NFkB Pathway
Transcription
NFkB Pathway
IKK family 國區 IKKß Er.t閉目 Rb pAb Hu GTX50693 IKKß antibody Rb pAb Hu. Ms. Rat ICC/IF , WB GTX83085 IKKß antibody [10A2C5B3] Ms mAb Hu ELISA , IHC GTX12140 IKKß antibody [10A9B6] Ms mAb Hu IP , WB IKKa/ß (phospho Ser176) antibody Rb pAb Hu , Ms , Rat ELISA , IHC , WB IKKa/ß (phospho Ser180/Ser181) antibody Rb pAb Hu , Ms , Rat ELISA , IHC , WB GTX107582 IKKyantibody Rb pAb Hu ICC/IF , IHC-P , WB GTX12141 IKKy antibody [46B844] Ms mAb Hu WB GTX111350 IKKE antibody Rb pAb Hu ICC/IF , WB GTX63506 IKKE antibody [EPR4904] Rb mAb Hu FACS , ICC/IF , IHC , WB IKKE (phospho Thr500) antibody Rb pAb Hu . Ms. Rat 口 dd國 國 tþ GTX79040 咱國 tþ GTX85606 Your Expertise, Our Antibodies, Accelerated Discovery. 曲調控血 IKKß antibody IKK l Bv IKKE f1bn圓圓區姐回 GTX105690 tþ GTX79039 IKKy B叫加'1rirmi ICC/IF , IHC-P , WB NFKB Pathway 之J ELISA , IHC-P , WB KDa 170 13095 72- ~"一 55 一 43 一 IKKß antibody (GTX105690): ICC/IF analysis of PFA-fixed A431 cells IKKy antibody (GTX107582): ICCIIF analysis of methanol-fixed HeLa cells IKKE antibody (GTX l1 1350): WB analysis of 293T celllysate Regulators of NFKB pathway 區區 Bcl-10 E叫胸lriri'IiiT:1 GTX109159 BcI -10 antibody GTX112744 BcI -10 antibody GTX83215 BcI -10 antibody GTX111091 GTX39761 f1bn盟國E11ll!J Er.t閉目p Rb pAb Hu , Ms 個區區 IHC-P , WB Rb pAb Hu Ms mAb Hu , Ms MAL T1 antibody Rb pAb Hu ICC/IF , IHC-P , WB MAL T1 antibody [50] Ms mAb Hu IHC-P , WB GTX102471 NIK / MAP3K14 antibody Rb pAb Hu WB GTX113057 NAK antibody Rb pAb Hu WB GTX61299 NAK antibody [EP611 Y] Rb mAb Hu . Ms. Rat 也吾吾 TX12116 NAK antibody [108 A4 29] Ms mAb Hu MALT1 NIK NAK [4月 E8H8 , 4F8E3H8] TANK GTX59886 TANK antibody Rb pAb Hu. Ms. Rat NRAF GTX81783 NKRF antibody Rb pAb Hu 一一 -.- 們 A 34- ~- ELISA , FACS , ICC /l F, IHC ICC/IF , IHC-P , IP , WB ICC/IF , IHC , WB IHC , IP ELISA , IHC , WB un-4-4l D-7.qJqu KDa 55- A B C 43 一 ICC/IF , IHC-P , WB RU 35- 26 一 Lymphogenesis, B-cell Maturation 55TANK • Kinase Transcription F叫or Inflammation, Immune Regulation, Proliferation, SU lVival - - - - -.. Translocation ~ Ph叫ho ~ u川M 27 一 55 一 17 一 BcI-lO antibody (GTXI09159): WB analysis of (A) HepG2 , (B) Molt-4 , and (C) Raji cells 43 一 antibody (GTXll1091): ICC/IF analysis of PFA-fixed HeLa cells 恥IAL TI NAK antibody (GTX113057): WB analysis of (A) HeLa and (B) HepG2 cells TANK antibody (GTX59886): WB analysis of mouse small intestine tissue Iysate one class 1 member (p50 or p52) and one class 11 member (p65/ReIA , RelB or c-Rel). In the cytoplasm , NF-KB heterodimer is inhibited by IKB (inhibitor of NFKB). Upon activation by a variety of stimuli , including cytokines , T- and B- cell mitogens , virus and stress , IKB is phosphorylated by IKK (IKB kinase) and then undergoing degradation through ubiquitin 中 roteasome system . The free Application Reference NFKB heterodimer then translocates to the nucleus and activate transcription. NFKB signaling is critical for the regulations of NAK antibody [108A429] (GTX12116) Ogasawa悶, Nuclear factor開 KB (NFKB) is an ubiquitous transcription factor. It works only when two members form a heterodimer that comprises immune responses , survival and proliferation . Misregulation of NFKB pathway may cause inflammatory and autoimmune diseases , N. et al. (2011) J Clin Biochem Nulr. 48:154-60. (ICC/IF , IHC , WB; Hu) 叭叭 viral infection and cancer www.genetex.com GeneTex International Corporation Tel: 886-3-6208988 E-mail: [email protected] NFKB family 回m詞Emmm 區區 GTX100772 唱團ÞÞ GTX110585 NFKB p105/ GTX50377 帥 盡þ GTX79002 ÞÞ GTX27549 þ GTX85623 llbn圓圓扭扭扭 NFKB p105/p50 antibody 創世血 恥而吻 Rb pAb Hu NFKB p105/p50 antibody Rb pAb Hu NFKB p105/p50 antibody Rb pAb Hu . Ms. Rat NFKB p50 antibody Rb pAb Hu NFKB p105/p50 (phospho Ser337) antibody Rb pAb Hu , Ms , Rat NFKB1 (phospho Ser893) antibody Rb pAb Hu Hu ICC/IF , WB 47- ELl SA , GSA , IP , WB IHC , WB NFKB p105/p50 (phospho Se的07) antibody Rb pAb NFKB p105/p50 (phospho Se的27) antibody Rb pAb Hu , Ms , Rat 甸園 þ GTX50279 NFKB p105/p50 (phospho Se的32) antibody Rb pAb Hu , Ms , Rat Hu. Ms ICC/IF , IHC , WB WB IHC , WB ICC/IF , IHC , WB IHC , WB GTX50610 NFKB p100/p52 antibody Rb pAb GTX101150 NFKB p100 antibody Rb pAb Hu . Ms GTX27972 NFKB p52 antibody Rb pAb Hu . Ms. Rat IHC , IP , WB NFKB p100/p52 (phospho Ser865) antibody Rb pAb Hu . Ms. Rat ICC/IF , IHC , WB NFKB p100/p52 (phospho Ser869) antibody Rb pAb Hu . Ms. Rat ICC/IF , IHC , WB þ GTX79001 NFKB p65 antibody Rb pAb Hu GTX61185 NFKB p65 antibody [E379] Rb mAb Hu. Ms NFkB p65 / GTX50371 NFKB p65 antibody Rb pAb Hu . Ms. Rat ICC/IF , IHC , WB RelA GTX27970 NFKB p65 antibody Rb pAb Hu , Ms , Rat IHC-P , IP , WB NFKB p65 antibody [112A1021] Ms mAb Hu , Ms , Cow , Mk , P 旬 , Rat NFKB p65 (phospho Thr254) antibody Rb pAb Hu , Ms , Rat ICC/IF , IHC , WB þ GTX85622 NFKB p65 (phospho Ser276) antibody Rb pAb Hu , Ms , Rat ELl SA. Hu , Ms , Rat IHC , WB þ GTX78994 NFKB p65 (phospho Thr435) antibody Rb pAb Hu , Ms , Rat ICC/IF , IHC , WB Hu þ GTX50254 NFKB p65 (phospho Ser529) antibody Rb pAb Hu . Ms. Rat GTX102333 GTX61291 甸咱園 國 þ GTX78951 þ GTX50283 c-Rel NFKB p65 (phospho Ser536) antibody Rb pAb Hu . Ms. Rat Rel B antibody Rb pAb Hu. Ms IKBa 甸甸園 園 ICC/IF , IHC , WB Rel B (phospho Ser552) antibody Rb pAb Hu . Ms. Rat IHC , WB IHC , WB ICC/IF , IHC-P , IP , WB Rel B (phospho Ser573) antibody Rb pAb Hu , Ms GTX62544 c-Rel antibody [EPR2558] Rb mAb Hu ICC/IF , IHC-P , IP , WB GTX74165 c-Rel antibody Rb pAb Hu ELl SA , GSA , IP , WB IKBa antibody GTX61054 IKB口 antibody GTX50468 IKB口 antibody GTX12134 IKB口 antibody 47 - 一 -NF-kB p105 /50 I ' -p50 47 [6A920] NFkB pl05/p50 antibody (GTXII0585): ICC /l F analysis of PFA-fixed HeLa cells NFkB pl05/p50 antibody (GTX50377): WB analysis of HT29 cell Iysate using j1)blocl呵帥t峙 preincubated and 2) un-incubated GTX50377 Rb pAb Hu , Ms , Rat ICC/IF , IHC , WB Ms mAb Hu . Ms ICC/IF , WB IP , WB Rb pAb Hu . Ms. Rat ICC/IF , IHC , WB 咱國 þ GTX50681 IKB口 (phospho Tyr42) antibody Rb pAb Hu . Ms. Rat IHC , WB ICC/IF , IP , WB GTX63120 IKBß antibody [EPR5037] Rb mAb Hu GTX27547 IKBß antibody Rb pAb Hu . Ms. Rat GTX82797 IKBß antibody [7B4] Ms mAb Hu IKBß (phospho Ser23) antibody Rb pAb Hu , Ms , Rat GTX63006 IKBE antibody [EPR901 (2)] Rb mAb Hu GTX50609 IKBE antibody Rb pAb Hu , Ms IHC , WB ICC/IF , IHC-P , IP , WB ELl SA , IP , WB ELl SA , ICCIIF , IHC IHC-P ICC / 悴 , IHC-P , IP , WB IKBE (phospho Ser22) antibody Rb pAb Hu , Ms IHC , WB GTX59616 BcI-3 antibody Rb pAb Hu , Ms , Rat IHC , IP GTX15046 BcI-3 antibody [Ham150-3.5] Hm mAb Hu , Ms KDa A B C D 75 50 37 一 KDa ELl SA , WB A B C D 55 一 1-IBCL-3 75 一 50 37 11 35 一 ii16 I 32 一 I 26 (GTX l1 0521): WB analysis of celllysates. A) B) C2C12 IKBαantibody BCL斗, IKB 戶 antibody (EPR5037] (GTX63120): WB analysis of cell Iysates. A) Jurkat; B) HeLa; C) THP-1; D) MCF-7 IKBE antibody (EPR9 01(2)] (GTX63006): WB analysis of celllysates. A) THP-1; B) Jurkat; C) HeLa; D) A375 BcI -3 antibody (GTX59616): WB analysis of Jurkat celllysate (kD) NFkB p65 (phospho Ser536) antibody (GTX50098): WB analysis of (1) untreated and (2) TNF-treated HepG2 cells NFKB p105/p50 antibody (GTX110585) NFKB p50 antibody (GTX27549) Koya , T. et al. (2012) Am J Physiol Heart Circ Physio l. 303:H96-105 Adrianto , 1. el al. (2011) Nat Genet. 43:253-8. (EMSA) 可 Re lB antibody (GTX102333): IHC-P analysis of HeLa xenograft IKK family |KK口 antibody [Y 463] 、L Hu , Ms , Rat FACS , ICCIIF , IHC-P , IP , WB IHC , WB IKKa antibody Rb pAb Hu , Ms , Rat |KKa antibody [14A231] Ms mAb Hu , Ms |KKa (phospho Thr23) antibody Rb pAb Hu , Ms , Rat Rb pAb Hu , Ms IKK口 (phospho 大代 Accelerated Discovery ICC/IF , IHC-P , IP , WB Ser32/Ser36) antibody KDa AB 130 9572- IKK口 Our Antibodies Hu , Ms , Rat IKB口 (phospho 一一~ Application Reference Your Expertise Hu , Ms Rb mAb þ GTX50209 34 26 一 26 (kD) Rb pAb Hu Bcl-3 NFkB-p65 (pSer536) 且噩噩噩個 自調呵呵? Rb mAb 43 36- 36- c-Rel antibody [EPR25581 (GTX62544): WB analysis of cell Iysate. A) Daudi; B) HuT-78; C) K562 Ser32) antibody [EPR3148] 甸園 þ GTX50252 1 2 R閱單單旭正圈, [E130] 55- 85 NFKB p65 antibody (GTX I02090): IHC-P analysis of A549 xenograft IKB口 (phospho IKBE IHC-P , WB Hu 118 一 25 一 由相繭ll"ill1I:J GTX110521 咱國 þ GTX50317 ICC/IF , IHC , WB Rb mAb 11885 37 一 • ' -NF-kB p52 þ GTX62342 IKBß IHC , WB Rel B antibody [EP613Y] 1 2 50- NFkB p100/p52 antibody (GTX50610): WB analysis of HT29 cell Iysate using (1) blocking peptide-preincubated and (2) un-incubated GTX50610 區D lH!l. WB Rb pAb þ GTX50098 RelB IHC干 , NFKB p65 (phospho Ser311) antibody Rb pAb 47.5(kD) Re lB (phospho Ser573) antibody (GTX50283): WB analysis of (1) untreated and (2) TNF-treated HUVEC cells FACS , IHC-P , WB þ GTX78995 NFKB p65 (phospho Thr505) antibody 26 一 ICC/IF , IHC-P , WB FACS , ICCIIF , IHC-P , IP , WB 甸園 þ GTX50097 þ GTX50219 62 IKB family GTX102090 GTX13594 36(kD) þ GTX50324 前2 甸唱園 團 þ GTX79000 NF-kB p100 83 IHC-P , WB 甸甸園 園 þ GTX78998 NFkB p100/ 175 NRelB (pSer573) ICC/IF , IHC-P , WB IHC , WB KDa 250 15010075- 1 2 1 2 11885- Ser176/Ser180) antibody IP , WB IHC , WB WB www.genetex.com