CAMPO ™ PLANTSERVATIVES WSr - in
Transcription
CAMPO ™ PLANTSERVATIVES WSr - in
Lonicera Caprifolium Lonicera Japonica Plant Lonicera Japonica in flowering buds CAMPO COSMETICS (S) PTE LTD Level 31, 6 Battery Road Singapore 049909 Tel: (65) 62837781 Fax: (65) 62828823 E-mail: [email protected] Web site: http//www.campo-research.com CAMPO ® Multi-Purpose Cosmetic Base Chemicals & Active Ingredients CAMPO ® Novel Functional Active Cosmetic Ingredients and Raw-Materials Campo Plantservatives CAMPO ™ PLANTSERVATIVES WSr The Botanical Preservative Plantservative WSr (Japanese Honeysuckle – Lonicera Japonica) is fully active liquid preservative isolated from herb, namely Lonicera Japonica (Japanese Honeysuckle) and Lonicera Caprifolium and is suitable for the antimicrobial protection of cosmetic and pharmaceutical applications. The following advantages of are emphasized: Broad-spectrum antimicrobial activities – Plantservative WSr exhibit rapid, microbicidal activity against Gram – negative bacteria, as well as Gram Positive bacteria, yeasts and molds. Suitable concentrations (0.5-2.0%) show rapid, bactericidal activities, even against such species are Pseudomonas Aeruginosa, which is resistant to many synthetic preservatives and is a frequent contamination of preparations in the tropical and semi-tropical countries. Easy incorporation. Being a liquid, miscible with many organic solvents, surfactants and emulsifiers. Is easily incorporated into the materials to be preserved. Good compatibility. Is chemically inert and therefore compatible with the majority or types of chemical compounds. At the correct concentrations, it maintains strong, extensive efficiency in the presence of such materials as proteins, gums, anionic and maintains its antimicrobial activities in acidic, neutral, and mildly alkaline pH conditions. Does not cause any changes in color or odor to the final products, and this is very particularly important in cosmetic preparations. Non-volatile. Is non – volatile and there should be no loss of preservative activities from the product, even after prolonged exposure to air or in storage. High Stability-Remains fully stable over a wide permittance range of pH and temperature range. There is no significant degradation when strongly heated in the pH range 3-8. Aqueous solution will without detriment to the preservation activities. Low toxicity-A comprehensive toxicological data has been shown to be that this plant extract with preservative activities has low toxicity, being totally non-irritant to skin, mucous membranes and well tolerated by eye at suggested concentrations. Japanese Plantservative WSr has been shown to be devoid of skin sensitizing effects. Fully biodegradable at the extremely dilute conditions as found in the effluents is biodegradable and thus presents no pollution hazard. CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives Plantservative WSr Bacteriostatic and fungistatic activity: Plantservative WSr exhibits effective microbiostatic activity against a wide broad-spectrum of bacteria, molds, and yeast at concentration of 0.25 %( w/v) and less. This is a first of the series of botanical based preservative(s) exhibit such a novel MIC rate and totally and food and medicinal plant in the oriental cultures of China, Japan, and Korea. This microbiostatic activity is illustrated by the following table, which shows the minimum inhibitory concentration (MIC) of Plantservative WSr against examples of different groups of microorganisms. The values were determined in liquid media with readings of bacteria growth after 7days at 32deg`Cent, and for fungal growth after 30days at 25deg`Cent in solid media. Test Species MIC of Plantservative WSr (%W/v) BACTERIA Staphylococcus Streptococcus haemolyticus Lactobacillicus buchneri Bacillus subtilis Pseudomonas fluorescens Pseudomonas aeruginosa Escherichia coli Enterobacter agglomerans Klebsiella aerogenes Proteus vulgaris 0.25 0.25 0.10 0.15 0.75 0.25 0.25 0.15 0.75 0.25 YEASTS Candida albicans Saccharomycas cerevisiae 0.25 0.25 MOLDS Penicillium notatum Trichoderma viride Aspergillus niger 0.25 0.60 0.75 It should be noted that the minimum lethal concentration of Plantservative WSr for most microbial species is the same as its MIC value. Plantservative WSr Microbicidal action in aqueous solution The following table shows the rapid lethal effect exhibited and obtained by 0.25% in phosphate buffer,pH 5.0. Microbial Species Staphylococcus aureus Escherichia coli Pseudomas aeruginosa Pseudomas fluorescens Candida albicans Penicillium crustaceum 0.25 % PLANTSERVATIVE WSr 15Mins 30Mins 1Hr 2Hr 1Day + + + + + + - Legends + - = = Growth after sub culture was added into inactivating medium. No growth was observed after sub culture was added into inactivating medium. CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives CAMPO ™ PLANTSERVATIVES WSr TECHNICAL SPECIFICATION Botanical Origin : Part Used Primary Extraction solvent Final carrier Vehicle : : : Plantservative WSr is an extract of flowers of Lonicera Caprifolium (Caprifoliacee) and Lonicera Japonica (Caprifoliacee) Flowers Buds Carbon Dioxide Water Approx Raw Material Extraction Composition INCI Names Lonicera Caprifolium Extract Lonicera Japonica Extract Aqua / Water CAS 84603-62-3 223749-799-9 773218-5 EINECS 283-263-6 N/A 231-7912 Approx Raw Material Extraction Composition % Approx up to <45 Approx up to <20 Approx up to <35 INIC Name : Lonicera Caprifolium Extract Lonicera Japonica Extract Aqua / Water Lonicera Caprifolium (Honeysuckle) Flower Extract Lonicera Japonica (Honeysuckle) Flower Extract Aqua / Water 95-180-3004 PLANT WSr 54FYY99 15706999776 Astringent, skin conditioning 0,3 - >1% CTFA Name : Product # USA FDA Code USA FDA Registration # Cosmetics use Suggested usage concentration : : : : : Other Industrial uses : Broad-Spectrum antimicrobials,Broad-Spectrum anti-fungals & Broad-Spectrum anti-yeasts Suggested usage concentration (other industrial uses) : 5% - <10% Poultry & Veterinary uses : As natural plant extract with Broad-Spectrum anti-biotical properties, Broad-Spectrum anti-viral properties, Broad-Spectrum anti-gram positive micro organisms properties & Broad-Spectrum anti-gram negative micro organisms properties Suggested usage concentration (Poultry & Veterinary uses) : >1.5% v/v - <2.5%v/v (volume to volume) Specification Parameter Analysis Physical Form Colour Odour Specific Gravity (20°C) Refractive Index (20°C) pH(20°C) (100% Concentrate) Dry Residue (160deg.C/ 2hrs) Water Solubility Pesticide Content Heavy Metals (Total) As, Pb, Hg Total Germs Total Yeast/Mold Preservation Specification Range Liquid Clear Colorless Yellowish tint to yellow clear Ale Faint characteristics 1,120 – 1,320 1,300 – 1,450 8.00 – 12.00 30- 70% 30.0 - 57.0% Water. Clearly hazy soluble None < 0,005 ppm <100 Cfu/ml - Non-Pathogenic < 100 cfu/ ml None CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Methods Visual Visual Oilfactory Paar, DMA35 DGF IV C (52) DGF H III (92) Mettler 16J Pflanzaniaschuttal 1989 Ph.Eur2.6.12 (97) Ph.Eur2.6.12 (97) Ph.Eur2.6.12 (97) - Campo Plantservatives Campo Cosmetics (S) Pte Ltd TECHNICAL SPECIFICATIONS PRODUCT Name: (Campo Research) CAMPO PLANTSERVATIVE WSr Other Trade Names: (Campo Research) Lonicera Japonica Extract Water Soluble CAMPO PRODUCT #: CTFA TRADE NAME: 95-180-3004 PLANTWSr Latin Name: Lonicera Caprifolium Syn. Latin Name: Lonicera japonica Var. Caprifolium INCI Name: Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Lonicera Japonica (Honeysuckle) Flower Extract (And) Water / Aqua CTFA Monograph ID: 8845 - Lonicera Caprifolium (Honeysuckle) Flower Extract 9690 - Lonicera Japonica (Honeysuckle) Flower Extract 9423 – Water INCI Name EU: Lonicera Caprifolium Extract (And) Lonicera Japonica Extract (And) Water / Aqua INCI Names (Proposed): Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Lonicera Japonica (Honeysuckle) Flower Extract (And) Water / Aqua PLANTSERVATIVE JCID (Japan): User's/Client's Name: See Batch lot COA CAS# (CAS Name): 84603-62-3 (Lonicera Caprifolium) 2237 49 799-9 (Lonicera Japonica) 773218-5 (Water / Aqua) EINECS # (EINECS Name): 283-2636 (Lonicera Caprifolium) N/A (Lonicera Japonica Extract) 231-7912 (Water / Aqua) EU INCI 2001/ EINECS BIOLOGICAL FUNCTIONS: BIOLOGICAL EXTRACT HAIR CARE ENHANCING AND SKIN-CARE ENHANCING, ASTRINGENT, MASKING BIOLOGICAL FUNCTIONS EU INCI RESTRICTIONS: NONE EU INCI LAST MODIFICATIONS: 28 CHEM/IUPAC NAME: Lonicera Caprifolium Extract is an extract of thee flowers of Honeysuckle, Loniceera Caprifolium, Caprifoliaceae. TH NOVEMBER 1999 UNITED STATES FOOD & DRUG ADMINSTRATION (U.S. FDA) PRODUCT CODE# 54FYY99 UNITED STATES FOOD & DRUG ADMINISTRATION (U.S. FDA) REGISTRATION # 15706999776 BATCH/LOT # SPECIES PARTS USED See Batch lot COA Lonicera Japonica Lonicera Caprifolium Flower buds CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives RAW MATERIAL – ORIGIN DATE OF HARVEST RAW MATERIALS PARTS/QUANTITY JAPAN, MANCHURIA, INNER MONGOLIA & OUTER MONGOLIA See Batch lot COA See Batch lot COA COMMENTS INCOMPATIBILITIES Contains No Synthetic PARABENS This material may be leaching in negligible trace amounts of Methylamine (Hexamine) and other Formol releasing (But below Japan & EEC regulatory limits of Formaldehyde) hardening components of liquid resins of Epoxy and / or resins of phenolic of plastic process of plastic packaging. INCOMPATIBILITY ASSAYS This material is incompatible with Schiff Reagents, and Assays Methods of Schiff Reaction, or Modified Schiff Reaction Assays, via Colorimetric Techniques or via HPLC. SUGGESTED COMPATIBLE ASSAYS Suggested Compatible Assays Methods “SPECTROPHOTOMETRIC METHOD AOAC OFFICIAL METHOD 931.08 & 964.21) as compatible ALTERNATIVE assays to any Assays of Schiff Reactions via Colorimetric or HPLC. Recommended Mandatory Ingredient Listing of INCI Name: Approx up to <45% Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Approx up to <20% Lonicera Japonica (Honeysuckle) Flower Extract (And) Approx up to <35% Water / Aqua Approx up to <45% Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Approx up to <20% Lonicera Japonica (Honeysuckle) Flower Extract (And) Approx up to <35% Water / Aqua Recommended Mandatory Ingredient Listing of INCI Name (Proposed) Specification Parameter Analysis Physical Form Colour Odour Specific Gravity (20deg.C) Refractive Index (20deg.C) pH(20°C) (100% Concentrate) Extraction Solvent Carbon Dioxide Gas Carrier Menstrual (Vehicle) Water Water Solubility Dry Residue (160deg.C/ 2hrs) Preservation Pesticide Content Total Germs Total Yeast/Mold Heavy Metals (Total) As, Pb, Hg Specification Range Results Methods Liquid Clear Colorless Yellowish Tint to Yellow Clear Ale Faint characteristics 1.120 - 1.320 1.300 - 1.450 8.00 – 12.00 See Batch lot COA Visual See Batch lot COA Visual See Batch lot COA See Batch lot COA See Batch lot COA See Batch lot COA Olifactory Paar, DMA35 DGF IV C (52) DGF H III (92) 3000 cc at 200-500 bar - - 30.0 - 57.0% Clearly hazy soluble 30- 70% None See Batch lot COA Soluble See Batch lot COA Conforms None Conforms Mettler 16J Pflanzaniaschuttal 1989 <100 Cfu/ml - NonPathogenic < 100 cfu/ ml < 0.005 ppm Conforms Ph.Eur.2.6.12 (97) Conforms Conforms Ph.Eur.2.6.12 (97) Ph.Eur2.6.12 (97) CAMPO Cosmetics S Pte. Ltd, SINGAPORE CAMPO RESEARCH USA, INC SAN DEIGO CA 92111, & Manhattan, New York City, USA CAMPO RESEARCH s.r.o., Brno, Czech Republic CAMPO RESEARCH Pvt. Ltd, CHENNAI, INDIA MATERIAL SAFETY & CONSUMER SAFETY TESTING LABS. DIV. OF JTC KAMPOYAKI SINGAPORE EMERGENCY MATERIAL SAFETY / ACCIDENTAL RELEASE CENTER Contact: Emergency Tel.no: +(65) 63833202 / 63833631(24hours) / 63228551 / 63228503 Emergency Fax No: +(65) 63834034 / 63833632 CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives MATERIAL SAFETY DATA SHEETS CONFIRMS TO EC DIRECTIVE 91/155/EEC, EC REGULATION NO#1272/2008, AMENDED EC REGULATION NO#790/2009 and to US DEPT.OF LABOROccupational Safety & Health Admin directives 1 DATE OF FIRST ISSUE February 10th 1992-Reviewer Dr Balasubramaniam PhD DATE OF LATEST REVISION Jan. 19th 1997- Rev’werDr Fergus Jes .G.Velasquez Bsc. Med Tech, MD th Mr Jimmy Kee, 30 June 2003 th Mr Teo SH 5 Jan 2004 st Balasubramaniam M,PhD 21 August 2007 Mr Joshua Teo, 21 Jan 2011 IDENTIFICATION COMMERCIAL NAME: CAMPO PLANTSERVATIVE WSr. Campo Product Number: 95-180-3004 PLANTWSr OTHER TRADE NAME: CTFA MONOGRAPH ID: LONICERA JAPONICA EXTRACT WATER SOLUBLE 8845 - Lonicera Caprifolium (Honeysuckle) Flower Extract 9690 - Lonicera Japonica (Honeysuckle) Flower Extract 9423 - Water / Aqua LATIN NAME: Lonicera Caprifolium flores extractum SYN LATIN NAME: INCI NAME: Lonicera japonica var.Caprifolium Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Lonicera Japonica (Honeysuckle) Flower Extract (And) Water / Aqua INCI NAME EU: Lonicera Caprifolium Extract (And) Lonicera Japonica Extract (And) Water / Aqua Lonicera Caprifolium (Honeysuckle) Flower Extract (And) Lonicera Japonica (Honeysuckle) Flower Extract (And) Water / Aqua INCI NAME (PROPOSED): JCID (Japan): INTERNATIONAL CHEMICAL IDENTIFICATION (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) EPA (USA) GENERIC NAME: MANUFACTURER: (cGMP MFG. FACILITIES) : 2 EMERGENCY TELEPHONE NUMBERS: COMPOSITION 100% CARBON-DIOXIDE EXTRACTED LONICERA JAPONICA FLOWER BUDS/FLORES AND LONICERA CAPRIFOLIUM FLOWER BUDS/FLORES EXTRACTED IN WATER CARRIER MENSTRUM CAS NO# (CAS Name): LONICERA CAPRIFOLIUM EXTRACT LONICERA JAPONICA EXTRACT AQUA (WATER) Japanese Honey Suckle Extract Campo Cosmetics (S) Pte Ltd Level 31, Sixth Battery Road Singapore 049909 (65)-63833631/(65)-62837781 (Singapore) Approx up to <20% Lonicera Japonica Var. Caprifolium Approx up to <45% (Lonicera caprifolium) Approx up to <35% (Water / Aqua) 84603-62-3 (Lonicera Caprifolium) 2237 49 799-9 (Lonicera Japonica) 773218-5 (Water / Aqua) CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives CAS NO# (CAS NAME) (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) 84603-62-3 (Lonicera Caprifolium) 2237 49 799-9 (Lonicera Japonica) 773218-5 (Water / Aqua) EINECS# & EINECS Name: 283-2636 (Lonicera Caprifolium) N/A (Lonicera Japonica Extract) 231-7912 (Water / Aqua) EINECS # (EINECS Name) (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) 283-2636 (Lonicera Caprifolium) N/A (Lonicera Japonica Extract) 231-7912 (Water / Aqua) EU INCI / EINECS FUNCTIONS BIOLOGICAL, ASTRINGENT, MASKING SKINCONDITIONING N/A Lonicera Carbon Dioxide & water-soluble esterified actives OTHER EU INCI / EINECS NAME 3 4 EINECS# EINECS# EINECS# EINECS# #N/A #N/A #N/A #N/A #N/A CHEM IUPAC NAME Lonicera Caprifolium Extract is an extract of the flowers of Honeysuckle, Lonicera Caprifolium, Caprifoliaceae. Lonicera Japonica Extract is an extract of the flowers of Honeysuckle, Lonicera Caprifolium, Caprifoliaceae. RISK PHRASES None SAFETY PHRASES 25-26 Not Mandatory HAZARDS NOT CLASSIFIED AS DANGEROUS ACCORDING TO DIRECTIVE 67/548/EEC OR ITS AMENDMENTS. HAZARD CLASS and CATEGORY CODE(s) HAZARD STATEMENT CODE(s) (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) FIRST AID MEASURES EYE CONTACT: ORAL INGESTATION: 5 SKIN CONTACT: FIRE FIGHTING MEASURERS NON-COMBUSTIBLE BUT PRESENTS NO SPECIAL FIRE HAZARD. EXTINGUISHING MEDIA: PROTECTIVE EQUIPMENTS FOR FIGHTERS: 6 7 Ester-Lonicerin Substance A Ester-Lonicerin Substance B Ester-Lonicerin Substance C Ester Lonicerin Substance D Lonicerin in Multi – Layered Complexes DIVISION 1.6; NON-HAZARDOUS NO HAZARD STATEMENT Wash with water or standard eye wash solution. Seek medical advice, if irritation occur and persist. Edible in small quantity (3-5 grams) with bland to bitter sweet after taste. Wash with water or shower. Treat as oil fire when store in HDPE drums with CO2, dry foam or dry chemical. Standard Equipments. ACCIDENTAL RELEASE MEASURES ABSORB ONTO AN INERT MATERIAL AND SCRAPE UP. REMOVE RESIDUE BY SCRUBBING WITH HOT WATER OR DETERGENT SOLUTION. HANDLING AND STORAGE CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives 8 9 STORE IN SEALED CONTAINERS UNDER NORMAL COOL, DRY WAREHOUSING CONDITIONS. EXPOSURE AND PERSONAL PROTECTION IN ACCORDANCE WITH GOOD INDUSTRIAL PRACTICE AND HANDLING USING STANDARD EYE PROTECTION. PHYSICAL AND CHEMICAL PROPERTIES PHYSICAL FORM: Liquid COLOUR: Clear Colorless Yellowish Tint to Yellow Clear Ale ODOUR: Faint characteristic BOILING POINT: 100C MELTING POINT: - VISCOSITY: - FLASH POINT: > 160C FLAMMABILITY SOLID/GAS: N/A AUTO FLAMMABILITY: N/A SPECIFIC REFRACTIVE: 1,300 – 1,450 EXPLOSIVE PROPERTIES: N/A pH: (100% Concentrate.) 8,00 – 12,00 OXIDIZING PROPERTIES: N/A VAPOUR PRESSURE: N/A DENSITY: 1,120 – 1,320 WATER SOLUBILITY: Soluble OTHER SOLUBILITY: In Most Cosmetic Solvents BULK DENSITY: - PARTITION COEFFICIENT: (OCTANOL/WATER) EXPLOSIVE LIMITS: INCOMPATIBILITIES: This material may be leaching in negligible trace amounts of Methylamine (Hexamine) and other Formol releasing (below Japan & EEC regulatory limits of Formaldehyde) hardening components of liquid resins of Epoxy and/or resins of phenolic of plastic molding process of plastic packaging. This material is incompatible with Schiff Reagents, and Assays Methods of Schiff Reaction, or Modified Schiff Reaction Assays, via Colorimetric Techniques or via HPLC COMPATIBLE ASSAYS 10 11 STABILITY AND REACTIVITY THERMAL DECOMPOSITION: TOXICOLOGICAL DATA ORAL: (Year 1992) DERMAL: Suggested Compatible Assay Methods “SPECTROPHOTOMETRIC METHOD AOAC OFFICIAL METHOD 931.08 & 964.21) as compatible ALTERNATIVE assays to any Assays of Schiff Reactions via Colorimetric or HPLC Stable under normal conditions of use. LD50 > 3,679 MG/KG (Body Wt.) Rat Essentially Non-Toxic and Edible in Small Quantity. Expected To Be Essentially Non Toxic. CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives INHALATION: N/A SPECIFIC CONCENTRATION LIMITS M-FACTORS (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) 3,679 MG/KG (Body Wt.); CATEGORY 5 Essentially Non-Toxic and Edible in Small Quantity TOXIC EFFECTS: SKIN: Primarily Irritation Index (PII) = 0.0 (Non- Irritating -Skintex), Not A Primarily Irritant. Non-irritant / Non-sensitizer as per Repeated Patch Insult Test on 50 Human volunteers. Human Repeated Patch Test 48 hours: 50/50 completely non-irritating / non-erythema causing ingredient at 5% concentrate in water on 50 human volunteers EYE: Very Mild/Minimal-not A Transient Conjunctival Irritant at 10% concentrate in water (Eyetex Classification). Summarized toxicological data as shown here are Information bounded under Non-Disclosure Agreement with various clients as when these Toxicological Data were established or/for their exclusive uses. 12 13 14 ECOLOGICAL INFORMATION BIODEGRATION: Expected to be ultimately Biodegradable FISH TOXICITY: No Data BACTERIAL & VIRAL TOXICITY: Potentially very harmful to bacterial & viral microorganisms. WGK CLASS: DISPOSAL CONDITIONS DISPOSE OFF ACCORDING TO A RECOGNISED METHOD OF CHEMICAL WASTE DISPOSAL. WGK (Self Classification) TRANSPORT INFORMATION UN NUMBER#: N/A UN NAME: Not Assigned IMDG CODE/CLASS: Not Hazardous IMDG CODE PAGE NO. N/A ICAO/IATA AIR CLASS: Non-Hazardous ICAO/IATA AIR CLASS PACKING 15 16 GROUP: N/A RID/ADR CLASS: Non-Hazardous ADNR CLASS: Non-Hazardous LABELLING: (EC REGULATION NO#1272/2008, AMENDED NO#790/2009) PICTOGRAM SIGNAL WORD CODE(s): HAZARD STATEMENT CODE(s): SUPPLEMENTARY HAZARD STATEMENT CODE(s): REGULATORY INFORMATION OCCUPATIONAL EXPOSURE LIMITS: OTHER INFORMATION No GHS Pictograms (Totally Non-Hazardous) Division 1.6; No Hazard Statement Similar Division 1.6; No Hazard Statement N/A CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives USES AS A COSMETIC ADDITIVE SUPPLEMENTARY DIETARY/FOOD USE. > 1.0 % 0.01 - 0.05 % (food preservation) Usage in Asia but is Not Recommended by Manufacturer for other territories outside Asia. Important Notice of Disclaimer Specifications may change without prior notice. Information contained in this technical literature Campo Plantservative WSr is believed to be accurate and is offered in good faith for the benefit of the customer. The company, however, cannot assume any liability or risk involved in the use of its natural products or their derivatives, since the conditions of use are beyond our control. Statements concerning the possible use are not intended as recommendations to use our products in the infringement of any patent. We make no warranty of any kind; expressed or implied, other than that the material conforms to the applicable standard specifications. This format and information is compiled by Kampoyaki Novel Natural Product Chemistry/ Novel Drug Discovery cGMP Labs Kobe, Japan; for Campo Research, Kyoto and Singapore. Contains No Synthetic PARABENS Recommended Mandatory Ingredient Listing of INCI Name: Lonicera Caprifolium (Honeysuckle) Flower Extract Lonicera Japonica (Honeysuckle) Flower Extract This is the composition / percentage of fresh succulent raw materials prior to extraction Approx up to <45% Lonicera Caprofolium (Honeysuckle) Flower Extract (And) Approx up to <20% Lonicera Japonica (Honeysuckle) Flower Extract (And) Approx up to <35% Water / Aqua CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC Campo Plantservatives DISCLAIMER: The information contained herein is accurate to the best knowledge and belief of Campo Cosmetics (S) Pte Ltd, and specification quoted may change without prior notice. Information contained in this technical literature is believed to be accurate and is offered in good faith for the benefit of the customer. The company, Campo Cosmetics (S) Pte Ltd, however, cannot assume any liabilities or risks involved in the use of its natural products or their derivatives or raw materials or ingredients, since the conditions of use are beyond Campo Cosmetics (S) Pte Ltd’ s control. Statements concerning the possible use are not intended as recommendations to use our materials in the infringement of any patents or infringements of mandatory regulatory requirements or without any safety evaluations conducted when used in combination with materials of other suppliers.. We make no warranty of any kind, expressed or implied, other than that the material conforms to the applicable standard specifications. Campo Cosmetics (S) Pte Ltd accepts no liabilities of whatsoever either expressed or as otherwise arising out of the information supplied, the application, adaptation or processing of the products described herein, or the use of other materials in lieu of the Campo materials or the use of Campo raw materials or ingredients in conjunction with any other products and raw materials. The use of Campo Cosmetics (S) Pte Ltd's raw materials or ingredients in any formulations are to be compulsory tested and to be assayed for safety and toxicology profiles evaluations and according the mandatory regulations as required by the laws and regulations of the countries where the evaluation and use of Campo Cosmetics (S) Pte Ltd's raw materials or ingredients has been formulated as single components in any carrier systems or as in multicomponents formularies. The end-users, marketers; manufacturers, formulation laboratories or importers of Campo Cosmetics (S) Pte Ltd' raw materials and ingredients which are incorporated into any formularies as formulated or re-sold or re-exported or assayed in accordance with any mandatory regulatory requirements of any country or infringement of any patents assume all liabilities as that may arise out of the use of Campo Cosmetics (S) Pte Ltd's raw materials and ingredients in any formularies in combination with raw materials and ingredients of other suppliers or as single components in any carriers. The definition of users as mentioned in these instances are manufacturers, marketers, formulation laboratories, consultants, and importers assumed all liabilities arising as either personal injuries suits, infringements of patents suits, infringements of or failures to meet regulatory requirements suits of a formulary either as single components in any carrier systems or in as multi-components formularies in which are may consist of a Campo Cosmetics (S) Pte Ltd's raw material or ingredients. CAMPO CD VERSION 3.6 dated 27 March 2012 © 2010 Library of Congress Wash.DC