Solutions for CRRT Comparisons March 2009

Solutions for CRRT Comparisons March 2009
Home: Critical Care: Products: Fluids
NxStage prepackaged fluids for acute renal care
NxStage provides a full range of easy-to-use, convenient and economical sterile dialysate fluids that
simplify the delivery of intensive care dialysis. NxStage PureFlow™ prepackaged solutions offer
significant advantages:
They are available with bicarbonate or lactate buffers, giving you treatment options.
NxStage PureFlow Solutions ensure fluid quality, with potential clinical benefits. They meet
or exceed AAMI, USP, and European Pharmacopoeia standards. Products are terminally sterilized
and pyrogen-free (< 0.25 EU/mL).
They eliminate the need to install large, complex water purification systems.
They allow for simple dosing and usage, reducing workload on busy ICU staff.
Convenient 5-liter bags minimize interventions.
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Your choice of solution buffer:
Bicarbonate—The body’s natural buffer; may be suitable for patients
with lactic acidosis and/or liver failure. The two-compartment bag with
unique peel-seam interface simplifies preparation and mixing.
Lactate—Simplest, most economical solution; no mixing required.
Effectiveness for most patients is well-supported in clinical literature.
NxStage PureFlow Solutions for use in acute hemodialysis with the
NxStage System One include:
Constituent
(mEq/L)
Lactate Buffer
Bicarbonate Buffer
RFP-204 RFP-205 RFP-207 RFP-400 RFP-401 RFP-402 RFP-453 RFP-454
Lactate
40
35
45
0
0
0
0
0
Bicarbonate
0
0
0
35
35
35
25
25
Potassium
1
3
1
2
4
0
2
4
Sodium
140
140
140
140
140
140
130
130
Calcium
3
3
3
3
3
3
0
0
Magnesium
1
1
1
1
1
1
1.5
1.5
Chloride
105
112
100
111
113
109
108.5
110.5
Glucose
(mg/dL)
100
100
100
100
100
100
100
100
NxStage PureFlow Solutions are indicated for use with renal replacement systems that utilize sterile
premixed dialysate. They are not indicated for direct infusion.
FLEXIBLE • SAFE • PROTOCOL NEUTRAL
Normocarb HF is a pharmaceutical-grade,
clinically-tested, FDA approved, protocol-neutral
hemofiltration solution for CRRT.
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NORMOCARB HF™ Formulation
NORMOCARB HF™ is a clear, sterile, nonpyrogenic, electrolyte concentrate used in Continuous Renal
Replacement Therapy (CRRT) as a replacement solution in hemofiltration or hemodiafiltration.
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Composition
Undiluted NORMOCARB HF™ 25 contains 90.73 g/L sodium chloride (NaCl), 2.06 g/L magnesium
chloride hexahydrate (MgCl2•6H2O) and 28.35 g/L sodium bicarbonate (NaHCO3) in water for injection.
Undiluted NORMOCARB HF™ 35 contains 82.84 g/L sodium chloride (NaCl), 2.06 g/L magnesium
chloride hexahydrate (MgCl2•6H2O) and 39.70 g/L sodium bicarbonate (NaHCO3) in water for injection.
Diluted NORMOCARB HF™ 25 or NORMOCARB HF™ 35 solutions when prepared as directed, contain
the following:
NC 25 HF
NC 35 HF
mEq/L
mEq/L
Quote
"Normocarb HF
from the
SODIUM (Na)
140.0
140.0
pharmacy
eliminates
MAGNESIUM (Mg)
1.5
1.5
concerns I have
about bedside
preparation and
CHLORIDE (Cl)
116.5
106.5
solution
selection. In our
BICARBONATE (HCO3)
25.0
35.0
critical-care
environment, we
need to put
POTASSIUM (K)
0
0
maximum focus
on patient care,
and on
CALCIUM (Ca)
0
0
eliminating
errors.
pH
8.55 +/- 0.25
8.55 +/- 0.25
Normocarb HF
provides me with
a safe, flexible
solution that I know I can trust."
Copyright © 2007 Dialysis Solutions Inc. | All Rights Reserved
PrismaSate® Dialysate
Easy-to-use dialysate formulas specifically designed for critical care.
PrismaSate® dialysate offers six formulas specifically designed for
Continuous Renal Replacement Therapy (CRRT). These dialysate
formulas save time and expense and provide unmatched prescription
flexibility. PrismaSate features:
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Sterile, bicarbonate-based solution better controls and
corrects acidosis
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Each 5-liter, two-compartment bag contains electrolytes and
bicarbonate in easy-to-mix solutions that reduce pharmancy labor
and the potential for human error
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No additional syringes, lines or sterile water needed
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Enables fast and easy bedside preparation and reduced bag
changes
Includes bar code label to verify that the right formula is
being administered to the right patient
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PrismaSol Replacement Solution
We've done the compounding so you don't have to.
PrismaSol replacement solutions, like PrismaSate® dialysate, is commercially
produced. This feature, when compared with manual compounding and other
solutions that require mixing, assists in the reduction of the complexity and the risk
of error.
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Sterile bag enables fluid to remain stable for 24 hours after the protective
over-wrap is removed and has a 12-month shelf life, ensuring cost-effectiveness
and easy storage
Pre-mixed 5-liter bag reduces bag changes and eliminates the need for
compounding
Fast and easy bedside preparation, read-to-mix within the confines of a 2compartment, 5-liter bag
Provides both options of a spike port and luer lock port for connecting the
replacement fluid line
PrismaSol
Sterile Hemofiltration and Hemodiafiltration solution
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins. This solution is used in Continuous Renal
Replacement Therapies (CRRT) as a replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol is packaged in a two-compartment bag. The small compartment A contains electrolytes and the large
compartment B contains buffer. The final reconstituted solution (5000 mL) is obtained after breaking the red frangible pin
between compartments A and B and mixing both solutions. The compositions of the solution before and after reconstitution
are described in the following tables.
Legal Notice »
© Copyright Gambro Lundia AB, 2007
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PrismaSol Replacement Solution
PrismaSol Replacement Solution
We've done the compounding so you don't have to.
PrismaSol replacement solutions, like PrismaSate® dialysate, is commercially
produced. This feature, when compared with manual compounding and other
solutions that require mixing, assists in the reduction of the complexity and the risk
of error.
•
•
•
•
Sterile bag enables fluid to remain stable for 24 hours after the protective
over-wrap is removed and has a 12-month shelf life, ensuring cost-effectiveness
and easy storage
Pre-mixed 5-liter bag reduces bag changes and eliminates the need for
compounding
Fast and easy bedside preparation, read-to-mix within the confines of a 2compartment, 5-liter bag
Provides both options of a spike port and luer lock port for connecting the
replacement fluid line
PrismaSol
Sterile Hemofiltration and Hemodiafiltration solution
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins. This solution is used in Continuous Renal
Replacement Therapies (CRRT) as a replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol is packaged in a two-compartment bag. The small compartment A contains electrolytes and the large
compartment B contains buffer. The final reconstituted solution (5000 mL) is obtained after breaking the red frangible pin
between compartments A and B and mixing both solutions. The compositions of the solution before and after reconstitution
are described in the following tables.
Legal Notice »
© Copyright Gambro Lundia AB, 2007
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PRODUCTS
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