Scientific Program

Organized by:
Network Italiano per la Bioterapia dei tumori (NIBIT)
Under the auspices of the Italian Society for Immunology, Clinical Immunology and Allergy
(SIICA)
Sponsors:
Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany
Moffit Cancer Center, Tampa, FL, USA
Biolegend Italia / Campoverde Srl, Milano, Italy,
Dr T.F. Yu Foundation, New York, NY, USA
Society of Chinese Bioscientists in America (SCBA), Houston, TX, USA
Medimmune, Gaithersburg, MD, USA
European Federation of Immunological Societes
Meeting Secretariat: Ms. Rita Repizzi [email protected]
Website: http://nibit.org/convegni.php
ORGANIZING COMMITEE
SCIENTIFIC COMMITTEE
Co-chairs:
Co-Chairs :
Vito Pistoia
Michele Maio
Phillip Beckove
Giorgio Trinchieri
Members:
Members:
Phillip Beckove,
Mario Colombo,
Paola Pistoia,
Giorgio Trinchieri,
Simonetta Trinchieri,
Viktor Umansky.
Mario Colombo
Julie Djeu
Manlio Ferrarini
Michele Maio
Alberto Mantovani
Giorgio Parmiani
Vito Pistoia
Robert Wiltrout
Viktor Umansky
Hua Yu.
Wednesday September 16 th , 8:15-12:30 AM
Session 1: Inflammation and Cancer
Chairs: Phillip Bechove and Giorgio Trinchieri
8:15-8:30
Opening
8:30-9:00
Alberto Mantovani (Humanitas, Milano, Italy): Role of innate
resistance and complement in cancer
9:00-9:30
Hua Yu (City of Hope, CA, USA): Stat3 in cancer
9:30-10:00
Hellmut Augustin (DKFZ, Germany): Therapeutic targeting of
inflammation and angiogenesis in the metastatic niche
10:00-10:30 Coffee break
10:30-11:00 Mathias Heikenwälder (DKFZ, Germany): Inflammation-driven
hepatocellular carcinogenesis
11:00-11:30 Yinling Hu (NCI, USA): Ikkα in carcinogenesis
11:30-12:00 David Wink (NCI, USA): The Legacy of Nitric Oxide: Impact on
Cancer Biology
12:00-12:30 Veffa Franchini (NCI, USA): RAS activation in protective vaccines
against HIV
12:30
Lunch, Santa Caterina Cloisters
Wednesday September 16 th , 1:30-7:00 PM
1:30-2:15
Biolegend special presentation: Dr Carsten Wiethe: "Advanced
multicolor flow cytometry for enhanced immunophenotyping approaches in
inflammation and immunity"
Session 2: Tumor microenvironment and associated
inflammatory cells
Chairs: Vito Pistoia and Romina Goldszmid
2:30-3:00
Miriam Merad (Mt. Sinai, New York, USA): Functional heterogeneity
of the tumor-associated myeloid compartment
3:00-3:30
Shu-Hsia Chen (Mt Sinai, New York, USA ): Reprogram of myeloid
suppressive functions
3:30-4:00
Niels Grabe (DKFZ, Germany): Imaging Immune responses against
human cancer
4:00-4:30
Viktor Umansky (DKFZ): Immune regulatory circuits in melanoma
4:30-5:00
Coffee break
5:00-5:30
Günter Hämmerling (DKFZ, Germany): Eosinophils and tumor
immune rejection
5:30-6:00
Li Yang (NCI, USA): TGF-β signaling in myeloid cells is required for
tumor metastasis.
6:00-6:30
Dan McVicar (NCI, USA): Regulation of Myeloid Cell Metabolism by
IL-10 and Nitric Oxide
6:30-7:00
Mario P. Colombo (Istituto Tumori, Milano, Italy): Immune and
cancerous activities of matricellular proteins
Thursday September 17 th , 8:15 AM – 1:00 PM
Session 3: Microbiota and cancer
Chairs: Viktor Humansky and Dan McVicar
8:15-8:30
Opening
8:30-9:00
Yasmine Belkaid (NIAID, USA): Microbiota and immunity
9:00-9:30
Fiona Powrie (Oxford U.): Microbiota, mucosal immunity, and cancer
9:30-10:00
Christian Jobin (U. Florida, USA): Microbiota and colorectal cancer:
Moving from genomic studies to drug targets
10:00-10:30 Romina Goldszmid (NCI, USA): Microbiota regulation of myeloid
cells in cancer
10:30-11:00 Coffee break
11:00-11:30 Luca Vannucci (Prague, Czech Republic): Microbiota and stroma in
colon carcinogenesis
Session 4: Immune response to tumors
Chairs: Gunther Hämmerling and Nick Restifo
11:30-12:00 Matt Gubin (Wash. U., St Louis, MS): Immune recognition
12:00-12:30 Mary Carrington (NCI): HLA genetics in infections and cancer
12:30-1:00
Donna Farber (Columbia U., New York, USA): Tissue
compartmentalization of human T cells
1:00 PM
Lunch, Santa Caterina Cloisters
Thursday September 17th, Afternoon and Evening
Afternoon: Poster presentations, Visit to the Borgo and Castles
8:00-10:30 PM Social Dinner, Santa Caterina Cloisters
Friday September 18th, 8:15-12:30 AM
Session 4 (continued): Immune response to tumors
Chairs: Gunther Hämmerling and Nick Restifo
8:15-8:30
Opening
8:30-9:00
Jay Berzofsky (NCI, USA): Cancer Vaccine
9:00-9:30
Luca Gattinoni (NCI, USA): Tumor specific memory T cells
9:30-10:00
Lorenzo Moretta (Bambino Gesù Hospital in Rome, Italy): Innate
immunity to tumors
10:00-10:30 Coffee break
10:30-11:00 Adelheid Cerwenka (DKFZ Germany): NK cells and anticancer
immunity
11:00-11:30 Julie Djeu (Moffitt Cancer C., FL, USA): Regulation of Tumor
Associated NK cells
11:30-12:00 Philipp Beckhove (DKFZ, Germany): Radioimmunotherapy
12:00-12:30 Michael Platten (DKFZ, Germany): Mutation specific vaccines
12:30 Lunch, Santa Caterina Cloisters
Friday September 18 th, 2:15-6:00 PM
Session 5: Cancer Immunology and Immunotherapy
Chairs: Giorgio Parmiani and Julie Djeu
2:15-2:30
Giorgio Parmiani (San Raffaele, Milano, and Ist. Toscano Tumori,
Siena, Italy): Introductory remarks
2:30-3:00
Nick Restifo (NCI, USA): Adoptive T cell transfer
3:00-3:30
Manlio Ferrarini (Istituto San Martino, Genova Italy): CLL: a disease
caused by gene deregulation and BcR stimulation
3:30-4:00
Coffee break
4:00-4:30
Attilio Bondanza (San Raffaele, Milano, Italy): Immunotherapy of
hematologic malignancies
4:30-5:00
Ignacio Melero (U. Navarra, Pamplona, Spain): Mechanisms
underlying-cell costimulation and coinhibition for cancer
immunotherapy.
5:00-5:30
Michele Maio (Ist. Toscano Tumori, Siena, Italy): Evolving
Immunotherapeutic Options