National Journal of Research in Ayurved Science
Transcription
National Journal of Research in Ayurved Science
ISSN 2320-7329 ISBN 978-93-5173-179-3 MUDITA PUBLICATIONS PVT. LTD. Ayurlog National Journal of Research in Ayurved Science A Peer-Reviewed Open Access Electronic Journal of Ayurved Vol. 2 Issue 2nd April 2014 Advisory Board: Chief Editor: Dr. P. A. Dudhamal, Chief Advisor: Dr. Madhukar Lahankar, Asst. Editor: Advisor: Dr. Ranjana More, Dr. Raju Dudhamal, Dr. Pradnya Dudhamal Dr. Ravi More, Dr. Arun Dudhamal, Dr. T. S. Dudhamal, Dr. S. S. Dongare i www.ayurlog.com; Email: [email protected] INDEX Article No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Title Author Case Presentation of Quadriparesis with Odontoid Fracture To study the efficacy of “vatatwakKwatha” for yonidhawana in Kaphajyonivyapad w.s.r. to Trichomonas Vaginitis. AMA & FREE RADICAL THEORY EFFECT OF SOOKSHMA TRIPHALA IN POST OPERATIVE SURGICAL WOUND CARE WITH SPECIAL REFRENCE TO WOUND FIBROSIS THE ROLE OF GOKSHURBEEJ CHURNA, HONEY AND AVIKSHEER (SHEEP MILK) ON URINARY CALCULUS To assess the amalaki Rasayan effect in geriatric problems Case Report of Ligament & Menisceal Tear Of Knee Joint CLINICAL STUDY OF LAGHUSUTASHEKHAR ON AMLAPITTA Effect of Praval Bhasma on Diabetic Neuropathy ROLE OF PANCHA TIKTA GHRUTA MATRA BASTI IN PROCTITIS. A COMPARATIVE STUDY OF MEDOSARA AND MEDOVRIDDHI WITH RESPECT TO SERUM CHOLESTEROL Ayurved management in LUMBAR CANAL STENOSIS: A case study The Role Of Ayurvedic Medicine (I.E. Vanga Bhasma, Guduchi Satva & Pravalpishti) In The Management Of Dhatukshayajanya Sandhigatvat AYURVEDIC MANAGEMENT OF MYOTONIC DYSTROPHY: A CASE REPORT ROLE OF SHIRODHARA IN NIDRANASH Anu V.Singh, Geeta D Parulkar 1-7 Vaishali Prakash Pol, Jayashree Patil 8-16 Gaikwad Madhavi Dattatray Shailendra D. Katakdound 17-25 26-31 Rajesh Chandrakant Pandit 32-36 Vanita N. Puri 37-42 Gayatri B.Pund, Raman R. Ghungaralekar Prafull S. Yashwantrao, Minal Vaidya Komal S.Raut, B.D. Gharjare 43-49 Moghal Hasan, Sanjeev Yadav Jaykumar Sadashiv Ade 62-66 Naik Minal S., Meenakshi Rewadkar-Kole Sanjay A. Pawade, Umesh N. Patil, R. J. Mundane 77-82 Ketaki Jalinder Jadhav, Prerana P. Jawale Sujata Jadhav 91-99 ii Page No. 50-54 55-61 67-76 83-90 100-108 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Editorial: Upcoming era is factual era. No one can belive in hypothetical concepts. Changed world is signing Ayurvedic experts to accept challenges of this era. The equation of health problem always changes with the lifestyle. Now days, infectious diseases are mostly controlled by antibiotics but viral challenges are still existing like AIDs, Swine flue etc. AYUSH system of Medicine is having lot of Scope in the maintaining and restoring health. We have to search the distinguished path and took lot of efforts to resolve unsolved health problems by allopathic medicine. By the active participation of all Authors, Editorial Board Members and All well wisher, Thanks for giving faithfully support to Ayurlog. Chief Editor, Ayurlog: National Journal of Research in Ayurved Science iii ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_1 ______________________________________________________________________________________________________________________________________________________ CASE PRESENTATION OF QUADRIPARESIS WITH ODONTOID FRACTURE-A SUCCESSFUL TALE OF AYURVEDIC TREATMENT ________________________________________________________________ Anu V. Singh*1, Geeta D. Parulkar2 ________________________________________________________________ 1. M.D. ( Scholar) Final year, Kayachikitsa Dept. 2. Associate Professor, Kayachikitsa Dept. Email: [email protected] R. A. Podar Medical College R. A. Podar Medical College *Corresponding Author: [email protected]; ________________________________________________________________ Hetu, ABSTRACT:- Poorvaroopa, Roopa, Upashayanupshaya and Samprapti forms Quadriparesisis a prevalent and the stepping stones of Ayurvedic diagnosis. disabling neurological disorder which arises This case was a diagnosed patient of from multiple etiologies like severe Quadriparaesis with type Hypertension, Lacunar infarct, Motor fracture. He had taken allopathic treatment vehicle accidents, Tumors’, Spinal Cord earlier for 1 month under supervision of Trauma. It produces a very miserable , various experts and was even admitted in dependent and prolongs crippled life with I.C.U for first seven days. Keeping in view constant mental trauma .The mainstays of with Nidaana Panchaka Quadriparaesis can treatment for Quadriparesis differs be correlated with Sarvangavata. The according to their cause but none of them treatment was given according to Ayurvedic proves to be a gold standard in the treatment principles The aim of this article is to prove of Quadriparesis. the efficacy of Ayurveda in a disease in 1 II Odontoid ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ which even Allopathy has its own Type III-Fractures of Odontoid which is limitations due to limited range of treatment extend into the body of C2. and due to cost effectivity. This case clearly Treatment includes Halo immobilization has portrays the successful tale of Ayurvedic been considered the stand of care, although Treatment in case of Quadriparesis due to its applicability to both trauma patients with type II Odontoid fracture. associated head and /or chest injuries and KEYWORDS: Quadriparaesis, Odontoid the elderly population is limited. An Fracture, Nidaana Panchaka, Sarvangavata alternative is anterior odontoid screw fixation following reduction with traction[1] INTRODUCTION: CASE REPORTS Quadriparesis is defined as a Case History condition in which patient experiences weakness in all four limbs. In this case the cause of Quadriparesis was Patient Name- XYZ Age -26 years,Sex - Male Type II Odontoid Fracture which occur due to Motor vehicle accident .Odontoid fracture Residence -Mumbai,Occupation - Taxi driver are notoriously prone to nonunion .They may cause neurological impairment and even death. Odontoid fractures are common D.O.A -27/09/13 D.OD- 14/01/14 cervical spine fracture representing up to C/O: 20% of all cervical spine fractures .The classification of these injuries was proposed Weakness over both upper and lower limb Restricted and painful movements of neck Unable to sit , stand ,walk by Anderson and DˈAlonzo and is based upon the location of fracture line. Type I-least common, occurs at the tip of odontoid Pain over left lateral side of chest Type II-most common, the fracture line is at Anorexia and weight loss the junction of odontoid base and body 2 1 month 1 month 1 month 1 month 1 month ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ History of present illness – RTVC, RTDS Pupils: Semi-dilated RTL Plantar- B/L Patient was apparently all right Flexor before 1 month. Then he got traumatized in a road traffic accident on 29/08/13. Patient DTR was traumatized due to bike accident which results in injury to knee, neck and left hand followed by head injury.Then patient was admitted to Sion Hospital. H/O unconsciousness present, H/O vomiting, H/O urinary and stool incontinence at time Jerk Knee Ankle Bicep Right Left 4+ 4+ 4+ 4+ Tricep Absent Absent Absent Absent MPG of admission.No H/O blunt chest trauma / Muscle Tone – abdominal trauma .Patient was given Rigid neck collar and water bed at the time of admission.Patient was hospitalized for 1 Upper limb Lower limb month in Sion hospital.Then patient came to Right I/V III/V Left I/V III/V our hospital innonambulatory position on a stretcher with rigid neck collar around his Spastic, S/O neck stiffness present due to neck with abovesaid complaints. Fracture Past history- P/A – mild tenderness present over epigastrium ,U-passed ,S-passed No H/O any medical or surgical illness. S/O Pallor and malnutrition present. O/E: Investigations done: G.C. fair, afebrile, P-68/min , B.P-90/50 CT (Brain) on 29/08/13 mm of Hg RS- Air entry decreased in Lower lobe of Linear undisplaced fracture noted at the base of odontoid processs left lung bilaterally.Rest normal. CVS-S1S2N ,CNS –Conscious , oriented 3 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ MRI (Cervical Spine with WSS) on Treatment Given: 31/08/13 The basic principle of treatment according Type II odontoid fracture with to text includesSnehanafollowed which retropulsion of the dens causing mild svedanais executed and to pacify remaining spinal canal narrowing . Doshassamshodhanais given to patient.[3] Acute haemorrhagic cord contusion at C1C2 level. SarvangaSnehanaand NaadiSvedana. Screening dorsal and lumbar Spine reveals Fracture in D3 and D4 MamsarasaSevana with Goghrut T.D.S vertebral bodies with their partial collapse . Complete sacralisation of KsheerbalaTaila (Shatapaki )abhyantarpaanarth 4 drops in milk L5 vertebra seen. B.D. NidaanaPanchaka: Ashwagandhrishta and Balarishta each 10 ml with 100 ml of water. Hetu :Aghaataja BruhataVataChintamani 125 mgvyaankale till 04/11/13with Poorvaroopa:Avyakta honey Roopa:Ubhayahasta padaakarmanyata Lakshmivilasa Rasa 500 mg vyaankale with honey. Samprapti:Vata gets vitiated due to various etiological factors whole body Vata gets hold of SanjeevaniVati 500 mg vyaankalewith honey. Vata dries up sira and snaayu, loosens sandhibandha and produces Laghumalinivasanta Rasa 250 mg vyaankale with honey. pain[ 2 ]Nidaana: Sarvangaroga Pindasveda for 14 days (since 30/12/13 to 11/01/14). Diagnosis According To Modern Medicine: Quadriparesis RESULTS: 4 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Before Treatment After Treatment Ability to sit,stand,walk Unable to sit ,stand,walk Can sit,stand,walk on his own Respiratory System Air entry decreased in lower Air entry bilaterally equal lobe of Left Lung and pain and pain disappears over over left lateral region of left lateral region of chest. chest. Reflexes Reflexes Before After Treatment Treatment Right Left Right Left Knee Jerk 4+ 4+ 4+ 4+ Ankle 4+ 4+ 4+ 4+ Bicep jerk Absent Absent 2+ 2+ Tricep Absent 2+ 2+ Jerk Absent jerk MPG: Upper Before After Treatment Treatment Right Left Right Left I/V I/V IV/V IV/V III/V III/V IV/V IV/V Limb Lower Limb DISCUSSION: 5 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Kalpas Contents Quadriparaesis is a neurological Pradhana Karma condition Maamsarasasevan Ajamaamsarasa which can be correlated Balya, withSarvangavatawhich predominantly has Maamsavardhaka Vatadominance .Vata vitiations may be KsheerbalaTaila Godugdha,Bala, Tiltaila (Shatapaaki ) Naadisvedana.BruhataVataChintamaniis Ashwagandha, Manjishtha, having soothing Vataghna,Jatharagnideepaaka effect on the nerves. Ashwagandhrishta Balya,Vataghna and relieved bySarvangasnehana Haritaki, Haridra, Daruharidra, Sarvangavatais relieved mainly Rasna, Yashtimadhu, Vidarikanda byBruhatVataChintamanias it acts mainly Balarishta Balamoola , Ashwagandha,as an excellent Balya,Jathragnideepaka cell rejuvenator and helps in Ksheerkakoli, Erandamoolatwak, preserving energy and strength of the Rasna ,Gandhaprasarini , muscles,nerves and the human mind. Lavanga,Usheera, Gokshura Bruhata Vaata Suvarnabhasma, Rajatabhasma, SarvangaSnehana withTil Oil Vatapittaghna,Vrushya Chintamani Rasa Abhrakabhasma , Lohabhasma, andNaadiSvedanawithDashmoolaK Pravalabhasma, Mauktikabhasma, wathais helpful in Vatashamana, Rasasindura Jathragnivardhana thus, helps in Lakshmivilasa Suvarnabhasma ,Rajatabhasma, [4] strengthening SaptaDhatus. Tridoshaghna, Vrushya, Balya Rasa Abhrakabhasma , Tamrabhasma, Ajamamsarasa is laghu in nature Vangabhasma, Kantalauhabhasma,and easy to digest as well as Balya Mundalauha, Naagabhasma, and hence, results in Vatashamana Vatsanabha, Motipishti, as well as rekindling the digestive Rasasindura fire. Agnideepaka used for KsheerbalaTaila Haritaki, Amalki, Bibhitaka,Vacha,‘AabhyantarPaanarth’ isBalya in SanjeevaniVati Vidanga, Shunthi, Pippali, Laghumalini Guduchi, Bhallataka, Vatsanabha nature, which ultimately results in Rasaka, Maricha Balya,Deepaka,Paachaka Vatashamana and also results in Vasanta Rasa Mamsadhatuvardhana.[5] Probable Mode of Action: Bruhatvatachintamani isBalyaas well as Vrushya in nature . It is the ace in the treatment as it is 6 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Vatapittashamakabasically and acts mainly to removeSnayuand Naadidaurbalyathereby enhancing motor and sensory activities .[ 6 ] 3. Pindasvedaby Shastikshali acts forBruhanakaryaso results in Vaatashamanaand Mamsadhatuvardhana. 4. CONCLUSION : It can be concluded from above mentioned results that Ayurvedic therapy is effective in relieving Quadriparesis. Thus, symptoms of 5. Sarvangavata described by AshtangaHrudyam is similar to that of Quadriparesis and can be well treated. 6. References: 1. Torreti JA, Sengupta DK. Cervical Spine trauma. Indian J.Orthop. (serial online) Available from http://www.ijoonline.com/text.asp.2 007 [Accessed on 2014 February13] 2. Srimadvagbhata, “Ashtanga Hrudayam” with Nirmala Hindi Commentary by Dr. Brahmanand Tripathi Niadana Sthana Chapter 15 ,Verse No.38-40 Chaukhamba Sanskrit Pratishthan , 2009. Page No.542 Srimadvagbhata, “AshtangaHrudayam” with Nirmala Hindi Commentary by Dr.Brahmanand Tripathi ChikitsaSthana Chapter 21, Verse No.44 Chaukhamba Sanskrit Pratishthan, 2009. Page No.809 Agnivesha, “CharakaSamhita” with Caraka Chandrika Hindi Commentary by Dr.Brahmanand Tripathiand Dr.Gangasahay Pandey,Chikitsa Sthana Chapter 28,Verse No.81-82 Chaukhamba Surbharti Prakashan ,2008, Page No.952. Srimadvagbhata, “Ashtanga Hrudayam” with Nirmala Hindi Commentary by Dr. Brahmanand Tripathi Chikitsa Sthana Chapter 22, Verse No.44-45, Chaukhamba Sanskrit Pratishthan , 2009. Page No.821 Kaviraj Govind Das Sen , “Bhaishajyaratnavali” with Siddhiprada Hindi Commentary by Siddhinandan Mishra Vatavyadhavyadhirogadhikar Chapter 26, Verse No. 143-144 Chaukhamba Surbharti Prakashan, 2011. Page No. 530 Cite this article: Case Presentation of Quadriparesis with Odontoid Fracture Anu V.Singh, Geeta D Parulkar Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2): 1-7 7 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Article_2 Clinical efficacy of “vatatwakkwatha in management of Kaphajyonivyapad (Trichomonas Vaginitis) ___________________________________________________________________________ *Vaishali Prakash Pol1 Jayashree Patil2 ___________________________________________________________________________ 1. PG Scholar Stree-rog vum Prasutitantra, YAC College, Kodoli. 2. Lecturer, StreerogvumPrasutitantra, YAC College, Kodoli. * Corresponding Author: Email Id: [email protected] , Mob. 7875597635 ___________________________________________________________________________ proper screening of the efficacy of the drug Abstract:- Total 30 female patients of Trichomonas The word “StreeRoga” describes about Vaginitis were selected for 7 days in this pathological conditions of stree, a female study.Finally effectiveness of drug is who is in menstrual phase. It is clearly assessed. denotes the genital and perigenital problems specially limited to woman starting from Keywords: Kaphajyonivyapad, menarchae to menopause. Trichomonas Vaginitis, &vatatwakKwatha. Trichomonas Vaginitis is one of the INTRODUCTION: common gynaecological problems faced in The illness based on the female genital tract daily practice. A clinical trial was conducted is known by the name “Yonivyapada” on patients of Trichomonas Vaginitis. The word Yoni refers to the different parts Patients were treated with of female genital tract or whole genital vatatwakKwatha(FicusbenghalensisLinn)for system including Hypothalamo Pituitary yonidhawana(vaginal irrigation ) For a ovarian axis. 8 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Certain diseases may not be life threatening the best and the most specificprocedure as but an mentioned in this contextstudy has been day completed on the role of “vatatwakKwatha” is for yonidhawana in Kaphajyonivyapadw.s.r. troublesome and individual in irritating to day to routineactivity.”KaphajaYonivyapada” one of among them increasing day by day to Trichomonas Vaginitis. and demanding greater concern over it. If It SAMPRAPTI: (ETIOPATHOGENESIS) is left untreated may leads up to infertility, premature labour, abortions and predisposes In the manifestation of yoni rogas, it is to malignancy(Jeffcoate’s)5. That’s why it observed that there is dominance of vata is one of the most common disease in population and is majorhealthproblem merging in the as along with other doshas and dushyas. a developing Charaka world. and Vagbhata described the samprapti of yonivyapadas in following pattern, dueto their ownreasons, first the Cardinal symptoms of KaphajaYonivyapada are Yoni Yonistrava Kandu(vaginal (vaginal discharge) Yonivedana(pain at symptoms burning are doshas become deranged and get united in itching), vagina). yoni and garbhashaya producing signs, and symptoms and complications. Other micturation, dyspareunia. For Trichomonas Vaginitis. Kapha, vitiated duetoexcessive use of abhisyandi (articles The treatment It is observed that the effect Producing of treatmentwhich use to give for substances reaches reproductive system& Trichomonas Vaginitis is temporary one and causes unctuousness, coldness, itching & chances of recurrence of the disease are dull pain in vagina. The woman looks high so, presentstudy is plannedtoevaluate anemic& discharges yellowish unctuous the effect of Ayurvedicdrugs on the disease. menstrual blood is the opinion of caraka. oozing or serous effusion) As perayurvedicviewpoint, this disease is caused by vitiation of Kaphadosha. So, the Dosha : - Kledaka Kapha, Pachaka Pitta, Samana & ApanaVayu selection of the drug was done according to the nature of the disease and Doshika Dushya : - Rasa, Mamsa, Meda, Artava, predominance. Yonidhawana is considered 9 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Strotodushti: Medovaha - days. Transfer of the organisms from one RasavahaStrotas, Strotas, individualto Artavavaha another by indirectcontact certainly happens. Contaminateddomestic Strotas towels, bed linen and personal clothing, LAKSHAN(Clinical Features): Yonigatstrava Yoni kandu Yoni vedana improperly sterilizedsurgical instruments such as specula, bath tubs and possibly swimming pools are likely media for transfer the optimum pH for the trichomonads is 5.5-6.5 and this or a slightly TRICHOMONAS VAGINITIS higher level is usually found in the vagina (TRACHOMONIASIS) – MODERN when the disease is present. VIEW Pathology This is the most common form of vaginitis The infection is essentially of the vaginal and is found in approximately 50% of epithelium and the parasites shelter between women complaining of vaginal discharge. the rugae. It is possible that they may It occurs at any age from birth onwards but penetrate between the surface cells but most often in young adult. The trachomonas deeper, and they induce the usual tissue group of organisms is found in the mouth, inflammatory reaction. bladder and large bowel. morphological Clinical Features characteristics slightly different from the others. It is an ovoid motile flagellated A parasite 15-20 μm in width, although discharge, the itching being felt around and smaller forms are described. It has four within anterior flagella and an axostyle which tenderness traverses its body to end in a spike. dyspareunia. sudden onset of theintroitus. and purulent Dysuria vaginal Vaginal congestionresult in The vagina may be diffusely fiery red in The infection is often contracted during colour intercourse with a male harbouring the but appearance. organisms in the prepuce, urethra or prostate, the incubationperiod being 3-28 10 often present strawberry ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Research study conducted on Vata/ 2) To study the effect about the drug Trichomonas Vaginitis from internet. “vatatwak Kwatha” in kaphajyonivyapad w. s. r. to Trichomonas Vaginitis. Wound-healing activity of ethanolic and MATERIALS& METHODS: aqueous extracts ofFicusbenghalensis Aqueous Extract MATERIALS: of Ficusbengalensis Linn. Bark for Inflammatory Bowel Disease Inclusive criteria: Development of quality control parameters for the standardization of Patient irrespective of caste, income stem bark of Ficusbenghalensis Linn. group and any occupation will be Ficusbengalensislinn.-an overview selected. Prospective study of Patient suffering from kaphajayonivyapad. trichomonasvaginalis infection and prostate cancer incidence and mortality: Age group: - 18 – 35 yrs. physicians' health study. Exclusion criteria Sexually transmitted parasite trichomonasvaginalis twice as prevalent Patient suffering from Major illness e.g. in women over 40, study finds malignancy, TB, HIV etc. AIMS & OBJECTIVES: Cervical for yonidhawana Bacterial infections, Gonorrhea, Syphilis, Pregnancy Aims: To study the efficacy of “vatatwak Kwatha” lesions, in Vatatwak Kwatha Kaphajyonivyapad w. s. r. to Trichomonas Charaka Vaginitis. has mentioned vatatwak Kwatha[13]. Objectives: Vatatwak Kwatha is prepared by collected 1) Tostudy the KaphajYonivyapad w. s. r. to in to kwathapatra & added to 16 times of Trichomonas Vaginitis water & it is kept overnight, next day morning, in both modern & Ayurvedic classics. 11 contents are heated over ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ mriduagni (low Temperature) till total assessment of result as mentioned in the contents get reduced to ¼ part, then contents table-1. are filtered with clean cloth and the obtained 1) Yoni kandu kwatha was used for yonidhavan. 2) Yoni strava METHODS: 3) Yoni vedana 30 patients of Trichomonas Vaginitis from indoor & outdoor department were selected Table-1Gradation of clinical features: and diagnosed on the basis of sign and symptoms. Freshly prepared 500ml Grade vatatwakKwatha was used for yonidhavan 0 daily in the morning up to 7 days. Yonidhavan was done in three stages: 1 1) Purva karma, 2) Pradhan karma 3) Pashchyat karma All The above said Karma are done with aseptic precautions. YONI KANDU YONI STRAVA No H/O Yoni vedana Occasion al No H/O Yoni kandu No H/O Yoni strava No disturban ce in daily routine Need to take rest, unable to Occasiona l 2 Follow up of all patients was done do routine work Need to take analgesic, on 15th day for recurrence of symptoms. YONI VEDANA Total absence of intercourse was advised for the period of 15 days. 3 Criteria of assessment: The patients were diagnosed on the unable to do routinew ork Need to scratch, unable to do routine work Excessive scratching , disturbed sleep No H/o staining undergarme nt Slight staining of under garments Need to put some sanitary pad Trial Group basis of signs & symptoms of the disease and confirmed on per 30 speculum Patients dhavanwith examination. The gradation adopted for 12 treated only with Yoni vatatwakkwath for ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ consecquentive 7 days. For yoni dhavan 3) Bed pan was kept. amount of the vatatwakkwatha 500ml was used and As per 4) Freshly prepared koshna Kwatha was textual used. reference,yonidhavan was done in three stages :i.e. purva karma, pradhan karma and pashchyat karma as with 5) Equipments were connected serially, aseptic Kwatha poured in enema can. precautions. B. Pradhanakarma : Procedure of Yonidhawana: 1) Enema can was held at 2 – 2.5 feet height SthanikChikitsahas been enumerated as an by an attendant. important part of YonivyapadaChikiitsa. 2) No kinks were kept in a tube. Instruments used for Yonidhawana: 3) Nozzle key is opened. 1) Douche Can : - It contains one cylindrical 4) Bahya yoni prakshalan was done by can, one tubular separating labia majora with left hand. pipe, nozzle key and nozzle. 5) Labia majorawas separated to find out 2) Long Artery Forcep. vaginal orifice. Then tip of the nozzle inserted into the vagina about 4 – 5 inches 3) Swabs and yonidhawana was done. 4) Labor Table C. Paschatkarma :1. Patient was advised to lie down on 5) Drug :-vatatwakkwath500 ml. table for 10 min. A. Purvakarma : - 2. After this vagina was cleaned with the help of swab and long artery 1) Patient was made to void urine. forceps till the swab became dry. 3. Patient was advised for total absence 2) Patient was made to lie on a table in of intercourse for 15days. lithotomy position. 13 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ In present study Strava was present in all 30 DISCUSSION: patients The discussion while studying the efficacy treatment. There was complete cure in 26 patients by 7th day of Yoni dhavanwith vatatwakkwath For the where as 4 patients remained in the present study internal medication was not given before improved category. since P value < 0.05. orally and also vatatwakkwath Yonidhawana was given. Sthanik chikitsa On Yoni Vedana has been enumerated as an important part of In present study Yoni Vedana was present Yonivyapadachikitsa. in 30 patients before treatment. There was Probable mode of action of Yoni dhawana : complete cure in all 30 patients by 7th day. since P value < 0.05. 1. As the name Dhawana suggests cleaning, it washes outthe secretions & Discussion discharges of vagina. therapies on overalleffect of the 2. The action is mainly by the drugs used In present study out of 30 patients complete in preparation ofthe kwatha. cure was found in 81.25%, where as 18.75% 3. It deals with the altered pH of vagina patients remain uncured. thus not favouringthe micro-organisms invasion. Discussion on Recurrence of the therapies 4. The action of drugs used is kandughna, stravaghna,shulaghna properties. In present study there was no recurrence of the disease, It indicates that the effect of On Kandu Ayurvedic therapy on the Recurrence of Kaphaja Yonivyapada was more significant. In present study Kandu was present in all 30 patients before treatment. There was Observations: complete cure in 28 patients by 7th day where as 02 patients remained in the improved category. since P value < 0.05. Kaphaja Yonivyapadain modern parlance has similarity with the disease Trichomonas vaginitis. On Strava In the presentstudymajority of the patients were found in the age group of 14 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 21 - 35 years which reflects the incidence of Kaphaja Yonivyapada kaphavardhakaahara with the same type comparatively more in this particular of vihara age range. Even then, studies of a large It was follow that many patients have vata is kashay-rasatmak, katu-vipaka, group of patients were required for the veerya-sheeta, gunas-ruksha and guru. concrete conclusion. so Maximum patients had the history of vedanasthapak kaphakarahara garbhashayashothahara. and Mandagniwhich it acts kapha-pittaghna, and clearly shows the role of Ama formation CONCLUSION in the Majority of the patients of the study were consuming Madhura Rasa Study concluded dominant food, followed by Lavana, dhavan Katu and AmlaRasasreflects that these is that vatakwath effectivein yoni management of kaphajayonivyapad and need to compair Rasas are the supplementary agents for with the standard control group.. the causation of KaphajaYonivyapada. Distribution of the patients according to References: the manifested symptoms showed that 1. Human Anatomy B.D. Chaurasia CBS yoni kandu, yoni strava, yoni vedana Publishers, New Delhi, 4th Edi.,2004, was the cardinal signs and symptoms of Reprint 2006. the disease KaphajaYonivyapada. 2. Essentials of Medical Physiology K. The incidence of kaphajayonivyapad was Sembulingam found higher in low socio- 2000; economic status patients. 3. Text Book of GYNAECOLOGY D.C. The Nutritional status and hygienic Dutta; New Central Book Agency (P) conditions were good in the higher class. Diwaswap, dietic habits, strain, Sembulingam; Jaypee Brothers, New Delhi; 2nd Edi; economic status than the higher socio Prema Ltd.; Calcutta; 6th Edi; 2004. night 4. Dewhurst’s Text Book of Obstetrics & duties were found to be the main causes Gynaecology of kaphajayonivyapad. D. Keith Edmonds Blackwell Publishing, 7thReprint 2011 15 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 5. Jeffcoate’s Principles of Gynaecology 9. Dravyaguna Vijnana; Vol. 2; Prof. Pratap Kumar & Narendra Malhotra; Priyavat Sharma; Chaukhamba Bharati Jaypee Brothers Medical Publishers; 7th Academy; Varanasi; Reprint; 2000 Edition; 2008. 10. Ayurvediya 6. Kasyapa Samhita/Vriddhajivakiya tantra Prasuti Tantra Striroga Part I & II Prof. Premvati Vidyotini Hindi Commentary by Sri Tewari; Satyapala Bhisagacharya; Chaukhamba Varanasi 2nd Edition; 2000. Sanskrit Sansthan; Varanasi; 8th Edition; Chaukhambha Orientalia, 11. Ayurvediya Panchkarma Vijnana; Vd. 2002. Haridas Sridhar Kasture; Baidyanath 7. Sharangdhar Samhita Adhamalla’s Ayurved Bhavan; 7th, 2006. Dipika & Kasiram’s Gudhartha Dipika 12. Susruta Samhita, Prof. K.R. Srikantha by Pandit Parasurama Sastri Vidyasagar Murthy Chaukhamba Orientalia, Varanasi 5th Varanasi Reprint, 2010. Edition; 2002. Banarasidas; Chaukhambha Orientalia, 13. Charaka Samhita, P. V. Sharma, Chaukhambha Orientalia, Varanasi 8th 8. Bhaisajya Ratnavali; Govindas Rachita Motilal Evum Chaukhamba Edi, 2003. th Sanskrit Bhawan, Varanasi 8 Edition; 1976. Cite this article: To study the efficacy of “vatatwakKwatha” for yonidhawana in Kaphajyonivyapad w.s.r. to Trichomonas Vaginitis. Vaishali Prakash Pol, Jayashree Patil Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2): 8-16 16 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_3 ______________________________________________________________________________________________________________________________________________________ CORRELATION BETWEEN AMA & FREE RADICAL THEORY ________________________________________________________________ Madhavi Dattatray Gaikwad ________________________________________________________________ Assistant Professor, Dept. of Rognidan and Vikrutivigyan, C.S.M.S.S. Ayurved College, Aurangabad, Maharashtra, Mobile: 9970431387, Email: [email protected] ________________________________________________________________ has been made here to understand the ABSTRACT correlation between these two theories. Ayurveda, the ancient medical system and the Science of life can be Keywords – Ama, Free Radical Theory, considered as the art of healing and Agni, Agnimandya prolonging life. Philosophical and Scientific AIM & OBJECTIVES – base of ayurveda is the rich store house of hidden treasure of principles and practices. 1. To study the role of Ama in Ama is an important factor in pathology of pathology. any disease. In the present article the theory 2. To study the role of Free Radical in of ama has taken into consideration to pathology of disease. justify the philosophical depth of ayurveda with its contemporary 3. To scientific understand the correlation between Ama & Free Radical. understanding. The cause for production of ama, way of its formation, characteristics INTRODUCTION - and nature of affecting dosa-dhatu-malas The free radicals can be compared with that almost matches with the contemporary of the Ama. In the present clinical concept of Free radical Theory. Thus effort understanding the amavata (Rheumatoid 17 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Arthritis) is compared with the disease When these toxins get retained in the rheumatoid arthritis and the role of free intestine for a longer time, they become radical in causing the rheumatoid arthritis fermented and cause health problems. has been established. Much importance is Mala Sanchaya (Waste accumulation) – given to ama in the manifestation of disease When the body liberates heat and energy, in ayurveda which simulates the Free the tissues get disintegrated and certain Radicals. A correlation between Ama and minute waste products are formed (known Free radicals seems to be strongly possible. as kleda) during this process. Up to a certain AMA - Due to hypofunction of usma limit, the existence of this waste is essential (agni), the food which is not completely or for the body and the excess waste is properly digested, yields immature rasa in excreted. When this excretion process amasaya (Stomach) and due to its retention, becomes inefficient, these waste products undergoes fermentation or putrification.[1] get accumulated in the body, resulting in the formation of ama. Ama can be described as - raw, uncooked, or Dhatu-agnimandya (Low tissue fire) – incompletely oxidized or metabolised or Tissue fire plays an elemental role in the unripe, immature, undigested similar to a poisonous substance. [2] process of dhatu (tissue) formation from nutrient plasma[4]. Thus, when the tissue fire Causes of Ama Production [3] of a particular tissue is diminished, the formation of that tissue remains incomplete Even though a poor digestive fire is and ama is produced. Tissues containing known to be the main cause behind ama, ama are known as Sama Dhatu. there could actually be several other reasons as well. Some of these reasons are discussed Krimi Visha (Bacterial toxins) – During below: infections caused by bacteria or viruses, the Agnimandya (Low digestive fire) – The body liberates toxic substances that can body’s digestive fire performs the task of cause diseases. digesting food in its entirety. However, Ama - root cause of disease when this fire is low, the food we eat is not properly digested and toxins are formed. 18 [3] ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Majority of the endogenous diseases an extra electron from adjacent molecules. actually begin with the formation of ama, Thus free radicals are highly reactive. which has tremendous capacity to vitiate the (Salvemini and Bottling, 1990)[5] dosas, thus disturbing the homeostasis (dhatu-samya). The ama thus Causes of Free Radicals [6] – formed manifests itself either locally (in the G.I.T.) Radiation, or systemically by obstructing the macro ionizing as well as electromagnetic fields and micro channels. The disease thus produced, clinically manifests itself in form Sunlight & ultraviolet light, especially UV- of various signs and symptoms. These signs ray, Pollution, Toxic metals, Pesticides, and symptoms are the principle tools used Chemicals and Pharmaceuticals. by a physician to diagnose the disease and Oxidation – Smoking, alcohol, diet. treat it promptly. ama and various diseases produced by it may be identified / diagnosed Free radicals are produced in a number of by looking for a number of objective and ways in biological system. subjective symptoms, which have been Free Radical Theory – described in various ayurvedic classics. But with the recent trends of thinking, the latest Attributed to Denham Harman (1950) approach to the study of the physiological as well as pathological states of the human Lifespan beings has been directed more to the is in inverse proportion to metabolic rate. parameters which are better understood either by direct cognition or inference based The metabolic rate is proportional to oxygen on laboratory investigations done in vitro. consumption. WHAT ARE FREE RADICALS? Oxygen free radicals lead to tissue damage and ultimately death.[7] A free radical is an atom or molecule that contains one or more unpaired electrons “85% of chronic and degenerative diseases and discontented with such a conformation, are results of oxidative damage.”[8] it will try to seek stability either by donating its electron to other molecule or acquiring 19 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Free radicals are very unstable and react various disease processes.[9] In accordance quickly with other compounds, trying to with the present scientific knowledge, the capture the needed electron to gain stability. excessive production of free radicals in the Generally, free radicals attack the nearest organism, and the imbalance between the stable attached concentrations of these and the antioxidant molecule loses its electron, it becomes a free defenses, may be related to processes such radical itself, and thus begins a chain as aging and several diseases, among which reaction. Once the process is started, it can main are cancer, ischemic processes, senile cascade, finally resulting in the disruption of dementia, a living cell. Due to this acceptance and pancreatic diseases, lupus-erythematosus, donation of free electron, it will make of cirrhosis, intestinal inflammatory diseases, another free radical. The newly produced multiple sclerosis, arthritis, arteriosclerosis, free radical is unstable in most cases and cardiovascular diseases, diseases of the thus it can also react with another molecule central nervous system and the brain. molecule. When the diabetes, pulmonary and to produce another free radical.[5] FREE RADICAL DAMAGE : Free radical – main cause of disease 1. Free radical damage may involve The theory of free radicals which has been any cellular content. These include proven in recent years considers these free mitochondria, radicals (unstable reactive radicals) as the peroxisomes, nuclear endoplasmic main and reticulum and plasma membranes as degenerative changes produced in the well as sites within the cytosol. All cause human body. of [9] many diseases These free radicals may lysosymes, are vital for the normal metabolic damage any cellular content and also functions of the cell. destroy the genetic machinery of the cell. 2. Free radical damage culminates in They produce destruction of the cellular cross-linkages, membrane which results in loss in the inactivation. The genetic machinary organization of the cell may be damaged which is of cellular enzymes, a disturbance in the distribution of nutrients a and dysfunction of cellular metabolism. The radiation. Damage to the DNA sequence of events eventually leads to 20 major disorder denaturation, in ionizing ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ molecule may result in mutagenesis 5. Biological molecules can be raised and carcinogenesis.[10] to higher energy states by exposure 3. Oxygen plays a key role in the to ionizing radiations and thereby generation of free radicals and lipid become reactive. Oxygen makes cell peroxidation. Molecular oxygen is more sensitive to radiation. Oxygen uniquely suited for free radical reacts production because its two unpaired produced by radiation and may electrons cause the molecule to further participate in redox reactions at the reactions within the molecules of the kinetic energy levels available in cells. biological systems. Damage to intra cellular the enhance free the radicals destructive 6. Biochemical reactions are generally lipoprotein characterized by specific, orderly assemblies by oxidant free radicals reactions. However free radicals can have profound adverse effect in react with little regard to selectivity. the cell.[10] They can initiate a chain reaction 4. The membrane, with structure, chemistry and which even at very low functions of these cell membranes concentrations can cause serious are toxic effects in biological systems. extremely complex. When destructive free radical molecules come in contact with CORRELATION these CONCEPT membranes they can produce lipid peroxidation and many malformed substances in the body. disturbance in the distribution of This ama is responsible for the production nutrients and a dysfunction of of various diseases. In the same way free cellular metabolism. This sequence a part of FREE generalized term which can be applied to organization of cellular enzymes, a is AND Ama is not a single entity but is a membrane may result in a loss in the events AMA RADICAL THEORY membrane destruction . The destruction of their of OF BETWEEN radicals are also found to be the root cause the of many diseases. Free radicals can be degenerative disease process and the considered under the umbrella of ama. production of arthrosclerosis.[10] 21 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 1. Free radical is an atom or molecule the healthy molecules of the body that contains one or more unpaired electron, neutralization which by and thus setting a chain reaction. requires free From radical can observe that properties of ama described in classics. incomplete metabolic state which is also the state of ama described as [3] one properties of free radicals are similar to the scavengers. Thus it exists in an avipakvam above PROCESS OF PRODUCTION OF FREE (incompletely RADICALS AND AMA IN BODY - digested/metabolized). 1. 2. Next it is seen that when produced, Free radicals are said to be produced free radicals are in assimilable to in the body in abundance when body components and exist in free equilibrium between its generation state. Similar is the case with ama and body's when it is produced it remains in disturbed. The primary defense of inassimilable state and hence termed the body includes the activity of asamyuktam.[3] certain enzymes like superoxide primary defense is 3. Free radicals cause damage to cell dismutase, catalase and glutathione membrane and thus the cell is peroxidase.[11] The impairment of destroyed. This destruction may lead these to putrification and foul smell production of free radicals. Similarly generation which is similar to one of ama the property of ama described as whenever there is malfunction of durgandham.[3] agni in the body. Many modern enzymes is also can being lead to produced ayurvedic scientists consider the 4. Though ama remains in the body as its action of various enzymes as the properties like bahupicchilam etc. it action of agni. Therefore it may be sticks to normal healthy body tissues concluded that impairment of agni at very quickly. Similar is the case with cellular level causes the generation free radicals. To seek stability in of free radicals.[12] asamyuktam, but due to 2. their structure they quickly attack Some exogenous causes are also responsible 22 for free radical ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 3. production like pollutants, dangerous Depending upon the site and method chemicals, certain food products. All of production many different forms these may be termed under the of free radicals are produced. Ama heading of mithyaharavihara. (faulty also diet and practices). specific types, as each cell of the Certain enzymes produce radicals as body has its own agni and depending intermediary substances, which are upon it many different types of ama supposed are produced. . to go into further cannot be classified into metabolism, but they somehow jump HOW DOES THE PRODUCTION OF out of the normal metabolic cycle DISEASE OCCUR FROM BOTH AMA and work as harmful entities. In case AND FREE RADICALS? of ama, it is seen that ama is also an intermediary metabolite in the According to Susruta, a disease is produced process of digestion at different in six steps (kriyakala) viz. sancaya, levels and if the process is not prakopa, prasara, sthanasamsraya vyakti completed or ama remains as it is, it and bhedavastha. becomes harmful to body. 4. step. It happens due to impairment of agni metals also produce free radicals. at that place. Similar is the case with free Ama is also said to be produced from dravyas radicals, at certain site due to impairment in (poisonous action of free radical scavengers increased substances). Processes which are responsible for free production of free radicals takes place. radical When this sancaya or accumalation is in production are studied in detail in modern science. small amount it does not cause any harmful Auto-oxidation, effects, but if treatment is not given, this consequent inactivation of small sancaya exceeds the threshhold. Then it molecules such as reduced thiols and starts producing minimal symptoms, this is flavins, electron transfer etc. are few such processes. 5. the stage of prakopa (vitiation of dosas). [5] After this stage, ama goes into circulation; Total number of types of free radicals is In cases of diseases produced by ama, sancaya of ama is first Certain toxic substances like heavy visaja [13] still not same is the case with free radicals. Now this known. ama requires a site for creating disease in 23 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ form of khavaigunya, (pre-existing defect or understanding the phenomena involved at organ-tissue weakness) which should be the molecular level of ama. considered as weakness in any body tissue where ama may get CONCLUSION sthanasamsraya, (localization of lesion)or may adhere with On the tissue or cells. In case of free radicals concept with them. Therefore depending upon this of ama which supplies the the original source of the free radical organ-tissue weakness) different diseases theory." The above speculation leads to the are produced in different manner from same conclusion root cause, i.e. ama or free radicals. This is sthanasamsraya. found pathological basis of ayurveda is perhaps site of khavaigunya ,(pre-existing defect or of similarities ama one may say that "the all too-vital can easily take part in electron exchange stage of between the factors namely free radicals and also, they look for a site which is weak and the basis that the earlier ayurvedic concept of ama can be explained to the Now modern man by justifying it with the help of symptoms of diseases become clear. All biochemical parameter called free radicals. pathologies described in modern science are Free radical can be a future parameter to from this stage. In modern science stages measure the depth of pathology. earlier to this are rarely considered. After this stage pathology at gross level becomes REFERENCE visible. If even at this stage the disease is 1. Astanghrdayam of Vagbhata edited with the Vidyotini Hindi Commentary by Kaviraja Trideva Gupta edited by Yadunandana Upadhayaya. Chaukhambha Prakashan Varanasi. Edition 2011 Sutrasthana 13/25 Page No. 132 2. Caraka Samhita – of Agnivesa, revised by Caraka and Dradhabala with the Ayurveda – Dipika Commentary and with Vidyotini Hindi Commentary by Pt. Kasinatha Sastri. Chaukhambha Sanskrit Sansthan, Fourth edition 1994 . not treated it leads to complications which are described in ayurvedic classics as updravas (complications). From above discussion it becomes clear that the method of production of disease at its basic level is described in similar manner in modern as well as in ayurvedic literature. Free radical theory is one of the biggest clues which help us in 24 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Caraka Chikisthan 15/44 Page No. 386. 3. Madhava Nidanam of Sri Madhavakara with the Madhukosa Sanskrit Commentary by Srivijayraksita and Srikanthadatta,edited by Prof. Yadunandana Upadhayaya,Chaukhambha Sanskrit Bhawan Varanasi.edition 2003 Adhaya 25/1-5 Page No. 509 4. Charakasamhita of Agnivesa revised by Charaka and Dridhabala with the Ayurveda-Dipika Commentary of Chakrapanidatta edited by Vaidya Jadavaji Trikamji Acharaya. Chaukhambha Surbharati Prakashan 4th edition 1981( Reprint 2009) Chikisthan15/5, 15/15 Page No.512,514 5. Salvemini D and R Bottling,The effect of the Free radical scavangers on platelet adhesion and aggregation. Drug News and Perspective Ed. J.R. prous.J.R. prous,Science Publishers 3(4): 202212, 1990 Joel F Liebman and Joan Selverstone Valentine, Active Oxygen in biochemistry, Joan Selverstone Valentine, Christophers Foote, Arthur Greenberg, Joel F Liebman editors, Chapman and Hall, Madras; 1995. p. 1-37. 8. Niwa.Y. Effect of Maharishi-4 [MAK-4] and Maharishi-5 [MAK-5] on inflammatory mediators- with special reference to their free radical scavenging effect. Indian journal of Clinical Practice, 1991: 8(1):23-27 9. Robbins and Cotran Pathologic Basis of Disease, 7th ed. Elsevier. Chapter 1 Cell Injury, Cell Death and Adaptations pg 14-16 10. Text book of Medical Biochemistry - S. Ramakrishnan, K. G. Prasannan, R. Rajan, Orient Longman Ltd. Hyderabad (1986). 11. Methods in Enzymology. Volume 472, 2010, Pages 153–178. 12. Free radical Mediated Disease and Ayurveda (1996) Seminar at B.H.U. 13. Sushruta Samhita : Ayurveda tatva sandipika Hindi Commen. byAmbikadatta Shastri, 9th Edi. Chaukhambha Sanskrit Samsthana (1995).Surasthan 21/36 page no-94 6. Dr. Ingrid Naiman 2013 (for AAPNA conference on march 2013) 7. Biological Reactions of Dioxygen: An Introduction, Raymond YN Ho, Cite this article: AMA & FREE RADICAL THEORY Gaikwad Madhavi Dattatray Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2): 17-25 25 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_4 ______________________________________________________________________________________________________________________________________________________ EFFECT OF SOOKSHMA TRIPHALA IN POST OPERATIVE SURGICAL WOUND CARE W. S. R. TO WOUND FIBROSIS ___________________________________________________________________________ Shailendra D. Katakdound *1 ___________________________________________________________________________ 1. Associate Professor and Head, Strirog Prasutitantra Department, V.P.A .Medical College & Institute of Yoga, Sangli, Maharashtra. * Corrsponding Author: Email- [email protected], 9422472975. ___________________________________________________________________________ 15th post operative day. In Group-A wound ABSTRACT fibrosis decreases significantly on 15th post Effective use of Ayurvedic drug in operative day but in Group-B which was postoperative wound care in major surgical persist. Patients of both groups showed procedure is basic concept behind this similar relif in pain, local tenderness, clinical trial. For this study all patients are induration taken from study centre. Total 40 pts were in Group-B(n=20) difference treatment is equally effective in both groups Tab–Sookshama Triphala 1gm three times a while significant observed in wound fibrosis. Hence the included in study group; In Group-A(n=20) day but for pain, local tenderness & induration but Tab- on post operative wound fibrosis Group-A Seera(serratiopeptidase) 10mg two times a shows comparatively good result then day was given from 2nd to 15th postoperative Group-B. Study concluded that Sookshma day. In all patients wound dressing removed Triphala Vati is equally effective when rd on 3 post operative day to examine wound compared with modern drug in post th stitches were removed on 8 post operative operative wound care day. Assessment of wound done for gaping, & showed better result on post operative wound fibrosis. sokage, exudates & dehiscence on 3rd 8th & 26 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Hence Sookshma Trifala Vati is practically drugs, antibiotics are available to overcome reliable to use in post operative wound care these problems but analgesic & anti- to manage post operative pain & wound inflammatory drugs causes moderate to complications. severe gastritis. This affects appetite & diet of the patient. In post operative management Keywords: Post operative wound, & care proper diet is very important. In Sookshma Trifala Vati, Wound healing, Ayurveda wound fibrosis. Acharya Susruta described shasthiupkrama (60 measures) for surgical & non surgical wound care[1] . Ayurvedic INTRODUCTION: medicines are very useful to relive post operative Surgery is a definitive treatment for pain, induration, gaping , various organic diseases. Surgery can save excessive scar fibrosis without affecting life of patient in certain diseases where appetite of patient[2-5] . Instead of affecting medicine shows very little role. In modern appetite of patients these drugs enhances medicine surgical branch became very appetite which is very useful in post advanced due to many factors like advanced operative management. To minimize post anesthetic techniques, anesthetic drugs, operative wound complication & modern advanced surgical instrument & equipment , drug related side effects this study has been antibiotics, material, planned with aim to evaluate efficacy of advanced sterilization techniques, sterile ‘sookshma triphala vati’ for post surgical operation wound care. advanced theater & suture analgesic ,anti- inflammatory drugs . Hence morbidity & Materials & Methods: mortality rate decreases positively during and after surgery. In spite of all these Material: advances surgery related complications occurs in that wound related complication are common. In surgical 40 post operative (gynaecological & wound obstetric) patients were selected for this complications pain, infection, gaping, scar study. fibrosis, long standing scar tenderness are common complications. medicine analgesic, In modern anti-inflammatory 27 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Tab-Sookshma Triphala -250mg opened on 3rd post-operative day. Cleaning (Ayurved Rasashala Pune Batch no. 12544- of wound done & betadine ointment applied 13000), locally & no dressing done to observe Drug: wound & to see result of treatment. Tab-Sera10 mg (serratiopeptidase) all patients Pfannenstieal incision taken & Surgical wound examination done daily & result noted on 3rd, 8th & 15th post operative day as per subjective & objective parameter adopted f or this study. All skin sutures removed on 8th post-operative day discharged on same day. All patients from both groups were called for follow up on 15th post operative day to observe final result. abdomen closed layer wise with vicryl No- OBSERVATIONS AND RESULT Method: Post operative (gynaecological & obstetric) patients were selected from I.P.D. & divided into two groups. All patients were undergone for major surgical procedure..In 0. No sutures were taken to approximate subcute fat. Skin sutured with vertical To study the effect of Ayurvedic drug on mattress suture with Barbados no-60.In post operative wound care observation & Group-A(n=20) calculation according to following charts. Tab-Sookshma Triphala 1gm three times a day while In Group- After observing all data B(n=20) Tab- Sera(serratiopeptidase)10mg calculation are done to find out the two times a day was given from 2nd to 15th treatment is effective or not. All statistical post operative day. In both group Tab- calculations are done by applying ‘t’ test, Zerodal (Diclofenac sodium) was prescribed chi Square test and ‘t’ value is calculated to to all patients form 2nd post operative day up revel ‘P’ value to decide effectiveness of to two days. Surgical wound dressing treatment. The table showing post operative cases in both groups: Group Group-A(n=20) Group-B(n=20) Hyterectomy 13 LSCS 07 12 08 28 Total 20 20 statistical ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ The table showing the difference of difference in both groups. Prameter X1 X2 S.D.1 S.D.2 S.E. t P Pain 2.15 1.85 0.6708 0.4894 0.259 1.1583 >0.05 L. Tendrness 2.15 1.8 0.4894 0.5231 0.2265 1.545 >0.05 Induration 0.95 0.9 0.3940 0.6407 0.2314 0.2160 >0.05 Fibrosis -0.1 -0.7 0.3078 0.5712 0.1966 3.05 <0.05 Unpaired ‘t’ test used for the shows antibacterial action when given difference of difference in both groups for locally & orally[2-5]. Triphala also shows pain, local tenderness & induration ‘t’ value astringet, anti inflammatory & antiseptic is 1.1583, 1.545 & 0.2160 respectively & action ‘P’>0.05 which shows that there is no process[11]. statistical significance because both groups which acts as cementing material & required shows same effects on post operative pain in the process of blood clotting[8]. Triphala relif induration. hastens the process of phagocytosis[9] hence Unpaired ‘t’ test used for the difference of dead cells & debris are easily eliminated difference in both groups for fibrosis ‘t’ from wound[6-7]. Triphala increases blood value is 3.05 and ‘P’<0.05 which shows supply that there is statistical significance in both granulation tissue formation at wound[10]. local tenderness & so it hastens Triphala towards wound contains wound & healing collagen accelerates group on post operative wound fibrosis. Kajjali[12] is a khalvi rasayana[17] it acts as catalyst hence enhances absorption Discussion: of herbal pharmacological molecules so To Sookshm prove the triphala vati effectiveness [17-18] in of increases bioavailability injested drug[18]. post Drug effect is more after addition of kajjali operative wound care following objective so helpful in reducing doses of drug[13]. It parameters were taken i.e. local tenderness, binds with mucosal coat of GIT hence induration & fibrosis . Sookshm triphala vati[17] contains triphala churna kajjal[12]. Triphala[2] [2] produces pharmacological sustained release & of drug better crosses blood intestinal is rich in Vit-C it barrier[14]. It shows anti IgE mediated 29 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ reaction & scavenges circulating immune fibrosis Group-A showed comparatively complexes[15]. It shows immune enhancing good result then Group-B. effect, cellular rejuvinative effect, systemic detoxification &antioxidant effect[16]. Again Summary & Conclusion: it maintains half life of the herbal drug Study concluded that Sookshma molecules for longer period. Kajjali shows a Triphala Vati is equally effective when bacteriostatic & bactericidal action when compared with modern drug in post given orally[19-20] All these properties of operative wound care & showed better Sookshm triphala vati are utilized in the result on post operative wound fibrosis. management of post operative wound care. Hence Sookshma Trifala Vati is practically reliable to use in post operative wound care Result: to manage post operative pain & wound No gaping, soakage, any exudates, complications. dehiscence found at wound in any patient. All patients were called for follow up on References:- 15th post operative day. No tenderness, 1. Anonymous, Sushruta Samhita, ed. Acharya, J.T., Chaukhambha Orientalia, Varanasi., 1980. 2. Araujo Mohana Pinheiro, Cristhiane de AraujoTorres, J Surg Cl Res 2010, 1, 33-45. 3. Desai, H.K., “Chemical Investig. of some Indian Plants Part VII”, Indian J. of Chem. Vol. 11: 840 (1973). 4. Dhar M.L.et.al.,“Screening of Indian plants for biological activity” Part I, Indian J. of Expt. Biology, Vol. 6: 232 – 247 (1968). 5. Johanson D. A. Plant Microtechnique, Second edition Mcgrew Hill publishing Co., Ltd., (1939). 6. Kent Doi, Asada Leelahavanichkul, Peter S.T. Yuen, Robert A. Star, JClin Invest 2009, 119, 2868–28789. excessive wound fibrosis observed in any patient from study group. The wound fibrosis observed from 8th post operative day in both groups. In study group wound fibrosis decreases significantly on 15th post operative day but in control group which was persistent. This study shows that in both group similar findings were observed for pain, local tenderness, induration but significant difference observed in wound fibrosis & in study group no antiinflammatory used after 4th post operative day. Hence the treatment is equally effective in both groups for pain, local tenderness & induration but on post operative wound 30 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 7. KirtikarK.R.&BasuB.D.Indian Medicinal Plants Vol.1 – 4. II edition, Bishen Singh Mahendrapaul Singh, Dehradun (19185). 8. Nadkarni. K. M. Indian Materia Medica, Baptish Mission Press, Calcutta (1908). 9. Pandey G. S. & Chunekar K. S.: Bhavaprakasa Nighantu (Indian Materia Medica) Chowkhambha, Varanasi – 1 (1969). 10. Phadke, S.A., Kulkarni, S.D., Indian Journal of Medical Sciences 1989,43, 113-117. 11. Scott R. Hyde, Rex D. Stith, Mccallum R.E., Infection and Immunity1990, 619-624. 12. Tariq, M., Hussain, S.J., Asif, M., Jahan, M., Indian J Exp Biol 1977,15, 485–48. 13. Saper RB, Kales SN, Paquin J, Burns MJ, Eisenburg DMDavis RB, et al. Heavy metal content of ayurvedic herbal medicine products. J Am Med Assoc 2004; 292:2868– 2873. 14. Nissen N, Weidenhammer W, Schunder-Tatzber S, Johannessen H. Public health ethics for complementary and alternative medicine. Eur J Int Med 2013; 5:6267. 15. Ibrahim D, Froberg B, Wolf A, Rusyniak DE. Heavy Metal Poisoning: Clinical Presentations and Pathophysiology. Clin Lab Med 2006; 26: 67–97. 16. Narayanaswamy V. Origin and Development of Ayurveda. Anc Sci of Life 1981; 1:1-7. 17. Shastri K. Rasatarangini. 11th edition, Motilal Banarsidas, Ch. 2, Shlok 52, Pg. 22. 2009. 18. Shastri K. Rasatarangini. 11th edition, Motilal Banarsidas, Ch. 6, Shlok 107, Pg. 124. 2009. 19. Mitra A, Chakraborty S, Auddy B, Tripathi P, Sen S, Saha AV, et al. Evaluation of chemical constituents and free radical scavenging activity of Swarnbhasma (goldash), an Ayu. drug, J Ethnopharmacol 2002;80:147-153. 20. Kumar A, Nair AG, Reddy AV, Garg AN.Bhasmas: unique ayurvedic metallic-herbal preparations, chemical characterization. Biol Trace Elem Res 2006; 109:231–254. 21. Anonymous .WHO- Experiment committe on specification for pharmaceutical preparations. 32 reports (WHO, Geneva) 1992:44 and 75. Cite this article: EFFECT OF SOOKSHMA TRIPHALA IN POST OPERATIVE SURGICAL WOUND CARE WITH SPECIAL REFRENCE TO WOUND FIBROSIS Shailendra D. Katakdound Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2): 26-31 31 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_5 ______________________________________________________________________________________________________________________________________________________ CLINICAL EFFECT OF GOKSHUR POWDER, HONEY AND SHEEP MILK ON URINARY IN RENAL CALCULUS ________________________________________________________________ Rajesh Chandrakant Pandit*1 _______________________________________________________________ 1. Associate Professor, Surgery Dept., MAMC, LATUR, Maharashtra. * Corresponding Author: [email protected]; Cell : 9637465065 ________________________________________________________________ 3) Results: The stated research is having ABSTRACT: excellent results over all types of urinary 1) Objectives: As India is a tropical country, calculi including old and new cases and size there are multiple patients suffering from of calculi reduces gradually and finally Urinary calculi i.e. urolithiasis, and in passes of the calculi through the urinary modern practice there is no complete system. remedy except surgery for this. The purpose 4) Conclusion: Finally this research is very of my study is to assess the clinical efficacy of stated medicinal treatment much useful to the society suffering from over urinary calculi without undergoing to any urolithiasis by the sushruta. type of surgery and there is definite 2) Method: The process to give the stated conclusion about non recurrence of the medicine is completely under manual calculi again. supervision upto 7 days of treatment and follow up after 30, 45 and 60 days by the In Ayurveda under the heading of personal appointment with the patients with Ashmari all types of urolithiasis are their x-ray and USG Readings. described by Sushruta. There are many formulations 32 for the conservative ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ management of all kinds of Ashmari. Shodhan of body, Dietetic and behavioural Among these Ajaksheer (Milk of Sheep), ethics and Miscellaneous.[1] and Gokhsur are two also mentioned for Acharya treatment of ashmari. In this study these two urinary Gokshurbeej powder and 10 gm honey two times for 7 days. In control group infection in modern Today most of the urinary stones (n=30) only 100ml sheep milk was given need surgical intervention when there is two times a day for 7 days. Follow up was gross hydronephrosis due to obstructive done after 30 days, 45 days and 60 days recurrence. tract paralance.[2] given with 100ml sheep milk as anupan for the perineum and urethra which are similar like this purpose in trial group (n=30) 10gm treatment explained general of ashmari like pain at umbilicus, were tried in the patients of Ashmari. For after Vagbhat uropathy. There are some specific medicines Study internally, provided relief up to some certain concluded that trial group was found size of stones without hydronephrosis. effective to reduce the size of Ashmari as It is worthwhile to mention modern well as relief in the symptoms of Ashmari as aspect of urinary calculi which emphasizes compare to control group. the need of medicinal treatment up to the size of 6 mm (like forced dieresis, INTRODUCTION: hydrotherapy.) After that it needs surgical Ayurveda is an ancient Science of treatment. Some non invasive procedures life as old as human race. It has an ultimate like LASER therapy, ESWL, etc. are also aim indicated, but these are very expensive and to maintain health of healthy individuals and cure the diseased ones. also one cannot assure about the nonoccurrence of stone again. It is pertinent to give the reference of urinary calculi which has focused in In Ayurveda prominently. Sushruta Samhita the management of Ashmari is given by Sushruta is Gokshurbeej powder, and sheep Acharya Sushruta, Pioneer of milk as anupan for 7 day for complete sure surgery, aetiological factors for Mutraj of Ashmari. Considering these facts this Ashmari viz. Improper and inadequate study has been planned with aim to the 33 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ clinical effect of Gokshurbeej Churna, iii) Only those patients were selected in Honey and Aviksheer (Sheep Milk) in renal which USG and / or X – ray shows calculus. [3][4] presence of calculus in urinary tract. b) Rejection Criteria : MATERIALS AND METHODS: i) Patients above 60 years ii) Patients having any other major illness CLINICAL TRIALS: with calculus like HT, DM, Heart Disease etc. CRITERIA: iii) Unconscious patients. a) Selection Criteria : DRUG ADMINISTRATION: i) Age group within 0 to 60 years. ii) Without any complication in urinary tract like UTI, 60 patients were divided in two groups. 30 hydronephrosis, patients were selected in each group. hydroureter etc. a) Trial Group : 1. USG Abdomen, 2. Plain X – ray KUB after preparation. Sr. Drug No. Gokshur 1. beej Churna 2. Honey 3. Aviksheer Quan Administrati Durati tity on on 10 gm. Clinical Signs: Lehan B.D. 10 for 7 gm. days 100 ml. 1) Pain 2) Burning Micturition 3) Haematuria OBSERVATIONS: Anupan Generally teenagers of patients get relief than the elder one while males get more b) Control Group : Ony Aviksheer relief than the females. The occupations like (Sheep Milk) is continues seating or hardworking both are administered 100 ml. B.D. for 7 days. proven about the calculus and having the similar results. CRITERIA FOR THE ASSESSMENT OF CALCULI: TABLE NO. 1: Presentation of table & statistical data. 34 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Age in Relief Years Pain (%) (mm) D – 15 5 4-5 50 5-10 D – 1630 D – 3145 D – 4660 TABLE NO. 4 : UNPAIRED ‘t’ TEST in Reduction of size FOR SIZE OF CALCULUS Follow up S.E. ‘t’ 40 4-6 35 5-7 P 00 – 07 0.0 0.9 P>0.05 07 – 30 2.5 4.0 P<0.05 30 – 45 0.0 - 00 – 45 2.5 4.0 P<0.05 - TABLE NO. 2 : PAIN Follow up Day Medicinal Control Group Group DISCUSSION: X S.D. X S.D. Here we are giving honey as a Yogavahi th 2.9 0.3 1.3 0.5 dravya to increase the properties of Gokshur 7 th 2.4 0.6 1.3 0.5 and Aviksheer. 30th 1.1 0.7 1.6 0.5 45th 0.2 0.5 2.0 0.4 0 PAIN: TABLE NO. 3 : SIZE OF CALCULUS Follow up Day It markably reduced due to decreasing the size of calculus, while the Medicinal Control marginal ends of calculus becomes blunt, Group Group which were sharp before the treatment X S.D. X S.D. 0th 12.5 11.7 04.4 01.7 7 th 12.5 11.7 04.4 01.7 30th 04.7 04.9 06.4 02.1 45th 04.7 04.9 06.4 02.1 started which can be seen in USG. BURING MICTURATATION: It is also reduced as Gokshur is diuretic i.e. Mutral and flashes the urine outside the system by increasing the volume the urine. It results into decreases acitic PH of the urine. 35 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ From above vivid discussion study concluded that Gokshurbeej Churna, Honey and Aviksheer (Sheep Milk) was found effective to reduce the size of Ashmari as well as relief in the symptoms of renal calculus. HEMATURIA: It also get reduced due to the dissolving of the sharpness of the stone with Aviksheer and Gokshur. Here we are giving honey as a Yogavahi dravya to increase the properties of Gokshur and Aviksheer. ACKNOWLEDGEMENT: While treatment process of stated study no complications were noticed. Author thanks to Dr. M. J. Quadri and Dr. S. V. Annapure for their guidance throughout the study. ANALYSIS: REFERENCES: Though the above all parameters were considered for the assessment but notable changes were observed in above two criteria i.e. size of calculus and pain. 1. Vd.Yadavji Trikamji, Sushruta Samhita Dalhan Tika, part 2, Chikitasasthana, chapter no.1/8, 4th edition, Chaukhamba Orientliya, Varanasi, 1980 2. Astanga Samgraha of Vagbhata, part II, Translated by Prof. K.R. Srikantha Murthy, Published by Chaukhambha orientalia, 3rd Edition 2001 3. A HAND BOOK OF DRAVYAGUNA. Prof. J. K. OJHA. Page no. 29, Chaukhamba Sanskrit Pratishthan, Varanasi, 1995. 4. Lt. Col. K. R. Kivtikar and Maj. B. D. Basu , INDIAN MEDICINAL PLANTS, Chaukhamba Sanskrit Pratishthan, Varanasi, 2005 From the above observation we can state that the size of calculus is reduced up to 4 to 5 mm in 30 days. Pain is also reduced from 3+ to 1+ or 0 (Zero). Burning micturition and haematuria is also considerably reduced. This reduced signs and symptoms are statistically significant. CONCLUSION: Cite this article: THE ROLE OF GOKSHURBEEJ CHURNA, HONEY AND AVIKSHEER (SHEEP MILK) ON URINARY CALCULUS Rajesh Chandrakant Pandit Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):32-36 36 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_6 ______________________________________________________________________________________________________________________________________________________ To assess the Amalaki Rasayan effect in Geriatric problems ___________________________________________________________________________ Vanita N. Puri*1 __________________________________________________________________________ 1. Associate Professor, Department of Swasthavritta, C.S.M.S.S. Ayurved College, Kanchanwadi, Aurangabad. (431002). * Corresponding Author: E.mail : - [email protected] Mob. No. 9096890140 ___________________________________________________________________________ Dinacharya, Rutucharya & also through Abstract: some chikitsa which promotes strength & In routine practice we came across immunity mostly included in “Rasayan with so many patients among which Chikitsa”. [1] Ageing is general response that geriatrics group is the major class. The produces observable changes in structure & ageing process or growing age can’t be function due to environmental stress & avoided but it can be delayed at least we can disease as well as changes in diurnal habits. try to treat the changes. Modern medicine Ayurveda has emphasis on prevention. treatment fails to give permanent relief from Rasayan Chikitsa has got its importance on above symptoms completely but Ayurveda preventing the disease to keep healthy to all may satisfactory answer for this that is living individuals. Rasayan Chikitsa is “Rasayan Chikitsa” . probably promising answer for geriatric problems & the drug which is chosen for Keywords :-Rasayan, amalaki, geriatrics.. this is Amalaki. natural Introduction: source bioflavonoids, Ayurveda is a science of life & has carotenoids[5] described how to live a healthy age through 37 [2] Amalaki is the richest of flavones viramin ‘C’, polyphenols ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Group II –Treated with sharkara The antioxidant effect of Amalaki is significantly greater than that of vitamin Selection of Patients: ‘C’. The patients who form the materials Aims&Objectives: of present clinical study will be selected The present research work has been from vrudhashrama, Tapovan, Panchavati, under taken with the following aims & Nasik as there are no. of senior citizens objectives. which lived together it was possible for me to get all cases under one roof. 1) To study the pathogenesis of geriatrics & to corelated it with Criteria for Selection of Patients: modern science. The patients were selected for study as per 2) To assess the effect of amalaki rasayan in specially geriatric following norms: problems joint pain, a) Criteria for inclusion: Inactivity,Kshudha Maudhy[4],Nidranash[5] 3) To introduce an easily available economically cheap & Age group: above 50-70 Years Sex : Both male & female. Patients having following signs much & symptoms ( joint pain / effective drug for the geriatric Inactivity / Kshudha (Maudhya)/ problems. Nidra (nash). Materials & Methods: Criteria for Exclusion of patients Total 60 patients randomly selected & studied. These patients were selected into 2 groups each consisting of 30 patients. The patients were treated for 90 days. Persons below 50 yrs of age Persons suffering from diabetes , Hypertension are excluded from Group I – Treated with Amalaki Churna & present clinical trials. sharkara Objective Parameters: 38 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Criteria for assessment day patient was thoroughly examined & recording pulse, BP, systemic examination 1. Joint Pain 2. Inactivity done. Patients were called for the five visit. on 1st, 7th, 15th, 30th, 90th days. Follow up (Knee joint) +++ Severe +++ Severe ++ Moderate ++ Moderate + Mild + Mild 0 Nil 0 Nil 3. Kshudha 4. Nidra +++ Severe +++ Severe ++ Moderate ++ Moderate + Mild + Mild 0 Nil 0 Nil sheet was filled with careful observation & examination effect of the drug on each symptom of all patients was recorded in each case pro-forma with follow up chart for assessment of effectiveness of the drug questionnaire has been framed & given to the patient twice before & after treatment. I have also attached the permission letter of the manager of Elder homes written concern of each patient in my present work. Follow up Chart of Sign & Symptom: Before Drug Dose: After T/t Amalaki Churna with sharkara 4gm T/t twice a day Ist (Ist IInd day) IIIrd Iv Vth (7th (14 (30 (90 day) day) day) day) 1) Sharakara 4gm twice a day Duration of Study: 90 days A pro-forma of case sheet was Anupana : luke warm water. prepared. Patients were subjected to detail history taking & clinical examination 1st Observations: 1) Joint Pain : Cure Complete Moderate Mild Total Grade 27 1 2 30 Group I 39 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Group II Total 18 4 8 30 45 5 10 60 ‘t’ Calculated > to = 8.69 t table = 5.99 This means amalaki Rasayana is more effective in treating joint pain. 2) Kshudha : Cure Grade Group I Group II Total Complete 27 18 45 Moderate 1 4 5 Mild 2 8 10 Total 30 30 60 Mild 4 8 12 Total 26 26 52 ‘t’ calculated = 8.69 > t table = 5.99 This means Amalaki declines kshudha mandhya 3) Inactivity : Cure Grade Group I Group II Total T = calculated 5.99 reducing inactivity. Complete 12 6 18 Moderate 10 12 22 > t table = 3.514 thus the treatment is significantly effective in 4) Nidra : Cure Grade Group I Group II Total Complete 22 10 32 Moderate 0 8 8 T calculated = 15.18 > t table = 5.99 40 Mild 1 5 6 Total 23 23 46 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Amalaki find more effective in treatment of Geriatric problems Nidra Nash. concern with the symptoms like inactivity, joint pain, Observation: kshudhamandhya & nidra nash[3] 2) From socioeconomic view There is reduction in symptoms concerned drug ‘Amalaki Churna’ is after 4th follow up in Group I patients easy to perform palatable easily compare to II group. At the end of 90 days, available, cheap which gives prompt the patients of Group I show significant symptomatic relief to the patient. improvement in the symptoms like 3) In geriatric problems the measurable inactivity, joint pain kshudha (hungryness) condition of the patient as disability & nidra (sleep). to perform even the routine work this disability can be conquered by Discussion : - Rasayan Chikitsa & the patient is in Amalaki Churna administred in position to perform his regular Geniatric patients might got the results by activities. virtue of its Rasayan properties. As it is the 4) These results of Rasayan Chikitsa highest source of vit c , it acts as the are encouraging & with this much antioxidant it protects cells against free study it can be said that further radical damage preventing ageing process. research is necessary. Hence when it improves immunity it gives References: resistance to fight the geriatric symptoms more effectively & positively. 1. Agnivesh Charak Charak Conclusion: Samhita chandrika with Hindi Commentary by Dr. Brahmahanand After reviewing the whole dissertation work Tripathi and Dr prabhakar Janardan in nutshell following conclusion may given. Deshpande Chikitsa Stana Chapter 01 1) The result of clinical trial itself is a Verse no.07 Chaukhamba proof to say that Rasayan Chikitsa Prakashan,1998. has definite role in systemic 41 page 05 Surbharati ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 2. Raj Nighantu, Endradev Tripathi, 4. Susrut Samhita with Ayured-tattva Amdradivarga, verse no. 158, page Sandipika Hindi Commentary by no Kaviraja Ambikadutta Shastri and 371 Chaukhamba Krunadas Akadami,Varanasi. 3. Bhel Samhita Pranajivana Manekchanda Mehata Vd.Visarada Sutrasthana Chapter 1 Verse no.22 V.S.Venkatasubramania Sastri and page no.04 Chaukhamba Sanskrit Vd. Visarada C. Raja Rajeswara Santhan, Varanasi 2003. Sarma Nidansthana verse no.02, 5. http: page no.140 Literary Research Unit TMSSM Thanjavur,CCRIMH-New //www ayurveda- foryou.com>ayurveda-herb/amalaki Library 6. Indian Medicinal Plants Vol –lll by Delhi K. R. Kirtikar and Basu page 1977. no.2220 published by lalit Mohan Basu, Allahabad 1998. Cite this article: To assess the amalaki Rasayan effect in geriatric problems Vanita N. Puri Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):37-42 42 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_7 ______________________________________________________________________________________________________________________________________________________ Case Report of Ligament & Menisceal Tear Of Knee Joint ___________________________________________________________________________ Gayatri B.Pund* 1, Raman R. Ghungaralekar 2 ___________________________________________________________________________ 1. 3rd year P.G.Scholar, Kayachikitsa Dept. 2. H.O.D. and Professor, Kayachikitsa Dept, R. A. Podar Medical College, Worli, Mumbai. *Corresponding Author: [email protected] ___________________________________________________________________________ Here is a case reported which is Abstract : successfully Ligament tear is most common in treated with ayurvedic management. A combination of abhyantar atheiletics and also seen in old age people. chikitsa and bahya chikitsa(Utkarika) was Traumatic injury can worsen joints in old beneficial in relief of symptoms.So it can be age whose joints are already degenerated. said ayurvdic therapy can have a role in management of Knee joint ligament tear. Patient come with complaints of severe pain, tenderness, swelling at knee Key joint and difficulty in walking. According to words – Knee joint, ligament tear,Utkarika.) grades of sprain of ligament and occupation of the patient, treatment is decided. Anti- Introduction : inflammatory, analgesics, knee braces, rest, Knee joint is the largest joint in the physiotherapy can be considered. But a body and one of the most complex joint. It sport person will have to recover from it is also vital to movement. Knee ligaments fast. So surgery advised in severe cases, it is connect thigh bone to your lower leg bones. of doubtful benefit sometimes. Knee ligament sprains or tears are common 43 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ sports injuries. Although ligament tear is relief , treatment was continued for 1 common in athletes, it is also seen in old age month. He got 75% relief. From above case, people. we can say Ayurveda can have role in treating Knee joint ligament tear. In old age, already there is dhatu kshaya, degenerative changes occur in the Case Report : body. Even a healthy person can get, ligament tear from small injury. A 60 Years old male patient of anup desha So with kapha prakriti consulted at OPD of traumatic injury can worsen joints of old Kayachikitsa dept. with complaints of - age people whose joints are already degenerated. Chief complaints: Following symptoms are developed in patient since 4 yrs & these are In modern medicine, depending on increased from 6 months. occupation, age of patient and grade of tear, the treatment is decided. Sport person with 1. Lt knee joint pain & swelling severe injury, surgery is advised. Surgery success is in doubt sometimes. Also, patient 2. Pain increases on walking contraindicated to surgery, non willing for it the treatment is 3. Heaviness in left knee joint anti-inflammatory, analgesics, rest, physiotherapy, knee joint The patient was apparently alright before 4 braces. But symptoms not relieved fully. yrs, then he had trauma to his left knee joint. He had swelling & pain at that joint. He In Aurvedic point of view, it can consulted at orthopaedician who advised correlated as Sandhigat vata. Dah-swedaupnahanam Ayurveda. is the With chikitsa that, vardhakya awastha, vyadiavastha was Ayurvedic principles, stated asthi him in (total knee joint the same ,hence came in podar hospital to bharadhikya, the patient TKR replacement).The patient was not willing for kshaya, considered. to take ayurvedic treatment. He also took Using ozone therapy. His symptoms aggravated was since 6 months. treated. Internally, he was given asthidhatu balya chikitsa and locally doshpachak lepa Family history: NAD & then Utkarika. Within a week he got mild 44 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ K/C/O: HTn since 3 years under treatment 1)Asthivaha: Lt knee joint pain T.Amlo AT 1 OD. 2) Majjavaha: Past history: Accidental trauma to left knee Sandhi Parikshana (Joint examination) joint, 4 years back. Patient hitted on the Lt knee joint : door accidentally. i) Crepitus: Addiction: occasional alcoholism, smoking ii) Swelling: iii) Girth: Samanya Parikshana: Nadi: 72/min regular Agni: Tikshnagni Akruti: Sthool RR: 18/min i. Restriction of movements(karmagraha): Mala: Malavashtambha Flexion & extension painful Prakruti: Kapha pradhan vatanubandhi Investigations: BP: 130/80 mm of Hg X ray Knee joint (10/06/2013) severe space reduction in medial compartment of left Mutra: Samyak knee joint with marginal osteophytes. weight: 100 kg MRI Lt knee joint (12/06/2013): extrusion Koshth: Krur of medial meniscus with complex grade III tear involving the body & posterior horn of Jivha: Alpa saam the medial meniscus. Strotas Parikshana: Grade III tear of the medial collateral ligament. All the strotas within normal limit except 45 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Grade II sprain of the anterior cruciate (asthi, snayu, shleshak kapha kshaya) ligament. sandhisthanirukshata,kharata, saushirya sandhiatopa,Vatapurnadrutisparsha, Grade I sprain of the posterior cruciate sandhishoola Sandhigata vata ligament. Chikitsa[3]: Partial tear of popliteus muscle. सन्तिसम्प्प्राप्िे कुया्ि ् ववचक्षर्:। Severe changes of osteoarthritis involving the knee joint with the medial compartment affected to a greater extent. स्वेदोपनाहसुंमद् स्नेहाददक्रम:॥ CBC, ESR, LFT, RFT, Lipid profile, BSL: योगरतनाकर, WNL वािव्यािीचचककतसा, स्नायस ु त्यन्स्थगिे १/१ Samprapti[1][2]: Treatment Given : हन्तिसन्तिगि: सन्तिन ् शूल आटोपौ करोति च । Panchakarma chikitsa : सु.तन.१/२८ 1) Bhadranimbkulthadi Basti वािपर् ू ्् दृतिस्पश्: शोथ: सन्तिगिेतनले । प्रसारर्ाकुंु चनयो: प्रवन्ृ तिश्च सवेदना 350ml for 14 days(in sama awastha) 2) Pachatiktaghrutaksheer Basti ॥ 100ml for 14 days(in niram awastha) च.चच.२८/३७ Basti Nirman : Hetu: Sanniprakrushta: trauma to lt knee Poorva karma joint snayu cheda & kandara cheda saurambha karmagraha sandhishoth, Viprakrushta Krutashouchvidhi, on empty stomach for shool, : niruha. Sthaulya After food continuous pressure on knee joints & old ghrutaksheerbasti. age (vardhakya) sthanik dhatukshaya Sthanik snehan swedan 46 for Panchatikta ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Pradhan karma : Basti was prepared as Basti made by classical text methods with mentioned in our classical texts. help of these contents.Around 120 ml basti 1) Bhadranimbkulthadi basti Madhu is given. Paschhat karma : 20 ml Tadan karma is done for 30 min. Patient is Saindhava, yavkshar each 2 gm Sarshap tail & til tail each 15 ml Kalka advised to take rest. Eating allowed after ½ her. Pathya-apathya : Patient is advised to take light, ushna, laghu (kushtha,musta,pippali,shunthi) food. Avoid ativyayam, vegdharan, jagaran, 10 gm diwaswap. Bhadranimbkulthadi kwath (Nimba, Bahyachikitsa : kulattha, patha, arka, guduch, kantakari, aragvadhasiddha) Utakarika 300ml is a paste of masha churna, crushed seeds of til & atasi processed in decoction of bala & dashmula. respectively & are mixed into each other to It is heated & warm paste is applied at form homogenous mixture. Gomutra is then 400ml basti is given. It ashwagandha, yashtimadhu, mansakalka, All these contents are added one by one added to it around 30ml. Around 350 to lepa: affected joints, This is kept for 2-3hrs. Abhyantar chikitsa : following drug are given with lukewarm water (Koshn jal) 2) Panchtiktaghrutaksheerbasti – 1) Lakshaadi guggula 2 TDS 2) Apatarpana Kwatha 30 ml BD 3) Tb.Shallaki Fort 2 TDS 4) Tb.Nucort OA 2 BD Madhu 10ml Saindhava 2gm Panchatiktaghrut 20ml Panchatikta ksheerpak 100ml Discussion : (Panchatikta is Nimb, vasa, patol, guduchi, kantakari) 47 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Ligament & menisceal tear is not directly guggula contains laksha, asthisanharaka, stated in ayurveda. So, it was correlated arjunatvaka, ashvagandha, nagabalamool, with sandhigat vata. According to sam & guggul. It is asthisandhankar, asthibalya. niram avastha, it was treated & patient got Chingati helps in repairment of hyaline relief. cartilage & strengthens Panchatiktaghrutaksheerbasti 1)Sarvadehik chikitsa: ligament. Panchatikta improve asthi dhatvagni. Ghruta &milk provide vit D which help in calcium There are two causes of osteoarthritis & absorption & help in asthiposhana. ligament tear in this patient, we have to treat both causes i.e.sthaulya & local trauma. The 2) Sthanik chikitsa: treatment is divided in two stages. i.e. Knee caps with hinges. A)Samavastha B)Niramavastha. A) Chikitsa in aamavastha:(shoth) A. Chikitsa in Samavastha: (Sarvadehik doshpachanartha) Dashangalepa(It contains virya,tikta,madhur,kashay Aptarpan kwath contents musta, argvadha, ushna rasatmaka dravya.Thus help in dravashoshana & patha, karnja, devdaru, shunthi, khadir. It is asthisandhana) It was given for 6days. a combination of pachaniya, lekhaniya dravyas & help in strotashodhana. Kwath & B) Chikitsa in niramavastha: bhadranimbkulthadi basti was given to reduce weight. Shallaki, guggul उतकाररका इतयाददभि: उपनाहनम ् |[4] are saurambhnashak, shothnashak & vedanahar. Bhadranimbkulthadi pachana, lekhan, basti is medovilayana. Utkarika contains madhur rasatmaka & snigdha gunatamaka dravya.They nourishes ligaments,bones,sandhistha shleshaka kapha.Thus being lipophilic, utkarika dravyas are absorbed through skin.In this patient utkarika was given for around 1 month which gave excellent results.Within 3-4 days patient got relief in pain,difficulty in walking. deepan, Sama lakshane are reduced. B. Chikitsa in niramavasth(Asthi balya) After eliminating samata, asthi dhatu balya, sandhankar chikitsa is given. Laksha 48 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Yadavaji LAKSHANIK UPASHAYA: Symptoms 1.Sandhishool 2.Gamane prasangi shool 3.Sandhigraha 4.can climb up &get down on stairs 5.Sandhiaatopa Trikamaji Aacharya Commentary Chaukhamba Series, BT AT Not possible at all Can climb up 15 stairs Varanasi Nidansthana1/28 page no.261. 2. Charak Samhita With Ayurved Dipika Commentary Chaukhamba Sanskrit Series, Yadavaji swelling reduced by aaprox.2.5 cm in dimension Varanasi Trikamaji by Aacharya, Chikitsa Sthan 28/ 37 page no. 618. 3. Yogratnakar With Vidyotani Commentary Chaukhamba Sanskrit Series, Varanasi by Vd.Shri.Laxmipati Conclusion : Shastri,Vatavyadhichikitsa, 1/1 page Thus from above case study, we can no.517. confidently say that, knee joint ligament tear 4. Sushrut Samhita & menisceal tear has a good ayurvedic Nibandhasangraha treatment. Yadavaji With Edited Trikamaji By Aacharya Commentary Chaukhamba Series, References : Varanasi chikisasthana 32/12 page 1. Sushrut Samhita Nibandhasangraha Edited no.513. With By Cite this article: Case Report of Ligament & Menisceal Tear Of Knee Joint Gayatri B.Pund, Raman R. Ghungaralekar Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):43-49 49 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_8 ______________________________________________________________________________________________________________________________________________________ CLINICAL STUDY OF LAGHUSUTASHEKHAR ON AMLAPITTA ________________________________________________________________________ Prafull S. Yashwantrao*1, Minal Vaidya2 _________________________________________________________________________ 1. M. D. (Sch.) final year, Kayachikitsa, 2. H. O. D. & Prof. Kayachikitsa Y.M.T. Ayurvedic college & hosp. Kharghar, Navi Mumbai, Maharashtra ___________________________________________________________________________ Disease and sufferings have become Abstract:- fundamental attributes of human beings A total of 20 patients of Amlapitta were selected for the clinical since time immemorial. Due to urbanisation study. and change of life style people are inviting Laghusutashekhar was given to all of them many health problems, Amlapitta being one having, hyperacidity. The patients were among them. It is a very common disease mainly A affecting almost all the human beings in symptomatic improvement was observed in more or less severity. Increased pace of life, the of stress as well as changes in food and food Laghusutashekhar were given to each habits has been contributed to the increased patient in 3 doses for duration of 6 weeks. incidence Effect was assessed in terms of clinical described this diseases as it is produced by symptomatolgy. vitiated Pitta.[1] of Urdhvaga patients. Two Amlapitta. tablets Key words: Laghusutashekhar, Amlapitt, of Amlapitta. Charakacharya mçbmç=p³çcççvçb çÆHçÊçívç oçnb lç=<Cççb cçáKççcç³ççvçd ~ hyperacidity pçvç³çl³çcuççÆHçÊçb ®ç çÆHçÊçpççb½ççHçjçvçd içoçvçd ~~ INTRODUCTION:(®ç.çÆ®ç. 15/ 47) 50 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Amlapitta disease had first time INCLUSION CRITERIA described in details in separate chapter by Diagnosed cases of Amlapitta of Madhav Nidan. He mentioned the causes, types, pathogenesis, sign and symptoms of both the sexes in the age group of 18 to 58 Amlapitta[2] years EXCLUSIVE CRITERIA Laghusutashekhar is the drug which is having property of agni Pradipan and Pitta The patients who are known cases of - Shaman. [3] 1. Peptic ulcers AIMS & OBJECTIVES: 2. Duodenal ulcer To study the effect 3. Diabetes Mellitus of 4. Tuberculosis Laghusutashekhar in Amlapitta 5. Ca oesophagus MATERIALS AND METHOD:- 6. Chronic Smokers 7. Alcoholic patients 1. In clinical trial 20 patients of Amlapitta 8. Pregnant women were selected with hyperacidity of either sex, age group 16-60yrs. Patients were OBSERVATION: diagnosed and selected from the OPD and After giving drug to 20 patients for 6 IPD of Kayachikitsa of YMT college weeks, following symptomatic improvement kharghar. was observed. 2. Two tablets of Laghusutashekhar of 250 mg each with warm water was given in 3 doses Age:- for 6 weeks in 3 follow ups of two weeks. 3. An informed written consent of all patients Sr.no. Age No.of pt Percentage included in trial in the language best 1 18-28 6 30 understood by them was taken before 2 29-38 9 45 entering them in the trial. 3 39-48 3 15 4 49-58 2 10 4. Study centre:-Y.M.T. Ayurved Medical college, Kharghar,Navi Mumbai 51 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Diet:- Epigastric Pain:- Sr. No. Diet No. of pt Percentage 1 Veg 8 2 Non-veg 12 BT AT 40 Mean 2.200 0.600 60 SD 0.768 0.754 SE 0.172 0.169 Occupation:- t-score 6.025 Sr. No. Occupation No of pt % Dyspepsia:- 1 Labour 8 40 2 Clerk 4 20 3 Students 3 15 Mean 2.133 0.867 4 Teacher 2 10 SD 0.834 0.640 5 House wife 3 15 SE 0.215 0.165 BT AT t-score 4.750 Symptoms:Nausea:Sr. symptoms no. Before After treatment treatment % BT AT 1 Amla Udgar 20 12 60 Mean 2.000 0.545 2 Epigastric 20 11 55 SD 0.894 0.688 SE 0.270 0.207 pain 3 Dyspepsia 15 5 33.33 4 Nausea 11 6 54.54 5 Constipation 6 6 100 t-score 5.164 Constipation:- Amla Udgar BT AT Mean 2.700 0.500 SD 0.470 0.688 SE 0.105 0.154 BT AT Mean 1 0 SD 0 0 SE 0 0 t-score +inf t-score 9.314 DISCUSSION:52 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ In Amlapitta, due to nidanasevana 3. After the treatment of Laghusutashekhar 12 dravaguna of pitta increases which leads to patients got complete relief from Amla agnimandya there by ingested food becomes Udgar vidagdha and finally the symptoms like 4. Out of 20 patients 11 got relief from Amlodgara,Urovidaha, Aruchi etc. are epigastric pain. evident clinically. Laghusutashekhar has 5. 5 containts – shuddha swarna gairik (1 part), shunti(1 part) and has bhavana patients got complete relief from dyspepsia. of 6. 11 patients had Nausea out of them 6 got nagvallipatra swaras. complete relief 7. 6 patients had constipation and all of them 1. Swarna gairik[4] - kashay-madhur/ sheet virya /madhur vipak. Pruthvi+ Jal got complete relief 8. From this study it is reviled that there is mahabhut. Its is snighdha in nature. significantly reduction in symptoms of It acts as dravashoshak and pittashamak Amlapitta with use of Laghusutashekhar [4] 2. Shunti :- ;i.e. amla udgar, epigastric pain, nausea, Katu/ ushna virya/ madhur vipak. Angni+ Vayu mahabhut. constipation. 9. Laghusutashekhar has effective in treatment It acts as aamapachana and agni vardhana. of Amlapitta. 3. Nagavalli[4]:Katu-tikt / ushna virya / katu vipak. Agni+ Summery:- Vayu mahabhut. 20 patients of Amlapitta taken for It acts as deepana, pachna and kapha the study. These patients are assessed for kshalana treatment with various symptoms like Amla udgar, epigasric pain, nausea, dyspepsia, Conclusion:- constipation. The of Laghusutashekhar in 1. From the above study incidence of Amlapitta shows significantly reduction in Amlapitta observed more(45%) in age group symptoms. 29-38. This shows that Laghusutashekhar is effective drug against 2. Prevalence of Amlapitta is found in non- the Amlapitta. The mode of action of the vegitarian group(60%). drug is not clear as such. It needs a further study. 53 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 3. Bhavprakash Reference: Nighantu-of Sribhavmishra Edited with Vidyodini 1. Charaka Samhita, P. V. Sharma, Hindi Commentary Shri Brahmasankara Chaukhambha Orientalia, Varanasi 8 th Misra & Shri Edi, 2003. 2. Madhav Rupalalaji Vaisya 9th Edition Chaukhamba Sanskrit Sansthan, Nidan- Part nd –II , Varanasi, Haritakyadi Varga 7/34, pp 3- Yadunanadan Upadhyay, Choukhamba 9 th Sankrit Sansthan, Varanasi, 21 Edition, 4. Dravyaguna Vijnana; Vol. 2; Prof. 1993. page No. 170-71 Priyavat Sharma; Chaukhamba Bharati Academy; Varanasi; Reprint; 2000 Cite this article: CLINICAL STUDY OF LAGHUSUTASHEKHAR ON AMLAPITTA Prafull S. Yashwantrao, Minal Vaidya Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):50-54 54 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_9 ______________________________________________________________________________________________________________________________________________________ Effect of Praval Bhasma on Diabetic Neuropathy ___________________________________________________________________________ Komal S.Raut1 B.D. Gharjare2 ___________________________________________________________________________ 1. Final year MD kayachikitsa, 2. Professor, Kayachikitsa Dept. YMT Ayurvedic medical college, Kharghar,Navi Mumbai ___________________________________________________________________________ Introduction as Purvarupa of Prameha.[2] Daha is also described Diabetic neuropathy is a relatively early and common complication the Upadravas(complications) of Prameha. affecting These are very common features of diabetic approximately 30% of diabetic patients. Although the invention of insulin and hypoglycemic have done a great service for solution [1] complications . for their The used there is Dosha in Ayurvedic involvement diabetic amla rasa, sheeta veerya and Madhur vipaka which symptoms and moreover they have certain pacifies vata and pitta[3]. A preliminary study has been started to side effects. Therefore it is necessary to observe and evaluate the effect of Praval explore the possibilities of safer and bhasma on diabetic neuropathy in YMT effective treatments from other sources. In classics principles, to which is having properties like Madhur, conventionally are mostly for relief in the Ayurvedic According neuropathy. praval bhasma is a medicine neuropathic drugs neuropathy. of Vata and Pitta diabetics, yet these patients do not get a proper among Ayurvedic hospital, Kharghar symptoms like Suptata (numbness) and Daha (burning Key words: Diabetic Neuropathy, Praval sensation) in body parts especially in hands bhasma, Prameh, Dah, Suptata and feet are described 55 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Aims and objectives Plan of the treatment To study the effect of Praval Bhasma on The patients have been treated in OPD as diabetic neuropathy. well as in IPD depending on the severity To observe the safety of the treatment. and the circumstances. Materials and Methods patients have been treated cup of milk. the with Praval Bhasma 1 gThrice a day with 1 Inclusion criteria for the patients All Duration of the study was 30 days. The patients for this study have been Total 33 patients have been taken for the selected randomly irrespective of their age, study presently; however, the study is sex, religion, etc. continued. Patients with clinical positive history of type Criteria for assessment 2 diabetes mellitus having the symptoms of diabetic neuropathy (peripheral) are selected Neuropathy analyzer which is specifically for the present study. designed electronic machine by Diabetic foot care India, Chennai, can record the Exclusion criteria for the patients perceptions of vibration, heat and cold Patients having any other associated clinical sensations exactly with the help of computer conditions have not been included in the has been used to record these sensations present study. before and after the treatment in all the 33 Patients having diabetic complications other patients. than neuropathy were also excluded from The criteria used to evaluate vibration, heat the study. and cold sensations by neuropathy analyzer are as below [Table 1]: 56 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Table 1 : Criteria used by neuropathy record perception of cold sensation and analyzer machine to assess perception of temperature of the probe is to be increased sensations from 30°C up to 50°C to record perception of heat sensations. During the recording frequency of vibrating probe (which is to be kept in contact with All the symptoms have also been assessed the skin of the sole) is to be increased and before and after treatment according to the when patient feels the vibration it is given score recorded in the computer, temperature of the Table 2. probe is to be reduced from 30°C to 0°C to 57 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Table 2: Scoring of symptoms opiates, membrane stabilizers and antioxidants are used in diabetic peripheral Results and Discussion: polyneuropathy for symptomatic relief. All these drugs have their side effects. Hence None of the patients have shown any there is need to find out safer and effective new and unusual features during the course treatment from the sources other than of treatment. As we know that diabetic neuropathy is common conventional medicine. complication amongst diabetics. In conventional medicine tricyclic antidepressants, anticonvulsants, 58 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ According to Ayurvedic principles, right foot and 23% in left foot, which has the symptoms of diabetic neuropathy like come in to the normal range after treatment. paraesthesiae, pain and tingling sensation Improvement are indicating involvement of Vata Dosa. sensations are highly significant in both the Whereas burning sensation is because of feet. vitiation improved by 6.85% in right foot and it is of Pitta Dosa. Hence drugs in vibration Perception of heat significant and cold sensation is pacifying Vata and Pitta Dosas are useful in highly the treatment of diabetic neuropathy. praval improvement bhasma is a medicine which is having significant. It has come in to mild from properties like Madhur,amla rasa, sheeta upper range of moderate affection. in left whereas 3.9% foot it and is veerya and Madhur vipaka which pacifies vata and pitta. The most common signs found in diabetic sensory polyneuropathy are Sensat Mean ions B. A. T T 22 15 diminished perception of vibration sensation and impairment of all other modalities of Vibrat sensations. Perception of vibration, heat and ion cold sensations are recorded with the help of fr/sec neuropathy Cold analyzer before and after treatment in all the 33 patients of diabetic Hot neuropathy. Analysis of the results has shown highly significant to significant improvement in perception of S. S. t p % D E 31. 8. 1. 4. <0. 16 74 5 55 001 17 22 19. 5. 0. 4. <0. .8 .2 73 14 89 89 001 47 44 6.8 3. 0. 4. <0. .7 .4 5 99 69 69 001 these sensations. Table 3: Change in perception of sensations Table 3 and 4 show that perception in right leg of vibration sensations has been improved by 31% in right foot and 32% in left foot Sensat Mean and it came in lower range of moderate ions B. A. T T affection from severe. Perception of cold sensation has been improved by 19.7% in 59 % S. S. D E t p ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Vibrat 24 16 ion 32. 8. 1. 5. <0. Table 4: Change in perception of sensations 61 76 52 09 001 in left leg fr/sec Cold Hot 17 23 23. 6. 1. 4. <0. .8 .1 12 48 13 74 001 47 44 5.1 3. 0. 3. <0. .4 .9 1 9 68 57 01 In addition Table 5 shows highly significant improvement in symptoms also. Numbness is relieved by 70%, tingling is relieved by 72%, burning sensation is reduced by 77.5% whereas pain in lower limbs is relieved by 64% . Sensations Mean B.T Reported in no S.D A.T of patients In % Values S.E t p in percentage Numbness 2.11 0.63 27 0.7 Tingling 1.79 0.5 6.47 72 1.13 10.26 <0.001 Burning 1.93 0.33 16 0.82 77.59 0.2 7.35 <0.001 0.6 0.17 7.41 <0.001 14 70.18 0.13 10.99 <0.001 sensation Pain in lower 1.92 0.69 13 64 limb Table 5 : Improvement in symptoms Conclusion: the patients of diabetic neuropathy. Both of these drugs are also safe as did not produce It can be stated from the results that any adverse features. Ayurvedic drugs used in present study are effective to revert the diminished perception The study is continuous to get large number of sensations like vibration, cold and heat. of patients. There is highly significant reduction in other symptoms including numbness, tingling, burning sensation and pain in lower limbs in 60 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Acknowledgment: 2. Aacharya Vaidya Jadavaji Trikamji., editor. Varanasi: Chaukhamba Sanskrit Authors are thankful to the management and sansthan. 2nd the Principal YMT Ayurveic college for Varanasi: providing the permission and the facilities ed. 47. Vol. Chaukhamba 4. Sanskrit sansthan; 1990. Agnivesha, Charaka, for this study. Dridhabala. Charaka samhita, Nidana Sthana, Adhyaya. References: 3. Oza Nighantu/Candanadi 1. Davidson S. Davidson's Principles and Practice of Medicine.20th Jarkhande., Dr. Dhanvantari Varga. 2nd ed. Vol. 84, Varanasi: Chaukhambha ed. Surbharti Prakashana; 1996. Amsterdam: Churchil Livingstone Elsevier publication; 2006. p. 843. Cite this article: Effect of Praval Bhasma on Diabetic Neuropathy Komal S.Raut, B.D. Gharjare Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):55-61 61 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_10 ______________________________________________________________________________________________________________________________________________________ ROLE OF PANCHA TIKTA GHRUTA MATRA BASTI IN PROCTITIS. ___________________________________________________________________________ Moghal Hasan*1. Sanjeev Yadav2 ___________________________________________________________________________ 1. M.S (SCHOLAR) SHALYA TANTRA 2. Professor, SHALYA TANTRA Y.M.T. Ayurvedic medical college & PG Institute, Navi Mumbai. * Corresponding Author: [email protected] & +91-9819526877 ___________________________________________________________________________ which is tikta rasa Pradhana aushada is Abstract: helpful in pitta shamana and rakta shuddhi. Proctitis is inflammation of rectal mucosa When it is administered in the form of matra which can become a chronic condition if not basti it directly acts on the affected site of treated properly and affects the proximal colon later. Proctitis results in proctitis that is guda pradesha and helps to an provide relief in proctitis or guda paka. unrestrained inflammatory response, with the inflammatory cells being products that Key words: Proctitis, Gudapaka, Matra mediate cellular tissue injury at the level of basti, Panchatikta Ghrita rectal mucosa[1]. The treatment of proctitis Introduction: is generally conservative one. Guda paka is a condition mentioned in ayurveda which Inflammation of mucosa of rectum and anal can be correlated with proctitis. It is canal is termed as proctitis. Aetiology of mentioned as symptom of many pittaja and proctitis is unknown. The concept that the raktaja conditions like pittaja atisara, rakta condition is a mild and limited form of vruddhi etc. Guda paka is mainly because of ulcerative colitis (although actual ulceration rakta and pitta dushti. Pancha tikta ghruta is often not present) is the most acceptable 62 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ hypothesis.1 The symptoms are tenesmus in the classics. It is termed so, because the (Although the patient has a frequent intense dose of Sneha used in is very less as desire to defaecate but no faeces is passed or compared to the dose of Sneha Basti.[3] passed in very little amount), the passage of Regarding the qualities of Matra Basti it has blood and mucus along with stools and pain been said that, it is promotive of strength, at. Proctoscopy is seldom sufficient, and demand no strict regimen of diet causes sigmoidoscopy is the more valuable method easy elimination of feces, urine of examination.[1] On rectal examination, curative of Vata disorder. It can be the mucosa feels warm, smooth and tender. administered at all times, in all seasons and Often, there is some blood on the examining is harmless. [4] and finger. Proctoscopic and sigmoidoscopic Modern medicine has limited source of examination shows inflamed mucosa of the rectum, but usually no ulceration. [1] medical The diarrhoeal, cm from the anus, with the mucosa above Gudapaaka, which as temporary salazopyrine. these modern drugs have a huge list of possible side this level being normal. Proctitis can be to such medication with intestinal antibiotics, anti inflammation usually extends for only 5–15 correlateded treatment effects. Keeping all these facts in mind it is was decided to study the role of panchatikta mentioned in Ayurvedic texts in few ghrita matra basti in proctitis.. conditions like pittaja disorders and rakta vruddhi conditions. According to ayurveda Materials and Methods: Gudapaaka is mainly because of pitta and rakta vriddhi. panchatikta Materials: ghrita preparation • Panchtikta Ghrita which was prepared as contains patola, kantkari, vasa, guduchi and nimba as described in Sharangdhara Samhita. main ingridients. All these dravyasare of • 10 patients with the sign and symptoms of tikta rasa. It is indicated mainly in proctitis conditions like vishama jwara, pandu roga, from OPD/IPD of Y.M.T. Ayurvedic college and hospital kushta, visarpa, krumi and arshas as abhyantara yoga. [2] Matra Basti is a type of • Red rubber catheter, Dispovan syringe of Sneha Basti i.e. Anuvasana Basti described 20 ml, Cotton pads and Surgical gloves. 63 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ of defecation, ano rectal pain, tenderness, Methods: local raise in temperature and erythema in Inclusion criteria: ano rectal mucosa. 1. Patients having signs and symptoms The above observation is recorded on 1st, of proctitis were taken under this 7th, 14th and 21st day visit of the patient. A study. special 2. Patients between 18-60 years of age proforma was prepared for collection of data on successive follow ups. and from both the sex were selected. Observations and results: Exclusion criteria: Grades of clinical signs and symptoms 1. Age below 18 and above 60 years observed in 10 patients of study on 1st visit from both sexes. and each follow- up. 2. Cases of proctitis which developed During the whole study period it has been observed all clinical due to STD/Radiation exposure and signs and symptoms started decreasing associated with ulcerative colitis and gradually on each follow-up. After the last crohns disease. follow-up there was a significant decrease in 3. Acute abdominal pain all clinical signs and symptoms. There was 4. Stool frequency more than 10 per 88.89% of relief in tenesmus, 87.50% relief day. was observed in mucous discharge in stools. 94.12% relief was observed in Criteria for assessment: bleeding per rectum, 93.75% relief was The treatment effect has been assessed on seen in increased frequency of defecation. the basis of the relief in signs and symptoms Ano rectal pain during and after defecation of the disease. This was done on every was relieved by 89.48%, tenderness on per follow up day at OPD level and proctoscopy rectal digital examination was reduced by was performed on every follow up day. 94.45%. There was 88.89% of relief in Scoring pattern 0 to 3 grades was adopted raised local temperature and 90% relief to determine the relief in the cardinal signs was observed in erythema of ano rectal and mucosa. symptoms- tenesmus, mucous discharge, bleeding per rectum, frequency 64 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ No of patients Grades Grade 3 Grade 2 Grade 1 Grade 0 Mucous tenesmus discharge Bleeding Frequency per of rectum defecation Ano rectal pain tenderness BT AT BT AT BT AT BT AT BT AT BT AT 1 0 0 0 0 0 0 0 2 0 1 0 6 0 6 0 7 0 6 0 5 0 6 0 3 2 4 2 3 1 4 1 3 2 3 1 0 8 0 8 0 9 0 9 0 8 0 9 sushruta in context of vrana shopha No of patients Erythema Present/ Raised local Absent temperature ano of mentioned that, without pitta dosha paaka rectal can ’t occur at any site of body6 ( naa mucosa paakah pittadrute). There is predominance of pitta dosha in this condition along with association of vata (apana vata), kapha and BT AT BT AT Present 9 1 10 1 rakta also, as it is obvious by looking at sign Absent 1 9 0 9 and symptoms observed in proctitis. Panchatikta ghruta is tikta rasa Pradhana, it Discussion: is sheeta in veerya thus helps in pitta Proctitis is nothing but the inflammation of shamana. The drug is in the form of ghrita anal and and is given in the form of basti so it is rectal mucosa which can be considered as gudapaaka mentioned in helpful in vata shamana. When panchatikta word in this ghrita is given as matra basti it directly acts Ayurvedic texts. Paaka context correlated can be to acute on the affected site of guda. It inflammatory process occurring at the relieve pitta vruddhi related mucosa of rectum and anus. symptoms Acharya 65 helps to sign and in proctitis like; raised local ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ mucosa, 4. This study is a small scale trial tenderness and bleeding per rectum and including only 10 patients. To get vata dushti related symptoms like tenesmus, more specific results study should be increased frequency of defecation and pain carried out on large sample size. temperature, erythema at ano-rectal region. of Matra Basti can be References: given regularly, demand s no strict regimen 1. Bailey And Love’s Short Practice Of Surgery, 25th edition, chapter 68, page no 1226, 2. Sharangdhara Samhita with Jivanprada Hindi Commentary, Dr.Shailaja Srivastava, Madhyamkhand, Chpater 9, Page 215, Chaukhambha Orientalia, 2005. 3. Agnivesh,” Charak Samhita”, with , can be administered at all times, in all seasons and is harmless. so that the patient can treat the ailment without hindering his routine life. Thus all constituents of formulation effectively work on shamana of the doshas involved in gudapaka or proctitis. Vaidyamanorama Hindi Commentary by Acharya Vidhyadhar Shukla and Prof. Ravi Dutt Tripathi, Siddhisthan, Chapter 4, Verse no.52-54, Chaukhambha Sanskrit Pratishthan, 2007. 4. SUSRUTA SAMHITA: sutrasthanam Sanskrit text with ayurvedarahasyadipika Hindi commentary by Dr.Bhaskar Govind Ghanekar chapter 17, verse no. 7, Published by Meharchand Lachmandas Publications, New Delhi. Conclusion: 1. After analyzing the data and the observations, we have come to conclusion that ‘Panchtikta Ghrita Matra Basti in morning for 21 days’ is found to be effective in proctitis. 2. The formulation did not have any adverse effect or toxic effect or any side effect and was found to be significantly effective in proctitis. 3. The formulation is easily available and is cost effective. Cite this article: ROLE OF PANCHA TIKTA GHRUTA MATRA BASTI IN PROCTITIS. Moghal Hasan, Sanjeev Yadav Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):62-66 66 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_11 ______________________________________________________________________________________________________________________________________________________ A COMPARATIVE STUDY OF MEDOSARA AND MEDOVRIDDHI WITH RESPECT TO SERUM CHOLESTEROL __________________________________________________________________________ Jaykumar Sadashiv Ade* 1 __________________________________________________________________________ 1. Assistant Professor, Kriya Sharir Department, SGR Ayurved College & Hospital, Solapur. *Corresponding Author: Email id: [email protected] Mobile No +919822369266 __________________________________________________________________________ ABSTRACT: in HDL & LDL level. Conclusion of study is that by analyzing lipid profile and The present study was conducted in estimating two groups. One of them was Medosara & identification another was Medovriddhi. 30 Medosara Medosarata people were selected by survey method while 30 Medovriddhi patients serum cholesterol of can level, Medovriddhi be confirmed and to a significant extent. were selected from OPD. In both groups lipid KEYWORD: Medosara, profile was carried out from fasting venous Serum cholesterol. Medovriddhi, blood sample. The observations were made INTRODUCTION: to see the level of serum cholesterol & other components of lipid in Medosarata & Medovriddhi. carried out Human body as well as the psyche Comparative study was between Medosarata both can get affected by various diseases. & The homeostasis, which is termed as Medovriddhi with special reference to lipid ‘doshasamyam’ in Ayurveda, stands for profile. The result suggest that “t” value was harmonious balance of dynamism and that nonsignificant in TG level where as it is of body humors- vata, pitta and kapha. significant for TC level & highly significant These humors termed as dosha regulates 67 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ every system even in a state of imbalance to derangement in its function. These must and attempts to restore the physiology. not at all be confused with the increase in its According is normal structure or functioning, either by considered as principal factor governing vriddhi (increase in bulk and mass) or these activities. [1] prakop (hyper dynamic state). Vriddhi and Sushruta Vata dosha kshaya are considered abnormal conditions The dhatu are the substances which and differ from sarata. If Medodhatu in provide support to the body and helps to body becomes victim to this vriddhi, the sustain the body, by providing strength and resultant condition is called as Medovriddhi, making themselves available for the purpose of derivation of energy. which also contributes to the development These structural of disease known as sthaulya. arrangements and their functional activities This sthaulya, described almost in all major texts should be in a physiological limit. Anything, of Ayurveda is similar to Obesity. less or more and low or high, will lead to the state of pathology. The increase or Almost everywhere in the world, last decrease in bulk of any dhatu or in dynamic centuries developments have lead activity of any dosha governing and significant alterations in life style. On the regulating its metabolism will invite illness. top of these are increased caloric and fat One more factor known as ‘agni’ plays a intake and reduction in physical activities. pivotal role in this. This leads to the agnimandya and results in reduced utilization of energy providing Dhatus have same set of functions in sources. The meda major source of energy, every individual but quality and ‘richness’ mostly in body in absence of other available of this function may vary from person to source of energy. If it is underutilized, or is person. This is decided by prakriti of a accumulated in excess, then it will start person and more by a ‘sarata’ of that increasing and eventually will lead to particular dhatu. vriddhi. This manifests into metabolic syndrome related diseases. The result can be This sarata is beneficial in two explicitly seen in the form of diseases like ways. The person enjoys the functional diabetes, benefits of activity of that particular dhatu hyperlipidaemia, hypertension, obesity and many more. Hyperlipidaemia and there are rare chances that he will suffer 68 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ alone curretly affects more than 10% of the Hina & madhyam sarata of global population and India is no exception Medodhatu person were excluded. to this. Obesity is said to lead to 30,000 2) Medovriddhi premature deaths each year and it is a) Patients of medovriddhi were excluded those having any endocrinal abnormality which is or appear to be causative factor for obesity b) Congestive Cardiac Failure. c) Nephrotic Syndrome d) Acute or Chronic Renal Failure e) Major Depression f) Diabetes Mellitus g) Familial or hereditary dyslipidemia and/or hypercholesteremia h) Those who were on steroid therapy for any reason. shortening the lives of people by an average of nine years. AIM & OBJECTIVES To ascertain parameters for analyzing the absence or presence of medovriddhi and medosarta. To establish relationship between the finding of different units in lipid profile and presence of medovriddhi and medosarata. METHOD & MATERIALS Plan of study Selection of cases It was randomized, comparative study. Ethics committee’s approval was taken. Span period required for this study was from2007 to 2009. 30 clinically diagnosed individuals of Medovriddhi were selected from OPD of Dept. of Rognidan & Vikrutividyan, Shri Ayurved College, Nagpur. 30 individual of Medosara were also selected by survey method. The investigations done in past if any evaluated and fasting venous blood sample was drawn to get the lipid profile. Lipid profile was done in all patient of medovriddhi and medosara person. Inclusion criteria 1) 30 individuals each of Medosara & Medovriddhi. 2) Both male & female 3) Age between 20& 30 years. 4) Only uttam sarata of Medodhatu individuals Exclusion Criteria PARAMETERS FOR COMPARATIVE STUDY OF MEDOSARA AND MEDOVRIDDHI 1) Medosara 69 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 1) Serum cholesterol Parameter Medosara Medovriddhi X 122.56 108.54 S.D. 36.87 35.53 S.E. 6.73 6.48 2) Triglycerides 3) HDL 4) LDL OBSERVATION t = 1.4996 P > 0.05 Statistical analysis Table above shows that there is no difference between in the levels of T.G. in both study groups. For comparison unpaired “t” test was applied. 1) Comparison of Medosara and Medovriddhi group with respect to T.G. T.G. Medosara Medovriddhi 2) Comparison between Medosara and Medovriddhi with respect to T.C. T.C. (in mg/dl) Upto 180 180 – 220 220 – 280 > 280 Total Total (in mg/dl) 40 - 25 160 (83.33%) 160 – 220 220 – 05 29 (96.66%) 54 00 05 (16.67%) 00 01 (3.34%) 01 > 280 00 00 00 Total 30 30 60 280 Medosara Medovriddhi Total 27 (90%) 20 (66.67%) 47 03 (10%) 09 (30.00%) 12 00 00 00 00 30 01 (03.34%) 30 01 60 As far as, quantitative analysis is concerned, 90% Medosara subjects were having total cholesterol below 180 mg/dl. Very few of them were found to have total cholesterol more than 180 mg/dl. There was not a single subject who has total cholesterol above 220 mg/dl. In Medovriddhi group, almost two third patients recorded this level upto 180 mg/dl. One third have gone over 180 mg/dl. One patient showed the level crossing 280 mg/dl. The table above shows that high incidence of TG (40 – 160 mg/dl) in both condition i.e. (83.33%) in Medosara and 96.66% in Medovriddhi.) 70 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ t = 8.6305 Table above shows that high incidence of total cholesterol in (upto 180) level i.e. 90% in Medosara and 66.67% in Medovriddhi. Parameter X S.D. S.E. Medosara As P is < 0.001; it is highly significant. This shows that there is difference between Medosara and Medovriddhi with respect to HDL. Medovriddhi 150.11 16.41 2.99 P < 0.001 4) Comparison between Medosara and Medovriddhi with respect to LDL. 171.65 32.09 5.85 t = 3.2722 , P < 0.05 As P is less than 0.05, it is significant. Therefore there is difference between Medosara and Medovriddhi with respect to total cholesterol. 3) Comparison between Medosara and Medovriddhi with respect to HDL. LDL Upto > 60 70 – 100 100 – 130 > 130 Medosara 22 (73.34%) 07 (23.33%) 01 (03.33%) 00 Medovriddhi 01 (03.33%) Total 23 01 (03.33%) 23 16 (53.34%) 17 06 (20%) 06 Total 30 30 60 Table above shows that high incidence of HDL > 60 45 – 60 30 – 45 < 30 Total Medosara 22 (73.32%) 04 (13.34%) 04 (13.34%) 00 30 Medovriddhi 00 Total 22 LDL was found in Medosara in first grade 09 (10%) 13 Medovriddhi it was found in ‘III’; (i.e. in i.e. upto 70 mg/dl (73.34%) and that in 100 – 130 mg/dl, i.e. 53.34%). 21 (90%) 25 00 30 00 60 Parameter X Table above shows that, high incidence was found in Medosara in grade I (> 60 mg/dl) i.e. 73.32% while in Medovriddhi it was found in grade III (30 – 45 mg/dl) i.e. 90%. Parameter X S.D. S.E. Medosara 63.43 12.46 1.23 Medosara 62.07 Medovriddhi 109.12 S.D. 19.06 26.77 S.E. 3.48 4.88 t = 7.804, P < 0.001 As P value is less than 0.001. It is Medovriddhi 41.04 6.77 6.77 highly significant. So there is difference 71 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ between Medosara and Medovriddhi with The conditions which have ‘one dhatu respect to LDL. common as their root’. The clinical scenario of medovriddhi DISCUSSION and obesity in modern Medicine and Sarata and vriddhi, these two ayurvedic text is almost same. However, the concepts are unique to ayurveda. Though medosarata in ayurveda cannot be seen the terms like ‘increase and hypertrophy’ anywhere in modern Medicine. It was can be used for vriddhi and ‘excellency of considered that some parameters may be the dhatu’ can be used for the sarata. These found common to both for medovriddhi and terms hardly illuminate the true meanings of obesity. The parameter representing meda in sarata and vriddhi. Only those who have body can also be analyzed to see whether it studied ayurveda and have learnt its has some relation with medosarata also; so philosophy can understand this and at the that we can distinguish medovriddhi from same time they may not be able to express it medosarata, by using this parameter. For and to make it simple for the person who this purpose, total cholesterol was selected. has studied other streams of Medicine, This especially modern Medicine. and growing molecules popularity differentiation of medovriddhi on synthesing under-utilization of energy leading to medovriddhi. Therefore there is scope to put efforts have been made in this present study parameter keep this is the same manner describing the exception to this. The sincere and honest such will cause problems to health. Ayurveda explains we study. Dosha, dhatu and mala are no one from excess quantity in body. The same may provide modern parameters for everything find synthesized cholesterol which will get accumulated in of ayurveda globally, the need is felt to to is multiple molecules of acetyl co-A. These In today’s era of evidence based Medicine cholesterol these two things in the same compartment. for and Cholesterol in body is distributed in medosarata and to guess whether it has variety of lipoproteins. The majority is in some co-relation with the presence or the absence of these two different conditions. form of low density lipoprotein moderately in the form of IDL, less in VLDL and much smaller in HDL. 72 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ The effort was made to see the relative values of these The concepts of sarata and vriddhi components are well studied by Acharyas in belonging to the family of cholesterol, both detail. The features are categorically in medovriddhi and medosarata. explained; especially for saratva, which can be divided into physical, It was observed that: physiological and psycho-spiritual features. [2] In both condition incidence of male is more than female. Medovriddhi is more observed in higher economical class. As far as dietary habits are concerned vegetarian were found more in Medosarata and nonvegetarian were more in Medovriddhi. Medovriddhi was observed in persons with sedentary life style while Medosarata was observed more in physically active individuals. ‘t’ value is non-significant in triglycerides level of lipid profile i.e. t = 1.4996 and P> 0.05. t value is significant for total cholesterol level (t = 3.722 and P < 0.01.) ‘t’ value is highly significant in HDL level. (t = 8.6305 and P < 0.001.) ‘t’ value of LDL is also highly significant (t = 7.8401 and P < 0.001.) Dhatu Vriddhi causes increase in the bulk of tissues and at the same time decreasing the functional capacity of that particular dhatu. At the same time, it may jeopardize the nourishment and growth of further dhatu. The agni plays pivotal role in metabolism of all dhatus in body. This stimulates machinery the which metabolic consumes substrate.The majority of these are provided by medodhatu after rasa dhatu. Meda usually is in a relatively solid state in circulating. body This but has still keep Parthivata which can be turned into a Jaliyatva as and when required. The same is found when triglycerides stored in CONCLUSION adipose tissue are split in fatty acids Conceptual Study: and glycerol. [3] Experimental Study: 73 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 30 subjects were selected for each phospholipids from tissue and organs group, and back to liver for degradation and medosarata. The target age group elimination. It prevents the deposition was from 20 years to 30 years. of cholesterol on the walls of arteries While analyzing the symptoms in by carrying cholesterol away from medosara group, it was observed arteries to liver. High level of HDL is that these people have almost all good indicator of healthy heart cardinal features of full grown and because physiologically strong medodhatu. cholesterol level. [5] Medosara people This is likely due to Purnatva of have shown statistically rising HDL dhatu-nirmiti. which is popularly known as good Medovriddhi people showed more cholesterol. i.e. medovriddhi prominence in terms of structural Low it reduces density the blood lipoproteins: considered alterations in terms of functional because it carrier cholesterol and impact. This is probably due to phospholipids from liver to different tarunavashta. The symptoms worsen areas of body viz. muscle, other tissue with the advancing age. and organ such as heart. It is my sample majority responsible of “Bad is variations and had shown fewer In as It for cholesterol” deposition of medovriddhi subjects were form cholesterol on wall of arteries causing higher socio-economic classes. This atherosclerosis. High level of LDL suggests that there is strong link increases the risk of heart disease. between the causative factors (over Medovriddhi nutrition and sedentary life style) statistically significant rise in LDL, and medovriddhi (obesity). [4] people have [6] shown which is popularly known as “bad There cholesterol”. was no such link found between the sarata and socio-economic status in Clinical Study: sample studied. HDL – High density lipoprotein is Abnormal accumulation of meda referred as the “Good Cholesterol” dhatu because it carries cholesterol and medodushti. Medovriddhi, if not 74 in body is known as ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ treated, advances to and invites the diseases by 1. Sushruta Samhita of maharsi causing Susruta edited with Ayurved needs Tattva Sandipika Part I by the Kaviraj Dr. Ambikdatta Shastri substances reach to every cell and Nidan sthana Chapter 1 verse strotorodha.Vyan enough space tissue of body. Vayu for [7] helping The accumulation No no 229 , Chaukhamba Sanskrit Sansthan, nourishment of further dhatus like Varanashi, reprint 2007. 2. Agnivesh charaksamhita these people are prone to develop elaborated coronary artery disease (because of Dradhabala atherosclerosis), hypertension (due Cahndrika Hindi Commentory to increased peripheral resistance), Part I Dr Brahamanand Tripathi diabetes, neuropathy, osteoporosis & Dr Ganga Sahay Pandey and impotence. [8] Viman Sthana Chapter 8 Verse No ACKNOWLEDGEMENT by 103-110 Charaka with page Chaukhamba & Charak 763-766 Surbharti Prakashan Varanasi 2006. I am very grateful to Dr Maneesha 3. Textbook of Physiology, Guyton Kothekar, HOD Dept of kriya Sharir & Hall, Unit no XII, chapter no Shri Ayurved college, Nagpur for 68, page no 682, Saunders An their support. My special thanks to Imprint Of Elsevier 2006. my Guide Dr. Snehavibha Pathak for 4. API their valuable guidance. page of meda in strotas hampers the asthi, majja and shukra. This is why 10, Textbook of Medicine, Editor in chief Shantilal Shah , I take this opportunity to thank Dr Section IX, Chapter 8, page 442, Raviraj Pardeshi & Dr Santosh Published by Association of Chavan who helped me at every physician Of India, Bombay stage for preparation of thesis. ,1988. 5. Essential of Medicial Physiology REFERENCES: , K Sembulingam & Prema Sembulingam, Section 4, chapter 75 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 47, page 295, JAYPEE Brothers Srikantha Murthy, Sharir sthana Medical Publication, New Delhi, chapter 6 verse 28 page 84 2008. Published 6. Essential of Medicial Physiology by Chaukhambha orientalia, Third Edition 2001. , K Sembulingam & Prema 8. API Textbook of Medicine, Sembulingam, Section 4, chapter Editor in chief Shantilal Shah , 47, page 295, JAYPEE Brothers Section VII, Chapter 14, page Medical Publication, New Delhi, 266, Published by Association of 2008. physician Of India, Bombay, 7. Astanga Samgraha of Vagbhata, 1988. part II, Translated by Prof. K.R. Cite this article: A COMPARATIVE STUDY OF MEDOSARA AND MEDOVRIDDHI WITH RESPECT TO SERUM CHOLESTEROL Jaykumar Sadashiv Ade Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):67-76 76 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_12 ______________________________________________________________________________________________________________________________________________________ Ayurved management in LUMBAR CANAL STENOSIS: A case study ___________________________________________________________________________ Naik Minal S.*1, Meenakshi Rewadkar-Kole2 ___________________________________________________________________________ 1. PG scholar (Kayachikitsa) 2. Assistant Professor, kayachikitsa Dept., Email ID: [email protected] R.A.Podar medical college, Worli * Corresponding Author: Email ID: [email protected]; Mobile no.9821266343 ___________________________________________________________________________ temporarily. Hence she came in Podar ABSTRACT: hospital for ayurvedic management. She Aim: Lumbar canal stenosis is a structural was further advised MRI lumbar spine deformity. Modern medicine has surgical which showed intervertebral disc protrusion treatment for this disorder. A case reported at multiple levels and lumbar canal stenosis. here is treated with ayurvedic treatment. She was initially given sathanika and sarvadehika pachana chikitsa i.e. sinhanad Method: A female patient of 61 year old, guggula, rasnasaptaka kwatha, pachan farmer by occupation came with complaints yogabasti krama, sahachara taila katibasti, of severe low backache, radiating pain in sthanika snehana swedana for initial 7 days. right hip to foot, tingling, and intermittent After this she was given asthibalya and claudication. These symptoms were present majjapurana chikitsa i.e. lakshadi guggula, since one year but got aggravated since 15 Baladi kshirapaka, panchatiktaghritkshira days. Patient consulted at orthopedician. He basti for 30 days. Along with this treatment advised x ray lumbar spine. It showed lumber belt, bed rest (initially) and later on degenerative changes in lumbosacral spine. leg exercises were also advised. He gave her pain relieving treatment and calcium supplement which worked 77 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Result: After 7 days of pachana karma Lumbar canal stenosis. The studies patient started feeling better. She got almost regarding this topic are very few. Among 90% reliefs after one month. them a clinical study of Nirgundi Ghana Vati and Matra Basti in the management of KEY WORDS: Lumber canal stenosis, Gridhrasi with special reference to sciatica Katibasti, Panchatiktaghritakshira basti. had been done in Gujarat Ayurveda University, Jamnagar.[1] INTRODUCTION: Case history: Lumbar canal stenosis is term used to describe developmental or congenital A female patient of 61 years old, narrowing of spinal canal that produces farmer compression of neural elements before their numbness over right leg, and intermittent age & elderly. Diagnosis is essentially claudication since 1 year and it was clinical & only supported by radiological increased since 15 days. She has taken investigation. allopathic treatment, but not relieved completely. Hence she came in our hospital Pathophysiology is related to cord for ayurvedic treatment. She was admitted dysfunction elicited by a combination of for further investigations and treatment. She mechanical compression & degenerative was admitted on 15th July 2013 and was instability. With ageing, inter vertebral disc discharged on 10th August 2013. degenerates & collapses leading to spur limitations in from right hip to foot, tingling, and most frequently causing morbidity in middle are presented complaints of low backache, radiating pain stenosis is progressive disorder of spine There occupation Kayachikitsa outpatient department with exit from neural foramen. Lumbar canal formation. by in History of past illness: Not a K/C/O HTN treatment; surgeries have failure in old age /DM/BA/PTB any other medical illness patients and other complications. No H/O major operative/BT/ Drug allergy Here is a case of Lumbar canal stenosis, which was treated with ayurvedic Samanya Parikshana: therapy & got relief. Hence, Ayurveda can Mala : Malavashtambha have non-invasive, long lasting remedy for 78 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Sparsha : Avishesha Other strotas were normal. Jivha : Sama INVESTIGATIONS: Akriti : Madhyama X-ray Lumbosacral spine (16/7/2013): Marginal osteophytes at L2 &L3, Space Prakriti : Vatapradhana Kaphanubandhi reduction between L3-L4 & L4-L5. Other findings were normal. MRI LUMBOSACRAL SPINE (18/7/2013): Strotas Parikshana: L2-L3disc reveals mild posterior bulge Mansavaha : Deep Tendon Reflexes : indenting thecal sac neural without neural Ankle and knee reflexes of right leg were compression. brisk. Marginal osteophytes at multiple levels. Leg Ankle Knee Biceps Tricep Rt + + ++ ++ L3-L4 poster central protrusion indenting thecal sac without neural compression. Mild leg Lt + ++ ++ facetal ++ arthropathy & ligamentum flavum thickening is noted. leg L4-L5 posterocentral protrusion compressing thecal sac & bilateral L5 nerve roots. Facetal arthropathy & ligament flavum thickening Majjavaha: Sandhi Parikshana at L5 contributing to Central Canal Stenosis. SLRT : (straight leg raising test): TREATMENT REVIEW: Right Leg- 60 Left Leg- 80 A) Chiktsa in Samavastha : It was given for Bilateral - Not possible 7 days. Forward bending: upto ankle – painful. 1) Poorvakarma: snehan nadi swedan at back to both feet. Local tenderness: L3-L4-L5 79 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 2) Shodhana Karma: Pachan basti: 3) Local: Kaitbasti with Bala taila Decoction of dashmool, rasna, palashmool, erandamool-nirooha 350ml on Internal medications: empty stomach in the morning and sahachar taila 1) Lakshadi guggula 1 gm three times a day anuvasan 60ml after meal, for 7days. with warm water 3) Local: Kaitbasti with sahachar taila 2) Bala, ashwagandha,guduchi,shunthi kshirapaka 30ml two times a day. Internal medications: 3) Gandharva haritaki 3gm at bedtime with 1) Sinhanada guggula 1 gm warm water three times a day with warm water. OBSERVATION: 2) Rasnasaptaka kwath 30ml two times a Symptoms Before After day. treatment Katishool +++ Katigraha +++ Tingling at +++ hip to both feet 3) Gandhrva haritaki 3gm at bedtime with warm water. B) Chikitsa in niramavastha: It was given treatment + - for 30 days. S.L.R.Test : 1) Poorvakarma: snehan nadi swedan at Date 15/7/2 013 Rt leg 60% Lt leg 80% Both Not legs possibl e Forw Upto ard ankle bendi painful ng back to both feet. 2) Basti-Panchatikta ghritakshir basti 120ml. It was given after meal continuously for 7 days and dashmoola nirooha was given to subside some effects of kshirabasti such as abdominal heaviness, flatulence etc. Again 7 days cycle of kshirabasti was repeated. Total 3 cycles of 7 days kshirabasti were done. 80 23/7/2 013 80% 90% 30% 26/7/2 013 90% 90% 40% 10/8/2 013 90% 90% 80% upto ankle Upto Upto ankle,n toes, o pain not painful ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ of body. Hence might be helpful for DISCUSSION: relieving neural oedema. Patient had relief Hetu of Katigata vata in this patient in symptoms such as tingling, numbness. was aticheshta and vardhakya. Both vitiates vata. Vataprakopa leads to asthi and majja panchakarma pachana and shoolanashana. and specifically tikta ghrita kshira basti for After pachana chikitsa , patient had [2] asthivaha strotasa vikara . relief in above symptoms. But she had pain after Rest is the most important treatment majjapuranartha rest. She was advised to put lumbar belt guggula, while sitting, standing and walking position. Honey[4] provides phosphorous and calcium which are useful in bone metabolism. Saindhava is sukshma[5] in nature which restricted movements, morning stiffness). helps Hence she was given pachana basti, basti kshirapaka, Both of them also improve majja dhatu. (local tenderness at paraspinal region , Pachana baladi Lakshadi absorption & help in bone nourishment. had gurutva, constipation) and sthanika samata guggula. i.e. provide vitamin D which help in calcium sarvadehika samata (aroochi, sarvadehika and chikitsa improve asthi dhatvagni. Ghrita & milk divided in two stages i.e. samavastha and kwath walking, and also help in majjapurana. Panchatikta, In this case, the treatment was rasnasaptaka during are athisadhanakara, asthibalya in nature forward bending and sitting without support. patient i.e. panchatiktaghrita kshirabasti. These drugs She was told to avoid heavy exercise, Initially movements standing. She was given asthibalya and in this case. The patient was asked to take niramavastha. pachaka, Sinhanada guggula4 helps in deepana, on asthibalavardhana and majjapurana. advised is shothanashaka and vatahara in nature. dhatukshaya. Hence treatment was focused Charaka kwatha[3] Rasnasaptaka other ingredients microcellular sinhanada panchatiktaghritakshir contains to level. basti rich at Thus provides nutrition to asthi and majja dhatu. dashamoola,rasna,palashmaoola,erandamo ola, which are shoolahara, shothahara in Local treatment helped in pain relief. nature. Being hyperosmotic in nature it The patient was given snehan nadi swedan expels ama (toxins generated in body) out at back to both feet. Katibasti of sahachara 81 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 2. Agnivesha, ‘Charaka samhita’ with taila was done initially for 7 days and later on bala taila katibasti was done for 3 Ayurvedadipika weeks. In katibasti oil gets absorbed Chakrapanidatta edited by Vaidya through skin due to prolonged contact with Yadavaji Trikamaji skin. This might help in nourishment of Prologued by shleshaka kapha present at kasheruka Chaukhamba sandhi, nourishes ligaments, intervertebral Prakashana,Varanasi,Edition disc and also pacifies vata dosha. Hence it ,Pg.No.180 with CONCLUSION: Thus Lumbar canal these simple ayurvedic principles and kalpas , when administered both internally Acharya, Prof. R.H.Singh, of 2013 Chakrapanidatta Vaidyaprabha commentary stenosis can be treated in combination with by Surbharati 3. ‘Chakradatta’ helps in pain relief. Commentry by hindi Dr.Indradeva Tripathi, Chaukhamba Bhavan , Sanskrit Varanasi, Edition 2012.Pg.No.166-68 and externally. http://en.m.wikipedia.org/wiki/Hone y (Accessed on 2014 March 27) REFERENCES: 4. http://en.m.wikipedia.org/wiki/Hone y (Accessed on 2014 March 27) 1. Mumtaz Ali, M.D.,Ph.D., V. D. 5. ‘Sharangadhara Samhita’ containing Shukla, A. R. Dave, N. N. Bhatt, Gujarat Ayurved Anjananidana University, Jamnagar, Ayu journal 2010 Oct- Agnivesha Dec; 31(4): 456-460. Hindi of Maharshi annoted with DIPIKA Commentry by Bramhanand Tripathi. Pg.No.49. Cite this article: Ayurved management in LUMBAR CANAL STENOSIS: A case study Naik Minal S., Meenakshi Rewadkar-Kole Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):77-82 82 Dr. ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_13 ______________________________________________________________________________________________________________________________________________________ The Role Of Ayurvedic Medicine (I.E. Vanga Bhasma, Guduchi Satva & Pravalpishti) In The Management Of Dhatukshayajanya Sandhigatvat ________________________________________________________________________ Sanjay A. Pawade*1, Umesh N. Patil2 , R. J. Mundane3 ________________________________________________________________________ 1. Asst. Professor 09822933273 [email protected] 2. Associate Professor 09421312194 [email protected] 3. Professor & HOD 09850719571 [email protected] Deptt. Of Rognidan & Vikruti Vignyan, D. M. M. Ayurved College, Yavatmal. *Corresponding Author: [email protected] Mob. No. 09822933273 commonly found in elderly patients. This ABSTRACT- study was planned with an aim to evaluate Every person get older day by day. the role of ayurvedic medicine i.e. vanga Although the aging is inevitable bhasma, guduchi satva and pravalpishti in phenomenon and counted in swabhava bala in management of dhatukshayajanya pravritta vyadhies in Ayurveda.[1] sandhigatvat. Total 60 patients of Janusandhigatvat is one of them. dhatukshayajanya sandhigatvat were Janusandhigatvat is also known as selected. They were divided in two groups. osteoarthritis. It is not a life threatening Group A and Group B. Group A patients disease, but it happens at a wrong end of were treated with vatshamak Yog along with life. It is most prevalent and the leading Balya Yog (i.e. vanga bhasma, guduchi cause of disability in India affects over 15 satva and pravalpishti) and group B patients million Indians each year.[2] In Ayurved, were treated only with vatshamak Yog. The Samprapti of sandhigatvat is described as observations were recorded in prepared pro- dhatukshayajanya and strotorodhajanya.[3] forma and follow up was done after 2weeks, Dhatukshayajanya sandhigatvat is 4weeks and 6weeks. By applying chisqure 83 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ test and t test available data was statistically arthritis, a clinical syndrome in which low- analyzed. Finally balya yog is found to be grade inflammation of joints is caused by very useful in sandhigatvat. abnormal wearing of the cartilage that covers and act as a cushion inside the joints. KEY WORDS - Dhatukshayajanya, The decreased movement because of joint Sndhigatvat, Balya Yog, Vatshamak Yog, pain, regional muscles of joint may change Osteoarthritis, Aging. to atrophy and ligament may become more lax. Further O.A. is an articular abnormality INTRODUCTION – of synovial joints usually accompanied by Pain is an unfavorable sensation which sub-chondral sclerosis, bony cyst, joints brings an individual to the physician space narrowing and bony overgrowth at particularly is more painful when mobile joints. joints like Janusandhi (knee joint) of the Osteoarthritis of knee joint is seen most body is involved. The disease Sandhigata common in clinical practice of geriatric. Vata is more prone to be affected the knee Worldwide O.A. is the most common joint because it is most frequently involved articular disease of people of 65 years and joint in daily routine work as well weight above. The patients of O.A. need to take bearing joint. In pathogenesis of Sandhigata analgesics for daily and lifelong. [5] Vata it is found dominance of Vata Dosha. Janusandhigatvat is also known as Osteoarthritis (Sandhigatvat) is the leading osteoarthritis. degenerative knee disease leading to the “Osteoarthritis” is derived from the Greek need for knee replacement surgery. [4] The word ‘osteo’ means of the bone ‘arthro’ reasons behind sandhigatvat may be means ‘joint’ and ‘itis’ means inflammation growing obesity, sedentary lifestyle, dependence on unhealthy and junk food and of the joints. Hence an inflammatory change lack of exercise. In Ayurveda early aging is in the joints of bone is called as due to following five etiological factors as osteoarthritis. There are two types of O.A. mentioned in Madhav nidan such as [6] i.e. Primary O.A. (no underlying cause) and secondary O.A. (having underlying causes). Osteoarthritis is also known as degenerative 84 Pantha – Excessive walking ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Shita – Excessive intake of cold Acharya Madhava nidan has and cold potency dravyas described the lakshanas of aging vividly in Kadanna – Excessive intake of the following manner viz[7] jivaniya gunarahita ahara 1. Decreasing the body tissue, Vriddhaang satat sangam – sense organs, strength, vigor Sexual contacts with elder and vitality and enthusiasm female (Sahashinata, Dukha – in incompatible deeds Dhairya pranash) against will or mind 2. Effected with wrinkles, graying of hair and baldness Although it may not be possible to (Vali, Palita, Khalitya) prevent arthritis, one can reduce the risk of 3. Afflicted with complications developing the disease by maintaining like cough, dyspnoea etc. healthy weight (Excess weight put strain on 4. Incapable to perform all joints) by exercising regularly and by maintaining a good posture to protect the activities muscle and joints. gamanam) (Dandashrayen AIMS & OBJECTIVES:- In O.A. surgical therapy like knee joint replacement is very costly and after surgery patient has to continue analgesics To study the effect of trial drugs in for long duration. These analgesics and geriatric disorder with special reference steroids in old age may produce adverse to Janusandhigatvat. effects like gastritis, hyperacidity and some To find out less expensive, effective and time renal failure. Hence this study was easy treatment for complete cure of carried out to evaluate the efficacy of Balya Janusandhigatvat. Yog (i.e. vanga bhasma, guduchi satva and To study the Nidan panchak of Janusandhigatvat. pravalpishti) in the management of O.A. Signs and symptoms of Aging:- To validate old principal with practical oriented data. Clinical trials on various patients, statistical variation, Discussion, 85 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Conclusion to standardize and establish 1. Most Severe ++++ new facts and concepts in the 2. Severe management of Janusandhigatvat 3. Moderate ++ (Osteoarthritis) by Ayurved Therapy. 4. Mild + 5. No Symptom 0 +++ MATERIAL & METHODS:EXCLUSIVE CRITERIA:Selection of patients: Patients suffering from TB Randomly selected patients above Joints. DM, leprosy, the age of 40 years of Janusandhigatvat Malignancy of joints., AIDS, (Osteoarthritis) divided into two groups. severe anemia are excluded The final diagnosis was reached on the basis from this study. of signs and symptoms. TREATMENT DRUG:1. GROUP-A: - This group was treated with Vanga bhasma, Guduchi Satva and Vatshamak Yog– Praval Pishti along with Vatshamak Yog. 2. GROUP-B: - This group was treated Maharasnadi Kwath 20ml B.D. Yograj Guggulu 250mg B.D. Praval Panchamrut 250mg B.D. only with Vatshamak Yog. Symptoms:-[8] Balya Yog Sandhishul (Pain) Sandhishoth (Degenerative Guduchi Satva 250mg BD Vang Bhasma 125mg BD Praval Pishti 125mg BD Swelling/ Bony hard swelling) Sandhistabdhata (Locking Of joints) Vatpurnadruti Sparsh (Local Anupan – Goghrit. Crepitations) The symptoms are divided in four groups according to severity. 86 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Kidney function test is carried out of 2) Occupation Wise every patient (under study) before and after Distribution:- treatment Sr. OBSERVATIONS:- Occupation Group Group “A” “B” No. Result were observed and noted accordingly to clinical improvement in signs & symptoms on every follow up visit. Patients from both group followed up after 2 Weeks, 4 Weeks, and 6 Weeks. 1 Labor 4(13.33%) 3(10%) 2 Farmers 2(6.66%) 3(10%) 3 Businessing 3(10%) 4(13.33%) 4 Housewife 18(60%) 15(50%) 5 Servicemen 3(10%) 5(16.66%) 3) Disease Period Distribution CRITERIA FOR ASSESSMENT: - (Chronicity):- 1) Excellent Relief: - Complete Cure in Sr. Symptom and Signs. Years No. 2) Moderate Relief: - More Than 75 % Cure In Symptoms & Signs. 3) Mild Relief: - More Than 50% Cure In Symptoms & Sings. 4) No Relief: - No Changes in Symptoms & Sings. Group Group “A” “B” 6(20%) 1 0-1 5(16.66%) 2 2-3 7(23.33%) 8(26.66%) 3 4-5 9(30%) 7(23.33%) 4 6-10 5(16.66%) 6(20%) 5 11-15 2(6.66%) 1(3.33%) 6 16-20 2(6.66%) 2(6.66%) RESULT & DISCUSSION: 4) Prakrutiwise Distribution 1) Sex wise Distribution Sr. SR.NO Prakruti 1 Vatakaphaj 8(26.66%) 7(23.33%) 2 Vatapittaj 4(13.33%) 5(16.66%) 8(26.66%) 3 Pittavataj Female 24(80%) 22(73.33%) 4 Pittakaphaj 5 Kaphavataj 9(30%) 8(26.66%) 6 Kapahapittaj 2(6.66%) 3(10%) Sex 2 Group “B” “A” No 1 Group Male 6(20%) 87 Group-A 3(10%) Group-B 3(10%) 4(13.33%) 4(13.33%) ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ - (5)Agni wise distribution In this study vatakapha & kaphavata prakruti patients are more. SR.NO TYPES OF GRPOUP- GROUP-B AGNI A 1 VISHAM 15(50%) 14(46.66%) 2 TIKSHNA 3(10%) 2(6.66%) 3 MANDA 12(40%) 14(46.66%) - In agni wise distribution mandgani & vishamagni patients are more. - In group-A 70% patients showed Excellent relief and in group “B” 10% patients showed Excellent relief in signs and symptom. CURE RATE & DISEASE STATUS Classification of Results Sr. No. Group Excellent In group “A” 16.66% patients got Moderate relief in group “B” 50% Moderate Relief Relief 1 A 21(70%) 5(16.66%) 2 B 03(10%) 15(50%) - patient got Moderate relief in signs Mild Relief No Relief and symptom. In group “A” 10% patient got mild 03(10%) 01(3.33%) relief & in group “B” 13.33% patient 04(13.33%) 08(26.66%) got mild relief in signs and symptom. By applying chiqure test and t test - available data statistically analyzed with In group “A” 3.33% patient showed symptoms wise relief before & after no relief and in group “B” 26.66% treatment with respect to Sandhishul, patient showed no relief in signs and Sandhishoth, Sandhistabdhata and symptom. - Vatpurnadruti Sparsh etc. In group “A” 100% patient showed relief and in group “B” 90% patient Discussion on statistical ground - showed - symptom In group “A” 100% patient showed relief and in group “B” 92% patient House wives are more sufferers of showed Janusandhigatvat. - in Sandhishul (Pain). Female patients are more (76.66%) in this study - relief relief in symptom Sandhishoth (Swelling). 04-05 year chronic patients are more - in this study. In group “A” 96% patient showed relief and in group “B” 86% patient 88 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ showed - relief in - symptom Patient having cervical, lumber Sandhistabdhata (Locking of joints). spondilosys and Sciatica along with In group “A” 100% patient showed Janusandhigatvat relief and in group “B” 86% patient results with Balya Yog along with showed Vatshamak Yog relief Vatpurnadruti in symptom Sparsh - (Local Crepitus). got excellent Patients who were unable to walk without support before treatment, they are able to walk without support After analyzing of data following facts easily. are revealed - highly effective treatment for severe In Group “A” 96.75% patients osteoarthritis as a substitute of Total showed relief after receiving Balya Yog Knee Replacement (TKR) along with Vatshamak Yog and in Group - “B” 88.25% patients showed relief after Conclusion:The Females are more affected than males. receiving only Vatshamak Yog - It can be recommended that it is Overweight patients found more affected. symptomatic relief by References: Vatshamak Yog and trial drugs is 1. Ayurvediya Rogvigynan evum excellence when compared with only vikruti vigynan Dr. Radhavallabh Vatshamak Yog. - Relapses in group ”B” are more Sati, reprint edition 2006, when compared with group ”A” Chaukhambha orientalia, Varanasi. 2. www.healthcare.financialexpress.co Newly diagnosed cases got fast and m (Accessed on dated 15/09/2013) best relief. - 3. Carak Samhita: Volume II, Dr. Patient having severe osteoarthritis and advised for total Bramhanand Tripathi, reprint edition knee 2004, Choukhambha Surbharati replacement (TKR) got excellent Prakashan, Varanasi., page no. 948, results with Balya Yog along with chapter no. 28/58. Vatshamak Yog 89 ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 4. www.en.wikipedia.org/wiki/Osteoart 7. Madhavanidanam, Part II, revised & hritis (Accessed on dated edited by Prof. Yadunandana 15/09/2013) Upadhyaya, Chaukhambha Sanskrit Sansthan, Varanasi. 23rd edition 5. Dudhamal TS, Gupta SK, Jethava N. Clinical efficacy of Agnikarma in 1994. Page no. 500 Jararog nidanam Sandhigata Vata w.s.r. to Shloka no. 02 – 09 Osteoarthritis of Knee Joint-A pilot 8. Carak Samhita: Volume II, Dr. study published in Ayurlog: National Bramhanand Tripathi, reprint edition Journal of Research in Ayurved 2004, Choukhambha Surbharati Science-2013; 1(3): 74-84 Prakashan, Varanasi., page no. 942, 6. Madhavanidanam, Part II, revised & chapter no. 28/37. edited by Prof. Yadunandana 9. Methods in Biostatistics: B. K. Upadhyaya, Chaukhambha Sanskrit Mahajan, 16th edition, Jaypee Sansthan, Varanasi. 23rd edition Brothers Medical Publishers (P) 1994. Page no. 500. Jararog nidanam Limited, Noida, 2004. Shloka no. 01 Cite this article: The Role Of Ayurvedic Medicine (I.E. Vanga Bhasma, Guduchi Satva & Pravalpishti) In The Management Of Dhatukshayajanya Sandhigatvat Sanjay A. Pawade, Umesh N. Patil, R. J. Mundane Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):83-90 90 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Article_14 AYURVEDIC MANAGEMENT OF MYOTONIC DYSTROPHY: A CASE REPORT ___________________________________________________________________________ Ketaki Jalinder Jadhav*1, Prerana P. Jawale. 2 ___________________________________________________________________________ 1. PG student Kayachikitsa, 2. Assistant Professor, Dept.of Kaychikitsa, R.A.Podar ayu college, Worli, Mumbai-18. * Corresponding Author: E-mail:[email protected]; Mob no. 9867833483 __________________________________________________________________________ symptoms done clinically.According to ABSTRACT: ayurvedicdosha-dushyavichar patient has Myotonic dystrophy is a genetic disorder. The clinical expression given of Arogyavardhinivati,Chitrak+ Pippali+ vidangsiddhagruta for deepan myotonic dystrophy varies widely and ,pachan involves many systems other than muscle and mansagnivardhan.Balaguduchyadikwatha also. Neck muscles including flexors and ,Ashwagandhapak,cap. distal limb muscles are involved early. Palsinormgiven orally which is balya for mansa and Weakness of wrist extensor , quadriceps stimulant muscles occurs. formajjadhatu. In panchakarmachikitsa,yogbasti with dashmulaniruha and tiltailanuvasan given In this report, a case of 42 years old for 8 days as shodhanchikitsa followed by female patient diagnosed as myotonic karmabasti of balaguduchyadiniruha and dystrophy has given ayurvedic treatment. balatailanuvasan Observation and assessment of signs and given for 30 days.Shirodhara with brahmi and tiltail has 91 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ given for 14 days. In bahyachikitsa , patient disease can not be correlate with any given sarvangsnehan and swedan for 8 days specific vyadhi mentioned in samhitas, followed by sarvangpindswed for 28 days. (anuktavyadhi)but according to dosha- dushya vichar we can treat mansadaurbalya, Result: Lakshnikupashaya has manskshayato improve day to day life of mentioned on the basis of changes in muscle patient. power gradation, deep tendon reflexes, Patient’s name: SRS walking ability, pain/cramps in both lower limb etc. All parameters show good Age: 42 years improvement in patient. Sex: Female In modern medicine there is no specific treatment given for this disease and Desh: Anupa progression of this disease is worst. So, aim of this case report to show importance of ayurvedicmanagement, which can Occupation: House wife be Religion: Hindu helpful for thistype of patient to live their life better. KEY Chief complaints: WORDS: Myotonic dystrophy, 1. Katipradeshishool… since 2 1/2 yrs pachan, Balaguduchyadibasti, Pindswed 2. Ubhayahastapadadaurbalya … INTRODUCTION: since 1 1/2 yrs Myotonic dystrophy is a disorder in 3. Unabletowalk… since 11/2 yrs which usually proximal muscle remain stronger throuout coarse, but signs and 4. Pain and cramps in both calf muscles… symptoms involve gradual muscle weakness since 1 yrs and atrophy. It can lead to cardiac disturbances Gradually including patient heart may 5. Nidralpata(on & off) blocks. experience … since 1 yrs The patient was apparently alright respiratory insuffiency due to muscle of before 21/2 years, and then she had breathing get weaken. In Ayurveda this 92 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ complained of backache frequently. Then Mala: samyak she had an episode of epilepsy. She was a Weight:76kg known case of epilepsy, but not on regular treatment. Gradually she experienced Prakruti: kaphapradhanvatanubandhi weakness in both upper and lower limbs and decrease grip to catch anything. Patient BP: 110/80mm of Hg brought to KEM hospital for further work Mutra: samyak up. Patient has adviced EMG, NCS, MRIbrain ,MRI-LS Spine, 2D-echo. She Koshtha: Madhyam diagnosed as primary muscle disorder (mytonic dystrophy)in 2012. Patient was on anticonvulsant , pain killer Jivha: Alpasaam and StrotasParikshana: multivitamins, but does not improved. So,patient brought to Podar hospital for 1) Pranvaha: RS: AEBE ,NAD ayurvedic treatment. 2) Udakavaha – Trishna Family history: NAD 3) Annavaha: Aruchi4) No/H/O- DM /HTN/ PTB/ BA, Rasavaha: CVS: S1S2 Normal K/C/O- Epilepsy …..since 22 years 5) Raktavaha -Avishesh No/H/O- any major surgical illness 6) Mansavaha:Mansadaurbalya, Mansakshaya in both UL and LL, Muscle Samanya Parikshana: power decrease. Nadi:78/min regular Muscle power gradation : Agni: mandagni UL LL Rt 3/5 4/5 Lt 3/5 1/5 Akruti: sthaulya RR:18/min 93 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 7) Medovaha: Sphik-stana-udarlambanam and subcortical Rt temporal lobe may represent CNS involvement. 8) Asthivaha : Katishool EMG/NCS :- A primary muscle disorder 9) Majjavaha: Deep tendon reflexes with myotonic discharges. diminished 2D-Echo :- LVEF-60%, Normal valves, Deep tendon reflexes A Normal chamber size. K T B Rt + + + + Lt + + + + NIDANPANCHAK: 1.Hetu: Ahar: milk, curd, abhishyandiaahar like dosa, uttapa frequent use in meal(kaphavardhak) ,Bread, butter, biscuits All reflexes were diminished. etc.daily (vatavruddhikar) ,sheetjalsevan (freezed water)Vihar: lack of 10) Shukravaha: Avishesh11) Mutravaha: exercise, divasvapa Avishesh12) Svedavaha: Avishesh 2.Purvaroopa: katipradeshishool, INVESTIGATIONS: nidralpata CBC, ESR, LFT, RFT, Lipid profile, BSL : 3.Roopa: katishool, weakness in bilateral WNL (26-12-2013) UL and LL (mansadaurbalya), mansakshaya, Unable to walk, pain in calf CPK- 454 IU/L (26-12-13) muscle. MRI-lumbosacral joint (5-2-2010) diffuse 4.upashay: Snehanottarshoolupashaya. disc bulge at L3-L4, L4-L5, L5-S1 level identing thecal sac. Diagnosis according to Modern medicine: Myotonic dystrophy MRI-Brain (11-6-2012):- Tiny old ischemic changes involving bilateral frontoparietal Dosha-dushya vichar:Dosh: Vata, kapha white matter, Parieto-occipital white matter Dushya: 94 Mansa, Kandara, Snayu, ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Majja,Asthi ; Strotas: Avyayamat divaswapnat medyanam Mansavaha, Majjavaha, Asthivaha, cha atibhakshanat | Medovahini dushyanti varunyashcha 5.Samprapti: atisevanat || - Charak Vimansthan.5/24 Hetu:Abhishyandi ahar, kaphavatakarahari.e.milk,curd,frequent use CHIKITSA given: of bakery products,shitjalsevan,Lack of Tatroapisvayonivardhandravyopayo exercise,Divasvapa----kaphavatadushti----Jatharagnimandya gah ---- Dhatvagnimandya (pratikarah) | - Sushrutsutrasthan15/14 (specifically Mansadhatvagnimandya)------- 1) Sarvadehikchikitsa: A) Bahyachikitsa Mansavahastrotodushti and strotorodha-- B) Abyantarachikitsa ----Mansakshaya (Muscle atrophy) and Mansadaurbalya (diminished muscle A) Bahyachikitsa: power)-------Sarvangsnehanswedan for 14 days Majjavahastrotodushti(mastishkagatamaj jadushti) (diminished reflexes) ----- -Pindswed for 28 days Myotonicdystrophy -Shirodhara with brahmi+tiltail for Mansam sharirapushtim medasya 14 days cha | sushrut.sutrasthan. 15/7 Mansavaha strotas dushti karan: B) Abhyantarachikitsa : Abhishyandini bhojyani sthulani cha The treatment is given in following manner. guruni cha | -Arogyavardhinivati 2-2-2 for 7 days Mansavahini dushyanti bhuktam cha svapatam diva || -Chitrak +Pippali+ Vidang siddha -Charak gruta for deepan, pachan and mansagni Vimansthan.5/23 vardhan Medovaha dushti karan: 95 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ -Ashwagandhapak 2 gms BD for 1 month -Balaguduchyadikwath Lt + + + + ++ 20 ml BD for 1 month Lt + ++ ++ ++ 5.Pain/ - Cap. Palsinorm 2 BD for 1 month cramps +++ + in legs i) Shodhanchikitsa : 6.Muscle -Yogabasti with Dashmulaniruha power and tiltailanuvasan for 8 days UL UL LL LL Rt 3/5 Rt gradation ii)Yapanchikitsa : 4/5 -Karmabasti with Bala guduchyadiniruha Lt and Balatailaanuvasan for 30 days 1/5 4/5 Nidralpata Nidra 7. Nidra 4/5 3/5 Lt OBSERVATIONS AND RESULTS: Symptoms After treatment treatment 1.Backache 2.Walking Unable ability walk DISCUSSION: Mode of action of drugs: to Walk Kalpa without Contents Grip Decreased tendon reflex 1.Pindswed Almost strength normal A T K B A T Mode of action support 4.Deep 4/5 prakrut Before 3. 5/5 K Dashmula , Vatahar, bala, shothahar, ashwagandh mansa a, nirgundi , dhatu B milk, rice Rt + + Rt + + + ++ ++ balya bruhan karya 96 & ISBN 978-93-5173-179-3 http://www.ayurlog.com Vol. 2 ISSN 2320-7329 Issue- 2 April 2014 nd Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 2.Aarogyavar Kajjalli,loha Deepan, daruharidra, dhini vati bhasma, pachan, shatavari, tamra srotoshodh musta, bhasma,triph an patha,gokshu ala, r, kutaki,abhrak kantakarietc bhasmashilaj 7. Yogbasti for Makshik, Vatahar, atu, 8 days saindhav, shothahar, chitrak,gugg dashmula strotorodh ul kashaya,til a tail shodhan nashak, 3. Chitrakadi Chitrak+ Deepan, gruta vidang+ pachan, 8.Balaguduch Makshika, Balya, pippali mansagniv yadiBasti saindhav, vatanashak siddha gruta ardhan for15 days sneha: 4.Ashwagandh Ashwagandh a pak Balya, taila a, bala, ela, bruhan, c madhu, mansavard madanphala, han, pimpali, mansaposh indrayava an Cap Shallaki, Palsinorm asthisandh ankar, Kalka:yashti kapikacchu,et helpsin 5. til , Vatahar, Kashay: guggul, stimulant shuddha formajjadh kuchala, atu, Bala, Guduchi, Atibala, nirgundi, Rasna,Ashwa shunthi gandha, 6. Bala, Balya & Balaguduchya guduchi, bruhan for di kwatha devdaru, mansa sahachar, dhatu Aragvadha, Bilva, Devdaru, 97 Bruhana, yapana karya ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Sahachar, bruhan, balya, mansavardhan and Dashamula mansaposhankarya which is expected in treatment of this disease. Swayonidravya And will increase same dhatu is the principle for Mansarasa chikitsa. Aarogyavardhinivati contains Kwatha of dashmula, bala, kajjali, lohabhasma, abhrak bhasma, tamra ashwagandha, nirgundi, and kshir which is bhasma, guggulu , shilajatu, kutaki, chitrak boiled with rice is used for pindswed. This whichis deepan ,pachan, agnivardhan and is srotoshodhan byreducing dushta kapha. bruhankarya of mansadhatu. best chikitsa of for vatashaman, Chitrak, pippali and vidang are katu- During treatment, there was no tiktarasatmakdravya which are useful in convulsion episode , Nidra was prakrut, mansagnivardhan. patient feels relaxed mentally. Ashwagandhapak contains CONCLUSION: balyadravya which are mansa-majjaposhak. Thus from above case report we can Cap. Palsinorm is a proprietary confidently say that, Myotonic a good ayurvedic medicine which contains shuddhakuchala, Dystrophyhas which is stimulant to nerves, nervine tonic i. management which helps patient to improve e. majjadhatu. their daily routine. Balaguduchyadikwatha proprietary medicine which is ,useful Thus in combination with these for simple ayurvedic principles and kalpas a mansavardhan,and vatashaman. Basti tiltail is with use dashmulaniruha for the purpose difficult disease like Myotonic Dystrophy can be successfully treated when applied and correctly at right conditions. of srotoshodhan. After srotoshodhanbasti with REFERENCES: balaguduchyadiniruha with mansarasa and anuvasan with balataila is given for 98 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 1. SushrutSamhitaedited vaidyaAnantram by 3. Dravyagunavidnyan sharma, chaukhambaprakashan, ,Priyavatsharma Varanasi ,chaukhambaprakashan, edition 2008 2. CharakSamhita Varanasi,2006 of Agnivesha 4. Bhaishjyakalpanavidnyan, ,Drudhbala ,chaukhambaprakashan acharyasiddhinandanmishra, ,delhi 2006 chaukhambaprakashan 2006. Cite this article: AYURVEDIC MANAGEMENT OF MYOTONIC DYSTROPHY: A CASE REPORT Ketaki Jalinder Jadhav, Prerana P. Jawale Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2):91-99 99 Varanasi ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved Article_15 ______________________________________________________________________________________________________________________________________________________ ROLE OF SHIRODHARA IN NIDRANASH ___________________________________________________________________ Sujata Jadhav*1 ___________________________________________________________________ 1. Associate Professor P.G. Department of Kayachikitsa, CSMSS Ayurved College, Kanchanwadi, Aurangabad- 431002, Maharashtra, India. * Corresponding Author: [email protected] mobile-09271865835 ___________________________________________________________________ Keywords: Abstract: Nidranash, Shirodhara, Murdhataila,, Insomnia. Ayurveda has described three Upasthambas or healthy mind and body. Introduction: These Upasthambas are Aahara, Nidra Ayurveda ,Brahmacharya. Nidranash is one of the as healthy body and mind. This Swasthya mental health problems around the world. The modern treatment is not entirely satisfactory. Ayurveda has described for male shirobasti. and female Therefore patients this study Samhita Vrishya jaagare , brahmacharya. of Nidra In been stated as (Happiness), Pushtikar Balyakar (Strength), (Sexual Urges), Dnyanakar (Learning), Jeevankar (Life giving) [2].In this (Nidranash)]. Shirodhara is convenient for both nidra (Nourishment), effective in the described order [Vagbhatta Shirobasti aahar , sukhakara Murdhtaila are Abhyang,Sec,Pichu,Basti advocated depends on three Upastambha[1] importance murdhataila for Nidranash.The types of has has described Swasthya way Nidranash affects the body, mind as than well as soul. At present it is the foremost is mental health problem around the world and undertaken. commonest condition observed in both private and hospital practice. In the last few 100 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ decades human psyche has failed to cope (Preprocedure) and paschyatkarma (Post with rapid change of pattern of lifestyle and procedure). Seka that is Shirodhara satisfies very fast progress of technological and these criteria but the efficacy of Shirodhara industrial developments. In environmental is not properly known as far as literature on pollution, this subject is concerned. Therefore this stress and strain full life conditions, unlimited demands in secure old study is undertaken. age. The youth have adopted undesirable Hypothesis habits like smoking, alcohol, drug addiction. As a result the incidence of nidranash 1. In Nidranash while considering (Insomnia) has greatly multiplied in recent Vatvriddhi, Pittavriddhi as well as years. Kaphakshaya Til-Taila is Balya, [6] Vatanulomak . A vast number of researchers are 2. Shirodhara is sort of meditation trying to find better way of treating and which may be effective for stability managing Nidranash. Modern medicine has of mind and also for sleep. developed potent drugs for induction and 3. Indriya- Tarpan Karya of Murdha- maintenance of sleep but some of these drugs are found to be Taila was considered. carcinogenic, 4. Twacha teratogenic etc. Long term use of any such i.e Sparshnendriya i.e. Vatsthan and Mana are Sarvavyapak drug leads to addiction. Therefore modern was also considered. treatment is not entirely satisfactory. 5. Hence Vatchikitsa should also be Ayurveda has mentioned many lines of treatment like[3] ksheera, considered. madya, 6. Regarding mansarasa, dadhi, abhyanga, udvartana Ashayapakarshak-Gati ,snana, murdha-karna-akshi considerable. out of which Murdha taila [4] tarpana etc. Vatchikitsa is also (tarpana) is said to be most effective . Murdha taila has Aims and objectives: four types Abhyanga, Seka, Pichu, Basti[5] . To Study the role of Shirodhara in In finding appropriate management we must management of Nidranasha seek a way which has got long duration of action and minimal purvakarma 101 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Methods and materials: Group 2: 10 patients -with Placebo For the clinical study 40 patients in the After selection of patient detail history was department of kayachikitsa in Seth Ramnath taken Dharmarth Rugnalaya, Pune were taken. investigations and routine pathological The study was done in both levels in the and thorough physical examination was hospital i.e. in OPD as well as IPD level. done. 1. Patients having age of 20-60 yrs Patients were followed up daily the therapy. were only considered. 2. Patients of either sex were taken for Criteria of diagnosis: The diagnosis was the study. based mainly on the clinical presentation 3. Patients with history of Nidranash at of the patient. The following investigations least one month and also having were undertaken to exclude other pathology following signs and symptoms were to assess the condition of patient. Routine taken : blood investigations like HB, TC, DC, ESR, Angamarda(Bodyache) , PCV Shirogaurav (Heaviness in head), (Laziness), (Weight loss), carried out. Routine and microscopic urine examination was done. Akshigaurav (Heaviness in eyes), Karshya were Blood sugar was also done. Alasya Jrimbha(Yawning), Criteria for assessment of results: Moha(Confusion), The most of the signs and symptoms of Rukshata(Dryness), Nidranash Jadhya(Sluggishness), described in Ayurveda are subjective and to give the results objectively Glani(Sleepiness), and for statistical analysis multidimensional Bhrama(Giddiness), scoring system was adopted. This symptoms Apakti(Indigestion) [7]. score was obtained daily and the statistical Patients were divided into two groups as analysis was done at the end of the study follows: to assess the efficacy of treatment. Group 1: 30 patients: with Shirodhara 102 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ The scoring done was as follows: sleep Grade1 Mild degree of symptom duration Grade2 Moderate degree of Grade0 - 6-7hrs symptoms Grade1 - 5-6hrs Grade3 Grade2- 4-5hrs SHIRODHARA VIDHI [8] Grade3- 3-4hrs Preparation of Patients: Grade4 2-3hrs Grade5- 1-2hrs Grade6- 0-1hrs Severe degree of symptoms The patients selection was done as described in clinical study. Male patients were advised to remove scalp hair totally. All the patients were advised to wash hair before starting therapy. Awakenings Preparation of dhara-patra and table: Grade0 – No awakenings Dhara-patra – A copper pot of two Grade1 litres, broad at the neck and tapering at the 1-2times bottom. At the bottom a hole of 5 mm was Grade2 3-4times Grade3 5-6times made. A wick of gauze piece was introduced in the hole to adjust the dhara. The dhara-patra was hanged in the stand Grade4 with the help of sling.Table with soft bed 7-8times was kept. Table was adjusted in a way to Presence or absence of general symptoms collect oil. like Moha, Angamarda, Jadya, Glani, Preparation of drugs Shirogaurav, Akshigaurav, Alasya, Apakti, Rukshata, Krishata, Bhrama, were graded Til taila was taken one litre in as follows : quantity per patient. It was warmed first and Grade0 then Absence of symptoms 103 poured in Dhara-Patra . The ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ temperature of taila was maintained during Botanical name : Sesamum indicum. the therapy. Family: Pedalinancae. Pradhan karma Variety: Black seeds-it gives best quality of Patient was to lie in supine position oil .White seeds-richer in oil. Red/brown with neck extended. Two gauze pieces were seeds. kept on the eyes for preventing the taila from entering in the eyes. The distance between the wick in the hole and the properties[9]: Rasa- madhur-kashaya, Anurasa-tikta, Vipak- madhur, Prabhav-keshya patients head was kept 4 angula and the and Sanskarat sarva rogajeet, Guna-guru, snigdha. dhara was adjusted such that it will fall straight and continuously on forehead. The Actions- vatshamak, snehan, vedanashamak time of Dhara vidhi was 45 minutes ( and muhurta) per patient . The oil from head region was recollected in Pharmacological keshya. Seeds are laxative and emolients, dimulsent and nourishing after other pot as the particular sansakar the oil becomes shown in the photograph and was again warmed and repoured in dharapatra .The Uses: Til-taila is used widely as a base of therapy was given for seven days.The different medical oils. Local applications are procedure was carried out in vat-kala. useful in vatvikara wounds Maximum from growth of hair. It is a good medhya also. disturbances. Separate oil was used for each After different sanskara it can be used patient strictly. both isolation was done ways for gaining and proper weight and reducing the weight. Paschyat karma Chemical composion: seeds contain-50Remaining oil on head was smoothly 60% fixed oil[10] massaged on head. Patient was advised to wear scarf or cap while returning home to Analysis: 10 protect from cold or heat and also advised avoid travelling. Black seed Description of Til-taila 104 Moisture oil 2-5.2% 44.6-56.9% ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Red seed 45.7% 55.5% Markedly improved: 50% to 75% relief in the chief complaints and improvement in White seed 2-4.4% 44.9-58.2% sleeping hours upto 4 to 6 hours at night. (Bombay govt. agri.dept.bulletin) Improved : upto 50% relief in the chief complaints and improvement in sleeping Protein-22% hours. Carbohydrates-18% Unchanged : no improvement in chief Mucilage-4% complaints and sleeping hours. Woody fibers-4% Observation and Discussion: Nidranash is described in detail by Ash-4.8% Charak, Oil contents: 70% of liquid fats consisting Ashatangsangraha, Vagbhata, Sushruta. Charak has described Nidranash of glycerides of oleic and linolic acids and as 12-14% of solid fats stearin, palmitin and one of eighty[11] the Nanatmajvyadhis(harangadhra has quoted12 myristin. alpanidrata as one pittajananatmajvyadhis. Crystalline substances: sesamin and a of These the ancient authors have advocated various modalities phenol compound sesamol of treatments. Charak has described SnehChikitsa for Nanatmaj Vyadhis. Shirodhara Total effect of therapy: therapy with Til-Taila was selected for At the end of therapy the total effect treatment of Nidranash in this study. of therapy was assessed in the terms of complete remission, markedly improved, The various causes implicated in the improved and unchanged with the following aetiology of Nidranash in this study are criteria: Manastap, Prakriti, Dhatukshaya, Vatvriddhi, Karya, Vikar. Complete remission: 75% to 100% relief in The pathogenesis of Nidranash is the chief complaints and improvement in described as – Vatprakop (Bhay, Shok, sleeping hour upto 6 hours at night. 105 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ Chinta, Kam), Pittaprkop (Krodh, Irshya). Til-Taila is Madhur, Tikta, Kashaya, (Charaka Chikistasthana adhyaya 28.) Vatghna. Hence it is effective in the treatment of Nidranash. The effectiveness The predominant symptoms of treatment was assessed by grading the observed in this study were alsya(82.5%), angamarda(65%), severity of various symptoms through the rukshata(60%), therapy. The effect of Shirodhara in shirogaurav (55%), Bhrama(50%). Along Nidranash can be due to Vatshamak action with these malavastambha (constipation) of Til-Taila and also due to Nidrakar action was seen in 40% of patients. of Murdha-Taila. 40 patients of Nidranash were In this study following observations were selected for this study. The maximum noted – number of patients were in age group of 40 to 50 and 50 to 60 years. These two age 1. Increase in total sleeping period. groups were the commonest age group of 2. Increase in uninterrupted sleep incidence of Nidranash. period. 3. Decrease in number of awaking Both male and females are about equal in episodes. numbers in the ratio of 1:1 4. Increase feeling of well-being. 5. Quite and cool feeling in eyes. For the study patients were divided into two groups. The score of severity of Nidranash was graded separately for total sleep period Group 1: Shirodhara group and for number of awakening episodes before and after the treatment for group 1 Group 2: Control group and group 2. Group 1 was given Shirodhara with TilTaila daily for seven days. Group 2 was The Patients on placebo therapy given placebo therapy of two capsules didn’t show any improvement in total sleep containing wheat-flour at bed time for seven period as well as in pattern of sleep. In this days. study only one patient on placebo therapy showed some improvement in sleep pattern. 106 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ This may attributed to the psychological symptoms at the end. Only Angamarda, aspect of the patient. Akshigaurav, Shirogaurav showed negligible change in few patients. But as seen above the Shirodhara therapy group has shown significant change This supports that Shirodhara with Til-Taila in both i.e for total sleep period and Pattern was responsible for the improvement in (Swaroop) of sleep. In group 1 total sleep Rupas period changed from grade5 to grade2. So shirogaurav. Maximum change in gradation the sleep hours increased from 1 to 2 hrs to was seen for these Rupas. Moderate change 4 to 5 hrs. in gradation was seen in Rupas likem moh, like angamarda, akshigaurav, jadya, glani, bhrama, alasya, jrimbha, The change in sleep pattern observed rukshata. There was no change in gradation was from grade 3 to grade 1 i.e. the number of karshya. This proves that Shirodhara was of awakening decreased from 5 to 6 times to responsible for the change of severity in 1 to 2 times. group1. This is conclusive that Shirodhara From above observation it is seen was responsible for the change in score of that maximum patients benefitted from the severity of Nidranash in group1. And hence therapy are seen in markedly improved Shirodhara with Til-Taila is proved to be an group. effective mode of treatment for Nidranash. Conclusion: For reaffirmation of the above result it was proved in this study that five patients Shirodhara with Til-Taila is effective in group1 on sedative drugs such as in the treatment of Nidranash. Diazepam, Alprazolam were able to stop the medication after 4th or 5th day of therapy and References: showed improvement in the period as well 1. Agnivesh charak samhita vidyotini hindi as pattern of sleep. commentary part-1, Vd kashnath pande, Vd. On comparing the score of both the Gorakhnath Chaturvedi, Chokhambha bharti groups it can be seen that in Group2 there academy,Varanasi, Sutrasthan, Chapter 1135, p.227, Ed.21st. was no significant change in severity of 107 ISBN 978-93-5173-179-3 http://www.ayurlog.com ISSN 2320-7329 Issue- 2 April 2014 nd Vol. 2 Ayurlog: National Journal of Research in Ayurved Science A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved ______________________________________________________________________________________________________________________________________________________ 2. Agnivesh charak samhita vidyotini hindi 7. Vagbhta Ashtanghridaya sarvangsunder of commentary part-1 Vd kashnath pande, Arundatta, Ayurved rasayana of Hemadri by Vd.Gorakhnath Chaturvedi Chokhambha Dr A. Kunte and K. Shastri Naware, hindi bharti commentary Chokhambha Krishna Das academy, Varanasi, Sutrasthan st Chapter21-36 p.418 .Ed.21 . academy, Ed 2009 Sutrasthan adhyay, 7-64 3. Vagbhta Ashtanghridaya, Sarvangsunder of p.143, Ed, 2009. Arundatta, Ayurved rasayana of Hemadri by 8. Sahasrayog by Kendriy ayurved avam Dr A.Kunte and K. Shastri Navre, hindi sidhha commentary Chokhambha Krishna Das Dharakalp 13, P-521 academy, Sutrasthan adhyay, 7-66, p.143, with samhita, commentary by nyanychandrika Nibandhasangraha Dallanacharya panjika Vidyotini Brahmasankara and of parishad (1990), 9. Acharya Bhavmishra, Bhavprakash Samhita Ed, 2009 4. Sushruta anusandhan hindi commentary Misra, by Chaukhambha Sansrit Bhavan, Varanasi, 2012. P-152. Sri 10. Bhavprakash Nighantuyukt part first Gayadasacharya by Vd Jadhavji Trikamji, (purvardha), Choukhomba Sanskrit bhavan Chokhambha Varanasi, Shree Brahma Shankar Mishra, Botanist, th Shree Rupalalji Vaishya dhanya varga, page orientalia, Sharirsthan Adhyay, 4-43p.359, 4 Ed 1980 no.651 5. Sharangdhar samhita, Jeevanprada hindi 11. Indiam Materia Medica by Dr. K. M. commentary by S. Shrivastav, Chokhamba Nadkarni, Vol. 1. Page No. 1126-29, Orientalia, Samhita Uttarkhanda Adhyay- Bombay Popular Prakashan, Reprint 1992, nd 11, 121 p. 446, 2 Ed, 1988 6. Agnivesha, Dr. 12. Shrangdhar, Jeevanprada hindi commentary Gorakha Chaturvedi, Chaukhamba Bharti by S. Shrivastav, Choukhamba Orientalia, Academy Charak revised and enlarged by A.K. Nadkarni. Varanasi, Samhita edition by th 10 -2039, Sharangdhar samhita Poorva nd khanda, Adhyay-7, p.100,119 , p.108 2 Ed, 1998. Sutrasthana Adhyay 27-30, p. 530 Cite this article: ROLE OF SHIRODHARA IN NIDRANASH Sujata Jadhav Ayurlog: National Journal of Research in Ayurved Science-2014; 2(2): 100-108 108