84th EAS CONGRESS
Transcription
84th EAS CONGRESS
84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria k oo B e m m Progra www.eas2016.kenes.com EAS 2016 AT YOUR FINGERTIPS Download the App for the Full Congress Experience Search “EAS 2016” Your all-in-one guide for the duration of the Congress: 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria · Access the programme and venue maps · Bookmark your preferred sessions and read about your favorite speakers · Receive important notifications from the organisers · Learn about exhibitors and sponsors, accreditation, and much more k oo B e m m Progra Organised by Rue François-Versonnex 7 1207 Geneva, Switzerland Tel: +41 22 501 7420 Fax: +41 22 906 9140 Email: [email protected] 84 EAS CONGRESS th CONTENTS Welcome Letter Dear friends and Colleagues, 3 Committees4 The European Atherosclerosis Society 6 About Innsbruck 8 EAS Keynote Lecture 9 The Anitschkow Prize 10 Young Investigator Awards 11 General Information 13 CME Accreditation 16 Information for Presenters 19 Poster Area Map 22 Programme at a Glance 24 Congress Floor Plan 28 Hall Name Eulogy of Distinguished Scientists 30 Scientific Programme Sunday, May 29, 2016 35 Monday, May 30, 2016 41 Tuesday, May 31, 2016 57 Wednesday, June 1, 2016 73 Science at a Glance Presentations 81 Poster Presentations, Monday May 30, 2016 99 Poster Presentations, Tuesday, May 31, 2016 137 Index of Authors 181 Recognition, Acknowledgements and Commercial Support 217 On behalf of the European Atherosclerosis Society (EAS) and the Austrian Atherosclerosis Society (AAS) we are delighted to welcome you to Innsbruck for the 84th EAS Congress. The congress committees have been working hard on preparing a programme of scientific excellence that will excite and inform the European and Global Atherosclerosis communities. We are particularly proud to announce the certainly inspiring Keynote Lecture by Nobel laureate Michael S. Brown entitled “How genes control cholesterol” and invaluable contributions by outstanding plenary speakers. The comfortable atmosphere of the congress venue and its impressive setting will provide a unique meeting place for high-level interdisciplinary exchange of newest research highlights and effective networking among participants from more than 70 countries from across the world. The congress will be held at Congress Innsbruck, located next to the scenic river Inn and in walking distance to the city centre and all major hotels. Innsbruck is one of the most beautiful cities in the Alps, surrounded by impressive mountain peaks. Another attraction, of course, are the superb Tyrolean culinary highlights that will be offered during the unique Social Programme and throughout the meeting. Finally, for those with a few days to spare, there are many interesting opportunities to visit Innsbruck’s cultural highlights before and after the congress. The 84th EAS congress is accompanied by an International Satellite Symposium on Lp(a) two days ahead of the main congress, again bringing together world experts in this small but exciting and emerging field of an extraordinary atherogenic lipoprotein. On behalf of the organising committee, we welcome you to Innsbruck for a memorable and inspiring congress. Acknowledgements219 2 Industry Sponsored Sessions 222 Educational Grant 228 Exhibition Information 229 List of Sponsors and Exhibitors 231 Alberico L. Catapano EAS President Geesje Dallinga-Thie Chair, Programme Scientific Committee Seppo Ylä-Herttuala Co-Chair, Programme Scientific Committee Hans Dieplinger Congress Chair Florian Kronenberg Congress Chair 3 84 EAS CONGRESS th COMMITTEES FACULTY LIST Afonyuskin Taras, Austria Alitalo Kari, Finland Armitage Jane, UK Assmann Gerd, Germany Averna Maurizio, Italy Banach Maciej, UK Besseling Joost, The CONGRESS CHAIRs Hans Dieplinger, Austria Florian Kronenberg, Austria EAS EXECUTIVE COMMITTEE Alberico L. Catapano, Italy, President Olov Wiklund, Sweden, Vice President Netherlands SCIENTIFIC PROGRAMME COMMITTEE Geesje Dallinga-Thie, The Netherlands, Chair Denmark Petri Kovanen, Finland, Secretary & Award Committee Chair Seppo Ylä-Herttuala, Finland, Co-Chair Boulanger Chantal M., France Brouwer Ingeborg A., Eric Bruckert, France The Netherlands Jan Borén, Sweden, Treasurer Alberico L. Catapano, Italy Lale Tokgözoglu, Turkey, President Elect Hans Dieplinger, Austria Christoph J.Binder, Austria Jörg Heeren, Germany Geesje Dallinga-Thie, The Netherlands Dimitris Kardassis, Greece Børge Nordestgaard, Denmark Florian Kronenberg, Austria Arnold von Eckardstein, Switzerland Chris Packard, UK Michal Vrablík, Czech Republic Erik Stroes, The Netherlands M. John Chapman, France, Past President Arnold von Eckardstein, Switzerland LOCAL ORGANISING COMMITTEE Counselling Members Hans Dieplinger, Innsbruck, Congress Chair Wolfgang Schneider, Austria Florian Kronenberg, Innsbruck, Congress Co-Chair Christoph Binder, Vienna Benjamin Dieplinger, Linz Christoph Ebenbichler, Innsbruck Bernhard Föger, Bregenz Gerhard Kostner, Graz Dagmar Kratky, Graz Gerhard Kostner, Austria CONGRESS COMMITTEE Marja-Ritta Taskinen, Finland, Chair Wolfgang Schneider, Vienna Herbert Stangl, Vienna Ernst Steyrer, Graz Gerd Utermann, Innsbruck Rudolf Zechner, Graz de Meyer Guido R.C., Belgium Després Jean-Pierre, Canada Dieplinger Benjamin, Austria Dieplinger Hans, Austria Ebenbichler Christoph J., Austria The Netherlands Andreas Ritsch, Innsbruck APPRECIATION AND THANKS We would like to thank the reviewers of the submitted abstracts for their valuable help and assistance. The Netherlands Mach Francois, Switzerland Maegdefessel Lars, Sweden März Winfried, Germany Malik Vasanti, USA Mangelsdorf David, USA Manolio Teri, USA Marsche Gunther, Austria Martinez Laurent O., France Matsuzawa Yuji, Japan McCormick Sally, Suhre Karsten, Qatar Stuling Thomas, Austria Taskinen Marja-Riitta, Finland Tawakol Ahmed, USA Titze Jens M., Germany Tokgözoglu Lale, Turkey Tschöp Matthias, Germany Ulmer Hanno, Austria Utermann Gerd, Austria van Gaal Luc, Belgium von Eckardstein Arnold, The Netherlands Chris Packard, UK Ruth Prassl, Graz The Netherlands Netherlands Danilo Norata, Italy Hans Dieplinger, Austria Lambert Gilles, France Lamina Claudia, Austria Laufs Ulrich, Germany Letourneur Didier, France Luetjohann Dieter, Germany Ley Klaus, USA Lichtenstein Alice H., USA Lutgens Esther, Pechlaner Raimund, Austria Piepoli Massimo, Italy Poirier Steve, Canada Prassl Ruth, Austria Ray Kausik K., UK Reaven Peter D., USA Ripatti Samuli, Finland Ritsch Andreas, Austria Rudling Mats, Sweden Ryan Robert O., USA Sanjana Neville, USA Schmid Johannes, Austria Schneider Markus, Germany Schneider Wolfgang, Austria Scharbagl Hubert, Austria Scheja Ludger, Germany Schunkert Heribert, Germany Seed Mary, UK Stangl Herbert, Austria Steinhagen-Thiessen Elisabeth, Germany Steyrer Ernst, Austria Stojakovic Tatjana, Austria Stroes Erik, Brown Mark J., USA Brown Michael, USA Bruckert Eric, France Bujo Hideaki, Japan Caligiuri Giuseppina, France Carmeliet Peter, Belgium Catapano Alberico, Italy Chapman M. John, France Colhoun Helen, UK Dallinga-Thie Geesje, El-Osta Assam, Australia Farinaro Eduardo, Italy Ferri Nicola, Italy Föger Bernhard, Austria Fu Jingyuan, Jan Borén, Sweden Bernhard Paulweber, Salzburg 4 Binder Christoph J. , Austria Borén Jan, Sweden Bossano Prescott Eva, Hoffmann Michael, Germany Humphries Steve, UK Hunt Steve, Qatar Jauhainien Matti, Finland Kararigas Georgios, Germany Kardassis Dimitris, Greece Karpe Fredrik, UK Koenig Wolfgang, Germany Kollerits Barbara, Austria Kostner Gerhard, Austria Kotseva Kornelia, UK Kovanen Petri, Finland Kratky Dagmar, Austria Kronenberg Florian, Austria Kuivenhoven Jan Albert, The Gaetano Carlo, Germany Gaudet Daniel, Canada Gordts Philip, USA Graham Ian, Ireland Herz Joachim, USA Heeren Jörg, Germany Hersberger Martin, Switzerland Hobbs Helen, USA Hoefer Imo, The Netherlands New Zealand Moschetta Antonio, Italy Moulin Philippe, France Müller Thomas, Austria Nicholls Stephen, Australia Norata Giuseppe Danilo, Italy Nordestgaard Børge, Denmark Öörni Katariina, Finland Packard Chris, UK Parini Paolo, Sweden Pasterkamp Gerard, The Netherlands Switzerland Vrablik Michal, Czech Republic Watts Gerald, Australia Wiklund Olov, Sweden Willeit Peter, UK Ylä-Herttuala Seppo, Finland Yvant-Charvet Laurent, France Zambon Alberto, Italy Zechner Rudolf, Austria Zelcer Noam, The Netherlands Zimmermann Robert, Austria Paulweber Bernhard, Austria 5 84 EAS CONGRESS th The European Atherosclerosis Society The European Atherosclerosis Society (EAS) was founded in 1964 with the aim of “advancing and exchanging knowledge concerning the causes, natural history, treatment and prevention of atherosclerotic disease”. For more than 50 years the Society’s expertise has been used to teach clinicians how to manage lipid disorders and how to prevent atherosclerosis. By offering to our members access to educational materials, and opportunities to take part in Congress and courses, and by providing a forum in which new developments can be discussed, EAS contributes to the development of knowledge in the field, and ultimately to the improved treatment of persons with cardiovascular disease and lipid disorders. In recent years the Society has made a particular effort to recruit young scientists and clinicians also from other related disciplines. The European Atherosclerosis Society’s goal is to provide a framework for concerted scientific and clinical discussion of new developments in basic research, diagnosis and therapy of atherosclerosis. What we do – at a glance • EAS is active in the publication of Guidelines and Consensus Position Papers, and its official Journal is Atherosclerosis. Through a regular series of Featured Commentaries EAS puts into perspective topical issues of relevance to our members. • The Society organizes an annual Congress for approximately 2000 delegates, and runs a programme of Advanced Courses for both basic scientists and clinicians. •EAS Academy is the Society's online e-Learning resource, containing a range of educational material and self-teaching programmes. • EAS is co-organiser of the European Lipoprotein Club (ELC) annual Scientific meeting. • EAS coordinates the FH Studies Collaboration, working to establish an international registry of observational studies on FH. Why should I become an EAS member? Stay well informed with EAS publications EAS membership makes it easier for those working in the field to stay abreast of the latest developments in the field. In addition to access to the Society's own publications of Consensus position papers and Guidelines, EAS membership includes complimentary access to Atherosclerosis Journal (worth ca. 300 €), and members receive by email newsletters and featured commentaries on topical issues. Interact with leading experts in the field at EAS Congress The participants at EAS annual Congress are world leaders in atherosclerosis research and clinical practice, and the size and format of the Congress lends itself to networking and interaction. EAS members are encouraged to submit their findings as an abstract to Congress, where they can participate at significantly reduced registration fee (savings of up to 100 € compared to non-member fees). Apply for grants and prizes as an EAS member EAS members may apply for the Society's travel grants to attend Congress, and, where eligible, may apply for the Society's Prizes. Great value membership benefits at affordable annual subscription rates EAS' aim is to provide access to learning that will help our members to manage lipid disorders and to prevent and treat atherosclerosis. We keep our annual membership subscription rates low – 40 € (persons over 35) or 20 € (persons 35 or younger) – so that as many as possible can afford to become members. How to become an EAS member If you're not an EAS member and would like to become one, you should complete the application form and pay the annual subscription fee. Once your application is approved, and the subscription payment processed, you become eligible for membership benefits for one year at www.eas-society.org. Continue your professional development with EAS educational activities - Advanced courses & EAS Academy EAS membership offers opportunities to deepen your theoretical skills and/or practical knowledge, which you can then apply in your own research or clinical practice. The Society organises educational activities such as Advanced Courses (many CME accredited by EBAC), and offers a wealth of online learning material, such as webcasts, videos and quizzes, on the Society's educational platform, EAS Academy. As an EAS member, you have access to the very latest uploaded material, EAS Academy's Premium content. 6 7 84 EAS CONGRESS th EAS KEYNOTE LECTURE ABOUT innsbruck Innsbruck is the capital city of the federal state of Tyrol in western Austria. It is located in the Inn Valley at the junction with the Wipptal (Sill River), which provides access to the Brenner Pass, some 30 kilometers (19 mi) south of Innsbruck. Located in a broad valley between high mountains, it is an internationally renowned winter sports centre. Innsbruck serves as an ideal place for skiing in winter, and mountaineering in summer. There are several ski resorts around Innsbruck as well as nearby, which include the Axamer Lizum, Patscherkofel, Igls, Seefeld, Tulfes and Stubai Valley. The city of Innsbruck is suffused with the spirit of the Habsburg dynasty. The Habsburgs’ legacy in Innsbruck is sumptuous and palatial majestic and has left many architectural landmarks in the city. The Keynote Lecture at EAS Congress 2016 is given by Michael S. Brown, Paul J. Thomas Professor of Molecular Genetics and Director of the Jonsson Center for Molecular Genetics at University of Texas Southwestern, Dallas, USA. Dr. Brown and his long-time colleague, Dr. Joseph L. Goldstein, are recognised as the discoverers of the low density lipoprotein (LDL) receptor, which controls the level of cholesterol in blood and in cells. Drs. Brown and Goldstein have received many awards for this work, including the U.S. National Medal of Science and the Nobel Prize for Medicine or Physiology in 1985. Working together, Drs. Brown and Goldstein showed that familial hypercholesterolaemia is caused by genetic defects in the LDL receptor, which disrupt the normal regulation of cholesterol metabolism. Their studies led to the elucidation of the mechanism by which this receptor carries LDL particles into cells through coated pits and coated vesicles. These LDL receptor studies provided clear evidence for selective uptake of macromolecules into cells, giving rise to the concept of receptor-mediated endocytosis. More recently, study of another genetic disease called Niemann-Pick C (NPC), has provided insights into how cholesterol is transported from one organelle to another, which underlie the consistency in cholesterol concentration in the plasma membrane. Extensive studies showed that both the NPC1 and NPC2 proteins have the capacity for binding LDL cholesterol. Whereas binding of cholesterol to NPC2 is rapid, occurring within minutes, binding to NPC1 is extremely slow, requiring several hours to reach equilibrium. However, this process can be accelerated when cholesterol is delivered by NPC2. Based on these findings, it was proposed that NPC2 extracts cholesterol from LDL in the lysosome and then transfers it to the N-terminal domain of membrane-bound NPC1 for insertion into the lysosomal membrane, currently being tested in the laboratory of Professor Brown. The work of Drs. Brown and Goldstein has not only been the stimulus for new thinking about cholesterol homeostasis, but also has led to the development of new concepts in biology. Specifically, these include selective sorting of proteins within the plasma membrane, a prerequisite for receptor-mediated endocytosis; receptor-mediated endocytosis and receptor recycling; and, finally, the concept of feedback regulation of receptors. Michael Brown graduated in 1962 from the College of Arts and Sciences of the University of Pennsylvania, with chemistry as his major subject, and subsequently obtained his M.D. degree in 1966 at the same university. He was an intern and resident at the Massachusetts General Hospital, where he met Joseph L. Goldstein, a fellow intern; the two established the friendship and mutual respect that led to their long-term scientific collaboration. Dr. Brown subsequently completed a postdoctoral fellowship at the National Institutes of Health, before moving to UT Southwestern, becoming Professor in 1976. The remainder of this story has been instrumental in changing how hypercholesterolaemia is managed, and paving the way for innovative new therapeutic agents targeting LDL cholesterol. 8 9 84 EAS CONGRESS th THE ANITSCHKOW PRIZE YOUNG INVESTIGATOR AWARDS The Anitschkow prize recipient 2016 is Professor Peter Carmeliet, Professor at the Katholieke Universiteit Leuven (Leuven, Belgium). These annual awards are presented by EAS for outstanding publications by young scientists in the field of Atherosclerosis The Anitschkov lecture entitled Endothelial Cell Metabolism: A Novel Player in Atherosclerosis? Basic Principles and Therapeutic Opportunities will be part of the Congress Opening Ceremony. p r o f e ss o r P e t e r C arm e li e t Peter Carmeliet is a physician and professor at the Katholieke Universiteit Leuven (Leuven, Belgium). He is former director (20082015) of the Vesalius Research Center, VIB - KU Leuven and is heading the Laboratory of Angiogenesis and Vascular Metabolism at the VRC. His research interests are vasculogenesis, angiogenesis, and vascular endothelial growth factors. His research group has sought to elucidate the molecular basis of angiogenesis with the aim of translating their findings to therapeutic concepts and ultimately novel treatments. Latest findings indicate that the efficacy of current antiangiogenic therapy in cancer is limited by intrinsic refractoriness and acquired drug resistance. To overcome this problem, his research team pioneered the study of endothelial cell metabolism during vessel sprouting. Professor Carmeliet is the recipient of numerous awards, including InBev-Baillet Latour health prize (2010), Ernst Jung-Priz für Medizin (2010), the Blaise Pascal Medal in Medicine and Life Sciences by the European Academy of Sciences (2011), the Münster Heart Center Award (2015), and award of the Noble title of Baron, granted by King Filip of Belgium (2015). 10 st e v e p o iri e r In 2003, Steve joined the team of Dr. Nabil Seidah at the Clinical Research Institute of Montreal the same year the laboratory published the identification of PCSK9 and its link to familial hypercholesterolemia. Over the years, he actively designed and performed key experiments as well as collaborated with international researchers to accomplish important studies in the highly competitive field of PCSK9 biology in cardiovascular diseases. Cited by more than 850 publications, those manuscripts have questioned and revisited published papers that supported the fact that PCSK9 had only one target and that it was acting exclusively via an extracellular route. He was the first to show that PCSK9 has other important targets towards LDLR family members and revealed the existence of an intracellular route for PCSK9-induced LDLR degradation. In addition, he also made many other significant contributions in the field of PCSK9 such as the identification of the two known natural inhibitors of PCSK9 namely AnxA2 (extra-hepatic) and GRP94 (hepatic) now used as precursors for the design of lipid-lowering agents with high therapeutic potentials. He also showed that the cytosolic adaptor AP-1A is directly implicated in the intracellular trafficking of Niemann-Pick type C proteins and revealed the first evidence and mechanism by which the cancer drug 5-Azacytidine favorably perturbs lipid and cholesterol metabolism. Together with his great scientific partner Dr. Gaétan Mayer (CSO), he is the co-founder and CEO of Monogenic Pharmaceuticals a Montreal Heart Institute-based biotech primarily developing 4 distinct unprecedented and highly innovative therapeutic pipelines to lower circulating LDLCholesterol and cardiovascular diseases by specifically targeting PCSK9. 11 84 EAS CONGRESS th GENERAL INFORMATION YOUNG INVESTIGATOR AWARDS VENUE Congress und Messe Innsbruck GmbH Rennweg 3 6020 Innsbruck, Austria www.cmi.at J o o st B e ss e ling Dr. Besseling started Med School at the University of Amsterdam (the Academic Medical Center) in 2004 and obtained his medical degree in 2012. Subsequently, he started his PhD research under the guidance of Prof. Kastelein, Dr. Hovingh and Dr. Hutten. He worked on studies focused on different aspects of familial hypercholesterolemia and published in highly cited peer reviewed journals, such as Lancet and JAMA. He specifically focused on the diagnosis, consequence and treatement of FH and as such showed that FH patients are relatively protected from diabetes mellitus. Moreover, he developed a new prediction model for carriership of an FH mutation, and investigated the consequence of CETP inhibition in these patients. In January 2016, he started his residency to become a board certified specialist in internal medicine, and in October 2016, he will defend his PhD thesis on familial hypercholesterolemia. OFFICIAL LANGUAGE The official language of the Congress is English. All presentations will be made in English. CLOTHING Clothing is informal for all occasions. REGISTRATION DESK HOURS The Registration Desk will be situated at the North Entrance, ground level of the convention center, as follows: Sunday, May 29 10:00 – 21:00 Monday, May 30 07:30 – 19:40 Tuesday, May 31 08:00 – 18:30 Wednesday, June 1 08:00 – 12:30 EXHIBITION OPENING HOURS Sunday, May 29 Monday, May 30 Tuesday, May 31 Wednesday, June 1 17:30 – end of Welcome Reception 10:00 – 17:30 10:00 – 17:30 10:00 – 12:30 CONGRESS NAME BADGE Upon registration you will receive your name badge. You are kindly requested to wear your badge during all sessions and events. EAS 2016 App Install the EAS 2016 interactive mobile App to your smartphone and portable devices to access all the Congress information you could need during the Congress: • See the overview of sessions, speakers and exhibitors • Create your own programme for the event, including bookmarking the sessions you wish to attend • Receive real-time updates Download the EAS App now to enhance your congress experience! (available on the App Store or Google Play). 12 13 84 EAS CONGRESS th EAS 2016 E-Book Cloak Room EAS 2015 Final Programme E-Book is available online and can be viewed and downloaded at: www.eas2016.kenes.com This e-book offers a ‘green alternative’ to the printed programme book, provides delegates a convenient and enjoyable way to access congress content on the move and is designed to provide a user friendly interface on any mobile device. EAS is dedicated to implementing innovative and environmentally-friendly technology. The programme book can be downloaded as a PDF file from the congress website. A cloak room will be available for participants on Wednesday, June 1st at the Innfoyer. REFRESHMENTS Please do not leave bags or suitcases unattended at any time, whether inside or outside the session halls. Hotels strongly recommend that you use their safety deposit boxes for your valuables. Coffee and refreshments will be served to Congress participants in the Exhibition Area from May 29-June 1, as indicated in the Programme. Cash Bars will be available next to the Exhibition Area. internet access WiFi is available for congress participants throughout the public areas. In order to log in please use the following user name and password: User name: eas-2016 Password: eas-2016 Free internet and email facilities will be available in the exhibition area during the exhibition opening hours only. Congress abstracts will also be available for viewing from these stations. Please be considerate of fellow participants when using these facilities. CONGRESS ABSTRACTS The congress abstracts will be published online in the Atherosclerosis Journal following the congress. MOBILE PHONES AND PHOTOGRAPHY LIABILITY AND INSURANCE The Congress Secretariat and Organisers cannot accept liability for personal accidents or loss of or damage to private property of participants. Participants are advised to take out their own personal travel and health insurance for their trip. SAFETY AND SECURITY WEBCASTING A selection of sessions will be webcast and will be available on the Society website after the Congress. CONGRESS ORGANISERS 84th EAS Congress Rue François-Versonnex 7, 1207 Geneva, Switzerland Tel: +41 22 501 7420 Fax: +41 22 906 9140 E-mail: [email protected] Participants are kindly requested to keep their mobile phones switched off in session halls and refrain from taking pictures during sessions. SMOKING POLICY The 84th EAS Congress is a Non-Smoking event and participants are requested to refrain from smoking in the venue. 14 15 84 EAS CONGRESS th CME ACCREDITATION EDUCATIONAL OBJECTIVES EBAC Accredited Educational Programme After participating in this educational event, learners should be able to: EBAC Accredited Educational Programmes will be taking place during the Congress as follows: • Address individual needs in compliance with their Continuous Professional Development (CPD) plan. • Exchange ideas and knowledge in the field of Atherosclerosis and related cardiovascular conditions across continents, institutions, and individuals. • Discuss the innovative new therapeutic agents targeting LDL cholesterol. • Identify possible programmatic collaborations to more effectively address regional, national and local responses to Atherosclerosis around the world and overcome barriers that limit access to prevention, care and services. • Discuss the latest scientific advantages in the field of Atherosclerosis and related cardiovascular conditions. • Summarise the latest research outcomes in the field of Atherosclerosis and related cardiovascular conditions. TARGET AUDIENCE Specialists in the field of atherosclerosis, clinical chemistry, diabetes, endocrinology, primary care and more. ACCREDITATION STATEMENT AND CREDIT DESIGNATION European Board for Accreditation in Cardiology (EBAC) An application was made to the European Board for Accreditation in Cardiology (EBAC) for CME accreditation of this event. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). American Medical Association (AMA) Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www. ama-assn.org/go/internationalcme. Royal College of Physicians and Surgeons of Canada Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada. For more • EBAC Accredited Educational Programme: Diet and prevention of cardiovascular disease. Symposium at EAS 2016 Innsbruck Sunday, May 29, 2016, 14:00-15:30 This session is supported by an unrestricted educational grant from BASF, Raisio and Unilever. • EBAC Accredited Educational Programme: Gene therapy and lipoprotein lipase deficiency. Symposium at EAS 2016 Innsbruck Sunday, May 29, 2016, 14:00-15:00 This session is supported by an unrestricted educational grant from Chiesi. • EBAC Accredited Educational Programme: Gene therapy and lipoprotein lipase deficiency. Symposium at EAS 2016 Innsbruck Monday, May 30, 2016, 13:00-14:00 This session is supported by an unrestricted educational grant from Meda (Rottapharm). • EBAC Accredited Educational Programme: Low HDL high triglyceride, diabetic dyslipidaemia. Symposium at EAS 2016 Innsbruck Tuesday, May 31, 2016, 13:00-14:00 This session is supported by an unrestricted educational grant from Mylan. • EBAC Accredited Educational Programme: Lysosomal Acid Lipase Deficiency. Symposium at EAS 2016 Innsbruck Tuesday, May 31, 2016, 13:00-14:00 This session is supported by an unrestricted educational grant from Alexion. In compliance with EBAC/ EACCME guidelines, all speakers/ chairpersons participating in this programme have disclosed or indicated potential conflicts of interest that might cause a bias in the presentations. The Organizing Committee is responsible for ensuring that all potential conflicts of interest relevant to the event are declared to the audience prior to the CME activities. CREDIT BREAKDOWN Day Maximum Credits Sunday, May 29 Monday, May 30 Tuesday, May 31 Total Credits: 2 1 2 5 information, visit: www.royalcollege.ca. CREDIT BREAKDOWN Day Maximum Credits 16 Monday, May 30 Tuesday, May 31 Wednesday, June 1 Total Credits: 6 6 3 15 17 84 EAS CONGRESS th INFORMATION FOR PRESENTERS TO RECEIVE YOUR CME/CPD CERTIFICATE ORAL PRESENTATIONS The CME/CPD certificate will be available after completing the online evaluation and credit claiming procedure. The process takes about 5 minutes. We thank you for your feedback as it is an important part of CME/CPD accreditation and helps improve future educational offerings. Data Presentation: Before June 29, 2016: 1. Access the online system via any of the following Please note that web browsers Mozilla Firefox 2.X or higher, or Google Chrome are recommended - Visit the CME/CPD Accreditation page on the event website - Follow the link in the email sent at the end of the event 2. Complete the anonymous online evaluation 3. Complete the credit claim form and submit 4. The CME/CPD certificate will be available for download; fill-in and retain for your personal records DISCLOSURE AND RESOLUTION OF PERSONAL CONFLICTS OF INTEREST In accordance with CME/CPD accreditation criteria and standards for commercial support to ensure balance, independence, objectivity, and scientific rigor, those in control of the educational content must disclose potential or actual conflicts of interest. Disclosure information is evaluated and conflicts of interest resolved. Disclosure is made to participants prior to the activity. Participants will be asked on the evaluation to assess the objectivity and independence of the event. INDUSTRY SUPPORT DISCLOSURE This event is supported, in part, by funding from industry. All support is managed in strict accordance with CME/CPD accreditation criteria and standards for commercial support. Appropriate acknowledgement of all supporting organizations is made in the Programme guide, on the event website, and with signage during the event. Disclosure is made to participants prior to the activity. 18 Aegerion Pharmaceuticals Akcea Therapeutics Alexion Amgen BASF Chiesi Denka Seiken European FH Network FH Score Fuji Film/ Sonosite Merck MSD IBL Kaneka Pharma Kowa Meda Pharma Mercodia Mylan Numares Pfizer Raisio Randox Regeneron Sanofi Unilever Wisepress A speakers’ ready room will be available throughout the entire Congress for speakers. The room is located on the 1st Level (Maximilian). If using a PowerPoint presentation (or any other PC based application, such as PDF), please note you need to bring it on USB Memory stick and load it on one of the Congress computers in the Speakers’ Ready Room at least 1 hour before the start of the session. The recommended format for PPT presentations is 16:9. Please make sure to prepare your presentation accordingly. Please note that the Congress computers in the session halls are being supplied with Office 2010 (at least). If combining video films with PowerPoint, please make sure to check it in the session hall where your lecture is taking place during the break prior to your session, at least 30 minutes before the start of the session - even after checking it in the Speakers’ Ready Room. Alternatively you may supply your own laptop computer. In such a case please confirm that it has a VGA socket for external signal and come to check it first in the Speakers’ Ready Room as soon as you arrive and later on in the session hall where your lecture is taking place during the break prior to your session, at least 30 minutes before the start of the session. Important note for Apple Mac users: In order to use MAC presentations on a PC compatible computer please note that you need to prepare it according to the instructions below, before bringing it to the Speakers’ Ready Room: 1.Use a common font, such as Arial, Times New Roman, Verdana etc. (special fonts might be changed to a default font on a PowerPoint based PC). 2.Insert pictures as JPG files (and not TIF, PNG or PICT - these images will not be visible on a PowerPoint based PC). Alternatively you may use your own Macintosh laptop computer. In such a case please confirm you provide it with a VGA adaptor for external signal, advise the operators in the Speakers’ Ready Room about it as soon as you arrive and later on test it in the session hall where your lecture is taking place during the break prior to your session, at least 30 minutes before the start of the session 19 84 EAS CONGRESS th SCIENCE AT A GlANCE PRESENTATIONS EAS is proud to have Science at a Glance E-Poster sessions that will be located in the Exhibition area, providing the unique opportunity for convivial scientific discussions and exchange. For further details please refer to the Overview of these Sessions. OVERVIEW OF SCIENCE AT A GLANCE E-POSTER SESSIONS Session I, Monday, May 30, 2016 Session Topic Session Chair 13:00-14:00 E-Poster Station 14:00-15:00 Session Chair E-Poster Station Poster # Experimental Cadiovascular Medicine II Matti Jauhiainen, Finland Station A SaG097-SaG104 Immunity and Atherosclerosis Giuseppina Caligiuri, France Station B SaG105-SaG112 Emerging Aspects in Pharmacological Treatment of Primary and Secondary Dyslipidemia Benjamin Dieplinger, Austria Station C SaG113-SaG120 Vascular Biology III Joachim Herz, USA Station D SaG121-SaG128 Lipids and Lipoproteins Jörg Heeren, Germany Station A SaG001-SaG008 Vascular Biology I Guido de Meyer, Belgium Station B SaG009-SaG016 Genetic, Omics and in silico Approaches Neville Sanjana, USA Station C SaG017-SaG024 POSTER PRESENTATIONS CV Risk Factors and Atherosclerosis I Yuji Matsuzawa, Japan Station D SaG25-SaG032 Posters will be on display in 2 shifts. Please check the Scientific Programme to see the exact poster board number, date, and time of the poster discussion groups. Session II, Monday, May 30, 2016 14:00-15:00 Session Topic Session Chair E-Poster Station Poster # Experimental Cadiovascular Medicine I Paolo Parini, Sweden Station A SaG033-SaG040 Nutrition, Nutraceuticals and Cardiovascular Disease Alice H. Lichtenstein, USA Station B SaG041-SaG048 Pharmacology of Dyslipidemia Maurizio Averna, Italy Station C SaG049-SaG056 Imaging in Vascular Dysfunction and Myocardial Infarction Wolfgang Koenig, Germany Station D SaG057-SaG064 Session III, Tuesday, May 31, 2016 20 Poster # Session IV, Tuesday, May 31, 2016 Session Topic 13:00-14:00 Session Topic Session Chair E-Poster Station Poster # CV risk factors and Atherosclerosis II Winfried März, Germany Station A SaG065-SaG072 Vascular Biology II Herbert Stangl, Austria Station B SaG073-SaG080 Insulin Resistance, Diabetes, Metabolic Syndrome and Obesity Gerald Watts, Australia Station C SaG081-SaG088 Hypertension, Liver and Chronic Renal Disease TBA Station D SaG089-SaG096 The organisers are not responsible for any posters that have not been removed by the end of sessions on Wednesday, June 1. Poster Shift I Posters may be mounted from 17:30 on Sunday, May 29, 2016 and should remain on display until Monday, May 30, 2016 at 18:30. Poster Shift II Posters may be mounted from 08:30 on Tuesday, May 31, 2016 and should remain on display until Wednesday, June 1, 2016 at 12:30. Authors are asked to actively participate in both the poster sessions on the day in which their poster was allocated to. Poster sessions will take place on Monday, May 30 from 13:00-14:00, 17:00-18:00 and Tuesday, May 31 from 13:00-14:00, 17:00-18:00. 21 84 EAS CONGRESS th Poster Area Map POSTER OVERVIEW Please note that posters of Abstract presenters that were not registered to the congress by the deadline were not allocated poster boards. Such abstract presenters are requested to approach the poster help desk to be allocated an available poster board on-site. Poster Shift I – Monday, May 30, 2016 Session Time Topic 13:00-14:00 Vascular Biology: Endothelium and Smooth Muscle Cells Poster Board 001 – 044 Vascular Biology: Macrophages, Inflammation, Immunity 045 - 088 Vascular Biology: Myocardial Infarction, Stroke, Peripheral Vascular 089 - 134 Disease 17:00-18:00 Vascular Biology: Immune Disease and Cardiovascular Pathologies 135 - 142 Lipoproteins and Lipid Metabolism: ApoB Containing Lipoproteins 143 - 163 Lipoproteins and Lipid Metabolism: Lipoprotein Metabolism 164 - 187 Lipoproteins and Lipid Metabolism: Lp(a) 188 - 210 Lipoproteins and Lipid Metabolism: HDL 211 - 245 CVD Risk Factors 246 - 320 Poster Shift II – Tuesday, May 31, 2016 Session Time Topic 13:00-14:00 Metabolic Abnormalities and Atherosclerosis: Diabetes 001 - 056 Metabolic Abnormalities and Atherosclerosis: Adipose Tissue 057 - 066 To: Nikolai N. Anitschkow (Tirol) Poster Board Metabolic Abnormalities and Atherosclerosis: Kidney 067 - 081 Metabolic Abnormalities and Atherosclerosis: NASH and Liver 082 - 090 Abnormalities Dyslipidemias: Dyslipidemias, Screening and Treatment To: Nikolai N. Anitschkow (Tirol) 17:00-18:00 091 - 167 Dyslipidemias: Treatment 168 - 199 Dyslipidemias: Coagulation 200 - 210 Dyslipidemias: Endothelial Dysfunction 211 – 220 Genetics, Nutrition, Biomarkers: Genetics, Gene Regulation 221 - 259 Genetics, Nutrition, Biomarkers: Nutrition 260 - 298 Genetics, Nutrition, Biomarkers: Biomarkers 299 - 333 Genetics, Nutrition, Biomarkers: Guidelines and Miscellaneous 334 - 344 Please note that posters of abstract presenters that were not registered to the Congress by the deadline were not allocated poster boards. Such abstract presenters are requested to approach the poster help desk to be allocated an available poster board on-site. 22 23 84 EAS CONGRESS th Programme at a Glance Monday, May 30, 2016 Exhibition & Posters Area Plenary Session Workshop Science at a Glance Session Young Investigators Session Oral Communication Session Company Sponsored Session EBAC Accredited Session Poster Walk Session Other Social Event 08:30-10:30 10:30-11:00 12:00-13:30 13:30-14:00 Workshop 1.1 Novel Aspects of Pathogenesis in Atherosclerosis EBAC Accredited Educational Programme Diet and Prevention of Cardiovascular Disease 14:00-15:00 EBAC Accredited Educational Programme Gene Therapy and Lipoprotein Lipase Deficiency 12:30-15:00 11:00-11:45 Advanced Clinical Seminar Debate on Statin Associated Muscle Symptoms (SAMS) - A Problem for Clinicians or a Problem with Clinicians? Workshop 3.1 Novel Therapies Break, Exhibition and Poster Viewing 13:00-14:00 Science at a Glance Session I 13:00-14:00 Poster Walk Session I 14:00-15:00 Science at a Glance Session II 13:00 – 14:30 Educational Symposium Supported Session Not included in the CME/CPD programme 13:00 – 14:30 Educational Symposium Supported Session Not included in the CME/CPD programme EAS- ESC Joint Workshop Sex differences in Cardiovascular Diseases Workshop 1.2 Therapeutic and Diagnostic Targeting of the Arterial Wall Educational Symposium Supported Session Not included in the CME/CPD programme 15.00-16:30 Opening Ceremony, including the Anitschkow Lecture 16:30-17:00 Coffee break, Exhibition and Poster Viewing 17:00-18:30 17:00-18:00 Poster Walk Session II Break Welcome Reception 18:40-19:40 24 Wilhelm Auerswald (Strassburg) 11:45-12:30 Advanced Clinical Seminar Role of Nutrition in Disease Pathology Break 18:00-19:45 19:45– 20:45 Wilhelm Auerswald (Strassburg) Break 16:00-17:30 17:30-18:00 Carl von Rokitansky (Brussel) Workshop 2.1 Lipoproteins and Extracellular Matrix 12:30-13:30 Meet the Expert Supported Session Not included in the CME/CPD programme 14:00-15:30 15:30-16:00 Karl Landsteiner (Innsbruck) Carl von Rokitansky (Brussel) Coffee Break, Exhibition and Poster Viewing 11.00-12.30 Nikolai N. Anitschkow (Tirol) Karl Landsteiner (Innsbruck) Plenary Session: Integrative Approach in Atherosclerosis Sunday, May 29, 2016 Exhibition & Posters Area Nikolai N. Anitschkow (Tirol) Young Investigator Session Vascular Biology and Inflammation Young Investigator Session Lipids and Lipoproteins Metabolism 13:00-14:00 EBAC Accredited Educational Programme Nutraceuticals with Lipid Lowering: Who Can Benefit? Workshop 2.2 Adipose Tissue – Liver Axis 15:00-15:45 Late Breaking: Basic Science 15:45-16:30 Young Investigator Award Session Young Investigator Session Clinical Epidemiology and Pharmacology Oral Communication Session Vascular Biology Keynote Lecture 25 84 EAS CONGRESS th Tuesday, May 31, 2016 Exhibition & Posters Area 08:30-10:30 10:30-11:00 Karl Landsteiner (Innsbruck) Carl von Rokitansky (Brussel) Wilhelm Auerswald (Strassburg) Plenary Lecture: Lipid Biology, New Insights Exhibition & Posters Area 08:30-10:30 Coffee Break, Exhibition and Poster Viewing 11:00-12:30 12:30-15:00 Wednesday, June 1, 2016 Nikolai N. Anitschkow (Tirol) Workshop 1.3 Cellular Stress Response in Atherosclerosis Workshop 2.3 Gut- Liver Axis ICCR-EAS Joint Session Management of Cardiometabolic Risk; Where Do We Stand? Workshop 3.2 Vascular Aging and Atherothrombosis 13:00-14:30 Educational Symposium Supported Session Not included in the CME/CPD programme 13:00-14:00 EBAC Accredited Educational Programme Low HDL High Triglyceride, Diabetic Dyslipidaemia 13:00-14:00 EBAC Accredited Educational Programme Lysosomal Acid Lipase Deficiency 14:10-14:55 Supported Session Not included in the CME/CPD programme 14:10-14:55 Supported Session Meet the Expert Not included in the CME/CPD programme 15:00-16:30 EAS Initiatives Update Session (open to all) Advanced Clinical Seminar Economics and Guidelines/ Technology of the Future Break, Exhibition and Poster Viewing 13:00–14:00 Science at a Glance Session III 13:00-14:00 Poster Walk Session III 14:00–15:00 Science at a Glance Session IV 15.00-16:30 14:00-14:45 Supported Session Special Lecture Not included in the CME/CPD programme Workshop 3.3 Genetics in Risk Factor Prevention and Treatment Late Breaking: Clinical Science 10:30-11.00 11:00-12:30 Karl Landsteiner (Innsbruck) Carl von Rokitansky (Brussel) Wilhelm Auerswald (Strassburg) Fritz Pregl (Freiburg) Workshop 4.4 New Guidelines on Prevention of Cardiovascular Disease in Clinical Practice Workshop 2.4 Novel Role of Lipoprotein Receptors Plenary Session: Future Therapeutic Challenges Coffee Break, Exhibition and Poster Viewing Workshop 1.4 Inflammation Immunity and Atherosclerosis Workshop 3.4 Biology of CVD Risk 16:30-16:50 EAS General Assembly 26 16:30-17:00 Coffee Break, Exhibition and Poster Viewing 17:00-18:30 17:00-18:00 Poster Walk Session IV Workshop 3.5 Epigenetics and Gene Regulation Oral Communication Session Imaging, Biomarkers Oral Communication Session Intracellular Lipid Young Investigator Session Novel pathways in 27 84 EAS CONGRESS th CONGRESS FLOOR PLAN 28 Level 0 Level 2 Level 1 Level 3 29 84 EAS CONGRESS th HALL NAME EULOGY OF DISTINGUISHED SCIENTISTS Nikolai N. Anitschkow (1885-1964) Professor of the Department of Pathological Physiology of the Military Medical Academy St. Petersburg, Russia In 1913, experimental pathologist Dr. Nikolai N. Anitschkow showed that simply feeding to rabbits purified cholesterol dissolved in sunflower oil induced vascular lesions closely resembling those of human atherosclerosis, both grossly and microscopically. Controls fed with only the sunflower oil showed no lesions. It is fair to say that this paper marked the beginning of the modern era of atherosclerosis research. Dr. Anitschkow was not only a keen-eyed structural pathologist and a careful experimentalist; he thought in terms of function and time-related pathogenesis. However, the landmark studies by Dr. Anitschkow were largely rejected at the time. An important reason for this was that the findings were inconsistent with the prevailing view of atherosclerosis. It was generally accepted to be an inevitable accompaniment of aging (the “senescence hypothesis”). If the full significance of his findings had been appreciated at the time, we might have saved more than 30 years in the long struggle to settle the cholesterol controversy. In honor of Dr. Nikolai N. Anitschkow, the “Anitschkow Prize in Atherosclerosis Research” awarded annually by the EAS recognizes outstanding research in the field of atherosclerosis and linked metabolic disturbances. 30 Karl Landsteiner (1868-1943) Karl Landsteiner, Austrian pathologist, studied medicine at the University of Vienna. In 1896 he became an assistant in the Hygiene Institute at Vienna where he was interested in the mechanisms of immunity and in the nature of antibodies. From 1898 till 1908 he held the post of assistant in the University Department of Pathological Anatomy in Vienna, in 1911 he became Professor of Pathological Anatomy in the University of Vienna. He showed that the cause of poliomyelitis could be transmitted to monkeys by injecting into them material prepared by grinding up the spinal cords of children who had died from this disease. His work laid the foundations of our knowledge of the cause and immunology of poliomyelitis. Landsteiner made numerous contributions to both pathological anatomy, histology and immunology, all of which showed, not only his meticulous care in observation and description, but also his biological understanding. But his name will no doubt always be honoured for his discovery in 1901 of the blood groups, for which he was given the Nobel Prize for Physiology or Medicine in 1930. In 1875 Landois had reported that, when man is given transfusions of the blood of other animals, these foreign blood corpuscles are clumped and broken up in the blood vessels of man with the liberation of haemoglobin. In 1901-1903 Landsteiner pointed out that a similar reaction may occur when the blood of one human individual is transfused, not with the blood of another animal, but with that of another human being, and that this might be the cause of shock, jaundice, and haemoglobinuria that had followed some earlier attempts at blood transfusions. His suggestions, however, received little attention until, in 1909, he classified human blood into the now well-known A, B, AB, and O groups and showed that transfusions between individuals of groups A or B do not result in the destruction of new blood cells and that this catastrophe occurs only when a person is transfused with the blood of a person belonging to a different group. Earlier, in 1901-1903, Landsteiner had suggested that, because the characteristics which determine the blood groups are inherited, the blood groups may be used to decide instances of doubtful paternity. In 1922, he accepted a post in the Rockefeller Institute for Medical Research in New York. It was here that he did further work on the blood groups which greatly extended the number of these groups, and studied bleeding in the new-born, leading to the discovery of the Rh-factor in blood, which relates the human blood to the blood of the rhesus monkey. 31 84 EAS CONGRESS th Karl Baron von Rokitansky (1804-1878) Austrian pathologist whose endeavours to establish a systematic picture of the sick organism from nearly 100,000 autopsies—30,000 of which he himself performed—helped make the study of pathological anatomy a cornerstone of modern medical practice and established the New Vienna School as a world medical centre during the latter half of the 19th century. A professor of pathological anatomy at the Vienna General Hospital, he inspired the Bohemian student Ignaz Semmelweis, later a martyr to the cause of antiseptic medical practice, to take up the study of medicine and afterward supported him in his struggle to eliminate childbed fever by cleaning up Europe’s maternity wards. First to detect bacteria in lesions of malignant endocarditis, an often rapidly fatal inflammation of the membrane lining the inner walls of the heart, Rokitansky created the basis for a differentiation of lobar pneumonia (originating in the lower lobe of the lung) and lobular pneumonia, or bronchopneumonia (originating in the finer subdivisions of the branched bronchial tree). He made a fundamental study of acute yellow atrophy of the liver (now known as Rokitansky’s disease), established the micropathology of pulmonary emphysema (a condition of the lung characterized by enlarged air spaces separated from the terminals of the bronchial tree), and first described spondylolisthesis, the forward displacement of one vertebra over another. 32 Wilhelm Auerswald (1917-1981) Wilhelm Auerswald, Austrian physiologist, graduated from medical school at the University of Vienna in 1940. Auerswald became assistant at the Physiological Institute of the University of Vienna in 1944. Under the later-appointed Director Carl Schwarz-Wendl Auerswald could finish his habilitation in Physiology in 1950 and was established in 1968 as the successor to Gustav Schubert. His scientific work includes 370 publications in the fields of physiology and pathology of blood proteins, nutrition, thrombosis, atherosclerosis, aerospace- and work physiology. It was Auerswald’s concern to make his research results available for practical medicine; he provided valuable pioneering work in the fields of plasma replacement, productions of vaccines (first Poliomyelitis vaccine in Austria) and immunoglobulins (first intravenous application). His blood coagulation studies gained high international reputation. In his teaching Auerswald was anxious to consider physiology as medical basic science with strong and immediate reference to the bedside; he also succeded in renaming his workplace into the Department of Medical Physiology. Its translation and adaptation of the “Textbook of Physiology” 33 Fritz Pregl (1869-1930) Fritz Pregl, Austrian physiologist and chemist, studied medicine at the University of Graz and received his M.D. In 1894, he became assistant lecturer for physiology and histology under Alexander Rollett, taking over the chair when Rollett died in 1903. During this time Pregl also acquired a thorough knowledge of all branches of chemistry under the guidance of Professor Skraup. He started investigating the components of albuminous bodies and the analysis of bile acids. His work, however, was handicapped by the lack of sufficient starting materials and this fact impelled him to look for methods requiring smaller amounts when making quantitative analyses of elements in compounds. The years 1910-1913, whilst professor at the University of Innsbruck, were almost entirely devoted to developing the method of quantitative organic micro-analysis. Pregl continued this work when he was recalled to Graz in 1913. Initially Pregl’s scientific work had been mainly in the fields of physiology and physiological chemistry; later he turned to the study of the constitution of chemical compounds, in particular the investigation of bile acids. By 1912 he was able, by using his own methods of quantitative micro-analysis, to make measurements of carbon, hydrogen, nitrogen, sulphur, and halogen, using only 5-13 mg of starting materials with results as accurate as those obtained by macro-analysis. Later he perfected his techniques so that as little as 3-5 mg were adequate. Pregl also contributed a number of micromethods for measuring atomic groups and developed a series of apparatus, including a sensitive microbalance, necessary for his work. The greatest honour was the award of the Nobel Prize for Chemistry by the Swedish Academy of Sciences in 1923. The Nobel Committee pointed out that it was not for a discovery, but for modifying and improving existing methods that Pregl was awarded the prize. Following the Nobel Prize for Chemistry in 1923, chemists from all over the world came to the MedicoChemical Institute in Graz to study Pregl’s techniques of quantitative organic micro-analysis under his guidance. 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria e m m a r g o r P c fi i Scient ay 29, 2016 Sunday, M 34 www.eas2016.kenes.com Sunday, May 29, 2016 Sunday, May 29, 2016 12:30 - 13:30 C. von Rokitansky Hall Industry Symposium: Meet the Expert Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 13:30 - 14:00Exhibition & Poster Area Break 37 Sunday, May 29, 2016 14:00 - 15:30 C. von Rokitansky Hall EBAC Accredited Session: Diet and Prevention of Cardiovascular Disease 14:00 - 15:00W. Auerswald Hall EBAC Accredited Session: Gene Therapy and Lipoprotein Lipase Deficiency This educational programme is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hourof external CME credit(s); Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). This educational programme is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hourof external CME credit(s); Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). EAS have independently organised all matters related to this 90-minute Programme, including content and presenters. We acknowledge financial support, in the form of an educational grant, received from BASF, Raisio and Unilever in support of the Programme. Chair: E. Bruckert (France) 14:00 SHOULD SATURATED FAt BE TARGETED FOR The PREVENTION Of CARDIOVASCULAR DISEASE? 1 2 A.H. Lichtenstein (USA) 14:20 SUGAR INTAKE AND CARDIOVASCULAR DISEASE - SHOULD IT BE The NEXT FIGHT TO DECREASE CVD? 3 10 Chair: M. Averna (Italy) 11 14:00 GENETIC SEVERE HYPERTRIGLYCERIDEMIA 14:15 GENETIC THERAPY FOR LIPOPROTEIn LIPASE DEFICIENCY 12 4 13 E. Stroes (Netherlands) 14:45 CASE REPORT J. Chapman (France) 15:00 ROLE Of MICROBIOTA ON CARDIOVASCULAR DISEASE Chair: J. Borén (Sweden) A. Zambon (Italy) J.P. Després (Canada) 14:40 PLANT STEROL AND STANOLS AND CARDIOVASCULAR DISEASE. IMPACT Of ENRICHED FOODS AND CHOLESTEROL-LOWERING DRUGS EAS have independently organised all matters related to this 60-minute Programme, including content and presenters. We acknowledge financial support, in the form of an educational grant, received from Chiesi in support of the Programme. 14 E.S. Thiessen (Germany) 14:45 CONCLUSION AND DISCUSSION 15 5 J. Fu (Netherlands) 6 15:30 - 16:00Exhibition & Poster Area J.P. Després (Canada) 7 Break J. Chapman (France) 8 J. Fu (Netherlands) 9 15:20 PANEL DISCUSSION A.H. Lichtenstein (USA) 16:00 - 17:30N. Anitschkow Hall Industry Symposium: Company Sponsored Session Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 17:30 - 18:00Exhibition & Poster Area Break 38 39 18:00 - 19:45N. Anitschkow Hall Plenary: Opening Ceremony, including the Anitschkow Lecture Chair: A. Catapano (Italy) 16 Chair: H. Dieplinger (Austria) 17 Chair: F. Kronenberg (Austria) 18 18:00 WELCOME FROM EAS PRESIDENT 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria 19 A. Catapano (Italy) 18:03 WELCOME FROM IAS PRESIDENT 20 Y. Matsuzawa (Japan) 18:06 WELCOME FROM MAYOR Of INNSBRUCK 21 C. Oppitz-Plörer (Austria) 18:09 WELCOME FROM PRESIDENT Of The MEDICAL UNIVERSITY Of INNSBRUCK 22 H. Fritsch (Austria) 18:12 WELCOME FROM AUSTRIAN ATHEROSCLEROSIS SOCIETY & CONGRESS CHAIR 23 H. Dieplinger (Austria) 18:15 ACKNOWLEDGEMENT Of JOURNAL EDITOR-IN-CHIEF, PROFESSOR STEVE HUMPHRIES 24 A. Catapano (Italy) 18:20 MUSICAL INTERLUDE 25 18:30 INTRODUCTION TO ANITSCHKOW PRIZE WINNER 26 A. Catapano (Italy) 18:35 ANITSCHKOW LECTURE: ENDOTHELIAL CELL METABOLISM: A NOVEL PLAYER In ATHEROSCLEROSIS? BASIC PRINCIPLES AND THERAPEUTIC OPPORTUNITIES 27 P. Carmeliet (Belgium) 19:25 CLOSING REMARKS AND INVITATION TO WELCOME RECEPTION 28 F. Kronenberg (Austria) 19:30 MUSICAL INTERLUDE 29 19:45 - 20:45Exhibition Area Welcome Reception 40 e m m a r g o r P c fi i Scient ay 30, 2016 Monday, M www.eas2016.kenes.com Monday, May 30, 2016 Key journals in Monday, May 30, 2016 Cardiology 8:30 - 10:30N. Anitschkow Hall Plenary: Integrative Approach in Atherosclerosis 8:30 Chair: A. Catapano (Italy) 30 Chair: H. Dieplinger (Austria) 31 GENETIC PROTECTION FROM CORONARY ARTERY DISEASE: The ROLE Of ABCG5 AND ABCG8 32 H. Hobbs (USA) International Journal of Cardiovascular Medicine, Surgery, Pathology and Pharmacology 9:00 25 Thrombin Generation and Platelet Reactivity at Editorial 41 Utilization of Statins: Guiding Principles and the New United States Guidelines Hennekens, C.H.; Gelb, I.J. (Boca Raton, Fla.) Editorial Comments 13 Systemic Inflammatory Response following Transcatheter Aortic Valve Implantation Paraskos, J.A. (Worcester, Mass.) 51 Hyperthyroid Atrial Fibrillation: Does It Matter for Stroke Risk? Poulin, M.-F.; Doukky, R. (Chicago, Ill.) Hospital Discharge and 6-Month Outcome after the Acute Coronary Syndrome in Diabetic and Nondiabetic Patients Kuliczkowski, W.; Szewczyk, M.; Kaczmarski, J.; Sztohryn, E.; Greif, M.; Pres, D. (Zabrze); Fortmann, S.D. (Towson, Md.); Poloński, L. (Zabrze); Serebruany, V. (Towson, Md.) 34 Assessment of Characteristics of Neointimal Hyperplasia after Drug-Eluting Stent Implantation in Patients with Diabetes Mellitus: An Optical Coherence Tomography Analysis Tian, F.; Chen, Y.; Liu, H.; Zhang, T.; Guo, J.; Jin, Q. (Beijing) 9:30 from Cellular Senescence via a Paracrine Mechanism Zhang, Y. (Suzhou); Wang, D. (Haerbin); Cao, K.; Chen, M. (Nanjing); Yang, X.; Tao, Y. (Suzhou) Review LEADING The WAY TO GENETICS AND PHARMACOGENOMICS In The CLINIC 34 T. Manolio (USA) 54 Autoantibodies to Oxidized Low-Density Lipoprotein Coronary Interventions: Pathogenesis, Risk Factors, Outcome, Prevention and Treatment 33 H. Schunkert (Germany) 43 Rat Induced Pluripotent Stem Cells Protect H9C2 Cells 62 Contrast-Induced Nephropathy in Percutaneous GWAS FOR CORONARY ARTERY DISEASE in Patients with Aortic Regurgitation: Association with Aortic Diameter Size Shimoni, S.; Bar, I.; Zilberman, L.; George, J. (Rehovot) Aurelio, A.; Durante, A. (Milan) Novel Insights from Clinical Experience Original Research 10:00 EPIGENETICS In ATHEROSCLEROSIS 9 Transcatheter Aortic Valve Implantation for a Failed 1 Allitridin Reduces IKr Current by Disrupting the Trafficking of Human Ether-à-Go-Go-Related Gene Channels Li, G.; Cheng, G.; Wu, J.; Ma, S.; Zhang, A.; Han, W.; Sun, C. (Xi’an) Bio-Bentall in Patients with Marfan Syndrome Beigel, R.; Siegel, R.J.; Kahlon, R.S.; Jilaihawi, H.; Cheng, W.; Makkar, R.R. (Los Angeles, Calif.) 35 A. El-Osta (Australia) 15 Synergistic Restoring Effects of Isoproterenol and Magnesium on KCNQ1-Inhibited Bradycardia Cell Models Cultured in Microelectrode Array Kim, S.K.; Pak, H.-N.; Park, Y. (Seoul) 10:30 - 11:00Exhibition & Poster Area Editor-in-Chief U. Pohl (Munich) An invaluable aid in understanding and treating heart disease A source of current research Cardiology features: • First reports on original clinical, preclinical and fundamental research • ‘Turning Basic Research into Clinical Success’ • ’Clinical Trial Design’ • Topical comprehensive reviews in selected areas of cardiovascular disease • ‘Editorial Comments’ The Journal of Vascular Research publishes original articles and reviews of scientific excellence in vascular and microvascular biology, physiology and pathophysiology. The scope of the journal covers a broad spectrum of vascular and lymphatic research, including vascular structure, vascular function, haemodynamics, mechanics, cell signalling, intercellular communication, growth and differentiation. www.karger.com/crd www.karger.com/jvr Coffee Break, Exhibition & Poster Viewing KI16241 Editor-in-Chief J.S. Borer (New York, N.Y.) 43 Monday, May 30, 2016 11:00 - 12:30N. Anitschkow Hall 11:00 - 12:30 Workshop 1.1: Novel Aspects of Pathogenesis in Atherosclerosis Workshop 2.1: Lipoproteins and Extracellular Matrix Chair: C.J. Binder (Austria) 36 Chair: S. Ylä-Herttuala (Finland) 37 11:00 BEYOND VASCULAR INFLAMMATION: RECENT ADVANCES In UNDERSTANDING ATHEROSCLEROSIS 38 K. Ley (USA) 11:25 B-CELLS AND ATHEROSCLEROSIS 39 C.J. Binder (Austria) 11:50 REGULATORY T CELLS FROM PATIENTS WITH ATHEROSCLEROSIS HAVE ENHANCED SUPPRESSION FUNCTION DUE TO INCREASED EFFECTOR/ RESTING RATIO AND PRO-INFLAMMATORY SKEWING 40 I.E. Dumitriu, P. Baruah, J.C. Kaski (United Kingdom) 12:03 CONTROL Of ATHEROSCLEROSIS BY AN APOE RECEPTOR-DEPENDENT NEUROMODULATOR41 J. Herz (USA) 12:16 DYNAMIN-RELATED PROTEIn 1 INHIBITION REDUCES OSTEOGENIC DIFFERENTIATION INDUCED TYPE 1 COLLAGEN SECRETION AND PREVENTS HUMAN VASCULAR CELL CALCIFICATION M. Rogers, N. Maldonado, J. Hutcheson, C. Goettsch, M. Aikawa, E. Aikawa (USA) K. Landsteiner Hall Chair: J. Borén (Sweden) 43 Chair: P. Gordts (USA) 44 11:00 POSTPRANDIAL HYPERLIPIDEMIA, ENDOTHELIAL DYSFUNCTION AND CARDIOVASCULAR RISK: FOCUS ON INCRETINS 45 P.D. Reaven (USA) 11:30 The ROLE Of PROTEOGLYCANS In HEPATIC TRIGLYCERIDE-RICH LIPOPROTEIn METABOLISM: ROLE Of ACOCIII AND APOAV 46 P. Gordts (USA) 12:00 INCREASED LIPOPROTEIn BINDING TO ARTERIAL PROTEOGLYCANS AND NORMAL MACROPHAGE CHOLESTEROL EFFLUX CAPACITY DEFINE The PRO-ATHEROGENIC FEATURE Of CKD DYSLIPIDEMIA 47 M. Pedrelli, P. Stenvinkel, M.E. Minniti, K. Emma, A. Dikkers, S. Ebtehaj, M. Gomaraschi, P. Barany, A.R. Qureshi, G. Camejo, B. Lindholm, K. Oörni, U. Tietge, L. Calabresi, E. Hurt-Camejo, P. Parini (Sweden) 12:15 BROWN AND BEIGE ADIPOCYTE ACTIVITY CONTROLS METABOLIC FLUX THROUGH The HDL COMPARTMENT 48 N. Schaltenberg, A. Bartelt, J. Clara, A. Worthmann, C. Lisa M., R. Franz, H. Markus, N. Stefan K., S. Ludger, J. Heeren (Germany) 42 11:00 - 11:45 C. von Rokitansky Hall Advanced Clinical Seminar 4.1: Debate on Statin Associated Muscle Symptoms (SAMS) - A Problem for Clinicians or a Problem with Clinicians? Chair: C. Packard (United Kingdom) 11:00 LESSONS FROM CLINICAL EXPERIENCE 49 50 U. Laufs (Germany) 11:20 LESSONS FROM CLINICAL TRIALS 51 J.M. Armitage (United Kingdom) 11:40DISCUSSION 44 52 45 Monday, May 30, 2016 11:45 - 12:30 C. von Rokitansky Hall Workshop 4.2: Role of Nutrition in Disease Pathology 11:00 - 12:30W. Auerswald Hall Workshop 3.1: Novel Therapies Chair: E. Bruckert (France) 53 Chair: F. Mach (Switzerland) 58 Chair: J.M. Titze (Germany) 54 Chair: D. Gaudet (Canada) 59 11:45 ROLE Of SODIUM In ATHEROSCLEROSIS 55 J.M. Titze (Germany) 12:05 SATURATED FAt In The DIET: GOOD OR BAD? 60 F. Mach (Switzerland) 56 I. Brouwer (Netherlands) 12:25DISCUSSION 11:00 ANTI-INFLAMMATORY INTERVENTIONS VERSUS INTENSIVE LDL LOWERING 57 11:25 COMPARATIVE EFFECTS Of CHOLESTERYL ESTER TRANSFER PROTEIn INHIBITION, STATIn AND EZETIMIBE THERAPY ON ATHEROGENIC AND PROTECTIVE LIPID FACTORS: The ACCENTUATE TRIAL 61 S. Nicholls, K. Ray, C. Ballantyne, L. Beacham, D. Miller, G. Ruotolo, J. Riesmeyer (Australia) 11:50 A NOVEL COMBINATORIAL NON-VIRAL VECTOR TO TREAt FAMILIAL HYPERCHOLESTEROLAEMIA (FH) 62 A. Kerr, L. Tam, M. Cioroch, A. Hale, G. Douglas, K. Channon, R. Wade-Martins (United Kingdom) 12:03 CURRENT STATUS-PHASE I TRIAL Of CELL-TRANSPLANTATION THERAPY WITH ALLOGENEIC ADIPOSE TISSUE-DERIVED MULTILINEAGE PROGENITOR CELLS In SEVERE FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS UNDERGOING LDL-APHERESIS 63 M. Koseki, S. Ayami, T. Okada, T. Kobayashi, M. Asaji, R. Kawase, M. Nishida, Y. Sakata, S. Yamashita (Japan) 12:16 NOVEL INTRANASAL ANTI-CETP VACCINE AGAINST The DEVELOPMENT Of ATHEROSCLEROSIS AND FATTY LIVER DISEASE 64 J. Mas-Oliva, B. Delgado-Coello, K. Méndez-Acevedo (Mexico) 12:30 - 15:00Exhibition & Poster Area Break, Exhibition & Poster Viewing 13:00 - 14:00Exhibition Area Science at a Glance Session I 13:00 - 14:00 Kristall Foyer Poster Walk Session I 46 47 Monday, May 30, 2016 13:00 - 14:30N. Anitschkow Hall 14:00 - 15:00Exhibition Area Industry Symposium: Company Sponsored Session Science at a Glance Session II Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 15:00 - 16:30N. Anitschkow Hall 13:00 - 14:30 EAS-ESC Joint Workshop: Sex Differences in Cardiovascular Diseases K. Landsteiner Hall Industry Symposium: Company Sponsored Session Supported Session. Not included in the CME/CPD Programme. 71 Chair: L. Tokgözoglu (Turkey) 72 15:00 PUBLIC HEALTH PERSPECTIVES ON CARDIOVASCULAR CARE FOR MEN AND WOMEN For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 13:00 - 14:00 Chair: I. Hoefer (Netherlands) 73 K. Kotseva (United Kingdom) C. von Rokitansky Hall 15:22 SEX DIFFERENCES In HEART DISEASE In CLINICAL PRACTICE 15:45 SEX-SPECIFIC BIOMARKERS FOR CARDIOVASCULAR DISEASES EBAC Accredited Session: Nutraceuticals with Lipid Lowering Activity: Who Can Benefit? 74 E. Bossano Prescott (Denmark) 75 B. Nordestgaard (Denmark) This educational programme is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hourof external CME credit(s); Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). 16:07 SEX-SPECIFIC GENOMIC AND PROTEOMIC REGULATION In CARDIOVASCULAR DISEASE 76 G. Kararigas (Germany) EAS have independently organised all matters related to this 60-minute Programme, including content and presenters. We acknowledge financial support, in the form of an educational grant, received from Meda (Rottapharm) in support of the Programme. Chair: P. Kovanen (Finland) 65 Chair: G. Assmann (Germany) 66 13:00 GUIDELINES In PRIMARY PREVENTION 67 E. Farinaro (Italy) 13:15 TO BRIDGE The GAP BETWEEN LIFESTYLE AND PHARMACOLOGICAL TREATMENT: DO WE HAVE AN UNMET NEED? 68 B. Paulweber (Austria) 13:30 PLANT NUTRACEUTICALS FOR The TREATMENT Of HYPERCHOLESTEROLEMIA: The AVAILABLE CLINICAL DATA 69 E. Bruckert (France) 13:45 DISCUSSION AND CONCLUSION 48 70 49 Monday, May 30, 2016 15:00 - 16:30 K. Landsteiner Hall Workshop 1.2: Therapeutic and Diagnostic Targeting of the Arterial Wall Chair: E. Stroes (Netherlands) 77 Chair: A. Tawakol (USA) 78 15:00 NANOMEDICINE AS DIAGNOSTIC TOOL FOR CARDIOVASCULAR DISEASE 79 D. Letourneur (France) A. Tawakol (USA) 15:50 INCREASED ARTERIAL WALL INFLAMMATION In PATIENTS WITH FAMILIAL DYSBETALIPOPROTEINEMIA81 S. Verweij, S. Bernelot Moens, J. Kroon, J. Schnitzler, E. Stroes (Netherlands) Workshop 2.2: Adipose Tissue – Liver Axis Chair: M. Taskinen (Finland) 84 Chair: F. Karpe (United Kingdom) 85 15:00 BIOLOGY Of ADIPOSE TISSUE PHENOTYPE AND ITS LINK TO DISEASE 82 86 F. Karpe (United Kingdom) 87 R.O. Ryan (USA) 15:50 FGF21 LOWERS PLASMA TRIGLYCERIDES BY ACCELERATING LIPOPROTEIn CATABOLISM In WHITE AND BROWN ADIPOSE TISSUES 88 C. Schlein, S. Talukdar, M. Heine, A.W. Fischer, L.M. Krott, S.K. Nilsson, M.B. Brenner, J. Heeren, L. Scheja (Germany) 16:03 OAT2 DEPLETION IMPROVES INSULIn SENSITIVITY AND HEPATIC STEATOSIS D. Agrawal, P. Gunasekar, C. Boosani, V. Swier, M. Radwan, M. Del Core, W. Hunter (USA) 16:16 SPOTTY CALCIFICATION AS A MARKER Of VULNERABLE PLAQUE: NOVEL FINDINGS FROM IN-VIVO STUDY In SURVIVORS Of CARDIAC ARREST AND IN-VITRO STUDY In AUTOPTIC SCD PATIENTS C. von Rokitansky Hall 15:25 APO AV, BEYOND TRIGLYCERIDES 15:25 NON-INVASIVE IMAGING Of ATHEROSCLEROTIC BURDEN AND INFLAMMATION80 16:03 GENE THERAPY REDUCES ANGIOPLASTY INDUCED CORONARY RESTENOSIS In A HIGH CHOLESTEROL SWINE MODEL 15:00 - 16:30 89 P. Parini, C. Pramfalk, O. Ahmed, L. Larsson, F. Karpe, M. Neville, M. Eriksson (Sweden) 16:16 SHORT-TERM COLD EXPOSURE MODULATES HUMAN VLDL AND HDL METABOLISM90 K. Nahon, G. Hoeke, L. Bakker, D. Drettwan, P. Pagel, I. Jazet, J. Berbée, M. Boon, P. Rensen (Netherlands) 83 J. Pu, P. Zhang, G.S. Mintz, X. Ma, B. He (China) 50 51 Monday, May 30, 2016 15:00 - 15:45W. Auerswald Hall 17:00 - 18:30N. Anitschkow Hall Late Breaking: Basic Science Young Investigator Session: Vascular Biology and Inflammation Chair: J. Herz (USA) 91 Chair: R. Zechner (Austria) 92 15:00 FLOW PERTURBATION MEDIATES NEUTROPHIL RECRUITMENT AND POTENTIATES ENDOTHELIAL INJURY VIA TLR2 In MICE. A NOVEL In VIVO APPROACH FOR PROBING The PATHOPHYSIOLOGY Of SUPERFICIAL EROSION93 G. Franck, G. Sausen, T. Mawson, M. Salinas, G. Masson, A. Cole, M. BeltramiMoreira, Y. Chatzizisis, Y. Tesmenitsky, E. Swartz, G. Sukhova, F. Swirski, M. Nahrendorf, E. Aikawa, K. Croce, P. Libby (USA) 15:15 The ATYPICAL CADHERIn FAT1 SUPPRESSES MITOCHONDRIAL RESPIRATION TO LIMIT SMOOTH MUSCLE CELL RESPONSE TO VASCULAR INJURY 100 Chair: L.O. Martinez (France) 101 17:00 IRON ACCELERATES CARDIOVASCULAR DISEASE: The IMPORTANCE Of MAINTAINING IRON BALANCE 102 F. Vinchi, A. Simmelbauer, S. Altamura, B. Galy, M.W. Hentze, M. Muckenthaler (Germany) 94 N. Sibinga, L.L. Cao, D. Riascos-Bernal, P. Chinnasamy, C. Dunaway, M. Pujato, A. Fiser (USA) 15:30 The CORONARY ARTERY DISEASE RISK ASSOCIATED GENE PLPP3/PPAP2B SUPPRESSES ATHEROSCLEROSIS In MICE Chair: K. Öörni (Finland) 17:15 INCREASED APOA-I TRANSCRIPTION BY BET INHIBITOR JQ1(+) ACTS INDEPENDENTLY FROM PPAR-ALPHA ACTIVATION AND IS LINKED TO ER-STRESS INHIBITION 103 S.E. Van der Krieken, H.E. Popeijus, R.P. Mensink, J. Plat (Netherlands) 95 A. Morris, P. Mueller, J. Brandon, L. Yang, S. Smyth (USA) 17:30 PHOSPHATIDYLSERINE IMPROVES ANTI-INFLAMMATORY FUNCTION Of RECONSTITUTED HDL In MACROPHAGES VIA SR-BI-, Akt- AND p38 MAPK-DEPENDENT PATHWAYS 104 M. Darabi, E. Tubeuf, M. Lhomme, I. Guillas-Baudouin, C. Dauteuille, M. Patel, T. Huby, E.L. Gautier, K.A. Rye, P. Lesnik, W. Le Goff, A. Kontush (France) 15:45 - 16:30W. Auerswald Hall Young Investigator Award Session 17:45 CCAAT/ENHANCER BINDING PROTEIn DELTA CONTRIBUTES TO LIPID ACCUMULATION In M1 MACROPHAGES Of BLOOD VESSEL LESIONS 105 H.Y. Lai, L.W. Hsu, P.Y. Liu, J.M. Wang (Taiwan) Chair: P. Kovanen (Finland) 96 Chair: G. Dallinga-Thie (Netherlands) 97 15:45 GRP94 REGULATES CIRCULATING CHOLESTEROL LEVELS THROUGH BLOCKADE Of PCSK9-INDUCED LDLR DEGRADATION 98 S. Poirier (Canada) 16:05 ASSOCIATION BETWEEN FAMILIAL HYPERCHOLESTEROLEMIA AND PREVALENCE Of TYPE 2 DIABETES MELLITUS 99 J. Besseling (Netherlands) 18:00 INHIBITION Of The CHOLESTEROL SYNTHESIS PATHWAY PREVENTS TRAINED INNATE IMMUNITY 106 S. Bekkering, S. Bernelot Moens, S. Verweij, J. Roeters van Lennep, J. Van Tuijl, L. Joosten, E. Stroes, M. Netea, N. Riksen (Netherlands) 18:15 SELECTIVE DONOR ENDOTHELIAL HEPARAN SULFATE MODIFYING ENZYME NDST1 DELETION SIGNIFICANTLY BLOCKS REJECTION AFTER RENAL TRANSPLANT 107 S. Ambadapadi, H. Chen, D. Wakefield, S. Morshed, W. Clapp, A. Lucas (USA) 16:30 - 17:00Exhibition & Poster Area Coffee Break, Exhibition & Poster Viewing 17:00 - 18:00 Kristall Foyer Poster Walk Session II 52 53 Monday, May 30, 2016 17:00 - 18:30 K. Landsteiner Hall Young Investigator Session: Lipids and Lipoprotein Metabolism 17:00 - 18:30 C. von Rokitansky Hall Young Investigator Session: Clinical Epidemiology and Pharmacology Chair: L. Scheja (Germany) 108 Chair: K. Kotseva (United Kingdom) 116 Chair: A. Ritsch (Austria) 109 Chair: P.D. Reaven (USA) 117 17:00 PARAOXONASE 1 (PON1) MAINTAINS CELLULAR CHOLESTEROL HOMEOSTASIS VIA The REGULATION Of CHOLESTEROL EFFLUX 110 S. Ikhlef, H. Berrougui, A. Khalil (Canada) 17:15 A UBIQUITOUS TRANSCRIPTION FACTOR INFLUENCES DIET-INDUCED THERMOGENESIS AND SENSITIZES BAt TO NORADRENERGIC STIMULI IMPROVING CARDIOMETABOLIC HEALTH 111 112 M. SHARMA, G. Redpath, S. McCormick (New Zealand) 17:45 PLASMA CETP IS DERIVED FROM HEPATIC KUPFFER CELLS RATHER THAN ADIPOSE TISSUE 113 114 119 B. Arsenault, F. Tabet, W. Bao, F. Petrides, G.K. Hovingh, S.M. Boekholdt, D. DeMicco, K.A. Rye, D. Waters, J. Kastelein, P. Barter, G. Lambert (Canada) 17:30 CLINICAL CHARACTERISTICS AND LONG-TERM CLINICAL OUTCOMES Of PATIENTS WITH TYPICAL RESTING CHEST PAIn ACCORDING TO The TYPES Of VASOMOTOR RESPONSE TO AN ACETYLCHOLINE PROVOCATION TEST 120 17:45 RESPONSE TO TREATMENT AND OCCURRENCE Of CARDIOVASCULAR (CV) COMPLICATIONS In PATIENTS WITH AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA (ARH): A RETROSPECTIVE ANALYSIS 121 L. D'Erasmo, I. Minicocci, L. Masana, J. Roeters van Lennep, M. Harada-Shiba, S. Muntoni, P. Pintus, S. Bertolini, C. Sirtori, L. Calabresi, C. Pavanello, M. Averna, A.B. Cefalù, D. Noto, A. Pacifico, G. Pes, R. Fellin, E. Manzato, S. Zambon, M. Arca (Italy) E. Garcia-Vaz, A. Mc Neilly, J. Gallagher, R. Mc Crimmon, F. Khan, M.F. Gomez (Sweden) 18:15 OXYSTEROLS, 24S-HYDROXYCHOLESTEROL AND 27-HYDROXYCHOLESTEROL, In SUBJECTS WITH GENETIC HYPERCHOLESTEROLEMIA NEGATIVE FOR LDLR/APOB/PCSK9/APOE MUTATIONS. ASSOCIATION WITH LIPIDS AND CAROTID ATHEROSCLEROSIS 17:15 IMPACT Of DIABETES, INSULIn RESISTANCE AND CETP INHIBITION ON CIRCULATING PCSK9 LEVELS In PATIENTS At HIGH CARDIOVASCULAR RISK: The ILLUMINATE STUDY E.M. Lee, H.S. Seo, M.H. Choi, H.K. Kim, S.Y. Lee, N.H. Kim, D.O. Kang, C.U. Choi, J.W. Kim, E.J. Kim, S.W. Rha, C.G. Park, D.J. Oh (Republic of Korea) L. Blauw, R. De Mutsert, Y. Wang, H. Lamb, A. De Roos, F. Rosendaal, W. Jukema, S. Van der Tuin, S. Rensen, R. Shiri-Sverdlov, B. Atanasovska, J. Fu, W. Buurman, J.W. Greve, M. Hofker, K. Willems van Dijk, P. Rensen (Netherlands) 18:00 In VIVO INHIBITION Of NUCLEAR FACTOR Of ACTIVATED T CELLS (NFAT) RESTORES MICROVASCULAR ENDOTHELIAL FUNCTION In DIABETIC MICE 118 N. Wong, E. Kulikowski, S. Wasiak, D. Gilham, C. Calosing, T. Laura, C. Halliday, J. Johansson, M. Sweeney (Canada) P.P. Laurila, J. Soronen, S. Kooijman, M. Boon, M.R. Taskinen, V. Olkkonen, S. Ripatti, P. Kovanen, P. Rensen, M. Jauhiainen (Finland) 17:30 CALCIUM DEPENDENT ENDOCYTOSIS AND RECYCLING Of LIPOPROTEIN(A) In HEPG2 CELLS 17:00 APABETALONE (RVX-208) DECREASES ATHEROGENIC, THROMBOTIC AND INFLAMMATORY MEDIATORS In VITRO AND In PLASMA Of PATIENTS WITH CARDIOVASCULAR DISEASE (CVD). 115 L. Baila-Rueda, A. Cenarro, I. Lamiquiz-Moneo, R. Mateo-Gallego, A.M. Bea-Sanz, S. Perez-Calahorra, V. Marco-Benedi, F. Civeira (Spain) 18:00 ASSOCIATION Of PERIPHERAL BLOOD MONONUCLEAR CELLS ADENYLATE CYCLASE-ASSOCIATED PROTEIn 1 mRNA WITH CORONARY ARTERY DISEASE 122 M. Sopic, J. Joksić, V. Spasojević Kalimanovska, D. Kalminaovska Oštrić, K. Anđelković, Z. Jelić Ivanović (Serbia) 18:15 FILAGGRIn MUTATIONS AS RISK FACTORS FOR ISCHEMIC STROKE In The GENERAL POPULATION 123 A. Varbo, B.G. Nordestgaard, M. Benn (Denmark) 54 55 17:00 - 18:30W. Auerswald Hall Oral Communication Session: Vascular Biology Chair: L. Yvant-Charvet (France) 124 Chair: K. Ley (USA) 125 17:00 SELECTIVE HDL-RAISING GENE TRANSFER COUNTERACTS The DEVELOPMENT Of PRESSURE OVERLOAD-INDUCED CARDIOMYOPATHY In MICE 126 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria R. Amin, I. Muthuramu, F. Jacobs, B. De Geest (Belgium) 17:15 BONE MARROW-SPECIFIC SIRT6 DELETION INCREASES ATHEROGENESIS BY INCREASING MACROPHAGE SCAVENGER RECEPTOR 1 127 T. Arsiwala, L. J. van Tits, M. Miranda, K. Nussbaum, J. Weber, S. Stivala, J. H. Beer, M. Greter, B. Becher, M. O. Hottiger, R. Mostoslavsky, J. Auwerx, T. F. Lüscher, C. M. Matter (Switzerland) 17:30 T CELL-SPECIFIC CD40L CONTRIBUTES TO ATHEROSCLEROSIS 128 C. Bürger, H. Winkels, C. Spitz, S. Meiler, S. Reim, C. Weber, E. Lutgens, N. Gerdes (Germany) 17:45 STRUCTURAL REMODELING AND GLUCOSE METABOLISM IMPAIRMENT At EARLY ATHEROSCLEROSIS: IN-SITU AORTA ALTERATIONS AND PLASMA TRANSLATION.129 M. Martin-Lorenzo, L. Gonzalez-Calero, A.S. Maroto, P.J. Martinez, A. Heredero, G. Aldamiz-Echevarria, F. Vivanco, G. Alvarez-Llamas (Spain) 18:00 LIVER-SPECIFIC ABLATION Of HNF-4α In MICE IS ASSOCIATED WITH CHANGES In PLASMA LIPOPROTEIn PROFILES AND The EXPRESSION Of GENES INVOLVED In LIPOPROTEIn METABOLISM 130 E. Thymiakou, D. Kardassis (Greece) 18:15 HEPATOCYTE-SPECIFIC PPAP2B ABLATION INCREASES PLASMA LEVELS Of SEVERAL MINOR PRO-ATHEROGENIC LIPID SPECIES AND WORSENS ATHEROSCLEROSIS In APOE-/- MICE 131 M. Busnelli, S. Manzini, M. Hilvo, C. Parolini, G.S. Ganzetti, F. Dellera, K. Ekroos, M. Jänis, C.R. Sirtori, R. Laaksonen, G. Chiesa (Italy) 18:40 - 19:40N. Anitschkow Hall Plenary: Keynote Lecture Chair: A. Catapano (Italy) 132 Chair: W.J. Schneider (Austria) 133 18:40 HOW GENES CONTROL CHOLESTEROL M.S. Brown (USA) 56 134 e m m a r g o r P c fi i Scient ay 31, 2016 Tuesday, M www.eas2016.kenes.com Tuesday, May 31, 2016 Tuesday, May 31, 2016 8:30 - 10:30N. Anitschkow Hall Plenary: Lipid Biology, New Insights 8:30 Chair: G. Kostner (Austria) 135 Chair: O. Wiklund (Sweden) 136 PATHOPHYSIOLOGY Of INTERCELLULAR AND INTRAVASCULAR LIPOLYSIS 137 R. Zechner (Austria) 9:00 ADIPOSE TISSUE BROWNING AND METABOLIC HEALTH 138 J. Heeren (Germany) 9:30 NUCLEAR RECEPTORS In LIPID METABOLISM 139 D. Mangelsdorf (USA) 10:00 ANGIOGENESIS AND ENDOTHELIAL CELL DYSFUNCTION In ATHEROSCLEROSIS: A NOVEL TARGET FOR TREATMENT 140 P. Carmeliet (Belgium) 10:30 - 11:00Exhibition & Poster Areater Area Coffee Break, Exhibition & Poster Viewing 59 Tuesday, May 31, 2016 11:00 - 12:30N. Anitschkow Hall 11:00 - 12:30 Workshop 1.3: Cellular Stress Response in Atherosclerosis Workshop 2.3: Gut - Liver Axis K. Landsteiner Hall Chair: G.R.Y. De Meyer (Belgium) 198 Chair: A. Moschetta (Italy) 205 Chair: R. Prassl (Austria) 199 Chair: D. Kardassis (Greece) 206 11:00 MICTOPARTICLES In ATHEROSCLEROSIS 200 C.M. Boulanger (France) 11:25 ROLE Of AUTOPHAGY In VASCULAR DISORDERS 201 202 S. Lehti, I. Belevich, S.D. Nguyen, P. Lindsberg, E. Jokitalo, P.T. Kovanen, K. Oörni (Finland) 11:50 A MARCH6 AND IDOL E3 UBIQUITIn LIGASE CIRCUIT UNCOUPLES CHOLESTEROL SYNTHESIS FROM LIPOPROTEIn UPTAKE In HEPATOCYTES 209 A. Loregger, E. Cook, J. Nelson, M. Moeton, L. Sharpe, S. Engberg, M. Karimova, G. Lambert, N. Zelcer (Netherlands) 203 E. Ehrenborg, P. Gustafsson, O. Werngren, M. Pedrelli, P. Parini, J. Magné (Sweden) 12:16 EXTRACELLULAR LIPID PARTICLES ACCUMULATING In HUMAN CAROTID ARTERY INTIMA INDUCE STERILE INFLAMMATION In MACROPHAGES 208 A. Moschetta (Italy) D. De Gonzalo Calvo, A. Cenarro, F. Civeira, V. Llorente-Cortés (Spain) 12:03 A FUNCTIONAL GENETIC VARIANT In The LIPID DROPLET-ASSOCIATED PROTEIn PERILIPIn 2 (PLIN2) AFFECTS CHOLESTEROL CONTENT AND AUTOPHAGY In HUMAN PRIMARY MACROPHAGES TREATED WITH OXLDL 207 M.J. Brown (USA) 11:25 INTESTINAL NUCLEAR RECEPTORS In LIPID REGULATION G.R.Y. De Meyer (Belgium) 11:50 HYPERCHOLESTEROLEMIA ALTERS The microRNA PROFILE Of VASCULAR SMOOTH MUSCLE CELL-DERIVED MICROPARTICLES 11:00 The GUT MICROBIOME ENDOCRINE ORGAN: BACTERIALLY SIGNALS DRIVING CARDIO-METABOLIC DISEASES 12:03 BUTYRATE VIA The GUT-BRAIn CIRCUIT REDUCES APPETITE AND ACTIVATES BROWN ADIPOSE TISSUE 210 Y. Wang, L. Zhuang, C. Yi, C.K. Chuang, S. Kooijman, K. Willems van Dijk, A.K. Groen, P.C.N. Rensen 204 12:16 NON-ALCOHOLIC FATTY LIVER DISEASE AS A CAUSE Of ISCHEMIC HEART DISEASE: A MENDELIAN RANDOMIZATION STUDY AND META-ANALYSIS Of 170,998 INDIVIDUALS 211 B. Lauridsen, S. Stender, T. Kristensen, K. Kofoed, B. Nordestgaard, A. Tybjærg-Hansen (Denmark) 60 61 Tuesday, May 31, 2016 11:00 - 12:30 C. von Rokitansky Hall Workshop: ICCR-EAS Joint Session: Management of Cardiometabolic Risk; Where Do We Stand? Workshop 3.2: Vascular Aging and Atherothrombosis Chair: J.P. Després (Canada) 212 Chair: J. Chapman (France) 213 11:00 MANAGEMENT Of SUBJECTS At HIGH CARDIOMETABOLIC RISK - WHERE DO WE FALL? 214 J.P. Després (Canada) 11:22 DOES The HEALTHY METABOLICALLY OBESE PHENOTYPE EXIST? 215 216 V. Malik (USA) 12:07 NAFLD - The NOVEL TREAt FOR VASCULAR DISEASE M. Taskinen (Finland) Chair: C. Gaetano (Germany) 218 Chair: B. Föger (Austria) 219 11:00 VASCULAR PROGENITOR CELLS, LYMPHATICS, ANGIOGENESIS AND ATHEROSCLEROSIS220 A. Kari (Finland) 11:25 SIRTUINS In CARDIOVASCULAR DISEASE L. Van Gaal (Belgium) 11:45 TRANSLATING NUTRITIONAL SCIENCE INTO CLINICAL PRACTICE 11:00 - 12:30W. Auerswald Hall 217 221 C. Gaetano (Germany) 11:50 PENTRAXIn 3 DEFICIENCY IS ASSOCIATED WITH INCREASED ARTERIAL THROMBOSIS In ANIMAL MODELS 222 F. Bonacina, S. Barbieri, L. Cutuli, P. Amadio, A. Doni, M. Sironi, S. Tartari, B. Bottazzi, C. Garlanda, E. Tremoli, A. Mantovani, A.L. Catapano, G.D. Norata (Italy) 12:03 HDL MODULATES CARDIAC GLUCOSE METABOLISM AND INFLAMMATION AND IMPROVES CARDIAC FUNCTION AFTER MYOCARDIAL ISCHEMIAREPERFUSION INJURY 223 B. Kingwell, S. Heywood, A. Richart, D. Henstridge, K. Alt, H. Kiriazis, A. Carey, H. Kammoun, H. Begum, L. Delbridge, P. Meikle, C. Hagemeyer, M. Febbraio, X.J. Du, A. Siebel (Australia) 12:16 DIET-INDUCED OBESITY REQUIRES SIGNALLING THROUGH TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 1 (TRAF-1) In ADIPOCYTES224 D. Wolf, N. Anto Michel, I. Hilgendorf, Bode, A. Zirlik (Germany) 12:30 - 15:00Exhibition & Poster Area Break, Exhibition & Poster Viewing 13:00 - 14:00Exhibition Area Science at a Glance Session III 13:00 - 14:00 Kristall Foyer Poster Walk Session III 62 63 Tuesday, May 31, 2016 13:00 - 14:30 K. Landsteiner Hall Industry Symposium: Company Sponsored Session EBAC Accredited Session: Lysosomal Acid Lipase Deficiency Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 13:00 - 14:00 C. von Rokitansky Hall EBAC Accredited Session: Low HDL High Triglyceride, Diabetic Dyslipidaemia This educational programme is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hourof external CME credit(s); Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). EAS have independently organised all matters related to this 60-minute Programme, including content and presenters. We acknowledge financial support, in the form of an educational grant, received from Mylan in support of the Programme. Chair: O. Wiklund (Sweden) 13:00 DIABETIC DYSLIPIDEMIA 225 226 A. Zambon (Italy) 13:20 TRIGLYCERIDE, REMNANTS AND ATHEROSCLEROSIS This educational programme is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hourof external CME credit(s); Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). EAS have independently organised all matters related to this 60-minute Programme, including content and presenters. We acknowledge financial support, in the form of an educational grant, received from Alexion in support of the Programme. Chair: E. Bruckert (France) 229 Chair: P. Kovanen (Finland) 230 13:00 LIPID METABOLISM ABNORMALITIES In GENERAL WITH DIFFERENTIAL DIAGNOSIS INCLUDING ALSO LAL-D 231 T. Stulnig (Austria) 13:20 LIPID METABOLISM ABNORNALITIES In LAL-D AS A LYSOSOMAL STORAGE DISEASE WITH A FOCUS ON SPECIFIC SIGNS AND SYMPTOMS 232 M. Averna (Italy) 13:40 CONCLUSION AND DISCUSSION 233 14:00 - 15:00Exhibition Area 227 Science at a Glance Session IV 228 14:00 - 14:45N. Anitschkow Hall B. Nordestgaard (Denmark) 13:40 CONCLUSION AND DISCUSSION 13:00 - 14:00W. Auerswald Hall Industry Symposium: Special Lecture Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 14:10 - 14:55 C. von Rokitansky Hall Industry Symposium: Company Sponsored Session Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. 64 65 Tuesday, May 31, 2016 14:05 - 14:50W. Auerswald Hall 15:00 - 16:30 Industry Symposium: Meet the Expert Late Breaking: Clinical Science Supported Session. Not included in the CME/CPD Programme. For programme details please refer to the Recognition, Acknowledgements & Commercial Support section in the final Programme. Workshop 3.3: Genetics in Risk Factor Prevention and Treatment Chair: G. Utermann (Austria) 234 Chair: S. Ripatti (Finland) 235 236 S. Ripatti (Finland) 15:20 LOSS-OF-FUNCTION MUTATIONS In APOC3, REMNANT CHOLESTEROL, LDL CHOLESTEROL, AND RISK Of ISCHEMIC VASCULAR DISEASE 237 A.B. Jørgensen, R. Frikke-Schmidt, B. Nordestgaard, A. Tybjaerg-Hansen (Denmark) 15:34 LEUKOCYTE TELOMERE LENGTH, GENETICALLY DETERMINED, IS CAUSALLY ASSOCIATED WITH The PROGRESSION Of CAROTID INTIMAMEDIA THICKNESS AND INCIDENCE Of CARDIOVASCULAR EVENTS 238 239 240 244 D. Gaudet, S. Saheb, E. Bruckert, J. De Graaf, G. Langslet, J.C. Tardif, S. Bergheanu, A. Steinberg, Y.J. Choi, R. Martin, C. McWherter, J. Kastelein, P. Boudes (USA) 15:15 AFFITOPE-BASED ANTI-PCSK9 (PROPROTEIn CONVERTASE SUBTILISIN/ KEXIn TYPE 9) VACCINE (AT04A) REDUCES ATHEROSCLEROSIS In APOE*3LEIDEN.CETP MICE 245 G. Galabova, C. Juno, J.W.A. Van der Hoorn, E.J. Pieterman, M. Pouwer, C. Landlinger, J.W. Jukema, H.M.G. Princen, G. Staffler (Austria) 15:30 TREATMENT ADHERENCE TO The PROPROTEIn CONVERTASE SUBTILISIN/ KEXIn TYPE 9 INHIBITOR ALIROCUMAB In SIX ODYSSEY PHASE 3 CLINICAL STUDIES WITH TREATMENT DURATION Of 52 - 104 WEEKS 246 M. Farnier, H.M. Colhoun, W.J. Sasiela, J. Edelberg, G. Asset, J.G. Robinson (France) 247 D. Gaudet, D.A. Gipe, E. Khoury, R. Pordy, W. Sasiela, K.C. Chan 248 J. Sun, J. Liu, N. Balu, D. Hippe, K. William, A. Wang, G. Canton, T. Hatsukami, C. Yuan (USA) 16:15 MORTALITY In RELATION TO GLYCAEMIC STATUS In PATIENTS WITH PERIPHERAL ARTERIAL DISEASE 249 I.D. Hjellestad, E. Søfteland, R.M. Nilsen, E.S. Husebye, T. Jonung (Norway) I. Brænne, C. Willenborg, B. Reiz, L. Zeng, V. Tragante do Ó, T. Meitinger, N.J. Samani, T. Kessler, F.W. Asselbergs, J. Erdmann, H. Schunkert (Germany) 16:16 INVESTIGATION Of MULTIPLE DYSLIPIDEMIAS In A LARGE AUSTRIAN PEDIGREE BY GENETIC RISK SCORES AND EXOME SEQUENCING 243 16:00 DYNAMIC CHANGES In MR SIGNALS Of INTRAPLAGUE HEMORRHAGE ARE STRONGLY CORRELATED WITH PLAQUE PROGRESSION: A SERIAL IMAGING STUDY ON CAROTID ATHEROSCLEROSIS I. Khurana, A. El-Osta (Australia) 16:02 PLEIOTROPIC MOLECULAR TARGETS Of COXIBS REVEALS NOVEL GENOMIC LOCI CONFERRING CORONARY ARTERY DISEASE RISK 242 Chair: M. Vrablik (Czech Republic) 15:45 SAFETY AND EFFICACY Of EVINACUMAB, A MONOCLONAL ANTIBODY TO ANGPTL3, In PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: A SINGLE-ARM, OPEN-LABEL, PROOF-OFCONCEPT STUDY A. Baragetti, J. Palmen, K. Garlaschelli, L. Grigore, S. Humphries, A.L. Catapano, P.J. Talmud, N. Giuseppe Danilo (Italy) 15:48 DEEP SEQUENCING IDENTIFIES DNA METHYLATION DEPENDENT GENES IMPLICATED In DIABETIC COMPLICATIONS Chair: P. Moulin (France) 15:00 A PILOT STUDY Of MBX-8025 In The TREATMENT Of HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HoFH) 15:00 - 16:30N. Anitschkow Hall 15:00 GENETIC DISCOVERIES FOR LIPID GENETIC TRAITS. LESSON LEARNED FROM FAMILIES AND The GENERAL POPULATION K. Landsteiner Hall 241 E. Nikkola, A. Ko, R.M. Cantor, R. Muxel, N. Matikainen, S. Söderlund, M.M. Motazacker, J.A. Kuivenhoven, J. Boren, F. Kronenberg, W. Schneider, A. Palotie, M. Laakso, M.R. Taskinen, P. Pajukanta (USA) 66 67 Tuesday, May 31, 2016 15:00 - 16:30 C. von Rokitansky Hall EAS Initiatives Update Session (open to all) 250 Chair: O. Wiklund (Sweden) 251 252 253 17:00 - 18:00 K.K. Ray (United Kingdom) 15:30 CONSENSUS ACTIVITIES HIGHLIGHT- CONSENSUS ON FASTING/ NONFASTING LIPID ANALYSES (WITH EFLM) 16:30 - 17:00Exhibition & Poster Area Coffee Break, Exhibition & Poster Viewing A. Catapano (Italy) 15:15 FHSC UPDATE C. von Rokitansky Hall EAS General Assembly (Members Only) Chair: A. Catapano (Italy) 15:00 WELCOME AND OVERVIEW Of EAS ACTIVITIES 16:30 - 16:50 254 Kristall Foyer Poster Walk Session IV B. Nordestgaard (Denmark) 15:45 EDUCATIONAL ACTIVITIES HIGHLIGHT- ADVANCED COURSES & EAS ACADEMY ACCREDITED PROGRAMMES 255 L. Tokgözoglu (Turkey) 15:55 OTHER ACTIVITIES: GUIDELINES & CONSENSUS UPDATE Workshop 3.5: Epigenetics and Gene Regulation 256 A. Catapano (Italy) 16:05 OTHER ACTIVITIES: JOURNAL 257 258 A. Catapano (Italy) Advanced Clinical Seminar: Economics and Guidelines/ Technology of the Future 259 Chair: G. Dallinga-Thie (Netherlands) 260 261 G. Corrao (Italy) 262 G. Kostner (Austria) 68 17:00 The EMERGING ROLE Of microRNAs In CARDIOVASCULAR DISEASE 17:25 IDENTIFICATION Of HISTONE DEACETYLASE 3 AS A MOLECULAR BRAKE Of WHITE ADIPOSE TISSUE BROWNING 17:38 HYPERCHOLESTEROLEMIA TRANSFORMS HIGH-DENSITY LIPOPROTEINSMEDIATED TRNA-DERIVED SMALL RNA INTERCELLULAR COMMUNICATION 17:51 QUAKING POST-TRANSCRIPTIONALLY PROMOTES DIFFERENTIATION Of MONOCYTES INTO PRO-ATHEROGENIC MACROPHAGES BY CONTROLING PRE-MRNA SPLICING AND GENE EXPRESSION 266 267 268 263 269 R.G. De Bruin, L. Shiue, J. Prins, A. Djaramshi, H. De Boer, W.S. Fagg, J. Van Gils, J. Duijs, C. Van Kooten, J.W. Jukema, H. Van Esch, T.J. Rabelink, H. Kazan, E.A.L. Biessen, M. Ares Jr., A.J. Van Zonneveld, E. Van der Veer (Netherlands) 18:09 INNATE IMMUNE CELL ACTIVATION In SYMPTOMATIC AND ASYMPTOMATIC ATHEROSCLEROSIS In HUMANS In VIVO N. Sanjana (USA) 16:00 WHAt DID WE LEARN FROM Lp(a)? SUMMARY Of The SATELLITE MEETING 265 R. Allen, D. Michell, W. Zhu, S. Zhao, Q. Sheng, L. MacRae, K. Vickers (USA) Chair: M. Banach (Poland) 15:30 CrisprCas9 TECHNOLOGY AS A NEW STRATEGY FOR TARGET DISCOVERY 264 Chair: A. El-Osta (Australia) M. Crestani, A. Ferrari, E. Fiorino, R. Long, N. Mitro, G. Cermenati, A. Mai, D. Caruso, E. De Fabiani, S.W. Hiebert (Italy) 15:00 - 16:30W. Auerswald Hall 15:00 PHARMACO-ECONOMICS - HOW TO EXPLORE IT Chair: L. Maegdefessel (Sweden) L. Maegdefessel (Sweden) A. von Eckardstein (Switzerland) 16:15Q&A 17:00 - 18:30N. Anitschkow Hall 270 S. Bekkering, I. Van den Munckhof, T. Nielen, J. Rutten, J. De Graaf, L. Joosten, M. Netea, M. Gomes, N. Riksen (Netherlands) 69 Tuesday, May 31, 2016 17:00 - 18:30 K. Landsteiner Hall Oral Communication Session: Imaging, Biomarkers and Clinical Epidemiology 17:00 - 18:30 C. von Rokitansky Hall Oral Communication Session: Intracellular Lipid Metabolism Chair: D. Letourneur (France) 271 Chair: D. Kratky (Austria) 279 Chair: B. Paulweber (Austria) 272 Chair: J. Heeren (Germany) 280 17:00 ULTRA-SMALL POSITIVE AND NEGATIVE DUAL CONTRAST IRON OXIDE NANOPARTICLES FOR MOLECULAR IMAGING Of CARDIOVASCULAR DISEASE 273 H. Ta, Z. Li, K. Peter, C. Hagemeyer, A. Whittaker (Australia) 17:15 COMPUTED TOMOGRAPHY ANGIOGRAPHY DERIVED COMPARED TO INVASIVE FRACTIONAL FLOW RESERVE ASSESSMENT. A META-ANALYSIS. 274 275 17:45 In TYPE 2 DIABETES MELLITUS The GLP-1 EFFECTS ON PLATELETS ARE IMPAIRED276 277 L.R. Lopez, T. Bottiglieri, A. Vasudevan, C. Swift, R. Schiffmann, P.A. McCullough (USA) M. Schneider, M. Mieth, S. Titze, F. Kronenberg, Y. Li, R. Maas, K.U. Eckardt (Germany) 17:30 CONVERGENT SIGNALING PATHWAYS CONTROLLED BY LRP1 CYTOPLASMIC AND EXTRACELLULAR DOMAINS LIMIT CELLULAR CHOLESTEROL ACCUMULATION 282 284 N. Vujic, S. Schlager, T.O. Eichmann, M. Goeritzer, C.T. MadreiterSokolowski, S. Schauer, A. Lass, R. Zimmermann, G. Hoefler, W.F. Graier, B. Radovic, D. Kratky (Austria) 18:00 LACK Of ADIPOSE TISSUE LIPOLYSIS PROTECTS AGAINST PRESSURE OVERLOAD-INDUCED HEART FAILURE 278 283 P. Boucher, Z. El Asmar, J. Terrand, M. Jenty, L. Host, M. Mlih, A. Zerr, H. Justiniano, R. Matz L., C. Boudier, E. Scholler, J.M. Garnier, D. Bertaccini, D. Thiersé, C. Schaeffer, V.D. Alain, J. Herz (France) 17:45 MONOGLYCERIDE LIPASE REGULATES ENDOCANNABINOID TONE AND ATHEROSCLEROTIC PLAQUE STRUCTURE In APOLIPOPROTEIn E-DEFICIENT MICE C. Barale, C. Frascaroli, F. Cavalot, A. Guerrasio, I. Russo (Italy) 18:15 ASYMMETRIC DIMETHLYARGININE DIRECTLY PROMOTES CHRONIC KIDNEY DISEASE PROGRESSION: EVIDENCE FROM A MENDELIAN RANDOMIZATION APPROACH In The GCKD STUDY 17:15 α/β HYDROLASE DOMAIN-CONTAINING 6 (ABHD6) DEGRADES The LATE ENDOSOMAL/LYSOSOMAL LIPID BIS(MONOACYLGLYCERO)PHOSPHATE R. Zimmermann (Austria) R. Laaksonen, K. Ekroos, M. Sysi-Aho, T. Vihervaara, D. Kauhanen, M. Hilvo, R. Hurme, E. Ringdal Pedersen, G. Tell, O. Nygård (Finland) 18:00 INCREASED F2-ISOPROSTANE OXIDATIVE STRESS In CORONARY ARTERY DISEASE (CAD) PATIENTS WITH POOR ASPIRIN-INDUCED THROMBOXANE B2 INHIBITION 281 L.O. Martinez, G. Cardouat, S. Fried, S. Najib (France) S. Baumann, M. Renker, S. Hetjens, T. Becher, D. Loßnitzer, I. Akin, M. Borggrefe, U.J. Schoepf (Germany) 17:30 PLASMA CERAMIDES IDENTIFY RESIDUAL CARDIOVASCULAR RISK In STATIn TREATED CORONARY ARTERY DISEASE PATIENTS 17:00 AN UNEXPECTED ROLE Of AUTOPHAGY In TARGETING FUNCTIONAL MITOCHONDRIAL ATP SYNTHASE TO The PLASMA MEMBRANE: ITS ROLE In HDL ENDOCYTOSIS 285 A. Foryst-Ludwig, J. Salatzki, S. Brix, Z. Ban, J. Grune, R. Klopfleisch, M. Rothe, E. Kershaw, U. Kintscher (Germany) 18:15 A LOSS-OF-FUNCTION VARIANT In OSBPL1A PREDISPOSES TO LOW PLASMA HDL CHOLESTEROL LEVELS AND IMPAIRED CHOLESTEROL EFFLUX CAPACITY 286 J. Van Capelleveen, J. Pirhonen, M.M. Motazacker, M. Weber-Boyvat, M. Jauhiainen, G.K. Hovingh, G.M. Dallinga-Thie, V. Olkkonen (Netherlands) 70 71 17:00 - 18:30W. Auerswald Hall Young Investigator Session: Novel Pathways in Atherosclerosis Chair: J.A. Kuivenhoven (Netherlands) 287 Chair: R.O. Ryan (USA) 288 17:00 REDUCING AMYLOID PROCESSING PREVENTS DIABETES INDUCED VASCULAR DYSFUNCTION. 84 EAS CONGRESS th 289 May 29 - June 1, 2016 Innsbruck, Austria P. Meakin, F. Khan, M. Ashford (United Kingdom) 17:15 A LIPID METABOLITE PROFILE In ATHEROSCLEROTIC PLAQUES ASSOCIATED WITH INCREASED INFLAMMATION AND CARDIOVASCULAR RISK 290 L. Tomas, H. Björkbacka, A. Edsfeldt, A. Danielsson, M. Wigren, H. Grufman, A. Persson, C. Prehn, J. Adamski, J. Nilsson, I. Gonçalves (Sweden) 17:30 A COMPLEX ATHEROSCLEROTIC PHENOTYPE Of MIF GENE-DEFICIENT MICE In AN ATHEROGENIC APOE-/- BACKGROUND UNCOVERS A NOVEL CONNECTION BETWEEN MIF AND B CELLS 291 C. Schmitz, E. Straußfeld, O. El Bounkari, H. Noels, J. Bernhagen (Germany) 17:45 MARKERS Of VULNERABLE PLAQUES In NON-HUMAN PRIMATES UNDER ATHEROGENIC DIET 292 V. Di Cataldo, J. Piraquive Agudelo, A. Geloen, M. Verset, A. Paturet, A. Serusclat, F. Lamberton, D. Ibarolla, F. Lavenne, D. Le Bars, H. Contamin, E. Canet-Soulas (France) 18:00 The ROLE Of INFLAMMATION In The ASSOCIATION BETWEEN ADIPOSITY AND SUBCLINICAL ATHEROSCLEROSIS 293 T. Christen, S. Trompet, K.B. Gast, P.C.N. Rensen, J.A.P. Willems van Dijk, H.J. Lamb, A. De Roos, J.W. Jukema, F.R. Rosendaal, S. Le Cessie, R. De Mutsert (Netherlands) 18:15 The RELATIONSHIP Of NETRIN- 1 EXPRESSION WITH MACROPHAGE INFILTRATION AND POLARIZATION In HUMAN EPICARDIAL ADIPOSE TISSUE AND SEVERITY Of CORONARY ARTERY DISEASE 294 K.M. Gurses, F. Ozmen, D. Kocyigit, N. Yersal, E. Bilgic, E. Kaya, C. Kopru, T. Soyal, S. Doganci, L. Tokgozoglu, P. Korkusuz (Turkey) e m m a r g o r P c fi i Scient y, June 1, 2016 Wednesda 72 www.eas2016.kenes.com Wednesday, June 1, 2016 Wednesday, June 1, 2016 8:30 - 10:30 K. Landsteiner Hall Plenary: Future Therapeutic Challenges 8:30 Chair: F. Kronenberg (Austria) 295 Chair: L. Tokgözoglu (Turkey) 296 In INTEGRATIVE OMICS APPROACH In HUMAN DISEASE RESEARCH 297 K. Suhre (Qatar) 9:00 DRUGS FOR METABOLIC DISORDERS AND OBESITY 298 M. Tschöp (Germany) 9:30 The USE Of NOVEL THERAPIES In ATHEROSCLEROSIS: FROM ANTIBODIES TO NANOTECHNOLOGY 299 E. Stroes (Netherlands) 10:00 LESSONS LEARNED FROM EMERGING THERAPIES FOR SEVERE HYPERTRIGLYCERIDEMIA300 D. Gaudet (Canada) 10:30 - 11:00Exhibition & Poster Area Coffee Break, Exhibition & Poster Viewing 75 Wednesday, June 1, 2016 11:00 - 12:30 K. Landsteiner Hall Workshop 1.4: Inflammation, Immunity and Atherosclerosis C. von Rokitansky Hall Workshop 3.4: Biology of CVD Risk Chair: G.D. Norata (Italy) 301 Chair: H. Colhoun (United Kingdom) 308 Chair: E. Lutgens (Netherlands) 302 Chair: F. Kronenberg (Austria) 309 11:00 TARGETING The ADAPTIVE IMMUNE SYSTEM: A NEW STRATEGY In ATHEROSCLEROSIS303 E. Lutgens (Netherlands) 11:25 CHOLESTEROL, INFLAMMATION AND IMMUNITY 11:50 CD27 CO-STIMULATION FOSTERS REGULATORY T CELL SURVIVAL AND AMELIORATED PROGRESSION Of ATHEROSCLEROSIS. 305 306 D. Tsiantoulas, I. Bot, M. Kiss, B. Bartolini-Gritti, L. Göderle, M. OzsvarKozma, T. Perkmann, K. Hartvigsen, A. Bergthaler, D.H. Conrad, J. Kuiper, Z. Mallat, H. Jumaa, C.J. Binder (Austria) 311 G. Pasterkamp (Netherlands) 312 P. Willeit, X. Yin, D. Kaudewitz, P. Skroblin, A. Zampetaki, A.R. Moschen, C.M. Ramirez, L. Goedeke, N. Rotllan, E. Bonora, A.D. Hughes, P. Santer, C. Fernandez-Hernando, H. Tilg, J. Willeit, S. Kiechl, M. Mayr (United Kingdom) 12:03 ASSOCIATIONS BETWEEN LIPOPROTEIn SUBFRACTIONS AND GENOMEWIDE DNA METHYLATION In KORA F4 313 L. Pfeiffer, R. Wilson, H. Grallert, E. Reischl, A. Peters, C. Gieger, S. Wahl, M. Waldenberger (Germany) A. Lindau, C. Haerdtner, F.K. Swirski, P. Libby, L. Hein, C. Bode, A. Zirlik, I. Hilgendorf (Germany) 12:16 DEFICIENCY Of SECRETED IgM ANTIBODIES CAUSES INCREASED PLASMA IgE LEVELS THAt PROMOTE ATHEROSCLEROSIS 310 H. Colhoun (United Kingdom) 11:50 CIRCULATING MICRORNA-122 IS ASSOCIATED WITH INCIDENT METABOLIC SYNDROME AND TYPE-2 DIABETES H. Winkels, S. Meiler, C. Spitz, C. Buerger, A. Faussner, J. Borst, C. Weber, E. Lutgens, N. Gerdes 12:03 EARLY ATHEROPROTECTION BY SYK INHIBITION FAILS In ESTABLISHED DISEASE WHEN LOCAL MACROPHAGE PROLIFERATION DOMINATES LESION PROGRESSION 11:00 NOVEL BIOMARKERS FOR CVD In METABOLIC DISORDERS 11:25 CIRCULATING CELLS AND CVD RISK 304 L. Yvant-Charvet (France) 76 11:00 - 12:30 307 12:16 PLASMA LIPIDOMIC PROFILES IMPROVE UPON CONVENTIONAL RISK FACTORS TO PREDICT CARDIOVASCULAR EVENTS 314 P. Mundra, C. Barlow, N. Mellett, K. Huynh, Z. Alshehry, G. Wong, B. Kingwell, P. Nestel, P. Thompson, D. Sullivan, E. Barnes, J. Simes, A. Tonkin, P. Meikle (Australia) 77 Wednesday, June 1, 2016 11:00 - 12:30W. Auerswald Hall 11:00 - 12:30F. Pregl Hall Workshop: New Guidelines on Prevention of Cardiovascular Disease in Clinical Practice Workshop 2.4: Novel Role of Lipoprotein Receptors Chair: A. Catapano (Italy) 315 Chair: M. Piepoli (Italy) 316 11:00 INTRODUCTION: WHAt IS NEW In THESE GUIDELINES? 318 M. Piepoli (Italy) 11:05 HOW CAN WE IDENTIFY HIGH RISK? 320 321 A. Catapano (Italy) 11:50 POPULATION APPROACH TO PREVENT CVD 328 11:00 NOVEL ROLE Of ENDOTHELIAL RECEPTORS In ATHEROSCLEROSIS 329 A. von Eckardstein (Switzerland) 330 H. Bujo (Japan) 11:50 REGULATION Of HDL-C LEVELS VIA ABCA1: A ROLE FOR LRP1331 TBA 11:35 LIPIDS: WHAt IS NEW? 327 Chair: E. Steyrer (Austria) 11:25 SOLUBLE LR11, A CIRCULATING MARKER FOR ATHEROSCLEROSIS 319 I. Graham (Ireland) 11:20 WHAt ARE The RISK FACTOR TARGETS? Chair: A. von Eckardstein (Switzerland) 322 E. Bossano Prescott (Denmark) 12:05 PANEL DISCUSSION 323 12:25CONCLUSIONS 324 F. Oldoni, J. Van Capelleveen, M.M. Motazacker, J. Heeren, R. Sinke, G. Dallinga-Thie, D. Hui, K. Hovingh, J.A. Kuivenhoven (Netherlands) 12:03 SorLA IS A NOVEL HIGH AFFINITY PCSK9 RECEPTOR THAt INHIBITS ITS INACTIVATION BY FURIN 332 C. Gustafsen, S. Skeldal, S.L. Jensen, O.M. Andersen, C.M. Petersen, P. Madsen, S. Glerup (Denmark) 12:16 UNRAVELLING The MECHANISM AND IMPORTANCE Of BROWN ADIPOSE TISSUE WHOLE LIPOPROTEIn UPTAKE 333 A. Fischer, K. Gottschling, N. Mangels, M. Heine, J. Heeren (Germany) A. Catapano (Italy) M. Piepoli (Italy) 78 325 79 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria e c n a l G a t a e c Scien s n o i t a t n e s e r P E-Poster 80 www.eas2016.kenes.com Science at a Glance CALL FOR PAPERS Atherosclerosis Official Journal of the European Atherosclerosis Society Atherosclerosis publishes original papers and review articles reporting research findings and investigations into all aspects of atherosclerosis, its complications and related diseases. Encompassing: lipoprotein metabolism, disorders of lipid transport, arterial and vascular biology, including vascular imaging and flow studies, cardiovascular stem cell biology, thrombosis and inflammation. Papers covering genetics, metaanalysis and epidemiology of atherosclerosis are of interest, as are dietary studies and investigations into diabetes and hypertension as related to atherosclerosis and cardiovascular risk factors. Publisher, Koos Admiraal, [email protected] Editor-in-Chief: A. von Eckardstein If you have a specific question please contact our Editorial Assistant, S. Negrini, [email protected] BENEFITS OF PUBLISHING IN ATHEROSCLEROSIS • Seamless electronic editorial system, from online submission to article publication, with clear instructions and online tracking. • Improved presentation and the option to enrich your article with graphical abstracts, video, 3D images and linkage of content to relevant databases. • Rapid editorial processing and availability of accepted articles (2-3 weeks after acceptance) as “articles in press” • Advance notification of article publication via ScienceDirect’s alerting service • High visibility, with articles appearing in Scopus and PubMed shortly after publication • Unparalleled international readership via ScienceDirect, with 10 million active users monthly from over 120 countries. Over 80,000 Atherosclerosis articles are downloaded every month. • Atherosclerosis available via mobile Apps for increased accessibility • Authors receive quarterly updates of the number of downloads of their article • Open access publishing available BENEFITS OF PUBLISHING IN ATHEROSCLEROSIS Poster # Monday, May 30, 2016 13:00 - 14:00Exhibition Area Lipids and Lipoproteins SaG001 Chair: J. Heeren (Germany) 334 CONSEQUENCES OF DEFECTIVE LIPOLYSIS IN THE SMALL INTESTINE ON LIPID METABOLISM M. Korbelius, S. Obrowsky, S. Rainer, N. Vujic, D. Kratky (Austria) 335 SaG002 POSTTRANSCRIPTIONAL REGULATION OF THE LDLR BY ACTH TREATMENT - IMPORTANCE OF PCSK9 IN LIVER WHILE IDOL TAKES THE SCENE IN THE ADRENALS M. Ghosh Laskar, B. Angelin, M. Rudling (Sweden) 336 SaG003 TNF-ALPHA INDUCES PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) EXPRESSION IN HEPATIC HEPG2 CELL LINE IN A SOCS3-DEPENDENT MANNER M. Ruscica, Ricci, C. Macchi, P. Magni, L. Jingwen, A. Corsini, N. Ferri (Italy) 337 SaG004 A POTENTIAL ROLE OF CHOLESTEROL UPTAKE CAPACITY, A NEW MEASURE FOR HIGH-DENSITY LIPOPROTEIN FUNCTIONALITY, IN CORONARY RISK STRATIFICATION A. Harada, R. Toh, K. Murakami, M. Kiriyama, K. Yoshikawa, T. Kubo, K. Miwa, Y. Irino, K. Mori, N. Tanaka, T. Ishida, K. Hirata (Japan) 338 SaG005 LOW-DENSITY LIPOPROTEIN UPREGULATE SR-BI THROUGH SP1 SER702 PHOSPHORYLATION IN HEPATIC CELLS L. Wang, F. Yang, Y. Du, J. Zhang, B. Hong (China) 339 SaG006 SNPS LOCATED IN ABCA1, CETP AND APOA5/A4/C3/A1 ARE ASSOCIATED WITH PLASMA CHOLESTEROL EFFLUX C. Talbot, J. Plat, H. Popeijus, A. Ritsch, R. Mensink 340 SaG007 IDENTIFICATION OF A NOVEL APOLIPOPROTEIN THAT FACILITATES MTP-MEDIATED LIPID TRANSPORT H. Peng, C.S. Liu, T.Y. Chiu, H.T. Chen, J.J.Y. Yen, H.F. Yang-Yen (Taiwan) SaG008 BETA CELL-SPECIFIC DELETION OF ABCA1 AND ABCG1 REGULATES THE INCREASE OF SMALL NUCLEOLAR RNAS IN ADIPOCYTES F. Tabet, L. Hou, B. Cochran, L.F. Cuesta Torres, P.J. Barter, K.A. Rye (Australia) 341 342 Easy online submission at: http://ees.elsevier.com/ath More information on the types of papers we publish and further instructions for authors can be found at: www.atherosclerosis-journal.com 83 Science at a Glance Poster # Poster # 13:00 - 14:00Exhibition Area 13:00 - 14:00Exhibition Area Vascular Biology I Genetic, Omics and in silico Approaches Chair: G.R.Y. De Meyer (Belgium) 343 SaG009 HIGH-DENSUTY LIPOPROTEIN PHOSPHOLIPID CONTENT AND APOLIPOPROTEIN A-I LEVEL ARE DETERMINANTS OF CHOLESTEROL EFFLUX CAPACITY IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA 344 M. Ogura, M. Harada-Shiba (Japan) SaG010 SaG011 SaG012 SaG013 SaG014 SaG015 SaG016 84 A HIGH-THROUGHPUT SCREENING OF KINASE INHIBITORS IDENTIFIES A REGULATORY ROLE OF VEGF SIGNALING FOR TRANSENDOTHELIAL TRANSPORT OF HIGH-DENSITY LIPOPROTEINS S. Velagapudi, L. Rohrer, A. Von Eckardstein (Switzerland) 346 SMOOTH MUSCLE CELLS PCSK9 KNOCK-OUT EXHIBIT AN IMPAIRED RESPONSE TO PDGF STIMULATION S. Marchianò, G. Tibolla, A. Corsini, A.L. Catapano, N. Ferri (Italy) 347 5-METHOXYTRYPTOPHAN REDUCES NEOINTIMA FORMATION FOLLOWING ARTERIAL INJURY C.H. Chen, Y.C. Ho, H.H. Ho, C.H. Su, S.F. Yet (Taiwan) 348 SaG019 IMPACT OF FIBRE ORIENTATION IN FIBROUS CAP ON THE MECHANICAL LOADING IN HUMAN CORONARY ATHEROSCLEROTIC PLAQUES349 Z. Teng, G. Douglas, A. Brown, M. Sutcliffe, J. Gillard (United Kingdom) IN VITRO MIGRATION OF PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) INTO HUMAN HEALTHY AND DISEASED ARTERIES B. Jakic, C. Krapf, M. Buszko, G. Cappellano, M. Grimm, G. Wick (Austria) SaG018 345 MITOPHAGY ACTS AS A SAFEGUARD MECHANISM AGAINST HUMAN VASCULAR SMOOTH MUSCLE CELL APOPTOSIS INDUCED BY ATHEROGENIC LIPIDS H. Nahapetyan, A. Swiader, J. Faccini, R. D'Angelo, E. Mucher, M. Elbaz, P. Boya, C. Vindis (France) MDM2 E3 LIGASE-MEDIATED UBIQUITINATION AND DEGRADATION OF HDAC1 IN VASCULAR CALCIFICATION H. Kook, D.H. Kwon, G.H. Eom, S. Shin, E.M. Kim, Y.U. Lee, N. Choe (Republic of Korea) SaG017 350 351 Chair: N. Sanjana (USA) 352 GENE EXPRESSION PROFILES OF RECURRENT ACUTE PANCREATITIS RISK IN SEVERE HYPERTRIGLYCERIDEMIA K. Tremblay, D. Gaudet (Canada) 353 EVIDENCE FOR ENHANCED DE NOVO LIPOGENESIS AND UNCOUPLING OF OBESITY FROM TYPE 2 DIABETES RISK IN THE LOWEXPRESSION VARIANT CARRIERS OF FATTY ACID-BINDING PROTEIN 4 J. Saksi, P. Ijäs, A. Jula, H. Heikkilä, J. Tuimala, O. Dwivedi, T.M. Tuomi, L. Groop, M. Jauhiainen, P. Kovanen, P. Lindsberg (Finland) 354 THE PREVALENCE OF FAMILIAL HYPERLIPIDAEMIA AND HYPER-LIPOPROTEIN(A) IN MUTATION-NEGATIVE FAMILIAL HYPERCHOLESTEROLAEMIA AND ASSOCIATIONS WITH CARDIOVASCULAR EVENTS K. Ellis, J. Pang, D. Chan, A. Hooper, D. Bell, J. Burnett, G. Watts (Australia) SaG020 THE RS16900627 POLYMORPHISM OF THE RECEPTOR-INTERACTING PROTEIN 2 (RIP2) GENE IS ASSOCIATED WITH SUBCLINICAL ATHEROSCLEROSIS. THE GENETICS OF ATHEROSCLEROTIC DISEASE (GEA) MEXICAN STUDY G. Vargas-Alarcon, R. Posadas-Sánchez, J. Angeles-Martínez, E. AlvarezLeón, N. Pérez-Hernánez, J.M. Rodríguez-Pérez, J.M. Fragoso, G. Cardoso, T. Villarreal-Molina, C. Posadas-Romero (Mexico) SaG021 SaG022 RARE VARIANTS IN ABCG2 IDENTIFIED BY SEQUENCING MAY INFLUENCE THE LIPID RESPONSE TO ROSUVASTATIN TREATMENT M. Hu, J. Chan, B. Tomlinson (Hong Kong- China) CHARACTERISTICS OF HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA IN SPAIN R.M. Sánchez-Hernández, M. Stef, S. Perez-Calahorra, F. Almagro, P. Sáenz-Aranzubía, N. Plana, J.T. Real, F. Blanco-Vaca, J.F. Ascaso, F. Civeira, M. Pocovi (Spain) 355 356 357 358 SaG023 CLINICAL CHARACTERISTICS AND PREVALENCE OF CARDIOVASCULAR DISEASE RISK FACTORS IN SUBJECTS SCREENED FOR FAMILIAL HYPERCHOLESTEROLEMIA - A CROSS SECTIONAL STUDY IN THE NETHERLANDS359 M.L. Hartgers, J. Besseling, B. Lucius, L. Kutikova, G.K. Hovingh (Netherlands) SaG024 LOOKS LIKE FH BUT IT'S NOT FH - EXTENDED LIPID PROFILE OF PAEDIATRIC CLINICAL FH PATIENTS REVEALS A DIFFERENT LIPID PROFILE IN FH NEGATIVE PATIENTS A.M. Medeiros, M. Bourbon, P. Aguiar (Portugal) 360 85 Science at a Glance Poster # Poster # 13:00 - 14:00Exhibition Area 14:00 - 15:00Exhibition Area CV Risk Factors and Atherosclerosis I Experimental Cadiovascular Medicine I Chair: Y. Matsuzawa (Japan) SaG025 SaG026 SaG027 SERUM PHOSPHATIDYLCHOLINE PLASMALOGEN AND ALKYLPHOSPHATIDYLCHOLINE CONCENTRATIONS ARE INVERSELY ASSOCIATED WITH MYOCARDIAL INFARCTION INCIDENCE IN PATIENTS WITH PERIPHERAL ARTERY DISEASE J. Moxon, R. Jones, G. Wong, D. Liu, J. Weir, R. Behl-Gilhotra, B. Kingwell, P. Meikle, J. Golledge (Australia) SaG029 SaG032 86 362 SaG034 363 ANTI-APOLIPOPROTEIN A-1 ANTIBODIES AS A NOVEL CARDIOVASCULAR RISK FACTOR: RESULTS FROM THE COLAUS STUDY N. Vuilleumier (Switzerland) 364 REMNANT CHOLESTEROL PREDICTS CARDIOVASCULAR EVENT RISK IN PATIENTS WITH TYPE 2 DIABETES INDEPENDENTLY FROM THE BASELINE CORONARY ARTERY DISEASE STATE C. Saely, D. Zanolin, P. Rein, A. Vonbank, A. Leiherer, A. Muendlein, H. Drexel (Austria) SaG030 THE PROSPECTIVE RELATIONSHIPS OF CIRCULATING AND URINARY CHOLINE METABOLITES WITH INCIDENT TYPE 2 DIABETES AMONG PATIENTS WITH SUSPECTED STABLE ANGINA PECTORIS G.F.T. Svingen, H. Schartum-Hansen, E.R. Pedersen, P.M. Ueland, G.S. Tell, G. Mellgren, P.R. Njølstad, R. Seifert, E. Strand, T. Karlsson, O.K. Nygård (Norway) SaG031 SaG033 SERUM ACYLCARNITINES AND RISK OF INCIDENT TYPE 2 DIABETES IN PATIENTS WITH SUSPECTED STABLE ANGINA PECTORIS - A PROSPECTIVE COHORT STUDY E.W. Rebnord, E. Strand, G.F.T. Svingen, P.R. Njølstad, G. Mellgren, G.S. Tell, R.K. Berge, A. Svardal, O.K. Nygård, E.R. Pedersen (Norway) SaG028 REDUCTION IN PLASMA CHOLESTEROL EFFLUX CAPACITY FROM HUMAN MACROPHAGES IS ASSOCIATED WITH THE APPEARANCE OF CLINICAL FEATURES OF METABOLIC SYNDROME J. Gall, E. Frisdal, R. Bittar, W. Le Goff, E. Bruckert, P. Lesnik, M. Guerin, P. Giral (France) Chair: P. Parini (Sweden) 361 365 366 SaG035 SaG036 SaG037 ASSOCIATIONS OF TRIGLYCERIDES WITH PERCENT BODY FAT IN ADOLESCENTS: THE PEP FAMILY HEART STUDY T. Bertsch, G.M. Haas, E. Liepold, P. Schwandt (Germany) 368 HEPATITIS C VIRUS (HCV) AND ATHEROSCLEROSIS RISK: A ROLE FOR LOW-DENSITY IMMUNE COMPLEXES? M. Bassendine, S. Nielsen, D. Neely (United Kingdom) 369 HEPATIC MIRNA EXPRESSION PROFILING IN GENETICALLY MODIFIED MOUSE MODELS OF DIFFERENT ATHEROSCLEROSIS SUSCEPTIBILITY S. Manzini, M. Busnelli, M. Chiara, C. Parolini, F. Dellera, G.S. Ganzetti, D.S. Horner, G. Chiesa (Italy) 371 372 ESTRADIOL PROTECTS OVARIECTOMIZED FEMALE RATS AGAINST FRUCTOSE RICH DIET INDUCED CARDIAC INFLAMMATION M. Bundalo, M. Zivkovic, G. Koricanac, A. Stankovic (Serbia) 373 IMPACT OF ENDOTHELIAL LIPASE OVEREXPRESSION ON CHOLESTEROL EFFLUX CAPACITY OF SERUM, APOLIPOPROTEIN B-DEPLETED SERUM AND HDL I. Schilcher, A. Hrzenjak, T. Eichmann, T. Stojakovic, H. Scharnagl, G. Marsche, S. Frank (Austria) 374 SR-BI INVOLVED ON PLASMA HDL2-APOA-I RECIRCULATION TO PREbHDL IN MICE M. Tsujita, T. Yokota, N. Akita, F.J. Gonzalez, S. Yokoyama (Japan) 375 SaG038 MICE ABUNDANT IN MURICHOLIC BILE ACIDS SHOW RESISTANCE TO DIETARY INDUCED STEATOSIS, WEIGHT GAIN, AND TO IMPAIRED GLUCOSE METABOLISM Y. Bonde, G. Eggertsen, M. Rudling (Sweden) SaG039 367 THE ROLE OF MICRO RNAS AND THEIR TARGETS IN A CAROTID ARTERY INTIMAL HYPERPLASIA Y.U. Lee, N. Choe, E.M. Kim, S. Shin, D.H. Kwon, T. Kook, H. Kook (Republic of Korea) 370 IMPACT OF LITOMOSOIDES SIGMODONTIS ANTIGEN ON T CELL DIFFERENTIATION AND ON THE DEVELOPMENT OF INITIAL ATHEROSCLEROTIC LESIONS IN APOE-KNOCKOUT MICE C. Kühn, M. Tauchi-Brück, J. Ajendra, A. Hörauf, C. Stumpf, S. Achenbach, M. Hübner, B. Dietel (Germany) SaG040 UNSTABLE LDL - NOVEL MECHANISM OF ATHEROGENESIS AND LINK TO CARDIOVASCULAR DEATHS M. Ruuth, S.D. Nguyen, T. Vihervaara, T.D. Laajala, M. Uusitupa, U. Schwab, M. Savolainen, J. Sinisalo, T. Aittokallio, R. Käkelä, M. Jauhiainen, P. Kovanen, K. Oörni (Finland) 376 377 378 87 Science at a Glance Poster # Poster # 14:00 - 15:00Exhibition Area 14:00 - 15:00Exhibition Area Nutrition, Nutraceuticals and Cardiovascular Disease Pharmacology of Dyslipidemia Chair: A.H. Lichtenstein (USA) SaG041 MIDDLE-TERM DIETARY SUPPLEMENTATION WITH RED YEAST RICE PLUS COENZYME Q10 IMPROVES LIPID PATTERN, ENDOTHELIAL REACTIVITY AND ARTERIAL STIFFNESS IN MODERATELY HYPERCHOLESTEROLEMIC SUBJECTS A. Cicero, M. Morbini, M. Rosticci, S. D'Addato, E. Grandi, C. Borghi (Italy) SaG042 INCREASED OXIDATIVE STRESS AND IMPAIRED MITOCHONDRIAL BIOGENESIS AND DYNAMICS ARE IMPROVED BY RICE BRAN ENZYMATIC EXTRACT DIET SUPPLEMENTATION C. Perez Ternero, C. Werner, M. Alvarez de Sotomayor, M.D. Herrera, U. Laufs (Spain) SaG043 INVESTIGATION OF THE IMPACT OF CROCUS SATIVUS ON THE METABOLIC PROFILE OF DIABETIC RATS P. Konstantopoulos, L.M. Korou, I. Vlachos, I. Doulamis, A. Tzani, S. Fragouli, G. Mastorakos, Ν. Katsilambros, D. Perrea (Greece) SaG044 LONG-CHAIN METABOLITES OF Α-TOCOPHEROL EMERGE FROM THE SHADOW OF THEIR PRECURSORS: Α-13’-OH AND Α-13’-COOH AS A NEW CLASS OF REGULATORY METABOLITES L. Schmölz, M. Wallert, S. Ciffolilli, S. Kluge, G. Cruciani, M. Glei, O. Werz, F. Galli, M. Birringer, S. Lorkowski (Germany) SaG045 CONSUMPTION OF POLYUNSATURATED FAT IMPROVES THE SATURATED FATTY ACID-MEDIATED IMPAIRMENT OF HDL ANTIOXIDANT POTENTIAL A. García León, L. Cedó, J. Metso, D. Santos, J.L. Sánchez-Quesada, J. Julve, J. Mora-Brugués, M. Jauhiainen, F. Blanco-Vaca, J.C. Escolà-Gil (Spain) SaG046 PLASMA LEVELS OF THE PRO-ATHEROGENIC NUTRIENT BIOMARKER TMAO IS INCREASED BY EXPOSURE TO DIOXIN-LIKE POLLUTANTS THROUGH UPREGULATION OF FMO3 M. Petriello, J. Hoffman, M. Sunkara, A. Morris, B. Hennig (USA) SaG047 SOYA-ENRICHED MIXED DIET SIGNIFICANTLY IMPROVES CARDIOVASCULAR AND METABOLIC RISK FACTORS: A RANDOMIZED CONTROLLED TRIAL M. Ruscica, C. Pavanello, B. Morlotti, M. Gomaraschi, C. Vitali, R. Bosisio, C.R. Sirtori, A. Arnoldi, P. Magni (Italy) SaG048 PREVALENCE AND 2010-15 SECULAR TRENDS IN SUGAR-SWEETENED BEVERAGES SALES IN EUROPE AND THE MIDDLE EAST B. Arsenault, M.R. Taskinen, J.P. Després (Canada) 88 Chair: M. Averna (Italy) 379 380 SaG049 ATTAINMENT OF ACC/AHA RECOMMENDED LDL-C LOWERING WITH STATIN AND EZETIMIBE STATIN THERAPIES P. Toth, H. Bays, M. Farnier, E. Jensen, J. Tomassini, A. Polis, J. Foody, A. Tershakovec (USA) 381 SaG050 EFFICACY AND SAFETY OF PITAVASTATIN IN PAEDIATRIC FH COMPARED WITH OTHER STATINS FROM COCHRANE DATABASE M. Harada-Shiba, T. Ohta, A. Ohtake, T. Okada, O. Arisaka, J. Kastelein, I. Luirink (Japan) SaG051 382 SaG052 383 SaG053 384 385 386 387 SaG054 SaG055 SaG056 HOW TO IMPROVE THE CHOLESTEROL-LOWERING EFFICACY OF EZETIMIBE IN STATIN-INTOLERANT PATIENTS IN CLINICAL PRACTICE: A RETROSPECTIVE STUDY A. Cicero, M. Morbini, S. D'Addato, F. Fogacci, M. Rosticci, C. Borghi (Italy) IDENTIFICATION AND MANAGEMENT OF CANADIAN PATIENTS WITH SYMPTOMS OF STATIN INTOLERANCE: RESULTS FROM A REAL-WORLD CLINICAL PRACTICE SURVEY P. Oh, G.K. Hovingh, S.R. Gandra, J. McKendrick, R. Dent, H.M. Wieffer, A.L. Catapano, R.S. Rosenson, E.S.G. Stroes (Switzerland) PCSK9 CIRCULATING LEVELS AND CETP PLASMA ACTIVITY ARE ASSOCIATED INDEPENDENTLY OF LIPID LOWERING THERAPIES J. Girona, D. Ibarretxe, N. Plana, S. Guaita, N. Amigó, M. Heras, L. Masana (Spain) UNDERSTANDING LIPOPROTEIN(A) METABOLISM: REBOUND ANALYSES OF LIPOPROTEIN(A) AND PCSK9 CONCENTRATIONS FOLLOWING REGULAR LIPOPROTEIN APHERESIS TREATMENT (THE LIPARE-STUDY) E. Waldmann, E.M. Ooi, P.H.R. Barrett, D.C. Chan, S.M. Marcovina, G.F. Watts, K.G. Parhofer (Germany) DPP4 INHIBITOR, ANAGLIPTIN, AMELIORATES FASTING AND POSTPRANDIAL HYPERTRIGLYCERIDEMIA M. Sairyo, D. Masuda, T. Kobayashi, H. Matsuda, T. Okada, R. Kawase, K. Nakatani, M. Koseki, T. Ohama, M. Nishida, Y. Sakata, S. Yamashita (Japan) FAMILIAL HYPERCHOLESTEROLEMIA IN PRIMARY CARE IN GERMANY - DIABETES AND CARDIOVASCULAR RISK EVALUATION: TARGETS AND ESSENTIAL DATA FOR COMMITMENT OF TREATMENT (DETECT) STUDY N. Schmidt, B. Schmidt, A. Dressel, U. Fraass, I. Gergei, J. Klotsche, L. Pieper, H. Scharnagel, M.E. Kleber, W. März, H.U. Wittchen, T. Grammer (Germany) 388 389 390 391 392 393 394 395 396 89 Science at a Glance Poster # Poster # 14:00 - 15:00Exhibition Area Tuesday, May 31, 2016 Imaging in Vascular Dysfunction and Myocardial Infarction Chair: W. Koenig (Germany) SaG057 A NOVEL TC-99M AND FLUORESCENCE LABELED PEPTIDE AS A MULTIMODAL IMAGING AGENT FOR TARGETING ANGIOGENESIS IN A MURINE HINDLIMB ISCHEMIA MODEL D.W. Kim, S.G. Kim, M.H. Kim, C.G. Kim (Republic of Korea) 397 13:00 - 14:00Exhibition Area CV Risk Factors and Atherosclerosis II 398 Chair: W. März (Germany) SaG065 SaG058 REPRODUCIBILITY OF ENDOTHELIAL SHEAR STRESS AND LOW DENSITY LIPOPROTEIN TRANSPORT MODELING IN COMPUTED TOMOGRAPHY ANGIOGRAPHIC IMAGING DATA A. Sakellarios, C.V. Bourantas, S.L. Papadopoulou, T. De Vries, P.H. Kitslaar, C. Gyrasis, K.K. Naka, S. Veldhof, G.W. Stone, J.H.C. Reiber, L.K. Michalis, P.W. Serruys, P.J. De Feyter, H.M. Garcia Garcia, D.I. Fotiadis (Greece) SaG059 USAGE OF NOVEL HYBRID PIXEL DETECTORS FOR NATIVE ATHEROSCLEROTIC PLAQUE IMAGING BY HIGH RESOLUTION X-RAY COMPUTED TOMOGRAPHY A. Zhemchugov, A. Svetlikov, D. Kozhevnikov, G. Shelkov, S. Urazgildeeva, V. Gurevich (Russia) SaG060 COMPOSITION OF CORONARY PLAQUES BY CT ANGIOGRAPHY: VALIDATION BY NEAR-INFRARED SPECTROSCOPY J.A. Goldstein, R.D. Madder, S. Dixon (USA) SaG061 SaG062 SaG063 ACTIVATED-PLATELET TARGETED FIBRINOLYTIC DRUGS: NOVEL TARGETED-THERANOSTIC MICROBUBBLES FOR SIMULTANEOUS DIAGNOSIS, TREATMENT AND MONITORING USING MOLECULAR ULTRASOUND TECHNOLOGY X. Wang, K. Peter (Australia) CARDIOVASCULAR EVENTS IN PATIENTS TREATED BY LIPOPROTEIN APHERESIS (LA) - ANALYSIS OF POSSIBLE REASONS S. Tselmin, S. Fischer, F. Pistrosch, G. Müller, U. Julius (Germany) THE RELATIONSHIP BETWEEN INSULIN LIKE GROWTH FACTOR-1 AND CORONARY ARTERY CALCIUM SCORE IN CARDIOVASCULAR ASYMPTOMATIC ADULT MEN K.C. Park, M.J. Kim, K.C. Kim, B.H. Choi, K.H. Park, H.C. Cho (Republic of Korea) SaG064 2013 ACC/AHA VERSUS 2004 NCEP ATP III GUIDELINES IN THE PREDICTION OF CORONARY ARTERY CALCIFICATION PROGRESSION IN A KOREAN POPULATION C.H. Jung, S. Kim, W.J. Lee, J.Y. Park, C.Y. Park (Republic of Korea) 399 SERUM LEVELS OF ANTI-APOLIPOPROTEIN A-1 IGG ARE ASSOCIATED WITH LONG-TERM DISABILITY AND CEREBRAL LESION VOLUME IN ACUTE ISCHEMIC STROKE PATIENTS 406 407 N. Satta, F. Carbone, F. Montecucco, J. Virzi, F. Burger, A. Roth, G. Roversi, C. Tamborino, I. Casetta, S. Seraceni, A. Trentini, M. Padroni, F. Dallegri, P. Lalive, F. Mach, E. Fainardi, N. Vuilleumier (Switzerland) SaG066 GLYCATION OF APOA-I LINKS DIABETES AND CVD 408 J. Domingo-Espin, O. Nilsson-Wolanin, J. Dalla-Riva, K. Bernfur, M. Lindahl, J. Lagerstedt (Sweden) 400 SaG067 APOLIPOPROTEIN CII AND CIII: PROGNOSTIC MARKERS OF CARDIOVASCULAR RISK? 409 H. Scharnagl, M.E. Kleber, T.B. Grammer, T. Stojakovic, M.M. Hoffmann, W. März (Austria) 401 SaG068 SERUM MMP-8 AND TIMP-1 ASSOCIATE WITH INCIDENT CVD EVENTS AND ALL-CAUSE MORTALITY IN A POPULATION-BASED COHORT 410 I. Kormi, A.S. Havulinna, V. Salomaa, T. Tervahartiala, T. Sorsa, P.J. Pussinen (Finland) 402 SaG069 PLASMA CONCENTRATIONS OF AFAMIN ARE ASSOCIATED WITH THE PREVALENCE AND INCIDENCE OF TYPE 2 DIABETES MELLITUS 411 B. Kollerits, C. Huth, S. Kiechl, C. Lamina, C. Meisinger, C. Herder, L. Kedenko, J. Willeit, B. Thorand, D. Dähnhardt, D. Stöckl, M. Roden, W. Rathmann, B. Paulweber, A. Peters, H. Dieplinger, F. Kronenberg (Austria) 403 SaG070 OMENTIN-1 AND RISK OF STROKE: RESULTS FROM THE EPIC-POTSDAM COHORT STUDY 412 J. Menzel, R. Di Giuseppe, R. Biemann, C. Wittenbecher, K. Aleksandrova, T. Pischon, A. Fritsche, M.B. Schulze, H. Boeing, B. Isermann, C. Weikert (Germany) 404 SaG071 405 AGE, GENDER AND BLOOD LIPID LEVELS: A CHANCE TO IMPROVE CARDIOVASCULAR RISK ASSESSMENT 413 W. Balder, J.K. De Vries, I.M. Nolte, J.A. Kuivenhoven, P.W. Kamphuisen (Netherlands) SaG072 THE ADDED VALUE OF AORTIC PWV BEYOND TRADITIONAL RISK FACTORS IN CARDIOVASCULAR RISK STRATIFICATION 414 B. Benczur, R. Bocskei, A. Cziraki, M. Illyes (Hungary) 90 91 Science at a Glance Poster # Poster # 13:00 - 14:00Exhibition Area 13:00 - 14:00Exhibition Area Vascular Biology II Insulin Resistance, Diabetes, Metabolic Syndrome and Obesity Chair: H. Stangl (Austria) SaG073 ENDOTHELIAL DYNAMIC CHANGES IN CHONDROITIN SULFATE AND DERMATAN SULFATE PROTEOGLYCANS INDUCED BY VERY LOW DENSITY LIPOPROTEINS 415 Chair: G. Watts (Australia) 416 SaG081 R.E. Oberkersch, Y. Rasente, S. Yuschak, N. Volpi, G. Calabrese (Argentina) SaG074 PRO-ATHEROGENIC OXIDIZED-LDL/Β2-GLYCOPROTEIN I COMPLEXES IN CORONARY ARTERY DISEASE PATIENTS ARE ASSOCIATED WITH DISEASE SEVERITY PAI-1 EXPRESSION RENDERS M2 POLARIZED MACROPHAGES PROTEOLYTICALLY QUIESCENT 417 IN VITRO EVIDENCE OF A PRO-INFLAMMATORY ACTION OF PCSK9 IN THP-1-DERIVED MACROPHAGES INCREASED MITOCHONDRIAL ROS ACCELERATE ATHEROSCLEROSIS IN MITOCHONDRIAL CATALYTIC ENZYME 3 DEFICIENT MICE COMPARATIVE EFFECT OF SILYMARIN AND SILYBIN TREATMENT ON INFLAMMATION AND OXIDATIVE STRESS IN TRANSGENIC SPONTANEOUSLY HYPERTENSIVE RATS OVEREXPRESSING HUMAN C-REACTIVE PROTEIN 419 PONATINIB AUGMENTS VASOCONSTRICTION AND ATTENUATES VASORELAXATION IN MOUSE AORTIC RINGS J. Jalkanen, M. Maksimow, S. Jalkanen, H. Hakovirta (Finland) 92 428 N. García-Casares, J. García-Arnés, A. Gutiérrez-Cardo, J. Rioja, M.J. Ariza, F. Alfaro, A. Nabrozidis, P. González-Santos (Spain) SaG085 COMPONENTS OF THE METABOLIC SYNDROME AND RISK OF TYPE 2 DIABETES429 S. Marott, B. Nordestgaard, A. Tybjærg-Hansen, M. Benn (Denmark) 421 SaG086 THE PLASMA PROTEOME OF TANGIER DISEASE PATIENTS REVEALS PERTURBATIONS OF DIABETIC AND INFLAMMATORY PATHWAYS 430 J. McParland, E. Pashos, D. Rader, M. Cuchel (USA) SaG087 422 A. Kirsch, R. Kirchmair, S. Frank (Austria) SaG080 CARDIOVASCULAR RISK FACTORS DIFFER IN INFLAMMATION PATHOLOGY IN PATIENTS WITH CLINICALLY SYMPTOMATIC LOWER LIMB ATHEROSCLEROSIS SaG084 WAIST CIRCUMFERENCE AND BODY MASS INDEX CORRELATE WITH CEREBRAL GLUCOSE METABOLISM IN THE TEMPORAL LOBE IN DIABETIC PATIENTS 420 O. Oliyarnyk, H. Malinska, I. Markova, J. Trnovska, V. Skop, L. Kazdova, R. Vecera, M. Pravenec (Czech Republic) SaG079 427 S. Afzal, A. Tybjærg-Hansen, G.B. Jensen, B.G. Nordestgaard (Denmark) S.H. Park, S.K. Hur, J.Y. Yoo, S.J. Jeong, G.T. Oh (Republic of Korea) SaG078 426 Y. Liu, T. Siahmansur, J.D. Schofield, S. Hama, R. Yadav, S. Adam, M. France, S. Kwok, R. Donn, A. Stevens, J. Ho, B.J. Ammori, A. Syed, P.N. Durrington, H. Soran (United Kingdom) SaG083 BODY MASS INDEX AND MORTALITY OVER 3 DECADES C. Ricci, A. Corsini, N. Ferri (Italy) SaG077 SaG082 EFFECTS OF OBESITY AND BARIATRIC SURGERY ON HDL FUNCTIONALITY AND MICROVASCULAR COMPLICATIONS OF OBESITY 418 P. Hohensinner, J. Baumgartner, B. Ebenbauer, B. Thaler, D. Konstantin, C. Kaun, S. Stoijkovic, M. Fischer, G. Maurer, K. Huber, J. Wojta (Austria) SaG076 BARIATRIC SURGERY-INDUCED WEIGHT LOSS IN MORBIDLY OBESE PATIENTS PROMOTES A FAVORABLE DECREASE IN THE GENE EXPRESSION OF MARKERS OF SUBCUTANEOUS ADIPOSE TISSUE HOMEOSTASIS425 J. Julve, E. Pardina, R. Ferrer, J. Rossell, J.A. Baena-Fustegueras, J.M. Fort, A. Lecube, J. Peinado-Onsurbe (Spain) L.R. Lopez, K.P. Bliden, R. Chaudhary, R. Damrongwatanasuk, K.E. Guyer, M.G. Gesheff, C.J. Franzese, U.S. Tantry, P.A. Gurbel (USA) SaG075 424 423 ROLE OF PCSK9 (PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9) IN OBESITY AND METABOLIC SYNDROME: BEYOND LDLR TARGETING 431 G. Balzarotti, G. Tibolla, M. Ruscica, M. Stramba-Badiale, A.L. Catapano, D.G. Norata (Italy) SaG088 DIPEPTIDYL PEPTIDASE-4 INHIBITORS AND PROTECTION AGAINST STROKE: A SYSTEMATIC REVIEW AND META-ANALYSIS 432 F. Barkas, M. Elisaf, V. Tsimihodimos, H. Milionis (Greece) 93 Science at a Glance Poster # Poster # 13:00 - 14:00Exhibition Area 14:00 - 15:00Exhibition Area Hypertension, Liver and Chronic Renal Disease Experimental Cadiovascular Medicine II Chair: A. Zambon (Italy) SaG089 PRO-ATHEROGENIC LIPOPROTEIN PROFILE ASSOCIATED WITH WHITE MATTER LESIONS IN CHRONIC KIDNEY DISEASE PATIENTS: A 1H-NMR METABOLOMIC APPROACH 433 SaG097 434 N. Amigó, R. Fuertes, C. Cabré, M. Vinaixa, M. Romeu, M. Muñoz, M. Giralt, J. Soler, J. Aquilera, M.T. Compte, X. Correig, A. Martínez-Vea (Spain) SaG090 ALTERED INFLAMMATORY PARAMETERS AND CHEMERIN LEVELS AFTER RENAL TRANSPLANTATION RENAL DISEASE IS ASSOCIATED WITH MODIFIED PON1 DISTRIBUTION AT HDL SUBCLASSES M.C. Duta-Mare, B. Radovic, S. Schlager, M. Wegscheider, D. Kolb-Lenz, T. Madl, S. Stryeck, D. Kratky (Austria) HEPATIC TRANSCRIPTOMIC SIGNATURES IN A MOUSE MODEL OF THE METABOLIC SYNDROME 435 SaG099 THE ATHEROPROTECTIVE ACTIVITY OF GANODERMA AND ITS ACTION MECHANISM IN MICE STRONGLY INCREASING PREVALENCE OF HYPERTENSION BY INCREASING OVERWEIGHT IN CHILDREN AND ADOLESCENTS 436 SaG100 SaG101PPARΓ ACTIVATION ATTENUATES OXIDATIVE STRESS AND IMPROVES CEREBRAL ARTERIES ENDOTHELIAL DYSFUNCTION IN AGING RAT THROUGH UP-REGULATING UCP2 438 LIVER DISEASE ALTERS HIGH-DENSITY LIPOPROTEIN COMPOSITION, METABOLISM AND FUNCTION SaG103 440 94 448 GENETIC CORRELATIONS BETWEEN CIRCULATING MIRNAS AND LIPID PROFILES REVEAL NOVEL BIOMARKERS OF CVD RISK 449 L. Michael, S. McAhren, S. Kumar, J. Peralta, H. Kulkarni, W. Gerard, J. Weir, C. Barlow, M. Kowala, P. Meikle, J. Blangero, J. Curran (USA) M. Trieb, V. Stadlbauer, R. Birner-Gruenberger, G. Marsche (Austria) N.A. Mohd Kasim, R. Rahmat, S. Abdul Razak, S. Muid, T. Rahman, H. Nawawi (Malaysia) EFFECTS OF CHRONIC INFLAMMATION ON MEGAKARYOCYTE AND PLATELET FUNCTION IN A CONDITIONAL MOUSE MODEL M. Salzmann, M. Haase, C. Arzt, M. Mussbacher, A. Assinger, J.A. Schmid (Austria) 439 SaG096 ENHANCED STATUS OF PROTHROMBOGENESIS AND ITS ASSOCIATION WITH SERUM LDL-C LEVELS IN SUBJECTS WITH FAMILIAL HYPERCHOLESTEROLAEMIA441 447 P. Wang, G. Cai, F. Wang, P. Zhou, Q. Wang (China) SaG102 B.M. Choi, Y.O. Kim, H.C. Song, Y.B. Lee (Republic of Korea) SaG095 THE APOE*3LEIDEN.GK+/- MOUSE AS NOVEL TRANSLATIONAL MODEL FOR DYSLIPIDEMIA, TYPE 2 DIABETES AND MACROVASCULAR COMPLICATIONS446 M. Pouwer, S. Heinonen, M. Behrendt, A.C. Andréasson, E. Pieterman, A. Van den Hoek, W. Jukema, B. Leighton, A.C. Jönsson-Rylander, H. Princen (Netherlands) 437 G.M. Haas, E. Liepold, T. Bertsch, P. Schwandt (Germany) SaG094 ASSOCIATION OF CORONARY ARTERY CALCIFICATION AND ARTERIAL MICRO-CALCIFICATION OF THE VASCULAR ACCESS IN INCIDENT HEMODIALYSIS PATIENTS 445 F.E. Mo, P.L. Hsu, Y.C. Lin (Taiwan) D. Nasias, I. Evangelakos, D. Kardassis (Greece) SaG093 444 S. Kim, S.J. Jeong, G.T. Oh (Republic of Korea) M. Miljkovic, J. Kotur-Stevuljevic, A. Stefanovic, J. Vekic, A. Zeljkovic, T. Gojkovic, S. Simic-Ogrizovic, V. Spasojevic-Kalimanovska, Z. JelicIvanovic (Serbia) SaG092 442 CONSEQUENCES OF LYSOSOMAL ACID LIPASE DEFICIENCY IN MACROPHAGES443 SaG098 PEROXIREDOXIN 1 HAVE PROTECTIVE ROLE IN THE VASCULAR DISEASE BY REGULATING MACROPHAGES R. Szentimrei, M. Harangi, H. Lőrincz, E.V. Varga, A. Szentpéteri, P. Fülöp, I. Seres, G. Paragh (Hungary) SaG091 Chair: M. Jauhiainen (Finland) SaG104 ELEVATED LDL AND OXIDATIVE STRESS CONTRIBUTE TO ARRHYTHMOGENIC CARDIOMYOPATHY PHENOTYPIC MANIFESTATION 450 L. Arnaboldi, I. Stadiotti, S. Brambilla, G. Milano, A. Scopece, F. Cattaneo, A. Granata, C. Tondo, A. Corsini, G. Pompilio, E. Sommariva (Italy) 95 Science at a Glance Poster # Poster # 14:00 - 15:00Exhibition Area 14:00 - 15:00Exhibition Area Immunity and Atherosclerosis Emerging Aspects in Pharmacological Treatment of Primary and Secondary Dyslipidemia Chair: G. Caligiuri (France) SaG105 SaG106 A NOVEL MECHANISM OF STATINS IN ATHEROSCLEROTIC AND IN HIGH-RISK SUBJECTS: MODULATION OF THE ADIPONECTIN RECEPTOR PATHWAY IN CIRCULATING MONOCYTES 451 Chair: B. Dieplinger (Austria) K. Gasbarrino, H. Zheng, S.S. Daskalopoulou (Canada) EFFICACY AND SAFETY OF LONG-TERM COADMINISTRATION OF FENOFIBRATE AND EZETIMIBE IN PATIENTS WITH COMBINED HYPERLIPIDEMIA: RESULTS OF THE EFECTL TRIAL NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AND THE RISK OF STROKE IN PATIENTS WITH RHEUMATOID ARTHRITIS S. Oikawa, S. Yamashita, N. Nakaya, J. Sasaki, S. Kono, G. EFECTL Study Investigators (Japan) 452 453 Y.R. Chen, H. Fang-I, W. Hsin-Chiao, C. Hung-Yi (Taiwan) SaG107 THE PROTEIN COMPOSITION OF INTIMA AND MEDIA THORACIC AORTA LAYERS IN ATHEROSCLEROSIS WITH AUTOANTIGENS DETECTION AND IDENTIFICATION USING PROTEOMIC TECHNOLOGIES SaG114 EXPRESSION OF E06, A NATURAL MONOCLONAL ANTIBODY TARGETED TO OXIDIZED PHOSPHOLIPIDS (OXPL), ATTENUATES THE PROGRESSION OF AORTIC SCLEROSIS IN AGED HYPERLIPIDEMIC MICE SaG115 SaG109 CCL22/ MACROPHAGE-DERIVED CHEMOKINE EXPRESSION VIA HISTAMINE IN THE ATHEROSCLEROSIS SaG116 SOLUBLE URIC ACID PROMOTES DEVELOPMENT OF ATHEROSCLEROSIS LESIONS VIA ENHANCEMENT OF INNATE INFLAMMATION IN MICE 456 SaG117 457 Y. Kimura, T. Yanagida, A. Onda, K. Asako, H. Kikuchi, H. Kono (Japan) SaG111 PENTRAXIN 3 PLAYS A KEY ROLE IN THE IMMUNOMODULATION OF DIET INDUCED-OBESITY IN MICE REGULATORY CD19+CD24HICD38HI B CELLS ARE DECREASED IN PATIENTS WITH CORONARY ATHEROSCLEROSIS AND HAVE IMPAIRED INTERLEUKIN-10 PRODUCTION IN RESPONSE TO CPG 463 OMEGA-3 CARBOXYLIC ACIDS IN SEVERE HYPERTRIGLYCERIDEMIA: EVOLVE II STUDY RESULTS 464 CARDIOVASCULAR EVENT RATES IN HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH): TRIAL ASSESSING LONG-TERM USE OF PCSK9 INHIBITION IN SUBJECTS WITH GENETIC LDL DISORDERS (TAUSSIG) STUDY INTERIM RESULTS 465 F. Raal, C. Kurtz, N. Honarpour, L. Tang, E.A. Stein (South Africa) 458 SaG118 A. Moregola, F. Bonacina, U. Guerrini, E. Bonavita, C. Garlanda, A. Mantovani, A.L. Catapano, G.D. Norata (Italy) SaG112 PHARMACODYNAMIC RELATIONSHIP BETWEEN PCSK9, ALIROCUMAB, AND LDL-C LOWERING IN FOUR PHASE 3 ODYSSEY TRIALS WITH/ WITHOUT STATIN BACKGROUND E. Stroes, T. De Bruin, M. Davidson, H. Yang, M. Kvarnstrom, T. Lundstrom (Netherlands) S. Kimura, S. Yamada, H. Noguchi, K.Y. Wang, T. Nakayama (Japan) SaG110 462 J.G. Robinson, M. Farnier, J.J. Kastelein, E.M. Roth, M.R. Taskinen, H.M. Colhoun, A. Brunet, A.T. DiCioccio, G. Lecorps, R. Pordy, M.T. Baccara-Dinet, C.P. Cannon (USA) 455 C. Yeang, M.Y. Hung, J. Pattison, K. Bowden, N. Dalton, K.L. Peterson, J.L. Witztum, S. Tsimikas, X. Que (USA) EFFICACY AND SAFETY OF EVOLOCUMAB IN PATIENTS ON HIGH- VS MODERATE-INTENSITY BACKGROUND STATIN THERAPY 461 H. Soran, A. Lira, R. Dent, I. Bridges, R. Somaratne, M. Koren (United Kingdom) 454 R. Zhetisheva, V. Naumov, L. Kovalyov, M. Kovalyova, I. Kamenihina, L. Novikova, M. Shogenova, A. Karpov (Russia) SaG108 SaG113 460 TRANSITION FROM LDL APHERESIS TO EVOLOCUMAB IN HETEROZYGOUS FH IS EQUALLY EFFECTIVE IN LOWERING LDL- BUT WITHOUT LOWERING HDL CHOLESTEROL 466 A. Hovland, K.T. Lappegård (Norway) SaG119 459 THE IMPACT OF SELECTIVE LDL APHERESIS ON SERUM ADIPOKINE LEVELS IN PATIENTS WITH HYPERCHOLESTEROLEMIA 467 V.E. Varga, H. Lőrincz, N. Zsíros, P. Fülöp, I. Seres, G. Paragh, J. Balla, M. Harangi (Hungary) I.E. Dumitriu, P. Baruah, J.C. Kaski (United Kingdom) SaG120 THE MECHANISM OF STATIN-INDUCED MODULATION OF VITAMIN D METABOLISM468 J. Beltowski (Poland) 96 97 Poster # 14:00 - 15:00Exhibition Area Vascular Biology III Chair: J. Herz (USA) SaG121 ACUTE EXPOSURE TO AIR POLLUTION AGGRAVATES ACUTE MYOCARDIAL INFARCTION AND SUBSEQUENT ISCHEMIC HEART FAILURE IN MICE 469 470 D. Wolf, T. Marchini, N. Anto Michel, D. Dürschmied, I. Hilgendorf, C. Bode, A. Zirlik (Germany) SaG122 EFFECT OF OMEGA-3 FATTY ACID SUPPLEMENTATION ON ARTERIAL ELASTICITY IN PATIETNS WITH FAMILIAL HYPERCHOLESTEROLAEMIA ON STATIN THERAPY 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria 471 D. Chan, J. Pang, P.H.R. Barrett, D.R. Sullivan, T.A. Mori, J.R. Burnett, F.M. Van Bockxmeer, G.F. Watts (Australia) SaG123 THE ABSENCE OF PCSK9 DETERMINES A LOWER NEOINTIMAL FORMATION IN RESPONSE TO PERIVASCULAR CAROTID COLLAR PLACEMENT472 N. Ferri, G. Tibolla, A. Dhyani, R. Baetta, A. Catapano, A. Corsini (Italy) SaG124 BLOOD LEVEL OF CD45+ PLATELETS AND DEVELOPMENT OF RESTENOSIS AFTER DRUG-ELUTING STENT IMPLANTATION IN PATIENTS WITH CORONARY ARTERY DISEASE 473 Z. Gabbasov, S. Kozlov, I. Melnikov, S. Byazrova, O. Saburova (Russia) SaG125 PLASMA FROM PATIENTS WITH CALCIFIED AORTIC DISEASE TRIGGERS AN OSTEOBLAST-LIKE PHENOTYPE SWITCH IN HUMAN AORTIC VALVE INTERSTITIAL CELLS 474 L. Cattan-Lévy, M.P. Jacob-Lenet, M. Dehoux, C. Deschildre, I. Codogno, M. Morvan, A.T. Gaston, G. Even, J.B. Michel, D. Messika-Zeitoun, A. Nicoletti, G. Caligiuri, J. Khallou-Laschet (France) SaG126 A NOVEL PLAYER IN VASCULAR CALCIFICATION: HYPOXIA INDUCES OSTEOGENIC DIFFERENTIATION AND EXTRACELLULAR MATRIX MINERALIZATION OF VASCULAR SMOOTH MUSCLE CELLS 475 V. Jeney, B. Enikő, T. Emese, T. Andrea (Hungary) SaG127 HH RESPONSIVE CELLS CONTRIBUTE TO VSMC ACCUMULATION FOLLOWING VASCULAR INJURY 476 P. Cahill, E. Fitzpatrick, H. Jay-Christian, S. Diana, R. Hakimjavadi, E. Redmond (Ireland) SaG128 METABOLOMIC PROFILING OF ASCENDING THORACIC AORTIC ANEURYSMS AND DISSECTIONS - IMPLICATIONS FOR PATHOPHYSIOLOGY AND BIOMARKER DISCOVERY C. Doppler, K. Arnhard, J. Dumfarth, K. Heinz, K. Danzl, B. Messner, C. Stern, D. Bernhard (Austria) 98 477 tI if h S n io t a t n e s e Poster Pr 29– Sunday, May 0 3 y a M , y a d n o M www.eas2016.kenes.com Poster Walks – Monday Board # Monday, May 30, 2016 Vascular Biology: Endothelium and Smooth Muscle Cells 001 SIGMA-1 RECEPTOR INVOLVEMENT In RHOA/ROCK ACTIVATION AND ENDOTHELIAL DYSFUNCTION INDUCED BY COCAINE 478 C.G. Saez, M.P. Hernández, K. Pereira-Flores, M. Palominos, A. LeguinaRuzzi, D. Mezzano, J. Pereira (Chile) 002 P38 MITOGEN-ACTIVATED PROTEIn KINASE IS INVOVLED In ARGINASE-IIMEDIATED ENOS-UNCOUPLING In AGING AND OBESITY 479 Y. Yu, J.P. Montani, X. Ming, Z. Yang (Switzerland) 003 SOLUBLE ENDOGLIn EFFECTS ON ENDOTHELIAL CELLS In VITRO 480 M. Varejckova, I. Nemeckova, P. Fikrova, E. Dolezelova, B. Vitverova, P. Nachtigal (Czech Republic) 004 The RhoGEF TRIO REGULATES ANGIOGENIC SPROUTING THROUGH VE-CADHERIN481 J. Kroon, I. Timmerman, M. Hoogenboezem, S.A. Van de Pavert, E.M. Weijers, P. Koolwijk, J.D. Van Buul (Netherlands) 005 IDENTIFICATION Of FLOW-SENSITIVE GENES DURING EMBRYOTIC VASCULAR DEVELOPMENT 482 C.W. Ni, N. Lawson (United Arab Emirates) 006 The NEURONAL GUIDANCE CUE SEMAPHORIn 3F IS HIGHLY EXPRESSED BY ENDOTHELIAL CELLS UPON LAMINAR FLOW AND INHIBIT MONOCYTE MIGRATION483 H. Zhang, R.G. De Bruin, W.M.P.J. Sol, E.P. Van der Veer, B.M. Van den Berg, T.J. Rabelink, A.J. Van Zonneveld, J.M. Van Gils (Netherlands) 007 SUPPLEMENTATION WITH A COMBINATION Of L-CITRULLINE AND L-ARGININE RESTORES The PLASMA L-ARGININE CONCENTRATION AND RETARDS ENDOTHELIAL SENESCENCE 484 T. Hayashi, K. Ina, M. Kuzuya (Japan) 008 FICUS DELTOIDEA ENHANCES EXPRESSION Of ENDOTHELIAL NITRIC OXIDE SYNTHASE AND REDUCES ENDOTHELIN-1 ON STIMULATED HUMAN CORONARY ARTERY ENDOTHELIAL CELLS 485 R. Ahmad, T. Rahman, N.A. Mohd Kasim, G.A. Froemming, S. Muid, N.H. Ismail, A.M. Ali, H. Nawawi (Malaysia) 009 ANTI-OXIDANT PROPERTIES Of FENUGREEK AND SAPONINS, AND THEIR EFFECTS ON eNOS EXPRESSION ON HUMAN CORONARY ARTERY ENDOTHELIAL CELLS. 486 R. Ahmad, T. Rahman, G.A. Froemming, H. Nawawi (Malaysia) 101 Poster Walks – Monday Board # Board # 010 020 ANTIOXIDANT PROPERTIES Of SAFFRON AND CROCIn AND THEIR EFFECTS ON ENDOTHELIAL NITRIC OXIDE SYNTHASE EXPRESSION In STIMULATED HUMAN CORONARY ARTERY ENDOTHELIAL CELLS 487 R. Ahmad, N.A. Mohd Kasim, T. Rahman, G.A. Froemming, H. Nawawi (Malaysia) 011 GLYCATED LDL INDUCE ENDOPLASMIC RETICULUM STRESS ALONG WITH The STIMULATION Of VCAM-1 EXPRESSION In HUMAN ENDOTHELIAL CELLS, AND The ENSUING MONOCYTE ADHESION ENDOTHELIAL CELL DEATH AND DISASSEMBLY In ATHEROSCLEROSIS 021 488 LEVOROTATORY-AMLODIPINE PLUS FLUVASTATIn CONFER ADDITIVE EFFECTS ON RETARDING ENDOTHELIUM-MESENCHYMAL TRANSITION THROUGH SUPPRESSING ROCK1 EXPRESSION 022 489 STUDIES ON The MECHANISM Of ACTION Of The ANTIPROLIFERATIVE EFFECT Of NO-DONORS FUROXANS In SMOOTH MUSCLE CELLS 023 490 The DIACYLGLYCEROL ACETYLTRANSFERASE INHIBITORS XANTHOHUMOL AND AMIDEPSINE D REVEAL LIPID SYNTHESIS AS A PROMOTER Of ANGIOGENESIS 024 491 PROLIFERATION Of ENDOTHELIAL PROGENITOR CELLS BY 11,12-EPOXYEICOSATRIENOIC ACID In I/R INJURED RAT 025 492 HIGH LEVELS Of SOLUBLE ENDOGLIn INDUCE INFLAMMATION AND OXIDATIVE STRESS In AORTA COMPENSATED WITH PRESERVED NODEPENDENT VASODILATATION MICE FED HIGH FAt DIET MEMBRANE CONTACT SITES In ENDOTHELIAL CELLS 027 ENDOTHELIAL PROGENITOR CELLS BEFORE AND AFTER TREATMENT WITH METFORMIn In PATIENTS WITH FAMILIAL COMBINED HYPERLIPIDEMIA AND INSULIn RESISTANCE C.O. Aragona, E. Imbalzano, V. Cairo, C. Conte, F. Mamone, A. Lo Gullo, M.A. Sardo, A. Saitta, G. Mandraffino (Italy) 102 The ASSESSMENT Of VARIANT DOUBLE FILTRATION PLASMAPHERESIS (DFPP) IMPACT ON The ADHESION MOLECULES CONTENT In STABLE CORONARY ARTERY DISEASE (CAD) PATIENTS AFTER CORONARY STENTING 501 028 502 The ROLE Of INHIBITORS Of WNT SIGNALING In CARDIOVASCULAR EVENTS 503 The GOOD? The BAD? The UGLY! RETINOIC ACID In MYOCARDIAL INFARCTION504 ARTERIAL STIFFNESS CORRELATES WITH EXTRACELLULAR MATRIX TURNOVER In HEART FAILURE WITH PRESERVED EJECTION FRACTION PATIENTS505 M. Martínez-Marin, J. Perez-Calvo, C. Josa-Laorden, I. Lacambra-Blasco, I. Gimenez-Lopez, J. Rubio-Gracia, V. Garces-Horna, M. Sanchez-Marteles, F. Ruiz-Laiglesia, P. Samperiz-Legarre, I. Torres-Courchoud, B. AmoresArriaga, R. Martinez-Marin, C. Sanz-Bescos, F. Roncales-Garcia Blanco (Spain) 495 029 496 The EFFECTS Of HIV-INFECTION AND ANTI-RETROVIRAL TREATMENT ON ENDOTHELIAL FUNCTION In A SOUTH AFRICAN COHORT K. Danzl (Austria) 494 A. Kivelä, V. Olkkonen (Finland) 019 500 C. Ress, A. Kirschner, M. Paulweber, K. Willeit, L. Kedenko, G. Goebel, K. Rufinatscha, K. Salzmann, G. Staudacher, H. Tilg, B. Igelseder, B. Paulweber, S. Kaser (Austria) 493 K. Jezkova, J. Rathouska, I. Nemeckova, P. Fikrova, E. Dolezelova, M. Varejckova, B. Vitverova, C. Bernabeu, J.M. Novoa, S. Chlopicki, P. Nachtigal (Czech Republic) 018 ULTRASTRUCTURAL STUDY Of ENDOTHELIUM In ADVANCED CAROTID ARTERY ATHEROSCLEROSIS N. Mashele, S. Charania, F. Essop, I. Webster, C. Westcott, N. Goswami, P. De Boever, T. Nawrot, H. Strijdom (South Africa) 026 S. Kim, J.K. Chae, J.L. Young, Y.S. Kim, S.H. Lee, S.R. Lee, K.S. Rhee, W.H. Kim, J. Ko (Republic of Korea) 017 499 M. Pyatchenkov, V. Tishko, A. Sokolov (Russia) K. Astanina, J. Spang, R.T. Hahn, D. Oster, J. Hoppstaedter, A.K. Kiemer (Germany) 016 The CAPACITY Of EL MODIFIED SERUM / APO B DEPLETED SERUM TO PROTECT VASCULAR ENDOTHELIAL FUNCTION A. Evdokimenko, T. Gulevskaya, T. Gulevskaya, S. Scrylev, V. Shchipakin, M. Tanashyan (Russia) L. Arnaboldi, M. Lombardi, M. Sinelli, B. Rolando, L. Lazzarato, R. Fruttero, A. Gasco, A. Corsini (Italy) 015 498 S. Radulović, A. Kirsch, I. Schilcher, M. Lechleitner, C. Nusshold, S. Hallström, S. Frank (Austria) A. Cai, L. Liwen, Z. Yingling, C. Jiyan, L. Xida (China) 014 UNDERSTANDING The INTERACTIVE EFFECTS Of DOXORUBICIn AND RADIOTHERAPY ON ENDOTHELIAL CELL FUNCTION - The ROLE Of JNK G. Hargrave, M. Boyd, R. Plevin (United Kingdom) S. Paone, G. Atkin-Smith, R. Tixeira, S. Caruso, L. Jiang, I. Poon, M. Hulett (Australia) 013 497 N. Grechanyk, A. Filippova, A. Kuryata (Ukraine) L. Toma, G.M. Sanda, M. Deleanu, C.S. Stancu, A.V. Sima (Romania) 012 ENDOTELIAL DYSFUNCTION, BLOOD LIPID SPECTRUM,LEVEL Of LEPTIn AND MASS Of BODY In PATIENT WITH CORONARY HEART DISEASE In COMBINATION WITH HEPATIC STEATOSIS. BYGLICAN EXPRESSION, ARTERIAL STIFFNESS AND PROATHEROGENIC PROFILE In FORMER SMOKERS AFTER 1-YEAR SMOKE CESSATION 506 G. Mandraffino, C.O. Aragona, V. Cairo, F. Mamone, A. Lo Gullo, M.A. Sardo, A. Saitta, E. Imbalzano (Italy) 103 Poster Walks – Monday Board # Board # 030 HIGH, NOT LOW LEVELS Of ENDOGENOUS ENDOSTATIn SERUM LEVELS PREDICT EVENT-FREE SURVIVAL In PATIENTS WITH PERIPHERAL ARTERIAL DISEASE507 040 B. Zierfuss, C. Herz, C. Höbaus, R. Koppensteiner, G.H. Schernthaner (Austria) 041 031 HIGH FRUCTOSE CONSUMPTION IMPAIRS AORTIC FUNCTION AND METABOLIC PARAMETERS COMPARED TO GLUCOSE In FEMALE RATS 508 042 043 HOMOARGININE: A NEW POTENTIAL AVENUE In The MANAGEMENT Of NEOINTIMAL HYPERPLASIA? 510 SOLUBLE ST2 IS A NOVEL MARKER Of AORTIC STIFFNESS AND ARTERIOSCLEROSIS MEASURED BY INVASIVE HEMODYNAMIC STUDY 044 VASCULAR RESPONSES TO INSULIn ARE IMPAIRED AFTER DIET-INDUCED OBESITY WHEREAS RESPONSES TO IGF-1 ARE MAINTAINED CARDIOMETABOLIC AND VASCULAR EFFECTS Of TREATMENT WITH A FIXED-DOSE COMBINATION ANTI-RETROVIRAL DRUG CONTAINING NUCLEOSIDE AND NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIs AND NNRTIs) In ADULT RATS 045 512 SHORT-TERM AEROBIC EXERCISE IMPROVES AORTIC STIFFNESS In WOMEN AFTER MENOPAUSE 046 513 EFFECTS Of ADIPONECTIn ON VASCULAR PROPERTIES Of CAROTID ARTERY ASSOCIATED WITH MATRIX REMODELING EFFECTS OF OXIDAZED LDL IN M2 MACROPHAGES. IMPLICATIONS IN ATHEROSCLEROSIS522 HUMAN MACROPHAGES EXPOSED TO OXIDIZED LDL OR TUNICAMYCIN EXHIBIT INCREASED MMP-9 EXPRESSION, SECRETION AND ACTIVITY BY A MECHANISM INVOLVING ENDOPLASMIC RETICULUM STRESS 523 G.M. Sanda, M. Deleanu, C.S. Stancu, M. Simionescu, A.V. Sima (Romania) 047 514 515 524 REDUCED DIETARY INTAKE OF TLR2 AND TLR4 STIMULANTS FAVOURABLY MODIFIES LIPID AND INFLAMMATORY MARKERS OF CARDIOMETABOLIC RISK IN HEALTHY MEN 525 T. Faraj, C. Erridge (United Kingdom) 049 516 RECOMBINANT DOMAIN V OF BETA(2)-GLYCOPROTEIN I INHIBITS OXLDLINDUCED TF EXPRESSION IN MACROPHAGES Y. Chi, T. Yu, Q. Liu, J. Qin, J. Li, Y. Chen, M. Li (China) 048 P. Wohlfahrt, J. Pitha, I. Kralova Lesna, O. Auzky, P. Suchanek, P. Stavek (Czech Republic) 039 521 F. Goncalves, K. Alcantara, V. Moura, P. Nolasco, J. Kalil, M. Hernandez (Brazil) H. Strijdom, N. Goswami, P. De Boever, C. Westcott, T. Ogundipe, F. Everson, A. Genis (South Africa) 038 INTIMA-MEDIA THICKNESS OF THE DESCENDING AORTA IS INFLUENCED BY AORTIC VALVE DISEASE Vascular Biology: Macrophages, Inflammation, Immunity G.K. Povlsen, I. Buza, H. Boonen, J. Worm (Denmark) 037 GENOMIC REARRANGEMENTS In HUMAN ATHEROSCLEROTIC VASCULAR TISSUES520 511 S.H. Kim, H.L. Kim, W.H. Lim, J.B. Seo, W.Y. Chung, J.H. Zo, H.L. Lee, M.A. Kim, D.G. Park, G.J. An (Republic of Korea) 036 519 J. Petrini, M. Ring, P. Eriksson, A. Franco-Cereceda, K. Caidahl, M.J. Eriksson (Sweden) F. Dellera, G.S. Ganzetti, A. Froio, S. Manzini, M. Busnelli, A. Meinitzer, G. Chiesa, C. Parolini (Italy) 035 MODIFYING The GUT MICROBIOME WITH POLYPHENOLS AND A LECTIn LIMITED DIET IMPROVES ENDOTHELIAL FUNCTION A. Sleptcov, M. Nazarenko, I. Lebedev, N. Skryabin, O. Barbarash, V. Puzyrev (Russia) I. Kvetnoi, K. Kozlov, E. Sedova, I. Bolotov, V. Polyakova (Russia) 034 518 S. Gundry (USA) MECHANICAL CONDITIONS AROUND NEOVESSELS In POPLITEAL ATHEROSCLEROTIC PLAQUES - AN ANALYSIS USING FINITE ELEMENT METHOD509 LASER CONFOCAL MICROSCOPY Of ARTERIAL WALL: ROLE Of SIGNALING MOLECULES In MECHANISMS Of RESTENOSIS The EFFECT Of HIGH-FAt DIET ON The BARRIER FUNCTIONS AND INFLAMMATORY STATUS Of HUMAN VASCULAR ENDOTHELIAL CELLS P. Gorzelak-Pabis, E. Luczak, K. Wojdan, M. Broncel, M. Chalubinski (Poland) M. Mocan, M. Bogdan, B. Sorin Nicu (Romania) 033 517 P. Risko, J. Pláteník, R. Buchal, J. Potočková, P. Kraml (Czech Republic) G. Sanguesa, M.D.M. Cascales, S. Shaligram, F. Akther, M. Baena, R. Rahimian, J.C. Laguna, M. Alegret, N. Roglans (Spain) 032 The LABILE IRON POOL AND PARAMETERS Of ARTERIAL WALL ELASTICITY THE ROLE OF OXIDIZED LOW-DENSITY LIPOPROTEINS AND AUTOANTIBODIES TO THEM IN ATHEROGENESIS IN PATIENTS WITH CORONARY ATHEROSCLEROSIS 526 M. Shogenova, A. Karpov, R. Zhetisheva, V. Masenko, V. Naumov (Russia) W.C. Tsai, Y.T. Sun (Taiwan) 104 105 Poster Walks – Monday Board # 050 CELL-SPECIFIC UPREGULATION OF APOLIPOPROTEIN E GENE EXPRESSION IN MACROPHAGES BY GLUCOCORTICOIDS Board # 060 527 V.G. Trusca, E.V. Fuior, I.M. Fenyo, I.F. Tudorache, D. Kardassis, M. Simionescu, A.V. Gafencu (Romania) 051INTERLEUKIN-27 POLYMORPHISMS ARE ASSOCIATED WITH PREMATURE CORONARY ARTERY DISEASE AND INSULIN RESISTANCE. THE GENETICS OF ATHEROSCLEROTIC DISEASE (GEA) MEXICAN STUDY ENZYMATIC DEGRADATION OF 7-KETOCHOLESTEROL (7-KC), A NEW STRATEGY FOR THE TREATMENT OF ATHEROSCLEROSIS 061 528 HUMAN MONOCYTE-DERIVED MACROPHAGES FROM CORONARY ARTERY DISEASE PATIENTS SHOW AN IMPAIRED PHENOTYPE 062 AGE-ALBUMIN REDUCES ABCA-1 CONTENT IN MACROPHAGES BY INDUCING ITS MODIFICATION BY AGE AND DEGRADATION BY THE UBIQUITIN-PROTEASOME AND LYSOSOMAL SYSTEM. 063 MONOCYTE ACTIVATION CORRELATES WITH ATHEROGENIC MITOCHONDRIAL MUTATIONS 530 064 531 065 532 066 067 PRO-INFLAMMATORY GENE EXPRESSION IN ADIPOSE TISSUE IN PATIENTS WITH ATHEROSCLEROSIS 534 068 RESPONSE GENE TO COMPLEMENT-32 REGULATES TGF-Β EXTRACELLULAR MATRIX EXPRESSION IN HUMAN AORTIC ATHEROSCLEROTIC WALL THE ROLE OF MYELOID DENDRITIC CELLS, CHEMOKINE CCL17 AND T-CELL RECEPTOR CCR4 IN ATHEROGENESIS 542 THE INFLAMMATORY PROCESS AS A RISK FACTOR OF DEVELOPING ATHEROSCLEROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS 543 MMP-12 AND TIMPS BEHAVIOUR IN STROKE RELATED TO CAROTID ARTERY STENOSIS 544 ATHEROSCLEROTIC PATIENTS HAVE M1-SKEWED MONOCYTES: COMORBIDITIES AND RISK FACTORS CONTRIBUTE 545 H. Williams, V. Patel, G. Cassorla, N. Pertsoulis, S. Li, J. Fletcher, H. Medbury (Australia) 535 069 S. Cejková, I. Králová Lesná, J. Froněk, A. Králová, R. Poledne (Czech Republic) 059 541 N. Cifani, F. Del Porto, L. Ferri, M. Proietta, D. Toni, R. Dito, M. De Michele, A. Falcou, M. Taurino (Italy) S. Kajani, M. O'Reilly, W. Guo, F. McGillicuddy (Ireland) 058 INTERMEDIATE DENSITY LIPOPROTEIN IS ASSOCIATED WITH MONOCYTE SUBSET DISTRIBUTION IN PATIENTS WITH STABLE ATHEROSCLEROSIS I. Starodubtseva (Russia) FOXO1 AND NF-κB REGULATE CYCLOOXEGENASE-2 EXPRESSION UNDER LYSOPHOSPHATIDYALCHOLINE TREATMENT IN HUMAN CARDIAC FIBROBLAST 533 DIVERGENT EFFECTS OF SODIUM SALICYLATE ON GLUCOSE METABOLISM AND REVERSE CHOLESTEROL TRANSPORT IN OBESITY 540 A. Karpov, A. Rvatcheva, M. Shogenova, R. Zhetisheva, V. Masenko, V. Naumov (Russia) H.C. Tseng, C.M. Yang (Taiwan) 057 RELATIONSHIP BETWEEN MMP-9, TIMP-1, hs CRP AND THE SEVERITY OF ATHEROSCLEROTIC CORONARY ARTERY DISEASE K. Krychtiuk, S. Kastl, T. Pongratz, G. Goliasch, L. Gaspar, G. Maurer, K. Huber, E. Dostal, S. Pfaffenberger, S. Oravec, J. Wojta, W. Speidl (Austria) A. Orekhov, N. Nikiforov, N. Elizova, M. Sazonova, A. Zhelankin, I. Sobenin (Russia) 056 EVALUATION OF MMP-7 AND TIMP-1 IN PATIENTS WITH CORONARY ATHEROSCLEROSIS539 C.R. Revnic, C. PENA, S. PRADA, F. REVNIC, G. PRADA (Romania) R. Tallada Iborra, A. Machado-Lima, U. Fabres Machado, L. Rui, E.R. Nakandakare, S. Yokoyama, M. Passarelli (Brazil) 055 538 C.R. Revnic, C. PENA, S. VOINEA, F. REVNIC, B. PALTINEANU (Romania) 529 S. Eligini, S. Fiorelli, N. Cosentino, V. Cavalca, S. Colli, G. Marenzi, E. Tremoli (Italy) 054 FEATURES OF CELLULAR AND VASCULAR INFLAMMATORY RESPONSE IN PATIENTS WITH UNSTABLE ANGINA AND MYOCARDIAL INFARCTION N. Musikhina, T. Petelina, L. Gapon, O. Irina, V. Kuznetsov (Russia) I. Perveen, S. Ahmed (Pakistan) 053 537 K. Miura, E. Saita, N. Suzuki, K. Miyata, N. Ikemura, R. Ohmori, Y. Ikegami, Y. Kishimoto, K. Kondo, Y. Momiyama (Japan) R. Posadas-Sánchez, N. Pérez-Hernández, J.M. Rodríguez-Pérez, J. Angeles-Martínez, C. Posadas-Romero, G. Cardoso-Saldaña, T. Villarreal-Molina, G. Vargas-Alarcón (Mexico) 052 THE ASSOCIATION BETWEEN PLASMA INTERLEUKIN-27 (IL-27) LEVELS AND THE SEVERITY OR INSTABLITY OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH CAD INCREASED GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) IS ASSOCCIATED WITH INFLAMMATION IN OBESE SUBJECTS 546 M. Malczewska-Malec, M. Malczewska-Malec, A. Polus, J. Goralska, U. Razny, A. Dembinska-Kiec, B. Solnica (Poland) 536 S.I. Vlaicu, A. Tatomir, D. Boodhoo, A.P. Mekala, C.A. Tegla, V. Rus, H. Rus (Romania) 106 107 Poster Walks – Monday Board # Board # 070 079 INCREASING B1A LYMPHOCYTES THROUGH APRIL OVEREXPRESSION IN APOLIPOPROTEIN E-DEFICIENT MICE STABILIZES ADVANCED ATHEROSCLEROTIC LESIONS BY DECREASING NECROTIC AREA AND INCREASING SMOOTH MUSCLE CELL CONTENT 071 CYTOMEGALOVIRUS DNA LOAD AND T-LYMPHOCYTES ACTIVATION IN ATHEROSCLEROTIC PLAQUES 080 548 A. Lebedeva, E. Nikitskaya, O. Ivanova, J.C. Grivel, E. Maryukhnich, A. Shpektor, E. Vasilieva, L. Margolis (Russia) 072 073 INTERLEUKIN-17-RELATED PATHWAYS ARE INVOLVED IN CAROTID ATHEROSCLEROSIS, BUT NOT IN STANFORD-A ACUTE AORTIC DISSECTION 549 ROLE OF T HELPER 17 LYMPHOCYTE SUBPOPOLATIONS IN CRITICAL CAROTID ARTERY STENOSIS 074 INCREASED FREQUENCIES OF CIRCULATING T-HELPERS 17 AND DIMINISHED REGULATORY T-CELLS TO T-HELPERS 17 RATIO PREDICT CAROTID ATHEROSCLEROSIS PROGRESSION 550 DECREASED BONE MARROW ACTIVITY MEASURED BY USING 18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY AMONG PATIENTS WITH CEREBRAL ARTERY ATHEROSCLEROSIS 083 551 084 085 552 086 087 554 HUMAN HERPESVIRUS ACTIVATION IN PATIENTS WITH ACUTE CORONARY SYNDROME555 E. Nikitskaya, O. Ivanova, M. Elena, G. Jean-Charles, A. Lebedeva, A. Shpektor, L. Margolis, E. Vasilieva (Russia) 108 THE LEVEL OF NITRIC OXIDE REGULATES LIPOCALIN-2 EXPRESSION UNDER INFLAMMATORY CONDITION IN RINM5F BETA-CELLS 560 DIFFERENTIAL WHITE BLOOD CELL COUNT AND METABOLIC SYNDROME IN JAPANESE MEN 561 NON-HDL CHOLESTEROL RELATES TO PRO-INFLAMMATORY STATUS OF HUMAN VISCERAL ADIPOSE TISSUE 562 EFFECT OF FAT COMPOSITION OF A MEAL ON THE ACUTE POSTPRANDIAL INFLAMMATORY RESPONSE 563 I. Shapira, O. Raz, S. Berliner (Israel) A. Dhyani, V.K. Pulakazhi Venu, P. Uboldi, A.F. Muro, A.L. Catapano, D.G. Norata (Italy) 078 559 R. Poledne, I. Kralova Lesna, A. Kralova, A. Sekerkova, J. Fronek (Czech Republic) PSORIASIS AND CORONARY ARTERY DISEASE: THE ROLE OF INFLAMMATION 553 ABSENCE OF FIBRONECTIN-EDA CONTRIBUTES TO SEPSIS OUTCOMES IN A MURINE MODEL PATIENTS WITH RHEUMATOID ARTHRITIS SHOWED ALTERED LIPOPROTEIN PROFILE WITH DYSFUNCTIONAL HIGH-DENSITY LIPOPROTEINS TO EXACERBATES INFLAMMATION AND ATHEROSCLEROTIC PROCESS Y. Ikeda, N. Hisakawa, T. Ohguro, J. Nishiuchi, Y. Kumon (Japan) P. Altieri, H.L. Banchs, J. Nieves (Puerto Rico) 077 558 S.Y. Chang, Y.H. Jo, M.J. Kim (Republic of Korea) J.M. Kim, L. Eun Seoung, P. Kwang-Yeol, S. Ju Won, J. Keun-Hwa (Republic of Korea) 076 REDOX-ACTIVE IRON IN MONOCYTES ISOLATED FROM PATIENTS WITH CHRONIC CARDIOVASCULAR DISEASE J.Y. Kim, E.Y. Lee, K.H. Cho (Republic of Korea) A. Filatova, A. Shchinova, E. Pylaeva, A. Potekhina, A. Osokina, M. Tripoten, O. Pogorelova, T. Balakhonova, E. Noeva, E. Klesareva, O. Afanasieva, T. Arefieva (Russia) 075 557 P. Kraml, P. Riško, J. Pláteník, J. Potočková (Czech Republic) 082 M. Proietta, N. Cifani, F. Del Porto, L. Ferri, G. Orgera, S. Perrotta, R. Dito, L. Tritapepe, M. Iaconi, M. Taurino (Italy) IDENTIFYING FEATURES OF VASCULAR INFLAMMATORY RESPONSE IN PATIENTS WITH MYOCARDIAL INFARCTION USING THE SYNTAX SCORE T. Petelina, N. Musikhina, L. Gapon, I. Osipova, V. Kuznetsov (Russia) 081 F. Del Porto, N. Cifani, L. Ferri, S. Perrotta, R. Dito, M. Iaconi, R. Carletti, M. Proietta, L. Tritapepe, C. Di Gioia, M. Taurino (Italy) 556 A. Van Dam, S. Bekkering, M. Crasborn, L. Van Beek, S. Van den Berg, F. Vrieling, S. Joosten, V. Van Harmelen, M. De Winther, E. Lutgens, M. Boon, N. Riksen, P. Rensen, J. Berbée (Netherlands) 547 K.H. Zheng, S. Bernelot Moens, S.I. Van Leuven, S. Havik, D. Baeten, E. Stroes (Netherlands) BACILLE-CALMETTE-GUÉRIN LOWERS PLASMA CHOLESTEROL AND DELAYS ATHEROSCLEROTIC LESION PROGRESSION IN MICE THE RELATIONSHIP BETWEEN HELICOBACTER PYLORI INFECTION AND ARTERIAL STIFFNESS IN ADULTS WITH ABNORMAL GASTRIC ENDOSCOPIC FINDINGS564 K.C. Park, M.J. Kim, K.S. Park, Y.S. Kim, H.C. Cho, H.R. Sung, K.H. Park, B.H. Choi, K.C. Kim (Republic of Korea) 088 PROTECTIVE EFFECT OF CAROTENOIDS ON CX40 AD CX43 EXPRESSION IN THE LEFT VENTRICLE OF NORMOTENSIVE WISTAR RATS AFTER ADMINISTRATION OF LPS 565 K. Frimmel, J. Krizak, B. Liptak, J. Navarova, V. Knezl, E. Breierova, I. Bernatova, L. Okruhlicova (Slovakia) 109 Poster Walks – Monday Board # Board # Vascular Biology: Myocardial Infarction, Stroke, Peripheral Vascular Disease 099 089 EFFECT OF THROMBOLYTIC THERAPY AND PERCUTANEOUS CORONARY INTERVENTION (PCI) ON INFLAMMATORY MEDIATORS 566 EFFECT OF ENDOVASCULAR TREATMENT AT PATIENTS WITH EARLY POSTINFARCTION STENOCARDIA 100 101 567 TERMS OF SUCCESS OF REHABILITATION IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS568 P. Bondarenko, A. Novikova, M. Ivanov, M. Ermina, M. Chvostova, A. Yadernaya, R. Al-Banna (Russia) 092 INTERSECTED GENES IN HYPERLIPIDEMIA AND CORONARY BYPASS PATIENTS: FEASIBLE BIOMARKERS FOR CORONARY HEART DISEASE 093 MYOCARDIAL STANNING AFTER THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL INFARCTION. 102 EARLIEST OUTCOMES OF ACUTE CORONARY SYNDROME IN PATIENTS WITH TYPE 2 DIABETES 103 570 N-ACETYLCYSTEINE IN A COMBINATION THERAPY REDUCES MYOCARDIAL DAMAGE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND IMPROVES LEFT VENTRICULAR FUNCTION AFTER PERCUTANEOUS CORONARY INTERVENTION. 104 571 RELATIONSHIP BETWEEN LIPID DISORDERS AND SEVERITY AND NATURE OF CORONARY ARTERY LESIONS IN MALE PATIENTS WITH CORONARY ARTERY DISEASE 105 572 PHYSIOLOGICAL AND BIOCHEMICAL PARAMETERS OF HYPERTHYROID RAT HEART DURING ISCHEMIA REPERFUSION 106 573 ACUTE ARTERIAL OCCLUSION OF APPARENTLY HEALTHY ARTERIES - A CONCLUSIVE EXPLANATION USING FRACTAL PHYSICS D. Tesloianu, M. Agop, I. Nedelciuc (Romania) 110 ATHEROSCLEROTIC SOFT PLAQUE REGRESSION USING TRANSCUTANEOUS LOW-LEVEL COMBINED DUAL-FREQUENCY SONICATION ACCOMPANIED BY HIGH-DOSE ATORVASTATIN AND PESDA MICROBUBBLES ADMINISTRATION 580 INDIVIDUAL ATORVASTATIN DOSES TITRATION TO TREATMENT OF CAROTID PLAQUES IN PATIENTS WITH ARTERIAL HYPERTENSION I-II DEGREE 581 EFFECT OF SHORT-TERM INTENSIVE ROSUVASTATIN THERAPY ON CAROTID ATHEROSCLEROTIC PLAQUE VOLUME IN VERY HIGH CARDIOVASCULAR RISK PATIENTS USING THE THREE-DIMENSIONAL ULTRASOUND582 PLEIOTROPIC EFFECTS OF ANTI-ATHEROSCREROTIC CILOSTAZOL ON BRAIN OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS (SHR-SP) 583 K. Abe, Y. Omote, T. Yamashita, R. Morihara, Y. Nakano, Y. Ohta (Japan) 107 574 C.R. Revnic, C. PENA, F. REVNIC, A.S. NICA, S. PRADA, G. PRADA (Romania) 098 579 Z. Luginova, M. Koshurnikova, E. Solovieva, T. Balakhonova, A. Susekov (Russia) V. Kashtalap, O. Barbarash, O. Hryachkova, A. Novitskaya (Russia) 097 CORRELATION OF HIGH-SENSITIVE CRP, CAROTID INTIMA-MEDIA THICKNESS, AND THE CHRONIC KIDNEY DISEASE OF HEALTHY RESIDENTS: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY (KOPS) N. Balashenka, V. Podpalov (Belarus) A. Nizomov, B. Toshev, M. Mukhamedova, J. Berdiqulov (Uzbekistan) 096 578 H. Mehrad, M. Mokhtari-Dizaji, H. Ghanaati (Iran) S. Abdijalilova, M. Kenjaev, L. Botirova, U. Ganiyev, A. Nizomov (Uzbekistan) 095 ASSOCIATION OF BASELINE APOLIPOPROTEIN B AND FRIEDEWALD LDLC WITH LONG-TERM RE-INFARCTION IN HYPERTRIGLYCERIDEMIC PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION Y. Tanaka, M. Shimizu, N. Furusyo, Y. Kato, J. Hayashi (Japan) M. Kenjaev, S. Kenjaev, S. Abdijalilova, A. Nizomov (Uzbekistan) 094 577 M. Hermans, A. Van der Laarse, M. Schalij, F. Romijn, N. Smit, Y. Van der Burgt, W. Jukema, C. Cobbaert (Netherlands) 569 Y. Maneerat, K. Prasongsukarn, S. Benjathummarak, W. Dechkhajorn, U. Chaisri (Thailand) VENOUS THROMBOEMBOLISM AND CORONARY SYNDROME A. Babets, A. KURIATA (Ukraine) S. Salakhitdinov, M. Kenjaev, S. Abdijalilova, A. Nizomov (Uzbekistan) 091 576 P. Sudjana, F. Nugraha, C. Achmad, A. Purnomowati, T. Aprami (Indonesia) B. Bagheri, A. Garjani, B. Taherkhanchi, B. Sohrabi, F. Mousavi (Iran) 090 AUTOLYSIS IN CAD STEMI ANTEROSEPTOAPICOLATERAL WALL PATIENT, A CASE REPORT ASSOCIATION BETWEEN VO2PEAK AND CLAUDICATION WALKING TIME MEASURED DURING WALKING ON A TREADMILL AND IN COMMUNITY SETTINGS OUTDOOR WALK - PILOT STUDY 584 E. Rosłoniec, A. Kulik, J. Trzeciak, P. Mika (Poland) 575 108 EFFECTS OF NORDIC POLE WALKING ON OXIDATIVE STRESS AND WALKING ABILITIES IN PATIENTS WITH INTERMITTENT CLAUDICATION 585 E. Rosłoniec, M. Więcek, M. Bawelski, M. Maciejczyk, J. Głodzik, P. Mika (Poland) 111 Poster Walks – Monday Board # Board # 109 120 LOW NUMBER OF CIRCULATING CD34 POSITIVE CELL IS ASSOCIATED WITH GREATER PROGRESSION OF CORONARY CALCIUM DETERMINED BY MDCT586 T. Miyoshi, M. Doi, K. Nakamura, H. Ito (Japan) 110 A GIANT LEFT ATRIUM 121 587 ARTERIAL STIFFNESS AS A PREDICTOR OF RECOVERY OF LEFT VENTRICULAR SYSTOLIC FUNCTION AFTER ACUTE MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION588 EVALUATION OF CHANGES OF GLOBAL LONGITUDINAL STRAIN IN PATIENTS WITH STEMI AFTER MYOCARDIAL REVASCULARIZATION ASSESSMENT OF EFFICIENT REVASCULARIZATION ON DYNAMICS OF VELOCITY PARAMETERS IN PATIENTS WITH STEMI 122 589 STRUCTURAL AND FUNCTIONAL PROPERTIES OF THE MAJOR ARTERIES IN PATIENTS WITH CORONARY HEART DISEASE AND HEALTHY SUBJECTS 124 590 LIVER DYSFUNCTION AND 18F-NAF ATHEROSCLEROTIC PLAQUE UPTAKE - ANALYSIS IN HIGH-CARDIOVASCULAR RISK INDIVIDUALS 591 125 THE RELATIONSHIP BETWEEEN CALCIFIED PLAQUES AND RESTENOSIS AFTER CAROTID ENDARTERECTOMY 126 ASSOCIATION BETWEEN SERUM ZINC LEVEL AND CAROTID ATHEROSCLEROSIS WITHOUT PLAQUE 127 594 M. Park (Republic of Korea) 118 PLAQUE CHARACTERISATION AND ANALYSIS IN THE RISK STRATIFYING PATIENTS WITH SYMPTOMATIC CAROTIS STENOSIS AREA MEASUREMENT OF CAROTID PLAQUE COMPARING B-MODE, DOPPLER COLOR AND CONTRAST-ENHANCED ULTRASOUND IMAGING E. Nyman, D. Vanoli, C. Grönlund, U. Näslund, P. Lindqvist (Sweden) 112 601 LIMITATIONS OF CONTRAST-ENHANCED ULTRASOUND WITH EVALUATION OF NEOVASCULARISATION IN THE ATHEROSCLEROTIC PLAQUE 602 COMPARISON OF THE RESULTS OF CORONARY ANGIOGRAPHY AND PARAMETERS OF LOCAL RIGIDITY OF COMMON CAROTID ARTERY IN PATIENTS WITH CORONARY HEART DISEASE 603 EFFICACY OF SCREENING OF SUBCLINICAL AORTAL ATHEROSCLEROSIS IN WORKING-AGE POPULATION DEPENDING ON INVESTIGATIONAL METHODS.604 N. Koziolova, A. Chernyavina (Russia) 128 595 SUBCLINICAL CAROTID AND CEREBRAL ATHEROSCLEROSIS SCREENING IN WORKING-AGE POPULATION: EFFICACY OF DIFFERENT INVESTIGATIONAL METHODS. 605 N. Koziolova, A. Chernyavina (Russia) D. Vanoli, P. Lindqvist (Sweden) 119 NON-INVASIVE HIGH-FREQUENCY ULTRASOUND USING INTIMA AND INTIMA/MEDIA THICKNESS RATIO (BUT NOT CIMT), CORRECTLY MONITORED EXPECTED BENEFICIAL VASCULAR EFFECTS OF MENOPAUSAL HORMONE THERAPY V. Oleynikov, L. Salyamova, A. Khromova, N. Burko (Russia) 593 H. Katano, K. Yamada, M. Mase (Japan) 117 600 A. Evdokimenko, L. Druina, A. Chechetkin, M. Tanashyan, T. Gulevskaya, S. Scrylev (Russia) 592 M. Santos, M. Castelo-Branco, R. Silva, A. Gomes, P. Donato, J. Ferreira, C. Domingues, M. Pego, L. Gonçalves, M.J. Ferreira (Portugal) 116 INVESTIGATION OF PROTOPORPHYRIN IX-MEDIATED SONODYNAMIC THERAPY ON INTERMEDIATE STAGE ATHEROSCLEROSIS USING A NEW COMPUTERIZED B- MODE ULTRASOUND ANALYZING METHOD T. Naessen, M. Larsson (Sweden) V. Oleynikov, A. Khromova, L. Salyamova (Russia) 115 599 H. Mehrad, M. Farhoudi (Iran) V. Oleynikov, V. Galimskaya, E. Romanovskaya, I. Avdeeva (Russia) 114 REFERENCE VALUES FOR LOCAL ONE-POINT CAROTID STIFFNESS BY ECHO-TRACKING IN A LARGE POPULATION OF HEALTHY SUBJECTS S. Favretto, S. Carerj, J. Jaroch, K. Łoboz-Grudzień, F. Antonini-Canterin, C. Zito, E. Bossone, M. PIrisi, O. Vriz (Italy) 123 V. Oleynikov, V. Galimskaya, E. Romanovskaya (Russia) 113 QUANTIFICATION OF MICROVESSELS DENSITY IN CAROTID PLAQUE BY CONTRAST-ENHANCED ULTRASOUND WITH HISTOPATHOLOGIC VALIDATION598 A. Evdokimenko, L. Druina, A. Chechetkin, S. Scrylev, T. Gulevskaya, M. Tanashyan (Russia) G. Mandraffino, C.O. Aragona, S. Quartuccio, G. Trapani, A. Saitta, M. Vatrano, E. Imbalzano (Italy) 112 597 B. Muinjonov, E. Giyazitdinova (Uzbekistan) Y. Saleh, A. Almaghraby, B. Hammad, M. Elbahey, A. Samoka, A. Ghoneem, M. Seleem (Egypt) 111 DO STROKE PATIENTS WITH NORMAL CAROTID ARTERIES REQUIRE TEE FOR EXCLUSION OF RELEVANT AORTIC PLAQUE? 129 596 RETINAL VASCULAR CALIBER, OCULAR BLOOD FLOW AND ENDOTHELIN-1 LEVEL IN BLOOD SERUM IN PATIENTS WITH SUBCLINICAL ATHEROSCLEROSIS606 N. Adzhemian, V. Neroev, T. Kiseleva, M. Ezhov, N. Balatskaya, N. Ilina, V. Tankovskiy (Russia) 113 Poster Walks – Monday Board # Board # 130 139 INVESTIGATING THE FEASIBILITY OF B-MODE ULTRASONOGRAPHY ACCOMPANIED BY PESDA MICROBUBBLES ADMINISTRATION FOR ACCURATE VISUALIZATION OF INTRAPLAQUE NEOVASCULARIZATION 607 SUBCLINICAL ATHEROSCLEROSIS AND COGNITIVE IMPAIRMENT IN UZBEKISTAN608 140 D. Akramova, A. Umarov (Uzbekistan) 132 THE RELATIONSHIP BETWEEN NONALCOHOLIC HEPATIC STEATOSIS AND CAROTID ATHEROSCLEROSIS AT THE ELDERLY 133 141 RELATIONSHIP BETWEEN THE CHOLESTEROL AND TRIGLYCERIDE CONTENT OF LIPOPROTEIN SUBCLASSES AND CAROTID INTIMA MEDIA THICKNESS: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY610 CONFOCAL DUAL-PULSED ELECTROHYDRAULIC SHOCK WAVE THERAPY ACCOMPANIED BY PESDA MICROBUBBLES AND ATORVASTATIN ADMINISTRATION REDUCE THE ATHEROSCLEROTIC INTRAPLAQUE NEOVESSELS IN THE RABBIT CAROTID ARTERY 611 142 RISK FACTORS OF ATHEROSCLEROSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS WITH THYROID GLAND LESION 144 612 CARDIOVASCULAR MORTALITY AND MORBIDITY IN A GROUP OF PATIENTS WITH HIV DIAGNOSIS 145 613 ARE CARDIOVASCULAR RISK FACTORS THE NEW THREAT TO HIV PATIENTS? M. Monsalvo, E. Sifuentes Diaz, A. Caceres Gestoso, P. Perez Guerrero, I. Tinoco Racero, A. De los Santos Moreno (Spain) 114 DEVELOPMENT OF A NOVEL HOMOGENEOUS ASSAY FOR REMNANT LIPOPROTEINS620 MOST OF THE HEPATIC TRIGLYCERIDE LIPASE (HTGL) IS BOUND TO APOE-RICH HDL IN POST-HEPARIN PLASMA 621 NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM 622 V. Sachdev, C. Leopold, R. Bauer, J.V. Patankar, J. Iqbal, S. Obrowsky, M. Doktorova, M. Goeritzer, B. Scheicher, D. Kolb, G. Hoefler, A.V. Turnbull, A. Zimmer, M.M. Hussain, A.K. Groen, D. Kratky (Austria) 614 146 THE ROLE OF ANGPTL3 IN HUMAN LIPOPROTEIN METABOLISM 623 A. Tikka, J. Metso, M. Jauhiainen (Finland) E. Sifuentes Diaz, M. Monsalvo Hernando, C. Palomar Muñoz, N. Caro Gomez, E. Lopez Tinoco, R. Toro (Spain) 138 619 K. Nakajima, S. Usui, R. Shinohata, K. Miyashita, S. Imamura, J. Kobayashi, T. Machida, H. Sumino, M. Murakami (Japan) R. Sayfutdinov, O. Bugrova, K. Nagornova, M. Dobrolubov, N. Artemova (Russia) 137 ARTERIAL STIFFNESS IN A BLACK SOUTH AFRICAN COHORT INFECTED WITH THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) N. Satoh, M. Ikaida, Y. Ito (Japan) E. Berta, M. Harangi, V.E. Varga, H. Lőrincz, I. Seres, E.V. Nagy, G. Paragh, M. Bodor (Hungary) 136 618 Lipoproteins and Lipid Metabolism: ApoB Containing Lipoproteins 143 Vascular Biology: Immune Disease and Cardiovascular Pathologies EVALUATION OF SERUM CHEMERIN LEVEL IN PATIENTS WITH HASHIMOTO’S THYROIDITIS PREVALENCE OF INCREASED ARTERIAL STIFFNESS AND PERIPHERAL ARTERIAL DISEASE IN PATIENTS WITH SYSTEMIC SCLEROSIS C.M. Fourie, J.M. Van Rooyen, H.W. Huisman, C.M. Mels, W. Smith, R. Kruger, S. Botha, L. Lammertyn, L. Gafane, A.E. Schutte (South Africa) H. Mehrad, S.A. Seyedikhosroshahi (Iran) 135 617 K. Tziomalos, I. Gkougkourelas, A. Sarantopoulos, E. Bekiari, N. Raptis, E. Makri, K. Tselios, M. Pantoura, A. Hatzitolios, P. Boura (Greece) N. Furusyo, M. Shimizu, Y. Kato, Y. Tanaka, J. Hayashi (Japan) 134 PREVALENCE OF INCREASED ARTERIAL STIFFNESS AND PERIPHERAL ARTERIAL DISEASE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS K. Tziomalos, I. Gkougkourelas, A. Sarantopoulos, E. Bekiari, E. Makri, N. Raptis, K. Tselios, M. Pantoura, A. Hatzitolios, P. Boura (Greece) 609 A. Capisizu, A. Zamfirescu, R. Dascalescu, O. Stanciu, S.M. Aurelian (Romania) 616 A. Baragetti, M. Magnoni, K. Garlaschelli, L. Grigore, M. Berteotti, I. Scotti, E. Bozzolo, A. Berti, A.A. Manfredi, E. Ammirati, A.L. Catapano, G.D. Norata (Italy) H. Mehrad, M. Mokhtari-Dizaji, H. Ghanaati (Iran) 131 SYSTEMIC LUPUS ERYTHEMATOSUS FLARE-UP IS ASSOCIATED WITH INCREASED 5-YEARS CAROTID INTIMA-MEDIA THICKNESS PROGRESSION 147 615 ASSOCIATION OF THE POSTPRANDIAL CHYLOMICRON TRIGLYCERIDE/ ApoB INDEX AND CARDIOVASCULAR EVENTS 624 H. Scharnagl, C. Werner, T. Stojakovic, W. März, U. Laufs (Austria) 115 Poster Walks – Monday Board # 148 SYSTEMATIC ASSAY OF LIPOPROTEIN LIPASE ACTIVITY AND MASS IN COHORT OF PATIENTS WITH HISTORY OF TYPE V HYPERLIPIDEMIA Board # 158 625 O. Marmontel, M. Di Filippo, S. Nony, C. Marcais, C. Caussy, S. Charriere, A. Sassolas, P. Moulin (France) 149 159 APOLIPOPROTEIN C-III GLYCOFORMS CORRELATE HETEROGENEOUSLY WITH PLASMA LIPID PROFILE IN SUBJECTS WITH CORONARY ARTERY DISEASE626 160 PLASMA APOLIPOPROTEIN CIII LEVELS AND INCIDENT CORONARY ARTERY DISEASE RISK: THE EPIC-NORFOLK PROSPECTIVE POPULATION STUDY.627 14C MIRISTIC ACID AND 3H CHOLESTEROL UPTAKE STUDIES IN AGING RABBIT AORTA AND HEART MUSCLE.THE IMPACT OF SERUM FACTORS FROM PATIENTS WITH LIPID METABOLIC DISORDERS LDL SUBFRACTIONAL ANALYSIS: A LABORATORY DIAGNOSTIC ASSAY IN PATIENTS WITH CAROTID AND CORONARY ATHEROSCLEROSIS 161 THERMAL STABILITY OF HUMAN PLASMA LDL(-): A PARADOXICAL BEHAVIOR OF LDL AGGREGATION 162 LIPOPROTEINS FROM CORD BLOOD OF SMALL BABY FOR GESTATIONAL AGE SHOWED ELEVATED TRIGLYCERIDE AND DIMINISHED APOA-I CONTENT WITH MORE PRO-ATHEROSCLEROTIC AND PROINFLAMMATORY ACTIVITY 163 629 630 POLOXAMERS INHIBIT ASSOCIATION OF MULTIPLY MODIFIED LDL, BUT DO NOT REDUCE THEIR ATHEROGENIC POTENTIAL MULTIPLE MODIFICATION OF LDL CIRCULATING IN BLOOD OF ATHEROSCLEROTIC PATIENTS COMPARABILITY STUDY OF CANDIDATE REFERENCE METHODS FOR LDL-P MEASUREMENTS N. Clouet Foraison, S. Vaslin-Reimann, C. Cobbaert, P. Gillery, V. Delatour (France) 116 639 SUBFRACTIONAL DISTRIBUTION OF APO B-CONTAINING LIPOPROTEINS: A NEW MARKER FOR DETECTION OF INDIVIDUAL CARDIOVASCULAR RISK 640 Lipoproteins and Lipid Metabolism: Lipoprotein Metabolism 631 165 NOVEL CHIMERAS PROVIDE INSIGHT INTO STRUCTURE/FUNCTION ACTIVITY IN APOLIPOPROTEIN E3 AND APOLIPOPROTEIN AI 641 632 166 633 642 EFFECTS OF ROSUVASTATIN ON GENE EXPRESSION OF LIVER LDL-R, PCSK9, SREBP-2, AND LRP1 IN OVARIECTOMIZED RATS SUBMITTED OR NOT TO VOLUNTARY EXERCISE 643 J.M. Lavoie, E.T. Ngo Sock, G. Mayer (Canada) 167 634 EFFECTS OF TUMOR BEARING ON SERUM AND LIVER LIPID LEVELS IN SATO LUNG CARCINOMA (SLC)-IMPLANTED RATS: EFFECT OF A DIFFERENCE IN IMPLANTED CELL NUMBERS M. Kawasaki (Japan) A. Orekhov, I. Sobenin, A. Melnichenko (Russia) 157 LIPIDOMICS OF PLASMA, LIVER AND AORTA OF PCSK9-KO MICE V. Narayanaswami, M. Lek, N. Ibe, W. Beck, J. Bielicki, P. Weers (USA) A. Melnichenko, N. Elizova, A. Orekhov (Russia) 156 OXIDIZED LOW-DENSITY LIPOPROTEINS AND LECTIN-LIKE OXIDIZED LDL RECEPTOR-1 ARE POSITIVELY ASSOCIATED TO PCSK9 IN TYPE 2 DIABETES MELLITUS638 V. Metelskaya, I. Ozerova, N. Gavrilova, E. Yarovaya, S. Boytsov (Russia) 164 S.M. Kim, C. Kyung-Hyun (Republic of Korea) 155 637 G. Chiesa, M. Busnelli, C. Parolini, S. Manzini, G.S. Ganzetti, F. Dellera, M. Suoniemi, M. Hilvo, R. Hurme, K. Ekroos, C.R. Sirtori, R. Laaksonen (Italy) 628 A. Rull, S. Jayaraman, A. Rivas, M. Pérez Cuellar, J. Ordóñez Llanos, J.L. Sánchez Quesada, O. Gursky (Spain) 154 STRUCTURAL CHANGES INDUCED BY ACIDIC PH IN HUMAN APOLIPOPROTEIN B-100 Y. Nekaies, B. Baudin, S. Kalbousi, M. Sakly, N. Attia (France) N. Gavrilova, V. Metelskaya, I. Ozerova, E. Yarovaya, S. Boytsov (Russia) 153 636 A. Benito-Vicente, J.A. Fernández-Higuero, J.C.G. Milicua, A. Etxebarria, H. Ostolaza, J.L.R. Arrondo, C. Martin (Spain) C.R. Revnic, C. Pena, F. Revnic, S. Voinea, B. Paltineanu (Romania) 152 ADIPONECTIN AS A BLOCKER OF OXIDIZED LDL A. Kakino, Y. Fujita, T. Sawamura (Japan) J. Van Capelleveen, S.J. Bernelot Moens, X. Yang, N.T. Wareham, K.T. Khaw, E.S.G. Stroes, J.L. Witztum, G.K. Hovingh, S.M. Boekholdt, S. Tsimikas (Netherlands) 151 635 L. Cibickova, R. Gasko, H. Vaverkova, D. Karasek (Czech Republic) C. Chiariello, A. Castagna, N. Martinelli, P. Guarini, M. Manfredi, E. Ranzato, S. Martinotti, E. Marengo, D. Cecconi, O. Olivieri (Italy) 150 THE DETERMINATION OF APOLIPOPROTEIN B BY CALCULATION AND BY MEASUREMENT ON SET OF DYSLIPIDEMIC PATIENTS BLOOD LEVELS OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) IN MEN OF DIFFERENT POPULATION SUBGROUPS AND ITS RELATIONSHIP WITH UNFAVORABLE LONG-TERM PROGNOSIS 644 K. Astrakova, Y. Ragino, E. Shakhtshneider, S. Astrakov, M. Voevoda (Russia) 117 Poster Walks – Monday Board # 168 LDL RECEPTOR (LDLR) EXPRESSION AND FUNCTION IN HUMAN PANCREATIC BETA CELLS Board # 179 645 A. Thedrez, R. Scharfmann, P. Parnet, E. Nobécourt, G. Lambert (France) 169 170 HIGH INTAKE OF SODIUM CHLORIDE EXACERBATES DEGRADATION OF HUMAN LIPOPROTEINS AND IMPAIRMENT OF REPRODUCTIVE CAPACITY VIA TESTICULAR TOXICITY IN ZEBRAFISH 646 180 E.Y. Lee, K.H. Cho (Republic of Korea) SPHINGOMYELIN CONTENT OF ERYTHROCYTE MEMBRANES IS IN LINEAR ASSOCIATION WITH MEMBRANES’ LOADING WITH CHOLESTEROL IN CORONARY ARTERY DISEASE PATIENTS. MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN THE ISCHEMIC HEART 647 G. Chalikias, P. Kikas, I. Drosos, M. Pavlaki, A. Thomaidis, S. Konstantinides, D. Tziakas (Greece) 181 STABLE ISOTOPE KINETIC STUDY OF APOLIPOPROTEIN M IN HEALTHY SUBJECTS648 M. Croyal, M. Chétiveaux, K. Ouguerram, S. Billon-Crossouard, E. Nobécourt, M. Krempf (France) 172 HEPATOSTEATOSIS AND ESTROGEN INCREASE APOLIPOPROTEIN O PRODUCTION IN THE CHICKEN NORMALIZATION OF LIPOPROTEIN PROFILE DURING PREGNANCY IN LCAT DEFICIENCY 182 649 CHARGED RESIDUES IN THE C-TERMINAL DOMAIN OF APOLIPOPROTEIN A-I MEDIATE OLIGOMERIZATION 183 650 EFFECTS OF APOE VARIANTS ON PLTP INTERACTION AND ACTIVATION OF LOW AND HIGH ACTIVITY FORMS OF PLTP 184 651 HIGH-PERFORMANCE GEL PERMEATION CHROMATOGRAPHY ANALYSIS DEMONSTRATES ATHEROGENIC PROPERTIES OF LIPOPROTEINS IN PATIENTS WITH CHOLESTERYL ESTER TRANSFER PROTEIN DEFICIENCY 652 COMPARISON OF FATTY ACID COMPOSITION OF SUBCUTANEOUS, PERICARDIAL AND EPICARDIAL ADIPOSE TISSUE AND ATRIAL TISSUE IN PATIENTS WITH HEART DISEASE 653 660 EFFECT OF SALSALATE ON METABOLIC SYNDROME-RELATED PARAMETERS AND ACTIVITY OF BROWN ADIPOSE TISSUE IN WISTAR AND HEREDITARY HYPERTRIGLYCERIDEMIC RATS 661 185 SPECIFIC CIRCULATING PHOSPHOLIPIDS, ACYLCARNITINES, AMINO ACIDS AND BIOGENIC AMINES ARE AEROBIC EXERCISE MARKERS 662 186 HETEROGENEITY OF PLASMA LOW DENSITY LIPOPROTEINS AND HIGH DENSITY LIPOPROTEINS: SOME GENDER PECULIARITIES IN SUBFRACTIONAL DISTRIBUTION 663 V. Metelskaya, I. Ozerova, N. Gavrilova, S. Boytsov (Russia) 654 R. Bülow Eschen, J. Gu, J.J. Andreasen, A. Andreasen, S. LundbyeChristensen, E. Berg Schmidt (Denmark) 178 INVESTIGATION OF LPL INDEPENDENT PATHWAYS OF TG-RICH LIPOPROTEIN METABOLISM IN LPL DEFICIENCY T. Felder, S. Ring-Dimitriou, S. Auer, S. Soyal, L. Kedenko, M. Rinnerthaler, J. Cadamuro, E. Haschke-Becher, E. Aigner, B. Paulweber, W. Patsch (Austria) T. Okada, T. Ohama, M. Okazaki, H. Matsuda, M. Sairyo, Y. Zhu, R. Kawase, D. Masuda, M. Koseki, M. Nishida, Y. Sakata, S. Yamashita (Japan) 177 659 V. Skop, J. Trnovska, M. Huttl, H. Malinska, I. Markova, O. Oliyarnyk, L. Kazdova (Czech Republic) M. Jauhiainen, I. Dafnis, J. Metso, V. Zannis, A. Chroni (Finland) 176 ATHEROGENIC INDEX OF PLASMA FOR PREDICTION OF FUTURE CARDIOVASCULAR DISEASE IN PREDIABETES AND DIABETES POPULATION D. Gaudet, D. Brisson, K. Tremblay (Canada) P. Weers, V. Narayanaswami, L. Fuentes, J. Horn, R. Ellena, K. Cong (USA) 175 658 P. Regmi, B. Baral, M. Raut, M.P. Khanal (Nepal) A. Ossoli, E. Hanna, S. Simonelli, R. Mullan, S. Chamney, J. Chestnutt, F. Stewart, G. Franceschini, L. Calabresi (Italy) 174 COMPLEX PHOSPHOLIPIDS ASSOCIATE WITH ARTERIAL NOREPINEPHRINE, NON-ESTERIFIED FATTY ACIDS AND HEART RATE, MARKERS OF SYMPATHETIC NERVE SYSTEM IN METABOLIC SYNDROME SUBJECTS INDEPENDENTLY OF INSULIN RESISTANCE 657 P. Nestel, N. Straznicky, A. Anwar, M. Pyush, P. Meikle (Australia) B. Schmidinger, A. Weijler, W.J. Schneider, M. Hermann (Austria) 173 656 G. Speziali, D. Cecconi, N. Martinelli, O. Olivieri, A. Castagna, P. Guarini (Italy) M. Klevstig, M. Scharin Täng, M. Ståhlman, M. Levin, J. Borén (Sweden) 171 MYRISTIC ACID PLASMA LEVELS ARE STRONGLY CORRELATED WITH TRIGLYCERIDE AND APOLIPOPROTEIN C-III PLASMA CONCENTRATION IN A COHORT OF SUBJECTS WITH OR WITHOUT CORONARY ARTERY DISEASE 187 IDENTIFICATION OF A NOVEL LXR TARGET 664 E.C.L. Cook, J.K. Nelson, V. Sorrentino, N. Zelcer (The Netherlands) DIETARY SATURATED FATTY ACIDS AGGRAVATE PRESSURE OVERLOADINDUCED CARDIOMYOPATHY IN MICE IN THE ABSENCE OF CARDIAC STEATOSIS 655 I. Muthuramu, R. Amin, N. Singh, A. Postnov, O. Gheysens, P. Van Veldhoven, B. De Geest (Belgium) 118 119 Poster Walks – Monday Board # Board # Lipoproteins and Lipid Metabolism: Lp(a) 197 188 PROGNOSTIC VALUE OF COMBINED LIPOPROTEIN(A) AND HOMOCYSTEINE IN ANGIOGRAPHICALLY PROVEN PATIENTS WITH CORONARY ARTERY DISEASE 665 S.W. Kwon, H.M. Kwon (Republic of Korea) 189 LIPOPROTEIN(A) MEASUREMENT AND ASSOCIATION WITH MEDICAL HISTORY IN SECONDARY CARE LIPID CLINICS ELEVATED LIPOPROTEIN(A) AND ISCHEMIC STROKES- A CASE REPORT 198 666 667 199 RATIONALE AND DESIGN OF A CLINICAL TRIAL TO ASSESS LP(A) LOWERING WITH IONIS-APO(A)-LRX IN PATIENTS UNDERGOING APHERESIS FOR ELEVATED LP(A) AND RECURRENT CARDIOVASCULAR EVENTS668 PREVALENCE OF LPA SINGLE NUCLEOTIDE POLYMORPHISMS AND ISOFORMS IN PATIENTS ENROLLED IN A PHASE 2 IONIS-APO(a)Rx CLINICAL TRIAL NATURAL TEMPORAL VARIABILITY IN Lp(a) LEVELS IN PATIENTS ENROLLED IN THE PLACEBO ARMS OF IONIS-APO(a)Rx ANTISENSE OLIGONUCLEOTIDE CLINICAL TRIALS 200 201 669 202 670 PROGNOSTIC VALUE OF SERUM LIPOPROTEIN(A) LEVELS ON LONGTERM MORTALITY IN A LARGE SAMPLE OF SUBJECTS IN PRIMARY CARDIOVASCULAR PREVENTION: DATA FROM THE BRISIGHELLA HEART STUDY671 A SYSTEMATIC REVIEW AND META-ANALYSIS COMPARING THE EFFECTS OF STATINS AND FIBRATES ON PLASMA LIPOPROTEIN(A) LEVELS 203 DEFINING THE MECHANISM OF LIPOPROTEIN(A) [LP(A)] LOWERING BY ALIROCUMAB IN TRANSGENIC MOUSE MODELS C. Yeang, P. Miu, S. Green, X. Yang, M.Y. Hung, J.L. Witztum, S. Tsimikas (USA) THE ROLE OF Lp(a) LEVELS AND APOPROTEIN(a) PHENOTYPE IN THE DEVELOPMENT OF ATHEROSCLEROSIS IN PATIENTS WITH CORONARY ARTERY DISEASE 678 LIPOPROTEIN(a) AND T-HELPER CELLS AS INDEPENDENT PREDICTORS OF RAPID PROGRESSION OF CAROTID ATHEROSCLEROSIS 679 POPULATION AND ASSAY THRESHOLDS FOR THE PREDICTIVE VALUE OF LIPOPROTEIN(A) FOR RISK OF CORONARY ARTERY DISEASE: THE EPICNORFOLK PROSPECTIVE POPULATION STUDY 680 R. Verbeek, S.M. Boekholdt, R.M. Stoekenbroek, G.K. Hovingh, J.L. Witztum, N.J. Wareham, M.S. Sandhu, K.T. Khaw, S. Tsimikas (Netherlands) 204 672 A. Sahebkar, L.E. Simental-Mendía, M. Banach, M.C. Serban, G.F. Watts (Iran) 196 677 O. Afanasieva, E. Pylaeva, T. Arefieva, E. Klesareva, M. Afanasieva, A. Potekhina, A. Shchinova, T. Balakhonova, O. Pogorelova, M. Tripoten, S. Pokrovsky (Russia) F. Fogacci, S. D'Addato, A.F.G. Cicero, E. Bertagnin, S. Palmisano, L. D'Agostini, E. Grandi, M. Giovannini, C. Borghi (Italy) 195 CIRCULATING LIPOPROTEIN (A) [LP(A)] LEVELS AND RISK OF CARDIOVASCULAR DISEASE: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY D. Labudovic, K. Toseska-Trajkovska, S. Alabakovska, J. Bogdanska, S. Jovanova (FYR Macedonia) N.J. Viney, S. Marcovina, J. Tami, S. Xia, J.L. Witztum, S. Tsimikas (USA) 194 676 R. Hoogeveen, W. Sun, V. Salim, B. Christie (USA) E.S. Stroes, F.M. Van der Valk, D. Gaudet, I. Gouni-Berthold, N.P. Riksen, E. Steinhagen-Thiessen, B. Isermann, B. Nordestgaard, N.J. Viney, S. Marcovina, S.G. Hughes, J. Tami, S. Xia, J.L. Witztum, S. Tsimikas (Netherlands) 193 A NOVEL MODIFIED LIPID TETRAD INDEX AS PREDICTOR OF PREMATURE CORONARY ARTERY DISEASE IN INDIANS S. Das (India) P.M. Moriarty, E.S. Thiessen, J.L. Witztum, N.J. Viney, S. Tsimikas (USA) 192 LIPOPROTEIN(a) AND INSULIN RESISTANCE: A POSSIBLE INVERSE RELATIONSHIP BETWEEN TWO WELL-KNOWN CARDIOVASCULAR RISK FACTORS675 C.O. Aragona, E. Imbalzano, V. Cairo, F. Mamone, A. Lo Gullo, M.A. Sardo, A. Saitta, G. Mandraffino (Italy) P. Moriarty, N. Sehar, L. Denney, F. Perez-Marques, A. Panchal, P. Luna (USA) 191 674 C. Yeang, S. Tsimikas (USA) K.E. Shipman, A.J. Lawson, W. Alkaaby, A.F. Jones, R. Cramb (United Kingdom) 190 LIPOPROTEIN(A)-CHOLESTEROL (LP(A)-C) LEVELS DETERMINED BY VERTICAL AUTO PROFILE (VAP) CORRELATES WEAKLY WITH LP(A) MASS BUT MODESTLY WITH HDL-C: IMPLICATIONS FOR APPROPRIATE INTERPRETATION OF CLINICAL DATA STATUS OF INFLAMMATION, ENDOTHELIAL ACTIVATION AND PROTHROMBOGENESIS AMONG NEGRITOS AND MALAYS WITH METABOLIC SYNDROME 681 S.S. Mokhtar, N.A. Mohd Mokhsin, F. Mohd Nor, S.A. Shaari, H. Nawawi, B.P. Hoh, T. Rahman (Malaysia) 673 205 ELEVATED LIPOPROTEIN(A) LEVELS RESULT IN A HIGH CARDIOVASCULAR RISK – A PROSPECTIVE ANALYSIS OF A LIPIDOLOGY OUTPATIENTS UNIT 682 U. Schatz, S. Fischer, U. Julius, S.R. Bornstein, S. Tselmin (Germany) 120 121 Poster Walks – Monday Board # 206 PROFILE OF CIRCULATING miRNAs IN PATIENT WITH HIGH Lp(a) TREATED BY LDL/Lp(a) APHERESIS Board # 215 683 D. Dlouha, J. Pitha, Z. Eretova, O. Viklicky, A. Parikova (Czech Republic) 207 FAMILIAL HYPERCHOLESTEROLEMIA (FH) WITH ELEVATED LIPOPROTEIN(a) (Lp(a)) LEVELS AND AGGRESSIVE CORONARY HEART DISEASE: A CASUISTIC APPROACH LIPOPROTEIN(a) IS A PREDICTOR OF ONE-YEAR VEIN GRAFT OCCLUSIONS IN STABLE ANGINA PATIENTS RECEIVED LIPOPROTEIN APHERESIS FOR REFRACTORY HYPERCHOLESTEROLEMIA AFTER CORONARY ARTERY BYPASS GRAFTING 216 684 217 685 LIPOPROTEIN(A) LEVEL AS A PREDICTOR OF LONG-TERM CARDIOVASCULAR OUTCOMES AFTER PERCUTANEOUS CORONARY INTERVENTIONS686 EFFECT OF NIACIN ON LIPOPROTEIN SUBFRACTIONS CONCENTRATION IN PATIENTS WITH ELEVATED LIPOPROTEIN(a) 218 219 687 220 APOA-I DEPLETION IN CHOW-FED APOEKO MICE SEVERELY WORSENS CORONARY ATHEROSCLEROSIS DEVELOPMENT 688 221 EVALUATION OF NOVEL APOA-I TWO-SITE IMMUNOASSAYS 689 690 222 J. Lövgren, P. Negi, T. Heikkilä, T. Tallgren, K. Pettersson, M. Jauhiainen, U. Lamminmäki (Finland) 214 EICOSAPENTAENOIC ACID (EPA) MEMBRANE INCORPORATION REDUCES ABCA1-DEPENDENT CHOLESTEROL EFFLUX IN UNLOADED AS WELL AS IN CHOLESTEROL-LOADED PRIMARY HUMAN MACROPHAGES THROUGH DIFFERENT MECHANISMS ELEVATED LEVELS OF LECITHIN:CHOLESTEROL ACYLTRANSFERASE (LCAT) ARE ASSOCIATED WITH REDUCED ATHEROMA BURDEN – AN IVUS STUDY 696 EVALUATION OF HDL CHOLESTEROL EFFLUX CAPACITY (CEC) AFTER CONSUMPTION OF AN INNOVATIVE PASTA ENRICHED WITH BIOACTIVE COMPONENTS AND FUNCTIONAL PROBIOTICS 697 AEROBIC EXERCISE TRAINING DOES NOT SYSTEMATICALLY AFFECT MACROPHAGE GENE EXPRESSION INVOLVED IN REVERSE CHOLESTEROL TRANSPORT AND CHOLESTEROL EFFLUX IN CETP TRANSGENIC MICE 698 P.R. Pinto, K.S. Silva, D.J. Gomes, A. Machado-Lima, R.T. Iborra, G.S. Ferreira, E.C.R. Quintao, E.R. Nakandakare, U.F. Machado, M.L.C. Corrêa-Giannella, S. Catanozi, M. Passarelli (Brazil) G.S. Ganzetti, M. Busnelli, C. Parolini, S. Manzini, F. Dellera, C.R. Sirtori, G. Chiesa (Italy) 213 695 E. Cipollari, F. Zimetti, M.P. Adorni, N. Ronda, D. Angelino, N. Pellegrini, F. Bernini, E. Favari (Italy) S. Filou, E. Karavia, C. Constantinou, E. Zvintzou, K. Kypreos (Greece) 212 IDENTIFICATION OF A NOVEL UPREGULATOR OF ABCA1 AND SRB1 EXPRESSION WITH THE ACTION OF REGULATING CHOLESTEROL METABOLISM IN VITRO AND IN VIVO D. Rhainds, C. Gebhard, M. Cossette, M.C. Guertin, E. Rhéaume, J.C. Tardif (Canada) Lipoproteins and Lipid Metabolism: HDL FUNCTIONAL DIFFERENCES BETWEEN APOLIPOPROTEIN E- AND APOLIPOPROTEIN A-I- CONTAINING HDL PARTICLES 694 S. Si, Y. Xu, C. Liu, P. Liu, X. Wang, B. Hong (China) E. Utkina, O. Afanasieva, N. Artemieva, M. Ezhov, I. Adamova, Y. Berestetskaya, S. Pokrovsky (Russia) 211 INFLAMMATION POTENTLY SUPPRESSES ABCA1-MEDIATED CHOLESTEROL EFFLUX FROM MACROPHAGES, AND NOT ADIPOCYTES, VIA ACTIVATION OF JAK/STAT PATHWAY M. O'Reilly, M. Goodwin, O. Ansmidte, H. Roche, F. McGillicuddy (Ireland) M. Mitroshkin, M. Ezhov, M. Safarova, O. Afanasieva, Y. Matchin, S. Pokrovsky (Russia) 210 PROBUCOL OXIDIZED PRODUCTS, SPIROQUINONE AND DIPHENOQUINONE, PROMOTE REVERSE CHOLESTEROL TRANSPORT IN MICE693 K. Shiotani, E. Yakushiji, M. Ayaori, T. Nishida, S. Takiguchi, H. Uto-Kondo, M. Sasaki, M. Yogo, T. Komatsu, R. Lu, S. Yokoyama, K. Ikewaki (Japan) R. Adzhiev, M. Ezhov, O. Afanasieva, S. Pokrovsky (Russia) 209 692 D. Greco, L. Mele, A. Piemontese, S. Battista, A. Poli, F. Bernini, I. Zanotti (Italy) A. Dybvig, A. Græsdal (Norway) 208 EFFECTS OF MODERATE AND EXCESS ALCOHOL CONSUMPTION ON THE REVERSE CHOLESTEROL TRANSPORT IN VIVO HDL CHOLESTEROL EFFLUX IS NOT PREDICTIVE OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS ON HEMODIALYSIS 699 C. Kopecky, S. Ebtehaj, B. Genser, C. Wanner, M.D. Saemann, U. Tietge (Austria) 223 691 XANTHOHUMOL, A PRENYLATED FLAVONOID IN HOPS, PROMOTES MACROPHAGE REVERSE CHOLESTEROL TRANSPORT IN HAMSTER 700 H. Hirata, H. Uto-Kondo, M. Ogura, M. Ayaori, K. Ikewaki (Japan) N. Fournier, S. Tardivel, B. Vedie, J.F. Benoist, F. Allaoui, J.L. Paul (France) 122 123 Poster Walks – Monday Board # Board # 224 234 FAT-ACTIVATED ER STRESS INDUCES THE REDUCTION OF ABCG5/8 EXPRESSION IN THE SMALL INTESTINE AND LIVER OF HYPERLIPIDEMIC HAMSTERS AND THE APPEARANCE OF DYSFUNCTIONAL HDL 701 C.S. Stancu, M.G. Carnuta, G.M. Sanda, L. Toma, M. Deleanu, L.S. Niculescu, M. Simionescu, A.V. Sima (Romania) 225 ASSOCIATIONS BETWEEN LIPID SUBFRACTIONS AND SERUM MYELOPEROXIDASE LEVELS IN UNTREATED HYPERLIPIDEMIC PATIENTS 226 ASSOCIATION OF HIGH-DENSITY LIPOPROTEIN SUBCLASSES WITH CAROTID INTIMA-MEDIA THICKNESS:SHIMANE CoHRE STUDY 702 227 HIGH DENSITY LIPOPROTEINS EXERT PRO-INFLAMMATORY EFFECTS ON MACROPHAGES VIA PASSIVE CHOLESTEROL DEPLETION AND PKC-NF-KB/ STAT1-IRF1 SIGNALING 703 228 RELATIONSHIP BETWEEN FRAMINGHAM SCORE, HDL-CHOLESTEROL AND C-REACTIVE PROTEIN AT ELDERLY PATIENTS 704 THE LIPID FRACTIONS AS RISK FACTORS FOR ATHEROSCLEROSIS IN DIFFERENT AGE GROUPS IN BOSNIAN POPULATION 238 METRICS OF HIGH-DENSITY LIPOPROTEIN FUNCTION AND HOSPITAL MORTALITY IN ACUTE HEART FAILURE PATIENTS 705 239 706 CAUSAL LINK BETWEEN SERUM AMYLOID A AND OXIDATIVE DAMAGES TO HIGH-DENSITY LIPOPROTEIN 707 240 241 708 HIGH-DENSITY LIPOPROTEIN (HDL) FUNCTION AND SUBCLASS DISTRIBUTION IN OBESE AND NORMAL-WEIGHT BLACK AND WHITE AFRICAN WOMEN. 715 STATUS OF INFLAMMATION AND ENDOTHELIAL ACTIVATION IN SUBJECTS WITH LOW HIGH DENSITY LIPOPROTEIN CHOLESTEROL AMONG ABORIGINES IN MALAYSIA 716 EFFECT OF STATINS ON HDL IN FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS717 242 710 HDL AS A CRUCIAL INDICATOR OF AN EARLY CLINICAL MANIFESTATION OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA718 S. Urazgildeeva, M.V. Muzalevskaya, A.V. Tregubov, T.V. Nekrasova, V.S. Gurevich (Russia) INFLUENCE OF HDL-CHOLESTEROL LEVELS ON HDL PARTICLES LIPID COMPOSITION IN HEALTHY INDIVIDUALS. AN NMR-BASED LIPIDOMIC STUDY 709 C. Kostara, V. Tsimihodimos, E. Bairaktari, M. Elisaf (Greece) 233 VITAMIN D STATUS AND HDL FUNCTIONALITY IN HEALTHY PREMENOPAUSAL WOMEN M. Licona-Rashid, R. Yahya, D. Wattimena, J. Roeters van Lennep, C. Christoffersen, E. Sijbrands, A. Verhoeven, M. Mulder (Netherlands) S. Jayaraman, C. Haupt, O. Gursky (USA) 232 A PHASE III MULTICENTRE, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY (TANGO) TO EVALUATE CER-001 ON CAROTID ATHEROSCLEROSIS (VESSEL WALL AREA) IN PATIENTS WITH FAMILIAL PRIMARY HYPOALPHALIPOPROTEINAEMIA714 N.A. Mohd Mokhsin, W.N.H. Wan Ahmad, F.H. Sakri, N.A. Mohd Kasim, N. Mohd Nasir, S. Abdul Razak, M. Md Yasin, A. Mohd Ismail, T. Rahman, H. Nawawi (Malaysia) I. Potočnjak, V. Degoricija, M. Trbušić, S. Dokoza Terešak, B. Radulović, G. Pregartner, B. Andrea, B. Tiran, G. Marsche, S. Frank (Austria) 231 713 F. Zimetti, D. Kocyigit, D. Greco, M.P. Adorni, N. Ronda, K.M. Gurses, S.H. Oguz, A. Gurlek, L. Tokgozoglu (Italy) B. Pojskic, E. Stimjanin, L. Pojskic, H. Selimovic, A. Macic-Dzankovic, S. Palo, I. Sisic (Bosnia and Herzegovina) 230 HDL-SPHINGOMYELIN REDUCTION AFTER WEIGHT LOSS BY AN ENERGY-RESTRICTED DIET IS ASSOCIATED WITH THE IMPROVEMENT OF METABOLIC SYNDROME COMPONENTS IN OVERWEIGHT PATIENTS E. Stroes, R. Benghozi, J.L. Dasseux, J. Genest, H. Ginsberg, C. Keyserling, E. Leitersdorf, P. Raggi, A. Von Eckardstein (Netherlands) S. Opris, G. Constantin, M. Grigorie (Romania) 229 712 O. Pérez-Méndez, M. Martínez-Ramírez, M. Madero (Mexico) 237 E. Van der Vorst, K. Theodorou, Y. Wu, M. Hoeksema, P. Goossens, C. Bursill, L. Huitema, S. Tas, M. Gijbels, K. McDaniels, C.C. Wang, M. Leitges, T. Lawrence, L. Touqui, J. Plat, M. Van Eck, K.A. Rye, M. De Winther, E. Biessen, M. Donners (Germany) ESTIMATION OF HDL ANTIOXIDATIVE ACTIVITY IN SUBJECTS WITH ACUTE CORONARY SYNDROME H. Thakkar, V. Vincent, A. Roy, S. Singh, L. Ramakrishnan, A. Singh (India) 236 Y. Notsu, T. Nabika, S. Yano, A. Nagai (Japan) 711 L. Persègol, M. Darabi, C. Dauteuille, M. Lhomme, R. Salvayre, A. NègreSalvayre, S. Monier, A. Kontush (France) 235 A. Szentpéteri, H. Lőrincz, N. Zsíros, V.E. Varga, I. Seres, M. Katkó, P. Fülöp, G. Paragh, M. Harangi (Hungary) SMALL, DENSE HDL DISPLAY POTENT VASORELAXING ACTIVITY, REFLECTING THEIR ELEVATED CONTENT OF S1P ENDOTHELIAL PROTECTIVE PROPERTIES OF HDL IMPROVE EARLY AFTER ROUX-EN-Y GASTRIC BYPASS BUT NOT AFTER DIET-INDUCED WEIGHT LOSS: THE SUPERIOR CARDIOMETABOLIC BENEFITS OF RYGB 719 E. Osto, E. McLoughlin, P. Doytcheva, M. Charakida, L. Van Gaal, J. Deanfield, T. Lüscher (Switzerland) N. Woudberg, J. Goedecke, D. Blackhurst, M. Frias, R. James, L. Opie, S. Lecour (South Africa) 124 125 Poster Walks – Monday Board # Board # 243 253 EFFECTS OF BARIATRIC SURGERY ON HIGH-DENSITY LIPOPROTEIN SUBTYPES720 G. Rega-Kaun, C. Kaun, E. Dostal, S. Oravec, M. Prager, J. Wojta, W. Speidl (Austria) 244 INTERLEUKIN-6 REDUCES PARAOXONASE-1 ACTIVITY IN A DOSEDEPENDENT MANNER; EVIDENCE FOR A POTENTIAL NOVEL LIPOPROTEIN-BASED MODULATORY MECHANISM TERMINALIA ARJUNA MODULATES LIPID EFFLUX AND INFLAMMATION IN HYPERCHOLESTEROLEMIC RABBITS 730 J. Frutuoso, M. Bourbon (Portugal) 254 CORONARY ARTERY DISEASE AS A RISK FOR DEVELOPING TYPE 2 DIABETES MELLITUS 731 C. Saely, A. Vonbank, P. Rein, D. Zanolin, A. Leiherer, A. Muendlein, H. Drexel (Austria) 721 A. Abedpour Dehkordi, H. Nayeri, G.A. Naderi, N. Jafari Dinani, M. Boshtam (Iran) 245 THE NEED TO CREATE AWARENESS TOWARDS CHOLESTEROL 255 722 V. Dhawan, R. Rather, D. Trikha (India) C-REACTIVE PROTEIN SIGNIFICANTLY PREDICTS CARDIOVASCULAR EVENTS BOTH IN PERIPHERAL ARTERIAL DISEASE PATIENTS WITH AND IN PERIPHERAL ARTERIAL DISEASE PATIENTS WITHOUT THE METABOLIC SYNDROME732 A. Vonbank, C. Saely, P. Rein, D. Zanolin, A. Leiherer, H. Drexel (Austria) 256 CVD Risk Factors 246 ELEVATED NEUTROPHILS, MONOCYTES AND WHITE CELL COUNTS IN PATIENTS WITH MYOCARDIAL INFARCTION COMPARED WITH STABLE CORONARY ARTERY DISEASE THE RISK FACTORS OF ATHEROSCLEROSIS IN ROMA POPULATION IN SOUTH BOHEMIA 723 257 724 258 RISK OF DEMENTIA HOSPITALISATION ASSOCIATED WITH CARDIOVASCULAR RISK FACTORS IN MIDLIFE AND OLDER AGE: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY 259 PULSE WAVE VELOCITY IS CORRELATED WITH THE SERUM N-TERMINAL FRAGMENT OF BRAIN NATRIURETIC PEPTIDE LEVEL INDEPENDENTLY OF CENTRAL BLOOD PRESSURE AND THE AUGMENTATION INDEX 726 260 ATHEROSCLEROTIC LESIONS OF AORTO-ILIAC SEGMENT AND LONGTERM CONSEQUENCES OF RECONSTRUCTIVE OPERATIONS 261 727 COMBINED EFFECTS OF ADIPONECTIN AND VISCERAL FAT ON THE RISK OF METABOLIC SYNDROME THE EFFECT OF MOXONIDINE ON LIPID PROFILE OF PATIENTS WITH ARTERIAL HYPERTENSION, GRADE 1 AND 2 736 RISK OF INCIDENT HYPERTENSION ACCORDING TO METABOLIC HEALTH AND OBESITY: DEFINITION OF METABOLIC HEALTH DOES NOT MATTER 737 BRACHIAL-ANKLE PULSE WAVE VELOCITY IS ASSOCIATED WITH COMPOSITE CAROTID AND CORONARY ATHEROSCLEROSIS IN A MIDDLEAGED ASYMPTOMATIC POPULATION 738 H.J. Joo, S.A. Cho, J.Y. Cho, S. Lee, J.H. Park, S.H. Hwang, S.J. Hong, C.W. Yu, D.S. Lim (Republic of Korea) 728 A. Kozireva, M. Ivanov, P. Bondarenko, M. Ermina, D. Kozhevnikov, P. Puzdriak, A. Yadernaya, A. Kebryakov (Russia) 252 735 C.H. Jung, W.J. Lee, J.Y. Park, C.Y. Park, S. Kim (Republic of Korea) M. Shimizu, N. Furusyo, Y. Kato, Y. Tanaka, J. Hayashi (Japan) 251 AGE-DEPENDENCE OF THE MAGNITUDE OF LIPID PROFILE VARIABLES RESEMBLANCE BETWEEN FIRST DEGREE RELATIVES IN FAMILIES OF PATIENTS WITH EARLY CORONARY HEART DISEASE E. Karlafti, A. Hatzitolios, T. Didangelos, M. Baltatzi, G. Koliakos, A. Kalkavouri, E. Liorda, V. Chasiotis, C. Savopoulos (Greece) B. Muinjonov, E. Giyazitdinova (Uzbekistan) 250 734 M. Konnov, A. Deev, N. Gratsiansky (Russia) LIPOPROTEIN PHENOTYPE IN NAïVE PATIENTS WITH KLINEFELTER SYNDROME725 A. Antonucci, A. Bonaldo, P. Scarinzi, M. Barichello, P. Bigolin, N. Caretta, M. Ghezzi, R. Selice, M. Terrin, D. Vianello, R. Marin, A. Ferlin, C. Foresta, E. Manzato, F. Fabris, S. Bertocco, S. Zambon, A. Zambon (Italy) 249 OVERWEIGHT IN CHILDREN OF PATIENTS WITH EARLY CORONARY HEART DISEASE: RELATION TO OWN AND PARENTAL CHARACTERISTICS` M. Konnov, A. Deev (Russia) V. Adamkova, J. Hubacek, D. Novakova, V. Adamek, V. Lanska, V. Tothova (Czech Republic) 248 733 A. Vonbank, C. Saely, P. Rein, D. Zanolin, A. Leiherer, H. Drexel (Austria) I. Trakarnwijitr, B. Li, H. Adams, J. Layland, J. Garlick, A. Wilson (Australia) 247 PRO B-TYPE NATRIURETIC PEPTIDE SIGNIFICANTLY PREDICTS FUTURE VASCULAR EVENTS IN PERIPHERAL ARTERIAL DISEASE PATIENTS WITH TYPE 2 DIABETES 729 262 SUSTAINED METABOLIC SYNDROME AFTER LIFESTYLE COUNSELING WAS ASSOCIATED WITH HIGHER RISK OF SUBCLINICAL CORONARY ATHEROSCLEROSIS739 H.J. Joo, S.A. Cho, J.Y. Cho, S. Lee, J.H. Park, S.H. Hwang, S.J. Hong, C.W. Yu, K.J. An, D.S. Lim (Republic of Korea) K.H. Ha, D.J. Kim, H.C. Kim (Republic of Korea) 126 127 Poster Walks – Monday Board # Board # 263 274 ASSOCIATION OF Pro12Ala PPARγ AND -308G/A TNFα WITH PPARγ AND TNFα mRNA LEVELS IN VISCERAL ABDOMINAL TISSUE IN FERTILE WOMEN IN RUSSIA 264 CAN NON-CHOLESTEROL STEROLS AND LIPOPROTEIN SUBCLASSES DISTRIBUTION PREDICT DIFFERENT PATTERNS OF CHOLESTEROL METABOLISM AND STATIN THERAPY RESPONSE? 275 SERUM LIPID PROFILE ON ADMISSION FOR ISCHEMIC STROKE/ TRANSIENT ISCHEMIC ATTACK 741 276 DETERMINATION OF FACTORS CONTRIBUTING TO ATHEROSCLEROTIC DISEASE PROGRESSION IN PATIENTS WITH SYMPTOMATIC PERIPHERAL ARTERIAL DISEASE (PAD) 277 742 COMPLIANCE INITIATIVES IN MANAGEMENT OF PATIENTS WITH CORONARY ARTERY DISEASE AND PARKINSONISM SYNDROME 743 HEART RATE TURBULENCE AS A MORTALITY PREDICTOR IN 5 YEARS STUDY IN PATIENTS WITH CRORONARY HEART DISEASE 279 744 EFFECTS OF ASTHMA SEVERITY ON CHANGE OF PRESSURE OF PULMONARY ARTERY IN PATIENTS WITH ARTERIAL HYPERTENSION 280 745 CLINICAL CHARACTERISTICS OF PATIENTS ON HEMODIALYSIS WITH PERIPHERAL ARTERIAL DISEASE 281 746 ASSOCIATIONS BETWEEN OSTEOPOROSIS AND SIGNIFICANT CORONARY ARTERY DISEASE IN ASYMPTOMATIC POSTMENOPAUSAL WOMEN 747 282 ADJUSTED NECK CIRCUMFERENCE AND METABOLIC SYNDROME: RESULTS FROM THE BRISIGHELLA HEART STUDY 748 283 NON-CORONARY ATHEROSCLEROSIS PREVALENCE ACCORDING TO THE DATA OF THE ADULT POPULATION SCREENING SERUM ENDOSTATIN IS CORRELATED TO RENAL FUNCTION INDEPENDENTLY OF CAROTID ATHEROSCLEROSIS: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY (KOPS) 756 SYSTEMATIC REVIEW OF HERPES ZOSTER AND ITS ASSOCIATION WITH CARDIOVASCULAR EVENTS 757 EXPOSURE TO CARDIOVASCULAR DISEASE RISK FACTORS IN CHILDHOOD IS ASSOCIATED WITH INCREASED CAROTID EXTRA MEDIAL THICKNESS IN ADULTHOOD: THE CHILDHOOD DETERMINANTS OF ADULT HEALTH STUDY 758 CANDIDATE GENE POLYMORPHISMS RELATED TO LIPID AND CARBOHYDRATE METABOLISM SHOW AN ASSOCIATION WITH RISK FACTOR COMPONENTS OF THE METABOLIC SYNDROME IN ASIAN INDIANS. 759 284 750 CLINICAL CHARACTERISTICS AND LDL-CHOLESTEROL MANAGEMENT IN PATIENTS WITH CARDIOVASCULAR EVENT AND/OR DIABETES IN THE NETHERLANDS760 E. Heintjes, J. Kuiper, B. Lucius, F. Penning-van Beest, L. Kutikova, A. Liem, R. Herings (Switzerland) 749 E. Bertagnin, S. D'Addato, F. Fogacci, S. Palmisano, L. D’Agostini, A.F.G. Cicero, M. Giovannini, M. Rosticci, C. Borghi (Italy) 273 755 T. Maistry (South Africa) S.N. Lee (Republic of Korea) 272 THE ASSOCIATION OF AN ELEVATED SERUM ENDOSTATIN LEVEL AND CAROTID ATHEROSCLEROSIS: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY (KOPS) H. West, M. Skilton, B. Fraser, T. Dwyer, A. Venn, C. Magnussen (Australia) N. Aoyama (Japan) 271 754 N. Erskine, H. Tran, L. Levin, C. Ulbricht, R. Goldberg (USA) A. Odegova, E. Tarlovskaya (Russia) 270 ACCURATE CARDIOVASCULAR EVENT RISK ESTIMATION CAN BE OBTAINED USING CORONARY ARTERY SCAN Y. Kato, M. Shimizu, N. Furusyo, Y. Tanaka, J. Hayashi (Japan) N. Zagidullin, D. Gareeva, I. Lackman, I. Sagitov, S. Zagidullin (Russia) 269 753 Y. Kato, M. Shimizu, N. Furusyo, Y. Tanaka, J. Hayashi (Japan) A. Shalaeva, N. Dadabaeva, M. Bozorboev, G. Kasimdjanova (Uzbekistan) 268 CHADS2 AND CHA2DS2-VASC SCORES PREDICT CARDIOVASCULAR DISEASE IN STATIN-TREATED INDIVIDUALS WITHOUT ATRIAL FIBRILLATION M. Gracia, D. Craiem, A. Simon (Spain) 278 L.P. Zielinski, M.M. Chowdhury, B.P. Worsfold, S.C. Harrison, J.R. Boyle, P.D. Hayes, P.A. Coughlin (United Kingdom) 267 752 F. Barkas, E. Klouras, G. Liamis, M. Elisaf, E. Liberopoulos (Greece) T. Vassalo, F. Faria, T. Duarte, I. Colaço, D. Cruz, J.L. Ducla Soares (Portugal) 266 PREVALENCE OF RISK FACTORS AND CARDIOVASCULAR DISEASES IN EMPLOYEES OF A SINGLE PLANT IN DIFFERENT AGE GROUPS R. Allanov, R. Rakhimov, E. Shalaeva, N. Dadabaeva (Uzbekistan) T. Gojković, S. Vladimirov, V. Spasojević-Kalimanovska, A. Zeljković, J. Vekić, D. Kalimanovska-Oštrić, Z. Jelić-Ivanović (Serbia) 265 751 S. Lee, Y.S. Lee, B. Kim (Republic of Korea) 740 A. Kopytova, T. Usenko, V. Miroshnikova, E. Bazhenova, M. Nikolaev, A. Panteleeva, I. Semenova, A. Neimark, E. Baranova, S. Pchelina (Russia) EPICARDIAL FAT THICKNESS IS ASSOCIATED WITH HIGHER VAGAL TONE WAIST-HIP-RATIO AND 1-YEAR CLINICAL OUTCOME IN PATIENTS WITH NON-ST-ELEVATION ACUTE CORONARY SYNDROME 761 H.W. Lee, T.J. Hong, J.H. Choi, B.W. Kim (Republic of Korea) R. Khokhlov, L. Tribuntseva, V. Burlachuk, L. Khokhlov (Russia) 128 129 Poster Walks – Monday Board # Board # 285 295 GLOMERULAR FILTRATION RATE (GFR) MODERATES THE PROTECTIVE EFFECT OF MEDITERRANEAN DIET AGAINST CARDIOVASCULAR INCIDENCE: 10-YEAR FOLLOW-UP (2002-12) OF THE ATTICA STUDY 762 E. Georgousopoulou, C. Pitsavos, D. Panagiotakos, C. Chrysohoou, I. Skoumas, M. Chatzigeorgiou, D. Tousoulis, C. Stefanadis (Greece) 286 PLAQUE CHARACTERIZATION AND REMODELING BY CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND CORONARY EVENTS DURATION OF DIABETES IS AN INDEPENDENT DETERMINANT AND INTERACTED WITH GENDER FOR ACUTE MYOCARDIAL INFARCTION 296 763 PRESENCE OF CAROTID PLAQUES AND CARDIOVASCULAR DISEASE EVENTS: A PROSPECTIVE STUDY 297 764 298 TWO-GENERATION CARDIOVASCULAR DISEASE PREVALENCE IN FAMILIAL HYPERCHOLESTEROLEMIA766 R. Mateo-Gallego, S. Perez-Calahorra, M. Laclaustra, N. Plana, C. Lahoz, J. Pedro-Botet, J.F. Ascaso, A. Vila Belmonte, P. Valdivielso, A. Brea, F. Civeira (Spain) 290 RAPID RISE IN PREVALENCE OF HYPERTENSION IN YOUNG IN NATIONAL CAPITAL REGION (NCR) OF DELHI, INDIA VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL, BLOOD PRESSURE, AND HEART RATE: THE GAIN IN CONTEXT OF CIRCUMSTANCES IMPROVING CARDIOVASCULAR PREVENTION IN PATIENTS WITH HIGH CARDIOVASCULAR RISK THROUGH AN INNOVATIVE APPROACH: “THE COACHING” CARE MODEL OVERWEIGHT/OBESITY AND CORONARY HEART DISEASE: AGE DEPENDENCIES IN METABOLIC MEDIATION DECREASED SERUM LEVELS OF SOLUBLE DIPEPTIDYL PEPTIDASE IV ARE ASSOCIATED WITH ALL-CAUSE DEATH IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE M.T. Howanietz, C.T. Herz, C. Höbaus, R. Koppensteiner, G.H. Schernthaner (Austria) 130 RHEUMATOID ARTHRITIS AND ATHEROSCLEROSIS: WHY IS IMPORTANT TO EVALUATE THIS? 775 COMPARISON OF COMBINED THERAPY OF CAD ACCOMPANIED BY GASTRODUODENAL PATHOLOGY 776 768 777 HIGH PREVALENCE OF CVD RISK FACTORS AND UNSATISFACTORY CONTROL OF LDL-C LEVELS IN 40-YEARS-OLD MEN AND 50-YEARS-OLD WOMEN IN THE CZECH REPUBLIC 778 Z. Chmelik, M. Vrablík (Czech Republic) 302 769 PLASMA METHIONINE IS NOT ASSOCIATED WITH RISK OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH SUSPECTED STABLE ANGINA PECTORIS 779 I. Dhar, V. Lysne, P. Ueland, A. McCann, O. Nygård (Norway) 303 THE DIFFERENCE IN BLOOD PRESSURE READINGS BETWEEN ARMS AND CARDIOVASCULAR RISK: AN URBANITE INDIAN STUDY 780 P. Bhasin, S. Kapoor (India) 770 304 771 INCREASED VISCERAL FAT AND LOWER MUSCLE STRENGTH ASSOCIATED WITH ACUTE MYOCARDIAL INFARCTION E. Okuyan, B. Ayca, S. Varol (Turkey) 301 J. Fritz, S. Strohmaier, G. Nagel, H. Concin, H. Ulmer (Austria) 294 299 767 S. Mosteoru, K. Kotseva, O.C. Cosor, L. Gaita, R. Pleava, A. Dumitrescu, G. Mut-Vitcu, D. Gaita, S. Mancas, D. Wood (Romania) 293 774 M. Parvu, S. Coman, S. Voidazan (Romania) 300 E. Pello, T. Kouznetsova, Y. Nikitin, J. Staessen (Russia) 292 KLOTHO GENE POLYMORPHISMS ARE ASSOCIATED WITH PROGRESSION OF ATHEROMATOSIS IN PATIENTS WITH CKD. RESULTS OF TWO YEARS FOLLOW-UP OF THE NEFRONA COHORT Y. Balandina, Z. Simonova, Y. Tarlovskaya (Russia) A. Roy, P.A. Praveen, R. Amarchand, D. Prabhakaran, A. Krishnan, K.S. Reddy (India) 291 773 M. Gracia, A. Betriu, M. Martínez, D. Arroyo, M. Abajo, E. Fernández, J.M. Valdivielso (Spain) 765 A. Bea, E. Jarauta, R. Mateo-Gallego, S. Perez-Calahorra, V. Marco-Benedi, I. Lamiquiz-Moneo, L. Baila-Rueda, A. Cenarro, F. Civeira (Spain) 289 ANALYSIS OF THE DIRECT CAUSES OF DEATH IN PATIENTS WITH ACUTE STEMI TREATED WITH PRIMARY PCI FROM 2005 TO 2014 Y.H. Li, P.T. Lee, T.H. Chao, W.C. Tsai (Taiwan) Y.D. Jiang (Taiwan) 288 772 M. Schneider, C. Herz, C. Höbaus, R. Koppensteiner, G.H. Schernthaner (Austria) S.U. Kwon (Republic of Korea) 287 FACTORS PREDICTING SURVIVAL OVER TWO DECADES OF OBSERVATION AFTER PERIPHERAL PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY: A RETROSPECTIVE STUDY ASSOCIATION BETWEEN PREPROCEDURAL NON-HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS WITH THE INFLAMMATORY RESPONSE FOLLOWING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION781 F. Rached, F. Brito Jr, C. Garzillo, T. Nascimento, M.A. Perin, C.V. Serrano Jr (Brazil) 131 Poster Walks – Monday Board # 305 THE INCIDENCE AND SEVERITY OF ANGINA PECTORIS IN PATIENTS AFTER ELECTIVE PERCUTANEOUS CORONARY INTERVENTION (OPTIMA II) Board # 316 782 N. Logunova, Y. Karpov, V. Buza, D. Tomilova (Russia) 306 HYBRID INTERVENTION ON FEMOROPOPLITEAL ARTERIAL SEGMENT IN COMPARISON WITH CONVENTIONAL SURGICAL TECHNIQUE 307 PREVALENCE OF CARDIOVASCULAR RISK FACTORS IN MIDDLE-AGED SUBJECTS OF HIGH RISK LITHUANIAN POPULATION 317 MULTIPLE CORONARY FISTULAE INTO LEFT VENTRICLE AS A RARE CAUSE OF MYOCARDIAL ISCHEMIA 318 785 SUBCLINICAL MANIFESTATIONS OF ATHEROSCLEROSIS IN HYPERTENSIVE FEMALES WITH RHEUMATOID ARTHRITIS AND ITS RELATIONSHIP WITH THE ADIPONECTIN LEVEL, INSULIN RESISTANCE, ENDOTHELIAL FUNCTION 319 786 THE PREVALENCE OF CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUCOENCEPHALOPATHY (CADASIL) IN UZBEKISTAN 320 787 B. Muinjonov, E. Giyazitdinova (Uzbekistan) 311 7 T MRI REVEALS DIFFUSE IRON DEPOSITION IN PUTAMEN AND CAUDATE NUCLEUS IN CADASIL GENDER FEATURES OF MYOCARDIAL INFARCTION AND STROKE RISK IN GENERAL POPULATION WITH VITAL EXHAUSTION IN RUSSIA / SIBERIA: WHO PROGRAM MONICA-PSYCHOSOCIAL 795 RELATIONSHIP OF STRESS WITH METABOLIC SYNDROME AND CORONARY HEART DISEASE IN MIDDLE-AGED POLICE OFFICERS 796 M. Janczura, J. Dropinski, A. Stanisz, K. Kotula-Horowitz, R. Rosa, T. Domagala (Poland) O. Sirenko, O. Kuryata, T. Lysunets (Ukraine) 310 794 V. Gafarov, E. Gromova, I. Gagulin, D. Panov, A. Gafarova, M. Voevoda (Russia) A. Averkova, K. Savostyanov, D. Zateyshchikov (Russia) 309 OUTDOOR AIR POLLUTION AND ISCHEMIC STROKE SEVERITY: AN ECOLOGICAL STUDY IN THESSALONIKI N. Kakaletsis, K. Tziomalos, C. Savopoulos, M. Riga, S. Bouziana, M. Spanou, S. Kostaki, S. Angelopoulou, K. Karatzas, I.A. Hatzitolios (Greece) 784 S. Kutkiene, M. Petrylaite, Z. Petrulioniene (Lithuania) 308 A. Zotikov, Z. Adyrkhaev, V. Mitish, N. Ascerov, A. Kozhanova, A. Ivandaev, M. Abdulgamidov, A. Pokrovsky (Russia) 783 P. Puzdriak, V. Shlomin, Y. Didenko, Y. Yurtaev, M. Ivanov, P. Bondarenko, R. Magomedov (Russia) PATHOPHYSIOLOGICAL MECHANISMS FOR PRESERVING GRAFT PATENCY IN PATIENTS WITH COMPROMISED OUTFLOW TRACT AFTER DISTAL RECONSTRUCTION793 PRELIMINARY RESULTS OF THE EGYPTIAN CARDIOVASCULAR RISK FACTORS PROJECT:MULTICENTER OBSERVATIONAL STUDY OF THE PATTERN OF RISK FACTOR PROFILE IN EGYPTIAN PATIENTS WITH ACUTE CORONARY SYNDROME 797 W. Hamed, A. Reda, A. El-Kersh, A. Shalaby, M. Beshay (Egypt) 788 B. Muinjonov, E. Giyazitdinova (Uzbekistan) 312 TENASCIN-C DEFICIENCY ATTENUATES ABDOMINAL AORTIC ANEURYSM FORMATION789 A.K. Schaefer, F. Nagel, P. Kaiser, D. Santer, K. Trescher, A. Kiss, B.K. Podesser (Austria) 313 A CASE OF FATAL OBSTRUCTIVE SHOCK 790 A. Almaghraby, Y. Saleh, B. Hammad, A. Samoka, M. Elbahey, M. Seleem (Egypt) 314 CARDIOVASCULAR RISK FACTORS IN WOMEN AND MEN 791 A. Nikolova, M. Milanova (Bulgaria) 315 CAROTID INTIMA-MEDIA THICKNESS AS A PROGNOSTIC RISK MARKER OF DEMENTIA AT THE ELDERLY 792 R. Dascalescu, A. Zamfirescu, S.M. Aurelian, O. Stanciu, A. Capisizu (Romania) 132 133 Poster Walks – Monday Abstract not Registered 400 THE ZINC-SUPPLEMENTED TO RABBITS FED A HIGH CHOLESTROL DIET DELAYS THE PROGRESSION OF ATHEROSCLEROSIS 411 798 Y. Al mohy (Kingdom of Saudi Arabia) 401 412 EVALUATION OF THE SAFETY AND EFFICACY OF STATIN IN ELDERLY PATIENTS 799 CD34+ BONE MARROW DERIVED CELLS INHIBIT INTIMAL HYPERPLASIA IN MOUSE MODEL OF VASCULAR INJURY ESCHERICHIA COLI LIPOPOLYSACCHARIDE AND CPG MAY AFFECT ATHEROGENESIS THROUGH THE MODULATION OF ENDOTHELIAL BARRIER AND TOLEROGENIC PHENOTYPE OF APOLIPOPROTEIN B100PULSED DENDRITIC CELLS 800 MODIFICATIONS OF LOW DENSITY LIPOPROTEIN IN ATHEROSCLEROSIS 413 414 ISCHEMIC HEART DISEASE AND EARLY DIAGNOSIS. STUDY ON THE PREDICTIVE VALUE OF 2D STRAIN 415 REDUCED AVAILABILITY OF DIETARY CHOLESTEROL IN INFANCY PROGRAMS THE INTESTINAL CHOLESTEROL ABSORPTION DURING ADULTHOOD IN MICE 416 803 CARDIOVASCULAR RISK AND PROINFLAMMATORY CYTOKINES IN PATIENTS WITH METABOLIC SYNDROME 417 IS HIGH-DENSITY LIPOPROTEIN SUITABLE PREDICTOR FOR DEVELOPMENT OF METABOLIC SYNDROME: A 10-YEAR FOLLOW-UP IN ADULTS 804 VIOLATIONS IN THE LEVEL OF SERUM LIPIDS APPEAR AT ALL PATIENTS WITH PROSTATITIS THAT IS ASSOCIATED WITH DECREASE IN THE LEVEL OF THE FREE TESTOSTERONE 805 418 419 ON THE DEVELOPMENT OF ANTI-ATHEROSCLEROTIC DRUGS ON THE BASIS OF NATURAL PRODUCTS USING CELL CULTURES IMPACT OF THE LIPID AND ANTHROPOMETRIC PARAMETERS ON THE LDL(-) AND AUTOANTIBODIES ANTI-LDL(-) 814 LIFESTYLE - THE SILENT KILLER, LEADING TO CARDIOVASCULAR EVENTS ACROSS CONTINENTS IN YOUNG APPARENTLY HEALTHY INDIANS 815 BURDEN OF CARDIOVASCUlaR RISK IN YOUNG, APPARENTLY HEALTHY INDIANS IN UK & INDIA. TIME FOR INTERVENTION? 816 420 817 IN VIVO/EX VIVO INTEGRATED IMAGING MODEL FOR CORONARY AND CAROTID PLAQUE RISK ASSESSMENT: A PROOF OF CONCEPT STUDY 818 G. Pelosi, D. Panetta, A. Sakellarios, N. Filipovic, T. Exarchos, V. Federico, C. Fiorentini, A. Gennaro, S. Rocchiccioli, P.A. Salvadori, M.G. Trivella, D. Fotiadis, O. Parodi (Italy) 807 421 808 RELATIONSHIP OF CAROTID AND FEMORAL ARTERY INTIMA-MEDIA THICKNESS WITH HISTOPATHOLOGIC ARTERIAL ATHEROSCLEROSIS IN CHRONIC KIDNEY DISEASE N. Nezami, K. Ghabili, B. Shokouhi, M. Mirchi, M. Gojazadeh, S. Ghorashi, M.K. Tarzamni (USA) 806 A. Govorin, D. Zaytsev (Russia) 410 813 R. Narain, S. Sharma (United Kingdom) M. Gharipour, M. Sadeghi, N. Sarrafzadegan (Iran) 409 THE ROLE OF OXIDATIVE STRESS ON AMYLOID-LIKE PROTEIN FORMATION AND AORTIC VALVE CALCIFICATION R. Narain, A. Pulikal, S. Sharma (United Kingdom) R. Dragut, E. Rusu, R. Nan, H. Popescu, F. Rusu, M. Jinga, A. Cursaru, L. Grosu, G. Radulian (Romania) 408 DYSLIPIDEMIA IN PATIENTS WITH HEART FAILURE AND HYPOTHYROIDISM 812 A.P.Q. Mello, I.T. Silva, N.R.T. Damasceno (Brazil) L.G. Dimova, J.F. De Boer, T. Plösch, H.J. Verkade, U.J.F. Tietge (Netherlands) 407 811 I. Mamarelis, E. Koutoulakis, C. Kotoulas, V. Mamareli, V. Dritsa, J. Anastassopoulou (Greece) 802 G. Dattilo, A. Lamari, M. Casale, E. Imbalzano, P. Busacca, C. De Gregorio, G. Di Bella (Italy) 406 HYPOTHYROIDISM IS THE INDEPENDENT FACTOR OF ATHEROSCLEROSIS A. Logvinenko (Ukraine) 801 G.I. Constantin, S. Opris (Romania) 405 810 O. Kupchynskaya, N. Tsyrulneva, O. Gulkevych, V. Bezrodnyi, M. Mospan, A. Logvinenko (Ukraine) M. Chalubinski, K. Wojdan, E. Luczak, P. Gorzelak, G. Katarzyna, B. Maciej, G. Adrian, R. Karolina, C. Magdalena, B. Marlena (Poland) 404 Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics W.Y. Lo, H.J. Wang (Taiwan) S. Ananthaseshan, E. Kurzejamska, M. Lazarczyk, P. Religa (Sweden) 403 809 H. Liu, H. Yongqiang, W. Hongyu, L. Jinbo (China) R. Alves, C. Gonçalves, N. Borges Jr (Brazil) 402 POSSIBLE ASSOCIATION BETWEEN COMMON CAROTID ARTERY LUMEN DIAMETER AND VASCULAR FUNCTION IN NATURAL POPULATIONS OF SHE MINORITY FROM FUJIAN PROVINCE IN CHINA SYNTAX SCORE AS A MARKER OF PLURIDISTRICTUAL ATHEROSCLEROSIS 819 G. Polizzi, S. Evola, S. Novo, V. Evola (Italy) S. Jargin (Russia) 134 135 422 PERCUTANEOUS TRANSVENOUS MITRAL COMMISSUROTOMY IN PATIENTS WITH CALCIFIC MITRAL STENOSIS : IMMEDIATE AND INHOSPITAL CLINICAL, ECHOCARDIOGRAPHIC AND HEMODYNAMIC OUTCOME820 T. Rahman, A.A.S. Majumder, M.Z. Ali (Bangladesh) 423 THE EFFECT OF PINACIDIL ON HUMAN SAPHENOUS VEINS OBTAINED FROM THE PATIENTS WITH AND WITHOUT DIABETES MELLITUS TYPE 2 821 J. Rajkovic, M. Peric, R. Novakovic, D. Nezic, V. Djokic, V. Zivanovic, V. Kanjuh, H. Heinle, L. Gojkovic-Bukarica (Serbia) 424 SR-BI antagonises the S1P/S1PR2-mediated pro-inflammatory effects induced by ox-LDL in HUVECs 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria 822 K. Ren, Y.J. Lu, X. Liu, Q.H. Zhang, Z.C. Mo, Z.L. Tang, Y. Jiang, X.S. Peng, G.H. Yi (China) 425 ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. 823 K. Ren, X. Liu, R. Suo, S.L. Xiong, Q.H. Zhang, Z.C. Mo, Z.L. Tang, J. Yue, X.S. Peng, G.H. Yi (China) 426TGF-β down-regulates apolipoprotein M expression via the TAK1-JNK-c-Jun pathway in HepG2 cells 824 K. Ren, X. Liu, Z.C. Mo, Q.H. Zhang, Z.L. Tang, Y. Jiang, X.S. Peng, G.H. Yi (China) 427 THE HYPERCHOLESTEROLEMIC SWINE MODEL OF ATHEROGENESIS: STATISTICAL APPROACHES TO MOLECULAR MARKERS AND PLAQUE MORPHOLOGY ASSOCIATION 825 S. Rocchiccioli, G. Pelosi, A. Cecchettini, E. Capobianco, M.G. Trivella (Italy) 428 A NEW MARKER FOR ST ELEVATION MYOCARDIAL INFARCTION: PRESEPSIN? 826 F.N. Turhan caglar, N. Isikssacan, I. Biyik, F. Akturk, S. Opan, H. Cebe, I. Ungan, O. Karakaya (Turkey) 429 THE ROLE OF CHOLESTERYL ESTER TRANSFER PROTEIN EXPRESSION ON ENDOTHELIAL CELLS: OXIDATIVE STRESS AND VASCULAR DYSFUNCTION. 827 A. Wanschel, E. Lorza, A. Paiva, J. Stravinsky, D. Gabriel, T. Rentz, D. Guizoni, A. Davel, A. Salerno, H. Oliveira (Brazil) 430 THE EFFECT OF OXIDIZED CHOLESTEROL ON BARRIER FUNCTIONS AND IL-10 MRNA EXPRESSION IN HUMAN INTESTINAL EPITHELIUM COCULTURED WITH DENDRITIC CELLS IN THE TRANSWELL SYSTEM 828 K. Wojdan, M. Chalubinski, P. Gorzelak, M. Borowiec, M. Broncel (Poland) 431 IMPROVEMENT OF HIGH-DENSITY LIPOPROTEIN FUNCTIONALITY BY COCONSUMPTION OF HIGH DOSAGE VITAMIN C AND CLOVE VIA CETP INHIBITION 829 J.A. Yoo, K.H. Cho 432 IMPACT OF AN ABDOMINAL AORTIC CALCIFICATION ON THE MORPHOLOGY OF LOW LIMB ARTERY ATHEROSCLEROSIS V. Zelinskiy, M. Melnikov, V. Andreev, S. Alexandra (Russia) 136 830 II t if h S n io t a t n e s Poster Pre y 31– Tuesday, Ma 1 e n u J , y a d s e n Wed www.eas2016.kenes.com Poster Walks – tuesday Board # Tuesday, May 31, 2016 Metabolic Abnormalities and Atherosclerosis: Diabetes 001 MODY TYPE DIABETES MELLITUS AND COGNITIVE IMPAIRMENT 831 B. Muinjonov, E. Giyazitdinova (Uzbekistan) 002 POLYMORPHISM IN GENES INVOLVED IN LIPID METABOLISM IN MODY PATIENTS832 E. Shakhtshneider, A. Ovsyannikova, A. Kurilshikov, D. Ivanoshchuk, O. Rymar, Y. Ragino, M. Voevoda (Russia) 003 METABOLIC CONTROL IN TYPE 2 DIABETIC PATIENTS 833 B. Orhan (Turkey) 004 ONE-YEAR RESULTS OF A MULTIDISCIPLINARY SCREENING PROGRAM FOR DIABETES, CARDIOVASCULAR AND PULMONARY DISEASES AMONG 67-YEARS OLD CITIZENS IN VIBORG MUNICIPAL, DENMARK 834 A. Høgh, M. Dahl, J. S. Lindholt (Denmark) 005 DIFFERENCES IN LIPID PROFILE CONTROL AMONG DIABETIC PATIENTS AT VERY HIGH CARDIOVASCULAR RISK ACCORDING TO THEIR CLINICAL FEATURES835 D. García Fuertes, E. Villanueva Fernández, M. Crespín Crespín, F.J. Castillo Bernal, I. Guerado Espinosa, M.C. Castro Jiménez, A. Rodríguez Cubero (Spain) 006 FACTORS RELATED TO THE APPEARANCE OF MAJOR EVENTS DURING FOLLOW-UP OF DIABETIC PATIENTS AT VERY HIGH CARDIOVASCULAR RISK 836 M. Crespín Crespín, D. García Fuertes, E. Villanueva Fernández, F.J. Castillo Bernal, A. Rodríguez Cubero, I. Guerado Espinosa, M.C. Castro Jiménez (Spain) 007 CONTROL OF CARDIOVASCULAR RISK FACTORS IN A NON-SELECTED COHORT OF DIABETIC PATIENTS AT VERY HIGH CARDIOVASCULAR RISK 837 E. Villanueva Fernández, D. García Fuertes, M. Crespín Crespín, F.J. Castillo Bernal, M.C. Castro Jiménez, A. Rodríguez Cubero, I. Guerado Espinosa (Spain) 008 THE IMPORTANCE OF HDL CHOLESTEROL LEVELS IN DIABETIC INDIVIDUALS : 9.2-YEAR SURVEY OF CARDIOVASCULAR EVENTS 838 K. Ina, T. Hayashi, M. Kuzuya (Japan) 009 CONCORDANCE OF GLUCOSE BASED AND OF HbA1c BASED DIAGNOSES OF DIABETES IN PATIENTS WITH ESTABLISHED CORONARY ATHEROSCLEROSIS - A COMPARISON BETWEEN MEN AND WOMEN 839 C. Saely, D. Zanolin, P. Rein, A. Vonbank, A. Leiherer, A. Muendlein, H. Drexel (Austria) 139 Poster Walks – tuesday Board # Board # 010 020 ASSOCIATION OF INSULIN RESISTANSE WITH CAROTID INTIMA-MEDIA THICKNESS AND BRACHIAL FLOW-MEDIATED DILATION IN THE SUBJECTS WITH METABOLIC SYNDROME 011 ASSOCIATION OF INSULIN RESISTANCE, AS DETERMINED BY HOMEOSTASIS MODEL ASSESSMENT (HOMA), WITH METABOLIC SYNDROME AMONG MIDDLE-AGED SUBJECTS 021 012 DYSLIPIDEMIA WITH AND WITHOUT INSULIN RESISTANCE: SIMILARITIES AND DIFFERENCES 022 013 DYSLIPIDEMIA CONTROL IN TYPE 2 DIABETES: EXPERIENCE OF A PORTUGUESE CENTRE IN THE LAST DECADE 023 843 J. Sequeira Duarte, C. Tavares Bello, R. Fonseca, R. Ferreira, M. Oliveira, C. Saraiva, C. Gouveia, F. Santos, J. Azinheira, C. Vasconcelos (Portugal) 014 CORRELATION BETWEEN HOMOCYSTEINE AND TYPE-2 DIABETES MELLITUS COMPLICATIONSCORRELATION BETWEEN HOMOCYSTEINE AND TYPE-2 DIABETES MELLITUS COMPLICATIONS 015 SERUM APOLIPOPROTEIN B48 CONCENTRATION IS HIGH IN PATIENTS WITH IMPAIRED GLUCOSE TOLERANCE AND INCREASES AFTER ORAL GLUCOSE INGESTION IN PATIENTS WITH DIABETES MELLITUS 016 025 026 027 ALTERATIONS OF METABOLIC PARAMETERS AND ANTIOXIDANT ENZYMES IN DIABETIC AGING FEMALE RAT BRAIN: NEUROPROTECTIVE ROLE OF METFORMIN847 CARDIO- AND NEPHROPROTECTIVE EFFECTS OF EZETIMIBE/ SIMVASTATIN COMBINATION IN TYPE 2 DIABETES MELLITUS 028 ROLE OF NEW ADIPOKINES IN THE PATHOGENESIS OF ATHEROSCLEROSIS IN MORBIDLY OBESE SUBJECTS A. Gentili, P. Trayhurn, S.Y. Alomar, M.S. Zaibi, S. De Vuono, M.A. Ricci, A. Alaeddin, D. Siepi, M. Boni, G. Vaudo, G. Lupattelli (Italy) 140 854 BMI IS NOT AN IMPORTANT FACTOR FOR THE DEVELOPMENT OF SUBCLINICAL ATHEROSCLEROSIS IN ELDERLY DIABETIC SUBJECTS WITH METABOLIC SYNDROME 855 RESVERATROL AND QUERCETIN PROTECT ISOLATED MOUSE CORPORA CAVERNOSA FROM IN VITRO-INDUCED DIABETIC ERECTILE DYSFUNCTION 856 DIABETIC VASCULAR DISEASE AND MATURITY-ONSET DIABETES OF THE YOUNG 857 029 848 849 RELATIONSHIP BETWEEN 25 HYDROXY-VITAMIN D AND ANKLE BRACHIAL INDEX IN TYPE 2 DIABETIC PATIENTS 858 S. Lahiani, I. Oueslati, K. Bouzid, K. Khiari, S. Ghezaiel, H. Ben Ahmed, H. Belhadj Hassen, H. Baccar, J. Abdelmoula, N. Ben Abdallah (Tunisia) ANKLE BRACHIAL INDEX IN THE PREDICTION OF CORONARY HEART DISEASE IN TYPE 2 DIABETIC PATIENTS 859 K. Bouzid, H. Ben Ahmed, I. Oueslati, S. Lahiani, K. Khiari, N. Khessairi, J. Belagha, S. Ghezaiel, N. Ben Abdallah, H. Baccar, J. Abdelmoula (Tunisia) R. Sayfutdinov, O. Bugrova, O. Boeva (Russia) 019 EFFECT OF THE EDUCATION IN HOSPITALIZATION OF DIABETIC INDIVIDUALS FOR DIABETES CONTROL AND PREVENTION OF COMPLICATIONS AS A TOOL OF HOSPITAL AND CLINIC COOPERATION J.M. Mafra, G. Gaspar, M. Bourbon (Portugal) P. Kumar, N. Baquer (India) 018 853 C. Boydens, B. Pauwels, L. Vandendaele, J. Van de Voorde (Belgium) E. Georgousopoulou, D. Panagiotakos, C. Chrysohoou, I. Skoumas, A. Laskaris, C. Stefanadis, C. Pitsavos (Greece) 017 SERUM LEVELS OF SOLUBLE RECEPTOR FOR ADVANCED END PRODUCTS ARE ASSOCIATED WITH RESTENOSIS OCCURRENCE IN PATIENTS WITH DIABETES MELLITUS AFTER DRUG-ELUTING STENT IMPLANTATION G. Yoshino, H. Yoshino, T. Ann, K. Kawakami, T. Akiyama, Y. Inoue (Japan) 845 FASTING INSULIN LEVELS PREDICT FATAL CARDIOVASCULAR (CVD) EVENTS MORE ACCURATELY THAN ANY OTHER MARKER OF GLUCOSE METABOLISM. THE 10-YEAR FOLLOW-UP OF THE ATTICA STUDY (2002-2012) 846 852 T. Hayashi, K. Ina, M. Kuzuya (Japan) 844 D. Masuda (Japan) RELATIONSHIP BETWEEN CAROTID ARTERY INTIMA-MEDIA THICKNESS AND CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH DIABETES S. Kozlov, Z. Gabbasov, S. Byazrova, O. Saburova, V. Masenko (Russia) 024 M. Akhvlediani, M. Emukhvari, N. Zabakhidze, T. Kvantaliani (Georgia) 851 V. Vasilkova, T. Mokhort, E. Naumenko (Belarus) 842 I. Pchelin, N. Hudiakova, A. Shishkin, O. Vasilkova (Russia) SEVERITY OF ATHEROSCLEROTIC LESIONS AND FOOT SYNOVIAL TENDON COMPLEX INJURY AS FACTORS OF SEPSIS DEVELOPMENT IN PATIENTS WITH DIABETIC FOOT E. Shalaeva, B. Janabaev, Q. Matmurotov, U. Kasimov, U. Pulatov, A. Bobabekov (Uzbekistan) 841 M. Janczura, K. Kotula-Horowitz, T. Iwaniec, A. Stanisz, J. Dropinski, T. Domagala (Poland) 850 D. Gabrielyan, L. Gabrielyan, A. Artemova, D. Zhokhov, M. Ivanov, P. Bondarenko, M. Ermina, A. Yadernaya (Russia) 840 T. Domagala, M. Janczura, K. Kotula-Horowitz, J. Dropinski, T. Iwaniec, J. Zagajewski, A. Stanisz (Poland) DOES TYPE 2 DIABETES ASSOCIATE ATHEROSCLEROTIC PROCESS? 030 CARDIOVASCULAR EFFECTS OF INCRETINS IN PATIENTS WITH TYPE 1 DIABETES860 M. Arutyunova, A. Glazunova, S. Martynov, I. Klephortova, A. Ilyin, O. Manchenko, I. Ulianova, M. Shamkhalova, M. Shestakova (Russia) 141 Poster Walks – tuesday Board # 031 SEVERITY OF CORONARY ARTERY STENOSIS IN PATIENTS WITH CRITICAL PERIPHERAL ARTERY DISEASE UNDERGOING HIGH AMPUTATION Board # 041 861 E. Shalaeva, B. Janabaev, B. Babadjanov, Q. Matmurotov, U. Kasimov, U. Pulatov, A. Bobabekov (Uzbekistan) 032 HIGH PREVALENCE OF NON DIPPERS HYPERTENSIVE DIABETIC PATIENTS: THE ROLE OF AMBULATORY BLOOD PRESSURE MONITORING IN EFFECTIVE TREATMENT THE IMPACT OF BARIATRIC SURGERY ON CARDIOMETABOLIC PROFILE AND ADIPOKINE LEVELS 042 862 BARIATRIC SURGERY IMPROVES LIPID PROFILE IN MORBIDLY OBESE PATIENTS BY LOWERING LDL-C AND INCREASING HDL-C AND THE LARGE HDL-PARTICLES 863 035 EFFECTS OF BARIATRIC SURGERY ON MICROVASCULAR DYSFUNCTION AND METABOLIC PROFILE IN MORBID OBESITY FACTORS DETERMINING AND STRATEGIES FOR IMPROVING TREATMENT ADHERENCE IN PATIENTS WITH TYPE 2 DIABETES MELIITUS: DOCTOR, COMMUNITY PHARMACIST AND PATIENT PERSPECTIVES. ADHERI2 STUDY. 864 045 PREVALENCE OF 25 HYDROXY-VITAMIN D DEFICIENCY AND ITS CORRELATION WITH GLYCEMIC CONTROL IN DIABETIC PATIENTS 865 COMBINED DEVELOPMENT OF MACROVASCULAR AND CHRONIC KIDNEY DISEASE IN TYPE 2 DIABETES ASSOCIATED WITH POLYMORPHISM OF TNF-α GENE 046 866 047 867 048 868 INCREASED INFLAMMATORY EFFECT ON MONOCYTES OF ELECTRONEGATIVE LDL AND DECREASED PROTECTION BY HDL FROM POORLY CONTROLLED TYPE 2 DIABETIC PATIENTS 876 TRANSGENIC OVEREXPRESSION OF THE NRF2 AMELIORATES INSULIN RESISTANCE AND CHANGES FATTY ACIDS IN MEMBRANE PHOSPHOLIPIDS IN SPONTANEOUSLY HYPERTENSIVE RATS 877 HYPOLIPIDEMIC THERAPY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: ANALYSIS TYPICAL APPROACHES 878 049 DIABETES AWARENESS AMONG CORONARY DISEASE PATIENTS DIFFERS SIGNIFICANTLY BETWEEN MEN AND WOMEN 879 C. Saely, D. Zanolin, A. Vonbank, A. Leiherer, H. Drexel (Austria) FEATURES OF VASCULAR REMODELING AND METABOLIC DISORDERS IN PATIENS WITH ESSENTIAL HYPERTENSION AND CONCOMITANT TYPE 2 DIABETES DEPENDING ON GENETIC POLYMORPHISM PPARγ2869 NEUTROPHIL/LYMPHOCYTE RATIO AND VASCULAR INFLAMMATION IN OBESE WOMEN 875 I. Sapozhnikova, E. Tarlovskaya (Russia) A. Shalimova, A. Belovol, L. Bobronnikova, M. Kochueva (Ukraine) 040 ASSOCIATION BETWEEN NT-PROBNP AND VISCERAL ADIPOSITY I. Markova, H. Malinska, O. Oliyarnyk, L. Kazdova, M. Pravenec (Czech Republic) O. Vikulova, N. Lebedeva, A. Zheleznyakova, A. Nikitin, M. Shamkhalova, M. Shestakova (Russia) 039 ASSOCIATION OF DIFFERENT CHOLESTEROL HOMEOSTASIS PATTERNS WITH ABDOMINAL OBESITY IN PATIENTS WITH CORONARY ARTERY DISEASE 874 M. Estruch-Alrich, I. Miñambres, J.L. Sánchez-Quesada, A. Pérez-Pérez, J. Ordóñez-Llanos, S. Benítez (Spain) S. Lahiani, K. Bouzid, I. Oueslati, K. Khiari, N. Bchir, A. Melki, A. Bartkiz, H. Ben Ahmed, H. Baccar, J. Abdelmoula, N. Ben Abdallah (Tunisia) 038 873 J. Suwa (Japan) E. Labrador-Barba, A. Hernández-Mijares, M. Rodríguez-de Miguel, M.J. Faus-Dader, M.L. Orera-Peña, F.J. Alonso Moreno (Spain) 037 CINNAMALDEHYDE ATTENUATES HIGH GLUCOSE-INDUCED OXIDATIVE STRESS AND ENDOTHELIAL DYSFUNCTION AS AN Nrf2 ACTIVATOR S. Vladimirov, T. Gojković, V. Spasojević-Kalimanovska, A. Zeljković, J. Vekić, D. Kalimanovska-Oštrić, Z. Jelić-Ivanović (Serbia) M. Naeimi Kararoudi, G. Lupattelli, S. Ministrini, V. Bianconi, M.A. Ricci, S. De Vuono, P. Mariani, A. Moriconi, M. Boni, E. Mannarino, L. Pasqualini (Italy) 036 872 F. Wang, P. Wang, J. Wan, J. Hou, P. Zhou (China) 044 C.A. Kjellmo, T. Nestvold, K.T. Lappegård, A. Hovland, M. Mathisen (Norway) LpPLA2 IN GESTATIONAL DIABETES MELLITUS - A PROTECTIVE SYSTEM FOR PLACENTA AND FETUS? C. Wadsack (Austria) 043 F. Reis de Azevedo Rabello, S. Santoro dos Santos Pereira, M.L. CorrêaGiannella, D. Giannella Neto, E. Sant'Anna Melo, B. Caramelli (Brazil) 034 871 J. Piťha, P. Pithova, P. Stavek, J.A. Hubacek, O. Auzky, T. Neskudla, T. Pelikanova, M. Kvapil (Czech Republic) V. Manea, C. Pop, L. Pop (Romania) 033 GENE FOR CONNEXIN 37 IS ASSOCIATED WITH ATHERSCLEROTIC CHANGES IN WOMEN WITH DIABETES MELLITUS TYPE 2. 050 880 V. Sharma (India) 051 870 INDIAN DIABETES RISK SCORE (IDRS) FOR TYPE 2 DIABETES MELLITUS SCREENING IN YOUNG ADULTS: EFFECT OF YOGA AND MEDITATION ASSOCIATION OF RED CELL DISTRIBUTION WIDTH WITH CORONARY ARTERY DISEASE IN PATIENTS WITH DIABETES IN MULTI-ETHNIC SINGAPORE 881 C. Chiong, Y.J. Chee, X. Gao, R. Dalan (Singapore) B. Ilincic, M. Djeric, E. Stokic, R. Mijovic, S. Nikolic, Z. Stosic (Serbia) 142 143 Poster Walks – tuesday Board # Board # 052 061 PREDICTORS OF 10-YEAR MORTALITY ARE DIFFERENT IN DIABETIC AND NON-DIABETIC PATIENTS WITH CHRONIC LOWER EXTREMITY PERIPHERAL ARTERIAL DISEASE 882 T. Mueller, F. Hinterreiter, W. Poelz, M. Haltmayer, B. Dieplinger (Austria) 053 HAND GRIP STRENGTH SIGNIFICANTLY PREDICTS CARDIOVASCULAR EVENT RISK IN PATIENTS WITH TYPE 2 DIABETES MELLITUS TELMISARTAN ATTENUATES HYPERGLYCEMIA-AGGRAVATED VCAM1 EXPRESSION AND MONOCYTES ADHESION IN TNFα-STIMULATED ENDOTHELIAL CELLS BY INCREASING GSK3β-SER9 PHOSPHORYLATION 062 883 GENETIC VARIANTS AND LIPID TRAITS IN THE HONG KONG CHINESE PATIENTS WITH TYPE 2 DIABETES 063 884 ANTIATHEROGENIC EFFECT OF METFORMIN IN TWO MOUSE LINES WITH DIFFERENT SUSCEPTIBILITY TO GLUCOSE INTOLERANCE 064 885 065 886 Metabolic Abnormalities and Atherosclerosis: Adipose Tissue ADIPOKINES AND CYTOKINES SERUM LEVELS IN CHILDREN AND ADOLESCENTS AND ITS RELATIONSHIP WITH OBESITY 887 INDUCIBILITY OF TRIGLYCERIDE TURNOVER IN WHITE FAT – A MARKER OF LEAN PHENOTYPE 888 144 895 EFFECT OF BMI ON EPICARDIAL FAT ,CARDIAC CHAMBERS AND CORONARY CALCIFICATION CORRELATIONS 896 ARE WE FOLLOWING THE GUIDELINES TO PREVENT CONTRAST INDUCED ACUTE KIDNEY INJURY? A CLINICAL AUDIT ON PATIENTS WITH CHRONIC KIDNEY DISEASE(CKD) UNDERGOING CORONARY ANGIOGRAM 897 EFFECT OF RECOMMENDED DIETARY PROTEIN RESTRICTION ON THE PROGRESSION OF KIDNEY DISEASE 898 C. Visinoni, A. Baragetti, I. Baragetti, C. Biazzi, K. Garlaschelli, L. Grigore, C. Pozzi, N. Giuseppe Danilo, C. Alberico L (Italy) 889 RELATIONSHIP OF ORPHAN RECEPTOR RORA AND CHOLESTEROL TRANSPORTERS ABCA1 AND ABCG1 EXPRESSION IN VISCERAL ADIPOSE TISSUE890 V. Miroshnikova, A. Panteleeva, E. Demina, T. Usenko, E. Bazhenova, I. Semenova, O. Berkovich, E. Baranova, S. Pchelina (Russia) OVARIECTOMY AFFECTS SUBSTRATE UTILIZATION IN BROWN ADIPOSE TISSUE AND INDUCES LIVER DICARBONYL STRESS IN RATS V. Kanthasamy, S. Gill (United Kingdom) 068 K. Adamcova, P. Flachs, P. Zouhar, K. Bardova, M. Svobodova, P. Janovska, A. Keenan, L. Madsen, J. Jones, K. Kristiansen, J. Kopecky (Czech Republic) 060 894 Metabolic Abnormalities and Atherosclerosis: Kidney 067 C. Rodriguez-Leal, M. Monsalvo-Hernando, I. Tinoco-Racero, E. Segura, N. Caro, M. Lagares Carballo, A. Perez, C. Perez, M. Rodriguez -Rosety, T. Pery, A. Mangas, T. Rocio (Spain) 059 LIPOSOMES FOR MICRORNA DELIVERY TO HUMAN ADIPOCYTES H. Alnafakh, H. Nafakhi, A. Albasri, A. Almusawi (Iraq) A. Almusawi, H. Nafakhi, H. Alnafakh, A. Albasri (Iraq) 058 893 J. Trnovska, H. Malinska, V. Skop, L. Kazdova (Czech Republic) 066 EPICARDIAL FAT ,CARDIAC CHAMBERS AND CORONARY CALCIFICATION IN HYPERTENSIVE PATIENTS RELATION BETWEEN EPICARDIAL FAT TISSUE AND INFLAMMATORY MARKERS IN PREGNANTS WITH PREECLAMPSIA G. Schratter, M. Karbiener, G. Almer, H. Mangge, M. Scheideler, R. Prassl (Austria) A. Asai, Y. Shuto, M. Nagao, T. Miyazawa, H. Sugihara, S. Oikawa (Japan) 057 892 H.A. Cakmak, B. Dincgez Cakmak, C. Yayla Abide, E. Inci Coskun, M. Erturk (Turkey) M. Hu, C. Tam, W.Y. So, J. Chan, B. Tomlinson, R. Ma (Hong Kong- China) 056 COLD-INDUCED CHANGES IN WHITE ADIPOSE TISSUE OF A/J AND C57BL/6J MICE K. Bardova, P. Flachs, K. Adamcova, M. Svobodova, J. Kopecky (Czech Republic) D.H. Cho, J.E. Lee, K.H. Song (Republic of Korea) 055 891 A. Albasri, H. Nafakhi, A. Almusawi, H. Alnafakh (Iraq) P. Rein, C. Saely, A. Vonbank, D. Zanolin, A. Leiherer, H. Drexel (Austria) 054 EPICARDIAL FAT AND BMI RELATIONSHIPS WITH CORONARY ATHEROSCLEROTIC MARKERS IN PATIENTS WITH CORONARY CALCIUM SCORE >0: THE EFFECT OF AGE AND GENDER 069 VERY MILD RENAL ENDOTHELIAL DAMAGE AND GLOMERULAR HYPERFILTRATION MAY PRECEDE INCIDENT HYPERTENSION IN THE JAPANESE GENERAL POPULATION: THE WATARI STUDY 899 M. Munakata, T. Hattori, S. Konno (Japan) 070 EARLY BIOMARKERS OF CHRONIC KIDNEY DISEASE IN DIABETIC PATIENTS 900 Z. Zuraeva, O. Mikhaleva, O. Vikulova, A. Ilyin, M. Shamkhalova, M. Shestakova (Russia) 145 Poster Walks – tuesday Board # 071 CHOLESTEROL LEVELS AND GLOMERULAR FILTRATION RATE - IS THERE ANY ASSOCIATION? Board # 081 901 J. Frutuoso, M. Bourbon (Portugal) 072 HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND CONTRASTINDUCED ACUTE KIDNEY DISEASE IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION EVALUATION OF THE ASSOCIATION OF PLASMA PENTRAXIN 3 LEVELS WITH TYPE 2 DIABETES AND DIABETIC NEPHROPATHY IN PATIENTS WITH RENAL FAILURE. 902 075 Metabolic Abnormalities and Atherosclerosis: NASH and Liver Abnormalities 082 903 P. Miarka, M. Walus-Miarka, D. Fedak, M. Kuzniewski, A. Pietrzycka, E. Wieczorek-Surdacka, P. Jasik, B. Przepiorkowska-Hoyer, M. Kapusta, B. Idzior-Walus, W. Sulowicz (Poland) 074 083 CARDIOMETABOLIC RISK IN PATIENTS WITH CHRONIC RENAL DISEASE RELATED TO HYPERTRIGLYCERIDEMIA-LOW HDL -CHOLESTEROL ASSOCIATION 904 084 CORRELATION OF THYROID STIMULATING HORMONE TO KIDNEY FUNCTION OF HEALTHY RESIDENTS: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY (KOPS) 085 ISHCEMIC PRECONDITIONING IN CONTRAST-INDUCED NEPHROPATHY PROPHYLACTICS IN PATIENTS WITH MILD CHRONIC KIDNEY FAILUTE 905 CHARACTERISTICS OF LONG-TERM SURVIVORS IN A DIABETIC DIALYSIS PATIENT COLLECTIVE (4D STUDY) 906 086 EVALUATION OF CARDIOVASCULAR RISK IN PATIENTS WITH CHRONIC KIDNEY DISEASE 087 907 ADULT RELAPSING FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS) MAINTAINED IN PARTIAL REMISSION FOLLOWING LIPOPROTEIN APHERESIS: CASE STUDY A. Haikal, N. Sehar, L. Denney, P. Moriarty (USA) 146 914 CONTINUOUS GRADING OF EARLY FIBROSIS IN NAFLD USING LABEL-FREE IMAGING915 THE ROLE OF VITAMIN D3 IN HIGH FAT DIET INDUCED FATTY LIVER DISEASE AND OBESITY. 916 COMPARATIVE ANALYSIS OF SERUM LIPIDS IN PATIENTS WITH CHRONIC HEPATITIS C, NONALCOHOLIC FATTY LIVER DISEASE, AND HEALTHY CONTROLS917 R. Ivanova, I. Valkov, C. Marinova, A. Alexiev, K. Antonov, D. Jelev, L. Mateva (Bulgaria) 908 088 LIPID-MODIFYING EFFECTS OF CURCUMIN IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE 918 Y. Panahi, P. Kianpour, R. Mohtashami, R. Jafari, A. Sahebkar (Iran) 909 089 I. Oueslati, S. Lahiani, K. Bouzid, K. Khiari, H. Kaaroud, E. Elfaleh, A. Bartkiz, N. Ben Abdallah, J. Abdelmoula (Tunisia) 080 CARDIOMETABOLIC RISK FACTORS IN YOUNG V/S MIDDLE-AGED PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE R. Kheder, J. Hobkir, M. Browning, C. Stover (United Kingdom) S. Triebswetter (Germany) 079 913 J. Pirhonen, J. Arola, S. Sädevirta, P. Luukkonen, S.M. Karppinen, T. Pihlajaniemi, A. Isomäki, M. Hukkanen, H. Yki-Järvinen, E. Ikonen (Finland) N. Zagidullin, A. Dunaeva, E. Sherbakova, S. Zagidullin (Russia) 078 ASSOCIATION BETWEEN SERUM MONOCYTE CHEMOATTRACTANT PROTEIN-1(MCP-1) LEVELS, INSULIN RESISTANCE AND SUBCLINICAL ATHEROSCLEROSIS IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS R. Ivanova, C. Marinova, A. Alexiev, L. Mateva (Bulgaria) A. Teplov, A. Zotikov, A. Gritskevich, Z. Adyrkhaev, S. Pyanikin, I. Timina, I. Pyatkova, A. Kozhanova, A. Ivandaev, A. Pokrovsky (Russia) 077 912 N. Leach, S.C. Vesa, T. Alexescu, E. Dronca, V. Negrean, S. Dorel P. (Romania) R. Toro, I. Tinoco, B. Ruiz-Estevez, C. Rodriguez-Leal, E. Segura, N. Caro, C. Perez, I. Garcia, D. Gomez -Villarejo, M. Rodriguez-Rosety, M. Lagares, A. Mangas (Spain) EX VIVO ORGAN-PRESERVING SURGERY ON KIDNEYS FOR RENAL CELL CARCINOMA AND RENAL ARTERY ANEURYSMS APO-B48 IN PATIENTS WITH TYPE 2 DIABETES AND NON-ALKOHOLIC FATTY LIVER DISEASE B. Idzior-Waluś, M. Walus-Miarka, A. Trojak, P. Miarka, M. Kapusta (Poland) Y. Tanaka, M. Shimizu, N. Furusyo, Y. Kato, J. Hayashi (Japan) 076 911 A. Zotikov, A. Gritskevich, Z. Adyrkhaev, I. Timina, I. Pyatkova, V. Cigankov, A. Varava, A. Kozhanova, A. Ivandaev, M. Demina, A. Pokrovsky (Russia) Y. Liu, L. Hua-Long, W. Dengxuan, Z. Jianbin, C. Shiqun, D. Chong-Yang, C. Ping-Yan, T. Ning, C. Ji-Yan (China) 073 SURGICAL TREATMENT OF ANEURYSM AND ARTERIOVENOUS FISTULA OF RENAL ARTERIES EFFECTS OF BODY WEIGHT ON HEPATIC STEATOSIS IN ESSENTIAL HYPERTENSION919 C.H. Chou, W.C. Tsai (Taiwan) 090 910 HEPATIC STEATOSIS IS INDEPENDENTLY ASSOCIATED WITH ERECTILE DYSFUNCTION: ONE MORE LINK BETWEEN THE LIVER AND CARDIOVASCULAR RISK? 920 F. Rached, A. Laurinavicius, R. Conceição, R. Santos (Brazil) 147 Poster Walks – tuesday Board # Board # Dyslipidemias: Dyslipidemias, Screening and Treatment 101 091 PREVALENCE OF DIABETES MELLITUS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA921 S. Perez-Calahorra, R. Mateo-Gallego, N. Plana, J.P. Botet-Montoya, J.F. Ascaso, C. Lahoz, F. Almagro, R.M. Sánchez-Hernández, I. LamiquizMoneo, F. Civeira (Spain) 092 FAMILIAL HYPERCHOLESTEROLEMIA (FH) IN CHILDREN AND ADOLESCENTS: OPTIMIZATION OF DETECTION FOR EARLY TREATMENT 093 DIAGNOSTIC PERFORMANCE OF VARIOUS FAMILIAL HYPERCHOLESTEROLAEMIA CRITERIA COMPARED TO THE DUTCH LIPID CLINIC CRITERIA IN AN ASIAN POPULATION 094 103 104 RETROSPECTIVE OBSERVATIONAL STUDY ON THE DIAGNOSIS AND THERAPY OF THE FH ON A SAMPLE OF REAL WORLD POPULATION 105 096 INTERNATIONAL COMPARISON OF PRIMARY CARE KNOWLEDGE AND PRACTICES OF FAMILIAL HYPERCHOLESTEROLAEMIA (FH) 106 926 G.F. Watts (Australia) 097 INTERNATIONAL COMPARISON OF SERVICES AND FACILITIES FOR THE CARE OF FAMILIAL HYPERCHOLESTEROLAEMIA (FH) SWITCH TO ROSUVASTATIN VERSUS ADDITION OF EZETIMIBE IN PATIENTS RECEIVING ATORVASTATIN: EFFECT ON URINE 8-ISOPROSTANE LEVELS 107 927 CASCADE GENETIC SCREENING FOR FAMILIAL HYPERCHOLESTEROLEMIA IN WEST SIBERIA 108 928 929 LIPID CLINIC EXPERIENCE OF GENOTYPING FOR FAMILIAL HYPERCHOLESTEROLAEMIA930 K. Shipman, R. Cramb (United Kingdom) 148 FAMILIAL HYPERCHOLESTEROLAEMIA - GEOMAPPING OF THE BASELINE LDL LEVELS AND CHARACTERISATION OF LDL RECEPTOR MUTATIONS FOR PATIENTS DIAGNOSED IN THE NORTH WALES SCREENING PROGRAMME 2010-2015 936 ESTABLISHMENT OF A NATIONWIDE CASCADE SCREENING PROGRAM AND REGISTER FOR FAMILIAL HYPERCHOLESTROLEMIA IN GERMANY CARE HIGH 937 EPISODIC MEMORY PERFORMANCE IN YOUNG ADULTS WITH FAMILIAL HYPERCHOLESTEROLEMIA938 M. Mauri, N. Cuenca, R.M. Borrallo, E. Romero, J. Ottino, I. García-García, M.A. Jurado, M. Garolera (Spain) 109 E. Shakhtshneider, K. Makarenkova, D. Ivanoshchuk, P. Orlov, Y. Ragino, M. Voevoda (Russia) 100 CASE REPORT: HYPERCHOLESTEROLEMIC PATIENT WITH NEW HOMOZYGOUS LDLR MUTATION AND SEVERE EARLY CORONARY HEART DISEASE935 N. Schmidt, W. März, T. Grammer (Germany) E. Klouras, C. Tellis, F. Barkas, E. Liberopoulos, M. Elisaf, A. Tselepis (Greece) 099 934 M. De Soysa, R. Gingell, Y.P. Teoh (United Kingdom) G.F. Watts (Australia) 098 THE UK PAEDIATRIC FAMILIAL HYPERCHOLESTEROLAEMIA (FH) REGISTER: PRELIMINARY DATA T. Grenkowtiz, U. Kassner, N. Buchmann, N. El-Zidy-Ibrahim, D. Spira, I. Demuth, E. Steinhagen-Thiessen (Germany) 925 C. Garaffa, F. Natale, S. Sperlongano, F. Fimiani, M. Laringe, L. D'Acierno, E. Garaffa, G. Limongelli, G. Piccinocchi, P. Calabrò (Italy) 933 S. Humphries, J. Cooper, U. Ramaswami (United Kingdom) S. Sperlongano, C. Garaffa, F. Natale, F. Fimiani, E. Garaffa, L. D'Acierno, M. Laringe, G. Limongelli, G. Piccinocchi, P. Calabrò (Italy) 095 THE CT CORONARY CALCIUM SCORE IN FAMILIAL HYPERCHOLESTEROLAEMIA: COMPARISON BETWEEN PATIENTS WITH FH MUTATIONS AND THOSE WITH NO IDENTIFIED MUTATION S. Chaudhuri, M. Labib, A. Abeysekera (United Kingdom) 923 DUTCH SCORE AND “CASCADE SCREENING” FOR THE IDENTIFICATION OF PATIENTS AFFECTED BY HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA 924 SEVERE FAMILIAL HYPERCHOLESTEROLEMIA: PREVALENCE AND CHARACTERIZATION OF PATIENTS PRESENTING FOR CARDIAC CATHETERIZATION932 B. Zafrir, C. Shapira, G. Lavie, D.A. Halon, M.Y. Flugelman (Israel) 922 S. Abdul Razak, R. Rahmat, N.A. Mohd Kasim, T. Abdul Rahman, S. Muid, N. Mohd Nasir, Z. Ibrahim, S. Kasim, H. Nawawi (Malaysia) 931 M. Walus-Miarka, B. Idzior-Walus, D. Czarnecka, M. Kloch-Badełek, W. Wojciechowska, M. Kapusta (Poland) 102 E. De Faria (Brazil) CAROTID PLAQUES AND INTIMA-MEDIA THICKNESS - ARE THE SAME RISK FACTORS IN MEN AND WOMEN WITH FAMILIAL HYPERCHOLESTEROLEMIA? CARRIERS OF THE LDL RECEPTOR MUTATIONS WITHIN THE EXON 12 IN GENERAL POPULATION 939 J. Hubacek, A. Fellnerova, D. Dlouha, L. Schwarzova, V. Adamkova (Czech Republic) 110 TARGETED NEXT-GENERATION SEQUENCING OF THE LDLRAP1 GENE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA 940 D. Ivanoshchuk, E. Shakhtshneider, K. Makarenkova, P. Orlov, Y. Ragino, M. Voevoda (Russia) 149 Poster Walks – tuesday Board # 111 112 FH CLINICS - TWO SHORT YEARS OF EXPERIENCE Board # 941 I. Colaço, T. Vassalo, F. Faria, D. Cruz, J.L. Ducla Soares (Portugal) D374Y MUTATION IN THE PCSK-9 GENE IN TURKISH PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA: LONG TERM FOLLOW-UP WITH GOOD CLINICAL COURSE ACHIEVEMENT OF EUROPEAN ATHEROSCLEROSIS SOCIETY (EAS) TARGETS WITH LOMITAPIDE, A MICROSOMAL TRANSFER PROTEIN INHIBITOR IN HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLAEMIA (HOFH) 942 M. Kayıkcıoglu, E.K. Kocabas, A.T. VARDARLI, Z. EROGLU, H. DOKMEN, N. SALMAN, S. PAYZIN, L.H. CAN (Turkey) 122 H. Phillips, M. Ager, A. Hutchings (United Kingdom) 113 USING PERCENTILES TO DIAGNOSE FAMILIAL HYPERCHOLESTEROLEMIA IN PORTUGAL LOW-DENSITY LIPOPROTEIN GENE SCORE TO IDENTIFY POLYGENIC FORMS OF FAMILIAL HYPERCHOLESTEROLEMIA IN A SPANISH POPULATION 123 115 GENETIC ANALYSIS OF FAMILIAL HYPERCHOLESTEROLAEMIA IN IBEROAMERICAN COUNTRIES 124 IDENTIFICATION OF A NEW MUTATION IN THE N-TERMINAL REGION OF THE APOLIPOPROTEIN B GENE IN FAMILIAL HYPERCHOLESTEROLEMIA 945 125 126 946 PRELIMINARY RESULTS OF RUSSIAN FAMILIAL HYPERCHOLESTEROLEMIA REGISTRY947 127 CLINICAL CHARACTERISTICS OF COMMON PCSK9 GAIN-OFFUNCTION E32K VARIANT WITH HIGHER TG ELEVATION, AND DOUBLE HETEROZYGOTES WITH COMMON PCSK9 VARIANTS AND LDLR MUTATIONS 948 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 9 (PCSK9) V4I VARIANT WITH LDLR MUTATIONS MODIFIES THE PHENOTYPE OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA 128 HEREDITARY DEFECT OF APOLIPOPROTEIN B 100 - ANALYSIS OF GROUP OF PATIENTS TREATED WITH STANDARD PERORAL LIPID-LOWERING THERAPY IN ST. ANNE´S UNIVERSITY HOSPITAL BRNO O. Kyselak, V. Soska (Czech Republic) 150 CONSTRUCTION OF A NEW FAMILIAL HYPERCHOLESTEROLAEMIA VARIANT DATA BASE: A SYSTEMATIC REVIEW FOR A 2015 UPDATE 955 MOLECULAR BASIS OF FAMILIAL HYPERCHOLESTEROLEMIA IN POLAND – UPDATE FROM THE POLISH NATIONAL CENTRE OF DIAGNOSTICS AND TREATMENT OF FAMILIAL HYPERCHOLESTEROLEMIA 956 MORTALITY OF CARDIOVASCULAR DISEASE IN PATIENTS WITH GENETICALLY VERIFIED FAMILIAL HYPERCHOLESTEROLEMIA 957 HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HeFH) IN CHILDREN: AN ITALIAN EXPERIENCE 958 F. Guaraldi, M.D. Di Taranto, C. Giacobbe, G. Fortunato, O. Guardamagna (Italy) 129 949 130 950 GENETIC ANALYSIS OF FAMILIAL HYPERCHOLESTEROLEMIA IN MEXICO 959 A. Vazquez Cardenas, M.T. Magaña Torres, Y. Sanchez Lopez, T. Hernandez Flores, A.G. Colima Fausto, J.R. González Garcia, F. Escalante, D. Gonzalez Marines, C. Aguilar Salinas, M. Bourbon (Mexico) M. Hori, N. Ohta, A. Takahashi, M. Ogura, H. Makino, T. Tamanaha, Y. Miyamoto, M. Harada-Shiba (Japan) 120 954 K. Retterstøl, J. Igland, L. Ose, K.B. Holven, T.P. Leren, M.B. Veierød, L. Mundal (Norway) A. Nohara, M.A. Kawashiri, H. Tada, M. Yoshida, M. Mori, C. Nakanishi, K. Yagi, A. Inazu, M. Yamagishi, H. Mabuchi (Japan) 119 GENETIC EPIDEMIOLOGY OF ARH IN SICILY M. Chmara, M. Zuk, A. Mickiewicz, A. Brandt, K. Chlebus, J. Kubalska, J. Bautembach-Minkowska, M. Stroniawska-Woźniak, M. BednarskaMakaruk, L. Kłosiewicz-Latoszek, A. Rynkiewicz, M. Mysliwiec, M. Gruchala, J. Limon, B. Wasag (Poland) I.V. Sergienko, A.A. Ansheles, A.B. Popova, M.I. Voevoda, V.S. Gurevich, V.V. Henkel, V.V. Kukharchuk, M.V. Ezhov (Russia) 118 953 S. Azevedo, J.R. Chora, A.C. Alves, A.M. Medeiros, M. Bourbon (Portugal) M. Abifadel, S. Elbitar, Y. Ghaleb, G. Peloso, N. Stitziel, P. El Khoury, J.P. Rabes, V. Carreau, E. Bruckert, S. Kathiresan, M. Varret, C. Boileau (France) 117 FIRST PCSK-9 MUTANT PATIENT IN TURKEY R. Spina, V. Valenti, V. Ingrassia, M.P. La Spada, C. Scrimali, G. Misiano, D. Noto, O. Palesano, G.I. Altieri, V. Licata, F. Fayer, C.M. Barbagallo, A.B. Cefalù, M. Averna (Italy) J. Chora, P. Mata, R. Santos, A. Cárdenas Vázquez, M. Stoll, L. Schreier, A. Cuevas, A.C. Alves, A.M. Medeiros, L. Perez Isla, C. Jannes, A. Pereira, N. Dell'Oca, X. Reyes, P. Corral, V. Bañares, T. Magaña-Torres, C. AguilarSalinas, R. Alonso, M. Bourbon (Argentina) 116 952 E. Kaya Kocabas, M. Kayikcioglu, A. Tetik Vardarli, Z. Eroglu (Turkey) 944 J.M. Martín-Campos, J. Julve, N. Plana, R. Figueras, E. Esteve, M. Mauri, M. Bueno, A. Caixàs, E. Llargués, A. Vila, C. Morales, C. Soler, J. Argimón, J. Mayos, J. Grau, A. Zamora, L. Matas, L. Vila, L. Masana, F. Blanco-Vaca (Spain) ATHEROSCLEROSIS IN MONOGENIC FAMILIAL HYPERCHOLESTEROLEMIA VERSUS POLYGENIC HYPERCHOLESTEROLEMIA 951 M. Sharifi, A. Gallivan, D. Harvey, L. Ka Wah, J. Cooper, M. Futema, S.E. Humphries, D. Nair (United Kingdom) 943 A. Pereira, A.C. Alves, A.M. Medeiros, C. Mariano, M. Bourbon (Portugal) 114 121 35 YEARS OF EXPERIENCE WITH CHILDREN AFFECTED WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH): A CASE SERIES OF NINE PATIENTS 960 K. Widhalm, K. Derfler, G. Kostner, O. Helk (Austria) 151 Poster Walks – tuesday Board # Board # 131 141 PROGRAM STRATEGIES FOR FAMILIAL HYPERCHOLESTEROLEMIA IN URUGUAY961 M. Stoll, X. Reyes, N. Dell’Oca, F. Machado, A. Ressia, G. Fernandez, Zelarayán M(1) (Uruguay) 132 EFFECT OF APOE GENOTYPE ON LDL CHOLESTEROL LEVELS IN FH AND FDB PATIENTS: IS THERE SEX-SPECIFICALLY PROTECTIVE GENOTYPE? 133 GENETIC AND PHENOTYPIC CHARACTERIZATION OF LDLRECEPTOR IN PATIENTS WITH A CLINICAL DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA: TWO NOVEL MUTATIONS 142 134 THE R46L POLYMORPHISM OF PCSK9 GENE AND LIPID PROFILE IN CAUCASIAN POPULATION OF RUSSIA 143 135 144 FAMILIAL HYPERCHOLESTEROLAEMIA IN PRIMARY CARE: AWARENESS, KNOWLEDGE AND PRACTICES AMONG PRIMARY CARE DOCTORS IN MALAYSIA965 136 PERCEPTIONS ON HEALTH COMMUNICATION, SYMPTOMS AND CAUSES IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLAEMIA TREATED IN SPECIALIST CLINICS 137 CARDIOVASCULAR DISEASE RESEARCH BY USING DATA FROM ELECTRONIC HEALTH RECORDS 146 967 LDL APHERESIS IN CHILDREN WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: A CASE SERIES 968 I. Luirink, A. Wiegman, B. Hutten, J. Groothoff (Netherlands) 139 EVALUATION OF PLASMA-FED LIPID APHERESIS IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLAEMIA. 147 LOMITAPIDE IN HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA FIRST EXPERIENCES IN CLINICAL PRACTICE A. Vogt (Germany) 152 148 970 975 LONG-TERM TREATMENT WITH EVOLOCUMAB HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS: RESULTS FROM THE TRIAL ASSESSING LONG-TERM USE OF PCSK9 INHIBITION IN SUBJECTS WITH GENETIC LDL DISORDERS (TAUSSIG) 976 LIPID-LOWERING THERAPY AND TARGET ATTAINMENT AMONG HYPELIPIDEMIC INDIVIDUALS WITH OR WITHOUT FAMILIAL HYPERCHOLESTEROLEMIA: EVIDENCE FROM A LIPID CLINIC 977 F. Barkas, E. Klouras, T. Dimitriou, G. Liamis, E. Liberopoulos, M. Elisaf (Greece) 969 P. Downie, G. Bayly, L. Hart, S. Douglas, J. Griffin (United Kingdom) 140 CARDIOVASCULAR DISEASE IN HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA SUBJECTS ON STATIN TREATMENT E.A. Stein, T. Sampietro, R. Santos, M. Harada-Shiba, E. Bruckert, D. Blom, G.K. Hovingh, P. Couture, V. Blaha, M. Farnier, O. Descamps, H. Soran, S. Kasichayanula, J. Gibbs, C. Kurtz, L. Tang, N. Honarpour, S.M. Wasserman, F.J. Raal (South Africa) L. Majnaric, S. Sabanovic (Croatia) 138 ATTAINMENT OF LDL-C TREATMENT TARGET IN FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS: A THEORETICAL MODEL EXPLORING EFFICACY OF CURRENT AND NOVEL LIPID LOWERING THERAPIES974 V. Marco-Benedi, S. Perez-Calahorra, N. Plana, J.C. Pedro-Botet, J. Ascaso, C. Lahoz, F. Almagro, E. Ros, A. Brea, M. Suarez-Tembra, R.M. SanchezHernández, A. Vila Belmonte, F. Civeira (Spain) 966 N.A. Mohd Mokhsin, S. Abdul Razak, A.S. Ramli, M. Md Yasin, N.A. Mohd Kasim, S.S. Kasim, T. Rahman, H. Nawawi (Malaysia) 973 M.L. Hartgers, J. Besseling, G.K. Hovingh (Netherlands) 145 A.S. Ramli, N.A. Mohd Mokhsin, S. Abdul Razak, M. Md Yasin, Z. Ismail, N.A. Mohd Kasim, T. Rahman, H. Nawawi (Malaysia) FUNCTIONAL ANALYSIS OF MUTATIONS LOCATED IN THE LDL RECEPTOR SIGNAL SEQUENCE CODING REGION T. Freiberger, J. Pavlouskova, K. Reblova, L. Tichy, L. Fajkusova (Czech Republic) 964 K. Astrakova, E. Shakhtshneider, D. Ivanoshchuk, Y. Ragino, S. Astrakov, M. Voevoda (Russia) STUDY OF APOB MUTATIONS AND FAMILIAL HYPERCHOLESTEROLEMIA PHENOTYPES972 J. Bassani Borges, G. Medeiros Bastos, T.K. Almendros Afonso, E. Da Silva Rodrigues, H. Strelow Thurow, T. Dominguez Crespo Hirata, A. Arpad Faludi, R. Marques Gonçalves, R. Dominguez Crespo Hirata, M. Hiroyuki Hirata (Brazil) 963 C. Pavanello, C. Tarlarini, S. Penco, L. Calabresi, S. Castelnuovo, G. Mombelli, C. Sirtori (Italy) 971 I. Lamiquiz Moneo, M.R. Perez-Ruiz, E. Jarauta, M.T. Tejedor, L. Baila-Rueda, A.M. Bea, R. Mateo-Gallego, A. Cenarro, F. Civeira (Spain) 962 L. Schwarzova, A. Horinek, J. Hubacek, M. Vrablik, T. Freiberger, L. Tichy, H. Vaverkova, R. Ceska (Czech Republic) ANALYSIS OF CANDIDATE SINGLE NUCLEOTIDE VARIATIONS ASSOCIATED WITH POLYGENIC HYPERCHOLESTEROLEMIA IN FAMILIES WITH THE CLINICAL DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA INCIDENCE OF CARDIOVASCULAR DISEASE AMONG INDIVIDUALS WITH AND WITHOUT FAMILIAL HYPERCHOLESTEROLEMIA ATTENDING A LIPID CLINIC978 F. Barkas, E. Klouras, T. Dimitriou, G. Liamis, M. Elisaf, E. Liberopoulos (Greece) 153 Poster Walks – tuesday Board # Board # 149 158 CHANGES IN PLASMA LIPOPROTEIN SUBFRACTIONS IN PATIENTS WITH POLYGENIC HYPERCHOLESTEROLEMIA, FAMILIAL COMBINED HYPERLIPOPROTEINEMIA, AND FAMILIAL HYPERCHOLESTEROLEMIA AFTER ATORVASTATIN 150 PREVALENCE OF DYSLIPIDAEMIA AMONG ADULTS AGED 50-64 YEARS IN IRELAND: THE IRISH LONGITUDINAL STUDY ON AGEING (TILDA) C. Boot, E. Holmes, D. Neely, F. Jenkinson, H. Datta, L. Hughes (United Kingdom) 979 B. Muinjonov, E. Giyazitdinova (Uzbekistan) 159 980 C. Murphy, E. Shelley, T. Fahey, R.A. Kenny (Ireland) 151 IMPACT OF SOCIAL AND CLINICAL PARAMETERS ON NON-HDL CHOLESTEROL IN SCHOOL CHILDREN 152 STATIN PRESCRIPTION PATTERNS, ADHERENCE, AND ATTAINMENT OF CHOLESTEROL TREATMENT GOALS IN CLINICAL CARE IN ELDERLY WITH HYPERLIPIDEMIA AND CORONARY HEART DISEASE: A RUSSIAN OBSERVATION STUDY 160 153 STUDY OF THE PREVALENCE OF DYSLIPIDEMIAS IN CHILDREN AND ADOLESCENTS ATTENDED BY THE NATIONAL HEALTH SYSTEM IN CAMPINAS - SÃO PAULO - BRAZIL 161 154 162 CLINICAL MANAGEMENT AND QUALITY OF LIFE IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA UNDERGOING LIPIDAPHERESIS IN TURKEY: FIRST RESULTS OF A NATION-WIDE SURVEY (A-HIT REGISTRY)984 M. Kayıkcıoglu, L. Tokgozoglu, S. Pirildar, M. Yilmaz, L. Kaynar, M. Aktan, R. Durmus, A. Temizhan, O. Ozcebe, T. Akyol, H. Okutan, S. Sag, B. Altunkeser, M. Yenercag, E. Kurtoglu, S. Demircioglu, O. Salcioglu, M. Demir, H. Yilmaz, O. (Turkey) 155 FUNCTIONALLY CHARACTERIZATION OF LDLR MISSENSE ALTERATIONS FOUND IN CLINICAL FH PATIENTS GENETIC VARIANTS OF PCSK9 GENE IN CORONARY ARTERY DISEASE AMONG SOUTH INDIAN PATIENTS FAMILIAL COMBINED HYPERLIPIDEMIA IN CHILDREN: BIOCHEMICAL CHARACTERIZATION IN PEDIATRIC AGE F. Abello, E. Barabesi, A. Bosusco, O. Guardamagna, D. Vianello, A. Zambon (Italy) 991 CARDIOVASCULAR COMORBIDITIES LINKED TO OBESITY IN FORMER ATHLETES FROM TRANSYLVANIA 992 V. Negrean, O. Orășan, T. Alexescu, N. Leach, I. Para, M. Milaciu (Romania) 163 164 E_LIPID: CHARACTERIZATION OF THE LIPID PROFILE IN THE PORTUGUESE POPULATION993 SEVERE HYPERCHOLESTEROLEMIA IN HOSPITAL PRACTICE-SINGLE CENTRE EXPERIENCE IN SINGAPORE 994 S. Dissanayake, S.P. Li Tin, J.F. Choi Wan, M.S. Wong, S. Tavintharan (Singapore) 985 165 HIGH PREVALENCE OF FAMILIAL HYPERCHOLESTEROLEMIA IN ARGENTINA: RESULTS OF THE FIRST DETECTION PROGRAM. 995 P. Corral, G.I. López, A. Cristaldi, J.C. Tuseddo, L. Cacciagiú, G. Berg, L. Schreier (Argentina) 986 166 M. Ganesan (India) 157 HIGH TRIGLYCERIDES, LOW HDL CHOLESTEROL AND A LOW LDL CHOLESTEROL PER APOLIPOPROTEIN B RATIO PREDICT INCIDENT DIABETES IN PATIENTS WITH ESTABLISHED CORONARY ARTERY DISEASE C. Mariano, M. Antunes, Q. Rato, M. Bourbon (Portugal) A.C. Alves, S. Azevedo, A. Benito-Vicente, A. Etxebarria, P. Barros, A.M. Medeiros, C. Martin, M. Bourbon (Portugal) 156 SEARCHING FOR THE ELUSIVE FAMILIAL HYPERCHOLESTEROLAEMIA GENE MUTATIONS FOR INDEX PATIENTS - USING HISTORICAL LABORATORY LDL-C RESULTS IN PRIMARY CARE. A NORTH WALES EXPERIENCE.990 C. Saely, P. Rein, A. Vonbank, D. Zanolin, A. Leiherer, A. Muendlein, H. Drexel (Austria) 983 E. De Faria, E.I. Gomes, V.H. Zago, E.S. Parra, N.B. Panzoldo, G. Redezuk (Brazil) 989 Y.P. Teoh, R. Gingell (United Kingdom) 982 M. Bubnova, D. Aronov (Russia) TREATMENT OF THERAPY-REFRACTORY HYPERCHOLESTEROLEMIA WITH PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 ANTIBODIES (PCSK9-I) IN CARDIOVASCULAR HIGH RISK PATIENTS - EFFECTIVITY AND SAFETY IN CLINICAL ROUTINE T. Hollstein, D. Spira, N. Buchmann, N. El-Zidy Ibrahim, T. Bobbert, E. Steinhagen-Thiessen, U. Kassner (Germany) 981 A. Pereira, F. Guarnieri, A.P.Q. Mello, R. Santos Filho, T.L.R. Martinez (Brazil) VALIDATION OF SERUM ApoB/CHOLESTEROL AND ApoB/NON-HDL CHOLESTEROL RATIOS AS SCREENING TESTS FOR TYPE III HYPERLIPIDAEMIA 988 987 NETWORK ANALYSIS APPROACH TO FIND NEW CANDIDATE GENES AND PATHWAYS INVOLVED IN THE PATHOPHYSIOLOGY OF FAMILIAL HYPERCHOLESTEROLEMIA996 N. Rossi, M. Bourbon, F. Enguita (Portugal) 167 PARAMETRES OF ARTERIAL REMODELING IN FAMILAL HYPERCHOLESTEROLEMIA PATIENTS 997 V. Korneva, T. Kuznettsova (Russia) 154 155 Poster Walks – tuesday Board # Board # Dyslipidemias: Treatment 178 168 EFFECTS OF DIFFERENT DOSES OF ATORVASTATIN ON PLATELET AGGREGATION, ENDOTHELIAL FUNCTION, LEVELS OF SEROTONIN, ANGIOTENSIN II, BLOOD PRESSURE, CEREBRAL BLOOD FLOW IN HYPERTENSIVE PATIENTS WITH HYPERLIPIDEMIA EFFECT OF STATIN ON FASTING BLOOD SUGAR LEVEL; COMPARISONS OF KINDS OF STATINS AND ASSOCIATED PARAMETERS 998 179 999 DIFFERENT ROLE OF ACHIEVED LDL-CHOLESTEROL AND HS-CRP LEVEL IN FUTURE CARDIOVASCULAR DISEASE OUTCOMES IN NONPERCUTANEOUS CORONARY INTERVENTION PATIENTS WITH ONGOING STATIN THERAPY OF MODERATE INTENSITY 180 1000 M.H. Hyun, E. Lee, B.G. Choi, H.S. Seo, J.O. Na, C.U. Choi, H.E. Lim, J.W. Kim, S.W. Rha, E.J. Kim, C.G. Park, D.J. Oh (Republic of Korea) 171 172 181 173 COMPARISON OF LIPID MANAGEMENT BETWEEN ELDERLY AND NONELDERLY PATIENTS WITH AND WITHOUT CORONARY HEART DISEASE (CHD) 1002 STATIN ESCAPE PHENOMENON: DOES IT REALLY EXIST? EVIDENCE FROM A LIPID CLINIC EFFECTS OF LOW-DOSE VS. MODERATE-DOSE PITAVASTATIN ON LONGTERM CARDIOVASCULAR EVENTS IN KOREAN PATIENTS WITH CORONARY ARTERY DISEASE REQUIRING STENT IMPLANTATION: PROSPECTIVE, 3-YEAR FOLLOW-UP TRIAL 183 1003 GENE VARIANTS ASSOCIATED WITH STATIN-INDUCED MYOPATHY: DETERMINATION IN A CZECH POPULATION 184 1004 THE SAFETY OF STATINS IN PATIENTS WITH CHRONIC KIDNEY DISEASE ONE YEAR PERSISTENCE OF ATORVASTATIN AND AMLODIPINE FIXED DOSE COMBINATION VERSUS ATORVASTATIN THERAPY TESTOSTERONE UNDECANOATE IMPROVES LIPID PROFILE IN PATIENTS WITH TYPE 1 DIABETES AND HYPOGONADOTROPHIC HYPOGONADISM. RESULTS FROM TEST-T1D RANDOMIZED CLINICAL TRIAL. 1012 EFFECT OF TOCILIZUMAB ON CARDIAC BIOMARKERS HIGH-SENSITIVITY TROPONIN T AND NT-PROBNP IN RHEUMATOID ARTHRITIS: POST HOC ANALYSIS OF A RANDOMISED CONTROLLED TRIAL 1013 186 1006 CCAAT/ENHANCER BINDING PROTEIN DELTA CONTRIBUTES TO AN EARLIER PHASE OF PRO-INFLAMMATORY RESPONSE IN DOXORUBICIN RELATED CARDIOMYOPATHY 1014 EFFECT OF ENDOTOXIN AND NATURAL CAROTENOIDS ON AORTIC ENDOTHELIAL TIGHT JUNCTIONS´ OCCLUDIN EXPRESSION 1015 J. Krizak, K. Frimmel, E. Breierova, R. Sotnikova, J. Navarova, I. Bernatova, L. Okruhlicova (Slovakia) 1005 EFFECT OF DHA/EPA SUPPLEMENTATION ON ENDOTHELIAL DAMAGE MARKERS. THE BIOCLAIMS STUDY 1016 J. Góralska, M. Malczewska-Malec, U. Razny, A. Zdzienicka, A. Gruca, A. Chabowski, M. Sanak, A. Dembinska-Kiec, B. Solnica (Poland) Y.K. Cho (Republic of Korea) 177 1011 J.T. Wen, L.W. Hsu, P.Y. Liu (Taiwan) 185 J. Petrkova, L. Kocourkova, V. Zizkova, M. Taborsky, M. Petrek (Czech Republic) 176 THE EFFECTS OF ALIROCUMAB ON LDL CHOLESTEROL LEVELS IN PATIENTS RECEIVING STATINS P. Welsh, K. Tuckwell, N. Sattar (United Kingdom) D.S. Lim, H.J. Kim, Y.C. Kim, B.G. Kang, S.M. Jeon, S.J. Hong, J.Y. Cho, S.H. Lee, H.J. Joo, J.H. Park, C.W. Yu (Republic of Korea) 175 1010 J.J. Chillarón, J. Pedro-Botet, M. Fernández-Miró, M. Albareda, L. Vila, D. Benaiges, J.A. Flores Le-Roux (Spain) F. Barkas, E. Klouras, T. Dimitriou, M. Elisaf, E. Liberopoulos (Greece) 174 EFFICACY AND SAFETY OF FIXED-DOSE COMBINATION OF OLMESARTAN MEDOXOMIL AND ROSUVASTATIN IN KOREAN PATIENTS WITH HYPERTENSION AND DYSLIPIDEMIA H. Habibinejad (Iran) 182 N. Kume, R. Shimizu, H. Torii, D. Yasuda, Y. Hiraoka, T. Hashida (Japan) 1009 S.H. Kim, H.L. Lee, W.H. Lim, H.L. Kim, J.B. Seo, W.Y. Chung, J.H. Zo, M.A. Kim, H.S. Kim (Republic of Korea) COMPARISON THE EFFECT ON FASTING BLOOD SUGAR BETWEEN ATORVASTATIN, ROUSUVASTATIN AND PITAVASTATIN IN KOREAN POPULATION1001 Y.S. Lee, Y.W. Park, S.P. Hong, J.B. Lee, J.K. Ryu, J.Y. Choi, K.S. Kim (Republic of Korea) THE EFFICACY OF EVOLOCUMAB AND OTHER LIPID-LOWERING THERAPIES (LLT) FOR THE MANAGEMENT OF LOW DENSITY LIPOPROTEIN CHOLESTEROL (LDL-C): A SYSTEMATIC REVIEW AND NETWORK METAANALYSIS (NMA) G. Worthy, S.R. Gandra, I. Bridges, G. Worth, R. Dent, L.I. Cheng, C. Forbes, S. Deshpande, J. Ross, J. Kleijnen, E.S.G. Stroes (Netherlands) C.J. Kim, M.A. Kim (Republic of Korea) 170 1008 K. Kotula-Horowitz, M. Janczura, T. Iwaniec, R. Rosa, J. Zagjewski, T. Domagala (Poland) M. Bubnova, D. Aronov, E. Semenova (Russia) 169 IMPACT OF FENOFIBRATE THERAPY ON ENDOTHELIAL FUNCTION IN THE SUBJECTS WITH METABOLIC SYNDROME 1007 G. Simonyi, F. Tamás (Hungary) 156 157 Poster Walks – tuesday Board # Board # 187 197 IN VITRO PHARMACOLOGICAL EVALUATION OF MULTITARGET THROMBOXANE PROSTANOID RECEPTOR/ COX-2 AGENTS: A POSSIBLE STRATEGY TO SOLVE THE CARDIOVASCULAR ISSUES OF COXIBS 1017 M. Hoxha, C. Buccellati, V. Capra, C. Cena, A. Sala, M. Bertinaria, G. Rovati (Italy) 188 M. Eriksson, O. Ahmed, U. Gustafsson, K. Littman, S. Sahlin, C. Pramfalk, P. Parini (Sweden) THE USE OF N-ACETYLCYSTEINE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND DIASTOLIC LEFT VENTRICULAR DYSFUNCTION, IN ACCORDANCE WITH THE LEVEL OF HIGH-SENSITIVITY C-REACTIVE PROTEIN.1018 A. Nizomov, B. Toshev, J. Berdiqulov (Uzbekistan) 189 THREE TIMES A WEEK AND FIVE TIMES A WEEK WALKING EXERCISE FREQUENCIES ARE EQUALLY EFFECTIVE IN IMPROVING WALKING CAPACITY IN EXPERIMENTAL PERIPHERAL ARTERY DISEASE 198 SONODYNAMIC THERAPY OF THE RABBIT CAROTID ARTERY NEOINTIMAL HYPERPLASIA USING LOW- LEVEL COMBINED ELECTROHYDRAULIC SHOCK WAVES AND ULTRASONIC WAVES ACCOMPANIED BY PROTOPORPHYRIN IX ADMINISTRATION 199 1019 1020 H. Mehrad, B. Mahvi (Iran) 191 A NOVEL COMPOUND (D-47), THE HYPOLIPIDEMIC EFFECTS AND THE MECHANISM IN AN ANIMAL MODEL OF HYPERCHOLESTEROLEMIA (WHHLMI RABBIT) 192 193 Dyslipidemias: Coagulation 201 NOVEL ROLE OF BERBERINE IN LOX1-MEDIATED ENDOTHELIAL DYSFUNCTION 1022 A. Cicero, C. Caliceti, P. Rizzo, R. Ferrari, F. Fortini, G. Aquila, J. Shehu, E. Leoncini, L. Zambonin, B. Rizzo, M. Guardigli, A. Roda, S. Hrelia (Italy) R. Somerville, K. Viljoen, S. McKey, A. Shrivastava, J. Mehegan, R. Segurado, C. Murrin, C. Kelleher (Ireland) 1023 202 DOWN-REGULATION OF THE CHEMOKINE (C-C MOTIF) RECEPTOR 9 (CCR9) CONTRIBUTES TO THE ATHEROSCLEROSIS-LOWERING ACTIVITY OF THE ANGIOTENSIN-CONVERTING ENZYME INHIBITOR CAPTOPRIL INCIDENCE OF VALVULAR HEART DISEASE AFTER COMBINATION OF DOPAMIN AGONISTS WITH STATINS 203 1024 HYPOLIPIDEMIC EFFECT OF RHEOPHERESIS AND RESTORATION OF RETINAL PHOTORECEPTOR JUNCTION 1032 PLATELET-ASSOCIATED TISSUE FACTOR AS A NEW MECHANISM INVOLVED IN THE PROTHROMBOTIC PHENOTYPE OF STABLE ANGINA PATIENTS WITH TYPE-2 DIABETES MELLITUS (T2DM) 1033 L. Rossetti, P. Canzano, M. Mapelli, D. Trabattoni, F. Santilli, G. Davì, A. Lualdi, E. Tremoli, M. Camera (Italy) 1025 E. Giyazitdinova, B. Muinjonov, G. Rakhimbayeva, Y. Musayeva (Uzbekistan) 196 ADJUSTING FOR THE INFLUENCE OF THE HEMATOCRIT LEVEL IMPROVES THE PROGNOSTIC VALUE OF THE VERIFYNOW P2Y12 ASSAY 1031 J.W. Suh, Y.G. Kim, Y.S. Cho, T.J. Youn, I.H. Chae (Republic of Korea) J. Abd Alla, A. Langer, U. Quitterer (Switzerland) 195 PLASMA ADVANCED OXIDIZED PROTEIN PRODUCTS PROMOTE PLATELETENDOTHELIAL CROSSTALK AND ENDOTHELIAL TISSUE FACTOR EXPRESSION1030 G. Marsche, A. Heinemann, L. Pasterk (Austria) 1021 A. Pokrovskiy, A. Zotikov, V. Kulbak, E. Burtceva (Russia) 194 STATIN THERAPY REDUCES PHOSPATE LEVELS IN DIALYSIS PATIENTS: RESULTS FROM THE EPIDEMIOLOGICAL VITAMIN K ITALIAN STUDY (VIKI STUDY)1029 PLASMA FIBRINOGEN IS AN IMPORTANT CLINICAL MARKER FOR PROSPECTIVE ALL-CAUSE MORTALITY IN THE LIFEWAYS CROSSGENERATION COHORT STUDY EXPERIENCE OF TAKAYASU`S ARTERITIS SURGICAL TREATMENT 1028 C. Panzavolta, L. Benvegnù, A. Aghi, M. Biolo, S. Giannini, M. Noale, G. Tripepi, M. Plebani, N. Veronese, P. Messa, M. Rossini, M. Gallieni, S. Sella, F. Fabris, E. Manzato, L. Previato, S. Bertocco, A. Zambon, M. Fusaro, S. Zambon (Italy) 200 S. Tamura, Y. Yu, T. Nakagawa, R. Nagasaka, T. Tsunoda, K. Ogawa, M.O. Tori, T. Koike, M. Shiomi (Japan) CROSS-CLASS SERINE PROTEASE INHIBITOR SERP-2 BLOCKS LIVER ISCHEMIA REPERFUSION INJURY S. Ambadapadi, H. Chen, J. Fuentes, S. Morshed, J. Davids, B. Marques, A. Lucas (USA) M. Pellegrin, J. Lavier, K. Bouzourene, L. Mazzolai (Switzerland) 190 REMNANT CHOLESTEROL REDUCTION BY EZETIMIBE AND SIMVASTATIN DOES NOT AFFECT BILIARY LIPID CONCENTRATION IN GALLSTONE PATIENTS1027 1026 204 IMPACT OF TYPE-2 DIABETES MELLITUS (T2DM) ON THE PLATELET TRANSCRIPTOME PROFILE IN STABLE ANGINA (SA) PATIENTS 1034 L. Rossetti, M. Brambilla, P. Canzano, L. Piacentini, E. Bono, M. Mapelli, D. Trabattoni, A. Lualdi, G. Colombo, E. Tremoli, M. Camera (Italy) M. Blaha, E. Rencova, H. Langrova, M. Lanska, A. Stepanov, V. Blaha (Czech Republic) 158 159 Poster Walks – tuesday Board # Board # 205NTEGRIN αΙΙbβ3 AS POTENTIAL BIOMARKER OF HIGH ON-TREATMENT PLATELET REACTIVITY TO CLOPIDOGREL IN PATIENTS WITH AN ACUTE CORONARY SYNDROME 214 1035 A. Gkourogianni, M. Tsoumani, I. Ntallas, D. Tsoukatos, I. Goudevenos, A. Tselepis (Greece) 206 THE COMBINATION OF N-ACETYLCYSTEINE WITH FIBRINOLYTIC THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME. 215 1036 216 FEASIBILITY OF TARGETING THROMBUS USING FOCUSEDELECTROHYDRAULIC SHOCK WAVES ACCOMPANIED BY SIMULTANEOUSLY B-MODE ULTRASOUND IMAGING IN THE RABBIT MODEL OF COMMON CAROTID ARTERY ATHEROTHROMBOTIC OCCLUSION1037 NON-INVASIVE TREATMENT OF THE RABBIT CAROTID ARTERY ATHEROTHROMBOTIC OCCLUSION USING COMBINED Nd:YAG LASER AND PULSED- FOCUSED ULTRASOUND ACCOMPANIED BY THROMBOLYTIC AGENT ADMINISTRATION PROTHROMBOTIC PHENOTYPE IN HYPERTENSION: CONTRIBUTION OF MEGAKARYOCYTE- AND PLATELET-ASSOCIATED TISSUE FACTOR EXPRESSION IN STROKE-PRONE RATS 217 SILENCING ANTICOAGULANT PROTEIN C CAUSES SPONTANEOUS ATHEROTHROMBOSIS IN APOE KNOCKOUT MICE VASCULAR AGE - A HELPFUL TOOL IN ASSESSING CARDIOVASCULAR RISK 1046 REMOTE ISCHEMIC PRECONDITIONING AND ENDOTHELIAL FUNCTION IN HEALTHY VOLUNTEERS 1047 N. Ryazankina, M. Vagida, V. Manchurov, A. Lebedeva, A. Arakelyan, J.C. Grivel, L. Margolis, E. Vasilieva, A. Shpektor (Russia) 218 1038 THE ENDOTHELIAL FUNCTION IMPROVEMENT ON STATIN THERAPY IN TYPE 2 DIABETES ASSOCIATED WITH TNFα G(308)A AND G(238)A POLYMORPHIC MARKERS 1048 N. Lebedeva, O.K. Vikulova, A.G. Nikitin, M.S. Shamkhalova, M.V. Shestakova (Russia) 1039 219 M. Brambilla, P. Gelosa, L. Rossetti, L. Castiglioni, P. Canzano, S. Luigi, E. Tremoli, M. Camera (Italy) 210 1045 A. Dumitrescu, S. Mosteoru, L. Gaita, R. Pleava, D. Gaita (Romania) H. Mehrad, A. Akrami (Iran) 209 THE PROGNOSTIC IMPORTANCE OF ENDOTHELIAL DYSFUNCTION IN METABOLIC SYNDROME WITH CORONARY ARTERY DISEASE T. Ueda (Japan) H. Mehrad (Iran) 208 1044 N. Burko, L. Salyamova, Y. Tomashevskaya, V. Oleynikov (Russia) A. Nizomov (Uzbekistan) 207 INFLUENCE OF CARBOHYDRATE METABOLISM DISORDERS ON STRUCTURAL AND FUNCTIONAL PROPERTIES OF THE LARGE ARTERIES IN PATIENTS WITH TYPE 2 DIABETES MELLITUS BENEFICIAL EFFECT OF AZILSARTAN AND AMLODIPINE ON ENDOTHELIAL FUNCTION IN HYPERTENSIVE PATIENTS 1049 T. Nishida, M. Ayaori, K. Shiotani, H. Uto-Kondo, M. Sasaki, T. Komatsu, Y. Endo, M. Ito, M. Ishizuka, M. Sakurada, K. Ikewaki (Japan) 1040 220 A.B. Ouweneel, M. Heestermans, R.A.F. Verwilligen, M. Van Eck, B.J.M. Van Vlijmen (Netherlands) CIRCULATING PROGENITOR CELLS IN HYPERTENSIVE SUBJECTS: EFFECTIVENESS OF A TREATMENT WITH OLMESARTAN IN IMPROVING CELL NUMBER AND MIRS PROFILE BESIDES EXPECTED PHARMACOLOGICAL EFFECTS 1050 G. Mandraffino, C.O. Aragona, E. Imbalzano, V. Cairo, F. Mamone, M.A. Sardo, A. Saitta (Italy) Dyslipidemias: Endothelial Dysfunction 211 LOW-FLOW MEDIATED CONSTRICTION INCORPORATED INDICES AS INDICATORS OF CARDIOVASCULAR RISK IN SMOKERS 1041 221 N. Norioka, Y. Takemoto, M. Kobayashi, A. Makuuchi, J. Yoshikawa, Y. Yamazaki, Y. Kamiyama, T. Shuto, M. Yoshiyama (Japan) 212 ENDOTHELIAL SHEAR RATE IN PATIENTS WITH CAROTID ATHEROSCLEROSIS 1042 V. Genkel, A. Salashenko, O. Alekseeva, M. Denisenko, I. Shaposhnik (Russia) 213 Genetics, Nutrition, Biomarkers: Genetics, Gene Regulation ANALYSIS OF BIOLOGICAL, STRUCTURAL AND FUNCTIONAL MARKERS OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH ARTERIAL HYPERTENSION, TREATED WITH ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS 1051 P. Downie, G. Bayly (United Kingdom) 222 1043 A CASE OF SEVERE CHYLOMICRONAEMIA SYNDROME, IN A PATIENT WITH NORMAL LIPOPROTEIN LIPASE ACTIVITY, DUE TO A PREVIOUSLY UNIDENTIFIED MUTATION IN THE GPIHBP1 GENE MOLECULAR ANALYSIS OF GENES INVOLVED IN LIPOPROTEIN LIPASE DEFICIENCY IN SLOVAK PATIENTS WITH FAMILIAL CHYLOMICRONEMIA 1052 D. Gabcova, D. Stanikova, M. Huckova, V. Bzduch, J. Stanik, I. Klimes, K. Raslova, D. Gasperikova (Slovakia) M. Andor, V. Buda, C. Cristescu, M. Voicu, L. Suciu, C. Muntean, M. Tomescu (Romania) 160 161 Poster Walks – tuesday Board # 223 DISSECTION OF CLINICAL AND GENE EXPRESSION SIGNATURES OF FAMILIAL VS MULTIFACTORIAL CHYLOMICRONEMIA Board # 234 1053 D. Gaudet, D. Brisson, K. Tremblay (Canada) 224 225 A NOVEL HOMOZYGOUS MUTATION IN GPD1 LEADING TO SEVERE HYPERTRIGLYCERIDEMIA1054 THE GG GENOTYPE OF VITAMIN D METABOLISM-RELATED GENE DHCR7 rs12785878 IS MORE PREVALENT IN THE INDIANS AND ASSOCIATED WITH HIGHER OXIDATIVE STRESS INDEX IN SINGAPORE IDENTIFICATION AND CHARACTERIZATION OF TWO NOVEL MUTATIONS IN THE LPL GENE CAUSING TYPE I HYPERLIPOPROTEINEMIA R. Dalan, H. Liew, L.L. Goh, X. Gao, D. Chew, B.O. Boehm (Singapore) STATINS UPREGULATE microRNA-122 IN HepG2 CELLS 227 THE HYPERTRIGLYCERIDEMIC EFFECT OF APOC3 3'UTR VARIANT SST1 IS NOT MEDIATED BY A HEPATIC OR INTESTINAL MIRNA REGULATION 235 1055 236 237 1057 PLASMA LIPOPROTEINS OF PATIENTS WITH GENETIC LAL DEFICIENCY ARE ENRICHED IN CHOLESTERYL ESTERS: RELEVANCE OF CHOLESTEROL ESTERIFICATION BY LCAT 238 1058 M. Gomaraschi, L. Arnaboldi, F. Abello, C. Pavanello, F. Zimetti, E. Favari, L. Calabresi, O. Guardamagna (Italy) 229 LYSOSOMAL ACID LIPASE DEFICIENCY IN GREECE: A RARE INBORN ERROR OF METABOLISM PRESENTING WITH DYSLIPIDAIMIA AND LIVER DISEASE 230 WILL FAMILIAL HYPERCHOLESTEROLAEMIA COHORTS HIDE MANY MORE LISOSOMAL ACID LIPASE DEFICIENCY PATIENTS? 1059 231 SCREENING OF LYSOSOMAL ACID LIPASE DEFICIENCY IN PATIENTS WITH SEVERE DYSLIPIDEMIA AND PREMATURE CORONARY HEART DISEASE 232 GENETIC VARIANTS OF ABO BLOOD GROUP WITH CORONARY ARTERY DISEASE AMONGST INDIANS 241 1061 GPER P.P16L POLYMORPHISM IS NOT ASSOCIATED WITH ALTERED LIPID PHENOTYPES AND CIMT PROGRESSION- A PLIC STUDY 242 1062 A. Dhyani, A. Baragetti, K. Garlaschelli, F. Pellegatta, L. Grigore, D. G.Norata, A.L. Catapano (Italy) 162 1069 GENETIC DETERMINATION OF THE ATHEROSCLEROTIC PLAQUE STABILITY 1070 MAY THE TRANSCRIPTIONAL ACTIVITY OF TRANSFORMING GROWTH FACTOR BETA 1 GENE BE A MARKER FOR EARLY STAGES FOR CORONARY ATHEROSCLEROSIS?1071 ASSOCIATION OF SERUM CAROTENOID CONCENTRATION WITH SINGLE NUCLEOTIDE POLYMORPHISMS IN APOE, BCMO1, NPC1L1, CD36, GSTP1, ABCG5, FABP1, FABP2 AND LIPC GENES1072 A. Mazeikiene, D. Karciauskaite, N. Burokiene, Z. Daunoravicius, Z.A. Kucinskiene, V. Kucinskas (Lithuania) 243 1063 PHENOTYPE OF VULNERABLE ATHEROSCLEROTIC PLAQUES SHOWS STRONG ASSOCIATION WITH SINGLE NUCLEOTIDE POLYMORPHISM ALLELES OF COMMON RISK VARIANTS FOR CORONARY ARTERY DISEASE J. Dąbek, M. Bałys, J. Piotrkowicz, J. Głogowska-Ligus, Z. Gąsior (Poland) P. Chawla, T. Ashavaid, C. Ponde, R. Rajani, A. Deshpande, R. Sawant (India) 233 1068 I. Goncharova, M. Golubenko, O. Makeeva, V. Kashtalap, N. Tarasenko, A. Markov, V. Puzyrev (Russia) 1060 O. Azevedo, N. Marques, H. Antunes, P. Azevedo, M. Oliveira, D. Bento, J. Guedes, B. Marmelo, R. Faria, E. Correia (Portugal) Rs6922269 MARKER AT THE MTHFD1L GENE PREDICT CARDIOVASCULAR MORTALITY IN MALES AFTER ACUTE CORONARY SYNDROME R. Furtmair, C. Kuehn, C. König, A. Ekici, L. Klinghammer, S. Achenbach, A. Reis, M. Tauchi, B. Dietel (Germany) 240 J.R. Chora, A.C. Alves, A.M. Medeiros, C. Mariano, G. Loubarinhas, A. Guerra, H. Mansilha, M. Bourbon (Portugal) SINGLE NUCLEOTIDE POLYMORPHISMS AT THE HYDROXY-METHYLGLUTARYL-COA REDUCTASE GENE LOCUS SIGNIFICANTLY PREDICT CARDIOVASCULAR EVENTS IN CORONARY PATIENTS WITH TYPE 2 DIABETES 1067 J. Hubacek, V. Stanek, R. Poledne, V. Adamkova, J. Pitha (Czech Republic) 239 E. Drogari, V. Mollaki, H. Christomanou, K. Stamatelopoulos, N. Manolaki (Greece) 1066 A. Leiherer, A. Muendlein, C. Saely, E. Kinz, P. Rein, A. Vonbank, P. Fraunberger, H. Drexel (Austria) M. Dancer, C. Marcais, C. Caussy, M. Di filippo, P. Moulin, S. Charrière (France) 228 ASSOCIATION OF THE HETEROPLASMY LEVEL OF MUTATION IN GENE MT-CYB WITH CAROTID ATHEROSCLEROSIS IN WOMEN 1065 V. Sinyov, M. Sazonova, M. Chicheva, N. Nikitina, I. Sobenin, A. Orekhov (Russia) 1056 A. Etxebarria, X. Moreno, A. Benito-Vicente, S. Jebari, U. Galicia, H. Ostolaza, C. Martin (Spain) 1064 T. Chia-Yin, C. Hung-Yi, H. Fang-I (Taiwan) J. Levels, R. Piña-Aguilar, J. Peter, G.M. Dallinga-Thie (Netherlands) P. Pingitore, S.M. Lepore, C. Pirazzi, R.M. Mancina, B.M. Motta, L. Valenti, K.E. Berge, K. Retterstøl, T.P. Leren, O. Wiklund, S. Romeo (Sweden) 226 NFE2L2 RS2364723 CC GENOTYPE SIGNIFICANTLY INCREASED THE RISK OF CARDIOVASCULAR DISEASE: A CASE-CONTROL STUDY IN AN ARSENIASIS-ENDEMIC AREA IN TAIWAN A TOOL FOR QUANTITATIVE MEASUREMENT OF PROATHEROGENIC HETEROPLASMIC MUTATIONS OF MITOCHONDRIAL DNA 1073 I. Sobenin, K. Mitrofanov, A. Orekhov (Russia) 163 Poster Walks – tuesday Board # Board # 244 253 CREATION OF CYBRID LINES OF MONOCYTE ORIGIN WITH HIGH HETEROPLASMY LEVEL FOR MITOCHONDRIAL GENOME MUTATION M.1555G>A1074 M. Sazonova, V. Sinyov, A. Ryzhkova, T. Shkurat, N. Demakova, N. Nikitina, I. Sobenin, A. Orekhov (Russia) 245 DETECTION OF THRESHOLD HETEROPLASMY LEVEL OF mtDNA IN LYPOFIBROUS PLAQUES OF HUMAN AORTIC INTIMA PROATHEROGENIC MUTATIONS OF MITOCHONDRIAL DNA IN PATIENTS WITH METABOLIC SYNDROME 1075 MITOCHONDRIAL DNA MUTATIONS ASSOCIATED WITH CAROTID ATHEROSCLEROSIS: NGS DATA 255 1076 ROLES OF ORPHAN NUCLEAR RECEPTORS IN CARDIAC HYPERTROPHY 1077 ROLE OF GENETIC POLYMORPHISMS AT THE ADIPONECTIN GENE IN REGULATION OF ADIPONECTIN GENE EXPRESSION AND CIRCULATING ADIPONECTIN LEVELS 257 1078 1085 DNA METHYLATION AND COPY NUMBER EVENTS IN ATHEROSCLEROTIC LESIONS1086 GENE THERAPY: CASE STUDY ON THE FIRST LIPOPROTEIN LIPASE DEFICIENCY PATIENT TREATED WITH ALIPOGENE TIPARVOVEC IN GERMANY 1087 U. Kassner, T. Hollstein, M. Wühle-Demuth, I. Demuth, E. SteinhagenThiessen (Germany) 258 1079 L. Kedenko, W. Patsch, I. Kedenko, S.M. Patsch, S. Coassin, F. Kronenberg, F. Krempler, B. Paulweber, C. Lamina (Austria) 250 ENDOTOXIN STRESS-INDUCED APOLIPOPROTEIN E GENE DOWNREGULATION IN MACROPHAGES IS REDUCED BY METFORMIN M. Nazarenko, A. Markov, A. Sleptcov, I. Lebedev, N. Skryabin, O. Barbarash, V. Puzyrev (Russia) G.H. Eom, D.H. Kwon, S. Shin, Y.U. Lee, E. Kim, N. Choe, Y.S. Nam, H. Kook (Republic of Korea) 249 1084 E.V. Fuior, S. Stavri, V.G. Trusca, I.F. Tudorache, M. Simionescu, D. Kardassis, A.V. Gafencu (Romania) 256 I. Sobenin, A. Zhelankin, Z. Khasanova, V. Orekhova, A. Orekhov, A. Postnov (Russia) 248 DOES THE GENE EXPRESSION OF NUCLEAR FACTOR KAPPA B IN PATIENTS WITH EARLY STAGES OF CORONARY ATHEROSCLEROSIS DIFFERS FROM HEALTHY INDIVIDUALS J. Dąbek, M. Bałys, J. Głogowska-Ligus, J. Piotrkowicz, Z. Gąsior (Poland) I. Sobenin, M. Sazonova, V. Orekhova, A. Zhelankin, A. Orekhov, A. Postnov (Russia) 247 1083 E. Coskunpinar, H.A. Cakmak, A.K. Kalkan, N. Ozan Tiryakioglu, T. Araz, Z. Ongen (Turkey) 254 A. Ryzhkova, M. Sazonova, V. Sinyov, E. Galitsyna, V. Barinova, N. Nikitina, I. Sobenin, A. Orekhov (Russia) 246 IS PLASMA MICRORNA-1909-5p A NEW POTENTIAL BIOMARKER FOR ACUTE MYOCARDIAL INFARCTION MAJOR ADIPOKINES AND -420 C>G RESISTIN GENE POLYMORPHISHM AS PREDICTORS OF ACUTE ISCHEMIC STROKE SEVERITY AND IN-HOSPITAL OUTCOME1088 S. Bouziana, K. Tziomalos, A. Goulas, T.A. Vyzantiadis, A. Panderi, A. Hatzitolios (Greece) LOW LDL-CHOLESTEROL, PCSK9 AND HMGCR GENETIC VARIATION, AND RISK OF NEURODEGENERATIVE DISEASE: A MENDELIAN RANDOMIZATION STUDY1080 259 PPAR-ALPHA GENE HAPLOTYPES, ARSENIC EXPOSURE AND RISK OF CARDIOVASCULAR DISEASE 1089 F.I. Hsieh, S.H. Lin, C.F. Huang, H.Y. Chiou (Taiwan) M. Benn, B. Nordestgaard, R. Frikke-Schmidt, A. Tybjærg-Hansen (Denmark) 251 252 RELATIONSHIP BETWEEN CIRCULATING microRNA-30c WITH LIPOPROTEINS, THEIR CIRCULATORY TRAFFICKING AND EFFECT OF STATINS 1081 Genetics, Nutrition, Biomarkers: Nutrition R. Sodi, J. Eastwood, L. Denby, I. Godber, M. Caslake, C.J. Packard (United Kingdom) 260 HYPERGLYCEMIA INCREASES MICRORNAS IN CIRCULATING HDL FROM ACUTE CORONARY SYNDROME PATIENTS AND MODULATES MIRNA PROCESSING MACHINERY IN HUMAN MACROPHAGES L.S. Niculescu, N. Simionescu, G.M. Sanda, M.G. Carnuta, C.S. Stancu, A.C. Popescu, R.M. Popescu, A. Vlad, D.R. Dimulescu, M. Simionescu, A.V. Sima (Romania) 164 ABNORMAL BALGHAM MUNZIQ, A UIGHUR HERBAL MEDICINE FORMULA, HAS BEEN RECENTLY SHOWN TO POSSESS EXTENSIVE CARDIOVASCULAR PHARMACOLOGICAL ACTIVITIES 1090 D. Xilifu, A. Nurmuhammat, U. Halmurat (China) 1082 261 EFFECTS OF RAMADAN FASTING ON BIOLOGICAL PARAMETERS IN PATIENTS WITH CARDIOVASCULAR RISK FACTORS 1091 K. Bouzid, W. Hmaidi, Y. Molahedh, H. Ben Ahmed, A. Bartkiz, H. Baccar, J. Abdelmoula (Tunisia) 165 Poster Walks – tuesday Board # 262 INCREASING ADHERENCE OF CONSUMERS TO DIET & LIFESTYLE CHANGES TO LOWER (LDL) CHOLESTEROL: THE ACT STUDY Board # 272 1092 T.E. SIALVERA, P. Farajian, E.A. Trautwein, A. Papadopoulou, S. Efstathiou, G. Goumas, I. Dimakopoulos, K. Papavasiliou, A. Koutsouri, A. Zampelas (Greece) 263 NUTRITIONAL MODULATION OF THE TOXICITY OF ENVIRONMENTAL POLLUTANTS: IMPLICATIONS IN ATHEROSCLEROSIS DIETARY POLYUNSATURATED FATTY ACID AND FRAMINGHAM RISK SCORE : ANALYSIS OF THE KOREA NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY (KNHAENS 2013) 1093 273 VITAMIN D STATUS AND BIOMARKERS OF ENDOTHELIAL ACTIVATION IN OBESE INDIVIDUALS 274 1094 EFFECTS OF VITAMIN E OR LIPOIC ACID SUPPLEMENTATION ON FASTING OXYPHYTOSTEROL CONCENTRATIONS IN SUBJECTS WITH IMPAIRED GLUCOSE TOLERANCE OR TYPE II DIABETES 1095 275 276 EFFECTIVENESS OF A LOW GLYCEMIC INDEX SOLUBLE PLANT POWDER, AS A LOW-CALORIE REPLACEMENT MEAL, IN OVERWEIGHT AND OBESE PATIENTS1097 SUSTAINED NUTRITIONAL COUNSELING IMPROVES DIETARY INTAKE IN PARENTS AND THEIR CHILDREN OVER 5 YEARS: THE PEP FAMILY HEART STUDY1098 P. Schwandt, E. Liepold, M. Heinzel-Gutenbrunner, T. Bertsch, G.M. Haas (Germany) 269 SPANISH OBESE CHILDREN AND BIOCHEMICAL PARAMETERS : NONHEALTHY NUTRITIVE PATTERNS LONG-TERM MAGNESIUM SUPPLEMENTATION IMPROVES ARTERIAL STIFFNESS IN OVERWEIGHT AND OBESE ADULTS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED INTERVENTION STUDY 1099 271 THIRTEEN YEAR FOLLOWUP OF MANAGING PATIENTS WITH KNOWN CORONARY ARTERY DISEASE USING A LECTIN-LIMITED, HIGH DOSE OLIVE OIL AND POLYPHENOL RICH DIET 1105 PLASMA PLANT STEROLS AND PLANT STEROL INTAKE VARY ACROSS PLANT-BASED DIETARY PATTERNS AMONG ADULTS FROM NORTH AMERICA 1106 LOW-FAT DIETARY TREATMENT ENRICHED WITH SOY PROTEIN IN CHILDREN AFFECTED WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS FROM A RANDOMIZEDCONTROLLED PILOT STUDY 1107 ANGIOGRAPHIC AND ANTIOXIDANT CHANGES AFTER SUPPLEMENTATION WITH HERACLEUM PERSICUM EXTRACT: RESULTS OF A RANDOMIZED CONTROLLED TRIAL 1108 A. Sahebkar, Y. Panahi, H. Taghipour (Iran) 279 DO DIET AND EXERCISE INFLUENCE IN AN ATHLETIC POPULATION?: NEW CLUES OF THE ENTERO-INSULAR AXIS 1109 C. Rodriguez-Leal, V. Aragon, I. Tinoco-Racero, E. Segura, B. Ruiz-estevez, E. Sanchez-Orellana, C. Perez, M. Monsalvo Hernando, N. Caro, A. Perez, I. Garcia-Campanario, A. Mangas, R. Toro (Spain) 1100 280 P.J. Joris, J. Plat, S.J.L. Bakker, R.P. Mensink (Netherlands) HAZELNUT-ENRICHED DIET IMPROVES LIPID PROFILE, FATTY ACID COMPOSITION OF ERYTHROCYTES MEMBRANE AND MARKERS OF OXIDATIVE STRESS IN CHILDREN WITH PRIMARY DYSLIPIDEMIA: A RANDOMIZED CONTROL TRIAL O. Helk, K. Widhalm (Austria) 278 C. Rodriguez-Leal, B. Ruiz-Estevez, E. Segura, I. Tinoco-Racero, N. Caro, C. Perez, I. Garcia-Campanario, A. Perez, M. Quezada-Feijoo, A. Mangas, R. Toro (Spain) 270 1104 D. Luetjohann, K. Jaceldo-Siegl, R. Sirirat, E. Haddad (Germany) 277 R. Volpe, A. Bianco, F. Pacioni, E. Schiavetto (Italy) 268 PLASMA FAT-SOLUBLE VITAMIN AND CAROTENOID CONCENTRATIONS AFTER PLANT STEROL AND PLANT STANOL ESTER CONSUMPTION – A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS V. Deon, C. Del Bo', A. Bosusco, S. Vendrame, M. Porrini, P. Simonetti, O. Guardamagna, P. Riso (Italy) 1096 S. Baumgartner, R.P. Mensink, G. Haenen, A. Bast, C. Binder, O. Bekers, C. Husche, D. Lütjohann, J. Plat (Netherlands) 267 1103 S. Baumgartner, R. Ras, E. Trautwein, R.P. Mensink, J. Plat (Netherlands) B. Ilincic, E. Stokic, M. Djeric, N. Eremic, D. Popovic, Z. Stosic (Serbia) 266 PLANT STANOL SUPPLEMENTATION LOWERS CETP-MASS, BUT NOT CETP-ACTIVITY, IN HEALTHY SUBJECTS C. Talbot, J. Plat, A. Ritsch, R. Mensink (Netherlands) N.S. Joo, B. Choi, S.I. Jung (Republic of Korea) 265 1102 G. Chiva-Blanch, V. Bratseth, K. Laake, P. Myhre, H. Arnesen, S. Solheim, E. Berg-Schmidt, L. Badimon, I. Seljeflot (Spain) B. Hennig, M. Petriello (USA) 264 SERUM CONTENT OF OLEIC ACID IS ASSOCIATED WITH HIGHER PLATELET-, ENDOTHELIAL- AND LEUKOCYTE-DERIVED CIRCULATING MICROPARTICLES IN NORWEGIAN NORMOLIPIDEMIC ELDERLY PATIENTS AFTER AN ACUTE MYOCARDIAL INFARCTION EVALUATION OF ACTUAL CONSUMPTION OF PULSE REDUCING DRUGS IN PATIENTS AFTER ACUTE CORONARY SYNDROME 1110 T. Chudinovskikh, E. Tarlovskaya (Russia) 1101 S. Gundry, J. Epstein (USA) 166 167 Poster Walks – tuesday Board # 281 EFFECTS OF RAMADAN FASTING ON CLINICAL AND BIOCHEMICAL PARAMETERS FOR TYPE 2 DIABETICS Board # 291 1111 K. Bouzid, Y. Molahedh, W. Hmaidi, N. Mchirgui, A. Bartkiz, E. Talbi, N. Ben Abdallah, A. Bahlous, J. Abdelmoula (Tunisia) 282 COMPARISON OF EFFECTS OF DIABETIC ENTERAL NUTRITION AND STANDARD ENTERAL NUTRITION ON POSTPRANDIAL LEVEL OF GLYCEMIA, FREE FATTY ACIDS AND GLUCAGON-LIKE PEPTIDE-1. REGULATION OF HYPOTHALAMIC GENE EXPRESSION BY DNA METHYLATION IS INFLUENCED BY PARENTAL DIET DURING PREGNANCY AND LINKED TO OFFSPRING'S RISK OF OBESITY 292 INORGANIC NITRATE DOES NOT AFFECT GLUCOSE AND INSULIN REGULATION BUT LOWERS OXIDATIVE STRESS IN OBESE ADULTS DURING ACUTE HYPERGLYCAEMIA 1112 293 1113 EFFECT OF DIFFERENT ORAL GLUCOSE LOADS ON THE ANTIOXIDANT, INFLAMMATORY AND PLATELET RESPONSE OF HEALTHY VOLUNTEERS 294 1114 INCREASED BILE ACID AND CHOLESTEROL SYNTHESES AND PCSK9 IN MORBID OBESITY ARE RAPIDLY NORMALIZED FOLLOWING ACUTE CALORIC RESTRICTION 295 1115 SUPPRESSION OF DNA DAMAGE BY DIETARY SUPPLEMENT WHICH CONTAINS PLANT EXTRACTS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL 296 1116 IMPACT OF OIL AND PROTEINS DERIVED FROM ANTARCTIC KRILL ON ATHEROSCLEROSIS DEVELOPMENT IN APOEKO MICE THE IMPACT OF DIETARY SUPPLEMENTATION OF VERNONIA CALVOANA LEAVES ON SERUM LIPID PROFILE AND HAEMATOLOGICAL INDICES IN ALBINO WISTAR RATS 1124 FERULIC ACID FROM RICE BRAN ENZYMATIC EXTRACT IS RESPONSIBLE FOR ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES 1125 POTENTIAL PROTECTIVE EFFECTS OF DUNALIELLA SALINA ON DEHPINDUCED MMP-2 AND MMP-9 EXPRESSION VIA MAPK, ERK1/2, AKT, AND NF-κB PATHWAYS IN VASCULAR SMOOTH MUSCLE CELLS 1126 M.F. Shih, J.Y. Cherng (Taiwan) 297 298 1118 RiBOSE-CYSTEINE INCREASES GLUTATHIONE-BASED ANTIOXIDANT STATUS AND REDUCES ATHEROSCLEROSIS IN apoE-DEFICIENT MICE 1127 S. McCormick, T. Kader, C. Porteous, G. Jones, N. Dickerhof (New Zealand) 1117 L. Gavriil, C. Argyrou, I. Malagaris, E. Fragopoulou (Greece) 288 1123 C. Perez Ternero, B. Bermudez Pulgarin, A. Macia, M.J. Motilva, M.D. Herrera, M. Alvarez de Sotomayor (Spain) S. Straniero, F. Rosqvist, D. Edholm, M. Sundbom, U. Risérus, M. Rudling (Sweden) 287 LIQUID FRUCTOSE SUPPLEMENTATION IN WESTERN DIET-FED C57BL/6N MICE CAUSES LIVER CHOLESTEROL LOADING WITHOUT CHANGING CALORIE INTAKE AND BODY WEIGHT G. Egbung, I. Atangwho (Nigeria) A. Mikellidi, D. Papadopoulou - Pozatzidou, E. Bachti, C. Xenaki, S. Antonopoulou, C. Demopoulos, T. Nomikos (Greece) 286 1122 M. Baena, G. Sangüesa, M. González, M. Alegret, N. Roglans, J.C. Laguna (Spain) A. Ashor (United Kingdom) 285 LOW-SALT DIET INDUCES ATHEROSCLEROSIS INDEPENDENT OF LOWERING BLOOD PRESSURE IN HYPERTENSIVE MICE S. Catanozi, F. Fusco, D. Gomes, K. Bispo, V. Toledo, D. Barbeiro, V. Capelozzi, L. Furukawa, A.P. Velosa, W. Teodoro, J. Heimann, E. Quintao, M. Passarelli, E. Nakandakare (Brazil) I. Khurana, A. Kaspi, M. Ziemann, T. Block, T. Connor, B. Spolding, A. Cooper, P. Zimmet, A. El-Osta, K. Walder (Australia) 284 1121 J. Dienova, K. Frimmel, L. Okruhlicova (Slovakia) J. Visek, A. Ticha, L. Sobotka, V. Blaha (Czech Republic) 283 ENDOTOXIN AND OMEGA-3 FATTY ACIDS EFFECTS ON ENDOTHELIAL OCCLUDIN EXPRESSION IN RAT HEART ANTIPLATELET EFFECT OF THE MAIN TRITERPENOIDS OF AN OLIVE LEAF EXTRACT1128 M. Tsoumani, V. Kontogianni, T. Kellici, T. Mavromoustakos, I. Gerothanassis, A. Tzakos, A. Tselepis (Greece) C. Parolini, F. Dellera, G.S. Ganzetti, S. Manzini, M. Busnelli, M.S. Ramsvik, B. Bjorndal, I. Bruheim, R.K. Berge, G. Chiesa (Italy) 289 INVESTIGATION OF CHIOS MASTIC GUM EFFECT ON METABOLIC PROFILE IN STREPTOZOTOCIN-INDUCED DIABETIC MICE 1119 A. Tzani, I. Georgiadis, L.M. Korou, P. Konstantopoulos, G. Agrogiannis, I. Vlachos, I. Doulamis, N. Katsilambros, D. Perrea (Greece) 290 ANTI-HYPERLIPIDEMIC POTENTIAL OF EMBLICA OFFICINALIS IN HIGH FAT FED RATS: UP-REGULATION OF PPARS 1120 B. Variya, S. Patel, A. Bakrania (India) 168 169 Poster Walks – tuesday Board # Board # Genetics, Nutrition, Biomarkers: Biomarkers 309 299 URINARY LIVER-TYPE FATTY ACID-BINDING PROTEIN IS ASSOCIATED WITH AORTIC STIFFNESS IN MALE CORONARY ARTERY DISEASE PATIENTS 300 IMPACT OF ALKALINE PHOSPHATASE ON IN-HOSPITAL MORTALITY AND 1-YEAR CLINICAL OUTCOME IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERWENT PRIMARY PERCUTANEOUS CORONARY INTERVENTION 310 THE GENERATION OF MALONDIALDEHYDE-POSITIVE MICROVESICLES 311 1130 LEUKOARAIOSIS IS UNRELATED TO CAROTID STENOSIS OR RISK FACTORS FOR ATHEROSCLEROSIS 1131 312 VARIABILITY AND TEMPORAL TREND OF VICORDER-ESTIMATED PULSE WAVE VELOCITY 313 314 EVALUATION OF OXIDATIVE STRESS INDEX AND ITS CORRELATION WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS, INFLAMMATION AND CAROTID INTIMA MEDIA THICKNESS IN DIABETES AND HEALTHY SUBJECTS 1134 PLASMA ARGININE/ADMA RATIO IS A SENSITIVE RISK MARKER FOR ATHEROSCLEROSIS: SHIMANE CoHRE STUDY 306 316 THE ALANINE AMINOTRANSFERASE/ ASPARTATE AMINOTRANSFERASE RATIO PREDICTS FUTURE CARDIOVASCULAR EVENTS IN PATIENTS WITH ESTABLISHED CORONARY ARTERY DISEASE AND HOMA INSULIN RESISTANCE1136 A. Vonbank, C. Saely, P. Rein, D. Zanolin, A. Leiherer, H. Drexel (Austria) 307 IMPACT OF AGE ON THE CARDIOVASCULAR EVENT RISK CONFERRED BY HbA1c IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE ProBNP STRONGLY PREDICTS FUTURE MACROVASCULAR EVENTS IN ANGIOGRAPHIED CORONARY PATIENTS WITH AS WELL AS IN THOSE WITHOUT TYPE 2 DIABETES 317 1137 1143 STATUS OF NOVEL CARDIOVASCULAR RISK FACTOR AND CARDIOVASCULAR DISEASE RISK IN AN URBAN DELHI POPULATION-A PILOT STUDY 1144 THE ATHEROGENIC PROFILE – PREDOMINANT LIPOPROTEIN PROFILE IN CARDIOVASCULAR DISEASE 1145 IMPACT OF NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN AND NEUTROPHIL COUNTS IN THE LUDWIGSHAFEN RISK AND CARDIOVASCULART HEALTH STUDY 1146 INCREASED LEVELS OF YKL-40 ARE ASSOCIATED WITH ALL-CAUSE MORTALITY IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE 1147 C.T. Herz, M.L. Tscharre, C. Höbaus, G. Pesau, F. Obendorf, R. Koppensteiner, G.H. Schernthaner (Austria) 318 1138 BRANCHED-CHAIN AMINO ACID PROFILES INDICATE CARDIO METABOLIC RISK INDEPENDENT OF BODY MASS INDEX R. Woitas, H. Scharnagl, M.E. Kleber, G.E. Delgado, T.B. Grammer, M. Pichler, B.K. Krämer, W. März, T. Stojakovic (Austria) A. Vonbank, C. Saely, D. Zanolin, P. Rein, A. Leiherer, H. Drexel (Austria) 308 1142 S. Prof. Dr. Oravec, K. Dr. Gruber, A. Prof. Dr. Dukat, P. Ass. Prof. Gavornik, L. Ass. Prof. Gaspar, E. Dr. Dostal (Slovakia) 1135 S. Yano, Y. Notsu, A. Nagai, T. Nabika (Japan) NITRIC OXIDE-RELATED CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH MAJOR DEPRESSION V. Sharma, R. Shahrawat (India) 315 R. Dalan, H. Liew, L.L. Goh, X. Gao, D.E. Chew, B.O. Boehm, M.K.S. Leow (Singapore) 305 1141 S. Zelzer, A. Meinitzer, D. Enko, G. Almer, R. Prassl, H. Mangge (Austria) 1133 A.K. Mistri, P. Connell, T. Robinson (United Kingdom) 304 THE INVERSE ASSOCIATION BETWEEN PLASMA ENDOGLIN LEVELS AND THE SEVERITY OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH STABLE CAD A. Meinitzer, S. Zelzer, H. Mangge, G. Almer, R. Prassl, O. AmouzadehGhadikolai, C. Robier, A. Baranyi (Austria) 1132 B. Muinjonov, E. Giyazitdinova (Uzbekistan) 303 1140 E. Saita, K. Miura, N. Suzuki, K. Miyata, N. Ikemura, R. Ohmori, Y. Ikegami, Y. Kishimoto, K. Kondo, Y. Momiyama (Japan) F. Puhm, T. Afonyushkin, C. Binder (Austria) 302 SIMPLE MORTALITY PROGNOSTIC RISK CALCULATOR FOR PATIENTS WITH ACUTE CORONARY SYNDROME N. Zagidullin, E. Travnikova, B. Zagidullin, R. Zulkarneev, S. Zagidullin (Russia) P.C. Oh, K. Woong Chol, M. Jeonggeun, S. Jon, P. Hyun Woo, J. Ho-Jun, K. Tae-Hoon, P. Sang-Don, K. Sung Woo, S. Soon Yong, L. Kyounghoon, H. Seung Hwan, A. Taehoon, S. Eak Kyun (Republic of Korea) 301 1139 F. Byazrova, V. Lopukhova, V. Buza, K. Zykov, Y. Karpov (Russia) 1129 K. Paapstel, M. Zilmer, J. Eha, K. Tootsi, A. Piir, J. Kals (Estonia) THE LEVEL OF EOSINOPHIL CATIONIC PROTEIN IS CORRELATE WITH SEVERITY OF CORONARY ATEROSCLEROSIS RELATIONSHIP OF INFLAMMATORY BIOMARKERS, PTX3 WITH SEVERITY OF PERIPHERAL ARTERIAL DISEASE 1148 K. Igari (Japan) P. Rein, C. Saely, A. Vonbank, D. Zanolin, A. Leiherer, H. Drexel (Austria) 170 171 Poster Walks – tuesday Board # 319 GALECTIN 3 AND THE REMODELING OF ARTERIAL WALL IN PATIENTS WITH METABOLIC SYNDROME Board # 329 1149 V. Ionin, D. Brovin, E. Bazhenova, T. Karonova, E. Polyakova, O. Belyaeva, E. Baranova, E. Shlyachto (Russia) 320 RELATION OF PLASMA COPEPTIN LEVELS AND WAIST CIRCUMFERENCE IN NON-DİABETIC ACUTE ST-SEGMENT ELEVATION MYOCARDİAL INFARCTION PATIENTS 321 1150 322 AORTIC VALVE STENOSIS IN ASSOCIATION WITH INFLAMMATORY PROCESS AND BIOCHEMICAL MARKERS. 331 ASSOCIATIONS OF LIPOCALIN 2 WITH MARKERS OF INFLAMMATION AND OXIDANT STATUS IN OBESE NON-DIABETIC PATIENTS 332 FIRST TRIMESTER SERUM CONCENTRATIONS OF AFAMIN ARE ASSOCIATED WITH THE DEVELOPMENT OF PREECLAMPSIA AND GESTATIONAL DIABETES MELLITUS IN PREGNANT WOMEN 1152 333 1153 IS RED BLOOD CELL GLUTATHIONE A BETTER MARKER FOR CORONARY ARTERY DISEASE THAN PLASMA GLUTATHIONE? 1154 CHANGES BRAIN NATRIURETIC PEPTIDE (BNP) LEVELS IMPROVE RISK PREDICTION OF SHORT-TERM MORTALITY FOLLOWING ACUTE MYOCARDIAL INFARCTION COMPARED TO GRACE SCORE: A BRASILIA HEART STUDY SUBANALYSIS 1155 334 335 1156 GENETIC DETERMINANTS CONTROLLING LIPID DEPOSITS IN DIFFERENT WILD TYPE STRAINS OF ZEBRAFISH (DANIO RERIO)1157 CELL-DERIVED MICROPARTICLES AS MARKERS OF ENDOTHELIAL FUNCTION, INFLAMMATION AND COAGULATION IN PATIENTS WITH SLEEP APNEA-HYPOPNEA SYNDROME: A SYSTEMATIC REVIEW BLOOD PRESSURE FLUCTUATIONS AS A LEADING LINK IN THE DEVELOPMENT OF COMPLICATIONS OF ATHEROSCLEROSIS 1163 ACC/AHA GUIDELINES SUPERIOR TO ESC/EAS GUIDELINES FOR PRIMARY PREVENTION WITH STATINS: THE COPENHAGEN GENERAL POPULATION STUDY1164 PREDICTING THE IMPACT OF THE ORIGINAL AND GENERIC ROSUVASTATIN ON DIRECT MEDICAL COSTS FOR SECONDARY PREVENTION IN PATIENTS WITH CHRONIC ISCHEMIC HEART DISEASE 1165 A. Merezhanova, E. Tarlovskaya, B. Nechaeva, A. Semenkin, S. Malchikova (Russia) 336 K. Vishnolia, K. Tarhbalouti, P. Ciba, C. Kruse, Z. Aherrahrou, J. Erdmann (Germany) 328 1162 M.B. Mortensen, B.G. Nordestgaard, S. Afzal, E. Falk (Denmark) L.S. Carvalho, L.A. Bogniotti, O.L. Almeida, J.C. Quinaglia e Silva, L. Trindade, G. Oliveira, A. Sposito (Brazil) 327 BIOMARKER DISCOVERY BY PLASMA PROTEOMICS IN FAMILIAL LMNA DILATED CARDIOMYOPATHY Genetics, Nutrition, Biomarkers: Guidelines and Miscellaneous A. Lima, R. Ferin, E. Santos, A. Fontes, S. Ferreira, C. Almeida, D. Martins, J. Baptista, M.L. Pavão (Portugal) 326 1161 A. Kebryakov, P. Bondarenko, M. Ermina, M. Ivanov, N. Koplyarova, A. Yadernaya, A. Mishchenko (Russia) A. Tramontana, B. Dieplinger, G. Stangl, E. Hafner, H. Dieplinger (Austria) 325 CAROTID ATHEROSCLEROSIS IN A VERY ELDERLY POPULATION: ROLE OF AGEING AND OTHER CARDIOVASCULAR RISK FACTORS I. Izquierdo, D. De Gonzalo-Calvo, V. Llorente-Cortes, I. Rosa, R. Brugada, C. Oscar, A. Perez-Serra, J. Broncano, A. Luna, J. Vazquez-Alfageme, J.R. Gonzalez-Juanatey, A. Mangas, A. Garcia, R. Toro (Spain) P. Fülöp, H. Lőrincz, S. Somodi, M. Harangi, I. Seres, G. Paragh (Hungary) 324 1160 F. Spannella, F. Giulietti, G. Cocci, P. Giordano, M. Ricci, E. Espinosa, R. Sarzani (Italy) J. Lūriņš, A. Visocka, V. Mackēvičs, P. Tretjakovs (Latvia) 323 THE NUMBER OF REQUESTS FOR HIGH SENSITIVE TROPONIN I MEASUREMENT AND THE NUMBER OF PATIENTS DIAGNOSED WITH ACUTE MYOCARDIAL INFARCTION L. Majnaric, M. Mikic, S. Bekic, S. Guljas (Croatia) CORRELATION OF PIGMENT EPITHELIUM-DERIVED FACTOR WITH OXIDATIVE AND INFLAMMATORY MARKERS IN OBESE, NON-DIABETIC PATIENTS1151 I. Juhász, I. Seres, A. Szentpéteri, E.V. Varga, S. Somodi, P. Fülöp, H. Lőrincz, G. Paragh (Hungary) 1159 J. Bogdanska, D. Labudovic, S. Alabakovska, S. Cekovska, K. Tosheska Trajkovska, S. Jovanova (FYR Macedonia) 330 K. Cosansu, A. Turer Cabbar, H.A. Cakmak (Turkey) ANTIOXIDANT ENZYMES IN PATIENTS WITH ATHEROSCLEROSIS APPLICATION OF A MULTILEVEL HIERARCHICAL MODEL TO CORRELATE TOTAL CHOLESTEROL IN EIGHT DIFFERENT SETTINGS 1166 A. Pereira, F. Guarnieri, A.P.Q. Mello, R. Santos Filho, T.L.R. Martinez (Brazil) 337 1158 PROPOSAL OF A NEW APPROACH TO ACCESS CHOLESTEROL RANGES ACCORDING TO DIFFERENT CONDITIONS 1167 A. Pereira, F. Guarnieri, A.P.Q. Mello, R. Santos Filho, T.L.R. Martinez (Brazil) A.J. Vallejo-Vaz, R. Muñoz-Hernández, J. Villar, P. Stiefel (United Kingdom) 172 173 Poster Walks – tuesday Board # 338 PREDICTING FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS’ QUALITY OF LIFE AND SELF-ASSESSED HEALTH: ILLNESS BELIEFS, BELIEFS ABOUT MEDICATION, AND HEALTH LITERACY Abstract not Registered 1168 400 M. Hagger, J. Pang, G.F. Watts (Australia) 339 METABOLIC DISTURBANCES AND RISK OF CANCER IN THE 25 YEARS FOLLOW-UP OF THE "VENTIMIGLIA HEART STUDY" EPIDEMIOLOGICAL PROJECT.1169 ESTRADIOL TREATMENTS CHANGE THE LIPID PROFILE IN NATURALLY MENOPAUSAL RATS FROM DIFFERENT AGE GROUPS: A THERAPEUTIC POTENTIAL DRUG FOR ATHEROSCLEROSIS 401 HYPONATREMIA : A RISK FACTOR OF OVERT HEPATIC ENCEPHALOPATHY 402 1170 EFFECTS OF OSTEOPATHIC MANIPULATIVE TREATMENT ON VASCULAR AND AUTONOMIC FUNCTIONS IN HEART PATIENTS: A RANDOMIZED, CLINICAL TRIAL 1171 F. Amatuzzi, A. Guervazoni, V. Marães, K. Bousquet, F. Stauffer, M.A. Catai, G. Chiappa, S. Thomaz, C. Nakata, R. Jácomo, M. Lucena, G. Cipriano Jr. (Brazil) S. Khedher, A. Maoui, K. Bouzid, S. Lahiani, A. Bartkiz, M. Salem, J. Abdelmoula (Tunisia) 342 403 HYPONATREMIA, A PREDICTING FACTOR OF MORTALITY IN CIRRHOTIC PATIENT1172 K. Bouzid, S. Khedher, A. Maoui, S. Lahiani, A. Bartkiz, M. Salem, J. Abdelmoula (Tunisia) 343 ANDROGEN-DEPRIVATION THERAPY-INDUCED ATHEROSCLEROSIS IN PROSTATE CANCER: DIFFERENCES BETWEEN GNRH-AGONIST AND ANTAGONIST1173 RELIABILITY ASSESSMENT OF DETERMINATION OF PROCALCITONIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS : ABOUT TWO CASES A. Bartkiz, K. Bouzid, S. Ghezaiel, S. Lahiani, S. Hammami, E. Talbi, A. Zannouri, M. Omrane, S. Barbouche, J. Abdelmoula (Tunisia) 1176 APPLANATION TONOMETRY PROPOSE DIFFERENT PHYSIOLOGIC MECHANISMS IN CHAGASIC VERSUS ISCHEMIC HEART FAILURE 1177 1178 A. Lima, J. Vilela-Martin, L. Giollo, A.P. Silva, M.E. Otto, S. Marianne, V. Maldaner, G. Chiappa, G. Cipriano, F. Amatuzzi, G. Cipriano Jr (Brazil) 404 W. Duivenvoorden, S. Hopmans, G. Werstuck, J. Pinthus (Canada) 344 RELATIONSHIP BETWEEN CAROTID INTIMA-MEDIA THICKNESS AND THE WEIGHT GAIN T. Alexescu, I. Cheta, M. Handru, V. Negrean, L. Ciumarnean, I. Para (Romania) P. Kumar, N. Baquer (India) 341 1175 Z. Aktop, E. Coskun (Turkey) D. Noto, A.B. Cefalù, C.M. Barbagallo, A. Giammanco, F. Fayer, O. Palesano, G.I. Altieri, R. Spina, V. Valenti, M. Pagano, G. Cavera, M.R. Averna (Italy) 340 WHAT WOULD YOU DO IF YOU WERE WITH AN EMBRYO-LIKE GIANT THROMBUS IN THE LEFT VENTRICLE: CASE REPORT PREVALENCE OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA AND IMPACT ON ACHIEVEMENT OF LIPID TARGETS DURING CARDIAC PREVENTION AND REHABILITATION PROGRAMMES IN ITALY: THE HEREDITY REGISTRY 1179 M. Ambrosetti, P. Faggiano, P.L. Temporelli, R. Griffo, R. Pedretti (Italy) 405 PEDIATRIC IMT ASSESSMENT 1180 E. Barabesi, O. Guardamagna, F. Abello (Italy) 1174 406 RISK FACTORS FOR DEVELOPING DRUG-RELATED PROBLEMS IN PATIENTS WITH CARDIOVASCULAR DISEASES ATTENDING GONDAR UNIVERSITY HOSPITAL, ETHIOPIA 1181 A. Bhagavathula, O. Abubeker, A. Elnour, A. Shehab (Ethiopia) 407 CLINICAL UTILITY OF DABIGATRAN IN UNITED ARAB EMIRATES. A PHARMACOVIGILANCE STUDY 1182 A. Shehab, A. Elnour, A. Bhagavathula, S. Al Nuaimi (United Arab Emirates) 408 A MUFA RICH-DIET MAY REDUCE LIVER FAT CONTENT IN TYPE 2 DIABETES PATIENTS THROUGH AN ENHANCED POSTPRANDIAL FAT OXIDATION 1183 L. Bozzetto, G. Costabile, G. Annuzzi, D. Luongo, D. Naviglio, V. Cicala, M. Giorgini, C. Piantadosi, E. Griffo, P. Cipriano, A. Giacco, A. Rivellese (Italy) 409 AN ASSOCIATION STUDY OF EARLY-LIFE ARSENIC EXPOSURE ON THE RISK OF HYPERTENSION, HYPERGLYCEMIA, AND HYPERLIPIDEMIA 1184 H.Y. Chiou, S.Y. Kuo, F.I. Hsieh (Taiwan) 174 175 Poster Walks – tuesday 410 NOVEL EFFECTS OF SARCOPENIC OSTEOARTHRITIS ON METABOLIC SYNDROME AND INSULIN RESISTANCE: THE NATIONAL SURVEY 421 1185 S.M. Chung, M.H. Hyun, H.S. Seo, D.J. Oh, C.G. Park, S.W. Rha, E.J. Kim, H.E. Lim, J.W. Kim, C.U. Choi, J.O. Na, S.K. Lee (Republic of Korea) 411 412 THE EXPRESSION OF MIR-125A-3P IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF PATIENTS WITH CORONARY HEART DISEASE 1186 H.L. Dai, X.L. Yin, J. Xiao, X.F. Guang (China) CARDIOVASCULAR DISEASE RISK ASSESSMENT: TRIGLYCERIDE/ HIGH-DENSITY LIPOPROTEIN VERSUS METABOLIC SYNDROME CRITERIARUNNING TITLE: CVD RISK ASSESSMENT: TG/HDL VERSUS METS ENDOTHELIAL VASCULAR MOTOR FUNCTION IN ARTERIAL HYPERTENSIVE PATIENTS1187 M. Gharipour, M. Sadeghi, P. Nezafati, N. Sarrafzadegan (Iran) ROSUVASTATIN COMPARED TO ATORVASTATIN ON LIPID PROFILE AND APOLIPOPROTEIN LEVELS IN DYSLIPIDEMIC PATIENTS WITH ELEVATED LIPOPROTEIN (a) 422 423 RESPONSE TO AN ORAL FAT LOAD WITH A NON DAIRY CHEESE CREAM CONTAINING FERMENTED SOYBEAN EXTRACT SOY COMPARED TO A DAIRY CHEESE IN HEALTHY SUBJECTS 424 1188 EFFECTS OF A NON DAIRY CHEESE CREAM CONTAINING FERMENTED SOYBEAN EXTRACT ON LIPID PROFILE AND LIPOPROTEINS IN DYSLIPIDEMIC PATIENTS 425 1189 EVALUATION OF LIPID-LOWERING THERAPYPREFACINGACUTE CORONARY SYNDROME AND FATSDEPENDING ON CARDIOVASCULARRISK GROUP OF PATIENTS WITH ATRIAL FIBRILLATION 1190 426 1191 RENOPREDICT: MULTIPLE BIOMARKER APPROACH TO IMPROVE THE PREDICTION OF MORTALITY IN DIALYSIS PATIENTS 427 1192 PROGRANULIN MAY BE A BIOMARKER OF PERIPHERAL ATHEROSCLEROTIC DISEASE1193 E. El Eter, H. Al Zamil, L. Al Dokhi, M. Al Omran (Egypt) 419 MATERNAL ENDOTHELIUM AND RISKS OF DEVELOPING CARDIOVASCULAR DISORDERS RELATIONSHIP BETWEEN THE LOCATION OF LESION AND THE ASSOCIATED ARRHYTHMIAS AND CONDUCTION ABNORMALITIES IN PATIENTS WITH MYOCARDIAL INFARCTION 428 ABNORMAL METABOLIC CONDITIONS ARE INDEPENDENT RISK FACTORS FOR INCREASED ARTERIAL STIFFNESS INDEPENDENT OF AGE AND BLOOD PRESSURE 1201 THE RATIO OF SKELETAL MUSCLE MASS TO VISCERAL FAT AREA IS A MAIN DETERMINANT LINKING CIRCULATING IRISIN TO METABOLIC PHENOTYPE 1202 1194 1203 RESPIRATORY FUNCTION OF LUNGS AT ISCHEMIC HEART DISEASE PATIENTS CONCOMITANT WITH TYPE 2 DIABETES MELLITUS 1204 S. Murtazaev, A. Mansurov, N. Sharapov, K. Khalikulov (Uzbekistan) 430 1195 PLATELET RELEASE REACTIONS ARE MODIFIED IN VITAMIN D DEFICIENCY L. Kasatkina, I. Trikash (Ukraine) 429 A. Fatima (Pakistan) 420 CLINICAL OUTCOMES OF MULTI-VESSEL CORONARY ARTERY SPASM ARE COMPARABLE TO SINGLE VESSEL SPASM ON RECOMMENDED OPTIMAL MEDICAL TREATMENTS: KOREA VASOSPASTIC ANGINA REGISTRY DATA ANALYSIS1200 Y.C. Hwang, P. Cheol-Young, Y. Byung-Soo (Republic of Korea) C. Drechsler, W. März, V. Krane, B. Kollerits, F. Kronenberg, C. Wanner (Germany) 418 1199 S.H. Han, H. Hyo Sang, O. Pyung Chun, K. Kwang Kwon (Republic of Korea) Y. Dorofeeva, E. Tarlovskaya, S. Malcnikova (Russia) 417 THE MOST COMMON CARDIOVASCULAR RISK FACTORS IN ADOLESCENTS SIGNIFICANT FOR DEVELOPMENT OF CARDIOVASCULAR DISEASES IN ADULTHOOD S.H. Han, O. Pyoung Chun, S. Dong Il, H. Sung Ho, A. Youngkeun, P. Keun Ho, K. Dong Soo, Y. Tae Hyun, C. Dong Ju, S. Jung Won, K. Hyuck Moon, L. Byoung Kwon, G. Hyeon Gheol, R. Seung Woon, J. Sang Ho, B. Sang Hong (Republic of Korea) G. Derosa, D. Romano, A. D'Angelo, P. Maffioli (Italy) 416 1198 G. Grujic Ilic (Serbia) G. Derosa, D. Romano, A. D'Angelo, P. Maffioli (Italy) 415 CARDIOVASCULAR RISK IN CHILDREN: THE CLINICAL RELEVANCE OF EARLY AND TIMELY STRATIFICATION AND TREATMENT 1197 I. Gomes, B. Cardoso, P. Loureiro, M. Bourbon, F. Pinto (Portugal) G. Derosa, D. Romano, A. D'Angelo, P. Maffioli (Italy) 414 1196 B. Gaye, P. Boutouyrie, G. Parati, M.C. Perier, F. Thomas, C. Guibout, B. Pannier, X. Jouent, J.P. Empana (France) N. Demikhova, O. Chernatskaya, Y. Smiianova, O. Smiianova, L. Vynnychenko (Ukraine) 413 ASSOCIATION OF IDEAL CARDIOVASCULAR HEALTH WITH SUBCLINICAL VASCULAR STRUCTURE FUNCTION AND ELASTICITY IN THE COMMUNITY. THE PARIS PROSPECTIVE STUDY 3 FREQUENCY OF STATIN DOWNTITRATION DURING OPEN LABEL EVOLOCUMAB TREATMENT IN THE OSLER-2 STUDIES 1205 M. Koren, Y. Ma, R. Somaratne, M. Bolognese (USA) U. Ganiev, S. Khaitov, M. Kenjaev (Uzbekistan) 176 177 Poster Walks – tuesday 431 HIGH LYMPHOCYTES AND LOW MEAN CORPUSCULAR VOLUME ARE ASSOCIATED WITH DIABETES, TRIGLYCERIDE-TO-HIGH-DENSITYLIPOPROTEIN RATIO AND METABOLIC SYNDROME, IN PATIENTS AT HIGH RISK OF CORONARY ARTERY DISEASE 442 432 NUMBER OF BLOOD PRESSURE MEASUREMENTS NEEDED TO ESTIMATE LONG TERM VISIT-TO-VISIT SYSTOLIC BLOOD PRESSURE VARIABILITY FOR PREDICTING 10-YEAR CARDIOVASCULAR RISK 443 433 444 PLASMA TRIMETHYLLYSINE, TRIMETHYLAMINE-N-OXIDE, CARNITINE AND INCIDENT MYOCARDIAL INFARCTION IN PATIENTS WITH STABLE ANGINA PECTORIS1208 K.H. Løland, H. Olset, G.F.T. Svingen, H. Schartum-Hansen, E.K. Pedersen, E. Strand, P.M. Ueland, A. Svardal, Ø. Bleie, J.E. Nordrehaug, O. Nygård (Norway) 434 435 445 IMPACT OF INSULIN RESISTANCE ON CARDIAC AND VASCULAR FUNCTION 1209 G. Manno, S. Novo, R. Russo, D. Buccheri, S. Dell'Oglio, P. Morreale, G. Vitale, G. Novo (Italy) Y.R. Sigurðardóttir, B.R. Stefánsdóttir, T. Aspelund, G. Þorgeirsson, V. Guðnason, L.B. Kristinsdóttir, K. Andersen (Iceland) 446 1210 NIGELLA SATIVA AND THYMOQUINONE REDUCE GENE AND PROTEIN EXPRESSION OF INTERLEUKIN-6 VIA NUCLEAR FACTOR KAPPA B PATHWAY 438 447 1211 OXIDATIVE-ANTIOXIDATIVE CHANGES OF LDL, CORONARY HEART DISEASE, SOME ATHEROSCLEROSIS RISK FACTORS AND 7-YEAR UNFAVORABLE LONG-TERM RESULTS IN MEN POPULATION OF NOVOSIBIRSK1212 N. Soltani, M. Fazali, F. Kharazmi, M. Kamran (Iran) ALCOHOL AND PREMATURE CARDIOVASCULAR MORTALITY IN BELARUS LEG MINUS ARM PULSE WAVE VELOCITY MEASURED WITH A NEW DEVICE CORRELATES WITH CAROTID FEMORAL PULSE WAVE VELOCITY LEG MINUS ARM PULSE WAVE VELOCITY MEASURED WITH A NEW DEVICE CORRELATES WITH CORONARY CALCIUM SCORE 1220 1221 448 1213 449 1214 THE LEADING RISK FACTORS FOR DEVELOPMENT OF MYOCARDIAL INFARCTION IN ELDERLY PATIENTS 1223 1224 I. Sukmanova, I. Zheltova (Russia) 450 GENDER-SPECIFIC RISK FACTORS OF MYOCARDIAL INFARCTION 1225 I. Sukmanova, I. Suspitsyna (Russia) 1215 451 1216 1222 K. Sirojiddin, D. Alimov, B. Mukhamedova, M. Kenjaev, R. Rakhimova (Uzbekistan) ISCHEMIC HEART DISEASE MORTALITY AND ALCOHOL CONSUMPTION IN THE FORMER SOVIET REPUBLICS: A COMPARATIVE ANALYSIS OF TRENDS S. Rico Martin, J.F. Sánchez Muñoz-Torrero, J.F. Calderón García, J.M. De Nicolás Jiménez (Spain) 441 EFFECTS OF HIGH-DOSE ATORVASTATIN PRETREATMENT ON MYOCARDIAL STUNNING IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION EFFECT OF LOX1 RECEPTOR GENE EXPRESSION BY ORAl MgSO4 ADMINISTRATION TO CONTROL ATHEROSCLEROSIS IN STZ-INDUCED DIABETIC RAT Y. Razvodovsky (Belarus) 440 ASSESSMENT OF THE RISK OF PERIPHERAL ARTERIAL DISEASE IN PATIENTS WITH CORONARY ARTERY DISEASE Y. Ragino, Y. Polonskaja, S. Malyutina, M. Voevoda (Russia) Y. Razvodovsky (Belarus) 439 1219 K. Sirojiddin, A. Alavi, M. Kenjaev (Uzbekistan) F. Mohtar, H. Nawawi, T. Rahman, G.R.A. Froemming (Malaysia) 437 CAROTID INTIMAL-MEDIAL THICKNESS ,PREVALENCE OF DOCUMENTED CORONARY AND CEREBRAL VASCULAR ATHEROSCLEROTIC DISEASES IN PATIENTS WITH ABDOMINAL AORTIC ANEURISM AND AORTO-ILIAC OCCLUSIVE DISEASE ENDOTHELIAL FUNCTION ASSESSED BY PERIPHERAL ARTERIAL TONOMETRY IS NOT RELATED TO CARDIOVASCULAR RISK SCORE IN HEALTHY SUBJECTS ASSOCIATION OF CAROTID ATHEROSCLEROSIS WITH CORONARY ARTERY DISEASE: A RETROSPECTIVE STUDY OF 589 PATIENTS 1218 N. Sharashidze, I. Botchorishvili, Z. Pagava (Georgia) D. Migliorino, A. Mignano, S. Evola, G. Novo, E. Corrado, S. Novo (Italy) 436 ASSOCIATION BETWEEN 677C>T POLYMORPHISM WITHIN METHYLENETETRAHYDROFOLATE REDUCTASE GENE AND POSTSTROKE HEMIPARESIS IN POLISH PEDIATRIC PATIENTS B. Sarecka-Hujar, I. Kopyta, I. Zak, E. Emich-Widera (Poland) 1207 H.M. Lim, Y.C. Chia, S.M. Ching (Malaysia) 1217 T. Ristic, V. Djordjevic, V. Cosic (Serbia) 1206 B. LI, I. Trakarnwijitr, H. Adams, J. Layland, J. Garlick, A. Wilson (Australia) THE ROLE OF TRACKING OF BCL-2 AND CASPASE-3 ACTIVITY IN PLAQUE EVOLUTION IN ISCHEMIC HEART DISEASE PATIENTS THE ROLE OF PSYCHOSOMATIC FACTORS AND HYPODYNAMIA IN THE DEVELOPMENT OF MYOCARDIAL INFARCTION IN MIDDLE AND ELDERLY WOMEN1226 I. Suspitsyna, I. Sukmanova (Russia) J.F. Sanchez Munoz-torrero, S. Rico Martin, J.M. De Nicolas Jimenez, J.F. Calderon Garcia (Spain) 178 179 452 EFFECT OF ALPHA-LIPOIC ACID SUPPLEMENTATION ON OXIDATIVE STRESS MARKERS AND ANTIOXIDATIVE DEFENSE IN PATIENTS WITH DIABETIC NEUROPATHY 1227 F. Sztanek, I. Seres, H. Lőrincz, A. Molnár, G. Paragh (Hungary) 453 COMPARISON OF EFFECTIVENESS OF DIFFERENT ANTIPLATELET DOSES OF ASPIRIN IN PATIENTS WITH ACUTE CORONARY SYNDROME 1228 T.S. Tan Kurklu (Turkey) 454 PREVALENCE OF FAMILIAL HYPERCHOLESTEROLAEMIA IN PATIENTS WITH ISCHEMIC STROKE OR HIGH-RISK TIA 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria 1229 T. Toell, L. Mayer, K. Willeit, M. Knoflach, S. Kiechl, J. Willeit (Austria) 455 Integrative Analysis of Gene Expression Network for Atherosclerosis-related disease and Nutraceuticals Supplements1230 L. Torres, A. Obregon-Gonzalez, V. Padilla-Mata (Mexico) 456 EVALUATING MONITORED LEVELS OF TOTAL CHOLESTEROL AND APPLICATION OF LIPID-LOWERING THERAPY IN PATIENTS WITH DIABETES MELLITUS AND ISCHEMIC HEART DISEASE IN AN ACTUALLY AMBULATORY PRACTICE1231 F. Valikulova, I. Fomin, A. Vaysberg, E. Gurvich, M. Boldina (Russia) s r o th u A f Index o 180 www.eas2016.kenes.com INDEX A Aguilar-Salinas, C. 945 Ali, M.Z. 820 Abajo, M. 774 Aherrahrou, Z. 1 157 Alimov, D. 1 222 Abd Alla, J. 1 024 Ahmad, R. Alkaaby, W. 666 Abdelmoula, J. 858, 859, 867, 909, 1 091, 1 111, 1 171, 1 172, 1 174 485, 486, 487 Allanov, R. 752 Ahmed, O. 89, 1 027 Allaoui, F. 691 Ahmed, S. 529 Allen, R. 268 Aigner, E. 662 Almaghraby, A. 587, 790 Abdijalilova, S. 567, 570, 571 Aikawa, E. 42, 93 Almagro, F. 358, 921, 975 Abdul Rahman, T. 923 Aikawa, M. 42 Almeida, C. 1 155 Abdul Razak, S. 441, 716, 923, 965, 966 Aittokallio, T. 378 Almeida, O.L. 1 156 Ajendra, J. 377 972 Akhvlediani, M. 844 Almendros Afonso, T.K. Abdulgamidov, M. 793 Akin, I. 274 Almer, G. Abe, K. 583 Akita, N. 375 894, 1 142, 1 143 Abedpour Dehkordi, A. 721 Akiyama, T. 855 almusawi, A. 887, 891, 896 987, 1 058, 1 180 1 038 887, 891, 896 Abello, F. Akrami, A. alnafakh, H. Akramova, D. 608 Alomar, S.Y. 849 Aktan, M. 984 866 Akther, F. 508 Alonso Moreno, F.J. Aktop, Z. 1 175 Alonso, R. 945 akturk, F. 826 Alshehry, Z. 314 Akyol, T. 984 Alt, K. 223 Al Dokhi, L. 1 193 Altamura, S. 102 al mohy, Y. 798 Altieri, G.I. 954, 1 169 Al Nuaimi, S. 1 182 Altieri, P. 553 Al Omran, M. 1 193 Altunkeser, B. 984 Al Zamil, H. 1 193 Alvarez de Sotomayor, M. 381, 1 125 Abeysekera, A. 933 Abifadel, M. 946 Abubeker, O. 1 181 Achenbach, S. 377, 1 069 Achmad, C. 576 Adam, S. 426 Adamcova, K. 889, 892 Adamek, V. 724 Adamkova, V. 724, 939, 1 068 Adamova, I. 687 Al-Banna, R. 568 Alvarez-León, E. 356 Adams, H. 723, 1 206 Alabakovska, S. 678, 1 159 Alvarez-Llamas, G. 129 Adamski, J. 290 Alaeddin, A. 849 Alves, A.C. Adorni, M.P. 697, 715 Alain, V.D. 283 Adrian, G. 801 Alavi, A. 1 221 943, 945, 955, 985, 1 060 Adyrkhaev, Z. 793, 906, 911 Albareda, M. 1 012 Alves, R. 799 Adzhemian, N. 606 Albasri, A. Amadio, P. 222 Adzhiev, R. 685 891, 896, 887 Amarchand, R. 767 Alberico L, C. 898 Amatuzzi, F. 1 177, 1 178 Alcantara, K. 522 Ambadapadi, S. 107, 1 028 AldamizEchevarria, G. 129 Ambrosetti, M. 1 179 Amigó, N. 393, 434 Afanasieva, M. 679 Afanasieva, O. 551, 679, 685, 686, 687 Afonyushkin, T. 1 131 Alegret, M. 508, 1 123 Amin, R. 126, 655 Afzal, S. 427, 1 164 Aleksandrova, K. 412 Ammirati, E. 616 Ager, M. 942 Alekseeva, O. 1 042 Ammori, B.J. 426 Aghi, A. 1 029 Alexandra, S. 830 Amores-Arriaga, B. 505 AGOP, M. 575 Alexescu, T. 82 AmouzadehGhadikolai, O. 1 142 Agrawal, D. 913, 992, 1 176 Agrogiannis, G. 1 119 Alexiev, A. 914, 917 An, G.J. 512 Aguiar, P. 360 Alfaro, F. 428 An, K.J. 739 Aguilar Salinas, C. 959 Ali, A.M. 485 Ananthaseshan, S. 800 183 INDEX 184 Anastassopoulou, J. 813 Anđelković, K. 122 Andersen, K. 450, 491, 1 058 Averna, M. 11, 121, 232, 388, 954 Baptista, J. 1 155 Bayly, G. 969, 1 051 Berbée, J. 90, 556 Baquer, N. 847, 1 170 Bays, H. 389 Berdiqulov, J. Arnesen, H. 1 102 572, 1 018 Averna, M.R. 1 169 Barabesi, E. 987, 1 180 Bazhenova, E. Berestetskaya, Y. 687 477 Ayami, S. 63 Baragetti, A. Berg Schmidt, E. 654 Arnoldi, A. 386 Ayaori, M. Bchir, N. 867 Berg-Schmidt, E. 1 102 1 043 Arola, J. 915 693, 700, 1 049 238, 616, 898, 1 063 740, 890, 1 149 1 220 Arnhard, K. Andersen, O.M. 332 Andor, M. Baragetti, I. 898 Bea-Sanz, A.M. 115 707 Aronov, D. 982, 998 777 995 Andrea, B. Ayca, B. Berg, G. Baral, B. 659 Bea, A. 765 475 Arpad Faludi, A. 972 1 061 1 055 Andrea, T. Azevedo, O. Berge, K.E. Barale, C. 276 Bea, A.M. 971 654 Arrondo, J.L.R. 637 1 061 363, 1 118 Andreasen, A. Azevedo, P. Berge, R.K. Baranova, E. Beacham, L. 61 Arroyo, D. 774 955, 985 244 654 Azevedo, S. Bergheanu, S. Andreasen, J.J. 740, 890, 1 149 Becher, B. 127 446 Arsenault, B. 119, 387 843 Barany, P. 47 307 Andréasson, A.C. Azinheira, J. Bergthaler, A. Becher, T. 274 830 Arsiwala, T. 127 Baranyi, A. 1 142 890 Andreev, V. B Berkovich, O. Beck, W. 641 356, 528 Artemieva, N. 687 861 Barbagallo, C.M. 954, 1 169 563 Angeles-Martínez, J. Babadjanov, B. Berliner, S. 956 850 Babets, A. 577 Barbarash, O. Angelin, B. 336 Artemova, N. 613 Baccar, H. Beer, J.H. 127 Arutyunova, M. 860 1 122 494 697 Barbeiro, D. Bernabeu, C. Angelino, D. 858, 859, 867, 1 091 520, 573, 1 086 Bermudez Pulgarin, B. 1 125 Artemova, A. BednarskaMakaruk, M. Begum, H. 223 794 Arzt, C. 448 Barbieri, S. 222 565, 1 015 Angelopoulou, S. 463 Bernatova, I. Behl-Gilhotra, R. 362 855 Asai, A. 886 1 174 81, 106, 547 Ann, T. Barbouche, S. Bernelot Moens, S. Asaji, M. 63 Bardova, K. 889, 892 1 096 947 1 102 Bekers, O. Ansheles, A.A. Badimon, L. Bernelot Moens, S.J. 627 1 183 1 115 446 Annuzzi, G. Bachti, E. Behrendt, M. Asako, K. 457 Barichello, M. 725 425 617, 618 Bernfur, K. 408 694 Ascaso, J. 975 BaenaFustegueras, J.A. Bekiari, E. Ansmidte, O. Barinova, V. 1 075 Bekic, S. 1 160 Bernhagen, J. 291 Anto Michel, N. 224, 470 Ascaso, J.F. 358, 766, 921 Baena, M. 508, 1 123 Barkas, F. Bekkering, S. 106, 270, 556 Bernhard, D. 477 Antonini-Canterin, F. 599 Ascerov, N. 793 Baeten, D. 547 432, 753, 928, 977, 978, 1 003 Belagha, J. 859 Bernini, F. 692, 697 204 Berrougui, H. 110 Antonopoulou, S. 1 115 Antonov, K. 917 Antonucci, A. 725 Antunes, H. 1 061 Antunes, M. 993 Anwar, A. 658 Aoyama, N. 747 Ass. Prof. Gavornik, 1 145 P. Aprami, T. 576 Asselbergs, F.W. 240 Aquila, G. 1 022 Asset, G. 246 Aquilera, J. 434 Assinger, A. 448 Aragon, V. 1 109 Assmann, G. 66 Aragona, C.O. 496, 506, 588, 675, 1 050 Astanina, K. 492 Astrakov, S. 644, 964 Astrakova, K. 644, 964 Atanasovska, B. 113 Atangwho, I. 1 124 Atkin-Smith, G. 489 Attia, N. 638 Auer, S. 662 Aurelian, S.M. 609, 792 Auwerx, J. 127 Auzky, O. 515, 871 Avdeeva, I. 590 Averkova, A. 785 Arakelyan, A. 1 047 Araz, T. 1 083 Arca, M. 121 Arefieva, T. 551, 679 Ares Jr., M. 269 Argimón, J. 944 Argyrou, C. 1 117 Arisaka, O. 390 Ariza, M.J. 428 Armitage, J.M. 51 Arnaboldi, L. Baccara-Dinet, M.T. Ashavaid, T. 1 062 Baetta, R. 472 Barlow, C. 314, 449 Belevich, I. Ashford, M. 289 Bagheri, B. 566 Barnes, E. 314 Belhadj Hassen, H. 858 Berta, E. 612 Ashor, A. 1 114 Bahlous, A. 1 111 Barrett, P.H.R. 394, 471 Bell, D. 355 Bertaccini, D. 283 869 Bertagnin, E. 671, 749 Aspelund, T. 1 220 Baila-Rueda, L. 115, 765, 971 Barros, P. 985 Belovol, A. Ass. Prof. Gaspar, L. 1 145 Bairaktari, E. 709 Bartelt, A. 48 Beltowski, J. 468 Berteotti, M. 616 Bakker, L. 90 Barter, P. 119 Beltrami-Moreira, M. 93 Berti, A. 616 Bertinaria, M. 1 017 Belyaeva, O. 1 149 Bertocco, S. 725, 1 029 Ben Abdallah, N. 858, 859, 867, 909, 1 111 Bertolini, S. 121 Bertsch, T. 858, 859, 867, 1 091 368, 438, 1 098 Beshay, M. 797 Benaiges, D. 1 012 Besseling, J. 99, 359, 974 Benczur, B. 414 Betriu, À. 774 Benghozi, R. 714 Bezrodnyi, V. 811 Benítez, S. 876 Bhagavathula, A. 1 181, 1 182 Benito-Vicente, A. 637, 985, 1 056 Bhasin, P. 780 Bianco, A. 1 097 569 Bianconi, V. 865 Biazzi, C. 898 123, 429, 1 080 Bielicki, J. 641 Biemann, R. 412 Biessen, E. 704 Biessen, E.A.L. 269 Bigolin, P. 725 Bakker, S.J.L. 1 100 Barter, P.J. 342 Bakrania, A. 1 120 Bartkiz, A. Balakhonova, T. 551, 582, 679 867, 909, 1 091, 1 111, 1 171, 1 172, 1 174 Balandina, Y. 776 Balashenka, N. 581 Bartolini-Gritti, B. 307 Balatskaya, N. 606 Baruah, P. 40, 459 Balder, W. 413 Bassani Borges, J. 972 Bassendine, M. 369 Balla, J. 467 Ballantyne, C. 61 Bast, A. 1 096 Baltatzi, M. 736 Battista, S. 692 Ben Ahmed, H. Balu, N. 248 Baudin, B. 638 Bałys, M. 1 071, 1 084 Bauer, R. 622 Balzarotti, G. 431 Baumann, S. 274 Benjathummarak, S. Ban, Z. 285 Baumgartner, J. 418 Benn, M. Banach, M. 259, 672 Baumgartner, S. 1 096, 1 104 Bañares, V. 945 956 Banchs, H.L. 553 BautembachMinkowska, J. Bao, W. 119 Bawelski, M. 585 Benoist, J.F. 691 Bento, D. 1 061 Benvegnù, L. 1 029 185 INDEX Bilgic, E. 294 Billon-Crossouard, S. 648 Boutouyrie, P. 1 196 Buchal, R. 517 Calabrò, P. 924, 925 Castagna, A. 626, 656 Bouziana, S. 794, 1 088 Buchmann, N. 935, 989 1 216, 1 215 Castelnuovo, S. 963 Bouzid, K. 858, 859, 867, 909, 1 091, 1 111, 1 171, 1 172, 1 174 Buda, V. 1 043 Calderón García, J.F. Binder, C. 1 096, 1 131 Bonde, Y. 376 Binder, C.J. 36, 39, 307 Boni, M. 849, 865 Bueno, M. 944 Caliceti, C. 1 022 Castiglioni, L. 1 039 Buerger, C. 305 Caligiuri, G. 451, 474 Castillo Bernal, F.J. Biolo, M. 1 029 Bono, E. 1 034 Bugrova, O. 613, 848 Calosing, C. 118 835, 836, 837 BirnerGruenberger, R. 440 Bonora, E. 312 Boodhoo, D. 536 Bouzourene, K. 1 019 Bujo, H. 330 Camejo, G. 47 Bowden, K. 455 Bülow Eschen, R. 654 Camera, M. Castro Jiménez, M.C. 835, 836, 837 Boya, P. 346 Bundalo, M. 373 1 033, 1 034, 1 039 Birringer, M. 383 Boon, M. 90, 111, 556 Bispo, K. 1 122 Boonen, H. 513 Catai, M.A. 1 177 Boyd, M. 498 Bürger, C. 128 CAN, L.H. 951 Catanozi, S. Bittar, R. 365 Boosani, C. 82 698, 1 122 Boydens, C. 856 Burger, F. 407 Catapano, A. biyik, I. 826 Boot, C. 988 Boyle, J.R. 743 Burko, N. 603, 1 044 Boytsov, S. 629, 640, 663 Burlachuk, V. 750 Burnett, J. 355 Bozorboev, M. 744 16, 19, 24, 26, 30, 132, 250, 252, 256, 258, 315, 321, 324, 472 Björkbacka, H. 290 Borén, J. Bjorndal, B. 1 118 241, 10, 43, 647 Blackhurst, D. 710 Borges Jr, N. 799 Blaha, M. 1 026 Borggrefe, M. 274 Burnett, J.R. 471 976, 1 026, 1 112 Borghi, C. 380, 391, 671, 749 Bozzetto, L. 1 183 Catapano, A.L. Burokiene, N. Bozzolo, E. 616 682 Brænne, I. 240 Borowiec, M. 828 Brambilla, M. 222, 238, 347, 392, 431, 458, 554, 616, 1 063 358, 384, 944 Bornstein, S.R. Blangero, J. 449 Borrallo, R.M. 938 Blauw, L. 113 Borst, J. Bleie, Ø. 1 208 Bliden, K.P. Block, T. Blaha, V. Blanco-Vaca, F. Bondarenko, P. Castelo-Branco, M. 592 CANET-SOULAS, E. 292 Cannon, C.P. 463 Canton, G. 248 Cantor, R.M. 241 Canzano, P. 1 033, 1 034, 1 039 1 072 Cao, L.L. 94 Bursill, C. 704 Capelozzi, V. 1 122 Burtceva, E. 1 023 1 034, 1 039 Capisizu, A. 609, 792 Busacca, P. 803 Brambilla, S. 450 Capobianco, E. 825 Busnelli, M. Cattan-Lévy, L. 474 Brandon, J. 95 Cappellano, G. 351 Cattaneo, F. 450 305 956 1 017 Caussy, C. 625, 1 057 721 Brandt, A. Capra, V. Boshtam, M. 131, 372, 511, 639, 689, 1 118 1 102 Cavalca, V. 530 386 Bratseth, V. 863 Bosisio, R. 351 Caramelli, B. 417 Buszko, M. Brea, Á. 975, 766 407 Cavalot, F. 276 74, 322 113 Carbone, F. 1 113 Buurman, W. Breierova, E. 565, 1 015 Buza, I. 513 Cavera, G. 1 169 88 Buza, V. 782, 1 139 Cárdenas Vázquez, 945 A. cebe, H. 826 1 139 Cardoso-Saldaña, G. 528 Cecchettini, A. 825 Cardoso, B. 1 198 Cecconi, D. 626, 656 Cedó, L. 384 Cefalù, A.B. 121, 954, 1 169 Čejková, S. 535 Cekovska, S. 1 159 Cena, C. 1 017 Cenarro, A. 115, 202, 765, 971 Blom, D. 976 Bossano Prescott, E. Bobabekov, A. 851, 861 Bossone, E. Bobbert, T. 989 Bosusco, A. 987, 1 105 Bridges, I. 462, 1 009 Byazrova, F. Bobronnikova, L. 869 Bot, I. 307 Brisson, D. 660, 1 053 Byazrova, S. 473, 853 Bocskei, R. 414 Botchorishvili, I. 781 Byoung Kwon, L. 1 200 Cardoso, G. 356 Bode, . 224 921 Brix, S. 285 1 202 Cardouat, G. 281 Bode, C. 306, 470 Botet-Montoya, J.P. Byung-Soo, Y. Broncano, J. 1 162 Bzduch, V. 1 052 Carerj, S. 599 Botha, S. 619 Broncel, M. 518, 828 C Caretta, N. 725 Botirova, L. 571 Brouwer, I. 56 Cabré, C. 434 Carey, A. 223 995 Carletti, R. 549 Carmeliet, P. 27, 140 Carnuta, M.G. 701, 1 082 Cermenati, G. 267 Caro Gomez, N. 614 Ceska, R. 962 Caro, N. 888, 904, 1 099, 1 109 Chabowski, A. 1 016 Chae, I.H. 1 032 Chae, J.K. 493 Chaisri, U. 569 Chalikias, G. 657 Chalubinski, M. 518, 801, 828 Chamney, S. 650 Chan, D. 355, 471 Chan, D.C. 394 Chan, J. 357, 885 Bodor, M. 612 Boehm, B.O. 1 065, 1 134 Boeing, H. 412 Boekholdt, S.M. 119, 627, 680 Boeva, O. 848 Bogdan, M. 509 Bogdanska, J. 678, 1 159 Bogniotti, L.A. 1 156 Boileau, C. 946 Boldina, M. 1 231 Bolognese, M. 1 205 Bolotov, I. 510 Bonacina, F. 222, 458 Bonaldo, A. 725 Bonavita, E. 458 599 1 219 Brenner, M.B. Brito Jr, F. Bottazzi, B. 222 Brovin, D. 1 149 Cacciagiú, L. Bottiglieri, T. 277 Brown, A. 349 615 Boucher, P. 283 Brown, M.J. 207 Caceres Gestoso, A. Boudes, P. 244 Brown, M.S. 134 Cadamuro, J. 662 Cahill, P. 476 cai, A. 490 Cai, G. 447 Carreau, V. 946 Caidahl, K. 521 Caruso, D. 267 Cairo, V. 496, 506, 675, 1 050 Caruso, S. 489 Carvalho, L.S. 1 156 Casale, M. 803 Cascales, M.D.M. 508 Boudier, C. 283 Browning, M. 916 Boulanger, C.M. 200 Bruckert, E. Boura, P. 617, 618 1, 53, 69, 229, 244, 365, 946, 976 Bourantas, C.V. 399 Bourbon, M. 360, 730, 857, 901, 943, 945, 955, 959, 985, 993, 996, 1 060, 1 198 Bousquet, K. 186 568, 728, 783, 850, 1 163 1 177 Brugada, R. 1 162 Bruheim, I. 1 118 Caixàs, A. 944 Brunet, A. 463 Cakmak, H.A. Bubnova, M. 982, 998 893, 1 083, 1 150 Buccellati, C. 1 017 Calabrese, G. Buccheri, D. 1 209 Calabresi, L. 416 Casetta, I. 407 47, 121, 650, 963, 1 058 Caslake, M. 1 081 Cassorla, G. 545 187 INDEX Chan, K.C. 247 Chlebus, K. 956 Chang, S.Y. 560 Chlopicki, S. 494 Channon, K. 62 Chmara, M. 956 544, 549, 550 Corrado, E. 1 210 Corral, P. 945, 995 D’Angelo, A. 1 188, 1 189, 1 190 de Gonzalo Calvo, D. Ciffolilli, S. 383 Corrao, G. 911 202 261 D’Angelo, R. 346 Corrêa-Giannella, M.L. 863 D’Erasmo, L. 121 De Gonzalo-Calvo, 1 162 D. D’Agostini, L. 749 de Graaf, J. 244, 270 698 da Silva Rodrigues, E. 972 de Gregorio, C. 803 615 Chao, T.H. 773 Chmelik, Z. 778 Cigankov, V. Chapman, J. 4, 8, 213 Cho, D.H. 884 Cioroch, M. 62 404, 564 Cipollari, E. 697 Cho, J.Y. 738, 739, 1 004 Cipriano Jr, G. 1 178 Corrêa-Giannella, M.L.C. Cipriano Jr., G. 1 177 Correia, E. 1 061 Dąbek, J. 1 071, 1 084 De los Santos Moreno, A. Cho, K.H. 559, 646, 829 Cipriano, G. 1 178 Correig, X. 434 Dadabaeva, N. 744, 752 De Meyer, G.R.Y. 198, 201, 343 Cipriano, P. 1 183 Corsini, A. Dafnis, I. 652 De Michele, M. 544 Cho, S.A. 738, 739 Ciumarnean, L. 1 176 Dahl, M. 834 de Mutsert, R. 113, 293 Cho, Y.K. 1 006 472, 337, 347, 419, 450, 491 Dähnhardt, D. 411 1 216, 1 215 Cho, Y.S. 1 032 Dai, H.L. 1 186 De Nicolás Jiménez, J.M. Choe, N. 350, 371, 1 078 Dalan, R. 881, 1 065, 1 134 de Roos, A. 113, 293 De Soysa, M. 936 Charakida, M. 188 Cifani, N. 719 Charania, S. 502 Charrière, S. 625, 1 057 Chasiotis, V. 736 Chatzigeorgiou, M. 762 Cho, H.C. Chatzizisis, Y. 93 Chaudhary, R. 417 Chaudhuri, S. 933 Chawla, P. 1 062 Chechetkin, A. 598, 602 Choi Wan, J.F. 994 Chee, Y.J. 881 Choi, B. Chen, C.H. 348 Chen, H. 107, 1 028 Chen, H.T. 341 Chen, Y. 524 Chen, Y.R. 453 Cheng, L.I. 1 009 Cheol-Young, P. 115, 202, 358, 765, 766, 921, 971, 975 Cosansu, K. 1 150 Cosentino, N. 530 Cosic, V. 1 217 Clapp, W. 107 Coskun, E. 1 175 Dalla-Riva, J. 408 De Vries, J.K. 413 1 094 Clara, J. 48 Coskunpinar, E. 1 083 Dallegri, F. 407 de Vries, T. 399 Choi, B.G. 1 000 Clouet Foraison, N. 634 Cosor, O.C. 769 Dallinga-Thie, G. 97, 260, 331 De Vuono, S. 849, 865 Choi, B.H. 404, 564 Coassin, S. 1 079 Cossette, M. 696 Dallinga-Thie, G.M. 286, 1 054 de Winther, M. 556, 704 Choi, B.M. 439 Cobbaert, C. 578, 634 Costabile, G. 1 183 Dalton, N. 455 Deanfield, J. 719 120, 1 000, 1 185 Cocci, G. 1 161 Coughlin, P.A. 743 814 Dechkhajorn, W. 569 Cochran, B. 342 Couture, P. 976 417 Deev, A. 734, 735 Choi, J.H. 761 Codogno, I. 474 Craiem, D. 754 Dancer, M. 1 057 Degoricija, V. 707 1 202 Choi, J.Y. 1 001 Colaço, I. 742, 941 Cramb, R. 666, 930 Danielsson, A. 290 Dehoux, M. 474 Chernatskaya, O. 1 187 Choi, M.H. 120 Cole, A. 93 Crasborn, M. 556 Danzl, K. 477, 504 Del Bo’, C. 1 105 Cherng, J.Y. 1 126 Choi, Y.J. 244 Colhoun, H. 308, 310 Darabi, M. 104, 711 82 604, 605 Chong-Yang, D. 902 Colhoun, H.M. 246, 463 835, 836, 837 Del Core, M. Chernyavina, A. Crespín Crespín, M. Chestnutt, J. 650 Chora, J. 945 959 1 176 Chora, J.R. 955, 1 060 995 609, 792 544, 549, 550 Cristaldi, A. Dascalescu, R. Cheta, I. Colima Fausto, A.G. 267 676 Del Porto, F. Crestani, M. Das, S. 1 043 452 634 Cristescu, C. Daskalopoulou, S.S. Delatour, V. 530 Delbridge, L. 223 488, 523, 701 Choi, C.U. Civeira, F. Damasceno, N.R.T. Chétiveaux, M. 648 Chou, C.H. 919 Colli, S. Chew, D. 1 065 Chowdhury, M.M. 743 Colombo, G. 1 034 Croce, K. 93 Dasseux, J.L. 714 Deleanu, M. Chew, D.E. 1 134 Christen, T. 293 Coman, S. 775 Croyal, M. 648 Datta, H. 988 Delgado-Coello, B. 64 chi, Y. 524 Christie, B. 677 Compte, M.T. 434 Cruciani, G. 383 Dattilo, G. 803 Delgado, G.E. 1 146 Chia-Yin, T. 1 064 Christoffersen, C. 717 Conceição, R. 920 Cruz, D. 742, 941 Daunoravicius, Z. 1 072 Dell’Oca, N. 945 Chia, Y.C. 1 207 Christomanou, H. 1 059 Concin, H. 770 Cuchel, M. 430 Dauteuille, C. 104, 711 Dell’Oglio, S. 1 209 Chiappa, G. 1 177, 1 178 Chroni, A. 652 Cong, K. 651 Cuenca, N. 938 Davel, A. 827 Dell’Oca, N. 961 Chiara, M. 372 Chrysohoou, C. 762, 846 Connell, P. 1 133 Cuesta Torres, L.F. 342 Davì, G. 1 033 Dellera, F. 1 113 Cuevas, A. 945 131, 372, 511, 639, 689, 1 118 Chiariello, C. 626 Chuang, C.K. 210 Connor, T. Davids, J. 1 028 Chicheva, M. 1 066 Chudinovskikh, T. 1 110 Conrad, D.H. 307 Curran, J. 449 Davidson, M. 464 Chung, S.M. 1 185 705 Cursaru, A. 805 1 074 131, 372, 511, 639, 689, 1 118 Constantin, G. Demakova, N. Chiesa, G. de Boer, H. 269 512, 1 010 Constantin, G.I. 802 Cutuli, L. 222 546, 1 016 Chung, W.Y. de Boer, J.F. 804 Dembinska-Kiec, A. Chvostova, M. 568 Constantinou, C. 688 Czarnecka, D. 931 De Boever, P. 502, 514 DeMicco, D. 119 Ciba, P. 1 157 CONTAMIN, H. 292 Cziraki, A. 414 de Bruin, R.G. 269, 483 Demikhova, N. 1 187 Cibickova, L. 635 Conte, C. 496 D de Bruin, T. 464 Demina, E. 890 Cicala, V. 1 183 Cook, E. 209 D’Acierno, L. 924, 925 De Fabiani, E. 267 Demina, M. 911 Cicero, A. 380, 391, 1 022 Cook, E.C.L. 664 D’Addato, S. De Faria, E. 922, 983 Demir, M. 984 Cooper, A. 1 113 380, 391, 671, 749 de Feyter, P.J. 399 Demircioglu, S. 984 671, 749 Cooper, J. 934, 952 De Geest, B. 126, 655 Demopoulos, C. 1 115 Chillarón, J.J. 1 012 Ching, S.M. 1 207 Chinnasamy, P. 94 Chiong, C. 881 Chiou, H.Y. 1 089, 1 184 Chiu, T.Y. 341 Chiva-Blanch, G. 1 102 Cicero, A.F.G. D’Agostini, L. 671 189 INDEX Demuth, I. 935, 1 087 Dixon, S. 401 Dritsa, V. 813 El Khoury, P. 946 Esteve, E. 944 Fellin, R. 121 Denby, L. 1 081 Djaramshi, A. 269 Drogari, E. 1 059 El-Kersh, A. 797 Estruch-Alrich, M. 876 Fellnerova, A. 939 Dengxuan, W. 902 Djeric, M. 870, 1 095 Dronca, E. 913 El-Osta, A. Etxebarria, A. 527 1 042 Djokic, V. 821 Dropinski, J. Ferin, R. 1 155 Denney, L. 667, 910 Djordjevic, V. 1 217 796, 840, 841 637, 985, 1 056 Fenyo, I.M. Denisenko, M. 35, 239, 265, 1 113 El-Zidy Ibrahim, N. 989 Eun Seoung, L. 552 Ferlin, A. 725 Dent, R. 392, 462, 1 009 Dlouha, D. 683, 939 Drosos, I. 657 El-Zidy-Ibrahim, N. 935 Evangelakos, I. 437 312 Dobrolubov, M. 613 Druina, L. 598, 602 Elbahey, M. 587, 790 Evdokimenko, A. Deon, V. 1 105 Doganci, S. 294 Du, X.J. 223 Elbaz, M. 346 500, 598, 602 FernandezHernando, C. 960 Doi, M. 586 Du, Y. 339 Elbitar, S. 946 Even, G. 474 FernándezHiguero, J.A. 637 Derfler, K. Derosa, G. 1 188, 1 189, 1 190 DOKMEN, H. 951 Duarte, T. 742 Elena, M. 555 Everson, F. 514 Dokoza Terešak, S. 707 742, 941 Elfaleh, E. 909 Evola, S. 819, 1 210 Fernández-Miró, M. 1 012 Ducla Soares, J.L. 269 Eligini, S. 530 Evola, V. 819 774 622 Duijs, J. Fernández, E. Doktorova, M. Duivenvoorden, W. 1 173 477 Dumitrescu, A. 769, 1 046 606, 685, 686, 687 267 796, 840, 841, 1 008 Dumfarth, J. Ferrari, A. Domagala, T. 432, 709, 753, 928, 977, 978, 1 003 961 480, 494 818 Fernandez, G. Dolezelova, E. Exarchos, T. Ferrari, R. 1 022 Domingo-Espin, J. 408 Dumitriu, I.E. 40, 459 947 Ferreira, G.S. 698 Elizova, N. 532, 632 Domingues, C. 592 Dunaeva, A. 907 F Ferreira, J. 592 Ellena, R. 651 Dominguez Crespo Hirata, R. 972 Dunaway, C. 94 531 Ferreira, M.J. 592 Ellis, K. 355 Fabres Machado, U. Durmus, R. 984 Ferreira, R. 843 Elnour, A. 1 181, 1 182 Fabris, F. 725, 1 029 Durrington, P.N. 426 Ferreira, S. 1 155 Emese, T. 475 Faccini, J. 346 Dürschmied, D. 470 Ferrer, R. 425 Emich-Widera, E. 1 218 Fagg, W.S. 269 Duta-Mare, M.C. 443 Ferri, L. Emma, K. 47 Faggiano, P. 1 179 544, 549, 550 Dwivedi, O. 354 Empana, J.P. 1 196 Fahey, T. 980 Ferri, N. Dwyer, T. 758 Emukhvari, M. 844 Fainardi, E. 407 337, 347, 419, 472 Dybvig, A. 684 Endo, Y. 1 049 Fajkusova, L. 973 Figueras, R. 944 480, 494 Descamps, O. 976 Deschildre, C. 474 Deshpande, A. 1 062 Deshpande, S. 1 009 Després, J.P. 3, 7, 212, 214, 387 Dhar, I. 779 Dhawan, V. 722 Dhyani, A. 472, 554, 1 063 Dominguez Crespo Hirata, T. 972 803 Donato, P. 592 Di Bella, G. DI CATALDO, V. 292 Dong Il, S. 1 200 Di Filippo, M. 1 057, 625 Dong Ju, C. 1 200 di Gioia, C. 549 Dong Soo, K. 1 200 di Giuseppe, R. 412 Doni, A. 222 Donn, R. 426 Di Taranto, M.D. 958 Diana, S. 476 DiCioccio, A.T. 463 Dickerhof, N. 1 127 Didangelos, T. 736 Didenko, Y. 783 Dienova, J. 1 121 Dieplinger, B. 460, 882, 1 154 Dieplinger, H. 704 Doppler, C. 477 Dorel P., S. 913 Dorofeeva, Y. 1 191 Dostal, E. 541, 720 Douglas, G. 62, 349 Douglas, S. 969 Doulamis, I. 382, 1 119 Downie, P. 969, 1 051 Ezhov, M.V. Engberg, S. 209 Falcou, A. 544 Eak Kyun, S. 1 130 Enguita, F. 996 Falk, E. 1 164 Filatova, A. 551 Eastwood, J. 1 081 Enikő, B. 475 Fang-I, H. 453, 1 064 Filipovic, N. 818 Ebenbauer, B. 418 Enko, D. 1 143 Faraj, T. 525 Filippova, A. 497 Ebtehaj, S. 47, 699 Eom, G.H. 350, 1 078 Farajian, P. 1 092 Filou, S. 688 Eckardt, K.U. 278 epstein, J. 1 101 Farhoudi, M. 600 Fimiani, F. 924, 925 Edelberg, J. 246 Erdmann, J. 240, 1 157 Faria, F. 742, 941 Fiorelli, S. 530 Edholm, D. 1 116 Eremic, N. 1 095 Faria, R. 1 061 Fiorentini, C. 818 Edsfeldt, A. 290 Eretova, Z. 683 Farinaro, E. 67 Fiorino, E. 267 EFECTL Study Investigators, G. 461 Eriksson, M. 89, 1 027 Farnier, M. Fischer, A. 333 Eriksson, M.J. 521 246, 389, 463, 976 Fischer, A.W. 88 1 194 Fischer, M. 418 377, 1 069 Doytcheva, P. 719 Efstathiou, S. 1 092 Dikkers, A. 47 Dr. Dostal, E. 1 145 Egbung, G. 1 124 Dimakopoulos, I. 1 092 Dr. Gruber, K. 1 145 Eggertsen, G. 376 Dimitriou, T. 977, 978, 1 003 Dragut, R. 805 Eha, J. 1 129 Drechsler, C. 1 192 Ehrenborg, E. Dimova, L.G. 804 Dressel, A. 396 Dimulescu, D.R. 1 082 Drettwan, D. Dincgez Cakmak, B. 893 Drexel, H. Dissanayake, S. 994 544, 549, 550 Ezhov, M. Fikrova, P. Dietel, B. Dito, R. 190 17, 23, 31, 411, 1 154 Donners, M. E Elisaf, M. Eriksson, P. 521 Fatima, A. Ermina, M. 568, 728, 850, 1 163 Faus-Dader, M.J. 866 Fischer, S. 403, 682 Faussner, A. 305 Fiser, A. 94 EROGLU, Z. 953, 951 Favari, E. 697, 1 058 Fitzpatrick, E. 476 203 Erridge, C. 525 Favretto, S. 599 Flachs, P. 889, 892 Eichmann, T. 374 90 Erskine, N. 757 Fayer, F. 954, 1 169 Fletcher, J. 545 Eichmann, T.O. 284 366, 731, 732, 733, 839, 879, 883, 991, 1 067, 1 136, 1 137, 1 138 Erturk, M. 893 fazali, M. 1 223 1 012 Ekici, A. 1 069 Escalante, F. 959 Febbraio, M. 223 Flores Le-Roux, J.A. Ekroos, K. 131, 275, 639 Escolà-Gil, J.C. 384 Fedak, D. 903 Flugelman, M.Y. 932 El Asmar, Z. 283 Espinosa, E. 1 161 Federico, V. 818 Fogacci, F. 391, 671, 749 El Bounkari, O. 291 Essop, F. 502 Felder, T. 662 Föger, B. 219 El Eter, E. 1 193 Fomin, I. 1 231 191 INDEX Fonseca, R. 843 Fuentes, L. 651 Garaffa, C. 924, 925 Genser, B. 699 Fontes, A. 1 155 Fuertes, R. 434 Garaffa, E. 924, 925 Gentili, A. 849 Foody, J. 389 Fuior, E.V. 527, 1 085 Garces-Horna, V. 505 Georgiadis, I. 1 119 Forbes, C. 1 009 Fujita, Y. 636 García Fuertes, D. 725 Fülöp, P. 435, 467, 702, 1 151, 1 153 835, 836, 837 Georgousopoulou, E. 762, 846 Foresta, C. Garcia Garcia, H.M. 399 Gerard, W. 449 García León, A. 384 Gerdes, N. 128, 305 García-Arnés, J. 428 Gergei, I. 396 GarciaCampanario, I. 1 099, 1 109 Gerothanassis, I. 1 128 Gesheff, M.G. 417 García-Casares, N. 428 Ghabili, K. García-García, I. 938 Garcia-Vaz, E. 114 Fort, J.M. 425 Fortini, F. 1 022 Fortunato, G. 958 Foryst-Ludwig, A. 285 Fotiadis, D. 818 1 069 Furukawa, L. 1 122 Furusyo, N. 579, 610, 727, 755, 756, 905 Fotiadis, D.I. 399 Fourie, C.M. 619 Fusaro, M. 1 029 Fournier, N. 691 Fusco, F. 1 122 Fraass, U. 396 Futema, M. 952 Fragopoulou, E. 1 117 G Fragoso, J.M. 356 Gabbasov, Z. 473, 853 Fragouli, S. 382 Gabcova, D. 1 052 France, M. 426 Gabriel, D. 827 Franceschini, G. 650 Gabrielyan, D. 850 Franck, G. 93 Gabrielyan, L. 850 Franco-Cereceda, A. 521 Gaetano, C. Frank, S. 192 Furtmair, R. 374, 422, 499, 707 Franz, R. 48 Franzese, C.J. 417 Frascaroli, C. 276 Fraser, B. 758 Fraunberger, P. 1 067 Freiberger, T. 962, 973 Frias, M. 710 Fried, S. 281 Frikke-Schmidt, R. 237, 1 080 Frimmel, K. 565, 1 015, 1 121 Garcia, A. 1 162 Garcia, I. 904 Gareeva, D. 745 Giyazitdinova, E. 597, 726, 787, 788, 831, 979, 1 025, 1 132 Gonzalez-Calero, L. 129 GonzalezJuanatey, J.R. 1 162 Gkougkourelas, I. 617, 618 1 035 González-Santos, P. 428 Gkourogianni, A. Glazunova, A. 860 Gonzalez, F.J. 375 Glei, M. 383 González, M. 1 123 Glerup, S. 332 Goodwin, M. 694 Głodzik, J. 585 Goossens, P. 704 817 Głogowska-Ligus, J. 1 071, 1 084 Góralska, J. 546, 1 016 Ghaleb, Y. 946 Gordts, P. 44, 46 Godber, I. 1 081 Ghanaati, H. 580, 607 Gorzelak-Pabis, P. 518 Göderle, L. 307 Gharipour, M. 1 197, 806 Gorzelak, P. 801, 828 Goebel, G. 503 Gheysens, O. 655 Goswami, N. 502, 514 Goedecke, J. 710 Ghezaiel, S. 858, 859, 1 174 Gottschling, K. 333 Goedeke, L. 312 Goudevenos, I. 1 035 Goeritzer, M. 284, 622 Goulas, A. 1 088 Goettsch, C. 42 Goumas, G. 1 092 Goh, L.L. 1 065, 1 134 Gouni-Berthold, I. 669 Gojazadeh, M. 817 Gouveia, C. 843 Gojkovic-Bukarica, L. 821 Govorin, A. 807 Gojković, T. 436, 741, 874 Gracia, M. 754, 774 Goldberg, R. 757 Græsdal, A. 684 Goldstein, J.A. 401 Graham, I. 319 Goliasch, G. 541 Graier, W.F. 284 Golledge, J. 362 Grallert, H. 313 Golubenko, M. 1 070 Grammer, T. 396, 937 Gomaraschi, M. 47, 386, 1 058 Grammer, T.B. 409, 1 146 Granata, A. 450 380, 671 Garjani, A. 566 Garlanda, C. 222, 458 Ghezzi, M. 725 Garlaschelli, K. 238, 616, 898, 1 063 Ghoneem, A. 587 Ghorashi, S. 817 Garlick, J. 723, 1 206 218, 221 Ghosh Laskar, M. 336 Garnier, J.M. 283 Gafane, L. 619 Giacco, A. 1 183 Garolera, M. 938 Gafarov, V. 795 Giacobbe, C. 958 Garzillo, C. 781 Gafarova, A. 795 Giammanco, A. 1 169 Gasbarrino, K. 452 Gafencu, A.V. 527, 1 085 Giannella Neto, D. 863 Gasco, A. 491 Gagulin, I. 795 Giannini, S. 1 029 Gąsior, Z. 1 071, 1 084 Gaita, D. 769, 1 046 Gibbs, J. 976 Gasko, R. 635 Gaita, L. 769, 1 046 Gieger, C. 313 Gaspar, G. 857 Galabova, G. 245 Gijbels, M. 704 Gaspar, L. 541 Galicia, U. 1 056 Gilham, D. 118 Gasperikova, D. 1 052 Galimskaya, V. 589, 590 Gill, S. 897 Gomes, A. 592 Grandi, E. Gast, K.B. 293 Gomes, D. 1 122 735 1 075 349 Gratsiansky, N. Galitsyna, E. Gillard, J. Gaston, A.T. 474 Gomes, D.J. 698 944 365 634 Grau, J. Gall, J. Gillery, P. Gaudet, D. 505 Gomes, E.I. 983 497 114 Gimenez-Lopez, I. Grechanyk, N. Gallagher, J. 59, 244, 247, 300, 353, 660, 669, 1 053 Gingell, R. 936, 990 Gomes, I. 1 198 Greco, D. 692, 715 Ginsberg, H. 714 Gomes, M. 270 Green, S. 673 Gautier, E.L. 104 Giollo, L. 1 178 904 Grenkowtiz, T. 935 Gavriil, L. 1 117 Giordano, P. 1 161 Gomez -Villarejo, D. Greter, M. 127 114 Greve, J.W. 113 Frisdal, E. 365 Galli, F. 383 Fritsch, H. 22 Gallieni, M. 1 029 Fritsche, A. 412 Gallivan, A. 952 Fritz, J. 770 Galy, B. 102 Froemming, G.A. 485, 486, 487 Gandra, S.R. 392, 1 009 Ganesan, M. 986 Froemming, G.R.A. 1 211 Ganiev, U. Froio, A. 511 Froněk, J. 562, 535 Fruttero, R. 491 Frutuoso, J. 730, 901 Fu, J. 5, 9, 113 Fuentes, J. 1 028 629, 640, 663 Giorgini, M. 1 183 Gomez, M.F. Giovannini, M. 671, 749 Gonçalves, C. 799 Griffin, J. 969 Gaye, B. 1 196 247 GONCALVES, F. 522 Griffo, E. 1 183 1 195 Gipe, D.A. Gebhard, C. 696 Griffo, R. 1 179 571 365 290 Ganiyev, U. Giral, P. Gonçalves, I. GELOEN, A. 292 592 Grigore, L. 131, 372, 511, 639, 689, 1 118 434 Gonçalves, L. Ganzetti, G.S. Giralt, M. Gelosa, P. 1 039 Girona, J. 393 Goncharova, I. 1 070 238, 616, 898, 1 063 Genest, J. 714 Giulietti, F. 1 161 959 Grigorie, M. 705 881, 1 065, 1 134 Genis, A. 514 238, 898 Grimm, M. 351 Genkel, V. 1 042 Giuseppe Danilo, N. González Garcia, J.R. Gonzalez Marines, D. 959 Gritskevich, A. 906, 911 Grivel, J.C. 548, 1 047 Gao, X. Gapon, L. 538, 557 Gavrilova, N. Gennaro, A. 818 193 INDEX Groen, A.K. 210, 622 Gurvich, E. 1 231 Harvey, D. 952 Hernandez, M. 522 Hong, S.P. 1 001 Huisman, H.W. 619 Gromova, E. 795 Gustafsen, C. 332 662 Hernández, M.P. 478 Hong, T.J. 761 Huitema, L. 704 Grönlund, C. 596 Gustafsson, P. 203 Haschke-Becher, E. Herrera, M.D. 381, 1 125 hongyu, W. 809 Hukkanen, M. 915 Groop, L. 354 Gustafsson, U. 1 027 Hashida, T. 1 002 Herz, C. 507, 772 481 Hulett, M. 489 Groothoff, J. 968 428 Hatsukami, T. 248 Herz, C.T. 771, 1 147 Humphries, S. 238, 934 Grosu, L. 805 Gutiérrez-Cardo, A. Hoogenboezem, M. Hattori, T. 899 Herz, J. Hoogeveen, R. 677 Humphries, S.E. 952 Gruca, A. 1 016 Guyer, K.E. 417 Hatzitolios, A. Hooper, A. 355 Hung-Yi, C. 453, 1 064 Gruchala, M. 956 Gyrasis, C. 399 617, 618, 736, 1 088 41, 91, 283, 469 Hetjens, S. 274 Hopmans, S. 1 173 290 H 794 455, 673 Grufman, H. Hatzitolios, I.A. Hung, M.Y. Heywood, S. 223 Hoppstaedter, J. 492 1 199 Ha, K.H. 729 708 82 Grujic Ilic, G. Haupt, C. Hunter, W. Hiebert, S.W. 267 Hörauf, A. 377 285 Haas, G.M. Hilgendorf, I. 949 Havulinna, A.S. 410 Hurme, R. 275, 639 654 224, 306, 470 Hori, M. Gu, J. 368, 438, 1 098 547 420 Grune, J. Havik, S. Hur, S.K. Horinek, A. 962 393 448 Hayashi, J. Hilvo, M. 131, 275, 639 Horn, J. 651 1 011 Hinterreiter, F. 882 1 096 1 186 Habibinejad, H. Husche, C. Guang, X.F. Horner, D.S. 372 Hippe, D. 248 249 958 1 106 Husebye, E.S. Guaraldi, F. Haddad, E. 579, 610, 727, 755, 756, 905 47 Guaita, S. Haase, M. Hurt-Camejo, E. Host, L. 283 958, 987, 1 058, 1 105, 1 180 1 096 Hiraoka, Y. 1 002 622 Guardamagna, O. Haenen, G. Hussain, M.M. Hottiger, M.O. 127 Haerdtner, C. 306 743 700 42 Hayes, P.D. Hirata, H. Hutcheson, J. Hou, J. 873 Hafner, E. 1 154 83 338 942 He, B. Hirata, K. Hutchings, A. Hou, L. 342 88, 331, 333, 334 972 411 Heeren, J. Hiroyuki Hirata, M. Huth, C. Hovingh, G.K. Hisakawa, N. 561 119, 286, 359, 392, 627, 680, 974, 976 Hutten, B. 968 Huttl, M. 661 Huynh, K. 314 Hovingh, K. 331 Hwang, S.H. 738, 739 Hovland, A. 466, 864 Hwang, Y.C. 1 202 Howanietz, M.T. 771 Hyeon Gheol, G. 1 200 Hoxha, M. 1 017 Hyo Sang, H. 1 201 Hrelia, S. 1 022 Hyuck Moon, K. 1 200 Hryachkova, O. 573 Hyun Woo, P. 1 130 374 Hyun, M.H. 1 000, 1 185 484, 838, 854 Guardigli, M. 1 022 Hagemeyer, C. 223, 273 Guarini, P. 626, 656 Hagger, M. 1 168 Guarnieri, F. 981, 1 166, 1 167 Hahn, R.T. 492 Heestermans, M. 1 040 Hjellestad, I.D. 249 Haikal, A. 910 Heikkilä, H. 354 Hmaidi, W. 1 091, 1 111 Hakimjavadi, R. 476 Heikkilä, T. 690 Ho-Jun, J. 1 130 Hakovirta, H. 423 Heimann, J. 1 122 Ho, H.H. 348 Hale, A. 62 Hein, L. 306 Ho, J. 426 Halliday, C. 118 Heine, M. 88, 333 Ho, Y.C. 348 Hallström, S. 499 Heinemann, A. 1 030 Höbaus, C. Halmurat, U. 1 090 Heinle, H. 821 507, 771, 772, 1 147 Halon, D.A. 932 Heinonen, S. 446 Hobbs, H. 32 Hrzenjak, A. 916 Hsieh, F.I. 1 089, 1 184 I 71 Hsin-Chiao, W. 453 Iaconi, M. 549, 550 105, 1 014 IBAROLLA, D. 292 Guðnason, V. 1 220 Guedes, J. 1 061 Guerado Espinosa, I. 835, 836, 837 Guerin, M. 365 Guerra, A. 1 060 Guerrasio, A. 276 Guerrini, U. 458 Guertin, M.C. 696 Guervazoni, A. 1 177 Guibout, C. 1 196 Guillas-Baudouin, I. 104 Guizoni, D. 827 Han, S.H. Gulevskaya, T. 500, 500, 598, 602 Guljas, S. 1 160 Gulkevych, O. 811 Gunasekar, P. 82 Gundry, S. 519, 1 101 Guo, W. 534 Gurbel, P.A. 417 Haltmayer, M. 882 Heintjes, E. 760 Hobkir, J. Hama, S. 426 Heinz, K. 477 Hoefer, I. Hamed, W. 797 1 098 Hoefler, G. 284, 622 Hsu, L.W. Hoeke, G. 90 Hsu, P.L. 445 Ibarretxe, D. 393 357, 885 Ibe, N. 641 Hammad, B. 587, 790 HeinzelGutenbrunner, M. Hammami, S. 1 174 Helk, O. 960, 1 107 Hoeksema, M. 704 Hu, M. 317, 326 Hua-Long, L. 902 Iborra, R.T. 698 385 Huang, C.F. 1 089 Ibrahim, Z. 923 Hubacek, J. 724, 939, 962, 1 068 Idzior-Waluś, B. 903, 931, 912 Igari, K. 1 148 Hubacek, J.A. 871 Igelseder, B. 503 Huber, K. 418, 541 Igland, J. 957 Hübner, M. 377 Ijäs, P. 354 Huby, T. 104 Ikaida, M. 620 Huckova, M. 1 052 Ikeda, Y. 561 Hudiakova, N. 842 Ikegami, Y. 537, 1 141 Hughes, A.D. 312 Ikemura, N. 537, 1 141 Hughes, L. 988 Ikewaki, K. Hughes, S.G. 669 693, 700, 1 049 Hui, D. 331 Ikhlef, S. 110 1 200, 1 201 Henkel, V.V. 947 Hoes, A.A.W. Handru, M. 1 176 Hennig, B. 385, 1 093 Hoffman, J. Hanna, E. 650 Henstridge, D. 223 Hoffmann, M.M. 409 121, 344, 390, 949, 976 Hentze, M.W. 102 Hofker, M. 113 Heras, M. 393 Høgh, A. 834 Herder, C. 411 Hoh, B.P. 681 Harada, A. 338 Heredero, A. 129 Hohensinner, P. 418 Harangi, M. 435, 467, 612, 702, 1 153 Herings, R. 760 Hollstein, T. 989, 1 087 Hermann, M. 649 Holmes, E. 988 578 Holven, K.B. 957 Harada-Shiba, M. Gurevich, V. 400 Hargrave, G. 498 Hermans, M. Gurevich, V.S. 718, 947 Harrison, S.C. 743 Hernandez Flores, T. 959 HernándezMijares, A. 866 Gurlek, A. 194 Hayashi, T. 715 Hart, L. 969 Gurses, K.M. 294, 715 Hartgers, M.L. 359, 974 Gursky, O. 630, 708 Hartvigsen, K. 307 Honarpour, N. 465, 976 Hong, B. 339, 695 Hong, S.J. 738, 739, 1 004 195 INDEX Ikonen, E. 915 Jalkanen, S. 423 Jones, A.F. 666 Kalkavouri, A. 736 Kastelein, J. 119, 244, 390 Khan, F. 114, 289 Ilina, N. 606 James, R. 710 Jones, G. 1 127 122 Kastelein, J.J. 463 Khanal, M.P. 659 Ilincic, B. 870, 1 095 Janabaev, B. 851, 861 Jones, J. 889 Kalminaovska Oštrić, D. Kastl, S. 541 Kharazmi, F. 1 223 Illyes, M. 414 Janczura, M. Jones, R. 362 Kals, J. 1 129 Katano, H. 593 Khasanova, Z. 1 077 Ilyin, A. 860, 900 796, 840, 841, 1 008 446 Kamenihina, I. 454 Katarzyna, G. 801 Khaw, K.T. 627, 680 Imamura, S. 621 Jänis, M. 131 Jönsson-Rylander, A.C. Kamiyama, Y. 1 041 Kathiresan, S. 946 Kheder, R. 916 Imbalzano, E. 496, 506, 588, 675, 803, 1 050 Jannes, C. 945 Jonung, T. 249 Kammoun, H. 223 Katkó, M. 702 Khedher, S. 1 171, 1 172 Janovska, P. 889 Joo, H.J. Kamphuisen, P.W. 413 Kato, Y. 859 765, 971 Kamran, M. 1 223 Ina, K. 484, 838, 854 808 Joo, N.S. 1 094 Khiari, K. Jargin, S. Kang, B.G. 1 004 579, 610, 727, 755, 756, 905 Khessairi, N. Jarauta, E. 738, 739, 1 004 858, 859, 867, 909 599 106, 270 Kang, D.O. 120 Katsilambros, N. 1 119 948 Jaroch, J. Joosten, L. Inazu, A. Khokhlov, L. 750 556 Kanjuh, V. 821 Katsilambros, Ν. 382 893 903 Joosten, S. Inci Coskun, E. Jasik, P. Khokhlov, R. 750 48 Kanthasamy, V. 897 Kaudewitz, D. 312 954 Khoury, É. 247 Jørgensen, A.B. 237 780 275 855 Kapoor, S. Kauhanen, D. Inoue, Y. Khromova, A. 591, 603 Joris, P.J. 1 100 903, 912, 931 418, 720 1 149 Kapusta, M. Kaun, C. Ionin, V. 623, 111, 286, 354, 378, 384, 442, 652, 690 Jörg, H. Ingrassia, V. Jauhiainen, M. Khurana, I. 239, 1 113 Josa-Laorden, C. 505 karakaya, O. 826 Kawakami, K. 855 Kianpour, P. 918 Jouent, X. 1 196 Kararigas, G. 76 Kawasaki, M. 642 Kiechl, S. Jovanova, S. 678, 1 159 Karasek, D. 635 Kawase, R. 63, 395, 653 312, 411, 1 229 Ju Won, S. 552 Karatzas, K. 794 Kawashiri, M.A. 948 Kiemer, A.K. 492 Juhász, I. 1 151 Karavia, E. 688 Kaya Kocabas, E. 953 Kikas, P. 657 Jukema, J.W. 245, 269, 293 Karbiener, M. 894 Kaya, E. 294 Kikuchi, H. 457 Karciauskaite, D. 1 072 Kayikcioglu, M. 953 Kim, B. 751 Kardassis, D. 130, 206, 437, 527, 1 085 Kayıkcıoglu, M. 951, 984 Kim, B.W. 761 Kaynar, L. 984 Kim, C.G. 398 Kazan, H. 269 Kim, C.J. 999 Kazdova, L. 421, 661, 877, 895 Kim, D.J. 729 Kim, D.W. 398 622 Jay-Christian, H. 476 Irina, O. 538 Jayaraman, S. 630, 708 Irino, Y. 338 Jazet, I. 90 Isermann, B. 412, 669 Jean-Charles, G. 555 Ishida, T. 338 Jebari, S. Ishizuka, M. 1 049 Jelev, D. isikssacan, N. 826 Jelić Ivanović, Z. Ismail, N.H. 485 Jelić-Ivanović, Z. Ismail, Z. 965 Isomäki, A. Iqbal, J. 917 122 Jukema, W. 113, 446, 578 436, 741, 874 Jula, A. 354 Jeney, V. 475 Julius, U. 403, 682 915 Jenkinson, F. 988 Julve, J. Kari, A. 220 Ito, H. 586 Jensen, E. 389 384, 425, 944 Karimova, M. 209 Ito, M. 1 049 Jensen, G.B. 427 Jumaa, H. 307 Karlafti, E. 736 Kebryakov, A. 728, 1 163 620 332 Jung Won, S. 1 200 1 078 Ito, Y. Jensen, S.L. Kim, E. Karlsson, T. 367 Kedenko, I. 1 079 Ivandaev, A. 793, 906, 911 Jenty, M. 283 Jung, C.H. 405, 737 Kim, E.J. Karolina, R. 801 Kedenko, L. 120, 1 000, 1 185 Ivanoshchuk, D. 832, 929, 940, 964 Jeon, S.M. 1 004 Jung, S.I. 1 094 Karonova, T. 1 149 411, 503, 662, 1 079 Kim, E.M. 350, 371 Jeong, S.J. 420, 444 Juno, C. 245 Karpe, F. 85, 86, 89 Keenan, A. 889 Kim, H.C. 729 568, 728, 783, 850, 1 163 Jeonggeun, M. 1 130 Jurado, M.A. 938 Karpov, A. Kelleher, C. 1 031 Kim, H.J. 1 004 Jezkova, K. 494 Justiniano, H. 283 454, 526, 542 Kellici, T. 1 128 Kim, H.K. 120 Ji-Yan, C. 902 K Karpov, Y. 782, 1 139 Kenjaev, M. Kim, H.L. 512, 1 010 Jianbin, Z. 902 Ka Wah, L. 952 Karppinen, S.M. 915 Kim, H.S. 1 010 Jiang, L. 489 Kaaroud, H. 909 Kasatkina, L. 1 203 567, 570, 571, 1 195, 1 221, 1 222 552 822, 824 Kader, T. 1 127 Kaser, S. 503 570 Kim, J.M. Jiang, Y. Kenjaev, S. 764 Kaiser, P. 789 Kashtalap, V. 573, 1 070 980 Kim, J.W. Jiang, Y.D. Kenny, R.A. jinbo, L. 809 Kajani, S. 534 Kasichayanula, S. 976 Kerr, A. 62 120, 1 000, 1 185 Kershaw, E. 285 Kim, J.Y. 559 Kessler, T. 240 Kim, K.C. 404, 564 Keun Ho, P. 1 200 Kim, K.S. 1 001 Keun-Hwa, J. 552 Kim, M.A. 512, 999, 1 010 Keyserling, C. 714 Kim, M.H. 398 Khaitov, S. 1 195 Kim, M.J. Khalikulov, K. 1 204 404, 560, 564 Khalil, A. 110 Kim, N.H. 120 Khallou-Laschet, J. 474 Ivanov, M. Ivanova, O. 548, 555 Ivanova, R. 914, 917 Iwaniec, T. 840, 841, 1 008 Izquierdo, I. 1 162 J Jaceldo-Siegl, K. 1 106 Jinga, M. 805 Kakaletsis, N. 794 Kasim, S. 923 Jacob-Lenet, M.P. 474 Jingwen, L. 337 Käkelä, R. 378 Kasim, S.S. 966 Jacobs, F. 126 Jiyan, C. 490 Kakino, A. 636 Kasimdjanova, G. 744 Jácomo, R. 1 177 Jo, Y.H. 560 Kalbousi, S. 638 Kasimov, U. 851, 861 Jafari Dinani, N. 721 Johansson, J. 118 Kalil, J. 522 Kaski, J.C. 40, 459 918 Jokitalo, E. 204 741, 874 Kaspi, A. 1 113 Jakic, B. 351 Joksić, J. 122 KalimanovskaOštrić, D. Kassner, U. Jalkanen, J. 423 Jon, S. 1 130 Kalkan, A.K. 1 083 935, 989, 1 087 Jafari, R. 196 1 056 197 INDEX Kim, S. 198 405, 444, 493, 737 Kobayashi, J. 621 Koshurnikova, M. 582 Kruse, C. 1 157 Kyounghoon, L. 1 130 Larsson, M. 601 Kobayashi, M. 1 041 Kostaki, S. 794 Krychtiuk, K. 541 Kypreos, K. 688 Laskaris, A. 846 Kim, S.G. 398 Kobayashi, T. 63, 395 Kostara, C. 709 Kubalska, J. 956 Kyselak, O. 950 Lass, A. 284 Kim, S.H. 512, 1 010 Kocabas, E.K. 951 Kostner, G. 135, 263, 960 Kubo, T. 338 Kyung-Hyun, C. 631 Laufs, U. 50, 381, 624 Kim, S.M. 631 Kochueva, M. 869 Kotoulas, C. 813 Kucinskas, V. 1 072 L Laura, T. 118 Kim, W.H. 493 Kocourkova, L. 1 005 Kotseva, K. 73, 116, 769 Kucinskiene, Z.A. 1 072 La Spada, M.P. 954 Lauridsen, B. 211 Kim, Y.C. 1 004 Kocyigit, D. 294, 715 1 069 Laajala, T.D. 378 Laurila, P.P. 111 1 032 Koenig, W. 397 796, 840, 841, 1 008 Kuehn, C. Kim, Y.G. Kotula-Horowitz, K. Kühn, C. 377 Laake, K. 1 102 Laurinavicius, A. 920 Kim, Y.O. 439 Kofoed, K. 211 436 Kuiper, J. 307, 760 Laakso, M. 241 LAVENNE, F. 292 Kim, Y.S. 493, 564 Koike, T. 1 021 Kotur-Stevuljevic, J. Lavie, G. 932 Kolb-Lenz, D. 443 813 131, 275, 639 456 241, 287, 331, 413 Laaksonen, R. Kimura, S. Koutoulakis, E. Kuivenhoven, J.A. Lavier, J. 1 019 457 Kolb, D. 622 1 092 933 Kimura, Y. Koutsouri, A. Labib, M. Kukharchuk, V.V. 947 Lavoie, J.M. 643 223, 314, 362 Koliakos, G. 736 768 866 Kingwell, B. Kouznetsova, T. Labrador-Barba, E. Kulbak, V. 1 023 Lawrence, T. 704 285 Kollerits, B. 411, 1 192 454 678, 1 159 Kintscher, U. Kovalyov, L. Labudovic, D. Kulik, A. 584 666 Komatsu, T. 693, 1 049 454 Lawson, A.J. 1 067 Kovalyova, M. 505 Kinz, E. Kulikowski, E. 118 Lacambra-Blasco, I. 422 Kondo, K. 537, 1 141 Kulkarni, H. 449 Lackman, I. 745 Layland, J. 723, 1 206 Kiriazis, H. 223 König, C. 1 069 65, 96, 111, 230, 354, 378 482 Kirchmair, R. Kovanen, P. Lawson, N. Kumar, P. 847, 1 170 Laclaustra, M. 766 Lazarczyk, M. 800 Kiriyama, M. 338 Konno, S. 899 Kovanen, P.T. 204 Kumar, S. 449 888 Lazzarato, L. 491 Kirsch, A. 422, 499 Konnov, M. 734, 735 Kowala, M. 449 Kume, N. 1 002 Lagares Carballo, M. 503 Kono, H. 457 Kozhanova, A. 793, 906, 911 Kumon, Y. 561 904 292 Kirschner, A. Lagares, M. LE BARS, D. 606 Kono, S. 461 Kozhevnikov, D. 400, 728 Kuo, S.Y. 1 184 408 293 Kiseleva, T. Lagerstedt, J. le Cessie, S. 537, 1 141 Konstantin, D. 418 Koziolova, N. 604, 605 Kupchynskaya, O. 811 508, 1 123 104, 365 Kishimoto, Y. Laguna, J.C. Le Goff, W. 789 Konstantinides, S. 657 Kozireva, A. 728 KURIATA, A. 577 Lebedev, I. 520, 1 086 Kiss, M. 307 382, 1 119 Kozlov, K. 510 Kurilshikov, A. 832 Lebedeva, A. Kitslaar, P.H. 399 Konstantopoulos, P. Kozlov, S. 473, 853 Kurtoglu, E. 984 858, 859, 867, 909, 1 171, 1 172, 1 174 913, 992 Kiss, A. Lahiani, S. Leach, N. 548, 555, 1 047 Kivelä, A. 495 Kontogianni, V. 1 128 Králová Lesná, I. 515, 562, 535 Kurtz, C. 465, 976 Lahoz, C. 766, 921, 975 Lebedeva, N. 868, 1 048 Kjellmo, C.A. 864 Kontush, A. 104, 711 Králová, A. 562, 535 Kuryata, A. 497 Lai, H.Y. 105 Lechleitner, M. 499 Kleber, M.E. 396, 409, 1 146 Kooijman, S. 111, 210 Krämer, B.K. 1 146 Kuryata, O. 786 Lalive, P. 407 Lecorps, G. 463 Kook, H. 350, 371, 1 078 Kraml, P. 517, 558 Kurzejamska, E. 800 Lamari, A. 803 Lecour, S. 710 Krane, V. 1 192 Kutikova, L. 359, 760 Lamb, H. 113 Lecube, A. 425 Krapf, C. 351 kutkiene, S. 784 Lamb, H.J. 293 Lee, E. 1 000 279, 284, 335, 443, 622 Kuznetsov, V. 538, 557 Lambert, G. 119, 209, 645 Lee, E.M. 120 Kuznettsova, T. 997 LAMBERTON, F. 292 Lee, E.Y. 559, 646 Kuzniewski, M. 903 Lamina, C. 411, 1 079 Lee, H.L. 512, 1 010 Kuzuya, M. 484, 838, 854 Lamiquiz Moneo, I. 971 Lee, H.W. 761 Lamiquiz-Moneo, I. 115, 765, 921 Lee, J.B. 1 001 Kleijnen, J. 1 009 Klephortova, I. 860 Kook, T. 371 Klesareva, E. 551, 679 Koolwijk, P. 481 Klevstig, M. 647 Kopecky, C. 699 Klimes, I. 1 052 Kopecky, J. 889, 892 Klinghammer, L. 1 069 Koplyarova, N. 1 163 Krempf, M. 648 Kloch-Badełek, M. 931 Koppensteiner, R. Krempler, F. 1 079 Klopfleisch, R. 285 507, 771, 772, 1 147 Krishnan, A. 767 Kvantaliani, T. 844 Lee, J.E. 884 956 294 619 KłosiewiczLatoszek, L. Kopru, C. Lammertyn, L. Kristensen, T. 211 Kvapil, M. 871 Kopyta, I. 1 218 Lamminmäki, U. 690 Lee, P.T. 773 Kristiansen, K. 889 Kvarnstrom, M. 464 Klotsche, J. 396 Kopytova, A. 740 Landlinger, C. 245 Lee, S. 738, 739, 751 Kristinsdóttir, L.B. 1 220 Kvetnoi, I. 510 Klouras, E. 753, 928, 977, 978, 1 003 Korbelius, M. 335 Langer, A. 1 024 Lee, S.H. 493, 1 004 Krizak, J. 565, 1 015 Kwang Kwon, K. 1 201 Koren, M. 462, 1 205 Langrova, H. 1 026 Lee, S.K. 1 185 Kronenberg, F. Kwang-Yeol, P. 552 Koricanac, G. 373 Langslet, G. 244 Lee, S.N. 748 Kwok, S. 426 Korkusuz, P. 294 Lanska, M. 1 026 Lee, S.R. 493 Kwon, D.H. Kormi, I. 410 18, 28, 241, 278, 295, 309, 411, 1 079, 1 192 350, 371, 1 078 Lanska, V. 724 Lee, S.Y. 120 Korneva, V. 997 Lappegård, K.T. 466, 864 Lee, W.J. 405, 737 Korou, L.M. 382, 1 119 Laringe, M. 924, 925 Lee, Y.B. 439 Koseki, M. 63, 395, 653 Larsson, L. 89 Lee, Y.S. 751, 1 001 Kluge, S. 383 Knezl, V. 565 Knoflach, M. 1 229 Ko, A. 241 Ko, J. 493 Kratky, D. Kroon, J. 81, 481 Krott, L.M. 88 Kruger, R. 619 Kwon, H.M. 665 Kwon, S.U. 763 Kwon, S.W. 665 199 INDEX Lee, Y.U. 350, 371, 1 078 Lim, H.M. 1 207 Lim, W.H. 512, 1 010 Leguina-Ruzzi, A. 478 Lima, A. 1 155, 1 178 Lehti, S. 204 Limon, J. 956 Leighton, B. 446 Limongelli, G. 924, 925 Leiherer, A. 366, 731, 732, 733, 839, 879, 883, 991, 1 067, 1 136, 1 137, 1 138 Lin, S.H. 1 089 Lin, Y.C. 445 Lindahl, M. 408 Leitersdorf, E. 714 Leitges, M. 704 Lek, M. 641 Leoncini, E. 1 022 Leopold, C. 622 Leow, M.K.S. 1 134 Lepore, S.M. 1 055 Leren, T.P. 957, 1 055 Lesnik, P. 104, 365 Letourneur, D. 79, 271 Levels, J. 1 054 Levin, L. 757 Levin, M. 647 Ley, K. 38, 125 Lhomme, M. 104, 711 Li Tin, S.P. 994 LI, B. 723, 1 206 306 Lindholm, B. 47 Lindholt, J.S. 834 435, 467, 612, 702, 1 151, 1 153, 1 227 Machado, U.F. 698 Machida, T. 621 Malinska, H. 421, 661, 877, 895 Margolis, L. 548, 555, 1 047 Macia, A. 1 125 Mallat, Z. 307 mariani, P. 865 Macic-Dzankovic, A. 706 Malyutina, S. 1 212 Marianne, S. Lorkowski, S. 383 1 178 Mamareli, V. 813 Mariano, C. Lorza, E. 827 Maciej, B. 801 Mamarelis, I. 813 943, 993, 1 060 Loßnitzer, D. 274 Loubarinhas, G. 1 060 Maciejczyk, M. 585 Mamone, F. 496, 506, 675, 1 050 Marin, R. 725 Marinova, C. Loureiro, P. 1 198 914, 917 Lövgren, J. 690 Lu, R. 693 Lu, Y.J. 822 Mackēvičs, V. 1 152 MacRae, L. 268 Mancas, S. 769 Markov, A. 1 070, 1 086 Madder, R.D. 401 Manchenko, O. 860 Markova, I. 421, 661, 877 Madero, M. 713 Manchurov, V. 1 047 Markus, H. 48 Madl, T. 443 Mancina, R.M. 1 055 Marlena, B. 801 Mandraffino, G. 496, 506, 588, 675, 1 050 Marmelo, B. 1 061 Marmontel, O. 625 Maroto, A.S. 129 Marott, S. 429 972 Lindqvist, P. 595, 596 Lualdi, A. 1 033, 1 034 Lindsberg, P. 204, 354 Lucas, A. 107, 1 028 284 Liorda, E. 736 MadreiterSokolowski, C.T. Lucena, M. 1 177 Liptak, B. 565 Madsen, L. 889 Lucius, B. 359, 760 Lira, A. 462 Madsen, P. 332 Luczak, E. 518, 801 Lisa M., C. 48 Maegdefessel, L. 264, 266 Ludger, S. 48 Littman, K. 1 027 Maffioli, P. Luetjohann, D. 1 106 1 188, 1 189, 1 190 Liu, C. 695 Luginova, Z. 582 Mafra, J.M. 857 Liu, C.S. 341 Luigi, S. 1 039 959 Liu, D. 362 Luirink, I. 390, 968 Magaña Torres, M.T. liu, H. 809 Luna, A. 1 162 Magaña-Torres, T. 945 Liu, J. 248 Luna, P. 667 Magdalena, C. 801 Liu, P. 695 654 Magné, J. 203 Liu, P.Y. 105, 1 014 LundbyeChristensen, S. Magni, P. Liu, Q. 524 Lundstrom, T. 464 Liu, X. 822, 823, 824 Luongo, D. 1 183 Lupattelli, G. Liu, Y. 426, 902 Manea, V. 862 Maneerat, Y. 569 Manfredi, A.A. 616 Marques Gonçalves, R. Manfredi, M. 626 Marques, B. 1 028 Mangas, A. 888, 904, 1 099, 1 109, 1 162 Marques, N. 1 061 Marsche, G. 374, 440, 707, 1 030 944 Mangels, N. 333 Mangelsdorf, D. 139 Martín-Campos, J.M. Mangge, H. 894, 1 142, 1 143 Martin-Lorenzo, M. 129 337, 386 Mannarino, E. 865 Magnoni, M. 616 Manno, G. Magnussen, C. 758 Manolaki, N. 849, 865 Magomedov, R. 783 Lūriņš, J. 1 152 Mahvi, B. Martin, C. 637, 985, 1 056 1 209 Martin, R. 244 1 059 Martinelli, N. 626, 656 Manolio, T. 34 1 020 Martínez-Marin, M. 505 Mansilha, H. 1 060 Martinez-Marin, R. 505 Martínez-Ramírez, M. 713 Li, J. 524 Li, M. 524 Li, S. 545 Liwen, L. 490 Li, Y. 278 Lüscher, T. 719 Mai, A. 267 Llargués, E. 944 Mansurov, A. 1 204 Li, Y.H. 773 Lüscher, T.F. 127 Maistry, T. 759 Llorente-Cortés, V. 1 162, 202 Mantovani, A. 222, 458 Li, Z. 273 Lutgens, E. 967, 1 160 496, 506, 675 128, 302, 303, 305, 556 Majnaric, L. Lo Gullo, A. Manzato, E. 434 820 121, 725, 1 029 Martínez-Vea, A. Majumder, A.A.S. Martinez, L.O. 101, 281 Makarenkova, K. 929, 940 Martínez, M. 774 Makeeva, O. 1 070 Martinez, P.J. 129 Makino, H. 949 131, 372, 511, 639, 689, 1 118 Makri, E. 617, 618 Maoui, A. 1 171, 1 172 Martinez, T.L.R. 423 1 033, 1 034 981, 1 166, 1 167 Maksimow, M. Mapelli, M. 1 177 626 1 041 Marães, V. Martinotti, S. Makuuchi, A. 1 117 625, 1 057 1 155 Malagaris, I. Marcais, C. Martins, D. 1 165 347 860 Malchikova, S. Marchianò, S. Martynov, S. 1 191 470 548 Malcnikova, S. Marchini, T. Maryukhnich, E. 546, 546, 1 016 Marco-Benedi, V. 115, 765, 975 März, W. 396, 406, 409, 624, 937, 1 146, 1 192 Liamis, G. 753, 977, 978 Libby, P. 93, 306 Lo, W.Y. 810 Lütjohann, D. 1 096 Liberopoulos, E. 753, 928, 977, 978, 1 003 Łoboz-Grudzień, K. 599 Luukkonen, P. 915 Lysne, V. 779 Logunova, N. 782 Licata, V. 954 Lysunets, T. 786 Logvinenko, A. 811, 812 Lichtenstein, A.H. 2, 6, 379 M Løland, K.H. 1 208 Licona-Rashid, M. 717 Lombardi, M. 491 Liem, A. 760 Long, R. 267 Liepold, E. 368, 438, 1 098 Liew, H. 1 065, 1 134 Lim, D.S. 738, 739, 1 004 Lim, H.E. 200 Lindau, A. Lőrincz, H. 1 000, 1 185 Ma, R. 885 Ma, X. 83 Ma, Y. 1 205 Manzini, S. Lopez Tinoco, E. 614 Maas, R. 278 López, G.I. 995 Mabuchi, H. 948 Marcovina, S. 669, 670 Lopez, L.R. 277, 417 MalczewskaMalec, M. Macchi, C. 337 394 1 139 1 178 Marcovina, S.M. Lopukhova, V. Maldaner, V. Mach, F. 58, 60, 407 626 Mas-Oliva, J. 64 209 42 Marengo, E. Loregger, A. Maldonado, N. Machado-Lima, A. 531, 698 Malik, V. 216 Marenzi, G. 530 Masana, L. 121, 393, 944 Machado, F. 961 Mase, M. 593 201 INDEX Masenko, V. 526, 542, 853 Medeiros Bastos, G. 972 Mashele, N. 502 Medeiros, A.M. Masson, G. 93 Mastorakos, G. 382 Masuda, D. 395, 653, 845 Mata, P. 945 Matas, L. 944 Matchin, Y. 686 Mateo-Gallego, R. 115, 765, 766, 921, 971 Mateva, L. Mathisen, M. 864 Matikainen, N. 241 Matmurotov, Q. 851, 861 Matsuda, H. 395, 653 Matsuzawa, Y. 20, 361 Matter, C.M. 127 Matz L., R. Maurer, G. Mauri, M. 202 914, 917 283 418, 541 938, 944 Mavromoustakos, T. 1 128 Mawson, T. 93 Mayer, G. 643 Mayer, L. 1 229 Mayos, J. 944 Mayr, M. 312 Mazeikiene, A. 1 072 Mazzolai, L. 1 019 Mc Crimmon, R. 114 Mehegan, J. Mehrad, H. Meikle, P. Meiler, S. Meinitzer, A. Mieth, M. 278 Migliorino, D. 1 210 360, 943, 945, 955, 985, 1 060 Mignano, A. 1 210 Mijovic, R. 870 1 031 Mika, P. 580, 600, 607, 611, 1 020, 1 037, 1 038 223, 314, 362, 449, 658 441, 485, 487, 716, 923, 965, 966 Motazacker, M.M. 241, 286, 331 N Motilva, M.J. 1 125 Na, J.O. 1 000, 1 185 Motta, B.M. 1 055 Nabika, T. 703, 1 135 681, 716, 965, 966 Moulin, P. 242, 625, 1 057 Nabrozidis, A. 428 584, 585 Mohd Mokhsin, N.A. Nachtigal, P. 480, 494 Mikellidi, A. 1 115 Mohd Nasir, N. 716, 923 Moura, V. 522 Naderi, G.A. 721 Mikhaleva, O. 900 Mohd Nor, F. 681 Mousavi, F. 566 865 Mikic, M. 1 160 Mohtar, F. 1 211 Moxon, J. 362 Naeimi Kararoudi, M. Milaciu, M. 992 Mohtashami, R. 918 Mucher, E. 346 Naessen, T. 601 Milano, G. 450 Mokhort, T. 852 Muckenthaler, M. 102 Nafakhi, H. 887, 891, 896 Milanova, M. 791 Mokhtar, S.S. 681 Mueller, P. 95 Nagai, A. 703, 1 135 882 Nagao, M. 886 366, 731, 839, 991, 1 067 Nagasaka, R. 1 021 Nagel, F. 789 Nagel, G. 770 Nagornova, K. 613 Nagy, E.V. 612 Nahapetyan, H. 346 Nahon, K. 90 Nahrendorf, M. 93 Nair, D. 952 Najib, S. 281 Naka, K.K. 399 Nakagawa, T. 1 021 Nakajima, K. 621 Nakamura, K. 586 Nakandakare, E. 1 122 Nakandakare, E.R. 531, 698 Nakanishi, C. 948 Nakano, Y. 583 Nakata, C. 1 177 Nakatani, K. 395 Nakaya, N. 461 Nakayama, T. 456 Nam, Y.S. 1 078 Nan, R. 805 Narain, R. 815, 816 Narayanaswami, V. 641, 651 Nascimento, T. 781 Nasias, D. 437 Näslund, U. 596 Natale, F. 924, 925 Naumenko, E. 852 Naumov, V. 454, 526, 542 Navarova, J. 565, 1 015 Naviglio, D. 1 183 128, 305 Milicua, J.C.G. 637 Mokhtari-Dizaji, M. 580, 607 Mueller, T. 511, 1 142, 1 143 Milionis, H. 432 Molahedh, Y. 1 091, 1 111 Muendlein, A. Miljkovic, M. 436 Mollaki, V. 1 059 Meisinger, C. 411 Miller, D. 61 Molnár, Á. 1 227 Meitinger, T. 240 Miñambres, I. 876 Mombelli, G. 963 Mekala, A.P. 536 Ming, X. 479 Momiyama, Y. 537, 1 141 Mele, L. 692 Minicocci, I. 121 Monier, S. 711 Melki, A. 867 Ministrini, S. 865 614, 1 109 Mellett, N. 314 Minniti, M.E. 47 Monsalvo Hernando, M. Mellgren, G. 363, 367 Mintz, G.S. 83 888 Mello, A.P.Q. 814, 981, 1 166, 1 167 Miranda, M. 127 MonsalvoHernando, M. Monsalvo, M. Melnichenko, A. 632, 633 Melnikov, I. 473 Melnikov, M. 830 Mels, C.M. 619 Méndez-Acevedo, K. 64 Mensink, R. 340, 1 103 Mensink, R.P. 103, 1 096, 1 100, 1 104 Mirchi, M. 817 Miroshnikova, V. 740, 890 Mishchenko, A. 1 163 Misiano, G. 954 Mistri, A.K. 1 133 Mitish, V. 793 Mitro, N. 267 Mitrofanov, K. 1 073 Mitroshkin, M. 686 673 537, 1 141 Mc Neilly, A. 114 Menzel, J. 412 Miu, P. McAhren, S. 449 Merezhanova, A. 1 165 Miura, K. Messa, P. 1 029 Miwa, K. 338 Miyamoto, Y. 949 Miyashita, K. 621 McCann, A. 779 McCormick, S. 112, 1 127 277 Messika-Zeitoun, D. 474 McCullough, P.A. McDaniels, K. 704 Messner, B. 477 Miyata, K. 537, 1 141 McGillicuddy, F. 534, 694 Metelskaya, V. Miyazawa, T. 886 Mchirgui, N. 1 111 629, 640, 663 Miyoshi, T. 586 McKendrick, J. 392 McKey, S. 1 031 McLoughlin, E. 719 McParland, J. 430 McWherter, C. 244 Md Yasin, M. 716, 965, 966 Meakin, P. 289 Medbury, H. 545 Mohd Kasim, N.A. Metso, J. Mezzano, D. 384, 623, 652 478 Miarka, P. 903, 912 Michael, L. 449 Michalis, L.K. 399 Michel, J.B. 474 Michell, D. 268 Mickiewicz, A. 956 Mlih, M. 283 Mo, F.E. 445 Mo, Z.C. 822, 823, 824 Muid, S. 441, 485, 923 Muinjonov, B. 597, 726, 787, 788, 831, 979, 1 025, 1 132 Mukhamedova, B. 1 222 Mukhamedova, M. 572 615 Mulder, M. 717 Montani, J.P. 479 Mullan, R. 650 Montecucco, F. 407 Müller, G. 403 Mora-Brugués, J. 384 Munakata, M. 899 Morales, C. 944 Mundal, L. 957 Morbini, M. 380, 391 Mundra, P. 314 Moregola, A. 458 1 158 Moreno, X. 1 056 MuñozHernández, R. Mori, K. 338 Muñoz, M. 434 Mori, M. 948 Muntean, C. 1 043 Mori, T.A. 471 Moriarty, P. 667, 910 Moriarty, P.M. 668 Moriconi, A. 865 Morihara, R. 583 Morlotti, B. 386 Morreale, P. 1 209 Morris, A. 95, 385 Morshed, S. 107, 1 028 Mortensen, M.B. 1 164 Morvan, M. 474 Mocan, M. 509 Moschen, A.R. 312 Moeton, M. 209 Moschetta, A. 205, 208 Mohd Ismail, A. 716 Mospan, M. 811 Mosteoru, S. 769, 1 046 Mostoslavsky, R. 127 Muntoni, S. 121 Murakami, K. 338 Murakami, M. 621 Muro, A.F. 554 Murphy, C. 980 Murrin, C. 1 031 Murtazaev, S. 1 204 Musayeva, Y. 1 025 Musikhina, N. 538, 557 Mussbacher, M. 448 Mut-Vitcu, G. 769 Muthuramu, I. 126, 655 Muxel, R. 241 Muzalevskaya, M.V. 718 Myhre, P. 1 102 Mysliwiec, M. 956 203 INDEX Nawawi, H. Nikolic, S. 870 Nurmuhammat, A. 1 090 Olkkonen, V. 111, 286, 495 P Nikolova, A. 791 Nussbaum, K. 127 Olset, H. 1 208 Paapstel, K. 1 129 Nilsen, R.M. 249 Nusshold, C. 499 Omote, Y. 583 Pacifico, A. 121 Nygård, O. 275, 779, 1 208 Omrane, M. 1 174 Pacioni, F. 1 097 Onda, A. 457 Packard, C. 49 Ongen, Z. 1 083 Packard, C.J. 1 081 Ooi, E.M. 394 Padilla-Mata, V. 1 230 Öörni, K. 47, 100, 204, 378 Padroni, M. 407 Parikova, A. 683 Parini, P. 47, 89, 203, 370, 1 027 Park, C.G. 120, 1 000, 1 185 Park, C.Y. 405, 737 Park, D.G. 512 Park, J.H. 738, 739, 1 004 502 Nilsson-Wolanin, O. 408 Nawrot, T. Nayeri, H. 721 Nilsson, J. 290 Nygård, O.K. 363, 367 Nazarenko, M. 520, 1 086 Nilsson, S.K. 88 Nyman, E. 596 Nechaeva, B. 1 165 Ning, T. 902 O NEDELCIUC, I. 575 Nishida, M. 63, 395, 653 O’Reilly, M. 534, 694 Pagano, M. 1 169 693, 1 049 Obendorf, F. 1 147 opan, S. 826 405, 737 369, 988 Nishida, T. Park, J.Y. Neely, D. Pagava, Z. 1 219 Oberkersch, R.E. 416 Opie, L. 710 404, 564 690 561 Park, K.C. Negi, P. Nishiuchi, J. Pagel, P. 90 711 Oppitz-Plörer, C. 21 Paiva, A. 827 Opris, S. 705, 802 Park, K.S. 564 913, 992, 1 176 ObregonGonzalez, A. 1 230 Negrean, V. 567, 570, 571, 572, 1 018, 1 036 404, 564 Nègre-Salvayre, A. Nizomov, A. Park, K.H. Obrowsky, S. 335, 622 Pajukanta, P. 241 363, 367 992 594 Njølstad, P.R. Orășan, O. Park, M. Odegova, A. 746 Palesano, O. 954, 1 169 1 029 541, 720 420 Noale, M. Oravec, S. Park, S.H. Ogawa, K. 1 021 Palmen, J. 238 645, 648 630 1 001 Nobécourt, E. Ordóñez Llanos, J. Park, Y.W. Ogundipe, T. 514 Palmisano, S. 671, 749 645 Noels, H. 291 Ordóñez-Llanos, J. 876 Parnet, P. Ogura, M. Palo, S. 706 Palomar Muñoz, C. 614 Parolini, C. Noguchi, H. 456 Oguz, S.H. 715 Nohara, A. 948 Oh, D.J. 522 120, 1 000, 1 185 131, 372, 511, 639, 689, 1 118 Nolasco, P. 532, 632, 633, 1 066, 1 073, 1 074, 1 075, 1 076, 1 077 818 551 Orekhov, A. Parodi, O. Noeva, E. 344, 700, 949 Neimark, A. 204 441, 485, 486, 487, 681, 716, 923, 965, 966, 1 211 740 Nekaies, Y. 638 Nekrasova, T.V. 718 Nelson, J. 209 Nelson, J.K. 664 Nemeckova, I. 480, 494 Neroev, V. 606 Neskudla, T. 871 Nestel, P. 314, 658 Nestvold, T. 864 Netea, M. 106, 270 Neville, M. 89 Nezafati, P. 1 197 Nezami, N. 817 Nezic, D. 821 Ngo Sock, E.T. 643 Nguyen, S.D. 204, 378 Ni, C.W. 482 Palominos, M. 478 Palotie, A. 241 PALTINEANU, B. 539, 628 Parra, E.S. 983 420, 444 Orekhova, V. 1 076, 1 077 Panagiotakos, D. 762, 846 Parvu, M. 775 Nolte, I.M. 413 Oh, G.T. Nony, S. 625 Oh, P. 392 Orera-Peña, M.L. 866 Panahi, Y. 918, 1 108 Pashos, E. 430 431, 554 Oh, P.C. 1 130 Orgera, G. 550 Panchal, A. 667 Pasqualini, L. 865 222, 301, 458, 616, 1063 Ohama, T. 395, 653 Orhan, B. 833 Panderi, A. 1 088 Passarelli, M. Ohguro, T. 561 Orlov, P. 929, 940 Panetta, D. 818 531, 698, 1 122 Ohmori, R. 537, 1 141 Oscar, C. 1 162 Pang, J. 1 030 949 957 355, 471, 1 168 Pasterk, L. Ose, L. Pasterkamp, G. 311 Ohta, T. 390 Osipova, I. 557 Pannier, B. 1 196 Patankar, J.V. 622 Ohta, Y. 583 Osokina, A. 551 Panov, D. 795 Patel, M. 104 390 Ossoli, A. 650 Panteleeva, A. 740, 890 Patel, S. 1 120 461, 886 Oster, D. 492 Pantoura, M. 617, 618 Patel, V. 545 1 029 Patsch, S.M. 1 079 Norata, D.G. Norata, G.D. Nordestgaard, B. Nordestgaard, B.G. 75, 211, 227, 237, 254, 429, 669, 1 080 123, 427, 1 164 Ohta, N. Ohtake, A. Oikawa, S. 63, 390, 395, 653 Osto, E. 719 Panzavolta, C. Ostolaza, H. 637, 1 056 Panzoldo, N.B. 983 Patsch, W. 662, 1 079 Okazaki, M. 653 Ottino, J. 938 Paone, S. 489 Pattison, J. 455 Okruhlicova, L. 565, 1 015, 1 121 Otto, M.E. 1 178 1 115 PATURET, A. 292 Oueslati, I. 858, 859, 867, 909 Papadopoulou Pozatzidou, D. Paul, J.L. 691 Papadopoulou, A. 1 092 Paulweber, B. 68, 272, 411, 503, 662, 1 079 Paulweber, M. 503 Pauwels, B. 856 Pavanello, C. 121, 386, 963, 1 058 Pavão, M.L. 1 155 Pavlaki, M. 657 425 Pavlouskova, J. 973 394 PAYZIN, S. 951 NICA, A.S. 574 Nordrehaug, J.E. 1 208 Nicholls, S. 61 Norioka, N. 1 041 Nicoletti, A. 474 Noto, D. Niculescu, L.S. 701, 1 082 121, 954, 1 169 Nielen, T. 270 Notsu, Y. 703, 1 135 Nielsen, S. 369 Novakova, D. 724 Okutan, H. 984 Nieves, J. 553 Novakovic, R. 821 Okuyan, E. 777 Ouguerram, K. 648 Papadopoulou, S.L. 399 Nikiforov, N. 532 Novikova, A. 568 Oldoni, F. 331 Ouweneel, A.B. 1 040 Papavasiliou, K. 1 092 Nikitin, A. 868 Novikova, L. 454 Oleynikov, V. Ovsyannikova, A. 832 Para, I. 992, 1 176 Nikitin, A.G. 1 048 Novitskaya, A. 573 Paragh, G. Nikitin, Y. 768 1 209, 1 210 Ozan Tiryakioglu, N. 1 083 Novo, G. 589, 590, 591, 603, 1 044 1 156 Nikitina, N. 1 066, 1 074, 1 075 Novo, S. Oliveira, G. Ozcebe, O. 984 Oliveira, H. 827 Ozerova, I. Novoa, J.M. 494 1 196 548, 555 843, 1 061 Parati, G. Nikitskaya, E. Oliveira, M. 629, 640, 663 435, 467, 612, 702, 1 151, 1 153, 1 227 Nikkola, E. 241 Ntallas, I. 1 035 Olivieri, O. 626, 656 Ozmen, F. 294 Pardina, E. 740 Nugraha, F. 576 421, 661, 877 Ozsvar-Kozma, M. 307 Parhofer, K.G. Nikolaev, M. Oliyarnyk, O. 819, 1 209, 1 210 Okada, T. 205 INDEX Pchelin, I. 842 Pchelina, S. 740, 890 Pedersen, E.K. 1 208 Pedersen, E.R. 363, 367 Pedrelli, M. 47, 203 Pedretti, R. 1 179 Pedro-Botet, J. 766, 1 012 Pedro-Botet, J.C. 975 888, 1 099, 1 109 Pingitore, P. 1 055 Polyakova, E. 1 149 Pinthus, J. 1 173 Polyakova, V. 510 Proietta, M. 544, 549, 550 Perez, C. 888, 904, 1 099, 1 109 Pinto, F. 1 198 Pompilio, G. 450 Peric, M. 821 Pinto, P.R. 698 Ponde, C. 1 062 Perier, M.C. 1 196 Pintus, P. 121 Pongratz, T. 541 Perin, M.A. 781 Piotrkowicz, J. 1 071, 1 084 Poon, I. 489 Perkmann, T. 307 PIRAQUIVE AGUDELO, J. 292 Pop, C. 862 Perrea, D. 382, 1 119 Pop, L. Pirazzi, C. 1 055 Perrotta, S. 549, 550 Pirhonen, J. 286, 915 Persègol, L. 711 Pirildar, S. 984 Ragino, Y. 644, 832, 929, 940, 964, 1 212 PrzepiorkowskaHoyer, B. 903 Pu, J. 83 Rahimian, R. 508 Rahman, T. Puhm, F. 1 131 441, 485, 486, 487, 681, 716, 820, 965, 966, 1 211 Pujato, M. 94 862 Pulakazhi Venu, V.K. 554 Popeijus, H. 340 Pulatov, U. 851, 861 Popeijus, H.E. 103 Rahmat, R. 441, 923 Rainer, S. Pulikal, A. 335 815 Rajani, R. 1 062 Pego, M. 592 Peinado-Onsurbe, J. 425 290 1 082 871 Persson, A. Popescu, A.C. Pelikanova, T. PIrisi, M. 599 Purnomowati, A. 576 821 1 063 545 805 Pellegatta, F. Pertsoulis, N. Popescu, H. Rajkovic, J. Pischon, T. 412 Pussinen, P.J. 410 1 025 Pellegrin, M. 1 019 529 1 082 Rakhimbayeva, G. Perveen, I. Popescu, R.M. Pistrosch, F. 403 Puzdriak, P. 728, 783 752 697 888 947 Pellegrini, N. Pery, T. Popova, A.B. Rakhimov, R. Piťha, J. Puzyrev, V. Popovic, D. 1 095 1 222 Pello, E. 768 121 520, 1 070, 1 086 Rakhimova, R. Pes, G. 515, 683, 1 068, 871 871 906 712 Pithova, P. Pyanikin, S. 818, 825 1 147 247, 463 Pelosi, G. Pesau, G. Pordy, R. Ramakrishnan, L. 762, 846 501 934 Pitsavos, C. Pyatchenkov, M. 946 538, 557 1 105 Peloso, G. Petelina, T. Porrini, M. Ramaswami, U. Plana, N. 906, 911 356, 528 Pylaeva, E. 551, 679 965, 966 273, 402 Posadas-Romero, C. Ramli, A.S. Peter, K. Peters, A. 313, 411 1 200 1 118 963 Pyoung Chun, O. Ramsvik, M.S. Penco, S. 358, 393, 766, 921, 944, 975 Pyatkova, I. 539, 540, 574, 628 1 054 1 127 312 Peter, J. Porteous, C. Ramirez, C.M. 356, 528 Petersen, C.M. 332 1 201 626 341 Pyung Chun, O. Ranzato, E. Peng, H. Posadas-Sánchez, R. 822, 823, 824 Peterson, K.L. 455 Postnov, A. Ras, R. 1 104 Petrek, M. 1 005 655, 1 076, 1 077 658 617, 618 Peng, X.S. Pyush, M. Raptis, N. Rasente, Y. 416 Petrides, F. 119 Pláteník, J. 517, 558 Potekhina, A. Raslova, K. 1 052 Petriello, M. 385, 1 093 Pleava, R. 769, 1 046 Rather, R. 722 Petrini, J. 521 Plebani, M. Rathmann, W. 411 Petrkova, J. 1 005 Rathouska, J. 494 petrulioniene, Z. Rato, Q. 993 Raut, M. 659 PENA, C. Penning-van Beest, F. 760 Peralta, J. 449 Pereira-Flores, K. 478 Pereira, A. 943, 945, 981, 1 166, 1 167 Plat, J. 103, 340, 704, 1 096, 1 100, 1 103, 1 104 Q 551, 679 Qin, J. 524 Potočková, J. 517, 558 Quartuccio, S. 588 1 029 Potočnjak, I. 707 Que, X. 455 Plevin, R. 498 Pouwer, M. 245, 446 1 099 784 Plösch, T. 804 Povlsen, G.K. 513 Quezada-Feijoo, M. 784 Pocovi, M. 358 Pozzi, C. 898 1 156 petrylaite, M. Quinaglia e Silva, J.C. Pereira, J. 478 Pettersson, K. 690 Podesser, B.K. 789 Prabhakaran, D. 767 Quintao, E. 1 122 Ray, K. 61 Pérez Cuellar, M. 630 Pfaffenberger, S. 541 Podpalov, V. 581 PRADA, G. 540, 574 Quintao, E.C.R. 698 Ray, K.K. 253 Perez Guerrero, P. 615 Pfeiffer, L. 313 Poelz, W. 882 PRADA, S. 540, 574 Quitterer, U. 1 024 Raz, O. 563 Perez Isla, L. 945 Phillips, H. 942 Pogorelova, O. 551, 679 Prager, M. 720 Qureshi, A.R. 47 Razny, U. 546, 1 016 Perez Ternero, C. 381, 1 125 Piacentini, L. 1 034 Poirier, S. 98 Pramfalk, C. 89, 1 027 R Razvodovsky, Y. 1 213, 1 214 Piantadosi, C. 1 183 Pojskic, B. 706 Prasongsukarn, K. 569 Raal, F. 465 Real, J.T. 358 Piccinocchi, G. 924, 925 Pojskic, L. 706 Prassl, R. Raal, F.J. 976 Reaven, P.D. 45, 117 Pichler, M. 1 146 Pokrovskiy, A. 1 023 199, 894, 1 142, 1 143 Reblova, K. 973 692 Pokrovsky, A. 793, 906, 911 767 269, 483 Piemontese, A. Praveen, P.A. Rabelink, T.J. Rebnord, E.W. 363 396 Pokrovsky, S. 707 781, 920 Reda, A. 797 316, 318, 325 Pregartner, G. Rached, F. Piepoli, M. 679, 685, 686, 687 421, 877 946 Pieper, L. Pravenec, M. RABES, J.P. Prehn, C. 290 Reddy, K.S. 767 446 535, 562, 1 068 430 Pieterman, E. Poledne, R. Rader, D. Previato, L. 1 029 Radovic, B. 284, 443 Redezuk, G. 983 Poli, A. 692 Princen, H. 446 Radulian, G. 805 Redmond, E. 476 Radulović, B. 707 Redpath, G. 112 Radulović, S. 499 Rega-Kaun, G. 720 Radwan, M. 82 Regmi, P. 659 Raggi, P. 714 Reiber, J.H.C. 399 Reim, S. 128 Perez-Calahorra, S. 115, 358, 765, 766, 921, 975 206 Perez, A. Perez-Calvo, J. 505 Pérez-Hernández, N. 528 Pérez-Hernánez, N. 356 Perez-Marques, F. 667 Pieterman, E.J. 245 Pérez-Méndez, O. 713 Pietrzycka, A. 903 Pérez-Pérez, A. 876 Pihlajaniemi, T. 915 Perez-Ruiz, M.R. 971 Piir, A. 1 129 Perez-Serra, A. 1 162 Piña-Aguilar, R. 1 054 Ping-Yan, C. 902 Polis, A. 389 Princen, H.M.G. 245 Polizzi, G. 819 Prins, J. 269 Polonskaja, Y. 1 212 Prof. Dr. Dukat, A. 1 145 Prof. Dr. Oravec, S. 1 145 Polus, A. 546 207 INDEX Rein, P. 366, 731, 732, 733, 839, 883, 991, 1 067, 1 136, 1 137, 1 138 Rioja, J. 428 Rosa, I. 1 162 Ryzhkova, A. Ripatti, S. 111, 235, 236 Rosa, R. 796, 1 008 S Risérus, U. 1 116 Rosendaal, F. 113 Sabanovic, S. Reis de Azevedo Rabello, F. 863 Reis, A. 1 069 Reischl, E. 313 Reiz, B. Salyamova, L. 591, 603, 1 044 Sardo, M.A. 496, 506, 675, 1 050 967 Salzmann, K. 503 Sarecka-Hujar, B. 1 218 448 Sarrafzadegan, N. 806, 1 197 Riško, P. 517, 558 Rosendaal, F.R. 293 Saburova, O. 473, 853 Salzmann, M. Riso, P. 1 105 Rosenson, R.S. 392 Sachdev, V. 622 Samani, N.J. 240 Sarzani, R. 1 161 Ristic, T. 1 217 Rosłoniec, E. 584, 585 Sadeghi, M. 806, 1 197 Samoka, A. 587, 790 Sasaki, J. 461 Samperiz-Legarre, P. 505 Sasaki, M. 693, 1 049 Sasiela, W. 247 Sampietro, T. 976 Sasiela, W.J. 246 Sanak, M. 1 016 Sassolas, A. 625 Sanchez Lopez, Y. 959 Satoh, N. 620 Sánchez MuñozTorrero, J.F. 1 216, 1 215 Satta, N. 407 Sánchez Quesada, J.L. 630 Sattar, N. 1 013 Sausen, G. 93 Savolainen, M. 378 Savopoulos, C. 736, 794 Savostyanov, K. 785 Sawamura, T. 636 Sawant, R. 1 062 Sayfutdinov, R. 613, 848 Sazonova, M. 532, 1 066, 1 074, 1 075, 1 076 Scarinzi, P. 725 Schaefer, A.K. 789 Schaeffer, C. 283 Schalij, M. 578 Schaltenberg, N. 48 Scharfmann, R. 645 Scharin Täng, M. 647 Scharnagel, H. 396 Scharnagl, H. 374, 409, 624, 1 146 Schartum-Hansen, H. 367, 1 208 Schatz, U. 682 Schauer, S. 284 Scheicher, B. 622 Scheideler, M. 894 Scheja, L. 88, 108 Schernthaner, G.H. 507, 771, 772, 1 147 Schiavetto, E. 1 097 Schiffmann, R. 277 Schilcher, I. 374, 499 Schlager, S. 284, 443 Schlein, C. 88 Schmid, J.A. 448 Schmidinger, B. 649 109, 340, 1 103 Rosqvist, F. 1 116 Sädevirta, S. 915 Ross, J. 1 009 Saely, C. Rivas, A. 630 240 Rossell, J. 425 Rivellese, A. 1 183 Religa, P. 800 Rossetti, L. Rizzo, B. 1 022 1 033, 1 034, 1 039 Ren, K. 822, 823, 824 Rizzo, P. 1 022 Rossi, N. 996 366, 731, 732, 733, 839, 879, 883, 991, 1 067, 1 136, 1 137, 1 138 Robier, C. 1 142 Rossini, M. 1 029 Saemann, M.D. 699 Robinson, J.G. 246, 463 Rosticci, M. 380, 391, 749 358 Robinson, T. 1 133 Roth, A. 407 Sáenz-Aranzubía, P. Rocchiccioli, S. 818, 825 Roth, E.M. 463 Saez, C.G. 478 Roche, H. 694 Rothe, M. 285 Safarova, M. 686 Rocio, T. 888 Rotllan, N. 312 Sag, S. 984 Roda, A. 1 022 Rovati, G. 1 017 Sagitov, I. 745 Roden, M. 411 Roversi, G. 407 Saheb, S. Rodriguez -Rosety, 888 M. Roy, A. 712, 767 Sahebkar, A. Rubio-Gracia, J. 505 Rodríguez Cubero, A. 835, 836, 837 Rudling, M. 336, 376, 1 116 Rodríguez-de Miguel, M. 866 Rodriguez-Leal, C. 888, 904, 1 099, 1 109 Rencova, E. 1 026 Renker, M. 274 Rensen, P. 90, 111, 113, 556 Rensen, P.C.N. 210, 293 Rensen, S. 113 Rentz, T. 827 Ress, C. 503 Ressia, A. 961 Retterstøl, K. 957, 1 055 Revnic, C.R. 539, 540, 574, 628 REVNIC, F. Reyes, X. Rha, S.W. 208 1 074, 1 075 539, 540, 574, 628 945, 961 Ritsch, A. 120, 1 000, 1 185 Rodríguez-Pérez, J.M. 356, 528 Rhainds, D. 696 904 Rhéaume, E. 696 Rodriguez-Rosety, M. Rhee, K.S. 493 106, 121, 717 Riascos-Bernal, D. 94 Roeters van Lennep, J. Ricci, . 337 Rogers, M. Ricci, C. 419 Roglans, N. Ricci, M. 1 161 Ricci, M.A. Rus, V. 536 42 Ruscica, M. 337, 386, 431 508, 1 123 Russo, I. 276 Rohrer, L. 345 Russo, R. 1 209 849, 865 Rolando, B. 491 Rusu, E. 805 Richart, A. 223 Romano, D. Rusu, F. 805 Rico Martin, S. 1 215, 1 216 Rutten, J. 270 Riesmeyer, J. 61 Ruuth, M. 378 Riga, M. 794 Rvatcheva, A. 542 Riksen, N. 106, 270, 556 Ryan, R.O. 87, 288 Riksen, N.P. 669 Ryazankina, N. 1 047 Ring-Dimitriou, S. 662 Ring, M. 521 Roncales-Garcia Blanco, F. 505 Rye, K.A. 104, 119, 342, 704 Ringdal Pedersen, E. 275 Ronda, N. 697, 715 Rinnerthaler, M. 662 Ros, E. 975 434 Romijn, F. 578 Sahlin, S. 1 027 Sanda, G.M. Sairyo, M. 395, 653 488, 523, 701, 1 082 537, 1 141 Sandhu, M.S. 680 496, 506, 588, 675, 1 050 Sang Ho, J. 1 200 Sang Hong, B. 1 200 Sang-Don, P. 1 130 1 109, 904, 1 099 536 Romeu, M. 384, 876 Ruiz-Estevez, B. Rus, H. 938 Sánchez-Quesada, J.L. Saitta, A. 61 Romero, E. 672, 918, 1 108 531 Ruotolo, G. 1 055 1 109 244 Sanchez-Orellana, E. 503 630 Romeo, S. 505 Rui, L. Rull, A. 589, 590 Sanchez-Marteles, M. Rufinatscha, K. 505 Romanovskaya, E. 975, 358, 921 Saita, E. Ruiz-Laiglesia, F. 1 188, 1 189, 1 190 SánchezHernández, R.M. Sakata, Y. 63, 395, 653 Sangüesa, G. 508, 1 123 Sakellarios, A. 399, 818 Sanjana, N. 262, 352 Sakly, M. 638 Sant’Anna Melo, E. 863 Sakri, F.H. 716 Santer, D. 789 Saksi, J. 354 Santer, P. 312 Sakurada, M. 1 049 Santilli, F. 1 033 Sala, A. 1 017 Salakhitdinov, S. 567 Santoro dos Santos 863 Pereira, S. Salashenko, A. 1 042 Santos Filho, R. Salatzki, J. 285 Salcioglu, O. 984 Saleh, Y. 587, 790 Salem, M. 1 171, 1 172 Salerno, A. 827 Salim, V. 677 Salinas, M. 93 SALMAN, N. 951 410 818 Rymar, O. 832 Salomaa, V. Rynkiewicz, A. 956 Salvadori, P.A. Ryu, J.K. 1 001 Salvayre, R. 711 981, 1 166, 1 167 Santos, D. 384 Santos, E. 1 155 Santos, F. 843 Santos, M. 592 Santos, R. 920, 945, 976 Sanz-Bescos, C. 505 Sapozhnikova, I. 878 Saraiva, C. 843 Sarantopoulos, A. 617, 618 209 INDEX Schmidt, B. 396 Schmidt, N. 396, 937 Schmitz, C. 291 Schmölz, L. 383 Sergienko, I.V. 947 Schneider, M. 278, 772 Serrano Jr, C.V. 781 Schneider, W. 241 Serruys, P.W. SERUSCLAT, A. Schneider, W.J. 133, 649 Schnitzler, J. 81 Schoepf, U.J. 274 Schofield, J.D. 426 Scholler, E. 283 Seung Hwan, H. Seung Woon, R. 435, 467, 612, 702, 1 151, 1 153, 1 227 Shimizu, M. 579, 610, 727, 755, 756, 905 1 223 Stanikova, D. 1 052 Simonova, Z. 776 Somaratne, R. 462, 1 205 Stanisz, A. Simonyi, G. 1 007 Somerville, R. 1 031 796, 840, 841 491 Sommariva, E. 450 Stankovic, A. 373 543 292 Shiomi, M. 1 021 Singh, A. 712 Somodi, S. 1 151, 1 153 693, 1 049 Singh, N. 655 Song, H.C. 439 Staudacher, G. 503 930 Singh, S. 712 Song, K.H. 884 Stauffer, F. 1 177 666 Sinisalo, J. 378 Soon Yong, S. 1 130 Stavek, P. 515, 871 Shiqun, C. 902 Sinke, R. 331 Sopic, M. 122 Stavri, S. 1 085 Shiri-Sverdlov, R. 113 Sinyov, V. 426, 462, 976 Stef, M. 358 Stefan K., N. 48 1 130 1 200 Seyedikhosroshahi, 611 S.A. Shiotani, K. Shipman, K. Shipman, K.E. Shishkin, A. 842 412 Shakhtshneider, E. 644, 832, 929, 940, 964 Shiue, L. 269 Shkurat, T. 1 074 Shalaby, A. 797 Shlomin, V. 783 Shalaeva, A. 744 Shlyachto, E. 1 149 Shalaeva, E. 752, 851, 861 Shogenova, M. 454, 526, 542 Shokouhi, B. 817 Shpektor, A. 548, 555, 1 047 Schwarzova, L. 939, 962 Shaligram, S. 508 Scopece, A. 450 Shalimova, A. 869 Scotti, I. 616 Shamkhalova, M. Scrimali, C. 954 860, 868, 900 500, 598, 602 Soltani, N. Starodubtseva, I. Schulze, M.B. Scrylev, S. 1 105 Sinelli, M. 1 144 368, 438, 1 098 1 052 Simonetti, P. 621 681 378 415 Stanik, J. Shinohata, R. Shahrawat, R. Schwab, U. Stangl, H. 582 399 Shaari, S.A. 619 546, 1 016 Solovieva, E. 350, 371, 1 078 945, 995 33, 240 Solnica, B. 650 Shin, S. 894 Schutte, A.E. 754 Simonelli, S. 1 002 Schreier, L. Schunkert, H. Simon, A. Shimizu, R. Schratter, G. Schwandt, P. 210 Seres, I. Shamkhalova, M.S. 1 048 Shapira, C. 932 Sedova, E. 510 Shapira, I. 563 Segura, E. 888, 904, 1 099, 1 109 Shaposhnik, I. 1 042 Sharapov, N. 1 204 Segurado, R. 1 031 Sharashidze, N. 1 219 Sehar, N. 667, 910 Sharifi, M. 952 Seifert, R. 367 SHARMA, M. 112 Sekerkova, A. 562 Sharma, S. 815, 816 Seleem, M. 587, 790 Sharma, V. 880, 1 144 Selice, R. 725 Sharpe, L. 209 Selimovic, H. 706 Shchinova, A. 551, 679 Seljeflot, I. 1 102 Shchipakin, V. 500 Sella, S. 1 029 Shehab, A. 1 181, 1 182 Semenkin, A. 1 165 Shehu, J. 1 022 Semenova, E. 998 Shelkov, G. 400 Semenova, I. 740, 890 Shelley, E. 980 Seo, H.S. 120, 1 000, 1 185 Sheng, Q. 268 Sherbakova, E. 907 Seo, J.B. 512, 1 010 Shestakova, M. Sequeira Duarte, J. 843 860, 868, 900 Seraceni, S. 407 Shestakova, M.V. 1 048 Serban, M.C. 672 Shih, M.F. 1 126 1 066, 1 074, 1 075 Soran, H. Sirenko, O. 786 Sorin Nicu, B. 509 Stefanadis, C. 762, 846 Sirirat, R. 1 106 Soronen, J. 111 Stefanovic, A. 436 Sirojiddin, K. 1 221, 1 222 Sorrentino, V. 664 Stefánsdóttir, B.R. 1 220 Sironi, M. 222 Sorsa, T. 410 Stein, E.A. 465, 976 Sirtori, C. 121, 963 Soska, V. 950 Steinberg, A. 244 Sirtori, C.R. 131, 386, 639, 689 Sotnikova, R. 1 015 Soyal, S. 662 SteinhagenThiessen, E. 669, 935, 989, 1 087 Sisic, I. 706 Soyal, T. 294 Stender, S. 211 Skeldal, S. 332 Spang, J. 492 Stenvinkel, P. 47 1 031 Skilton, M. 758 Spannella, F. 1 161 Stepanov, A. 1 026 Shuto, T. 1 041 Škop, V. 421, 661, 895 Spanou, M. 794 Stern, C. 477 Shuto, Y. 886 Skoumas, I. 762, 846 122 Stevens, A. 426 Si, S. 695 Skroblin, P. 312 Spasojević Kalimanovska, V. Stewart, F. 650 Siahmansur, T. 426 Skryabin, N. 520, 1 086 436, 741, 874 Steyrer, E. 328 SIALVERA, T.E. 1 092 Sleptcov, A. 520, 1 086 SpasojevićKalimanovska, V. Stiefel, P. 1 158 Sibinga, N. 94 Smiianova, O. 1 187 Speidl, W. 541, 720 Stimjanin, E. 706 Siebel, A. 223 Smiianova, Y. 1 187 Sperlongano, S. 924, 925 Stitziel, N. 946 Siepi, D. 849 Smit, N. 578 Speziali, G. 656 Stivala, S. 127 Sifuentes Diaz, E. 614, 615 Smith, W. 619 Spina, R. 954, 1 169 Stöckl, D. 411 Sigurðardóttir, Y.R. 1 220 Smyth, S. 95 Spira, D. 935, 989 Stoekenbroek, R.M. 680 Sijbrands, E. 717 So, W.Y. 885 Spitz, C. 128, 305 Stoijkovic, S. 418 Silva, A.P. 1 178 Sobenin, I. Spolding, B. 1 113 Stojakovic, T. Silva, I.T. 814 Sposito, A. 1 156 374, 409, 624, 1 146 Silva, K.S. 698 532, 633, 1 066, 1 073, 1 074, 1 075, 1 076, 1 077 Stadiotti, I. 450 Stokic, E. 870, 1 095 Silva, R. 592 Sobotka, L. 1 112 Stadlbauer, V. 440 Stoll, M. 945, 961 Sima, A.V. 488, 523, 701, 1 082 Söderlund, S. 241 Staessen, J. 768 Stone, G.W. 399 Sodi, R. 1 081 Staffler, G. 245 Stosic, Z. 870, 1 095 Simental-Mendía, L.E. 672 Søfteland, E. 249 Ståhlman, M. 647 Stover, C. 916 566 Stramba-Badiale, M. 431 314 Sohrabi, B. 1 059 Simes, J. Stamatelopoulos, K. Simic-Ogrizovic, S. 436 Sokolov, A. 501 Stanciu, O. 609, 792 Strand, E. Simionescu, M. 523, 527, 701, 1 082, 1 085 Sol, W.M.P.J. 483 Stancu, C.S. 363, 367, 1 208 Soler, C. 944 488, 523, 701, 1 082 Straniero, S. 1 116 434 Stanek, V. 1 068 Straußfeld, E. 291 1 102 Stangl, G. 1 154 Stravinsky, J. 827 Shrivastava, A. Simionescu, N. 1 082 Soler, J. Simmelbauer, A. 102 Solheim, S. 211 INDEX Straznicky, N. Svobodova, M. 889, 892 Strelow Thurow, H. 972 Swartz, E. 93 Strijdom, H. 502, 514 Sweeney, M. 118 Stroes, E. 13, 77, 81, 106, 299, 464, 547, 714 Swiader, A. 822, 823, 824 Thedrez, A. 645 Theodorou, K. 704 Tankovskiy, V. 606 Thiersé, D. 283 346 Tantry, U.S. 417 Thiessen, E.S. 14, 668 Swier, V. 82 Tarasenko, N. 1 070 Torres-Courchoud, 505 I. Thomaidis, A. 657 277 244, 696 1 230 Swift, C. Tardif, J.C. Torres, L. Thomas, F. 1 196 93 Tardivel, S. 691 Thomaz, S. 1 177 ToseskaTrajkovska, K. 678 Swirski, F. Swirski, F.K. 306 Tarhbalouti, K. 1 157 Thompson, P. 314 1 159 770 Syed, A. 426 Tarlarini, C. 963 Thorand, B. 411 Tosheska Trajkovska, K. 956 Sysi-Aho, M. 275 Tarlovskaya, E. Thymiakou, E. 130 Toshev, B. Szentimrei, R. 435 746, 878, 1 110, 1 165, 1 191 Tibolla, G. 347, 431, 472 776 Ticha, A. Tartari, S. 222 Tichy, L. Tarzamni, M.K. 817 Tietge, U. Tas, S. 704 Stroes, E.S. 669 Stroes, E.S.G. 392, 627, 1 009 Strohmaier, S. StroniawskaWoźniak, M. 212 658 Szentpéteri, A. 435, 702, 1 151 Tang, Z.L. Toro, R. 614, 904, 1 099, 1 109, 1 162 Trzeciak, J. 584 Tsai, W.C. 516, 773, 919 Tscharre, M.L. 1 147 Tschöp, M. 298 Tselepis, A. 928, 1 035, 1 128 Tselios, K. 617, 618 Tselmin, S. 403, 682 Tseng, H.C. 533 572, 1 018 Tsiantoulas, D. 307 Toth, P. 389 Tsimihodimos, V. 432, 709 1 112 Tothova, V. 724 Tsimikas, S. 962, 973 Touqui, L. 704 47, 699 Tousoulis, D. 762 455, 627, 668, 669, 670, 673, 674, 680 Tietge, U.J.F. 804 Trabattoni, D. 1 033, 1 034 Tsoukatos, D. 1 035 84, 217 Tikka, A. 623 Tragante do Ó, V. 240 Tsoumani, M. 1 035, 1 128 111, 241, 387, 463 Tilg, H. 312, 503 Trakarnwijitr, I. 723, 1 206 Tsujita, M. 375 Timina, I. 906, 911 Tramontana, A. 1 154 Tsunoda, T. 1 021 Stryeck, S. 443 Stulnig, T. 231 Stumpf, C. 377 Sztanek, F. Su, C.H. 348 T Suarez-Tembra, M. 975 Ta, H. 273 Suchanek, P. 515 Tabet, F. 119, 342 Suciu, L. 1 043 Taborsky, M. 1 005 Sudjana, P. 576 Tada, H. 948 Tatomir, A. 536 Timmerman, I. 481 Tran, H. 757 Tsyrulneva, N. 811 Sugihara, H. 886 Tae Hyun, Y. 1 200 Tauchi-Brück, M. 377 Tinoco Racero, I. 615 Trapani, G. 588 Tubeuf, E. 104 Suh, J.W. 1 032 Tae-Hoon, K. 1 130 Tauchi, M. 1 069 Tinoco-Racero, I. Trautwein, E. 1 104 Tuckwell, K. 1 013 Suhre, K. 297 Taehoon, A. 1 130 Taurino, M. Trautwein, E.A. 1 092 Tudorache, I.F. 527, 1 085 Sukhova, G. 93 Taghipour, H. 1 108 544, 549, 550 888, 1 099, 1 109 Tinoco, I. 904 Travnikova, E. 1 140 Tuimala, J. 354 Sukmanova, I. 1 224, 1 225, 1 226 Taherkhanchi, B. 566 Tavares Bello, C. 843 Tiran, B. 707 Trayhurn, P. 849 Tuomi, T.M. 354 Takahashi, A. 949 Tavintharan, S. 994 Tishko, V. 501 Trbušić, M. 707 Turer Cabbar, A. 1 150 Sullivan, D. 314 Takemoto, Y. 1 041 Tawakol, A. 78, 80 Titze, J.M. 54, 55 Tregubov, A.V. 718 turhan caglar, F.N. 826 Sullivan, D.R. 471 Takiguchi, S. 693 TBA, 320, 433 Titze, S. 278 Tremblay, K. Turnbull, A.V. 622 Sulowicz, W. 903 Talbi, E. 1 111, 1 174 Tegla, C.A. 536 Tixeira, R. 489 353, 660, 1 053 621 Talbot, C. 340, 1 103 Tejedor, M.T. 971 Toell, T. 1 229 Sun, J. 248 Tallada Iborra, R. 531 Tell, G. 275 Toh, R. 338 222, 530, 1 033, 1 034, 1 039 995 Sumino, H. Tremoli, E. Tuseddo, J.C. Tybjærg-Hansen, A. 237, 211, 427, 429, 1 080 Sun, W. 677 Tallgren, T. 690 Tell, G.S. 363, 367 Tokgözoglu, L. 407 Tzakos, A. 1 128 516 Talmud, P.J. 238 Tellis, C. 928 Trescher, K. 789 Tzani, A. 382, 1 119 Sundbom, M. 1 116 Talukdar, S. 88 Temizhan, A. 984 72, 255, 294, 296, 715, 984 Trentini, A. Sun, Y.T. 1 152 Tziakas, D. 657 Sung Ho, H. 1 200 Tam, C. 885 Temporelli, P.L. 1 179 Tziomalos, K. Sung Woo, K. 1 130 Tam, L. 62 Teng, Z. 349 617, 618, 794, 1 088 Sung, H.R. 564 Tamanaha, T. 949 Teodoro, W. 1 122 Sunkara, M. 385 Tamás, F. 1 007 Teoh, Y.P. 936, 990 1 227 Tarlovskaya, Y. Taskinen, M. Taskinen, M.R. Suo, R. 823 Tamborino, C. 407 Teplov, A. 906 Suoniemi, M. 639 Tami, J. 669, 670 Terrand, J. 283 Susekov, A. 582 Tamura, S. 1 021 Terrin, M. 725 Suspitsyna, I. 1 225, 1 226 Tan Kurklu, T.S. 1 228 Tershakovec, A. 389 Sutcliffe, M. 349 Tanaka, N. 338 Tervahartiala, T. 410 Suwa, J. 875 Tanaka, Y. 579, 610, 727, 755, 756, 905 Tesloianu, D. 575 Suzuki, N. 537, 1 141 Svardal, A. 363, 1 208 Svetlikov, A. 400 Svingen, G.F.T. 363, 367, 1 208 Tanashyan, M. Tang, L. 500, 598, 602 465, 976 Tesmenitsky, Y. 93 Tetik Vardarli, A. 953 Thakkar, H. 712 Thaler, B. 418 Toledo, V. 1 122 Tretjakovs, P. Toma, L. 488, 701 Tribuntseva, L. 750 Tomas, L. 290 Trieb, M. 440 Tomashevskaya, Y. 1 044 Triebswetter, S. 908 Tomassini, J. 389 Trikash, I. 1 203 Tomescu, M. 1 043 Trikha, D. 722 Tomilova, D. 782 Trindade, L. 1 156 Tomlinson, B. 357, 885 Tripepi, G. 1 029 Tondo, C. 450 Tripoten, M. 551, 679 Toni, D. 544 Tritapepe, L. 549, 550 Tonkin, A. 314 Trivella, M.G. 818, 825 Tootsi, K. 1 129 Trnovska, J. 421, 661, 895 Tori, M.O. 1 021 Trojak, A. 912 Torii, H. 1 002 Trompet, S. 293 Trusca, V.G. 527, 1 085 U Uboldi, P. 554 Ueda, T. 1 045 Ueland, P. 779 Ueland, P.M. 367, 1 208 Ulbricht, C. 757 Ulianova, I. 860 Ulmer, H. 770 Umarov, A. 608 ungan, I. 826 Urazgildeeva, S. 400, 718 Usenko, T. 740, 890 Usui, S. 621 213 INDEX Utermann, G. 234 van Tuijl, J. 106 Vesa, S.C. 913 Utkina, E. 687 Van Veldhoven, P. 655 Vianello, D. 725, 987 Uto-Kondo, H. 693, 700, 1 049 van Vlijmen, B.J.M. 1 040 Uusitupa, M. 378 V Vickers, K. 268 van Zonneveld, A.J. 269, 483 Vihervaara, T. 275, 378 Vandendaele, L. 856 Viklicky, O. 683 Vanoli, D. 595, 596 Vikulova, O. 868, 900 Vrablík, M. 366, 731, 732, 733, 839, 879, 883, 991, 1 067, 1 136, 1 137, 1 138 Watts, G.F. 394, 471, 672, 926, 927, 1 168 Witztum, J.L. 455, 627, 668, 669, 670, 673, 680 Weber-Boyvat, M. 286 Weber, C. 128, 305 Wohlfahrt, P. 515 Weber, J. 127 Woitas, R. 243, 962, 778 1 146 502 Wojciechowska, W. 931 641, 651 Wojdan, K. 518, 801, 828 418, 541, 720 Vagida, M. 1 047 Varava, A. 911 Vikulova, O.K. 1 048 Vrieling, F. 556 Webster, I. Valdivielso, J.M. 774 Varbo, A. 123 Vila Belmonte, A. 766, 975 Vriz, O. 599 Weers, P. Valdivielso, P. 766 VARDARLI, A.T. 951 Vila, À. 944 Vuilleumier, N. 364, 407 Wegscheider, M. 443 Wojta, J. Vila, L. 944, 1 012 Vujic, N. 284, 335 224, 470 480, 494 481 Wolf, D. Varejckova, M. Weijers, E.M. Vilela-Martin, J. 1 178 Vynnychenko, L. 1 187 314, 362 435, 1 151 649 Wong, G. Varga, E.V. Weijler, A. Viljoen, K. 1 031 Vyzantiadis, T.A. 1 088 994 467, 612, 702 412 Wong, M.S. Varga, V.E. Weikert, C. W 362, 449 Wong, N. 118 835, 836, 837 Weir, J. 769 Valenti, L. 1 055 Valenti, V. 954, 1 169 Valikulova, F. 1 231 Valkov, I. 917 Vargas-Alarcón, G. 356, 528 Vallejo-Vaz, A.J. 1 158 Variya, B. 1 120 Villanueva Fernández, E. Varol, S. 777 Villar, J. Varret, M. 946 Villarreal-Molina, T. 356, 528 Vasconcelos, C. 843 Vinaixa, M. Vasilieva, E. 548, 555, 1 047 Vincent, V. Vinchi, F. 102 842 Vindis, C. 346 van Beek, L. 556 van Bockxmeer, F.M. 471 van Buul, J.D. 481 van Capelleveen, J. 286, 331, 627 van Dam, A. 556 van de Pavert, S.A. 481 Vasilkova, V. 852 Van de Voorde, J. 856 Vaslin-Reimann, S. 634 van den Berg, B.M. 483 Vassalo, T. van den Berg, S. 556 Vasudevan, A. van den Hoek, A. 446 Vatrano, M. van den Munckhof, 270 I. van der Burgt, Y. 578 van der Hoorn, J.W.A. 245 van der Krieken, S.E. 103 van der Laarse, A. 578 van der Tuin, S. 113 van der Valk, F.M. 214 Vonbank, A. 669 van der Veer, E. 269 van der Veer, E.P. 483 van der Vorst, E. 704 Van Eck, M. 704, 1 040 van Esch, H. 269 Van Gaal, L. 215, 719 van Gils, J. 269 van Gils, J.M. 483 van Harmelen, V. 556 van Kooten, C. 269 van Leuven, S.I. 547 van Rooyen, J.M. 619 van Tits, L.J. 127 Vasilkova, O. Viney, N.J. 1 158 434 712 668, 669, 670 62 Welsh, P. 1 013 Wood, D. 872 Wen, J.T. 1 014 Woong Chol, K. 1 130 Wahl, S. 313 Werner, C. 381, 624 Worm, J. 513 Wakefield, D. 107 Werngren, O. 203 Worsfold, B.P. 743 313 Werstuck, G. 1 173 Worth, G. 1 009 Walder, K. 1 113 Werz, O. 383 Worthmann, A. 48 Waldmann, E. 394 West, H. 758 Worthy, G. 1 009 383 Westcott, C. 502, 514 Woudberg, N. 710 903, 912, 931 Whittaker, A. 273 Wu, Y. 704 Wick, G. 351 Wühle-Demuth, M. 1 087 Widhalm, K. 960, 1 107 X Wade-Martins, R. Wadsack, C. Waldenberger, M. Wallert, M. Walus-Miarka, M. 742, 941 Virzi, J. 407 Visek, J. 1 112 Wan Ahmad, W.N.H. 716 277 588 Vishnolia, K. 1 157 Wan, J. 873 Więcek, M. 585 Xenaki, C. 1 115 849 Visinoni, C. 898 Wang, A. 248 903 Xia, S. 669, 670 Vaverkova, H. 635, 962 Visocka, A. 1 152 Wang, C.C. 704 WieczorekSurdacka, E. Xiao, J. 1 186 Vaysberg, A. 1 231 Vitale, G. 1 209 Wang, F. 447, 873 Wieffer, H.M. 392 Xida, L. 490 Vitali, C. 386 Wang, H.J. 810 Wiegman, A. 968 Xilifu, D. 1 090 Vitverova, B. 480, 494 Wang, J.M. 105 Wigren, M. 290 Xiong, S.L. 823 Wiklund, O. 136, 225, 251, 1 055 Xu, Y. 695 312, 411, 1 229 Yadav, R. 426 Yadernaya, A. 568, 728, 850, 1 163 Vaudo, G. Vazquez Cardenas, 959 A. VazquezAlfageme, J. 1 162 Vivanco, F. 129 Wang, K.Y. 456 Vlachos, I. 382, 1 119 Wang, L. 339 Vecera, R. Vedie, B. 421 Vlad, A. 1 082 Wang, P. 447, 873 691 Vladimirov, S. 741, 874 Wang, Q. 447 Veierød, M.B. 957 Willeit, K. 503, 1 229 Vlaicu, S.I. 536 Wang, X. 402, 695 Vekić, J. 436, 741, 874 Willeit, P. 312 Voevoda, M. 644, 795, 832, 929, 940, 964, 1 212 Wang, Y. 113, 210 Yagi, K. 948 293 Wanner, C. 699, 1 192 Willems van Dijk, J.A.P. Yahya, R. 717 Wanschel, A. 827 Willems van Dijk, K. 113, 210 Yakushiji, E. 693 947 680 Willenborg, C. 240 593 Voevoda, M.I. Wareham, N.J. Yamada, K. 970 627 William, K. 248 456 Vogt, A. Wareham, N.T. Yamada, S. 1 043 956 Williams, H. 545 948 Voicu, M. Wasag, B. Yamagishi, M. Voidazan, S. 775 Wasiak, S. 118 Wilson, A. 723, 1 206 Yamashita, S. 63, 395, 461, 653 VOINEA, S. 539, 628 Wasserman, S.M. 976 Wilson, R. 313 Yamashita, T. 583 Volpe, R. 1 097 Waters, D. 119 Winkels, H. 128, 305 Yamazaki, Y. 1 041 Volpi, N. 416 Wattimena, D. 717 Wittchen, H.U. 396 Yanagida, T. 457 von Eckardstein, A. 257, 327, 329, 345, 714 Watts, G. 355, 424 Wittenbecher, C. 412 Yang-Yen, H.F. 341 Yang, C.M. 533 Velagapudi, S. 345 Veldhof, S. 399 Velosa, A.P. 1 122 Vendrame, S. 1 105 Venn, A. 758 Verbeek, R. 680 Verhoeven, A. 717 Verkade, H.J. 804 Veronese, N. 1 029 VERSET, M. 292 Verweij, S. 81, 106 Verwilligen, R.A.F. 1 040 Willeit, J. Y 215 216 Yang, F. 339 Yurtaev, Y. 783 Zhang, J. 339 Yang, H. 464 Yuschak, S. 416 Zhang, P. 83 Yang, L. 95 Yvant-Charvet, L. 124, 304 Zhang, Q.H. Yang, X. 627, 673 Z 822, 823, 824 Yang, Z. 479 Zabakhidze, N. 844 Zhao, S. 268 Yano, S. 703, 1 135 Zafrir, B. 932 Zhelankin, A. Yarovaya, E. 629, 640 Zagajewski, J. 840 532, 1 076, 1 077 Yasuda, D. 1 002 Zagidullin, B. 1 140 Zheleznyakova, A. 868 Yayla Abide, C. 893 Zagidullin, N. 1 224 Yeang, C. 455, 673, 674 745, 907, 1 140 Zheltova, I. Zhemchugov, A. 400 Zagidullin, S. 745, 907, 1 140 Zheng, H. 452 Zheng, K.H. 547 Zagjewski, J. 1 008 Zhetisheva, R. Zago, V.H. 983 454, 526, 542 Zaibi, M.S. 849 Zhokhov, D. 850 Zak, I. 1 218 Zhou, P. 447, 873 12, 226, 725, 987, 1 029 Zhu, W. 268 Zhu, Y. 653 121, 725, 1 029 Zhuang, L. 210 Zielinski, L.P. 743 Yen, J.J.Y. 341 Yenercag, M. 984 Yersal, N. 294 Yet, S.F. 348 Yi, C. 210 Yi, G.H. 822, 823, 824 Zambon, A. Yilmaz, H. 984 Yilmaz, M. 984 Yin, X. 312 Zambonin, L. 1 022 Yin, X.L. 1 186 Ziemann, M. 1 113 Zamfirescu, A. 609, 792 Yingling, Z. 490 Zierfuss, B. 507 Zamora, A. 944 Yki-Järvinen, H. 915 Zilmer, M. 1 129 Zampelas, A. 1 092 Ylä-Herttuala, S. 37 Zimetti, F. Zampetaki, A. 312 697, 715, 1 058 Yogo, M. 693 Zannis, V. 652 Zimmer, A. 622 Yokota, T. 375 Zannouri, A. 1 174 Zimmermann, R. 282, 284 Yokoyama, S. 375, 531, 693 Zanolin, D. Zimmet, P. 1 113 yongqiang, H. 809 Zirlik, A. Yoo, J.A. 829 224, 306, 470 Yoo, J.Y. 420 Zito, C. 599 Yoshida, M. 948 366, 731, 732, 733, 839, 879, 883, 991, 1 136, 1 137, 1 138 Zivanovic, V. 821 Yoshikawa, J. 1 041 Zanotti, I. 692 Zivkovic, M. 373 Yoshikawa, K. 338 Zateyshchikov, D. 785 Zizkova, V. 1 005 Yoshino, G. 855 Zaytsev, D. 807 Zo, J.H. 512, 1 010 Yoshino, H. 855 Zdzienicka, A. 1 016 Zotikov, A. Yoshiyama, M. 1 041 Zechner, R. 92, 137 793, 906, 911, 1 023 Youn, T.J. 1 032 Zelarayán M 961 Zouhar, P. 889 467, 702 Zambon, S. Young, J.L. 493 Zelcer, N. 209, 664 Zsíros, N. Youngkeun, A. 1 200 Zelinskiy, V. 830 Zuk, M. 956 Yu, C.W. 738, 739, 1 004 Zeljković, A. 436, 741, 874 Zulkarneev, R. 1 140 Zelzer, S. 1 142, 1 143 Zuraeva, Z. 900 Zeng, L. 240 Zvintzou, E. 688 Zerr, A. 283 Zykov, K. 1 139 483 Þorgeirsson, G. 1 220 Νomikos, T. 1 115 Yu, T. 524 Yu, Y. 479, 1 021 Yuan, C. 248 Yue, J. 823 Zhang, H. 84 EAS CONGRESS th May 29 - June 1, 2016 Innsbruck, Austria Recognition, s and t n e m e g d e l w Ackno t r o pp u S l a i c r Comme www.eas2016.kenes.com 84 EAS CONGRESS th ACKNOWLEDGEMENTS PCSK9 inhibitors: a conversation on selecting the right patients CORPORATE PARTNERS gold Level Corporate Partner Programme Chair: Alberico Catapano, Italy Welcome and introduction Who is at greatest unmet need? Clinical perspective How effective are PCSK9 inhibitors in reducing LDL-C? Clinical perspective Alberico Catapano, Italy Michel Farnier, France Panel Erik Stroes, The Netherlands Panel Which patients find it hardest to achieve recommended LDL-C levels? - Familial hypercholesterolaemia - Statin intolerance: gaUSS-3 data Clinical perspective Will lowering LDL-C with PCSK9 inhibitors reduce CV risk? Closing Q&a and panel discussion Chair’s summary and close Silver Level Corporate Partner Bronze Level Corporate Partners Michel Farnier, France Erik Stroes, The Netherlands Panel Alberico Catapano, Italy Panel Alberico Catapano, Italy joint Bronze partners Lu nc 218 hb ag sw ill b ep rov Amgen (Europe) GmbH Dammstrasse 23 CH-6300 Zug Switzerland www.amgen.com ide d © 2016 Amgen Inc. All rights reserved. EUHQ-NP-145-0216-125392a 219 84 EAS CONGRESS th ACKNOWLEDGEMENTS The Organising Committee and the EAS Executive Committee would like to express their gratitude and acknowledgement to the following companies for their generous support in the 84th EAS Congress: EXHIBITORS Platinum sponsors gold sponsors silver sponsors sponsors 220 221 84 EAS CONGRESS th Industry supported sessions Sunday, May 29, 2016 12:30-13:30 Monday, May 30, 2016 Carl von Rokitansky (Brussel)Hall 13:00-14:30 Nikolai N. Anitschkow (Tirol) Hall Meet the Experts The Medical Puzzle of HoFH PCSK9 inhibitors: a conversation on selecting the right patients Chairperson: Chairperson: Alberico Catapano, Italy Cesare Sirtori, Italy • Jeanine Roeters Van Lennep, The Netherlands • Claudia Stefanutti, Italy • Marcello Arca, Italy 16:00-17:30 13:00 - Welcome and introduction Alberico Catapano, Italy 13:05 - Who is at greatest unmet need? Michel Farnier, France Nikolai N.Anitschkow (Tirol) Hall 13:15 - Clinical perspective Panel 13:20 - How effective are PCSK9 inhibitors in reducing LDL-C? Erik Stroes, The Netherlands MOVING PCSK9 INHIBITION FORWARD: The Future of Evidence-Based CV Outcomes in High-Risk Primary and Secondary Prevention Patients 13:30 - Clinical perspective Panel Chairperson: Jean-Claude Tardif, Canada 13:45 - Statin intolerance: GAUSS-3 data Erik Stroes, The Netherlands 16:00 - Welcome and Introductions Jean-Claude Tardif, Canada 13:55 - Clinical perspective Panel 16:05 - Case-Based Approach to Identifying High-Risk Primary and Secondary Prevention Patients Michel Farnier, France 14:05 - Will lowering LDL-C with PCSK9 inhibitors reduce CV risk? Alberico Catapano, Italy 16:25 - Current Guidelines for High-Risk Patients: The Need for Evidence-Based Decision Making to Address Remaining Unmet Need G Kees Hovingh, The Netherlands Which patients find it hardest to achieve recommended LDL-C levels? 13:35 - Familial hypercholesterolaemia Michel Farnier, France 14:15 - Closing Q&A and panel discussion Panel 14:25 - Chair’s summary and close Alberico Catapano, Italy 16:45 - Cardiovascular Risk Reduction With PCSK9 Inhibition: Evidence-Based Long-Term CV Outcomes Jean-Claude Tardif, Canada 17:05 - Panel discussion/Q&A 222 223 84 EAS CONGRESS th 13:00-14:30 Karl Landsteiner (Innsbruck) Hall LDL-Cholesterol Update 2016 Chairpersons: Lale Tokgözoglu, Turkey Pepe Zamorano, Spain 13:00 -Welcome and Introduction – What’s Hot 2016 Lale Tokgözoglu, Turkey Pepe Zamorano, Spain 13:10 - The Clinical Reality – Attaining Treatment Targets in 2016 Lale Tokgözoglu, Turkey Tuesday, May 30, 2016 13:00-14:30 Karl Landsteiner (Innsbruck) Hall PCSK9 therapeutics – can we redefine the clinical management of hypercholesterolemia? Chairperson: John Chapman, France 13:00 - Introduction John Chapman, France 13:20 -What Do Recent Combination Studies Teach Us? – The Most Recent Insights Peter Toth, USA 13:05 - PCSK9 therapeutics – the evidence so far Eli Roth, USA 13:45 -Novel Findings on Genetics and Mendelian Randomization Heribert Schunkert, Germany 13:25 - PCSK9 therapeutics – early insights from the correlation between LDL-C and cardiovascular events Kausik Ray, UK 14:00 - The Role of Combination Therapy – Defining Treatment Options for the Individual Patient Pepe Zamorano, Spain 14:15 - Panel Discussion Lale Tokgözoglu, Turkey Pepe Zamorano, Spain 13:45 - PCSK9 therapeutics - what do we have yet to learn? Ulrich Laufs, Germany 14:05 - Panel Discussion and Q&A John Chapman, France Eli Roth, USA Kausik Ray, UK Ulrich Laufs, Germany 14:25 - Closing remarks John Chapman, France 224 225 84 EAS CONGRESS th 14:00-14:45 Nikolai N.Anitschkow (Tirol) Hall Special Lecture: Novel Concept and Clinical Proof to Address Unmet Medical Needs for the Treatment of Rasidual Vascular Risk Chairpersons: Yuji Matsuzawa, Japan Jean-Charles Fruchart, France 14:00 Welcome and Introduction Yuji Matsuzawa, Japan Jean-Charles Fruchart, France 14:05 Novel generation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) agonists: selective PPARα modulator (SPPARMα) Jean-Charles Fruchart, France 14:25 Clinical proof of concept of SPPARMα developed to be more effective and less harmful Shun Ishibashi, Japan 14:10-14:55 Carl von Rokitansky (Brussel) Hall CETP inhibition – what’s hot in 2016? Chairperson: Alberico Catapano, Italy 14:10 Opening by the chair Alberico Catapano, Italy 14:15 The pharmacologic basis: Recent insights into kinetics Gisette Reyes-Soffer, USA 14:25 Facts, Findings & Expectations Ulf Landmesser, Germany 14:35 Is there a need for a new small molecule? Wouter Jukema, The Netherlands 14:45 Round Table, Q&A Alberico Catapano, Italy 14:05-14:50 Wilhelm Auerswald (Strassburg) Hall MeEt the Expert: Introducing Sebelipase alfa, a novel treatment for LAL-D A case-based meet-the-expert session chaired by Professor Thomas Stulnig Experts will present cases on Lysosomal Acid Lipase Deficiency including early treatment results with Sebelipase alfa. 226 227 84 EAS CONGRESS th Educational Grant Exhibition Information The following session is supported by an Educational Grant. EXHIBITION MAP Monday, May 30, 2016 N. Anitschkow Hall 18:40-19:40 Keynote Lecture Supported by Amgen, AstraZeneca, MSD, Pfizer, Regenron and Sanofi. Chair: Alberico Catapano (Italy) Chair: Wolfgang J. Schneider (Austria) 18:40 How genes control cholesterol Michael S. Brown (USA) EXHIBITORS LIST Company Name 22 Alexion Pharma 2 Amgen 18 Denka Seiken European Atherosclerosis Society 228 Booth # Akcea Therapeutics 8 10 and 25 European FH Patient Network 5 FH SCORE 23 Fujifilm VisualSonics 12 Immuno-Biological Laboratories 7 Kaneka Pharma Europe 6 Meda Pharma 17 Merck MSD 1 Mercodia 24 Nebion 4 Numares Health 9 Randox 21 Sanofi Regeneron 20 Wisepress Medical Bookshop 26 229 84 EAS CONGRESS th List of Sponsors, Supporters & Exhibitors Aegerion YOU’VE ONLY JUST ARRIVED & ALREADY WE’RE THINKING OF YOUR NEXT TRIP As the official airline network for EAS 2016, we’d like to thank you for choosing the Star Alliance network and hope that all goes really well for you here today. Whilst you concentrate on the day’s events, we hope you’ll consider us the next time you need to attend a conference. With over 18,500 flights a day to 1,330 airports across 192 countries, our 28 member airlines will extend a wide choice of flights to any future conference you’re planning to attend. And no matter which of those airlines’ frequent flyer programmes you belong to, you can earn and redeem miles across all of them. Aegerion Pharmaceuticals Inc One Main St, Suite 800 Cambridge MA 02142 USA http://www.aegerion.com Aegerion Pharmaceuticals, headquartered in Cambridge, Massachusetts, is a biopharmaceutical company dedicated to the development and commercialization of innovative therapies for patients with debilitating rare diseases. The Company was founded in 2005 with an initial focus of bringing new therapies to patients with severe lipid disorders and is now focused on research, development, commercialization of orphan drugs for the treatment of debilitating rare diseases. Akcea Therapeutics 55 Cambridge Parkway, Suite 100 Cambridge 02142 USA Booth #: 22 http://www.akceatx.com Akcea Therapeutics is a development and commercialization company focused on transforming the lives of patients with serious cardiometabolic lipid disorders. Established as a wholly-owned subsidiary of Ionis Pharmaceuticals, Inc., Akcea’s portfolio spans multiple targets and disease states using advanced RNA-targeted antisense therapeutics. Akcea’s investigational pipeline includes novel drugs designed to reduce several lipid risk factors, including LDL-Cholesterol, apoC-III, triglycerides and Lp(a). Volanesorsen, Akcea’s most advanced investigational drug, is in Phase 3 trials for ultra-orphan lipid disorders characterized by extremely high triglycerides and apoC-III, including familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy (FPL). www.akceatx.com. So the next time you want to concentrate all your energies on your conference, we hope you’ll decide to leave the travel arrangements to us. www.staralliance.com Information correct as of 03/2016 230 231 84 EAS CONGRESS th Alexion Pharma AstraZeneca Giesshübelstrasse 30 Zürich 8045 Switzerland Booth #: 02 http://www.alexionpharma.eu Alexion is a global biopharmaceutical company focused on developing and delivering lifetransforming therapies for patients with devastating and rare diseases. Patients with these life-threatening diseases often have no effective treatment options, and they and their families suffer with little hope. Our goal is to deliver medical breakthroughs where none currently exist. We are driven because we know people’s lives depend on our work. SE-43183 Mölndal, Pepparedsleden 1 Sweden www.AstraZeneca.com AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. AMGEN DAMMSTRASSE 23 ZUG 6300 Switzerland Booth #: 23 http://www.amgen.com Amgen’s Commitment to Cardiovascular Disease Amgen is dedicated to addressing important scientific questions to advance care and improve the lives of patients with cardiovascular disease. Amgen has built a robust cardiology pipeline in an effort to address a number of today’s important unmet patient needs, such as high cholesterol and heart failure. About Amgen Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. Amgen has grown to be the world’s largest independent biotechnology company, reaching millions of patients around the world. Amgen EU HQ Dammstr. 23 Zug 6301 Switzerland Booth #: 18 http://www.amgen.com Amgen’s Commitment to Cardiovascular Disease Amgen is dedicated to addressing important scientific questions to advance care and improve the lives of patients with cardiovascular disease. Amgen has built a robust cardiology pipeline in an effort to address a number of today’s important unmet patient needs, such as high cholesterol and heart failure. About Amgen Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. Amgen has grown to be the world’s largest independent biotechnology company, reaching millions of patients around the world. 232 BASF Carl-Bosch-Strasse 38 Ludwigshafen,Rhineland-Palatinate Germany website: http://www.basf.cm www.newtrition.com BASF’s Nutrition & Health division develops, produces and markets a comprehensive range of products and services for the human and animal nutrition, pharmaceutical as well as flavor and fragrance industries. The division strives to contribute to a better life through improving the nutrition, health and wellbeing of people across the world. Important human nutrition products are vitamins and carotenoids, plant sterols, emulsifiers and omega-3 fatty acids. Its feed additives such as vitamins, carotenoids, enzymes and organic acids make Nutrition &Health a worldwide leader for the animal nutrition market. The division provides the pharmaceutical industry with active ingredients such as caffeine and ibuprofen, as well as excipients and custom synthesis services. Furthermore, it produces aroma ingredients such as citral, geraniol and L-menthol for the flavor and fragrance industry. Denka Seiken Co., Ltd Nihonbashi Mitsui Tower, 2-1-1 Nihonbashi-Muromachi Tokyo 103-8338 Japan Booth #: 08 http://denka-seiken.jp Denka Seiken offers assays directly quantifying (without any sample pretreatment) lipid subfractions, and also latex-enhanced turbidimetric immunoassays for specific protein biomarkers to be run on automated chemistry analyzers. The range of lipid subfraction assays includes small dense LDL, HDL3, Remnant Lipoproteins and Triglycerides in LDL particles. The latex-enhanced turbidimetric immunoassays are available for Adiponectin, Lp(a), Cystatin C, hsCRP, RF, Myoglobin, IgE, Ferritin, etc. 233 84 EAS CONGRESS th European Atherosclerosis Society Mässans gata 18/ Box 5243 Gothenburg 40224 Sweden Booth #: 10 http://www.eas-society.org Advancing and exchanging knowledge of the causes, natural history, treatments and prevention of atherosclerotic disease. FH Europe 7 North Road Maidenhead SL6 1PE UK Booth #: 05 http://www.fheurope.net FH Europe is the European FH Patient Network, consisting of 20 European patient organisations. We actively work to secure early identification and diagnosis of FH patients to prevent early cardiovascular disease. Our vision is to identify all FH patients across Europe and for them to be optimally treated in order they may live a full and healthy life. We were founded in 2015 and have successfully achieved a number of activities, including launching a Call to Action at the European Parliament in Brussels, we contributed to videos and articles about FH, attended health care professional meetings to raise awareness of the network and held a meeting of all countries to share best practice. FUJIFILM VisualSonics 3080 Yonge Street Suite 6100 Toronto M4N3N1 Canada Booth #: 12 http://www.visualsonics.com FUJIFILM VisualSonics, Inc is the undisputed world leader in high-resolution, microultrasound systems designed for cardiovascular research. Our Vevo systems operate at 10-70 MHz, achieving up to 30 μm resolution, 5-10 times higher than any other ultrasound system. Our small animal handling platforms captures key physiological parameters including temperature, respiration, ECG and heart rate. These are integrated in real-time with echo images and data. VisualSonics platforms combine high-resolution, real-time, in vivo imaging at reasonable cost with ease-of-use and quantifiable results. 234 Immuno-Biological Laboratories Co., Ltd. (IBL) 1091-1 Naka Aza-Higashida, Fujioka-Shi, Gunma 375-0005 Japan Booth #: 07 http://www.ibl-japan.co.jp/en/ “LipoSEARCH” is a sophisticated comprehensive lipoprotein profiling service (using HPLCbased system) that can deliver a reliable and promising complete set of data on Cholesterol and Triglyceride profiled in 4 major classes (CM, VLDL, LDL and HDL) and 20 subclasses classified by particle size. In addition, it also can deliver number of the particles that is recognized as an important factor in recent international research of atherosclerosis and dyslipidemia. The proprietary system and service ”LipoSEARCH” is operated and provided by Skylight Biotech Inc. who is owned by Immuno-Biological Laboratories Co., Ltd. located in Japan. Kaneka Pharma Europe N.V. Frankfurter Straße 80-82 Eschborn 65760 Germany Booth #: 06 http://www.kanekapharma.com Kaneka Corporation is touching the lives of people all over the world with infinite possibilities of chemistry. By further enhancing our key of highly innovative technology in producing medical devices and building blocks for active pharmaceutical ingredients (API), macromolecules, fermentation and bioscience, Kaneka is exploring new possibilities beyond the traditional boundaries of chemistry. Kaneka Pharma Europe N.V. (KPE) is the independent subsidiary responsible for the European market. Lipoproteinapheresis (Lp(a), LDL), in which Kaneka is one of the pioneers since 1989, is beside the interventional products one of KPE’s main business. 235 84 EAS CONGRESS th KOWA 6-29, Nishiki 3-chome, Naka-ku, Nagoya, Aichi 460-8625 Nagoya 460-8625 Japan http://www.kowa.co.jp/eng/ Kowa Company, Ltd. (Kowa) is a privately held multinational company headquartered in Nagoya, Japan. Established in 1894, Kowa is actively engaged in various manufacturing and trading activities in the fields of pharmaceuticals, life science, information technology, textiles, machinery and various consumer products. Especially, the pharmaceutical field is positioned as the key business segment; prescription (ethical drug), Over-the-Counter (OTC) / Consumer Healthcare / Dietary supplement and Medical equipment. Moreover, the pharmaceutical R&D division is focused on research and development for cardiovascular therapeutics (dyslipidemia, type 2 diabetes and atherosclerosis), ophthalmology and antiinflammatory agents. To visit Kowa Company, Ltd.’s website, please visit www.kowa.co.jp/ eng Mercodia AB Sylveniusgatan 8A Uppsala 75450 Sweden Booth #: 24 http://www.mercodia.com Mercodia AB is a Swedish biotech company focusing on the development of immunoassays for research within the field of metabolic disorders. Our assays are applicable to both animal and human models and are used for research ranging from basic scientific studies to large pre-clinical and clinical phase trials. The company was founded in 1991 and is today a world-leading supplier of products to all major international markets. More than ninety percent of our production is exported from our facilities in Uppsala to approximately 100 different countries around the world. MSD MEDA PHARMA S.P.A. Via Valosa di Sopra, 9 Monza 20900 Italy Booth #: 17 http://www.meda.se Meda is a leading international pharma company with a broad product portfolio. The nutraceuticals developed fall into the same therapeutic categories in which Meda has a wealth of experience. The cardiovascular area of nutraceuticals is represented by Armolipid product line (patented), dietary supplements with natural substances for the control of lipids when integrated in an adequate diet for such purposes. The ingredients of Armolipid line derive from high quality natural extracts with very well documented activity. The production process follows pharmaceutical quality standards, every product is clinically tested and the results of clinical trials published in peer-reviewed international medical journals. 236 2000 Galloping Hill Road Kenilworth 07033 USA Booth #: 01 http://www.msd.com Today’s MSD is a global healthcare leader working to help the world be well. MSD is known as Merck in the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. MSD. Be well. For more information, visit www.msd.com Mylan Building 4 Trident Place Mosquito Way Hatfield AL10 9UL UK http://www.mylan.com/ Mylan is one of the world’s leading global pharmaceutical companies. Our medicines include generic and brand name products in a variety of dosage forms and therapeutic categories, such as difficult-to-manufacture injectables, transdermal patches and HIV/AIDS antiretroviral therapies. The company has innovative research and development capabilities and is one of the world’s largest active pharmaceutical ingredient manufacturers. Mylan applies one global quality standard to all of our medications regardless of where they are produced. Creating better health for a better world. That’s what inspires Mylan in our mission to provide quality healthcare to the world’s 7 billion people, one person at a time. 237 84 EAS CONGRESS th numares AG Randox Biosciences Am BioPark 9 Regensburg 93053 Germany Booth #: 09 http://www.numares.com numares HEALTH develops innovative, in vitro diagnostic (IVD) tests running exclusively on the AXINON® System. AXINON® relies on numares’ proprietary MGS® technology for generating reproducible, quality controlled metabolic information using nuclear magnetic resonance (NMR) spectroscopy. The AXINON® software makes this information based on disease-specific metabolic profiles easily accessible for in vitro diagnostics. The integration of different tests into one system makes AXINON® a highly flexible tool for various diagnostic questions. The new IVD test lipoFIT-S100 (CE) determines clinically proven lipoprotein parameters such as LDL-P and sdLDL in high throughput. Further tests for various indications (e.g. nephrology, oncology) are in development. 55 Diamond Road Crumlin BT29 4QY UK Booth #: 21 http://www.randoxbiosciences.com/ Randox Biosciences is dedicated to improving health worldwide through scientific discovery, drug development and diagnostics. We offer a range of molecular products that provide diagnostic, prognostic and predictive solutions across a variety of disease areas including cardiology (cardiac risk prediction) and inherited disease. Our Familial Hypercholesterolemia Arrays l & ll enable the simultaneous detection of 40 FH-causing mutations within the LDLR, ApoB and PCSK9 genes. Utilising our award winning Biochip Array Technology for multi-analyte screening of biological samples, our assays provide a complete patient profile from a single sample for rapid, accurate diagnosis. Raisio REGENERON P.O. Box 101, FI-21201 Raisio, Finland Website: www.raisio.com Benecol® - proven to reduce cholesterol Raisio Group is an expert in plant-based nutrition with strong international and local food brands. Benecol® is the expert brand in cholesterol reduction and a pioneer in the cholesterol lowering functional food category. Raisio Group produces the unique cholesterol-lowering ingredient, Plant stanol ester, and licenses the Benecol brand worldwide. Benecol products are manufactured and sold by local food companies in 30 countries on five continents. Over 70 clinical studies support the use of Benecol as an effective, easy and safe dietary tool to lower LDL-cholesterol. The cholesterol-lowering effect of Benecol is additive to those of a healthy diet and statin medication. 777 Old Saw Mill River Road Tarrytown, NY 10591 USA Booth #: 20 http://www.regeneron.com Regeneron (NASDAQ: REGN) is a leading science-based biopharmaceutical company based in Tarrytown, New York that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for high LDL cholesterol, eye diseases, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain and infectious diseases. SANOFI 54, av. La Boétie Paris 75008 France Booth #: 20 http://en.sanofi.com/ Sanofi, an integrated global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme. Sanofi is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY) 238 239 84 EAS CONGRESS th 84th European Atherosclerosis Society Congress Wisepress Medical Bookshop 25 High Path London SW19 2JL UK Booth #: 26 http://www.wisepress.com Wisepress.com, Europe’s leading conference bookseller, has a range of books and journals relevant to the themes of the meeting. In addition to attending 200 conferences per year, Wisepress has a comprehensive medical and scientific bookshop online with great offers. Follow us on Twitter for the latest news @WisepressBooks. MEET-THE-EXPERT SESSION Introducing Sebelipase alfa, a novel treatment for LAL-D Placing the spotlight on Lysosomal Acid Lipase Deficiency A case-based Meet-the-Expert session chaired by Professor Thomas Stulnig (Vienna, Austria) Experts will present cases on Lysosomal Acid Lipase Deficiency including early treatment results 31 May 2016; 14:05–14:50 Wilhelm Auerswald (Strassburg) Hall, Congress und Messe Innsbruck, Innsbruck, Austria 240 EMEA/UNB-LAL/16/0054 241 84 EAS CONGRESS th notes 242 243 84 EAS CONGRESS th notes 244 245 84 EAS CONGRESS th notes 246 247 notes EAS INTERNATIONAL EVENING The EAS International Evening Networking event in Innsbruck will take place at Congress Park Igls Tuesday, May 31, 2016 at 19:30 Tickets are subject to availability and can be purchased at the registration desk. Transportation Buses will leave from the front of the Congress Centre at 18:45 We look forward to welcoming you 248