.gov/show/NCT01016067
Sen
and Biologics
Transfemoral
Amputation;
Unilateral Traumatic
Amputation of Leg at
or Above Knee
Rec
40
Adt Aug-11 Dec-13 Rehabilitation
Sen
Institute of
Chicago; Otto
Bock Healthcare
A11C: OTHER
Title
CT ID
Device
Tibial Delayed Healing Pivotal
Clinical Trial
study
NCT01016067
Functional Outcomes in
Dysvascular Transfemoral
Amputees
RCT
NCT01537211
337
Age Start
(Grp) Date
End Sponsors
Date
URL
Effects of Shrinker Use on Healing Device: compression
and Volume
shrinker
RCT, efficacy study
NCT00693628
Senza™ spinal cord stimulation
Senza™ spinal cord
system for the treatment of chronic stimulation system
back and leg pain in failed back
surgery syndrome (FBSS) patients
RCT
ISRCTN33292457 SS) patients
Study to Evaluate the Safety and Device: GelrinC
Performance of Treatment of
Articular Cartilage Lesions Located
on the Femoral Condyle With
gelrinC
NCT00989794
Strength, Pain and Function in
Device: NMES
Operation Iraqi Freedom/Operation (EMPI 300PV
Enduring Freedom Amputees: A stimulator) plus
Nurse-Managed Program
standard of care
RCT
NCT00942890
Transtibial
Amputation
Rec
100
Adt Mar-07 Jan-13 University of
Sen
Oklahoma
Chronic back and
leg pain in failed
back surgery
syndrome (FBSS)
patients
Active
20
Adt Apr-11 Dec-12 Nevro
Sen
Corporation
(USA)
Femoral Condyle
Lesion
Rec
25
Adt Sep-09 Dec-12 Regentis
Biomaterials
Transtibial
Amputation
Rec
60
Adt
Evaluation of a Pro-Active
Dynamic Accommodating Socket
study
NCT01546311
Amputation
Rec
5
Adt
Sen
Use of an Interactive Video Game Device: Nintendo Wii Below Knee
as Part of a New Amputee
fit ™ balance board Amputation
Rehabilitation Program
NCT01131819
Rec
10
Adt
Sen
Device: Pro Active
Dynamic
Accommodating
Socket
338
Apr-09 Dec-12 University of
North Carolina,
Charlotte; Walter
Reed National
Military Medical
Center; United
States Naval
Medical Center,
San Diego
Jan-12 Dec-12 Infoscitex
Corporation;
Liberating
Technologies,
Inc;
Telemedicine
and Advanced
Technology
Research Center
(TATRC)
May-10 Sep-12 University of
British Columbia
Comparison of Two Under Knee Device:
Lower Limb Bypass
endothelialised
Types:Endothelialised Prosthesis prosthesis
Versus Autologous Vein Graft
Phase II: RCT
NCT00221806
Arteritis
Evaluation of the Development of Device: Novel
Evaluation of a New
an Advanced, Conformable
conformable woven Prosthetic Socket
Prosthetic Socket, Study II
inner socket
Liner Material
study
NCT01455324
Temporary Prosthesis in Traumatic Device: Temporary
Below-knee Amputation
tuber-ischii bearing
Phase II: RCT, efficacy study;
prosthesis
NCT00263497
Clinical Evaluation of Direct
Manufactured Prosthetic Sockets
NCT01155024
Transtibial
Amputation
Device: Traditional Amputation
fabricated prosthetic
socket; Device:
Direct manufactured
(DM) prosthetic
socket
Rec
40
Comp
1
Rec
20
Comp
10
339
Sen
Hospital,
Bordeaux;
Ministry of
Health, France;
W.L.Gore &
Associates
Adt Sep-11 Dec-11 Infoscitex
Sen
Corporation;
U.S. Army
Medical
Research and
Materiel
Command;
Mayo Clinic
Child Mar-06 Dec-11 University
Adt
Hospital of North
Norway; Medical
University of
Joenkoeping,
Sweden;
NCHADS Ministry of
Health of
Cambodia
Adt Sep-10 Sep-11 Ohio Willow
Sen
Wood;
Department of
Defense
The Effect of Reducing Soreness
in Marathon Runners
RCT, efficacy study
NCT01512082
Device: Pulsed
Soreness in Muscles Comp
electromagnetic field
devices; Device:
Pulsed
electromagnetic field
devices
133
Comparison of Two Lower Limb
Bypass Types : Prosthesis Versus
Autologous Vein
NCT00221715
Device:
Arteritis; Diabetes
femoropopliteal
artery bypass;
Device:
femoropopliteal
artery bypass
Device: Monitoring of Compartment
StO2
Syndrome
Comp
100
Comp
120 Child Sep-09 Apr-11 University
Adt
Hospital
Sen
Birmingham
NHS Foundation
Trust
Device: adaptive
prosthetic socket
Active,
NR
60
Sen
Wisconsin,
Milwaukee
Rec
90
Adt
The Application of Near Infrared
Spectroscopy (NIRS) in the
Detection of Lower Limb
Compartment Syndrome
NCT00921271
Dynamic Management of Excess
Residual Limb Pressure With New
Smart Socket Technology
NCT01108536
Study of New Catheter & Pressure
Monitor System to Help Prevent
Compartment Syndrome From
Developing in the Injured Leg
NCT00681616
Amputation
Device:
Compartment
Compartment
Syndrome
Monitoring System
(CMS); Device:
Compartment
Monitoring System
with Active Fluid
Removal; Device:
Compartment
Monitoring System
without fluid removal
340
Adt Aug-11 Aug-11 Northern
Sen
Orthopaedic
Division,
Denmark;
Department of
Geriatrics,
Aalborg
Hospital, Aarhus
University,
Denmark;
Department of
Rheumatology,
Aalborg
Hospital, Aarhus
University,
Denmark
Adt Jul-02 May-11 University
Sen
Hospital,
Bordeaux;
Ministry of
Health, France
Jan-09 Dec-10 Twin Star
Medical, Inc.;
Department of
Defense
Medico Economic Evaluation of
Dermal Substitute Integra® for
Coverage of Inferior Limb
Traumatic Skin Loss
study
NCT00906672
Dressing Study
RCT, efficacy study
NCT01366105
Metabolic Cost Savings for
Transtibial Amputees Wearing the
CESR Foot
Phase III: RCT, efficacy study;
NCT00494143
Local Infiltration Versus Block
Against Pains After High Tibial
Osteotomy
study
NCT01537146
Evaluation of Continuous
Saphenous Nerve Block to
Supplement a Continuous Sciatic
Nerve Block After Ankle Surgery
RCT, efficacy study
NCT01167907
Intraoperative Methadone vs
Morphine for Postoperative Pain
Control in Patients Undergoing
Surgery of the Tibia
RCT, efficacy study
NCT01430182
Prophylactic Phenylephrine
Infusion for Preventing
Hypotension During Spinal
Anesthesia
study
NCT01533662
Device: INTEGRA®; Leg Injuries; Ankle
Procedure: Flap
Injuries; Foot Injuries
technique
Rec
120
Adt Jun-09 Nov-10 University
Sen
Hospital,
Bordeaux
Comp
106
Sen
University
Device: CESR
Transtibial
Prosthetic Foot;
Amputation
Device: typical
prosthetic foot;
Device: standardized
prosthetic foot
Active,
NR
20
Adt
Sen
Drug: Ropivacaine;
Drug: Ropivacaine
Osteoarthritis;
Malalignment
Active,
NR
60
Adt Feb-12 Jun-14 Northern
Sen
Orthopaedic
Division,
Denmark
Drug: 0.2%
ropivacaine; Drug:
saline
Orthopedic Surgery
of Lower Extremity
Rec
74
Adt
Sen
Jul-12 Wake Forest
University; IFlow
Drug: Methadone;
Drug: Morphine
Pain, Postoperative
Active,
NR
60
Adt Sep-11 Mar-12 Baylor College
of Medicine
Rec
64
Sen
Hospital,
Toulouse
Device: V.A.C. by
K.C.I.
Surgical Wound
Infection
Drug: phenylephrine Orthopedic Surgery
infusion; Drug:
of Lower Limb
patients receiving
saline infusion
341
Jul-07 Jun-10 Department of http://ClinicalTrials.gov/show/NCT00494143
Veterans Affairs;
University of
Michigan
Jul-10
Study of Platelet-rich Plasma in
Biological: platelet
Cartilage
Comp 50
Treating Patients With
rich plasma injection Degeneration
Tibiofemoral Cartilage
Degeneration
NCT01418755
Effects of Dexmedetomidine on
Drug:
Orthopedic/Podiatry Wdrwn 80
Tourniquet Pain Associated With Dexmedetomidine
Procedures
Lower Extremity Surgeries Under Hcl infusion; Drug:
General Anesthesia
normal saline
NCT00932386
A randomised, placebo controlled Perineural saline;
Elective lower limb
Comp 180
trial of levobupivacaine or the
Perineural
amputation
combination of levobupivacaine
levobupivacaine 1.25
and clonidine when administered mg/ml; Perineural
as a sciatic perineural infusion for levobupivacaine 1.25
the prevention of phantom limb
mg/ml and clonidine
pain after lower limb amputation
1 mg/ml
RCT, efficacy study
ISRCTN31319378
Comparison of Postoperative
Drug: Fentanyl;
Post Operative Pain Comp 90
Analgesic Effect of Intrathecal
Drug:
Magnesium and Fentanyl Added to placebo(distilled
Bupivacaine in Patients
water); Drug:
Undergoing Lower Limb
magnesium sulphate
Orthopedic Surgery
study
NCT01205997
Prospective, double-blind,
Perineural infusion of Lower limb
Comp 62
randomised trial to assess the
levobupivacaine 1.25 amputation
efficacy of continuous
mg/ml; placebo
sciatic/posterior tibial nerve
blockade via a neural sheath
catheter in lower limb amputees
RCT (placebo), efficacy study
ISRCTN68691928
342
Adt Jan-09 Jul-11 Komzak Martin, http://ClinicalTrials.gov/show/NCT01418755
Sen
M.D.
Adt
Sen
Jul-09
Medicine and
Dentistry New
Jersey
Adt Mar-07 Mar-11 NHS Tayside
Sen
(UK)
Adt Aug-10 Jan-11 Qazvin
University Of
Medical
Sciences
Adt
Sen
Jul-07 Jan-10 University
Hospitals of
Leicester NHS
Trust (UK)
Procedure
Blocks
study
NCT00771862
Intramedullary Femoral Reaming,
Human Study
RCT, efficacy study
NCT01042132
Procedure:
Amputation;
Active,
NR
Stump Pain
18
Procedure: the effect
of delayed
intramedullary
reaming; Procedure:
the reaming of the
femoral canal is
performed with two
different reaming
devices
Procedure:
Chirurgical
procedure
Pulmonary
Active,
Complications;
NR
Organ Failure;
Systemic
Inflammatory
Response Syndrome
36
Tibia or Femur
Pseudo-arthrosis
Susp
50
Adt
Amputation;
Phantom Limb;
Stump Pain
Comp
7
Comp
12
Sen
California, San
Diego; Summit
Medical;
National Institute
of General
Medical
Sciences
(NIGMS)
Adt Oct-11 Nov-11 Rigshospitalet, http://ClinicalTrials.gov/show/NCT01449097
Denmark
Monly
Osseous Setting Improvement
With Co-implantation of Osseous
Matrix and Mesenchymal
Progenitors Cells From Autologous
Bone Marrow
assignment
NCT00557635
perineural
ropivacaine
and Stump Pain
RCT, efficacy study
NCT00667264
Adductor-Canal-Blockade Versus
the Femoral Nerve Block Effect on
Muscle Strength and Mobilization
in Healthy Volunteers
NCT01449097
Procedure: Adductor- Muscle Strength;
Canal-Blockade;
Healthy Volunteers
Procedure: The
femoral nerve block;
Procedure: Placebo
343
Sen
California, San
Diego; National
Institute of
General Medical
Sciences
(NIGMS)
Adt May-03 May-12 Ullevaal
University
Hospital
Jan-08 Dec-11 University
Hospital,
ClermontFerrand
Effects of Right Lower Limb
Orthopedic Immobilization on
Braking Function
RCT
NCT01171287
Trial of Nonsurgical Treatment of
Intermittent Claudication Due to
Femoro-Popliteal Disease
RCT
NCT00798850
Procedure: Driving Automobile Driving
Active,
with an Aircast
With an Aircast
NR
Walker; Procedure: Walker; Automobile
Driving with a
Driving With a
walking cast;
Walking Cast
Procedure: Driving
with a running shoe
Procedure:
Femoropopliteal
Active,
Percutaneous
Disease; Intermittent
NR
Transluminal
Claudication
Angioplasty (PTA);
Procedure:
Supervised Exercise
Programme (SEP);
Procedure:
Combined Treatment
Perineural Catheter Insertion
Procedure: Sciatic
Distance for Continuous Peripheral catheter left 0-1cm
Nerve Blocks
past needle tip vs. 5Phase IV: RCT, safety/efficacy 6cm past needle tip
study
NCT00997867
Other
Treadmill Training With Lower
Other: Treadmill
Extremity Amputees
Training
NCT01419288
Use of Near Infrared Spectroscopy Other: Shaving
to Detect Muscle Perfusion in the
Lower Extremity of Uninjured
Subjects
NCT01284023
Assessment of Socket Shapes
Other: Assessed for
Made by Central Fabrication
socket fit
Facilities
NCT01245504
14
Adt Sep-08 Jul-11 Universitaire de http://ClinicalTrials.gov/show/NCT01171287
Sherbrooke;
Fonds de la
Recherche en
Santé du
Québec; BSN
Medical Inc
178 Child Aug-02 Dec-10 University of
Adt
Hull; Hull and
Sen
East Yorkshire
Hospitals NHS
Trust; British
Journal of
Surgery
Research Grant;
European
Society of
Vascular
Surgery
Research Grant
350 Adt Nov-09 Oct-10 University of
Sen
California, San
Diego
Lower Extremity
Surgery; Upper
Extremity Surgery;
Post-operative Pain
Comp
Traumatic
Amputation of Lower
Extremity
Rec
20
Adt Jun-09 Jun-12 Stony Brook
Sen
University
Acute Compartment
Syndrome
Active,
NR
42
Adt Jan-11 Jan-12 J&M Shuler;
Sen
Nonin Medical
People With Lower
Limb Amputation
That Are Ambulatory
Rec
50
Adt Nov-08 Dec-11 University of
Sen
Washington
Fonly
344
A Comparison of External
Mechanical Work Between
Different Prosthetic Feet
RCT
NCT01340807
Segment Transport Versus Acute
Shortening In The Treatment of
Tibial Pseudarthroses With Bone
Loss
study
NCT01246934
Other: Specialized Traumatic
Comp
Functional Prosthetic Amputation of Lower
Training
Extremity
15
Other: Asr Method
Comp
22
Child Oct-09 Feb-10 Bezmialem Vakif http://ClinicalTrials.gov/show/NCT01246934
Adt
University
Rec
30
Child Feb-11 Aug-14 Rambam Health http://ClinicalTrials.gov/show/NCT01255241
Adt
Care Campus
The Effect of Lower Limb
Deformities (LLD) on Children's
Gait and on Energy Expenditure
NCT01255241
Longitudinal Study of Weight
Change Following Lower Limb
Amputation
NCT00932399
The Use of Near Infrared
Spectroscopy in the Diagnosis of
Acute Compartment Syndrome in
Trauma Patients
NCT01547013
To Assess Rotation for Femoral
Version and Tibial Torsion
NCT01531296
Gait Stability of People With
Lower-limb Amputations
NCT00915109
Musculoskeletal Measurements in
Transfemoral Amputees
NCT00909922
Tibia
Pseudoarthroses
Lower Limbs
Deformities; Gait;
Energy Expenditure
Amputation
Anterior Tibial
Compartment
Syndrome
Rotational
Malalignment of the
Lower Extremities
Adt Mar-08 Jan-11 Miami VA
Healthcare
System
Active, 9000 Adt Mar-10 Jun-13 Department of http://ClinicalTrials.gov/show/NCT00932399
NR
Sen
Veterans Affairs
Rec
Monly
130 Adt Feb-12 Feb-13 U.S. Army
Medical
Research and
Materiel
Command
Invite
50
Child Oct-11 Nov-12 University of
Adt
Utah
Gait; Balance
Rec
60
Adt Jun-09 Apr-12 Kim Parker
Sen
Lower Limb Loss
Rec
80
Adt Jan-06 Dec-10 Miami VA
Sen
Healthcare
System
345
A12. GENERAL
A12A: PAEDIATRIC
Title
CT ID
Study to Evaluate the Safety of
Kedbumin 25% Versus Normal
Saline in the Treatment of PostSurgical Hypovolemia in Pediatric
Patients
Phase II/III: RCT, safety study
NCT01531803
Safety and Efficacy of
Palonosetron IV to Prevent
Postoperative Nausea and
Vomiting in Pediatric Patients
study
NCT01395901
Prevention of Post Operative Bone
Loss in Children
RCT, efficacy study
NCT00655681
Interventions
Conditions
Drug: Kedbumin 25% Hypovolemia;
elective cardiac,
abdominal,
orthopedic, or
transplant surgery.
Drug: Palonosetron; Postoperative
Drug: Ondansetron Nausea and
Vomiting
Recruit
n
Age Start
(Grp) Date
Not yet
Rec
60
Child Sep-12 Dec-13 Kedrion S.p.A.
660 Child Jun-11 May-12 Helsinn
Healthcare SA
Rec
Drug: pamidronate;
Other: saline
End Sponsors
Date
URL
Osteoporosis;
Comp 24 Child Sep-07 Aug-11 University of
Cerebral Palsy;
Adt
New Mexico;
Spina Bifida;
Thrasher
Osteopenia;
Research Fund
Osteogenesis
Imperfecta
Measurement of the blood levels of Dyloject® as a single Undergoing routine
Comp 25 Child Jun-10 Jun-11 Central
http://www.controlledthe pain killer diclofenac in children intravenous bolus
surgery including
Manchester
following a single intravenous dose
ear, nose and throat
Foundation Trust
(ENT), orthopaedic,
(CMFT) (UK)
urological and
ISRCTN65890744
general
RCT on Ketorolac and Tramadol in Drug: ketorolac;
Fracture; Pain
Not yet 120 Child Apr-09 Oct-10 IRCCS Burlo
Bone Fractures Pain of Child
Drug: tramadol
Rec
Garofolo
study
NCT00560443
346
Procedure
The Treatment of Type I Open
Fractures in Pediatrics
NCT00870064
Other
Outcomes of Orthopaedic Surgery
Using Gait Laboratory Versus
Observational Gait Analysis in
Children With Cerebral Palsy
NCT00419432
Procedure: Formal Fractures, Open
Operative Treatment;
Procedure:
Emergency
Department
Treatment
Rec
200 Child Mar-10 Mar-14 Children's
Memorial
Hospital
Other: Routine
Cerebral Palsy
Observational
Analysis (prior to
procedure); Other:
Routine
Observational
analysis
supplemented with
Gait Lab Information
(prior to procedure)
Rec
50
Child Jan-07 Oct-14 The Hospital for http://ClinicalTrials.gov/show/NCT00419432
Sick Children
Phalanx of
Active,
Supernumerary Digit
NR
of Hand
50
Child Jul-11 Sep-14 University of
Adt
Utah
Venous
Thromboembolism;
Deep Venous
Thrombosis;
Pediatrics
25
Child May-09 Mar-10 Penn State
Adt
University
Triphalangeal Thumbs in the
Pediatric Population: Long Term
Outcomes Following Surgical
Intervention
Cohort study
NCT01409980
Prevalence and Risk Factors of
Hospitalized Pediatric Patients
NCT01140386
Comp
347
Title
CT ID
Behavioural
Bone Physiology & Mechanics in
Osteomyoplasty Amputation
Rehabilitation
RCT, efficacy study
NCT00271362
Device
A Randomized Controlled Cost
Study of Infuse BMP 2 vs Iliac
Crest Autograft for Non Union of
Long Bone Fractures
study
NCT00856479
The Use of RIA to Harvest Bone
Graft for Treatment of Non-unions
and Fractures
efficacy study
NCT00582439
Antibiotic Prophylaxis in
Orthopaedic Traumatology
RCT
NCT00610987
Methadone Versus Morphine for
Orthopedic Surgery Patients
NCT00892606
Role of Pregabalin in Treatment of
Post-Op Pain in Fracture Patients
RCT, efficacy study
NCT00583869
Interventions
Conditions
Recruit
n
Term
95
Adt Jan-06 Dec-10 Department of http://ClinicalTrials.gov/show/NCT00271362
Sen
Veterans Affairs
Wdrwn
80
Adt Mar-09 Mar-13 Capital District http://ClinicalTrials.gov/show/NCT00856479
Sen
Health Authority,
Canada;
Canadian
Orthopaedic
Trauma Society
Device: ReamerIrrigator-Aspirator
(RIA)
Orthopaedic Trauma Active,
Fractures and NonNR
unions
21
Adt
Jan-07 Dec-10 University of
Alabama at
Birmingham;
Synthes Inc.
Drug: cefazolin;
Drug: Placebo
Fractures, Closed;
Wounds and Injuries
Rec
700
Sen
MissouriColumbia
Drug: Methadone;
Drug: Morphine
Fracture; Pain,
Postoperative
Rec
80
Adt
Jan-09 Dec-11 University of
Louisville
Active,
NR
150
Adt May-07 Aug-11 University of
Sen
Alabama at
Birmingham;
Pfizer
Behavioral:
Amputation;
Amputation
Fracture;
rehabilitation
Inflammation;
exercise program;
Osteoporosis
Procedure:
Osteomyoplasty vs.
routine long posterior
flap
Device: Infuse Bone Non Union
Morphogenic Protein Diaphyseal
(BMP) 2; Procedure: Fractures
iliac crest autograft
Drug: Placebo; Drug: Post-operative Pain
Pregabalin; Drug:
Pregabalin
348
Age Start
(Grp) Date
End Sponsors
Date
URL
Procedure
Effectiveness of Adipose Tissue
Derived Mesenchymal Stem Cells
as Osteogenic Component in
Composite Grafts
study
NCT01532076
Radiation Exposure Using Laser
Guided Fluoroscopy in Various
Orthopaedic Procedures
RCT
NCT00972647
RCT
NCT00788398
Treatment for Open Fractures
RCT, efficacy study
NCT00582361
Procedure:
Osteoporotic
Cellularized
Fractures
composite graft
augmentation;
Procedure: Acellular
composite graft
augmentation
Procedure: Laser
Fractures
beam guidance
Procedure: Saline
Solution; Procedure:
Soap solution;
Procedure: Gravity
Flow Irrigation;
Procedure: Low
Pressure Irrigation;
Procedure: High
Pressure
Procedure: Standard
Wound Dressing;
Device: VAC
Other
Osteogenic Cell Viability in Bone Other: cell viability
Graft Obtained Using the Reamer and osteogenic
Irrigator Aspirator (RIA) System
potential analysis
Versus Iliac Crest Bone Graft
NCT00843973
Reamer Irrigator Aspirator (RIA) vs Other: RIA
Autogenous Iliac Crest Bone Graft harvesting group;
(AICBG) for the Treatment of Non- Other: AICBG
unions
harvesting group
NCT01382485
Not yet 290
Rec
Rec
50
Adt Feb-12 Oct-15 University
Sen
Hospital, Basel,
Switzerland
Adt Aug-09 Jun-11 Loma Linda
Sen
University
2280 Child Jun-09 Dec-12 Greenville
Adt
Hospital System
Sen
University
Medical Center;
McMaster
University;
Department of
Defense
Open Fracture
Wounds
Invite
Orthopaedic
Traumatic Open
Fractures
Comp
63
Adt Jun-01 Jan-10 University of
Sen
Alabama at
Birmingham; KCI
USA, Inc.
Rec
30
Sen
MissouriColumbia; AO
North America
88
Adt
Fractures, Closed
Nonunion of Bone
Not yet
Graft; Fractures Non Rec
Union
349
Jan-12 Jan-14 St. Michael's
Hospital,
Toronto
Prevention of Infection in Surgical
Treatment of Closed Fractures:
Comparative of Cefazolin vs
Vancomycin
NCT01029457
Smoking Cessation in Nonunion,
Malunion, Osseous Infection
NCT00754299
Validation of Laboratory Test for
Predicting Bone Tissue
Regeneration
NCT01362413
Arginine and Nitric Oxide (NO)
Early Prognostic Markers for Nonunion Development
Prospective study
NCT01070576
Closed Fractures
Rec
600
Sen
Tennessee
Fracture Nonunion;
Infection
Wdrwn
60
Adt Oct-10 Oct-12 Penn State
Sen
University
Nonunion of
Fracture
[Pseudarthrosis],
Site Unspecified;
Long bones
Fracture Healing;
Atrophic Non Union
Development;
Hypertrophic Non
Union Development
Rec
30
Adt Jan-11 Dec-13 Istituto
Sen
Ortopedico
Rizzoli
Rec
100
Adt Mar-10 Mar-12 Maastricht
Sen
University
Medical Center
Recruit
n
A12C: OTHER
Title
CT ID
Behavioural
An online aftercare programme to
improve vocational reintegration
after inpatient medical
rehabilitation
RCT, efficacy study
ISRCTN33957202
Interventions
Conditions
Internet-based
Vocationally strained Active
aftercare intervention patients in
+ inpatient
psychosomatic,
rehabilitation;
orthopaedic and
Inpatient rehabilation cardiovascular
only
rehabilitation
800
350
Age Start
(Grp) Date
End Sponsors
Date
Adt Nov-10 Oct-13 German
Sen
Statutory
Pension
Insurance
(Germany)
URL
Ability of Near Infrared
Spectroscopy to Isolate
Compartments of the Extremity
Phase I: Cross-sectional study
NCT01283451
Mind Body Therapy During
Geriatric Rehabilitation
NCT01074788
Device
Evaluation of an Acellular
Osteochondral Graft for Cartilage
LEsions Pilot Trial
study
NCT01183637
Evaluation of the Cartilage
Autograft Implantation System
Treatment for Articular Cartilage
Lesions
study
NCT01508442
Agili-C Bi-phasic Implant
Performances
NCT01471236
Comparison of Bioactive Glass
and Beeta-Tricalcium Phosphate
as Bone Graft Substitute
study
NCT00841152
N/K
Jun-11 J&M Shuler
Behavioral: Muscle
contraction
Acute Compartment
Syndrome
Active,
NR
63
Adt
Sen
Behavioral: mind
body therapy
Patients Who Are in Active,
Need of Short or
NR
Long Term
Rehabilitation Due to
Neurological Event
(Mainly Stroke) or
Post Orthopedic
Surgery
30
Adt Nov-09 Nov-10 Tel-Aviv
Sen
Sourasky
Medical Center
Device: Kensey
Articular Cartilage
Nash Corp. Cartilage Injury
Repair Device;
Procedure:
Microfracture
Active,
NR
30
Adt Jun-10 Apr-16 Kensey Nash
Sen
Corporation
Device: Cartilage
Articular Cartilage
Autograft
Lesions
Implantation System
(CAIS); Procedure:
Microfracture
Rec
12
Adt
Apr-11 May-15 The Hawkins
Foundation;
DePuy Mitek
Device: Agili-C BiCartilage and
phasic Implant;
Ostheochondral
Procedure: miniDefects
arthrotomy or
arthroscopy
Device: Bioactive
Bone Neoplasm
glass granules
(Bonalive); Device:
Beeta-tricalcium
phosphate
(ChronOs);
Procedure: Autograft;
Procedure: Allograft
(frozen femoral
head)
Rec
20
Adt
Jun-11 Aug-14 Cartiheal (2009) http://ClinicalTrials.gov/show/NCT01471236
Ltd
Rec
180
Adt Mar-09 Dec-13 Turku University http://ClinicalTrials.gov/show/NCT00841152
Sen
Hospital
351
Sutures Versus Staples for Wound Device: Sutures;
Closure in Orthopaedic Surgery
Device: Staples
RCT, efficacy study
NCT01146236
Surgical Wound
Infection
Rec
2560 Adt
Sen
Manitoba;
Manitoba
Institute for
Patient Safety;
Manitoba
Medical Services
Foundation;
Alexander
Gibson Fund
Adt Mar-10 Sep-13 InSightec
Sen
Focused Ultrasound Surgery in the Device: ExAblate
Bone Cancer; Bone
Rec
50
Treatment of Pain Resulting From 2100
Metastases; Pain
Metastatic Bone Tumors With the
ExAblate 2100 Conformal Bone
System
study
NCT01085565
Closure of Fasciotomy Wounds: A Device: DermaClose Wounds and
Rec
20
Adt Jul-10
Prospective, Observational Study Continuous External Injuries;
Sen
of a Continuous External Tissue
Tissue Expander;
Compartment
Expander
Device: Vessel loop Syndrome
NCT01171534
ExAblate Conformal Bone System Device: ExAblate
Bone Metastases
Rec
50
Adt Sep-09
Treatment of Metastatic Bone
2100
Sen
Tumors for the Palliation of Pain
study
NCT00981578
Vascular CT Assessment of
Device: Cone Beam Bone Tumors
Rec
20 Child Nov-06
Structural Autograft and Allograft CT Scan
Adt
Healing
Sen
NCT00594776
Device: Near infrared Acute Compartment Not yet 120 Child Sep-11
Spectroscopy in the Diagnosis of spectroscopy (NIRS) Syndrome
Rec
Adt
Acute Compartment Syndrome
NCT01171638
352
MissouriColumbia;
Wound Care
Technologies,
Inc.
Feb-13 InSightec
Jan-13 University of
Rochester;
National
Institutes of
Health
Dec-12 J&M Shuler;
Department of
Defense; Nonin
Medical
Coiled Catheters for Regional
Anesthesia
RCT, efficacy study
NCT01290185
Transcutaneous Electrical Nerve
Stimulation (TENS) and
Fibromyalgia (FM)
RCT
NCT00932360
Device: Placement of Arthritis
different catheters for
continuous nerve
block
Device: Transient
Fibromyalgia
Placebo TENS
(Rehabilicare
Maxima TENS);
Device: Active TENS
(Rehabilicare
Maxima TENS);
Device: No TENS
(Rehabilicare
Maxima TENS)
Device: Window
Pressure Ulcer
A Multi-centre Evaluation of the
Performance of Window Dressings
on Subjects With High Risk
Pressure Ulceration
NCT01438541
ExAblate (Magnetic Resonance- Device: ExAblate
Bone Metastases;
guided Focused Ultrasound
2000; Device: Sham Multiple Myeloma
Surgery) Treatment of Metastatic
Bone Tumors for the Palliation of
Pain
study
NCT00656305
Assessment of Near Infrared
Device: near-infrared Compartment
Spectroscopy as a Diagnostic Tool spectroscopy
Syndrome
in Acute Compartment Syndrome
NCT01077934
Hyaluronic Acid Injection Post
Device: Hyaluronic Cartilage Injury
Arthroscopy - Does it Improve
Acid Injection; Drug:
Immediate Function? Double Blind Saline Injection
Controlled Prospective Study
study
NCT01442571
Rec
152
Adt Apr-11 Aug-12 Sunnybrook
Sen
Health Sciences
Centre
Rec
50
Sen
Iowa; Orthopedic
Section of the
American
Physical
Therapy
Association
Rec
26
Adt Sep-11 Feb-12 Molnlycke
Sen
Health Care AB
Rec
148
Adt Mar-08 Dec-11 InSightec
Sen
Not yet 200 Child Nov-11 Oct-11 J&M Shuler;
Rec
Adt
Emory University
Sen
Not yet 100
Rec
353
Adt
Aug-11 Hadassah
Medical
Organization
Spectroscopy in the Diagnosis of
Acute Compartment Syndrome in
Injured Soldiers
NCT01123798
Bioactive Glass Granules in Filling
of Bone Defects
NCT01304121
Perioperative Temperature
Management
RCT, efficacy study
NCT00617136
Ultrasound Visualization Versus
Electrical Nerve Stimulation
study
NCT01010412
Vagus Nerve Stimulation for
Treating Adults With Severe
Fibromyalgia
study
NCT00294281
Device: near-infrared Acute Compartment
spectroscopy
Syndrome
Comp
300
Adt Feb-10 Jan-11 J&M Shuler;
Department of
Defense;
Somanetics
Corporation
Device: Bioactive
glass (SP53P4)
Comp
48
Adt Oct-06 Dec-10 Turku University http://ClinicalTrials.gov/show/NCT01304121
Sen
Hospital
Rec
279
Adt Apr-08 Dec-10 VU University
Sen
Medical Center
Rec
450
Adt Feb-09 Sep-10 Allentown
Sen
Anesthesia
Associates;
SonoSite, Inc.
Comp
14
Adt
Bone Tumors
Device:
Hypothermia
Intraoperative
warming (Bair
Hugger); Device:
Pre- and
intraoperative
warming (HotDog);
Device:
Intraoperative
warming (HotDog)
Device: Ultrasound Trauma to the Arm,
(Sonosite Titan TShoulder, Elbow,
shaped ultrasound Forearm, or Hand
probe); Device:
Electrical Nerve
Stimulation
(Stimuplex (B Braun)
needle)
Device: Vagus Nerve Fibromyalgia
Stimulation (VNS)
Therapy
354
Oct-06 Jun-10 University of
Medicine and
Dentistry New
Jersey; National
Institute of
Arthritis and
Musculoskeletal
and Skin
Diseases;
National Institute
of Neurological
Disorders and
Stroke (NINDS)
Dietary supplements
Muscle Regrowth During Physical
Rehabilitation and Amino Acid
Supplementation
RCT
NCT00760383
Dietary Supplement: Osteoarthritis
Essential amino
acids; Dietary
Supplement: Alanine
Testing the Effect of Crustacean's Dietary Supplement: Skeletal Deformities;
Gastrolith Nutraceutical on
gastrolith calcium
Leg Length
Mineralization Rate During
Discrepancy
Distraction Osteogenesis
Phase I: Non-randomized, single
group assignement,
NCT01087437
Neocartilage Implant Phase III
Trial
NCT01400607
A Study of Pre-Operative
Treatment of Newly-Diagnosed,
Surgically-Resectable
Osteosarcoma With Doxorubicin,
Ifosfamide, Etoposide, and
Cisplatin With Early Metabolic
Assessment of Response
NCT01258634
Randomized Controlled Trials of
the Effects of Decadron on
Swallowing, Airway, and
Arthrodesis
study
NCT01065961
Rec
60
Rec
Biological:
Articular Cartilage
Rec
Neocartilage
Disorder;
Implant/DeNovo® ET Degeneration;
(Engineered Tissue Articular Cartilage;
Graft); Other:
Chronic Cartilage
Microfracture
Injury; Acute
Cartilage Injury;
Defect of Articular
Cartilage
Drug: Dexrazoxane; Osteosarcoma; Lung Term
Drug: Doxorubicin; Metastases
Drug: Cisplatin;
Drug: G-CSF; Drug:
PEG-filgrastim; Drug:
Etoposide; Drug:
Ifosfamide; Drug:
Mesna; Drug:
Leucovorin
225
Drug: Decadron;
Drug: Saline
200
Swallowing
Rec
2
355
Adt Jun-08 Aug-13 Eunice Kennedy http://ClinicalTrials.gov/show/NCT00760383
Sen
Shriver National
Institute of Child
Health and
Human
Development
Child Jan-11 Dec-11 Hadassah
Adt
Medical
Organization;
Amorfical
Adt
Jul-11
Jul-19 ISTO
Technologies,
Inc.; Zimmer,
Inc.
Child Jul-10 May-18 University of
Adt
Chicago
Adt Nov-08 Nov-16 Albany Medical
Sen
College
Post Market Study of DeNovo NT,
Natural Tissue Graft
NCT00791245
A Study to Determine the Activity
of SCH 717454 in Subjects With
Relapsed Osteosarcoma or
Ewing's Sarcoma (Study
P04720AM3)
NCT00617890
Efficacy of Local Powder
Prophylactics
NCT01372371
Biological:
Cartilage Repair
Particulated Juvenile
Cartilage Allograft
Active,
NR
25
Drug: SCH 717454
(19D12)
Active,
NR
249 Child Feb-08 Aug-13 Schering-Plough http://ClinicalTrials.gov/show/NCT00617890
Adt
Sen
Rec
1844 Child Jun-11 Jun-13 Ganga Hospital http://ClinicalTrials.gov/show/NCT01372371
Adt
Sen
Biological:
Vancomycin;
Biological:
Vancomycin and
Gentamycin;
Biological:
Cefuroxime
Pre- Versus Post-incisional
Drug: Pregabalin;
Pregabalin for Postoperative Pain Drug: Pregabalin
Attenuation and Analgesics Spare
in Orthopedic Oncologic Patients
RCT
NCT01359059
Study of Melatonin on Sleep, Pain, Drug: Melatonin;
and Delirium After Joint
Drug: Placebo
Replacement Surgery
NCT01505465
NeoCart Phase 2 Clinical Trial
Biological: NeoCart;
Procedure:
study
microfracture
NCT00548119
Osteosarcoma;
Sarcoma, Ewing's;
Peripheral
Neuroectodermal
Tumor
Infection
Postoperative Pain
Adt
Jan-06 Dec-13 Zimmer
Orthobiologics,
Inc.
Not yet
Rec
80
Adt Jun-11 Jun-13 Tel-Aviv
Sen
Sourasky
Medical Center
Postoperative Pain; Not yet
Delirium; Confusion;
Rec
Sleep
50
Adt Feb-12 Feb-13 Hospital for
Sen
Special Surgery,
New York
Articular Cartilage
Damage
30
Adt Dec-06 Jan-13 Histogenics
Corporation
Active,
NR
356
Combination Chemotherapy
Before and After Surgery in
Osteosarcoma
Phase II
NCT00019864
Biological: filgrastim; Cardiac Toxicity;
Drug: cisplatin; Drug: Sarcoma
dexrazoxane
doxorubicin
leucovorin calcium;
Drug: methotrexate;
Procedure: adjuvant
therapy; Procedure:
conventional surgery;
Procedure:
neoadjuvant therapy
Acute Pain and Inflammation After Drug: 1 Ketorolac
Acute Pain; Pain
Surgery
intraarticular; Drug: Relief
Phase IV: RCT,
Placebo
study
NCT00774540
Treatment of Methicillin-sensitive Drug: association of Osteoarticular
Staphylococcus Aureus (MSSA) RIFAMPIN +
Infection
RCT
CLINDAMYCIN;
NCT01500837
Drug: association of
LEVOFLOXACIN+
CLINDAMYCIN
Echo-Doppler Assessment of the Drug: Enoxaparin
Deep Vein
Occurrence of Asymptomatic DVT
Thrombosis;
in Orthopedic Replacement
Enoxaparin;
Surgery Under Enoxaparin
Anticoagulants
study
NCT01354704
Open Label Trial of NanoDOX
Drug: NanoDOX
Orthopedic Trauma
Hydrogel in Orthopedic Trauma
Hydrogel; Other:
Wounds
Wounds With and Without Vacuum VAC Alone
Assisted Closure Therapy
study
NCT01518491
Active,
NR
100 Child Mar-00 Dec-12 National Cancer http://ClinicalTrials.gov/show/NCT00019864
Adt
Institute (NCI)
Rec
40
Adt Aug-08 Dec-12 Oslo University
Sen
Hospital
Active,
NR
23
Adt Oct-10 Dec-12 Assistance
Sen
Paris
Rec
240
Adt Mar-11 Dec-12 Les Laboratoires http://ClinicalTrials.gov/show/NCT01354704
Sen
des
Médicaments
Stériles; Hospital
Charles Nicolle
Tunis.
Not yet
Rec
24
Adt Apr-12 Dec-12 Nanohttp://ClinicalTrials.gov/show/NCT01518491
Sen
therapeutics,
Inc.; Department
of Defense
357
Biological: filgrastim; Sarcoma
Active, 44
Adt Aug-01 Oct-12 City of Hope
Drug: dexrazoxane
NR
Medical Center;
National Cancer
doxorubicin
Institute (NCI)
ifosfamide; Drug:
irinotecan
hydrochloride;
Genetic: protein
expression analysis;
Other:
immunoenzyme
technique;
Procedure: adjuvant
therapy; Procedure:
Procedure:
neoadjuvant therapy;
Radiation: radiation
therapy
Lusedra (Fospropofol Disodium) Drug: Fospropofol
Procedural Sedation; Susp 150 Adt Feb-11 Oct-12 Mayo Clinic;
for Minimal to Moderate Sedation disodium; Drug:
Regional Anesthesia
Sen
Eisai Inc.
for Regional Anesthesia Block
Fospropofol
Block; Orthopedic
Prior to Orthopedic Surgery
disodium; Drug:
Surgery
Placebo +
NCT01195103
Midazolam
Prevention of Surgical Site
Drug: mupirocin
Surgical Site
Rec 3000 Adt Mar-11 Sep-12 3M
Infection; hip, knee,
Infections: Effectiveness of Nasal calcium ointment,
Sen
Povidone-Iodine and Nasal
2%; Drug: Povidone- shoulder and elbow
arthroplasty surgery
Mupirocin
iodine solution 5%
Phase IV: RCT
w/w (0.5% available and primary spinal
fusion surgery
NCT01313182
iodine) Patient
Preoperative Skin
Preparation
DVT Prophylaxis in Orthopaedic Drug: Dalteparin
Bone Cancer
Active, 70
Adt Jul-06 Jul-12 M.D. Anderson
Oncology Patients - A Safety
NR
Sen
Cancer Center;
Study
Pfizer
NCT00525057
Combination Chemotherapy and
Dexrazoxane Followed by Surgery
and Radiation Therapy in Treating
Patients With Advanced Soft
Tissue Sarcoma or Recurrent
Bone Sarcoma
Phase II
NCT00544778
358
Phase II Dose-ranging Study of
APD421 in PONV
study
NCT01510704
Surgical Surveillance Trial to
Evaluate a Shortened Infusion
Time of Intravenous Ibuprofen
study
NCT01334957
Double-Blinded Clinical Trial Using
Apatone®B for Symptomatic
Postoperative Total Joint
Replacements
study
NCT01272830
Combination Chemotherapy in
Treating Patients With Stage III or
Stage IV Malignant Peripheral
Nerve Sheath Tumors
Phase II
NCT00304083
Drug: APD421; Drug: Postoperative
Placebo
Nausea and
Vomiting; elective
surgery requiring
overnight stay
Drug: Intravenous
Pain
ibuprofen
Rec
200
Adt Jan-12 Jun-12 Acacia Pharma http://ClinicalTrials.gov/show/NCT01510704
Sen
Ltd
Rec
300
Adt Jun-11 Jun-12 Cumberland
Sen
Pharmaceuticals
Drug: Placebo; Drug: Edematous;
Apatone®B
Synovitis; Foreign
Body Reaction;
Osteolysis
Rec
60
Adt Oct-10 Jun-12 Summa Health http://ClinicalTrials.gov/show/NCT01272830
Sen
System; Crystal
Clinic
Orthopaedic
Center LLC
74
Child Dec-05 Apr-12 Sarcoma
Adt
Alliance for
Sen
Research
through
Collaboration;
National Cancer
Institute (NCI)
Biological: filgrastim; Neurofibromatosis
Rec
Drug: doxorubicin
Type 1; Sarcoma
etoposide; Drug:
ifosfamide;
Procedure:
therapy
Observation, Radiation Therapy, Drug: doxorubicin
Childhood Malignant Active,
Combination Chemotherapy,
hydrochloride; Drug: Fibrous Histiocytoma NR
and/or Surgery in Treating Young ifosfamide; Other:
of Bone; Sarcoma
Patients With Soft Tissue Sarcoma clinical observation;
Phase III
Procedure:
NCT00346164
therapeutic
therapy
Rosuvastatin for Preventing Deep Drug: Rosuvastatin Deep Vein
Rec
Vein Thrombosis
20mg/d for 14days; Thrombosis;
Phase IV: RCT, safety/efficacy Drug: enoxaparin
Venous;
study
only
Thrombosis;
NCT01021488
Prevention
600 Child Feb-07 Mar-12 Children's
Adt
Oncology Group;
National Cancer
Institute (NCI)
180
359
Adt Oct-09 Mar-12 Hallym
Sen
University
Medical Center
How Lidocaine Affects Outcomes
In Orthopedic Surgery Patients
NCT01179100
Traumeel S for Reduction of Post
Operative Pain Following
Arthroscopy
NCT00307892
Oral Versus Intravenous
Antibiotics for Bone and Joint
Infections (OVIVA B&J)
study
NCT00974493
Drug: Lidocaine
Orthopedic; Surgery; Invite
Elderly
100
Adt Jun-11 Feb-12 Cedars-Sinai
Sen
Medical Center
Drug: Traumeel S:
intra-operative
irrigation + oral
ingestion; Drug:
Placebo
Drug: Antibiotics
Post-operative Pain
Susp
98
Adt
Jan-11 Jan-12 Shaare Zedek
Medical Center
Bone Infection; Joint
Infection
Invite
200
Clinical Study to Investigate the
Efficacy and the Safety of
Dexmedetomidine in Sedation
During the Surgery With Epidural
Anesthesia or Spinal Anesthesia
Without Intubation
study
NCT01438957
Pregabalin in the Prevention of
Postoperative Delirium and Pain
study
NCT00819988
Preoperative Thalidomide With
Radiation Therapy For Patients
With Low-Grade Primary Soft
Tissue Sarcoma or Thalidomide
With Radiation Therapy and
Chemotherapy For Patients With
High-Grade or Intermediate-Grade
Primary Soft Tissue Sarcoma of
the Arm, Leg, or Body Wall
Phase II
NCT00089544
Drug:
Dexmedetomidine
hydrochloride
Sedation
Rec
120
Adt Jun-10 Nov-11 Oxford
Sen
University
Hospitals NHS
Trust; Nuffield
Orthopaedic
Centre NHS
Trust
Adt Jun-11 Nov-11 Hospira, Inc.;
Sen
Maruishi
Pharmaceutical
Drug: Pregabalin;
Other: Sugar pill
Delirium; Pain
Comp
240
Adt May-09 Oct-11 Ottawa Hospital http://ClinicalTrials.gov/show/NCT00819988
Sen
Research
Institute; Pfizer
Comp
44
Child Jun-04 Sep-11 Radiation
Adt
Therapy
Sen
Oncology Group;
National Cancer
Institute (NCI)
Drug: dacarbazine;
Drug: doxorubicin
ifosfamide; Drug:
thalidomide;
Procedure: adjuvant
therapy; Procedure:
Procedure:
therapy
360
Supporting the Health of Adults
Drug: donepezil;
Delirium
Active, 40 Sen Jan-07 Aug-11 Beth Israel
Undergoing Orthopedic Surgery
Drug: Placebo
NR
Deaconess
During the Recovery Period
Medical Center;
Phase II: RCT, safety study
National Institute
NCT00586196
on Aging (NIA)
Safety and Efficacy of Repeated Drug: PMI-150
Pain, Postoperative Comp 250 Adt Jun-08 Aug-11 Hospira, Inc.
Doses of PMI-150 (Intranasal
(intranasal
Sen
Ketamine) in Acute Post-operative ketamine); Drug:
Pain Following Orthopedic Surgery Placebo
study
NCT00709436
Combination Chemotherapy, PEG- Biological: PEGSarcoma
Rec 2300 Child Nov-05 Jun-11 Children's
Interferon Alfa-2b, and Surgery in interferon alfa-2b;
Adt
Oncology Group;
Drug: cisplatin; Drug:
National Cancer
Osteosarcoma
doxorubicin
Institute (NCI);
Phase III: RCT
University
NCT00134030
etoposide; Drug:
College London
ifosfamide; Drug:
Hospitals
methotrexate
Cognitive Effects of Inhalational
Drug: inhalation
Lumbar Spondylosis; Rec
200 Sen Nov-08 Jun-11 Duke University; http://ClinicalTrials.gov/show/NCT00788008
Versus Intravenous General
anesthesia with
Cervical
Department of
Anesthesia in the Elderly
isoflurane vs. TIVA Spondylosis; Hip
Veterans Affairs
RCT, pharmacodynamics study with propofol
NCT00788008
Osteoarthritis
Assessing the Role of “Statin”
Drug: simvastatin;
Perioperative
Rec
70
Adt Apr-08 Jun-11 Mayo Clinic
Therapy and Perioperative
Drug: placebo
Inflammatory
Sen
Inflammatory Response in Patients
Response
Undergoing Major Orthopedic
Surgery"
NCT00656292
Chlorhexidine Versus Betadine in Drug: Skin antisepsis Infection
Not yet 200 Adt Oct-10 May-11 North Shore
Preventing Colonization of
with chlorhexidine;
Rec
Sen
Long Island
Femoral Nerve Catheters After
Drug: povidoneJewish Health
Total Joint Arthroplasty (TJA)
iodine
System
RCT, efficacy study
NCT00896402
361
An Observational Study On The
Drug: Fragmin®
Venous
Safety And Tolerability Of
(Dalteparin Sodium) Thromboembolism
Prolonged Thrombosis Prophylaxis
With Fragmin®
NCT01046903
Prospective randomised singleGenta-Coll resorb® Acute and chronic
blind trial for application of
osteomyelitis
GENTA-COLL resorb® for
treatment of acute and chronic
osteomyelitis
RCT
ISRCTN74677374
Treatment of Patients Colonized Drug: Placebo; Drug: Orthopedic
With Methicillin-Resistant
Altabax (retapamulin) Procedures;
Staphylococcus Aureus Prior to
Bone and Joint Surgery
Staphylococcus
Aureus
NCT00903279
Trial of 6% HES130/0.4
Drug: 6%
Hypovolemia;
hydroxyethyl starch Hemorrhage
study
130/0.4; Drug: 6%
NCT01010022
hydroxyethyl starch
70/0.5 (Salinhes®)
The Effect of Combined Ephedrine Drug: Ephedrine
Pain Due to Propofol
and Lidocaine Pretreatment on
30microgram/kg;
Injection;
Pain and Hemodynamic Changes Drug:
Hemodynamic
Due to Propofol Injection
lidocaine0.5mg/kg - Changes Due to
Phase I/II: RCT, safety/efficacy ephedrine30
Propofol Injection
study
micrograms/kg;
NCT01186549
Drug: ephedrine 70
microgram/kg; Drug:
lidocaine 0.5mg/kg;
Drug: normal saline
2ml
Comp
503
Wtdrwn 320
Adt Mar-10 Feb-11 Pfizer
Sen
Adt Feb-08 Feb-11 Friedrich Schiller http://www.controlledSen
University Jena trials.com/ISRCTN74677374
(Germany)
Wdrwn 400 Child Aug-09 Dec-10 Bay Pines VA
Adt
Healthcare
Sen
System
Comp
64
Adt Nov-09 Nov-10 Fresenius Kabi
Sen
Japan
Comp
165
Adt Aug-10 Nov-10 Qazvin
University Of
Medical
Sciences
362
Sorafenib and Ifosfamide in
Drug: sorafenib;
Treating Patients With High-Grade Drug: Ifosfamide
Soft Tissue Sarcoma or Bone
Sarcoma That Can Be Removed
by Surgery
study
NCT00880542
The cerebrospinal fluid (CSF)
Dyloject® (75 mg)
pharmacokinetics of a single pre- single intravenous
operative intravenous bolus dose bolus; Voltarol®
of diclofenac (Dyloject®) in
ampoules (75 mg)
comparison to diclofenac infusion single intravenous
(Voltarol®)
infusion
Phase IV: RCT
ISRCTN37500282
Ultrasound Guided Supraclavicular Drug: Ropivacaine;
Nerve Block
Drug: Mepivacaine
and ropivacaine
study
NCT00825786
Inhaled Sargramostim in Treating Biological:
Patients With First Pulmonary
sargramostim;
(Lung) Recurrence of
Procedure:
Osteosarcoma
conventional surgery
Phase II
NCT00066365
Prolotherapy Versus Steroids for Drug: Prolotherapy
Thumb Carpo-metacarpal Joint
(10% dextrose
Arthritis
solution); Drug:
Corticosteroid
NCT00685880
solution
Sarcoma
Term
7
Adt Aug-08 Nov-10 University of
Sen
California, Los
Angeles;
National Cancer
Institute (NCI)
Undergo surgery
performed under
spinal anaesthesia
Comp
20
Adt Feb-09 Aug-10 Barts and The
London NHS
Trust (UK)
Local Anesthetic;
upper extremity
procedures
Comp
120
Adt Sep-08 Aug-10 Outcomes
Sen
Research
Consortium
Metastatic Cancer;
Sarcoma
Comp
40
Child Jul-04
Adt
Thumb
Carpometacarpal
Joint Osteoarthritis
Term
2
Adt May-08 Jul-10 Mayo Clinic
Sen
363
Jul-10 Children's
Oncology Group;
National Cancer
Institute (NCI)
Comp
Drug: dacarbazine;
Drug: doxorubicin
ifosfamide; Drug:
mesna; Procedure:
Radiation:
brachytherapy;
Radiation:
intraoperative
radiation therapy;
Radiation:
radioisotope therapy
Study of Daptomycin in Subjects Drug: daptomycin;
Osteomyelitis
Comp
Undergoing Surgery for
Drug: daptomycin;
Osteomyelitis Associated With an Drug: vancomycin;
Infected Prosthetic Caused by
Drug: teicoplanin;
Staphylococci
Drug: nafcillin; Drug:
oxacillin; Drug:
study
flucloxacillin
NCT00428844
Ifosfamide and Doxorubicin,
Drug: doxorubicin
Childhood Malignant Rec
Radiation Therapy, and/or Surgery hydrochloride; Drug: Fibrous Histiocytoma
in Treating Young Patients With
ifosfamide;
of Bone; Sarcoma
Localized Soft Tissue Sarcoma
Procedure: adjuvant
Phase III: Non-Randomized;
therapy; Procedure:
NCT00334854
Procedure:
therapy
Adt Feb-97 Jun-10 Radiation
Sen
Therapy
Oncology Group;
National Cancer
Institute (NCI);
Eastern
Cooperative
Oncology Group
Chemotherapy Plus Radiation
Therapy Followed by Surgery in
Treating Patients With Soft Tissue
Sarcoma
Phase II
NCT00002791
75
Adt Jan-07 Jun-10 Cubist
Sen
Pharmaceuticals
250 Child Mar-06 May-10 European
Adt
Paediatric Soft
Tissue Sarcoma
Study Group;
Italian
Association for
Pediatric
Hematology
Oncology;
Cooperative
Weichteilsarkom
Studie;
Children's
Cancer and
Leukaemia
Group; Dutch
Childhood
Oncology Group
364
To compare dose and
concentration of local anaesthetics
in regional anaesthesia
RCT
ISRCTN44947124
To compare analgesia and side
effects of intrathecal fentanyl and
intrathecal morphine
RCT, efficacy study
ISRCTN49793641
Onset Time of Thiopental Versus
Propofol in the Elderly
NCT00965107
20ml
levobupivacaine
02.5% + 20ml
lidocaine 1% for
each block; 20ml
levobupivacaine
02.5% + 20ml
lidocaine 1% for
femoral block AND
10ml
levobupivacaine
0.5% + 10ml
lidocaine 2% for
sciatic block.
2.5ml heavy
bupivacaine 0.5% +
25mcg fentanyl
intrathecally; 2.5ml
heavy bupivacaine
0.5% + 50 mcg
morphine
intrathecally; 2.5ml
heavy bupivacaine
0.5% + 100mcg
morphine
intrathecally.
Drug: Thiopental;
Drug: Propofol
surgery
Comp
40
Adt May-09 Apr-10 North Wales
surgery
Comp
90
Adt May-09 Apr-10 North Wales
Induction of
Anaesthesia; Age
Comp
78
Adt Sep-09 Mar-10 Rigshospitalet,
Sen
Denmark;
TrygFonden,
Denmark
365
Biological:
Sarcoma
Active,
dactinomycin; Drug:
NR
cyclophosphamide;
Drug: doxorubicin
etoposide; Drug:
ifosfamide; Drug:
mesna; Drug:
vincristine sulfate;
Procedure:
Radiation: low-LET
cobalt-60 gamma ray
therapy; Radiation:
low-LET photon
therapy
Intravenous Ferric Carboxymaltose Drug: Ferinject ®
Iron Deficiency
Rec
(Ferinject®) With or Without
Anemia
Erythropoietin in Patients
Undergoing Orthopaedic Surgery
study
NCT00706667
Pharmacokinetic,
Drug: intravenous
Orthopaedic Surgery Rec
Pharmacodynamic and
morphine titration
Pharmacogenetic of Morphine
After Surgery
NCT00822549
Child Jul-92 Jan-10 Klinik und
Adt
Poliklinik fuer
Kinder und
Jugendmedizin Universitaetsklini
kum Muenster;
Medical
Research
Council
Combination Chemotherapy Plus
Surgery and Radiation Therapy in
Treating Patients With Ewing's
Sarcoma
Phase III
NCT00002516
Procedure
Chondrofix Osteochondral Allograft Procedure:
Prospective Study
Chondrofix
Osteochondral
Allograft
NCT01410136
Articular Cartilage
Disorder;
Degeneration;
Articular Cartilage;
Chronic Cartilage
Injury; Acute
Cartilage Injury;
Defect of Articular
Cartilage
Rec
75
Adt May-08 Jan-10 University of
Sen
Zurich; Vifor Inc.
500
Adt Sep-06 Jan-10 Assistance
Sen
Paris
50
Adt Apr-11 Sep-17 Zimmer
Sen
Orthobiologics,
Inc.
366
Prophylactic Antibiotic Regimens
in Tumor Surgery (PARITY): Pilot
Study
NCT01479283
Optimizing Catheter Insertion
Technique for Ultrasound-guided
Blocks
RCT, efficacy study
NCT01459523
Procedure:
Prophylactic
Cefazolin Antibiotic
Regimen
Infection; Bone
Neoplasms
Procedure: Proximal Pain, Postoperative
placement;
Procedure: Short
axis ultrasound;
Procedure: Long
axis; Procedure:
Distal placement
Safety and Efficacy of Cryoablation Procedure:
Pain; Neoplasm
Combined With Radiation Therapy Cryoablation;
Metastasis
for the Palliation of Painful Bone Procedure: Radiation
Metastases
study
NCT01461252
Safety and Efficacy of Cryoablation Procedure:
Pain; Neoplasm
for the Palliation of Painful Bone Cryoablation
Metastasis
Metastases
study
NCT01461265
Supported Fast track multi-Trauma Fast track multiMulti-trauma
Rehabilitation Service
trauma rehabilitation
Non-randomized efficacy study service;
ISRCTN68246661
Conventional multitrauma care service
Can the Usage of Regional Block Procedure: regional Anesthesia; Time
Room Save the Time of
anesthesia
Anesthesia Team
NCT01499589
Not yet 100 Child Jul-12 Jun-14 Michelle Ghert
Rec
Adt
Sen
Rec
200
Adt Oct-11 Oct-13 VA Palo Alto
Sen
Health Care
System
Not yet
Rec
40
Adt Feb-12 Sep-13 Galil Medical
Sen
Rec
40
Adt Nov-11 Jun-13 Galil Medical
Sen
Active
164
Adt Oct-08 Dec-12 Adelante
Sen
Rehabilitation
Centre (The
Netherlands)
Rec
800 Child Oct-11 Jul-12 Mahidol
Adt
University
Sen
367
Postoperative Nausea/Vomiting
and Acupressure
Phase II: Non-randomised,
parallel assignment, efficacy
study
NCT01389570
Procedure:
Acupressure wrist
band
PET Scan Combined With CT
Scan in Evaluating Treatment
Response in Patients Undergoing
Treatment for Bone Cancer or Soft
Tissue Sarcoma
NCT00335751
Procedure:
Sarcoma
computed
tomography;
Procedure: positron
emission
tomography;
Procedure:
radionuclide imaging;
Radiation:
fludeoxyglucose F 18
Radiotherapy with
Extremity soft tissue
Clinical Target
sarcoma
Volume (CTV) giving
5 cm margin; CTV
volume giving a 1.5
cm margin
longitudinally and 2
cm laterally
Procedure:
Osteoarticular
Infections; including
Microbiological
prosthetic joint
cultures and
infection
Molecular biology
Procedure:
Bone Tumors
Navigation surgery;
Procedure:
Navigation system
Randomised trial of volume of
post-operative radiotherapy given
to adult patients with extremity soft
tissue sarcoma
RCT
ISRCTN76456502
Postoperative
Nausea
Not yet 2000 Child Sep-11 Jun-12 National
Rec
Adt
Research Centre
Sen
of
Complementary
and Alternative
Medicine,
Norway;
Lovisenberg
Diakonale
Hospital
Comp 120 Adt Jan-06 Oct-11 University of
Sen
California, Los
Angeles;
National Cancer
Institute (NCI)
Comp
Molecular Microbiology in OsteoRec
arthritis Infection
NCT01193803
Navigation Surgery for Bone and
Rec
Soft Tissue Tumor
study
NCT01179698
Procedure: Standard Draining Hematoma Active,
Treatment for Draining
Pressure Dressing;
NR
Hematomas
Device: VAC
RCT, efficacy study
NCT00582179
400 Child Jan-06 Jul-11 University of
Adt
Sheffield (UK)
Sen
284
Adt Oct-08 Apr-11 Assistance
Sen
Paris
Child Jan-09 Dec-10 Samsung
Adt
Medical Center
Sen
Sen
Alabama at
Birmingham
45
94
368
Pre and Post Arthrogram
Ultrasound Images of Joints
NCT00724659
HLA Sensitization Following Major
Cortical Allograft Bone Procedures
NCT00160719
Treatment Outcome After Surgical
Treatment of Osteoid Osteoma
NCT01466010
Other
Observation Versus Post-surgery
Radiotherapy After Complete
Exeresis in Soft Tissues Members
Sarcoma
NCT00870701
Improving a Bayesian Model's
Survival Estimates in Patients
Needing Surgery for Bone
Metastases
NCT01470105
Patient Anxiety and Concern as
Predictors for the Perceived
Quality and Efficacy of Treatment
NCT01205295
Procedure:
Ultrasound;
Procedure:
Ultrasound
Procedure: retrieve
blood samples
Arthrography
Active,
NR
300
Sen
Michigan
Bone Cancer
Comp
120 Child Sep-99 Mar-10 University of
Adt
Florida
Sen
Procedure: surgical
removal of osteoid
osteoma
Osteoid Osteoma
Comp
150 Child Jan-98 Jan-10 Universitaire
Adt
Ziekenhuizen
Sen
Leuven
Radiation:
Soft Tissue Sarcoma
Radiotherapy; Other: of Members
absence of
radiotherapy
Rec
570
Adt Mar-09 Mar-21 Institut Claudius http://ClinicalTrials.gov/show/NCT00870701
Sen
Regaud
Other: blood
Bone Metastases
sampling, the SF-36
questionnaire
Rec
440
Adt Nov-11 Nov-14 Memorial Sloan- http://ClinicalTrials.gov/show/NCT01470105
Sen
Kettering Cancer
Center; Naval
Medical
Research Center
Other: Cognitive
Anxiety; Orthopedic
behavioural therapy Surgery
Rec
800
Not yet
Rec
10
Adt Sep-10 Feb-13 Kolding
Sen
Sygehus;
Odense
University
Hospital;
University of
Southern
Denmark
Adt Jan-12 Jan-13 Tel-Aviv
Sen
Sourasky
Medical Center
Restrictive Versus Liberal Red Cell Other: Red blood
Transfusion Strategy in
cells transfusion
Orthopedic-Oncology Patients
Undergoing Surgery - a
Randomized Controlled Study
RCT
NCT01491308
Red Blood Cells
Transfusion.
369
Remote Orthopedic Outpatient
Consultation by Help of
Telemedicine
NCT00616837
Pain and Function After
Orthopedic Surgery
NCT01390298
A Migration and Bone Density
Study Comparing 2 Types of Bone
Cement in the OptiPac Bone
Cement Mixing System
NCT00678236
Dynamic Contrast Enhanced
MRI(DCE-MRI)of Bone Tumors
efficacy study
NCT00598741
Other: Telemedicine Orthopedic
consultation
Conditions
Rec
400 Child Nov-07 Dec-12 University
Adt
Hospital of North
Sen
Norway; Helse
Nord
Other: Observational Chronic Pain
Rec
75
Adt
Sen
Sen Jun-08 Sep-12 University of
Aarhus; Aarhus
University
Hospital; Biomet,
Inc.
Jul-11 Nov-12 Wake Forest
University
Other: Refobacin
Bone Cement R;
Other: Refobacin
Plus Bone Cement
Osteoarthritis
Active,
NR
54
Other: DCE-MRI
Sarcoma; Bone
Tumor
Active,
NR
210 Child Jul-04
Adt
Sen
Tissue Sample Collection From
Genetic: microarray Sarcoma
Patients With Soft Tissue Sarcoma analysis; Genetic:
of the Arms, Hands, Legs, or Feet molecular diagnostic
Treated on Clinial Trial CRUKmethod; Other:
VORTEX
biologic sample
NCT00900211
preservation
procedure
Orthopaedic Patient Recognition of Other: Orthopaedic Patient Satisfaction
Attending Improves Satisfaction
Attending Biosketch
Evaluations (Orthopaedic PRAISE Card
Study)
RCT
NCT01263639
Rec
Jul-12 Memorial Sloan- http://ClinicalTrials.gov/show/NCT00598741
Kettering Cancer
Center; New
York
Presbyterian
Hospital;
University of
Oregon;
University
College, London;
Montefiore
Hospital
400 Child Aug-07 Mar-12 Christie Hospital http://ClinicalTrials.gov/show/NCT00900211
Adt
NHS Foundation
Sen
Trust
Not yet 200
Rec
370
Adt Jan-11 Feb-12 Vanderbilt
Sen
University
Detection of Circulating
Other: Blood draw
Osteosarcoma
Osteosarcoma Tumor Cells in the
Blood of Patients Using the
Polymerase Chain Reaction
NCT00588510
Amputee Residual Limb Volume Other: Monitored for Amputation
Fluctuation
limb volume
NCT01161238
Traditional Chinese Medicine in
Routine care of Orthopaedic
Rehabilitation - sustainability and
acceptance by patients of the
German Pension Fund
RCT
ISRCTN40932605
Comp
Rec
Usual care; usual
Chronic back pain
Comp
care + TCM
and/or osteoarthritis
(acupuncture, tuina- of one or more joints
massage, herbal
therapy, qi gong or
tai chi and
consultations to way
of life and dietetics)
Establishment of Optimal
Other: Allowed drop Anemia;
Comp
Transfusion Threshold After Major in hemoglobin to 4.5- Arthroplasty;
Orthopedic Surgery
5.5 mmol/L; Other: Replacement; Hip
RCT, efficacy study
Allowed drop in
NCT00906295
hemoglobin to level
between 5.6-6.5
mmol/L
Two Strategies for MethicillinOther: Rapid
MRSA Infection
Active,
resistant Staphylococcus Aureus molecular MRSA
NR
(MRSA) Infection Prevention in
test; Behavioral:
Surgical Patients
Hand hygiene
promotion
assignment
NCT00685867
59
Child Jan-00 Sep-11 Memorial Sloan- http://ClinicalTrials.gov/show/NCT00588510
Adt
Kettering Cancer
Sen
Center
100 Child May-10 Sep-11 University of
Adt
Washington;
Sen
Eunice Kennedy
Shriver National
Institute of Child
Health and
Human
Development
520 Adt Jan-09 Jun-11 Refonet
(Germany)
67
Adt Jun-09 Jun-11 Rigshospitalet,
Sen
Denmark;
TrygFonden,
Denmark
30
Child May-08 Dec-10 University
Adt
Hospital,
Sen
Geneva
371
Intensity-Modulated Radiation
Therapy in Treating Patients
Undergoing Surgery for Stage IB,
Stage II, or Stage III Soft Tissue
Sarcoma
Phase II
NCT00740597
Effect of Systematic Medication
Review in Elderly Patients
Admitted to an Orthopedic
Department
RCT, safety study
NCT00738816
Genetic: gene
Sarcoma
expression analysis;
Genetic: polymerase
chain reaction;
Genetic: western
blotting; Procedure:
Procedure:
therapeutic
Radiation: intensitymodulated radiation
therapy
Other: Systematic
Elderly
medication review
and advisory notes
Retrieval and Analysis of
Orthopedic Implants at Revision
NCT01425021
Clinical Orthopaedic Data Bank
(Acute and Chronic)
Prospective study
NCT00411060
Huntsman Biopsy Study
NCT00615329
Identification of Risk Factors of
Prolonged Wound Healing
Following Primary Arthroplasty
NCT01477047
Term
30
Adt
Sen
Comp
108
Adt Apr-09 Apr-10 Aarhus
Sen
University
Hospital
Total Joint Revisions Invite
500
Sen
Utah
Osteoarthritis;
Osteosarcoma;
Scoliosis; Cerebral
Palsy
Soft Tissue
Sarcoma;
Osteosarcoma
1000 Child Jan-07 Jan-20 University of
0
Adt
Florida
Sen
Evaluate Surgical,
Medical and
Pharmacological
Factors Influence on
Wound Healing
Following Primary
Rec
Rec
Jul-08 Apr-10 City of Hope
Medical Center;
National Cancer
Institute (NCI)
100 Child Apr-03 Dec-15 State University http://ClinicalTrials.gov/show/NCT00615329
Adt
of New York Sen
Upstate Medical
University;
Huntsman
Cancer Institute
Not yet 3000 Adt Jan-12 Jan-14 Hvidovre
Rec
Sen
University
Hospital
372
Pro Osteon Bone Void Filler Study
NCT00858598
Thromboembolic Events After
Elective Orthopaedic Surgery in
Patients Treated With PRADAXA
NCT01139658
Effect of Spinal Cord Stimulation
on Pain Thresholds and Sensory
Perception in Chronic Pain
Patients
study
NCT01137617
Objective Functional Outcome
Measures in Orthopedic Surgery
Using Advanced Tracking
Technologies
NCT00641823
OrthoIllustrated Web Based
Orthopaedic Sports Medicine
Registry
NCT01191151
Musculotendinous Tissue Repair
Unit and Reinforcement (MTURR)
NCT01292876
Musculotendinous Tissue Unit
Repair and Reinforcement
(MTURR) Coordinating Center
NCT01497678
Osteoarthritis;
Revision
Arthroplasty
Venous
Thromboembolism
Wdrwn
Rec
0
Adt Dec-09 Jan-14 Biomet, Inc.
Sen
1660 Adt Aug-10 Jul-12 Boehringer
Sen
Ingelheim
Pharmaceuticals
Chronic Pain
Rec
60
Adt Jun-10 Jun-12 Massachusetts http://ClinicalTrials.gov/show/NCT01137617
Sen
General Hospital
Orthopedic
Disorders
Rec
60
Adt Mar-08 Mar-12 Hadassah
Sen
Medical
Organization
Degenerative and
Rec 12500 Child Sep-10 Mar-12 Arthrex, Inc.
Traumatic Pathology
Adt
of the Knee;
Sen
Degenerative and
Traumatic Pathology
of the Shoulder;
Degenerative and
Traumatic Pathology
of the Foot and
Ankle
Traumatic Injury;
Rec
40
Muscle Injury;
Pittsburgh
Tendon Injury; Soft
Tissue Injury;
Extremity Injury
Traumatic Injury;
Not yet 40
Adt Feb-12 Dec-11 University of
Muscle Injury;
Rec
Pittsburgh;
Tendon Injury; Soft
United States
Tissue Injury;
Naval Medical
Extremity Injury
Center,
Portsmouth
373
Inflammatory Cytokine Variations
in Traumatic Injury Responses
NCT00593892
Inflammatory
Active,
Cytokine Variations
NR
Following Traumatic
Injury
150
A Comparison of Ultrasound and
Nerve Stimulator Techniques for
Nerve Localization in Regional
Anesthesia
Prospective study
NCT01221415
Ultrasound Confirmation of
Fluoroscopically Guided Piriformis
Muscle Injections
NCT01390090
The Incidence of TRALI in Patients
Undergoing Orthopedic-Oncology
Surgery
NCT00914784
Rapid Identification of Key
Pathogens in Wound Infection by
Molecular Means
NCT00287599
Perfusion Index (PI) and Pleth
Variability Index (PVI) in Patients
With Interscalene Blocks in
Orthopedic Surgery
NCT01389011
Transfusion-Associated
Microchimerism in Previously
Injured Individuals Who Received
a Blood Transfusion
NCT00441779
Orthopedic
Comp
220
Rec
60
Sen
Alabama at
Birmingham;
Orthopaedic
Trauma
Association
Adt Jan-08 Oct-11 Ochsner Health http://ClinicalTrials.gov/show/NCT01221415
Sen
System
Sen
Florida
Dyspnea; Pulmonary Not yet 550
Edema
Rec
Adt Aug-09 Sep-11 Tel-Aviv
Sen
Sourasky
Medical Center
Postoperative
Wound Infection;
Traumatic Wound
Infection; Closed
Soft Tissue Abscess
Perfusion Index and
Pleth Variability
Index; Interscalene
Blocks; Orthopedic
Surgery
Comp
400
Adt Oct-06 Aug-11 Brentwood
Sen
Biomedical
Research
Institute
Comp
30
Adt Sep-10 Jul-11 Johannes
Sen
Gutenberg
University Mainz
Chimerism; Blood
Transfusion;
Wounds and
Injuries; Traumatic
injuries; Burn
injuries; Elective
orthopedic
operations.
Invite
600 Child Aug-08 Jun-11 National Heart, http://ClinicalTrials.gov/show/NCT00441779
Adt
Lung, and Blood
Sen
Institute (NHLBI)
Subjects Will Have
Failed Conservative
Treatment.
374
Collection of Blood, Bone Marrow,
Leukapheresis, and Tissue Biopsy
Samples From Patients and Their
Family Members for Center for
Human Immunology,
Autoimmunity, and Inflammatory
Diseases Laboratory Research
Studies
NCT01200823
MRI Study of Musculoskeletal
Function
NCT00051857
Idopathic
Inflammatory;
Autoimmune
Syndromes
Rec
N/K Child Jun-10 Jun-11 National Heart, http://ClinicalTrials.gov/show/NCT01200823
Adt
Lung, and Blood
Sen
Institute (NHLBI)
Healthy
Rec
Comparison of Three Methods of
Hemoglobin Monitoring
NCT00792597
Cytogenetic and Molecular Genetic
Studies in Bone Sarcomas
NCT00579930
Standard Deviation of the Distance
Between the Sural Nerve and
Achilles Tendon by Ultrasound
NCT01112605
Evaluation of the Surgical Pleth
Index During Spinal and General
Anesthesia
NCT00789438
Blood Loss
Comp
500 Child Jan-03 Apr-11 National
Adt
Institutes of
Sen
Health Clinical
Center (CC)
20
Adt Apr-09 Dec-10 University of
Sen
California, San
Francisco
Lung Cancer
Susp
0
Healthy
Comp
50
Adt
Apr-10 May-10 Meir Medical
Center
Stress; Pain
Comp
69
Adt Oct-08 May-10 University of
Sen
SchleswigHolstein
375
Child Dec-93 Dec-10 Memorial Sloan- http://ClinicalTrials.gov/show/NCT00579930
Adt
Kettering Cancer
Sen
Center

1 HORIZON SCANNING:ORTHOPAEDIC

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