MAR `2013 - Seattle South Asian
Transcription
MAR `2013 - Seattle South Asian
SEATTLESouthAsian Monthly Community Paper | [email protected] | 206-501-2254 | Vol. 4 No. 3 Immigration Reform HOLI By Ramey Ko The potential for comprehensive immigration reform during President Obama’s second term increased dramatically on January 28 and 29, after a bipartisan group of US Senators and the President both announced proposals for reform. Many immigrant advocates are particularly hopeful because of the similarity between the two proposals, at least at first glance, and the President’s statement on Tuesday that he will wait and see how the Senate plan develops before deciding whether to submit his own bill to Congress. With a divided (Continued On Page 09) The festival of Holi is celebrated because of a story in the old Hindu religion. In Vaishnavism, Hiranyakashipu is the great king of demons, and he had been granted a boon by Brahma, which made it almost impossible for him to be killed. The boon was due to his long penance, after which he had demanded that he not be killed “during day or night; inside the home or outside, not on earth or in the sky; neither by a man nor an animal; neither by astra nor by shastra”. Conseq u e n t l y, he grew arrogant and attacked the Heavens and the Earth. (Continued On Page 15) EASTER You Can Advertise In SEATTLE SOUTH ASIAN for Just $29 Month Easter (Old English: Ēostre) or the Pasch or (among Eastern Orthodox) Pascha (Latin: Pascha; Greek: Πάσχα, Paskha; Aramaic: Pasa; from Hebrew: Pes) is a Christian festival and holiday celebrating the resurrection of Jesus Christ on the third day after his crucifixion at Calvary as described in the New Testament. Easter is the culmination of the Passion of Christ, (Continued On Page 11) 5” X 2” 206-501-2254/281-381-0744 [email protected] inside March 2013 T is for Teaching.........03 Meet Flu Virus............03 Taste For Alcohol........04 Kid President..............04 Calorie From Fast Food05 Heart Disease.............06 Accpunture.................07 Hign Fat Diets.............08 People Are Bad At Learning............................09 Giving Makes People Feel APRIL 2013 REAL ESTAT SPECIAL info@seattle southasian.com 206-501-2254 Better Than Getting....10 Whale Got TheirTeeth.11 First Space Tourist......12 Air Pollution Linked To Early Death................13 How Insects Find ‘Mr. Rig ht’............................15 Community Calendar...15 Milky Way..................16 Kids With TV Addiction17 Secret Code Used.......18 Potential Drug Target For Cancer Identified.......19 Heavy Internet Users..20 Low Intensity Exercise.20 Astrology....................21 Entertainment........22,23 Seattle South Asian |March 2013 Page 2 Something Big is Coming to Vancouver! Be here for all the excitement! The Times of India Film Awards are coming to Vancouver, bringing Bollywood’s hottest stars to the city from April 4th to 6th. Whether you’re attending the big gala awards, a TOIFA concert, film screenings, or just star-gazing, make a night of it by booking a hotel downtown. BOOK NOW FOR TOIFA HOTEL PACKAGE SPECIALS! While supplies last, we have a limited number of special packages that include accommodations, parking and awards tickets. Book now at www.tourismvancouver.com/TOIFA Seattle South Asian |March 2013 Page 2 Page 3 Seattle South Asian |March 2013 “T” Is For “Teaching” And “T” Is For “Tradition” By Alpana Deo My Previous article “Be Their Role Model” talked about how even our small day-to-day gestures, activities can be a learning experience to our kids and how much importance these gestures, activities give to how we talkreact and deal with any situation. Usually, I like and prefer to associate my chosen topic to my personal experience. Last month was the Makar Sankranti month. It ended on Feb 11th. We all have celebrated this festival in our own traditional way. In Maharashtra, we make Gulachi Poli(flat bread stuffed with soft/shredded Jaggery mixed with toasted, ground Til- sesame seeds) and Khichadi on Sankranti day i.e January 14. We have a saying ‘Til GuL Ghya Aani God God Bola’ meaning ‘Accept this tilgul and speak sweetly’. My daughter is 4 years old. She is at the right age when she can remember these small things. As they say in Parle-G commercial “Bachpan Se Bada koi School Nahi, Curiosity Se Badi Koi Teacher Nahi”. Like any other kid she was also curious and surprised but quite confused that why everyone is saying these words. She asked me is it because we are eating Gulachi Poli and its sweet? I told her that we have Sankranti in the beginning of the year so by saying this it gives us a chance to remember that we should never hurt anybody’s feeling, always try to speak sweet. She got it. Second part of this festival is Haldi Kunku or Haldi Kumkum (literally meaning turmeric and vermillion). Every year I try to have at least a small Haldi Kumkum at my place. All this is to maintain and to let our daughter know about the traditional practices associated to this festival. Sometimes, I feel living in the USA brings us more close to our culture. We put extra efforts in bringing India into our homes during these festival seasons. We do it with more dedication, devotion. Again going back to my personal experience, I grew up in Uttar Pradesh. If my parents hadn’t put their extra efforts in maintaining Maharashtrian culture, tradition at our home then I don’t think it would have been possible for me to write on this topic. For example calling kid’s friends on such occasions as we do on birthdays and involving them in deciding what to do, picking gifts will help them to remember the occasion and the customs related to it. Every year they will look forward for this time of the year to come. What else could be more satisfying for us as a parent living here when our kids remember and show their enthusiasm and interest in these small things and expects just a tiny bit of encouragement from us for their involvement. Everyone is busy today. Quite often we get to hear people saying that we don’t get time to do all this traditional things. We want to do but don’t know how. Not as a comment but these are few words that I have recently read in a book. “We all have 24 hours; it’s not the time that matters but the activities that we get engaged into during these 24 hours. We have to prioritize them. If we really want to do something then it’s not that difficult to spare some extra minutes out of our daily schedule to implement and execute it.” Little bit of planning and an inner zeal are the only two requirements for giving our kids this great gift of tradition. FREE CLASSIFIED Birthday Greetings Wedding Anniversary Promotions Achievements 25 words Email or on before 15 th of every month to info@ Seattle southasian.com Believe me, they enjoy it, they really do... Meet ‘Flu Virus’ New Enemy Washington, February 22 (ANI): An international group of scientists has discovered a new class of molecular compounds capable of killing the influenza virus. Their new compounds will lead to a new generation of anti-influenza drugs that the virus’ strains can’t adapt to, and resist, as easily as they do Tamiful – the anti-influenza drug that is becoming less effective against the constantly mutating flu virus. Working on the premise that too much of a good thing can be a Page 3 killer, the team that include Simon Fraser University virologist Masahiro Niikura and his doc- toral student Nicole Bance have advanced previous researchers’ methods of manipulating an enzyme that is key to how influenza replicates and spreads. They have described how to use their newly discovered compounds to interrupt the enzyme neuraminidase’s facilitation of influenza’s spread. Tamiful and another anti-influenza drug, Relenza, focus on interrupting neuraminidase’s ability to help influenza detach from an infected cell’s surface by digesting sialic acid, a sugar on the surface of the cell. The flu virus uses the same sugar to stick to the cell while invading it. Once attached, influenza can invade the cell and replicate. This is where the newly discovered compounds come to the still-healthy cells’ rescue. They clog up neuraminidase, stopping the enzyme from dissolving the sialic acid, which prevents the virus from escaping the infected cell and spreading. The new compounds are also more effective because they’re water-soluble. “They reach the patient’s throat where the flu virus is replicating after being taken orally,” said Niikura, a Faculty of Health Sciences associate professor. “Influenza develops resistance to Replenza less frequently, but it’s not the drug of choice like Tamiful because it’s not water-soluble and has to be taken as a nasal spray. “Our new compounds are structurally more similar to sialic acid than Tamiful. We expect this closer match will make it much more difficult for influenza to adapt to new drugs,” Niikura explained. Ultimately, the new compounds will buy scientists more time to develop new vaccines for emerging strains of influenza that are resistant to existing vaccines. Their study has been published in the journal Science Express. (ANI) Seattle South Asian |March 2013 Seattle South Asian |March 2013 Page 4 ‘Artificial Brain’ Lets Robots Learn Language Washington, February 20 (ANI) An artificial brain system enabled a robot to learn, and subsequently understand, new sentences containing a new grammatical structure. INSERM and CNRS researchers and the Universite Lyon 1 have succeeded in developing an “artificial neuronal network” constructed on the basis of a fundamental principle of the workings of the human brain, namely its ability to learn a new language. Thanks to so-called recurrent construction (with connections that create locally recurring loops) this artificial brain system can understand new sentences having a new grammatical structure. It is capable of linking two sentences and can even predict the end of a sentence before it is provided. The model was developed after years of research in the INSERM 846 Unit of the Institut de recherche sur les cellules souches et cerveau, through studying the structure of the human brain and understanding the mechanisms used for learning. To put this advance into a real-life situation, the INSERM researchers incorporated this new brain into the iCub humanoid robot. In a video demonstration, a researcher asks the iCub robot to point to a guitar (shown in the form of blue object) then asking it to move a violin to the left (shown by a red object). Before performing the task, the robot repeats the sentence and explains that it has fully understood what it has been asked to do. For researchers, the contribution that this makes to research into certain diseases is of major importance. Taste For Alcohol `Originated 10 Mn Yrs Ago In Common Ancestor Of Humans And Chimps` way. Washington, February 20 (ANI): These reactions could hitherto be recorded by sensors placed on the scalp”, explained Dr Peter Ford Dominey. The ability to metabolize ethanol — the alcohol in beer, wine and spirits — might have originated in the common ancestor of chimpanzees, gorillas and humans roughly 10 million years ago, perhaps when this ancestor became more terrestrial and started The model developed by Dr Xavier Hinaut and Dr Dominey makes it possible to identify the source of these responses in the brain. Among primates, not all ADH4s are the same — some can’t effectively metabolize ethanol. To see how ADH4 evolved, Benner’s team read the stretches of DNA that make ADH4 in 27 modern primate species, including lemurs, monkeys, apes and humans. If this model, based on the organisation of the cerebral cortex, is accurate, it could contribute to possible linguistic malfunctions in Parkinson’s disease. This research has another important implication, that of contributing to the ability of robots to learn a language one day. This research has been published in the Plos One journal. (ANI) This system can be used to understand better the way in which the brain processes language. “We know that when an unexpected word occurs in a sentence, the brain reacts in a particular Kid President And Obama Announce 2013 White House Easter Egg Roll Washington, February 22 (ANI): President Obama took the help of Kid President -- a.k.a. nine-year-old Robby Novak – to announce the 2013 lottery for the annual White House Easter Egg Roll. Kid President -- the “self-appointed voice of a generation” -- got a call from the real president about Easter Egg Roll, according to ABC News. “Kid President, looks like you got my message,” Obama said in a video released by the White House on Thursday. “Yes Mr. President, I got your message,” Kid President responded over a tin can phone before talking about the “historic” Easter egg roll. As for his response to the Easter Egg Roll, he told the president, “This is historic … Kids dancing. Eggs rolling. I’m in!” The nine-year-old later announced that the ticket lottery for the April 1 White House Easter Egg roll is open, and closes on Monday, Feb. 25. (ANI) Seattle South Asian |March 2013 eating fruits fermenting on the ground, according to scientists. Chemist Steven Benner of the Foundation for Applied Molecular Evolution in Gainesville, Fla., reached that conclusion by “resurrecting” the alcohol-metabolizing enzymes of extinct primates. Benner and his colleagues estimated the enzymes’ genetic code, built the enzymes in the lab and then analyzed how they work to understand how they changed over time. Today, humans rely on an enzyme called alcohol dehydrogenase 4, or ADH4, to break down ethanol. The enzyme is common throughout the esophagus, stomach and intestines, and is the first alcoholmetabolizing enzyme that comes into contact with what a person drinks. Then they mapped the DNA sequences on a primate family tree and inferred what the genes might have looked like long ago at points on the tree where evolutionary branches separated. The branching points represent extinct primate ancestors. Most primate ancestors wouldn’t have been able to metabolize ethanol, the results showed. But at the branching point leading to gorillas, chimps and humans — which represents an ancestor that lived roughly 10 million years ago — the enzyme becomes a powerful alcohol digester. Compared with earlier enzymes, this one was 50 times as efficient, Benner reported, and was nearly capable of breaking down the level of ethanol found in modern alcoholic beverages. (Continued On Page 06) Page 4 Page 5 Seattle South Asian |March 2013 PAMV is about telling children that consumption of violent content in media can have adverse health impacts. Join the Parent group today. 11Pc Of Adult’S Calories Come From Fast Food Washington, February 22 (ANI): A new U.S. report has revealed that 11.3 percent of daily calories consumed by adults in 2007 through 2010 came from fast food. Non-Hispanic black adults ate more fast food in their diet than non-Hispanic whites and Hispanic adults. Non-Hispanic blacks have the highest rates of obesity at 49.5 percent, according to the CDC. The report from the Centers for Disease Control and Prevention was based on data However, there were no differences in the amount of fast food consumed by adults when income status was taken into ac- pulled from the National Health and Nutrition Examination Survey (NHANES), CBS News reported. count. But, for young adults, the higher the income they reported, the lower the chances they ate fast food. Fast food is a quick alternative to making a meal at home, and it’’s steadily becoming am increasing part of the American diet, the report noted. “The good news from this study is that as we get older, perhaps we do get wiser and eat less fast food,” Samantha Heller, a clinical nutritionist at the NYU Center for Musculoskeletal Care in New York City told HealthDay. www.PAMV.org [email protected] | 248-677-5523 MARKETING ASSOCIATES WORK FROM HOME Looking for opportunity to work from home? Choose your own flexible time. Don’t leave your home. Job Requirements: a. Need to speak English - if you love to talk this is your job b. Need to know how to use computer, Internet and email. We pay commission up to 20% plus 5% bonus. We will provide you all the support and help. Email your brief resume and we will get in touch with you: [email protected] A To Z Taxes Inc. Visit Us at www.atoztaxesinc.com Page 5 However, the 2007 to 2010 fast foodcalorie statistics are lower than the levels reported from 2003 to 2006, when the American diet was about 13 percent fast food, it said. Researchers cited that eating fast food frequently has been linked to weight gain. The CDC report revealed that more than one-third of U.S. adults are obese and that obese people had the highest percentage of fast food making up their diet. But Heller pointed out that bad food habits in a person’’s 20s can set them up for a lifetime of disease,adding that eating poorly early in life can lead to metabolic syndrome, diabetes, cancer and cardiovascular disease. “A take-home message is that the study suggests that the more fast food you eat, the fatter you get,”she said. (ANI) ORACLE FINANCIAL TRAINING www.appssys.com 281-381- 0744 Seattle South Asian |March 2013 Seattle South Asian | March 2013 Page 6 Mercury May Have Taste For Alcohol `Originated 10Mn Yrs Ago In Common Ancestor Of Humans And Chimps` Harbored ‘Vast Magma Ocean’ 4.5 Billion Years Ago (Continued From Page 05) Washington, February 22 (ANI): Based on the chemical composition of rocks on Mercury’s surface, scientists at MIT have proposed that the planet may have harbored a large, roiling ocean of magma very early in its history, shortly after its formation about 4.5 billion years ago. The scientists analyzed data gathered by MESSENGER (MErcury Surface, Space ENvironment, GEochemistry, and Ranging), a NASA probe that has orbited the planet since March 2011. Later that year, a group of scientists analyzed X-ray fluorescence data from the probe, and identi- fied two distinct compositions of rocks on the planet’s surface. thetic rock to high temperatures and pressures to simulate various geological processes. From their experiments, the scientists came up with only one phenomenon to explain the two compositions: a vast magma ocean that created two different layers of crystals, solidified, then eventually remelted into magma that then erupted onto Mercury’s surface. “The thing that’s really amazing on Mercury is, this didn’t happen yesterday. The discovery unearthed a planetary puzzle: What geological processes could have given rise to such distinct surface compositions? To answer that question, the MIT team used the compositional data to recreate the two rock types in the lab, and subjected each syn- The crust is probably more than 4 billion years old, so this magma ocean is a really ancient feature,” said Timothy Grove, a professor of geology at MIT. Grove, along with postdoc Bernard Charlier and Maria Zuber, the E.A. Griswold Professor of Geophysics and Planetary Science and now MIT’s vice president for research, published the results in the journal Earth and Planetary Science Letters. (ANI) Because gorillas, chimps and humans all spend at least some time on the ground, Benner thinks a terrestrial lifestyle arose in these primates’ common ancestor around 10 million years ago. Being on the ground, the ancestor would have come across fruit that had fallen from trees. With a damaged husk or skin, yeast could have invaded the fruit and fermented its sugars into ethanol. Thus, individuals who could digest ethanol would have survived better than those who couldn’t. This would also explain why the ability to metabolize ethanol didn’t evolve in tree-dwelling primates like orangutans that rarely encounter fermented fruit. But it may be too soon to link metabolizing ethanol with living on the ground, said Jeremy DeSilva, a biological anthropologist at Boston University. “There’s very little fossil evidence from the general time period when humans, gorillas and chimpanzees last shared a common ancestor,” DeSilva noted. (ANI) Dubai Set To Build World’s Biggest Ferris Wheel Wellington, Feb 14 (ANI): A 210 metre Ferris wheel is set to become the world’s biggest Ferris wheel after its addition on the top of the Burj Khalifa tower in Dubai, according to the country’s ruler. According to reports, the wheel which has been named as the Dubai Eye, is expected to dwarf the London Eye (135 m), a giant Ferris wheel situated in London, Stuff.co.nz reports. The wheel, whose construction is expected to begin this year, is a part of an island development project worth 1.6 billion US dollars which was approved by the ruler. Dubai has proposed a series of mega projects reminiscent of its boom years before the downturn hit in 2009, which include theme parks and a satellite city named after the ruler. (ANI) High Cholesterol’s Role In Heart Disease Busted As A ‘Myth’ Washington, Feb. 18 (ANI): A doctor from California has claimed that it’s a myth that high cholesterol is one of the factors, which makes the heart diseases deadly. Dr. Jonny Bowden, author of ‘The Great Cholesterol Myth,’ said that lowering your cholesterol may not necessarily prevent heart disease. He said that cholesterol is not even a good predictor of heart disease. He asserted that 50 percent of people who are admitted to hospitals in the US with cardiovascular disease have normal cholesterol and half the people with elevated cholesterol have normal hearts, Fox News reported. He also believes that cholesterol plays no role whatsoever in the development of heart disease, and that it has taken atten- Seattle South Asian | March 2013 tion away from other important factors that contribute to cardiovascular problems – like inflammation, oxidative damage, stress and sugar in the diet. He believes that cholesterol is a pretty minor player but still everyone puts all their efforts into lowering it. Today, doctors know that there are two main types of cholesterol - HDL and LDL - and there are five different kinds of each. He said that both the types behaved quite differently in the body adding that while LDL comes in two big flavours, LDLA and LDL-B, LDL-A looked like a big cotton ball and it can’t do any damage as it can’t get caught in the arteries. He added that LDL-B is a bad guy - but most people don’t know which one they have. (ANI) READ SEATTLE SOUTH ASIAN Page 6 Seattle South Asian |March 2013 Page 7 Is coffee drinking related to mortality? Washington, February 20 (ANI): As coffee drinking increased, the risk of death decreased. and various specific causes of disease in an interview in Journal of Caffeine Research, a peer- This is what a large study of nearly half a million older adults followed for about 12 years has found. Study author Neal Freedman, PhD, MPH, National Cancer Institute, discusses the significance of these findings and the potential links between coffee drinking, caffeine consumption, reviewed journal from Mary Ann Liebert, Inc., publishers. Dr. Freedman examines the rela- tionship between coffee drinking and behaviors such as smoking and alcohol abuse, the physiological effects of caffeine on blood pressure and cardiac function, and the importance of differentiating between the effects of coffee and caffeine. Why You Should Worry If You’re Over 22 And Suffering From Cold? London, February 20 (ANI): Pittsburgh researchers have identified telomere length as a marker that can predict who is most likely to get colds. “Given the near-universal daily consumption of caffeine, Dr. Freedman’s research underscores the urgent need for randomized controlled trials to identify which components of coffee and other caffeine beverages benefit or harm consumers, under what circumstances, and in relation to which health outcomes,” said Jack E. James, PhD, Editor-inChief of Journal of Caffeine Research. (ANI) days to see if they actually developed an infection. They saw that the participants with shorter telomeres were more likely to become infected by the cold virus. Acupuncture May Help Relieve Seasonal Allergies Washington, February 20 (ANI) Researchers studied the effect of acupuncture over eight weeks be due to an effect on the immune system. In some cases, it appeared a reduction in the amount of allergy m e d i cations might be possible, they said. T h e y suggested that acupuncture m i g h t be helpful when combined w i t h We s t e r n treatments. Acupuncture may help relieve seasonal allergy symptoms in some people with runny noses and watery eyes, according to a recent study out of Germany - but the effect seems to be small. and reported a decrease in allergy symptoms, according to Fox News. But they said that patients should discuss with their allergist before changing or stopping any medications. The exact mechanism is not known or even clear; however, the researchers believe that it may The study was published in the Annals of Internal Medicine. (ANI) Seattle South Asian |March 2013 Telomeres are tiny protective structures that sit at the end of every single chromosome in the body. They act like a plastic cap at the end of a shoelace, preventing DNA unravelling every time the body’’s cells divide. As we age, they get shorter, making us more susceptible to illness. However, until now it was not known whether telomere length play a role in the health of young to middle-aged adults, said the researchers from Carnegie Mellon University, Philadelphia. Now, they have found that telomere length does predict our resistance to upper respiratory infections when we are in our 20s, the Daily Mail reported. “Our work suggests the possibility that telomere length is a relatively consistent marker across the life span and that it can start predicting disease susceptibility in young adulthood,” said Professor Cohen. But he noted that this is preliminary research and further work with other viruses and with natural infections will help clarify its implications. The findings were published in the Journal of the American Medical Association. (ANI) HAPPY Mar 24 - World TB Day Lead researcher Professor Sheldon Cohen and his team measured the telomere length of white blood cells from 152 healthy volunteers aged 18 to 55. Mar 27 - Holi They were then exposed to a rhinovirus, which causes a common cold, and quarantined for five Mar 31 - Easter Mar 29 - Good Friday Page 7 Seattle South Asian |March 2013 Page 8 High-Fat Diets May Cause ADHD In Children Washington, February 20 (ANI) High-fat diets and brain-based conditions childhood like attention deficit hyperactivity disorder (ADHD) and memory-dependent learning disabilities may be linked, according to new research released by the University of Illinois. “We found that a high-fat diet rapidly affected dopamine metabolism in the brains of juvenile mice, triggering anxious behaviors and learning deficiencies. Interestingly, when methylphenidate (Ritalin) was administered, the learning and memory problems went away,” said Gregory Freund, a professor in the U of I College of Medicine and a member of the university’’s Division of Nutritional Sciences. Freund said that altered dopamine signaling in the brain is common to both ADHD and the overweight or obese state. “And an increase in the number of dopamine metabolites is associated with anxiety behaviors in children,” he added. Intrigued by the recent upsurge in both child obesity and adverse childhood psychological conditions, including impulsivity, depression, and ADHD, Freund’’s team examined the short-term effects of a high-fat (60 percent calories from fat) versus a low-fat (10 percent calories from fat) diet on the behavior of two groups of four-week-old mice. A typical Western diet contains from 35 to 45 percent fat, he said. “After only one week of the highfat diet, even before we were able to see any weight gain, the behavior of the mice in the first group began to change,” he said. Evidence of anxiety included increased burrowing and wheel running as well a reluctance to explore open spaces. The mice also developed learning and memory deficits, including decreased ability to negotiate a maze and impaired object recognition. Switching mice from a high-fat to a low-fat diet restored memory in one week, he noted. In mice that continued on the high-fat diet, impaired object rec- ognition remained three weeks after the onset of symptoms. But Freund knows from other studies that brain biochemistry normalizes after 10 weeks as the body appears to compensate for the diet. At that point, brain dopamine has returned to normal, and mice have become obese and developed diabetes. “Although the mice grow out of these anxious behaviors and learning deficiencies, the study suggests to me that a high-fat diet could trigger anxiety and memory disorders in a child who is genetically or environmentally susceptible to them,” he said. Because the animals adapt to the high-fat fare, the scientists also hypothesized that abruptly removing fat from the diet might negatively affect anxiety, learning, and memory. The researchers had expected that the high-fat diet would stimulate inflammation, which is associated with obesity, but they saw no evidence of an inflammatory response in the brain after one or three weeks on the high-fat regimen. Instead, they saw evidence that a high-fat diet initiates chemical responses that are similar to the ones seen in addiction, with dopamine, the chemical important to the addict’’s pleasurable experiences, increasing in the brain. The study was published in Psychoneuroendocrinology. (ANI) How sweat protects people from dangerous bugs Washington, February 22 (ANI): bacteria. Scientists has discovered how an Scientists from the University of important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs. Their results could contribute to the development of new antibiotics that control multi-resistant Edinburgh and from Goettingen, Tuebingen and Strasbourg have uncovered the atomic structure of the compound, enabling them to pinpoint for the first time what makes dermcidin such an efficient weapon in the battle against dangerous bugs. Seattle South Asian |March 2013 Although about 1700 types of these natural antibiotics are known to exist, scientists did not of a mosquito, antibiotic agents secreted in sweat glands, such as dermcidin, rapidly and efficiently kill invaders. These natural substances, known as antimicrobial peptides (AMPs), are more effective in the long term than traditional antibiotics, because germs are not capable of quickly developing resistance against them. membrane of bugs, which are stabilised by charged particles of zinc present in sweat. The team also discovered that dermcidin can adapt to extremely variable types of membrane. until now have a detailed understanding of how they work. The antimicrobials can attack the bugs’’ Achilles’’ heel – their cell wall, which cannot be modified quickly to resist attack. Because of this, AMPs have great potential to form a new generation of antibiotics. Sweat spreads highly efficient antibiotics on to our skin, which protect us from dangerous bugs. Scientists have known for some time that dermcidin is activated in salty, slightly acidic sweat. If our skin becomes injured by a small cut, a scratch, or the sting The molecule then forms tiny channels perforating the cell As a consequence, water and charged particles flow uncontrollably across the membrane, eventually killing the harmful microbes. Through a combination of techniques, scientists were able to determine the atomic structure of the molecular channel. They found that it is unusually long, permeable and adaptable, and so represents a new class of membrane protein. Scientists said this could explain why active dermcidin is such an efficient broad-spectrum antibiotic, able to fend off bacteria and fungi at the same time. The international team of scientists hopes that their results can contribute to the development of a new class of antibiotics that is able to attack such dangerous germs. The study has been published in Proceedings of the National Academy of Sciences. (ANI) Page 8 Seattle South Asian |March 2013 Page 9 Renewed Hope For Comprehensive Immigration Reform (Continued From Page 01) rently living in the United States. Congress and the high partisan tensions of the past few years, immigration reform still faces many obstacles; Providing a way to legalize undocumented immigrants has been among the greatest sources of disagreement between the two parties; the fact that there is now significant bipartisan agreement on a pathway to citizenship, at least in principle, is very encouraging. however, Republicans’ extremely poor performance among Asian Americans and Latinos in the 2012 elections and encouraging statements by leaders in both parties bode well for the prospect of a successful compromise. A bipartisan group of eight Senators, four Democrats and four Republicans, announced their plan on Monday, and the President followed with a speech in Nevada on Tuesday. Both plans are based on the same basic principles: improving border security, cracking down on the hiring of illegal workers, streamlining and improving the immigration system for future immigrants, and perhaps most importantly, a pathway to citizenship for the estimated 11 million undocumented immigrants cur- While many Americans think of Latinos when they think of undocumented immigrants, five of the top ten countries of origin for undocumented immigrants are China (280,000), the Philippines (270,000), India (240,000), Korea (230,000), and Vietnam (170,000). Both plans also emphasize that the current immigration system is far too inefficient and bureaucratic, and its delays and complexities drive away the most desirable immigrants. Particularly encouraging for the Asian American community, who often rely on skilled worker and student visas to come to the US, both plans call for making it easier for skilled workers and those holding or obtaining advanced degrees in science, technology, engineering, and math to immigrate to the US, as well as increasing the numbers of such immigrants. Both proposals also call for helping investors and entrepreneurs obtain green cards more easily. On the other hand, there are also serious points of disagreement between the two proposals. President Obama’s plan also emphasizes the need to streamline the process for family reunification, another area heavily relied on by Asian immigrants, while the Senate proposal does not focus much on this area; some Republicans have indicated that family immigration numbers would actually be reduced to accommodate more skilled workers, advanced degree holders, investors, and entrepreneurs. Perhaps the area of greatest concern is the difference between the two proposals on the timing of the pathway to citizenship for undocumented immigrants. While both proposals would require undocumented immigrants to take similar steps on their path to legalization, including a criminal background check, paying back taxes and fines, obtaining work, and going to the back of the line, the Senate proposal would not open up the path until certain triggers for immigration enforcement and border security are met first. President Obama’s speech indicated that some process for undocumented immigrants to obtain legal status would be developed at the same time as enforcement and security efforts, and he also highlighted the need for a quicker path for undocumented immigrants brought here as children, often known as DREAMers after the proposed DREAM Act, which narrowly failed to pass Congress in December 2010. If something similar to the Senators’ or President’s proposals passes, it will be the most significant reform of US immigration law since the Immigration Reform and Control Act of 1986. For all those waiting to be reunited with their family, those seeking to better themselves through education, those eager to bring their entrepreneurial energy and talent to America, and those who have called America home for almost their entire lives, that day cannot come soon enough. Ramey Ko is a partner at Jung Ko, PLLC, an immigration and business law firm in Austin, Texas, a Lecturer at the University of Texas, and an Associate Municipal Judge. He is a graduate of Yale University and the University of Chicago Law School. Why Some People Are Bad At Learning Washington, February 14 (ANI): A research team has revealed the reason why some people are worse at learning than others. They have discovered that the main problem is not that learning processes are inefficient per se, but that the brain insufficiently processes the information to be learned. The researchers from the RuhrUniversitat, the Humboldt Universitat zu Berlin, Charité – Universitatsmedizin Berlin and the Max Planck Institute (MPI) for Human Cognitive and Brain Sciences trained the subjects’ sense of touch to be more sensitive. In subjects who responded well to the training, the EEG revealed characteristic changes in brain activity, more specifically in the alpha waves. These alpha waves show, among other things, how effectively the brain exploits the sensory information needed for learning. “An exciting question now is to what extent the alpha activity can be deliberately influenced with biofeedback. This attention”, said Hubert Dinse. The researchers were, therefore, able to exclude attention as a factor. They repeatedly stimulated the participants’ sense of touch for 30 minutes by electrically stimulating the skin of the hand. could have enormous implications for therapy after brain injury or, quite generally, for the understanding of learning Before and after this passive training, they tested the so-called “two-point discrimination threshold”, a measure of the processes,” said PD Dr. Hubert Dinse from the Neural Plasticity Lab of the Ruhr-Universität Bochum. sensitivity of touch. For this, they applied gentle pressure to the hand with two needles and determined the smallest How well we learn depends on genetic aspects, the individual brain anatomy, and, not least, on attention. distance between the needles at which the patient still perceived them as separate stimuli. On average, the passive “In recent years we have established a procedure with which we trigger learning processes in people that do not require training improved the discrimination threshold by twelve percent—but not in all of the 26 participants. Using EEG, the Seattle South Asian |March 2013 team studied why some people learned better than others. The cooperation partners from Berlin and Leipzig, PD Dr. Petra Ritter, Dr. Frank Freyer, and Dr. Robert Becker recorded the subjects’ spontaneous EEG before and during passive training. learned. These effects occurred in the somatosensory cortex, that is, where the sense of touch is located in the brain. A high level of alpha activity counts as a marker of the readiness of the brain to exploit new incoming information. They then identified the components of the brain Conversely, a strong decrease of alpha activity during sensory stimulation counts as an indicator that the brain processes activity related to improvement in the discrimination test. The alpha activity was decisive, i.e., the brain activity was stimuli particularly efficiently. The results, therefore, suggest that perception-based learning is highly dependent on in the frequency range 8 to 12 hertz. how accessible the sensory information is. The alpha activity, as a marker of constantly changing brain states, modulates The higher the alpha activity before the passive training, the better the people learned. In addition, the more the alpha activity decreased during passive training, the more easily they this accessibility. The research team reported their findings in the Journal of Neuroscience. (ANI) Page 9 Seattle South Asian | March 2013 Page 10 Sleeping On It Can Help You Make Decisions Washington, February 14 (ANI): When faced with a difficult decision, people may think of “sleeping on it” or taking a break from thinking about the decision in or- that lead to improved decisionmaking. “This research begins to chip away at the mystery of our unconscious brains and decisionmaking,” said J. David Creswell, not have any awareness that their brains were still working on the decision problem while they were engaged in an unrelated task,” he stated. For the study, Creswell, recent CMU graduate James K. Bursley and Northeastern University’s Ajay B. Satpute presented 27 healthy adults with information about cars and other items while undergoing neuroimaging. Then, before being asked to make decisions about the items, the participants had to complete a difficult distractor task — memorizing sequences of numbers — to prevent them from consciously thinking about the decision information. der to gain clarity. But a new brain imaging research from Carnegie Mellon University, has found that the brain regions responsible for making decisions continue to be active even when the conscious brain is distracted with a different task. The research provides some of the first evidence showing how the brain unconsciously processes decision information in ways assistant professor of psychology in CMU’s Dietrich College of Humanities and Social Sciences and director of the Health and Human Performance Laboratory. “It shows that brain regions important for decision-making remain active even while our brains may be simultaneously engaged in unrelated tasks, such as thinking about a math problem. What’s most intriguing about this finding is that participants did The results included three main findings. First, the team confirmed previous research demonstrating that a brief period of distraction — in this case two minutes — produced higher quality decisions about the cars and other items. But did this effect occur because the distraction period provided an opportunity for the brain to take a break from decision-making and then return to the problem with a fresh look? Or alternatively, Giving Makes People Feel Better Than Getting Washington, February 22 (ANI): Spending money on someone else rather than for personal benefit makes people feel good both rich and poor nations, according to a new research. Our findings suggest that the psychological reward experienced from helping others may be deeply ingrained in human nature, emerging in diverse cultural and economic contexts, said lead author Lara Aknin, PhD, of Simon Fraser University in Canada. The findings provide the first empirical evidence that “the warm glow” of spending on someone else rather than on oneself may be a widespread component of human psychology, said the researchers. Researchers found a positive re- lationship between personal wellbeing and spending on others in 120 of 136 countries covered in the 2006-2008 Gallup World Poll. The survey comprised 234,917 individuals, half of whom were male, with an average age of 38. The link between well-being and spending on others was significant in every region of the world, and it was not affected by other factors among those surveyed, such as income, social support, perceived freedom and perceived national corruption, the study said. The results were similar in several experiments the researchers themselves conducted with participants in wealthy and poor countries. The researchers obtained the same results when they conduct- Seattle South Asian | March 2013 ed an online survey of 101 adults in India. Some respondents were asked to recall recently spending money on themselves or someone else, while others were tested for their happiness level without recalling past spending. Those who recalled spending on someone else said they had a greater feeling of well-being than those who remembered spending on themselves or those who weren’’t asked about spending. “From an evolutionary perspective, the emotional benefits that people experience when they help others acts to encourage generous behavior beneficial to long-term human survival,” said Aknin. The study was published online in APA’’s Journal of Personality and Social Psychology. (ANI) does the brain continue to unconsciously process decision information during this distraction period? This research supports the latter unconscious processing explanation. When the participants were initially learning information about the cars and other items, the neuroimaging results showed activation in the visual and prefrontal cortices, regions that are known to be responsible for learning and decision-making. Additionally, during the distractor task, both the visual and prefron- tal cortices continued to be active — or reactivated — even though the brain was consciously focused on number memorization. Third, the results showed that the amount of reactivation within the visual and prefrontal cortices during the distractor task predicted the degree to which participants made better decisions, such as picking the best car in the set. The study was published in the journal “Social Cognitive and Affective Neuroscience.” (ANI) Sitting Time Influences Risk Of Chronic Diseases Washington, February 20 (ANI): Sitting for long periods can raise your risk of chronic diseases, a new study has warned. Kansas State University researcher Richard Rosenkranz, assistant professor of human nutrition, examined the associations of sitting time and chronic diseases in middle-aged Australian males. The study’’s sample included 63,048 males ages 45-65 from the Australian state of New South Wales. Study participants reported the presence or absence of various chronic diseases, along with their daily sitting time: categorized as less than four hours, four to six hours, six to eight hours, or more than eight hours. Compared with those who reported sitting four hours or less per day, those who sat for more than four hours per day were significantly more likely to report having a chronic disease such as cancer, diabetes, heart disease and high blood pressure. The reporting of chronic diseases rose as participants indicated they sat more. Those sitting for at least six hours were significantly more likely to report having diabetes. “We saw a steady stair-step increase in risk of chronic diseases the more participants sat,” Rosenkranz said. “The group sitting more than eight hours clearly had the highest risk.” The study is relevant to office workers sitting at desks and those sitting for long periods of time such as truck drivers, he said. “We know that with very high confidence that more physically active people do better with regard to chronic disease compared with less physically active people, but we should also be looking at reducing sitting,” Rosenkranz said. “A lot of office jobs that require long periods of sitting may be hazardous to your health because of inactivity and the low levels of energy expenditure.” Researchers said that although most of the current evidence is suggestive of a causal connection, they cannot be certain in this study whether volumes of sitting time led to the development of chronic diseases or whether the chronic diseases influenced sitting time. “It’’s a classic case of, ‘’Which came first: the chicken or the egg?’’” Rosenkranz said. The study has been published in the International Journal of Behavioral Nutrition and Physical Activity. (ANI) Page 10 Seattle South Asian |March 2013 Page 11 How Whales Got Their Teeth Washington, February 20 (ANI): A multidisciplinary team of researchers has married together the fossil record and the embryonic development process to investigate how the whale got its teeth. In most mammals there are wedge-shaped incisors, a pointy canine, and premolars and molars with bumps and valleys that fit Next, Armfield and her colleagues explored just how teeth are shaped during development. Specific proteins in the embryo and this occurs near the tip of the jaws, where the incisors form. Prior to teeth forming in the embryo, FGF8 expression in the Next, the authors moved on to examine dolphin embryos. Here, the pattern was different: FGF8 is present in the back part of the jaw, but BMP4 is present along the entire length of the jaw, including where FGF8 is found. Not all whales have teeth, but those that do, such as killer whales, have rows of simple peg like teeth, each one looking the same as the next. Whales use this spiked row of teeth to grab prey, but unlike other mammals, whales do not chew. In a new study, Brooke Armfield and colleagues investigated the developmental processes that cause the teeth of dolphins, whales’’ smaller cousins, to be different, and tracked the evolutionary progression of their unique dentition across the fossil record. Whales evolved from land mammals and so Armfield and coworkers first went to the fossil record to trace when and how whales evolved their simple teeth. The fossil record shows that, 48 million years ago, whales had the same four kinds of teeth just like most other mammals. Most mammals have four kinds of teeth, each shaped for specific tasks. of teeth, and, sure enough, the two proteins are distributed in the same way as they are in other mammals, showing that whales’’ ancestors likely had this distribution of gene expression too. The researchers hypothesize that the overlapping presence of BMP4 in these new areas causes the teeth all along the jaw to be simple in shape, like incisors, and to be similar to each other. Interestingly, other researchers had shown that in mouse embryos in which BMP4 is experimentally introduced in the back of the jaw, the back teeth also take on this simplified appearance. together like a mortar and pestle when you chew. cause developing teeth to grow into certain shapes. Gradually, the teeth of whales became simpler and acquired their characteristic peg-like appearance around 30 million years ago, well after the time that they had acquired an array of adaptations for living in the water. Armfield and colleagues zeroed in on two proteins, BMP4 (Bone Morphogenetic Protein 4) and FGF8 (Fibroblast Growth Factor 8). BMP4 expression leads to teeth developing into simple prongs, back of the jaw leads to development of molar teeth with their complex hills and valleys in mice and other mammals. Armfield and her co-workers studied FGF8 and BMP4 in pig embryos, relatives of whales and dolphins. Pigs have the four typical types “The simple shift in the location of proteins that influence tooth shape found in whales may help us to better understand how mammals evolved their complex tooth in the first place,” said Armfield. The research has been published in the open access journal PeerJ. (ANI) MAY 2013 ISSUE EASTER SUMMER SPECIAL TO SEE YOUR AD IN PRINT - CALL 206-501-2254 281-381-0744 Email your contributions to: [email protected] Seattle South Asian |March 2013 (Continued From Page 01) preceded by Lent, a forty-day period of fasting, prayer, and penance. The last week of Lent is called Holy Week, and it contains the days of the Easter Triduum, including Maundy Thursday (Holy Thursday in the Catholic Church), commemorating Maundy and the Last Supper, as well as Good Friday, commemorating the crucifixion and death of Jesus. Easter is followed by a fifty-day period called Eastertide or the Easter Season, ending with Pentecost Sunday. The festival is referred to in English by a variety of different names including Easter Day, Easter Sunday, Resurrection Day and Resurrection Sunday. Easter is a moveable feast, meaning it is not fixed in relation to the civil calendar. The First Council of Nicaea established the date of Easter as the first Sunday after the full moon (the Paschal Full Moon) following the March equinox. Ecclesiastically, the equinox is reckoned to be on 21 March (even though the equinox occurs, astronomically speaking, on 20 March in most years), and the “Full Moon” is not necessarily the astronomically correct date. The date of Easter therefore varies between 22 March and 25 April. Eastern Christianity bases its calculations on the Julian calendar whose 21 March corresponds, during the 21st century, to 3 April in the Gregorian calendar, in which the celebration of Easter therefore varies between 4 April and 8 May. Easter is linked to the Jewish Passover by much of its symbolism, as well as by its position in the calendar. (Continued On Page 13) Page 11 Seattle South Asian |March 2013 Page 12 When Children Can Hop On One Leg First Space Tourist Washington, February 22 (ANI): Motor development in children under five years of age can now be tested reliably by making them do different exercises such as standing on one leg, hopping or running. Together with colleagues from Lausanne, researchers from the University Children’s Hospital Zurich and the University of Zurich have determined normative data for different exercises such as hopping or running. This enables parents and experts to gage the motor skills of young children for the first time objectively and thus identify abnormalities at an early stage. Until now, there has been a lack of reliable data that describes the age from which children are able to stand on one leg, hop on one leg, climb stairs or run. Zurich have now extended this test, simplified it for pre-school children aged between three and five and collected normative data for this age group. The test contains gross and fine motor exercises and additional tasks where children are supposed to run, hop, climb stairs and balance. The tests described in their study reveal that young pre-school children are not yet able to perform certain tasks such as hopping or standing on one leg for longer than two seconds. “Children develop these skills between the age of three and five but very quickly and they are able to at the age of five,” explained Kakebeeke. At the age of three, only forty percent of the children were able to stand on one leg briefly. Such standards have been lacking as it was assumed that motor performance in children under the age of five could not be measured reliably. At five years of age, they all could. As soon as a child was able to do a task and his or her performance was measurable, it was classified on a five-point scale. For children aged between five and eighteen, however, there is an instrument called the Zurich Motor Assessment created by Remo Largo and his team at the University Children’s Hospital Zurich in 2001. The best performance, for example, was thus: The child can stand on one leg – the right and the left – for longer than five seconds. This test procedure is used by many experts to examine neuromotor skills in children of a school age. Neurophysiologist Tanja Kakebeeke and developmental pediatrician Oskar Jenni from the University Children’s Hospital The normative data then developed from the proportion of children who can perform a skill and the actual performance of these children. With the normative data, motor development abnormalities can now be diagnosed at an early stage and therapeutic measures initiated. (ANI) Plans ‘Historic Journey To Mars’ In 2018 Washington, February 22 (ANI): A nonprofit organisation led by Dennis Tito, the first ever space tourist, has announced its intention to launch a mission to Mars in 2018. It is intended to encourage all Americans to believe again in doing the hard things that make our nation great, while inspiring youth through Science, Technology, Engineering and Mathematics (STEM) education and motivation. The proposed launch date is January 2018, and the venture is called “Mission for America.” Tito paid 20 million dollars to be the first paying guest of the International Space Station in 2001, making him the first private space traveller. Now his organization is aiming to Cigarette In 5 Mins Found In China London, Feb 20 (ANI): A rock found in China can inhale a cigarette in under five minutes, it has been revealed. Mystery surrounds the nicotine-addicted rock, which was put on show by collector Luo Yuanshui, from Longyan in southeast China’s Fujian Province. Cigarettes, with variations for length and brand, take around six minutes to burn down naturally if left unsmoked, the Daily Mail reported. Luo said that his puffing pebble knocks an incredible minute off that time, somehow. He said that he found the 2.2kg rock in the mountains of Shangyou. Naturally, his first instinct was to find a hole and pop one of his cigarettes in to see if it would smoke it. He was amazed to discover it did. The oddity is an unidentified red-coloured rock and is fitted with an instructional plaque and a handy ashtray so the marble-boro can neatly indulge in its vice. (ANI) catalyst for future growth, national prosperity, new knowledge and global leadership.” The official description of the mission states: This “Mission for America” will generate new knowledge, experience and momentum for the next great era of space exploration. Called the Inspiration Mars Foundation, the organization is hosting a press conference next Wednesday at the National Press Club in which details of the plans for the trip will be revealed, CNN. com reported. `Smoking Rock` That Can Inhale Seattle South Asian |March 2013 get to Mars and back in 501 days, according to a press release. The press release doesn’t explicitly state that the mission is manned, but it does say that the organization “is committed to accelerating America’s human exploration of space as a critical But noting is revealed about where the money will come from, or how the potential space traveler(s) would survive the journey. (ANI) FREE CLASSIFIED Birthday Greetings Wedding Anniversary Promotions Achievements 25 words Email: info@ Seattlesouthasian.com Page 12 Seattle South Asian |March 2013 Page 13 Air Pollution Linked To Early Death In Heart Attack Survivors Washington, February 20 (ANI) Air pollution is responsible for the sharp rise in deaths among patients who have been admitted to hospital with heart attacks, according to a new study. vironmental epidemiology at the London School of Hygiene and Tropical Medicine (London, UK) said: “We found that for every admitted to hospital with ACS, there would be 20 percent more deaths among patients exposed to PM 2.5 levels of 20 µg/m3, ronmental epidemiology at the London School of Hygiene and Tropical Medicine, estimate that death rates would be reduced by The researchers linked records of 154,204 patients who survived hospital admission for ACS in England and Wales between 2004-2007 with modelled average air pollution concentrations for 2004-2010. The largest study yet to investigate the links between fine air-borne particulate matter (PM) and patient survival after hospital admission for acute coronary syndrome (ACS) found death rates increased with increased exposure to PM2.5 – tiny particles that measure 2.5 micrometers (µm) in diameter or less, approximately 30 times smaller than a human hair. The patients were followed up until the end of the study in April 2010 or their death, whichever occurred earlier. During the average follow-up time of 3.7 years, there were 39,863 deaths. The amount of PM in the air is measured as micrograms per cubic meter of air (µg/m3). The main sources of PM2.5 in the UK are emissions from road traffic and industry, including power generation. Dr Cathryn Tonne, lecturer in en- This translates to 4,783 deaths occurring earlier than they should do, due to exposure to PM2.5 from man-made sources. 10µg/m3 increase in PM2.5 there was a 20 percent increase in the death rate. For example, over one year of follow-up after patients had been DESI SUPPORT SYSTEM - A 501 (C)(3) NON PROFIT ORGANIZATION compared to patients exposed to PM2.5 levels of 10µg/m3.” Dr Tonne and her colleague Paul Wilkinson, professor of envi- 12 percent among ACS patients if they were exposed to naturally occurring PM2.5 rather than the higher levels they were actually exposed to. The researchers adjusted their results to take account of the patients’’ sex, age, medical history, treatments and drugs, whether or not they smoked, socioeconomic factors such as income, education and employment, and where they lived. The study was recently published in the European Heart Journal. (ANI) APRIL 2013 ISSUE REAL ESTATE SPECIAL TO SEE YOUR AD IN PRINT - CALL BECOME A PART OF SOCIAL 206-501-2254 SUPPORT SYSTEM IN Sacramento 281-381-0744 We need volunteers Email your contributions to: [email protected] 1-888-622-0941 .DESISS. www Seattle South Asian |March 2013 org [email protected] EASTER (Contined From Page 11) In many languages, the words for “Easter” and “Passover” are etymologically related or homonymous. Easter customs vary across the Christian world, but attending sunrise services, exclaiming the Paschal greeting, clipping the church and decorating Easter eggs, a symbol of the empty tomb, are common motifs. Additional customs include egg hunting, the Easter Bunny, and Easter parades, which are observed by both Christians and some non-Christians. Page 13 Seattle South Asian |March 2013 Page 14 Seattle South Asian |March 2013 Page 14 Seattle South Asian |March 2013 Page 15 Community Calendar MARCH 2013 Community Calendar We have compiled this event listing based on the information available on the web site (where ever possible) of the community/organization as of third Friday. Please check with the organizers to confirm its accuracy. We request all South Asian organizations to email us ([email protected]) their community calendar on or before 20th of every month, for the events happening next month. We will carry listing of all South Asian non-profit organizations in Seattle. If the Name, Contact info is not correct or has changed email us the changes you want to see. E&OE. Schedule: 11:00 AM - 03:00 PM, March 16, Saturday, 08:30 AM - 09:30 AM, Holi celebration is at Rotunda Picnic Shelter, Lake Sammamish State Park, 2000 NW Sammamish Road, Issaquah, WA. For more information, contact Ashish Soni at 425-301-2255 or email at ash_ [email protected] Free Meditation Session - Isha Kriya at HTCC, 3818 212th St SE , Bothell, WA . March 30, Saturday, HOLI (Continued From Page 01) He demanded that people stop worshipping Gods and start praising respectfully to him. Hiranyakashipu, on the lap, being ordered young Prahlada to sit on a pyre in the lap of Holika, Hiranyakashipu’s demoness sister, who also could not die because she had a boon preventing her from being burned by fire. How Insects Find ‘Mr. Right’ Washington, February 14 (ANI): It may be difficult for you to find your perfect mate, but for one wasp species, it only takes a whiff of his special love potion to know whether he’s “Mr. Right.” mones, then how did the vast array of these scents evolve in insects? They found that the pheromones of all known Nasonia wasps con- mone, so that it resembled that of the other species,” said Josh Gibson, an ASU doctoral student working with Jürgen Gadau, a professor in School of Life Sciences in the College of Liberal Arts and Sciences. Female N. vitripennis wasps did not respond when offered the new pheromone alone. Unlike humans, most insects rely on their sense of smell when looking for a mate. Scientists have found that sex pheromones play an important role in finding a suitable partner of the same species; yet, little is known about the evolution and genetic basis of these alluring smells. They responded only when it was combined with the two original, or ancestral, scents. In addition, females from a closely related species, Nasonia giraulti, did not distinguish between the new and ancestral sex pheromones, regardless of whether there were two or three scents. A team of researchers from Arizona State University and Germany found that one wasp species has evolved a specific scent, or pheromone, which keeps it from mating with other species. killed by Narasimha, an incarnation of Vishnu. According to this belief, Hiranyakashipu’s own son, Prahlada, was a devotee of Lord Vishnu. In spite of several threats from Hiranyakashipu, Prahlada continued offering prayers to Lord Vishnu. He was poisoned by Hiranyakashipu, but the poison turned to nectar in his mouth. He was ordered to be trampled by elephants yet remained unharmed. He was put in a room with hungry, poisonous snakes and survived. All of Hiranyakashipu’s attempts to kill his son failed. Finally, he Prahlada readily accepted his father’s orders, and prayed to Lord Vishnu to keep him safe. When the fire started, everyone watched in amazement as Holika burnt to death, while Prahlada survived unharmed. The salvation of Prahlada and burning of Holika is celebrated as Holi. The ritual of witch burning is also present in other spring festivals, like Walpurgis Night. In Mathura, where Lord Krishna grew up, the festival is celebrated for 16 days (until Rangpanchmi) in commemoration of the divine love of Radha for Krishna. The festivities officially usher in spring, the celebrated season of love. Seattle South Asian |March 2013 In addition, they discovered that the genetic basis of the new scent is simple, which allows the males to change an existing scent into a new one. Over time, the females recognize and use this new scent to distinguish their own species from others. Scientists from ASU, the University of Regensburg, the Zoological Research Museum Alexander Koenig Bonn, and the Technical University Darmstadt in Germany, studied two species of the parasitic wasp genus Nasonia to learn about the evolution of sex pheromones. They asked, if male sex pheromones are used as unique mating signals to attract females, and if female wasps will not mate with males that have different phero- tain two elements except for one species, Nasonia vitripennis, which uses a novel third ingredient. These tiny wasps, less than half the size of a grain of rice, lay their eggs in developing flies. The two species in this study prefer laying their eggs in similar types of flies and are found in the same parts of the Eastern United States, which means they have many opportunities to choose the wrong mate. “We identified a gene in N. vitripennis that we thought was responsible for its unique scent. Then, we successfully conducted an experiment to suppress that gene, which actually changed the composition of the sex phero- first evolved. Thus, the researchers concluded that the N. vitripennis females did not react to the third component when it Instead, they adapted to the new smell over time and now it is an integral part of the species-specific sex pheromone of N. vitripennis males. This study is one of the few where researchers have identified genes that prevent a species from breeding with another closely related species. The findings provide new insights into the evolution of genes that contribute to speciation, or the formation of new species, as well as the evolution of diverse sex pheromones. Scientists presented their findings in an article published online in the journal Nature. (ANI) Page 15 Seattle South Asian |March 2013 Page 16 Human Heart Develops Slower Than Other Mammals Washington, February 22 (ANI): Researchers have created the first comprehensive model of human heart development using observations of living foetal hearts. The results showed surprising differences from existing animal models. Although scientists saw four clearly defined chambers in the foetal heart from the eighth week of pregnancy, they did not find organised muscle tissue until the 20th week much later than expected. Developing an accurate, computerised simulation of the foetal heart is critical to understanding normal heart development in the womb and, eventually, to opening new ways of detecting and dealing with some functional abnormalities early in pregnancy. Studies of early heart development have previously been largely based on other mammals such as mice or pigs, adult hearts and dead human samples. The research team, led by scientists at the University of Leeds is using scans of healthy foetuses in the womb, including one mother who volunteered to have detailed weekly ECG (electrocardiography) scans from 18 weeks until just before delivery. This functional data is incorporated into a 3D computerised model built up using information about the structure, shape and size of the different components of the heart from two types of MRI (Magnetic Resonance Imaging) scans of foetuses’ hearts. Early results are already suggesting that the human heart may develop on a different timeline from other mammals. While the tissue in the walls of a pig heart develops a highly organised structure at a relatively early stage of a foetus’s development, the researchers found that there is little organisation of the human heart’s cells until 20 weeks into pregnancy. A pig’s pregnancy lasts about three months and the organised structure of the walls of the heart emerge in the first month of pregnancy. The new study only detected similar organised structures well into the second trimester of the human pregnancy. Human foetuses have a regular heartbeat from about 22 days. Dr Eleftheria Pervolaraki, Visiting Research Fellow at the University of Leeds’ School of Biomedical Sciences, said: “For a heart to be beating effectively, we thought you needed a smoothly changing orientation of the muscle cells through the walls of the heart chambers. Such an organisation is seen in the hearts of all healthy adult mammals. “Foetal hearts in other mammals such as pigs, which we have been using as models, show such an organisation even early in gestation, with a smooth change in cell orientation going through the heart wall. But what we actually found is that such organisation was not detectable in the human foetus before 20 weeks,” she said. Professor Arun Holden, also from Leeds’ School of Biomedical Sciences, added: “The development of the foetal human heart is on a totally different timeline, a slower timeline, from the model that was being used before. “This upsets our assumptions and raises new questions. Since the wall of the heart is structurally disorganised, we might expect to find arrhythmias, which are a bad sign in an adult. “It may well be that in the early stages of development of the heart arrhythmias are not necessarily pathological and that there is no need to panic if we find them. Alternatively, we could find that the disorganisation in the tissue does not actually lead to arrhythmia,” Holden added. The research was conducted by a team including academics from the University of Sheffield, University of Leeds, the University of Edinburgh, the University of Nottingham, and the University of Manchester. The finding has been published in the Journal of the Royal Society Interface Focus. (ANI) Milky Way Grew By ‘Cannibalizing’ Other Smaller Galaxies Washington, February 22 (ANI): NASA’s Hubble Space Telescope peered deep into the vast stellar halo that envelops our Milky Way galaxy and uncovered tantalizing evidence for the possible existence of a shell of stars that are a relic of cannibalism by our Milky Way. scope Science Institute (STScI) in Baltimore, Md. They also offer a new opportunity for measuring the “hidden” mass of our galaxy, which is in the form of dark matter (an invisible form of matter that does not emit or reflect radiation). Hubble was used to precisely measure, for the first time ever, the sideways motions of a small sample of stars located far from the galaxy’s center. In a universe full of 100 billion galaxies, our Milky Way “home” offers the closest and therefore best site for detailed study of the history and architecture of a galaxy. Their unusual lateral motion is circumstantial evidence that the stars may be the remnants of a shredded galaxy that was gravitationally ripped apart by the Milky Way billions of years ago. A team of astronomers led by Alis Deason of the University of California, Santa Cruz, and van der Marel identified 13 stars located roughly 80,000 light-years from the galaxy’s center. These stars support the idea that the Milky Way grew, in part, through the accretion of smaller galaxies. They lie in the Milky Way’s outer halo of ancient stars that date back to the formation of our galaxy. “Hubble’s unique capabilities are allowing astronomers to uncover clues to the galaxy’s remote past. The more distant regions of the galaxy have evolved more slowly than the inner sections. Objects in the outer regions still bear the signatures of events that happened long ago,” said Roeland van der Marel of the Space Tele- The team was surprised to find that the stars showed more of a sideways, or tangential, amount of motion than they expected. This movement is different from what astronomers know about the halo stars near the Sun, which move predominantly in radial orbits. Deason and her team plucked the outer halo stars out of seven Seattle South Asian |March 2013 years’ worth of archival Hubble telescope observations of our neighboring Andromeda galaxy. In those observations, Hubble peered through the Milky Way’s halo to study the Andromeda stars, which are more than 20 times farther away. The astronomers identified the stars based on their colors, brightnesses, and sideways motions. The halo stars appear to move faster than the Andromeda stars because they are so much closer. Team member Sangmo Tony Sohn of STScI identified the halo stars and measured both the amount and direction of their slight sideways motion. The stars move on the sky only about one milliarcsecond a year, which would be like watching a golf ball on the Moon moving one foot per month. Nonetheless, this was measured with 5 percent precision, made possible in visible-light observations because of Hubble’s razorsharp view and instrument consistency. Stars in the inner halo have highly radial orbits. When the team compared the tangential motion of the outer halo stars with their radial motion, they were very surprised to find that the two were equal. Computer simulations of galaxy formation normally show an increasing tendency towards radial motion if one moves further out in the halo. These observations imply the opposite trend. The existence of a shell structure in the Milky Way halo is one plausible explanation of the researchers’ findings. Such a shell can form by accretion of a satellite galaxy. This is consistent with a picture in which the Milky Way has undergone continuing evolution over its lifetime due to the accretion of satellite galaxies. The team compared their results with data of halo stars recorded in the Sloan Digital Sky Survey. Those observations uncovered a higher density of stars at about the same distance as the 13 outer halo stars in their Hubble study. A similar excess of halo stars exists across the Triangulum and Andromeda constellations. Beyond that radius, the number of stars plummets. Deason immediately thought the two results were more than just coincidence. “What may be happening is that the stars are moving quite slowly because they are at the apocenter, the farthest point in their orbit about the hub of our Milky Way. The slowdown creates a pileup of stars as they loop around in their path and travel back towards the galaxy. So their in and out or radial motion decreases compared with their sideways or tangential motion,” Deason explained. Shells of stars have been seen in the halos of some galaxies, and astronomers predicted that the Milky Way may contain them, too. But until now there was limited evidence for their existence. The halo stars in our galaxy are hard to see because they are dim and spread across the sky. Encouraged by this study, the team hopes to search for more distant halo stars in the Hubble archive. The Hubble study will appear in an upcoming issue of the Astrophysical Journal. (ANI) Page 16 Seattle South Asian |March 2013 Page 17 Kids With TV Addiction Likelier To Commit Crime Washington, February 19 (ANI): Children and adolescents who watch a lot of television are more likely to exhibit antisocial and criminal behaviour as adults, according to a new research from New Zealand. The study by the University of Otago followed a group of around 1000 children born in the New Zealand city of Dunedin in 197273. Every two years between the ages of 5 and 15, they were asked how much television they watched. Those who watched more televi- Study co-author Associate Professor Bob Hancox of the Uni- The study also found that watching more television in childhood was associated, in adulthood, with aggressive personality traits, an increased tendency to experience negative emotions, and an increased risk of antisocial personality disorder; a psychiatric disorder characterised by persistent patterns of aggressive and antisocial behaviour. A study co-author, Lindsay Robertson, says it is not that chil- sion were more likely to have a criminal conviction and were also more likely to have antisocial personality traits in adulthood. versity’’s Department of Preventive and Social Medicine says he and colleagues found that the risk of having a criminal conviction by early adulthood increased by Stem Cell-Based Bioartificial Tissues And Organs Being Developed Washington, February 19 (ANI) other fields, such as neurology. A bioengineered stem cell-based trachea, composed of both artificial and biological material, has been successfully transplanted. The aim is to make as much use of the body’’s own healing potential as we can”, said Macchiarini, Professor of Regenerative Surgery at Karolinska Institutet, and responsible for the surgery. Surgeon Paolo Macchiarini who conducted the transplant is now planning to use the technique to recreate more complex tissues, such as the oesophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. In June 2011, media all over the world reported about a ground breaking transplant, where a patient received an artificial trachea covered in his own stem cells. The result was an artificial windpipe with biological functions. To date, five operations have been carried out using this technique. “We learn something from each operation. This means we can develop and refine the technique. We are also evaluating how we can transfer our experiences to about 30 percent with every hour that children spent watching TV on an average weeknight. Using the technology, they also plan to operate a 2 year-old girl in the USA in March. The girl was born without a trachea and has lived her entire life in intensive care, where she breathes through a tube placed in the oesophagus and connected directly to the lungs. Without a new trachea, she will never be able to leave the hospital. This will be the first time the procedure is conducted on a small child. In experimental trials on rats, the research team has investigated the possibility to replace brain matter that has been damaged by serious trauma sustained from events such as traffic accidents, gunshot wounds or surgery. The aim is to replace the lost brain matter with a cultivated stem cell based substance and in turn, avoid neurological damage. The experimental attempt that has been conducted on rats and mice has shown positive results. On two occasions, severely injured patients with acute refractory lung failure received stem cell based therapy showing immediate functional improvement. It is also the first time the procedure will be conducted on an individual without a trachea - as previously, diseased organs have been replaced. Although both patients died as a consequence of multi-organ failure, the result has provided the first evidence that stem cell therapy can be a promising alternative to restore function in certain damaged organs - without the need for them to be removed and replaced with healthy donor organs. There are also plans to transplant the oesophagus, an organ that is more complex than a trachea as it has muscles. Macchiarini will be presenting his work during his seminar at the scientific AAAS Annual Meeting in Boston. (ANI) Seattle South Asian |March 2013 dren who were already antisocial watched more television. “Rather, children who watched a lot of television were likely to go on to manifest antisocial behaviour and personality traits.” While we’’re not saying that television causes all antisocial behaviour, our findings do suggest that reducing TV viewing could go some way towards reducing rates of antisocial behaviour in society,” says Associate Professor Hancox. The study has been published online in the US journal Pediatrics. (ANI) Patients’ Own Bone Marrow Cells Used In Bladder Regeneration Washington, February 19 (ANI): An Indian origin scientist and his team have taken a new approach to bladder regeneration by harvesting cells from a patient’’s healthy bone marrow. The Northwestern Medicine research, by lead author Arun K. Sharma, research assistant professor in urology at Northwestern University Feinberg School of Medicine and colleagues, is an alternative to contemporary tissueengineering strategies. The bone marrow cells are being used to recreate the organ’’s smooth muscle, vasculature, and nerve tissue. “We are manipulating a person’’s own disease-free cells for bladder tissue reformation,” said Sharma, a member of the Institute for BioNanotechnology in Medicine and the Ann and Robert H. Lurie Children’’s Hospital of Chicago Research Center. “We have used the spina bifida patient population as a proof of concept model because those patients typically have bladder dysfunction. However, this regeneration approach could be used for people suffering from a variety of bladder issues where the bone marrow microenvironment is deemed normal,” they said. In end-stage neurogenic bladder disease – an illness often associated with spinal cord diseases like spina bifida – the nerves which carry messages between the bladder and the brain do not work properly, causing an inability to pass urine. The most common surgical option, augmentation cystoplasty, involves placing a “patch” derived from an individual’’s bowel over a part of the diseased organ in order to increase its size. The current “gold standard,” the procedure remains problematic because the bowel tissue introduces long-term complications like the development of electrolyte imbalance and bladder cancer. Because Sharma’’s procedure does not use bowel tissue, it offers the benefits of augmentation without the association of longterm risks. His technique combines stem and progenitor cells from a patient’’s bone marrow with a synthetic scaffold created in the lab of Guillermo Ameer, ScD, professor of biomedical engineering at McCormick School of Engineering and Applied Science and of surgery at Feinberg. The scaffold takes the place of the traditional patch. “We decided to use material that has the ability to be tailored to simulate mechanical properties of the bladder,” said Sharma, director of pediatric urological regenerative medicine at Lurie Children’’s. “Using the elastomer created by Dr. Ameer and the bone marrow stem and progenitor cells, I believe that we have developed a technique that can potentially be used in lieu of current bladder augmentation procedures. However, further study is needed,” he concluded. The research will be published in the Proceedings of the National Academy of Sciences. (ANI) Page 17 Seattle South Asian |March 2013 Star With Cool Atmospheric Layer Similar To That Of Sun Identified Washington, Feb 20 (ANI): ESA’s Herschel space observatory has detected a cool layer in the atmosphere of Alpha Centauri A, the first time this has been seen in a star beyond our own Sun. The finding is not only important for understanding the Sun’s activity, but could also help in the quest to discover proto-planetary systems around other stars. The Sun’s nearest neighbours are the three stars of the Alpha Centauri system. The faint red dwarf, Proxima Centauri, is nearest at just 4.24 light-years, with the tight double star, Alpha Centauri AB, slightly further away at 4.37 light-years. Alpha Centauri B has recently been in the news after the discovery of an Earth-mass planet in orbit around it. But Alpha Centauri A is also very important to astronomers: almost a twin to the Sun in mass, temper- Seattle South Asian Editor: Bala Kumar Operations: Ram Ramaswamy Jyothi K. Mariswaran Manimekalai Marketing: Aparna Radhakrishnan Jayachitra Vijay Publisher:Vidya Kumar Design/Layout /Marketing/Distribution: Palepages llc Tel: 206-501-2254 Fax: 512-685-2324 [email protected] ©All rights reserved. ature, chemical composition and age, it provides an ideal natural laboratory to compare other characteristics of the two stars. One of the great curiosities in solar science is that the Sun’s wispy outer atmosphere – the corona – is heated to millions of degrees while the visible surface of the Sun is ‘only’ about 6000ºC. Even stranger, there is a temperature minimum of about 4000ºC between the two layers, just a few hundred kilometres above the visible surface in the part of Sun’s atmosphere called the chromosphere. Both layers can be seen during a total solar eclipse, when the Moon briefly blocks the bright face of the Sun: the chromosphere is a pink-red ring around the Sun, while the ghostly white plasma streamers of the corona extend out millions of kilometres. The heating of the Sun’s atmosphere has been a conundrum for many years, but is likely to be related to the twisting and snapping of magnetic field lines sending energy rippling through the atmosphere and out into space – possibly in the direction of Earth – as solar storms. Why there is a temperature minimum has also long been of interest to solar scientists. Now, by observing Alpha Centauri A in far-infrared light with Herschel and comparing the results with computer models of stellar atmospheres, scientists have made the first discovery of an equivalent cool layer in the atmosphere of another star. “The study of these structures has been limited to the Sun until now, but we clearly see the signature of a similar temperature inversion layer at Alpha Centauri A,” Rene Liseau of the Onsala Space Observatory, Sweden, and lead author of the paper presenting the results said. “Detailed observations of this kind for a variety of stars might help us decipher the origin of such layers and the overall atmospheric heating puzzle,” Liseau said. Understanding the temperature structure of stellar atmospheres may also help to determine the presence of dusty planet-forming discs around other stars like the Sun. (ANI) Seattle South Asian |March 2013 Page 18 Coffee During Pregnancy Could Harm Unborn Babies London, February 19 (ANI): Pregnant women should avoid drinking coffee because even a single cup of it a day could h a r m their unborn babies, r e searchers have warned. T h e y r e ported in the journal B M C Medic i n e that caffeine content is linked to low birth weight and prolonged pregnancies, according to the Daily Express. The researchers used information They found that caffeine reduced birth weight by 21g to 28g per 100mg consumed a day by mothers. Caffeine from all sources also increased the length of the pregnancy by five hours per 100mg a day. about almost 60,000 pregnancies over 10 years. (ANI) But caffeine intake specifically from coffee was associated with eight hours extra for every 100mg per day consumed. Secret Code Used To Bury Bad News In Bible Uncovered London, February 22 (ANI): Using a new tool, researchers have uncovered a secret code used in Bible to sandwich bad news between good news. The opening and closing verses of the book contain frequent mentions of life, whereas mentions of death are only found in clusters in the middle, the researchers said. The text-analysis tool, called Search Visualizer, represents entire texts as a grid with each square representing a word and coloured squares representing search keywords. The new pattern emerged when used to examine the words ‘’life’’ and ‘’death’’ in the King James Version of Genesis, the Daily Mail reported. The team at Keele University, UK, and Amridge University, USA, noted that the discovery is the first known use of a technique known as ‘bracketing’, which sandwiches one theme between two mentions of another theme. The technique is commonly used today. Dubbed the ‘’Genesis Death Sandwich’’, this pattern offers the first clear example of this common rhetorical structure being used in the text describing the creation of the universe. “This is a significant discovery for historians and theologians interested in the Old Testament, and shows that whoever wrote the version of the text that has been passed down to us was clearly employing this rhetorical structure,” said Dr Gordon Rugg of Keele University, who developed a new tool for analysing texts. Though the team are not sure if the placement was done on purpose, they believe that the pattern was used to soften the negative messages of death, or perhaps to juxtapose life and death for greater impact. Dr Gordon Rugg from Keele University and Dr David Musgrave from Amridge University, USA, have also used Search Visualizer to explore other significant texts including the Iliad. They have uncovered a pattern in the text that provides new evidence supporting a theory that one section, ‘The Catalogue of Ships’, is in fact an older poem incorporated into Homer’s epic story. Apart from exploring patterns in historical texts and literature, the new tool has a wide range of other potential applications. It may be used to re-examine cold-case police investigations by analysing old witness statements to identify correlating stories. The software can also be used as a new way of searching the web. (ANI) Page 18 Seattle South Asian |March 2013 Page 19 ‘Happily’ Married Couples Healthier Than Unmarried Peers Washington, February 14 (ANI): Married people have better mental and physical health than their unmarried peers and are less likely to develop chronic conditions than their widowed or divorced counterparts, according to a new study. A University of Missouri expert said that people who have happy marriages are more likely to rate their health as better as they age; aging adults whose physical health is declining could especially benefit from improving their marriages. Christine Proulx, an assistant professor in the MU Department of Human Development and Family Studies, examined the long-term relationship between self-rated health and marital quality. She found that, in all stages of marriage, positive or negative relationships affect the individuals’ health. Spouses should be aware that how they treat each other and how happy they are in their marriages affect both partners’ health, and they should think more about their personal relationships when thinking holistically about their health, she said. “We often think about the aging process as something we can treat medically with a pill or more exercise, but working on your marriage also might benefit your health as you age,” Proulx said. “Engaging with your spouse is not going to cure cancer, but building stronger relationships can improve both people’s spirits and well-being and lower their stress,” she noted. Proulx suggested that health professionals consider patients’ personal relationships when designing health promotion programs or treatment plans. Proulx analyzed data from 707 continuously married adults who participated in the Marital Instability Over the Life Course panel study, a 20-year, nationwide research project started in 1980 with funding from the Social Security Administration’s Office of Research and Statistics and the National Institute on Aging. Most study participants were Caucasian, had more than high school educations, and earned more than 55,000 dollars in annual family income in 2000. Because of these characteristics, Proulx said that the participants probably had some protection against marital and health challenges more commonly faced by people of different ethnicities or with less education or income. The study will be published in the upcoming issue of the Journal of Family Psychology. (ANI) New Potential Drug Target For Cancer Identified Washington, February 14 (ANI): Scientists have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development. Additionally, the international team led by scientists at The University of Texas MD Anderson Cancer Center found the cancer drug sunitinib potentially has a new role in treating triple-negative, claudin-low breast cancer, a particularly resistant version of a type of cancer that is already difficult to treat. “We found that FOXC2 lies at the crossroads of the cellular properties of cancer stem cells and cells that have undergone epithelial to mesenchymal transition (EMT), a process of cellular change associated with generating cancer stem cells,” said senior author Sendurai Mani, Ph.D., assistant professor in MD Anderson’s Department of Translational Molecular Pathology and co-director of the Metastasis Research Center. Cancer stem cells are fewer in number than other tumor cells, yet research has tied them to cancer progression and resistance to treatment. Abnormal activation of the epithelial to mesenchymal transition can create cancer stem cells, Mani noted. “There are multiple molecular pathways that activate EMT. We found many of these pathways also activate FOXC2 expression to launch this transition, making FOXC2 a potentially efficient check point to block EMT from occurring,” Mani said. Research uncovering this connection focused on cell line and mouse model experiments. The next important step will be to assess the expression and activity of FOXC2 in human tumor samples, he said. In the meantime, sunitinib, known commercially as Sutent and approved by the U.S. Food and Drug Administration for three other cancers, provides interesting, more immediate, potential. “FOXC2 is a transcription factor, a protein that binds to DNA in the promoter region of genes to activate them. For a variety of reasons, tran- Seattle South Asian |March 2013 scription factors are hard to target with drugs,” Mani said. The team found that FOXC2 also regulates the platelet derived growth factor receptor (PDGFR-Beta). In cancer cell lines, they found that the PDGFR-Beta inhibitor sunitinib inhibited growth of cells with EMT or cancer stem cell properties that have active FOXC2. Mice with triple-negative breast cancer treated with sunitinib had smaller primary tumors, longer survival, and fewer incidences of metastasis. There also was a steep drop in the cells’ ability to form mammospheres, a hallmark of cancer stem cells. Mani said the team believes that targeting FOXC2 pathway using either PDGFR-beta inhibitors or other yet-to-be-known smallmolecule inhibitors will be an effective therapeutic strategy for inhibiting EMT and consequently reducing EMT/cancer stem cellassociated metastasis, relapse and therapy resistance. The study has been published in the journal Cancer Research. (ANI) Men With Wider, Shorter Faces Likelier To Make Racist Remarks Washington, February 14 (ANI): The structure of a man’s face may indicate his tendency to express racially prejudiced beliefs, according to a new research. Studies have shown that facial width-to-height ratio (fWHR) is associated with testosteronerelated behaviors, which some researchers have linked with aggression. But psychological scientist Eric Hehman of Dartmouth College and colleagues at the University of Delaware speculated that these behaviors might have more to do with social dominance than outright aggression. The researchers decided to examine the relationship between fWHR and dominance in the specific context of racial prejudice. They asked male participants about their willingness to express racially prejudiced beliefs and about the pressure they feel to adhere to societal norms. The results revealed that men who have higher fWHR (determined from photos of their faces) are more likely to express racist remarks and are less concerned about how others perceive those remarks. Importantly, these results did not show that the men were necessarily more prejudiced — men with greater fWHR did not score higher on measures that assessed implicit, or more automatic, racial prejudice. Rather, these men were simply more likely to express any prejudicial beliefs they may have had. “Not all people with greater fWHRs are prejudiced, and not all those with smaller fWHRs are non-prejudiced. You could think about it as a ‘side effect’ of social dominance — men with greater fWHR may not care as much about what others think of them,” noted Hehman. Results from a second study suggest that observers actually perceive and use fWHR when evaluating another person’s degree of prejudice. Looking at the photos from the first study, a new group of participants evaluated men with wider, shorter faces as more prejudiced, and they were able to accurately estimate the target’s self-reported prejudicial beliefs just by looking at an image of his face. The results were confirmed in a third study. The third study also showed that non-White participants, whose outcomes are more likely to be influenced by their race or ethnicity, were more motivated to accurately assess targets’ prejudice. This greater motivation, in turn, was associated with increased accuracy. The finding is consistent with the idea that people allocate their attention to stimuli that can influence their outcomes. Together, these three studies add to a growing literature exploring how people perceive and accurately infer personality characteristics based on physical appearance. “This research provides the first evidence for a facial metric that not only predicts important and controversial social behaviors, such as reporting prejudices, but can also be used by others to make accurate judgments,” said Hehman. These studies may open up new avenues of research; Hehman and colleagues speculate that fWHR may be linked with explicit prejudice on a number of different dimensions beyond race. The study was published in Psychological Science, a journal of the Association for Psychological Science. (ANI) Page 19 Seattle South Asian |March 2013 Page 20 Heavy Internet Users Can Have Withdrawal Symptoms Like Drug Abusers London, February 18 (ANI) Using the internet for long periods of time can cause withdrawal symptoms similar to the ‘comedown’ experienced by drug users, scientists have warned. tests to find out their level of ad- they were depressed. Using the internet had a ‘striking’ impact on the positive mood of those who were addicted to the web, and their comedown was far more pronounced than those who used it less often, the research noted. Researchers found that spending excessive periods of time surfing the internet left people in ‘negative moods’ and, like drug addicts, when heavy internet users go back on the web their negative moods lift, the Daily Mail reported. And these withdrawal symptoms may promote a vicious cycle. “The immediate negative impact of exposure to the internet on the mood of internet addicts may contribute to increased usage by those individuals attempting to reduce their low mood by reengaging rapidly in internet use,” the study said. Our results show that around half of the young people we studied spend so much time on the net that it has negative consequences for the rest of their lives, said Professor Phil Reed, from the university’s psychology department. The study, published in the international journal Plus One, was carried out on 60 volunteers with an average age of 25 at Swansea University’s College of Human and Health Sciences. The researchers first gave volunteers a series of psychological Early Humans Turned Their Hairless Skin Into Canvases To Look Attractive Washington, February 18 (ANI): About 1.5 to 2 million years ago, early humans, who were regularly on the move as hunters and scavengers, evolved into nearly hairless creatures to more efficiently sweat away excess body heat, but later they began to decorate skin to increase attractiveness to the opposite sex and to express, among other things, group identity, according to a Penn State anthropologist. Over the millennia, people turned their skin into canvases of selfexpression in different ways, including permanent methods, such as tattooing and branding, as well as temporary ones, including cosmetics and body painting, according to the researcher, said Nina Jablonski, Distinguished Professor of Anthropolog. Jablonski said both males and females use forms of skin decoration to become more attractive to the opposite sex. Women, for example, may use makeup to increase the size of were tested again for mood and levels of anxiety. their eyes, a cue that is considered attractive in most cultures. Males in some cultures also use skin decoration as a way to bring out facial features to appeal to women, or to look more menacing and warrior-like. diction to the internet, their mood, their anxiety level and whether They were told to browse the internet for 15 minutes, then they Long, Low Intensity Exercise More Beneficial Than Short, Intense Workouts Washington, February 14 (ANI): When the amount of calories ned is the same, standing and walking for longer stretches could actually structed to sit for 14 hours each day and not indulge in any form of exercise; the second regime required participants to sit for 13 hours each day and exercise Jablonski said that she and other researchers based their estimate on when humans evolved hairless skin on the study of the fossil record and an examination of the molecular history of genes that code proteins that help produce skin pigmentation. “We find a lot of evidence of when humans began to lose hair based on molecular genetics,” said Jablonski. While it is difficult to exactly say when humans began to decorate their skin, Jablonski said that some of the earliest preserved skin shows signs of tattooing. Jablonski presented her finding at the annual meeting of the American Association for the Advancement of Science in Boston. (ANI) Seattle South Asian |March 2013 The negative impact of excessive internet use can be seen across a wide range of aspects of the addict’s life. Internet addiction was associated with long-standing depression, impulsive non-conformity, and autism traits, it concluded. (ANI) be better than high intensity exercise in improving cholesterol and preventing diabetes, researchers suggest. vigorously for 1 hour; and in the third, participants substituted six hours of sitting with four of walking and two hours standing. Hans Savelberg and colleagues from Maastricht University, therlands recruited eighteen normalweight 19 to 24-year-old participants for their study and asked them to follow three regimes. After each regime, the researchers tracked each participant’’s insulin sensitivity and blood lipid levels, both of which can help identify metabolic conditions like diabetes and obesity. In the first, participants were in- The authors found that overall, when participants followed the strictly sedentary regimen they burned over the course of the day than in the other two routines, which were roughly the same. Cholesterol and lipid levels improved slightly when participants exercised vigorously for an hour each day, but improved significantly when participants were active for longer periods at low intensity According to the study, being active simply by standing or walking for long periods of time significantly improved insulin levels compared to both a strictly sedentary lifestyle, and one in which participants were largely sedentary except for an hour of exercise each day. The study concludes that when energy expenditure is equivalent, longer durations of low-intensity exercise may offer more benefits than shorter periods of intense activity. The study was recently published in the open access journal PLOS ONE. (ANI) Page 20 Seattle South Asian |March 2013 Page 21 CHECK YOUR SIGN By Pandit Parashar ARIES (March 21 to April 20): Planets are gathered in house of gains to help you out this month. Some of you will will be making a smooth switch to another job. Its high time to ask the boss for a raise long overdue but only in first two weeks other wise it will be too late. You have good chances of hooking up with some one from different culture. TAURUS (April 21 to May 20): You will continue to get help from people in power till March 15th. With a cool and calm mind you will be able to resolve an issue involving a property in dispute. Time in second half will bring many positive changes in life. You will make some useful contacts and people in business will sign a few important contracts. GEMINI (May 21 to June 20): You will successfully launch a big project you had been working on for quite some time in second half of March. New strategy will be helpful in reducing financial pressure. You will start working on a travel plan. Children will be a source of happiness. You will become more popular and gain new business this month. Bank balance will grow too. CANCER (June 21 to July 22): Combination of Sun, Mars and Venus in house of luck after march 15th is very helpful. So if possible delay your career and finances related matters till then. Things will be kind of slow in first two weeks and you may face obstacles. You should hit some kind of financial jackpot in second half of march. LEO (July 23 to August 22): You will accomplish a lot in first half of March. This could be the right time to seek favors from government officials or the boss. Some one close will make unreasonable demand and try to take undue advantage of your generosity in second half of March. You will benefit from some one lot younger in age. VIRGO (August 23 to September 22): You will benefit from a person from totally different culture. Do not hesitate to grab the opportunity. You may be making a very sound investment in second half. Pay attention to the legal papers you receive this month and have proper advice before you reply. You will be called for second interview this month. LIBRA (September 23 to October 22): It will be in your best interest not to make any big financial commitments this month. People in business will spend more money on advertising. It is another favorable month for job seekers or those looking for a change closer to home. Chances of an addition in the family are very strong during the month. SCORPIO (October 23 to November 22): Another fruitful month for you. Confidence level will be on the peak as you will keep hitting the bulls eye. For people in jobs a big promotion on hold for past few months will become a reality in second half. Its good to be ambitious but within legal pa- High-Fibre Foods Contain More Calories Than Labels Suggests London, February 19 (ANI): Some high-fibre foods, which are sold as low in calories, may actually contain, in the extreme, up to 25 per cent more calories than the label suggests, nutritional experts have said. It means that some high-fibre foods targeted at people on a diet are actually more fattening than people are led to believe, said Geoffrey Livesey, an independent nutritionist based in Britain who has advised the UN’s Food and Agriculture Organisation. Dr Livesey told the American Association for the Advancement of Science meeting in Boston that consumers have been unknowingly consuming extra calorie in high-fibre food for decades be- cause the system for assessing calories goes back to the 1970s and even earlier, according to the Independent. It means that if people follow the daily recommended intake of 18 grams of fibre, they could be consuming more than 250 extra calories each week without realising it, he said. Food manufacturers and government agencies have consistently misled consumers over many years about the number of calories contained in food, said experts. Government assessments about the amount of energy in food assume that the caloric value is the same whether the food it cooked or raw, but scientists know that Seattle South Asian |March 2013 raw food provides fewer calories because the body expends energy breaking it down, said Richard Wrangham of Harvard University. “There is a lot of misinformation around calories, and it is crucial for the consumer, whether they are on a diet or not, to have the correct information about what they eat,” he told the meeting. (ANI) MEN CAN COOK Email your recipe with your photos [email protected] rameters. You will spend money on upgrading a property. SAGITTARIUS (November 23 to December 22): Addition in the family that took place recently will bring good luck and you will start to notice that. Your negotiations with a well reputed company will continue to move in right direction and the final commitment can come any time during march. You will make some very useful contacts at the get together. CAPRICORN (December 22 to January 19): You will finally have a sigh of relief as financial pressure will disappear in second half of March. Mind may still remain little uneasy because of past pressure. You may be working extra hours to meet the pressure of deadline. You may need to visit a court to obtain some important papers in march. AQUARIUS (January 20 to February 18): Expect some very favorable changes in career this month. Business will pick up all of a sudden and you will get few major accounts. Any journey you go on will bring instant rewards. You may also visit a holy place with family. Some one close will invite you to a party at their place. Bank balance will grow fast. PISCES (February 19 to March 20): Do not take any chance with government this month. New colleague will impress you but maintain a distance. You may spend money on upgrading your home or buy some nice furniture items. Children will need more money and time from you. It will be better to call a close friend and seek his opinion about new offer. Pandit Parashar [email protected] www.parashar.com 925-833-7170 Your Office Coffee Mug Could Be Carrying ‘Colonies Of Germs’ Washington, February 18 (ANI) Your office coffee mug you use for just about every beverage could cause you to fall ill, says an expert. People rarely take their office coffee mug home for washing and many times they scrub it at the office with sponges and brushes that have been used by everyone, making a home for bacteria. In fact, Charles Gerba, Ph.D., a professor of environmental microbiology at the University of Arizona, told Mens Health that twenty percent of mugs carry fecal bacteria, according to the Huffington Post. “Colonies of germs are living in your favorite cup,” he told the magazine. So, cleaning your office cup is very important, said Gerba. He suggests bringing your favorite cup home daily to be washed in a dishwasher on the hottest temperature possible. If you don’t have a dishwasher, then first fill the cup with hot water and put a teaspoon of baking soda in it, letting it sit overnight. And then, finally wash it in hot water as you normally would, said one user on Mamapedia. (ANI) Page 21 Seattle South Asian |March 2013 Riteish’s Balak Palak Coming Soon In 15 Indian Languages Bollywood actor Riteish Deshmukh’s debut production venture, Marathi film BALAK PA L A K , based on curiosity about sex among adolescents, has been wellreceived by the masses and critics alike. The film also swept away various awards at ‘Zee Gaurav awards’ as the film was nominated in 15 categories. Buoyed with the recent success of BALAK PALAK, the actor-turned-producer Riteish Deshmukh, a month ago even shared his plans to re- make the film in Hindi. But now, it seems, the actor is so driven with the overwhelming response Page 22 Nirav Shoots Vijay Yes, Nirav shoots Ilayathalapathy - ‘Thalaivaa’ is certainly a big time visual treat. Cinematographer Nirav Shah has been the toughest pillar for all of AL Vijay’s projects, right from ‘Kireedom’, excepting only ‘Poi Solla Poram’. Can we forget how satiating the visual treat was in Ilayathalapathy’s ‘Pokkiri’? Thanks to Nirav Shah who is known for his lighting sense; and in this flick, he that he is planning to put it on a larger scale by making it in 15 different Indian languages Mr.Pellikoduku all Digital in USA has adopted different lighting and different theme setting. colour scheme to go with each The team has recently screened a couple of songs in grandeur of Nirav. Fight sequence shot on the busy roads of Mumbai have also come out well. The team will be packing off to a foreign country by March. Simbu Sings For NTR’s Baadshah It seems Simbhu is trying his luck in Telugu. Not as an actor but as a singer. He has recently sung a power mix song ‘Jagada Jagada’ for the movie ‘Back Bench Student’. The latest news is that he has been rendering his voice for NTR and Srinu Vytla’s upcoming movie, Baadhshah. He has sung the song ‘Diamond girl’ in the movie. The movie has already creating buzz with Siddharth playing a special role and Navadeep playing the villain. Now the latest news adds some more flavour to it. Kajal Agarwal plays the female lead in the film and Thaman is the music director. The audio of the movie releases on March 10th and the film is set to release on April 5th. Bandla Ganesh Babu produces the film under Parameswara Arts banner. Full length comedy entertainer Mr.Pellikoduku is all set to release in overseas on March 1 st with premiere shows on Feb 28th. We are releasing this movie in about 50 screens all over USA which is one of the biggest release of Sunil movies with all digital for best possible upgraded audio and video experience. Digital content is being uploaded to Los Angeles Quebe office and best quality CRU drives will be shipped out to respective theaters on Mon/ Tue well in advance. Premiere shows will be screened in all the locations on Feb 28th at 8pm. Please keep checking for updated schedules and theaters list which will be published soon. Read South Asian Online News www. southasiannewspapers .com Seattle South Asian |March 2013 Krantiveera Sangolli Rayanna Completes 100 Days! Krantiveera Sangolli Rayanna, a biopic starring Darshan, Jayaprada and Nikita Thukral in lead roles, has completed 100 days. Directed by Naganna, the films received positive response and has also bagged a huge collections. There are reports that they are planning for a huge success meet to celebrate the 100 days completion. SEATTLE SOUTH ASIAN Page 22 Seattle South Asian |March 2013 I Me Aur Main I Me Aur Main is an upcoming Hindi film starring John Abraham who plays the role of Ishaan - a charismatic, good-looking music producer from Mumbai. He lives a sheltered existence, is the centre of his life, the apple of his mother’s (Zarina Wahib) eye, always protected by his elder sister Shivani (Mini Mathur) and stays at his girlfriend Anushka’s (Chitrangda Singh’s) house. He takes them all for granted! One day his life falls apart like a house of cards. At this point, his new neighbour Gauri (Prachi Desai) comes into his life and from her he learns the importance of relationships. He starts taking initiatives to- wards mending and maintaining his past relationships. Page 23 Santhanam Changes His Director! Everybody knows comedy rules Kollywood. And Santhanam is undoubtedly the most powerful comedy actor in the industry and calls the shots. He decides whether he should do a superstar film or who directs him! Ishaan begins to truly fall in love with Gauri. There comes a point when he has to make a choice between his love that made him Santhanam after turning producer with Kanna Laddu Thinna Aasaya is now remaking the Telugu super hit Maryada Raman. Now the latest we hear is that he has replaced its original director Kannan with his choice Srinath who did Muthirai It is said PVP Cinemas the original right holders in Telugu wanted to do the film on first copy basis with Santhanam who is also playing the hero in the film. Santhanam who is doing multiple projects wanted a director who will listen to him and also shoot at his convenience, hence he preferred Srinath. Bhappi Lahari Launches Karupampatti Audio a better person or being a better person by taking responsibility of the actions he has done in the past. Famous Bollywood music director Bhappi Lahiri launched the audio of Tamil film Karupampatti, in Chennai. Bhappi da also crooned a number called `Disco Naughty Naughty Raja..` in the film composed by Kannan. ate of Shankar and stars Ajmal, Aparna Bajpai and Archana play the lead characters. number `Disco Naughty Naughty Raja...` from the film which drew huge applause. Ajmal the Karupampatti is directed by Prabhu Raja Cholan, a former associ- Offended ‘Isaignani’ In the audio launch of Bharathiraja’s comeback, ‘Annakodiyum Kodiveeranum’, Ilayaraja was fired a magazine of questions, which the Isaignani is not quite happy about. “All the questions that were shot at me at the audio launch, should have been asked to me in person. Bharathiraja chose to ask me in public, for he cannot stand my answers had it been otherwise” says the old wise man. Questions like why Ilayaraja is reluctant in joining hands with Vairamuthu and the likes, has irked him. “Neither do I blow my trumpet, nor do I point fingers at others like is normally done in the society. Bharathiraja compelled me to turn up at the event and ended up insulting me. I shall choose to ignore it like I will consider a fool’s speech” says the angered musician. Seattle South Asian |March 2013 Trailer and two songs from the film were shown at the launch. Bappida as he is popularly known took over the audio launch in his inimitable style. He said he does not normally move around without bodyguards, but Chennai is a peaceful place and South has always been nice to him. Bappida sang the hero of Karupampatti too was present at the event, and he said that the film will be a milestone film for him. He has three different get ups for the film. Prabhu Raja Cholan, said that he was taking a risky approach with some aspects of the film. Page 23 Seattle South Asian |March 2013 Seattle South Asian |March 2013 Page 24 Page 24