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Purity Stabilized HCLO Our patented Nano-Technology electrolytic process enables production of Pure and Stable HCLO in a liquid carrier where all the most important parameters are balanced and optimized in order to obtain one of the best formulation in terms of Efficacy and Safety to maximize its disinfectant properties. The process Main characteristics pH lower than 3 Oxido Reductive Potential (ORP) higher than 1100 mV Conductivity lower than 1300 μS cm-1 17 O-NMR Line width lower than 50 MHz Free Chlorine between 40 and 70 ppm (as HCLO higher than 95%) New patented nano-process to produce pure and stable HCLO dissolved in safe water Main References Nanocoated Electrolysis APPEARANCE LIQUID Free Chlorine Assay (mg/l) Spectrophotometric Method 90.0 - 150.0 Total Chlorine Assay (mg/l) Spectrophotometric Method 90.0 - 150.0 Total Chlorine Assay (mg/l) Iodometric Method 90.0 - 150.0 Chlorites Assay (ug/l) EPA 300.1, 1997 (as ClO2) < 100 Chlorates Assay (mg/l) EPA 300.1, 1997 <1 pH (as is by Mettler Toledo pHmeter MetrOhm 744) < 3.00 ORP (by Mettler Toledo combination redox electrode) > 1100.0 Conductivity (uS cm-1, Ph.Eur. 2.2.38-Curremt Ed.) < 1300 O NMR (Linewidth @ 50% - MHz) 17 < 50.00 Heavy Metals as Yttrium, Zinc, Iridium, Titanium, Zirconium, Ruthemium by EPA 200.8 1994 (0.1 μg/l detection limit) < 0.1 ppm Heavy Metals as Ag, As, Bi, Cd, Cu, Hg, Mo, Pb, Sb, Sn < 10 ppm R Free Chlorine is mainly (> 95%) comprised by HClO (Hypochlorous acid) Main features Stability Purity HCLO is stable over time at different conditions Stability in ICH Conditions: Industrial batch (lot LCOX/5) : - 18 months at 25°C ±2°C and 60% ±5%HR (still on going) - 6 months at 30°C ±2°C and 65% ±5%HR and 5°C ±3°C - 3 months at 40°C ±2°C and 75% ±5%HR In Use Stability: Industrial batch (lot LCOX/5) : - daily opening and sampling for 5 consecutive days - 6 month-storage + sampling + 3 month-storage at 25°C ±2°C and 60% ±5%HR - 6 month-storage + sampling + 3 month-storage at 30°C ±2°C and 65% ±5%HR Efficacy The purity HCLO is highly effective at killing harmful patogens and spoilage organisms. It is about 100 times more powerful as oxidant and disinfectant than is hypochlorite ion. Bacteria Viruses Bacterial Endospores Fungi Acinetobacter baumannii Escherichia coli (0157) Enterococcus species (VRE) Helicobacter pylori Listeria Legionella pneumophila Mycobacterium avium-intracellulare Mycobacterium terrae Mycobacterium tuberculosis (TB) Mycobacterium xenopi Mycobacterium smegmatis Pseudomonas aeruginosa Staphylococcus aureus (MRSA) Samonella cholerasuis Bacillus cereus Bacillus subtilis Clostridium difficile Clostridium sporogenes Adenovirus type 4 Bacteriophage MS2 Hepatitis A & B (HAV) Herpes virus type 1 HIV-1 Human and Animal Influenza H5N1 Avian Influenza H1N1 Swine Influenza MS2 virus Human Norovirus (Norwalk) Murine Norovirus Orthopoxvirus Poliovirus type 1 Poliovirus type 2 Aspergillus niger Candida albicans Trichophyton mentagrophytes R Safety Being Purity HCLO the replica of the HCLO produced by the human immune system is safe for the man and environment. Indead the human body produces an highly effective antimicrobial solution called hypochlorous acid to fight infections. The HCLO produced by the immune system: - Reacts readily with a variety of microbial sub-cellular compounds. - Interferes with their metabolic processes. - Kills individual bacterium exposed within milliseconds. IMITATING THE HUMAN BODY Human Body + Water HCLO Salt Patented Nano Process Salmonella Norovirus E.coli MARSA etc. Safe for Humans Several tests according to international standards concluded that there are no known health risks associated with intended used. - No Skin Sensitization - No Skin Irritation - No Dermal Toxicity - No Eye Irritation - No Inhalation Toxicity - No Oral Toxicity - Non-Mutagenic Safe for the Environment Purity is completely biologic, leaving other than water in the environment. No Antibiotic Resistance The overuse and misuse of antibiotics have lead to the proliferation of “superbugs” such as MRSA. Purity is effective against all types of bacteria, including MRSA, and do not contribute to antibiotic resistance. R Introducing purity HCLO fog “... The new availability of hypochlorous acid vapor, combined with the solid technology of humidification system, can now become nothing less than the definitive solution to a serious, expanding national and international health dilemma. The disinfecting quality, safety and efficiency can be effectively and economically assured...” Dr. Kenji Uchino Dr. Yongkang Gao Materials Research Institute The Pennsylvania State University University Park, PA 16802 The Purity stabilized HCLO Fog represents a revolution in the disinfecting industry. - the most powerful disinfectant in the world, - 100% compatible with the presence of human being - green and safe for the environment. It represents the best way to disinfect both air and surfaces. The fine fog penetrates into hooks and crannies and fabrics, there is no hiding place for germs and bacteria. Our Patented technology in nebulizing the HCLO guarantees the finest fog without wetting exposed surfaces. * CLAIMS SUPPORTS ARE AVAILABLE ON REQUEST R Our technology The PURITY HCLO FOG patented technology is based on fractal frequency technology. The process creates a consistent HCLO Solution droplet size of 4.2 microns, which is distributed in the air in a consistent and controllable dimensional delivery. Since the droplets are uniformly sized and distributed, you get even, precisely-controlled distribution in the environment 4.2 Micron droplet The secret of Purity HCLO Fog lies in the small droplet size of the HCLO Solution and the engineered spacing between the air and HCLO Solution. Purity Hclo Fog System has succeeded in manipulating the droplet size to be the smallest in the industry. Why is the droplet size important? HCLO Solution evaporates only from the surface of the droplet. If the surface area of the droplet in relation to the volume of Solution is decreased, then the evaporation efficiency is increased. The smaller the droplet size, the longer it can stay air bourne. Therefore, the smaller the droplet size the fastest and efficient distribution is achieved. FOG CLASSIFICATION DROPLET TIME FOR PARTICLE TO FALL 10 FEET (SECOND) SIZE Wet Fog 11-49 40 - 1,020 Dry Fog 6-10 1,019 - 12,000 Purity HCLO Fog 2-4 12,001 - 25,400 COMPARISON Purity Hclo Fog Steam Air & Hclo Ultrasonic High-Pressure Centrifugal R The adhesion concept Purity Hclo Fog technology utilizes a natural de-correlation process. Correlation refers to the cohesion and adhesion properties in the liquid. Cohesion: a liquid is attracted to other liquid. Adhesion: a liquid attracted to other materials. Purity Hclo Fog De-Correlation Technology reverses the cohesion and maximizes adhesion. Furthermore, dust and air borne diseases, bacteria, viruses partcles and spores are attracted to the Purity Hclo Fog droplets by adhesion and are oxidized. Droplets of 5 microns or larger naturally retract air particles, and doesn’t suppress any dust or other air bourne particles. According to researchers to use of Purity HCLO Fog aids in to reduction of dust and air borne bacteria/viruses from the air. Purity HCLO Fog Droplet Droplet above 5 micron Intelligent precise distribution control Purity HCLO Fog systems are equipped with a CPLC controller which utlizes our propriety intelligent algorithms to identfy the most efcient way to generate the required humidity for any given environment. The PY100 HCLO Fog producer includes the following components: - PY100 Humidifier - CPLC Intelligent Controller - PY100 PB Control Center - S-Series Relative Humidity & Temp Sensor R Application field in air and surface treatment Purity is a system that disinfects the environment starting from the main factor of contagious that is the air itself. Moreover due to the characteristic of the HCLO it can be used in every environment without the need to evacuate people. A crowded place represents a very dangerous place. Indeed viruses and bacteria travel from people to people through hands, air, water, and environmental surfaces. As many studies underlines there is a relationship between the viral transmission and the distance from the infecting agent. (Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant; PJ Marks; Epidemiologic. Infect. 2000, 124: 481-487) The quality of the environment plays an important role in the transmission of infections The air flow design in the building becomes more and more important and the filters becomes more and more sophisticated. A sanitized air more than the mechanical disinfection of the surfaces is the key to reduce the infections problems. Today everybody relies on filters technology that do not definitively solve the problems, indeed even the most sophisticated filters just trap the bacteria and become a sink where they reproduce and become stronger. The air ducts themselves represent a problem and without the proper maintenance are the first route to the epidemics. FOOD HANDS H2O ES AIR Air purification test: The Purity HCLO Fog safely reduces fungal and bacteria load in the environment. Virtually every environment can be sterilized without the need to evacuate occupant! R Communities safety The process creates a consistent HCLO droplet size of 4.2 microns, which is distributed in the air in a consistent and controllable dimensional delivery. Since the droplets are uniformely sized and distributed, you get even, precisely- controlled HCLO concentration that efficiently react with whatever it touches. Purity HCLO fog rapidly disinfects air and surfaces to protect people from the spread of infectious pathogens implementing cost effective preventative safety programs. (E.Coli, Human and Animal influenza H1N1, H5N1, Norovirus, MRSA, TB etc.). Moreover it reppresents a breakthrogh solution to viral outbreak and bio-decontamination. In the graphic below we can see the contamination level of environment with and without the Purity treatement. Laboratory studies states that Purity HCLO fog is higly effective also on hard surfaces. Here below the results of its applications on contaminated food preparation surfaces. BACTERIA Salmonella Typhimurium S. aureus E. coli L.monocytogenes 30 s with water 8,53±0,16 8,89±0,01 8,60±0,09 8,67±0,07 30 s with PURITY HCLO N.D. b N.D. b N.D. b N.D. b In the same environment we can see how in selected surfaces the bacteria load decreased after a period of Purity HCLO exposure. The data show the decreasing of 8 log of bacteria population. R These facts open the door to multiple applications and Purity stabilized HCLO really becomes the definitive solution to bacteria and virus problems representing the fastest and most economic way to solve them. Indead the system being 100% safe can be used in the presence of humans. This means there is no need to evacuate treated environment and there is no need to rinse treated surfaces and objects. The treatment is suitable for small and large surfaces and can be integrated in the A/C central system to automatically treat different environments. Moreover this kind of installation solves the maintainance of the system keeping the filters and the ducts system free of bacteria. Industrial Unit Fog Tunnel Other customized solution available. Portable Unit R Specific Case: Food Safety Killing harmfull patogens and spoilage organisms Purity stabilized HCLO fog protects food from cross contamination and keep perishable products safer fresher longer. This technology rappresents a revolution in food industry (food packaging, logistic, catering industry, restaurants, hotels, schools, hospitals etc.) improving profittability, reducing waste and improving safety and customer satisfaction. Effects on meat and vegetables Bacteria exposure leads to decomposition and infection risk co li E. to ge ne s eu s L. m S. a ar ic C In the picture we can see the effect of Purity HCLO exposure on pepper. The pepper A was treated with water and pepper B with HCLO. The result after 14 days storage is clearly evident. 5 120 100 4 80 60 ur e es m on m L. ar ic B 80 hi m to ta l of il a E. oc y to ge ne s eu s au r S. ur e hi m to ta l a Ty p es m on m L. S. of il a E. to ge eu s oc y S. au r ur hi m to ta l Ty p a of il S. es m C C Meats were contaminated before the tests. (*) Results logarithmic reduction. Reduction by 1 means 10 reduction by 2 means 100 and so on. Example: the result on poultry for S. Aureus was 1.79 logarithmic that means 61 times less than the original contamination 100 oc y 0.00 au r 0.00 on 0.40 iu m 0.40 0.00 S. 0.40 co li 0.80 iu m 0.80 co li 0.80 ne s 1.20 iu m 1.60 1.20 e 1.60 1.20 A Bovine 2.00 1.60 ar ic a Poultry 2.00 Ty p Swine 2.00 3 60 40 2 40 20 1 20 0 0 Trattato Non trattato Fruit Hardnes Reduction 0 Trattato Non trattato Respiratory Intensity Pick (The Pick was registered 3 days for no treated products and 6 days for the ones washed with HCLO.) Trattato Non trattato Logarithmic reduction of bacteria load. R Purity HCLO Fog Products PY 100 The PY 100 is an easy to use “plug and play” non wetting HCLO fog producer. It is designed to meet the requirements of a majority of commercial, industrial and agricultural applications. There are several different models to choose from. PY 100 Mobile Bring portability to your commercial humidifier needs. The PY 100M is a complete plug and play mobile HCLO fog producer that is perfect for on-the-go applications. PY 100 Large For larger apllications needs, we present the PY100L . This model was engineered for complex, large-scale applications such as operations over 10.000 sq feet. PY 100 Sky This model was specifically engineered for aircraft treatment. It is designed to treat private, cargo, and commercial aircraft. PY 100 Sea This model was specifically engineered for ships treatment. It is designed for complex large scale application in private, cargo and commercial cruise ships. While the actual specs vary by model, some of the common features and benefits include: Low pressure, only 100 PSI HCLO distribution control up to 99% environment saturation without wetting surfaces Uniform droplet size (as small as 4.2 microns) Low energy consumption Simple installation, low maintenance, fully automated R PY 100 PY 100 L PY 100 M