olloo/oe
Transcription
olloo/oe
olloo/oe i11H114.11.S11Th a Diseases of ferrets 217,'''Ttnnf Abstract : Prayot Tanticharoenyos. 1995. Diseases of ferrets. Thai J Hlth Resch 9(2) : 133-138 Ferrets have also been used in research studies involving anatomy, bacteriology, mycology, behavior, and hematology amongst others. The ferret will continue to evolve as an important animal model for biomedical research as judged from the many important advancements made by their use in the past. As other laboratory animals, ferret can get sick with viral, bacterial, fungal and parasitic diseases. Some diseases in dogs and cats can be transmitted to ferrets in case of they are housed in mixed animal colonies. Key words : Ferrets, diseases ; Etiology, virus, bacteria, fungi, parasites 1.1n61110 : 2538. Ilf1116111^1041111. 113d1' WJ illt111111141111111NY9ti 9(2): 133-138 Mit-inlialefi gni ganlsdnEtiiv-titiltntrun7u3frm, 1tuniiilu3ntn Iii8133nu7 honjoidna4Toi-in3nn7 oiloiisnQ:,-17417nrInd°361191'0 7117nfinithaaatimr-iudnInnoov illu3d,i84f1-11 n773avo43ntnn 1711114311'1161111P100 ∎1611 IIIIIvnii Tninianano-inuolioomnfinnli-nlei ififyolndo-hfilnihni'lh ad-) 7 ul inisii7no )vallIllta1117 -7nhlf7nv-intila777'n 1-70117421Q011194q0111.0:.111.13 o wiindam 61d1f1811 l iniefon, tiro ino:il7in ilv7711nT7411011151140-HILItlia913'nowniQoatliaufal Iso ; 0711191, Iasi, ituonau, S7, ilfdo *an7v1i3o1Iinulnlawfn77unnif vrt7o4nsnim177nt11du ns ‘unrunfnms 10330 Institute of Health Research, Chulalongkorn University, Bangkok 10330. / /0)3/3 2' 134 viliFilqinjug 1.111141 ilAi'119100111411 0 "11^10i'1511" 1 t10 -31110161.10 -15)inallii0ifliffflif115111AllriEd191011.1 VTA'Iti19111'11411`111 1111 tilf1111.1r116411140151fil.491)061,141149141191001 10 oCA'15i1,11tifiNMIDAf11111fillm1-111i1titlj fl 111 ' A 0159,1wrpnivuo-uninFrvillthloqvfalulhn-n5 15111o9d isI gialtaiiviilfifitivotisnli oti 40 -114 11,1f1561/1:111401,114149J11flall 0E11115119111J 1910111 GUEJlEITI4 1`1,4 6110111511101,0,VM 11i11AITtlIf194I5,11gE1,1 1111tlliti1uw9Jn15t9N1n19i9Vlv9i "dniturldnvilui5Atlovril4funi5Gificrsvila4t% tMil lijo crth (canine distemper) 5:,'Un101171160614I5t1f101091'04114001411i141 (21 1U) 1191 f1/1111nA'91 -A1411111111:1414 11:1100B191-iO41141,ifi014 ili Vra1141151110141111t11101014011110nlit111411 '3011; timinfitililfrini5InInfiaarmrcwiDld lin4uoin151111fifinfiraniaolvala6.5 cntrionloitfh4Mia 110151191111f15t;91110611111151 tin315:4tharrimilurpnioluilln-amsth'o4fIrilviotfinnu 50% alfmcvnlfinn 1.15nowilottailitflonis' q qt-15t:mloalti'En4 0011111M1 (melena) 1110011115 i119111091 11141J31 -A11199111711 0 ,111a:',111111q91i -NYT,If(0141 ,111111011 20% (symmetrical alopecia) 01015111,11111V:',1151i1111'01141i.10 hematocrit 50,000/ id hematocrit 09191111 - 2l 90 614 tta:vvilotnAo ,‘,'16911115dni101411A'IVUOli5f1I01191TIAIS174q ullgillf411i11 1111191rd091119111111110tIfliflai 1115i '011101f11,110110t41C14 1114 I 141114t9110 0151104614041101011 11,111119911 I9100159T9li's1111110:-A1911t100t11110AVI)?1101 q 6-8 1'9'1014 untlittlyn561114Tioasniloaaln1514 1111&1 10 chorionic gonadotrophin 61101011 6111.4191 100 IU flfslaitY) 1411113J11101141111519Jl4A9114 WA1J1111-14011,111191'ilf115910110,1$11 11M,Aill111 ,15f1151fiLli9V110191'11110111J91111114 20-25 214 ttc1: 9 d;0,100, 1145t:EI: anestrous tril cutial 45-50 1f10110151111 megestrol acetate riLtmviviisivflallait-Tv uonuniT torrimilvti4tmluivil f1151fhlrim illtflon 4 kialtm apiastic anemia iti gi-ltiluValith0 1140i'151191'11iltrarvi'0,11110111141J1f111910111511191 eclamptogenic toxemia 115101114015&1110%0411^M151 r1Tifirf11119-19111 1111011110 thlrf 14051 0151,N1N0lili01141591Dl5111110110t11401011 1. lurtillmwilTa 1.1 i5f1141X0CflIst1 (canine distemper) triD5l5T1V1U0tTlfii91l5f1141%90411111T1f1 1,1>M11&1511115 91101,91011155n11919111Jb551JI1F1 U',0 .,, 1711191'1 6U0slilf19111.11.11191t0 q 5:,-11 -ill 7-10 ill 01f115131Th5f1C110 0onunU1tta99jottio4u 9119ila1tart411411.1A14 416 910S111114 914491f0wd191'011110n15rminv1141i 44rV1l9if111111ttM;9113J1J1410 hyperkeratosis rff111411101 Ita,'., ,'911EA0113011,411.J5:,'3J1ild 14 1110011115 1717(1411111filalt 0111001J1411140 ,11111101 . This 9 91TICO 2 135 11 .0. 2538 '640 modified live virus (MLV) 611411 MID 4̀1,51111,1t1151A1J111591 -5AVI5f111117(0 I 1fl fiVintlii (chick embryo) ellon11141(4 -auf,IDliloleasliVilll itiCii5i11411411IT'Utii0 MLV 11191)win 1 115 .1141Inilutrloi' tvn 1,11fltIAITtAt1sniflrffieUlli Do rlai' 151/ 11j 111=1-11111141,11510 - nAithip rhm itrific h t4a9n01111111405t-ibilivtaila trlDi"1511f1151A111411441J111f11110 Olq 6-8 A1191111 (111,111E11111 (Anon, 1984) uan-ii 8-10 if'do-ri) fi&autt5nlapaiq 4-5 A1lATY1 11A:;f1'15115,'41.1411,161H111Gf15111511 2 1i1.191114 (Goodwin (19...) 111&141JfiVID1111DDlq , 2-3 lJ 117 a1 f1 J11J^ifi^ll 9-12 f'fthilli) 1111D111A 014/1ili141J6WiDli101 `4,1f115@liflif`1111a.1151,1I5f1111/111 liT-45fillivTorphrnm5m11111;191nAloi't51114'untitu g ul9, `614110a8,1 1.2 I5f1fAill TIT (rabies) 15flom tvloi"1,5111-wiafnAvi5tritililll‘tnii ad11 A'srifts `ii91-111E11 11f1113Jilif.11-14D491ifli11 11 finl 5 mA' 1115:Iniirmlurloi tra d itrit tilDltin.d5inqiiiiaq5luviii4 1454 111409110il ltaY-i-113.1iin114nIni1 1f11,1i5fliiii 111111T1 11151:A0 1t1 modified live rabies vaccine 11.111i14114 1.3 i1141141110IfllIAIll eds9111J91M11100fl ,111.1113T) (feline panleukopenia) 11191,'1111151141111J1111.1 llillf1111.1i11111-14D40 -541 ,i54 111104611I5fld Wif1114014 ,1r7,111191 -il -ifltuvyloaa4014;01')Tri' feline pan- leukopenia 14111111^i e151511 d11.115fl ymiltrio cerebellar hypoplasia 1911141 IllflifflIt111110iflcifil-11101f511,1 I5fidt-iutviDlt5v 11111041(1 1.4 1411 -5411114,4111 (human influenza) W101151111 WiDf1157101401-1Tr(119111-TC1111111110,1f11411d1E1 Isrio 5,'otin-iovisl allni 9 11D111/10i1111 01Tviillilumniuoiniltiutt5n suDli504TTorph14 Ittff, 1115411111M5 -1011 -111DtillE114'1D ,19111.1t551J9S1F1111f1111 4 - 5 71.4 1.5 Aleutian disease (Plasmacytosis) ilf15t,'1110`1116911111i14 (mink) id-Swwialnellivlai"t5T1 1Mam1111-11.1 41161,115f1NUMNIIIIIA TU1111111Difi'Vli.V.1ADIJI1151A1AND1,111131,1 111,1f11.101u101fl151/115t,'11111.15,f(111111A9110 6\111111 Tf141-1111D1115T111:1414NflvillffIJI14 1111V15 "1 Tiorruniirnm,11,4o-51,11.Amp)intni-urn:;u4-)tiliaiimln-ii Iiii0 110 2% gluteraldehyde, 2% formaldehyde fla,'01i1T1.1f1101 halogen V(11.115(10f111/11-111,5,1116.11-1Trf14 ili5f11(11,111frritainIfil' Aii11^18 11511101rill.1141111115T10d04 1414 Pseudorabies, infectious bovine rhinotracheitis fiTh feline leukemia virus (FeLV) iti0hlai05151114 119101tTlYWnlalifilii31005r1Olial 41011f11-114i111^10i"151/ill retrovirus Ofi ife lfi0111111A cross react FeLV tlf1f1151,10dDIJ niu mink virus enteritis, canine hepatitis, feline rhinotracheitis '1110 feline calicivirus 11W1,'1, 1,111101.4ilfill canine parvovirus 4119 s- A A 2. Ilta11110111111JallEJ 2.1 D111151f.114111111C1011-1115•1111f1 (botulism) 16M,1151tffl51Nli botulin T11111f0 Clostridium botulinum , 1,1^1011,111111.1114flallviOd15 botulin %fi g A B 11ViVet 11.11111710 C Dti").115fUllt,'111 triolltpral mlosAaini5 11101111f113115f1110,161 ,110tifil6111,11d1011411V1411(151141,1filiC1014 0114151J.14 11111I ,A111-11fi,191111Ufl Oldf(15i111 botulin 0,4 9,,=. 136 dultrull (tuberculosis) lvlai'l5T11'39i0f115F101.111 0 Mycobacterium tuberculosis 111101411111491 2.2 9111 W111111 1fin5tilatLatfi14 0111110113,6i144M1411"i1191141,1 4W111011I5f1 5:1411541141 iilliflitflati101f115 G10/111114 01i101f1116111110110411119-113J3J1 tilr111,115ilfiSirliwiamiltvia044-16 -114 (mesenteric lymph nodes) f1111112 flilliSfid lY151`.',11^10i'l5T1F145filirilltillitifillY1111.14011,115 iia:,'9-1011111111h11149;0111 1 0 1 9104 1.140i14111 lft19111 1 40111151104f114 lifahillii141„19101104140 M.tuberculosis 2.3 110451•9 (diarrhea) 01f1151104i'Ar(13.11501F1061J11^10i "151,14105401401J1f1IJ -10 1oti11i 11511J?f11Y10 -111'0111111101illYillifl1041,1 I501146ntaumniO4401,11001fliff011q11 01f11AU1FINKLI ihr,f101J41014104i1,1111,1CA091 011115LifltOltliti 3-4 ill 114f1561111 014 01f11511'04i1101%fhl Ionfilmatnnomi5641fiminii Will iigriT,'„'NDIJitillaltLatfitivAluiv 1 l'iott f115i'f11116'1111 -101T1111114410 Neomycin 111110 10-20 9.111./1111. Proliferative colitis fiOlt4lii9111'04illii17441111i11.1411,11iimpuhd000amill ui 00a1 li3/41D011115 1.71-1111.1141 011111 (Olflblo) v1nn151Yvin ch05-miu Campylobacter 111,1)itlitlff114, 01113f11 910111151(114f1C1frdfAlltt r(11J150lItlfl1111140 Campylo- bacter fetus subspecies jejuni 61% 11101.1t111111,t11 1140'1151,111a1£19i1sIfIllt:',ItIATIOsli14 A'snfluvlai'tly(44riJuviittlutisoimni, 111114 erythromycin Ynsrdin campylobacteriosis 111014 , 2.4 14-11-11J6111?11.1 (mastitis) 11421411111114;0 hemolytic Escherichia coli 'IfIlvlOi"1511`191J9103J111143J 6fuvulta:i,4 1i10911U 410 011,15,11n111.1 illgt14 9,, 110L I9101J' aini5111 0iO3,11111,1111111111D:,11.1'Atlila ionYntiwri9iowuminffiau 11154-llihtt 111119'111111.11 ; gentamicin 3 1111. 1007 (ampicillin 10 Ilfl./11t1. 111114r11141-14 ; gentamicin &1111-114-mirri6t-firrti) 11114cia n159imaiviouii6furrintanilothin'Sliiulaan IL4-3i'fiEn91)-)tAihut,14 w,.,14pia11ntu , 2.5 015 91A IISDlIJVIlf141111£114011 Il (superficial infections) A'falill:t,'1151,1114191U14110 0V11111-10liNa illillthalvionso Staphylococci, 6916115.1',11i141-1V(111^114 Corynebacteria Streptococci uNallni&nnitittio .uulnlitUflatiM'f15111 ttronia-nnnwil9Mlutn 111 imz11155Z111011140100fl u114714 t1111111111 streptomycin 114111-1101A C T4,1644141.114tTIJI1410 1151,1 A lIfillif1gt1f1111011 i5f1111JV(11,11q114051N1f1 151141111111 (ringworm) V111,115aAvi011164,11113^10i'151,11111.11J1 21 s)s) subclinic Ilf0511.11{11-1110Aluni5lTinu griseofulvin 25 Itfl./fItl. d A qv1,100111111101111, 61f05 -1T1111lVilflOt5f1 actinomycosis cryptococcosis Turiitilotlndiiivi irlai't5virnuiln`iioihavrritihniurriltuDnanikilalutil'o et .4 9) A _ 2 9_3_, M11 T 910 4.1 IStlf10 (scabies) 1.60TH-191l Sarcoptes scabiei lltIlflV1111,11117-1111P1411:1',Y1S1VI11L11 W i 9 '91111il 2 lIntali1'1041511 137 11.11. 2538 ni'vu-nntanilurfneloursm 6ffirruvill1Jot1115141151 cj li-aluvialvili cti'vnuothArriu (euthanasia) 1111AVICIOLWIlltik1119101.01Vir,1410 0011 4) 111141001Y11911f111Jvtlll 7150 benzyl benzoate 1_1VV:thiiitYnititriLia-mtA0 ivermectin 4.2 I5f11111D111101i1T -fk (dirofilariasis) LAO 11511V11/115A1145WY1110141101.11"1"11V140111 b553J911` ii11111111^101151'111111401VVIElli Dirofilaria immitis 6 - 10 G1'111411'11 )I Gufutt Al 1 flYIDIAELI iluovvitniif-AvutolvID11511 rnm5t-linE114Na;141U avermectins 4.3 191101-11101illin5ztrilr.6114 (gastrointestinal helminths) WIDi'ISTAIII5f1111101,11101111,1 115:,1111`.','S1104)M1Ulfiri91 19;11 11UliV1c1fI0IJ 14/Lifi Toxascaris leonina rh14VitligNIMILIMVinT611013,1i1 111114-) Tif115TnInvitniniululiltrIali519 5104111 f115V151TNpalL1011159151q115:,' brrio'illni5i114fTutan 4.4 1511411 (ear mite) 1146115111W10(11591911511tyfiltri q ufl Otodectes cynotis ci1;41,i11141i0t1 Sf11J1UTa ti01N rotenone Y956 pyrethrin 1_111TItTf1141144161115 ivermectin 4.5 1.15RA11 1 C141516411( 141111 111TO (flea - Ctenocephalides spp.) 111401.41161i1MTH1461,1 11101 Filaroides spp. It)SLi ciTisCtolIVIWA ‘A Giardia sporozoan 1411f1 Toxoplasma ti11474 c I lfltflU1111.11140A0f1 ihltJA11111151691i5t111,1040f1911-11,04111LADfi5V1M1UISt1 011741 Lymphosarcoma, mammary gland cystadenocarcinoma, non-aggressive dermal mast cell tumors, cutaneous squamous cell carcinomas, ovarian leiomyomas and ovarian smooth muscle hyperplasia, ovarian thecomas and a pancreatic adenocarcinoma 11i 14 15f1414 (miscellaneous medical problems) 191111i urolithiasis, biotin deficiency, hemivertebrae, vertebral fractures, myelitis, hematomyelia, intervertebral disk disease liar, zinc toxicity 100d15111n1011111516t1014 Anon. 1984. Guide to the care and use of experimental animal, Vol 2. Canada Council of Animal Care. pp. 83-87. Bernard SL, Leathers CW, Brobst DF, et al. 1983. Estrogen-induced bone marrow depression in ferrets. Am J Vet Res 44 : 657-661. Blair LS and Campbell WC. 1980. Suppression of maturation of Dirofilaria immitis in Mustela putorius furo by single dose of ivermectin. J Parasitol 66 : 691-692. Blair LS, Williams E, and Ewanciw DV. 1982. Efficacy of ivermectin against third stage Dirofilaria immitis larvae in ferrets and dogs. Res Vet Sci 33 : 386-387. Buckwell AC. 1981. Persistent oestrus in ferrets. Vet Rec 109 : 88. Carpenter JW, Davidson JP, Novilla MN, et al. 1980. Metastatic papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. J Wildt Dis 16 : 587-592. 138 1.112Intil Alat6funo 111d117v 11111111f1101401I1111116 Chesterman FC and Pomerance A. 1965. Spontaneous neoplasm in ferrets and polecats. J Pathol Bacteriol 89 : 529-533. Cotchin E. 1980. Smooth muscle hyperplasia and neoplasia in the ovaries of domestic ferrets (Mustela putorius furo). J Pathol 130 : 169-172. Egerton JR, Birnbaum J, Blair LS, et al. 1980. 22, 23 Dyhydroavermectin B 1 , a new broad spectrum antiparasitic agent. Br Vet J 136 : 88-97. Fox JG, Murphy JC, Ackerman JI, et al. 1982. Proliferative colitis in ferrets. Am J Vet Res. 43 : 858-864. Fox JG, Ackerman JI, and Newcomer CE. 1983. Ferret as a potential reservoir for human Campylobacteriosis. Am J Vet Res 44 : 1049-1052. Frederick MA. 1981. Intervertebral disc syndrome in a domestic ferret. VM/SAC 76 : 835. Goodwin BS, Jr.19.... Ferrets in biomedical research (monograph). Lt Col, VC, US Army. Special Assistant for Veterinary Medicine. Naval Medical Research and Development Command, Bethesda, Maryland, USA. pp 1-8. Hagen KW and Gorham JR. 1972. Dermatomycosis in fur animals : Chinchilla, ferret, mink and rabbit. VM/SAC 67 : 43. Hammond J, Jr and Chesterman FC. 1976. The ferret. In : The UFAW handbook on the care and management of laboratory animals (5 th Ed). Churchill Livingtone, London, UK. pp 357-366. Johnson RH, Margolis G, and Kilham L. 1967. Identity of feline ataxia virus with panleukopenia virus. Nature 214 : 175. Kociba GJ and Caputo CA. 1981. Aplastic anemia associated with estrus in pet ferrets. JAVMA 178 : 1293-1294. Liberson AJ, Newcomer CE, Ackerman JI, et al. 1983. Mastitis caused by hemolytic Escherichia coli in the ferret. JAVMA 183 : 1179-1181. Moody KD, Bowman TA, and Lang CM. 1985. Laboratory management of the ferret for biomedical research. Laboratory Animal Science, Vol 35 (3) : 272-279. Nguyen HT, Moreland AF, and Shields RP. 1979. Urolithiasis in ferrets (Mustela putorius). Lab Anim Sci 29 : 243-245. Ryland LM and Gorham JR. 1978. The ferret and its diseases. J Am Vet Med Assoc 173: 1154. Ryland LM, Bernard SL, and Gorham JR. 1983. A clinical guide to pet ferret. Compendium on Continuing Education for the Practicing Veterinarian 5 : 25-32. Skulski G and Symmers W St C. 1954. Actinomycosis and torulosis in the ferret. J Comp Pathol 64 : 306-311. Smith PC. 1978. Experimental infectious bovine rhinotracheitis virus infections of English ferrets (Mustela putorius furo L). Am J Vet Res. 43 : 858-864. Straube EF, Schuster NH, and Sinclair AJ. 1980. Zinc toxicity in the ferret. J Comp Pathol 90 : 355-361. Straube EF and Walden NB. 1981. Zinc poisoning in ferrets (Mustela putorius furo). Lab Anim 15 : 45-47. Symmers SC and Thomson APD. 1953. Multiple carcinomata and focal mast cell accumulations in the skin of a ferret (Mustela furo L.) With a note on other tumors in ferrets. J Pathol Bacteriol 65 : 481-492.