Key Ingredients in the QV Range Moisturise all over
Transcription
Key Ingredients in the QV Range Moisturise all over
Moisturise all over •P atients with large areas of dry or sensitive skin will also benefit from bathing with QV Bath Oil. •Q V Bath Oil contains light liquid paraffin, which has better skin adsorption than vegetable oils or oatmeal baths.6 •T he water dispersible formula ensures that the skin is uniformly hydrated and as a result helps restore the skin’s natural suppleness and healthy glow. • QV Bath Oil is an ideal cleanser for infants and the elderly. Key Ingredients in the QV Range •G lycerin - An effective humectant that is capable of attracting and holding water. - It is an effective skin plasticiser.8 - It is non-toxic, non-allergic and non-irritating to the skin. - Cases of sensitisation to glycerin (glycerol) are rare. •L ight liquid paraffin - As an emollient, it promotes rehydration and suppleness of the skin.6,9 - It is adsorbed on the skin6 and provides an emollient film which reduces transepidermal water loss from the stratum corneum to the environment.10 •S oft white paraffin - Also known as petroleum jelly, soft white paraffin is an occlusive agent with excellent emoliency.12 - It is non-toxic, non-irritating and non-carcinogenic.11,12 - The hydrocarbon mix in petroleum jelly interacts directly with the lamellar lipid layers to produce its effects.13 INNOVATION It’s part of our DNA eTHICS From its inception as a family business in 1953, Ego has consistently delivered effective, high-quality and innovative products. We are committed to creating the best possible skin therapies for our customers. Ego’s heritage stems from a strong medical and ethical background. We operate with honesty and integrity across all aspects of our business and value the relationships we build with health professionals, customers and our staff. eNVIRONMENT Still proudly Australian-owned, Ego has led the way in the development, manufacture and marketing of innovative skin care products. We take our responsibility to the community and the environment seriously. Our aim is to improve people’s wellbeing; each year we provide significant support to many charities and community organisations and invest in dermatological education and research. eVERYBODY Ego has grown to become a world leader, producing a comprehensive skin and health care range for Australia and the world. From our very first batch of Pinetarsol to our very latest innovative skin care product, we always have your skin health in mind. That’s why millions of people trust Ego to help care for their skin every day. 1. Campbell M.A., “Investigations into the pH of Various Soaps and Skin Products available in New Zealand,” Pharm Jour of NZ 1979. 2.White M.I., Jenkinson D.M., Lloyd D.H., “The effect of washing on the thickness of the stratum corneum in normal and atopic individuals,” Br Jour of Derm, Vol 116, No. 4, April 1987, pp. 116, 525-530. 3. Cork M.J., “The importance of skin barrier function,” J Derma Treat 1997, 8:S7-13. 4. Fleischer A.B., Fleischer Jr. A.B., “The clinical management of itching: Therapeutic Protocols for Pruritis,” Informa Health Care, 2000, pp. 77. 5.Lucky A.W., Leach A.D., Laskarzewiski P., Wenck H., “Use of an Emollients as a Steroid – Sparing Agent in the Treatment of Mild to Moderate Atopic Dermatitis in Children,” Paedi Derm, 1997, 4:321-324. 6.Taylor E.A., “Cutaneous Adsorption of Bath Oils,” Arch Dermat 1963, pp. 87:369. 7. Hunting ALL, Encyclopedia of shampoo ingredients. Micelle Press, England. 1983, pp. 238. 8. Fishor A.A., Contact Dermatitis, (3rd ed.) Lea & Febiger, Philadelphia. 1986, pp. 249. 9. Taylor, E.A., “Oil Adsorption,” J. Invest. Dermatol., 1961, pp. 37, 69-72. 10. Blank, I.H., “Emollients” in The Chemistry and Manufacture of Cosmetics, (2nd ed.) The Continental Press, Florida. 1975, Vol. 3, Chpt. 3, pp. 15-24. 11. Hunting ALL, Encyclopedia of shampoo ingredients. Micelle Press, England. 1983, pp. 317. 12. H and book of Pharmaceuticals Excipients. A joint publication of the American Pharmaceutical Association and the Pharmaceutical Society of great Britain, The Pharmaceutical Press, 1986, pp. 195. 13. Umbach W., “Cosmeceuticals – The future of cosmetics?” Cosmetics and Toiletries. 110(11):33-40, 1995. 14. Brewster B. Aquaporins: Stimulating AQP3, Cosmetics and Toiletries, 123:6. p20-26. June 2008 15. Brander J.M. Pores in the epidermis: aquaproins and tight junctions (Review). Int J Cosmet Sci. 29:413-422. 2007. Always read the label and use only as directed. EGO PHARMACEUTICALS PTY LTD, 21-31 Malcolm Road, Braeside, 3195, Australia australia +61 3 9586 8800 toll free 1800 033 706 dubai +971 4258 8433 singapore +65 6562 7755 malaysia +60 3 7956 8868 new zealand toll free 0800 368 452 ‘Ego’ and ‘QV’ are trademarks of Ego Pharmaceuticals Pty Ltd in Australia and other countries. ©2010 Ego. [email protected] www.egopharm.com 80955 www.qvskincare.com.au Gently cleanse and moisturise. A LITTLE Ego EVERY DAY. QV emollient therapy for dry or sensitive skin conditions. Remind your patients to avoid soap. • Even ‘mild’ soap can be highly alkaline and can strip away the skin’s natural layer of protective oils.1 •S oap also reduces the thickness and number of cell layers in the stratum corneum leaving the skin dry and potentially susceptible to infection.2 Corneocytes Corneocytes Lipids DRY SKIN HEALTHY SKIN Remind your patients to moisturise frequently and all over. Environmental triggers Factors impairing epidermal barrier •E mollients have an indirect anti-inflammatory action and may have a direct anti-proliferative effect on the skin.3 •E mollients help to decrease the severity of atopic dermatitis and are important in preventing recurrence.3 • Emollient therapy also has a steroid sparing effect.3,5 Emollients restore epidermal barrier IL-1 Scratch Itch Secondary Cytokines Eczematous Lesions Inflammatory Mediators Itch Scratch Cycle - adapted from Cork MJ.3 The QV range is ideal for patients with dry or sensitive skin. •T he QV range consists of products which are pH balanced. This helps prevent disruption of the skin’s acid mantle thereby reducing the chance of irritation. • QV contains gentle surfactants to provide effective cleansing without irritation. • QV products contain high levels of emollients and gentle humectants. • QV products have been dermatologically tested and found to be non-irritating to the skin. •T he QV range is free from colour, fragrance, propylene glycol, lanolin and its derivatives making it ideal for sensitive skin types. •Q V products feel great on the skin which in turn can help to increase compliance and therefore efficacy of emollient therapy. •A ll products in the QV range are non-comedogenic (won’t block pores), and suitable for daily use. Glycerin transportation and skin hydration. AQP3 Water transport Glycerin transport Glycerin content Lipid synthesis Cell proliferation Cell migration • SC hydration • Skin elasticity • Barrier recovery Wound healing Proposed mechanism of AQP3 - adapted from Brewster B.14 Aquaporins (specifically aquaglyceroporins) are a family of proteins that form channels to facilitate water transportation across cell membranes.15 AQP3 co-transports water and glycerin into and out of the epidermis15 – Glycerin is an humectant – Where glycerin goes, water will follow Glycerin transportation, both topically and systemically through stimulated AQP3 (Aquaporin) channels has a direct impact on improved skin hydration, elasticity and barrier function recovery.14 • AQP3 are pH sensitive15 • At a pH of ~5, skin pH, AQP3 are inhibited • If the pH of the stratum corneum increases AQP3 become permeable. For example, if you use soap that has a high pH, the AQP3 will become permeable and water loss from the stratum corneum will increase. Thus causing the skin to dry out. •U se of a pH balanced soap alternative such as QV will help to increase glycerin transportation whilst not promoting water loss through the stratum corneum. Stratum corneum, pH ~ 5 AQP3 Epidermis, pH ~ 7 Dermis AQP3 - Glycerin transportation There’s a QV product specially tailored to cleanse and moisturise different levels of dry skin. It’s important for patients to realise that a complete cleanse and moisturise routine is the best way to help with sensitive skin. If they are using a soap alternative as a cleanser, then they should also make sure to moisturise afterwards. There are many QV products designed to suit varying skin types and severity of conditions. INGREDIENTS MOISTURISING CLEANSING RATING RATING HHH HHHH INDICATIONS CLEANSERS QV WASH Glycerin 10% Lightly foaming cleanser Moisturising pH balanced For normal or sensitive skin QV BAR HHH HHHH Lightly foaming cleansing bar pH balanced For normal or sensitive skin QV GENTLE Glycerin 15% HHHH HHHH Medium foaming cleanser Gentle blend of mild surfactants WASH Moisturising pH balanced For dry or sensitive skin QV BATH OIL Light Liquid Paraffin 85% HHHH HH Water dispersible bath oil Ideal for moisturising large areas Non-greasy Mild cleanser Suitable for infants and the elderly For dry or sensitive skin QV INTENSIVE Glycerin 60% HHHHH HHHH Highly moisturising Medium foaming cleanser MOISTURISING Gentle blend of mild surfactants CLEANSER Preservative free pH balanced For chronically dry skin MOISTURISERS QV SKIN Soft White Paraffin 5% HHH Light moisturising lotion Easy to apply LOTION All over body moisturiser For normal or sensitive skin QV CREAM Glycerin 10%, Light Liquid Paraffin 10%, Soft White Paraffin 5% HHHH Highly concentrated moisturising cream Ideal for areas that need extra hydration For dry or sensitive skin QV INTENSIVE BODY Light Liquid Paraffin 50.5%, Soft White Paraffin 20% HHHHH Preservative free Water free MOISTURISER QV LIP BALM Highly emollient balm For chronically dry skin Light Liquid Paraffin 42.5%, Soft White Paraffin 21%, Ricinus Communis (castor) seed oil 12.5%, Methoxycinnamate 4%, Butyl methoxydibenzoylmethane 2.5% HHHHH Soft soothing gel Protects and moisturises Unique applicator Suitable for daily use Cleansing and moisturising ratings have been developed based on the amount of moisturisers and cleansers in each product. Ratings are relative to products within the same category.