13th ICRS World Congress Preliminary Programme
Transcription
13th ICRS World Congress Preliminary Programme
1 2 0 16 Sorrento – Naples, Italy September 24 – 27, 2016 Preliminary Programme & Call for Abstracts 13th World Congress of the International Cartilage Repair Society & 5th ICCRA Congress on Foot & Ankle on Sept. 23 #ICRS16 www.cartilage.org Diamond Partner Diamond Partner Silver Sponsor Silver Sponsor Aesculap Biologics Facing a New Frontier in Cartilage Repair Biologic approaches to tissue repair and regeneration represent the future in healthcare worldwide. Aesculap Biologics is leading the way. Learn more at www.aesculapbiologics.com Aesculap Biologics, LLC | 866-229-3002 | www.aesculapusa.com Aesculap Biologics, LLC - a B. Braun company 3 Welcome by the President It’s a great honor to invite you to the 13th ICRS World congress in Sorrento – the world-famous beautiful city looking over the azure waters to the island of Ischia, Capri and the Bay of Naples. The ICRS is a unique forum to discuss multidisciplinary topics related to cartilage research and therapy including basic science, clinical investigation and industrial development. Our World Congress, held every 18 months, is especially important to accomplish our mission by providing a unique chance to meet our colleagues with the same interest and learn from the world’s top experts in this field. In addition, it may be a special experience to get acquaintance with new friends from all over the world and share productive and meaningful time over discussions on the common topics of interest. In addition, the combination of such academic activities with beautiful moments of cultural and social activities, this could be an unforgettable memory for each participant. The ICRS wants to provide such special opportunity to all of you. Our society is young and friendly and keen to welcome not only our members but also those who have rarely or never attended our congresses. Please come along and find out what we are all about. In recent years, we have taken special respect for integrating scientific and clinical aspects of each session so that we can all learn from each other. In this regard, our scientific committee lead by William Bugbee and Henning Madry has done a fantastic job in putting together the program, while the local organizing committee lead by Stefano Della Villa, Donato Rosa, Alberto Gobbi and Elizaveta Kon are working closely with Stephan Seiler at ICRS office to make sure the venue in beautiful Sorrento as well as the local culture and entertainment of Southern Italy are the best for you. Please mark your calendars for the 13th ICRS World Congress. Feel at home in our Society and join us at this great venue and enjoy a wonderful academic and cultural experience. I look forward to meeting you in Sorrento in September 2016. Norimasa Nakamura ICRS President 2015–2016 Welcome by the Local Committee We are so happy to welcome you to the magical atmosphere of Sorrento. We will only be a few miles from Naples’ International Airport and Capri, the island where Emperor Tiberius decided to transfer his palace to better guide the Roman Empire at the time of Jesus Christ’s life. Driving in Naples can be considered an extreme sport, in that here the laws of the road such as traffic signals appear to be optional, rules written as guidelines; but this is Naples and it should be embraced with the exuberance of a child let loose in a sweet shop. Nevertheless, do not panic, even if you feel you want to scream ‘brake, brake!’ because, although it may not seem like it, they do, incredible, really know what they are doing. Sorrento, what a sight! One of the most beautiful places on earth sitting above black volcanic cliffs, bordered by chalk mountains, the most visited place in Southern Italy, especially by the English which means that the language is spoken pretty good! We personally have a special relationship with the Sorrento peninsula, with one of us enjoying his honeymoon here and who cannot forget the natural beauty of the coast, the smell of the jasmine, the quality of the food, and the unique hospitality of the people. From this point of view, deciding to organise a scientific event in Sorrento is quite a risk. It is such a lovely place that despite an innovative scientific programme, the attendees could escape from the conference room to enjoy the beauty outside. As the Local Organising Committee, we will try to prevent, this by offering you the right combination of science, medicine and pleasure. If Tiberius was able, from this area, to run the Roman Empire for twenty years, we will try to do the same for the five days of Conference! It is just a matter of balance. During the day, we will find the right balance. Waking up early in the morning, we can enjoy an al fresco breakfast and a walk around the conference venue, taking in the spectacular view of the coastline. Then we move to the scientific venue, to enjoy the teaching of experts, the innovations in new technologies, the enthusiasm, and the energy of the young researchers during the free papers sessions. Different stimuli, from the richness of our scientific society, to a multidisciplinary group of people, sharing the same passion for cartilage tissue. Then coffee breaks and lunches will offer us the opportunity to enjoy again the hospitality of the Sorrento peninsula, where also a simple coffee tastes different. The afternoon and evening scientific sessions, and a visits to the technical exhibitions, will complete the professional part of the day. We cannot tell you anything about the dinners, because it will be a surprise. We can just anticipate that they will be joyful moments that take the best from our community: learning from each other, enjoying friendship, and trying to build together a healthier world thanks to our study, our experience and our passion. On behalf of the local organizing committee Stefano Della Villa, Congress Chair 2016 5 Welcome by the Scientific Programme Committee On behalf of the Scientific Programme Committee, we invite everyone to join us in Sorrento Italy on September 24–27 2016. The scientific program reflects the dynamic nature cartilage injury and repair, the growing importance of the ICRS as a preeminent organization and the tremendous efforts of its members in both basic scientific and clinical endeavors. The program builds on the overwhelming popularity and success of previous ICRS meetings and reflects our desire for scientists and clinicians to collaborate and share ideas. The program includes updates on current clinical strategies for repair of hyaline and meniscal cartilage, as well as emerging trends and controversies such as the use of stems cells, growth factors and gene therapy. Sessions on the osteochondral unit, synovial joint pathophysiology and osteoarthritis reflect the growing recognition of the role of subchondral bone behavior and the synovial joint as an organ. Cartilage repair in specific anatomic situations such as the patellofemoral joint, ankle, hip and upper extremity will be addressed. Practical “how to” sessions will cover fundamentals of basic research including study design and peer reviewed publication as well as advice on patient evaluation and surgical technique from leading experts. We will also feature the popular “mini battlefield” format where controversial questions will be passionately debated. We are confident this congress will allow everyone to enjoy a programme that truly reflects the “state of the art” in science and clinical practice cartilage repair. We look forward to seeing you in Sorrento, Italy. William Bugbee & Henning Madry Co-Chairs of the Scientific Programme Committee 2016 Advancing Science & Education In Cartilage Repair Worldwide! Organization Congress Chair – ICRS 2016 Della Villa Stefano, MD Isokinetic Medical Group 40132 Bologna, Italy Phone: +39 051 298 68 00 Email: [email protected] Members of the Local Organizing Committee Della Villa Stefano, Bologna, IT Gobbi Alberto, Milano, IT Kon Elizaveta, Bologna, IT Rosa Donato, Naples, IT Scientific Programme Committee Chairmen • Prof. MD William Bugbee Scripps Clinic Medical Group Department of Orthopaedics CA 92037 La Jolla, USA Phone: +1 858 554 79 93 [email protected] • Prof. MD Henning Madry Saarland University Experimentelle Orthopädie & Arthroseforschung 66421 Hamburg, Germany Phone: +49 684 116 24 500 [email protected] Members of the Scientific Programme Committee Adachi Nobuo, Hiroshima, JP Cole Brian, Chicago, USA Gomoll Andreas, Boston, USA Grande Daniel, Manhasset, USA Guilak Farshid, Durham, USA Hunziker Ernst, Bern, CH Martin Ivan, Basel, CH Spalding Tim, West Midlands, UK ICRS Executive Board President: Norimasa Nakamura, JP 1st Vice President: Ken Zaslav, USA 2nd Vice President:Alberto Gobbi, IT Secretary General: Elizaveta Kon, IT Treasurer: Tom Minas, USA Past President: Christoph Erggelet, CH Congress Organizing Office Cartilage Executive Office GmbH c/o Mr. Stephan Seiler Spitalstrasse 190 – House 3 CH-8623 Wetzikon ZH, Switzerland Phone: +41 44 503 73 70 Email: [email protected] Congress Venue Hilton Sorrento Convention Centre Via S. Antonio, 13 80067 Sorrento, Italy www.hiltonsorrentopalacehotel.com Hilton Convention Service Manager Angela di Benedetto Groups & Events Sales Executive [email protected] Official Hotel & Tour Booking Agency MP Congressi e Comunicazione c/o Ms. Bianca D’Angelo Via Posillipo 66/5, 80123Napoli, IT Phone1: +39 081 575 34 32 Phone2: +39 081 246 64 59 Mobile: +39 345 944 51 17 Web: www.mpcongress.it E-Mail: [email protected] E-Mail: [email protected] Please note: This is a preliminary programme. The information in this programme is subject to change without prior notice. For updated information, please visit frequently our website: www.cartilage.org 7 www.geistlich-surgery.com Autologous Matrix-Induced Chondrogenesis > A minimally invasive, effective one-step surgical technique for the treatment of chondral and osteochondral lesions larger than 1 cm2 > Based on microfracturing, the established first-line treatment > Natural protection of the super clot through the unique bilayer structure of Chondro-Gide® > Positive influence of Chondro-Gide® on chondrogenesis > Straightforward, cost-efficient surgical technique > Over 10 years of clinical experience Clinical results and scientific studies confirm the effectiveness of Chondro-Gide®, the leading collagen matrix in cartilage regeneration. Geistlich Pharma AG Bahnhofstrasse 40 CH–6110 Wolhusen [email protected] Chondro-Gide® is not available in all markets. Availability is subject to the regulatory or medical practices that govern individual markets. A clinically proven stem cell application for cartilage repair in talus, knee and hip Programme Overview Friday, September 23, 2016 Sunday, September 25, 2016 08.00 – 18.00 07.30 – 08.30 07.30 – 08.30 07.30 – 08.30 Plenary Session 5th ICCRA Congress on Foot & Ankle Technical Session Technical Session Technical Session Practical tips Evaluation for cartilage of Cartilage restoration Repair Decision Making – Cartilage Repair 08.30 – 09.30 Saturday, September 24, 2016 Plenary Session The Synovial Joint 10.00 – 18.00 09.45 – 10.45 09.45 – 10.45 09.45 – 10.45 Registration Special Session Special Session Special Session ICRS Meets Italy Allografts in Cartilage Repair Current Status of Non-Surgical Therapies 11.00 – 13.00 Sia & Sigascot Meets ICRS (Special session in Italian Language) 13.00 – 15.15 13.00 – 15.15 Opening Session Opening Session Cartilage Repair Update Meniscus Injury, Repair & Replacement 10.45 – 11.15 Coffee Break / Exhibition 11.15 – 12.45 Free Paper Sessions 13.00 – 14.00 Industry Satellite Symposia 15:15 – 16:00 14.15 – 15.45 Coffee Break / Exhibition Free Paper Sessions 16:00 – 17:00 16:00 – 17:00 16:00 – 17:00 16.00 – 17.00 16.00 – 17.00 16.00 – 17.00 Special Session Special Session Special Session Special Session Special Session Special Session Axial Alignment of the Knee Osteoarthritic Mistakes, Knee & Successes & Cartilage the Future Repair Rehabilitation Cartilage Battlefield: Mini Battles Cell-based therapies for Cartilage Repair 17.15 – 18.00 17.00 – 18.30 Opening Ceremony & Awards Scientific Poster Viewing Session 18:00 – 19.00 Honorary Lectures 19.00 – 20.30 19.30 – 23.00 Welcome Cocktail President’s Dinner (upon invitation only) 9 Monday, September 26, 2016 07.30 – 08.30 07.30 – 08.30 07.30 – 08.30 Technical Session Technical Session Technical Session Tuesday, September 27, 2016 Practical Tips for Practical Tips “The Frequent Cartilage Resto- for Improving Flyer” ration Procedures your Research 08.30 – 09.30 08.00 – 09.00 Plenary Session Stem Cells: Facts, Fiction – Today & Tomorrow Plenary Session The Osteochondral Unit 09.45 – 10.45 09.45 – 10.45 09.45 – 10.45 09.00 – 09.30 Special Session Special Session Special Session The ICRS Registry Cartilage Repair in the Hip Cartilage Repair in the Foot & Ankle Cartilage Repair in the Upper Extremity 09.30 – 11.00 Free Paper Sessions 10.45 – 11.15 11.00 – 11.30 Coffee Break / Exhibition Coffee Break / Intermission / Exhibition 11.15 – 12.45 11.30 – 12.30 11.30 – 12.30 11.30 – 12.30 Free Paper Sessions Special Session Special Session Special Session 13.00 – 14.00 Mini Battlefield – Part 2 The Moving from Patellofemoral Bench Joint to Bedside Industry Symposia 12.30 14.15 – 15.45 End of the Meeting Free Paper Sessions 15.45 – 16.45 15.45 – 16.45 15.45 – 16.45 Special Session Special Session Special Session ICRS meets ESSKA Novel Clinical Therapies YSOS forum 16.45 – 17.15 Coffee Break / Exhibition 17.15 – 18.30 ICRS General Assembly (For Members only) 19.30 – 23.00 ICRS Italian Night – Farewell Dinner Preliminary Scientific Programme Friday, September 23, 2016 International Pre-Congress Day on Cartilage Repair of the Ankle (ICCRA) The ICRS is proud to announce a collaboration with the International Society on Cartilage Repair of the Ankle to host a Pre-Congress directly preceding the 2016 ICRS World Congress in Sorrento. The course will be held on Friday, September 23rd at the Hilton Sorrento Palace, followed by a course dinner in the evening. The ICCRA Pre-Congress is co-chaired by John G. Kennedy of Hospital for Special Surgery in New York City, USA and Richard D. Ferkel of the Southern California Orthopaedic Institute in Los Angeles, USA. The local host is Francesca Vannini of the Rizzoli Orthopaedic Institute in Bologna, Italy. The Pre-Congress will feature a dynamic programme of international faculty discussing key issues in the field of ankle cartilage repair. An interactive programme will encourage participation of the delegates with case presentations, debates and technical tips. Participants are encouraged to book their accommodation at the official ICRS hotels as soon as possible and to continue the unique experience by participating in the World Congress occurring on September 24–27th. A distinct registration fee for the pre-congress is required as this is not included in the regular ICRS world congress registration fee. For further information, accommodations, programme and faculty, please visit our website www.cartilage.org Saturday, September 24, 2016 11.00 – 13.00 0.0 Sia & Sigascot Meets ICRS (Special session in Italian Language) 13.00 – 15.15 Opening Sessions – Where are we in 2016? 1.1 • • • • • • • • • Cartilage Repair Update Is the clinical algorithm for cartilage repair changing? Scientific update: the synovial joint milieu- implications for cartilage repair Scientific update on marrow stimulation Are adjunct procedures more essential than the repair? Scientific update on cell based repair strategies The osteochondral unit: normal and abnormalimplications for cartilage repair Scientific update on functional cartilage tissue engineering Overview of recent clinical studies in cartilage repair Open discussion 11 1.2 • • • • • • • • • Meniscus Injury, Repair & Replacement The science of meniscus pathology Lateral vs. medial meniscus: what is the difference? Meniscal repair: red, white and root Meniscectomy: how much is too much? The science of engineering meniscus structure and function Meniscal Replacement: Fact & Fiction Meniscus interventions: effect on mechanobiology Overview of recent clinical studies Open Discussion 15:15 – 16:00 Coffee Break / Exhibition 16:00 – 17:00Special Sessions 2.1 • • • • • Axial Alignment of the Knee – Importance in Cartilage Repair Natural history of the mal-aligned knee How I evaluate the mal-aligned knee? Biologic effects of realignment Alternatives to osteotomy Open Discussion 2.2 • • • • • The Osteoarthritic Knee & Cartilage Repair – Facts & Fiction When is a cartilage defect really osteoarthritis Arthroscopy and osteoarthritis: friends or enemies? How far can you go with cartilage repair? Outcome of cartilage repair in the arthritic knee Open Discussion 2.3 • • • • • Lessons learned from a Lifetime in Cartilage Repair: Mistakes, Successes & the Future Why we started the ICRS Lessons learned from 20 years of cartilage repair What is really important? Worst mistakes and best decisions Open Discussion 17:15 – 18.00 3.0 Opening Ceremony & Awards 18:00 – 19.00 4.0 • • Honorary Lectures Osteoarthritis is “Organ Failure”: what are the possibilities for changing natural History The Synovial Joint: Lesson learned in the development of Biologics & DMARDS for inflammatory disease 19.00 – 20.30Welcome Cocktail (Offered by the ICRS) Sunday, September 25, 2016 07:30 – 08:30 5.0 Technical Sessions 5.1 • • • • Practical tips for cartilage restoration procedures Osteotomies for varus malalignment Osteotomies for valgus malalignment Osteotomies for the patellofemoral joint Case discussions and Q & A Evaluation of Cartilage Repair in Animal Models What are your goals? Choosing the right animal model Comprehensive evaluation of osteochondral repair: what techniques do you need? Histologic analysis of cartilage repair tissue Other endpoints: from imaging to biomechanics 5.2 • • • • 5.3 Know before you go – Decision Making in Cartilage Repair • Patient evaluation • The new cartilage repair algorithm • Case discussions • Q & A 08:30 – 09:30 6.0 Plenary Session 6.1 • • • • • 09:45 – 10:45 The Synovial Joint: Homeostasis, Disease & Interventions The concept of joint homeostasis: scientific principles Inflammatory arthritis from RA to OA to PTOA Opportunities: is disease modification possible? How does joint inflammation affect cartilage repair? Open discussion 7.0 Special Sessions 7.1 • • • • • ICRS Meets Italy 20 years of experience in cartilage repair: The Italian Experience Biomaterials and tissue engineering Stem cells: past present and future Return to sport after cartilage surgery in high level athletes Open Discussion Allografts in Cartilage Repair Osteochondral Allografts: Indications & Outcomes New Strategies using Allogeneic Tissues & Cells Immunology of allografts Summary of the ICRS Allograft Meeting Brussels 2016 Open Discussion 7.2 • • • • • 13 7.3 • • • • Current Status of Non-Surgical Therapies Oral Medication: Algorithm Injectables: New hope or just hype Is there Hope for disease modifying drugs? Open Discussion 10:45 – 11:15 Coffee Break / Exhibition 11.15 – 12.45 8.0 Free Paper Sessions 13.00 – 14.00 9.0 Industry Satellite Symposia 14.15 – 15.45 10.0 Free Paper Sessions 16:00 – 17:00 11.0 Special Sessions 11.1 Rehabilitation • Current science on the effect of rehabilitation • Rehabilitation for ACI • New marrow stimulation techniques: New rehab protocols? • Quantitative measure of the effect of rehab • Open discussion 11.2 • • • • Cartilage Battlefield: Mini Battles Cells vs. No Cells We are paying too much? Chondral vs. Osteochondral Repair Is realignment really necessary? 11.3 • • • • • Cell-based therapies for Cartilage Repair What Cells make the best matrix? ACI now and the future Is there a role for allogeneic cells? MSCs: can they really make cartilage? Open Discussion 17:00 – 18:30 12.0 Scientific Poster Viewing Session 19:30 – 23:00 President’s Dinner (upon invitation only) Monday, September 26, 2016 07:30 – 08:3013.0Technical Sessions 13.1 Practical Tips for Cartilage Restoration Procedures • Microfracture • Cell therapies • Osteochondral procedures • Discussion and Q&A 13.2Practical Tips for Improving your Research – From Study Design to Statistics • How to write a successful research proposal • Getting your paper published in “Cartilage” • Analysis of a submitted manuscript: Pearl and pitfalls • Discussion and Q & A 13.3 “The Frequent Flyer” – Treating the Failed Cartilage Repair Patient • Identifying the reason for failure • Choosing the right technique: the revision algorithm • Case discussions, Q &A 08:30 – 09:30 14.0Plenary Session 14.1 Stem Cells: Facts, Fiction – Today & Tomorrow • MSCs: basic science • MSCs: clinical trials • Commercial and regulatory issues • Where will we be 5 years from now? 09:45 – 10:4515.0Special Sessions 15.1 Cartilage Repair in the Hip • Biologic Approaches for cartilage in the hip: Biomarkers, Stem Cells, PRP, HA • Arthroscopic approach for cartilage repair • Open surgical dislocation procedures and osteotomies • Imaging of the hip: Cartilage injury and structural dysplasias • Open Discussion 15.2 Cartilage Repair in the Foot & Ankle • Unique features of the ankle: Implications for cartilage repair • Surgical approaches • Cartilage repair algorithm in the foot and ankle • Treatment of isolated and complex lesions • Open Discussion 15 15.3 Cartilage Repair in the Upper Extremity • Unique features of the shoulder: implications for cartilage repair • Cartilage repair algorithm in the shoulder • Is Bipolar resurfacing possible? • Cartilage repair in the elbow • Open Discussion 10:45 – 11:15Coffee Break / Exhibition 11.15 – 12.45 16.0 Free Paper Sessions 13.00 – 14.00 17.0 Industry Symposia 14.15 – 15.45 18.0 Free Paper Sessions 15:45 – 16:45 19.0 Special Sessions 19.1 ICRS meets ESSKA: Meniscal Repair & Replacement • Cartilage and meniscal interaction: scientific principles • Update on meniscal repair and replacement • The lateral meniscus • Innovative techniques for meniscal repair and replacement • Open Discussion 19.2 Novel Clinical Therapies • Augmented microfracture: are we paying for better? • PRP and cartilage repair • Bone marrow aspirates • Synthetic osteochondral replacement • Open Discussion 19.3YSOS forum: the future leaders in cartilage repair • Developing a cartilage repair practice • Clinical research programs • Clinician and scientist collaboration • Past present and future of YSOS • Open Discussion 16:45 – 17:15 Coffee Break / Exhibition 17:15 – 18:30 20.0 ICRS General Assembly (for members only) 19:30 – 23:00 ICRS Italian Night – Farewell Dinner (Price € 80.00 per Person) Tuesday, September 27, 2016 08:00 – 09:00 21.0 Plenary Session 21.1 The Osteochondral Unit • Basic science of the osteochondral unit • Data from translational models • Clinical patterns of osteochondral injury and disease • Treatment of subchondral bone in cartilage repair • Open Discussion 09:00 – 09:30 21.2 The ICRS Registry 09:30 – 11:00 22.0 Free Paper Sessions 11:00 – 11:30 Coffee Break / Exhibition 11:30 – 12:30 23.0 Special Sessions 23.1Cartilage Repair Mini Battlefield – Part 2 • Meniscus allografts: good or bad? • Stem Cells vs. Chondrocytes • Marrow stimulation: is augmented better? • Osteotomy versus arthroplasty 23.2 The Patellofemoral Joint: The Biggest Challenge in Cartilage Repair • Understanding patellofemoral dysplasias and malalignment • Making sense of realignment procedures • Controversies in cartilage repair: what techniques to use in the PF joint • Update on clinical outcome studies • Open Discussion 23.3Moving from Bench to Bedside – Translational Cartilage Repair • Gene therapy: basic science • Gene therapy: clinical data • FGF-18 clinical update • Outlook: what is coming next? • Open Discussion 12.30End of Meeting 17 ICRS Technical Sessions These early morning sessions will be chaired by world-renowned leaders and provide a unique possibility to obtain a compact knowledge about a specific topic in a small group. These sessions are geared towards young scientist / clinicians and seasoned specialists. In addition, this time allows delegates to bring their problem and complex cases for discussion with the opinion leaders in cartilage repair. Preregistration is required to sign-up for these sessions during the online congress registration process. These courses are not included in the congress registration fee and the number of participants is limited to 40 participants for each session. Registration Fees Residents, Students, Junior-Members ICRS-Members Non-Members Company Representatives Euros 15.00 Euros 25.00 Euros 40.00 Euros 50.00 YSOS Star – Free Paper Sessions This new session will present the best papers submitted by the YSOS-Young Scientists & Orthopaedic Surgeons. Entry is only for authors under 40 years of age: for surgeons within their first 5 years of practice and for Scientists in their first 2 years following PhD qualification. Please indicate on the abstract submission form whether your submission should be considered for the YSOS-Young Investigator Award in addition to the normal abstract submission process. 5th ICCRA Congress Registration Fees Sept 23, 2016 from 08.00–18.00 ICCRA Ankle Course Early Late On-Site Registration Fees Prior to May 30 Until August 20 as from August 21 Resident/Students* € 150.00* € 200.00* € 250.00* ICRS-Members € 200.00 € 250.00 € 300.00 Non-Members € 250.00 € 300.00 € 350.00 Industry Representatives € 300.00 € 350.00 € 400.00 The ICCRA Congress on Sept 23 is preceding the ICRS World Congress. It is organized independently by ICCRA and co-chaired by John G. Kennedy of Hospital for Special Surgery in New York City, USA and Richard D. Ferkel of the Southern California Orthopaedic Institute in Los Angeles, USA. The local host is Francesca Vannini of the Rizzoli Orthopaedic Institute in Bologna, Italy. This full day ICCRA PreCongress will feature a dynamic programme of international faculty discussing key issues in the field of ankle cartilage repair. An interactive programme will encourage participation of the delegates with case presentations, debates and technical tips. Pre-registration is required to sign-up for the ICCRA Sessions. The ICCRA congress is not included in the ICRS congress registration fees. For further information, accommodation, programme and faculty, please visit our website www.cartilage.org Call for Abstracts – Authors’ Information Call for Abstracts The scientific programme committee is pleased to invite all authors wishing to present a paper or a poster at the ICRS 2016 to submit their abstracts latest until April 10, 2016. No extension of this deadline will be possible. The overall best rated Abstract and Posters will be awarded by the Society. • Podium Presentations Free papers related to all topics in cartilage repair will be presented during 16 free paper sessions. Speaking time is 7 minutes plus 3 minutes for discussion. The speaking time must strictly be observed by the presenters. If an abstract is accepted as an oral presentation, presenters must speak in fluent English and be prepared to answer questions from the audience and moderators. All session rooms are equipped with networked computer projection. Presen ters are requested to bring their Power Point presentation (Windows 10, XP or Windows 7) on a CD-ROM or USB stick and to check-in at the Preview Center 3 hours prior to their presentation. Detailed information will be sent to the presenters on time. • Electronic Posters One of the main benefits of an electronic poster exhibit is the post-congress availability of the posters for many years in the ICRS member’s area. Our scientific cartilage knowledge database is fully searchable by title, poster ID, authors, full text and image annotation. Information on how to use the electronic poster submission system will be sent to the authors of the accepted posters. An independent jury will judge the electronic posters by online blind grading with regard to scientific content, educational value and visual impression. Awards for the 6 best electronic posters and best abstracts will be given during the ICRS Opening & Awards Ceremony on Sunday, September 24, 2016 at 17.00 hs. • Traditional Wall Posters In addition to the electronic posters, which must be submitted on a manda tory basis, the authors are invited to produce a traditional poster for the poster walls as well. If your abstract is accepted as a poster, you will be requested to submit your electronic files to the ICRS online poster submission system and you should bring with you a traditional poster for the poster exhibit by reserving your poster wall in advance through our Office. Submission of Abstracts – Guidelines Scientific abstracts must be submitted in impeccable English within the following structure: Purpose – Materials & Me thods – Results – Conclusion and must be written according to the few abstract submission instructions to be found in the ICRS abstract online submission system. Abstract length is limited to a maximum of 300 words and may contain up to 2 graphs, pictures or tabs. For experimental clinical studies and animal studies, a copy of the approval received by the local ethical committee must be sent to our Executive Office after successful submission of your abstract. Abstract submission Deadline Abstracts may be submitted online through April 10, 2016 at noon CET (Central European Time) by accessing our 19 Call for Abstracts – Authors’ Information online submission system on the ICRS website. No abstract submissions by letter, fax or E-Mail will be accepted and no extension of the submission deadline will be granted. ICRS will NOT edit abstracts for language issues, typing, spelling, or grammatical mistakes. There is no fee charged to submit an abstract for ICRS 2016 and you may submit as many abstracts as you wish. However, it is highly recommended to not leave your submissions until the very last day. Presentation Preference Submitted abstracts will be peer-reviewed and may be accepted for either an oral- or a poster presentation. Submitters may indicate their presentation preference during the submission process but the Scientific Programme Committee reserves the right to define the final presentation type. No podium presentations can be guaranteed to any author. Confirmation of Abstracts Scientific contributions will be confirmed by end of April 2016 by E-Mail to the presenting author. The presenting author must inform all co-authors of the notification result. Presenting authors of accepted abstracts will be requested to reconfirm their presentations and they are expected to register normally to the congress. They must cover their own travel, lodging and registration fees. Supplement Journal “Cartilage” Congress abstracts are citable and will be published electronically in the congress supplement of our official Journal “Cartilage”, published by Sage ISSN 1947-6043 and in the printed congress abstract book. We furthermore encou rage all authors to additionally submit their full manuscripts to our peer reviewed journal “Cartilage” which publishes full-length original manuscripts on all types of cartilage including articular, nasal, auricular, tracheal/bronchial, and intervertebral disc fibrocartilage. Manuscripts on clinical and laboratory research are welcome. Instructions to authors for submissions are available at http://cart.sagepub.com Financial Disclosure Statement Submitting authors must complete a Financial Disclosure Statement on behalf of all authors. Disclosures will not be seen or taken into consideration for the abstract grading process nor for the decision of acceptance of an abstract. Awards & Honours ICRS 2016 • 1 x Overall Best Rated Abstract We request all submitters to cooperate • 6 x Best E- Posters in this by: 2 x Magna Cum Laude 1. Declaring any potential conflict of 2 x Cum Laude interest by any of the authors when 2 x Certificate of Merit submitting an abstract. • 1 x ICRS Lifetime Award 2. Declaring any commercial role in the • 1 x Young Investigator’s Award related research of any Co-author on (US$ 1000.00) the first slides for podium presentations or on the posters for poster presentations. Abstracts – Authors’ Information CME Credits The ICRS 2016 Congress intends to be accredited by the European Accreditation Council for Continuing Medical Educations – EACCME, an institution of the European Union of Medical Specialists – UEMS, recognized by AMA. Computers are available in each session room for accessing the speakers’ pre sentations. The network of our computers in the session rooms and the AV Center are equipped and run with Microsoft Windows 7. Macintosh formats are not Information on accreditation and the recommended. If you prefer to use number of CME credits will be available Macintosh formats, please contact the soon at www.cartilage.org AV Centre well in advance before your presentation. Our technicians will have Speaker Service / AV Centre enough time to verify and adapt your Please note that only digital material will presentation, if needed. be allowed for oral presentations. The material must be in English and must Speaker’s presentations should be debe provided on CD-ROM or USB memory livered as a standard in Microsoft Office stick in (Windows 10, 7 or XP format) to format to avoid any technical problems be placed on the central server on-site. with the presentation system. If you Presentations cannot include any pro- have videos included in your PP pre motional commercial messages. It will sentation, make sure that they run in not be possible to use your own laptop the most commonly used video formats. or notebook for your presentation in the If you have any doubt, please contact session rooms. the ICRS Office at least 15 days before the congress. It is your responsibility to It is mandatory that the data carriers are make sure that your video runs on our delivered to the Speaker Ready Room standardized congress IT / AV system. at least 3 hours prior to your session. Important Dates & Deadlines Abstract Submission Deadline Abstract Notification Letters Cancellation of Registration (Refund 80%) Early Bird Registration Fee Confirmation of Registration Latest Hotel Reservation Deadline Hotel Cancellation Deadline Cancellation of Registration (Refund 50%) Late Registration Fee applies Cancellation of Registration (no refund) April 10, 2016 End of April 2016 May 30, 2016 May 30, 2016 immediate online June 15, 2016 June 15, 2016 before August 20, 2016 as from August 21, 2016 after August 21, 2016 21 General Information Congress Organizer Cartilage Executive Office (CEO) GmbH Spitalstrasse 190 – House 3 8623 Wetzikon ZH, Switzerland Phone: +41 44 503 73 70 Fax: +41 44 503 73 72 [email protected] Congress Venue Hilton Sorrento Palace Via S. Antonio, 13, 80067 Sorrento, Italy Phone: +39 081 878 1394 Fax: +39 081 878 1397 www.Hilton.com/Sorrento Welcome to Sorrento The historical town of Sorrento at the famous Amalfi Coast is nestled between picturesque cliffs and looks across toward the stunning Bay of Naples and Mount Vesuvio. Visit the nearby scenic cities of Positano and Naples. Outside of Sorrento, there are many places of interest. Tour the beautiful island of Capri, the small town of Amalfi and the famous ancient city of Pompeii, as well as the Isle of Ischia, Ravello and Hercolaneum. The local tourist focal point is Piazza Tasso, where tables and chairs crowd the central square, built over a gorge. Not to be missed in Sorrento: Basilica of Saint Antonino, The Cathedral of Sorrento, Marina Grande, Correale Museum and more. The tourist information office is located just off Piazza San Antonino, in the old town. You can pick up free town maps, leaflets and timetables for local transport. Hilton Convention Service Manager Angela di Benedetto Groups & Events Sales Executive [email protected] Accommodation / Housing Service MP Congressi e Comunicazione c/o Ms. Bianca D’Angelo Via Posillipo 66/5, 80123Napoli, IT Phone1: +39 081 575 3432 Phone2: + 39 081 2466459 Mobile: +39 3459445117 Web: www.mpcongress.it E-Mail: [email protected] E-Mail: [email protected] General Information Venue Location: Surrounded by a huge citrus garden, the Hilton Sorrento Palace is only a 15 minutes-walk from the historical center of Sorrento, which is an ideal spot for shopping or enjoying the bustling nightlife. Hilton Sorrento Palace offers breath-taking sea views. In front is the enchanting Bay of Naples dominated by Mount Vesuvius, and from behind Punta Campanella. The Hotel offers 37,000 sq. ft. of meeting space, inclu ding an auditorium to accommodate up to 1,500. With 24 meeting rooms it is one of the largest convention hotels in Italy. •By Bus: From the airport arrival terminal you can get busses and mini vans directly to the Sorrento or to the Naples train station. •By Boat: Sorrento is linked to Naples’ Harbour “Molo Beverello” by ferries, fast ferries, and hydrofoils. The hydrofoils and the fast ferries take approx. 30 mins. • By Taxi: The cost of taxi is of around Euros 130 from the airport to Sorrento. Time Zone Standard time zone daylight saving: UTC/GMT +2 hours. Time zone abbreviation: CEST – CenTravel and Transportation Napoli Capodichino Airport (NAP) is tral European Summer Time around 55 km or a 60-minute drive away from the the Hilton Sorrento. For Language The official congress language is Engmore information please visit: lish. No simultaneous translation will http://www.aeroportodinapoli.it/ be provided. Italian is the language •By Car: Once in Naples take the A3 spoken in Italy. English is widely spomotorway, exit to Castellamare and ken and understood throughout the follow signs to Penisola Sorrentina. country. Distance between Napoli-Sorrento: 60 Km. For those who would like to dis- Climate cover the Amalfi Coast a car rental is The Mediterranean climate of Sorrento can be easily characterised by recommendable. its lengthy, sunny summer months •By Train: If you arrive with Trainitalia and mild winter weather. Many touryou need to get off in Napoli Centrale ists favour visiting Sorrento during the or Napoli Piazza Garibaldi. In both sta- spring or fall seasons, when the clitions you will find Circumvesuviana mate is pleasantly warm and dry. End trains. Take a train to Sorrento which of September temperatures in Sorrenis where the train terminates. The jour- to vary between 15–25°C (60–80°F). ney is approx. 75 minutes. 23 General Information Credit Cards / Cash Machines All major credit cards are widely accepted. Bank cash machines (ATM) can be found easily and debit cards are also widely used. If you are using a foreign card at a bank machine, your money will be disbursed in Euros. Currency The currency in Italy is the Euro. 1 € Euro ≈ 1.00 US$ (Date of printing, January 2016) Sweden. Visitors from the Schengen Area can hold a valid ID card to travel within this area. Visitors from outside the Schengen Area must hold a valid passport. The following countries do not need a VISA to enter Italy as a tourist: Andorra, Anguilla, Argentina, Australia, Bermuda, Bolivia, Brazil, Brunei, Bulgaria, Canada, Cayman Islands, Chile, El Salvador, Falkland Islands, Guatemala, Honduras, Israel, Japan, Liechtenstein, Malaysia, Mexico, Monaco, Montserrat, New Zealand, Nicaragua, North Korea, Panama, Paraguay, Romania, Saint Helena, San Marino, Singapore, Turks and Caicos Islands, Uni ted States Uruguay, US Virgin Islands, Vatican City, Venezuela. Tipping Service charges are typically included in the bills in Italy. However, a small tip of 1–5 Euros for a friendly service is generally expected. This applies to waiters, bellmen, barbers and hairdressers, taxi drivers, etc. Tips should rather be given in cash and not be ad ded to the credit card charge on the This information may change without bills. further notice. If you have any doubts about your current VISA need to enter Health Care Italy, we highly recommend checking Special Vaccinations are not required with the Italian Embassy or Consulate for entry into Italy but an individual in your respective country. travel & health insurance is highly re commended because health insurance Disclaimer plans often do not extend full coverage The ICRS and the congress organfor medical services received outside izer cannot accept any liability for the the country of residence. acts of any suppliers to this meeting nor of the safety of any attendee Entry Formality / Visa while in transit to or from this event. The European borderless region known Participants are requested to carry as the “Schengen Area” includes the proper travel and health insurance as following countries: Austria, Belgium, the ICRS cannot accept liability for any Czech Republic, Denmark, Estonia, accidents or injuries that may occur. Finland, France, Germany, Greece, Hungary, Iceland, Italy, Latvia, Lithu- Information in this programme is subania, Luxembourg, Malta, The Nether- ject to change without prior notice. lands, Norway, Poland, Portugal, Slo- For updated information please visit vakia, Slovenia, Spain Switzerland and frequently our congress website at www.cartilage.org General Information Cancellation of the Congress by the Organizer Congress fees will be reimbursed if the congress is cancelled for other reasons than war, warlike events, and acts of terrorism or sickness epidemics. In the latter circumstances only a proportion of the congress fee would be refundable. Technical Industry Exhibition A technical industry exhibition with will take place at the Hilton Sorrento Convention Centre. It will be open every day throughout the meeting and exhibitors from around the world will present a wide range of orthopaedicand cartilage repair related products. Participants are encouraged to take advantage of this unique opportunity to be updated with the most recent advances and latest news from our industry partners. Interested companies may contact the ICRS Executive Office for further exhibit & sponsoring information. security precautions to ensure the maximum possible safety for all participants. Identity check controls may occur at any time by the security staff. Congress badges are personalized, not transferable and guarantee individual access to different section of the event. For organizational and security reasons, badges have to be worn all the time at the congress v enue. Electricity, Weights and Measures • Electricity: 220 volts 60 hz • Weights: Kilo/Gramm system • Measures: Metric system Complimentary Internet/WLAN As a special courtesy, ICRS will provide free WLAN Hot Spots and a public Internet Corner to all attendees and exhibitors in the convention area. Smoking The ICRS World Congress is a nonsmoking congress. Smoking is not Intermissions permitted at the Hilton Sorrento and During intermissions, coffee, tea and its Conference Centre except in desigrefreshments will be served in the exhi- nated smoking areas. bition area as a courtesy from the ICRS. Mobile Phones Services for Persons with Disabilities All attendees will be requested to Please inform the ICRS office or indi- turn off their mobile phones during all cate on the accommodation online scientific sessions. booking form any special requirements you may have to allow us to Recording/Pictures best serve you. The Hilton Sorrento Taking photos or video/ audio recording has international-standard facilities during the scientific presentations or for the physically challenged, inclu from the poster area is strictly prohibited. ding access ramps, elevators and toi- Note that the majority of the Presentalets for people with special needs. tions, posters and many officially recorded sessions will become available online Security / Badges after the congress at the ICRS website in The safety of all congress attendees is the members’ area, therefore there is no of utmost importance to our society. The need to take pictures during the sessions ICRS and the Hilton Sorrento have taken or from the poster exhibits. 25 Congress Registration All attendees must register online for the congress at www.cartilage.org Students, Residents, Physiotherapists and Nurses must provide a proof of their training /residency or professional status to receive our highly reduced registration rates. This document must be sent to [email protected] immediately after registration to confirm the specially reduced fee. Register until June 15, 2016 in order to receive a highly reduced registration fee! Cancellation of Congress Registrations – Name Changes Written notification is required for all congress cancellations and name changes. Notifications should be sent to the Cartilage Executive Office [email protected] Refunds for congress cancellations are as follows: • 80 % until May 30, 2016 • 50 % until August 20, 2016 • No refund thereafter Congress Registration Fees Early – Prior to May 30, 2016 Resident/Students* € 290.00* Physiotherapists/Nurses* € 290.00* ICRS-Members € 390.00 Non-Members € 550.00 Industry Representatives € 650.00 Accompanying Person € 90.00 Late – May 31 – August 20, 2016 Resident/Students* € 390.00* Physiotherapists/Nurses* € 390.00* ICRS-Members € 490.00 Non-Members € 650.00 Industry Representatives € 750.00 Accompanying Person € 100.00 In case of a congress cancellation due to rejection of an abstract, the full amount of the paid registration fee will be refunded. Name changes will be charged with a fee of € 100.00. Join ICRS Now! Non-member attendees who apply for ICRS membership 2016 right before their congress registration will immediately profit from our highly reduced members’ fee. ICRS Members who are not in good-standing with their membership dues 2015 / 2016 will automatically be charged with the non-member fee. Included in your registration fee: Access to all scientific sessions (except early morning workshops) Access to the technical industry exhibition Access to the scientific poster exhibition Welcome Reception, Poster Cocktail & Coffee Breaks Free Internet Access (Internet Corner & WLAN available) *Registrations to be accompanied Congress Bag with Main by a certificate signed by the head of Programme & Abstract Book department or valid student or profes- Badge and Certificate of Attendance CME Credits (to be confirmed) sional ID Badge & Certificate of Attendance On-Site – as from August 21, 2016 Resident/Students* € 450.00* Physiotherapists/Nurses* € 450.00* ICRS-Members € 550.00 Non-Members € 690.00 Industry Representatives € 850.00 Accompanying Person € 110.00 Official Housing & Tour Booking Agency MP Congressi e Comunicazione c/o Ms. Bianca D’Angelo Via Posillipo 66/5, 80123Napoli, IT Phone1: +39 081 575 3432 Phone2: + 39 081 2466459 Mobile: +39 3459445117 Web: www.mpcongress.it E-Mail: [email protected] E-Mail: [email protected] Hotel, Tour & Transfer Booking Group Reservations – Industry MP Congressi is pleased to receive group reservations requests for accommodations in Sorrento (10 + more rooms). Please kindly contact MP Congressi for any assistance and special arrangements. Payment A credit card is necessary to make your hotel reservation and full payment of the reserved Hotel Rooms plus a handling fee of Euro 18.00 is required to guarantee and secure your hotel reservation. Hotel, tours & transfers will be charged by MP Congressi to your credit card upon booking. All the hotels in Sorrento charge a separate city tax of 2,00 to € 4.00 per person to be paid directly by the guests in the hotel upon check-out. MP Congressi has been designated as the official Congress Travel Agency for the ICRS 2016. MP Congressi will take care of your local accommodation needs, transfers & tours in Sorrento. An adequate number of rooms have been reserved and special room rates have been obtained to your advantage. An overall reservation handling fee of Euro 18.00 will be additionally charged Cancellation Charges & Changes for each individual accommodation Cancellations are to be addressed to MP Congressi directly in writing. The reservation. following cancellation fees will apply: Very Important: End of September is still high season in Sorrento and find- For Hotel reservations: ing suitable accommodation in Sorren- • Until June 15, 2016: Charge of 1 night to might be difficult. The ICRS has plus handling fee of € 18,00. made a major commitment to Sorrento • From June 16, 2016: Charge of 2 Hotels in order to secure a reasonable nights plus handling fee of € 18,00. block of quality hotel rooms at compet- • After July 15, 2016 and No-Shows: itive rates. We kindly ask participants Charge of the entire reservation and industry partners to book their ho- period plus handling fee. tel rooms as early as possible but not later than June 15, 2016 through our of- For Tours & Transports: ficial housing partner MP Congressi. • Until July 15, 2016: Cancellation free Hotel Rooms will be allocated on a of charge first-time first-serve basis in each cat- • After July 15, 2016: No refund egory and hotel. For individuals, only online registration is accepted through Request for Changes our website www.cartilage.org. Reser- Requests for changes must be directed vations can only be confirmed upon to MP Congressi in written. Room night reductions of existing reservations are availability by MP Congressi. subject to the cancellation conditions indicated above. 27 Tours & Social Event Information Important: The ICRS supports compliance with international ethical standards and therefore emphasizes that participants and accompanying persons who would like to attend tours or social events shall bear all related costs themselves. Welcome Reception Italian Night – Farewell Dinner Saturday, September 24, 2016 19.00 – 20.30 Monday, September 26, 2016 19.30 – 23.00 Participants, industry representatives and accompanying persons are invited to join the opening ceremony and welcome cocktail at the Hilton Hotel. This reception is offered to you on a complimentary basis by the ICRS. After the cocktail, participants have free time for their own leisure to discover Sorrento and enjoy one of the many nice restaurants / bars at the historical centre of Sorrento. President’s Dinner (upon invitation only) Sunday, September 25, 2016 19.30 – 23.00 Free evening for participants’ individual programmes and for industry related events. The Hotel Concierge and/or our official agent MP Congressi will be pleased to recommend and book at table for you at one of your favourite restaurants in town. Italian style entertainment for everyone! Join us for a magic evening with mouthwatering Italian cuisine, drinks and assist amazing folkloric presentations. Let you be immersed in a magical atmosphere together with your colleagues from all around the world. Here, you can look forward to delicious specialties, regional beverages and enjoy typical music and cultural show acts. Price per person: € 80.00 (incl. dinner, drinks & entertainment) Accompanying Persons’ Programme All tours require a minimum participation of at least 15 participants. If a minimum participation is not reached 3 weeks prior to the excursion date, a tour may be cancelled and all booked participants will be reimbursed in full. Start and ending point of all tours is the Hilton Sorrento. Panoramic Tour – Sorrento Friday, Sept 23, 2016 14.00 – 17.00 Saturday, Sept 24, 2016 08.30 – 11.30 Meet your Guide at the Hilton Sorrento Palace Hotel and start the visit of Sorrento on foot. From Piazza Antiche Mura, walk to the old city centre: Via S. Cesareo, the heart of the town, and visit of the beautiful Cloister and Church of S. Francesco. Visit the Cathedral, built in the 15th century in Romanesque style. After the walking tour transfer to the surrounding hills of Sorrento for a panoramic tour of the beautiful countryside going through the small towns of Massa Lubrense, Marciano, Termini, Monticchio and Sant’Agata. Throughout the tour you will see views of the Isle of Capri and Ischia. The Mount San Costanzo and the Mount Vesuvius and the two bays of Salerno and Naples. Price per person € 40.– (incl. English speaking guide, bus transport) Lemon Tour – Costiera Amalfitana Saturday, Sept 24, 2016 08.30 – 17.00 Pick-up at Hilton Sorrento Palace Hotel in Sorrento by deluxe/air-conditioned coach. An English speaking guide will accompany the group for a beautiful drive along the Amalfi coast to Positano, Amalfi and to Ravello. The Amalfi Coast is the stretch of coast bell, located south of the Sorrento Peninsula, overlooking the Gulf of Salerno. It takes its name from the town of Amalfi, the central nucleus of the Coast not only geographically but also historically. The Amalfi Coast is known for its diversity: each of the coast counties has its own character and its own traditions. During the first part of the day we cross the romantic Positano. The first stop is Amalfi, ancient Maritime Republic, which main square is dedicated to Flavio Gioia, the symbolic figure of the invention of the 29 Accompanying Persons’ Programme compass sea coast. The centre is dominated by the imposing staircase and the facade of the cathedral, dedicated to St. Andrew, famous for its cloister and museum complex. There will be the opportunity to have free time for shopping or to visit the medieval Cathedral of St. Andrew, known for its beautiful facade in Amalfi style. Continue by bus to Ravello (300 meters on the sea),to the discovery of the ancient medieval village. In this delightful little town, you can visit the medieval Villa Rufolo with breath-taking views and a source of inspiration for many artists, including Richard Wagner, who he found the atmosphere to imagine the garden of Klingsor of his Parsifal, in fact to commemorate the German composer’s presence in the villa is organized every year the music festival in his honour. Return to Sorrento. excavated and made accessible to the public since the mid-18th century. You will get a vivid impression of the opulent lifestyle enjoyed by the wealthier citizens of the Early Roman Empire. Pompeii is one of the most meaningful testimonies of the Roman civilization. The city resurfaces from the dark of the centuries as it was to the moment in which it came covered by one layer of escaped ashes, with the devastating eruption of the Vesuvius. Today, this UNESCO World Heritage Site is one of the most popular tourist attractions of Italy, with approximately 2,500,000 visitors every year. Since certain areas might be closed for renovation, the exact itinerary will be communicated by the guide during the tour. Price per person € 55,00. (includes English speaking guide, bus and parking, entrance fee to the archaeological Price per person € 80,00. (incl. English site.) speaking guide, bus transport, parking in Amalfi and Ravello, entrance fees to the cloister Chiostro del Paradiso” and Villa Rufolo in Ravello) Archaeological Tour – Pompeii Friday, Sept. 23, 2016 08.20 – 13.00 Sunday, Sept. 25, 2016 08.30 – 13.00 Pick-up at Hilton Sorrento Palace Hotel. Pompeii is one of Italy’s most precious archaeological sites. It is incredibly well preserved. When Vesuvius erupted on 24 August AD 79, it engulfed the two flourishing Roman towns of Pompeii and Herculaneum, as well as the many wealthy villas in the area. These have been progressively Accompanying Persons’ Programme Luxury Tour – Capri Monday, Sept 26, 2016 08.30 – 17.00 Pick up at Hilton Sorrento Palace Hotel and transfer to the port of Sorrento. Board on a hydrofoil to cross over to Capri, a journey of about 30 minutes. Capri, is a small island with rich natural beauty. At the port of Sorrento, we take a fast hydrofoil with all the comforts to make pleasant the fascinating journey from where you can admire the Sorrento Peninsula since. After about 20 minutes by boat you arrive at the Marina Grande in Capri, the small port of the island. Transfer from Marina Grande to Anacapri by local minibus. This beautiful village, today is a town in itself, is an integral part of the island. Inhabited since Roman times, as witnessed by numerous remains, Anacapri had its heyday between the nineteenth and twentieth centuries, when it became a retreat for artists from all over Europe, who came here to spend their holidays and find inspiration. In Anacapri you can visit the famous Villa San Michele, which was bought and restored in 1895 by the Swedish Doctor Axel Munthe who fell in love with the ruins of a chapel, consisting of once smashed and some crumbling walls. Transfer to Capri Town by bus, with its Piazzetta and streets lined with designer shops, meeting place of VIPs and scenic spot of great beauty. Then you will have free time for shopping or go down a short walk to the Gardens of Augustus. Return by bus to the port of Marina Grande and by hydrofoil from Capri to Sorrento. With the assistance of the tour guide, time and weather permitting, you can book a boat tour of the coast or visit the Blue Grotto, which is known around the world for its beauty. Entrance fee to the Blue Grotto or boat tour of the island are not included. Price per person € 110,00. (incl. 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