Newsletter Fall 2012

Transcription

IBB
Integrative Biosciences & Biotechnology
Newsletter Fall 2012
01
Division News
n
n
n
n
n
n
n
n
07
Campus Talk
n
n
n
12
Accomplishments
n
n
Division held 2012 IBB Workshop from Mar. 5 to 6, 2012 at POSTECH Biotech Center
New graduate students welcome party was held on Mar. 5, 2012 at POSCO International Center
The First Symposium of the Institute for Basic Science in 2012 was held in April 27
POSTECH graduate program information session was held in May 13, 2012 at the POSCO Center in Seoul
Immune Homeostasis & Regulation R&D Group (IHRRG) Symposium held from Jun. 14 to 15, 2012 in Gyeongju
Joint symposium of Seoul St. Mary’s Hosp CRCiD, POSTECH IBB and Jilin Univ. IIJU was held at Catholic University
on Jun. 18, 2012
2012 Summer IBB internship program held from July 2 to 27, 2012 for 4 weeks
Evening Festival for Bio-members at POSTECH was held on Jul. 12, 2012 at POSTECH Biotech Center
Expand your horizon by interacting each other/ written by Professor Ki-Hean Kim
Looking Back Through Time : My First Year / written by Hee-Young Yoo
IBB Laboratory Tour : T cell Biology Laboratory
Faculty : Appointment / Publications
Graduate students : Award & Honors
Division News
Division held 2012 IBB Workshop from Mar. 5 to
6, 2012 at POSTECH Biotech Center
Together with all IBB members
Division held 2012 IBB Workshop for 2 days from March 5 to 6, 2012 at
POSTECH Biotech Center. Twenty faculty members in the division attended
the workshop as speakers, and about 60 IBB graduate students and
researchers attended the workshop.
The workshop started with an opening remark by division chairman, professor Inhwan Hwang, after that, with the start of presentations of newly join
professors Yongwon Choi and Seung-Woo Lee, each IBB professor presented
their research interests and current research information to the attendance
at the workshop. After presented, it was followed by question and answer
session.
The purpose of the workshop is to assemble all IBB members of professors
and students in a place at POSTECH to exchange current research information and find a way to develop joint researches between the laboratories.
This was the third IBB workshop held by division since 2009, and division is
planning to hold 2013 IBB workshop at the beginning of spring semester in
2013.
01
IBB POSTECH NEWSLETTER Fall 2012
1. Opening remarks
by Chair of IBB, Prof. Inhwan Hwang
2. Presentation at the workshop
3. 2012 IBB Workshop programs
Division News
New graduate students welcome party was held
on Mar. 5, 2012 at POSCO International Center
Dinner with IBB professors and students
At the beginning of the 2012 spring semester, we invited division professors
and graduate students for the welcome party of 2012 IBB new graduate
students at POSCO International Center on Mar. 5, 2012. In the welcome
party of this year which was held after the first day of 2012 IBB Workshop
finished, 17 division professors and 42 graduate students including 20 new
graduate students attended.
The party started with a complimentary address by professor Wonhwa Cho,
and the 2012 JH fellowship award ceremony was followed. The JH
Fellowship was conferred on two new graduate students in division, JiYoung Seo and Seo-Yeon Bok by division chairman, professor Inhwan
Hwang.
After that, it was following by self introduction of all attending IBB students and division professors’ welcoming speech. It was good opportunity
for all IBB members of professors and students to know each other well
with conversation freely in a relaxed atmosphere.
Division is pleased to announce that 23 new graduate students, admitted
through the four rounds of entrance exams in 2011, joined IBB graduate
program (combined master’s and doctoral program) in 2012 spring semester. POSTECH is proceeding 3 times of entrance exams for graduate programs in the year of 2012.
If you would like more information about admission to IBB, please visit division website www.postech.ac.kr/ibb.
1. Self-inductions by IBB students
2. JH Fellowship award ceremony
3. Greetings from IBB professor Jonathan Sprent
02
Division News
The First Symposium of the Institute for Basic
Science was held in April 27, 2012
The first symposium of the institute for
basic Science (IBS) was held in different
places depending on research fields of
Mathematics, Physics, Chemistry and
Life Science on April 27, 2012. This symposium, organized by Institute for basic
science which was established with the
goal of creating a world-class research
institute in the basic sciences, provided
a good opportunity for scientist to exchange ideas and learn the latest
research trends including new and innovative technologies.
Professor Charles Surh in division was invited at the symposium as a speaker
presenting in the field of life science which was held at Daejeon Convention
Center (DCC), Daejeon. Professor Charles Surh presented with the title of ‘T
cells and commensal microbiota : homeostasis and mutualism’.
After the symposium, professor Charles Surh was appointed as the directors for the Institute for Basic Science (IBS) which is core research institute
established by the International Science and Business Belt.
1. Presentation by Prof. Charles Surh
2. Together with POSTECH members at the symposium
3. Audience at the symposium
POSTECH graduate program information
session was held in May 13, 2012 at the POSCO
Center in Seoul
POSTECH graduate program information session was held in May 13, 2012 at
the POSCO Center in Seoul. This information session is held every year in
Seoul to give more detailed information for the students interested in
studying at POSTECH graduate program with opportunity to meet their
preferred professors. Division takes
part in this information session as one of POSTECH graduate courses every
year since organized at 2009.
The chair of division graduate committee, Professor Sung-Ho Ryu introduced IBB graduate courses and regulations for the award of the degrees
and entrance examinations for admission. After that, division professors
and attending students had free conversation with questions and answers
in the relaxed atmosphere.
As the representative of division, Professor Wonhwa Cho, G-One Ahn, David
Somers and Sung-Ho Ryu attended the information session this year and
total 26 students visited division of IBB.
03
1. Introduction of POSTECH at the opening ceremony
2. Presentation on IBB program by Prof. Sung-Ho Ryu
3. Conversation with IBB professors
Division News
Immune Homeostasis & Regulation R&D Group
(IHRRG) Symposium held from Jun. 14 to 15, 2012
in Gyeongju
All members in IHRRG at the symposium
Immune Homeostasis & Regulation R&D Group (IHRRG) at POSTECH
held, for the first time, IHRRG Symposium from Jun. 14 to 15, 2012 for 2
days in Gyeongju.
In POSTECH, many laboratories from the various departments have been
focusing their efforts to elucidate the molecular and cellular mechanisms
of immune homeostasis and regulation as well as to translate their discoveries into clinical developments. The symposium aims to bring all the
immunology research groups at POSTECH together and provide the
opportunity to share their up-to-date research activities to promote
multi-laboratory and multi-disciplinary collaborations and lay a foundation for establishing a world-renowned immunology research hub at
POSTECH.
Ten professors at POSTECH and 65 graduate students studying in the
field of immunology attended this symposium.
The symposium was composed of 3 sessions with 16 speakers selected
from all attending students and the speakers presented the outcomes of
their research in order to share ideas with all members in IHRRG. The
symposium was completed with closing remarks by division overseas
professor Charles Surh.
It was good experience for the students studying in the field of immunology at POSTCH to obtain more information regarding their research
fields and get to know each other in the group.
1. Presentation at the symposium
2. Participants listening to a presentation
3. Closing remarks by Prof. Charles Surh
04
Division News
Joint symposium of Seoul St. Mary’s HospitalCRCiD, POSTECH IBB and Jilin Univ. IIJU was held
at Catholic University on Jun. 18, 2012
Joint symposium on Translational Research in Immunology was held at
Catholic University on June 18, 2012. It was organized by division of IBB,
POSTECH, Convergent Research Consortium for Immunologic Disease
(CRCID)- St. Mary's Hospital and Jilin University (IIJU), China. The overall
purpose of the symposium is to facilitate the advancement of both basic
and translational research in immunology by promoting mutual inspiration
and new collaborations.
The symposium started with opening remarks by Prof. Chul-Woo Yang,
chair of CRCiD, and was followed by each presentation
by the symposium speakers. As representative of
POSTECH, Professor Youngchul Sung, Joo-Yeon Yoo,
Seung-Woo Lee and Dr. Donghoon Choi gave a talk on
their research topics. Also students from POSTECH and
Catholic University took part in a poster session aimed
toward young researchers and had an opportunity to
present their major research achievement.
1. Presentation at the symposium
2. Together with all speakers at the symposium
3. Joint Symposium poster
2012 Summer IBB internship program held from
July 2 to 27, 2012 for 4 weeks
Division held 2012 IBB Summer internship program from July 2 to 27, 2012 for
4 weeks for the students who are interested in IBB graduate study. The purpose of this program is to give an opportunity to know more details about
IBB graduate courses to domestic junior and senior under-graduate students
and encourage them to apply for the IBB graduate program in the future.
Staying at campus dormitory, all attending students took part in the
research activities of laboratories where they were engaged in every day
and had firsthand experience of POSTECH campus life. On the last day of
the program, division conferred the completion certificate of IBB internship
program on participating students who finished the 4 weeks internship
program successfully and all students attending the
program had an opportunity to present their research
work conducted during the internship program.
Total 11 students were chosen to participate in the program this summer. Division is providing this program
to the students interested in IBB graduate study every
year at summer and winter vacation.
1. Together with all members attending the program
2. Lecture by Prof. Per-Olof Berggren
3. 2012 Summer Internship Program poster
05
Division News
Evening Festival for Bio-members at POSTECH
was held on July 12, 2012 at POSTECH Biotech Center
Special lecture by Mountaineer Young-Ho Hur
Evening Festival for Bio-members studying at POSTECH was held on July
12, 2012 at POSTECH Biotech Center.
This program is sponsored by chair of IBB, Prof. Inhwan Hwang and jointly organized by three bio-related departments at POSTECH - Department
of Life Science, Division of Integrative Biosciences and Biotechnology
(IBB) and School of Interdisciplinary Bioscience and Bioengineering (I-Bio).
The program is composed of special lecture, dinner buffet and house concert.
For the special lecture, Mountaineer Young-Ho Hur was invited as a guest
speaker and, with the title of “Constant challenges and overcomes”, he
gave a talk about why people should take the lead of their lives and how
he overcame the difficulties while he conquered 3 highest peaks of the
poles and 7 continents. It gave the audience hope and courage to achieve
anything if people set their sights on a goal.
For dinner, all audience moved to the outdoor and had dinner on the
lawn around POSTECH Biotech Center.
After dinner, house concert, composed of Piano Solo, Guitar Solo and
Piano concerto with 3 pianists started and played a couple hours making
wonderful performance to the audience.
The festival was a good chance for POSTECH Bio-members to come out to
relieve stress built up from studying and enjoy themselves with beautiful
music in a summer night.
Division expressed the deepest thanks to professor Inhwan Hwang who
presented this wonderful summer night festival at POSTECH.
1. Dinner buffet on the lawn
2. Musical performance by House concert
3. Evening festival for Bio-members at
POSTECH poster
06
Campus Talk
Expand your horizon
by interacting each other
Dr. Peter So. My work was to develop advanced nonlinear microscopy, more specifically high-speed twophoton scanning fluorescence microscopy. The new
system I developed could image samples much
faster than the conventional one, and it attracted
some of people’s interest for collaborative studies.
One of these was to visualize transdermal transport
of hydrophilic and hydrophobic drug models in large
sections while maintaining submicron resolution,
and the other was to screen mitotic recombination
in an animal model which was genetically engineered to carry YFP turn-on sensor of mitotic recom-
07
IBB is an interdisciplinary graduate program empha-
bination. Through these collaborative works, I found
sizing on both bioscience and biotechnology. IBB is
that learning other disciplines through collaboration
composed of faculty members of biology, chemistry
was really fun. We sat together during imaging and
in the science side, and mechanical, chemical engi-
talked about how the samples were made, how the
neering in the engineering side. Although most of
imaging were taken, how data would be analyzed
IBB students have biology background, there are still
etc. I also found that the more I learned about what
a few students from engineering and I think this
collaborators wanted to do, the better results we
diversity is an important asset of IBB. Interaction of
could get. A minor factor, which also helped collabo-
students from different backgrounds can help to
ration, was the floor map of MIT buildings. Most of
expand their horizon each other by exchanging
MIT buildings are connected each other so that you
knowledge of science and engineering. I like to tell
can go almost anywhere without going outside
you my personal story in order to emphasize the
(especially in the long winter season). After getting
importance and joy of learning both science and
the PhD degree I moved to Massachusetts General
technology.
Hospital (MGH) as a postdoctoral research fellow. It
I was trained as a traditional mechanical engineer
was to extend my research field to medicine and to
until my master degree: my research was elasticity of
learn new optical imaging technology. The laboratory
solid mechanics. I began my career in bioengineer-
I worked was supervised by Dr. Johannes de Boer, and
ing, when I entered Ph.D. program at Massachusetts
we did many translational clinical studies as well as
Institute of Technology (MIT) in 1997. I wanted to do
the development of new optical imaging systems. I
something new and found the booming of biomed-
was involved several clinical studies including burn
ical engineering at that time. The laboratory I worked
study, vocal fold study of patients. Clinical studies
was advanced microscopy laboratory supervised by
were quite intense, because they required smooth
Campus Talk
Learning technology will be
a long way to go. However,
you can start simply by
talking to your colleagues
from engineering. Simple
adaptation of technology
may ease your research in
some cases. If you are able
to keep your interest in
technology during
graduate school, it will
bring you to higher levels
of biological research.
operation of the custom built instruments. I remem-
ing graduate school, it will bring you to higher levels
ber I spent quite some time to improve the system
of biological research. Another thing I like to suggest
in both hardware and software. In these clinical
is to learn computational software such as Matlab.
studies, I tried to interact with medical collaborators
Matlab is mathematical software originally devel-
as much as possible. Medical doctors at MGH did not
oped for matrix calculation. Matlab is easy to learn,
have tight schedules like those in Korea, and we
and it allows you to do any kind of computation you
spent quite some time to discuss technology and
can think by learning in a few days. Examples are
experiment. Learning about the specific medical
statistical analysis, system modeling, and image pro-
problems I worked on was not difficult, because
cessing etc. In terms of hardware you may want to
there are many good internet resources maintained
upgrade your microscope by introducing new light
by NIH or other health organizations in the US.
sources or detectors, or you may even like to build a
Biology deals with complex systems and the under-
simple microscope for specific applications. When
standing of biological systems has been enhanced
you tried to do, you can always get some help from
with the help of technology. An example is invention
your colleagues of engineering or even from me as
of two-photon microscopy (TPM) and revolution in
well.
neurobiology: TPM enhanced knowledge of neurons
I wish that you will have lots of joy and do some
and related brain diseases by visualizing their behav-
good research by interacting with your colleagues
ior inside intact brain. I think that biology will be
during your time in IBB and will develop your careers
more heavily dependent on technology in the
as connecting people who know both science and
future, and the better you understand technology
technology.
the more opportunity you will have.
Learning technology will be a long way to go.
Written by Professor Ki-Hean Kim
in the division.
However, you can start simply by talking to your colleagues from engineering. Simple adaptation of
technology may ease your research in some cases. If
you are able to keep your interest in technology durIBB POSTECH NEWSLETTER Fall 2012
08
Campus Talk
Looking Back Through Time:
My First Year
smooth. Being a Global PhD Fellow, my advisor has
high expectation from me and from time to time I
felt like I couldn't meet his expectation. However,
this is part of the journey of learning as a graduate
student. It pushes me to work even harder to overcome my limitation. I know somewhere in my advisor's heart, the tough journey he gave me wasn't
meant to pull me down but knowing that I can do it
at the end of the day. Furthermore, knowing that I
am working with one of the best experts in the
field, this itself is a privilege.
Not all the time life in IBB Somers Lab is full of
The impromptu call for me to contribute an article
downs. It has its ups too. As IBB consist of many
to the newsletter can be thought of as very timely.
international students/researchers in this lab. Being
After spending hours of deciding what should I
a Korean in this "international" lab, this creates an
write, I decided to share my reflection of my first
opportunity for me to help assimilate my fellow col-
year experience as a graduate student in IBB. I
leagues into Korean life. This not only helps me in
would summarize the journey is like a rollercoaster,
my communication and people skills, which would
full of its ups and downs but full of wonders and
be very useful when I attend conference and do
excitements. Let me begin my story with the downs
some networking with international researchers, it
but I will end with the ups as an encouragement to
also helps my English tremendously.
all readers out there.
Being in the "international" lab also gave me some
Life as a graduate student is never easy. My research
"culture" shock. In Korea, we must address our advi-
is related to understanding the role of homodimer-
sor as Professor as a sign of deep respect. However,
ization of certain protein called TOC1 in the circadi-
my fellow colleagues address our advisor by first
an system of a plant. This means there are a lot of
name! To them, calling by first name shows a more
experiments involved. The experiments can be time
friendly gesture. I am still coming to term with this
consuming and it alters my own circadian system.
but hopefully soon enough I would have the
At times I have to spend long hours and even
courage to call my advisor by his first name.
“camp” in the lab. To make things worse, when the
Learning new culture from these international
results were bad, I do feel that all my efforts have
researchers has also opened my eyes to the world
not been paid off well. However, when the results
out there, which I have yet to experience.
are good, it really motivates me to work even better.
My advisor spends his time between here and the
The journey through my first year was never
States. No matter where he is, he still care about
09 IBB POSTECH NEWSLETTER Fall 2012
Campus Talk
My journey is indeed like
a rollercoster, no matter the
ups and downs, I appreciate
every moment of it as I
know each moment comes
with its priceless
experience that I would
appreciate for the rest of
my life.
our progress and we have weekly Skype meeting
ney of first year graduate student, I would be able
with him to update our weekly progress and get his
to the States for this opportunity. Thank you IBB and
opinion and further ideas of our research. I enjoy
OSU for making this possible for me. I hope to learn
this moment as I get to show some of the progress
as much as I can in the States and use every oppor-
I've made thus far, I get to see his face and he gets
tunity I have to apply it back in IBB when I return 3
to see mine. I get to listen to his nice English and
months later.
hope to improve myself more.
Looking back this one year, my journey is indeed like
In Korea, Teachers Day is a very important day. Our
a rollercoaster. However, no matter the downs and
lab gave our advisor a surprise teacher's day cele-
ups, I appreciate every moment of it, as I know each
bration. We prepared flowers, thank you card and
moment comes with it a priceless experience that I
even made a lab t-shirts for our advisor. To us he is
would appreciate for the rest of my life.
not only our "boss" and advisor; he is also like a
father, mentor and friend. He is like a SUPERMAN to
us and thus we made him this card. Our advisor was
surprise and I hope he was touched by our gesture.
This fall, I have been given opportunity to go to the
States for 3 months as an exchange student. Doing
exchange is almost a dream for most graduate students and being given this opportunity, I must say
Written by Hee-Young Yoo
who has studied in the IBB graduate program
since 2011 spring semester.
IBB does have a good reputation worldwide and I
am privileged to be able to do this. I could never
have imagined throughout my ups and downs jour-
10
Campus Talk
IBB Laboratory Tour
T cell Biology
Laboratory
Research Background
Domesticating the host is the better long-term strategy
for pathogens. We should think of each host and its
parasites as a superorganism with the respective
genomes yoked into a chimera of sorts.
Nobel laureate Joshua Lederberg (Science, 2000)
The immune system evolved to protect the host from
invasion by the microorganisms present in the environment. Despite the strong ability of the immune system to
repel infections by pathogenic microbes, it is now clear
that the immune system co-exists with vast numbers of
commensal microbiota in all the mucosal surfaces
exposed to the environment.
As the late Nobel laureate Joshua Lederberg presciently
suggested in 2000 that the microbes and their host
should be considered a “super-organism”, the commensal
microbiota of a typical adult human is comprised of
almost 1000 different species, is 10-times larger than the
host in terms of total cell numbers, and contains 100-150fold more genes than the host.
The vast genetic diversity of the commensal microbiota,
viewed as the microbiome, is increasingly appreciated as
being essential for the health of the host. The commensal
microbiota are beneficial to the host in many respects,
including aiding absorption of nutrients from food, production of vitamins, and protection from pathogenic
microbes. Imbalance of the commensal microbiota, called
dysbiosis, is thought to be responsible for many of the
host’s physical ills, including obesity, metabolic syndrome,
inflammatory diseases, cancer, allergies, asthma, and
autoimmunity.
The relationship between the host immune system and
the commensal microbiota is highly complex because
these microbes possess many of the same traits as pathogenic microorganisms. Hence, the immune system must
co-exist with commensal microbiota and maintain a state
of tolerance to self and innocuous environmental Ags, yet
be able to vigorously repel invasion by a wide spectrum of
pathogens. The various mechanisms operating to regulate
these responses are yet to be clearly defined, but they
probably converge and intertwine with each other indicating that our immune system needs to be viewed in the
11
context of a super-organism. Our lab is focused on how
the host immune system, especially adaptive immunity,
interacts and establishes mutualism with the commensal
microbiota and how such interactions affect the host tolerance to self and immunity to foreign antigens. For these
studies, we have established axenic (germ-free) mice facility and are preparing other necessary infrastructure to
perform projects that will increase our understanding of
these issues.
Location
Room 207,
POSTECH Biotech Center
Research area
Homeostasis between the
immune system and the
commensal microbiota
Role of commensal
microbiota in autoimmunity,
allergic diseases and
response to pathogens
Development and
homeostasis of naive and
memory T cells
Modulating T cells populations for treatment of cancer
and autoimmune diseases
n
Professors
Res. Assist. Prof.
n
Graduate Students
n
n
Member
Professors
Jonathan Sprent /
Charles. D Surh
Research Assistant Professor
Bo-Gie Yang
Post-doc Researcher
Kwang-Soon Kim
Students
Jun-Young Lee /
Ji-Sun Jung / Ju-Hee Kim /
Jaeu Yi / Kyung-Jin Jo
Technician
Tae-Kyu Kim /
Jung-Wook Seo
Administrator
Hyo-Jin Park
n
n
n
Technicians
n
n
n
Administrator
Post-doc.
Accomplishments
Faculty >>
Appointment
Professor Charles Surh was appointed
as the director for the Institute for Basic
Science (IBS). The selected director will
be provided with yearly financial support and given authorities such as overseeing overall operation and independence of research.
Publications
Byeang Hyean Kim
n S. P. Patil, H. S. Jeong, B. H. Kim. A lowmolecular-weight supramolecular hydrogel of riboflavin Chem. Commun., 48,
8901. (2012)
n S. -Y. Hwang, H. -Y. Sun, K. -H. Lee, B. -H.
Oh, Y. J. Cha, B. H. Kim and J. -Y. Yoo. 5’Triphosphate-RNA-independent activation of RIG-Ivia RNA aptamer with
enhanced antiviral activity, Nucleic Acids
Research, 40, 2724. (2012)
Charles Surh
n Carrette F, Surh CD. IL-7 signaling and
CD127 receptor regulation in the control
of T cell homeostasis. Semin Immunol.
24(3):209-17. Epub (2012)
n Sprent J, Surh CD. Interleukin 7, maestro
of the immune system. Semin Immunol.
24(3):149-50. Epub (2012)
n Boyman O, Krieg C, Letourneau S,
Webster K, Surh CD, Sprent J. Selectively
expanding subsets of T cells in mice by
injection of interleukin-2/antibody complexes: implication for transplantation.
Transplant Proc. 44(4):1032-4. (2012)
n Surh CD, Sprent J. TGFputs the brakes
on homeostatic proliferation. Nat
Immunol. 19;13(7):628-30.(2012)
David Somers
n Kim Y, Yeom M, Kim H, Lim J, Koo HJ,
Hwang D, Somers D, Nam HG. GIGANTEA
and EARLY FLOWERING 4 in Arabidopsis
exhibit differential phase-specific genetic
influences over a diurnal cycle.(2012)
n Somers D.E. The Arabidopsis clock: time
for an about-face? Genome Biol. 13(4):153.
(2012)
Dong-Woo Cho
n Hyun-Wook Kang, Dong-Woo Cho.
Development of an indirect stereolithography technology for scaffold fabrication
with a wide range of biomaterial selectivity Tissue Engineering, Accepted. (2012)
n Jin Woo Jung, Hyun-Wook Kang, Tae-Yun
..
Kang, Jeong Hun Park, Jaesung Park and
Dong-Woo Cho. Projection Image-generation Algorithm for Fabrication of a
Complex Structure using Projectionbased Microstereolithography
International Journal of Precision
Engineering and Manufacturing, Vol.13
No.3 pp.445-449.(2012)
n Aeree Kim, Dong-Hyun Kim, Hae-Ryong
Song, Won-Hwa Kang, Hak-Jun Kim,
Hong-Chul Lim, Dong-Woo Cho, Ji-Hoon
Bae. Repair of rabbit ulna segmental
bone defect using freshly isolated adipose-derived stromal vascular fraction
Cytotherapy, Vol.14 No.3 pp.296305.(2012)
n Jung Min Hong, Bum Jin Kim, Jin-Hyung
Shim, Kyung Shin Kang, Ki-Joo Kim, Jong
Won Rhie, Hyung Joon Cha, Dong-Woo
Cho. Enhancement of bone regeneration
through facile surface functionalization
of solid freeform fabrication-based threedimensional scaffolds using mussel
adhesive proteins Acta Biomaterialia,
Vol.8 pp.2578-2586.(2012)
n Jongwan Lee, Seung Yong Lee, Jinah Jang,
Young Hun Jeong, and Dong-Woo Cho.
Fabrication of patterned nanofibrous
mats using a direct-write electrospinning
Langmuir.(2012)
n Se-Jin Lee, Dong-Woo Cho, Jae-Bok Song.
Novel Sonar Salient Feature Structure for
Extended Kalman Filter-Based
Simultaneous Localization and Mapping
of Mobile Robots Advanced Robotics,
Vol.26 No.8-9 pp.1055-1074.(2012)
n Hwang SH, Kim SY, Park SH, Choi MY,
Kang HW, Seol YJ, Park JH, Cho DW, Hong
OK, Rha JG, Kim SW. Human Inferior
Turbinate: An Alternative Tissue Source
of Multipotent Mesenchymal Stromal
Cells Otolaryngology-Head Neck Surgery,
online published.(2012)
n Dong-Woo Cho, Jin Woo Lee, Jong Young
Kim, Taeyun Kang. Chapter 31 Solid
Freeform Fabrication Method Applied to
Tissue Scaffolds, Chapter contribution in
The Handbook of Intelligent Scaffold for
Regenerative Medicine Pan Stanford
Publishing, pp.609-631.(2012)
n Dong-Woo Cho and Hyun-Wook Kang.
(Textbook) Chapter 21
Microstereolithography-Based
Computer-Aided Manufacturing for
Tissue Engineering COMPUTER-AIDED
TISSUE ENGINEERING, Vol.868 pp.341356.(2012)
n Jeong Hun Park, Jinn Woo Jung, HyunWook Kang, Young Hoon Joo, Jung-Seob
Lee, and Dong-Woo Cho. Development of
n
n
n
n
n
a 3D bellows tracheal tracheal graft:
graft: Mechanical behavior analysis, fabricationion and an in vivo feasibility study
Biofabrication, Vol.4 No.3 pp.035004,
Online Published.(2012)
Jung-Seob Lee, Hwang Do Cha, Jin-Hyung
Shim, Jin Woo Jung, Jong Young Kim,
Dong-Woo Cho. Effect of pore architecture and stacking direction on mechanical properties of solid freeform fabrication based scaffold for bone tissue engineering Journal of Biomedical Materials
Research: Part A, Vol.100A No.7 pp.18461853.(2012)
Jin-Hyung Shim, Jung-Seob Lee, Jong
Young Kim, Dong-Woo Cho. Bioprinting
of a mechanically enhanced three-dimensional dual cell-laden construct for osteochondral tissue engineering using a
multi-head tissue/organ building system
Journal of Micromechanics and
Microengineering, Vol.22 No.8
pp.085014.(11pp) (2012)
Jin-Hyung Shim, Jung-Bo Huh, Ju Young
Park, Young-Chan Jeon, Seong Soo Kang,
Jong Young Kim, Jong-Won Rhie, DongWoo Cho. Fabrication of Blended
Polycaprolactone/Poly (lactic-co-glycolid
acid)/ -Tricalcium Phosphate Thin
Membrane using Solid Freeform
Fabrication Technology for Guided Bone
Regeneration Tissue Engineering, Part A,
Accepted.(2012)
Kwang-Sook Park, Kyoung Je Cha, In-Bo
Han, Dong-Ah Shin, Dong-Woo Cho, SooHong Lee, Dong Sung Kim. Mass-producible nano-featured polystyrene surfaces for regulating the differentiation of
human adipose-derived stem cells
Macromolecular Bioscience,
Accepted.(2012)
Hyun-Ju Kim, Jung Min Hong, Kyung-Ae
Yoon, Nacksung Kim, Dong-Woo Cho, JeYong Choi, In-Kyu Lee, Shin-Yoon Kim.
Early growth response 2 negatively modulates osteoclast differentiation through
upregulation of Id helix-loop-helix proteins Bone, Accepted.(2012)
Geunbae Lim
n Seong J. Cho, Hyoryung Nam, Taechang
An, and Geunbae Lim. Replicable and
Shape-controllable Fabrication of
Electrospun Fibrous Scaffolds for Tissue
Engineering. JOURNAL OF NANOSCIENCE
AND NANOTECHNOLOGY, accepted for
publication.(2012)
n June-Kyoo Lee, Kyung-Woo Park, GeunBae Lim, Hak-Rin Kim, and Seong-Ho
Kong. Variable-focus Liquid Lens Based
on a Laterally-integrated
Thermopneumatic Actuator, Journal of
the Optical Society of Korea, Vol. 16(1) p.
22-28.(2012)
n Taechang An, WooSeok Choi, Eunjoo Lee,
Seong J. Cho and Geunbae Lim.
Fabrication of Conducting Polymer
12
Accomplishments
n
Micro/Nanostructures Coated Gold
Nanoparticles, JOURNAL OF
NANOSCIENCE AND NANOTECHNOLOGY,
Vol. 12 (6)pp. 4975-4978.(2012)
Chang Sup Kim, Bong-Hyuk Choi, Jeong
Hyun Seo, Geunbae Lim, Hyung Joon Cha.
Mussel adhesive protein-based whole cell
array biosensor for detection of
organophosphorus compounds,
Biosensors and Bioelectronics,
accept.(2012)
Jonathan Sprent
n X Loebbermann J, Thornton H, Durant L,
Sparwasser T, Webster K, Sprent J, Culley
FJ, Johansson C, Openshaw PJ. Regulatory
T cells expressing granzyme B play a critical role in controlling lung inflammation
during acute viral infection. Mucosal
Immunol 5: 161-72. (2012)
n Boyman O, Letourneau S, Krieg C, Webster
K, Surh CD, and Sprent J. Selectively
expanding subsets of T cells in mice by
injection of IL-2/antibody complexes:
implications for transplantation tolerance.
Transplant Proc 44:1032-34. (2012)
n King C, Sprent J. Emerging cellular networks for regulation of T follicular helper
cells. Trends Immunol. 33: 59-65. (2012)
n Boyman O and Sprent J. The role of interleukin-2 during homeostasis and activation of the immune system. Nature Rev
Immunol 12: 180-90. (2012)
n Boyman O, Kreig C, Homann D, Sprent J.
Homeostatic maintenance of T cells and
natural killer cells. Cell Mol Life Sci 69:
1597-08.(2012)
n Chang P-P, Lee SK, Davey G, Duan G, Cho
J-H, Karapiah G, Sprent J, Heath WR,
Bertram EM, Vinuesa CG. Breakdown in
repression of interferon-gamma mRNA
leads to accumulation of self-reactive
CD8 T cells. J Immunol 189: 701-10. (2012)
n Polhill T, Zhang GY, HU M, Sawyer A, Zhou
JJ, Saito M, Webster K, Wang Y, Grey ST,
Sprent J, Harris DCH, Alexander SI, Wang
YM. IL-2/IL-2 Ab complexes induce regulatory T cell expansion and protect against
chronic proteinuric renal disease. J Amer
Soc Nephr in press. (2012)
n Surh CD and Sprent J. Guest Editors - IL-7
In The Immune System: Development
And Function. Sem Immunol 24: 149-240.
(2012)
n Sprent J and Surh CD. Editorial Interleukin 7, maestro of the immune system. Sem Immunol 24: 149-150. (2012)
n Surh CD and Sprent J. TGF puts the
brakes on homeostatic proliferation. Nat
Immunol 13: 628-30.(2012)
Joon Won Park
n Eung-Sam Kim, Chang-Kyoon Shim, Jae
W. Lee, Joon Won Park, and Kwan Yong
Choi. Synergistic effect of orientation and
lateral spacing of protein G on an on-chip
immunoassay, Analyst 137 2421. (2012)
13
n
Eung-Sam Kim, Jung Sook Kim, Yoonhee
Lee, Kwan Yong Choi, and Joon Won Park.
Following the DNA Ligation of a Single
Duplex Using Atomic Force Microscopy,
ACS Nano, 6108.(2012)
n
n
Kyong-Tai Kim
n Kim DK, Sambasivan S, Nam H, Kim KH,
Kim JY, Joo TH, Lee KH, Kim KT, and Ahn
KH. Synthesis of a two-photon absorbing
compound toward reactive fluorescent
probes: An application to probing
monoamine oxidase activity. Chem.
Commun. 48, 6833-6835.(2012)
n Lee KH, Kim SH, Kim DY, Kim S, and Kim
KT. Internal ribosomal entry site-mediated translation is important for rhythmic
PERIOD1 expression. PLoS One. 7,
e37936.(2012)
n Yang YR, Song M, Lee H, Jeon Y, Choi EJ,
Jang HJ, Moon HY, Byun HY, Kim EK, Kim
DH, Lee MN, Koh A, Ghim J, Choi JH, LeeKwon W, Kim KT, Ryu SH, and Suh PG. OGlcNacase is essential for embryonic
development and maintenance of
genomic stability. Aging Cell 11, 439448.(2012)
n Kim EK, Lim S, Park JM, Seo JK, Kim JH,
Kim KT, Ryu SH, and Suh PG. Human mesenchymal stem cell differentiation to the
osteogenic or adipogenic lineage is regulated by cAMP-activated protein kinase. J.
Cell. Physiol. 227(4), 1680-1687.(2012)
Per-Olof Berggren
n IB LEIBIGER, A CAICEDO & P-O BERGGREN.
Non-invasive in vivo imaging of pancreatic -cell function and survival - a perspectiv Acta Physiol (Oxf) 204, 178-185. (2012)
n R RODRIGUEZ-DIAZ, R DANDO, YA
HUANG, P-O BERGGREN, SD ROPER & A
CAICEDO. Real-time detection of acetylcholine release from the human
endocrine pancreas Nature Protocols 7:
1015-1023.(2012)
n The pancreatic beta cell as a paradigm
for advances in inositide research.CJ
BARKER & P-O BERGGREN. Advances in
Biological Regulation 52:361-368.(2012)
Sang Joon Lee
n S.Y. Jung and S.J. Lee. Development of a
compact X-ray particle image velocimetry
for measuring opaque flows, part II: 3D
velocity field reconstruction, Review of
Scientific Instruments, Vol.83(4), 046102.
(2012)
n K.H. Nam, E.S. Yeom and S.J. Lee.
Extracorporeal bypass model of blood circulation for the study of microvascular
hemodynamics, Microvascular Research,
Vol.83, pp. 372-375. (2012)
n D.H. Kwon and S.J. Lee. Impact and wetting behaviors of impinging microdroplets on superhydrophobic textured
surfaces, Applied Physics Letters, Vol.100,
171601. (2012)
S.Y. Jung, S.M. Lim and S.J. Lee.
Investigation of waterseepage through
porous media using X-ray imaging technique, J. of Hydrology, Vol.452, pp. 83-89.
(2012)
B.H. Kim, J.H. Lim and S.J. Lee. Synchrotron
X-ray microscopic computed tomography
of the pump system of a female mosquito, Microscopy Research and Technique,
Vol.75, pp. 1051–1058. (2012)
Young-Chul Sung
n So-Shin Ahn, Bo-Young Jeon, KwangSoon Kim, Jung-Yeon Kwack, Eun-Gae
Lee, Ki-Seok Park, Sang-Nae Cho, YoungChul Sung. Mtb32 is a promising tuberculosis antigen for DNA vaccination in preand post-exposure mouse models. Gene
Therapy;19(5):570-575(2012)
n Doo-Jin Kim, Kwang-Soon Kim, Mi-Young
Song, Sang- Hwan Seo, Su-Jin Kim, Bo-Gie
Yang, Myoung-Ho and Sung YC. Delivery
of IL-12p40 ameliorates DSS-induced colitis by suppressing IL-17A expression and
inflammation in the intestinal mucosa
Corresponding Clinical Immunology,
;144(3):190-199 [Epub ahead of print]
(2012)
Youngsook Lee
n Jaoon Y. H. Kim, J. W. Lee, W. S. Lee, H. H.
Ha, M. Vendrell, Jacqueline T. Bork, Y. Lee,
and Young-Tae Chang. Combinatorial
Solid-Phase Synthesis of 4,6-Diaryl and 4Aryl, 6-Alkyl-1,3,5-triazines and Their
Application to Efficient Biofuel
Production, ACS Comb. Sci., 14(7) 395398. (2012)
Graduate Students >>
Awards & Honors
Division graduate student Young-Eun
Kim was selected as the Global PhD
Fellowship awardees in the year of 2012.
The Global PhD Fellowship is a national
HR education program which supports
PhD students in domestic universities
with tuition and living expenses so that
they can focus on their study and
research. Division graduate student
Hee-Young Yoo was awarded this
Fellowship in the year of 2011.
Campus
Map
01.
02.
03.
04.
05.
06.
07.
08.
09.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
Administration Building(Head quarter)
Science Building I
Hogil Kim Memorial Hall
Science Building II
Science Building IV
Student Union Building
Science Building V
Science Building III
Auditorium
Mathematical Science Building
RIST Administration Building
RIST Research Building I
RIST Research Building II
RIST Research Building III
RIST Research Building IV
POSTECH Information Research Laboratories
LG Cooperative Electronics Engineering
School of Environmental Science and Engineering
Sports Field
POSCO International Center
Jigok Community Center
Student Dormitories
Graduate Student Apartments
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
Pohang Accelerator Laboratory
National Center for Nanomaterials Technology
Life Science Building
Machine Shop
Mechanical Engineering Laboratories Building
Wind Tunnels
Chemical Engineering Laboratories Building
Industrial and Management Engineering
Laboratories Building
Chemistry Building
Gymnasium
Indoor Tennis Courts
Faculty Apartments
East Gate
Nakwon Apartments
Tae-Joon Park Digital Library
POSTECH Biotech Center
Jigok Research Building
Pohang Institute of Intelligent Robotics
Graduate Institute of Ferrous Technology
Pohang Institute of Metal Industry Advancement
Main Gate
Log Cabin
Pohang University of Science and Technology
Division of Integrative Biosciences & Biotechnology
San 31, Hyoja-dong, Nam-gu, Pohang 790-784, Korea
Tel: +82-54-279-8282~8283 Fax: +82-54-279-8289 Homepage: www.postech.ac.kr/ibb

Newsletter Fall 2012

Transcription

Similar documents

Kim Says `I Do` to Botox!

Better Than Stock – Bike Feature

160226 - WorldCover

midwest - Kim Hoegger Home

23 June 2015 Balamory Kim writes the story

Kim`s Dream... - Disabled Sailing Association of Ontario

Staunton City Schools Robert E. Lee High School

View PDF - Eric Kim