CGHUB: Kick-starting the WORLDWIDE GENOME WEB

CGHUB: Kick-starting the WORLDWIDE GENOME WEB

GHUB: Kick-starting the
WORLDWIDE GENOME WEB
2013
uary 13, 2013
Worldwide Web Maturity
TRANSFORMATION
HTTP
WAIS
GOPHER
FTP
>> LEVEL OF SOPHISTICATION >>
The Worldwide Genome Web
Patients
Physicians
User Interfaces
Portal
Virtual Catalog
Provider Org’s
Pharma
Machine Learning &
semantics
Public/Private Cloud
Payers
Annai BiointelligentTM Network
Researchers
Genomic Sequen
& Analysis Cente
Worldwide Genome Web Maturity
TRANSFORMATION
DISTRIBUTION
TRANSMISSION
ACCESS
STORAGE
>> LEVEL OF SOPHISTICATION >>
CI Cancer Genome Network
100+ Hospitals
2 Sample Biocenters
CGHub
10 Sequence Centers
ancer Research Network Users
Annai Biointelligent Network
CGHub
1000 Genomes
TCGA
Target
Public
Repos
Private
Repos
Commercial
Repos
200+ Research Institutes Worldwide
eneTorrent Data
ransfer Performance
Protocol Comparison
CGHub Download
Usage Numbers
12/2011 – 12/2012
304,735 4.4
638
437
435
100
15
FTP
GridFTP +ssl
GridFTP -ssl
GeneTorrent GeneTorrent +ssl
ssl
Gigabits/second
ak aggregate concurrent bandwidth
total files
transferred
petabytes
transferred
321TB+ 24,00
total genomic
data available
genome
sequences
GeneTorrent – High Performance Protocol
GeneTorrent Leverages BitTorrent
BitTorrent Used by
ENETORRENT PARALLELISM
ransferring Genome Data with GeneTorrent
ecuring GeneTorrent Transfers
Advancing Research with the WGW
Take-aways
GW and
eneTorrent
ve been deployed
r over a year
Network
is operating
at scale
Expected to grow
significantly
this year
Used by basic &
clinical researchers
pharmaceuticals,
and commercial
analytics companie
CKNOWLEDGEMENTS
UCSC
Annai Systems
NCI/NHGRI
Mark Diekhans
rich Weiler
inda Rosewood
aifang Telc
ohn Groboske
lizabeth Mitchell
aniel Wilson
rian Craft
rad Smith
m Warner
avid Haussler (PI)
Christy Martin
Dan Murphy
Howdy Pierce
Donavan Nelson
Lori Louie
Brian Litzinger
Dan Maltbie (CTO)
Kenna Shaw
Heidi Sofia
Leonie Misquitta
Liming Yang
CONTACT:
Chris Wilks <[email protected]>
Dan Maltbie <[email protected]>