ChromaDex Tea Services

www.chromadex.com
ChromaDex Tea Services
setting THE standard
2
ChromaDex Tea
Introduction
ChromaDex has established a Tea
Services Division to meet the complex
needs of a rapidly changing global tea
industry.
In the USA alone, sales of tea beverages have
skyrocketed from sales of less than $1 billion
dollars annually in 1990 to an estimated $6.8
billion in 2008. Forecasts point towards sales
topping $10 billion in the next two years (USA).
Sales of consumer products containing tea as an
ingredient now outnumber beverage teas sold
worldwide. Yet, in spite of the desirable increase
in demand for tea products, especially specialty
tea oriented, a number of factors are adding
extra pressure to the otherwise stellar industry
growth patterns; intense competitor, regulatory
and producing origin actions are shaking up
the tea business landscape. ChromaDex Tea
Services are modeled after our successful
natural products industry divisions which have
productively served companies within the dietary
supplement (nutraceutical), food and beverage,
cosmetic, and pharmaceutical sectors for many
years. Whether your tea company, product or
technology needs basic analytical services or
comprehensive research and development
support, ChromaDex Tea Services can assist
your team as required.
Introduction
3
Tea Average Data
5
Understanding ORAC & Folin C
7
Reference Standards and Materials (CRM and BRMs)
8
Analytical Services
10
• HPLC for purity/potency
• Metals
• Microbiology
• Pesticides
• ORAC
Tea Verification Program
13
Research and Development Services
15
• Product development
• Ingredient development
Litigation, Merger & Aquisition Support
17
Tea Ingredients Annual and Tea is “HOT” report
18
Contact ChromaDex
10005 Muirlands Blvd., Suite G
Irvine, CA 92618
Phone: 949-419-0288
Fax: 949-419-0294
Email: [email protected]
www.chromadex.com
Services
3
949-419-0288 | [email protected] | www.chromadex.com
4
Tea Analysis Ave
Tea Analysis Averages
ChromaDex has developed a tea analysis method for the specified compounds below. Several
of the basic tea types have been tested during an internal study which has generated a basic
set of averages for each tea type as an 8 oz. cup of tea. Additional testing programs will create
a viable baseline model for the various tea regions around the world.
Method of Analysis: HPLC with UV detector
Analysis for:
1. Catechins:
a. (+)-Catechin
b. (-)-Epicatechin
c. (-)-Epicatechin gallate
d. (-)-Epigallocatechin
e. (-)-Epigallocatechin gallate
2. Theaflavins:
a. Theaflavin
b. Theaflavin-3-gallate
c. Theaflavin-3’-gallate
d. Theaflavin-3,3’-digallate
3. Xanthines:
a. Caffeine
b. Theophylline
c. Theobromine
Type
White
White Decaf
Green
Green Decaf
Black
Black Decaf
Average Catechins
12.58%
11.93%
11.38%
11.48%
5.50%
4.14%
For further details about the
ChromaDex Tea Services test method,
please Contact our technical sales
department at:
[email protected]
(949) 419-0288
setting THE standard
Average Caffeines
2.71%
0.44%
2.26%
0.48%
3.22%
0.70%
Average Theaflavins
0.10%
0.04%
0.05%
0.05%
0.67%
0.61%
Values are presented in % per 8 oz. cup of tea.
erages
5
949-419-0288 | [email protected] | www.chromadex.com
6
ChromaDex
Products and Se
Understanding ORAC & Folin C
• ORAC and Folin C are nonspecific
anaylsis methods
Folin-C vs. HPLC
18
16
• HPLC IS a specific analysis method
14
12
• ORAC and Folin C values can not be
compared from one product to another.
%
10
8
6
• HPLC values CAN be compared
4
2
0
White
Green
Green
Black
% Polyphenol Content
18
16
14
12
10
%
8
6
4
2
0
Black
• ORAC and Folin C values do not
determine actual content of individual
antioxidants in a tea product
• HPLC values DO determine actual
content of individual antioxidants
• ORAC and Folin C values do not
indicate the biological value of
antioxidants
• HPLC CAN determine the content of
biologically active antioxidants
Ask us about our Single Lab Validation program for tea analysis by HPLC and how you
can be part of setting the tea industry standard for excellence!
For more information: Call (949) 419-0288 or e-mail [email protected]
ervices
7
949-419-0288 | [email protected] | www.chromadex.com
Reference standards an
Tea Related Standards
Main Tea Catechins
Product ID
Product Name
Qty/ Unit
ASB-00003310-010
(+)-CATECHIN (AHP)
10mg
ASB-00003310-025
(+)-CATECHIN (AHP)
25mg
ASB-00005125-005
(-)-EPICATECHIN (AHP)
5mg
ASB-00005125-010
(-)-EPICATECHIN (AHP)
10mg
ASB-00005125-025
(-)-EPICATECHIN (AHP)
25mg
ASB-00005125-050
(-)-EPICATECHIN (AHP)
50mg
ASB-00005135-005
(-)-EPICATECHIN GALLATE (P)
5mg
ASB-00005135-010
(-)-EPICATECHIN GALLATE (P)
10mg
ASB-00005135-025
(-)-EPICATECHIN GALLATE (P)
25mg
ASB-00005145-010
(-)-EPIGALLOCATECHIN (P)
10mg
ASB-00005145-025
(-)-EPIGALLOCATECHIN (P)
25mg
ASB-00005145-050
(-)-EPIGALLOCATECHIN (P)
50mg
ASB-00005150-005
(-)-EPIGALLOCATECHIN GALLATE (P)
5mg
ASB-00005150-010
(-)-EPIGALLOCATECHIN GALLATE (P)
10mg
ASB-00005150-025
(-)-EPIGALLOCATECHIN GALLATE (P)
25mg
ASB-00005150-050
(-)-EPIGALLOCATECHIN GALLATE (P)
50mg
Price*
CALL FOR PRICING
Other Tea Related Catechins
Product ID
Product Name
Qty/ Unit
ASB-00003300-005
(-)-CATECHIN (RG)
5mg
ASB-00003290-010
DL-CATECHIN (SH)
10mg
ASB-00003295-010
DL-CATECHIN (RG)
10mg
ASB-00003295-100
DL-CATECHIN (RG)
100mg
ASB-00003315-005
(-)-CATECHIN GALLATE (SH)
5mg
ASB-00003315-010
(-)-CATECHIN GALLATE (SH)
10mg
ASB-00005152-001
(-)-EPIGALLOCATECHIN GALLATE (RG)
1g
ASB-00005152-005
(-)-EPIGALLOCATECHIN GALLATE (RG)
5g
ASB-00007044-005
(-)-GALLOCATECHIN (SH)
5mg
ASB-00007045-005
(-)-GALLOCATECHIN GALLATE (SH)
5mg
Price*
CALL FOR PRICING
Black Tea Theaflavins
Product ID
Product Name
Qty/ Unit
ASB-00020252-010
THEAFLAVIN (P)
10mg
ASB-00020252-005
THEAFLAVIN (P)
5mg
ASB-00020253-010
THEAFLAVIN-3-GALLATE (SH)
10mg
ASB-00020253-005
THEAFLAVIN-3-GALLATE (SH)
5mg
ASB-00020254-010
THEAFLAVIN-3,3’-DIGALLATE (P)
10mg
ASB-00020254-005
THEAFLAVIN-3,3’-DIGALLATE (P)
5mg
8
949-419-0288 | [email protected] | www.chromadex.com
Price*
CALL FOR PRICING
nd materials (CRMs and BRMs)
Caffeine Related Compounds (Xanthine Alkaloids)
Product ID
Product Name
Qty/ Unit
Price*
ASB-00003032-100
CAFFEINE (P)
100mg
CALL FOR PRICING
ASB-00003032-200
CAFFEINE (P)
200mg
ASB-0020248-100
THEOBROMINE (P)
100mg
ASB-0020248-200
THEOBROMINE (P)
200mg
ASB-0020256-100
THEOPHYLLINE (P)
100mg
ASB-0020256-100
THEOPHYLLINE (P)
100mg
Other Related Tea Compounds of Interest
Product ID
Product Name
Qty/ Unit
ASB-00007040-010
GALLIC ACID (P)
10mg
ASB-00007040-100
GALLIC ACID (P)
100mg
ASB-00007040-001
GALLIC ACID (P)
1g
ASB-00020249-010
L-THEANINE (P)
10mg
ASB-00020249-025
L-THEANINE (P)
25mg
Price*
CALL FOR PRICING
Botanical Reference Materials (BRMs)
Product ID
Product Name
Qty/ Unit
ASB-00030330-005
GREEN TEA LEAF vBRM
5g
Price*
CALL FOR PRICING
Tea Related Analysis Kits
Product ID
Product Name
Qty/ Unit
Price*
KIT-00003286-010
GREEN TEA CATECHIN STANDARDS KIT
5 x 10mg
CALL FOR PRICING
KIT-00003286-025
GREEN TEA CATECHIN STANDARDS KIT
5 x 25mg
KIT-00003285-0HK
GREEN TEA CATECHIN HPLC ANALYSIS KIT
1 kit
KIT-00003285-1HK
GREEN TEA CATECHIN HPLC KIT w/ GRD COL
1 kit
KIT-00020080-010
BLACK TEA THEAFLAVIN STANDARDS KIT
3 x 10mg
KIT-00020080-005
BLACK TEA THEAFLAVIN STANDARDS KIT
3 x 5mg
CALL
BLACK TEA THEAFLAVIN HPLC ANALYSIS KIT
1 Kit
To order
contact a ChromaDex representative today
(949) 419-0288 or [email protected]
Visit www.chromadex.com
9
949-419-0288 | [email protected] | www.chromadex.com
Analytical Servic
Tea Phyto-Constituents
Polyphenol Content for All Camellia sinensis (Black Tea, White Tea, Green Tea, Oolong Tea, Puerh Tea)
Description
Report Type
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
Polyphenol Content (Total) by Folin C
ARS
Polyphenol Content (Total) by Folin C
ATR
CDA-00100224-ARS
Tea for Catechins by HPLC
ARS
CDA-00007010-ARS
Tea for Catechins by HPLC
ATR
CDA-00007010-ATR
CDA-00100224-ATR
Tea for Theaflavines by HPLC
ARS
CDA-00100141-ARS
Tea for Theaflavines by HPLC
ATR
CDA-00100141-ATR
Tea Total Polyphenol Content by HPLC
ARS
CDA-00100231-ARS
Tea Total Polyphenol Content by HPLC
ATR
CDA-00100231-ATR
Caffeine Content (Xanthine Alkaloids)
Description
Report Type
Caffeine (Xanthine Alkaloids) Analysis by HPLC
ARS
Caffeine (Xanthine Alkaloids) Analysis by HPLC
ATR
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00003001-ARS
CDA-00003001-ATR
Tea Identity Testing
Description
Report Type
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Green Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ARS
Green Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ATR
Service Code
CDA-00100004-ARS
CDA-00100004-ATR
Black Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC
ARS
CDA-00100648-ARS
Black Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC
ATR
CDA-00100648-ATR
Rooibos (Aspalathus linearis) Identity Testing by HP-TLC
ARS
CDA-00100649-ARS
Rooibos (Aspalathus linearis) Identity Testing by HP-TLC
ATR
CDA-00100649-ATR
Tea Identity Testing by Bioluminex
ARS
CDA-00100218-ARS
Tea Identity Testing by Bioluminex
ATR
CDA-00100218-ATR
Contaminants Testing
Microbiological Testing
Description
Report Type
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
FULL MICROBIOLOGICAL PANEL #1
ARS
FULL MICROBIOLOGICAL PANEL #2
ARS
CDA-00100254-ARS
FULL MICROBIOLOGICAL PANEL #3
ARS
CDA-00100620-ARS
FULL MICROBIOLOGICAL PANEL #4
ARS
CDA-00100621-ARS
CDA-00100619-ARS
TOTAL AEROBIC COUNT
ARS
CDA-00100087-ARS
TOTAL YEAST AND MOLD PANEL
ARS
CDA-00100251-ARS
10
949-419-0288 | [email protected] | www.chromadex.com
ces - Tea Testing
Contaminants Testing
Microbiological Testing
Description
Report Type
COLIFORM
ARS
E. COLI
ARS
ENTEROBACTERIACEAE
ARS
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00100252-ARS
CDA-00100618-ARS
CDA-00100347-ARS
PSEUDOMONAS
ARS
CDA-00100257-ARS
LISTERIA
ARS
CDA-00100087-ARS
SALMONELLA
ARS
CDA-00100255-ARS
STAPHYLOCOCCUS AUREUS
ARS
CDA-00100253-ARS
E. COLI 0157:H7
ARS
CDA-00100348-ARS
Metals
Description
Report Type
RCRA 8 Metals Panel by ICP
ARS
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00100314-ARS
Metal Testing: Arsenic analysis by ICP
ARS
Metal Testing: Cadmium analysis by ICP
ARS
CDA-00100502-ARS
CDA-00100501-ARS
Metal Testing: Chromium analysis by ICP
ARS
CDA-00100503-ARS
Metal Testing: Copper analysis by ICP
ARS
CDA-00100550-ARS
Metal Testing: Iron analysis by ICP
ARS
CDA-00100547-ARS
Metal Testing: Lead analysis by ICP
ARS
CDA-00100505-ARS
Metal Testing: Magnesium analysis by ICP
ARS
CDA-00100506-ARS
Metal Testing: Manganese analysis by ICP
ARS
CDA-00100548-ARS
Metal Testing: Mercury analysis by ICP
ARS
CDA-00100504-ARS
Metal Testing: Molybdenum analysis by ICP
ARS
CDA-00100549-ARS
Metal Testing: Potassium analysis by ICP
ARS
CDA-00100509-ARS
Metal Testing: Selenium analysis by ICP
ARS
CDA-00100507-ARS
Metal Testing: Zinc analysis by ICP
ARS
CDA-00100508-ARS
Pesticides
Description
Report Type
Pesticide Screening Panel CDFA
ARS
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00100316-ARS
ORAC/Biological Assays
Description
Report Type
ORAC Hydrophyllic and Lipophyllic Assay
ATR
Bioactivity Fingerprint Testing by Bioluminex
ARS
Bioactivity Fingerprint Testing by Bioluminex
ATR
1 Sample
2-4 Samples
5-9 Samples
CALL FOR PRICING
10+ Samples
Service Code
CDA-00100236-ATR
CDA-00100218-ARS
CDA-00100218-ATR
11
949-419-0288 | [email protected] | www.chromadex.com
Analytical Services - Tea Testing
Other Tea Nutrient Testing
Amino Acids
Description
Report Type
L-Theanine Analysis by HPLC
ARS
L-Theanine Analysis by HPLC
ATR
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00019008-ARS
CDA-00019008-ATR
Note: Other amino acids are available upon request
Vitamins
Description
Report Type
Vitamin A (Retinol) by HPLC
ARS
Vitamin A (Retinol) by HPLC
ATR
Vitamin B Panel by HPLC
ARS
1 Sample
2-4 Samples
5-9 Samples
10+ Samples
CALL FOR PRICING
Service Code
CDA-00100269-ARS
CDA-00100269-ATR
CDA-00100265-ARS
Vitamin B Panel by HPLC
ATR
CDA-00100265-ATR
Vitamin B1(Thiamine) by HPLC
ARS
CDA-00100260-ARS
Vitamin B1(Thiamine) by HPLC
ATR
CDA-00100260-ATR
Vitamin B12 (Cyanocobalamin) by HPLC
ARS
CDA-00100185-ARS
Vitamin B12 (Cyanocobalamin) by HPLC
ATR
CDA-00100185-ATR
Vitamin B12 Analysis by HPLC
ATR
CDA-00100186-ATR
Vitamin B2 (Riboflavin) by HPLC
ARS
CDA-00100373-ARS
Vitamin B2 (Riboflavin) by HPLC
ATR
CDA-00100373-ATR
Vitamin B3 (Niacinamide) by HPLC
ARS
CDA-00100322-ARS
Vitamin B3 (Niacinamide) by HPLC
ATR
CDA-00100322-ATR
Vitamin B5 (Calcium Pantothenate) by HPLC
ARS
CDA-00100374-ARS
Vitamin B5 (Calcium Pantothenate) by HPLC
ATR
CDA-00100374-ATR
Vitamin B6 (Pyridoxine) by HPLC
ARS
CDA-00100375-ARS
Vitamin B6 (Pyridoxine) by HPLC
ATR
CDA-00100375-ATR
Vitamin C (Ascorbic Acid) by HPLC
ARS
CDA-00021009-ARS
Vitamin C (Ascorbic Acid) by HPLC
ATR
CDA-00021009-ATR
Vitamin C (Ascorbic Acid) Full Panel by HPLC
ARS
CDA-00100510-ARS
Vitamin D2 (Ergocalciferol - formula) by HPLC
ARS
CDA-00100377-ARS
Vitamin D2 (Ergocalciferol - formula) by HPLC
ATR
CDA-00100377-ATR
Vitamin D3 (Cholecalciferol - formula) by HPLC
ARS
CDA-00100378-ARS
Vitamin D3 (Cholecalciferol - formula) by HPLC
ATR
CDA-00100378-ATR
Vitamin E (Tocopherols) by HPLC
ARS
CDA-00100379-ARS
Vitamin E (Tocopherols) by HPLC
ATR
CDA-00100379-ATR
Tocopherol (Vitamin E) by HPLC
ARS
CDA-00100295-ARS
Tocopherol (Vitamin E) by HPLC
ATR
CDA-00100295-ATR
Folic Acid (Vitamin M) (w/sample clean up) by HPLC
ARS
CDA-00100267-ARS
Folic Acid (Vitamin M) (w/sample clean up) by HPLC
ATR
CDA-00100267-ATR
Biotin - formula (w/sample clean up) by HPLC
ARS
CDA-00100372-ARS
Biotin - formula (w/sample clean up) by HPLC
ATR
CDA-00100372-ATR
12
949-419-0288 | [email protected] | www.chromadex.com
Tea Verification Programs
ChromaDex will soon offer a comprehensive range of verification services, where tea related
businesses can send samples of their tea products of several different types for origin, purity, and
potency verification.
ChromaDex will start with the launch of “Polyphenol Content Verified” and “Decaffination Verified.”
POLYPHENOL CONTENT
VERIFIED
DECAFFEINATION
VERIFIED
After the launch of the first two verification services above we will launch programs including “Verified
Contaminant Free” to help companies build confidence in consumers that their products are free of
heavy metals, pesticides and microbiological contamination. ChromaDex is also working on a
program to verify the geo-origin of different types of tea.
CONTAMINANT FREE
VERIFIED
IDENTITY VERIFIED
For more information about these new verification programs, or if you would like to become part of the
ChromaDex Verification Services programs please contact us at 949-419-0288.
13
949-419-0288 | [email protected] | www.chromadex.com
14
Research
and Developmen
Research and Development Services
The ChromaDex Tea Services offers turnkey
analytical and R&D support resources for virtually
any type of tea (or ‘herbal tea’) ingredient, product or
technology. Our team of experts brings decades of
both analytical sciences and tea industry experience
to all of your projects. From simple product R&D
support to complex initiatives, ChromaDex provides
an unparalleled range of tea ingredient (raw or
processed raw materials), products (finished goods)
and technology (processing, brewing, dispensing)
R&D services to clients located all over the world.
Our Tea Services include constituent isolation,
product formulation (original and updates) and
process development, through bioassay services
and comprehensive consulting. All ChromaDex
Tea Services are centered on our successful client
service models used to service clients in the natural
products industry.
• Flavor Support: Simple and complex flavoring
of dry, liquid and other tea materials, novel
flavors (natural, organic applicable, artificial)
• Specimen Verification, Botanical Reference
Standards (Tea & Herbal Tea)
• Archive Libraries, Origin Authenticity
Documentation, Origin Characterization
Profiling
• Quality Assurance Systems, Labeling Programs
& Testing for Individual Products, Trade
Associations, Producing Origins
• Ideation: Creative concepts (tea products or
targeted demographics, niche segments,
product / brand revitalization
• Product formulation, updates and
troubleshooting
• Organoleptic (Sensory) Assessments: Blind
‘cupping’ assessments by skilled tea industry
veterans, formal tasting panels and product
profiling
• Product Assessments: Competitor
differentiation and positioning analysis
nt Services
949-419-0288 | [email protected] | www.chromadex.com
15
16
Litigation,
Merger & Aquisit
Litigation, Merger & Aquisition Support
Whether you are utilizing tea within a beverage, dietary supplement, food, cosmetic or other application, manufacturing processes, formulations and marketing materials periodically need to be assessed
for quality and marketing claims. ChromaDex can offer true end-to-end analytical services to enhance
litigation prevention as well as support companies during litigation.
ChromaDex has performed litigation support such as:
•
Productcontentandlabelclaims
•
Productadulteration
•
Expertwitnessforanalyticalorqualityissues
•
Falseadvertisingclaimsrelatedtoproductcontent
•
Rawmaterial,contractmanufacturingdisputes
•
Patentinfringement
•
Mediationwhereanalyticaldataisinquestion
Merger & Aquisition Services
•
Technologytransfersupport
•
Merger&Acquisitionduediligencesupport(materials,products,technologies)
•
Producttesting,patentsearchesandexpertopinionpriortoMerger&Acquisitionclosure
•
Activetea-focusedMerger&Acquisition,tech-transferreferralsandintroductions
Risk Managment
• Insurance rate reduction
• Reduce potential litigation exposure
tion Support
949-419-0288 | [email protected] | www.chromadex.com
17
Tea Ingredients Annual™ 2008
TEA INGREDIENTS ANNUAL™ 2008
TheÊ UltimateÊ TeaÊ ProductsÊ IngredientsÊ Directoryª
Insider Sources: Extracts, Concentrates, Essences, Flavorings,
Nutraceutical & Functional Additives
Analytical Testing Laboratories with Tea-Specific Services
Resources for manufacturers, formulators, food technologists:
Beverage, Skincare, Pharma & More
Tools for Navigating An Emerging Marketplace
...& More
Publishing Relevant Tea Industry Information, Resources & Insights Since 1995
www.teareport.com
Denver, Colorado / USA
Tea Ingredients Annual™ 2008 Tea-based ingredients are becoming the number one choice for adding
innovation and health to diverse consumer products. TIA 2008 is the ultimate source-book for companies
manufacturing products containing tea-based ingredients; a must-have resource for formulators, food
technologists and consumer product scientists. TIA lists ingredient suppliers (tea and ‘herbal’ tea),
analytical laboratories and detailed information on scientifically assessing tea-based ingredients.
Visit www.teareport.com to p
18
Tea is “HOT” Report®
Specialty Tea Is “Hot” Report® 6th Edition
provides a vital snapshot of the US specialty tea
industry and key market catalysts, as well as,
tea trends, fads circa 2006-2008. Includes a
retailer pricing (products) survey and supply chain
quantification. Find information on the art and
science of professional tea tasting, the aroma of
tea, Fair Trade and specialty tea value propositions,
insights and opinions. Learn how to buy, analyze
and store tea from the world’s leading experts.
Tea Is “Hot” Report® 5th Edition provides a
vital snapshot of the US specialty tea industry, circa
the early 2000s. Including close-up coverage on
Decaffeinated tea, Organic, Fair Trade, Chai, Herb
“Tea” and Yerba Maté and information on key tea
producing origins, with commentary, data and
profiles. This edition provides the very first retailer
quantification estimates, as well as coverage
on tea extracts, tea and health and other nonbeverage tea topics not covered anywhere else.
purchase these publications
19
www.chromadex.com
10005 Muirlands Blvd., Suite G
Irvine, CA 92618
RETURN SERVICE REQUESTED
04/2010