Newsletter - Faculty of Medicine, Nursing and Health Sciences
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Newsletter - Faculty of Medicine, Nursing and Health Sciences
Newsletter Department of Biochemistry and Molecular Biology Issue 33: April 2013 NEWS AND EVENTS Our Latest PhD Graduates Khalid Mahmood Thesis: Computational algorithms for comparative genomics. Supervisor: James Whisstock Cecilia Isabel Naranjo Golborne Thesis: The role of palmitoylation in regulating the development of the embryo and the epidermis. Supervisor: Ian Smyth Sonia Teoh Thesis: Localisation and function of mammary serine protease inhibitor (maspin). Supervisor: Phil Bird Differences (and similarities) between the POTRA domain of TamA and BamA Courtesy: Matt Belousoff (Lithgow Lab) and Steve Heady Upcoming Seminar Dr Stephanie Gras (Rossjohn Lab): “The world of TCRs” Wednesday May 29th 4 pm Lecture Theatre M2 (Building 13) Followed by refreshments in 77 foyer. LATEST MEMBERS OF STAFF Lab Head Staff Member Position Travis Beddoe Mai Tran RF Peter Boag Vaiderky Annalingam Affiliate Steven Clavant Gareth Chadwick Affiliate Fasseli Coulibaly Shilpa Johnson Casual TA Fasseli Coulibaly Chan-sien Lay RA Roger Daly Brock Conley Scientific Officer Roger Daly Rachel Lee RF Roger Daly Ling Liu RF Terry Kwok-Schuelein Mojgan Torabi OT Trevor Lithgow Victoria Hewitt Casual RA Thomas Naderer Samih Ladkani Affiliate Anthony Purcell Laura Dagley Casual Jamie Rossjohn Tracy Josephs RF Jamie Rossjohn Phillip Pymm RF Jamie Rossjohn Kwok Wun RF Tony Tiganis Tariq Butt Visitor Tony Tiganis Manuel Rojo RF Tony Tiganis Faruk Sacirbegovic RF www.med.monash.edu.au/biochem Environmental Sustainability At Monash Anyone concerned with any environmental issues should contact Shani Keleher ([email protected]) or visit The Office of Environmental Sustainability (TOES) http://www.fsd.monash.edu.au/environmental-sustainability 2013 Monash University Three Minute Thesis (3MT) Competition Register now for the 2013 Three Minute Thesis competition! The Faculty of Medicine, Nursing and Health Sciences invites you to register for the Monash faculty rounds of the 3MT competition. Registrations are currently open and close midnight on 24 May 2013. About the 3MT Can you condense years of complex research into a three minute presentation that is interesting for a general audience? That’s the challenge that awaits graduate research candidates entering the Three Minute Thesis (3MT) competition, which is being held at every Australian university and universities in New Zealand, Asia and the South Pacific. The 3 minute thesis competition involves presenting a compelling speech using only one PowerPoint slide (no slide transitions permitted) on your thesis topic to an intelligent but non-specialist audience in just 3 minutes. The competition is an opportunity to: • Develop academic and research communication skills • Share the importance and potential impact of your research • Learn about research happening at Monash Entrants first compete at the faculty round, and winners will be selected to compete at the Monash 3MT final. The Monash 3MT finalist will then be invited to represent Monash University at the transnational final, which will be held at the University of Western Sydney. Central prizes include: • First place: $1000 plus the opportunity to represent Monash University at the transnational 2013 3MT final at the University of Western Sydney • Second place: $500 • Third place: $250 Please visit the Monash 3MT page for further information. http://intranet.monash.edu.au/migr/seminars/events/3-minute-thesis/ Biochem Success in the 2012 3MT Competition Winner 2: Michael Kraakman (Dept of Biochemistry) “Russell Crowe and Lego Man. An unbeatable recipe for conveying complex biological phenomena to lay audiences”. Michael also won the faculty competition. Runner up: Adam Shahine (Dept of Biochemistry) -“Severing the supply route between mycobacteria and host macrophages”. Photo L to R: Adam Shahine, Michael Kraakman with Winner 1, Jessica Van Gent (Dept of Anatomy) QUICK OVERVIEW OF WHAT TO DO WHEN AN EMERGENCY ARISES: 1. Remain CALM… 2. Yell out for a First Aider (don’t go looking for one yourself, get someone else to go looking) 3. First Aiders: Read MSDS before treating any chemical injury 4. First Aiders: Call Med Centre if necessary ext. 53175 5. First Aiders: Call the Safety Officer and/or Safety Representative as soon as possible Newsletter: April 2013, Issue 33 Department of Biochemistry and Molecular Biology Page 2 STUDENT SOCIETY POSTGRADUATE MATTERS Faculty Research Supervisor Accreditation Workshops (Level 1) - Online Registration Now Open The accreditation program is split into 2 workshops for prospective supervisors (Monash staff members only) from all departments within the Faculty of Medicine, Nursing & Health Sciences. Necessary Outlets for Tertiary Doctoral Research Students NOTDRS have welcomed new post-graduate students to the department with vigour holding a special Beer Club in their honour. NOTDRS Beer Club has thrown together many people from the department. Most recently, we were delighted to have Roger Daly join us for a beer and a chat. We look forward to many more successful events in the future; standby for laser tag or bare foot bowls. Attendance to both workshops is required. Workshop 1 Tuesday 11th June Are you interested in being involved in NOTDRS? Why not get in touch with Giuseppe ([email protected]) and join in the fun? Workshop 2 Tuesday 18th June Registrations from 9.20am, with each workshop concluding around 12.45pm To find out more about NOTDRS please visit: http://www.med.monash.edu.au/biochem/student-society.html Venue Or find us on facebook: http://www.facebook.com/groups.php?id=695417331&gv=12#/group. php?gid=86877543416 Auditorium, Japanese Studies Centre, Building 54, Clayton Campus (Opposite Faculty of Medicine Building 64) To apply for a place at the workshops, please register online: http://intranet.monash.edu.au/migr/ seminars/bookings/medicine/index.php *Registrations close Friday 7th June OHS MATTERS Queries: please contact Phyllis Di Palma (Research Degrees Office, Faculty of Medicine, Nursing & Health Sciences) on ext 20047 or email [email protected] The updated New 2013 Safety Manuals are ready and can be collected from just outside the Biochem Imaging facility 76G58. Old ones should be replaced with the new version asap and show in every lab area/room. Applications for the Mid-Year Round of postgraduate scholarships closes May 31: http://www.monash.edu.au/migr/ apply/application/guide/index.html Contact Mibel with any questions: [email protected] Link to MBio e-bulletin: http://www.med.monash.edu.au/ mbio-gradschool/e-bulletin.html All queries on Postgraduate matters: Please contact Prof Mibel Aguilar [email protected] Newsletter: April 2013, Issue 33 Computational Systems Biology Presentation by Professor Thomas Rattei Head of the Department for Computational Systems Biology University of Vienna 2pm - 3pm, Thursday 16th May Bld 76 Rooms 204/205 Professor Rattei’s work is mostly focused bacterial work pathogen Professoron Rattei’s is genomics, pathogen-host interactions asmostly well as structuring the protein focused on bacterial space. pathogen genomics, pathogenBacterial proteinhost secretion - key factoras in host-pathogen interactions interactions well as Protein secretionstructuring is a key virulence mechanism the protein space. of pathogenic and symbiotic bacteria. Thereby proteins can be transported from the bacterial cytosol directly into the eukaryotic host cell. This makes the investigation of segregated proteins (“effectors”) crucial for understanding the molecular bacterium-host interactions. Eased uptake of the pathogen, manipulation of the immune response and preventing apoptosis of the infected host cell are examples of the complex effects Page 3 Department of Biochemistry and that Molecular Biology are triggered by secreted bacterial proteins. Our group is developing novel computational methods addressing three major research questions DEPARTMENT’S PUBLICATIONS JANUARY/FEBRUARY/MARCH 2013 1. Ambaye, N.D., M.J. Gunzburg, R.C. Lim, J.T. Price, M.C. Wilce, and J.A. Wilce, The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents. ChemMedChem, 2013. 8(2): p. 280-288 2. Anderson, W. and I.R. Mackay, Fashioning the Immunological Self: The Biological Individuality of F. Macfarlane Burnet. J Hist Biol, 2013. E-pub: p. 1-29 3. Andrews, D.A., M. Xie, V. Hughes, M.C. Wilce, and A. Roujeinikova, Design, purification and characterization of a soluble variant of the integral membrane protein MotB for structural studies. J R Soc Interface, 2013. 10(79): p. 20120717.1-10 4. Beckham, S.A., J. Brouwer, A. Roth, D. Wang, A.J. Sadler, M. John, K. Jahn-Hofmann, B.R. Williams, J.A. Wilce, and M.C. Wilce, Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly. Nucleic Acids Res, 2013. 41(5): p. 3436-3445 5. Brown, K.A., N.U. Samarajeewa, and E.R. Simpson, REVIEW: Endocrine-related cancers and the role of AMPK. Mol Cell Endocrinol, 2013. 366(1): p. 170-179 6. Buszard, B.J., T.K. Johnson, T.C. Meng, R. Burke, C.G. Warr, and T. Tiganis, The Nucleus- and Endoplasmic ReticulumTargeted Forms of Protein Tyrosine Phosphatase 61F Regulate Drosophila Growth, Life Span, and Fecundity. Mol Cell Biol, 2013. 33(7): p. 1345-1356 7. Carey, K.T., K.H. Tan, J. Ng, D.R. Liddicoat, D.I. Godfrey, and T.J. Cole, Nfil3 Is a Glucocorticoid-Regulated Gene Required for Glucocorticoid-Induced Apoptosis in Male Murine T Cells. Endocrinology, 2013. E-pub: p. 1-13 8. Caruana, G., P.G. Farlie, A.H. Hart, S. Bagheri-Fam, M.J. Wallace, M.S. Dobbie, C.T. Gordon, K.A. Miller, B. Whittle, H.E. Abud, R.M. Arkell, T.J. Cole, V.R. Harley, I.M. Smyth, and J.F. Bertram, Genome-Wide ENU Mutagenesis in Combination with High Density SNP Analysis and Exome Sequencing Provides Rapid Identification of Novel Mouse Models of Developmental Disease. PLoS One, 2013. 8(3): p. e55429.1-13 9. Croft, N.P., S.A. Smith, Y.C. Wong, C.T. Tan, N.L. Dudek, I.E. Flesch, L.C. Lin, D.C. Tscharke, and A.W. Purcell, Kinetics of Antigen Expression and Epitope Presentation during Virus Infection. PLoS Pathog, 2013. 9(1): p. e1003129.1-13 CONTACT US: Department of Biochemistry and Molecular Biology Monash University, Ground Floor, Building 77, Wellington Road, Clayton VIC 3800 Australia Website: www.med.monash.edu.au/biochem Tel: +61 3 990 29400 Fax: +61 3 990 29500 Content and Layout: [email protected] Newsletter: April 2013, Issue 33 Photography: MNHS Multimedia Services Department of Biochemistry and Molecular Biology Page 4
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