Publication

Campbell
FA L L 2 0 1 5
I N M OT I O N
STORY
A New
De st i nat ion
fo r Sp i ne Care
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NEWS
C l inic
Re se a rc h
R a mp s Up
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
F RO M C H IEF O F S TA FF F REDERICK M. AZAR, M. D.
DEAR FRIENDS AND COLLEAGUES,
Welcome to the Fall edition of Campbell in
Motion, our newsletter highlighting Campbell
Clinic and The Campbell Foundation!
As we near the close of 2015, I’ve reflected
back in recent days upon what has been
an exciting and successful year for our
organization. We’ve made some significant
additions, including the launch of our fifth
clinic location in Cordova. The feature article
in this issue provides more detail about that
facility – Campbell Spine Center – which
opened to the public late this past spring.
We’ll also introduce you to Norfleet B.
Thompson, M.D., the newest physician to join
the Campbell Clinic family. Dr. Thompson
graduated from The University of Tennessee
Medical School and completed his residency
through the UT-Campbell Clinic program
in 2014.
From the very beginning, a commitment to
education, research and community outreach
has been a hallmark of The Campbell
Foundation. That legacy continues today,
and some of our recent work in this area is
detailed here as well.
I join our clinic and foundation employees
in wishing you the best as we enter the
holiday season, and we hope that this year
has been a blessed and prosperous one
for you. During this season of thanks, we
are very appreciative of our partners in
the community who help Campbell Clinic
continue to provide orthopaedic care to the
Mid-South. We are grateful for your support.
WISHING YOU THE BEST,
FREDERICK M. AZAR, M. D.
Chief of Staff, Campbell Clinic Orthopaedics
IN THIS ISSUE
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F E AT U R E S T O R Y
IN THE NEWS
P U B L I C AT I O N S
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
A NEW
DESTINATION
FOR SPINE
CARE
C A M P B E L L C L I N I C A D DED I TS
F I F TH LO C ATI O N I N TH E S PRI NG
Patients suffering from back and spine
problems were given a new option for
recovery in late spring 2015 when the
Campbell Clinic Spine Center opened
in Cordova, an eastern suburb of
Memphis, Tenn.
The 18,000-square-foot facility, located
in the Germantown Park office complex
at 8000 Centerview Parkway, opened
its doors to patients as the first
exclusively sub-specialized office in the
clinic’s history.
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
The facility combines state-of-the-art
technology with a fully dedicated spine
staff to streamline the patient experience
and make the clinical process more
efficient for both patients and providers.
Campbell Clinic’s three spine surgeons,
five physiatrists, and a mid-level provider
all now work primarily from the new clinic.
Those physicians team up with clinical
and ancillary employees, as well as backfocused physical therapists, to provide
a “one-stop-shop” for patients with
debilitating back problems.
“We’re able to treat a full spectrum of
spinal disorders and injuries at the Spine
Center,” said Dr. Keith Williams, a physician
who has moved his practice to the new
center. “The resources we have in place
allow us to provide a continuum of care
that is efficient and convenient for
our patients.”
In addition to the various amenities at the
new clinic, that network also includes the
organization’s Germantown facility located
less than two miles from the Spine Center.
The Germantown clinic houses an MRI
suite and also has an ambulatory surgery
center on its campus. For patients who
need to get an MRI or are candidates for
outpatient spine surgery, the proximity of
the two clinics has been an asset.
The center, which occupies most of
the Fifth Floor suite in its complex,
was specially designed to provide an
exceptional patient experience with
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forward-thinking clinical benefits. The
floor plan employs a conceptual layout
that guides patients through every step
of the process so that they’re always
advancing and never retrace their steps
from reception to triage to the exam
room. The exam rooms are more private
than those in a typical physician’s office
because they’re set apart from the
nurse’s station and other clinical areas
occupied by medical personnel.
“From the beginning of the design
process, our goal was to create a
warm, welcoming environment where
patients would feel comfortable and
relaxed, but also confident in the care
they’re waiting to receive,” said Valerie
Patterson, Director of Operations at
Campbell Clinic. “We considered all
elements, including what should be
“on-stage” for patients as well as what
should be hidden from view. The result
is a streamlined, integrated approach to
patient care.”
Even the clinic’s waiting area received
unique attention when it was designed.
When patients enter the facility, they’re
guided to check in either for a clinic
visit or physical therapy appointment.
From there, they’re diverted to a
community waiting area that features
usable workspace and wireless Internet
connectivity for busy patients on the go.
Patients receive iPad tablets that enable
them to fill out typical office forms
digitally, which speeds up the registration
process. The clinic also features a
secluded “quiet area” with additional
work stations that offers the comfort of a
typical business center at an upscale hotel.
Campbell Clinic CEO George Hernandez
sees operational benefits as well as
experiential ones. “We have consolidated
our spine-related providers and
equipment to provide a comprehensive
approach, which lowers overhead for the
clinic,” he said. “We know our patients stay
active and busy, and they value the ability
to come to one place to have their needs
assessed and treated. It can certainly
help cut down on their number of
office visits.”
For more information about
Campbell Clinic Spine Center, visit
www.campbellspinecenter.com or call
office manager Pam Reece at
(901) 507-7650.
Q U I C K FA C T S :
Opened: Spring 2015
Patient Visits: 8,685
Physicians: 8
Clinic Staff: 16
Conditions Treated:
Herniated discs, degenerative disc disease,
bone spurs, spinal tumors, stenosis, neck
and arm pain, back pain, and other
complex spine disorders
Amenities:
Spacious waiting area and patient
workspace, physical therapy suite, procedure
room, X-ray suite, private exam rooms
From left to right:
Spine Surgeons: Francis X. Camillo, M.D.,
Raymond J. Gardocki, M.D., Keith D. Williams, M.D.
Physical Medicine and Rehabilitation Physicians:
Douglas T. Cannon, M.D., J. Dee Dockery, M.D.,
Santos F. Martinez, M.D., Ashley L. Park, M.D.,
Carlos E. Rivera, M.D.
Physician Assistant (not pictured): Pooja S. Peters, P.A.
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
Patient Sydni Aylor with
Pediatric Orthopaedic
Surgeon Jeffrey Sawyer, M.D.
Campbell team has become a publishing
powerhouse, producing nearly 10 peerreviewed publications every month on a wide range of orthopaedic clinical
topics — but all centered on pediatric
orthopaedic results and ways to optimize
outcomes, despite adverse patient factors.
CAMPBELL FOUNDATION
In the News
DONOR SUPPORT FUELING
RESEARCH GROWTH
108
TRANSISTORS PER CHIP
Donor Support Fueling Research Growth.
There’s a truth in the world of computing
technology known as Moore’s Law, named
for Gordon E. Moore, one of the founders
of Intel, who observed that the number of
transistors on integrated circuits doubles
approximately every two years. This law is
now used in the semiconductor industry
to guide long-term planning and to set
research targets for product development.
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- Campbell Foundation Trustee Larry Papasan
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DATE
MOORE’S LAW
Research output at the Campbell Foundation has followed a similar trajectory to
Moore’s Law — doubling every two years. Just five years ago, in 2010, the research
output here was limited. Our resources were divided, we had “outsourced” some of
our testing, and our efforts were not focused. At the urging of several members of the
Campbell Foundation Board of Trustees, researchers were encouraged to thoughtfully
consider what they wanted to impact, to focus on what they could become worldexperts on, and to diligently work at it. In addition, critical donor support helped build
an infrastructure that would accelerate the work by supporting things like supplies,
research assistants, biostatistics work, and guidance and expertise in manuscript
development. The entire effort has led to an exponential growth in research output.
“It is most impressive,” says Campbell Foundation Trustee Larry Papasan. “I’ve always
been a big believer in strategic planning, and when the doctors strategically looked
at their practice, they began to see trends and areas where research from the team
at Campbell could really make a difference. They focused on clinical orthopaedic
conditions that they see often, and therefore, things they do really, really
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“When the doctors strategically
looked at their practice, they
began to see trends and areas
where research from the team at
Campbell could really make
a difference.”
well. And they also saw patient factors —
things that weren’t due to something the
surgeon did, or the design of the implant,
but instead were due to behaviors or
health conditions of the patients, and
they really began to dive into the details.”
The result was a focus in two key areas:
pediatric orthopaedics and patient
factors research. All the orthopaedic
subspecialties began to segment their
clinical data, to look at those other issues
— things like whether the patient smokes
or might be vitamin D deficient or is obese
— to determine the outcome of treatment,
and, more importantly, to discover ways to
optimize results in spite of those factors.
As a result of this focus, and with
dedicated donor support, the
In addition to turbo-charged clinical
research, the team is working on several
exciting projects at the basic science
(cellular) level too, with PhD colleagues
within the UT-Campbell Clinic Department
of Orthopaedic Surgery & Biomedical
Engineering. In addition to the patient
factors work by the clinical team, the
researchers in the lab are examining
genetic differences among total joint
patients to predict which patients might
have a hypersensitivity to total joint
wear debris.
“A more personalized or patientcentered approach may improve
outcomes after surgery for
these patients.”
- William M. Mihalko, M.D., Ph.D.
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
“We are investigating the hypothesis
that some patients who have had a joint
replacement with a poor outcome have a
genetic predilection that we can determine
preoperatively,” says William M. Mihalko,
M.D., Ph.D., who holds the Hyde Chair in
Biomedical Research in the UT-Campbell
Clinic Department of Orthopaedic Surgery
and Biomedical Engineering. “Some
patients appear to have a hypersensitivity
reaction to the implant materials, corrosion
byproducts and/or wear debris that is
generated during the normal life of a joint
implant. We are currently investigating the
association of these types of reactions with
the presence of higher levels of certain
biomarkers either in the local joint fluid
environment or present in the circulating
serum. If we can determine the genetic
predilections that are associated with
certain joint replacement poor outcomes
then a more personalized or patientcentered approach may improve outcomes
after surgery for these patients.”
Image showing lab model (mouse) showing uptake
of fluorescent markers in the damaged cartilage, in
a loaded setting.
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Total Joint Patient
Dana Carter
“It’s amazing to think what
these discoveries could mean.....
That’s why I continue to support
research at the Campbell
Foundation. It’s not for me; it’s
for my loved ones.”
- Campbell Foundation Trustee Larry Papasan
Also, the team is looking at ways to
diagnose early stages of arthritic joint
changes — vastly earlier than can be
done presently — using microscopic
“nanoparticles” that target and bind to
areas of damaged cartilage and then
“fluoresce” - like beacons for physicians highlighting the damage. If the surgeons
can diagnose the damage much earlier,
they then will be able to treat it using the
same nanoparticle technology, delivering
targeted therapeutic medicines to the
site of the eroded cartilage in a patient’s
joint. The science is very early, proven so
far only in mice, but exhibits tremendous
promise. For the one million patients each
year who need joint replacement, and the
hundreds of millions more who have early
joint destruction, results from this research
could be revolutionary.
But the work is still in the early stages,
and with each discovery, a dozen more
questions emerge, and the research
doubles again. More discoveries, more
questions, and more late hours in the lab
testing hypotheses again and again. This
is Moore’s Law, applied to orthopaedic
research, and happening every day, led by
amazing physicians and researchers right
here in Memphis.
“It’s amazing to think what these
discoveries could mean,” continues
Papasan. “I, myself, have had total knee
replacement, and my pain is gone, and
my mobility has been restored, but it was
major surgery. It’s exciting to think that
one day it might be possible for my son or
my granddaughter to instead go in for a
‘tune up’ with an injection of therapeutic
nanoparticles to repair their knee and
not need total joint replacement. That’s
why I continue to support research at the
Campbell Foundation. It’s not for me; it’s
for my loved ones.”
Targeted fluorescent markers used in fluorescent
arthroscopy (keyhole surgery) to allow physicians
to visualize areas of cartilage damage.
Donor support to the Campbell
Foundation can accelerate more
discoveries. A new research fund,
The Canale Presidential Research Fund,
was established in 2015. The purpose of
this fund is to perpetuate the dedication
to research that is spearheading such
exciting work.
You can support ongoing discoveries
with your gift today. You may donate
online through our secure website:
campbell-foundation.org, or by
calling the Campbell Foundation
at (901) 759-5490.
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
2015 Kappa Delta Research Interns with their
Mentor, Dr. Karen Hasty, and representatives
from Kappa Delta Sorority.
ATTRACTING WOMEN TO
ORTHOPAEDICS
Dr. Karen Hasty fondly recalls her time
in college, as a member of Kappa Delta
Sorority. “Being part of Kappa Delta gave
me a close circle of female friends, and
some lifelong principles for honoring
these relationships,” Hasty says. “Little did
I know then, that I would be working in
orthopaedics - which was the philanthropy
of my sorority. The Kappa Delta Award
given each year at the annual meeting of
the American Academy of Orthopaedic
Surgeons is like the ‘Nobel Prize’ in
orthopaedic research.”
Hasty, who holds the George Thomas
Wilhelm Endowed Professorship in
the UT-Campbell Clinic Department
of Orthopaedic Surgery & Biomedical
Engineering, also may not have predicted
during her college days the role she
would play in planting seeds for a love of
orthopaedic research in bright, energetic
members of her beloved sorority.
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“Each year working with the Kappa Delta
Foundation,” Hasty says, “we have a
very competitive application process to
accept four of the most diligent, bright
and energetic Kappa Delta sisters for a
6-week term in our labs. These women
participate in our research projects, and
are genuine contributors. We thoroughly
enjoy having them with us. They bring a
joyful enthusiasm that rekindles the feeling
of discovery that led me into research in
the first place.”
“These women are very bright,
motivated, and are the kind
of researchers we need in
orthopaedics. We also need them
to help the millions of future
orthopaedic patients.”
FOOT PR I N T S I N MOT I ON AC ROSS T H E GL OBE
“I heard a great presentation by local businessman Bill Courtney on the responsibility of
a business leader to give back to his community,” says Daniel Shumate, CFO of Campbell
Clinic. “Bill is known for leading a previously losing high school football team, in an
impoverished area of Memphis, to a winning season. The movie, ‘Undefeated’ was made
about his experience. But more important than winning, the movie told the story of how
Courtney molded these young men into fine adults, capable of great things. I had the
chance to hear him talk about ‘doing what you can,’ and it really got me thinking.”
“There is so much more we can do.”
- Dr. Eric Bowman, Campbell Foundation
Resident-in-Training
Dr. Eric Bowman examines
Honduran patient with a
member of the medical
mission team.
- Karen Hasty, Ph.D., Professor
The experience culminates in term-end
presentations of their findings for the
research team. From genetic exploration
of the causes of inflammatory arthritis,
to genetic signaling pathways for bonebuilding proteins within cells, the projects
are significant and in-depth.
Patients waiting in Honduran
Orthopaedic Clinic at
beginning of day.
“It’s my hope that this experience
will pique these women’s interest in
orthopaedic medicine,” Hasty says, “and
they will be motivated to apply to the
Campbell Foundation residency. “These
women are very bright, motivated, and
are the kind of researchers we need in
orthopaedics. We also need them to
help the millions of future orthopaedic
patients.”
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“They were thankful even if we
had to tell them that we wouldn’t
be able to do their surgery this
year, on this trip.”
- Eric Bowman, M.D.
Kilimanjaro Christian
Medical Centre
Drs. Eric Bowman of Memphis, Bryce
Foster of San Antonio, Gordon Newbern
of Little Rock and support staffers Crista
Bowman and Jenna Rogers visit a hospital
patient in his 50s on whom the team
performed a hip replacement while on
a medical mission trip in Tegucigalpa,
Honduras.team performed a hip
replacement while on a medical mission
trip in Tegucigalpa, Honduras.
And, in that instant, the idea of a
community service scholarship was born.
Shumate continues, “I wanted to help
patients who needed orthopaedic care,
but I’m not a physician. I thought, ‘What
can I do? What are my talents and how
can I use them? I knew I didn’t have the
skill set to do medical missions myself,
but I had access to people who could.”
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Molly Shumate,
Dr. Sean Calloway,
and Daniel Shumate
So with that motivation, and to honor his
wife, Daniel founded the Molly Shumate
Community Service Scholarship three
years ago to sponsor medical missions
nationally and internationally as a way
to provide excellent orthopaedic care
to patients in need - here and across
the globe.
Three orthopaedic surgery residents
in training at the Campbell Foundation
have now gone on medical mission
trips, thanks to the scholarship - to
Nicaragua, Guatemala and Honduras.
This past May, Dr. Eric Bowman, who is a
4th year resident in training, traveled to
Tegucigalpa, Honduras, along with a team
of 39 other medical professionals. While
there, Bowman and the team performed
60 orthopaedic surgeries, including
complex hand surgeries, total hips and
total knees. In addition, the team saw
approximately 700 patients during their
time in the clinic there.
“What struck me most about the patients
we saw and treated in Honduras,” says
Bowman, “was their gratitude. They were
thankful even if we had to tell them that
we wouldn’t be able to do their surgery
this year, on this trip. I learned that the
people of Honduras have many needs, but
they are not needy. It was enlightening
to see how orthopaedics is done outside
of our country. This left an incredible
impression on me, and I will definitely
return to help more people. There is so
much more that we can do.”
So, what started at a business luncheon
has grown into a robust medical mission.
The Shumates are continuing their
support, and have just selected Dr. Sean
Calloway, a member of the Campbell
Residency Class of 2016, as this year’s
scholarship winner. Calloway will serve
for two weeks in early 2016 at the
Kilimanjaro Christian Medical Clinic in
Tanzania, in conjunction with Health
Volunteers Overseas.
Calloway and his team will need vital
medical supplies for this mission —
including surgical supplies and implants,
but also general clinic supplies like gloves
and gowns - to serve the population in
need of orthopaedic care.
You can help equip this year’s team for
service. Consider a gift to the Campbell
Foundation in honor of a doctor or
therapist who helped you walk again,
without pain - or, you might wish to
donate in honor of a loved one. Either
way, the more you give, the more you will
help through your gift.
Go online to campbell-foundation.org to
donate, or call the Development Office at
(901) 759-5490 today!
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
Campbell Foundation Foot
Fellow David Ruta, MD, along
with Resident Catherine Olinger,
MD providing free foot care to
adults served by the Memphis
Union Mission.
Hand Surgeon Returns
SO L E S FOR S OULS
Campbell Clinic Employee Angel Agus,
along with Brittany Bridgers and Tylar
Agus along with shoes, socks and fresh
water for the men and women of the
Memphis Union Mission.
TO MEMPHIS
and Joins Campbell Clinic Team in Southaven
Every single day of the year, Campbell Clinic surgeons and residents provide
orthopaedic care at every hospital in downtown Memphis - the V.A. hospital,
Methodist University, Le Bonheur Children’s and Regional One - to every patient
who enters those hospitals. But, there are hundreds of people living on the street —
homeless — who might slip through the cracks.
That’s part of the reason that every year, around Thanksgiving, a small team of
surgeons, residents and staff from Campbell Clinic and Campbell Foundation quietly
serve people in great need through a small outreach called “From Our Hearts to Your
Soles.” During this event, Campbell provides free foot care to men and women being
served by the Memphis Union Mission. The compassionate care includes providing
those served with a new pair of clean, dry socks and new shoes, provided by
RedWing Boots, our partner in the event.
“It’s a wonderful reminder during the holiday season for us to count our blessings and
share our bounty with those less fortunate,” says Dr. David Richardson, Campbell Foot
& Ankle Surgeon. “In this small way, we can help, and it teaches our residents to give
back, as well.”
You can help a person in need with your gift to the Campbell Foundation today. You
may donate online through our secure website, campbell-foundation.org, or call the
Development Office at (901) 759-5490.
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Campbell Clinic welcomed a new
physician to the staff late this
summer. Dr. Norfleet B. Thompson
joined Campbell Clinic as the group’s
47th physician in August. He serves as a
hand surgeon and is based in the clinic’s
Southaven office, serving residents of
Desoto County and much of
North Mississippi.
Dr. Thompson is no stranger to Memphis
or the state of Tennessee. He earned
an undergraduate degree at Vanderbilt
University in Nashville in 2003 and
graduated from medical school at The
University of Tennessee’s College of
Medicine in Memphis in 2009.
Thompson completed his residency at
UT-Campbell Clinic in 2014 before a oneyear hand fellowship at The University
of New Mexico. We are proud to add Dr.
Thompson to the Campbell Clinic family!
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RECENT PUBLICATIONS FROM THE CAMPBELL FOUNDATION
Alexander T, Azar FM, Mauck B, Smith R, Throckmorton
TW. The effect of humeral rotation on elbow range-ofmotion measurements. Am J Orthop (Belle Mead NJ).
2015 Feb;44(2):73-6. PMID: 25658075.
Amini MH, Sykes JB, Olson ST, Smith RA, Mauck BM,
Azar FM, Throckmorton TW. Reliability testing of two
classification systems for osteoarthritis and posttraumatic arthritis of the elbow. J Shoulder Elbow Surg.
2015 Mar;24(3):353-7. doi: 10.1016/j.jse.2014.10.015. Epub
2014 Dec 23. PMID: 25541343.
Amini MH, Azar FM, Wilson BR, Smith RA, Mauck BM,
Throckmorton TW. Comparison of Outcomes & Costs
of Tension-Band & Plate Osteosynthesis in Transverse
Olecranon Fractures: A Matched Cohort Study. Am J
Orthop. 2015;44(7):E211-E215 July 2015 Volume 44 No. 7.
Bettin CC, Gower K, McCormick K, Wan JY,
Ishikawa SN, Richardson DR, Murphy GA. Cigarette
smoking increases complication rate in forefoot
surgery. Foot Ankle Int. 2015 May;36(5):488-93. doi:
10.1177/1071100714565785. Epub 2015 Jan 12. PMID:
25583954.
Biggers MD, Bert TM, Moisan A, Spence DD, Warner WC
Jr, Beaty JH, Sawyer JR, MD, Kelly DM. Fracture of the
Medial Humeral Epicondyle in Children: A Comparison
of Operative and Nonoperative Management. JSOA
2015-24-3-F8.
Biggers MD, Mascioli AA, Mauck BM, Azar FM, Smith
RA, Throckmorton TW. Analysis of mechanical failures
after anatomic acromioclavicular joint reconstruction.
Current Orthopaedic Practice. Sept/Oct 2015, 26(5):
526-529. doi: 10.1097/BCO.0000000000000269
Bonnaig NS, Throckmorton TW. Elbow arthritis: scope,
open, or total elbow replacement? Current Orthopaedic
Practice. 26(2):126-129, March/April 2015. doi: 10.1097/
BCO.0000000000000208.
Bonnaig NS, Throckmorton TQ. Repair and
reconstruction of the lateral ulnar collateral ligament.
Instr Course Lect. 2015;64:243-6. PMID: 25745910.
Chao J, Choi JH, Grear BJ, Tenenbaum S, Bariteau JT,
Brodsky JW. Early radiographic and clinical results of
Salto total ankle arthroplasty as a fixed-bearing device.
Foot Ankle Surg. 2015 Jun;21(2):91-6. doi: 10.1016/j.
fas.2014.09.012. Epub 2014 Oct 8. PMID: 25937407.
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Cho H, Holt DC 3rd, Smith R, Kim SJ, Gardocki RJ,
Hasty KA. The Effects of Platelet-Rich Plasma on
Halting the Progression in Porcine Intervertebral Disc
Degeneration. Artif Organs. 2015 Jul 6. doi: 10.1111/
aor.12530. [Epub ahead of print] PMID: 26147759
Cho H, Pinkhassik E, David V, Stuart JM, Hasty KA.
Detection of early cartilage damage using targeted
nanosomes in a post-traumatic osteoarthritis mouse
model. Nanomedicine. 2015 May;11(4):939-46. doi:
10.1016/j.nano.2015.01.011. Epub 2015 Feb 11.
Cho H, Walker A, Williams J, Hasty KA. Study of
osteoarthritis treatment with anti-inflammatory drugs:
cyclooxygenase-2 inhibitor and steroids. Biomed Res
Int. 2015; 2015:595273. doi: 10.1155/2015/595273. Epub
2015 Apr 27. PMID: 26000299 [PubMed - in process]
PMCID: PMC4427003
Chung C, DiAngelo DJ. Scoliosis Analog Model for
the Evaluation of Bracing Technology. Journal of the
Mississippi Academy of Sciences. 2015, April 60(Suppl.
Issue 1), 187-192.
DiAngelo DJ, Simmons J, Wido D. Robotized Method
for Comparative Testing of Back Support Device.
Journal of the Mississippi Academy of Sciences. 2015,
April 60(Suppl. Issue 1), 179-186.
DiAngelo DJ, Sims J. Towards the Design of a
Distractive and Mobility-Enabling Back Support Device.
Journal of the Mississippi Academy of Science, 2015,
April 60(Suppl. Issue 1), 193-200.
Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum
SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun
J, Daraei P, Christofk HR, Hewitt SC, Korach KS,
Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener
AL. Estrogen receptor (ER)α-regulated lipocalin
2 expression in adipose tissue links obesity with
breast cancer progression. J Biol Chem. 2015 Feb
27;290(9):5566-81. doi: 10.1074/jbc.M114.606459. Epub
2014 Dec 2. PMID: 25468909 [PubMed - indexed for
MEDLINE] PMCID: PMC4342471 [Available on 201602-27]
Gilbert SR, MacLennan PA, Backstrom I, Creek
A, Sawyer JR. Altered lower extremity fracture
characteristics in obese pediatric trauma patients.
Orthop Trauma. 2015 Jan;29(1):e12-7. doi: 10.1097/
BOT.0000000000000132. PMID: 24740109 [PubMed
- in process] PMCID: PMC4198524 [Available on 201601-01]
Glotzbecker MP, Shore BJ, Fletcher ND, Larson
AN, Hydorn CR, Sawyer JR; Practice Management
Committee of the Pediatric Orthopaedic Society of
North America. Early Career Experience of Pediatric
Orthopaedic Fellows: What to Expect and Need for
Their Services. J Pediatr Orthop. 2015 Mar 3. [Epub
ahead of print] PMID: 25851674.
Habashy A, Murphy RF, Williams KD. A lumbar discal
cyst in a professional athlete. Current Orthopaedic
Practice. 26(2):201-203, March/April 2015. doi: 10.1097/
BCO.0000000000000205.
Hicks A, Nord K, Powell M, Slominski A, Cho H, Hasty
KA. Unique Vitamin D Analogue for the Inhibition of
NFkB in Treatment of Osteoarthritis. American Medical
Student Research Journal. 2015, 1(2), 106-114
Huffman KD, Sanford BA, Zucker-Levin AR, Williams
JL, Mihalko WM. Increased hip abduction in high body
mass index subjects during sit-to-stand. Gait Posture.
2015 Feb;41(2):640-5. doi: 10.1016/j.gaitpost.2015.01.014.
Epub 2015 Jan 21. PMID: 25655834.
Hyman JE, Trupia EP, Wright ML, Matsumoto H, Jo CH,
Mulpuri K, Joseph B, Kim HK; (Kelly DM of) International
Perthes Study Group Members. Interobserver and
intraobserver reliability of the modified Waldenström
classification system for staging of Legg-Calvé-Perthes
disease. J Bone Joint Surg Am. 2015 Apr 15;97(8):64350. doi: 10.2106/JBJS.N.00887. PMID: 25878308.
Jevsevar DS, Cummins DS, Azar FM, Parsley BS,
Fehring TK, Lachiewicz PF, Watters WC 3rd. One size
does not fit all: involve orthopaedic implant patients
in deciding whether to use prophylactic antibiotics
with dental procedures. J Am Acad Orthop Surg. 2015
Mar;23(3):141-2. doi: 10.5435/JAAOS-D-15-00045. Epub
2015 Feb 9. PMID: 25667402.
Kavanaugh TE, Werfel TA, Cho H, Hasty KA, Duvall CL.
Particle-based technologies for osteoarthritis detection
and therapy. Drug Deliv Transl Res. 2015 May 20. [Epub
ahead of print] PMID: 25990835 [PubMed - as supplied
by publisher]
Kelly DM, Spence, DD. Pediatric Orthopaedics. Current
Orthopaedic Practice: Special Focus. September/
October 2015 - Volume 26 - Issue 5 - p 451. doi: 10.1097/
BCO.0000000000000288
Lyons MM, Sheth NP, Williams NN, Gurubhagavatula
I, Mihalko WM. Obesity, orthopaedics, and outcomes.
J Am Acad Orthop Surg. 2015 Apr;23(4):210-2. doi:
10.5435/JAAOS-D-15-00098. PMID: 25808684.
Manning BT, Lewis N, Tzeng TH, Saleh JK, Potty AG,
Dennis DA, Mihalko WM, Goodman SB, Saleh KJ.
Diagnosis and Management of Extra-articular Causes
of Pain After Total Knee Arthroplasty. Instr Course Lect.
2015;64:381-8. PMID: 25745922.
Martin A, Xiong J, Koromila T, Ji JS, Chang S, Song
YS, Miller JL, Han CY, Kostenuik P, Krum SA, Chimge
NO, Gabet Y, Frenkel B. Estrogens antagonize RUNX2mediated osteoblast-driven osteoclastogenesis through
regulating RANKL membrane association. Bone. 2015
Jun;75:96-104. doi: 10.1016/j.bone.2015.02.007. Epub
2015 Feb 17. PMID: 25701138 [PubMed - in process]
PMCID: PMC4387095 [Available on 2016-06-01]
McCabe MP, Weinlein JC, Perez EA, Russell TA. Use of
blocking screws in intramedullary nailing of long-bone
fractures. Current Orthopaedic Practice. January/
February 2015 - Volume 26 - Issue 1 - p 56–63. doi:
10.1097/BCO.0000000000000192.
Mihalko WM. How Do I Get What I Need? Navigating
the FDA’s Custom, Compassionate Use, and HDE
Pathways for Medical Devices and Implants. J
Arthroplasty. 2015 Jun;30(6):919-22. doi: 10.1016/j.
arth.2015.01.025. Epub 2015 Jan 23. PMID: 25690754.
Mihalko WM, Assaf D, Sungu M. Reproducing the
hip center with a femoral neck-retaining implant.
Orthopedics. 2015 Mar;38(3 Suppl):S21-6. doi:
10.3928/01477447-20150215-52. PMID: 25826628.
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C A M P B E L L I N M O T I O N | FA L L 2 0 1 5
RECENT PUBLICATIONS FROM THE CAMPBELL FOUNDATION
Mihalko WM, Whiteside LA. Stem pain after cementless
revision total knee arthroplasty. J Surg Orthop Adv.
2015 Summer;24(2):137-9. PMID: 25988697.
Mihalko WM, Woodard EL, Hebert CT, Crockarell JR,
Williams JL. Biomechanical validation of medial piecrusting for soft-tissue balancing in knee arthroplasty.
J Arthroplasty. 2015 Feb;30(2):296-9. doi: 10.1016/j.
arth.2014.09.005. Epub 2014 Sep 16. PMID: 25288524.
Miller DJ, Throckmorton TW, Azar FM, Beaty JH, Canale
ST, Richardson DR. Business and Practice Management
Knowledge Deficiencies in Graduating Orthopedic
Residents. Am J Orthop (Belle Mead NJ). 2015
Oct;44(10):E373-8.
Mitchelson AJ, Wilson CJ, Mihalko WM, Grupp TM,
Manning BT, Dennis DA, Goodman SB, Tzeng TH,
Vasdev S, Saleh KJ. Biomaterial hypersensitivity: is it
real? Supportive evidence and approach considerations
for metal allergic patients following total knee
arthroplasty. Biomed Res Int. 2015;2015:137287. doi:
10.1155/2015/137287. Epub 2015 Mar 25. Review. PMID:
25883940. 2014 Sept. Article ID 137287
Murphy RF, Azar FM, Mauck BM, Smith RA,
Throckmorton TW. Accuracy testing of four
physical examination maneuvers for detecting
lateral epicondylitis. Current Orthopaedic Practice.
26(4):367-370, July/August 2015. doi: 10.1097/
BCO.0000000000000243.
Murphy RF, Cibulas AM, Sawyer JR, Spence DD, Kelly
DM. Levels of Evidence in the Journal of Pediatric
Orthopaedics: Update and Comparison to the Journal
of Bone and Joint Surgery. J Pediatr Orthop. October/
November 2015 - Volume 35 - Issue 7 - p 779–781 doi:
10.1097/BPO.0000000000000362
Murphy RF, Davidson AR, Kelly DM, Warner WC Jr,
Sawyer JR. Subaxial cervical spine injuries in children
and adolescents. J Pediatr Orthop. 2015 Mar;35(2):1369. doi: 10.1097/BPO.0000000000000341. PMID:
25379826.
Murphy RF, Kelly DM, Moisan A, Thompson NB, Warner
WC Jr, Beaty JH, Sawyer JR. Transverse fractures of the
femoral shaft are a better predictor of nonaccidental
trauma in young children than spiral fractures are.
J Bone Joint Surg Am. 2015 Jan 21;97(2):106-11. doi:
10.2106/JBJS.N.00664. PMID: 25609436.
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Murphy RF, Moisan A, Kelly DM, Warner WC Jr, Jones
TL, Sawyer JR. Use of Vertical Expandable Prosthetic
Titanium Rib (VEPTR) in the Treatment of Congenital
Scoliosis Without Fused Ribs. J Pediatr Orthop. 2015
Apr 13. [Epub ahead of print] PMID: 25887832.
Naranje SM, Erali RA, Warner WC Jr, Sawyer JR, Kelly
DM. Epidemiology of Pediatric Fractures Presenting
to Emergency Departments in the United States. J
Pediatr Orthop. 2015 Jul 14. [Epub ahead of print] PMID:
26177059
Naranje SM, Gilbert SR, Stewart MG, Rush JK, Bleakney
CA, McKay JE, Warner WC Jr, Kelly DM, Sawyer
JR. Gunshot-associated Fractures in Children and
Adolescents Treated at Two Level 1 Pediatric Trauma
Centers. J Pediatr Orthop. 2015 Jan 28. [Epub ahead of
print] PMID: 25633608.
Naranje SM, Stewart MG, Kelly DM, Jones TL, Spence
DD, Warner WC Jr, Beaty JH, Sawyer JR. Changes in
the Treatment of Pediatric Femoral Fractures: 15-Year
Trends From United States Kids’ Inpatient Database
(KID) 1997 to 2012. J Pediatr Orthop. 2015 Aug 28.
[Epub ahead of print] PMID: 26327403
Potty AG, Tzeng TH, Sams JD, Lovell ME, Mihalko
WM, Thompson KM, Parke J, Manning BT, Dennis DA,
Goodman SB, Saleh KJ. Diagnosis and Management
of Intra-articular Causes of Pain After Total Knee
Arthroplasty. Instr Course Lect. 2015;64:389-401. PMID:
25745923.
Pretell-Mazzini J, Kelly DM, Sawyer JR, Esteban EM,
Spence DD, Warner WC Jr, Beaty JH. Outcomes and
Complications of Tibial Tubercle Fractures in Pediatric
Patients: A Systematic Review of the Literature. J
Pediatr Orthop. 2015 Apr 10. [Epub ahead of print]
PMID: 25887827.
Ran L, Yu Q, Zhang S, Xiong F, Cheng J, Yang P, Xu JF,
Nie H, Zhong Q, Yang X, Yang F, Gong Q, Kuczma M,
Kraj P, Gu W, Ren BX, Wang CY. Cx3cr1 deficiency in
mice attenuates hepatic granuloma formation during
acute schistosomiasis by enhancing the M2-type
polarization of macrophages. Dis Model Mech. 2015 Jul
1;8(7):691-700. doi: 10.1242/dmm.018242. Epub 2015
Apr 21. PMID: 26035381 [PubMed - in process] PMCID:
PMC4486856
Rhodes L, Nash C, Moisan A, Scott DC, Barkoh K,
Warner WC Jr, Sawyer JR, Kelly DM. Does preoperative
orientation and education alleviate anxiety in posterior
spinal fusion patients? A prospective, randomized
study. Pediatr Orthop. 2015 Apr-May;35(3):276-9. doi:
10.1097/BPO.0000000000000260. PMID: 25036417.
Shore BJ, DiMauro JP, Spence DD, Miller PE,
Glotzbecker MP, Spencer S, Hedequist D. Uniplanar
Versus Taylor Spatial Frame External Fixation For
Pediatric Diaphyseal Tibia Fractures: A Comparison of
Cost and Complications. J Pediatr Orthop. 2015 Jun 17.
[Epub ahead of print] PMID: 26090976.
Roberson TA, Azar FM, Miller RH III, Throckmorton
TW. Predictors of Post-Operative Pain and Narcotic
Use after Primary Arthroscopic Rotator Cuff Repair. J
Shoulder Elbow Surg. Vol. 24, Issue 4, e106. Published
in issue: April 2015. doi: http://dx.doi.org/10.1016/j.
jse.2014.11.003
Spence D, DiMauro JP, Miller PE, Glotzbecker MP,
Hedequist DJ, Shore BJ. Osteonecrosis After Femoral
Neck Fractures in Children and Adolescents: Analysis
of Risk Factors. J Pediatr Orthop. 2015 Feb 26. [Epub
ahead of print] PMID: 25730381.
Roberson TA, Jew ND, Azar FM, Mauck BM,
Dockery JD, Throckmorton TW. Cervical radiculitis
presenting as shoulder pain: frequency and results of
multidisciplinary care. Current Orthopaedic Practice.
Sept/Oct 2015, Vol 26(5), p. 521-525 doi: 10.1097/
BCO.0000000000000270
Rush JK, Astur N, Scott S, Kelly DM, Sawyer JR,
Warner WC Jr. Use of magnetic resonance imaging
in the evaluation of spondylolysis. J Pediatr
Orthop. 2015 Apr-May;35(3):271-5. doi: 10.1097/
BPO.0000000000000244. PMID: 24978120.
Saleh KJ, Kurdi AJ, El-Othmani MM, Voss BA, Tzeng TH,
Saleh J, Lane JM, Mihalko WM. Perioperative Treatment
of Patients with Rheumatoid Arthritis. J Am Acad
Orthop Surg. 2015 Sep;23(9):e38-48. doi: 10.5435/
JAAOS-D-15-00014. Epub 2015 Aug 13. PMID: 26271759
Shanker S, Paulson A, Edenberg HJ, Peak A, Perera
A, Alekseyev YO, Beckloff N, Bivens NJ, Donnelly R,
Gillaspy AF, Grove D, Gu W, Jafari N, Kerley-Hamilton
JS, Lyons RH, Tepper C, Nicolet CM. Evaluation of
commercially available RNA amplification kits for RNA
sequencing using very low input amounts of total
RNA. J Biomol Tech. 2015 Apr;26(1):4-18. doi: 10.7171/
jbt.15-2601-001. PMID: 25649271 [PubMed - in process]
PMCID: PMC4310221
Stephens BF, Hebert CT, Azar FM, Mihalko WM,
Throckmorton TW. Optimal baseplate rotational
alignment for locking-screw fixation in reverse total
shoulder arthroplasty: a three-dimensional computeraided design study. J Shoulder Elbow Surg. 2015
Mar 26. pii: S1058-2746(15)00050-6. doi: 10.1016/j.
jse.2015.01.012. [Epub ahead of print] PMID: 25819730.
Tasaki A, Morita W, Yamakawa A, Nozaki T, Kuroda
E, Hoshikawa Y, Phillips BB. Combined Arthroscopic
Bankart Repair and Coracoid Process Transfer to
Anterior Glenoid for Shoulder Dislocation in Rugby
Players: Evaluation Based on Ability to Perform SportSpecific Movements Effectively. Arthroscopy. 2015
Apr 25. pii: S0749-8063(15)00222-4. doi: 10.1016/j.
arthro.2015.03.013. [Epub ahead of print]
Tauchi R, Tsuji T, Cahill PJ, Flynn JM, Flynn JM,
Glotzbecker M, El-Hawary R, Heflin JA, Imagama S,
Joshi AP, Nohara A, Ramirez N, Roye DP Jr, Saito T,
Sawyer JR, Smith JT, Kawakami N. Reliability analysis of
Cobb angle measurements of congenital scoliosis using
X-ray and 3D-CT images. Eur J Orthop Surg Traumatol.
2015 Sep 16. [Epub ahead of print] PMID: 26377663
Throckmorton TW, Gulotta LV, Bonnarens FO,
Wright SA, Hartzell JL, Rozzi WB, Hurst JM, Frostick
SP, Sperling JW. Patient-specific targeting guides
compared with traditional instrumentation for glenoid
component placement in shoulder arthroplasty: a
multi-surgeon study in 70 arthritic cadaver specimens.
J Shoulder Elbow Surg. 2015 Jun;24(6):965-71. doi:
10.1016/j.jse.2014.10.013. Epub 2014 Dec 19. PMID:
25535020.
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RECENT PUBLICATIONS FROM THE CAMPBELL FOUNDATION
Torosyan Y, Kurtz SM, Mihalko WM, Marinac-Dabic
D, Rimnac CM. Editorial: arthroplasty devices:
registries and beyond. Clin Orthop Relat Res. 2015
Feb;473(2):403-5. doi: 10.1007/s11999-014-4061-4. Epub
2014 Nov 25. PMID: 25421957.
Voss B, Kurdi A, Skopec A, Saleh J, El-Othmani
MM, Lane JM, Mihalko WM, Saleh KJ. Renal and
Gastrointestinal Considerations in Joint Replacement
Surgery. J Nat Sci. 2015 Feb 1;1(2):e46. PMID: 25811046.
Wang L, Jiao Y, Sun S, Jarrett HW, Sun D, Gu W. Gene
network of a phosphoglycerate mutase in muscle
wasting in mice. Cell Biol Int. 2015 Jun;39(6):666-77. doi:
10.1002/cbin.10437. Epub 2015 Mar 2. PMID: 25644094
[PubMed - in process]
Weinlein JC, Deaderick S, Murphy RF. Morbid obesity
increases the risk for systemic complications in patients
with femoral shaft fractures. J Orthop Trauma. 2015
Mar;29(3):e91-5. doi: 10.1097/BOT.0000000000000167.
Epub 2014 Jun. PMID: 24978946.
Wright J, Potts C, Smyth MP, Ferrara L, Sperling JW,
Throckmorton TW. A quantitative analysis of the effect
of baseplate and glenosphere position on deltoid
lengthening in reverse total shoulder arthroplasty.
Int J Shoulder Surg. 2015 Apr-Jun;9(2):33-7. doi:
10.4103/0973-6042.154752. PMID: 25937711.
Zhang Y, Huang J, Jiao Y, David V, Kocak M,
Roan E, DiAngelo DJ, Lu L, Hasty KA, Gu W.
BXD recombinant inbred strains and femur-tibia
correlation. ScientificWorldJournal. 2015;2015:728278.
doi: 10.1155/2015/728278. Epub 2015 Feb 25. Bone
morphology in 46 PMID: 25811045 [PubMed - in
process] PMCID: PMC4355808
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