honor roll of donors - UCSF Helen Diller Family Comprehensive
Transcription
honor roll of donors - UCSF Helen Diller Family Comprehensive
financial highlights Visionary Circle Honor Roll of Donors Lifetime Giving of $1 Million and Above Restricted $27,754,549 7.1% e.g., to a specific program Unrestricted $2,115,236 92.9% e.g., General Fund Total$29,869,785 1% Sources of Philanthropic Support To cancer programs at UCSF for the fiscal year ending June 30, 2013 Individuals $15,935,803 Foundations and Family Foundations Corporations 15% Other Organizations $9,198,295 53% 31% $4,559,126 $176,561 Total$29,869,785 Sources of Philanthropic Support $45,828,912 $42,437,012 $36,491,451 Yearly summary for fiscal years 2009–2013 $31,913,032 $29,869,785 Other Organizations Individuals Foundations and Family Foundations Corporations 2009 2010 2011 2012 2013 Anonymous (18) Accelerate Brain Cancer Cure, Inc. The Bonnie J. Addario Lung Cancer Foundation Estate of Edward S. Ageno American Association for Cancer Research American Brain Tumor Association American Cancer Society American Cancer Society California Division American Society of Clinical Oncology Estate of Stanford W. Ascherman The Atlantic Philanthropies Martha and H. Brewster Atwater Roma M. Auerback Avon Foundation Ayco Charitable Foundation Lynne and Marc R. Benioff Theodora B. Betz Foundation Bionovo, Inc. Jane Bishop * Frances F. Bowes William K. Bowes, Jr. Foundation The Breast Cancer Research Foundation Linda and Neill H. Brownstein Carol Franc Buck Eva Benson Buck Charitable Trust D Estate of Hildur V. Bullerwell Christine and Steven A. Burd Frank A. Campini Foundation Cancer Research Institute Champion Charities Chevron U.S.A. Inc. Estate of Ruth M. DeBernardi Donna M. and Kenneth T. Derr Helen Diller Family Foundation Ann H. and L. John Doerr III Estate of Volker Dolch Carol P. and Michael I. Dollinger The Dougherty Family Foundation Greg Dougherty Nancy Dougherty Joseph Drown Foundation The Ellison Medical Foundation Anne and Jason Farber Foundation, Inc. Estate of Condina J. Ferro Fidelity Investments Charitable Gift Fund Fisher Families Joseph H. Friend * Susan M. Geck * Genentech, Inc. The Goldhirsh Foundation, Inc. Richard and Rhoda Goldman Fund Richard N. Goldman * Nancy and Stephen Grand Guzik Foundation Mimi and Peter Haas Fund Estate of E. Dixon Heise Informed Medical Decisions Foundation Pepper and Michael Jackson Joan and Irwin M. Jacobs Jewish Community Federation of San Francisco, the Peninsula, Marin and Sonoma Counties Jewish Community Foundation Jewish Community Foundation of San Diego Kalmanovitz Charitable Foundation Kazan, McClain, Abrams, Fernandez, Lyons, Greenwood, Harley & Oberman Foundation Kirk Kerkorian Alison and Arthur H. Kern Gwen M. and John A. Kerner Sidney Kimmel Foundation for Cancer Research The Susan G. Komen Breast Cancer Foundation Deepa N. Iyengar and Ashok Krishnamurthi Mary V. Lester and W. Howard Lester * The Leukemia and Lymphoma Society The Lincy Foundation The Listwin Family Foundation Edmund & Jeannik Littlefield Foundation Jeannik Mequet Littlefield * Marin Community Foundation Lucille P. Markey Charitable Trust Estate of Alicia McEvoy Estate of Claire C. McEvoy Estate of Jay D. McEvoy Nan Tucker McEvoy Nion T. McEvoy The Minneapolis Foundation Estate of Frederick S. Moody Betty I. and Gordon E. Moore Mount Zion Health Fund Multiple Myeloma Research Foundation National Brain Tumor Society Merillyn J. Noren Susan and William E. Oberndorf The Bernard Osher Foundation Pediatric Brain Tumor Foundation Jeffrey and Karen Peterson Family Foundation Estate of Kathleen Mahoney Plant Catherine H. and Michael H. Podell Helen* and Sol* Price Prospect Creek Foundation Prostate Cancer Foundation Radiology Research and Education Foundation Estate of Mary Ann Radovich George R. Roberts Estate of Mario J. Rocca Arthur and Toni Rembe Rock Rombauer Family Damon Runyon Cancer Research Foundation The Safeway Foundation Safeway, Inc. The San Francisco Foundation San Francisco General Hospital Foundation Schwab Charitable Fund Bernard Lee Schwartz Foundation, Inc. Estate of Jack Douglas Shand William Siebrandt Silicon Valley Community Foundation Sandra Lloyd and W. Douglass Smith Elle and Paul H. Stephens Alexander and Margaret Stewart Trust The V Foundation for Cancer Research Eddi and Wendell Van Auken Vanguard Charitable Endowment Program Angela C. Wang Dana A. Corvin and Harris Weinberg Robert K. Werbe * Diana S. * and Herschel S. * Zackheim *deceased 2012–2013 Address service requested To cancer programs at UCSF for the fiscal year ending June 30, 2013 0906 University Development and Alumni Relations UCSF Box 0248 San Francisco, CA 94143-0248 Allocation of Philanthropic Support Possibilities for Partnership To learn more about our cancer center priorities, please contact: Suzanne Teer, Executive Director of Development 415/476-3622 [email protected] UCSF Box 0248, San Francisco, CA 94143-0248 support.ucsf.edu Produced by the UCSF Office of University Development and Alumni Relations Managing Editor: Kate Volkman Oakes Design: Pamela Kato Writers: Jason Bardi, Elizabeth Fernandez, Susan Godstone, Photographers: Steve Babuljak, Noah Berger, Cindy Chew, Samantha Jang, Kate Volkman Oakes Elisabeth Fall, Susan Godstone, Carmen Holt © 2013 The Regents of the University of California We’ve Gone Green! Please visit us online to view a complete list of FY12-13 donors: support.ucsf.edu/cancer/honor-roll Year in Review your gifts, our thanks Top Accomplishments SUPPORTING BREAST CANCER RESEARCH Genetic Answers to Lymphedema Dear Friends, UCSF researchers have found an association between certain genes and the development of lymphedema, a painful condition that often occurs after breast cancer surgery and some other cancer treatments. “These genes are ‘turned on’ later in the development of our lymph system and blood vessels,” says Bradley Aouizerat, PhD, professor in the School of Nursing and co-leader of the study. “They appear to play a role in the ability of our lymphatic system to function on an ongoing basis. In some individuals who have changes in these genes it’s possible that lymphedema could develop after an injury like breast cancer surgery.” Lymphedema is the buildup of fluid in the lymphatic tissues and can be debilitating, causing scarring, discomfort, and difficulty in walking or other activities. Up to 56 percent of women who undergo breast cancer surgery develop lymphedema within two years. Researchers hope to identify women at risk for the condition and initiate measures to prevent its development. After 17 years as director of the UCSF Helen Diller Family Comprehensive Cancer Center, it’s time for me to focus full time on my research. I will pursue investigations both in my lab at UCSF and as director of a new National Cancer Institute (NCI)-funded project in Frederick, Maryland. As I prepare to pass the torch to my yet-to-be-named successor, I can’t help but reflect on my many rewarding experiences as director. I came to UC San Francisco in 1996 to lead the Cancer Research Institute and quickly set up shop to consolidate UCSF’s various cancer programs into a comprehensive cancer center. In 1998 we received our first NCI cancer center support grant and became, for the first time, an NCI-designated comprehensive cancer center. My first act as head of the new center was to recruit an additional batch of brilliant minds in basic research, clinical research, and population sciences. Together we elevated the quality of investigations, and developed robust clinical trials and informatics programs. Fifteen years later we are one of the top cancer centers in the country, as well as the largest and best funded center in California. Simultaneous to building up all these outstanding cancer programs, we built the UCSF Helen Diller Family Cancer Research Building. The facility has been a boon to our work. Our scientists are thriving among the powerhouse research community at Mission Bay, and our clinicians look forward to the opening of the new cancer hospital a couple blocks away. But one of my most gratifying experiences has been getting to know you, our donors who believe in our mission. I’d especially like to thank the Diller family for your extraordinary legacy of support. I also offer heartfelt thanks to Cathy Podell and Nanci Fredkin – the organizers of our fundraising gala, Raising Hope, which began in 1996 – and to The Atlantic Philanthropies for your loyalty to our center. And I extend my deep gratitude to Barbara and Gerson Bakar. I am delighted that the new cancer hospital at Mission Bay will be named the UCSF Bakar Cancer Hospital in honor of your longstanding commitment to cancer research and care. I sign off with a special thanks to all of you for your constant support and for continuing to push the boundaries of our imagination. As the new director takes the reins, I trust that your loyalty will remain steadfast. Changing the Standard of Care UCSF clinicians who ran a Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, say the results may change the standard of care for the disease. Patients received a combination of highdose chemotherapy with immune therapy, rather than the standard combination of chemotherapy with whole-brain radiotherapy. The new approach was less toxic and worked better, with the majority of patients still alive five years following treatment. The lymphoma-free survival of patients with this form of cancer was doubled compared to the lymphoma-free survival in previous trials involving brain radiotherapy, says UCSF oncologist James Rubenstein, MD, PhD, who led the study. He and his team also found a gene that, depending on how much of it is present, is a biomarker for potentially predicting treatment outcomes – a discovery that may enable personalized care. Harold Varmus and J. Michael Bishop win the Nobel Prize for their discovery of cancer-causing oncogenes Nancy White Gamble’s life changed in 2008, when she was diagnosed with acute promyelocytic leukemia, a rare form of blood cancer. Within days, Gamble, who lives in Napa, Calif., met with UCSF’s Lloyd Damon, MD, director of hematologic malignancies and bone marrow transplant. Although the treatment that followed was harrowing, Gamble survived. In remission five years later, she attributes much of her survival not only to the excellent care she received at UCSF, but also to the hope Damon instilled in her. “He threw me a life preserver,” Gamble recalls, “and all I had to do was grab it.” To show her gratitude, Gamble made a pledge to create the Nancy White Gamble Hematologic-Malignancies Endowment. The endowment will support an annual fellowship for future Bone Marrow Transplantation (BMT) physicians. Training the next generation is critical, says Damon, who holds the Robert O. and Angela W. Johnson Endowed Chair of Hematopoetic Malignancies. While the need for BMT continues to grow, the number of doctors entering the field has not. The endowment will provide much-needed funding to help reverse this trend. Researchers have discovered that melanoma cells that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf) also develop addiction to the drug – an observation with potential implications for patients with late-stage disease. The team, based at UCSF, the Novartis Institutes for Biomedical Research in Emeryville, Calif., and University Hospital Zurich, found that as a result of their addiction, cells use vemurafenib to spur the growth of rapidly progressing, deadly, and drug-resistant tumors. However, adjusting the dosing and introducing an on-again, off-again treatment schedule prolonged the life of mice with melanoma, says co-lead researcher Martin McMahon, PhD, the Efim Guzik Distinguished Professor of Cancer Biology. A similar approach may extend the effectiveness of the drug for people – an idea that awaits testing in clinical trials. Melanoma is the most aggressive type of skin cancer. In 2012 alone, an estimated 76,250 people in the US were newly diagnosed with it, while 9,180 people died from the disease. Director, UCSF Helen Diller Family Comprehensive Cancer Center E. Dixon Heise Distinguished Professor in Oncology David A. Wood Distinguished Professor of Tumor Biology and Cancer Research Cancer Center Milestones Blood Cancer LifeLine Flows Both Ways Lloyd Damon with Nancy White Gamble Interrupting Treatment Prolongs Life Frank McCormick, PhD, FRS, DSc (Hon) 1989 Mark Moasser (left) with Sisi and Bert Damner Diagnosed with breast cancer in 2010, Sisi Damner interviewed many physicians before she found Mark M. Moasser, MD, a breast care specialist at the UCSF Carol Franc Buck Breast Care Center. “He’s an authority in his field and he’s also a good listener,” Damner says. “The two don’t always go together.” Moasser is one of several UCSF physician-scientists working at the interface of the clinical and scientific realms. He credits the patients he cares for in the oncology clinic for motivating his research. “Our larger vision is to find curative therapies for cancers driven by the HER2/neu oncogene, which account for 20 to 25 percent of breast cancers as well as many other cancers,” he says. Three years later, Damner is busy traveling and taking up new hobbies. In gratitude, she and her husband, Bert, named the UCSF breast cancer program a beneficiary of their charitable remainder trust. “We can’t help but want to support UCSF’s research into breast cancer,” Damner says, “the findings from which have the potential to make a difference to cancer patients and their families worldwide.” 1998 First became an NCI-designated comprehensive cancer center, an honor maintained through today 2007 Cancer Center renamed the UCSF Helen Diller Family Comprehensive Cancer Center in tribute to the family’s commitment to improving lives around the world Partnering to fight brain cancer Ashley Dabbiere is mother to four active young children, so when she noticed a creeping forgetfulness she attributed it to “baby brain.” But a 2012 MRI revealed a tumor occupying more than half of her brain’s frontal lobe. “My husband and I immediately started doing research because we wanted to find the best brain surgeon in the world. We quickly settled on Dr. Berger,” says Ashley, who lives outside Washington, DC. Mitchel Berger, MD, is the Berthold and Belle N. Guggenhime Professor and director of the Brain Tumor Research Center at UCSF. “The Dabbieres took ownership of the problem in a way that they could be part of the solution,” says Berger. The couple made two unrestricted gifts toward Berger’s research, which he is using to investigate how low grade slow-growing gliomas (the type Ashley has) evolve into high grade fast-growing tumors. “We can’t do what Dr. Berger does,” says Alan. “What we can do is build awareness and provide funding to help him find better cures for my wife and a lot of people. We are glad to partner with UCSF.” Mitch Berger (left) with Ashley and Alan Dabbiere 2009 Helen Diller Family Cancer Research Building opens at Mission Bay, bringing investigators into the center of a powerful basic research community 2013 Elizabeth Blackburn wins the Nobel Prize for her codiscovery of telomeres and the enzyme telomerase, which have implications for cancer therapies U.S. News & World Report ranked UCSF Medical Center as the 7th best hospital in the nation, 1st among California, and among the top in the nation for the 8th consecutive year 2015 UCSF Bakar Cancer Hospital at Mission Bay slated to open to patients Year in Review your gifts, our thanks Top Accomplishments SUPPORTING BREAST CANCER RESEARCH Genetic Answers to Lymphedema Dear Friends, UCSF researchers have found an association between certain genes and the development of lymphedema, a painful condition that often occurs after breast cancer surgery and some other cancer treatments. “These genes are ‘turned on’ later in the development of our lymph system and blood vessels,” says Bradley Aouizerat, PhD, professor in the School of Nursing and co-leader of the study. “They appear to play a role in the ability of our lymphatic system to function on an ongoing basis. In some individuals who have changes in these genes it’s possible that lymphedema could develop after an injury like breast cancer surgery.” Lymphedema is the buildup of fluid in the lymphatic tissues and can be debilitating, causing scarring, discomfort, and difficulty in walking or other activities. Up to 56 percent of women who undergo breast cancer surgery develop lymphedema within two years. Researchers hope to identify women at risk for the condition and initiate measures to prevent its development. After 17 years as director of the UCSF Helen Diller Family Comprehensive Cancer Center, it’s time for me to focus full time on my research. I will pursue investigations both in my lab at UCSF and as director of a new National Cancer Institute (NCI)-funded project in Frederick, Maryland. As I prepare to pass the torch to my yet-to-be-named successor, I can’t help but reflect on my many rewarding experiences as director. I came to UC San Francisco in 1996 to lead the Cancer Research Institute and quickly set up shop to consolidate UCSF’s various cancer programs into a comprehensive cancer center. In 1998 we received our first NCI cancer center support grant and became, for the first time, an NCI-designated comprehensive cancer center. My first act as head of the new center was to recruit an additional batch of brilliant minds in basic research, clinical research, and population sciences. Together we elevated the quality of investigations, and developed robust clinical trials and informatics programs. Fifteen years later we are one of the top cancer centers in the country, as well as the largest and best funded center in California. Simultaneous to building up all these outstanding cancer programs, we built the UCSF Helen Diller Family Cancer Research Building. The facility has been a boon to our work. Our scientists are thriving among the powerhouse research community at Mission Bay, and our clinicians look forward to the opening of the new cancer hospital a couple blocks away. But one of my most gratifying experiences has been getting to know you, our donors who believe in our mission. I’d especially like to thank the Diller family for your extraordinary legacy of support. I also offer heartfelt thanks to Cathy Podell and Nanci Fredkin – the organizers of our fundraising gala, Raising Hope, which began in 1996 – and to The Atlantic Philanthropies for your loyalty to our center. And I extend my deep gratitude to Barbara and Gerson Bakar. I am delighted that the new cancer hospital at Mission Bay will be named the UCSF Bakar Cancer Hospital in honor of your longstanding commitment to cancer research and care. I sign off with a special thanks to all of you for your constant support and for continuing to push the boundaries of our imagination. As the new director takes the reins, I trust that your loyalty will remain steadfast. Changing the Standard of Care UCSF clinicians who ran a Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, say the results may change the standard of care for the disease. Patients received a combination of highdose chemotherapy with immune therapy, rather than the standard combination of chemotherapy with whole-brain radiotherapy. The new approach was less toxic and worked better, with the majority of patients still alive five years following treatment. The lymphoma-free survival of patients with this form of cancer was doubled compared to the lymphoma-free survival in previous trials involving brain radiotherapy, says UCSF oncologist James Rubenstein, MD, PhD, who led the study. He and his team also found a gene that, depending on how much of it is present, is a biomarker for potentially predicting treatment outcomes – a discovery that may enable personalized care. Harold Varmus and J. Michael Bishop win the Nobel Prize for their discovery of cancer-causing oncogenes Nancy White Gamble’s life changed in 2008, when she was diagnosed with acute promyelocytic leukemia, a rare form of blood cancer. Within days, Gamble, who lives in Napa, Calif., met with UCSF’s Lloyd Damon, MD, director of hematologic malignancies and bone marrow transplant. Although the treatment that followed was harrowing, Gamble survived. In remission five years later, she attributes much of her survival not only to the excellent care she received at UCSF, but also to the hope Damon instilled in her. “He threw me a life preserver,” Gamble recalls, “and all I had to do was grab it.” To show her gratitude, Gamble made a pledge to create the Nancy White Gamble Hematologic-Malignancies Endowment. The endowment will support an annual fellowship for future Bone Marrow Transplantation (BMT) physicians. Training the next generation is critical, says Damon, who holds the Robert O. and Angela W. Johnson Endowed Chair of Hematopoetic Malignancies. While the need for BMT continues to grow, the number of doctors entering the field has not. The endowment will provide much-needed funding to help reverse this trend. Researchers have discovered that melanoma cells that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf) also develop addiction to the drug – an observation with potential implications for patients with late-stage disease. The team, based at UCSF, the Novartis Institutes for Biomedical Research in Emeryville, Calif., and University Hospital Zurich, found that as a result of their addiction, cells use vemurafenib to spur the growth of rapidly progressing, deadly, and drug-resistant tumors. However, adjusting the dosing and introducing an on-again, off-again treatment schedule prolonged the life of mice with melanoma, says co-lead researcher Martin McMahon, PhD, the Efim Guzik Distinguished Professor of Cancer Biology. A similar approach may extend the effectiveness of the drug for people – an idea that awaits testing in clinical trials. Melanoma is the most aggressive type of skin cancer. In 2012 alone, an estimated 76,250 people in the US were newly diagnosed with it, while 9,180 people died from the disease. Director, UCSF Helen Diller Family Comprehensive Cancer Center E. Dixon Heise Distinguished Professor in Oncology David A. Wood Distinguished Professor of Tumor Biology and Cancer Research Cancer Center Milestones Blood Cancer LifeLine Flows Both Ways Lloyd Damon with Nancy White Gamble Interrupting Treatment Prolongs Life Frank McCormick, PhD, FRS, DSc (Hon) 1989 Mark Moasser (left) with Sisi and Bert Damner Diagnosed with breast cancer in 2010, Sisi Damner interviewed many physicians before she found Mark M. Moasser, MD, a breast care specialist at the UCSF Carol Franc Buck Breast Care Center. “He’s an authority in his field and he’s also a good listener,” Damner says. “The two don’t always go together.” Moasser is one of several UCSF physician-scientists working at the interface of the clinical and scientific realms. He credits the patients he cares for in the oncology clinic for motivating his research. “Our larger vision is to find curative therapies for cancers driven by the HER2/neu oncogene, which account for 20 to 25 percent of breast cancers as well as many other cancers,” he says. Three years later, Damner is busy traveling and taking up new hobbies. In gratitude, she and her husband, Bert, named the UCSF breast cancer program a beneficiary of their charitable remainder trust. “We can’t help but want to support UCSF’s research into breast cancer,” Damner says, “the findings from which have the potential to make a difference to cancer patients and their families worldwide.” 1998 First became an NCI-designated comprehensive cancer center, an honor maintained through today 2007 Cancer Center renamed the UCSF Helen Diller Family Comprehensive Cancer Center in tribute to the family’s commitment to improving lives around the world Partnering to fight brain cancer Ashley Dabbiere is mother to four active young children, so when she noticed a creeping forgetfulness she attributed it to “baby brain.” But a 2012 MRI revealed a tumor occupying more than half of her brain’s frontal lobe. “My husband and I immediately started doing research because we wanted to find the best brain surgeon in the world. We quickly settled on Dr. Berger,” says Ashley, who lives outside Washington, DC. Mitchel Berger, MD, is the Berthold and Belle N. Guggenhime Professor and director of the Brain Tumor Research Center at UCSF. “The Dabbieres took ownership of the problem in a way that they could be part of the solution,” says Berger. The couple made two unrestricted gifts toward Berger’s research, which he is using to investigate how low grade slow-growing gliomas (the type Ashley has) evolve into high grade fast-growing tumors. “We can’t do what Dr. Berger does,” says Alan. “What we can do is build awareness and provide funding to help him find better cures for my wife and a lot of people. We are glad to partner with UCSF.” Mitch Berger (left) with Ashley and Alan Dabbiere 2009 Helen Diller Family Cancer Research Building opens at Mission Bay, bringing investigators into the center of a powerful basic research community 2013 Elizabeth Blackburn wins the Nobel Prize for her codiscovery of telomeres and the enzyme telomerase, which have implications for cancer therapies U.S. News & World Report ranked UCSF Medical Center as the 7th best hospital in the nation, 1st among California, and among the top in the nation for the 8th consecutive year 2015 UCSF Bakar Cancer Hospital at Mission Bay slated to open to patients Year in Review your gifts, our thanks Top Accomplishments SUPPORTING BREAST CANCER RESEARCH Genetic Answers to Lymphedema Dear Friends, UCSF researchers have found an association between certain genes and the development of lymphedema, a painful condition that often occurs after breast cancer surgery and some other cancer treatments. “These genes are ‘turned on’ later in the development of our lymph system and blood vessels,” says Bradley Aouizerat, PhD, professor in the School of Nursing and co-leader of the study. “They appear to play a role in the ability of our lymphatic system to function on an ongoing basis. In some individuals who have changes in these genes it’s possible that lymphedema could develop after an injury like breast cancer surgery.” Lymphedema is the buildup of fluid in the lymphatic tissues and can be debilitating, causing scarring, discomfort, and difficulty in walking or other activities. Up to 56 percent of women who undergo breast cancer surgery develop lymphedema within two years. Researchers hope to identify women at risk for the condition and initiate measures to prevent its development. After 17 years as director of the UCSF Helen Diller Family Comprehensive Cancer Center, it’s time for me to focus full time on my research. I will pursue investigations both in my lab at UCSF and as director of a new National Cancer Institute (NCI)-funded project in Frederick, Maryland. As I prepare to pass the torch to my yet-to-be-named successor, I can’t help but reflect on my many rewarding experiences as director. I came to UC San Francisco in 1996 to lead the Cancer Research Institute and quickly set up shop to consolidate UCSF’s various cancer programs into a comprehensive cancer center. In 1998 we received our first NCI cancer center support grant and became, for the first time, an NCI-designated comprehensive cancer center. My first act as head of the new center was to recruit an additional batch of brilliant minds in basic research, clinical research, and population sciences. Together we elevated the quality of investigations, and developed robust clinical trials and informatics programs. Fifteen years later we are one of the top cancer centers in the country, as well as the largest and best funded center in California. Simultaneous to building up all these outstanding cancer programs, we built the UCSF Helen Diller Family Cancer Research Building. The facility has been a boon to our work. Our scientists are thriving among the powerhouse research community at Mission Bay, and our clinicians look forward to the opening of the new cancer hospital a couple blocks away. But one of my most gratifying experiences has been getting to know you, our donors who believe in our mission. I’d especially like to thank the Diller family for your extraordinary legacy of support. I also offer heartfelt thanks to Cathy Podell and Nanci Fredkin – the organizers of our fundraising gala, Raising Hope, which began in 1996 – and to The Atlantic Philanthropies for your loyalty to our center. And I extend my deep gratitude to Barbara and Gerson Bakar. I am delighted that the new cancer hospital at Mission Bay will be named the UCSF Bakar Cancer Hospital in honor of your longstanding commitment to cancer research and care. I sign off with a special thanks to all of you for your constant support and for continuing to push the boundaries of our imagination. As the new director takes the reins, I trust that your loyalty will remain steadfast. Changing the Standard of Care UCSF clinicians who ran a Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, say the results may change the standard of care for the disease. Patients received a combination of highdose chemotherapy with immune therapy, rather than the standard combination of chemotherapy with whole-brain radiotherapy. The new approach was less toxic and worked better, with the majority of patients still alive five years following treatment. The lymphoma-free survival of patients with this form of cancer was doubled compared to the lymphoma-free survival in previous trials involving brain radiotherapy, says UCSF oncologist James Rubenstein, MD, PhD, who led the study. He and his team also found a gene that, depending on how much of it is present, is a biomarker for potentially predicting treatment outcomes – a discovery that may enable personalized care. Harold Varmus and J. Michael Bishop win the Nobel Prize for their discovery of cancer-causing oncogenes Nancy White Gamble’s life changed in 2008, when she was diagnosed with acute promyelocytic leukemia, a rare form of blood cancer. Within days, Gamble, who lives in Napa, Calif., met with UCSF’s Lloyd Damon, MD, director of hematologic malignancies and bone marrow transplant. Although the treatment that followed was harrowing, Gamble survived. In remission five years later, she attributes much of her survival not only to the excellent care she received at UCSF, but also to the hope Damon instilled in her. “He threw me a life preserver,” Gamble recalls, “and all I had to do was grab it.” To show her gratitude, Gamble made a pledge to create the Nancy White Gamble Hematologic-Malignancies Endowment. The endowment will support an annual fellowship for future Bone Marrow Transplantation (BMT) physicians. Training the next generation is critical, says Damon, who holds the Robert O. and Angela W. Johnson Endowed Chair of Hematopoetic Malignancies. While the need for BMT continues to grow, the number of doctors entering the field has not. The endowment will provide much-needed funding to help reverse this trend. Researchers have discovered that melanoma cells that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf) also develop addiction to the drug – an observation with potential implications for patients with late-stage disease. The team, based at UCSF, the Novartis Institutes for Biomedical Research in Emeryville, Calif., and University Hospital Zurich, found that as a result of their addiction, cells use vemurafenib to spur the growth of rapidly progressing, deadly, and drug-resistant tumors. However, adjusting the dosing and introducing an on-again, off-again treatment schedule prolonged the life of mice with melanoma, says co-lead researcher Martin McMahon, PhD, the Efim Guzik Distinguished Professor of Cancer Biology. A similar approach may extend the effectiveness of the drug for people – an idea that awaits testing in clinical trials. Melanoma is the most aggressive type of skin cancer. In 2012 alone, an estimated 76,250 people in the US were newly diagnosed with it, while 9,180 people died from the disease. Director, UCSF Helen Diller Family Comprehensive Cancer Center E. Dixon Heise Distinguished Professor in Oncology David A. Wood Distinguished Professor of Tumor Biology and Cancer Research Cancer Center Milestones Blood Cancer LifeLine Flows Both Ways Lloyd Damon with Nancy White Gamble Interrupting Treatment Prolongs Life Frank McCormick, PhD, FRS, DSc (Hon) 1989 Mark Moasser (left) with Sisi and Bert Damner Diagnosed with breast cancer in 2010, Sisi Damner interviewed many physicians before she found Mark M. Moasser, MD, a breast care specialist at the UCSF Carol Franc Buck Breast Care Center. “He’s an authority in his field and he’s also a good listener,” Damner says. “The two don’t always go together.” Moasser is one of several UCSF physician-scientists working at the interface of the clinical and scientific realms. He credits the patients he cares for in the oncology clinic for motivating his research. “Our larger vision is to find curative therapies for cancers driven by the HER2/neu oncogene, which account for 20 to 25 percent of breast cancers as well as many other cancers,” he says. Three years later, Damner is busy traveling and taking up new hobbies. In gratitude, she and her husband, Bert, named the UCSF breast cancer program a beneficiary of their charitable remainder trust. “We can’t help but want to support UCSF’s research into breast cancer,” Damner says, “the findings from which have the potential to make a difference to cancer patients and their families worldwide.” 1998 First became an NCI-designated comprehensive cancer center, an honor maintained through today 2007 Cancer Center renamed the UCSF Helen Diller Family Comprehensive Cancer Center in tribute to the family’s commitment to improving lives around the world Partnering to fight brain cancer Ashley Dabbiere is mother to four active young children, so when she noticed a creeping forgetfulness she attributed it to “baby brain.” But a 2012 MRI revealed a tumor occupying more than half of her brain’s frontal lobe. “My husband and I immediately started doing research because we wanted to find the best brain surgeon in the world. We quickly settled on Dr. Berger,” says Ashley, who lives outside Washington, DC. Mitchel Berger, MD, is the Berthold and Belle N. Guggenhime Professor and director of the Brain Tumor Research Center at UCSF. “The Dabbieres took ownership of the problem in a way that they could be part of the solution,” says Berger. The couple made two unrestricted gifts toward Berger’s research, which he is using to investigate how low grade slow-growing gliomas (the type Ashley has) evolve into high grade fast-growing tumors. “We can’t do what Dr. Berger does,” says Alan. “What we can do is build awareness and provide funding to help him find better cures for my wife and a lot of people. We are glad to partner with UCSF.” Mitch Berger (left) with Ashley and Alan Dabbiere 2009 Helen Diller Family Cancer Research Building opens at Mission Bay, bringing investigators into the center of a powerful basic research community 2013 Elizabeth Blackburn wins the Nobel Prize for her codiscovery of telomeres and the enzyme telomerase, which have implications for cancer therapies U.S. News & World Report ranked UCSF Medical Center as the 7th best hospital in the nation, 1st among California, and among the top in the nation for the 8th consecutive year 2015 UCSF Bakar Cancer Hospital at Mission Bay slated to open to patients financial highlights Visionary Circle Honor Roll of Donors Lifetime Giving of $1 Million and Above Restricted $27,754,549 7.1% e.g., to a specific program Unrestricted $2,115,236 92.9% e.g., General Fund Total$29,869,785 1% Sources of Philanthropic Support To cancer programs at UCSF for the fiscal year ending June 30, 2013 Individuals $15,935,803 Foundations and Family Foundations Corporations 15% Other Organizations $9,198,295 53% 31% $4,559,126 $176,561 Total$29,869,785 Sources of Philanthropic Support $45,828,912 $42,437,012 $36,491,451 Yearly summary for fiscal years 2009–2013 $31,913,032 $29,869,785 Other Organizations Individuals Foundations and Family Foundations Corporations 2009 2010 2011 2012 2013 Anonymous (18) Accelerate Brain Cancer Cure, Inc. The Bonnie J. Addario Lung Cancer Foundation Estate of Edward S. Ageno American Association for Cancer Research American Brain Tumor Association American Cancer Society American Cancer Society California Division American Society of Clinical Oncology Estate of Stanford W. Ascherman The Atlantic Philanthropies Martha and H. Brewster Atwater Roma M. Auerback Avon Foundation Ayco Charitable Foundation Lynne and Marc R. Benioff Theodora B. Betz Foundation Bionovo, Inc. Jane Bishop * Frances F. Bowes William K. Bowes, Jr. Foundation The Breast Cancer Research Foundation Linda and Neill H. Brownstein Carol Franc Buck Eva Benson Buck Charitable Trust D Estate of Hildur V. Bullerwell Christine and Steven A. Burd Frank A. Campini Foundation Cancer Research Institute Champion Charities Chevron U.S.A. Inc. Estate of Ruth M. DeBernardi Donna M. and Kenneth T. Derr Helen Diller Family Foundation Ann H. and L. John Doerr III Estate of Volker Dolch Carol P. and Michael I. Dollinger The Dougherty Family Foundation Greg Dougherty Nancy Dougherty Joseph Drown Foundation The Ellison Medical Foundation Anne and Jason Farber Foundation, Inc. Estate of Condina J. Ferro Fidelity Investments Charitable Gift Fund Fisher Families Joseph H. Friend * Susan M. Geck * Genentech, Inc. The Goldhirsh Foundation, Inc. Richard and Rhoda Goldman Fund Richard N. Goldman * Nancy and Stephen Grand Guzik Foundation Mimi and Peter Haas Fund Estate of E. Dixon Heise Informed Medical Decisions Foundation Pepper and Michael Jackson Joan and Irwin M. Jacobs Jewish Community Federation of San Francisco, the Peninsula, Marin and Sonoma Counties Jewish Community Foundation Jewish Community Foundation of San Diego Kalmanovitz Charitable Foundation Kazan, McClain, Abrams, Fernandez, Lyons, Greenwood, Harley & Oberman Foundation Kirk Kerkorian Alison and Arthur H. Kern Gwen M. and John A. Kerner Sidney Kimmel Foundation for Cancer Research The Susan G. Komen Breast Cancer Foundation Deepa N. Iyengar and Ashok Krishnamurthi Mary V. Lester and W. Howard Lester * The Leukemia and Lymphoma Society The Lincy Foundation The Listwin Family Foundation Edmund & Jeannik Littlefield Foundation Jeannik Mequet Littlefield * Marin Community Foundation Lucille P. Markey Charitable Trust Estate of Alicia McEvoy Estate of Claire C. McEvoy Estate of Jay D. McEvoy Nan Tucker McEvoy Nion T. McEvoy The Minneapolis Foundation Estate of Frederick S. Moody Betty I. and Gordon E. Moore Mount Zion Health Fund Multiple Myeloma Research Foundation National Brain Tumor Society Merillyn J. Noren Susan and William E. Oberndorf The Bernard Osher Foundation Pediatric Brain Tumor Foundation Jeffrey and Karen Peterson Family Foundation Estate of Kathleen Mahoney Plant Catherine H. and Michael H. Podell Helen* and Sol* Price Prospect Creek Foundation Prostate Cancer Foundation Radiology Research and Education Foundation Estate of Mary Ann Radovich George R. Roberts Estate of Mario J. Rocca Arthur and Toni Rembe Rock Rombauer Family Damon Runyon Cancer Research Foundation The Safeway Foundation Safeway, Inc. The San Francisco Foundation San Francisco General Hospital Foundation Schwab Charitable Fund Bernard Lee Schwartz Foundation, Inc. Estate of Jack Douglas Shand William Siebrandt Silicon Valley Community Foundation Sandra Lloyd and W. Douglass Smith Elle and Paul H. Stephens Alexander and Margaret Stewart Trust The V Foundation for Cancer Research Eddi and Wendell Van Auken Vanguard Charitable Endowment Program Angela C. Wang Dana A. Corvin and Harris Weinberg Robert K. Werbe * Diana S. * and Herschel S. * Zackheim *deceased 2012–2013 Address service requested To cancer programs at UCSF for the fiscal year ending June 30, 2013 0906 University Development and Alumni Relations UCSF Box 0248 San Francisco, CA 94143-0248 Allocation of Philanthropic Support Possibilities for Partnership To learn more about our cancer center priorities, please contact: Suzanne Teer, Executive Director of Development 415/476-3622 [email protected] UCSF Box 0248, San Francisco, CA 94143-0248 support.ucsf.edu Produced by the UCSF Office of University Development and Alumni Relations Managing Editor: Kate Volkman Oakes Design: Pamela Kato Writers: Jason Bardi, Elizabeth Fernandez, Susan Godstone, Photographers: Steve Babuljak, Noah Berger, Cindy Chew, Samantha Jang, Kate Volkman Oakes Elisabeth Fall, Susan Godstone, Carmen Holt © 2013 The Regents of the University of California We’ve Gone Green! Please visit us online to view a complete list of FY12-13 donors: support.ucsf.edu/cancer/honor-roll financial highlights Visionary Circle Honor Roll of Donors Lifetime Giving of $1 Million and Above Restricted $27,754,549 7.1% e.g., to a specific program Unrestricted $2,115,236 92.9% e.g., General Fund Total$29,869,785 1% Sources of Philanthropic Support To cancer programs at UCSF for the fiscal year ending June 30, 2013 Individuals $15,935,803 Foundations and Family Foundations Corporations 15% Other Organizations $9,198,295 53% 31% $4,559,126 $176,561 Total$29,869,785 Sources of Philanthropic Support $45,828,912 $42,437,012 $36,491,451 Yearly summary for fiscal years 2009–2013 $31,913,032 $29,869,785 Other Organizations Individuals Foundations and Family Foundations Corporations 2009 2010 2011 2012 2013 Anonymous (18) Accelerate Brain Cancer Cure, Inc. The Bonnie J. Addario Lung Cancer Foundation Estate of Edward S. Ageno American Association for Cancer Research American Brain Tumor Association American Cancer Society American Cancer Society California Division American Society of Clinical Oncology Estate of Stanford W. Ascherman The Atlantic Philanthropies Martha and H. Brewster Atwater Roma M. Auerback Avon Foundation Ayco Charitable Foundation Lynne and Marc R. Benioff Theodora B. Betz Foundation Bionovo, Inc. Jane Bishop * Frances F. Bowes William K. Bowes, Jr. Foundation The Breast Cancer Research Foundation Linda and Neill H. Brownstein Carol Franc Buck Eva Benson Buck Charitable Trust D Estate of Hildur V. Bullerwell Christine and Steven A. Burd Frank A. Campini Foundation Cancer Research Institute Champion Charities Chevron U.S.A. Inc. Estate of Ruth M. DeBernardi Donna M. and Kenneth T. Derr Helen Diller Family Foundation Ann H. and L. John Doerr III Estate of Volker Dolch Carol P. and Michael I. Dollinger The Dougherty Family Foundation Greg Dougherty Nancy Dougherty Joseph Drown Foundation The Ellison Medical Foundation Anne and Jason Farber Foundation, Inc. Estate of Condina J. Ferro Fidelity Investments Charitable Gift Fund Fisher Families Joseph H. Friend * Susan M. Geck * Genentech, Inc. The Goldhirsh Foundation, Inc. Richard and Rhoda Goldman Fund Richard N. Goldman * Nancy and Stephen Grand Guzik Foundation Mimi and Peter Haas Fund Estate of E. Dixon Heise Informed Medical Decisions Foundation Pepper and Michael Jackson Joan and Irwin M. Jacobs Jewish Community Federation of San Francisco, the Peninsula, Marin and Sonoma Counties Jewish Community Foundation Jewish Community Foundation of San Diego Kalmanovitz Charitable Foundation Kazan, McClain, Abrams, Fernandez, Lyons, Greenwood, Harley & Oberman Foundation Kirk Kerkorian Alison and Arthur H. Kern Gwen M. and John A. Kerner Sidney Kimmel Foundation for Cancer Research The Susan G. Komen Breast Cancer Foundation Deepa N. Iyengar and Ashok Krishnamurthi Mary V. Lester and W. Howard Lester * The Leukemia and Lymphoma Society The Lincy Foundation The Listwin Family Foundation Edmund & Jeannik Littlefield Foundation Jeannik Mequet Littlefield * Marin Community Foundation Lucille P. Markey Charitable Trust Estate of Alicia McEvoy Estate of Claire C. McEvoy Estate of Jay D. McEvoy Nan Tucker McEvoy Nion T. McEvoy The Minneapolis Foundation Estate of Frederick S. Moody Betty I. and Gordon E. Moore Mount Zion Health Fund Multiple Myeloma Research Foundation National Brain Tumor Society Merillyn J. Noren Susan and William E. Oberndorf The Bernard Osher Foundation Pediatric Brain Tumor Foundation Jeffrey and Karen Peterson Family Foundation Estate of Kathleen Mahoney Plant Catherine H. and Michael H. Podell Helen* and Sol* Price Prospect Creek Foundation Prostate Cancer Foundation Radiology Research and Education Foundation Estate of Mary Ann Radovich George R. Roberts Estate of Mario J. Rocca Arthur and Toni Rembe Rock Rombauer Family Damon Runyon Cancer Research Foundation The Safeway Foundation Safeway, Inc. The San Francisco Foundation San Francisco General Hospital Foundation Schwab Charitable Fund Bernard Lee Schwartz Foundation, Inc. Estate of Jack Douglas Shand William Siebrandt Silicon Valley Community Foundation Sandra Lloyd and W. Douglass Smith Elle and Paul H. Stephens Alexander and Margaret Stewart Trust The V Foundation for Cancer Research Eddi and Wendell Van Auken Vanguard Charitable Endowment Program Angela C. Wang Dana A. Corvin and Harris Weinberg Robert K. Werbe * Diana S. * and Herschel S. * Zackheim *deceased 2012–2013 Address service requested To cancer programs at UCSF for the fiscal year ending June 30, 2013 0906 University Development and Alumni Relations UCSF Box 0248 San Francisco, CA 94143-0248 Allocation of Philanthropic Support Possibilities for Partnership To learn more about our cancer center priorities, please contact: Suzanne Teer, Executive Director of Development 415/476-3622 [email protected] UCSF Box 0248, San Francisco, CA 94143-0248 support.ucsf.edu Produced by the UCSF Office of University Development and Alumni Relations Managing Editor: Kate Volkman Oakes Design: Pamela Kato Writers: Jason Bardi, Elizabeth Fernandez, Susan Godstone, Photographers: Steve Babuljak, Noah Berger, Cindy Chew, Samantha Jang, Kate Volkman Oakes Elisabeth Fall, Susan Godstone, Carmen Holt © 2013 The Regents of the University of California We’ve Gone Green! Please visit us online to view a complete list of FY12-13 donors: support.ucsf.edu/cancer/honor-roll financial highlights Visionary Circle Honor Roll of Donors Lifetime Giving of $1 Million and Above Restricted $27,754,549 7.1% e.g., to a specific program Unrestricted $2,115,236 92.9% e.g., General Fund Total$29,869,785 1% Sources of Philanthropic Support To cancer programs at UCSF for the fiscal year ending June 30, 2013 Individuals $15,935,803 Foundations and Family Foundations Corporations 15% Other Organizations $9,198,295 53% 31% $4,559,126 $176,561 Total$29,869,785 Sources of Philanthropic Support $45,828,912 $42,437,012 $36,491,451 Yearly summary for fiscal years 2009–2013 $31,913,032 $29,869,785 Other Organizations Individuals Foundations and Family Foundations Corporations 2009 2010 2011 2012 2013 Anonymous (18) Accelerate Brain Cancer Cure, Inc. The Bonnie J. Addario Lung Cancer Foundation Estate of Edward S. Ageno American Association for Cancer Research American Brain Tumor Association American Cancer Society American Cancer Society California Division American Society of Clinical Oncology Estate of Stanford W. Ascherman The Atlantic Philanthropies Martha and H. Brewster Atwater Roma M. Auerback Avon Foundation Ayco Charitable Foundation Lynne and Marc R. Benioff Theodora B. Betz Foundation Bionovo, Inc. Jane Bishop * Frances F. Bowes William K. Bowes, Jr. Foundation The Breast Cancer Research Foundation Linda and Neill H. Brownstein Carol Franc Buck Eva Benson Buck Charitable Trust D Estate of Hildur V. Bullerwell Christine and Steven A. Burd Frank A. Campini Foundation Cancer Research Institute Champion Charities Chevron U.S.A. Inc. Estate of Ruth M. DeBernardi Donna M. and Kenneth T. Derr Helen Diller Family Foundation Ann H. and L. John Doerr III Estate of Volker Dolch Carol P. and Michael I. Dollinger The Dougherty Family Foundation Greg Dougherty Nancy Dougherty Joseph Drown Foundation The Ellison Medical Foundation Anne and Jason Farber Foundation, Inc. Estate of Condina J. Ferro Fidelity Investments Charitable Gift Fund Fisher Families Joseph H. Friend * Susan M. Geck * Genentech, Inc. The Goldhirsh Foundation, Inc. Richard and Rhoda Goldman Fund Richard N. Goldman * Nancy and Stephen Grand Guzik Foundation Mimi and Peter Haas Fund Estate of E. Dixon Heise Informed Medical Decisions Foundation Pepper and Michael Jackson Joan and Irwin M. Jacobs Jewish Community Federation of San Francisco, the Peninsula, Marin and Sonoma Counties Jewish Community Foundation Jewish Community Foundation of San Diego Kalmanovitz Charitable Foundation Kazan, McClain, Abrams, Fernandez, Lyons, Greenwood, Harley & Oberman Foundation Kirk Kerkorian Alison and Arthur H. Kern Gwen M. and John A. Kerner Sidney Kimmel Foundation for Cancer Research The Susan G. Komen Breast Cancer Foundation Deepa N. Iyengar and Ashok Krishnamurthi Mary V. Lester and W. Howard Lester * The Leukemia and Lymphoma Society The Lincy Foundation The Listwin Family Foundation Edmund & Jeannik Littlefield Foundation Jeannik Mequet Littlefield * Marin Community Foundation Lucille P. Markey Charitable Trust Estate of Alicia McEvoy Estate of Claire C. McEvoy Estate of Jay D. McEvoy Nan Tucker McEvoy Nion T. McEvoy The Minneapolis Foundation Estate of Frederick S. Moody Betty I. and Gordon E. Moore Mount Zion Health Fund Multiple Myeloma Research Foundation National Brain Tumor Society Merillyn J. Noren Susan and William E. Oberndorf The Bernard Osher Foundation Pediatric Brain Tumor Foundation Jeffrey and Karen Peterson Family Foundation Estate of Kathleen Mahoney Plant Catherine H. and Michael H. Podell Helen* and Sol* Price Prospect Creek Foundation Prostate Cancer Foundation Radiology Research and Education Foundation Estate of Mary Ann Radovich George R. Roberts Estate of Mario J. Rocca Arthur and Toni Rembe Rock Rombauer Family Damon Runyon Cancer Research Foundation The Safeway Foundation Safeway, Inc. The San Francisco Foundation San Francisco General Hospital Foundation Schwab Charitable Fund Bernard Lee Schwartz Foundation, Inc. Estate of Jack Douglas Shand William Siebrandt Silicon Valley Community Foundation Sandra Lloyd and W. Douglass Smith Elle and Paul H. Stephens Alexander and Margaret Stewart Trust The V Foundation for Cancer Research Eddi and Wendell Van Auken Vanguard Charitable Endowment Program Angela C. Wang Dana A. Corvin and Harris Weinberg Robert K. Werbe * Diana S. * and Herschel S. * Zackheim *deceased 2012–2013 Address service requested To cancer programs at UCSF for the fiscal year ending June 30, 2013 0906 University Development and Alumni Relations UCSF Box 0248 San Francisco, CA 94143-0248 Allocation of Philanthropic Support Possibilities for Partnership To learn more about our cancer center priorities, please contact: Suzanne Teer, Executive Director of Development 415/476-3622 [email protected] UCSF Box 0248, San Francisco, CA 94143-0248 support.ucsf.edu Produced by the UCSF Office of University Development and Alumni Relations Managing Editor: Kate Volkman Oakes Design: Pamela Kato Writers: Jason Bardi, Elizabeth Fernandez, Susan Godstone, Photographers: Steve Babuljak, Noah Berger, Cindy Chew, Samantha Jang, Kate Volkman Oakes Elisabeth Fall, Susan Godstone, Carmen Holt © 2013 The Regents of the University of California We’ve Gone Green! Please visit us online to view a complete list of FY12-13 donors: support.ucsf.edu/cancer/honor-roll