Phonosurgery Symposium - Department of Surgery

www.surgery.wisc.edu/madison_voice_conference
Provided By
University of Wisconsin School of Medicine and Public Health
Department of Surgery, Division of Otolaryngology - Head & Neck Surgery
Office of Continuing Professional Development in Medicine and Public Health
Phonosurgery Symposium
14th Biennial
in conjunction with the
Modeling Laryngeal Biology
Fluno Center
Madison, Wisconsin
July 7-9, 2016
About the Conference
Course Highlights
The Modeling Laryngeal Biology conference is a one-day, state-of-the-art science course that will
consist of presentations and discussions pertaining to the application of In Vivo Animal Models,
In Vitro Animal Models, Ex Vivo Animal Models, Human Translation, and Computational Biology
Models to study the larynx. This conference will be held in conjunction with the 14th Biennial
Phonosurgery Symposium.
The 14th Biennial Phonosurgery Symposium is the only educational event in the region designed
for otolaryngologists, speech-language pathologists, and voice scientists. This course will provide
a pertinent update on modern clinical care and scientific research — basic and applied — of
the larynx and voice. Teaching formats include podium lectures, the ever-popular “hands-on”
workshops, and bring your own case.
Who Should Attend
This symposium is designed to assist practicing voice care professionals — otolaryngologists,
speech-language pathologists, voice teachers, voice professionals, and scientists — in
incorporating modern diagnostic and therapeutic strategies for voice care. Close interaction with
faculty is encouraged throughout all facets of the program to optimize learning.
Elements of Competence
This CME activity has been designed to change learner competence and focuses on the American
Board of Medical Specialties areas of patient care and procedural skills, and medical knowledge.
PLEASE NOTE: Educational credits are available for the Phonosurgery Symposium events on
July 8-9. Credits are not available for the Modeling Laryngeal Biology conference event on July 7.
The Fluno Center, on the University
of Wisconsin–Madison campus,
will host Modeling Laryngeal
Biology and the 14th Biennial
Phonosurgery Symposium.
University Hospital will host
on-site, hands-on workshops on
Saturday, July 9, the second day
of the 14th Biennial Phonosurgery
Symposium.
Learning Objectives
Modeling Laryngeal Biology (July 7) Learning Objectives
At the conclusion of this educational activity, participants should be able to …
• Recognize the gene/protein/tissue and functional deficits that define clinical need in our
populations of interest
• Understand the strengths and limitations of current experimental models available to laryngeal
biologists
• Explain scientific challenges associated with translation of clinically promising assessment and
treatment technologies
• Identify areas of greatest need in terms of model development, assay and outcome measures
development, and cell/tissue availability
14th Biennial Phonosurgery Symposium (July 8-9) Learning Objectives
At the conclusion of this educational activity, participants should be able to …
• Identify sources of new technologies for laryngology
• Define vocal influences of laryngeal inflammation
• Assess timing of surgical and behavioral treatment
• Recognize the role of surgery for the treatment of hoarseness
• Select appropriate treatment options — therapy versus surgery for neurological impairments of
the voice
• Compare approaches for surgical treatment of complex neurological voice disorders
• Review application of angiolytic laser therapy for voice disorders
• Define SLP treatment options of voice, cough, and airway disorders
Accreditation
Accreditation Statement
The University of Wisconsin School of Medicine and Public Health is accredited by the Accreditation
Council for Continuing Medical Education (ACCME) to provide continuing medical education for
physicians.
Credit Designation Statement
The University of Wisconsin School of Medicine and Public Health designates this live activity for a
maximum of 14 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate
with the extent of their participation in the activity.
Continuing Education Units
The University of Wisconsin-Madison, as a member of the University
Continuing Education Association (UCEA), authorizes this program for
1.4 continuing education units (CEUs) or 14 hours.
Conference Completion Report
You will be mailed a conference completion letter 3-4 weeks after the conference. To ensure
this process, please complete and submit the attendance verification form provided to you to
Nichole Rauch, [email protected], at the conclusion of the symposium.
Policy on Faculty and Sponsor Disclosure
It is the policy of the University of Wisconsin School of Medicine and Public Health that the faculty,
authors, planners, and other persons who may influence content of this CME activity disclose all
relevant financial relationships with commercial interests in order to allow CME staff to identify
and resolve any potential conflicts of interest. Faculty must also disclose any planned discussion of
unlabeled/unapproved uses of drugs or devices during their presentation(s). Detailed disclosures
will be made in the activity handout materials.
Agenda — Modeling Laryngeal Biology
Thursday July 7, 2016
AM
PLEASE NOTE: Educational credits are not
available for the Modeling Laryngeal Biology
conference event on July 7.
7:00Registration & Breakfast
7:55Welcome — Susan Thibeault & Nathan Welham
8:00 The Maxine Bennett, MD, Lecture
How Research in Laryngeal Biomechanics Can Benefit
Treatment of Unilateral Vocal Fold Paralysis
Sid Khosla, MD, is an associate professor of otolaryngology at the
University of Cincinnati College of Medicine and Director of the UC Health
Voice & Airway Center. He specializes in treating voice, airway, and
swallowing disorders and is nationally known for his expertise in vocal fold
and airway reconstruction. Dr. Khosla holds a BS in mechanical engineering
from MIT and an MS in biomechanics from UC San Diego under the
mentorship of YC Fung. Dr. Khosla currently splits his time between clinical
practice and research. As a member of the UC Health Performance &
Professional Voice Center, Khosla treats members of the local and national signing community
as well as lawyers, members of the clergy, politicians, professors, and teachers. Dr. Khosla’s
NIH-funded UC Laryngeal Biomechanics Lab studies the mechanisms of vocal fold vibration and
voice production under normal and abnormal conditions and after certain surgical procedures.
In Vitro Models
9:00In Vitro Experimental Models for the Study of Vocal Fold Scar and Presbyphonia —
Yo Kishimoto
9:15Anti-Fibrotic Effect of Pirfenidone on the Ferret Vocal Fold Scar In Vitro —
Yoshihiko Kumai
9:30In Vitro Culture of Vocal Fold Stellate Cells — Yutaka Toya
9:45Human Palatine Tonsil-Derived Mesenchymal Stem Cells as a Novel Source of Cells
Therapy for Vocal Fold Scarring — Byung-Joo Lee & Seong Hee Choi
10:00Developmental Derivation of Human Induced Pluripotent Stem Cell Vocal Fold Mucosa —
Vlasta Lungova
10:15Biomaterial Regulation of Cell Phenotype for Vocal Fold Scarring — Sarah Wang
10:30Refreshment Break & Exhibits
In Vivo Animal Models
10:45
Periaqueductal Gray: Genes Linked to Alpha-Synuclein Protein Breakdown Show Altered Expression in the PINK1 -/- Rat Model of Vocalization Dysfunction in Parkinson Disease — Cynthia Kelm-Nelson
11:15
Tissue-Engineered Vocal Fold Mucosa: Cell Persistence In Vivo — Jennifer Long
11:00
Modeling Dysregulated Laryngotracheal Wound Healing with an In Situ Mouse Model — Alexander Hillel
11:30Estrogen Effect on Extracellular Matrix Production of Vocal Fold in Rat —
Byung-Joo Lee & Seong Hee Choi
11:45
A Novel In Vivo Animal Model of Laryngeal Muscle Exercise Facilitates the Study of Laryngeal Muscle Plasticity — Timothy Butterfield
12:00
Chronic Neurostimulation for Treatment of Age Related Laryngeal Muscular Atrophy — Markus Gugatschka
PM
12:15
Lunch & Exhibits
Ex Vivo Animal Models
1:15
Sexual Dimorphism of Muscle Fiber Size and Type in the Adult Rat Thyroarytenoid — Charles Lenell
1:45
Perfusion-Decellularization of Dog Larynges — Kohei Nishimoto
1:30Ex Vivo High-Resolution MRI of the Porcine Larynx and Segmentation of Neurovascular Structures — Jonathan Wisco
2:00Refreshment Break & Exhibits
Computational Biology Models
2:15
Biosimulation of Vocal Fold Inflammation and Repair Using Agent-Based Modeling — Nuttiiya Seekhao
2:45
National Repository for Laryngeal Data — Eric Hunter
2:30
Computational Fluid Dynamics Analysis of Laryngeal Particle Deposition from Inhaled Corticosteroids — Guilherme Garcia & Jonathan Bock
3:00
Use of the Fiber-Gel Finite Element Model for Virtual Phonosurgery — Ingo Titze
Human Translation
3:15
Skeletal Muscle Bioenergetics: Implications for Voice Function — Mary Sandage
3:45
A Translational Prophylactic Model for Environmental Laryngeal Perturbation —
Kristine Tanner
3:30
4:00
4:15
4:30
Heightened Laryngeal Sensitivity During Voice and Speech: A Task-Specific Feature of Adductor Spasmodic Dysphonia? — Michael Hammer
Histologic and Morphometric Study of Paralyzed Recurrent Laryngeal Nerves —
Marshall Smith
Nerve Packaging and Aortic Arch Factors in the Onset of Idiopathic Unilateral Vocal Fold
Paralysis — Julie Barkmeier-Kraemer
The Great Debate — Susan Thibeault & Nathan Welham
5:30Closing
The annual Art Fair on the Square
will take place July 9-10 around
Madison’s Capitol Square. Nearly
500 artists from around the country
will exhibit paintings, prints,
sculpture, jewelry, and much more.
Agenda — Phonosurgery Symposium
Friday July 8, 2016
AM
6:00Registration & Breakfast
7:25Welcome — Timothy McCulloch, MD, FACS
Unified Airway
Moderator: Timothy McCulloch
7:30Health Reform 2.0: Beyond Healthcare — Jonathan Jaffery, MD
8:00Cost and Demographics of Dysphonia Care — David Francis, MD
8:15Catching Reflux with a Mouse — Nikki Johnston, PhD
8:30Treatment of Chronic Laryngitis — Stephanie Misono, MD, MPH
8:45Management of Chronic Cough from a SLP Perspective — Carol Tolejano, MA, CCC-SLP
9:00Refreshment Break & Exhibits
9:30Mucosal Immunology in the Development of Laryngotracheal Stenosis —
Alexander Hillel, MD
10:00Reflux Testing — Deepak Gopal, MD
10:15Laryngeal Mucus: The Good, The Bad, The Sticky — Elizabeth DiRenzo, PhD, CCC-SLP
10:30It’s Not Always Reflux: What Are We Missing? — Seth Cohen, MD, MPH
10:45 Paradoxical Vocal Fold Motion (PVFM) – Update on Differential Diagnosis and Treatment Efficacy — Mary Sandage, PhD, CCC-SLP
11:00
11:40
Panel discussion
Lunch & Exhibits
Phonosurgery
Moderator: Diane Bless
PM
12:40
The John Bascom Lecture
Innovations in Laryngeal Surgery
Steven M. Zeitels is the Eugene Casey Professor of Laryngeal Surgery at
Harvard and the director of the Massachusetts General Hospital Center
for Laryngeal Surgery. Zeitels is widely regarded as a prolific surgical
innovator having designed numerous new voice restoration procedures
(phonosurgery) and instruments, and has received five patents for these
innovations. He is acknowledged for pioneering novel laser applications to
treat laryngeal cancer dysplasia and papillomatosis as well as perfecting
office-based laryngeal laser surgery. He has received over 75 awards and
honored lectureships, authored more than 200 scientific articles, book chapters, and videos in
larynx and pharynx surgery, and presented over 300 papers and lectures. His work has been
widely discussed in the media, including the surgical and medical care of celebrity patients
including Adele, Julie Andrews, Steven Tyler (Aerosmith), Roger Daltrey (The Who), and Joe Buck.
1:25
1:40
Surgical Approaches to Reinke’s Space — Henry Hoffman, MD
Phonomicrosurgery for Benign Lesions — Frederik Dikkers, MD, PhD
1:55The Rolls of Post-op Voice Therapy — Debra Phyland, PhD
2:10Role of Infraglottic Medialization in Thyroplasty Type I — Sid Khosla, MD
2:25Voice Therapy for Benign Lesions — Ryan Branski, PhD, CCC-SLP
2:40Do’s and Don’ts for Treatment of Epitheial Disease — Peak Woo, MD, FACS, PLLC
2:55Refreshment Break & Exhibits
Neurolaryngology
Moderator: Seth Dailey
3:25
3:40
When Botox Stops Working — Gayle Woodson, MD
Laryngeal Rewiring for Spasmodic Dysphonia — Joel Blumin, MD, FACS
3:55Vocal Tremor Treatment: Factors that Matter — Julie Barkmeier-Kraemer, PhD, CCC-SLP
4:10Refining Surgical Management of Unilaterial Vocal Fold Paralysis —
Jennifer Long, MD, PhD
4:25
Type II Thyroplasty for Spasmodic Dysphonia — Tetsuji Sanuki, MD, PhD
4:55
Panel discussion
4:40
Science and Innovation for Thyroplasty — Jack Jiang, MD, PhD
5:30Adjourn
6:30Dinner at Steenbock’s on Orchard (Please see registration)
Saturday July 9, 2016
AM
6:00Registration & Breakfast
7:15Bus pick up at Fluno Center to University Hospital for Workshops, 8:00 am–1:50 pm.
See Workshops page for session times and bus schedule to and from Fluno Center.
PM
2:15Refreshment Break & Exhibits
How I Do It
Introduction: Charles Ford
2:45In Office Reflux Testing — Jonathan Bock, MD
3:00
3:15
Type I Thyroplasty: Pros and Cons of Three Techniques — Dale Ekbom, MD
Using Principles of the Semi-occluded Vocal Tract in Voice Therapy —
Joseph Stemple, PhD, CCC-SLP
3:30Incorporating Office Injections in Your Practice — Adam Klein, MD
BYOC
Introduction: Nathan Welham
4:00
Bring Your Own Case
5:00Closing
Workshops
Participants to the 14th Biennial Phonosurgery Symposium will have the chance to participate in a
number of hands-on workshops on Saturday, July 9. Each workshop will be offered multiple times,
and each participant can attend up to six different workshops. Online workshop registration is open
until June 27.
Scheduled Times
8:05 am – 8:45 am
8:55 am – 9:35 am
9:45 am – 10:25 am
10:35 am – 11:15 am
Lunch: 11:15 am – 11:45 am
11:55 am – 12:35 pm
12:45 pm – 1:25 pm
Bus Schedule
7:15 amBus pickup at Fluno Center to University
Hospital
1:50 pmBus pickup at University Hospital (Clinics
Entrance) to Fluno Center
Selected Workshops
Arytenoid Adduction & Abduction
Pediatric Voice Assessment
Assessment with High-Speed Laryngeal Imaging
Perioperative Voice Therapy
Balloon Dilation for the Airway
Pharyngoesophageal Manometry: Techniques &
Uses
Buccal Mucosa Graft
Phonomicrosurgery
Commercial Voice Rehabilitation from an Exercise Resonant and Airflow-Based Therapy Techniques:
Science Perspective
An Overview
CP Myotomy UIS
Shake It Off: Vocal Tremor Treatment
Crico Trachael Resection
Stroboscopy – Basic Principles & Practical
Guidance
Decision Making in Early Glottic Cancer
Surgical Techniques and Management of Pediatric
Voice and Airway Disorders
Diagnosis of Reflux
The De-RE Procedure for Spasmodic Dysphonia
Ex Vivo Teaching of Laryngeal Surgery
Transillumination Needle Localization for
Laryngeal Injection and MERS
Innovative Framework Surgical Approaches
Utilizing FEES in Everyday Clinical Practice
Laryngoplasty: How to Do It
Voice Care for Young Singers and Performers
** Workshops are subject to change
Things to Do in Madison
Art Fair on the Square — The 58th Annual Art
Fair on the Square will be held July 9-10 around
the Capitol Square, welcoming nearly 500 artists
from around the country. Each year, 200,000
visitors attend the outdoor event to take in art,
music, and food. www.mmoca.org/art-fair
Capitol Tour — Tour the Wisconsin Capitol on
your own or with a group.
www.tours.wisconsin.gov
Art Museums — Both the Madison Museum of
Contemporary Art and the Chazen Museum of
Art are within walking distance of the conference hotels. The Wisconsin Historical Museum
and the Wisconsin Veterans Museum are both
located on the Capitol Square. www.mmoca.
org, www.chazen.wisc.edu, www.wisconsin
history.org, www.wisvetsmuseum.com
Around Campus — The University of
Wisconsin–Madison campus is beautiful in the
summer. It’s home to dozens of attractions,
including the Geology Museum, Allen Centennial
Gardens, D.C. Smith Greenhouse, Babcock Hall
Dairy Store, and Wisconsin Institutes for Discovery. A visit to campus would be incomplete
without a stop at the Memorial Union Terrace on
Lake Mendota, a gathering place where campus
and community meet to enjoy the outdoors,
music, ice cream, and beverages. www.wisc.edu
Faculty
University of Wisconsin Faculty
Amy Baillies, MS, CCC-SLP, BCS-S
Molly Knigge, MS, CCC-SLP, BCS-S
Maia Braden, MS, CCC-SLP
Jamie Mayer, MS, CCC-SLP
Diane Bless, PhD, CCC-SLP **
Nadine Connor, PhD, CCC-SLP
Seth Dailey, MD **
Charles Ford, MD, FACS **
Deepak Gopal, MD
Jodi Hernandez, MS, CCC-SLP
Kathleen Huber, MS, CCC-SLP
Jonathan Jaffery, MD
Jack Jiang, MD, PhD
Stevie Marvin, MS, CCC-SLP
Katherine McConville, MA, CCC-SLP
Timothy McCulloch, MD, FACS **
J. Scott McMurray, MD, FAAP, FACS
Bryn Olson-Greb, MS, CCC-SLP
Brienne Ruel, MA, CCC-SLP
Susan Thibeault, PhD, CCC-SLP **
Carol Tolejano, MA, CCC-SLP
Nathan Welham, PhD, CCC-SLP **
** Planning Committee members
Visiting Faculty
Julie Barkmeier-Kraemer, PhD, CCC-SLP
University of Utah
Sid Khosla, MD
University of Cincinnati School of Medicine
Christopher Bingcang, MD
University of Nebraska-Omaha
Adam Klein, MD
Emory University
Joel Blumin, MD, FACS
Medical College of Wisconsin
Ying-Ta Lai, MD
Shuang Ho Hospital, Taipei Medical University
Jonathan Bock, MD
Medical College of Wisconsin
Jennifer Long, MD, PhD
UCLA
Ryan Branski, PhD, CCC-SLP
NYU School of Medicine
Stephanie Misono, MD, MPH
University of Minnesota
Seth Cohen, MD, MPH
Duke University
Debra Phyland, PhD
Voice Medicine Australia
Frederik Dikkers, MD, PhD
University Medical Center Groningen, Netherlands
Mary Sandage, PhD, CCC-SLP
Auburn University
Elizabeth E. DiRenzo, PhD, CCC-SLP
Stanford University School of Medicine
Tetsuji Sanuki, MD, PhD
Kumamoto University, Japan
Dale Ekbom, MD
Mayo Clinic
Joseph Stemple, PhD, CCC-SLP
University of Kentucky
David Francis, MD
Vanderbilt University
Kristine Tanner, PhD, CCC-SLP
Brigham Young University
Alexander Hillel, MD
Johns Hopkins University School of Medicine
Peak Woo, MD, FACS, PLLC
Mount Sinai School of Medicine
Henry Hoffman, MD
University of Iowa Hospitals and Clinics
Gayle Woodson, MD
Drexel University
Nikki Johnston, PhD
Medical College of Wisconsin
Steven Zeitels, MD
Center for Laryngeal Surgery, MGH
General Information
When:
Where:
July 7-9, 2016
Fluno Center for Executive Education
601 University Avenue
Madison, Wisconsin 53715
Phone: (877) 77-FLUNO/35866 or (608) 441-7117
Conference Fees
The conference fees are as follows:
Modeling Laryngeal Biology: $150 for all attendees
Phonosurgery Symposium: $495 for physicians, $325 for others
All three days: $600 for physicians, $400 for others, $150 for students
Fees include the cost of tuition, materials, continental breakfasts, breaks, lunches, and a
nonrefundable registration fee of $50. If you cancel your registration up to 72 hours prior to the
conference, you will be refunded the entire conference fee except the $50 nonrefundable portion of
the fee. No refunds will be granted within 72 hours of the conference. In addition, at the conclusion
of Friday’s scientific activities there will be an optional gathering with a reception and dinner at
Steenbock’s on Orchard in the Wisconsin Institutes for Discovery. Cost is $100.
Housing
A block of sleeping rooms has been reserved at the conference site, the Fluno Center ($149 per
night), in addition to rooms at the DoubleTree ($129 per night) and Graduate Madison ($159 per
night). Please write, call, or visit the hotel websites to arrange your accommodations. Please
reference group code PSS when making your reservation at the DoubleTree or Graduate Madison
and PHON at the Fluno Center to receive the special room rate, plus tax. The Fluno Center,
DoubleTree, and Graduate Madison will release rooms on June 6, 2016.
Four Easy Ways to Register (PREPAYMENT REQUIRED)
Mail:Return your completed registration form and payment to address listed
on the registration form. (Sign up for workshops at the conference.)
Phone:(608) 262-1397. Call and pay by VISA, MasterCard or American Express. (Sign up for
workshops at the conference.)
Fax:
(800) 741-7416 (in Madison 265-3163) (Sign up for workshops at the conference.)
Online: www.ocpd.wisc.edu/course_catalog (Sign up for workshops online.)
Confirmations
Registrations are confirmed via email. If you do not receive confirmation, call (608) 262-1397.
Conference Attire
Dress is business casual during the conference and Friday dinner. To ensure comfort in the
conference room, please bring a sweater or jacket to accommodate temperature variations.
For Further Information
Nichole Rauch
Program Coordinator
Division of OtolaryngologyHead & Neck Surgery
Department of Surgery
K4/723 Clinical Science Center
600 Highland Avenue
Madison, WI 53792-7375
(608) 263-0121
[email protected]
Christine Schmieden
Senior Public Affairs Specialist
Department of Surgery
H4/710 Clinical Science Center
600 Highland Avenue
Madison, WI 53792-7375
(608) 263-7697
[email protected]
Terese Bailey
OCPD in Medicine and
Public Health
750 Highland Avenue
Madison, WI 53705-2221
(608) 265-2046
[email protected]
Registration
#4033 ame-phon
Modeling Laryngeal Biology, July 7 &
14th Biennial Phonosurgery Symposium, July 8-9
Please complete Steps 1-3 in BLOCK letters.
Step 1. Participant Information:
Name _________________________________________________________________
FirstMI Last
Professional Degree (for name tag):
 MD
 DO
 PhD
 SLP
 Other, please specify ______________________
Company Name __________________________________________________________
Work Address ___________________________________________________________
City, State, Zip ___________________________________________________________
Daytime Phone ___________________________________________________________
Daytime Fax _____________________________________________________________
Email Address ___________________________________________________________
(please print clearly)
Special Needs? ___________________________________________________________
 Vegetarian Meals
Step 2. Registration Fees (check one, PREPAYMENT REQUIRED):
Modeling Laryngeal Biology, July 7:  $150 All Attendees
Phonosurgery Symposium & Workshops, July 8-9:  $495 MD, DO
All 3 Days, July 7-9:  $600 MD, DO
 $400 Others
 $325 Others
 $150 Students
Optional:  $100 Dinner on Friday Evening (seating is limited)
Choose one:  Chevre and Herb Stuffed Chicken Breast with Potatoes and Haricot Vert
 Braised Beef Short Rib with Crispy Parmesan Polenta Cake  Carrot Farro Risotto
 Check enclosed (payable to University of Wisconsin)
 Credit Card:  MasterCard  VISA  American Express
(We are not able to accept credit card payments at the event.)
Cardholder’s Name ________________________________________________________
Card Number ____________________________________________________________
Expiration Date ___________________________________________________________
Step 3. Send Your Registration Form and Payment To:
CME Specialist, Department 101, 702 Langdon Street, Madison, WI 53706
or FAX (800) 741-7416 (in Madison FAX 265-3163)
The University of Wisconsin provides equal opportunities in employment and programming, including Title IX requirement.
The University of Wisconsin School of Medicine and Public Health fully complies with the legal requirements of the ADA and
the rules and regulations thereof. If any participant in this educational activity is in need of special accommodations, please notify
Nichole Rauch at (608) 263-0121 in order to receive service.
www.surgery.wisc.edu
Remarkable People. Remarkable Results.
K4/723 Clinical Science Center
600 Highland Avenue
Madison, WI 53792-7375
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