Buyers Guide - American Academy of Anti
Transcription
Buyers Guide - American Academy of Anti
Buyers Guide DIRECTORY ◗ Product Announcements 154 Vendors by Category ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ ◗ Aesthetic Medical Treatments 166 Alternative Therapies 166 Compounding Pharmacies 168 Computer / EMR 169 Cosmeceuticals 169 Dermatology 169 Diagnostic Service / Laboratories 170 Hair Rejuvenation 172 Holistic Medicines 172 Hyperbaric / Oxygen Therapies 172 Insurance / Finance Practice Management / Marketing 172 Med Spa / Equipment 172 Medical Equipment / Supplies 174 Medical Publications / Directories 174 Mesotherapy / Hormone Therapies 176 Miscellaneous 176 Nutraceuticals 178 Pharmaceutical 180 Sports / Fitness / Physical Therapies 180 Stem Cell Therapies 181 Weight Management 181 Arasys offers effortless inch loss and cellulite reduction. It was built in London University by the co-inventor of the rst Pacemaker. High resonance, analogue, multi-frequency waveform tailors itself to individual resistance, being impossible to duplicate. Arasys is used in Dutch and Russian hospitals as well as by international doctors to treat Multiple Sclerosis & Neurological Defects. It is also used internationally to heal chronic and acute pain. Plastic Surgeons use it to rm loose skin after liposuction. Gynecologists use it to tighten the loose abdomen muscles after pregnancy. PRODUCT Announcements ◗ clinical benefits of Photopneumatic™ Profusion combines the proven clinical benefits of Photopneumatic™ (Photo=light and Pneumatic=vacuum) light treatments with the delivery of Aesthera’s proprietary therapeutic skincare to symbiotically enhance the outcomes for skin rejuvenation and acne treatments. Profusion Skin Therapy: • Overcomes challenges of topical application • A novel 15-minute painless treatment • Only available on the Isolaz Pro • Safe and effective on all skin types Two step process: 1. Aesthera’s Photopneumatic treatments mechanically cleanse the sebaceous gland and treat the target with light 2. Profusion applicator delivers proprietary therapeutic materials into the skin. Aesthera 6634 Owens Dr. Pleasanton, CA 94588 877-275-4779 [email protected] www.AESTHERA.com ◗ Daiwa Health Development Launches Plasmanex1™ for Optimum Blood Circulation Plasmanex1™, a dietary supplement with the active ingredient Bacillopeptidase F Proprietary Blend (BFPB), a natural soy enzyme extracted by using a patented fermentation production process and shown to support healthy blood circulation, has been introduced to the health practitioner marketplace by Los Angeles-based Daiwa Health Development. Plasmanex1™ has three primary functions, confirmed through several studies, including balancing blood flow through PAI-1 and t-PA, retarding thrombosis in abnormal coagulation states and decreasing blood viscosity through reduction of fibrinogen. The actions of preventing thrombus formation and decreasing blood viscosity make Plasmanex1™ unique. In some studies on patients with acute coagulation changes, the use of Plasmanex1™ caused an increase in t-PA activity, an enzyme which acts to rapidly break down newly formed blood clots in the blood vessels, and promotes plasmin viability. This activity led to increased t-PA levels, ultimately increasing clot dissolution activity. Plasmanex1™ restored the PAI-1/t-PA balance and lowered overall clot levels of fibrin and fibrin degradation products. For complete Plasmanex1™ study information and in-office health practitioner product sales, contact Daiwa Health Development at 877.434.3633 or by email at [email protected]. ◗ Frequency Specific Microcurrent Anti-Aging Module – FSM A2 M This easy to use module combines proven frequency specific anti-aging effects with the benefits of microcurrent. Frequency Specific Microcurrent (FSM) has transformed pain management for over a thousand practitioners in every medical discipline on three continents during the last 12 years. Now for the first time FSM brings the benefits of microcurrent and frequency specific effects to Anti-Aging physicians and their patients. Microcurrent increased ATP production by 500% in rat skin, increased collagen by 14% and elastin by 48% in rabbits. Only two specific frequencies reduced lipoxygenase mediated inflammation by 62% in four minutes in mice. Only two specific frequencies reduced inflammatory cytokines by ten to twenty times in 90 minutes when no other frequency had any effect. The FSM A2 M contains more than twenty Frequency Specific Microcurrent preprogrammed protocols customized for the anti-aging physician to be used in the office or sold to patients for home use. Special introductory price $2495! Contact Precision Distributing 1-800-218-3401 154 ❘ ANTI-AGING MEDICAL NEWS SPRING 2009 PRODUCT Announcements ◗ EstrogenDetox-FASTER Estrogen Metabolism and Excretion! Excess Estrogen in Women can cause breast cysts, Ovarian Cysts, Uterine Cysts, Endometriosis, Excess Bleeding at Menstrual Time, PMS. Excess Estrogen in Men can cause benign Prostate Hypertrophy, Prostate Cancer, Prostate Pain, Decreased Libido, Gynecomastia, Weight Gain, & Feminization. EstrogenDetox can Help! • Protects Estrogen Receptors from the Circulating Estrogen • Diminish the half-life time of the Estrogen Circulating in our body. • Lowers the Level of Beta-Glucoronidase, which Lowers the Risks of Various Cancers of the Breast, Skin, Liver, Lung, Prostate, Colon. • Greater Secretion of the Estrogen and Metabolized much Quicker. • Stop Losing Testosterone to Aromatase EstrogenDextox has a A Special Natural Extraction Process including Sarasparilla S. Officinalis, Chinensis, Araliacea, Zingiberoide Curcuma, Purple Nutsedge C. Rotundus, Calcium D-glucorate. Health Secrets USA 24141 Ann Arbor Trail, Dearborn Heights, Michigan 48127 Tel: (313) 561-6800 Fax: (313) 561-6830 E-mail: [email protected] ◗ Very Effective and Successful New Product, Nutra Fill/ NMF Booster CosMedical Technologies, Inc. has just launched a very effective and successful new product, Nutra Fill/ NMF Booster. This product is uniquely positioned as a “topical filler” that acts by lessening the appearance of lines and wrinkles via short contact therapy. It features components of the epidermal Natural Moisturizing Factor (NMF) responsible for keeping youthful skin surface plumped and smooth. The Company’s Chief Medical Officer and formulator, Loretta Ciraldo, M.D., F.A.A.D., has developed a great educational newsletter for distribution with this product. Write to [email protected] or call 1-800-275-3627 for more information or to order product. ◗ New Product Youth Juice Youth Juice currently yields the highest ORAC value of any product on the market (12,350 per serving). In the world of anti-aging medicine highest ORAC translates to highest anti-aging effects. Anti-aging physicians classify Youth Juice as the top anti-aging functional food product currently available. Youth Juice is a drink made of 100% pure organic berries and sea vegetables. It is the perfect mixture of land and sea as it contains seven important antioxidant-loaded and 7 cancer-fighting berries as well as 3 immune-enhancing and detoxifying sea vegetables (fucoidan, rockweed, and ulva). Youth Juice was developed in cooperation with a Canadian Government Research and Development Grant. Stop by the University Compounding Booth #503 for a free sample and more information. Youth Juice 1875 3rd Ave. San Diego, CA 92101 Phone: 619-683-2005 Web site: www.ucprx.com SPRING 2009 ANTI-AGING MEDICAL NEWS ❘ 155 PRODUCT Announcements ◗ Introducing Enagic’s line of Water Ionizers! Enagic sets the Gold Standard for water ionizers. Our water ionizers have won numerous awards and certifications, including the Linus Pauling Award. Enjoy the benefits of Kangen Water™ for its healing & anti-aging properties, anti-oxidants, micro-clustering and alkalization. Approved by Japan’s FDA, this water is used more than any other treatment or medication and is used by 95% of the hospitals in Japan. It is used to cure atopic dermatitis, psoriasis, gangrene and acne. It is also used for treatment of adult diseases; diabetes, high cholesterol, acid reflux, high blood pressure, fibromyalgia and cancer. The Kangen machine uses 230 watts to power water over the 7 solid electrolysis plates making stronger, longer lasting hexagonal water over our closest competitor. No other ionizer makes the 2.5 or 11.5 strong waters. For more information, please contact: You’re Kangen Water Team @ (206) 406-8720 [email protected] www.thewatertruth.com/returntoorigin ◗ Integra-Lean™ Irvingia from Life Extension® Integra-LeanTM Irvingia, a proprietary plant extract, circumvents four molecular factors that lead to age-related weight gain.* • It reverses resistance to leptin, the hormone that signals the brain to turn off the appetite and break down stored fat.1 • It increases secretion of adiponectin, a hormone that supports insulin sensitivity and cardiovascular health.1 • It inhibits the enzyme that converts sugar to fat.1 • And inhibits the digestive enzyme that allows starches to be absorbed as sugar.1 In the largest human study to date, people taking it lost 28 pounds in 10 weeks.2,3 Contact us on how to become a reseller to increase your practice revenues. 1. Lipids Health Dis. 2008 Nov 13;7:44. 2. Submitted for publication, 2008. 3. 5th International Conference on Functional Foods for Chronic Diseases: Obesity & Related Diseases. Presented 2008 Oct 17. www.LifeExtensionRetail.com 1-888-884-3657 ◗ Slimming Fat Burn Liposome Cream Scientifically Backed Active Ingredient 7-Keto * 300% more Weight Loss than Diet and Exercise Alone * Majority of Weight Loss is Fat Loss * Promotes Weight Loss without Use of Stimulants * Active Ingredient Awarded a Patent for Weight Loss * Increase Metabolism without the Use of Stimulants 1. Slimming Fat Burn (7-Keto) liposome transdermal topical cream may help you lose inches! 2. 7-Keto is a naturally occurring substance produced by the body in the adrenal glands and its production declines with age. 3. It is a non-stimulant, thermogenic agent that is clinically proven to increase metabolism and promote healthy weight loss. * Apply Directly to the Fat Area of Your Body! Health Secrets USA 24141 Ann Arbor Trail, Dearborn Heights, Michigan 48127 Tel: (313) 561-6800 Fax: (313) 561-6830 E-mail: [email protected] 156 ❘ ANTI-AGING MEDICAL NEWS SPRING 2009 Delicate Touch. Dramatic Results. CALL NOW Introducing the first peel system in the industry with epidermal growth factors. Realize luminous results with less irritation than traditional retinol peels with the Bene-factor Peel and Factor Infusion Kit. Contact Results Rx today for more information on these and other innovative products in our physician-only collection. resultsrx.com • 1.877.367.7975 PRODUCT Announcements ◗ New Oral Glutathione (GSH) Nearly 100% Bioavailable Real GSH – not a precursor or secretagogue – is now available in liposomal form. Research suggests liposomal delivery of nutrients is even superior to IV infusion since they can carry their intact payload through the digestive system, into the bloodstream and across cell membranes. Nearly 80,000 studies document the anti-aging, anti-oxidant, detoxifying, and protective qualities of GSH. Now GSH can be delivered directly into the cellular cytoplasm with Lypo-Spheric™ GSH, the only unidose glutathione using Liposomal Encapsulation Technology. Lypo-Spheric™ GSH is available for resale from LivOn Labs at www.livonlabs.com or by calling 1-866-682-6193. ◗ The Fat-Soluble Vitamins Profile from Metametrix Clinical Laboratory Fat-Soluble VITAMINS The Fat-Soluble Vitamins Profile from Metametrix Clinical Laboratory is a great tool to gain an overall perspective of a patient’s health, nutrient processing, and dietary insufficiencies. Serum levels of the fat-soluble vitamins A, D, E, K plus beta-carotene and coenzyme Q10 are measured to evaluate total body status of these antioxidant nutrients. Testing these nutrients together in one panel is important because nutrient functionality is dependent on the adequate supply of each nutrient. Some symptoms of vitamin insufficiency include impaired immune function, reoccurring infections, neurological disease, heart disease, osteopenia and osteoporosis, chronic fatigue, increased oxidative stress, poor dietary intake and impaired digestion and absorptions. Order a Fat-Soluble Vitamins Profile today by calling 1-800-221-4640 or visit www.metametrix.com. SM Metametrix Clinical Laboratory 3425 Corporate Way Duluth, GA 30096 770-446-5483 800-221-4640 Fax: 770-441-2237 Web site: www.metametrix.com ◗ Nordic Naturals ProOmega LDL Based upon clinical research, Nordic Naturals ProOmega LDL combines the cardiovascular benefits of concentrated omega-3 fish oil with the lipid-metabolizing action of red yeast rice and the additional support of CoQ10. This synergistic formula supports normal blood lipid levels in healthy individuals, promotes healthy endothelial function, and enhances overall cardiovascular health.* As with all Nordic Naturals products, ProOmega LDL delivers EPA and DHA in the natural triglyceride form and industry-leading purity and freshness, resulting in improved compliance and thus superior patient outcomes. Each serving provides 390 mg EPA, 270 mg DHA, 800 mg red yeast rice powder, and 60 mg CoQ10. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Nordic Naturals 94 Hanger Way Watsonville, CA 95076 Phone: 831-724-6200 Fax: 831-763-9329 Web site: www.nordicanaturals.com 158 ❘ ANTI-AGING MEDICAL NEWS SPRING 2009 PRODUCT Announcements ◗ A New Foundation for Your Anti-Aging Practice SpectraCell Laboratories is excited to announce the development of a high throughput cellular aging (telomere) test based on real time PCR technologies. Telomeres act as molecular clocks in cells, and shorten each cell division. Shortened telomeres may be responsible for some of the changes associated with normal aging and are associated with sedentary lifestyles and chronic inflammation, vitamin D deficiency, osteoarthritis and increased mortality from cardiovascular disease and infections. It is the goal of SpectraCell Laboratories to continue to help people make better informed health decisions through advanced diagnostic testing. Telomere testing will be available at SpectraCell in Spring 2009. For more information, please contact SpectraCell Laboratories at 800-227-LABS. ◗ SR-T2 Px: Thyroid hormone metabolite supplement you can use without a prescription Many patients have low body temperatures and symptoms consistent with slow metabolisms, even though their blood tests are normal. T2 is a close metabolite of the thyroid hormones T4 and T3 that has long been considered inactive. Yet, T2 has been shown to increase metabolic rate and thermogenesis! It is usually very well tolerated and can be helpful in increasing low body temperature as is seen in Wilson’s Temperature Syndrome. T2 has also shown minimal effects on TSH levels. It can also be used along with T3 or T4. T2 has been shown to be less cardio-active than T3. However, caution still needs to be used since it potentially can cause heart palpitations. The formula contains a sustained release agent thereby preventing a sudden surge of T2 in the bloodstream. WTSmed, Inc. Phone: 800-420-5801 Web site: www.wtsmed.com E-mail: [email protected] ◗ Direct more patients to your website with FlexPPC In this economy, forget TV. Forget phone books. Forget radio. Marketing should be measurable and generate results. Go where your patients are looking for you: Online. How are patients finding your practice online? Stop guessing and start being proactive. Direct more patients to your website with FlexPPC, an innovative pay-per-click marketing tool that drives more of the right traffic to your website. FlexPPC puts your website on all of the major search engines - Google, Yahoo, and MSN. Then it maximizes exposure by purchasing keywords that are known to generate the most traffic to your site and give you potential leads. For further info please visit www.locateadoc.com or call 877-655-6798 ◗ New product SecretropinRx SecretropinRx is new Nanoliposomal Amino Acid Complex that is a Potent Growth Hormone Secretagogue. SecretropinRx study show 90% of the patients increase their igf1 and igf1 binding protein 50-200% making this a great alternative to growth hormone. Stop by the University Compounding Booth #503 for a free sample and more information or go to www.secretropinrx.com SPRING 2009 ANTI-AGING MEDICAL NEWS ❘ 159 Supraphysiological Cyclic Dosing of Sustained Release T3 in Order to Reset Low Basal Body Temperature Michael Friedman, ND; Jorge R. Miranda-Massari, PharmD, Michael J. Gonzalez, DSC, PhD, FACN The use of sustained release tri-iodothyronine (SR-T3) in clinical practice, has gained popularity in the complementary and alternative medical community in the treatment of chronic fatigue with a protocol (WT3) pioneered by Dr. Denis Wilson. The WT3 protocol involves the use of SR-T3 taken orally by the patient every 12 hours according to a cyclic dose schedule determined by patient response. The patient is then weaned once a body temperature of 98.6 degrees F has been maintained for 3 consecutive weeks. The symptoms associated with this protocol have been given the name Wilson’s Temperature Syndrome (WTS). There have been clinical studies using T3 in patients who are euthyroid based on normal TSH values. However, this treatment has created a controversy in the conventional medical community, especially with the American Thyroid Association, because it is not based on a measured deficiency of thyroid hormone. However, just as estrogen and progesterone are prescribed to regulate menstrual cycles in patients who have normal serum hormone levels, the WT3 therapy can be used to regulate metabolism despite normal serum thyroid hormone levels. SR-T3 prescription is based exclusively on low body temperature and presentation of symptoms. Decreased T3 function exerts widespread effects throughout the body. It can decrease serotonin and growth hormone levels and increase the number of adrenal hormone receptor sites. These effects may explain some of the symptoms observed in WTS. The dysregulation of neuroendocrine function may begin to explain such symptoms as alpha intrusion into slow wave sleep, decrease in blood flow to the brain, alterations in carbohydrate metabolism, fatigue, myalgia and arthralgia, depression 160 ❘ ANTI-AGING MEDICAL NEWS SPRING 2009 and cognitive dysfunction. Despite all thermoregulatory control mechanisms of the body and the complex metabolic processes involved, WT3 therapy seems a valuable tool to re-establish normal body functions. We report the results of 11 patients who underwent the WT3 protocol for the treatment of CFS. All the patients improved in the five symptoms measured. All patients increased their basal temperature. The recovery time varied from 3 weeks to 12 months. Wilson’s Temperature Syndrome The hallmark symptoms of Wilson’s Temperature Syndrome (WTS), fatigue, anxiety, depression, headaches, insomnia, and muscle aches – are indistinguishable from Chronic Fatigue Syndrome (CFS), except that WTS requires low body temperature as diagnostic of WTS. WTS patients suffer from a wide range of debilitating symptoms , including persistent or relapsing fatigue, muscle aches, insomnia, cognitive dysfunction, and an overall lack of well-being. Low body temperature, depression, and chronic fatigue indicate a hypometabolic state not unlike that of hypothyroidism (1-2). These symptoms resemble those of conventionally recognized hypothyroidism and of CFS (3-5). CFS is characterized by persistent or relapsing debilitating fatigue that has continued for at least 6 months in the absence of any other definitive diagnosis. The source of the fatigue is unknown and the illness is not alleviated with bed rest. Symptoms vary from person to person and fluctuate in severity. CFS patients function significantly below their pre-illness capabilities. Their quality of life is considerably affected. Although patients experience the illness, the symptoms do not have outward identifying physical manifestations (6). Although WTS does not require the strict definition of fatigue lasting for more than 6 months, it still appears SPRING 2009 that in most cases the definition is indistinguishable from CFS, except that WTS includes patients who have mild fatigue and it does not require other symptoms to be present at the same time. CFS includes fever as one potential symptoms, while WTS requires low body temperature. Low Body Temperature. Body temperature is controlled by an elaborate thermoregulatory system that modulates heat production and heat loss so that the core temperature is maintained within a narrow range. The thermoregulatory center of the brain is located in the pre-optic region of the anterior hypothalamus (POAH). Neurons in the POAH act as a thermostat and modulate heat production and heat loss to control the body temperature. Heat is produced from both metabolic and physical activity. Basal metabolic rates vary depending upon body mass, age, environmental temperature, thyroid status, ingestion of food and supplements. In a neutral environment the metabolic rate of the body produces enough heat to maintain a core body temperature at 37o C (98.6o F). When the heat content of the body increases or decreases, the thermoregulatory mechanisms become active. These mechanisms involve interactions between the sweat glands and the nervous, endocrine, cardiovascular, and respiratory systems and are collectively termed the thermoregulatory system. Due to daily circadian variations, normal body temperature fluctuates from a lowest of 36.1o C (97o F) between 2:00 and 6:00 a.m. and a highest of 37.8o C (100o F) between 5:00 and 7:00 p.m. Since many factors can affect the thermoregulatory control, many patients who have low body temperature do not suffer from WTS. Low body temperature in itself is not diagnostic of WTS, without a minimum of one accompanying symptom. However, low body temperature appears as a biological marker that consistently and predictably changes during the progression from illness to health. Although not always noted clinically, CFS patients often self-report low average body temperatures. This low body temperature has been attributed by some researchers to circadian rhythm disruption (7). However, other researchers have found normal mean core body temperatures in CFS patients. It is possible that the subset of CFS patients who suffer from low body temperature were not represented in this study. Alternatively, because CFS patients experience circadian dysrhythmia as demonstrated by their disrupted sleep patterns and salivary cortisol levels, it is possible that the results in this study were affected by the time of day that the study was performed, rather than the mean average of temperatures taken throughout the day (8-9). History of Research of T3 T3 Treatments for euthyroid hypometabolism. The use of T3 for patients suffering from euthyroid hypometabolic states was first described in the early 1950s. Euthyroid hypometabolism was described as a group of symptoms very similar to CFS, including fatigue, lethargy, irritability, headaches, and musculoskeletal pain with the absence of any known underlying cause, including normal TSH levels. Studies performed by Kurland, Sonkin, Title, and Morton reported the efficacy of synthetic T3 (liothyronine sodium) in eliminating the symptoms of hypometabolism. One such study performed by Sonkin prescribed thyroid therapy for 88 patients suffering from euthyroid hypometabolism. He scored each patient for the following symptoms before and after thyroid therapy. The following results indicated that T3 was effective in alleviating euthyroid hypometabolism (see Table 1)(10-12). Table 1. Euthyroid hypometabolism Symptoms Score (Son King LS) Complaint Fatigue Myofascial Pain Depression Headache Nervousness Insomnia Total 88 63 39 4 2 3 Positive Responses 51 46 20 3 0 1 ANTI-AGING MEDICAL NEWS ❘ 161 Psychiatric research in the use of T3 on euthyroid patients has indicated that people need a decreased dose of antidepressants when taking T3, and that it is also a rapid, safe and effective way of treating depression that fail to tricyclics (13-14). This might explain why WTS patients notice decreased depression from the WT3 protocol. Chronic Fatigue Syndrome and Fibromyalgia Syndrome. CFS shares many features with fibromyalgia syndrome (FMS) (15). The predominance of pain or fatigue is the primary means of distinguishing between these two syndromes. Precedence for the use of T3 to treat CFS can be found in recent successful FMS studies. One study found that 75.32% of FMS patients experienced decreased tender point sensitivity as measured by algometry after treatment with 75150 mcg T3 in conjunction with other lifestyle changes, including unspecified increases in aerobic activity, diet changes and nutrient supplementation (16). Other studies found that supraphysiologic doses of T3 produced significant improvement in all measured parameters. These included algometer measurement of tender point sensitivity, American College of Rheumatology measurement of pain distribution, Visual Analog Scale measurement of symptoms intensity, Fibromyalgia Impact Questionnaire scores, and Zung’s Depression Inventory scores. Mean heart rate elevations were noted during treatment as opposed to placebo phases, but there was no report of tachycardia or symptoms of thyrotoxicosis (17-18). The Center of Disease Control (CDC) hypothesizes that CFS might be caused by an initial trigger, such as a stress in the form of an infectious agent, toxin or illness, that can cause a hit and run situation in which once the trigger has happened, the body shifts into a hypo-metabolic state (19). The hypothesis that a subtle thyroid defect might be a secondary response from the initial trigger of stress has not been fully explored, but it has been well documented that the conversion of T4 to T3 decreases under periods of 162 ❘ ANTI-AGING MEDICAL NEWS Table 2. CFS Sympton Score with WTS Protocol Patient Before or AfterRx Fatigue Headaches Anxiety Insomnia Myalgia Patient Mean Patient Temp o F 1 2 3 4 5 6 7 8 9 10 11 Mean Before After Before After Before After Before After Before After Before After Before After Before After Before After Before After Before After Before After 10 4 10 0 9 0 10 3 8 1 10 0 10 0 8 2 8 2 10 0 8 4 9.18 1.45 10 5 0 0 0 0 0 0 9 2 7 0 10 I 2 0 2 I 10 0 4 4 4.91 1.18 8 2 7 I 5 5 10 2 6 3 9 0 0 0 3 2 6 5 7 4 9 7 6.36 2.82 7.6 2.6 5.4 0.4 5.6 1.8 8 1.8 6.2 1.2 7.8 0 8 0.2 5.6 2.6 4.6 2.6 8.6 1.6 7.6 4.2 6.82 1.73 physical injury, as well as, chronic or acute illness (20-21). However, even after the initial injury to the body has passed, the body sometimes has not yet fully recovered. Case Study Discussion WT3 Protocol for CFS. We performed an in-house study in which 11 patients diagnosed with CFS were given the WTS protocol. Each patient was given a physical exam and multi-chemistry panel to rule out any other medically identifiable causes of fatigue. We asked patients to evaluate symptoms of CFS numerically before and after treatment. Treatment was considered complete when the patient was able to maintain a body temperature of 98.6 o F. Table 2 presents the results. A value of “10” represents greatest severity of symptoms, while “1” represents the least severity. A value of “0” represents absence of symptoms. Each patient required a different amount of time to achieve normalization of body temperature. Recovery time varied between 3 weeks and 12 months. 10 2 0 0 7 3 10 3 8 0 7 0 10 0 6 6 2 2 9 2 9 4 7.09 2.00 0 0 10 1 7 1 10 1 0 0 6 0 10 0 9 3 S 3 7 2 8 2 6.55 1.18 97.9 98.6 96.9 98.6 97.7 98.6 97.6 98.6 97.8 98.6 96.9 98.6 97.7 98.7 98.4 98.6 97.5 98.6 96.5 98.6 96.9 98.6 A statistical analysis of these results, conducted by Aikin*, revealed significant differences (see Table 3). After the treatment is discontinued, normally 3 to 6 months after initiation of treatment, the majority of CFS patients report significant and continued improvement in their symptoms. Most patients experience complete resolution of their CFS symptoms persisting years after treatment has been discontinued. Based on clinical observations, many patients are completely freed of fatigue, depression, muscle aches, and other complaints related to CFS. In addition, if it is demonstrated that return of oral temperature to 98.6o F correlates closely with restoration of good health in a high percentage of CFS patients, this may indicate that body temperature in itself is a useful biological marker that can be reset to normal. Since many patients who have low body temperature do not have CFS, we do not propose that it in itself is diagnostic of CFS, but rather that it is a biological marker that consistently and predictably changes during the progression from disease to health. SPRING 2009 Table 3. Statistical Analysis of Symptom Scores after WTS Protocol in CFS Patient Factor Mean Change SE** P-value* Fatigue Headache Anxiety Insomnia Myalgia -7.7 -3.7 -3.5 -5.1 -5.3 0.49 0.51 0.69 0.61 0.35 < 0.001 < 0.001 < 0.001 < 0.0001 < 0.0001 * Aikin, Michael PhD, Senior Investigator Kaiser Permanente for NIH Grant Sustained T3 in the Treatment of Chronic Fatigue Syndrom, Portland Oregon 2002 **Adjusted for Baseline T3 Clinical Research A 2001 study published by Bunevicius et al (22) showed that mood, neuropsychological function, and cognitive abilities were much improved in patients who had taken T3 as opposed to T4 (levothyroxine). Although the participants in the study were hypothyroid, the important aspect in the study was that the patients were already taking exogenous T4 and thus had euthyroid TSH and T4 blood values, but still had hypothyroid cognitive symptoms that were resolved with T3 therapy. It was concluded that T3 had much more of an impact in human physiology than once traditionally thought (22-23). Thyroid Resistance Not only is it possible that a conversion thyroid hormone problem might occur, but there is evidence that thyroid resistance might well be a secondary response to the initial trigger causing CFS. Although the concept of euthyroid fatigue was recognized in conventional medicine in the 1950s, it is not until recently that it is gaining acceptance again in the medical literature. Current medical literature is identifying euthyroid patients who exhibit hypothyroid symptoms as thyroid resistance. Thyroid resistance shares many of the same symptoms as CFS, including headaches, anxiety, fatigue, and recurring sore throats. One postulated mechanism for thyroid hormone resistance found in WTS/ CFS might be due to a dysregulation in the type I interferons (IFN-alpha/beta) pathway. This results in a sustained upregulation of 2’,5’-oligoadenylate synthetases (2-5 OAS). Patients treated with IFN-alpha/beta therapy SPRING 2009 usually complain of severe fatigue as a limiting side effect, perhaps due to the same effect. The 2-5 OAS, IFNalpha/beta instigates the expression of three closely related proteins. The amino acid sequences of the 2-5 OASL proteins display 96% identity with the partial sequence of the thyroid receptor interacting protein (TRIP). It is hypothesized that the 2-5 OASL proteins are TRIPs mechanism of suppressing the TR transactivation and/or possibly destroying the thyroid receptor by the proteasome. This is perhaps how CFS / WTS patients might have normal TSH values yet have a clinical hypothyroid state in CFS/WTS (24). Another mechanism of thyroid resistance found in CFS might be due to a chronic consumptive coagulopathy, which itself might be associated with chronic infections, such as mycoplasmids, and other microbes. It is suggested that supraphysiological doses of thyroid hormone or anticoagulants and anti-infective agents might be effective treatment options. Current research has not found any clear association between an infectious agent and CFS (18). However, based on a multi-causal model, it is possible that some infectious agent might be a contributory cause for a certain subset of patients, or that it might be a trigger for CFS even after the infection is gone (25). Immune system defect might be involved in a certain amount of CFS patients. There is evidence of inappropriate cytokine response (18). The etiological cause is still not known. However, it is hypothesized that it might be due to decreased thyroid function. Thyroid resistance has been associated with increased infections, such as chronic sore throats (26). Stress stimulates the hypothalamicpituitary-adrenal axis, or HPA axis, which leads to increased levels of cortisol. Increased levels of cortisol inhibit thyroid function (27). Some CFS studies have found cortisol levels to be lower than healthy controls (18). However, since studies have not found conclusively that cortisol replacement is an effective treatment, cortisol deficiency as the main causative factor for CFS does not seem promising. Low thyroid function has been shown to affect cortisol levels (28). Some researchers have found that hypothyroidism increases cortisol levels and others have found that it decreases cortisol levels (29). In conclusion, CFS/WTS might have a variety of causative factors that compromise immune system by stress or other insults that come from viruses, bacteria, toxins, or other triggering agents that upset the body’s normal functioning. After the initial insult to the body, CFS/WTS symptoms remain, perhaps due to thyroid hormone resistance or peripheral thyroid hormone conversion problems. Regardless of the mechanism, WT3 therapy seems to restore metabolism to the vast majority of patients. SR-T3 (WT3) Protocol In the clinical setting, T3 therapy is not used to correct a measurable thyroid hormone deficiency, but rather to recalibrate metabolism and body temperature patterns. Dr. Wilson developed the SR-T3 treatment protocol over a 2-year period via empirical observations of treating patients with intractable fatigue. He subsequently treated more than 5,000 people over a period of 4 years. The Wilson’s Temperature Syndrome. Currently there is an estimated 1,000 American doctors who use the therapy for fatigue and other WTS symptoms. Unique Features The unique features of the Wilson T3 (WT3) protocol that distinguish it from conventional T3 therapy are that ANTI-AGING MEDICAL NEWS ❘ 163 it uses a sustained release form of T3, as opposed to Cytomel, and it is cyclic in its administration, with the dose and cycle-length adjusted according to patient symptomatic response (30). The subjects are treated with liothyronine compounded in a hydrophilic matrix system, employing hydroxypropylmethylcellulose (HPMC) formulated to be taken every 12 hours. The liothyronine is synthetically made and does not differ from any standard pharmaceutical preparation of T3, except that it is compounded with the sustained release agent methylcellulose. Clinical observation using SR-T3 shows that prolonged exposure to T3 changes patient susceptibility to the drug, necessitating alterations in dose. For example, the first cycle of SR-T3 may require 90 mcg of T3 BID to obtain a normal temperature, while the second cycle may require only 45 mcg of T3 to achieve the same temperature. Body temperature is used in determining dosage and cycle length. The original protocol used liothyronine sodium (Cytomel), but undesirable side effects (e.g., irregular heartbeat and occasional atrial fibrillation) prompted the exclusive use of SR-T3. The SR-T3 produced fewer and milder side effects. However, a significant amount of patients still suffer from some symptoms, including increased awareness of heartbeats, heart palpitations, increased heart rate, irritability, shakiness, fatigue, and headaches. These effects are usually successfully treated with a “test dose” of T4. A test dose of T4 is a small dosage (.0125-.025 mg) of levothyroxine taken to dampen the effects of T3 therapy through competitive inhibition of T3 by T4. T4 has 25% the potency of T3, and administration of T4 usually decreases or eliminates the side effects of T3 therapy within 45 minutes. The clinical experience of numerous physicians suggests that T3 compounded in a hydrophilic matrix system (sustained release system) in capsules taken every 12 hours provides a predictable, well-tolerated means to influence body temperature patterns and alleviate the debilitating symptoms experienced by WTS patients. Once symptoms 164 ❘ ANTI-AGING MEDICAL NEWS improve or resolve, patients are able to wean off SR-T3 therapy. Patients often report no return of symptoms after the treatment has been discontinued. Some patients do relapse, but a very short cycle of SR-T3 will usually bring them back to normal. Another important consideration in the metabolic regulation related to proper thyroid hormone function is iodine consumption, absorption and utilization. The main function of iodine is the synthesis, storage and secretion of thyroid hormone. Iodine possesses wide antimicrobial functions and adequate iodine levels are required for proper immune function. Iodine is also present in large amounts in other tissues such as in the breast tissue, salivary glands, brain and extracellular fluids. It is excreted in the urine. Iodine deficiency should be evaluated to avoid secondary physiological dysregulations and its associated risk factors. If deficient, iodine supplementation is indicated. In addition, it must be recognized that the cellular transport mechanism for iodine can be defective and it has been reported that this problem can be corrected with the administration of vitamin C (31). Long-term Success The use of T3 outside of the WT3 protocol has not been shown to normalize body temperature. Dr. Wilson’s clinical experience indicates that longterm success in resetting metabolism and alleviating symptoms using the cyclic-T3 therapy proposed for this study seems to be related to holding body temperatures close to 98.6o F for a specified period of time. Patients whose body temperatures have been successfully raised to or near 98.6o F show sustained positive responses after the treatment is discontinued. Patients whose oral temperatures are not successfully raised to that level seem to retain less benefit from the treatment. It is known that exogenous T3 suppresses T4 levels due to negative feedback inhibition of TSH. It is speculated that T4 suppression is an important effect of the Wilson protocol that is essential to its effectiveness. Often more than one cycle of SR-T3 therapy may be needed to increase body temperature to near-normal values. In many cases, one or more cycles reaching a maximum dose of SR-T3 (90 mcg b.i.d.) fails to raise the patient’s temperature to normal. Then, the temperature may reach normal on a subsequent cycle at a lower dose. In such cases, we speculate that greater T4 suppression is achieved with each successive cycle until the body temperature reaches normal. Serial measurements of serum free T4 may help to elucidate this proposed mechanism. It is speculated that T4 suppression from repeated cycles of SR-T3 therapy results in lower serum levels of T4 and RT3, and therefore less competitive inhibition of T3. This suppression may increase from cycle to cycle, increasing T3 expression with each cycle. Increased expression of T3 may result in greater T4 suppression until body temperature is finally normalized and the metabolism is “re-calibrated.” Once temperature is normalized, decreased SR-T3 is needed on subsequent cycles to maintain normal body temperature. Clinical evidence thus far indicates that patients can safely discontinue the sustainedrelease T3 therapy and maintain benefits once oral body temperatures are held at 98.6o F for a specified period of time. After the treatment is discontinued, normally 3-6 months after initiation of treatment, the majority of WTS patients report significant and continued improvement in their symptoms. Many patients experience complete resolution of their WTS symptoms persisting years after treatment has been discontinued. Based on clinical observations, many patients are completely freed of fatigue, depression, muscle aches and other complaints related to WTS. Clinical Studies Most studies on thyroid hormone supplementation have been done using levothyroxine. There is current controversy over the effects of thyroid hormone supplementation on osteopenia. Most studies indicated no effect (32-33) while one study of long term suppressive dose of T4 did show an increase in bone loss (16) SPRING 2009 Clinical studies using supraphysiological doses of T3 ranging from 93.75 to 105 mcg daily in euthyroid fibromyalgia, over an 8 month period indicated no change in serum calcium and phosphorous, nor in bone densitometry vs. placebo. However there were higher levels of urinary N telopeptides. Liver function tests were no different vs. placebo at 4- month follow-up, serum creatinine and calcium were also normal, indicating no change in muscle mass. Mean heart rate significantly increased from 68.5 bpm in placebo vs. 83.94 bpm in T3 patients during the study. No patients developed tachycardia. There was no significant difference in diastolic or systolic blood pressure in T3 or placebo group. Serial EKG indicated no significance except that the placebo QT intervals shortened within the normal range during T phases (34). Adverse reactions to liothyronine sodium are generally due to therapeutic over-dosage, and thus are characterized by the typical symptoms of hyperthyroidism (e.g., tachycardia, irritability, nervousness, and increased bowel motility). In rare instances, allergic skin reactions have been observed in patients taking liothyronine sodium.u REFERENCES 1. Karkal, S., Overcoming diagnostic and therapeutic obstacles in hypothyroidism. Emergency Medicine Reports, 1990;11:219-227. 8. Shibui K, Okawa M, Uchiyama M, Ozaki S, Kamei Y, Hayakawa T and Urata J. Continuous measurement of temperature in non-24 hour sleep-wake syndrome. Psychiatry Clin Neurosci, 1998;52:2367. 9. Title CR. Effects of triodothinoine in patients with metabolic insufficiency. J Am Med Assoc 1956;162: 271. 25. Refetoff S, Weiss RE and Usala SJ. The syndromes of resistance to thyroid hormone. Endocrinol Rev 1993; 14: 348-99. 26. Braverman LE and Utiger RD. Introduction to hypothyroidism, in: Werner and Ingbar’s The Thyroid: A Fundamental and Clinical Text. 1991, Lippincott. p. 919-920. 10. Kurland GS, Hamolsky MW and Feedberg AS. Studies in non-myxedematous hypermetabolism: The clinical syndrome and the effects of triiodothyronine, alone or combined with thyroxine. J. Clin Endocrinol 1955;15: 1354. 27. Scott LV, Svec F and Dinan T. A preliminary study 11. Sonkin LS. Myofascial pain due to metabolic disorders: diagnosis and treatment in Myofascial pain and Fibromyalgia: Trigger Point Management, Rachlin, ES. Ed. 1994, Mosby; St. Louis. p.45-60. 28. Iranmanish A, et al. Dynamics of 24-hour endo- 12. McIntyre, R.S., et al., What to do if an initial antidepressant fails? Can Fam Physician, 2003;49:44957. of dehydroepiandrosterone response to low-dose ACTH in chronic fatigue syndrome and in healthy subjects. Psychiatry Res 2000; 97:21-8. genous cortisol secretion and clearance in primary hypothyroidism assessed before and after partial thyroid hormone replacement. J Clin Endocrinol Metab 1990; 70: 155. 29. Gyulai L, Bauer M, Garcia-Espana F, Hierholzer 13. Joffe, R.T., et al., Predictors of response to lithium and triiodothyronine augmentation of antidepressants in tricyclic non-responders. Br J Psychiatry, 1993;163:574-8. J, Baumgartner A, Berghofer A and Whybrow PC. 14. Lowe, JC, Thyroid status of 38 fibromyalgia patients: implications for the etiology of fibromyalgia. Clinical Bulletin Myofascial Ther. 1997;2:47-64. 2001; 66: 185-91. 15. Lowe JC, Garrison RL, Reichman AJ, Yellin J, Thompson M, and Kaufman D. Effectiveness and safety of t3 therapy for euthyroid fibromyalgia: a double-blind placebo-controlled crossover study. Clinical Bulletin Myofascial Ther., 1997;2:31-58. 16. Lowe JC, Reichman AJ, and Yellin J, The process of change during T3 treatment for euthyroid fibromyalgia: A double-blind placebo-controlled crossover study. Clin. Bull. Myofascial Ther., 1997;2:91-124. 17. Lowe JC, Garrison RL, Reichman A and Yellin J, Triiodothyronine (T3) treatment of euthyroid fibromyalgia: A small-N replication of a doubleblind placebo-controlled crossover study. Clin Bull Myofascial Ther, 1997;2:71-88. 18. Primary Care Provider Education Project, Chronic Fatigue Syndrome: A Diagnostic and Management Challenge (2003), Center for Disease Control and Prevention. p. 3. Bone mineral density in pre- and post-menopausal women with affective disorder treated with longterm L-thyroxine augmentation. J Affect Disord 30. Wilson, E. Denis, Doctor’s Manual for Wilson’s Temperature Syndrome, Muskeegee Medical Publishing, Lady Lake, FL 1991; p. 112. 31. Abraham GE and Brownstein D. Evidence that the administration of Vitamin C improves a defective cellular transport mechanism for iodine: A Case Report. Posted at www.optimox.com. 32. Van Den Eeden SK, Barzilay JI, Ettinger B and Minkoff J. Thyroid hormone use and the risk of hip fracture in women > or = 65 years: a case-control study. J Women’s Health 2003; 12: 27-31. 33. Sijanaovic S and Karaner I. Bone loss in pre-menopausal women on long term suppressive therapy with thyroid hormone. 2001, Medscape Women’s Health. 34. Wilson D., personal communication. May 20, 2002. 2. Lam, K.S., et al., Vasoactive intestinal peptide in the anterior pituitary is increased in hypothyroidism. Endocrinology, 1989;124:1077-84. 19. Felicetta J. effects on Illness on Thyroid Function Tests. Postgrad Med 1989; 85: 213-220. 3. Kales, A., et al., All night sleep studies in hypothyroid patients, before and after treatment. J Clin Endocrinol Metab, 1967;27:1593-9. 20. Schimmel M and Utiger RD. Thyroidal and peripheral production of thyroid hormones. Review of recent findings and their clinical implications. Ann Intern Med 1977; 87: 760-8. cian and medical herbalist. He graduated from 21. Refetoff S. Resistance to thyroid hormone: an historical overview. Thyroid 1994; 4: 345-349. ogy at the University of Bridgeport in Connecti- 22. Bunevicius R, Kazinkevicius R, Prange AJ Jr. Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism. N Engl J Med 1999; 340: 424-9. Canadian College of Naturopathic Medicine. 4. Eisinger J, Plantamura A, Ayavou T. Glycolysis abnormalities in fibromyalgia. J Am Coll Nutr, 1994;13:144-8. 5. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG and Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group. Ann Intern Med, 1994;121:953-9 6. Williams G, Pirmohamed J, Minors D, Waterhouse J, Buchan I, Arendt J, and Edwards R H. Dissociation of body-temperature and melatonin secretion ciradian rhythms in patients with chronic fatigue syndrome. Clin Physiol 1996;16:327-37. 23. Englebienne P, Verhas M, Herst CV and De Meirleir K. Type I interferon induces proteins susceptible to act as thyroid receptor (TR) co-repressors and to signal the TR for destruction by the proteasome: possible etiology for unexplained chronic fatigue. Med Hypotheses 2003; 60: 175-80. 7. Fukuda K, Ishhara K, Takeuchi T, Yamamoto Y and Inugami M. Core temperature pattern and self-rated lifestyle. Psychiatry Clin Neurosci 1998; 52:243-45. 24. Garrison RL and Breeding PC. A metabolic basis for fibromyalgia and its related disorders: the possible role of resistance to thyroid hormone. Med Hypotheses 2003; 61: 182-9. SPRING 2009 ◗ Michaël Friedman, ND is a naturopathic physithe Canadian College of Naturopathic Medicine in 1998 and was a professor of endocrinolcut. He currently lectures for the ICS series at the He is also the founder and director of the Annual Restorative Medicine Conference. Dr. Friedman is the author of the medical textbook Fundamentals of Naturopathic Medicine and Healing Diabetes. His research on the use of SR T3 has been published by the University Puerto Rico Medical School. Dr. Friedman has lectured at three naturopathic and allopathic medical schools including NCNM, UB, CCNM and at the Dehradun Medical School of Physicians and Surgeons in India. 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Palmetto Park Boca Raton, FL 33486 USA Your Practice. Our Solution. The Future. BodyLogicMD is the nation’s largest franchise of highly trained physician-owned practices specializing in bioidentical hormones integrated with customized fitness and nutrition programs. With 23 offices nationally and rapidly expanding, we offer you a quick and successful approach to grow your practice. Find out about our Risk Free Guarantee. Florida Detox and Wellness Institute offers a more scientific approach to addiction treatment, incorporating recent advances in brain science, specifically research derived from PET and SPECT scan studies at the National Institute of Drug Addiction (NIDA), the Amen Clinics and major universities. 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Orlando, FL 32814 USA This program has been designed to teach clinicians how to restore optimal health through restoring hormones and nutrients, removing toxicities and rebalancing the mind and body. This is a 5 day preceptorship seeing and managing patients in our practice. A complete protocol book will be provided. 407-478-9797 www.sajune.com Erchonia Medical 2021 Commerce Dr. McKinney, TX 75069 USA 176 ❘ 925 Commercial St. Palo Alto, CA 94303 USA 650-493-9155 www.sciton.com Vita-Mix Corp 8615 Usher Rd. Cleveland, OH 44138 USA 800-848-2348 www.vitamix.com WTSmed 214-544-2227 www.erchonia.com ANTI-AGING MEDICAL NEWS 93 Barre St., Ste. 1 Montpelier, VT 05602 USA 802-420-5801 www.wtsmed.com SPRING 2009 UNIVERSITY COMPOUNDING PHARMACY Specializing in: v v v v Bio-Identical Hormone Replacement Physician Training Seminars Non-Commercially Available Formulations Alternate Routes of Administration 800-985-8065 | v v v v Discontinued & Off-Patent Drugs In-Office Use Supplies Suppositories (Vaginal & Rectal) Sterile Injectable Medications www.ucprx.com University Compounding Pharmacy is a Board Certified Compounding Pharmacy BUYERS Guide Zija International Health Secrets USA 731 S. Hwy. 101, Ste. 2-H Solana Beach, CA 92075 USA 760-815-6474 www.drinklifein.com 24141 Ann Arbor Trail Dearborn Heights, MI 48127 USA 313-561-6800 www.healthsecretsusa.com Homefirst® Natural Pharm Source, LLC Nutraceuticals Aminocare Products, L.P. 9432 Old Katy Rd., Ste. 200 Houston, TX 77055 USA Daiwa Health Development, Inc. 1411 W. 190th St., Ste.375 Gardena, CA 90248 USA 713-335-5675 www.aminocare.com 7514 N. Saint Louis St. Skokie, IL 60076 USA Life Extension 1100 West Commercial Blvd. Ft. Lauderdale, FL 33309 USA In search of helping people to live healthly lives, Daiwa Health Development has successfully introduced Plasmanex1, an effective coagulation modulator™, a natural enzyme extracted by a patented fermentation production process to support healthly blood circulation, in addition to their already popular product, BRM4, a unique immune modulator, derived from rice bran. 866-395-1881 www.store.homefirst.com Earn Thousands with Life Extension® Nutraceuticals, including the New Weight Loss Supplement Shown to Shed 28 Pounds in 10 Weeks! Invest in the health of your patients and your practice by becoming a Life Extension Wholesaler. 20% Show Discount plus Free Testosterone For Life book For New Wholesalers Call. 888-884-3657 www.lef.org LivOn Laboratories 877-434-3633 www.dhdmed.com DaVinci Laboratories 20 New England Dr. Essex Junction, VT 05453 USA 800-325-1776 www.davincilabs.com Designs for Health 2 North Rd. East Windsor, CT 06088 USA 178 ❘ Natural Clinician LLC 47 Center Dr. Little Falls, NJ 07424 USA 973-256-4660 www.naturalclinician.com 3017 Business Park Dr. Stevens Point, WI 54481 USA 800-332-2351 www.orthomolecularproducts.com PhysioLogics 800-245-4440 www.douglaslabs.com Fuji Health Science 3 Terri Ln., Ste.12 Burlington, NJ 08016 USA 1-866-682-6193 www.livonlabs.com Ortho Molecular Products 800-847-8302 www.designsforhealth.com Douglas Laboratories 600 Boyce Rd. Pittsburgh, PA 15205 USA 2654 W. Horizon Ridge Pkwy., Ste.B-5 Dept. 108 Henderson, NV 89052 1170 Valley Brook Ave. Lyndhurst, NJ 07071 USA 800-765-6775 www.physiologics.com Rejuvenation Science 609-386-3030 www.fujihealthscience.com ANTI-AGING MEDICAL NEWS 811 N. Catalina Ave., Ste. 3208 Redondo Beach, CA 90277 USA 888-737-3588 ww.Rejuvenation-Science.com SPRING 2009 ANEWrx is an advanced compounding pharmacy focused on the special needs of physicians and patients to tailor multiple-drug combinations, special formulations, and alternative dosage forms to the unique health care requirements of the individual. Our state-of-the art clean room facility and tightly controlled processes and practices assure the content, purity, and integrity of the compounded medication preparations that we dispense. Our re-formulating capability includes such skills as the compounding of sublingual dosage forms of select medications typically administered either by injection or enteric routes. ANEWrx staff are trained, skilled, and experienced in the compounding of both non-sterile and sterile medication preparations. Please Contact Us About Your Needs For Our Specialized Services in the Areas of: Age Management • • • • • • • • Bioidentical hormone replacement Andropause therapy Testosterone Sermorelin hCG for injection lyophilzed hCG for sublingual lyophilized Anti-wrinkle creams and ointments GHRP-6 Other Specialties • Sexual dysfunction treatment including: ∙ Libido gels ∙ Tri-mix injections • Weight reduction preparations • Pain management ANEWrx quality management practices assure physicians and patients of the consistent purity and potency of every dose in every prescription. Our pharmacists and technicians use only ingredients of known pedigree and the highest quality in their compounding processes which conform to the standards promulgated by the IACP, ASHP and USP. For special pricing and more information, visit us at Booth #310. Call Today! 877-788-8908 www.ANEWrx.com BUYERS Guide T.A. Sciences, Inc. 24 East 64th St., 5th floor New York, NY 10065 USA Hallandale Pharmacy 212-588-8805 www.tasciences.com 1109 E. Hallandale Beach Blvd. Hallandale, FL 33009 USA 954-455-3822 www.hallandalerx.com Medaus Pharmacy Vital Nutrients 45 Kenneth Dooley Dr. Middletown, CT 06457 USA 888-328-9992 www.vitalnutrients.net 888-401-0967 www.cpmedical.net 1-800-449-1130 www.ultimateglucosamine.com 318 Blackwell St., Ste.240 Durham, NC 27701 USA 919-682-8800 www.testopel.com 801-984-1150 www.detoxamin.com Arasys Perfector Ion Magnum Youth Juice 1875 3rd Ave. San Diego, CA 92101 USA 707-525-3784 www.neilmed.com Sports / Fitness / Physical Therapies World Health Products, LLC 12685 South 125 East Draper, UT 84020 USA 601 Aviation Blvd. Santa Rosa, CA 95403 USA Slate Pharmaceuticals Inc. Wellesley Therapeutics Inc 200 Gerrard St. E, Ste. 307 Toronto, ON M5A 2E6 Canada 800-526-9183 www.medaus.com NeilMed Pharmaceuticals Vitamin Research Products 4610 Arrowhead Dr. Carson City, NV 89706 USA 2637 Valleydale Rd. Birmingham, AL 35244 USA 619-683-2005 www.ucprx.com 7773 Waikapu Loop Honolulu, HI 96825 USA The vision of naturally enhancing rejuvenation and healthy anti-aging drives our commitment to push the boundaries of science into new discoveries to deliver the best next generation solutions to Facial Rejuvenation and Body Sculpting. At Arasys Perfector, LLC we challenge the bounds of science and creativity to deliver on tomorrow’s capability. 808-395-0656 www.arasysperfector.com Pharmaceutical Auxilium Pharmaceuticals, Inc. 40 Valley Stream Pkwy. Malvern, PA 19355 USA 484-321-2126 www.auxilium.com Discount Marketing Corp 9 E-Pelican St. Naples, FL 34113 USA Bellevue Pharmacy Solutions Ondamed Inc. 1034 S. Brentwood Blvd., Ste.102 St. Louis, MO 63117 USA 80 Waterview Terrace New Windsor, NY 12553 USA 180 ❘ ANTI-AGING MEDICAL NEWS 314-727-8787 www.bellevuerx.com 888-476-9256 www.discount-marketing.com 845-496-6673 www.ondamed.net SPRING 2009 6432 S Pulaski Chicago, IL 60629 USA FoodPharmacy Software 800-433-3535 www.teamdoctorsstore.com Stem Cell Therapies 75 Josie’s Ln. Bozeman, MT 59718 USA BUYERS Guide Team Doctors Store 866-411-1122 www.foodpharmacy.com Ideal Protein 178 Jean Proulx, Ste 202 Gatineau, QC J8Z1V3 Canada 866-314-4447 www.idealprotein.com German Society for Thymus Therapy Harvestehuder Weg 65 Hamburg, 20149 Germany +49-1805-849687 www.thymus-therapie.org Life Extension 1100 West Commercial Blvd. Ft. Lauderdale, FL 33309 USA Ondamed Inc. 80 Waterview Terrace New Windsor, NY 12553 USA 845-496-6673 www.ondamed.net Earn Thousands with Life Extension® Nutraceuticals, including the New Weight Loss Supplement Shown to Shed 28 Pounds in 10 Weeks! Invest in the health of your patients and your practice by becoming a Life Extension Wholesaler. 20% Show Discount plus Free Testosterone For Life book For New Wholesalers Call. 888-884-3657 www.lef.org Regenocyte Therapeutic 3301 Bonita Beach Rd., Ste. 315 Bonita Springs, FL 34134 USA 866-216-5710 www.regenocyte.com MaxGXL Weight Management 1326 Armacost Ave., Ste. 5B Los Angeles, CA 90025 USA 310-478-3604 www.maxgxl.com/christian Ondamed Inc. Arasys Perfector Ion Magnum 7773 Waikapu Loop Honolulu, HI 96825 USA The vision of naturally enhancing rejuvenation and healthy anti-aging drives our commitment to push the boundaries of science into new discoveries to deliver the best next generation solutions to Facial Rejuvenation and Body Sculpting. At Arasys Perfector, LLC we challenge the bounds of science and creativity to deliver on tomorrow’s capability. 808-395-0656 www.arasysperfector.com 80 Waterview Terrace New Windsor, NY 12553 USA Take Shape for Life 135 South Sierra Ave., Ste 2 Solana Beach, CA 92075 USA 845-496-6673 www.ondamed.net Helping physicians set up a turnkey, medically supervised weight managment program using lifestyle coaching and Medifast meal replacements. Receive FREE comprehensive training and marketing strategies to make your practice more profitable and rewarding. 888-539-9975 www.WeightLossDoctor.net Dr. G’S Weight Loss & Wellness Program 21097 NE 27th Ct., Ste. 590 Aventura, FL 33180 USA SPRING 2009 305-933-3232 www.drgsweightloss.com ANTI-AGING MEDICAL NEWS ❘ 181 WORLD COUNCIL FOR CLINICAL ACCREDITATION (WCCA) Strategically Position Your Anti-Aging Clinic or Medical Spa as An A4M/WCCA Accredited Facility of Excellence* Benefits of A4M/WCCA Facility Accreditation: • Prevail amongst generic antiaging clinics and spas with distinguished status as a professionally accredited clinical facility • Gain a marketing edge against your competition through enhanced positioning at the Online Clinic Locator at The World Health Network, www.worldhealth.net, the Internet’s leading anti-aging portal • Receive direct patient referrals from the Patient Recruitment and Education Program (PREP), an initiative affiliated with the A4M’s LEXCORE Research Study SET YOUR ANTI-AGING CLINIC OR MEDICAL SPA APART FROM THE COMPETITION