Thermo Scientific Savant Explorer SpeedVac

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Thermo Scientific Savant Explorer
SpeedVac® Concentrator
Maximizing throughput and
sample integrity in drug
discovery
Part of Thermo Fisher Scientific
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Thermo Scientific Savant Explorer SpeedVac Concentrator
Maximizing throughput and sample integrity in drug discovery
In the drug discovery chain, samples
are precious – and so is time. Every
day you’re under pressure to process
large volumes of samples, working
with speed and precision in pursuit
of new discoveries.
Our Savant Explorer SpeedVac®
concentrator is designed to accelerate
your drug discovery efforts and
remove obstacles to productivity.
This advanced platform protects your
valuable samples and helps you work
more efficiently and productively so
you can spend more time focusing on
new drug development.
The Savant Explorer SpeedVac
concentrator is a technologically
advanced vacuum concentration
system that can stand up to the
heavy demands of a busy, multi-user
laboratory environment. Combining
high-volume sample capacity with an
innovative design and sophisticated
monitoring capabilities, this
concentrator is an ideal highthroughput system for key
pharmaceutical and biotechnology
applications such as drug discovery
compound management, drying of
HPLC fractions, and solid- and
solution-phase synthesis.
A -50°C cold trap is located just inches away from
the chamber, maximizing the speed of solvent
removal and minimizing evaporation times.
The 6-position Snowflake Rotor holds up to:
• (30) shallow-well microplates or
• (12) deep-well microplates or
• (72) 20 ml scintillation vials or
• (90) 16 x 125 mm tubes or
• (144) 1 dram vials or
• (210) 13 x 100 mm tubes
Primary controls – vacuum level, temperature,
heat time, radiant lamp time, run time and vacuum
ramp – are easily set and monitored on the bright,
easy-to-read digital display.
2
The Savant Explorer SpeedVac concentrator
delivers high-throughput in a compact, userfriendly design. It opens like a clam shell,
making it easy to access the chamber to load
and unload your samples.
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High Capacity & Efficient Solvent Evaporation
Increase Your Throughput
Our Savant Explorer SpeedVac
concentrator is a high-capacity
system that can easily accommodate
a large number of samples in a wide
variety of formats. With multiple rotors
and more than twenty blocks to choose
from, the Savant Explorer SpeedVac
concentrator supports sample formats
ranging from tubes, vials and
microplates to large-volume flasks.
Rapid, Efficient Solvent Evaporation
With the Savant Explorer SpeedVac
concentrator, solvent removal is fast
and efficient. The unit’s 5-liter, -55°C
cold trap is positioned just inches
from the chamber. In addition, an
expanded vacuum port and short
More than twenty blocks are available to
support a wide variety of sample formats.
vapor path allow rapid removal of
vapors for improved drying and
effective handling of difficult-toremove solvents like dimethylsulfoxide (DMSO).
The Savant Explorer SpeedVac
concentrator further accelerates the
evaporation rate by maintaining accurate chamber temperatures. This provides the added advantage of reducing vapor condensation in the sample
chamber, which minimizes contamination and cleaning down time.
Dual-format Cold Trap
Another unique and time-saving
feature is the dual-format cold trap.
The two-position high-capacity H-rotor fits eight
aluminum blocks of tubes up to 100 mm in height,
providing a total capacity of up to:
• (96) 20 ml scintillation vials or
• (192) 16 x 100 mm tubes or (192) 1 dram vials or
• (280) 13 x 100 mm tubes
The direct-drain configuration
ensures convenience and safety
by allowing you to drain solvents
directly into a waste container at the
end of the run. The unit’s hot gas
defrost feature and convenient side
drain saves time so you can start the
next run immediately.
For certain acids such as HCl, the trap
can be used with a glass flask inserted
into the trap, allowing the solvent
to collect and freeze directly in the
flask. The flask can be removed for
defrosting, and a clean flask can be
inserted to begin another run.
The two-position Gilson rack rotor fits two
Gilson racks of tubes up to 100 mm in height.
Advanced Controls
Ensure High Sample Integrity
When you are working with small
amounts of fragile samples,
overheating can be a serious concern.
The Savant Explorer Speed Vac
concentrator incorporates numerous
features to eliminate this worry.
Intellitemp Temperature Monitoring
The Savant Explorer SpeedVac
concentrator maintains accurate sample
temperatures through its Intellitemp
monitoring and control system. This
system uses one rotor block probe
and up to three sample probes to
monitor run conditions. When used
with the “Auto-Dry” function, the
Intellitemp system automatically ends
the run when a pre-set temperature is
reached, thereby avoiding overheating.
TM
Anti-bumping design
Pre-programmed vacuum ramps and
pressure controls minimize sample
bumping and cross-contamination
with volatile solvents or mixtures.
In addition, the rotor G-force is
optimized to handle a wide variety
of tubes and protect them against
potentially harmful effects such
as tube breakage.
Two microplate samples:
one evaporated with
vacuum ramping (left),
and one without.
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Advanced Software
Streamlines Your Protocols
The Savant Explorer SpeedVac
concentrator incorporates advanced
software that accelerates your
productivity in the lab:
• Create,
edit and save programs on
your PC or via the console
• Store
and recall pre-set programs
for simple, rapid operation
• Link up
to five programs sequentially
with Timed and Time Plus programs–
ideal for mixed solvent applications
Advanced Linking Software
The Savant Explorer SpeedVac concentrator‘s
advanced software allows you to link up to five
individual programs and run them sequentially.
Simply select the program files in the order that
you want them to run, and link them from the main
menu. Then select “Save linked file” and the
linked program is ready to run.
Optional Software Suite
Provides Complete
Data Logging
Graphing Capability
The optional Software Suite incorporates
a graphing capability that allows you to optimize
your drying process.
The optional Software Suite
provides a comprehensive data
logging capability and numerous
other convenience features:
• Perform
advanced real-time data
logging and graphing from your PC
and transfer data to an Excel
spreadsheet – ideal for GLP, QA and
QC documentation
• Optimize
drying times
• Instantly
Remote Operation
The Savant Explorer SpeedVac concentrator can
be operated remotely from a PC or laptop through
the RS232 port of the instrument. A virtual control
panel in the Software Suite provides access to all
of the concentrator’s control functions. All run
conditions can be captured, displayed, graphed
and saved under a user-defined file name.
4
view a summary of all
programs, methods and parameters
for all links
• Control
all concentrator functions
remotely from your PC
• Open
power-operated lid remotely
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Designed for Maximum Throughput,
Ease of Use and Durability
Compact, Integrated System – With
lab space often at a premium, our
concentrator delivers high-capacity in
a compact footprint. Concentrator,
cold trap and dry pump are combined
in one simple unit that easily fits on a
bench top, within a standard fume
hood or on a cart.
Chemically Resistant – Designed to
withstand the rigors of aggressive
solvents, our Savant Explorer SpeedVac
concentrator is constructed of
highly chemically resistant materials
such as TEFLON®, Kalrez®, highgrade stainless steel and anodized
aluminum. These materials can
withstand constant use with solvents
such as TFA, HCl, DMSO, DCM, DMF1
and acetonitrile.
Unique Ergonomic Design – The
clam-shell design accommodates
safe and easy access to samples by
exposing the front of the chamber.
There is no need to lean into the
chamber and risk inhaling vapors.
Power-Operated Lid for Convenience
and Safety – The electronic lid provides
“hands-off” opening and closing of the
chamber with the press of a button.
The lid can even be controlled
remotely from your PC through the
concentrator’s RS232 port to allow
full venting of residual vapors from
the chamber prior to handling.
Quick, Easy Side Drain – A convenient,
safe side drain allows you to drain
cold trap contents directly into an
appropriate waste container.
Easy-to-Use, Intuitive Control Panel –
Primary controls (vacuum level,
temperature, heat time, radiant lamp
time, run time and vacuum ramp) are
easily set and monitored on the
bright, easy-to-read digital display.
Oil-Free, Maintenance-Free Vacuum
Pump – The oil-free vacuum pump is
resistant to aggressive solvents and
acids, and is virtually maintenance
free. This eliminates the need to
check oil levels, change and dispose
of contaminated oil, and perform
costly rebuilds, which ensures a long
and economical life.
1
Trifluoroacetic acid (TFA), Hydrochloric Acid (HCl),
Dimethyl Sulfoxide (DMSO), Dichloromethane (DCM),
Dimethyl Formamide (DMF)
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Complete Sample Preparation Solutions
Thermo Scientific Savant
Explorer SpeedVac Concentrator Specifications
Technical Specifications
Physical Properties
Integrated (W x D x H) cm (in)
Concentrator (W x D x H) cm (in)
Cold trap/pump (W x D x H) cm (in)
Additional required ventilation space
Misc. items (boxed) (W x D x H) cm (in)
Weight
Concentrator weight, kg (lbs)
Cold trap weight, kg (lbs)
Pump weight, kg (lbs)
Heating
IR Lamp Controls
Timers Settings (x2), Heat, Run, Lamps
Materials of Construction
Chamber
Connections: Concentrator to cold trap tubing
O-rings
Operational Requirements
Voltage input/frequency/power
Rotor spin speed
Imbalance
Vacuum Pump
Capacity
Vacuum Control
Ramp rate
Ultimate vacuum level
Ultimate Vacuum Setting
Display Reading
Cold trap
Capacity
Operating temperature
Refrigerant
Performance Properties
Temperature range
Pre-heat temperature
Modes of operation
Noise
Chemical Compatibility
6
Dimensions (uncrated)
90.2 x 65.1 x 63.5 (35.5 x 25.6 x 25.0)
63.5 x 65.0 x 48.3 (25.0 x 25.6 x 19.0)
62.2 x 64.1 x 43.2 (24.5 x 25.5 x 17.0)
10.2 cm (4 in) on each side
Shipping Dimensions (crated)
–
84 x 66 x 79 (33 x 36 x 31)
84 x 66 x 71 (33 x 36 x 28)
N/A
48 x 48 x 48 (19 x 19 x 19)
Shipping Weight (crated)
127 (279)
139 (306)
7 (15)
Weight (uncrated)
57.1 (126)
57.6 (127)
23.1 (51)
4 IR lamps
On/off/timed
1 min to 9 hrs and 59 mins in 1 min increments, continuous
TEFLON coated aluminum
PTFE
PTFE/EPDM
Explorer-220: 220VAC/60Hz, single phase/20 amps
Explorer-230: 230VAC/50Hz, single phase/20 amps
Explorer-220: 1000 ± 100 rpm (empty rotor)
Explorer-230: 800 ± 100 rpm (empty rotor)
85 grams
ETFE oil-free diaphragm pump
36 L/min @ 60 Hz
32 L/min @ 50 Hz
1 – 4, off
20.0 to 0.1 torr
200 - 0.7 Torr, 26664.5 - 93.33 Pa, 266.65 - 0.933 mbar
Atm – 500 µTorr, 66661.2 Pa, 666.61 mbar
Condenser: 5.5 L
Glass flask: 4.0 L
-50°C
220V - 403B
230V - 404A
Adjustable 35 to 85°C
45°C
Auto-dry: Intellitemp monitoring stops run when sample target temperature profile is reached
Time mode: User defined run time, temperature and vacuum
Time + mode: Customer sets maximum allowable temperature
<63 dBA
Dimethyl sulfoxide (DMSO), dichloromethane (DCM), dimethyl formamide (DMF),
trifluoroacetic acid (TFA), hydrochloric acid (HCl), acetonitrile and other aggressive solvents.
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Technical Specifications
Plug Configuration
220 VAC
230 VAC
Power inlet receptacle
NEMA 6-20 with an IEC 60320 C19 connector
CEE 7/7 with an IEC 60320 C19 connector
IEC 60320 C20
User Interface
Display
Certification (Explorer-230)
Name, store, link, edit, recall
Real-time LED display of parameters
CE
Immunity – EN50082-1
Emissions – EN50081-1
Radio disturbance (ISM) – EN55011
Radio disturbance (Information technology equipment) – EN55011
CAN/CSA
Safety – CAN/CSA-C22.2 No 1010.1-92
Interface/Software
Individual programs
Linked programs
Preset programs
Program linking capability
Embedded
99 individual programs
Varies with number of links used per program
3 – can be edited
Up to 5 individual programs
Create links with timed and time plus programs
No data collection ability
Data logging
Real time alarms
Communication requirements
Applications
Software Suite (optional)
Unlimited
Unlimited
3 – can be edited
Up to 5 individual programs
Same as embedded
Real time data logging
Graphs evaporation rate for each probe
Data transfer to an excel spreadsheet
Indicates run aborted
RS232
Used in drug discovery, combinatorial chemistry, medicinal chemistry, oligonucleotide manufacture,
and natural products.
The First Name in Vacuum Concentration
For more than forty-five years, our Savant SpeedVac® name has been recognized by
scientific researchers and laboratory personnel around the world for delivering value,
reliability, and performance in centrifugal vacuum concentration. We continue to partner
with customers to develop innovative, cost-effective vacuum concentration solutions to
support your scientific challenges.
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Complete Sample Preparation Solutions
Thermo Scientific Savant
Explorer SpeedVac Concentrator
Ordering Information
Ordering Information
Savant Explorer SpeedVac Concentrator
EXPLORER-220
Savant Explorer SpeedVac System.1 Includes one GCF4-EXP glass flask and installation kit, 220vac 60Hz.
EXPLORER-230
Savant Explorer SpeedVac System.1 Includes one GCF4-EXP glass flask and installation kit, 230vac 50Hz.
Rotors
ESR6
6-position Snowflake Rotor. Includes 5 carriers and 1 block probe carrier. Fits tubes up to 150 mm.
EXP-H100
Gilson Rack Rotor. Includes 2 carriers and 1 block probe carrier.
EXP-H200
High Capacity H-Rotor. 8 block capacity. Fits up to 100 mm tube height.
Aluminum Rotor Blocks Cat. no.
Description
No. of Tubes – ESR6
No. of Tubes – EXP-H200
Microcentrifuge Tubes
RBA30-8-30
0.5 mL (8 x 30 mm)
180
240
RBA25-11-39
1.5 mL (11 x 39 mm)
150
200
Glass and Plastic Tubes RBA35-13-100
13 x 100 mm
210
280
RBA24-16-100
16 x 100 mm
144
192
RBA15-16-125
16 x 125 mm
90
RBA24-17-60
17 x 60 mm
144
192
RBA18-20-38
20 x 38 mm
108
144
RBA18-22-40
22 x 40 mm
108
144
RBA12-22-120
22 x 120 mm
72
RBA8-25-150
25 x 150 mm
48
RBA12-28-95
28 x 95 mm
72
96
Centrifuge Tubes
RBA6-30-115
50 mL conical (30 x 115 mm)
36
RBA24-16-100
15 ml conical (17 x 120 mm)
144
Vials
RBA54-12-32
12 x 32 mm
324
432
RBA24-15-45
1 dram vials, 15 x 45 mm
144
192
RBA12-25-52
2 dram vials, 25 x 52 mm
72
96
RBA12-27-60
5 dram vials, 27 x 60 mm
72
96
RBA24-15-75
15 mm vial, 15 x 75 mm
144
192
RBA12-28-58
20 mL scintillation vials, 28 x 58 mm
72
96
Flasks
RBA2-FLSK-100
100 mL round or flat bottom
12
RBA1-FLSK-250
250 mL round or flat bottom
6
RBA1-FLSK-500
500 mL round or flat bottom
6
Beakers
RBA24-17-31
3 mL beakers (17 x 31 mm)
144
192
Microplates
UPC2-EXP
Deepwell, shallow well (double shelf carrier)
12
UPC5-EXP
Shallow well (5-shelf carrier)
30
UPC5-EXP-HTSP
Universal plate carrier for shallow well plates with heat sink base plate
Heat Sink Plates
HTSP-96V
V bottom, 96-well microplate
HTSP-96R
Round bottom, 96-well microplate
HTSP-24R
Round bottom, 24-well microplate
Accessories
EXP-SOFT
Software Suite for data logging
DC120A2
Disposable cartridge for neutralizing acid
EXP-SOFT-PACK
Software Suite and PC
DC120R
Disposable cartridge for trapping volatile radioactivity
GCF4-EXP
Glass flask
DTK120R
Chemical trap kit includes SCT120, DC120R and tubing
PROBE-EXP
Temperature probes
ANT100
Post-trap assembly (NSA300TF acid neutralizing and ANS
PTFE-SLV
PTFE probe covers
121/4 ammonia neutralizing solutions ordered separately)
CC120/EXP
Cart
ANS121
Ammonia neutralizing solution
SCT120
Chemical trap (order cartridges separately)
NSA300TF
Neutralizing solution for acid
SCC12
CryoCool® heat transfer fluid (1 liter)
1
Rotors, carriers, probes & CryoCool not included. 2 Hazardous materials require special shipping and handling.
© 2007 Thermo Fisher Scientific Inc. All rights reserved. Teflon® is a trademark of E. I. du Pont de Nemours and Company. Kalrez® is a trademark of DuPont Dow Elastomers. All other trademarks are the property of Thermo Fisher
Scientific Inc. and its subsidiaries. Specifications, terms and pricing are subject to change. Not all products are available in all countries. Please consult your local sales representative for details.
North America: +1 866 984 3766
Europe: Austria +43 1 801 40 0, Belgium +32 2 482 30 30, Finland +358 9 329 100, France +33 2 28 03 20 00,
Germany: national toll free 08001-536 376, international +49 6184 90 6940, Italy +39 02 95059 1, Netherlands +31 76 571 4440,
Russia/CIS +7 095 225 11 15, Spain/Portugal +34 93 223 3154, Switzerland +41 44 454 12 12, UK/Ireland +44 870 609 9203
Asia: India +91 22 5542 9494, Japan +81 45 453 9220, China +86 21 6865 4588 or +86 10 5850 3588,
Other Asian countries +852 2885 4613
Countries not listed: +49 6184 90 6940 or +33 2 28 03 20 00
www.thermo.com/explorer
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