Board Members

 Welcome to the International Photodynamic Association (IPA). The IPA was founded in 1986 and its
membership consists of prominent clinicians, scientists and others worldwide, who are involved in
performing, researching or promoting photodynamic therapy (PDT) and photodiagnosis (PD) and
related technologies. The purpose of the IPA is to promote the study of diagnosis and treatment using
light and photosensitisers, to disseminate such information to its members, the medical community and
to general public.
The IPA organises an International Congress every two years, which is a unique opportunity to sum up
research activities in the clinical and basic research aspects of PDT/PD. We hope that you will find it a
useful resource for your PDT and PD activities.
Secretary General of the IPA 2013
Board Members
Ahn, Woong Shick
Department Of Obstetrics & Gynecology Kangnam St. Mary's
Hospital,
College Of Medicine, The Catholic University Of Korea,
505 Banpo-dong, Seocho-ku,
Seoul
Korea
Email: [email protected]
Allison, Ron (M.D.)
Professor & Chairman, Radiation Oncology East Carolina
University School Of Medicine Radiaton Oncology
Department Leo Jenkins Cancer Centre
600 Moye Boulevard
Greenville
Usa
NC 27834
Email: [email protected]
Bagnato, S. Vanderlei
Ifsc/university Of Sao Paulo
Av. Trabalharo Sao Carlence,
400 Sao Carlos - Sp 13566-590
Brazil
Email: [email protected]
Education:
PhD from MIT (1987).
Double major in Material Science Engineering (Universidade Federal de São Carlos - Brasil - 1981)
and Physics (Universidade de São Paulo - Brasil - 1981).
Received the title of "Livre - Docente"t by University of São Paulo (1989) and Full Professor by
University of São Paulo (1993).
Biography:
BRIEF HISTORY
Has his activities based on laser cooling and trapping of neutral atoms and applications of optics and
laser in dentistry and medicine.
Among many activities, he pursued a pioneering work in the field of atomic and molecular physics
with worldwide recognition.
Recently the laboratory under his guidance laboratory has achieved Bose-Einstein Condensation
initiating a pioneering work with quantum macroscopic matter. Include in the diversity of activities, is
the responsibility for the construction and evaluation of the first atomic clock developed in Latin
America and the first pilot plant for the production of high precision microscopes.
Recently the group of research under his guidance has implemented in Brazil, for the first time, the
clinical use of Photo-Dynamic-Therapy for the treatment of cancer.
A strong relation between basic research and industry is one of the characteristics of the work carried
on by Bagnato, resulting in the implementation of high technology industries in the field of optics.
He has had published over 240 papers in international journals, with more than 2000 citations.
During his academic life, he has supervised more than 45 graduate students and he is presently
supervising 17 graduate students involved in several programs of research as well as many
undergraduates.
He maintains close international relations with many institutions around the world.
He has been the editor of the Brazilian Teaching Journal and belongs to the editorial board of several
international journals.
Barron, J. Patrick
Email: [email protected]
Biography:
Born in Scotland, he graduated from the University of Pennsylvania and
went to study Japanese in Japan in 1969. His graduate studies consisted of
the history of ancient Japanese and the history of Kyogen, medieval
Japanese comic drama.
He began his career in medical writing in 1970 under the aegis of Dr.
Yoshihiro Hayata of Tokyo Medical University (TMU), past president of the
International Association for the Study of Lung Cancer, Japan Respiratory Society and the Japan
Surgical Society. Patrick pioneered the field of English for medical purposes in Japan, and is on the
editorial board of many journals, including CHEST, the Journal of Bronchology and Respirology. He
has translated from Japanese or edited about 15 medical textbooks, several of which have won awards.
In 1978, he was by Dr. Yoshihiro Hayata to Buffalo, together with Harubumi Kato and Masayuki
Nitsuma to see what was being achieved by Dr. Tom Dougherty and whether photoradiation therapy,
PRT, as PDT was known in those days, could be evaluated using the experimental model of lung
cancer in dogs that had been developed by Professor Hayata and his staff at Tokyo Medical University.
From then on, Patrick had the opportunity to take part in about all the meetings concerning PDT that
were held, mainly in North America, but also in Japan, and in 1984 proposed to Dr. Hayata that it was
time to hold a meeting on the clinical applications of PDT. The first conference on what was to become
the IPA was held in 1986 in Tokyo. Since the society did not exist, the conference had the rather
clumsy name of the First International Conference on the Clinical Applications of Photodynamic
Therapy, and at the meeting, Patrick suggested that the chairs of major sessions meet and discuss
whether it was necessary to have a society devoted the subject. It was decided that there was a
necessity, and the name of the society was proposed by Dr. Denis Cortese of the Mayo Clinic. The
name he proposed was, as it is today, the International Photodynamic Association.
In 1991, he established the first Asian medical communications center devoted to improving the flow
of medical information from Japan to the International medical community, at TMU, providing support
to staff submitting and resubmitting papers. Publications from TMU have increased 700% in the past
20 years. As Vice Chairman of the Japan Society for Medical English Education, he provided the initial
impetus for the first medical testing of English competence for medical professionals in Japan, which
began in 2007.
Berg, Kristian (PhD)
Dept. Of Radiation Biology, Norwegian Radium Hospital
Rikshospitalet
Montebello
N-0310 Oslo
Norway
Email: [email protected]
Education:
Cand.real (MSc) in biochemistry, University of Oslo, 1985
Dr.philos (PhD) in experimental PDT, University of Oslo, 1990
Position:
Senior scientist, Head of PCI group, Dept. of Radiation Biology, Radiumhospitalet-Rikshospitalet
Medical Center.
Awards:
- 1st price from the University of Oslo and the Oslo Research Park for scientific projects with
commercial potential 1995;
- The Norwegian Radium Hospitals research awards for 1999 and 2002;
- Claude Rimingtons memorial award for 2000;
- Pater-Leander-Fischer prize by Deutsche Gesellschaft für Lasermedizin for 2007.
Biography:
Research fields:
Photodynamic therapy (PDT), mechanisms involved in the treatment effects of PDT in vitro and in
vivo.
Photochemical internalization (PCI)., a method for photochemical delivery macromolecular
therapeutics, under development for use in e.g. gene therapy (utilization of non-viral and adenoviral
vectors for transfection/transduction of cells and peptide nucleic acids (PNA) for inhibition of gene
expression in vitro), protein toxin therapy and chemotherapy.
Some relevant appointments:
- President of European Society for Photobiology (ESP) for the period 2007-2009
- President-Elect of European Society for Photobiology (ESP) for the period 2005-2007
-Officer in the Executive Committee of the European Society for Photobiology (ESP) for the period
1999-2005,
- Chairman of the Education and Training Committee in ESP for the period 2005-2007 and member of
this committee for the period 2001-2005.
- Member of Organizing Committee for the 9th -12th Congress's of European Society for
Photobiology, the 1st joint SBS-ESP workshop on Biophotonics, Bratislava, Sept10-12,2006, and
"Conference on photosensitization and photochemotherapy of cancer", 16-17.mars 1993 in Oslo.
- Associated Editor of Photochemical & Photobiological Sciences, 2008- Member of the Ownership Board of the journal Photochemical & Photobiological Sciences, 20072009.
- Member of the Steering Committee of the European Platform for Photodynamic Medicine (EPPM).
- Member of Scientific Programme Committee of European Society for Photobiology Congresses in
1999-2007,
-Member of Scientific Programme Committee for IPA (International Photodynamic Association)
congress (Munich) in 2005 and in 2007 (Shanghai).
- Member of Scientific Programme Committee for the 1st joint SBS_ESP workshop on Biophotonics,
Bratislava, Sept 10-12, 2006
- Member of the Advisory Board for the journal "Photodiagnosis and Photodynamic Therapy"
(Elsevier)
- Guest associated editor for the journal "Photochem.Photobiol.Sci", Dec 2007 issue
Biel, Merrill A. (MD PhD)
Advanced Photodynamic Technologies, Inc
2715 4th Street, Se Suite 70
Minneapolis
Usa
MN 55414
Email: [email protected]
Biography:
Dr. Merrill Biel is an Otolaryngologist - Head and Neck Surgical Oncologist at Ear, Nose and Throat
SpecialtyCare of Minnesota and Medical Director of Head and Neck Oncology at the Virginia Piper
Cancer Institute at Abbott-Northwestern Hospital in Minneapolis.
He is an associate clinical professor in the departments of surgery, otolaryngology and family practice
and a clinical professor in the School of Veterinary Medicine at the University of Minnesota.
Dr. Biel has been involved in the preclinical and clinical applications of photodynamic therapy in head
and neck cancer since 1987. He has been the principal investigator on an international multiinstitutional trial of photodynamic therapy in the treatment of head and neck cancer and has treated
over 400 patients with head and neck cancer using PDT, the largest single series of PDT treatment for
head and neck cancer in the world.
He is considered one of the world's leading experts in the clinical use of photodynamic therapy for
cancer treatment and is actively involved in the preclinical and clinical evaluation of new
photosensitizers for the treatment of head and neck cancers. His PDT research also involves
applications of PDT for the treatment of microbial biofilms.
Dr. Biel has published over 30 manuscripts and 4 book chapters on pre-clinical and clinical
applications of photodynamic therapy using various photosensitizers and laser systems.
He has been a course director and guest faculty at numerous PDT training programs for physicians.
Cross, Carolyn
Ms. Cross was one of the initial founders and financial
supporters of Ondine Biomedical Inc., and currently serves
as the Chairman of the Board and Chief Executive Officer
of the company. With more than 20 years of experience
working with early stage companies and 28 years of
experience with public market securities, she was
previously responsible for managing various funds as a
Vice President with Royal Bank Investment Management
Inc., the fund management arm of the Royal Bank of
Canada. Ms. Cross currently sits on a number of boards,
including Periowave Dental Technologies, Inc., OrGenX Biopharma Corp., and
Sinuwave Technologies Corporation. She also serves on the Advisory Board of the
McGill University Dental School and is a Board member and Treasurer for the
International Photodynamic Association. Ms. Cross was appointed by the Minister of
Industry to the Board of The Canada Foundation for Innovation (CFI), an independent
corporation created by the Government of Canada to fund research infrastructure
within Canada and is a Jubilee Award Recipient from the Government of Canada. Ms.
Cross holds a CFA designation, an MBA from York University and an Honours in
Business Administration from Western University.
Other memberships:
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CFA Institute and CFA society
Courthill Foundation
Toronto Society of Financial Analysts
Toronto Financial Services Alliance (TFSA)
Association for Professionals in Infection Control and Epidemiology (APIC)
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Community and Hospital Infection Control Association – Canada (CHICA)
The Executive Committee (TEC)
Women Presidents’ Organization (WPO)
International Women’s Forum (IWF)
Professional Woman's Network (PWN)
Founder, Women’s Economic Business Advisory Council (WE BAC Women)
Ernst & Young Global Women In Business Advisory Council
UnitedSucces
Society for Canadian Women in Science & Technology
Curnow, Alison(Ph.D)
Cornwall Dermatology Research
Peninsula Medical School
Knowledge Spa
Royal Cornwall Hospital
Truro
Cornwall
Uk
TR1 3HD
Telephone:
Fax:
Email: [email protected]
Education:
Certificate in Clinical Research, University of Leeds (Sept 2001 - Aug 2002).
Postgraduate Certificate in Education (Adult), University of Plymouth (Oct 2000-Sept 2002).
PhD Surgery (Clinical Studies), University College London (Sept 1994 - Aug 1999);
entitled "Photodynamic therapy with aminolaevulinic acid (ALA) - Techniques for enhancement". BSc
(Hons) Medical Biochemistry, University of Surrey (Oct 1990 - Jun 1994).
Position:
- Senior Lecturer in Cell and Molecular Biology, Peninsula Medical School(Apr 2003 - to present).
- Medical Research Director, Cornwall Dermatology Research, Royal Cornwall Hospital (Apr 2003 to present).
- Editor of the Journal of Photochemistry and Photobiology B: Biology (Dec 2001 - to present).
- Director of the International Photodynamic Association Board (Jun 2005 - to present).
- Post-Doctoral Research Fellow and Project Manager, Cornwall Dermatology Research Project, Royal
Cornwall Hospital (Sept 1999 - Apr 2003).
- Research Fellow, National Medical Laser Centre, University College London Medical School (Sept
1994 - Aug 1999) (whilst completing a PhD part-time).
- Research Assistant, Department of Clinical Oncology, Imperial Cancer Research Fund, Guy's
Hospital, London (Sep 1992 - Aug 1993)(as a Professional Training Year).
Biography:
Research Interests:
Cornwall Dermatology Research is currently conducting experimental laboratory research and clinical
investigations of photodynamic therapy (PDT) in parallel. This research is mainly focussing on
enhancing PDT (particularly with iron chelating agents) in order to treat thicker skin cancers in a more
effective way than currently possible. This is important locally, as Cornwall has the highest levels of
skin cancer in the UK. In addition to PDT treatment our laboratory is also investigating skin cancer
causation and prevention. The level of DNA damage produced in cultured human cells by ultraviolet
light in the presence of various different modulating chemicals (particularly naturally occurring
antioxidants) is assessed using single cell gel electrophoresis (the comet assay).
Eljamel, M Sam (MBBCh, MD, FRCSIr, FRCSEd, FRCS(SN), ACS-ALB
Prof Eljamel graduated with honours in 1982, fellow of the Royal
Colleges of Surgeons of Edinburgh and in Ireland and the Royal society
of Medicine. Prof sub-specialist interests are in Stereotactic/ Functional
Neurosurgery and neuro-oncology/PDT. He provides secondary and
tertiary services for the region and has patients referred from other
regions in Scotland and the UK. His current research encompasses the
application of technology, robotics and photodynamic techniques in
neurosurgery. He thought on AANS workshop surgical treatment of PD
for 3 years, organized MRI guided DBS hands on workshop in Dundee
for two years. He was honorary secretary for the BSSFN for 4 years and
current honorary secretary of Committee on Neurosurgery of
Psychiatric Disorders (CNPD) of the WSSFN. He had over 90
publications, more than 200 presentations and invited lectures, written
20 book chapters and edited three books (M S Eljamel on PubMed ). He
is an associate Editor of four journals and reviewer to 20 scientific
journals. He served a board member of tumor section of AANS/CNS (USA), SANON (Scotland), and
the IPA (International). He is a trustee of UKPDT, and Medical Laser research (Tayside), Clinical
director Scottish PDT centre, intercollegiate examiner in Neurosurgery, examiner in neuroophthalmology (RCSE) and chaired clinical governance committee, and Tayside malignant cord
compression group and current Chairman of Mede Lase Charity. He was elected Secretary General of
the IPA in 2013.
Furukawa, Kinya
Department Of Thoracic Surgery,
Medical University Hospital, Kasumigaura Hospital 3-20-1
Chuo, Ami-machi, Inashiki-gun, Ibaraki 300-0395,
Tokyo
Japan
Telephone: +81-29-887-1161
Fax: +81-29-887-1266
Email: [email protected]
Education:
1985 Graduated from Tokyo Medical University. Passed the
Licensing Examination of the National Medical Board (M.D.).
1985-1988 Residency training in the Department of Thoracic
Surgery at Tokyo Medical University.
1989 Ph., D. in Surgery, Tokyo Medical University.
1989-1991 Medical staff of the Department of Thoracic Surgery, Tokyo Medical University.
1992- Lecturer, Department of Thoracic Surgery, Tokyo Medical University
2001 Assistant Professor, Department of Thoracic Surgery, Tokyo Medical University, Kasumigaura
Hospital
2004 Associate Professor, Department of Thoracic Surgery, Tokyo Medical University, Kasumigaura
Hospital
2007 Professor, Department of Thoracic Surgery, Tokyo Medical University, Kasumigaura Hospital
Position:
As Professor in Thoracic Surgery, activities include clinical work as a surgeon, teaching junior staff
and performing own research of photodynamic diagnosis and therapy for lung cancer.
Hahn, M. Stephen
Hospital Of The University Of Pennsylvania
Radiation Oncology Department 3400 Spruce Street - 2 Donner
Philadelphia
Usa
PA 19104
Email: [email protected]
Education:
Rice University B.A. 1980
Biology Temple University School of Medicine M.D. 1984
Medicine
Position:
Henry K. Pancoast Professor and Chair
Awards:
1984-1985 Julius R. Krevans Prize for Clinical Excellence, University of California San Francisco
1984 Joseph C. Doane Memorial Prize "For the highest average covering four years of medical school"
Temple University School of Medicine
1984 Thomas W. Durant Prize in internal medicine, Temple University School of Medicine.
1999 Giulio J. D'Angio, M.D, Award for Excellence in Teaching in Radiation Oncology
Biography:
Postgraduate Training
1984-1987 University of California, San Francisco Hospitals, Department of Internal Medicine San
Francisco, California Internship and Residency
1987-1988 University of California, San Francisco Hospitals, Department of Internal Medicine, Chief
Resident
1988-1991 National Cancer Institute, Medicine Branch, Fellowship, Medical Oncology
1991-1994 National Cancer Institute, Radiation Oncology Branch, Residency Experience
1987-1988 Chief Resident, Department of Medicine, University of California, San Francisco, CA.
1993-1995 Attending Physician, Medicine Branch, National Cancer Institute, Bethesda, MD
1994-1995 Chief, Prostate Cancer Clinic, Clinical Pharmacology Branch, National Cancer Institute,
Bethesda, MD.
1995 Community Attending Physician, Family Practice Residency Community Hospital Santa Rosa,
CA
1995-1996 Medical and Radiation Oncologist Redwood Regional Oncology Santa Rosa, CA
1996-2001 Assistant Professor, Radiation Oncology, Division of Hematology-Oncology, University of
Pennsylvania, Philadelphia, PA
2001 -2005 Associate Professor, Radiation Oncology, Division of Hematology-Oncology, University
of Pennsylvania, Philadelphia, PA
2005- Professor and Chairman, Radiation Oncology, University of Pennsylvania, Philadelphia, PA
PROFESSIONAL SOCIETY MEMBERSHIPS AND SERVICE 1983 Alpha Omega Alpha
1992 American Society of Clinical Oncology
1995 American Society of Therapeutic Radiology
1998 American Society of Photobiology
1999 American Association of Cancer Research
PUBLICATIONS: (List in chronological order; if a partial list is given, indicate total number of
publications)
1. Hahn SM, Tochner Z, Krishna CM, Glass J, Wilson L, Samuni A, Sprague M, Venzon D, Glatstein
E, Mitchell JB and Russo A. Tempol, a stable free radical, is a novel murine radiation protector. Cancer
Res 52:1750-1753, 1992.
2. Hahn SM, Wilson L, Krishna CM, Liebmann J, DeGraff W, Gamson J, Samuni A, Venzon D and
Mitchell JB. Identification of nitroxide radioprotectors. Rad Res 132:87-93, 1992.
3. Hahn SM, Krishna CM, Samuni A, DeGraff W, Cuscela DO, Johnstone P and Mitchell JB. Potential
use of nitroxides in radiation oncology. Cancer Res 54:2006S, 1994.
4. Hahn SM, Sullivan, FJ, DeLuca AM, Krishna CM, Wersto N, Venzon D, Russo A, Mitchell JB.
Evaluation of Tempol Radioprotection in a Murine Tumor Model Free Radic Biol Med 22:1211-1216,
1996.
5. Evans SM, Hahn SM, Pook DR, Jenkins WT, Chalian AA, Zhang P, Stevens C, McKenna WG, Lord
EM and Koch CJ. Detection of Hypoxia in Human Squamous Cell Carcinoma by EF5 Binding. Cancer
Res 60:2018-2024, 2000.
6. Zhu TC, Hahn SM, Kapatkin AS, Dimofte A, Rodriguez CE, Vulcan TG, Glatstein E, and Hsi RA,
In vivo Optical Properties of Normal Canine Prostate at 732 nm Using motexafin lutetium-mediated
photodynamic therapy. Photochem. Photobiol. 77:81-88, 2003.
7. Freidberg, J.S., Mick, R., Stevenson, J., Metz, J., Zhu, T., Buyske, J., Sterman, D., Pass, H.,
Glatstein, E., and Hahn, S.M. A Phase I Study of Foscan-mediated Photodynamic Therapy and Surgery
in patients with mesothelioma. Ann Thorac Surg. 75:952-959, 2003.
8. Colevas, A.D., Brown, J.M., Hahn, S., Mitchell, J., Camphausen, K., Coleman, C.N. for the National
Cancer Institute Radiation Modifier Working Group. Development of Investigational Radiation
Modifiers. J Natl Cancer Inst 95(9): 646-651, 2003.
9. Yom, S.S., Busch, T.M., Friedberg, J.S., Wileyto, E.P., Smith, D., Glatstein, E., and Hahn, S.M.
Elevated serum cytokine levels in mesothelioma patients treated with pleurectomy or extrapleural
pneumonectomy and adjuvant intraoperative photodynamic therapy. Photochem Photobiol 78:75-81,
2003.
10. Brunner, T.B., Hahn, S.M., Gupta, A.K., Muschel, R.J., McKenna, W.G., and Bernhard, E.J.
Farnesyltransferase inhibitors: An overview of the results of pre-clinical and clinical investigations.
Cancer Res 79:569-576, 2003.
11. Friedberg, J.S., Mick, R., Stevenson, J.P., Zhu, T., Busch, T.M., Shin, D., Smith, D., Culligan, M.,
Dimofte, A., Glatstein, E., and Hahn, S.M. A Phase II Trial of Pleural Photodynamic Therapy (PDT) in
patients with Non-small cell Lung Cancer (NSCLC) with Pleural Spread. J Clin Onc, 22:2192-2201,
2004.
12. Busch, T.M., Hahn, S.M., Wileyto, E.P., Koch, C.J., Fraker, D.L., Zhang, P., Putt, M., Gleason, K.,
Shin, D.B., Emanuele, M.J., Jenkins, K., Glatstein, E., and Evans, S.M. Hypoxia and Photofrin Uptake
in the Intraperitoneal Carcinomatosis and Sarcomatosis of Photodynamic therapy Patients. Clin Cancer
Res 10:4630-4638, 2004.
13. Evans, S.M., Judy, K.D., Dunphy, I., Jenkins, W.T., Nelson, P.T., Collins, R., Wileyto, E.P.,
Jenkins, K., Hahn, S.M., Stevens, C.W., Judkins, A.R., Phillips, P., Geoerger, B., Koch, C.J.
Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5
binding. Cancer Res 64:1886-1892, 2004.
14. Evans, S.M., Judy, K.D., Dunphy, I., Jenkins, W.T., Hwang, W.T., Nelson, P.T., Lustig, R.A.,
Jenkins, K., Magarelli, D.P., Hahn, S.M., Collins, R.A., Grady, M.S., Koch, C.J. Hypoxia is important
in the biology and aggression of human glial brain tumors. Clin Cancer Res Dec 15;10(24):8177-84,
2004.
15. Martin, N.E., Brunner, T.B., Kiel, K.D., DeLaney, T.F., Regine, W.F., Mohiuddin, M., Rosato,
E.F., Haller, D.G., Stevenson, J.P., Smith, D.,, Pramanik, B., Tepper, J., Tanaka, W.K., Morrison, B.,
Deutsch, P., Gupta, A.K., Muschel, R.J., McKenna, W.G., Bernhard, E.J., and Hahn, S.M. A Phase I
Trial of the Dual Farnesyltransferase and Geranylgeranyltransferase Inhibitor L-778,123 and
Radiotherapy for Locally Advanced Pancreatic Cancer. Clin Cancer Res 10:5447-5454, 2004.
16. Gupta, A.K., Soto, D.E., Feldman, M.D., Goldsmith, J.D., Mick, R., Hahn, S.M., Machtay, M.,
Muschel, R.J., and McKenna, W.G. Signaling pathways in NSCLC as a Predictor of Outcome and
Response to Therapy. Lung 182(3):151-62, 2004
17. Metz, J.M., Smith, D., Mick, R., Lustig, R., Mitchell, J., Cherakuri, M., Glatstein, E., and Hahn,
S.M. A Phase I Study of Topical Tempol for Prevention of Alopecia Induced by Whole Brain
Radiotherapy. Clin Cancer Res 10:6411-6417, 2004.
18. Wang, H-W., Zhu, T. C., Putt, M.E., Solonenko, M., Metz, J., Dimofte, A., Miles, J., Fraker, D.L,
Glatstein, E., Hahn, S.M., and Yodh, A.G. Broadband reflectance measurements of light penetration,
blood oxygenation, hemoglobin concentration, and drug concentration in human intraperitoneal tumors
before and after photodynamic therapy. J Biomed Optics Jan-Feb;10(1):14004, 2005,
19. Zhu, T.C., Finlay, J.C., and Hahn, S.M. Determination of the distribution of light, optical
properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin
lutetium-mediated photodynamic therapy. J. Photochem Photobiol B. Jun1;79(3):231-41, 2005
20. Zhu, T.C, Dimofte, A., Finlay, J.C., Stripp, D., Busch, T., Miles, J., Whittington, R., Malkowicz,
S.B., Tochner, A., Glatstein, E., and Hahn, S.M. Optical Properties of Human Prostate at 732 nm
Measured In Vivo during Motexafin Lutetium-Mediated Photodynamic Therapy. Photochem Photobiol
Jan-Feb. 81(1):96-105, 2005.
21. Altschuler, M.D., Zhu, T.C., Li, J., Hahn, S.M. Optimized interstitial PDT prostate treatment
planning with the Cimmino feasibility algorithm. Med Phys Dec;32(12):3524-36, 2005.
22. Hahn, J.S., Hahn, S.M., Kammann, H., Barkovich, A.J., Clegg, N.J., Delgado, M.R., Levey, E.
Endocrine disorders associated with holoprosencephaly. J Pediatr Endocrinol Metab Oct;18(10):93541, 2005.
23. Cengel, K.A., Hahn, S.M., Glatstein, E. C225 and PDT combination therapy for ovarian cancer: the
play's the thing. J Natl Cancer Inst Oc 19;97(20):1488-9, 2005.
24. Brunner, T.B., Cengel, K.A., Hahn, S.M., Wu, J., Fraker, D.L., McKenna, W.G., Bernhard, E.J.
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras. Cancer Res
Sep 15;65(18):8433-41, 2005.
25. Busch, T.M., Hahn, S.M. Multidrug resistance in photodynamic therapy. Cancer Biol Ther
Feb;4(2):195-6, 2005.
26. Hahn, S.M., Putt, M.E., Metz, J., Shin, D.B., Rickter, E., Menon, C., Smith, D., Glatstein, E.,
Fraker, D.L., Busch, T.M. Photofrin uptake in the tumor and normal tissues of patients receiving
intraperitoneal photodynamic therapy. Clin Cancer Res Sep 15;12(18):5464-70, 2006.
27. Pore, N., Gupta, A.K., Cerniglia, G.J., Jiang, Z., Bernhard, E.J., Evans, S.M., Koch, C.J., Hahn,
S.M., Maity, A. Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and
increases tumor oxygenation: implications for radiotherapy. Cancer Res Sep 15;66(18):9252-9, 2006.
28. Du, K.L., Mick, R., Busch, T.M., Zhu, T.C., Finlay, J.C., Yu, g., Yodh, A.G., Malkowicz, S.B.,
Smith, D., Whittington, R., Stripp, D., Hahn, S.M. Preliminary results of interstitial motexafin
lutetium-mediated PDT for prostate cancer. Lasers Surg Med Jun;38(5):427-34, 2006.
29. Ross, H.M., Smelstoys, J.A., Davis, G.J., Kapatkin, A.S., Del Piero, F., Reineke, E., Wang, H.,
Zhu, T.C., Busch, T.M., Yodh, A.G., Hahn, S.M. Photodynamic therapy with motexafin lutetium for
rectal cancer: a preclinical model in the dog. J Surg Res Oct;135(2):323-30, 2006.
30. Hahn, S.M., Fraker, D.L., Mick, R., Metz, J., Busch, T.M., Smith, D., Zhu, T., Rodriguez, C.,
Dimofte, A., Spitz, F., Putt, M., Rubin, S.C., Menon, C., Wang, H.W., Shin, D., Yodh, A., Glatstein, E.
A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and
sarcomatosis. Clin Cancer Res Apr 15;12(8):2517-25, 2006.
31. Verigos, K., Stripp, D.C., Mick, R., Zhu, T.C., Whittington, R., Smith, D., Dimofte, A., Finlay, J.,
Busch, T.M., Tochner, Z.A., Malkowicz, S., Glatstein, E., Hahn, S.M. Updated results of a phase I trial
of motexafin lutetium-mediated interstitial photodynamic therapy in patients with locally recurrent
prostate cancer . J Environ Pathol Toxicol Oncol 25(1-2):373-87, 2006.
32. Evans, S.M., Fraker, D., Hahn, S.M., Gleason, K., Jenkins, W.T., Jenkins, K., Hwang, W.T.,
Zhang, P., Mick, R., Koch, C.J. EF5 binding and clinical outcome in human soft tissue sarcomas. Int J
Radiat Oncol Biol Phys Mar 1;64(3):922-7, 2006.
OTHER SUPPORT
Hahn, Stephen M. Active P01 CA87971-05 (E. Glatstein, S. Hahn, Project Leader) 9/7/01-8/31/07 9%
(1.08 Calendar Months) (No salary support during no-cost extension) NIH $965,360 (Direct costs-Yr.
5) Photodynamic Therapy for Intraperitoneal Neoplastic Diseases The goal of this P01 is to study the
three major components of PDT (photosensitizer, oxygen and light) to optimize treatment of patients
with abdominal sarcomas, ovarian and gastrointestinal carcinomas. Dr. Hahn is the Project Director of
Project 2.
R01-CA095160-03 (Hahn, S. P.I.) To be combined with PO1-CA75138 09/30/03 - 08/31/07 10% (1.2
Calendar Months) (No salary support during no-cost extension) NIH $244,749 (direct cost) Clinical
Trials of FTI Radiosensitization Long Term objectives of this project is to develop R115777 in
combination with radiotherapy as a targeted therapy for patients with non-small cell lung cancer
(NSCLC).
5P30 CA16520-31 (Glick) 12/1/99 - 11/30/09 10% (1.20 Calendar Months) NIH $3,898,962 (Direct
Cost) Abramson Cancer Center of the U of P Core Support Grant
5R01-CA109456-02 ( T. Zhu) 06/20/05 - 05/31/09 1% (.12 Calendar Months) NIH $197,500 (direct
cost) Real-Time PDT Dosimetry with Feedback Light Delivery
5P01 CA75138 (Hahn) 8/17/98-5/31/08 10% (1.2 Calendar Months) NIH $1,114,876 Molecular
Targets for Manipulation of Drug and Radiation Sensitivity The goal of this program project is to study
cell cycle checkpoint control in the context of the potential for therapeutic intervention. There are three
sub-themes: 1) a mechanism and signaling of the DNA damage checkpoints, 2) drug and radiation
sensitivity, and 3) apoptosis. The ultimate result of the program project, which comprises four projects
plus three supporting cores, will be a better understanding of how radiotherapy and chemotherapy may
integrate knowledge of cell cycle checkpoints into the development of new treatment strategies. Dr.
Hahn is the overall PI, and Core Leader of the Administrative Core.
Pending 1R01CA127592-01 (Farrar) 04/01/07 - 03/31/11 10% (1.2 months) NIH $307,759 (direct
costs) Acupuncture efficacy for radiation therapy fatigue Association of American Medical Colleges
(AAMC) 10/01/06 - 09/30/08 2% (.24 months) (Barg) $127,077 (direct costs) Understanding post-BCS
treatment choice among low income women with breast cancer R21 CA121580-01 (Gupta) 12/01/06 11/30/08 5% (.6 months) NIH $250,000 (direct costs) Radiosensitization with the HIV protease
inhibitor Nelfinavir in NSCLC The broad goals of this application are to explore the mechanisms by
which nelfinavir results in sensitization and the development of the clinical use of nelfinavir as a
radiation sensitizer. P01 CA87971-06 (E. Glatstein, S. Hahn, Project Leader) 12/01/07-11/30/12 10%
(1.20 Calendar Months) NIH $1,146,589 (Direct costs-Yr. 6) Photodynamic Therapy for
Intraperitoneal Neoplastic Diseases The goal of this P01 is to study the three major components of PDT
(photosensitizer, oxygen and light) to optimize treatment of patients with abdominal sarcomas, ovarian
and gastrointestinal carcinomas. Dr. Hahn is the Project Director of Project 2.
Hasan, Tayyaba (Ph.D.)
Professor Of Dermatology
Harvard-massachusetts Institute Of Technology (mit)
Cambridge
Ma
Usa
Telephone:
Fax:
Email: [email protected]
Position:
Professor of Dermatology, Harvard Medical School Wellman Center
for Photomedicine, Massachusetts General Hospital Boston,
Massachusetts, USA
Director of the Office for Research Career Development, Massachusetts General Hospital, Boston,
Massachusetts, USA
Affiliated Faculty, Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences
and Technology, Cambridge, Massachusetts, USA
Weblink: The Wellman Center for Photomedicine
Biography:
Dr. Tayyaba Hasan has a research program in photobiology and photodynamic therapy and serves on
various committees within Harvard Medical School, including the Subcommittee of Professors, the
Faculty Council of the Medical School, and on MIT-HST's Search Committee, as well as in various
capacities at MGH and the Wellman Center. She is the Program Director for a National Cancer
Institute funded multi-site Program Project Grant with additional research funding from the National
Institutes of Health, the Department of Defense, and industry. In the fall of 2005 she was awarded one
of 12 Cancer Nanotechnology Platform Partnerships designated by the National Cancer Institute for her
project, "Photodestruction of Ovarian Cancer: ErbB3 Targeted Aptamer-Nanoparticle Conjugate." She
serves on a number of national and international grant review committees, including the National
Institutes of Health and the Department of Defense study sections.
Hopper, Colin
Tel: 020 3447 2159
Fax: 020 3447 2152
Email: [email protected]
Location:
University College Hospital
Specialities:
Head and neck, Photodynamic therapy and cancer (PDT), Head
and neck centre
Professional background Mr Hopper has been a consultant at UCH for 20 years. He holds an academic appointment with UCL
Eastman and runs the post-graduate programme there. He is a world leader in the field of optical
diagnostics and photodynamic therapy for head and neck cancer and congenital malformations such as
lymphangioma, haemangioma and neurofibroma.
Research interests Photodynamic therapy in the treatment of head and neck cancer with around 1,000 treatments over the last 18 years. Publications MR imaging-­‐guided interstitial photodynamic laser therapy for advanced head and neck tumours. Jäger HR, Taylor MN, Theodossy T, Hopper C. AJNR Am J Neuroradiol. 2005 May; 26(5):1193-­‐200 Interstitial photodynamic therapy as salvage treatment for recurrent head and neck cancer. Lou PJ, Jäger HR, Jones L, Theodossy T, Bown SG, Hopper C. Br J Cancer. 2004 Aug 2;91(3):441-­‐6 mTHPC-­‐mediated photodynamic therapy for early oral squamous cell carcinoma. Hopper C, Kűbler A, Lewis H, Tan IB, Putnam G. Int J Cancer. 2004 Aug 10;111(1):138-­‐46 The cost-­‐effectiveness of Foscan mediated photodynamic therapy (Foscan-­‐PDT) compared with extensive palliative surgery and palliative chemotherapy for patients with advanced head and neck cancer in the UK. Hopper C, Niziol C, Sidhu M. Oral Oncol. 2004 Apr;40(4):372-­‐82 Photodynamic therapy: a clinical reality in the treatment of cancer. Hopper C. Lancet Oncol. 2000 Dec;1:212-­‐9 Photodynamic therapy using mTHPC for malignant disease in the oral cavity. Fan KF, Hopper C, Speight PM, Buonaccorsi GA, Bown SG. Int J Cancer. 1997 Sep 26;73(1):25-­‐32 Photodynamic therapy: an effective, but non-­‐selective treatment for superficial cancers of the oral cavity. Grant WE, Speight PM, Hopper C, Bown SG. Int J Cancer. 1997 Jun 11;71(6):937-­‐42 Photodynamic therapy using 5-­‐aminolevulinic acid for premalignant and malignant lesions of the oral cavity. Fan KF, Hopper C, Speight PM, Buonaaccorsi G, MacRobert AJ, Bown SG. Cancer. 1996 Oct 1;78(7):1374-­‐83 Horvath, Theodor A (M.D., Ph.D.)
Email: [email protected]
Education:
1973-1975 Medical School of Komensky University Martin SK
1975-1979 Charles University Medical School Prague CZ
1983 Graduated in General Surgery Prague CZ
1990 Graduated in Thoracic Surgery Prague CZ
1996-2000 Thoracic oncology postgraduate study CZ; Japan Masaryk
University Brno,Tokyo Medical University
2000 Graduated in Thoracic Surgical Oncology Ph.D.
Position:
1979 Dept. of General Surgery University Hospital Martin SK
1980-1983 Dept. General Surgery Hospital Česká LÃpa CZ
1983-1990 Dept. of Thoracic Surgery Hospital Ústà nad Labem CZ
1991-1992 Cardiocentre Brno CZ, Dept. of Surgery Klinikum rechts der Isar Munich D, Dept. of
Thoracic and Hyperbaric Surgery University Hospital Graz, A.
1992-1998 Dept. of Surgery Masaryk Memorial Cancer Institute Brno.
1998 - Consultant thoracic surgeon of Dept. of Surgery Faculty Hospital of Masaryk University BrnoBohunice
2001 - Consultant Thoracic Surgeon and Bronchologist (SAFE) of Masaryk Memorial Cancer Institute
Brno CZ and University Oncology Center Brno CZ
2001- Early Lung Cancer Initiative co-promoter
Biography:
Attending/consultant thoracic surgeon acting in General Thoracic Service of Masaryk University
Medical School Brno on Department of Surgery of Faculty Hospital Bohunice and in Sugical Oncology
Thoracic Service of Masaryk Memorial Cancer Institute Brno, author of Czech National Standards for
Surgery of Lung Cancer. Among his merits posture establishment of autofluorescence bronchoscopy in
Czech space, initiation of Early Lung Cancer Program C34_CIS dedicated to the issue of lung
carcinogenesis in central and peripheral location, comprehensive work Early Stage Lung Cancer from
the viewpoint of surgical oncology and especially cofounding of the platform Chest Brno Concept
Vznik focusing early lung cancer diagnosis, therapy,research and educational activity under one roof.
Fellowship: Czech and Slovak Surgical Society, Czech Medical Association of Jan Evangelist
Purkynje, International Photodynamic Association, American Society for Laser Medicine and Surgery,
European Society of Thoracic Surgeons, Charter Member of Editorial Board of the Elsevier Science
journal Photodiagnosis and Photodynamic Therapy and Personal interests: family, poetry, nature.
PUBLICATIONS
1. Detection of Bronchial Neoplasia in Uranium Miners by Autofluorescence Endoscopy (SAFE1000), Diagnostic and Therapeutic Endoscopy 1999;5:91-98.
2. The changes in early stage bronchial intraepithelial neoplasia (IEN) in uranium miners in a one-year
period with special reference to autofluorescence endoscopy (SAFE-1000). Lung Cancer 2000; 29:
Supp1, 255.
3. Autofluorescence (safe) bronchoscopy and p21/ki97 immunostaining related to carcinogenesis,
Photodiagnosis and Photodynamic Therapy 2004;1:13-22.
4. Logical response to early diagnosis means early intervention. Lasers in Surgery and Medicine 2005;
Supp17, 201.
5. Chirurgická léčba plicnÃch malignit. Surgical Treatment of Lung Malignancies. Klinická
onkologie 2005;18:226-229.
Jans, David A.
Nuclear Signalling Lab,
Department Of Biochem. & Mol. Biol.,
Monash University, P.o Box 13d,
Vic 3800,
Australia
Telephone:
Fax:
Email: [email protected]
Education:
After graduating (BSc. Hons) from the University of Melbourne Microbiology Dept. in 1980, he joined
the Dept. of Biochemistry at the John Curtin School of Medical Research (JCSMR) to carry out his
Ph.D. studies with Graeme Cox and Frank Gibson on bacterial ATPase (completed 1984).
Position:
David Andrew Jans is a Senior Principal Research Fellow of the National Health and Medical Research
Council.
He holds a personal chair within the Dept. of Biochemistry and Molecular Biology at Monash
University, where he is head of the Nuclear Signalling Lab.
Biography:
He then took up a research scientist position at the Friedrich Miescher Institut in Basel (Switzerland),
followed by a visiting fellowship at the Max Planck Institut for Biophysik in Frankfurt am Main
(Germany), working in the area of phosphorylation and signal transduction in mammalian cells.
In 1990, he became a Senior Scientist at the Institut für Medizinische Physik und Biophysik,
Westfälische Wilhelms-Universität in Münster (Germany), turning his interest to the use of confocal
microscopic techniques such as fluorescence recovery after photobleaching (FRAP) to investigate
transport processes.
He returned in 1993 to the JCSMR (Division of Biochem. & Mol. Biol.) to establish the Nuclear
Signalling Lab, with a strong focus on the processes of protein transport into the eukaryotic cell
nucleus, becoming a Full Professor in 2000, before his move to his present position at Monash
University in 2001.
He has also held a conjoint appointment at the James Cook University of North Queensland
(Townsville) since 1998. He has received a number of awards, including the IRPC (International
Research Progress Council) Eminent Scientist of the Year Award for Molecular Biology in 1999, and
the GE Healthcare Bio-Sciences Award (ASBMB) in 2005, and was a Danny Thomas Lecture Series
Visiting Professor (St. Jude's Hospital, Memphis) in 2005.
He is also coauthor, with Prof. Alexander Sobolev and coworkers, of a patent ("A Composition to
Effect Photodynamic Damage of Target Cells and a Method to Effect Photodynamic Damage of Target
Cells" which won a Medaille d'Or avec Mention at the 45th. World Salon of Inventions - "Brussels Eureka 96").
His research over 20 years has spanned many aspects of signal transduction/phosphorylation, with an
emphasis on quantitative approaches, particularly in the application of confocal microscopy. His
current work is focused on the transport of molecules into the nucleus in normal and disease (eg. viral
infection) states, the regulation thereof, and how this may be applied to nuclear drug delivery/gene
therapy.
Recent work has included the application of FRAP to examine nucleocytoplasmic flux in single living
cells, and role therein of the cytoskeleton, and the demonstration of the central role of the regulation of
nuclear transport in development.
With respect to the latter, his recent research has defined the nuclear import pathway of the sexdetermining factor SRY, and documented the first cases of impaired development (XY sex reversal) in
humans being explained by a failure of nucleocytoplasmic trafficking. His lab. has also recently
determined the signals responsible for tumor cell-specific nuclear targeting of a pro-apoptotic viral
protein (CAV VP3).
His continuing research interests are aimed at seeking to understand how the regulation of nuclear
transport impacts on viral disease and development, together with the application of this knowledge in
non-viral gene delivery and tumor cell-specific delivery of nuclear acting drugs such as
photosensitisers.
Kessel, David(PhD)
Wsu School Of Medicine, Department Of Pharmacology
540 East Canfield Avenue
Detroit
Michigan, 48201
U.s.a.
Telephone:
Fax:
Email: [email protected]
Education:
BS from MIT (Chemistry) , MS from University of Michigan (Chemistry) and PhD (Biological
Chemistry).
Position:
Post Doc at Harvard Medical School.
Associate Prof of Pharmacology (University of Rochester).
Prof of Pharmacology & Medicine at Wayne State University since 1974.
Korbelik, Mladen(Ph.D.)
British Columbia Cancer Agency Cancer Imaging Department British
Columbia Cancer Research Centre
675 West 10th Avenue
Vancouver
B.c.
Canada
V5Z 1L3
Email: [email protected]
Education:
He has a B.Sc. degree in Chemistry (1970) and Ph.D. degree in Biology (1979) both received from the
University of Zagreb, Croatia.
Position:
Dr. Mladen Korbelik is a Senior Scientist in the British Columbia Cancer Agency in Vancouver, B.C.,
Canada and a Clinical Professor in the Department of Pathology & Laboratory Medicine (Faculty of
Medicine) of the University of British Columbia.
Awards:
By 2007 he has published 85 peer-reviewed scientific papers, 24 non-refereed papers, 16 book
chapters, 41 published abstracts with a total of 153 presentations at scientific conferences (40 as an
invited speaker). He has served as a panel member and reviewer for various scientific granting agencies
in Canada, USA and elsewhere.
Biography:
A major focus of Dr. Korbelik's research since 1987 has been the investigation of the mechanism of
antitumor effects of photodynamic therapy (PDT).
The research in his laboratory has contributed to the understanding of photosensitizer accumulation in
tumors, particularly the role of serum proteins, tumor vasculature and tumor associated macrophages in
this event. His work has shown that PDT treatment of solid cancers elicits a strong host response,
which contributes to the therapy outcome. His findings include providing direct evidence of the
induction of tumor immunity by PDT and demonstrating that PDT can be effectively potentiated by
different types of adjuvant immunotherapy.
Dr. Korbelik is actively engaged in the development of PDT-generated cancer vaccines.
Kostron, Herwig(M.D.)
Department Of Neurosurgery, University Innsbruck
Anichstrasse 35
A 6020
Innsbruck
Austria
Email: [email protected]
Education:
Education and Medical School, Graz, Austria 1968-1974
Fellow at Dept. Biochemical Pharmacology 1974/75
1976-1982 Dept. Neurosurgery Innsbruck
1982-83 Research Fellow at Mass. General Hospital/ Harvard Medical School
various training courses in USA and Europe
1987 Assistant Professor, Venia Docendi
1994 Associate Professor
Position:
Associate Professor and Senior Neurosurgeon at Dept. Neurosurgery,
Medical University Innsbruck
Head of Neuro-oncology, Dept Neurosurgery
Head of Photodynamic Research group, Univ. Innsbruck
Awards:
Scientific awards: 5
Publications 176 (JCR 97, 5; Citations index >450)
>2150 Tumor craniotomies
>9000 general neurosurgical Procedures
Advisory Board IPA, ESP, ENS
Honory medical doctor of the University of Tbilisi, Georgia
Director of International Photodynamic Association
Biography:
Memberships:
Austrian/German Neurosurgical Societies
Central European Neurosurgical Society
European Neuro-oncology Society
International Photodynamic Association- IPA
EORTC
Special Interest:
Neuro-oncology,
Clinical neuro-oncological Trials
Photodynamic applications for Neurosurgery since 1982
Intraoperative Fluorescence /Tumordelineation since 1989
Experimental local and systemic therapies
Transvection enhanced intratumoral Fusionproteins
+ Moseley, Harry, PhD
Tel. 01382 496227 (office)
E-mail: [email protected]
PROFESSIONAL QUALIFICATIONS
BSc, Glasgow
PhD, Glasgow
MBA, Strathclyde
CAREER HISTORY
Since May 1996:
Consultant Clinical Scientist
Head of Scientific Services
The Photobiology Unit
Ninewells Hospital & Medical School
Dundee
PROFESSIONAL REGISTRATION
Health Professions Council
CS.01615
RESEARCH TRAINING
ICH GCP training course 12/04/2006
Research Governance update seminar
26/08/2008
Pogue, Brian William
Thayer School Of Engineering
Dartmouth College 8000 Cummings Hall
Hanover
Nh 03755
Usa
Email: [email protected]
Education:
York University, ON, Canada B.Sc. Hons. 1985-1989 Physics
York University, ON, Canada M.Sc. 1989-1991 Physics
McMaster University, ON, Canada Ph.D. 1991-1996 Medical Physics
Harvard Medical School/ Research Fellow 1995-1996 Photobiology/Photochemistry Massachusetts
General Hospital
Position:
Associate Professor of Engineering Sciences
Director, M.S. and Ph.D Programs, Engineering
Biography:
09/96 -12/96 Adjunct Instructor: Quincy College, Quincy, MA.
12/96 - 09/00 Visiting Research Fellow: Wellman Laboratories of Photomedicine, Mass. General
Hospital, Dept. of Dermatology, Harvard Medical School, Boston, MA
12/96 - 6/01 Research Assistant Professor: Thayer School of Engineering, Dartmouth College,
Hanover, NH.
03/97- present Member, Radiation/Bioengineering Group, Norris Cotton Cancer Center, Lebanon NH.
10/00 - present Lecturer, Harvard Medical School, Department of Dermatology, Boston, MA.
10/00 - present Research Scientist, Wellman Center for Photomedicine, Mass. General Hospital,
Boston, MA
07/01 - present Associate Professor, Thayer School of Engineering, Dartmouth College, Hanover NH.
09/07 - present Adjunct Associate Professor, Department of Surgery, Dartmouth Medical School.
09/05 - present Director, M.S. and Ph.D. Programs, Thayer School of Engineering, Dartmouth College.
• Writer & Reviewer of questions on MCAT exam, American Institute for Research, (1996 - 2006).
• Topical Editor of Optics Letters for all papers in the fields of medicine and biology (7/00 - 7/06).
• Deputy Editor, Optics Letters, published by the Optical Society of America (2008-present).
• Editorial Board Medical Physics, published by the AAPM (2006-present).
• Editorial Board, Journal of Biomedical Optics, published by SPIE (2007-present).
• Editor of textbook Fluorescence in Biomedicine, Marcel Dekker Publ., (2003).
Honors
• Graduate Studies Mentoring Award, Dartmouth College, 2006.
• Engineering Foundation Conference Fellowship Award, 1997, 1999.
• Gordon conference competitive award for post-doctoral registrants, 1996.
• Hamilton Civic Hospitals Radiology Graduate Research Presentation Prize, 1992.
• York University Entrance Tuition Scholarship, 1989.
Selected peer-reviewed publications (from over 120 peer-reviewed publications).
Pogue BW, Hasan T, "A theoretical examination of light fractionation and dose rate effects in
photodynamic therapy," Radiation Research 147, 551-559, 1997.
Pogue BW, Burke G, "Fiber optic bundle design for non-invasive quantitative fluorescence
measurements from tissue-simulating media," Applied Optics, 37(31) 7429-7436 (1998).
Pogue BW, Burke G, "Fiber optic bundle design for non-invasive quantitative fluorescence
measurements from tissue-simulating media," Applied Optics, 37(31) 7429-7436 (1998).
Pogue BW, Paulsen KD, "High resolution near infrared tomographic imaging simulations of rat
cranium using apriori MRI structural information," Optics Letters 23(21) 1716-8, (1998).
Pogue BW, Momma T, Wu H, Hasan T, "Investigation of transient absorption in vivo during
photodynamic therapy with pulsed laser light," Br. J. Cancer 80(3-4) pp.344-351, (1999).
Pogue BW, Redmond RW, Chen N, Ortel B, Hasan T, "A Photobiological and Photophysical-Based
Study of Phototoxicity of two chlorines," Cancer Rearch.61, 717-24, 2001.
Pogue BW, McBride TO, Osterman S, Poplack SP, Osterberg U, Paulsen KD, "Quantitative
Hemoglobin Tomography Diffuse Near-Infrared Spectroscopy: Pilot Results in the Breast," Radiology,
218(1), 261-6, 2001.
Pogue BW, O'Hara J, Wilmot C, Paulsen KD, Swartz H, "Estimation of capillary oxygen concentration
in RIF-1 tumors with model-based interpretation of hypoxia & Eppendorf measurement," Rad. Res.
155, 15-25, 2001.
Pogue BW, Braun R, Lanzen J, Erickson C, Dewhirst MW, "Acute Tissue (pO2) and Blood Flow
Dynamics during Photodynamic Therapy with Verteporfin," Photochemistry and Photobiology, 74(5)
700-706, (2001).
Srinivasan S, Pogue BW, Jiang S, Dehghani H, Kogel C, Soho S, Gibson JJ, Tosteson TD, Poplack SP,
Paulsen KD, "Interpreting Hemoglobin and Water Conc., Oxygen Saturation, and Scattering Measured
by Near-Infrared Tomography of Normal Breast In Vivo," PNAS USA, 100(21) 12349-12354 (2003).
Chen B, Pogue BW, Goodwin IA, O'Hara JA, Wilmot CM, Hutchins JE, Hoopes PJ, Hasan T, "Blood
Flow Dynamics Following Photodynamic Tx with verteporfin in RIF-1 Tumor," Radiat. Res. 160, 452459 (2003).
Pogue BW, O'Hara JA, Demidenko E, Wilmot CJ, Goodwin IA, Chen B, Swartz HM, Hasan T, "NonVascular Targeting Photodynamic Therapy of the RIF-1 Tumor with Verteporfin Causes Enhanced
Radiation Sensitivity," Cancer Research, 63,1025-1033 (2003).
Dehghani H, Pogue BW, Jiang S, Brooksby B, Paulsen KD, "Three-dimensional optical tomography:
resolution in small-object imaging," Applied Optics 42(16) 3117-3128 (2003).
Pogue BW, Jiang S, Dehghani H, Kogel C, Soho S, Srinivasan S, Song X, Tosteson TD, Poplack SP,
Paulsen KD, "Characterization of Hemoglobin, Water and NIR Scattering in Breast Tissue: Analysis of
inter-subject variability and menstrual cycle changes," Journal of Biomedical Optics, 9(3), 541-552
(May/June 2004).
Pogue BW, Gibbs SL, Chen B, Savellano M, "Fluorescence Imaging In Vivo: Raster Scanned PointSource Imaging Provides More Accurate Quantification than Broad Beam Geometries," Technology in
Cancer Research and Treatment 3(1) 15-21 (2004).
Chen B, Pogue BW, Hoopes PJ, Hasan T, "Combining vascular and cellular targeting regimens
enhances the therapeutic effect of photodynamic therapy," Int. J. Radiation Oncol. Biol. Phys., 61(4)
12-16-1226, (2005).
Pogue BW, Jiang S, Dehghani H, Kogel C, Soho S, Srinivasan S, Song X, Tosteson TD, Poplack SP,
Paulsen KD, "Characterization of Hemoglobin, Water and NIR Scattering in Breast Tissue: Analysis of
inter-subject variability and menstrual cycle changes," Journal of Biomedical Optics, 9(3) 541-552
(2004).
Poplack SP, Paulsen KD, Hartov A, Meaney PM, Pogue BW, Tosteson TD, Grove MR, Soho SK,
Wells WA, "Electromagnetic Breast Imaging: Average Tissue Property Values in Women with
Negative Clinical Findings," Radiology 231(2) 571-580 (2004).
Chen, B., Pogue, B. W., Hoopes, P. J., Hasan, T. "Combining vascular and cellular targeting regimens
enhances the therapeutic effect of photodynamic therapy" International Journal of Radiation Oncology,
Biology, Physics, 61(4) 1216-1226 (2005).
Chen, B., Pogue, BW, Hasan, T, "Liposomal Delivery of Photosensitizing Agents" Expert Opinion on
Drug Delivery, 2(3) 477-487 (2005).
del Carmen, MG, Rizvi, I, Moor, ACE, Oliva, E, Chang, Y, Pogue, BW and Hasan, T, "Epidermal
Growth Factor Receptor Targeted Immunotherapy is Synergistic with Photodynamic Treatment of
Ovarian Cancer In Vivo", Journal of the National Cancer Institute, 97(20) 1516-1524 (2005).
Chen, B., Pogue, B. W., Luna, J. M., Hardman, R. L., Hoopes, P. J., Hasan, T., "Tumor vascular
permeabolization by vascular targeting photosensitization: effects, mechanism and therapeutic
implications" Clinical Cancer Research, 12(3) 917-923 (2006).
Zhou, X., Pogue, B. W., Chen, B., Demidenko, E., Joshi, H., Hoopes, P. J., Hasan, T., "Pretreatment
photosensitizer dosimetry reduces variation in treatment response" International Journal of Radiation
Oncology Biology Physics, 64(4) 1211-1220 (2006).
Dehghani, H., Davis, S., Jiang, S., Pogue, B. W., Paulsen, K. D., "Spectrally-resolved bioluminescence
optical tomography" Optics Letters 31(3) 365-367 (2006).
Brooksby, B., Pogue, B. W., Jiang, S., Dehghani, H., Srinivasan, S., Kogel, C., Tosteson, T. D.,
Weaver, J., Poplack, S. P., Paulsen, K. D., "Imaging Breast Adipose and Fibroglandular Tissue
Molecular Signatures using Hybrid MRI-Guided Near-Infrared Spectral Tomography" Proceedings of
the National Academy of Sciences, 103(23) 8828-8833 (2006).
Research Support.
Ongoing Research
PO1 CA80139 (Paulsen) 05/01/06 - 04/30/11 NIH "Near-Infrared Spectroscopy and Imaging" within
program project "Alternative Breast Cancer Imaging Modalities" This project focuses on the
technological development of a near-infrared imaging system which can sample signals transmitted
through breast tissue and image hemoglobin-related. Role: PI of Project 4
PO1 CA84203 (Hasan) 08/01/01 - 07/31/07 (renewal in progress) Subcontract through Massachusetts
General Hospital (NIH) "Online-measurement and Model-based PDT dosimetry" within program
project "Biological and Physical Determinants for Optimal PDT" This program looks at methods to
improve the treatment of displastic tissues with photodynamic therapy. The biological and physical
conditions that affect treatment efficacy are examined in murine models and in human clinical trials.
The component on dosimetry (P.I. Pogue) examines the development of dosimetry tools that can
provide fundamentally new information about dose in tissue. Role : Consortium PI
R01 CA109558 05/01/05 - 03/31/10 NIH "Fluorescence Imaging to Optimize Cancer Therapy" The
goal of this project is to develop and utilize NIR fluorescence imaging of protoporphyrin IX induced by
administration of aminolevulinic acid as a measurement of tumor metabolism, to monitor changes in
response to therapy, examining the effects of radiation therapy, chemotherapy and photodynamic
therapy. Role: PI
R01 CA120368 02/12/07 - 01/31/12 NIH "Micro CT/NIR Molecular Imaging of Cancer" The goal of
this project is to develop and utilize MicroCT guided NIR luminescence tomography to image vascular
and cellular networks within tumor tissue, using luminescent reporters in vivo. Role: PI
U54 CA105480 (Tromberg, UC Irvine) 09/23/03 - 08/31/08 NIH "Spatial/Spectral Tomography for
Localized Functional Spectroscopy" subcontract project title within "Breast Cancer Multi-dimensional
Diffuse Optical Imaging" The goal of this work is to develop diffuse tomography guided NIR
spectroscopy of breast tissue, and to contribute NIR technology ideas towards a future multicenter
study in breast disease. This project is centered through UCI, and subcontracts out to MGH, U Penn
and Dartmouth. Role: Consortium PI
R21/R33 CA100984 05/01/04 - 07/31/08 NIH "Spectral-Encoding for Video-Rate Hemodynamic
Tomography" The goal of this project is to develop and utilize NIR tomography at 30 Hz frame rate,
allowing visualization of images of blood and water changes in tissue. The R21 phase of the grant is
proof of feasibility of imaging tissue phantoms quantitatively at video rate and in vivo image
acquisition at video rate. Role: PI
Philips Sponsored Research Agreement 01/01/06 - 12/31/07 Philips Medical Research "Analysis of
Combined MRI and Fluorescence Optical Tomography" This project is focused on developing an
optimized small animal and breast cancer tomography system within the 3T MRI unit. Role: PI
Completed Research Support (in the last 3 years)
R43CA105650 05/01/05 - 03/31/06 Radiation Monitoring Devices (NIH SBIR subcontract) "Cancer
Detection Using Luminescent Imaging" This project focuses on development of antibody bound
oxygen sensitive phosphors to image oxygen concentration in vivo. Role: PI
ART Sponsored Research Agreement 05/09/05 - 03/31/07 ART (Advanced Research Technologies),
Inc. "Time Domain (TD) Optical Imaging Technology Platform" This project is a sponsored agreement
with ART Inc. to help calibrate their systems and assist with computer simulations to optimize imaging
procedures. Role: PI
RO1 CA69544 (Paulsen) 12/01/02 - 11/30/06 NIH "Frequency Domain Optical Imaging of Breast
Cancer" This grant examines the potential of combining NIR imaging with MRI breast examination to
enhance the image reconstruction and diagnostic potential of NIR tomography. Role: Co-Investigator
Robinson, Dominic J. (Ph.D)
Center For Optical Diagnostics And Therapy Department Of Radiation
Oncology
Room Wk-319
Erasmus Mc
3000 Ca Rotterdam
The Netherlands
POBox 2040
Email: [email protected]
Education:
Ph.D. 1998. University of Leeds, Leeds, United Kingdom; In-vivo kinetics of photosensitiser
fluorescence during photodynamic therapy.
Position:
Assistant Professor of Radiation Oncology, Center for Optical Diagnostics and Therapy, Department of
Radiation Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Biography:
BRIEF STATEMENT OF RESEARCH INTERESTS:
Dr. Dominic Robinson has a research program centred on photodynamic therapy that encompasses 3
main themes. Understanding the mechanism of action of underlying (pre-) clinical PDT using the
porphyrin pre-cursors and mTHPC and the clinical optimisation of therapy in Dermatology,
Gastroenterology and in Head and Neck cancer. Researching the theoretical basis and developing
technology for photodynamic therapy dosimetry and monitoring treatment and the investigation of
receptor targeted photodynamic therapy. Research in our laboratories is currently funded by the Dutch
Cancer Society (KWF), Dutch Technology Foundation (STW), The National Institutes for Health
(NIH), Medical Delta and the European Union.
SELECTED PUBLICATIONS:
1. de Bruijn HS, de Haas ER, Hebeda KM, van der Ploeg-van den Heuvel A, Sterenborg HJ, Neumann
HA, Robinson DJ. Light fractionation does not enhance the efficacy of methyl 5-aminolevulinate
mediated photodynamic therapy in normal mouse skin. Photochem Photobiol Sci. 2007;6:1325-31.
2. de Bruijn HS, Kruijt B, van der Ploeg-van den Heuvel A, Sterenborg HJ, Robinson DJ. Increase in
protoporphyrin IX after 5-aminolevulinic acid based photodynamic therapy is due to local re-synthesis.
Photochem Photobiol Sci. 2007;6:857-64.
3. de Haas ER, Kruijt B, Sterenborg HJ, Martino Neumann HA, Robinson DJ. Fractionated
illumination significantly improves the response of superficial basal cell carcinoma to aminolevulinic
acid photodynamic therapy. J Invest Dermatol. 2006;126:2679-86.
4. Kruijt B, de Bruijn HS, van der Ploeg-van den Heuvel A, Sterenborg HJ, Robinson DJ. Laser
speckle imaging of dynamic changes in flow during photodynamic therapy. Lasers Med Sci.
2006;21:208-12.
5. van Veen RL, Robinson DJ, Siersema PD, Sterenborg HJ. The importance of in situ dosimetry
during photodynamic therapy of Barrett's esophagus. Gastrointest Endosc. 2006;64:786-8.
6. Boere IA, Robinson DJ, de Bruijn HS, Kluin J, Tilanus HW, Sterenborg HJ, de Bruin RW.
Protoporphyrin IX fluorescence photobleaching and the response of rat Barrett's esophagus following
5-aminolevulinic acid photodynamic therapy. Photochem Photobiol. 2006;82:1638-44.
7. de Bruijn HS, Sluiter W, van der Ploeg-van den Heuvel A, Sterenborg HJ, Robinson DJ. Evidence
for a bystander role of neutrophils in the response to systemic 5-aminolevulinic acid-based
photodynamic therapy. Photodermatol Photoimmunol Photomed. 2006;22:238-46.
8. van Veen RL, Nyst H, Rai Indrasari S, Adham Yudharto M, Robinson DJ, Tan IB, Meewis C, Peters
R, Spaniol S, Stewart FA, Levendag PC, Sterenborg HJ. In vivo fluence rate measurements during
Foscan-mediated photodynamic therapy of persistent and recurrent nasopharyngeal carcinomas using a
dedicated light applicator. J Biomed Opt. 2006;11:041107.
9. Amelink A, van der Ploeg van den Heuvel A, de Wolf WJ, Robinson DJ, Sterenborg HJ. Monitoring
PDT by means of superficial reflectance spectroscopy. J Photochem Photobiol B. 2005;79:243-51.
10. Boere IA, Robinson DJ, de Bruijn HS, van den Boogert J, Tilanus HW, Sterenborg HJ, de Bruin
RW. Monitoring in situ dosimetry and protoporphyrin IX fluorescence photobleaching in the normal
rat esophagus during 5-aminolevulinic acid photodynamic therapy. Photochem Photobiol.
2003;78:271-7.
11. Robinson DJ, de Bruijn HS, Star WM, Sterenborg HJ. Dose and timing of the first light fraction in
two-fold illumination schemes for topical ALA-mediated photodynamic therapy of hairless mouse
skin. Photochem Photobiol. 2003;77:319-23.
12. Topical 5-aminolevulinic acid-photodynamic therapy of hairless mouse skin using two-fold
illumination schemes: PpIX fluorescence kinetics, photobleaching and biological effect. Photochem
Photobiol. 2000;72:794-802.
13. Robinson DJ, Collins P, Stringer MR, Vernon DI, Stables GI, Brown SB, Sheehan-Dare RA.
Improved response of plaque psoriasis after multiple treatments with topical 5-aminolaevulinic acid
photodynamic therapy. Acta Derm Venereol. 1999;79:451-5.
14. de Bruijn HS, van der Veen N, Robinson DJ, Star WM. Improvement of systemic 5-aminolevulinic
acid-based photodynamic therapy in vivo using light fractionation with a 75-minute interval. Cancer
Res. 1999;59:901-4.
15. Robinson DJ, de Bruijn HS, van der Veen N, Stringer MR, Brown SB, Star WM. Protoporphyrin
IX fluorescence photobleaching during ALA-mediated photodynamic therapy of UVB-induced tumors
in hairless mouse skin. Photochem Photobiol. 1999;69:61-70.
16. Robinson DJ, de Bruijn HS, van der Veen N, Stringer MR, Brown SB, Star WM. Fluorescence
photobleaching of ALA-induced protoporphyrin IX during photodynamic therapy of normal hairless
mouse skin: the effect of light dose and irradiance and the resulting biological effect. Photochem
Photobiol. 1998;67:140-9.
Usuda, Jitsuo
Department Of Thoracic Surgery Tokyo Medical University
6-7-1 Nishishinjuku
Shinjkuku-ku
Tokyo 160-0023
Japan
Email: [email protected]
Education:
2000 Ph.D., Tokyo Medical University
1994 M.D., Tokyo Medical University
Position:
2007-present Assistant Professor in Department of Thoracic Surgery, Tokyo Medical University
2003-2007 Staff doctor in Department of Surgery, Tokyo Medical University Hospital
2002-2003 Research Associate in Department of Radiation Oncoloy, School of Medicine, Case
Western Reserve University
2001-2002 Research Scholar in Department of Radiation Oncology, School of Medicine, Case Western
Reserve University
2000-2001 Staff doctor in Department of Surgery, Tokyo Medical University Hospital
1998-2000 Clinical fellow in Department of Surgery, Tokyo Medical University Hospital
1996-1998 Research resident, Pharmacology Division, National Cancer Center, Research Institute
1994-1996 Resident in Department of Surgery, Tokyo Medical University Hospital
1994 Passed the Examination of National Board
Awards:
Award in 2007 Congress Award from Japanese Association for Bronchology (Ohata memorial award)
Award in 2006 Congress Award from International Academy Laser Medicine and Surgery (IALMS)
Award in 2005 Congress Award from Japanese Society for Loco-Regional Cancer Therapy
Award in 2004 Investigating Award from Tokyo Medical Association
Award in 2000 Sasa memorial award (Tokyo Medical University)
Grant in 2006, 2007 Grant-in-Aid for Young Scientist (B) from the Ministry of Education, Culture,
Sports, Science and Technology (MEXT).KAKENHI 18791002
Grant in 2004, 2005 Grant-in-Aid for Young Scientist (B) from the Ministry of Education, Culture,
Sports, Science and Technology (MEXT).KAKENHI 16790802
Grant in 2007 Grant-in-Aid for Cancer Research from Tokyo Medical University
Biography:
License and Certification :
Japanese Medical License Registration Diplomat, Japanese Board of General Surgery
Diplomat, Japanese Board of Chest sugery
Diplomat, Japanese Board of Bronchology
Diplomat, Japanese Board of Laser surgery and Medicine
Diplomat, Japanese Board of Clinical Oncology
Diplomat, Japanese Board of Clinical cytology
Publications:
1. Usuda J., Ohtani K., Ichinose S., Ishizumi T., Hirata T., Inoue T., Maehara S., Imai K., Kubota M.,
Tsunoda Y., Yamada M., Tsutsui H., Yamada K., Kuroiwa Y., Furukawa K., Okunaka T, Kato H. High
expression of GADD-45-alpha and VEGF induced tumor recuurence via upregulation of IL-2 after
photodynamic therapy using NPe6. Int J Oncology: 32; 397-403, 2008
2. Usuda J., Ohira T., Suga Y., Oikawa ., Ichinose S., Inoue T., Ohtani K., Maehara S., Imai K., Kubota
M., Tsunoda Y., Furukawa K., Okunaka T., and Kato H. Breast cancer resistance protein (BCRP)
affected acquired resistance to Gefitinib in a never-smoking woman with advanvanced lung cancer.
Lung Cancer :58; 296-299, 2007
3. Usuda J., Okunaka T., Ichinose S., Hirata T., Inoue T., Ohtani K., Imai K., Kubota M., Tsunoda Y.,
Kuroiwa Y., Tsutsui H., Furukawa K and Kato H.: Photodynamic therapy using a novel
photosensitizer, ATX-s10Na(II) caused anti-cancer activity independing upon expression of vascular
endothelial growth factor in vivo. Oncol. Rep. :18; 679-683, 2007
4. Usuda, J., Tsutsui H., Honda, H., Suga, Y., Ichinose, S., Hirata, T., Ohtani, K., Inoue, T., Maehara,
S., Imai, K., Tsunoda, Y., Kubota, M., Ikeda, N., Furukawa, K., Okunaka, T. and Kato, H. :
Photodynamic therapy for lung cancers based on novel photodynamic diagnosis using talaporfin
sodium (NPe6) and autofluorescence bronchoscopy. Lung Cancer : 58; 317-323, 2007
5. Usuda, J., Kato, H., Okunaka, T., Furukawa, K., Honda, H., Tsutsui, H., Yamada, K., Suga, Y.,
Ohira, T., Tsuboi, M., Hirano, T.: Photodynamic therapy for lung cancers. J Thorac. Oncol.: 1, 489493, 2006
6. Usuda, J., Azizuddin, K., Chiu, S. M. and Oleinick, N.: Association between the photodynamic loss
of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy. Photochem.
Photobiol. : 78,1-10, 2003
7. Usuda, J., Nishio, K., Fukuoka, K., Iwamoto, Y., Kato, H. and Saijo, N.: Restoration of p53 gene
function in 12-O-tetradecanoylphorbor 13-acetate (TPA)-resistant human leukemia K562/TPA cells.
Int. J. of Oncology:: 22, 81-86, 2003
8. Usuda, J., Chiu, S. M., Xue, L. Y., Lam, M., Nieminen, A. L. and Oleinick, N. L.: Domain-specific
photodamage to Bcl-2; A membrane-anchorage region is the target of phthalocyanine
photosensitization. J. Biol. Chem.: 278, 2021-2029, 2003
9. Usuda, J., Chiu, S. M., Azizuddin, K., Xue, L. Y., Lam, M., Nieminen, A. L., and Oleinick, N. L. :
Promotion of photodynamic therapy-induced apoptosis by the mitochondrial protein Smac/DIABLO :
Dependence on Bax. Photochem. Photobiol. : 76, 217-223, 2002
10. Usuda, J. and Kato, H.: Meeting Report: 30th Annual Meeting of the American Society for
Photobiology. PDT News: 5, 9, 2002
11. Usuda J., Okunaka T., Furukawa K., Kuroiwa Y., Saijo N., Konaka C., Kato H.: Increased
cytotoxic effects of photodynamic therapy in IL-6 gene transfected cells via enhanced apoptosis. Int. J.
of Cancer : 93, 475-480, 2001
12. Usuda, J., Saijo, N., Fukuoka, K., Fukumoto, H., Tamura, T., Kato, H., Nishio, K.: Molecular
determinants of UCN-01-induced growth inhibition in human lung cancer cells. Int. J. of Cancer : 85,
275-280, 2000
13. Akata S., Yoshimira M., Park J., Okada S., Maehara S., Usuda J., Kajiwara N., Tsuboi M., Kato H.,
Kakizaki D. Glomus tumor of left main bronchus. Lung Cancer (in press), 2008
14. Tsuboi M., Ohira T., Saji H., Miyajima K., Kajiwara N., Uchida O., Usuda J., Kato H.: The present
status of postoperative adjuvant chemotherapy for completely resected non-small cell lung cancer. Ann
Thorac Cardiovasc Surg.: 13, 73-77, 2007
15. Ikeda N, Hayashi A, Iwasaki K, Honda H, Tsuboi M, Usuda J, Kato K. Comprehensive diagnosis
bronchoscopy of central type early stage lung cancer. Lung Cancer: 56, 295-302, 2007
16. Ichinose S., Usuda J., Hirata T., Inoue T., Ohtani K., Maehara S., Kubota M., Imai K., Tsunoda Y.,
Kuroiwa Y., Yamada K., Tsutsui H., Okunaka T., Oleinick N. L. and Kato H. : Lysosomal cathepsin
initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic
therapy using a novel photosensitize, ATX-s10(Na). Int. J. of Oncol.: 29, 349-355, 2006
17. Kato H, Usuda J, Okunaka T, Furukawa K, Honda H, Suga Y, Hirata T, Ohtani K, Kubota M,
Yamada K, Tsutsui H. The clinical studies and basic researches in Tokyo Medical University Hospital.
Lasers Surg Med: 38, 371-375, 2006
18. Ikeda N, Honda H, Hayashi A, Usuda J, Kato Y, Tsuboi M, Ohira T, Hirano T, Kato H. Early
detection of bronchial lesions using newly developed videoendoscopy-based autofluorescence
bronchoscopy. Lung Cancer : 52, 21-27,2006
19. Ohira T, Suga Y, Nagatsuka Y, Usuda J, Tsuboi M, Hirano T, Ikeda N and Kato H. Early-stage
lung cancer: diagnosis and treatment. Int J Clin Oncol 11, 9-12, 2006
20. Furukawa K., Kato H., Konaka C., Okunaka T., Usuda J. and Ebihara Y.: Locally recurrent centraltype early stage lung cancer < 1.0 cm in diameter after complete remission by photodynamic therapy.
Chest 128, 3269-3275, 2005
21. Sutedja G., Kato H. and Usuda J.: Bronchoscopic treatment of early lung cancer lesions. IASLC
textbook of prevention and detection of early lung cancer. 177-186, 2005
22. Kato H., Harada M., Ichinose S., Usuda J., Tsuchida T. and Okunaka T.: Photodynamic therapy
(PDT) of lung cancer: experience of the Tokyo Medical University. Photodiagnosis and Photodynamic
Therapy 1, 49-55, 2004
23. Kato H., Usuda J., Okunaka T. and Furukawa K.: The history of the study of Photodynamic therapy
(PDT) and Photodynamic diagnosis (PDD) in the department of Surgery, Tokyo Medical University.
Photodiagnosis and Photodynamic Therapy 1, 107-110, 2004
24. Chiu, S. M., Xue, L. Y., Usuda, J., Azizuddin, K. and Oleinick, N.: Bax is essential for
mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy. Br. J. of
Cancer 89, 1590-1597, 2003
25. Ohira, T., Akutagawa, S., Usuda, J., Nakamura, T., Hirano, T., Tsuboi, M., Nishio, K., Taguchi, F.,
Ikeda, N., Nakamura, H., Konaka, C. and Kato, H. : Up-regulated gene expression of angiogenesis
factors in post-chemotherapeutic lung cancer tissues determined by cDNA microarray. Oncol. Rep. 9,
723-728, 2002
26. Fukuoka, K., Arioka, H., Iwamoto, Y., Fukumoto, H., Kurokawa, H., Ishida, T., Tomonari, A.,
Suzuki, T., Usuda, J., Kanzawa, F., Saijo, N. and Nishio, K.: Mechanism of vinorelbine-induced
radiosensitization of human small cell lung cancer cells. Cancer Chemotherapy and Pharmacology, 49,
385-390, 2002
27. Fukuoka, K., Arioka, H., Iwamoto, Y., Fukumoto, H., Kurokawa, H., Ishida, T., Tomonari, A.,
Suzuki, T., Usuda, J., Kanzawa, F., Saijo, N. and Nishio, K.:Mechanism of Radiosensitization induced
by vinorelbine in human non-small cell lung cancer cells. Lung Cancer, 34, 451-460, 2001
28. Fukuoka, K., Usuda, J., Iwamoto, Y., Fukumoto, H., Nakamura, T., Yoneda, Y., Narita, N., Saijo,
N., Nishio, K.: Mechanism of action of the novel sulfonamide anticancer agent E7070 on cell cycle
progression in human non-small cell lung cancer cells. Invest. New Drugs, 19, 219-227, 2001
29. Furukawa, K., Kato, Y., Shimatani, H., Usuda, J., Miura, T., Konaka, C., Kato, H. and Ebihara, Y.:
Percutaneus microwave coagulation therapy for lung cancers. Journal of Microwave Surgery, 19, 5559, 2001
30. Kuh, H-J., Nakagawa, S., Usuda, J., Yamaoka, K., Saijo, N. and Nishio, K.: A computational
model for quantitative analysis of cell cycle arrest and its contribution to overall growth inhibition by
the anticancer agents. Jpn. J. Cancer Res., 91, 1303-1313, 2000
31. Fukuoka, K., Nishio, K., Arioka, H., Kurokawa, H., Ishida, T., Usuda, J., Narita, N., Saijo, N.:
Ectopic p16(ink 4) expression enhances CPT-11-induced apoptosis through increased S-phase
progression in human non-small cell lung cancer cells. Int. J. of Cancer 86, 197-203, 2000
32. Fukumoto, H., Tamura, T., Kamiya, Y., Usuda, J., Suzuki, T., Ohe, Y., Saijo, N. and Nishio, K.:
Activation-induced apoptosis of peripheral lymphocytes treated with UCN-01. Invest. New Drugs, 17,
335-341, 2000
33. Okunaka, T., Furukawa, K., Tsutsui, H., Usuda, J., Nitadori, J., Kato, Y., Kuroiwa, Y., Konaka, C.
and Kato, H.: Photodynamic therapy for early and advanced stage bronchogenic carcinoma. Journal of
the Japan society for bronchology, 22, 636-639, 2000
34. Nishio, K., Fukuoka, K., Fukumoto, H., Iwamoto, Y., Suzuki, T., Usuda, J. and Saijo, N.: Mitogenactivated protein kinase antisense oligonucleotide inhibits the growth of human lung cancer cells. Int. J.
of Oncology, 14, 461-469, 1999
35. Okunaka, T., Hiyoshi, T., Furukawa, K., Yamamoto, H., Tsuchida, T., Usuda, J., Kumasaka, H.,
Ishida, J., Konaka, C and Kato, H.: Lung cancers treated with photodynamic therapy and surgery.
Diagnostic and Therapeutic Endoscopy, 5, 155-160, 1999
36. Furukawa, K., Okunaka, T., Yamamoto, H., Tsuchida, T., Usuda, J., Kumasaka, H., Ishida, J.,
Konaka, C. and Kato, H.: Effectiveness of photodynamic therapy and Nd-YAG laser treatment for
obstructed tracheobronchial malignancies. Diagnostic and Therapeutic Endoscopy, 5, 161-166, 1999
37. Tomonari, A., Nishio, K., Kurokawa, H., Fukumoto, H., Fukuoka, K., Iwamoto, Y., Usuda, J.,
Itakura, M. and Saijo, N.: Proximal 5-flanking sequence of human gamma-glutamylcystein synthetase
heavy subunit genes is involved in cisplatin-induced transcriptional up-regulation in a lung cancer cell
line SBC-3. Biochemical Biophysics Research Communication, 236, 616-621, 1997
38. Miura, H., Taira, O., Uchida, O., Usuda, J., Hirai, S. and Kato, H.: Spontaneous haemothorax
associated with von Recklinghausen's disease. Thorax, 52, 575-578, 1997
39. Miura, H., Kato, H., Konaka, C., Usuda, J., Uchida, O. and Taira, O.: Primary lung cancer of the
middle lobe. Is its prognosis poor? Lung Cancer, 14, 273-279, 1996
Societies:
International Association for the Study of Lung Cancer
International Photodynamic Association
American Association for Cancer Research
American Society of Clinical Oncology
American Society for Photobiology
Japanese Cancer Association
Japan Society of Clinical Oncology
Japan Surgical Society
Japan Surgical Association
Japan Society for Laser Medicine
Japanese Association for Thoracic Surgery
Japanese Association for Chest Surgery
Japan Society for Bronchology
Japan Lung Cancer Society
Japan Broncho-Esophagological Society
Wilson, Brian
Professor Ph.D., Glasgow Ontario Cancer Institute / Princess Margaret Hospital 610 University Avenue, Room 7-­‐417 Toronto, ON M5G 2M9 CANADA Email: [email protected] The focus of the research of the Laser Biophysics group is the development and application of new
therapeutic and diagnostic techniques based on the use of lasers and other optical technologies. In this
translational research, a wide range of methodolo- gies are used: theoretical and experimental studies
of light transport in tissues, development of light sources/optical-fiber light delivery devices and of
optical dosimeters, photobiological studies at the cellular and tissue level, in vivo optical spectroscopy
of tissues, development of prototype clinical instruments, and co-operative clinical trials.
Two examples will serve to illustrate the work: the first therapeutic and the second diagnostic.
Photodynamic therapy (PDT), the use of light-activated drugs (photosensitizers), is being developed as
a new method for selective destruction of solid tumours. We are currently using an animal model to
study the relationships between tissue response and the light and photosensitizer 'doses'. A particular
focus at present is on malignant brain tumours. This involves induction of intracranial tumours in an
animal model, PDT treatment via interstitially-placed optical fibers with simultaneous measurement of
light fluences in situ, followed by quantitative histopathology and biochemical analysis of resected
tissues. These data are then combined in a model of the photodynamic process to determine the
fundamental PDT sensitivity of the tissue-photosensitizer combination. We have recently found that
one photosensitizer (5d-aminolevulinic acid, a heme precursor) has an extremely high sensitivity in
tumour compared to normal white matter in the brain. This will lead to a Phase I clinical trial of this
drug.
Wolfsen, C. Herbert(MD)
Division Of Gastroenterology And Hepatology
Mayo Clinic
4500 San Pablo Road
Jacksonville
FL 32224
Email: [email protected]
Education:
Internal medicine at Virginia Mason Medical Center (Seattle, Washington, USA) with Dr Richard A.
Kozarek; GI Fellowship 1990-93 at Mayo Clinic, Rochester, Minnesota, USA with Dr. Kenneth K.
Wang; Mayo Clinic, Jacksonville Florida USA staff member as Consultant, Division of
Gastroenterology and Hepatology since 1995 and Associate Professor of Medicine, Mayo Clinic
College of Medicine, Rochester, Minnesota USA.
Biography:
CAREER HIGHLIGHTS:
Developed Mayo Clinic Jacksonville Endoscopic Ablation Program for patients with Barrett's
Dysplasia and Early Esophageal Carcinoma (1997) that now includes Advanced Endoscopic Imaging
for dysplasia detection including use of high definition endoscopy, narrow band imaging, autofluorescence imaging.
Program has led to advancement in Professional Society and in Research opportunities
o Founder and Chair of the ASGE Special Interest Group "Endoscopic Therapy for Esophageal Disease
(ETED)"
o Leadership position within the ASGE and DDW participant since 2004
o Participant in AGA "Advanced Clinical Imaging" section with DDW participation since 2005
o Outstanding Faculty Member Award - School of Continuing Medical Education, Mayo Clinic
College of Medicine, 2006
RESEARCH GRANTS AWARDED
Principal Investigator Supplement from the GI SPORE at the University of Arizona Cancer Center.
04/2006 - 07/2007
Principal Investigator Randomized Double-Blind Phase II Trial of Esomeprazole versus Esomeprazole
+ Two Doses of Aspirin in Barrett's Esophagus Patients. 09/2006 - 08/2008
Principal Investigator Ablation of Intestinal Metaplasia containing Dysplasia (AIM Dysplasia Trial) A
Multi-Center, Randomized, Controlled Trial. 05/2006 - 05/2010
Principal Investigator Controlled Endoscopic Study of Tri-Modal Imaging for the Detection of High
Grade Dysplasia in Barrett's Esophagus. 08/2007 - 08/2008
Principal Investigator Narrow Band Imaging (NBI) Directed Biopsies for Detection of Dysplasia in
Patients with Barrett's Esophagus. 07/2005 - 06/2007
Principal Investigator In Vivo Fluorescence and Light Dosimetry Modeling for Esophageal
Photodynamic Therapy. Funded by Mayo Discretionary Funds (collaboration with Dr Linda Jones,
Biophysics Department, College of Charleston) 03/2006 - 03/2007
Principal Investigator Endoscopic Tri-Modal Imaging for the Detection of High Grade Dysplasia and
Early Cancer in Barrett's Esophagus: A Feasibility Study. 05/2006 - 05/2007
SELECTED RECENT PUBLICATIONS
Wolfsen HC. Present status of photodynamic therapy for high-grade dysplasia in Barrett's esophagus. J
Clin Gastroenterol 2005 Mar; 39(3):189-202.
Wolfsen HC. Uses of photodynamic therapy in premalignant and malignant lesions of the
gastrointestinal tract beyond the esophagus. J Clin Gastroenterol 2005 Sep; 39(8):653-64.
Wolfsen HC. Endoprevention of esophageal cancer: endoscopic ablation of Barrett's metaplasia and
dysplasia. Expert Rev Med Devices 2005 Nov; 2(6):713-23.
Shah AK, Wolfsen HC, Hemminger LL, Shah AA, DeVault KR. Changes in esophageal motility after
porfimer sodium photodynamic therapy for Barrett's dysplasia and mucosal carcinoma. Dis Esophagus
2006; 19(5):335-9.
Wolfsen HC, Hemminger LL. Salvage photodynamic therapy for persistent esophageal cancer after
chemoradiation therapy. Photodiagnosis & Photodynamic Therapy 2006 Mar; 3(1):11-4.
Ward EM, Wolfsen HC, Achem SR, Loeb DS, Krishna M, Mitchell KM, Hemminger LL, DeVault
KR. Barrett's esophagus is common in older men and women undergoing screening colonoscopy
regardless of reflux symptoms. Am J Gastroenterol 2006 Jan; 101(1):12-7.
Wolfsen HC. Salvage photodynamic therapy by using porfimer sodium after chemoradiation therapy: a
Western viewpoint. Gastrointest Endosc 2006 Jan; 63(1):195.
Wolfsen HC, Canto M, Etemad B, Greenwald B, Gress F, Schembre D, Muthusamy V, Ribiero A,
Sharma V, Ginsberg G. Bare Fiber Photodynamic Therapy Using Porfimer Sodium for Esophageal
Disease. Photodiagnosis and Photodynamic Therapy 2006, May(3):87-92.
Wolfsen HC. Endoluminal therapy for Barrett's esophagus. Gastrointest Endosc Clin N Am 2007 Jan;
17(1):59-82, vi-vii.
General Members
The following is a simple alphabetical list of current IPA members.
We plan in time to provide more information on each of our members and would appreciate it if all
members listed here could e-mail a short biography and digital photograph to
[email protected] for inclusion. For details of how to become a member of the IPA please
click here
Name
Mr Stephen
Adcock
Dr Ernest
Allan
Dr James
Allen
Ron Allison,
M.D.,
Prof Alex
Anstey
Mr. Tsunenori
Arai
Prof Luis
Arnaut
Dr Philippe
Arnoux
Professor
Vanderlei S.
Bagnato
Prof Hugh
Barr
Prof. J. Patrick
Barron
Address
Dept of Oral & Maxillofacial Surgery Royal Cornwall Hospitals MHS Trust Treliske
Truro TR4 8RW UK
22 Heath Drive Knutsford Cheshire WA16 0WS UK
Clinical Photobiology, ECEHH, Peninsula Medical School, Knowledge Spa, Royal
Cornwall Hospital, Truro, Cornwall, TR1 3HD, UK
21st Century Oncology, 801 W H Smith Boulevard Greenville, North Carolina 27858
U.S.A.
Academic Dermatology Royal Gwent Hospital Cardiff Road Newport NP20 2VB Wales
3-14-1, Hiyoshi, Kohoku-ku Yokohomashi, Kanagawa Japan
Luzitin, S.A., Edificio Bluepharma, Sao Martinho do Bispo, 3045-016 Coimbra - Portugal
Laboratoire Réactions et Génie des Procédés (LRGP), Nancy Université, 1 rue Grandville
BP20451 Cedex (FRANCE)
Av Do Trabalhador Sao Carlense, 400, Sao Carlos-SP-Brazil, CEP 13566-590
Ward 5A Office Gloucestershire Royal Hospital Great Western Road Gloucester GL1
3NN UK
International Medical Communications Center Tokyo Medical University 6-7-1
Nishishinjuku, Shinjuku-ku Tokyo 160-0023 Japan
David A
Bellnier, Ph.D.
Prof Kristian
Berg
Merrill A.
Biel, M.D.,
Ph.D.
Dr. Robert
Bissonnette
Prof Nicola
Jane Brown
Dr. Cale
Dr Sandra
Campbell
Dr Carlos
Austerlitz
Campos
Dr Chin-Tin
Chen
Dr Bin Chen
Mr Gary
Conroy
Seid Cosovic,
MD
Dr W Thomas
John Crawford
Dr W Thomas
John Crawford
Mrs Carolyn
Cross
Dr. Alison
Curnow
Tom Dawson
Dr Elodie
Debefve
Mr Michael
George Dilkes
Dr Ryan F
Donnelly
Dr. Richard B
Dorshow
Thomas J.
Dougherty,
Ph.D.
Mr Kevin
Duffy
Dept. of Cell Stress Biology, Roswell Park Cancer Institute Elm & Carlton Streets
Buffalo, New York 14263 USA
The Norwegian Radium Hospital University Hospital Montebello 0310 Oslo Norway
Advanced Photodynamic Technologies, Inc. 2715 4th Street, SE Suite 70 Minneapolis,
MN 55414 USA
Innovaderm Research Inc 1851 Sherbrooke East Suite 502 Montreal Quebec H2K 4L5
Canada
Microcirculation Research Group Academic Unit of Surgical Oncology Floor K School of
Medicine & Biomedical Sciences University of Sheffield Sheffield S10 2RX UK
19017 - 120th Avenue NE, Bothell, WA 98011, USA
Dermatology Department Royal Cornwall Hospital Treliske Truro Cornwall TR1 3LJ UK
802 Treybrooke Circle, Apartment 14, Greenville, North Carolina, USA
Department of Biochemical Science & Technology National Taiwan University No1, Sec
4 Roosevelt Road Taipei 10617 Taiwan
Department of Pharmaceutical Sciences, University of the Sciences in Philadelphia, 600
South 43rd Street, Philadelphia, Pennsylvania 19104, U.S.A.
39 Quakers Hall Lane Sevenoaks Kent TN13 3TX UK
888 W Big Beaver Road Suite 309 Troy MI 48084 USA
Appearance Medical Clinic PO Box 2349 Bendigo DC Victoria 3554 Australia
Appearance Medical Clinic, PO Box 2349, Bendigo, DC, Victoria 3554, Australia
Ondine Biomedical Inc., 88-1100 Melville Street, Vancouver, BC V6E 4A6, Canada
Clinical Photobiology, ECEHH, Peninsula Medical School, Knowledge Spa Royal
Cornwall Hospital Truro TR1 3HD United Kingdom
EPFL, Medical Photonics Group, Station 6, CH-1015 Lausanne, Swtizerland
The London Laser Clinic 3 Dronken House 43A High Street Kings Langley WD4 8FG
UK
Senior Lecturer in Pharmaceutics School of Pharmacy Queen’s University Belfast
Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK
Director R&D, Covidien Pharmaceuticals, 675 McDonnell Boulevard, Hazelwood, MO
63042, USA
Professor of Oncology, Roswell Park Cancer Institute Elm & Carlton Streets Buffalo,
New York 14263-0001 U.S.A.
Galderma (UK) Ltd Meridien House 69-71 Clarendon Road Watford WD17 1DS UK
Department of Neurosurgery, Ninewells Hospital & Medical School, Dundee, DD1 9SY,
Professor Sam United Kingdom
Eljamel
www.neurosurgery-mse.com
Prof Mark
London Urology Associates 114a Harley Street London W1G 7EL UK
Emberton
Dr Kathleen
Fan
Mr. Richard P.
Felten
Dr. Peter
Fergin,
Prof. Thomas
H. Foster
Mr Darren
Freeman
Kinya
Furukawa,
M.D., Ph.D.
A-F
King’s College Hospital Department of Maxillofacial Surgery Bessemer Road
London SE5 9RS UK
Food and Drug Administration, 10903 New Hampshire Avenue, Silver Springs, MD
20993-0002, USA
110 David Street Dandenong, Victoria 3175 Australia
University of Rochester, Department of Imaging Sciences, 601 Elmwood Avenue, Box
648, Rochester, New York 14642, USA
http://www.urmc.rochester.edu/radiology/research/foster/index.cfm
Dept. of Thoracic Surgery Tokyo Medical University, Kasumigaura Hospital 3-20-1
Chuou, Ami-machi, Inashiki-gun Ibaraki 300-0395 Japan
Name
Michael H. Gold,
M.D,
Dr. Charles
Gomer,
G-M
N-S
Address
Gold Skin Care Center, Tennessee Clinical Research, 2000 Richard Jones Road,
Suite 220, Nashville, Tennessee 37215, USA
Childrens Hospital Los Angeles, University of Southern California, MS# 67 Los
Angeles, California 90027 U.S.A.
Professor and Chair, Radiation Oncology, Hospital of the University of
Professor Stephen
Pennsylvania, 2 Donner, 3400 Spruce Street, Philadelphia, Pennsylvania 19104,
M. Hahn
U.S.A.
Prof. Tayyaba
Massachusetts General Hospital, Wellman Lab. of Photomedicine 40 Blossom
Hasan, PhD
Street, Boston, Massachusetts 02114 U.S.A.
Barbara W.
Photodynamic Therapy Center, Roswell Park Cancer Institute Elm & Carlton
Henderson, Ph.D. Streets Buffalo, New York 14263 U.S.A.
Prof Dr Peter
Hannover School of Medicine Department of Obstetrics & Gynecology CarlHillemans
Neuberg-Str 1 D-30625 Hannover Germany
Theodor A.
Masaryk University Medical School, Faculty Hospital Bohunice Department of
Horvath, M.D,
Surgery Jihlavska 20, CZ-625 00 Brno Czech Republic
PhD,
32023 Dept of Bioscience Technology, Chung-Pei Road, Chungli, Taoyuan,
Prof Yih-Chih Hsu
Taiwan, ROC
Dr Sally H
Photobiology Unit Dermatology Department Ninewells Hospital Dundee DD1 9SY
Ibbotson
UK
Prof. David A.
c/o Dept for Biochemistry and Molecular Biology, Monash University Building 77,
Jans
Room 146, Monash, Victoria 3800, Australia
Prof Dr Med
Direktor Linik u PoliKlinik fur Urologie, Universitatskinikum Schleswig-Holstein,
Dieter Jocham,
Ratzeburger Allee 160 23538 Lubeck, Germany
M.D.
Kevin Jordan,
London Regional Cancer Program, Physics & Engineering Dept. 790
Ph.D.
Commissioners Road East London Ontario N6A 4L6 Canada
Dr Asta Juzeniene, Department of Radiation Biology, Institute for Cancer Research, Norwegian
Ph.D.
Radium Hospital, Oslo University Hospital, Montebello, Oslo, Norway
Dr Stephen C
Center for Optical Diagnostics and Therapy, Dept of Radiation Oncology, Erasmus
Kanick
Medical Center, Dr Molewaterplein, Room Ee1683, 3015 GE, Rotterdam
Prof Norimichi
1614 Kurogane-cho Aoba-ku Yokohama 225-8502 Japan
Kawashima
James Stewart Professor of Surgery, Head, Department of Surgery, The University
Prof. Andrew H.
of Melbourne, Department of Neurosurgery, The Royal Melbourne Hospital,
Kaye,
Grattan, Parkville, Victoria 3050 Australia
Dr Steve Keohane Portsmouth Dermatology Centre St Mary’s Hospital Milton Road Portsmouth
T-Z
Prof. David
Kessel,
Dr Akbar Khan
PO3 64D UK
Pharmacology, Wayne State University School of Medicine 540 East Canfield
Street Detroit, Michigan 40201 U.S.A.
Medicor Cancer Centres, Suite 412, 4576 Yonge Street, Toronto, Ontario, M2N6N4, Canada
Pres Prof Jin
Kang Nam Gu Sin Sa Dong 638-5, Best Well Institute, Dept. of Plastic Surgery,
Wang Kim, M.D.,
Zip 135-896, Seoul South Korea
Ph.D.
British Columbia Cancer Agency, British Columbia Cancer Research Centre 675
Dr Mladen
West 10th Avenue Vancouver, British Columbia, V5Z 1L3 Canada
Korbelik
www.bccrc.ca
Prof. Dr. Herwig
Facharzt f. Neurochirurgie, Colingasse 5 6020 Innsbruck Austria
Kostron,
Number 113, 6th Floor, 675 West 10 Avenue Vancouver British Columbia V5Z
Dr Stephen Lam,
1L3 Canada
Dr John Lear
Dermatology Centre Hope Hospital Salford Manchester M6 8HD UK
Dr John Lear
Dermatology Centre Hope Hospital Salford Manchester M6 8HD UK
Dae-Hee Lee,
613-8 Anyang 5-dong, Mana-gu, Anyang-si, Gyeonggi-do, 430-733, South Korea
Nick Loebel
Dr Harvey Lui,
3rd Floor - 835 West 10th Avenue Vancouver, British Columbia, V5Z 4E8 Canada
Dr Alexander J
University College London Charles Bell House 67 – 73 Riding House Street
MacRobert
London W1W 7EJ UK
Prof. Zvi Malik
Life Sciences Faculty, Bar Ilan University, Ramat Gan 52900, Israel
Dermatology & Biomedical Engineering, Mailstop ND-20, Lerner Research
Edward V Maytin
Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 4122, USA
MD PhD
http://www.lerner.ccf.org/bme/maytin/
Prof Norio
Department of Tumor Pathology, Faculty of Medicine, National University of
Miyoshi
Fukui, #23-3, Matsuoka, Eiheiji-cho, Yoshida-gun Fukui-Pref, 910-1193 Japan
Prof Keyvan
The Yorkshire Laser Centre Goole & District Hospital Woodland Avenue Goole
Moghissi
East Yorkshire DN14 6RX UK
Dr Colin Morton
Prof Harry
The Photobiology Unit, Ninewells Hospital & Medical School, Dundee, DD1 9SY
Moseley
Ross M Taylor,
Interventional Endoscopy & Nutritional Support Cancer Treatment Centers of
MD
America 1010Q E 79th Street Tulsa Oklahoma 74133 USA
Prof. Paul J.
Muller, M.D.,
2 Queen Street East, Suite 1005, Toronto, Ontario, M5C 3G7 Canada
F.R.C.S.(c)
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Nobue Nakajima
Dr Yow Li Miu
Ngan
Prof. Nancy L.
Oleinick,
1614 Kurogane-cho Aoba-ku Yokohama 225-8502 Japan
Rm Y930 Medical Laboratory Sciences Department of Health Technology &
Informatics Hong Kong Polytechnic U HKSAR
Department of Radiation Oncology, School of Medicine (BRB-324) Case Western
Reserve University 10900 Euclid Avenue Cleveland, Ohio 44106-4942 U.S.A.
Division of Obstetrics & Gynecology College of Medicine Dankook University
Professor ChoongSan-29 Anseo-Dong Dong Nam Gu, Cheonan Chungcheong Nam Do, 330-714,
Hak Park
Republic of Korea
Dr Stephen P
University Department of Surgery 9th Floor Royal Free Hospital Pond Street
Pereira
London NW3 2QG UK
John Pickering
Brian W. Pogue
PhD,
Dr Raghavan
Rajagopalan
Dr. Dominic J.
Robinson
Ross M Taylor,
MD
Ross M Taylor,
MD
Mr Colin
Sherwood
Dr. Kallis Sideri
Univ-Prof Dr
Alexis Sidoroff
Frank I Singleton
Jr, MD
Dr. Charles W.
Spangler,
Prof H J C M
Sterenborg
Grove Park House 85 Claremont Road Tunbridge Wells TN1 1TE
Thayer School of Engineering, Dartmouth College 8000 HB, Cummings Hall
Hanover, NH 03755 USA
Covidien Pharmaceuticals, 675 McDonnell Blvd, Bldg 20-2-W, Hazelwood, MO
63042, USA
Center for Optical Diagnostics & Therapy, Department of Radiation Oncology,
Erasmus Medical Center, Dr Molewaterplein, Room Ee1675, 3015 GE Rotterdam
The Netherlands
Interventional Endoscopy & Nutritional Support Cancer Treatment Centers of
America 1010Q E 79th Street Tulsa Oklahoma 74133 USA
Interventional Endoscopy & Nutritional Support Cancer Treatment Centers of
America 1010Q E 79th Street Tulsa Oklahoma 74133 USA
40 Lynmouth Drive Minster on Sea Isle of Sheppey Kent ME12 2HT
37a, Great Cumberland Place, Flat 3C, Marble Arch, London, W1H 7TD, UK
Medical University of Innsbruck Dept of Dermatology Anichstrasse 35 A6020
Innsbruck Austria
36 Island Avenue #22 Miami Beach Florida 33139 USA
SensoPath Technologies, Inc, 920 Technology Blvd, Suite B, Bozeman, MT
59718, USA
Center for Optical Diagnostics & Therapy, Erasmus Medical Centre, POB 2040,
NL-300 CA, Rotterdam, Netherlands
Copyright © 2005 - 2013 IPA
A-F
Name
Dr Jitsuo Usuda MD,
PhD
Kenneth Wang, M.D.
Max J H Witjes, MD,
DDS, PhD,
Dr Xuguang Zheng
Prof. Emeritus Takato
O. Yoshida
Dr Baozhong Zhao
Dr Lei Zak Zheng
G-M
N-S
T-Z
Address
6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan
Mayo Clinic 200 First Street, SW, Alfred M430 Rochester, MN 55905, USA
Dept Oral & Maxillofacial Surgery, University Medical Center, P.O. Box
30.001, 9700 RB Groningen, The Netherlands
1950 Golfview Drive, Apartment 121, Troy, Michigan 48202, USA
4-607, 2-19 Edahigashi, Tsuduki-ku, Yokohama, Kanagawa 224-0006, Japan
5011 S Alston Ave Apt #A206, Durham, NC 27713, USA
Wellman Centre for Photomedicine, 40 Blossom Street, Boston,
Massachusetts, 02114, USA
Copyright © 2005 - 2013 IPA