Personality Pathology: Assessment and
Transcription
Personality Pathology: Assessment and
Personality Pathology: Assessment and prediction of change following group psychotherapy Sebastian Simonsen PhD Thesis Department of Psychology, Faculty of Social Sciences, University of Copenhagen ! %& %''( "# $ ) $ *%''(+ ! 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ypes of variance in genetic twin studies of personality: 1) Additive genetic variance: that proportion of phenotypic variance which is due to the addictive effect of genes (i.e., the summed effect of multiple genetic loci). Additive genetic effects can also be thought of as genetic effects passed directly from parents to offspring. This is indicated when the correlation for monozygotic twins is greater than that for the dizygotic twins because of the twofold greater similarity of monozygotic twins compared to dizygotic twins. 2) Nonadditive variance: that proportion of phenotypic variance which is due to dominance or epistatic interactions (the masking of the effects of a gene by one at a different locus, gene-gene interactions). This is indicated when the correlation is greater than twice the size of the correlation for dizygotic twins. 3) Shared environmental variance: that proportion of phenotypic variance which is due to the shared experiences of a twin pair e.g., social class. This is indicated by a low correlation of scores between dizygotic twin pairs. 4) Non-shared environmental variance: that proportion of phenotypic variance which is due to non-shared factors such as birth order. 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Socio-demographic and symptom characteristics of the clinical sample (N=76) Characteristics Clinical % Mean SD 36.3 11.0 49.6 5.5 1.7 .94 (N=76) Gender (female) 82.9 Age Education (highest level achieved) (N=67) Comprehensive school, only 30 30 9 13 + 2-3 years education 22 33 + 3-4 years education 13 19 3 4 40 60 High school + 5 years education (college) Living arrangement (N=67) Living with partner and children Living alone with children 8 12 11 16 8 12 2 3 0-6 months 40 60 >12 months 5 7 >24 months 9 13 Living alone Living with parents or others Work functioning (number of months since last working period) (N=67) Never worked (>20 hrs.) Previous psychiatric hospitalization (N=67) 29 43 Previous psychiatric treatment (N=67) 42 63 Receiving psychotropic drugs (N=67) 52 78 GAF (N=67) SCL-90-R (N=67) Somatization Obsessive-Compulsive 2.0 .78 Interpersonal Sensitivity 1.9 .81 Depression 2.4 .84 Anxiety 1.9 .90 Hostility 1.4 1.0 Phobic Anxiety 1.4 1.0 Paranoid Ideation 1.3 .93 Psychoticism 1.0 .70 GSI 1.8 .70 Note. GAF = Global Assessment Functioning; GSI = Global Severity Index Table 2. Diagnostic characteristics of the clinical sample (N=76) Diagnosis Clinical % (N=76) Axis I Diagnosis (N=64) Mood Disorders Major Depression Dysthymic Disorder 31 48 9 14 Anxiety Disorders Panic Without Agoraphobia 5 8 Panic With Agoraphobia 17 27 Social Phobia 19 30 Obsessive-Compulsive Disorder 4 6 Generalized Anxiety Disorder 8 13 Post Traumatic Disorder 5 8 Other Anxiety Disorders 13 20 Alcohol Dependence/Abuse 5 8 Drug Dependence/Abuse 4 6 Somatoform Disorders 10 16 Eating Disorders 11 17 Mean number of diagnoses 2.2 Substance Related Disorders Other Disorders Axis II Diagnosis (N=59) Schizotypal 1 2 Schizoid 0 0 Paranoid 4 7 Borderline 10 17 Antisocial 0 0 Narcissistic 1 2 Histrionic 0 0 Avoidant 25 42 Dependent 5 8 Obsessive-Compulsive 8 13 PD NOS (>5) 13 22 Depressive 10 17 5 8 11 19 Passive-Aggressive No PD Mean number of PDs Note. PD NOS = Personality Disorder Not Otherwise Specified 1.4 Table 3. Means, standard deviations and Coefficient alpha for the Danish DAPP-BQ scales Non-Clinical sample DAPP-BQ Clinical sample (N=76) M Total Non-Clinical sample (N=168) SD M SD Females (N=136) M Males (N=32) SD M SD Submissiveness 48.43*** 10.30 .86 33.78 7.25 .84 33.65 6.90 34.31 8.71 Cognitive Distortion 43.08*** 11.83 .89 26.52 7.05 .84 26.40 6.68 27.00 8.54 Identity Problems 50.75*** 12.78 .92 26.86 7.11 .87 25.71 6.85 26.50 8.20 Affective Instability 50.22*** 11.45 .88 34.52 8.83 .88 34.65 8.91 33.97 8.60 Stimulus Seeking 37.25 10.02 .85 35.07 7.40 .82 34.49 7.19 37.53* 7.89 Compulsivity 49.58*** 13.01 .92 45.18 8.07 .84 45.19 7.98 45.16 8.58 Restricted Expression 47.78*** 11.58 .88 31.98 6.66 .82 31.35 6.40 34.66* 7.16 Callousness 30.24*** 7.06 .76 26.43 5.83 .77 25.82 5.33 29.03* 7.10 Oppositionality 46.30*** 11.66 .88 31.95 8.34 .88 31.66 7.89 33.19 10.07 Intimacy Problems 34.58*** 9.79 .86 26.01 6.62 .82 26.10 6.82 25.59 5.82 Rejection 38.05 8.76 .80 38.02 6.96 .78 37.55 6.50 40.03 8.51 Anxiousness 55.38*** 12.49 .91 33.51 10.00 .92 33.38 9.56 34.09 11.84 Conduct Problems 28.47*** 9.66 .85 24.31 6.39 .80 23.51 5.97 27.69*** 7.12 Suspiciousness 34.08*** 11.73 .93 21.68 5.73 .86 21.40 5.40 22.88 6.94 Social Avoidance 49.78*** 12.67 .91 30.90 8.11 .88 30.63 7.68 32.03 9.80 Narcissism 43.29*** 11.22 .89 35.92 8.45 .87 35.10 7.96 39.41** 9.65 Insecure Attachment 46.28*** 14.33 .93 30.61 7.59 .85 30.53 7,48 30.94 8.19 Self-Harm 25.87*** 13.35 .94 13.56 3.57 .87 13.45 3.42 14.03 4.17 Note. DAPP-BQ = Dimensional Assessment of Personality Pathology-Basic Questionnaire p: Two-tailed probability levels associated with significant differences in means between females and males in the non-clinical sample *(p .05) ** (p .01) ***(p .001) Table 4. Oblimin-Rotated Principal Component structure Loadings* of the DAPP-BQ Clinical Sample (N=76) Dimension Non-Clinical Sample (N=168) ED DB IH CO ED DB IH CO Submissiveness 0.72 -0.12 0.35 0.12 0.86 0.34 0.14 0.17 Cogn. Distortion 0.80 0.37 0.13 -0.07 0.75 0.55 0.41 0.15 Identity Problems 0.88 0.21 0.30 -0.11 0.79 0.40 0.65 0.27 Affective Instability 0.82 0.48 -0.03 0.27 0.66 0.60 0.25 0.56 Stimulus Seeking 0.25 0.58 -0.43 -0.22 0.38 0.73 0.13 -0.09 Compulsivity 0.08 -0.16 0.14 0.90 0.17 0.06 0.08 0.89 Restr. Expression 0.31 -0.04 0.85 0.14 0.61 0.24 0.73 0.05 Callousness 0.13 0.81 -0.09 -0.19 0.37 0.78 0.41 -0.04 Oppositionality 0.72 0.27 -0.21 -0.50 0.80 0.46 0.31 -0.14 Intim. Problems 0.10 0.04 0.83 -0.07 0.26 0.23 0.90 0.10 Rejection 0.24 0.70 -0.30 0.38 0.31 0.81 0.03 0.34 Anxiousness 0.90 0.14 0.18 0.13 0.85 0.43 0.33 0.47 Cond. Problems 0.32 0.81 0.04 -0.14 0.36 0.72 0.24 -0.11 Suspiciousness 0.73 0.46 0.27 0.33 0.59 0.63 0.52 0.43 Social Avoidance 0.71 0.20 0.60 0.17 0.79 0.33 0.43 0.22 Narcissism 0.61 0.38 -0.12 0.17 0.69 0.67 0.04 0.33 Insec. Attachment 0.70 0.26 -0.18 0.13 0.60 0.53 0.05 0.40 % Accounted Variance 33.9 15.3 13.4 9.5 28.9 20.3 12.0 9.9 Note. DAPP-BQ = Dimensional Assessment of Personality Pathology-Basic Questionnaire; ED = Emotional Dysregulation; DB = Dissocial Behavior; IH = Inhibitedness; CO = Compulsivity *Highest and substantial loadings >0.40 are in boldface. Table 5. Zero-order correlation between DAPP-BQ Higher-Order Factor Scores and SCID-II personality disorder counts (number of fulfilled criteria) and scale scores of the Inventory of Interpersonal Problems-C Clinical sample ED DB IH CO Paranoid 0.49*** 0.29* 0.27* 0.05 Schizotypal 0.38** 0.32* 0.01 -0.21 Schizoid 0.10 0.15 0.25 0.06 Antisocial 0.25 0.42*** 0.01 -0.08 SCID-II (N=59) Borderline 0.57*** 0.41*** 0.11 -0.26* Histrionic 0.16 0.13 0.02 -0.02 Narcissistic 0.26* 0.22 -0.14 -0.13 Dependent 0.50*** 0.08 0.23 -0.18 Avoidant 0.55*** 0.17 0.34** 0.08 Compulsive 0.12 0.17 0.18 0.45*** PD-total score 0.67*** 0.43*** 0.23 -0.06 Dominering 0.51*** 0.58*** -0.05 -0.12 Vindictive 0.50*** 0.40** 0.20 -0.13 Cold 0.46*** 0.29* 0.57*** 0.03 IIP-C(N = 59) Socially Avoidant 0.54*** 0.11 0.62*** 0.08 Nonassertive 0.43*** -0.12 0.45*** 0.05 Exploitable 0.27* -0.39** 0.47*** 0.04 Overly Nurturant 0.25 -0.28* 0.42*** 0.13 Intrusive 0.29* 0.20 0.09 -0.11 Note. 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"4 &,2J 5- *,20,+4 2 +2 00.0(- E "B " J "4 )- ; -" )- +.6 4 #- *%''0+-E J "B 2 +72 ,,'.,&'- "4 - ? - 5- K- " P - *,22(+- . -, 4 2 '72 10.(/J )- K- - : )- E- " ? - *,222+- K . . -4 2 )%2 ,&%7.,&&'J -" $ G - *,212+- - B & 2 +%2 ,00.,10S :- - *,220+- " - *0 -+ F S $ 6 6 $ - Table 1. Five-factor model: NEUROTICISM Study Evidence Level Main diagnoses Treatment type & (N) Effect size Trait and effect on outcome in Group Therapy Ogrodniczuk et al., 2003 A2 Major depression and personality disorder IGP & SGP (91) .30 Neuroticism (high) (NEO-FFI) predicted less improvement in general symptoms in both IGP and SGP. Association corrected for baseline severity. Zettle et al., (1992) & 1995 B Dysthymia IBT and GCBT (25) p values Neuroticism (high sociotropy) (SAS) did not predict more improvement in post depression symptoms for patients matched to either GCBT or IBT. Association corrected for baseline severity. Talbot et al., 2003 B Affective disorders (sexually abused) WSIR in addition to TAU-PHP (43) Not reported Neuroticism (NEO-FFI) was neither related to improvement in general symptoms in WSIR in addition to TAU or in TAU alone. Association corrected for baseline severity. Spek et al., 2008 B Sub-threshold depression GCBT and INBT (111) .25 Neuroticism (high) (NEO-FFI) Predicted less improvement in depression symptoms in both GCBT and IBT. Association corrected for baseline severity. Steinmetz et al., 1983 C Unipolar depression PEGT (70) Not reported Neuroticism (EPQ) was not related to improvement in depression symptoms in PEGT. Association corrected for baseline severity. Fisher et al., 1993 C Major depression SGT for sexual abuse (55) .05-.21 Neuroticism (avoidant, passive-aggressive, schizotypal and borderline traits) (MCMI) were not related to dropout in SGT for sexual abuse. Enns et al., 2002 C Major depression GCBT (65) .24 Neuroticism (high) (self criticism) (DEQ) predicted less improvement in depression symptoms in GCBT. Association corrected for baseline severity. Saulsman et al., 2006 C Major depression and personality disorder GCBT (117) .12 Neuroticism (depressive personality traits) (MCMI-III) was not related to improvement in depression scores for GCBT. Association corrected for baseline severity Tasca et al., 2006 A2 Binge eating disorder GCBT and GPIP (66) -.36 & .48 Neuroticism (high attachment anxiety) (ASQ) was related to more improvement in days binging in GPIP and less improvement in days binging in GCBT. Conversely low attachment anxiety was related to more improvement in days binging in GCBT and less improvement in GPIP. Association corrected for baseline severity. Mörtberg et al., 2007 B Social phobia and personality disorder IGCT (59) .31 Neuroticism (high harm avoidance) (TCI) predicted less improvement in social anxiety in IGCT. Association corrected for baseline severity. Clair et al., 1992 C Agoraphobia GCBT (30) .12 Neuroticism (MPI) was not related to improvement in phobia in GCBT. Association corrected for baseline severity Chambless & Tran, 1997 C Social phobia GCBT (59) .25 Neuroticism (high scores on avoidant traits) (MCMI) predicted less improvement in anxiety symptoms in GCBT. Association corrected for baseline severity. Brown et al., 1998 C Social phobia GCBT (28) Not reported Neuroticism (autonomy/ sociotropy) (PSI) was not related to improvement in anxiety in GCBT. Erwin et al., 2003 C Social phobia GCBT (68) .14-.39 Neuroticism (high trait anger/temperament/anger-in) (STAXI) related to less improvement in anxiety and depression symptoms in GCBT. Associations corrected for baseline severity. Tasca et al., 2004 C Anorexia nervosa PHP (74) .53 Neuroticism (highly preoccupied) (ASQ) predicted treatment completion (though only for binge-purge subtype not for restricting subtype) in PHP group-based. Franzen et al., 2004 C Eating disorders PHP (125) p values Neuroticism (high aggressiveness) (FPI-R) predicted non-completion in PHP. AFFECTIVE DISORDERS OTHER DISORDERS Notes: Treatment type abbreviations: (IGP) Interpretive Group Psychotherapy, (SGP) Supportive Group Psychotherapy, (IBT) Individual Behavioural Therapy, (GCBT) Group Cognitive Behavioural Therapy, (WSIR) Womens Safety in Recovery group), (TAU) Treatment As Usual, (PHP) Partial Hospitalization Programme, (INBT) Internet-based Treatment, (PEGT) Psychoeducational Group Treatment, (GPIP) Group Psychodynamic Interpersonal Psychotherapy, (IGCT) Intensive Group Cognitive Therapy.. Measure abbreviations: (NEOFFI) NEO-Five-Factor Inventory, (SAS) Sociotropy-Autonomy Scale, (EPQ) Eysenck Personality Inventory, (MCMI) Millon Clinical Multiaxial Inventory, (DEQ) Depressive Experience Questionnaire, (ASQ) Attachment Styles Questionnaire, (TCI) Temperament and Character Inventory, (MPI) Maudsley Personality Inventory, (PSI) Personal Style Inventory, (STAXI) The State-Trait Anger Expression Inventory, (FPI-R) Freiburger Personality Inventory – Revised Form- Table 2. Five-factor model: EXTRAVERSION Study Evidence Level Main diagnoses Treatment type & (N) Effect size Trait and effect on outcome in Group Therapy Ogrodniczuk et al., 2003 A2 Major depression and personality disorder IGP & SGP (91) .37 Extraversion (high) (NEO-FFI) predicted more improvement in general symptoms in both SGP and IGP. Association corrected for baseline severity. Beutler et al., 1991 B Major Depression GCBT (63) GFEP IS/SD .17 & .48 vs. -.60 Extraversion (high) (Low resistance potential) (MMPI) predicted more improvement in depression symptoms in GCBT and GFEP than in IS/SD. Conversely patients with high resistance potential (Low E) responded better to IS/SD than to both GCBT and GFEP. Association corrected for baseline severity. Talbot et al., 2003 B Affective disorders (sexually abused) WSIR in addition to TAUPHP or TAU-PHP alone (43) AFFECTIVE DISORDERS .31 vs. -.20 Extraversion (low) (NEO-FFI) predicted more improvement in general symptoms in WSIR in addition to TAU but not in TAU alone. Association corrected for baseline severity. Spek et al., 2008 B Sub-threshold depression GCBT and INBT (111) .05 Extraversion (NEO-FFI) was not related to improvement in depression symptoms in either GCBT or INBT. Steinmetz et al., 1983 C Unipolar depression PEGT (70) Not reported Extraversion (EPQ) was not related to improvement in PEGT. Fisher et al., 1993 C Major depression SGT for sexual abuse (55) .34 Extraversion (high) (Low scores on dependent traits) (MCMI) predicted non-completion in SGT. Potvin et al., 2000 C Mood disorders and personality disorder PHP (224) .21 Extraversion (low) (Social introversion) (MMPI) predicted less improvement in general symptoms in group-based PHP. Association corrected for baseline severity. Lorentzen & Høglend, 2004 C Affective disorders and personality disorder LAGP (40) .49 Extraversion (high) (Intrusiveness) (IIP) scores predicted more improvement in interpersonal problems in LAGP. Association corrected for baseline severity. Tasca et al., 2006 A2 Binge eating disorder GCBT and GPIP (95) .47 Extraversion (low) (Higher attachment avoidance) (ASQ) was related to dropping out in GCBT but not in GPIP. Mörtberg et al., 2007 B Social phobia and personality disorder IGCT (59) .31 Extraversion (low) (high harm avoidance) (TCI) predicted less improvement in social anxiety in IGCT. Association corrected for baseline severity. Clair et al., 1992 C Agoraphobia GCBT (30) -.23 Extraversion (MPI) was not related to improvement in fear symptoms in GCBT. Chambless & Tran, 1997 C Social Phobia GCBT (59) .25 Extraversion (low) (High scores on Avoidant traits) (MCMI) predicted less improvement in anxiety symptoms in GCBT. Association corrected for baseline severity. Franzen et al., 2004 C Eating disorders PHP (125) p values Extraversion (high) (Low Inhibitedness and high Extraversion) (FPI-R) predicted non-completion in PHP. OTHER DISORDERS Notes: Treatment type abbreviations: (IGP) Interpretive Group Psychotherapy, (SGP) Supportive Group Psychotherapy, (IBT) Individual Behavioural Therapy, (GCBT) Group Cognitive Behavioural Therapy, (WSIR) Womens Safety in Recovery group), (TAU) Treatment As Usual, (PHP) Partial Hospitalization Programme, (INBT) Internet-based Treatment, (PEGT) Psychoeducational Group Treatment, (GPIP) Group Psychodynamic Interpersonal Psychotherapy, (IGCT) Intensive Group Cognitive Therapy, (GFEP) Group Focused Expressive Psychotherapy, (IS/SD) Individual Supportive/Self-directed therapy, (SGT) Specialized Group Therapy, (LAGP) Long-term Analytic Group Psychotherapy, (GPST) Group Psychotherapy Short-term, (IPGP) Intensive Psychodynamic Group Psychotherapy. Measure abbreviations: (NEO-FFI) NEO-Five-Factor Inventory, (MMPI) Minnesota Multiphasic Personality Inventory, (EPQ) Eysenck Personality Inventory, (MCMI) Millon Clinical Multiaxial Inventory, (IIP) Inventory of Interpersonal Problems, (ASQ) Attachment Styles Questionnaire, (TCI) Temperament and Character Inventory, (MPI) Maudsley Personality Inventory,(FPI-R) Freiburger Personality Inventory – Revised Form. Table 3. Five-factor model: OPENNESS Study Evidence Level Main diagnoses Treatment type & (N) Effect size Trait and effect on outcome in Group Therapy McCallum & Piper, 1990 A2 Affective disorders and personality disorder GPST (54) .57 Openness (low) (low psychological mindedness) (PMAP) strongly related to dropout but not to improvement in GPST. Association not corrected for baseline severity. Piper et al., 1994 A2 Major depression and personality disorder PHP (59) .33 Openness (high) (high psychological mindedness) (PMAP) predicted more improvement in general symptoms in PHP, but was not related to dropout. Association corrected for baseline severity. Ogrodniczuk et al., 2003 A2 Major depression and personality disorder IGP & SGP (101) .22 Openness (high) (NEO-FFI) predicted more improvement in target objectives and life satisfaction (but not general symptoms) in both SGP and IGP. Association corrected for baseline severity. McCallum et al., 2003 A2 Major depression and personality disorder IGP & SGP (107) .32 Openness (low) (high Alexithymia) (TAS-20) was related to less improvement in general symptoms in SGP. Association corrected for baseline severity. Beutler et al., 1991 B Major Depression GCBT GFEP IS/SD (63) .17 & .48 vs. .60 Extraversion (high) (Low resistance potential) (MMPI) predicted more improvement in depression symptoms in GCBT and GFEP than in IS/SD. Conversely patients with high resistance potential (Low E) responded better to IS/SD than to both GCBT and GFEP. Association corrected for baseline severity. Talbot et al., 2003 B Affective disorders (sexually abused) WSIR in addition to TAU PHP or TAU alone (43) Not reported Openness (NEO-FFI) was not related to improvement in general symptoms in either WSIR in addition to TAU or in TAU alone. Spek et al., 2008 B Subthreshold depression GCBT and INBT (111) .00 Openness (NEO-FFI) was not related too improvement in depressive symptoms in either GCBT or INBT. Association corrected for baseline severity. Yalom et al., 1967 C Neurotic and character disorders IPGP (40) Not reported Openness (Psychological mindedness) (CPI) was not related to improvement in symptoms in IPGP. Caine & Wijesinghe, 1976 C Neurotic and character disorders GP or IBT (24) p values Openness (high) (More Internally directed interest and Low Conservatism) (DIQ) (the Conservatism Scale) are more responsive to GP. Partially corrected for baseline severity. Pearson et al., 1990 C Primarily neurotic and personality disorders PGT (32) - .02-.31 Openness (Internally directed interest and Conservatism (DIQ) (the Conservatism Scale) were not related to improvement in general symptoms in PGT. Association corrected for baseline severity McCallum et al., 1997 C Major depression and personality disorder PHP (142) Not reported Openness (Psychological mindedness) (PMAP) was neither related to outcome or dropout in PHP. Tasca et al., 1999 C Major depression and personality disorder PHP (102) .34 Openness (low) (low psychological mindedness) (PMAP) predicted non-completion in PHP. Potvin et al., 2000 C Mood disorders and personality disorder PHP (224) Not reported Openness (low) (Psychopathic deviation & Paranoia) (MMPI/MMPI-2) was not related to improvement in general symptoms in PHP AFFECTIVE DISORDERS Notes: Treatment type abbreviations: (GPST) Group Psychotherapy Short-term, (PHP) Partial Hospitalization Programme (IGP) Interpretive Group Psychotherapy, (SGP) Supportive Group Psychotherapy, (GCBT) Group Cognitive Behavioural Therapy, (GFEP) Group Focused Expressive Psychotherapy, (IS/SD) Individual Supportive/Self-directed therapy (WSIR) Womens Safety in Recovery group), (TAU) Treatment As Usual, , (INBT) Internet-based Treatment, , (IPGP) Intensive Psychodynamic Group Psychotherapy, (GP) Group Psychotherapy, (IBT) Individual Behavioural Therapy (PGT) Psychodynamic Group therapy. Measure abbreviations: (PMAP) Psychological Mindedness Assessment procedure, (NEO-FFI) NEO-Five-Factor Inventory, (TAS-20) 20-item Toronto Alexithymia Scale, (MMPI) Minnesota Multiphasic Personality Inventory, (CPI) California Personality Inventory, (DIQ) Direction of Interest Questionnaire. Table 4: Five-factor model: AGREEABLENESS Study Evidence Level Main diagnoses Treatment type & (N) Ogrodniczuk et al., 2003 A2 Major depression and personality disorder IGP & SGP (88) Mohr et al., 1990 B Major depression Beutler et al., 1991 B Major depression Zettle et al., (1992) & 1995 B Dysthymia GCBT GFEP IS/SD (62) GCBT GFEP IS/SD (63) IBT and GCBT (25) Talbot et al., 2003 B Affective disorders (sexually abused) Spek et al., 2008 B Nash et al., 1957 Effect size -.36 vs. .13 AFFECTIVE DISORDERS Agreeableness (high) (NEO-FFI) was related to more improvement in grief symptoms in IGP but not in SGP. Association corrected for baseline severity. .56 Agreeableness (low) (high Level of Interpersonal problems) (IIP) was related to both more and to less improvement in depressive symptoms in all types of treatment. Non- and negative response groups characterised as more externalizing. Association corrected for baseline severity. -.57 vs. .53 & -.20 Agreeableness (low) (Higher Externalizing) (MMPI) predicted more improvement in depressive symptoms in GCBT than in either IS/SD or GFEP. Conversely nonexternalizing patients did worse in GCBT and significantly better in IS/SD. Level of externalization had little impact in GFEP. Association corrected for baseline severity. Agreeableness (high sociotropy) (SAS) did not predict more improvement in depression symptoms for patients matched to either GCBT or IBT. Association corrected for baseline severity. Agreeableness (low) (NEO-FFI) was related to more improvement in general symptoms in WSIR in addition to TAU, but not in TAU alone. Association corrected for baseline severity. p values Subthreshold depression WSIR in addition to TAU PHP or TAU alone (43) GCBT and INBT (111) .08 C Psychiatric outpatients AGP (24) p values Budman et al., 1980 C Psychiatric outpatients PGT (81) p values Fisher et al., 1993 C Major depression .30-.36 Davies-Osterkamp et al., 1996 Rice, 2003 C p values C GCBT (42) .39 Lorentzen & Høglend, 2004 C Neuroses and personality disorders Major depression and personality disorder Affective disorders and personality disorder SGT for sexual abuse (55) PAGT (194) LAGP (40) -.40 & -.33 Alden & Capreol, 1993 A2 GEG, STG, IFSTG, WL (76) Mörtberg et al., 2007 B .30, .45, .47 vs. .28 Not reported Avoidant personality disorder Trait and effect on outcome in Group Therapy .58 vs. -.15 Agreeableness (high altruism) (NEO-FFI)) was related to more improvement in depressive symptoms in GCBT than in INBT. Association corrected for baseline severity. Agreeableness (low) (Social ineffectiveness) (the Social Ineffectiveness Scale)) was related to dropping out of AGP. Patient with high social ineffectiveness only remained in group therapy if subjective discomfort was high. No correction for baseline severity Agreeableness (high) (Closeness) (Personal Assessment) to others was related to more improvement in major problems in PGT. No correction for baseline severity Agreeableness (low) (Higher Narcissistic, antisocial and paranoid traits) (MCMI) was related to dropout in SGT for sexual abuse. Association corrected for baseline severity. Agreeableness (low) (higher level of Interpersonal problems) (IIP) was related to more improvement in general symptoms in PAGT. No correction for baseline severity. Agreeableness (high) (High Need for social approval) (IIP) was related to improvement in self-esteem in GCBT. Association corrected for baseline severity. Agreeableness (high and low) (high Overly nurturant and coldness scores) (IIP) were related to less improvement in general symptoms and interpersonal problems in LAGP. Association corrected for baseline severity. OTHER DISORDERS Agreeableness (exploitable-avoidant vs. cold-avoidant) (IIP). Exploitable-avoidant (high A) patients improved more in anxiety and other symptoms than WL with all three types of treatment. Cold-avoidant patients (low A) improved more in anxiety and other symptoms with GEG than with WL, STG or IFSTG. Associations corrected for baseline severity. Agreeableness (Cooperativeness) (TCI) was not related to improvement in IGCT Social phobia and personality IGCT (59) disorder Clair et a., 1992/C C Agoraphobia GCBT (30) -.11-.41 Agreeableness (interpersonal problems scales) (FIRO-B) was not related to improvement in fear symptoms in GCBT Chambless & Tran, 1997 C Social phobia GCBT (59) .09 Agreeableness (dependent traits) (MCMI) was not related to improvement in anxiety symptoms in GCBT. Association corrected for baseline severity. Brown et al., 1998/C C Social phobia GCBT (45) Not reported Agreeableness (sociotropy & autonomy) (PSI) were not related to improvement in GCBT Notes: Treatment type abbreviations: (IGP) Interpretive Group Psychotherapy, (SGP) Supportive Group Psychotherapy, (GCBT) Group Cognitive Behavioural Therapy, (GFEP) Group Focused Expressive Psychotherapy, (IS/SD) Individual Supportive/Self-directed therapy, (IBT) Individual Behavioural Therapy, (WSIR) Womens Safety in Recovery group), (TAU) Treatment As Usual, (PHP) Partial Hospitalization Programme, (INBT) Internet-based Treatment, (AGP) Analytic Group psychotherapy, (PGT) Psychodynamic Group therapy, (SGT) Specialized Group Therapy, WL (Waiting list) (PAGT) Psychoanalytic Group Psychotherapy, (LAGP) Long-term Analytic Group Psychotherapy, (GEG) Graduated Exposure Group, (STG) Skills Training Group, (IFSTG) Intimacy Focused Skills Training Group, (IGCT) Intensive Group Cognitive Therapy. Measure abbreviations: (NEO-FFI) NEO-Five-Factor Inventory, (IIP) Inventory of Interpersonal Problems, (SAS) Sociotropy-Autonomy Scale, (MMPI) Minnesota Multiphasic Personality Inventory, (MCMI) Millon Clinical Multiaxial Inventory, (TCI) Temperament and Character Inventory, (FIRO-B) Fundamental Interpersonal Relations Orientation Behaviour Scale, (PSI) Personal Style Inventory. Table 5: Five-factor model: CONSCIENTIOUSNESS Study Evidence Level Main diagnoses Treatment type & (N) Effect size Ogrodniczuk et al., 2003 A2 IGP & SGP (90) .29 Zettle et al.,(1992) & 1995 B Major depression and personality disorder Dysthymia Talbot et al., 2003 B Spek et al., 2008 B Affective disorders (sexually abused) Subthreshold depression WSIR in addition to TAU PHP or TAU alone (43) GCBT and INBT (111) Steinmetz et al., 1983 C Unipolar depression PEGT (70) .14 Hoberman et al., 1988 C Unipolarpolar depression PEGT (63) .22 Fisher et al., 1993 Hazzard et al., 1993 C C Major depression Psychiatric outpatients SGT for sexual abuse (55) POGT (49) .22 .01 Mörtberg et al., 2007 B IGCT (59) Not reported Bowen et al., 1994 C GCPT (48) -.53 Chambless & Tran, 1997 Franzen et al., 2004 C C Social phobia and personality disorder Panic disorder and agoraphobia Social phobia Eating disorders GCBT (59) PHP (125) -.07 p values IBT and GCBT (25) Trait and effect on outcome in Group Therapy AFFECTIVE DISORDERS Conscientiousness (NEO-FFI) was related to more improvement in general symptoms in both IGP and SGP. Association corrected for baseline severity. p values Conscientiousness (High Autonomy) (SAS) did not predict more improvement in depression symptoms for patients matched to either GCBT or IBT. Association corrected for baseline severity. Not reported Conscientiousness (NEO-FFI) was not related to improvement in general symptoms in either WSIR in addition to TAU-PHP or in TAU alone .11 Conscientiousness (NEO-FFI) was not related to improvement in depressive symptoms in either GCBT or in IBT. Association corrected for baseline severity Conscientiousness (higher) (Perceived Mastery of control) (items) was associated with more improvement in depressive symptoms in PEGT. Locus of control (Social Reaction Inventory) was not associated with improvement in depressive symptoms in PEGT. Associations corrected for baseline severity. Conscientiousness (Perceived mastery) (Mastery Scale) was related to more improvement in depressive symptoms in PEGT. Association corrected for baseline severity. Conscientiousness (Compulsive traits) (MCMI) was not related to dropout in SGT for sexual abuse Conscientiousness (Locus of control) (Locus of control scale) was not related to improvement in general symptoms in POGT OTHER DISORDERS Conscientiousness (Persistence) (TCI) was not related to improvement in social anxiety in IGCT. Conscientiousness (Sense of mastery) (Pearlin Mastery Scale) was related to more improvement in anxiety and other symptoms in GCBT. Association corrected for baseline severity. Conscientiousness (Compulsive traits) (MCMI) was not related to improvement in anxiety symptoms in GCBT. Conscientiousness (Achievement orientation) (FPI-R) was not related to non-completion in PHP Notes: Treatment type abbreviations: (IGP) Interpretive Group Psychotherapy, (SGP) Supportive Group Psychotherapy, (IBT) Individual Behavioural Therapy, (GCBT) Group Cognitive Behavioural Therapy, (WSIR) Womens Safety in Recovery group), (TAU) Treatment As Usual, (PHP) Partial Hospitalization Programme, (INBT) Internet-based Treatment, (PEGT) Psychoeducational Group Treatment, (SGT) Specialized Group Therapy, (POGT) Process-oriented Group Psychotherapy. (IGCT) Intensive Group Cognitive Therapy. Measure abbreviations: (NEO-FFI) NEO-Five-Factor Inventory, (SAS) Sociotropy-Autonomy Scale, (MCMI) Millon Clinical Multiaxial Inventory, (TCI) Temperament and Character Inventory, (FPI-R) Freiburger Personality Inventory – Revised Form.