The Savin Center
Transcription
The Savin Center
SAVIN — CENTER Ronald Savin, MEDICAL & COSMETIC DERMATOLOGY I CLINICAL RESEARCH MD 203.865.6143 [email protected] SavinCenter.com 134 Park Street New Haven, CT 06511 Ronald C. Savin, M.D. Summary: • Dermatology and Dermatologic Surgery private practice physician since 1965. • Independent investigator -- Clinical Research Studies of new dermatologic investigative drugs, existing drugs, and other dermatologic products. • Author of numerous scientific and consumer-oriented articles. Education: 1968 Diplomat - American Board of Dermatology 1964-1965 Post Graduate Research Fellow in Dermatology, Yale University School of Medicine 1964-1965 Chief Resident, Dermatology, Yale-New Haven Hospital 1962-1964 Assistant Resident, Dermatology, Yale-New Haven Hospital 1961-1962 Medical Intern, University of Miami, Jackson Memorial Hospital 1957-1961 University of Florida, M.D. 1953-1957 Yale University, A.B., English Literature Teaching and Research Positions: 1984-Present Clinical Professor of Dermatology, Yale University School of Medicine 1980-1984 Associate Clinical Professor of Dermatology, Yale University School of Medicine 1977-1980 Assistant Clinical Professor of Dermatology, Yale University School of Medicine 1965-1977 Clinical Instructor in Dermatology, Yale University School of Medicine. Active participation in the clinical evaluation of numerous investigational dermatologic drugs. RONALD SAVIN, MD BOARD CERTIFIED IN DERMATOLOGY, CLINICAL PROFESSOR DERMATOLOGY, YALE UNIVERSITY - FELLOW, AMERICAN ACADEMY OF DERMATOLOGY AMERICAN SOCIETY FOR DERMATOLOGIC SURGERY, SOCIETY OF INVESTIGATIVE DERMATOLOGY, HAIR RESEARCH SOCIETY 1964-1965 Post Graduate Research Fellow in Dermatology, Yale University School of Medicine. Research included numerous clinical drug investigations with topical steroids, anti-viral & anti-fungal agents, etc.,as well as investigation into skin darkening effect of pituitary extracts in animals. 1959-1961 Florida Tuberculosis Association Research Fellow, University of Florida College of Medicine. Studied pathogenicity of commensal oral flora. Institutional Affiliations: Clinical Professor of Dermatology, Yale University School of Medicine Board of Permanent Officers, Yale University School of Medicine Attending Physician, Yale-New Haven Hospital Attending Physician, St. Raphael Hospital, New Haven Professional Organizations: Consultant, Connecticut State Medical Society, Section of Dermatology, 1979 to Present. American Medical Association American Academy of Dermatology Reviewer for the American Academy of Dermatology, 1988 to Present Licensure: Connecticut State Medical License #010966 New York State Medical License # 264967-1 Former Affiliations: Secretary, Assn. of Clinical Attendings in Dermatology, Yale-New Haven Hospital, 1971 to 1994. Committee on HMOs, American Academy of Dermatology, 1977 to 1993. Member, State Issues Task Force, American Academy of Dermatology, 1993 to 1995. Advisory Board, American Academy of Dermatology, 1977 to 1985. Board of Directors, Hair Research Society, 1990 - 1993. President, Section of Dermatology, Connecticut State Medical Society, 1973 - 1974. Medical Board, Yale-New Haven Hospital, 1976 - 1978. Council Member, Section of Dermatology, Connecticut State Medical Society, 1974 - 1978. Chairman, Executive Advisory Board Tower I - Housing for the Elderly, 1974 - 1975. Medical Director, Camp Laurelwood (Children's Agency Camp), 1970 - 1975. Ronald C. Sevin, M.D. 2 Last Updated 03/03/14 Publications: "Global photographic assessment of men aged 18 to 60 years with male pattern hair loss receiving finasteride 1 mg or placebo." Olsen, EA; Whiting, DA; Savin, RC; et al. JAAD 67, 3:2012 "Evaluation of the Efficacy and Safety of Clobetasol Propionate Spray in the Treatment of Plaque-Type Psoriasis." Jarratt, MT; Clark, SD; Savin, RC; et al. CUTIS 2006; 78:348-54. "The safety and efficacy of sertaconazolw nitrate cream 2% for tinea pedis." Jorizzo, J; Savin, R. CUTIS 2006; 78: 268-274. "Effect of a single course of isotretinoin therapy on bone mineral density in adolescent patients with severe, recalcitrant, nodular acne." DiGiovanni, J.; Savin, R.; et al. JAAD 51, 5:2004 " A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss." Lucky A.; Ditre C.; et al. JAAD 50, 4:2004 "A systemic type 1 5 alpha reductase inhibitor is ineffective in the treatment of acne vulgaris." Leyden J.; Bergfeld W.;et al. JAAD 50, 3:2004 "Ciclipirox gel in the treatment of patients with interdifital tinea pedis" Aly R.; Fisher G.; et al. International Journal of Dermatology. 2003; 42: 29-35 "Ciclipirox gel for seborrheic dermatitis of the scalp" Aly R.; Katz I.; et al. International Journal of Dermatology. 2003; 42: 19-22 "Efficacy and tolerability of finasteride 1mg in men aged 41 to 60 years with male pattern hair loss." Whiting, D., Olsen, E., Savin, R., et al. European Journal of Dermatology. 2003;13:150-160. "Randomized trial evaluating a new 0.5% Fluorouracil formulation demonstrates efficacy after 1, 2 or 4 week treatment in patients with actinic keratosis. " Jorizzo, J., Stewart D., Savin, R., et al. Cutis. 2002; 70: 335-39. "A randomized trial of the efficacy of a new micronized formulation versus a standard formulation of isotretinoin in patients with severe recalcitrant nodular acne." Strauss, J., Leyden, J., Savin, R., et al. J Amer Acad Derm. 2001; 45:187-95. "Efficacy and safety of terbinafine 1% solution in the treatment of interdigital tinea pedis and tines corporis or tinea cruris." Lebwohl, M., Elewski, B., Eisen, D., Savin, R. Cutis. 2001;67:261-266. "Lack of efficacy of finasteride in postmeopausal women ith androgenic alopecia." Price, V., Roberts, J., Hordinsky, M., Savin, R., Bergfled, W., Fiedler, V., Lucky, A., Whiting, D., Pappas, F., Culbertson, J., Kotey, P., Meehan, A., Waldstreicher, J. J Amer Acad Derm. 2000. 43:5 768-776. "Clinical dose ranging studies with finasteride, a type 2 5a-reductase inhibitor, in men with male pattern hair loss." Roberts, JL., Fiedler, V., Imperato-McGinley, J., Whiting, D., Olsen, E., Shupack, J., Savin, RC. J Amer Acad Derm. 1999. 41:4 555-563. Ronald C. Savin, M.D. 3 Last Updated 03/03/14 "Split-face comparision of tretinoin cream 0.025% and adapalene gel 0.1% in the treatment of acne vulgaris." Savin, R., Berger R. Cosmetic Dermatology. 1999; 12:2 29-32. "Severe urticarial reaction to diphenylcyclopenone therapy for alopecia areata." Alam, M., Gross, E., Savin, R. J Amer Acad Derm. 1999; 40:1 110-112. "Prevalence of male pattern baldness in 18-49 year old men." Rhodes T., Girman, C., Savin R., et al. Dermatologic Surgery 1998; 24:12 1330-1332. "Ketoconazole 2% shampoo in the treatment of tinea versicolor: A multicenter, randomized, doubleblind, placebo-controlled trial." Lange, D., Richards, H., Guarnieri, J., Humeniuk, J., Savin, R., et al. J Amer Acad Derm. 1998; 39:6. 944-950. "Clinical dose ranging studies with finasteride, a type 2 5a-reductase inhibitor, in men with male pattern hair loss." Roberts, J. for the Finasteride Male Pattern Hair Loss Study Group. Archives of Dermatology 1998. (in press) "Finasteride in the treatment of adrogenetic alopecia (male pattern hair loss)." Kaufman, K., Olsen, E., Whiting, D., Savin, R., et al. J Amer Acad Derm. 1998:39:4 578-589. "Once-weekly fluconazole (150, 300, or 450 mg) in the treatment of distal subungual onychomycosis of the toenail." Scher, R., Breneman, D., Rich, P., Savin, R., et al. J Amer Acad Derm. 1998; 38: S77S86. "Once-weekly fluconazole (150, 300, or 450 mg) in the treatment of distal subungual onychomycosis of the fingernail." Drake, L., et al. J Amer Acad Derm. 1998; 38: S87-S94. "Pharmacokinetics of three doses of once-weekly fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the toenail." Rich, P., Scher, R., Breneman, D., Savin, R., et al. J Amer Acad Derm. 1998; 38: S103-S109. "Pharmacokinetics of three doses of once-weekly fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail." Savin R., Drake, L., Babel D., et al. J Amer Acad Derm. 1998; 38: S110-S116. "The effects of finasteride in postmenopausal women with androgenetic alopecia." Roberts, J., Hordinsky, M., Olsen, E., Savin R., et al. Poster Exhibit #103. Hair Workshop. Brussels 1998. "Oral terbinafine in the treatment of toenail onychomycosis: North American multicenter trial." Drake, L., Shear, N., Arlette, J., Savin, R., et al. J Amer Acad Derm. 1997; 37: 740-5. "Sustained improvement in photodamaged skin with reduced tretinoin emollient cream treatment regimen: Effect of once-weekly and three-times-weekly applications." Olsen, E, Katz, HI, Levine, N, Nigra, T., Pochi, P., Savin, RC, et al. J Amer Acad Derm. 1997; 37: 227-230. "Tretinoin emollient cream for photodamaged skin: Results of 48-week, multicenter, double-blind studies." Olsen, E, Katz, HI, Levine, N, Nigra, T., Pochi, P., Savin, RC, et al. J Amer Acad Derm. 1997; 37: 217-226. "One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: A multicenter, double-blind trial." Savin, RC., De Villez, R., Elewski, B., et al. J Amer Acad Derm. 1997; 36:S15-19. Ronald C. Sevin, M.D. 4 Last Updated 03/03/14 "Efficacy and safety of terbinafine 1% solution in the treatment of pityriasis versicolor. A randomized, double-blind, multicenter , prospective study." Savin, RC., Butterwick, K., Eisen, D., Elewski, B., et al. Poster Amer Acad Derm. San Francisco 1997. "One week treatment of tinea pedis with butenafine: HCI 1%." Savin, RC., Lucky, A., Brennan, B. Poster Amer Acad Derm. San Francisco 1997. "Efficacy and safety of Elocon cream versus Westcort cream in pediatric patients with atopic dermatitis unresponsive to hydrocortisone." Lebwohl M., Lane A., Savin R., et al. Poster Amer Acad Derm. San Francisco 1997. "Aggressive Acne Treatment: As Simple As One, Two, Three?" Savin RC, Donofrio LM. The Physician and Sportsmedicine. 1996; Vol 24. No 9: 41-51. "Diagnosis and treatment of tinea versicolor." Savin, RC. Journ of Family Practice. 1996; 43:v2: 127-32. "Terbinafine in the treatment of fingernail onychomycosis: A multicenter trial." Savin R.C., et al. Poster. Amer. Acad. Derm. New Orleans 1995. "Oral terbinafine (Lamisil) in the treatment of toenail onychomycosis: North American multicenter study." Drake L.A., Arlette J.P., Elewski B., Savin R., et al. Poster. Amer. Acad. Derm. New Orleans 1995. "Diflurasone diacetate cream in an optimized vehicle versus flucinonide cream for the treatment of psoriasis." Journal of Dermatological Treatment. 1995:6; 219-222. "Long-Term outcome of patients with interdigital tinea pedis treated with terbinafine or clotrimazole." Elewski B., Bergstresser P., Hanifin J., Lesher J., Savin R., et al. J Am Acad Dermatol. 1995; 32:2902. "Reproducibility of Global Photographic Assessment of Patients with Male Pattern Baldness in a Clinical Trial With Finasteride." Kaufman K., Binkowitz B., Savin R., Canfield D. Poster 628. Soc. Inv. Derm. Chicago 1995. "Androgenetic Alopecia in the Female: Treatment with 2% Topical Minoxidil Solution", DeVillez, R.L., Jacobs, J.P., Szpunar, C.A., and Warner, M.L.. (R.C. Savin, Principal Investigator), Archives of Dermatology 1994; 130: 303-307. "A 12-month pilot clinical study of the effects of finasteride on men with male pattern baldness." Kaufman, K; DeVillez, R.; Savin, R., et al. Abstract 550, Vol 102, No. 4, Pg 615. Soc. Inv. Derm. Baltimore 1994. "Efficacy of terbinafine 1 % cream in the treatment of moccassin-type tinea pedis: Results of placebocontrolled multicenter trials". Savin, R. C. et al., J Amer Acad Derm, Vol. 30. pp. 663 - 667, 1994. "Inocoterone and Acne -- The Effect of a Topical Antiandrogen: Results of a Multicenter Clinical Trial", Lookingbill, D. P. et al., Archives of Dermatology (1993) 128, No. 9, p. 1197 - 1200. Ronald C. Savin, M.D. 5 Last Updated 03/03/14 "Topical terbinafine and clotrimazole in interdigital tinea pedis: A multicenter comparison of cure and relapse rates with 1- and 4-week treatment regimens". Bergstresser, P.R.; Elewski, B.; Savin, R.C.; et al., J Amer Acad Derm, Vol. 28. pp. 648 - 651,1993. "Terbinafine in onychomycosis- a mini study." Savin, RC, Atton AV. Int Journal of Dermatology. 1993 Dec; 32 (12): 918-9 "Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and with Female Control Subjects". Cash, T.F.; Price, V.; and Savin, R.C. J Amer Acad Derm, Vol. 16. pp. 568 - 575, October 1993. "Minoxidil -- Update on Its Clinical Role", Savin, R.C. and Atton, A.V., Dermatoloqic Clinics, Volume 11, 55-64, January 1993. "A Method for Visually Describing and Quantitating Hair Loss in Male Pattern Baldness." Presentation Abstract # 317, 1992 Annual Meeting of the Society of Investigative Dermatology, Baltimore, 1992. "Efficacy of a One Week, Twice-Daily Regimen of Terbinafine 1% Cream in the Treatment of Interdigital Tinea Pedis", Savin RC et al. J Amer Acad Derm, Vol 26, pp. 956-960, June 1992. "The Effect of A Topical Antiandrogen Inocoterone Acetate (RU882) on Acne: Results Of A Multicenter Clinical Trial." Lookingbill, D.P., Savin, R.C., et al., Archives of Dermatology. 1992: Sept., 128(9): 1197-200. "A Double-Blind, Vehicle-Controlled Study of Clobetasol Propionate 0.05% (Temovate) Scalp Application in the Treatment of Moderate to Severe Scalp Psoriasis." Olsen, E.A.; Savin, R.C.; et al., J Amer Acad Derm 24, 443-447, 1991. "Topical Tretinoin For Treatment of Photodamaged Skin: A Multicentered Study", Weinstein, G.D., Nigra T.P., Pochi, P.E., Savin, R.C. et al., Archives of Dermatology, 127:659-665, 1991. "Oral Terbinafine Versus Griseofulvin In Thel - reatment of Moccasin-type Tinea Pedis." Savin, R.C., J Amer Acad Derm 23: 807-809, 1990. "Treatment of Chronic Moccasin-type Pedis with Terbinafine: A Double-Blind, Placebo-Controlled Trial." Savin, R.C.; Zias, N., J Amer Acad Derm 23: 804-807, 1990. "Treatment of Chronic Tinea Pedis (Athlete's Foot Type) With Topical Terbinafine." Savin, R.C., J Amer Acad Derm 23: 786-789, 1990. "Terbinafine (Lamisil) Versus Griseofulvin in Moccasin-Type Tinea Pedis." J Derm Treatment 1(suppl 43-46, 1990. 2.1: "Successful Treatment of Chronic Tinea Pedis (Moccasin-Type) With Terbinafine (Lamisil)." Savin, R.C., Clinical and Experimental Dermatology, 14:116-119, 1989. "Malignant Blue Nevus." Goldenhersh, M.; Savin, R .; Stenn, K., J Amer Acad Derm 19: 712-722, 1988. "Effectiveness of a New Orally Active Antifungal Drug, SF 86-327, In Treatment of Moccasin-Type Tinea Pedis." Savin, R.C., Abstracts of 17th World Congress of Dermatology, Part II, 130, Berlin, 1987. Ronald C. Savin. M.D. 6 Last Updated 03/03/14 "Use of Topical Minoxidil in the Treatment of Male Pattern Baldness." J Amer Acad Derm 16: 696-704, 1987. "Multicenter Double-Blind Clinical Trials of Ciclopirox Olamine Cream 1% in the Treatment of Tinea Corporis and Tinea Cruris." Bogaert, H.; et al., J Int Med Res 14:210-216, 1986. "Hair Transplants." Ambulatory Surgery and Office Procedures in Head and Neck Surgery. Lee KJ and Stewart C, eds. Grune & Stratton, Inc. 103-117, 1986. "A Comparison of Clobetasol Propionate 0.05% Ointment and an Optimized Betamethasone Dipropionate 0.05% Ointment in the Treatment of Psoriasis." Jacobsen, C.; Cornell, R.; Savin, R., Cutis 37:213-220, 1986. "Double-Blind Comparison of 2% Ketoconazole Cream and Placebo in the Treatment of Tinea Versicolor." Savin, R.C.; Horwitz, S.N., J Amer Acad Derm 15:500-503, 1986. "Treatment of Tinea Versicolor with a New Antifungal Agent, Ciclopirox Olamine Cream 1%." Cullen, S.I., et al., Clinical Therapeutics, Vol. 7, 1985. "Ketoconazole In Pityriasis Versicolor: Results of a Placebo-Controlled Trial." Or Therapy in Dermatomycoses, Symposium, Frankfurt, 97-100, Medicine Publishing Foundation, Oxford, 1985. "Comparative Study of Desoximetasone Ointment 0.25% Versus Fluocinonide Ointment 0.05% in Patients with Psoriasis." Savin, R.C.; Stoughton, R.B.; Vorhees, J.J.; Willis, I., Clinical Therapeutics 8:118-125, 1985. "Evaluation of Ciclopirox Olamine Cream For Treatment of Tinea Pedis: Multicenter, Double-Blind Comparative Studies." Clinical Therapeutics 7, No.4, 1985. "Systemic Ketoconazole in Tinea Versicolor: A Double-Blind Evaluation and One Year Follow-Up." J Amer Acad Derm 10:824-830, 1984. "Severely Dry Skin: Clinical Evaluation of a Highly Effective Therapeutic Lotion." Cutis 30:413-422, Sept 1982. "Skin Care: How to Avoid Fear of Frying." Tennis 17:76-77, May 1981. "The Failure To Preserve Direct Access to Dermatology in New Haven IPA." J Amer Acad Derm 3:319, 1980. "Photochemotherapy for Psoriasis -- PUVA Breaking Through 'The Heartbreak'. " Connecticut Medicine 42:698-703, 1978. "Are Hair Transplants Successful?" Cutis 22:121-123, 1978. "Potent Topical Steroids for Psoriasis: Comparison of Halcinonide and Betamethasone Dipropionate." Dermatology 1:34-38, 1978. "Desoximetasone - A New Topical Corticosteroid." Cutis 21:159-169, 1978. Ronald C. Savin, M.D. 7 Last Updated 03/03/14 "Comparative Topical Efficacy of Once Daily Diflorasone Diacetate and T.I.D. Betamethasone Valerate Ointment Applications." Cahn, M.M.; Hall, J.H.; Kirchenbaum, M.B.; Klein, L.; Leibsohn, E.; Peng, V.T.; Roth, H.L.; Savin, R.C.; Schlagel, C.A. Current Therapeutic Research 22:297-303, 1977. "Betamethasone Dipropionate in Psoriasis and Atopic Dermatitis." Connecticut Medicine 40, 1, 1976. "Halcinonide, A New Topical Anti-Inflammatory Steroid." The Journal of International Medical Research 4:34-36, 1976. "Keeping a Healthy Skin on Skis." The Physician and Sportsmedicine 3:48-52, 1975. "Dermatologic Evaluation for Military Service." Cutis 12:538-543, 1973. "Hair Transplants in Burn Scars and Other Alopecias." Connecticut Medicine 37:501-503, 1973. "Auricular Cancer." Arons, Marvin; Savin, Ronald. Amer J Surgery 122:770-776, 1971. "Hair Transplantation." Connecticut Medicine 33:47-51, 1969. "The Basal Cell Nevus Syndrome and Inflammatory Disease of the Bowel." Katz, Julian; Savin, Ronald; Spiro, Howard. Amer J Med 44:483-487, 1968. "Malignant Atrophic Papulosis (Part II): Histopathological Findings in Conjunctival and Eyelid Lesions." Fenton, Robert; Howard, Rufus; Savin, Ronald. Survey of Opth 1968. "Ichthyosis Hystrix and lchthyosis Vulgaris Studies in Keratolysis." Johnson, M.L.T.; Bloom, A.D.; and Savin, R.C., Abstracts, Sixth International Congress of the International Academy of Pathology, Kyoto, Japan, Oct. 1966, "Antibiotics and the Placebo Reaction in Acne." Savin, R.C.; Turner, M.C., J Amer Med Assoc 196;365-376, 1966. "Hyperglobulinemic Purpura Terminating in Xanthomas, Hyperlipemia and Myeloma." Arch Derm 92 : 679-686, 1965. Ronald C. Savin, M.D. 8 Last Updated 03/03/14